Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A1BG ENSG00000121410 "Alpha-1-B glycoprotein" P04217 19 58345178-58353492 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1493 "liver: 1224.7" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 1548.5" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;RH-30: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB016673, HPA044252" Supported "Secreted to blood" NA NA 200000000000 51000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016673: AB_1611892, HPA044252: AB_2678876" "unprognostic (9.95e-2)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-2)" "unprognostic (4.19e-5)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (6.72e-2)" 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.1 1224.7 0.1 0.3 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.0 2.5 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.0 0.0 0.9 0.3 0.8 0.0 0.1 0.1 0.7 1.3 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.3 0.4 0.0 0.6 0.2 0.0 0.0 0.9 0.9 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 10.2 12.8 14.1 0.7 50.2 8.8 2.2 16.2 12.0 3.4 52.0 64.3 0.7 27.1 10.6 22.0 2.1 1.0 71.2 0.0 7.9 0.9 0.6 5.0 52.6 10.9 1.2 56.2 2.2 9.2 15.6 20.3 5.1 2.1 17.7 10.8 43.2 1548.5 25.1 8.4 1.7 0.1 20.3 110.9 66.0 2.1 1.2 49.4 115.6 0.0 60.8 3.1 15.5 0.0 8.7 5.4 0.0 1.2 94.4 11.1 0.0 2.0 15.0 5.5 26.3 29.2 43.8 4.1 7.9 1.5 3.7 1.9 52.6 0.7 0.2 0.6 ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 100.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 36.2" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: AB_10672606" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.5 2.7 100.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.5 0.3 0.5 0.3 0.3 0.6 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 8.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 36.2 0.5 0.0 1.2 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 3.4 4.2 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.7" "Group enriched" "Detected in some" 10 "Hepatocytes: 107.5;Proximal tubular cells: 101.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 192 "Hep G2: 2165.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 3010000 150000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 9.7 5.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 7.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.7 2.8 0.3 0.0 0.1 0.0 0.1 2.5 107.5 2.3 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 101.6 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 1.5 0.2 0.1 0.2 0.0 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138118305 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "liver: 426.9" "Group enriched" "Detected in some" 31 "Early spermatids: 65.4;Hepatocytes: 110.3;Late spermatids: 126.1" "Cancer enriched" "Detected in single" 77 "liver cancer: 20.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "Hep G2: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057002 Enhanced Approved Nucleoplasm,Cytosol No NA 61000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA057002: AB_2683308" "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "prognostic favorable (9.91e-5)" "unprognostic (6.11e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (6.87e-2)" "unprognostic (2.94e-1)" "unprognostic (9.68e-3)" "unprognostic (2.90e-1)" "unprognostic (5.80e-2)" "unprognostic (3.11e-1)" "unprognostic (1.67e-2)" 0.0 0.1 0.2 0.0 0.1 0.2 5.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 426.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 12.6 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 65.4 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.4 110.3 0.4 0.0 0.2 0.2 0.0 3.2 0.4 126.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.1 1.6 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.2 ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "liver: 212494.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 65190.0" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "Hep G2: 4500.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA 40000000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" 8.3 3.7 0.9 0.0 1.0 0.0 5.9 0.6 1.3 1.9 0.6 2.5 0.0 1.8 15.4 2.6 4.3 3.8 8.2 0.7 0.9 465.2 212494.0 6.7 1.3 0.7 0.8 2.5 1569.1 1.0 3.4 4.5 0.7 2.2 0.1 0.5 2.1 0.1 1.9 3.3 2.3 0.0 0.7 37.0 10.1 3.6 1.0 0.3 3.6 0.1 1.4 0.9 1.7 0.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 18.8 0.6 0.0 0.0 1.6 0.0 0.0 0.1 0.6 0.0 31.7 2.1 4500.0 0.0 117.1 3.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 17.0 0.2 0.0 0.1 2.0 0.0 4.0 0.0 0.1 2.1 95.1 0.0 0.0 3.2 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 13.5 0.0 1.4 0.1 0.1 7.0 0.6 32.9 0.1 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.7 0.7 1.0 0.8 0.1 0.0 0.0 1.0 187.5 0.0 0.0 0.0 0.0 0.0 43.4 18.9 0.1 13788.8 0.0 38.6 0.0 1.4 0.6 0.1 72.4 5.3 2.5 0.2 0.1 65.5 1.8 1133.8 0.2 273.8 11.1 0.5 4.6 0.0 0.0 0.1 1252.5 65190.0 8.5 0.0 0.2 0.0 0.0 1764.5 0.0 0.1 0.0 2.9 0.0 0.0 1.0 0.0 0.0 0.0 0.1 160.6 0.0 0.0 0.0 0.2 0.0 686.5 0.0 0.0 0.0 0.0 1.1 0.2 1.3 0.0 0.1 21.2 77.1 0.1 0.0 0.1 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 APOA5 "APOA-V, RAP3" ENSG00000110243 "Apolipoprotein A5" Q6Q788 11 116789367-116792420 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 216 "liver: 582.1" "Cell type enriched" "Detected in some" 88 "Hepatocytes: 1249.5" "Cancer enriched" "Detected in single" 489 "liver cancer: 112.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 55 "Hep G2: 35.6" "Not detected" "Not detected" "Secreted to blood" NA NA 114000000 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.57e-4)" "unprognostic (4.67e-3)" "unprognostic (5.57e-2)" "unprognostic (2.60e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-4)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 582.1 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 35.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.4 1249.5 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOC4-APOC2 ENSG00000224916 "APOC4-APOC2 readthrough (NMD candidate)" 19 44942238-44949565 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1258 "liver: 2221.0" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 147.1" "Cancer enriched" "Detected in some" 17 "liver cancer: 9.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "THP-1: 4.2" HPA055877 Supported NA NA "Cluster 62: Liver - Hemostasis" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA055877: AB_2682953" "unprognostic (1.45e-1)" "unprognostic (4.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (4.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" "unprognostic (2.01e-4)" "unprognostic (2.28e-1)" "unprognostic (2.88e-1)" "unprognostic (5.95e-2)" "unprognostic (1.68e-2)" 0.1 0.4 0.7 0.0 0.6 0.0 0.2 0.7 0.8 0.2 0.6 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.2 0.6 0.6 0.8 2221.0 1.7 0.0 0.7 0.7 0.0 0.3 0.0 0.8 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 1.2 0.1 0.4 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.7 0.8 0.6 0.6 0.7 0.7 0.8 0.7 0.9 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 147.1 2.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 7680.6" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "Hep G2: 1253.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" 0.9 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.2 0.2 0.3 0.8 2.5 0.1 1.0 0.2 0.8 2.8 0.6 0.2 0.0 31.9 17965.3 5.6 0.3 0.2 0.1 0.2 10.9 0.0 0.2 0.4 0.1 0.2 0.7 0.2 0.1 0.3 0.1 0.2 1.0 0.0 0.1 4.3 3.8 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 33.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 60.8 0.0 1.4 0.1 0.0 1.7 1.1 0.0 0.0 0.0 0.4 0.0 2.6 1.4 1253.3 0.0 6.4 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 1.4 0.5 0.2 0.0 0.2 0.1 0.6 31.5 0.0 0.8 6.4 0.1 0.0 0.9 0.4 0.0 3.4 0.1 0.2 0.0 0.0 0.0 1.7 0.2 0.1 0.1 0.0 0.8 0.1 2.9 15.3 2.4 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 12.3 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 183.0 0.6 0.0 0.0 0.0 0.0 0.2 3.9 0.8 0.2 0.2 0.0 5.2 0.0 109.7 0.2 2.3 0.6 0.0 0.0 0.1 0.0 0.0 120.0 7680.6 0.5 0.0 0.2 0.4 0.0 182.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.8 0.0 0.0 0.0 0.4 25.6 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 8.8 0.0 0.8 0.0 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ATF5 ENSG00000169136 "Activating transcription factor 5" Q9Y2D1 19 49928702-49933935 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 2479.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1412.6" "Cancer enriched" "Detected in all" 7 "liver cancer: 200.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 24.0;intermediate monocyte: 22.4;myeloid DC: 14.3;plasmacytoid DC: 38.5" "Group enriched" "Detected in all" 9 "dendritic cells: 38.5;monocytes: 24.0" "Cell line enhanced" "Detected in all" "HDLM-2: 313.2;Karpas-707: 523.4;THP-1: 452.4;U-266/84: 715.6;U-698: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030187 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA030187: AB_10601666" "unprognostic (2.09e-2)" "prognostic favorable (1.14e-4)" "unprognostic (9.38e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.52e-1)" "unprognostic (6.70e-2)" "unprognostic (3.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (3.39e-7)" "unprognostic (3.06e-2)" "unprognostic (8.06e-2)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" 40.7 61.4 11.7 31.7 11.6 21.4 35.6 10.7 15.2 14.9 9.3 19.6 28.3 16.2 9.8 18.0 22.9 14.4 17.3 12.2 14.7 26.1 2479.9 17.0 23.3 14.5 17.0 14.1 29.1 10.0 14.7 12.3 15.7 23.2 10.3 12.5 21.1 10.3 30.6 17.7 23.2 10.2 13.6 27.3 24.5 44.3 12.4 13.1 118.7 9.5 20.0 24.4 14.3 15.3 68.5 47.3 17.8 12.0 18.3 15.5 17.8 48.6 40.8 49.4 30.2 35.7 36.5 60.7 24.3 28.6 34.0 24.2 22.7 20.0 23.5 313.2 22.6 41.7 14.8 27.4 12.5 162.7 113.6 108.3 31.5 36.5 8.5 12.2 21.4 132.6 38.1 523.4 24.7 64.3 23.5 35.9 8.8 18.6 62.6 194.2 19.1 24.9 56.6 90.9 28.2 20.1 113.2 47.8 34.9 6.6 39.2 452.4 36.6 95.5 61.3 11.3 49.8 13.8 715.6 316.2 75.1 63.6 36.4 0.4 24.0 1.0 1.4 22.4 2.0 1.6 1.4 1.7 14.3 0.8 1.2 1.8 3.6 3.2 6.0 38.5 1.9 4.7 11.7 11.6 10.7 15.2 12.2 14.7 14.5 17.0 15.7 13.6 12.4 15.3 16.3 12.8 11.9 2.6 41.7 22.6 12.3 11.1 39.9 3.8 31.9 29.3 7.4 38.6 9.4 16.5 6.2 33.9 23.5 22.0 13.7 13.1 260.8 36.5 17.4 21.1 21.5 64.2 1.2 29.8 19.4 27.3 34.1 35.3 6.3 27.1 40.0 1412.6 82.5 92.5 1.8 21.0 2.0 59.4 172.3 134.3 13.4 51.2 40.9 2.8 259.9 17.4 8.2 0.5 1.6 20.0 20.6 16.6 118.1 24.8 49.0 47.9 9.6 7.5 13.1 18.0 24.2 15.0 11.3 37.7 24.0 35.6 15.1 23.4 23.4 18.4 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 4512.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Group enriched" "Detected in many" 7 "BJ hTERT+: 357.8;EFO-21: 738.6;Hep G2: 795.3;HSkMC: 534.8;SiHa: 209.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" 585.2 286.5 46.0 194.3 53.7 1.5 213.9 47.8 46.0 237.5 31.5 128.9 22.9 82.9 41.1 76.4 350.3 354.9 221.6 36.5 81.8 51.4 4761.3 176.0 68.2 143.3 99.2 228.1 182.7 17.9 21.8 17.7 116.4 35.4 76.5 11.7 155.6 57.4 36.6 51.4 156.4 123.0 89.9 7.1 107.9 41.1 103.4 34.1 92.4 52.0 126.4 363.3 101.3 121.9 65.0 23.0 0.0 0.1 10.8 36.0 74.7 5.2 357.8 6.8 12.6 3.6 49.5 1.9 738.6 0.3 54.2 46.6 0.2 43.1 6.9 24.0 0.5 3.1 31.2 795.3 16.3 6.2 9.1 534.8 12.8 60.8 27.3 9.5 0.0 0.0 2.1 0.8 0.2 1.0 0.6 1.6 1.5 0.7 0.1 0.4 5.0 0.3 32.1 6.2 0.5 0.5 209.5 0.1 0.5 0.1 17.2 8.8 3.5 5.7 7.4 4.8 3.6 1.6 4.8 4.5 75.1 4.5 0.3 1.7 1.3 0.6 0.3 2.5 0.2 0.5 0.2 0.1 0.7 0.5 0.2 0.2 3.0 1.3 13.3 0.5 0.1 0.9 46.0 53.7 47.8 46.0 36.5 81.8 143.3 99.2 116.4 89.9 103.4 121.9 36.4 76.9 473.9 0.7 29.4 27.5 14.7 141.5 0.6 0.7 19.5 23.4 14.5 783.5 422.5 16.5 0.0 1.4 2.0 0.2 5.9 494.1 45.9 23.0 63.5 26.2 0.0 209.9 0.4 136.7 1.4 482.2 17.9 57.7 5.1 0.1 124.9 4512.2 34.4 0.0 0.5 0.9 20.3 164.5 44.8 97.5 226.2 45.1 35.6 70.3 14.6 1.2 0.0 0.5 0.6 376.4 0.2 10.9 3.9 13.3 1.9 53.6 177.5 4.6 6.6 20.1 49.1 4.0 7.7 5.2 21.9 2.7 15.0 0.1 0.4 38.2 C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 471.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 597.6" "Cancer enriched" "Detected in many" 19 "liver cancer: 83.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 16 "CACO-2: 116.4;HeLa: 46.2;Hep G2: 151.6;OE19: 57.1" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" NA NA 265000000000 1100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA000925: , HPA051620: AB_2681554" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (2.07e-3)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-3)" "unprognostic (9.49e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (6.39e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (8.25e-2)" 3.0 0.1 0.0 3.4 0.0 0.0 1.8 0.0 0.1 2.8 0.0 3.6 3.8 0.1 0.0 0.2 0.5 3.1 0.1 0.0 0.0 0.4 471.3 1.5 0.4 0.0 0.0 44.2 9.1 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.5 0.0 0.1 0.2 4.4 0.6 0.0 0.4 8.4 0.7 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 5.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 46.2 151.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 12.8 2.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 7.3 2.2 0.5 54.3 3.2 0.0 0.0 1.0 0.2 10.2 1.9 11.4 4.1 0.7 0.1 0.8 1.8 8.0 0.1 88.8 0.3 3.4 5.6 0.8 0.0 0.3 9.7 597.6 2.1 0.0 0.2 5.6 0.0 13.1 0.3 2.8 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 69.2 15.9 0.0 0.1 0.2 4.3 0.0 2.2 0.0 0.0 1.1 0.4 0.1 0.4 0.0 0.0 0.1 1.1 143.8 4.8 0.1 C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120952335-121050275 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 433.7" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 538.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 28.4;Hep G2: 30.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029339 Supported "Secreted to blood" NA NA 113000000000 39000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" 2.9 1.7 2.5 1.1 3.4 2.2 2.5 2.4 2.6 3.0 3.5 2.8 3.9 2.7 2.7 1.6 3.0 1.5 1.3 2.2 2.6 4.8 433.7 7.0 2.1 2.9 2.9 3.3 14.9 2.6 3.1 0.9 3.2 3.2 1.6 3.5 1.4 2.2 0.5 3.8 3.9 1.9 2.8 1.5 5.8 1.6 2.8 1.2 2.0 1.2 1.7 2.6 2.1 4.5 1.6 28.4 6.4 11.3 8.0 9.2 0.2 3.4 3.5 0.9 2.0 0.8 2.8 4.1 0.1 1.8 3.8 11.0 0.3 0.3 1.5 0.9 0.0 1.8 1.5 30.4 1.5 1.0 0.7 4.1 0.5 2.0 3.7 1.8 1.0 1.6 0.7 3.8 2.2 5.6 0.4 0.2 1.7 7.0 10.9 2.5 2.8 0.4 1.7 0.8 1.6 6.5 1.6 0.0 2.7 4.4 2.2 3.7 1.3 2.8 0.2 7.5 3.4 2.3 1.8 1.7 2.2 3.8 6.8 0.0 0.3 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 3.4 2.4 2.6 2.2 2.6 2.9 2.9 3.2 2.8 2.8 4.5 0.8 6.4 28.6 30.0 3.5 1.0 1.0 0.5 1.8 4.8 2.2 1.3 0.8 32.9 7.1 1.8 0.0 0.1 0.1 0.4 1.9 0.2 1.8 1.1 2.2 1.4 0.0 12.0 7.3 0.4 0.0 2.9 2.0 0.8 0.0 3.1 7.5 538.3 1.9 6.7 9.4 1.0 0.0 16.3 1.0 2.8 3.1 3.5 0.0 6.5 2.3 3.2 2.1 25.6 25.4 0.7 3.8 9.1 0.1 0.7 1.0 6.8 3.8 2.6 0.0 4.0 1.6 7.5 2.5 2.0 1.3 0.0 1.4 2.8 2.0 0.6 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C8G ENSG00000176919 "Complement C8 gamma chain" P07360 9 136945185-136946975 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 564.4" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1134.7" "Cancer enriched" "Detected in all" 58 "liver cancer: 260.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HMC-1: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046269 Approved "Secreted to blood" NA NA 2800000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA046269: AB_2679606" "unprognostic (5.00e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.94e-1)" "unprognostic (4.53e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-3)" "unprognostic (2.79e-1)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (2.96e-2)" "unprognostic (3.00e-1)" "unprognostic (5.02e-3)" "unprognostic (2.16e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" 0.3 1.5 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.3 0.0 1.2 31.2 0.4 0.9 0.5 0.4 2.5 1.3 0.1 0.1 2.3 564.4 0.3 0.1 0.1 0.1 0.1 0.3 0.0 0.6 0.0 0.2 0.4 0.3 0.0 0.4 0.1 3.1 0.3 17.8 0.0 0.1 2.1 1.3 2.3 0.1 0.2 0.7 0.0 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.4 0.0 0.0 41.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 1.0 0.0 0.0 0.3 2.3 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.7 28.6 0.3 0.0 2.1 0.4 1.1 25.0 0.0 0.2 0.9 0.1 0.1 0.7 1.8 8.0 0.2 0.8 1.0 0.1 0.0 0.3 8.9 1.2 17.5 1134.7 0.3 0.0 0.2 5.0 0.0 25.3 0.2 1.5 0.0 0.2 0.0 0.0 0.0 1.1 4.1 0.5 0.1 0.5 4.7 0.7 0.0 0.4 122.3 6.7 0.1 0.5 0.0 0.3 0.3 0.7 0.6 0.5 0.4 3.4 1.8 0.2 2.0 0.2 CCDC152 LOC100129792 ENSG00000198865 "Coiled-coil domain containing 152" Q4G0S7 5 42756818-42802439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 178.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 43.4;Spermatocytes: 103.0;Spermatogonia: 37.8" "Cancer enhanced" "Detected in many" "liver cancer: 3.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HeLa: 13.6;JURKAT: 13.3;U-2 OS: 23.5;U-266/84: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036240 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "HPA036240: AB_10671242" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (3.14e-2)" "unprognostic (1.44e-3)" "unprognostic (3.24e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (6.25e-3)" "unprognostic (9.08e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-1)" "unprognostic (2.33e-3)" "unprognostic (5.40e-2)" "unprognostic (4.63e-2)" "unprognostic (2.14e-3)" 7.5 5.7 2.3 2.2 5.4 1.5 6.5 4.6 2.9 6.0 2.9 5.2 3.9 3.0 0.6 2.2 4.1 4.9 7.8 2.1 4.7 8.6 178.0 6.1 7.4 5.8 5.1 8.3 4.0 0.0 7.8 2.3 6.6 4.6 0.3 2.2 2.7 0.3 1.8 3.3 13.3 0.4 4.0 14.9 4.5 5.0 4.6 4.0 3.3 0.6 2.6 2.6 4.9 7.1 0.4 0.1 1.0 0.1 3.2 4.1 0.0 5.7 0.1 0.0 0.4 0.0 0.3 0.0 0.3 2.6 4.3 4.6 0.0 0.0 0.5 0.1 0.4 0.2 13.6 5.5 3.2 0.1 0.0 5.3 0.0 2.3 0.0 8.5 1.8 13.3 0.6 1.2 0.1 0.0 0.1 0.2 0.1 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.4 6.5 0.0 0.1 0.0 4.7 0.4 0.1 0.1 0.2 23.5 5.2 0.2 0.1 16.8 0.2 6.9 0.2 0.1 0.0 0.1 0.1 3.1 0.6 3.7 2.0 2.3 3.9 0.6 2.7 3.0 4.7 0.2 5.1 0.3 8.3 1.6 1.0 2.3 5.4 4.6 2.9 2.1 4.7 5.8 5.1 6.6 4.0 4.6 7.1 4.9 60.9 43.4 3.9 10.2 3.7 0.3 0.7 2.2 15.8 1.9 1.5 11.7 2.8 7.6 1.8 0.0 1.6 6.0 2.4 0.0 0.8 14.9 2.3 11.1 4.3 1.2 10.3 2.6 1.1 1.0 17.7 0.0 3.1 9.5 5.3 7.1 5.1 2.6 33.7 9.3 2.9 2.0 14.4 5.6 7.4 6.5 8.0 3.6 1.0 0.9 34.2 21.6 7.5 13.0 1.9 3.0 7.5 3.4 0.3 6.4 0.7 3.9 2.7 0.0 13.0 5.0 103.0 37.8 3.5 4.0 1.8 9.1 10.5 1.3 0.3 CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "liver: 120.3" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 262.0" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 10.1" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 2780000 23000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" 0.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.2 0.5 0.2 0.2 0.0 0.0 0.3 120.3 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.0 2.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 262.0 0.0 0.0 0.0 0.2 0.0 4.1 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918713 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 432 "liver: 123.9" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 62.6" "Cancer enriched" "Detected in single" 145 "liver cancer: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 170000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.97e-1)" "prognostic favorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (4.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 123.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.2 62.6 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196977556-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1675 "liver: 167.5" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 102.7" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726" Supported "Secreted to blood" NA NA 1900000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 102.7 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524155-126543291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 59.6;testis: 18.3" "Group enriched" "Detected in some" 5 "Early spermatids: 104.0;Hepatocytes: 40.3;Spermatocytes: 126.2" "Group enriched" "Detected in many" 4 "liver cancer: 25.0;renal cancer: 6.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 5 "eosinophil: 155.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 155.2" "Group enriched" "Detected in some" 8 "CACO-2: 15.6;Hep G2: 28.4;NB-4: 19.0;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA067960 Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA067960: " "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (6.42e-4)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (8.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (5.16e-2)" "unprognostic (6.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-2)" 0.3 0.4 0.2 0.4 0.2 0.6 0.1 0.0 0.3 0.1 0.0 0.9 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.3 0.2 3.2 59.6 0.6 0.1 0.4 0.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 1.0 0.0 0.4 3.5 0.4 18.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.7 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.7 0.3 28.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.9 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.1 33.0 155.2 0.0 20.5 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 30.7 0.0 17.5 0.0 0.0 13.1 0.2 0.2 0.0 0.3 0.3 0.2 0.4 0.5 0.2 0.4 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 104.0 0.6 0.0 0.1 1.2 5.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.7 40.3 13.1 0.0 0.0 1.0 0.0 7.5 1.3 16.9 1.5 6.2 0.0 1.9 7.2 0.0 0.0 0.0 0.1 0.0 2.8 1.2 0.3 0.0 8.5 9.9 0.1 0.0 0.0 0.0 0.0 126.2 2.8 0.0 0.0 0.3 0.2 0.0 1.8 0.0 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 1871.4" "Cell type enhanced" "Detected in many" "Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "EFO-21: 318.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" NA NA 160000000000 440000000000 "Cluster 62: Liver - Hemostasis" "Cluster 38: EFO-21 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 13.0 2.3 17.9 2.2 18.1 0.9 20.8 18.7 29.8 70.2 129.2 13.0 9.8 14.8 0.0 5.6 8.3 1.1 39.2 17.5 33.0 9.5 1871.4 13.4 18.9 28.1 20.3 0.8 6.5 3.9 28.6 3.4 24.9 7.9 16.4 246.5 39.9 0.9 2.6 13.0 20.8 2.4 19.2 23.1 3.0 1.5 20.1 0.5 16.1 8.3 20.0 23.9 2.3 29.0 0.2 18.8 15.6 0.0 3.3 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 318.8 0.0 29.4 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.4 32.7 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 2.5 5.4 0.0 0.0 0.0 0.4 6.7 16.2 0.0 0.2 0.3 1.0 0.1 0.4 0.0 0.4 0.0 0.2 1.7 0.2 0.2 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.1 18.7 29.8 17.5 33.0 28.1 20.3 24.9 19.2 20.1 29.0 2.3 19.2 76.6 3.3 10.6 3.3 8.3 28.6 0.6 6.9 14.0 0.6 0.6 65.8 558.1 9.2 6.2 0.1 0.3 0.1 0.0 83.4 0.9 190.5 51.0 12.6 0.0 34.7 1.5 21.4 0.2 16.3 0.0 406.0 2.5 0.1 34.6 1687.2 0.6 5.0 1.4 0.2 8.2 44.6 6.9 1.2 0.3 4.0 0.0 6.5 1.6 720.5 1.0 0.5 2.0 69.3 0.0 0.4 0.3 19.5 0.0 0.3 318.4 24.8 0.0 0.8 15.3 0.0 0.1 0.8 2.6 0.3 4.9 0.1 0.1 79.0 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 81.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 37.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 141.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 37.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.6 4.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 218.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 171.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "Hep G2: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA004732 Uncertain "Secreted to blood" NA NA 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" 0.4 3.0 0.7 0.4 0.6 1.5 0.2 0.6 1.1 0.2 0.0 0.2 0.0 0.4 0.4 0.1 0.2 0.4 1.0 0.7 0.8 14.7 218.6 0.2 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.2 0.2 1.1 0.2 0.1 0.1 0.6 0.2 0.2 0.0 1.2 0.4 0.7 0.4 0.1 0.3 0.0 0.2 0.1 0.0 1.1 0.2 0.1 0.3 0.3 0.1 0.8 0.2 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.3 0.8 0.4 0.5 0.1 0.0 0.2 0.1 0.2 0.3 0.6 61.8 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.5 0.6 0.0 0.3 0.2 0.3 0.3 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.2 1.4 1.6 0.2 2.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.7 0.8 0.2 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 171.8 0.2 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CTH ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Calmodulin-binding, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 122.9;ovary: 34.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 38.0;Hepatocytes: 141.6" "Group enriched" "Detected in all" 5 "liver cancer: 30.0;testis cancer: 8.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 39.7;Karpas-707: 63.8;SK-MEL-30: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced NA NA 220000 "Cluster 19: B-cells - Humoral immune response" "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA021591: AB_1847321, HPA023300: AB_1847322" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" "unprognostic (7.66e-2)" "unprognostic (2.45e-3)" "prognostic favorable (8.69e-4)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-3)" "unprognostic (5.05e-3)" "unprognostic (3.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.26e-1)" 4.3 12.9 3.4 1.3 3.1 3.4 2.9 3.3 4.0 2.5 4.5 5.1 5.2 2.2 1.6 4.5 3.8 1.8 2.4 3.3 3.6 13.5 122.9 3.1 0.9 3.4 3.7 34.4 17.0 1.4 2.9 1.1 3.4 4.3 6.2 8.1 2.5 2.1 3.6 1.2 5.3 1.3 2.7 1.0 7.4 4.1 3.7 0.6 7.7 2.9 1.3 2.2 1.9 3.2 10.2 1.5 7.1 10.0 8.5 4.8 15.0 4.3 4.1 3.8 15.7 3.2 6.4 5.8 3.4 3.1 9.3 4.9 27.3 3.1 7.2 17.3 5.9 7.0 5.1 9.4 39.7 7.8 1.7 7.5 24.4 7.5 8.8 1.5 3.2 11.9 14.0 63.8 2.2 3.2 2.7 1.9 7.2 4.2 5.9 3.0 3.7 16.2 7.3 0.1 3.9 3.3 6.6 7.7 85.7 13.3 2.6 4.6 1.1 1.2 7.7 5.7 4.1 23.8 15.3 3.1 9.8 16.1 3.1 0.8 0.3 0.1 1.2 0.2 2.1 2.2 1.1 1.7 0.5 1.7 3.2 1.5 0.4 0.2 0.2 0.7 0.3 0.6 3.4 3.1 3.3 4.0 3.3 3.6 3.4 3.7 3.4 2.7 3.7 3.2 2.8 6.4 5.6 16.6 6.7 2.5 8.0 2.2 6.2 9.4 6.2 5.8 1.9 5.7 2.5 5.5 10.4 0.8 5.5 16.1 11.7 1.8 27.2 38.0 6.4 3.3 3.0 7.4 7.8 4.2 1.8 13.6 14.8 19.7 0.0 1.9 3.9 141.6 1.2 0.0 7.4 7.9 2.0 3.5 5.7 5.2 1.2 4.7 19.6 1.9 0.0 4.4 0.0 7.1 4.2 6.4 12.9 4.1 10.8 4.0 11.1 29.2 0.7 11.6 0.0 2.8 17.7 1.4 0.6 4.8 2.0 0.8 11.2 4.5 9.1 3.8 CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "liver: 2.0" "Group enriched" "Detected in some" 8 "Club cells: 2.0;Early spermatids: 4.2;Late spermatids: 3.7" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 71 "liver: 152.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 195.3" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.6 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 152.5 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 24.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 11.0 195.3 0.0 0.0 0.1 0.8 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.9 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 320.0" "Group enriched" "Detected in many" 35 "Hepatocytes: 512.8;Proximal enterocytes: 465.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.8" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.2 0.0 0.3 0.3 0.1 0.8 0.2 0.1 0.3 0.3 3.7 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.3 320.0 0.1 0.1 0.2 0.0 0.2 0.8 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 11.7 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.8 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.0 1.1 5.5 0.7 0.5 0.7 1.3 2.8 7.3 1.1 1.4 0.4 2.8 0.7 1.8 2.1 0.1 0.6 2.9 1.9 0.7 3.1 0.8 0.6 0.6 1.2 0.0 6.5 0.6 0.1 0.3 4.1 1.4 0.0 0.7 5.7 512.8 0.1 11.8 9.4 7.6 0.0 5.6 0.0 13.6 0.0 0.4 0.0 0.0 0.1 0.7 0.0 5.0 4.9 0.7 11.3 1.5 0.4 0.6 465.2 0.5 1.3 2.3 0.0 0.4 2.1 0.8 0.4 0.6 1.1 0.4 1.0 0.1 3.4 0.3 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 920.2" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;SK-BR-3: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" 0.3 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.9 0.2 0.1 0.5 0.1 0.2 0.1 14.4 404.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 1.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.9 920.2 0.1 0.0 0.0 0.0 0.0 10.7 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 47.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.6 0.0 0.1 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.4 234.6 0.0 0.0 0.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.9 0.0 5.3 0.2 0.2 0.1 0.0 2.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.7 47.2 0.0 0.0 0.0 0.2 0.0 2.9 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGF21 ENSG00000105550 "Fibroblast growth factor 21" Q9NSA1 19 48755524-48758333 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 106 "liver: 84.1" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 116.4" "Cancer enriched" "Detected in single" 315 "liver cancer: 33.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HHSteC: 1.4;U-2 OS: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061286 Supported "Secreted to blood" NA NA 254000 73000 "Cluster 62: Liver - Hemostasis" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061286: AB_2684466" "unprognostic (1.64e-2)" "unprognostic (3.62e-1)" "unprognostic (3.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1123.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 412.3" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 34.6;ASC TERT1: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 27.2 12.4 2.5 0.9 2.7 0.4 6.8 2.5 3.6 1.2 2.3 1.4 1.8 1.3 3.0 5.1 13.3 1.8 4.2 2.3 2.6 14.0 1123.3 18.7 4.9 5.0 2.7 0.3 4.5 4.2 4.3 0.2 3.1 1.1 0.7 0.1 5.1 0.4 4.6 4.3 2.2 1.6 4.0 0.4 3.9 0.5 2.8 1.4 2.6 3.1 9.1 1.0 0.9 2.6 0.0 0.0 0.0 0.0 34.6 26.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 7.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 2.5 3.6 2.3 2.6 5.0 2.7 3.1 4.0 2.8 2.6 2.7 12.8 0.5 0.0 0.7 0.4 0.4 2.7 0.0 0.0 0.1 0.3 0.4 7.2 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 4.7 0.0 29.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 6.8 412.3 0.0 0.0 0.0 0.0 4.1 9.5 0.8 0.0 0.3 0.1 1.8 1.0 0.0 0.5 0.0 7.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 22.7 0.2 6.6 1.3 6.3 0.4 0.1 0.4 0.4 0.0 0.8 0.2 0.0 0.1 GBP7 "FLJ38822, GBP4L" ENSG00000213512 "Guanylate binding protein 7" Q8N8V2 1 89131742-89176009 "Predicted intracellular proteins" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 156 "liver: 100.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 4.7;Hepatic stellate cells: 5.7;Hepatocytes: 16.3;Theca cells: 4.1" "Cancer enriched" "Detected in single" 58 "liver cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051245 Uncertain NA NA "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "HPA051245: AB_2681404" "unprognostic (4.22e-5)" "unprognostic (7.32e-2)" "unprognostic (6.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.63e-1)" "unprognostic (3.66e-3)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (2.80e-1)" "unprognostic (8.79e-2)" "unprognostic (1.57e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (8.15e-2)" "unprognostic (1.57e-1)" "unprognostic (6.35e-2)" 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 100.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 1.3 0.8 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.6 1.5 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.2 0.1 4.7 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.2 0.0 0.3 5.7 16.3 0.9 0.0 0.8 0.0 0.0 0.8 0.0 0.1 0.6 0.7 0.0 1.9 0.5 3.0 3.1 0.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.3 0.6 0.0 0.4 0.0 0.0 0.0 1.1 4.1 0.0 0.7 GCKR ENSG00000084734 "Glucokinase regulator" 2 27496839-27523684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 136.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 96.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.4;Hep G2: 20.7;HUVEC TERT2: 6.4;TIME: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034098, HPA045855, HPA052227" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "CAB034098: AB_2247323, HPA045855: , HPA052227: " "unprognostic (3.31e-1)" "unprognostic (2.11e-3)" "unprognostic (2.27e-1)" "unprognostic (6.97e-2)" "unprognostic (1.68e-2)" "unprognostic (5.70e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (1.02e-7)" "unprognostic (6.51e-2)" "unprognostic (1.18e-1)" "unprognostic (9.27e-3)" "unprognostic (1.50e-2)" 0.8 7.1 0.8 0.2 1.3 0.9 0.6 4.7 1.6 0.5 1.4 0.1 0.7 0.5 0.6 1.5 0.2 2.3 0.4 1.0 1.3 0.5 136.4 0.2 0.6 1.7 1.2 5.8 1.8 0.2 0.4 0.2 1.6 0.5 0.3 0.9 0.4 0.2 0.3 0.8 0.2 0.3 0.3 1.6 6.5 2.7 1.1 0.2 0.1 0.1 0.3 0.3 0.4 1.4 0.2 0.4 0.4 0.2 0.3 0.2 0.1 0.0 0.1 0.3 0.0 0.4 0.1 0.2 0.5 0.7 0.2 0.2 0.2 0.0 0.0 0.1 0.0 13.4 0.7 20.7 0.8 0.0 0.4 0.3 1.0 0.5 0.1 2.2 6.4 0.1 0.0 0.2 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.5 0.2 4.2 0.1 0.3 0.6 0.2 0.4 0.1 0.2 1.2 0.1 0.2 0.8 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.4 0.3 0.0 0.1 0.0 0.2 0.8 1.3 4.7 1.6 1.0 1.3 1.7 1.2 1.6 0.3 1.1 1.4 0.3 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 7.9 0.1 0.6 0.6 0.0 0.0 2.0 10.4 0.0 0.2 18.3 0.1 0.0 0.1 0.7 96.5 0.1 0.0 1.6 0.0 0.0 2.1 0.0 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 13.7 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 1.7 0.2 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 275.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 183.0;Proximal enterocytes: 105.2;Proximal tubular cells: 83.0" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" 14.8 8.3 1.0 4.5 0.9 6.7 9.3 0.5 1.5 2.9 0.9 11.4 22.4 3.2 0.6 3.8 2.7 2.2 4.4 0.9 1.2 24.9 275.1 4.2 4.6 1.4 0.9 2.4 5.9 2.5 2.9 2.2 1.2 3.7 3.6 0.6 3.1 1.0 3.6 1.9 21.7 1.6 0.4 8.9 8.5 2.3 1.2 2.3 4.1 1.0 3.2 3.3 2.5 1.2 2.9 5.8 3.4 1.2 15.7 2.4 1.8 2.4 2.6 4.6 3.9 12.1 2.4 6.7 1.6 2.7 3.7 1.6 1.7 7.8 0.8 2.0 1.8 9.3 7.5 16.2 1.7 2.8 5.0 2.4 3.5 7.6 3.2 2.1 10.2 5.2 2.4 4.5 3.6 1.9 5.9 2.7 1.5 14.2 4.2 1.9 2.5 11.1 5.8 3.9 1.9 1.9 2.6 1.4 3.0 1.0 3.2 1.7 3.8 3.5 4.1 2.4 6.1 5.1 3.9 5.4 2.7 4.9 2.2 2.2 5.2 6.6 5.6 2.8 2.6 4.4 4.2 4.9 5.6 2.6 3.3 4.3 4.4 3.6 3.5 3.4 6.6 3.7 1.0 0.9 0.5 1.5 0.9 1.2 1.4 0.9 1.2 0.4 1.2 1.2 5.4 6.4 3.2 0.7 8.2 0.4 3.2 4.1 1.8 1.6 2.1 1.4 1.6 18.6 3.0 9.2 0.0 7.9 9.2 18.4 19.6 5.4 0.3 4.4 2.7 8.3 23.4 26.5 0.6 6.2 5.3 2.9 27.0 8.6 1.3 3.4 14.6 183.0 13.2 0.0 0.4 15.8 2.0 16.6 2.4 0.0 1.2 9.1 3.6 1.0 7.7 1.2 9.2 0.5 0.7 4.0 40.6 0.0 13.5 2.8 105.2 83.0 2.4 1.5 0.0 2.7 2.7 1.8 8.3 2.1 1.3 11.1 9.3 7.7 24.9 4.3 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 263.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 373.2;Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 182.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 340000 "Cluster 18: Basophils - Vesicular transport" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 13.9 34.7 11.1 9.7 12.5 9.3 23.2 13.2 16.3 12.7 10.5 21.9 22.5 10.8 22.1 26.9 14.9 11.9 14.3 10.5 12.3 24.5 263.1 7.8 13.5 12.6 11.7 6.5 20.1 26.4 13.3 11.2 12.8 21.1 21.7 5.1 24.1 9.6 47.4 22.1 15.6 7.9 12.3 12.1 18.9 57.8 11.9 14.0 19.5 37.3 17.4 11.9 13.8 14.0 18.8 39.0 27.6 19.9 17.1 23.9 45.8 11.4 11.9 21.6 30.9 13.0 45.2 43.5 14.9 13.6 13.4 24.1 18.9 22.5 20.7 23.2 21.0 20.8 13.3 26.9 26.3 7.8 15.8 22.1 24.0 12.4 20.8 12.0 18.6 24.7 17.5 37.0 14.5 182.1 12.2 16.4 8.2 64.1 30.3 20.2 29.5 34.2 32.5 24.0 30.2 26.2 26.0 49.1 35.6 15.5 81.2 11.1 13.8 17.0 52.5 18.9 8.6 28.2 32.7 35.2 41.9 11.3 20.8 13.4 15.5 9.9 2.6 22.2 2.4 8.2 4.6 3.7 20.7 10.4 3.9 3.1 1.6 5.1 20.1 15.0 7.9 7.4 11.1 12.5 13.2 16.3 10.5 12.3 12.6 11.7 12.8 12.3 11.9 14.0 6.1 6.4 9.6 6.5 13.5 13.4 19.8 26.2 15.9 7.3 36.1 34.2 13.0 47.1 19.0 9.2 4.2 91.4 7.5 34.9 46.9 45.0 125.8 19.4 15.6 11.1 28.8 30.3 2.9 68.0 62.5 15.0 33.1 27.0 3.8 25.7 15.4 373.2 44.6 16.8 3.3 45.7 20.3 38.1 10.9 398.1 11.8 19.0 17.8 3.7 30.4 26.4 4.1 2.0 9.2 41.8 37.4 6.0 13.2 19.8 72.9 77.8 15.0 11.9 0.0 12.3 13.2 51.3 29.4 38.0 14.1 76.2 6.7 55.8 50.3 30.3 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 437.3" "Group enriched" "Detected in some" 5 "Cholangiocytes: 124.4;Hepatocytes: 221.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 64.7;RPTEC TERT1: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" NA NA 20200000000 4400000000 "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.9 0.0 0.0 3.1 2.9 1.7 0.0 2.2 36.0 3.8 0.1 0.0 14.2 437.3 0.8 0.0 0.0 0.0 0.0 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.1 12.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 64.7 0.0 0.0 0.1 0.0 50.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.3 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 124.4 0.0 1.8 0.0 0.0 0.0 0.0 3.9 31.4 0.5 10.8 0.8 0.4 0.0 5.3 1.0 3.9 0.0 0.0 17.9 6.5 0.0 0.0 5.3 221.4 1.0 0.0 0.0 0.2 0.0 5.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 12.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 HAO1 "GOX, GOX1" ENSG00000101323 "Hydroxyacid oxidase 1" Q9UJM8 20 7882985-7940458 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 583 "liver: 607.8" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 301.4" "Cancer enriched" "Detected in some" 184 "liver cancer: 93.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049552, HPA072442" Enhanced NA NA 240000 "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA049552: AB_2680814, HPA072442: " "unprognostic (4.88e-2)" "unprognostic (2.87e-3)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 607.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 301.4 0.0 0.0 0.1 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "liver: 217.1" "Group enriched" "Detected in some" 5 "Early spermatids: 85.6;Hepatocytes: 72.0;Late spermatids: 165.9" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA058279, HPA059076" Enhanced "Secreted to blood" NA NA 7590000 9300000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 1.5 0.0 2.3 0.0 0.1 2.2 2.6 0.5 0.7 0.2 0.0 0.2 0.2 0.0 0.3 0.0 0.1 1.3 0.6 0.6 217.1 0.1 0.0 0.9 0.6 0.1 0.1 0.0 0.7 0.0 0.9 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 3.8 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 2.2 2.6 1.3 0.6 0.9 0.6 0.9 0.5 0.8 0.6 0.1 0.0 0.0 1.3 0.2 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 85.6 0.5 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.4 0.0 4.4 2.2 72.0 0.0 3.3 3.9 0.0 0.0 3.2 0.0 165.9 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.3 0.0 0.0 1.2 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 21.5 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5433.2" "Cell type enriched" "Detected in some" 29 "Hepatocytes: 479.7" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.7;RH-30: 3.0;SiHa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" NA NA 120000000000 28000000000 "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.4 5433.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 3.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.6 0.0 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 479.7 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 116.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 85.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.9;U-266/70: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040692, HPA040948" Supported "Secreted to blood" NA NA 14700000000 26000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" 0.3 0.2 0.5 0.3 0.9 0.4 0.4 1.4 0.8 0.5 0.9 0.6 0.3 0.2 0.1 0.1 0.7 1.6 0.2 0.3 0.1 1.0 116.7 0.8 0.0 0.7 0.4 0.7 2.5 0.0 0.7 0.0 0.8 0.5 0.1 0.2 0.8 0.1 0.5 0.9 0.6 0.0 0.4 0.3 11.0 1.9 0.4 0.9 0.9 0.0 0.0 0.4 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.0 1.7 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 1.4 0.8 0.3 0.1 0.7 0.4 0.8 0.4 0.4 1.8 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.2 0.0 0.5 0.9 0.6 1.6 14.3 0.2 0.0 6.2 0.0 0.0 0.6 0.0 2.7 1.1 0.4 0.0 0.2 0.0 0.0 0.5 0.6 0.0 0.4 8.2 0.1 0.0 0.2 2.9 85.2 0.0 0.0 0.6 14.6 0.0 1.3 0.3 1.7 0.0 0.0 1.8 0.0 0.0 0.3 1.0 0.0 0.7 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.2 0.1 0.4 0.4 0.0 0.3 0.0 0.2 0.1 0.7 0.1 INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "liver: 165.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Hepatocytes: 5.7;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;Karpas-707: 6.3;RH-30: 2.8;U-266/70: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" NA NA 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 165.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 0.0 6.4 0.0 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.6 0.0 6.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 2.8 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.7 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 668 "liver: 2156.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 489.6" "Cancer enriched" "Detected in many" 279 "liver cancer: 626.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 453 "Hep G2: 1103.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 32000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA059150: AB_2683930" "unprognostic (4.82e-2)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.10e-8)" "unprognostic (9.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (4.46e-4)" 0.1 0.2 0.3 0.1 1.1 0.1 3.0 1.6 3.2 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.1 0.6 1.0 0.8 2156.1 0.6 0.1 0.6 0.5 0.0 0.2 0.0 1.7 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.4 0.0 0.0 0.9 0.3 0.5 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 1103.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.1 0.7 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 1.6 3.2 0.6 1.0 0.6 0.5 0.6 0.9 0.9 0.7 0.1 0.0 2.2 0.7 1.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.4 117.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.1 0.0 0.0 0.6 0.0 2.7 3.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 8.2 489.6 0.1 0.0 1.4 0.0 0.0 9.4 0.0 2.1 0.0 0.0 0.0 18.7 0.0 0.0 0.0 1.5 1.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 328.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 280.5" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SCLC-21H: 2.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 28900000000 5300000000 "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.6 1.8 5.9 0.3 6.5 0.0 0.6 6.0 7.6 1.4 9.3 2.3 2.8 0.6 1.0 0.4 1.3 2.5 2.6 6.3 6.2 7.7 328.4 1.0 0.7 7.0 6.5 0.7 4.8 1.0 3.6 0.2 6.4 1.7 1.4 13.1 0.7 0.6 2.4 0.3 2.6 0.6 6.1 2.4 0.8 2.0 6.0 0.4 1.9 1.8 0.4 1.5 0.9 6.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.5 6.0 7.6 6.3 6.2 7.0 6.5 6.4 6.1 6.0 6.3 0.1 0.0 0.0 48.3 0.7 0.0 0.1 0.2 0.6 5.1 0.3 0.5 4.3 14.3 0.1 1.8 16.7 0.0 0.5 0.6 0.0 1.8 2.8 0.6 0.2 1.0 3.0 2.7 10.2 0.5 0.0 0.4 0.0 0.4 0.0 0.2 5.7 280.5 0.2 0.0 15.6 0.4 0.0 4.4 0.0 2.2 0.6 0.3 0.0 6.5 0.1 10.6 2.1 8.0 7.7 0.4 1.4 0.0 0.1 0.0 2.6 1.6 1.1 5.1 0.0 0.6 0.3 1.3 1.3 0.1 0.0 0.0 0.6 0.1 0.7 0.1 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LEAP2 LEAP-2 ENSG00000164406 "Liver enriched antimicrobial peptide 2" Q969E1 5 132873444-132875046 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 532.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1650.6" "Cancer enriched" "Detected in many" 17 "liver cancer: 40.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 3.4;Hep G2: 4.7;U-266/84: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 790000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.14e-2)" "unprognostic (8.78e-2)" "unprognostic (4.75e-1)" "unprognostic (2.16e-1)" "unprognostic (2.82e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-3)" "unprognostic (6.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.62e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (3.97e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.68e-4)" 0.9 0.9 0.9 0.3 0.8 0.5 1.0 2.3 1.2 1.3 0.4 1.7 12.3 0.8 0.2 1.3 1.2 4.5 1.2 0.8 0.8 11.9 532.0 1.1 0.5 0.8 0.7 1.2 1.9 0.7 1.1 0.2 1.0 2.4 1.6 1.0 1.3 0.2 1.4 1.4 23.4 0.1 0.6 2.2 2.0 1.1 0.8 0.3 1.9 0.5 0.5 7.8 1.6 1.8 0.1 0.7 0.4 1.5 0.6 0.4 0.4 0.1 0.1 0.4 0.6 3.4 0.5 0.2 0.1 0.1 0.4 0.7 1.4 0.6 0.0 1.2 1.0 0.3 1.2 4.7 0.1 0.5 0.2 0.1 0.5 0.0 0.1 0.3 0.1 1.1 0.5 0.4 0.0 0.3 0.8 0.6 1.1 1.1 0.5 0.0 0.2 1.1 0.0 0.2 0.5 0.3 0.3 0.7 0.5 0.4 0.8 0.4 0.0 0.2 0.3 0.6 0.1 1.1 3.8 1.1 0.0 0.7 0.2 1.3 0.7 0.3 0.6 0.4 0.8 1.0 0.6 0.7 0.6 0.8 1.0 0.8 1.7 1.0 0.3 0.8 1.1 0.3 0.9 0.8 2.3 1.2 0.8 0.8 0.8 0.7 1.0 0.6 0.8 1.8 2.5 0.0 2.6 1.3 7.9 10.1 10.8 4.1 2.8 17.1 4.9 2.8 1.9 64.3 2.6 0.0 33.3 3.3 7.6 39.2 9.8 2.9 6.2 4.8 3.8 5.2 4.8 9.3 1.1 9.8 7.9 5.8 1.5 10.3 7.0 6.7 14.3 1650.6 1.4 13.5 1.4 12.1 0.0 17.3 14.1 0.5 1.5 4.2 5.4 1.0 2.2 5.2 13.4 2.0 1.8 2.9 30.9 1.9 3.1 14.0 279.9 51.8 1.7 25.2 0.0 13.5 4.8 7.0 2.9 1.4 7.7 7.3 6.2 4.1 8.0 10.2 LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 477.9" "Group enriched" "Detected in some" 15 "Early spermatids: 147.7;Hepatocytes: 100.7;Late spermatids: 55.8" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Region enhanced" "Detected in some" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" NA NA 26500000 5300000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" 0.2 0.5 0.4 0.4 0.8 2.4 0.4 6.3 2.8 0.1 0.0 0.2 0.5 0.3 0.8 0.4 0.1 0.4 0.1 0.9 0.0 0.6 477.9 0.3 0.9 0.0 0.0 0.3 0.1 0.2 0.0 0.2 0.1 0.4 0.2 3.1 0.7 0.2 2.1 1.4 0.9 0.1 0.0 0.9 0.3 8.8 0.0 0.2 0.4 0.0 0.2 0.1 0.0 1.1 0.3 0.4 0.5 0.7 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.8 0.6 0.3 0.3 0.5 0.0 0.2 0.0 0.3 1.0 0.7 0.7 1.3 0.3 1.0 0.1 0.2 0.1 0.3 0.3 0.6 0.1 0.8 0.2 0.3 0.6 0.0 0.4 0.4 0.5 0.3 0.6 0.5 0.5 0.2 0.2 0.9 0.3 0.6 0.0 0.2 0.0 0.9 0.1 0.5 0.8 0.3 0.4 0.4 0.1 1.1 0.5 0.3 0.3 0.9 0.8 0.6 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.8 6.3 2.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.7 0.0 0.1 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 100.7 0.0 0.0 0.1 0.0 0.0 2.9 0.0 55.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569844 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 171.0" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 161.7" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;NK-cells: 1.5;T-cells: 1.8" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;EFO-21: 6.1;Hep G2: 24.4;HMC-1: 6.8;MOLT-4: 5.5;U-2197: 18.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 5500000 "Cluster 10: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" 0.4 0.1 0.5 0.3 0.5 0.2 1.5 0.8 0.9 0.4 0.0 0.6 1.8 0.2 0.9 0.6 1.0 0.8 0.5 0.6 0.3 6.0 171.0 0.3 0.7 0.8 0.7 0.8 2.5 0.0 1.5 0.4 1.0 0.1 0.8 0.1 0.2 0.9 0.0 0.6 0.8 0.1 0.6 0.8 0.5 0.1 0.4 2.1 1.2 0.3 0.2 1.6 0.3 1.2 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.1 0.8 0.0 0.0 8.5 0.0 0.0 6.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 24.4 0.5 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.2 0.1 5.5 0.8 0.0 0.1 0.0 1.1 0.3 0.0 2.6 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 18.4 0.0 0.1 0.0 0.1 0.2 0.5 0.0 1.6 0.1 0.0 1.3 0.1 1.8 0.0 0.3 0.9 0.1 0.0 0.4 1.3 0.2 1.5 0.2 0.0 0.9 1.1 0.5 0.5 0.8 0.9 0.6 0.3 0.8 0.7 1.0 0.6 0.4 1.2 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.8 11.5 0.7 3.7 0.0 0.0 0.9 1.2 5.9 7.8 0.0 0.4 0.5 1.2 0.0 2.7 6.1 3.7 0.1 2.9 0.5 2.7 0.0 0.2 4.2 161.7 0.1 0.0 4.3 0.0 0.0 3.8 0.8 0.1 0.3 0.3 1.8 16.9 0.6 0.0 3.1 0.0 12.9 0.2 0.0 0.0 0.0 0.2 0.3 15.7 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.3 0.6 0.0 1.1 1.2 0.0 0.1 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "liver: 476.5" "Cell type enriched" "Detected in some" 52 "Hepatocytes: 658.6" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 9 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" NA NA 340000000 820000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 2.1 1.2 0.0 1.7 0.0 7.4 2.2 6.4 0.7 2.4 0.0 2.7 1.6 2.8 0.0 1.2 2.7 1.2 1.3 0.1 0.0 1.0 476.5 1.8 2.7 0.0 0.0 2.9 2.9 0.0 2.3 0.6 0.2 1.6 0.0 6.9 2.5 0.0 5.1 5.3 3.4 0.0 0.0 2.5 2.4 1.5 0.0 0.0 1.9 0.0 0.0 2.1 1.6 0.4 0.5 0.3 2.6 1.6 0.0 0.1 0.4 0.7 0.0 0.0 0.0 1.2 1.0 2.3 0.6 0.0 0.5 0.7 0.0 0.0 0.0 0.6 2.3 1.3 2.7 16.4 0.0 2.0 1.5 0.0 0.0 0.1 0.0 1.8 0.0 1.7 0.7 0.5 0.0 0.5 0.6 1.1 0.3 0.2 0.7 1.6 0.9 0.6 0.0 1.3 1.7 0.7 0.9 0.4 0.4 1.6 0.6 1.2 1.2 0.9 0.5 0.8 0.5 0.5 0.9 1.5 0.5 1.7 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 4.6 1.1 0.9 0.2 0.0 0.6 0.2 0.2 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.9 0.0 5.3 9.5 0.0 0.0 0.1 0.0 0.1 1.3 0.0 8.2 658.6 0.1 0.0 8.3 0.0 0.0 12.6 0.3 0.0 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.0 10.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 0.4 0.0 0.7 0.2 0.0 0.0 0.4 0.6 0.0 0.8 0.1 0.0 0.1 MAT1A "MAT, MATA1, SAMS, SAMS1" ENSG00000151224 "Methionine adenosyltransferase 1A" Q00266 10 80271820-80289658 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "liver: 1346.5" "Cell type enriched" "Detected in some" 55 "Hepatocytes: 5534.4" "Cancer enriched" "Detected in many" 54 "liver cancer: 209.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "Hep G2: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048627 Supported NA NA 1900000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA048627: AB_2680465" "unprognostic (6.92e-2)" "unprognostic (2.63e-1)" "unprognostic (2.88e-2)" "unprognostic (9.43e-2)" "unprognostic (3.79e-2)" "unprognostic (2.49e-2)" "unprognostic (2.03e-3)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.66e-2)" "unprognostic (1.11e-16)" "unprognostic (8.59e-3)" "unprognostic (9.90e-2)" "unprognostic (3.58e-1)" "unprognostic (5.98e-2)" 0.5 0.5 0.4 0.1 0.8 0.0 0.4 0.1 0.5 0.2 0.9 0.2 0.2 0.1 57.5 0.1 1.2 0.0 0.2 0.2 0.2 0.9 1346.5 0.4 0.1 0.6 0.8 6.3 43.8 0.1 0.8 0.1 0.4 0.0 0.0 0.0 0.3 1.9 0.0 4.2 0.0 0.2 0.8 0.5 0.2 3.7 0.2 0.4 0.4 0.0 0.0 0.5 0.1 0.2 6.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.3 0.0 3.2 0.1 0.0 0.0 0.0 0.3 0.5 1.6 0.0 94.9 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.1 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 1.0 0.2 0.0 0.5 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.5 0.2 0.2 0.6 0.8 0.4 0.8 0.2 0.2 0.0 0.0 0.5 0.0 8.8 2.0 0.1 0.4 0.0 0.0 0.2 0.6 0.7 67.2 0.9 1.8 0.0 0.0 0.0 0.0 1.9 0.1 23.9 3.0 0.0 5.3 0.0 69.5 0.1 4.6 0.0 0.0 0.0 0.2 0.0 7.6 76.8 5534.4 0.1 0.0 0.0 0.0 0.0 100.4 0.6 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 0.0 0.1 0.0 0.6 10.2 0.0 0.0 0.0 0.2 2.7 0.3 0.0 2.7 0.0 6.0 1.0 0.0 0.0 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 21.9 19.8 8.0 4.6 8.2 5.0 19.0 9.6 12.7 9.9 6.9 12.0 13.7 9.0 10.3 10.1 9.4 7.0 19.0 8.0 9.2 53.1 253.4 17.8 6.4 8.7 9.3 8.6 32.8 26.3 21.5 8.3 9.1 19.5 6.4 5.9 13.6 5.5 20.2 6.2 14.5 6.2 8.8 14.9 19.5 12.1 8.7 10.6 15.9 11.1 10.8 12.4 9.9 9.1 12.6 35.8 5.0 2.6 15.8 12.0 11.9 8.8 13.0 16.4 10.5 34.5 22.4 15.1 25.1 15.5 15.0 19.5 31.9 10.7 15.4 14.7 28.4 14.8 22.9 39.8 25.3 7.8 0.8 17.5 27.8 8.1 23.0 19.6 7.4 16.0 28.8 12.0 17.4 36.0 10.2 36.1 15.6 51.4 17.0 10.8 17.2 25.8 35.1 34.3 8.9 4.8 25.1 14.2 43.8 20.0 17.3 13.0 3.3 5.7 11.1 3.6 7.1 6.8 20.2 17.8 3.3 25.9 6.2 17.5 25.7 73.5 9.4 35.3 12.4 13.5 13.7 12.9 12.3 11.1 16.5 12.6 134.1 17.8 49.1 13.3 15.7 19.1 8.0 8.2 9.6 12.7 8.0 9.2 8.7 9.3 9.1 8.8 8.7 9.1 11.3 19.2 44.0 0.0 20.7 10.7 9.9 63.0 35.9 0.0 25.5 32.5 0.7 58.6 34.3 22.0 0.0 68.1 10.1 10.0 64.6 55.8 2.2 11.9 7.8 10.5 17.6 36.6 0.0 75.7 37.1 13.5 39.8 11.0 8.8 7.2 21.8 205.5 45.7 0.0 0.0 18.7 24.4 22.1 34.8 3.8 13.7 29.3 21.4 0.0 150.8 0.0 35.0 0.0 0.0 75.3 35.9 15.8 13.3 13.3 101.7 201.6 29.9 0.0 13.1 8.4 10.5 6.7 8.5 21.1 8.1 253.8 22.2 9.2 24.9 7.7 NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192589-36242279 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "liver: 328.0" "Group enriched" "Detected in many" 5 "Astrocytes: 105.4;Early spermatids: 324.5;Hepatocytes: 211.9;Late spermatids: 154.9" "Cancer enhanced" "Detected in all" "liver cancer: 36.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced Supported Mitochondria NA NA 30000 "Cluster 24: B-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: AB_2684538" "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" 13.6 20.1 26.6 9.3 23.3 10.6 15.4 21.9 24.2 13.7 14.0 13.9 16.6 13.3 7.9 10.4 12.7 11.9 20.2 22.2 27.1 23.2 328.0 8.4 9.5 25.4 27.4 19.6 26.9 10.7 5.5 16.9 25.3 19.0 13.8 11.2 13.0 16.2 29.4 6.6 12.9 14.2 31.0 8.6 17.1 18.2 25.3 10.3 17.3 29.8 11.4 27.9 8.8 30.3 21.5 14.6 22.4 23.5 32.2 27.2 27.5 19.5 13.2 17.5 13.2 41.4 27.4 74.3 14.0 23.3 23.0 14.9 20.0 14.3 24.2 21.2 16.3 22.0 43.1 23.9 22.7 46.5 8.0 28.9 22.5 21.6 29.9 22.4 18.4 30.2 52.0 27.8 18.0 9.0 42.3 18.2 10.7 18.1 19.2 40.2 51.6 15.8 24.2 18.2 8.7 20.1 102.0 32.4 10.5 16.7 22.9 39.8 15.1 34.1 18.2 27.0 23.9 23.7 30.3 23.2 14.5 57.2 14.2 8.2 1.2 1.1 1.3 1.4 1.8 1.3 1.9 1.5 2.3 5.3 1.6 1.4 0.1 6.7 3.3 1.2 2.1 1.4 26.6 23.3 21.9 24.2 22.2 27.1 25.4 27.4 25.3 31.0 25.3 30.3 9.6 3.2 6.9 105.4 7.5 6.8 6.8 5.4 6.2 5.7 18.3 11.2 29.3 25.8 7.1 5.5 8.4 9.2 9.6 7.4 25.4 5.0 324.5 6.1 9.4 6.8 7.2 13.7 23.8 9.5 8.9 12.5 5.6 7.1 1.3 10.0 12.1 211.9 8.9 3.3 18.3 11.7 4.1 10.4 9.6 154.9 19.9 6.4 14.2 11.2 3.7 16.9 5.2 21.1 23.6 6.9 8.8 23.0 14.3 14.9 6.6 23.1 7.2 5.4 0.0 11.6 13.5 35.1 11.0 7.7 5.7 7.3 6.9 26.4 11.6 12.3 NR1I3 "CAR, CAR1, MB67" ENSG00000143257 "Nuclear receptor subfamily 1 group I member 3" Q14994 1 161229666-161238244 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 169.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 134.8;Proximal tubular cells: 47.1" "Cancer enriched" "Detected in single" 67 "liver cancer: 17.6" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051365 Approved Nucleoplasm NA NA "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA051365: AB_2616454" "unprognostic (2.59e-3)" "unprognostic (1.06e-2)" "unprognostic (9.33e-2)" "unprognostic (6.92e-4)" "unprognostic (2.55e-1)" "unprognostic (1.88e-2)" "unprognostic (1.91e-2)" "unprognostic (5.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.85e-1)" "unprognostic (6.23e-2)" "unprognostic (5.63e-3)" "unprognostic (2.71e-1)" "unprognostic (5.79e-2)" "unprognostic (6.44e-2)" "unprognostic (5.48e-3)" "unprognostic (2.62e-2)" 0.1 0.1 0.2 0.0 2.2 0.6 0.0 0.4 1.0 0.1 0.0 0.1 2.4 0.1 0.0 0.2 0.1 0.0 0.4 0.1 0.0 10.0 169.9 0.2 0.2 0.2 0.1 0.1 0.2 0.0 1.7 0.0 0.3 0.1 0.0 1.0 0.0 0.0 1.5 1.2 3.6 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.1 0.4 0.4 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.8 0.1 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.9 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.2 0.0 0.3 0.1 0.2 0.7 0.7 0.5 0.4 0.3 0.2 0.0 0.7 0.8 0.6 0.1 1.2 0.1 0.5 0.8 0.5 0.8 0.2 0.3 0.6 0.1 0.6 1.0 0.5 0.2 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.4 1.0 0.1 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 22.4 11.7 0.0 1.3 0.6 1.2 0.1 0.0 0.7 0.2 0.1 0.5 5.7 5.0 3.7 0.0 0.1 0.2 0.2 3.9 0.1 1.7 0.1 0.2 2.3 0.0 8.0 0.4 0.0 0.2 1.9 0.0 0.1 13.3 0.1 3.9 134.8 0.3 0.0 0.6 0.0 0.0 4.1 1.1 3.1 0.3 1.8 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.1 0.0 0.4 0.8 0.5 5.0 47.1 4.4 1.6 0.0 2.4 0.5 0.2 0.2 0.0 0.0 0.0 1.6 0.1 0.3 0.9 OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 110.8" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 372.3" "Cancer enriched" "Detected in many" 4 "liver cancer: 4.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 2.3;Hep G2: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 52000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.42e-2)" "unprognostic (6.76e-2)" "unprognostic (7.98e-4)" "unprognostic (9.26e-2)" "unprognostic (9.47e-4)" "unprognostic (3.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.3 0.5 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.3 2.8 0.1 0.0 1.5 110.8 0.3 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 7.8 0.1 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 14.6 0.0 10.7 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 372.3 10.6 0.0 0.0 0.9 0.0 0.0 31.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 163 "liver: 454.4" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 76.3" "Cancer enriched" "Detected in single" 25 "liver cancer: 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.10e-2)" "unprognostic (8.78e-2)" "unprognostic (3.42e-2)" "unprognostic (7.03e-4)" "unprognostic (1.68e-2)" "unprognostic (3.77e-1)" "unprognostic (1.82e-2)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (5.04e-4)" "unprognostic (6.39e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" 0.4 0.8 1.0 0.5 0.7 0.5 0.3 2.0 1.0 0.8 0.2 0.3 0.2 0.6 0.6 0.6 0.7 0.2 0.8 0.9 0.1 0.9 454.4 0.3 0.9 0.2 0.3 0.5 1.3 0.4 0.9 0.4 0.2 0.7 0.3 2.7 0.4 0.4 0.6 1.0 0.5 0.2 0.1 0.9 0.5 1.0 0.2 0.8 0.5 0.5 0.7 0.3 0.2 0.6 0.0 0.1 1.2 0.3 0.4 0.5 0.4 0.6 0.4 0.1 0.2 0.1 0.3 0.7 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.5 1.2 0.0 0.1 0.5 0.2 0.5 0.3 0.1 0.2 1.0 0.4 0.7 0.0 0.1 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.0 0.7 0.2 0.2 0.0 0.3 0.0 0.3 0.2 0.1 0.5 0.4 0.3 0.5 1.2 0.3 0.4 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.0 0.1 0.0 1.0 0.7 2.0 1.0 0.9 0.1 0.2 0.3 0.2 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 76.3 0.1 0.0 0.3 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 531.8" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 440.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" NA NA 96000000000 17000000000 "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 4.1 0.6 0.0 0.5 0.0 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.6 0.2 531.8 0.1 0.0 0.5 0.5 0.6 0.1 0.0 0.8 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.6 5.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.3 0.6 0.6 0.0 0.0 1.5 7.2 1.1 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.6 18.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 3.0 13.5 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.1 8.9 440.0 0.0 0.0 0.2 0.2 0.0 13.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.6 0.5 0.4 0.2 0.0 0.1 0.0 0.6 0.5 0.3 0.1 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 PRAMEF10 ENSG00000187545 "PRAME family member 10" O60809 1 12892896-12898270 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "liver: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 62: Liver - Hemostasis" "unprognostic (1.20e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRAMEF33 PRAMEF33P ENSG00000237700 "PRAME family member 33" A0A0G2JMD5 1 13303539-13308907 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "liver: 1.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 62: Liver - Hemostasis" "unprognostic (6.42e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RDH16 "RODH-4, SDR9C8" ENSG00000139547 "Retinol dehydrogenase 16" O75452 12 56951431-56959374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "liver: 793.0" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 365.1" "Cancer enriched" "Detected in many" 20 "liver cancer: 44.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 4.3;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038518 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "HPA038518: AB_10672713" "unprognostic (5.42e-3)" "unprognostic (4.20e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-2)" "prognostic favorable (2.16e-5)" "unprognostic (8.83e-3)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (6.85e-2)" "unprognostic (6.10e-1)" "unprognostic (7.99e-12)" "unprognostic (2.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" 0.3 0.3 0.9 0.0 0.9 0.0 0.3 0.9 1.1 1.2 0.9 0.3 0.0 0.4 0.1 1.4 0.5 0.0 0.4 0.9 0.8 0.5 793.0 0.4 0.1 0.8 0.8 0.5 0.6 0.0 0.3 0.0 0.9 5.2 0.0 0.4 0.5 2.4 0.2 2.9 0.5 0.0 0.8 2.5 0.3 1.3 0.8 0.2 0.3 0.0 1.3 0.3 1.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.9 1.1 0.9 0.8 0.8 0.8 0.9 0.8 0.8 0.9 0.1 0.0 0.0 2.0 1.9 0.0 1.2 0.3 0.0 2.2 0.2 0.0 2.0 5.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 8.5 0.1 0.1 0.6 0.0 13.5 0.2 0.4 0.0 0.3 0.0 0.1 0.0 0.3 3.6 365.1 0.2 1.7 0.2 0.0 0.0 6.3 0.3 5.8 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.3 5.7 0.0 0.1 0.2 1.0 0.0 0.0 0.1 1.4 0.9 0.8 0.3 0.0 0.6 0.1 0.0 0.3 RTP3 "LTM1, TMEM7, Z3CXXC3" ENSG00000163825 "Receptor transporter protein 3" Q9BQQ7 3 46497976-46500950 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 130 "liver: 119.5" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 89.6" "Cancer enriched" "Detected in some" 5 "liver cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SiHa: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075932 Uncertain Mitochondria NA NA "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA075932: " "unprognostic (2.09e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.11e-6)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.6 119.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 89.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 48144.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 99298.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in some" 5 "midbrain: 3.8;pons: 2.6;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 716.4" "Secreted to blood" NA NA 300000000 11000000000 "Cluster 7: Monocytes - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" 2040.4 54.4 0.1 161.7 0.2 0.0 1382.7 0.1 0.6 258.0 1.8 40.3 1.4 2.2 0.2 51.1 56.6 33.6 23.2 0.3 0.3 29.5 48144.3 98.5 1.1 0.8 3.8 3.3 46.7 0.5 66.6 7.2 2.6 66.5 6.4 0.0 2368.1 4.4 511.6 88.6 75.0 18.8 0.1 38.8 42.0 1.7 6.0 52.1 18.1 0.2 15.7 63.9 29.0 0.1 49.2 0.3 0.0 0.3 34.4 0.2 18.9 1.3 1.1 0.2 0.3 0.1 17.2 0.0 38.3 0.0 11.7 45.5 0.0 716.4 0.3 0.6 0.0 0.8 0.0 0.1 148.4 1.1 0.0 60.9 66.7 0.2 76.7 0.1 0.0 0.0 0.1 0.0 9.3 0.1 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 28.5 0.9 0.0 0.1 4.2 5.5 0.2 0.0 0.5 0.0 0.0 0.2 5.5 0.0 1.3 0.0 1.3 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.3 0.3 0.8 3.8 2.6 0.1 6.0 0.1 107.2 6.4 2.8 0.0 259.8 9.3 64.9 10039.5 10.2 0.0 210.6 1010.4 0.1 1701.5 7604.7 55.2 0.0 1.3 3.0 44.5 0.0 250.4 0.0 12.6 1.6 114.9 1.8 3543.7 0.1 81.1 34.4 8.3 0.0 14.3 2.5 0.0 2568.6 99298.7 1.0 0.0 0.1 5.2 2012.1 2454.9 0.3 0.0 0.0 2.6 51.6 0.0 2.6 0.0 1.0 0.0 0.1 68.8 5.5 0.0 0.1 185.5 3.1 0.2 15716.2 0.0 0.0 31.5 736.1 0.0 0.0 34.1 0.1 2.1 214.7 0.0 36.7 178.8 SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 36265.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 55342.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 150.5" "Group enriched" "Detected in some" 9 "midbrain: 6.3;pons: 4.8;thalamus: 7.7" "Immune cell enhanced" "Detected in some" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 27.8;EFO-21: 20.2;GAMG: 19.6;HaCaT: 25.0;HBEC3-KT: 55.4;HSkMC: 17.6" "Secreted to blood" NA NA 9200000000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-3)" "unprognostic (4.42e-2)" "unprognostic (2.63e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-3)" "unprognostic (7.12e-2)" "unprognostic (7.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.57e-1)" "unprognostic (2.86e-2)" "unprognostic (2.78e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (1.53e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" 562.3 16.9 0.0 137.9 0.1 0.4 321.5 0.5 0.7 277.0 0.6 11.5 0.9 1.0 0.2 22.1 21.1 14.0 8.3 0.1 0.1 12.8 36265.6 35.7 0.6 0.2 6.3 1.7 13.9 0.2 31.1 1.7 4.8 38.5 1.3 0.6 1796.2 1.6 221.2 25.7 21.0 6.5 0.0 20.1 18.1 2.1 7.7 16.3 6.6 0.2 6.8 22.4 7.8 0.7 27.8 0.1 0.2 0.2 1.0 0.0 3.6 0.1 0.8 0.1 0.3 0.0 12.1 0.1 20.2 0.2 19.6 25.0 0.0 55.4 0.1 1.2 0.0 1.0 0.5 0.0 7.8 0.8 0.1 17.6 7.4 0.0 8.9 0.6 0.2 0.0 0.0 0.9 1.5 0.0 0.2 0.0 0.5 0.4 0.0 0.2 0.7 0.0 12.4 1.3 0.3 0.0 1.7 8.5 0.1 0.5 0.4 0.5 0.2 0.2 1.2 0.5 1.2 0.5 0.3 1.7 0.1 1.1 0.3 1.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.1 0.1 1.1 0.1 0.2 0.2 0.2 0.1 0.0 0.1 0.5 0.7 0.1 0.1 0.2 6.3 4.8 0.0 7.7 0.7 7.6 0.0 1.5 0.0 184.4 1.0 5.6 4629.9 0.6 0.0 56.8 68.5 0.2 1052.3 4596.4 3.7 0.0 0.4 0.8 21.9 0.0 70.3 1.6 12.3 0.9 68.2 0.0 2356.0 0.0 34.4 2.3 2.0 0.0 13.5 0.0 0.0 1442.8 55342.6 0.4 0.0 0.0 1.1 1204.4 1502.7 0.0 0.5 0.0 0.6 8.8 0.0 1.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.1 34.5 2.9 0.1 11449.8 0.0 0.0 3.1 400.9 0.3 0.0 5.6 0.1 0.5 144.2 0.0 5.3 65.4 SAA2-SAA4 ENSG00000255071 "SAA2-SAA4 readthrough" 11 18231423-18248635 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "liver: 127.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 20.7" "Cancer enriched" "Detected in many" 13 "liver cancer: 39.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.6;EFO-21: 1.5;GAMG: 1.1;HaCaT: 1.0" HPA060139 Uncertain NA NA "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "HPA060139: AB_2684210" "prognostic favorable (4.56e-4)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.23e-3)" "unprognostic (9.41e-3)" "unprognostic (1.96e-2)" "unprognostic (1.96e-1)" "unprognostic (8.27e-3)" "unprognostic (3.17e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (2.92e-8)" "unprognostic (1.92e-1)" "unprognostic (2.72e-1)" 23.7 1.5 0.0 1.5 0.0 0.0 5.1 0.0 0.3 15.2 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.6 0.0 0.0 0.0 0.2 127.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.5 0.0 0.0 18.8 0.2 5.2 0.4 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.6 0.0 0.0 0.6 0.3 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 20.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 124 "liver: 1943.5" "Group enriched" "Detected in some" 7 "Hepatocytes: 2132.8;Respiratory ciliated cells: 706.8" "Cancer enriched" "Detected in many" 141 "liver cancer: 118.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 28.8" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" NA NA 65000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB026061: , HPA060139: AB_2684210" "unprognostic (4.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-1)" "unprognostic (4.15e-2)" "unprognostic (6.05e-2)" "unprognostic (3.63e-3)" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (1.41e-1)" "unprognostic (7.35e-2)" "unprognostic (2.54e-8)" "unprognostic (2.49e-1)" "unprognostic (6.46e-2)" 7.4 0.5 0.3 0.4 0.3 0.0 6.7 0.3 0.6 15.6 0.3 0.2 0.0 0.0 0.2 0.5 0.5 1.0 0.1 0.3 0.3 0.4 1943.5 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.8 0.0 0.3 1.2 0.0 0.1 11.4 0.1 3.4 0.5 0.1 0.1 0.3 1.2 0.1 1.3 0.4 0.9 0.0 0.0 0.2 0.1 0.1 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.3 0.1 28.8 0.3 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.4 0.5 0.1 0.0 0.0 0.0 2.5 0.0 0.0 184.7 0.0 0.0 2.1 1.4 0.0 18.6 172.6 0.0 0.0 0.0 0.0 3.5 0.0 4.0 0.6 0.4 0.0 1.6 0.0 21.5 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 27.5 2132.8 0.1 0.0 0.0 0.0 71.2 38.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 706.8 0.0 0.0 0.0 23.6 0.1 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.5 SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 490.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 278.7" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 5.3 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 490.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.9 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 4.3 1.8 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 278.7 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.2 SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 776.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 204.5;Hepatocytes: 390.8" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "T-47d: 961.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA017864 Approved "Secreted to blood" NA NA 60800000000 37000000000 "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 1.9 0.0 3.5 0.1 0.5 0.0 0.0 12.6 35.1 0.0 0.0 0.0 43.5 776.6 0.1 0.0 0.0 0.0 0.3 17.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 114.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.4 4.5 0.1 0.4 0.0 0.1 0.7 0.0 0.0 961.9 0.0 0.0 0.5 0.0 0.6 0.0 0.3 0.0 0.5 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 4.4 0.0 0.4 204.5 0.3 0.0 0.0 0.3 0.0 0.4 1.9 33.1 0.0 62.6 0.3 0.4 9.0 16.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 9.7 390.8 0.0 0.0 0.0 0.8 2.0 8.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.0 1.2 0.0 0.0 0.0 0.1 43.0 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.8 0.1 SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 612 "liver: 282.2" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 182.8" "Cancer enriched" "Detected in single" 203 "liver cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 475 "Hep G2: 69.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" NA NA 39800000000 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA002803: AB_1079915" "unprognostic (6.22e-2)" "unprognostic (1.63e-3)" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (2.15e-3)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 282.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 182.8 0.0 0.0 0.0 0.7 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 414.0" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 381.0" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 79 "Hep G2: 58.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" 0.3 2.7 4.8 0.0 7.0 0.0 0.3 4.8 8.0 0.3 2.7 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.1 5.3 7.9 0.7 414.0 0.0 0.2 6.8 6.1 0.6 0.3 0.0 0.8 0.0 5.4 0.0 0.0 1.7 38.0 0.0 0.0 0.1 0.0 0.0 4.8 3.3 0.0 2.3 8.4 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 58.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 7.0 4.8 8.0 5.3 7.9 6.8 6.1 5.4 4.8 8.4 3.9 0.4 0.0 0.0 24.8 4.8 0.5 0.6 0.6 1.2 0.6 0.1 0.1 0.9 7.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 1.9 0.0 24.0 0.3 0.5 0.1 0.4 0.0 0.1 0.0 0.9 16.8 381.0 0.0 0.0 0.2 0.0 0.0 23.2 1.1 0.4 0.6 0.3 0.0 1.9 0.0 7.0 0.0 1.5 0.1 16.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.6 0.0 0.5 0.5 2.4 2.8 1.2 0.4 0.1 1.0 7.8 0.0 0.3 SLC17A2 NPT3 ENSG00000112337 "Solute carrier family 17 member 2" O00624 6 25912754-25930691 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 165 "liver: 79.5" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 30.9" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "Hep G2: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA038270 Uncertain NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA038270: AB_10672511" "prognostic favorable (8.54e-4)" "unprognostic (1.90e-2)" "unprognostic (4.14e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 79.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 30.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC22A1 OCT1 ENSG00000175003 "Solute carrier family 22 member 1" O15245 6 160121815-160158718 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 381 "liver: 609.6" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 966.3" "Cancer enriched" "Detected in some" 81 "liver cancer: 83.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029846 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA029846: AB_10603026" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "unprognostic (7.80e-2)" "unprognostic (2.68e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-2)" "prognostic favorable (1.35e-5)" "unprognostic (2.28e-1)" "unprognostic (8.61e-2)" "unprognostic (3.35e-1)" "unprognostic (9.11e-2)" "unprognostic (9.94e-2)" "unprognostic (1.46e-7)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (4.72e-2)" "unprognostic (8.07e-4)" 0.3 0.3 0.2 0.1 0.1 0.4 0.3 0.0 0.9 0.3 0.3 0.2 0.0 0.3 0.1 0.2 0.3 0.7 0.1 0.5 0.0 0.9 609.6 0.4 0.2 0.1 0.1 0.4 0.4 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.4 0.1 1.0 0.5 0.3 0.0 0.0 1.6 0.3 0.3 0.1 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.4 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.8 0.0 0.0 0.4 0.1 0.4 0.2 0.1 0.2 0.6 0.0 0.3 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.2 0.1 0.0 0.6 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.1 0.4 0.3 0.3 0.7 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.9 0.5 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.2 0.0 1.3 2.0 1.4 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.5 47.1 0.0 0.0 2.1 0.0 0.4 0.1 0.0 0.5 0.3 0.5 0.1 0.9 0.0 13.5 6.1 0.2 0.1 0.2 0.0 0.7 0.0 0.2 11.4 966.3 0.1 0.0 3.7 0.1 0.0 16.3 0.0 0.2 0.3 0.4 0.0 1.0 0.0 0.9 0.0 0.0 0.9 0.1 0.0 0.7 0.1 0.3 0.1 1.8 0.1 0.0 0.0 0.7 0.3 0.0 0.4 0.0 0.3 0.1 1.2 0.3 0.1 0.2 SLC22A9 "FLJ23666, OAT4, OAT7, UST3" ENSG00000149742 "Solute carrier family 22 member 9" Q8IVM8 11 63369785-63410294 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "liver: 46.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 2.7;Excitatory neurons: 5.0;granulocytes: 4.5;Hepatocytes: 15.4" "Cancer enriched" "Detected in single" 166 "liver cancer: 19.3" "Region enhanced" "Detected in some" "cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.45e-1)" "unprognostic (7.24e-2)" "unprognostic (8.86e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.09e-2)" 0.1 0.0 0.5 0.0 0.5 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 1.4 0.0 0.2 46.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.0 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 2.7 5.0 0.2 0.0 0.1 0.0 0.0 4.5 0.1 0.0 15.4 0.0 0.0 0.3 0.0 0.0 0.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 SLC25A47 C14orf68 ENSG00000140107 "Solute carrier family 25 member 47" Q6Q0C1 14 100323339-100330421 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 355 "liver: 534.7" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 270.2" "Cancer enriched" "Detected in single" 273 "liver cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.54e-3)" "unprognostic (2.57e-3)" "unprognostic (5.12e-2)" "unprognostic (2.27e-2)" "unprognostic (6.07e-2)" "unprognostic (1.30e-2)" "unprognostic (4.25e-2)" "unprognostic (1.14e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (1.96e-3)" "unprognostic (4.46e-1)" "unprognostic (1.44e-1)" "unprognostic (4.50e-1)" "unprognostic (5.64e-2)" "unprognostic (1.02e-2)" "unprognostic (1.94e-1)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 534.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.1 0.0 2.7 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.9 270.2 0.0 0.0 0.0 0.6 0.0 6.7 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 3.5 3.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.1 SLC38A4 "ATA3, NAT3, PAAT" ENSG00000139209 "Solute carrier family 38 member 4" Q969I6 12 46764761-46832408 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "liver: 609.9" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 289.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 61.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;LHCN-M2: 43.2;RH-30: 14.6;RT4: 86.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.81e-2)" "unprognostic (7.46e-3)" "unprognostic (5.22e-3)" "unprognostic (1.75e-2)" "unprognostic (3.12e-1)" "unprognostic (1.11e-1)" "prognostic favorable (5.37e-4)" "unprognostic (3.06e-2)" "unprognostic (2.57e-3)" "unprognostic (1.75e-2)" "unprognostic (1.95e-1)" "unprognostic (6.06e-2)" "unprognostic (2.84e-2)" "unprognostic (1.89e-2)" "unprognostic (8.28e-2)" "unprognostic (6.31e-3)" "unprognostic (2.21e-2)" 0.8 1.1 0.2 0.3 0.2 0.0 1.2 0.1 0.4 0.5 0.5 5.1 0.4 2.2 0.2 1.7 0.9 0.3 0.3 0.1 0.6 4.4 609.9 0.3 0.2 0.2 0.3 0.2 6.6 0.2 0.1 2.2 0.1 1.3 1.3 0.1 0.8 0.5 10.2 2.6 0.5 5.4 0.2 1.2 0.2 0.3 0.7 1.4 0.3 2.6 0.8 2.0 0.2 0.3 0.0 0.0 0.1 0.0 17.7 2.2 3.4 2.3 5.6 2.0 1.8 1.1 4.3 0.0 3.5 7.8 0.0 1.0 0.0 0.6 1.7 0.0 0.0 0.1 0.0 0.2 0.7 0.5 0.0 4.2 0.1 0.1 1.4 0.1 0.0 0.0 0.2 0.0 43.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 14.6 0.0 0.0 86.0 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.2 0.5 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.1 0.6 0.2 0.3 0.1 0.2 0.7 0.3 0.1 0.0 0.0 2.6 0.5 0.8 0.0 2.2 3.4 0.0 0.1 0.0 1.5 11.5 0.2 1.8 0.0 2.5 0.0 1.9 0.0 0.0 0.2 0.4 0.2 1.2 0.0 5.3 0.6 0.0 0.7 1.2 0.0 0.2 0.0 1.6 3.9 289.5 0.5 0.0 2.2 0.4 2.0 6.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.2 1.2 0.0 0.0 0.7 0.3 0.4 0.2 0.0 0.0 0.3 0.2 0.0 0.1 2.8 0.6 0.8 0.4 2.7 1.3 0.1 SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 265.1" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 203.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 65.3;A549: 17.5;CAPAN-2: 12.6;GAMG: 13.6;HeLa: 14.2;PC-3: 17.3;U-2 OS: 14.7" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA004943: AB_1854758, HPA050892: AB_2681265" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (7.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.54e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (2.36e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.0 16.2 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.0 0.5 0.0 0.0 265.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 65.3 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.6 0.0 4.3 0.0 13.6 0.1 0.0 0.5 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 14.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 203.4 0.0 0.0 0.5 0.0 0.0 1.6 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.2 TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 128.4" "Group enriched" "Detected in some" 11 "Early spermatids: 61.0;Hepatocytes: 99.9;Late spermatids: 143.9" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Group enriched" "Detected in some" 4 "basal ganglia: 4.4;thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 5.0;SCLC-21H: 8.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.3" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" 0.1 0.1 0.2 0.2 4.4 0.2 0.4 0.1 0.6 0.1 0.0 0.6 2.2 0.1 0.8 0.2 0.5 0.9 0.0 0.2 0.2 0.1 128.4 0.7 0.3 0.2 0.4 0.1 1.3 0.0 13.0 0.7 0.2 0.2 0.5 0.1 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.2 3.6 7.7 1.3 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.2 0.1 5.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.0 0.0 8.1 0.3 0.1 0.6 0.0 0.1 0.1 0.0 0.4 0.3 1.0 0.1 0.0 1.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 0.1 0.6 0.2 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.3 0.5 2.8 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.2 61.0 0.0 0.0 0.3 5.3 8.0 0.1 0.0 2.6 0.0 2.6 0.0 0.0 0.0 2.5 99.9 0.1 0.0 0.1 1.5 0.0 3.2 0.0 143.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.1 0.3 0.3 0.1 0.6 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 883.5" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "RH-30: 4.6" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.9 0.0 0.0 1.3 1273.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 10.7 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 11.7 883.5 0.1 0.0 0.1 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 UROC1 "FLJ31300, HMFN0320" ENSG00000159650 "Urocanate hydratase 1" Q96N76 3 126481166-126517773 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 336 "liver: 116.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 62.2" "Cancer enriched" "Detected in single" 100 "liver cancer: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069863 Enhanced NA NA 670000 "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA069863: AB_2732143" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-2)" "unprognostic (6.43e-2)" "unprognostic (1.43e-1)" "unprognostic (2.23e-3)" "unprognostic (2.95e-1)" "unprognostic (2.57e-2)" "unprognostic (7.71e-2)" "unprognostic (9.97e-2)" "unprognostic (3.04e-1)" "unprognostic (3.65e-5)" "unprognostic (3.97e-2)" "unprognostic (2.66e-1)" "unprognostic (5.52e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 116.6 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 13.5 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 3.3 62.2 0.3 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0