Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABT1 Esf2 ENSG00000146109 "Activator of basal transcription 1" Q9ULW3 6 26596953-26600739 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077039 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA077039: AB_2732328" "unprognostic (1.32e-1)" "unprognostic (3.94e-2)" "unprognostic (3.05e-1)" "unprognostic (1.15e-3)" "unprognostic (1.77e-1)" "unprognostic (7.74e-2)" "unprognostic (2.55e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.30e-3)" "unprognostic (2.93e-2)" "unprognostic (7.25e-3)" "unprognostic (7.20e-2)" "unprognostic (9.57e-2)" "unprognostic (1.49e-1)" "prognostic favorable (3.80e-4)" 9.3 8.0 6.5 9.5 6.7 23.2 9.3 7.8 7.7 8.9 6.5 10.1 10.0 10.8 6.3 13.9 9.2 5.9 8.7 6.5 6.4 8.2 13.0 7.9 15.8 6.4 6.4 9.2 9.4 8.3 7.3 10.7 6.4 8.2 6.7 4.7 9.0 6.7 9.6 14.3 11.6 5.7 6.4 14.8 9.9 8.0 6.6 13.0 7.3 7.1 10.5 9.3 9.7 6.8 23.3 11.9 16.3 28.4 8.9 9.3 23.9 13.4 13.6 20.0 19.5 21.6 10.0 33.8 30.0 11.1 15.9 14.5 19.0 19.5 11.7 18.9 38.7 22.2 11.2 40.6 14.3 30.6 21.7 12.4 17.9 15.9 9.4 9.3 17.5 26.2 39.3 22.1 11.2 23.6 35.6 39.1 16.8 14.9 15.9 21.4 13.2 35.8 12.5 18.7 21.4 17.2 8.3 21.6 32.9 8.6 20.8 24.6 15.1 15.2 11.2 12.2 27.3 25.8 40.9 30.9 7.2 37.6 23.8 76.1 41.6 53.8 66.1 40.2 63.3 66.5 63.8 66.2 39.7 70.2 67.4 60.8 37.2 57.5 41.7 37.1 76.3 88.1 6.5 6.7 7.8 7.7 6.5 6.4 6.4 6.4 6.4 6.4 6.6 6.8 22.4 16.0 15.5 3.3 41.8 59.9 35.8 65.2 34.1 16.2 23.1 22.2 7.1 21.5 31.8 11.0 2.1 96.0 50.8 16.1 41.1 39.4 39.7 12.1 14.0 31.6 34.0 26.9 4.4 38.7 97.5 21.1 16.8 17.3 29.1 17.7 25.4 21.2 42.2 15.2 4.3 25.3 50.8 21.2 22.6 81.8 27.7 22.2 16.0 2.8 32.3 22.0 78.2 3.5 4.5 35.9 19.5 23.7 29.4 31.6 27.9 24.4 21.8 17.2 19.7 15.1 23.4 29.6 41.2 28.3 59.8 109.5 44.3 24.5 29.5 33.6 AC013394.1 ENSG00000279765 "Novel protein" 15 92883413-92949230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "bone marrow: 383.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 18.5;Breast myoepithelial cells: 17.1;dendritic cells: 13.0;Endometrial ciliated cells: 25.9;Endometrial stromal cells: 20.7;Glandular and luminal cells: 35.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (7.26e-3)" "unprognostic (1.34e-1)" "unprognostic (1.53e-3)" "unprognostic (1.42e-1)" "unprognostic (2.84e-2)" "unprognostic (8.97e-2)" "unprognostic (4.62e-2)" "unprognostic (9.34e-2)" "unprognostic (7.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.12e-2)" "unprognostic (2.33e-2)" "unprognostic (1.46e-6)" "unprognostic (2.74e-1)" "unprognostic (3.13e-1)" "unprognostic (2.94e-2)" "unprognostic (3.12e-2)" 34.6 43.5 56.0 36.4 63.4 383.8 82.9 62.5 79.9 49.6 56.2 47.9 35.7 50.9 47.6 40.9 45.2 47.5 37.1 53.0 57.0 56.5 44.8 68.4 65.3 62.7 58.6 60.3 40.4 41.1 0.5 55.4 61.1 56.4 53.0 68.1 50.9 44.9 27.7 47.9 38.9 39.2 60.2 58.4 40.5 36.2 57.0 68.3 93.9 36.4 58.0 42.3 0.2 75.2 31.1 23.9 88.6 57.1 27.0 35.0 64.8 30.1 53.6 47.0 35.1 24.5 70.6 32.8 29.3 39.0 35.6 47.2 37.7 30.8 46.9 0.2 37.0 57.7 48.6 23.6 56.0 30.9 36.8 37.5 44.6 17.4 88.5 68.2 45.0 43.0 60.4 92.5 52.5 33.2 36.3 47.6 77.4 68.2 20.1 50.8 44.5 71.0 66.5 59.3 46.9 53.4 64.4 46.0 115.0 82.6 106.4 69.5 31.5 35.0 27.0 27.4 66.7 67.1 86.0 70.9 27.2 58.5 41.2 10.0 0.9 2.9 2.2 0.7 2.4 4.7 2.5 2.6 0.9 2.8 3.2 2.6 5.7 2.7 1.4 3.0 3.1 0.6 56.0 63.4 62.5 79.9 53.0 57.0 62.7 58.6 61.1 60.2 57.0 75.2 6.9 6.4 11.2 0.0 3.9 0.0 0.0 0.0 0.0 0.0 18.5 17.1 0.0 0.0 3.7 1.8 0.0 2.1 13.0 0.0 3.9 1.2 0.0 25.9 20.7 3.5 0.0 0.0 0.0 1.4 2.3 3.8 0.0 35.4 3.8 12.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 2.0 3.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 3.0 8.0 8.4 0.0 0.0 AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 60.6;Inhibitory neurons: 72.0;Microglial cells: 63.7;Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "prognostic favorable (5.70e-5)" "unprognostic (3.92e-3)" "unprognostic (3.99e-3)" "unprognostic (2.32e-2)" "unprognostic (9.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-3)" "unprognostic (4.91e-3)" "unprognostic (4.96e-2)" "unprognostic (2.58e-1)" "unprognostic (3.96e-1)" "unprognostic (1.58e-2)" 8.8 4.9 7.2 8.8 7.1 20.4 7.7 8.6 7.9 8.4 8.6 9.6 4.7 8.9 6.6 7.3 7.2 6.2 9.9 6.8 6.8 5.0 7.5 11.4 7.0 7.4 7.1 7.0 8.6 6.5 5.8 8.9 7.4 8.1 6.4 18.1 8.4 6.1 13.3 20.1 7.8 9.8 6.8 14.2 9.7 7.3 7.3 7.3 5.5 11.8 6.8 8.2 8.5 7.6 6.0 1.5 11.3 6.5 5.8 6.6 5.7 4.5 4.4 4.6 5.3 0.8 9.0 9.6 6.0 6.6 4.7 2.4 4.9 3.6 4.3 10.7 4.5 4.9 4.2 2.8 5.5 5.6 7.2 4.3 7.6 2.5 3.8 8.8 7.9 11.5 3.7 3.7 6.2 0.9 9.1 6.2 3.7 3.8 2.7 9.0 10.1 1.2 4.5 7.4 5.0 7.3 4.1 3.7 12.7 9.6 3.0 24.6 9.5 3.5 1.7 3.6 3.4 5.4 1.8 1.4 4.3 7.0 3.2 1.3 2.7 3.0 0.8 1.5 1.4 0.6 0.7 1.1 2.0 0.4 0.3 0.4 7.5 0.6 1.4 0.4 0.2 0.8 7.2 7.1 8.6 7.9 6.8 6.8 7.4 7.1 7.4 6.8 7.3 7.6 16.4 19.2 21.7 54.9 6.7 9.8 4.7 5.4 9.6 28.2 8.5 7.1 21.8 12.8 9.2 11.0 22.9 4.2 17.9 5.5 1.9 5.6 2.0 12.7 9.4 11.6 12.6 5.0 60.6 5.6 4.7 7.2 10.7 10.9 2.5 11.4 22.1 11.5 13.5 6.7 72.0 8.4 2.0 42.3 10.0 1.6 5.0 28.9 3.6 63.7 33.6 6.5 6.2 87.4 54.8 14.4 11.7 5.7 4.3 9.0 10.0 1.5 10.3 32.2 19.7 6.8 8.5 11.3 1.6 5.9 12.8 4.1 10.3 3.6 5.7 6.7 AL136295.1 ENSG00000254692 "Novel protein" 14 24189157-24213473 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 6.4;granulocytes: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 8.1" HPA059249 Approved Approved "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.45e-2)" 1.7 3.0 0.6 2.1 0.7 2.0 0.8 0.7 1.5 1.2 0.5 1.3 2.5 1.0 0.2 0.8 1.1 0.4 1.7 0.6 0.8 1.7 0.8 1.1 1.4 0.8 0.6 0.9 1.4 0.5 0.5 0.7 0.7 0.8 0.9 1.3 0.8 0.6 1.9 1.3 2.2 0.6 0.5 0.8 1.3 1.0 0.8 1.6 0.8 0.0 0.4 0.8 0.7 0.7 1.5 1.4 2.4 0.9 2.2 1.3 1.9 1.4 2.0 1.0 2.2 1.0 5.1 1.5 0.2 1.8 2.9 1.5 1.5 0.8 3.2 2.4 0.0 0.9 0.8 1.2 0.4 4.3 2.5 0.5 0.8 1.2 0.0 3.5 0.7 1.3 0.1 4.3 1.7 1.2 1.1 0.0 2.1 0.7 0.0 1.7 1.9 0.0 1.9 1.1 0.2 1.0 8.1 2.7 3.4 2.8 2.0 3.4 4.4 0.2 1.0 1.3 2.1 3.4 2.6 3.6 0.5 0.9 0.8 0.0 0.1 0.5 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.1 0.6 0.7 0.7 1.5 0.6 0.8 0.8 0.6 0.7 0.5 0.8 0.7 0.0 6.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 ALYREF "ALY, ALY/REF, BEF, REF, THOC4" ENSG00000183684 "Aly/REF export factor" 17 81887835-81891586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 148.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016281, HPA019799, HPA061282" Supported Enhanced "Nuclear speckles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "CAB016281: AB_626667, HPA019799: AB_1844788, HPA061282: AB_2684464" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (4.89e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.13e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.77e-2)" "unprognostic (2.26e-1)" "unprognostic (2.55e-3)" "unprognostic (6.58e-2)" "unprognostic (8.07e-2)" "unprognostic (1.74e-3)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" 39.0 30.0 19.2 50.2 19.6 148.9 34.9 20.2 22.9 33.1 17.7 37.4 32.9 35.1 17.1 57.6 31.3 19.6 37.8 19.8 20.0 37.7 29.6 36.0 62.4 19.6 20.7 32.4 26.9 21.3 28.9 32.1 20.9 30.0 24.3 9.4 30.3 15.9 61.5 45.7 34.5 21.1 20.9 44.7 31.6 72.7 19.8 65.7 30.6 21.2 48.8 35.7 36.4 22.1 263.7 237.8 165.5 164.6 34.4 44.8 213.8 130.0 68.0 257.0 161.0 269.4 173.7 291.4 100.8 104.9 155.6 150.5 241.9 137.5 111.7 111.8 425.9 210.8 151.2 295.1 68.6 341.4 183.0 46.1 61.8 155.3 62.0 37.8 155.5 204.6 275.9 175.2 97.2 279.8 721.2 587.2 231.3 152.0 254.2 472.3 206.1 155.1 54.1 152.1 229.8 299.0 123.9 304.8 110.4 89.9 222.1 343.3 103.9 275.1 270.9 130.0 443.2 201.8 107.3 377.6 143.7 217.0 238.2 0.3 1.1 0.1 1.5 1.2 1.0 1.0 1.1 1.0 1.2 1.2 0.3 0.8 0.2 0.9 1.1 2.2 0.6 0.6 19.2 19.6 20.2 22.9 19.8 20.0 19.6 20.7 20.9 20.9 19.8 22.1 68.4 0.0 16.0 1.3 22.9 34.9 22.9 7.5 9.1 11.0 24.7 32.5 13.0 11.5 8.4 20.2 0.0 9.8 59.0 16.1 1.9 5.2 2.3 52.9 49.0 23.4 12.6 43.3 1.7 8.4 23.1 24.9 17.3 53.7 15.2 39.1 8.9 14.8 17.9 5.0 1.7 24.3 6.1 13.9 33.8 3.2 3.4 31.3 14.2 3.7 12.7 21.5 8.2 2.5 5.0 10.5 10.1 4.1 46.4 33.1 7.4 4.3 8.4 7.6 0.0 27.9 30.6 16.5 8.8 22.6 43.0 16.6 27.6 38.2 21.9 31.6 AMD1 SAMDC ENSG00000123505 "Adenosylmethionine decarboxylase 1" P17707 6 110874770-110898879 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Spermidine biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 202.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 70.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029281, HPA029282" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA029281: AB_10600101, HPA029282: AB_10599965" "prognostic unfavorable (3.87e-4)" "unprognostic (4.68e-2)" "unprognostic (1.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.91e-6)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (6.50e-2)" "unprognostic (2.25e-1)" "unprognostic (4.20e-1)" "prognostic favorable (4.28e-4)" "unprognostic (8.62e-3)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (7.71e-2)" 31.8 28.3 35.0 34.7 44.9 89.9 33.9 39.6 56.1 32.8 32.0 36.9 29.2 35.5 25.7 56.0 25.6 33.3 40.2 37.5 38.2 48.6 33.6 33.4 39.9 45.6 38.5 30.0 39.7 40.3 26.0 59.9 42.2 202.9 36.5 35.9 37.4 34.5 26.7 26.9 26.5 35.4 45.5 27.3 31.2 31.9 37.6 40.5 46.2 50.2 50.3 37.4 25.8 67.1 85.8 57.4 68.6 130.6 101.1 63.9 89.8 119.9 131.8 91.4 106.7 92.2 52.3 149.7 56.7 76.7 97.0 57.4 163.9 108.6 125.1 88.5 94.6 155.4 47.5 96.5 60.2 135.7 88.9 43.4 98.0 63.4 126.4 31.8 81.0 75.4 118.2 126.8 156.3 51.8 181.9 103.3 84.7 84.1 51.9 98.5 68.9 89.3 103.9 112.9 87.4 62.2 73.2 91.7 110.7 55.5 59.5 114.9 53.8 60.5 45.7 325.0 131.5 34.4 59.7 152.8 69.6 106.7 79.4 42.9 23.9 37.7 17.4 28.9 20.2 14.5 17.4 20.3 31.5 14.8 20.4 20.8 102.6 15.5 37.3 13.9 22.5 17.0 35.0 44.9 39.6 56.1 37.5 38.2 45.6 38.5 42.2 45.5 37.6 67.1 169.5 38.5 92.5 23.2 164.8 315.3 241.5 49.5 262.4 101.4 178.5 151.1 95.7 125.8 82.7 55.2 60.5 44.5 208.7 144.1 146.8 67.2 31.8 145.0 106.2 104.4 124.4 184.1 39.2 70.0 152.0 132.1 96.4 214.8 93.9 36.9 53.6 59.3 77.0 77.4 37.9 108.2 28.5 109.1 244.2 53.6 43.8 176.7 131.6 23.4 92.0 303.7 60.8 36.7 111.6 87.6 95.9 50.0 118.9 379.4 66.2 89.9 29.3 105.6 19.7 170.5 124.9 93.0 76.7 246.4 288.1 54.6 184.6 45.7 128.8 147.7 ANKRD61 ENSG00000157999 "Ankyrin repeat domain 61" A6NGH8 7 6031376-6036552 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 6.1;testis: 5.6" "Group enriched" "Detected in some" 21 "Early spermatids: 58.5;Late spermatids: 23.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029511, HPA050732" Uncertain Enhanced Nucleoplasm NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA029511: AB_10602430, HPA050732: " "unprognostic (1.40e-1)" "unprognostic (1.03e-3)" "unprognostic (9.32e-2)" "unprognostic (5.67e-2)" "unprognostic (1.73e-1)" "unprognostic (2.56e-2)" "unprognostic (6.76e-2)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.98e-1)" "unprognostic (6.68e-2)" "unprognostic (2.73e-2)" "unprognostic (5.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.55e-2)" "unprognostic (2.63e-1)" 0.4 0.4 0.2 0.6 0.3 6.1 0.5 1.2 0.4 0.4 0.8 0.4 0.5 0.4 0.0 0.3 0.4 0.2 0.4 0.1 0.4 0.2 0.4 0.4 0.8 0.4 0.3 0.5 0.7 0.0 0.4 0.4 0.6 0.3 0.0 0.7 0.6 0.0 0.5 1.2 0.6 0.1 0.1 0.7 0.6 5.6 0.5 0.1 0.6 0.2 0.0 0.3 0.4 1.1 1.4 3.4 1.2 1.7 0.2 0.1 1.6 0.9 0.2 0.3 0.3 1.7 3.5 0.7 0.3 0.1 1.6 1.3 0.6 0.0 0.3 0.2 0.4 1.0 9.3 0.2 0.1 1.0 1.5 0.2 0.7 0.3 0.6 0.8 0.3 1.1 1.2 1.0 0.4 2.3 0.2 1.1 0.6 0.3 0.4 1.0 0.3 0.2 0.3 1.7 0.8 1.5 0.9 1.0 0.1 1.7 1.7 0.6 0.7 1.4 2.9 1.7 1.0 0.9 1.1 0.5 0.4 0.9 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.2 0.4 0.1 0.4 0.4 0.3 0.6 0.1 0.5 1.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 58.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 23.9 0.0 0.2 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 ANP32B "APRIL, PHAPI2, SSP29" ENSG00000136938 "Acidic nuclear phosphoprotein 32 family member B" Q92688 9 97983341-98015943 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063133, HPA067561, HPA069657" Supported Enhanced Nucleoplasm,Centrosome,Cytosol NA NA 570000 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "HPA063133: AB_2684947, HPA067561: AB_2685861, HPA069657: " "unprognostic (2.82e-1)" "unprognostic (2.05e-2)" "unprognostic (4.57e-2)" "unprognostic (6.74e-2)" "unprognostic (1.85e-1)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.98e-7)" "unprognostic (6.76e-3)" "unprognostic (5.70e-2)" "unprognostic (7.16e-2)" "unprognostic (3.50e-1)" "unprognostic (6.39e-2)" "unprognostic (9.22e-3)" "unprognostic (5.20e-2)" "unprognostic (2.36e-1)" "unprognostic (3.67e-2)" "unprognostic (1.78e-2)" 144.0 77.1 134.8 124.0 155.9 365.7 138.6 134.0 187.6 161.6 112.0 145.5 95.1 116.2 104.7 140.9 127.2 60.4 92.3 113.7 150.0 100.2 103.5 122.4 222.6 171.4 149.8 168.5 156.4 68.7 68.1 110.5 158.5 98.6 118.7 46.2 110.6 71.4 109.6 148.0 127.3 78.0 155.6 123.8 131.9 59.6 142.6 271.5 96.9 50.6 248.4 132.5 146.6 173.4 659.7 347.4 378.6 318.4 208.1 365.2 344.4 332.6 292.4 349.2 291.9 438.3 313.1 798.2 194.2 224.6 266.3 423.9 516.1 375.2 397.1 523.0 290.9 692.4 289.1 478.4 266.9 1201.9 386.8 278.7 268.8 280.9 574.0 283.2 307.9 701.5 1359.2 548.8 272.6 875.7 913.5 1062.0 148.2 638.8 341.2 537.8 589.5 381.7 228.8 269.9 304.2 265.8 390.4 376.2 364.5 185.3 213.2 444.0 377.0 226.5 367.3 288.3 355.5 493.2 601.3 469.1 209.7 472.7 432.1 91.3 83.6 118.8 65.2 95.5 89.3 106.1 122.5 92.8 100.5 93.0 143.8 112.1 34.2 74.1 149.7 96.4 162.5 85.3 134.8 155.9 134.0 187.6 113.7 150.0 171.4 149.8 158.5 155.6 142.6 173.4 127.9 86.6 101.8 7.8 227.7 180.7 201.3 180.0 208.9 61.1 100.4 126.0 85.8 112.9 120.7 75.4 25.0 345.5 159.5 159.1 97.8 144.9 114.9 73.8 176.3 146.9 149.9 709.4 5.8 171.6 537.9 121.9 123.3 117.5 119.7 247.9 159.5 96.6 284.7 119.5 6.2 242.2 75.3 310.6 152.0 95.2 146.3 222.5 128.1 14.0 263.5 68.9 149.3 8.0 18.8 137.1 151.1 145.2 266.5 260.6 177.7 101.9 56.3 42.1 151.2 113.4 189.4 204.3 339.0 243.0 154.1 333.1 217.6 188.9 302.7 234.1 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 337.7" "Cell type enhanced" "Detected in many" "Adipocytes: 322.7;Alveolar cells type 1: 589.7;Ductal cells: 434.5;Exocrine glandular cells: 305.3;Pancreatic endocrine cells: 754.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 320 "neutrophil: 207.7" "Lineage enriched" "Detected in single" 327 "granulocytes: 207.7" "Cell line enhanced" "Detected in many" "A-431: 419.5;CACO-2: 403.5;CAPAN-2: 563.7;EFO-21: 334.7;hTERT-HME1: 566.3;OE19: 502.1;RPTEC TERT1: 477.8" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 52.9 3.1 16.5 22.7 17.3 337.7 43.8 14.5 28.2 19.6 11.7 27.7 15.8 12.5 3.7 55.2 16.8 17.3 51.2 14.2 21.6 24.9 3.9 144.4 2.4 19.9 16.1 2.5 32.7 34.0 5.9 81.5 20.8 68.0 26.7 1.6 119.5 12.9 28.3 10.0 13.3 20.1 14.6 21.6 90.5 1.9 19.9 7.1 83.7 36.7 12.7 10.2 15.6 14.7 419.5 77.7 1.3 0.9 1.0 0.9 0.6 4.9 0.4 11.0 10.9 403.5 563.7 0.1 334.7 14.4 0.4 161.6 0.1 300.0 16.0 1.4 3.3 36.4 142.0 23.9 45.9 5.9 0.2 2.4 262.6 4.1 566.3 60.1 118.9 9.0 0.7 0.3 1.9 15.9 1.7 0.2 13.0 502.1 55.4 0.0 0.8 0.0 477.8 45.2 0.3 0.3 235.5 58.2 16.6 186.1 9.9 4.3 153.2 0.6 52.6 0.2 93.0 3.1 5.1 2.2 0.0 0.4 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 207.7 0.1 0.6 0.1 0.0 2.9 16.5 17.3 14.5 28.2 14.2 21.6 19.9 16.1 20.8 14.6 19.9 14.7 322.7 589.7 47.3 0.0 1.1 24.9 81.8 144.9 1.8 0.2 27.6 85.9 8.6 55.8 175.2 38.6 0.0 212.6 1.0 35.4 17.6 434.5 1.1 33.7 4.4 84.6 5.4 3.2 0.9 305.3 106.2 16.9 99.9 58.1 5.1 0.1 23.2 0.6 18.9 0.0 0.3 33.4 122.1 0.3 0.3 0.3 3.1 6.9 5.4 42.2 21.0 1.2 0.0 1.0 0.6 754.2 61.6 0.4 0.6 158.6 11.5 5.5 89.6 0.4 0.0 7.6 18.7 1.1 0.6 21.9 6.7 62.8 2.3 1.3 29.7 46.7 AP001781.2 ENSG00000258529 "Novel protein" 11 111786286-111879425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;HeLa: 3.0" HPA038575 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA038575: AB_10672718" 0.6 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.6 0.0 0.0 0.7 0.7 0.4 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.7 0.0 0.2 0.1 0.3 0.3 1.1 0.1 0.4 0.2 0.2 0.4 0.0 0.0 0.1 0.1 0.0 0.5 0.5 0.0 0.7 0.1 0.8 0.0 0.1 0.0 2.8 0.0 0.1 0.5 0.0 0.8 1.0 0.0 0.0 0.6 0.2 0.0 1.7 3.0 0.2 0.0 0.0 0.3 1.0 1.0 0.7 1.5 0.4 0.0 1.0 0.1 1.0 0.0 0.0 0.6 1.3 0.2 0.0 0.0 0.0 0.0 1.1 0.4 0.9 0.0 0.0 0.7 0.0 0.1 0.0 0.6 0.6 0.0 1.2 0.3 0.5 0.1 0.8 0.7 2.1 0.3 1.5 0.2 0.3 0.5 0.5 1.2 0.6 0.8 0.5 0.7 0.7 0.6 0.6 1.3 0.6 0.0 0.7 0.5 0.7 0.2 1.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AP003108.2 ENSG00000256591 "Novel transcript" 11 61429220-61485822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;dendritic cells: 1.4;Endometrial stromal cells: 1.5;Glandular and luminal cells: 1.4;Granulosa cells: 3.4;Respiratory ciliated cells: 1.5;Theca cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 28.0" "Low region specificity" "Detected in all" HPA039732 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA039732: AB_10962868" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (9.60e-2)" "unprognostic (4.91e-2)" "unprognostic (5.69e-2)" "unprognostic (5.98e-2)" "unprognostic (4.41e-2)" "unprognostic (6.40e-2)" "unprognostic (3.53e-2)" "unprognostic (5.83e-2)" "unprognostic (4.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-7)" "unprognostic (5.74e-2)" "unprognostic (9.69e-2)" "unprognostic (1.40e-1)" "unprognostic (4.66e-3)" 5.1 4.7 2.7 4.0 3.1 8.7 4.0 3.0 3.9 5.9 2.6 2.7 2.2 3.6 3.1 3.4 3.2 4.8 7.0 3.1 3.4 3.6 2.4 3.8 4.6 3.2 3.3 2.1 2.0 2.3 1.3 3.1 3.3 3.3 3.3 1.0 2.6 2.7 1.8 1.7 2.6 4.2 3.0 4.4 3.4 2.9 3.2 7.7 5.1 5.9 4.8 5.4 1.9 3.1 6.8 3.3 3.8 6.1 9.7 8.1 2.0 8.9 7.6 6.6 6.2 2.6 4.5 7.1 14.5 8.3 5.5 3.0 4.5 6.3 3.9 6.3 5.3 5.4 0.9 0.9 11.4 4.2 2.0 15.6 3.8 9.8 7.8 4.2 16.7 9.2 5.8 6.0 10.9 5.3 14.1 4.0 8.5 5.8 4.5 8.4 5.8 8.6 4.4 5.4 3.0 3.8 3.7 3.5 12.6 2.5 4.9 4.8 28.0 8.4 4.7 4.5 5.0 2.2 9.5 4.8 7.2 5.5 6.3 5.9 8.0 8.4 11.6 7.3 14.6 5.9 11.5 11.8 6.3 6.8 13.2 12.3 11.2 7.4 6.8 6.8 12.9 10.2 2.7 3.1 3.0 3.9 3.1 3.4 3.2 3.3 3.3 3.0 3.2 3.1 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.6 3.7 0.0 0.3 1.4 0.0 0.0 0.2 0.0 0.7 1.5 0.6 0.0 0.0 0.0 0.2 0.4 0.3 0.0 1.4 1.3 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.6 1.5 0.0 0.0 AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 44.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: AB_2685550, HPA067880: AB_2685914" "unprognostic (3.64e-1)" "unprognostic (9.40e-2)" "unprognostic (4.37e-3)" "unprognostic (1.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.03e-2)" "unprognostic (2.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" 8.3 4.8 3.2 6.9 2.6 44.0 6.6 5.8 3.6 5.4 1.3 6.0 5.7 7.1 2.0 10.2 5.2 3.1 5.0 3.6 1.2 5.7 5.8 8.7 4.7 3.9 1.5 2.9 10.3 6.4 3.5 3.8 3.0 5.0 3.0 2.5 7.0 4.5 9.6 9.1 6.8 3.2 1.1 10.0 6.0 2.5 1.8 4.8 4.9 3.4 4.3 6.6 5.1 1.6 12.8 9.8 2.8 14.3 8.6 4.1 16.4 5.3 6.2 6.1 4.7 7.7 6.0 7.8 9.4 6.3 12.4 15.8 8.7 4.3 2.9 12.1 10.1 7.0 12.0 3.8 5.8 9.9 13.3 7.0 10.1 4.0 2.9 6.0 5.2 13.6 15.6 9.7 3.6 9.2 5.5 10.5 4.6 4.4 10.1 17.3 0.5 16.8 5.9 15.8 2.7 5.4 4.1 2.6 26.0 3.7 4.4 14.1 7.6 10.2 8.6 13.6 6.0 10.0 11.2 8.1 7.5 8.5 10.5 1.1 1.7 0.6 0.5 1.0 0.2 0.3 0.2 0.2 0.5 0.3 0.3 0.2 25.0 0.4 1.3 0.3 0.2 0.8 3.2 2.6 5.8 3.6 3.6 1.2 3.9 1.5 3.0 1.1 1.8 1.6 2.0 0.0 8.8 6.2 3.9 2.4 12.3 4.3 7.4 5.0 4.2 2.0 1.6 2.8 3.7 7.3 14.6 7.6 5.9 12.8 1.9 8.9 1.4 6.3 2.9 3.0 3.0 0.0 3.6 13.6 18.2 2.9 6.6 10.7 2.5 5.3 1.4 7.1 14.0 11.8 3.2 3.8 6.1 12.4 2.1 0.7 0.6 11.6 7.2 3.7 17.8 3.0 6.2 1.0 2.2 9.4 6.9 3.8 3.6 5.6 10.1 8.8 2.9 8.0 0.0 3.7 3.0 0.6 4.7 6.0 2.3 34.9 4.3 2.0 4.5 10.0 ARID4A "RBBP1, RBP-1, RBP1" ENSG00000032219 "AT-rich interaction domain 4A" P29374 14 58298504-58373887 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048899 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "HPA048899: " "unprognostic (1.57e-1)" "unprognostic (9.39e-2)" "unprognostic (5.17e-2)" "unprognostic (2.69e-1)" "unprognostic (3.70e-2)" "prognostic favorable (1.91e-4)" "unprognostic (2.71e-1)" "prognostic favorable (7.82e-4)" "unprognostic (2.08e-2)" "unprognostic (6.92e-2)" "unprognostic (3.27e-1)" "unprognostic (3.72e-2)" "unprognostic (9.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (4.11e-2)" "unprognostic (3.52e-2)" 9.8 6.9 8.6 11.1 9.2 34.7 9.1 14.8 10.0 8.6 8.9 7.7 8.8 9.5 6.8 7.4 6.8 9.0 8.7 8.0 11.7 9.4 18.7 10.3 14.9 7.9 7.7 12.5 7.4 9.8 5.4 9.8 7.6 8.6 8.8 14.0 6.7 7.6 5.4 8.7 9.1 8.2 6.8 14.0 8.9 6.9 12.3 14.5 10.6 6.3 11.2 8.4 7.5 10.7 8.5 7.0 19.2 9.5 9.3 11.2 9.7 9.9 8.4 6.6 10.4 8.3 13.1 20.4 10.3 8.4 6.3 9.6 8.6 4.8 9.6 14.3 5.5 9.2 8.2 8.0 5.6 19.7 12.8 8.4 5.2 6.4 6.6 10.5 10.6 11.6 10.7 16.3 7.1 11.5 14.3 17.7 3.8 8.2 8.7 14.5 16.6 6.1 7.1 14.9 16.5 14.3 16.9 8.4 12.0 9.4 14.3 17.8 15.3 11.2 8.7 9.1 4.6 5.3 4.2 18.3 6.7 12.3 5.8 65.8 19.5 59.1 20.6 20.1 23.3 31.5 25.3 22.1 14.9 42.3 27.0 26.5 109.4 29.1 40.8 19.8 19.8 10.1 8.6 9.2 14.8 10.0 8.0 11.7 7.9 7.7 7.6 6.8 12.3 10.7 57.7 83.3 100.9 68.9 73.5 38.4 21.2 22.1 64.3 111.0 29.5 35.8 55.0 24.3 32.3 27.6 52.1 19.9 74.0 33.0 19.6 23.3 18.2 40.5 37.6 47.1 22.8 45.8 94.2 21.7 21.3 40.1 26.0 52.6 65.2 39.9 37.5 41.9 34.7 112.7 78.6 35.5 20.3 47.7 49.5 8.8 36.4 59.3 26.6 63.7 75.8 63.9 49.4 86.5 91.4 24.9 38.6 36.1 55.1 20.9 43.4 14.9 11.2 64.2 19.7 40.0 43.0 38.6 33.8 55.4 33.4 20.4 77.0 34.1 32.9 17.7 ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717893-152762396 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 214.0;eosinophil: 161.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 214.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear membrane" Cytosol "HPA014743: AB_1845030" "unprognostic (4.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "unprognostic (9.86e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (5.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.14e-1)" "unprognostic (2.67e-1)" "unprognostic (4.57e-1)" "unprognostic (7.39e-2)" 5.1 3.9 3.0 1.8 4.0 8.3 4.7 3.2 3.0 4.4 2.2 3.7 2.4 4.2 1.2 6.0 3.8 1.2 2.7 2.6 3.1 2.5 1.9 4.0 3.4 3.9 3.3 5.0 2.7 1.1 3.1 4.4 4.3 3.1 1.9 3.2 3.9 1.8 3.5 7.1 3.5 1.6 3.6 4.4 3.1 5.3 3.3 3.9 3.2 2.0 2.4 4.2 5.5 5.3 9.6 6.2 13.7 3.9 4.1 4.6 19.7 11.6 4.9 9.6 12.2 14.2 13.3 17.2 10.6 5.2 4.3 10.7 8.1 5.7 10.4 26.1 15.1 14.2 5.3 13.0 4.5 12.1 12.4 3.3 6.5 10.6 8.9 3.4 7.5 11.9 14.9 10.6 7.8 7.1 12.1 12.6 13.3 3.2 12.7 13.0 13.4 13.9 4.5 7.2 11.6 12.0 10.4 1.1 9.7 4.7 4.7 7.9 10.0 14.4 9.9 10.2 10.3 9.9 10.3 13.1 6.8 10.4 12.3 214.0 9.1 161.8 13.2 10.2 13.2 20.3 13.3 13.5 10.9 18.4 13.6 11.4 24.8 9.7 12.8 24.8 19.7 13.2 3.0 4.0 3.2 3.0 2.6 3.1 3.9 3.3 4.3 3.6 3.3 5.3 34.3 16.0 10.0 30.7 41.9 106.6 48.5 74.0 50.7 6.3 20.3 14.9 4.3 17.2 29.9 11.0 4.2 155.7 42.4 14.1 17.6 24.9 14.1 17.7 20.0 31.3 13.8 81.0 21.0 18.6 136.2 27.9 30.1 25.0 27.3 19.4 28.5 5.9 39.8 8.4 23.8 22.2 38.7 24.2 57.2 24.2 19.6 33.6 46.2 30.9 46.2 19.8 32.0 38.7 56.8 22.5 18.6 17.0 33.8 40.3 16.3 8.8 29.2 15.8 32.9 22.2 24.9 24.4 30.0 43.4 106.6 108.4 45.2 27.9 24.5 51.3 ARMC8 "DKFZP434A043, GID5, HSPC056, VID28" ENSG00000114098 "Armadillo repeat containing 8" Q8IUR7 3 138187248-138298384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036996, HPA044869" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Vesicles, Cytosol" "HPA036996: AB_10672786, HPA044869: AB_2679123" "unprognostic (2.04e-1)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (3.51e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (8.90e-5)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (7.48e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (3.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.06e-2)" "unprognostic (5.51e-2)" "unprognostic (1.18e-1)" 20.8 14.3 14.6 18.0 16.6 60.6 16.4 41.2 18.5 14.7 25.6 16.8 12.0 17.6 12.2 21.0 15.7 15.3 17.4 13.3 16.9 18.9 16.9 16.3 21.2 16.0 15.8 16.0 14.2 21.3 12.3 19.8 17.5 16.5 18.3 26.2 12.5 17.5 38.7 12.8 13.5 24.4 15.9 15.9 15.4 18.4 16.7 22.2 21.3 34.8 22.9 22.2 13.4 19.4 46.2 22.0 28.5 23.2 35.2 30.7 37.9 34.8 33.4 46.7 45.3 34.3 23.7 43.2 35.0 30.2 54.6 23.5 37.1 33.9 57.4 29.3 25.7 77.2 14.3 23.9 44.3 60.6 82.5 46.2 21.2 30.0 42.9 25.4 37.0 37.0 29.3 23.8 58.6 40.5 42.7 28.6 39.2 34.8 19.1 33.0 45.7 34.6 30.7 42.3 33.0 24.0 50.0 17.2 29.1 36.8 33.8 31.6 40.4 24.8 20.2 33.1 25.9 45.0 37.5 65.2 22.4 28.4 25.2 79.7 39.7 74.8 38.6 43.5 44.6 48.8 35.2 41.1 45.9 43.3 41.1 40.6 27.9 48.8 46.0 20.3 50.4 37.4 14.6 16.6 41.2 18.5 13.3 16.9 16.0 15.8 17.5 15.9 16.7 19.4 25.0 28.9 14.1 56.2 38.2 31.0 31.9 29.0 25.0 34.9 17.7 14.9 23.1 24.3 27.2 12.9 33.3 29.9 35.6 25.1 11.7 20.2 7.3 16.2 22.3 23.4 23.4 59.6 101.9 14.6 27.6 23.4 31.1 19.5 35.4 24.1 24.3 24.6 22.5 43.7 93.6 16.9 30.5 32.7 39.2 7.3 30.4 35.2 19.6 70.3 27.2 25.0 39.1 128.2 120.8 14.8 17.2 22.2 26.8 28.1 17.0 26.1 17.4 47.0 13.1 30.2 31.5 43.4 32.2 22.3 28.4 34.1 30.9 19.6 17.4 28.3 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 ATG14 "ATG14L, KIAA0831" ENSG00000126775 "Autophagy related 14" Q6ZNE5 14 55366391-55411830 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037242 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "CAB037242: AB_1852353" "unprognostic (8.53e-2)" "unprognostic (1.84e-1)" "unprognostic (2.93e-2)" "unprognostic (5.83e-2)" "unprognostic (3.37e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.61e-2)" "unprognostic (3.44e-2)" "unprognostic (2.92e-1)" "unprognostic (2.63e-1)" "unprognostic (8.49e-3)" "prognostic favorable (1.95e-4)" "unprognostic (1.70e-1)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" 6.1 6.7 5.3 4.6 6.6 28.9 6.4 6.9 6.7 7.3 4.8 6.8 5.3 7.7 2.0 7.0 5.6 5.7 8.0 5.7 5.4 6.2 4.8 5.3 4.5 5.8 5.7 8.0 4.9 8.0 3.4 6.2 5.7 5.6 3.8 8.9 6.0 6.5 16.0 8.7 5.0 6.1 5.8 5.6 4.8 7.7 5.8 5.1 6.4 10.4 5.4 6.4 6.6 8.5 8.2 5.7 4.8 7.0 8.3 9.9 10.4 7.5 13.1 7.1 8.5 5.1 9.6 3.2 6.3 7.3 3.6 8.7 5.6 2.9 10.2 5.2 3.7 4.7 7.5 6.7 8.4 5.8 6.4 6.8 8.7 6.0 5.4 11.3 6.7 5.6 4.8 7.1 6.7 6.5 4.0 6.7 8.8 3.6 7.4 4.0 12.3 2.4 3.4 5.3 5.8 6.5 11.2 6.5 7.8 5.7 6.4 2.3 8.0 11.1 8.3 5.6 3.8 4.1 4.7 3.5 6.9 3.2 5.9 2.7 2.5 1.1 2.4 1.8 2.0 2.5 2.4 2.4 1.6 2.8 2.6 2.7 0.8 5.9 1.6 2.4 2.0 1.7 5.3 6.6 6.9 6.7 5.7 5.4 5.8 5.7 5.7 5.8 5.8 8.5 22.5 19.2 27.6 17.3 20.0 17.5 7.3 7.5 30.7 14.9 27.3 22.0 39.1 11.5 15.8 11.0 8.4 10.0 17.3 15.2 19.6 11.6 7.5 21.8 30.0 19.0 19.7 49.9 28.0 7.9 7.8 22.6 12.2 35.1 25.9 16.1 15.7 12.7 7.2 3.3 27.8 10.8 8.2 12.2 9.2 5.8 14.3 14.4 14.2 12.2 14.1 12.6 16.5 24.1 44.5 11.9 12.4 16.6 16.9 9.8 10.3 17.2 10.2 23.1 13.1 22.5 21.2 21.3 53.2 20.8 26.0 14.4 17.2 11.4 8.3 11.2 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 20.6 10.7 4.7 24.9 6.9 70.6 17.4 15.9 7.6 19.1 13.8 26.3 24.3 18.7 14.6 45.4 13.7 21.1 14.1 6.0 6.3 18.0 18.3 16.5 27.9 7.5 6.1 20.5 21.0 29.4 10.3 14.5 7.3 28.3 29.0 30.8 19.4 13.4 11.4 28.2 24.0 19.5 5.6 21.8 51.1 31.6 6.6 44.6 16.8 16.8 28.4 25.7 22.5 15.8 69.7 9.7 20.5 28.7 42.6 46.1 19.3 32.8 41.6 23.2 27.1 23.7 34.0 31.3 53.5 44.0 48.2 40.4 24.6 31.3 40.2 73.9 20.9 76.7 13.1 5.2 24.8 62.3 47.3 31.5 34.7 26.1 37.4 34.1 37.0 48.7 27.7 94.3 37.8 22.9 50.3 19.1 14.5 38.1 19.2 21.2 59.8 37.8 28.1 55.8 12.5 22.0 86.2 10.7 36.9 18.3 11.9 43.7 36.6 35.0 38.7 30.5 56.2 131.0 125.5 58.1 24.1 25.3 20.9 5.5 1.0 4.3 1.7 1.0 1.7 2.1 1.4 1.7 1.1 1.3 1.2 1.8 3.8 1.8 1.0 2.4 1.2 0.8 4.7 6.9 15.9 7.6 6.0 6.3 7.5 6.1 7.3 5.6 6.6 15.8 26.8 16.0 13.2 34.6 27.8 34.3 25.7 15.9 26.2 12.2 13.8 9.7 15.6 18.6 16.5 20.2 14.6 12.8 43.0 44.6 0.0 12.5 34.1 19.0 22.9 15.7 6.7 26.1 81.6 16.5 3.8 19.5 46.4 22.1 11.4 14.0 16.1 16.4 10.4 38.7 64.3 30.5 16.2 19.4 26.4 23.8 19.3 29.3 14.2 45.9 19.9 8.4 27.8 67.8 132.6 25.2 27.0 21.1 55.5 35.8 24.3 7.8 19.8 31.4 19.7 24.1 17.7 18.7 11.4 43.8 44.6 9.6 40.9 7.0 27.3 45.4 ATXN1L BOAT1 ENSG00000224470 "Ataxin 1 like" P0C7T5 16 71845976-71885268 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 263.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062596, HPA062789" Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA062596: AB_2684802, HPA062789: AB_2684868" "unprognostic (1.51e-1)" "unprognostic (1.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (3.01e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (8.13e-2)" "unprognostic (1.99e-1)" "prognostic favorable (5.33e-8)" "unprognostic (1.61e-1)" "unprognostic (1.42e-1)" "unprognostic (5.30e-2)" "prognostic unfavorable (8.42e-4)" 14.0 8.0 11.5 9.9 12.7 39.5 10.9 9.0 9.7 11.1 5.6 10.4 8.2 12.3 7.3 9.7 10.9 9.0 9.5 9.3 9.4 18.7 6.6 12.0 10.0 10.9 11.7 12.7 12.5 16.5 5.2 10.8 10.3 8.1 9.2 8.0 9.4 10.4 10.4 12.1 9.4 12.9 10.3 11.8 10.0 12.2 12.5 12.8 11.9 13.7 10.5 8.9 7.4 11.9 11.8 15.7 15.7 11.5 18.1 8.9 18.4 9.8 10.8 17.4 13.2 22.6 12.9 13.2 15.0 15.4 8.0 20.3 13.4 14.9 18.9 3.6 11.9 9.7 17.7 15.9 13.5 11.9 19.0 12.8 18.6 19.8 14.2 11.4 16.0 17.0 11.1 10.2 10.4 33.6 20.2 11.7 14.3 9.3 7.4 21.4 15.9 15.8 12.1 16.4 8.3 14.2 19.5 10.2 11.9 16.4 16.0 12.5 19.4 19.0 19.9 12.1 13.3 23.0 20.8 30.7 11.8 7.9 16.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.3 0.4 0.2 0.2 0.5 0.5 0.4 0.4 0.2 0.1 0.7 0.3 11.5 12.7 9.0 9.7 9.3 9.4 10.9 11.7 10.3 10.3 12.5 11.9 11.1 0.0 10.6 4.2 14.9 22.8 15.3 11.4 14.2 11.2 16.0 10.2 15.7 14.3 9.5 14.7 14.6 8.3 19.9 15.2 17.6 11.9 44.2 19.1 15.0 14.2 7.8 5.7 6.8 11.8 7.9 11.0 5.6 35.4 12.7 8.0 14.3 12.3 8.5 15.2 5.7 8.7 8.2 14.3 25.2 263.0 14.9 11.8 12.4 5.6 16.9 6.3 29.9 3.5 9.1 14.4 19.6 12.8 16.0 18.3 13.3 15.8 9.9 17.2 13.1 15.5 14.3 22.4 21.1 13.1 24.9 11.5 15.8 8.0 10.6 28.4 ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA034989: AB_10602596" "unprognostic (1.51e-2)" "unprognostic (2.44e-1)" "unprognostic (5.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.22e-4)" "unprognostic (9.65e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-3)" "unprognostic (2.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (3.45e-2)" 7.5 6.3 4.5 11.4 4.1 24.4 7.1 4.9 4.4 7.4 0.2 6.9 8.0 8.6 4.7 8.7 6.3 9.6 5.8 3.1 3.7 7.1 8.4 9.0 12.7 3.4 3.3 8.0 21.0 10.9 2.3 8.3 2.7 6.7 8.8 16.3 7.8 5.2 7.1 9.3 9.2 7.9 0.7 10.6 8.4 15.0 3.1 16.5 7.5 8.7 11.7 7.4 4.4 3.2 8.4 5.7 8.1 7.2 8.5 11.3 9.5 6.5 9.0 11.1 10.5 8.9 8.7 12.5 3.1 9.0 12.5 6.5 9.6 9.1 11.9 22.8 4.9 16.1 10.7 4.2 6.4 8.5 17.7 7.9 9.0 15.7 17.7 9.0 8.4 13.3 6.3 26.2 7.7 25.8 12.7 6.8 5.5 5.7 3.0 9.1 7.1 10.1 6.1 11.0 3.1 5.6 13.2 9.4 10.8 6.4 5.1 12.2 11.9 11.4 12.0 12.7 12.9 12.9 13.2 10.3 10.3 11.6 9.4 15.8 1.1 2.1 3.7 1.0 3.3 1.0 6.2 4.0 0.8 2.4 6.2 4.1 4.5 3.5 0.7 1.5 6.2 1.3 4.5 4.1 4.9 4.4 3.1 3.7 3.4 3.3 2.7 0.7 3.1 3.2 2.4 9.6 9.1 34.6 17.0 43.6 24.9 17.6 29.6 73.2 3.4 1.7 10.5 35.8 17.9 5.5 102.2 14.1 21.5 38.3 0.0 2.8 17.1 3.3 1.5 16.1 26.4 29.5 81.2 4.2 13.6 16.6 18.8 3.5 14.7 1.2 26.7 22.8 14.2 25.2 67.0 19.7 24.4 34.6 30.3 9.5 12.8 20.1 12.4 64.6 33.5 24.5 54.6 60.3 46.7 2.5 28.5 13.2 14.8 26.1 28.1 0.7 27.4 70.8 0.0 39.2 15.6 14.8 15.6 25.6 46.2 61.2 41.5 1.6 20.1 38.6 AZIN1 "OAZI, OAZIN, ODC1L" ENSG00000155096 "Antizyme inhibitor 1" O14977 8 102826308-102893864 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027948 Approved Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" Vesicles "HPA027948: AB_10602391" "unprognostic (1.16e-2)" "unprognostic (4.81e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (8.55e-2)" "unprognostic (3.41e-2)" "unprognostic (7.19e-2)" "unprognostic (1.51e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" 61.7 48.1 45.7 48.1 50.3 141.1 57.8 44.8 51.2 55.3 43.5 49.1 66.6 44.4 30.3 52.7 64.0 43.6 51.5 51.9 50.5 39.4 78.0 40.1 58.1 48.1 48.2 38.7 136.6 38.3 31.6 82.8 48.1 52.5 53.6 57.8 47.7 49.5 41.9 32.7 80.8 44.5 53.8 35.9 52.2 35.7 46.7 58.6 67.5 30.9 60.6 62.3 27.3 60.0 320.4 81.7 129.0 92.6 122.7 83.3 77.6 145.4 168.5 103.5 106.8 87.1 217.5 148.0 111.0 121.9 64.3 119.5 113.8 114.5 165.8 244.7 57.4 147.4 30.1 72.3 156.0 81.0 120.7 58.9 136.1 72.5 182.4 92.2 72.8 86.0 112.6 124.0 165.2 92.6 201.8 59.3 144.9 239.3 123.0 87.3 136.5 84.2 108.2 146.7 208.2 327.3 49.1 100.0 144.3 209.9 131.7 84.7 85.9 83.2 83.9 135.7 118.6 122.3 104.2 207.4 98.3 120.1 117.0 73.3 57.7 68.0 31.2 64.1 36.7 43.7 40.8 29.9 55.9 27.5 33.1 32.1 68.5 40.1 64.5 44.3 50.0 65.7 45.7 50.3 44.8 51.2 51.9 50.5 48.1 48.2 48.1 53.8 46.7 60.0 56.3 60.9 27.7 30.0 59.6 93.8 121.1 52.8 93.4 31.5 64.0 39.8 46.3 28.6 52.8 42.3 37.5 148.7 54.0 48.4 52.8 39.6 62.6 95.1 37.9 34.9 84.9 62.7 35.9 50.5 55.0 55.5 59.1 85.4 68.5 31.9 33.5 65.0 54.7 23.5 31.9 77.3 63.1 72.8 127.2 107.9 49.7 86.0 64.0 23.4 53.0 50.4 32.0 30.2 23.7 66.6 44.0 32.4 97.6 106.7 114.6 52.6 167.6 42.3 19.7 36.0 57.1 34.5 30.7 90.8 82.3 261.9 71.6 26.2 66.0 117.0 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB005029: AB_562051" "unprognostic (3.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (5.67e-2)" "unprognostic (6.58e-3)" "prognostic unfavorable (4.52e-4)" "prognostic unfavorable (5.64e-4)" "unprognostic (2.36e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (6.07e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" 9.4 29.6 10.4 20.7 10.6 27.7 7.5 10.5 13.0 10.4 12.2 32.4 47.0 10.1 9.1 34.0 7.9 10.6 23.2 10.3 9.8 23.9 11.5 13.7 22.0 11.8 10.9 7.2 12.8 13.5 12.0 11.1 11.2 11.2 24.9 3.7 11.9 9.1 18.8 18.7 37.1 13.5 11.0 30.5 21.9 7.8 11.7 19.2 7.7 18.1 23.4 21.8 12.0 10.4 37.6 20.4 21.3 32.2 14.3 14.0 27.1 19.1 15.3 53.7 41.8 42.2 28.7 32.5 32.6 28.1 24.8 38.3 41.0 77.7 23.6 37.7 43.6 20.6 18.8 34.4 36.6 44.5 32.3 23.0 60.7 45.1 52.6 15.7 29.4 28.7 18.9 28.6 20.1 55.0 38.8 29.7 23.7 26.4 50.0 37.0 20.5 59.9 45.6 30.6 26.3 19.6 24.4 77.3 37.1 26.6 25.4 74.5 28.2 28.3 30.0 18.5 24.9 75.4 100.4 27.5 9.6 52.6 31.7 63.5 45.2 85.1 34.7 64.8 39.5 25.3 32.1 34.7 42.8 18.4 17.6 23.2 30.6 22.4 57.3 15.0 56.1 53.2 10.4 10.6 10.5 13.0 10.3 9.8 11.8 10.9 11.2 11.0 11.7 10.4 8.6 3.2 3.4 3.9 24.6 27.1 11.6 15.5 14.2 6.6 10.7 8.3 6.4 11.5 8.0 3.7 8.4 16.3 22.1 75.4 13.7 20.5 4.7 7.2 8.9 10.1 22.1 6.1 4.5 18.7 41.8 7.5 17.9 10.0 11.4 11.1 10.0 6.3 30.2 5.0 3.6 32.5 14.2 21.9 30.2 1.7 7.8 16.9 21.4 2.8 25.8 4.7 12.3 1.0 2.7 27.7 47.9 11.7 54.5 10.4 79.6 9.6 5.6 6.9 13.1 5.6 11.8 0.3 1.0 19.1 21.6 9.9 24.6 25.2 40.6 20.1 BNIP2 "BNIP-2, Nip2" ENSG00000140299 "BCL2 interacting protein 2" Q12982 15 59659146-59689534 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 131.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026843 Approved Supported Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoli "HPA026843: AB_1845403" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "prognostic favorable (8.42e-4)" "unprognostic (6.70e-2)" "unprognostic (4.81e-2)" "unprognostic (2.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.44e-2)" "unprognostic (1.26e-1)" "unprognostic (4.72e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (4.68e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" 49.6 22.4 14.2 41.0 15.8 131.6 30.7 14.7 13.5 28.7 10.6 20.8 16.4 36.9 19.2 30.5 20.5 27.8 47.7 11.9 16.8 19.3 46.5 41.4 48.6 17.2 15.9 31.2 13.9 17.5 10.3 42.7 17.2 26.6 23.2 27.3 20.5 29.4 32.6 20.9 20.3 41.4 16.7 46.5 18.0 22.8 16.2 43.4 18.9 48.8 48.1 41.2 21.2 18.1 39.4 35.9 45.9 37.8 70.8 57.9 40.2 60.3 85.0 54.3 61.9 29.0 18.2 67.9 39.5 87.9 74.4 72.7 48.9 70.1 73.4 49.3 31.1 83.0 52.6 30.8 77.6 107.3 91.7 68.6 71.9 49.4 85.0 51.2 91.1 78.9 48.3 70.8 88.5 22.6 50.5 44.6 41.2 7.7 25.8 55.3 57.5 87.7 56.9 87.3 36.9 50.2 39.5 52.7 104.4 66.4 43.7 112.9 72.2 58.3 71.0 38.0 60.2 52.6 112.7 90.0 46.5 98.1 60.5 50.6 46.6 72.2 29.6 46.9 35.1 31.9 31.1 31.8 43.1 28.9 31.8 32.1 81.5 34.8 40.1 34.5 36.3 43.8 14.2 15.8 14.7 13.5 11.9 16.8 17.2 15.9 17.2 16.7 16.2 18.1 116.7 73.7 44.0 20.2 87.9 86.7 98.8 56.0 70.6 32.5 35.3 29.6 81.9 28.6 43.0 14.7 47.9 64.0 82.6 31.3 37.2 31.5 9.0 41.8 44.5 105.6 15.5 57.7 15.4 26.8 76.8 68.0 46.9 65.8 96.4 31.0 87.8 49.6 91.7 50.5 17.5 24.3 32.6 115.6 106.7 6.1 43.5 125.6 51.6 25.3 120.8 55.3 64.9 20.6 28.2 36.9 22.1 57.2 63.1 75.1 20.0 16.6 45.4 50.2 78.9 56.2 68.1 28.8 32.2 64.4 92.5 193.9 73.5 42.3 19.4 136.8 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRIX1 "BRIX, BXDC2, FLJ11100" ENSG00000113460 "Biogenesis of ribosomes BRX1" Q8TDN6 5 34915677-34925996 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039614 Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Mitotic chromosome" "HPA039614: AB_10963698" "prognostic unfavorable (2.18e-4)" "unprognostic (2.60e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.10e-5)" "unprognostic (1.82e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (4.11e-8)" "unprognostic (3.37e-2)" "unprognostic (3.84e-3)" "prognostic favorable (6.34e-4)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.07e-9)" "unprognostic (1.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (2.09e-2)" 18.6 17.1 13.3 17.6 13.8 37.1 24.7 15.2 18.7 15.1 12.8 15.6 12.9 17.4 17.8 17.7 16.1 12.2 14.7 13.2 14.1 15.1 18.5 13.0 26.4 13.7 13.6 18.5 13.7 18.2 9.5 25.7 13.8 15.7 17.1 11.6 12.9 14.5 10.4 14.6 12.8 16.1 13.9 14.3 13.1 13.9 13.5 20.7 15.8 12.2 25.8 30.1 12.3 15.2 66.1 57.0 64.2 87.1 26.0 37.8 121.6 74.9 52.7 100.0 63.5 74.5 81.0 138.8 38.7 45.5 113.5 52.1 108.5 79.8 117.3 75.1 101.3 93.9 125.7 71.9 67.4 150.8 63.8 44.4 49.8 93.3 85.9 31.0 48.5 72.9 158.4 43.8 66.2 63.6 108.3 163.9 101.0 75.2 86.8 94.6 112.5 60.5 59.3 70.7 75.1 68.8 157.6 109.7 76.1 50.0 66.4 92.7 28.4 78.7 87.5 58.1 151.0 39.3 87.7 177.6 66.3 171.3 100.3 15.0 21.4 10.0 34.5 21.0 50.1 63.7 43.2 44.3 27.8 49.9 53.3 46.6 1.2 43.7 30.6 37.5 43.5 44.6 13.3 13.8 15.2 18.7 13.2 14.1 13.7 13.6 13.8 13.9 13.5 15.2 35.5 28.9 30.7 8.5 40.0 108.7 114.3 110.2 55.2 20.8 27.3 41.3 23.2 25.8 63.0 23.9 12.5 127.1 37.0 13.5 49.0 52.5 24.8 29.9 45.1 40.6 21.0 45.2 11.9 42.7 100.6 44.4 19.4 31.6 20.2 30.0 20.0 11.9 42.7 21.9 13.4 19.0 63.1 10.7 20.1 8.4 39.4 18.4 32.0 4.7 31.1 22.3 21.6 10.6 13.6 44.7 13.1 29.0 21.4 70.9 9.9 37.9 45.8 37.2 6.6 54.3 55.7 59.9 77.6 46.0 95.8 126.1 37.1 31.7 31.9 85.1 BRMS1 DKFZP564A063 ENSG00000174744 "BRMS1 transcriptional repressor and anoikis regulator" Q9HCU9 11 66337333-66345125 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010824, HPA019637" Approved Approved Centrosome NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "CAB010824: , HPA019637: AB_1845448" "unprognostic (1.75e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" "unprognostic (4.31e-2)" "unprognostic (1.72e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (5.67e-3)" "unprognostic (2.54e-1)" "unprognostic (6.32e-2)" "unprognostic (1.61e-1)" 27.2 28.1 25.3 24.1 27.0 52.2 27.1 27.2 28.5 22.0 26.9 28.9 26.0 20.5 17.5 36.7 20.0 18.0 26.0 26.6 25.4 35.0 29.1 25.0 32.2 27.4 27.1 19.9 40.9 19.3 17.9 19.5 26.8 33.9 19.2 9.1 30.5 18.3 38.0 41.5 29.6 13.1 26.5 38.3 31.6 31.5 27.1 28.7 26.5 13.8 25.6 25.1 25.8 28.0 80.3 102.4 33.8 56.6 35.1 36.1 47.8 54.4 58.9 95.9 63.9 84.1 51.2 53.5 78.9 53.8 82.5 91.7 64.9 99.2 45.0 63.9 53.9 49.2 54.2 62.1 65.1 71.3 54.9 41.2 104.5 97.0 72.2 29.1 59.9 60.1 59.0 24.3 58.0 128.9 87.5 169.1 73.3 61.2 95.3 73.2 62.2 100.0 60.1 45.6 70.8 57.0 67.2 68.6 180.9 24.6 83.5 43.7 58.2 71.9 68.2 117.1 68.8 50.2 53.8 85.3 93.0 46.2 78.8 45.6 79.4 80.8 61.1 77.3 65.1 79.2 65.2 58.6 62.4 75.6 56.3 54.3 104.2 51.3 69.9 67.3 79.9 67.3 25.3 27.0 27.2 28.5 26.6 25.4 27.4 27.1 26.8 26.5 27.1 28.0 27.2 16.0 26.9 4.2 42.7 58.1 28.5 45.0 33.6 12.3 31.7 27.6 11.7 40.0 22.6 22.0 6.2 61.5 37.1 109.0 54.8 72.6 7.4 25.6 16.6 30.8 32.3 33.7 2.9 117.9 68.5 22.9 33.1 18.6 27.8 21.4 28.2 21.5 67.6 11.8 2.2 54.0 32.6 51.3 41.7 9.9 22.4 39.1 28.4 5.6 68.3 31.7 56.7 3.0 5.1 85.7 85.6 14.7 30.5 40.6 80.5 51.1 22.2 14.9 6.6 23.1 27.3 35.8 39.4 32.2 60.0 71.7 42.5 21.1 61.3 29.8 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 8.0 7.1 4.7 6.9 6.9 23.5 7.7 9.9 7.4 8.2 3.8 8.3 4.8 9.5 4.4 8.6 8.8 5.5 7.3 6.7 3.8 6.2 5.5 7.9 8.9 4.7 4.2 9.3 7.3 7.7 6.7 6.5 4.3 7.5 4.0 4.0 9.1 5.0 9.5 10.9 8.3 5.4 3.1 10.5 7.5 14.4 5.2 11.9 9.0 6.8 7.6 7.9 7.8 5.5 9.9 17.2 12.5 8.2 8.9 8.6 82.4 12.6 7.5 14.3 10.2 12.1 8.3 18.6 6.0 11.6 13.5 8.2 15.3 12.0 9.0 20.1 17.9 21.4 33.8 9.8 11.4 30.6 20.0 8.5 9.8 19.8 13.1 7.2 10.8 17.5 25.2 15.9 8.3 24.3 19.8 25.7 20.6 6.7 15.9 28.7 10.6 12.3 6.7 14.5 8.9 15.2 12.7 9.0 10.1 8.2 9.8 31.4 14.1 15.9 13.6 14.5 24.0 13.4 18.1 31.5 13.1 25.9 15.1 1.0 0.9 1.4 1.3 0.8 2.0 0.6 0.9 1.2 0.8 0.5 1.1 1.3 0.8 4.2 0.7 1.9 0.7 0.8 4.7 6.9 9.9 7.4 6.7 3.8 4.7 4.2 4.3 3.1 5.2 5.5 7.9 16.0 10.0 2.6 6.8 14.1 5.1 3.9 8.0 4.6 9.2 7.0 3.7 2.8 6.2 7.3 6.2 4.2 13.0 9.4 0.0 4.1 3.9 4.2 6.9 9.7 10.2 9.7 3.4 5.5 5.5 5.8 7.7 7.0 8.8 7.3 11.0 3.5 6.4 8.4 2.4 5.0 2.0 5.6 9.2 1.2 6.5 6.9 1.8 2.8 6.3 5.2 5.2 4.0 2.9 6.1 3.1 6.0 7.9 5.1 4.9 2.1 4.3 5.1 6.6 11.3 7.7 16.6 13.9 9.9 18.5 3.7 10.8 5.6 6.1 6.8 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 BZW1 "BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 3845.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" 130.6 129.1 30.3 97.5 33.0 219.6 88.7 37.7 40.9 65.5 49.2 98.4 64.6 66.6 58.4 120.8 53.4 93.1 56.4 33.9 36.9 88.5 227.0 73.5 97.9 36.5 36.7 62.3 62.6 72.4 30.7 105.2 35.3 99.6 90.6 45.8 61.2 61.7 101.7 47.9 71.4 80.1 39.1 62.8 69.0 170.9 42.1 123.0 74.4 75.2 109.4 164.6 61.4 45.4 296.6 230.1 309.4 187.1 305.2 353.3 221.6 425.2 501.8 281.2 244.5 360.7 195.3 142.5 144.7 339.7 186.1 159.8 284.9 512.6 521.8 154.6 151.3 370.8 453.9 280.1 244.5 420.9 199.6 205.3 233.5 373.2 398.9 244.6 495.4 132.3 328.5 234.0 379.3 236.6 387.9 201.3 392.4 120.1 575.4 293.1 333.4 148.6 256.1 435.2 188.9 218.7 325.5 120.9 226.1 255.5 126.6 216.7 555.0 416.8 242.9 255.2 276.6 286.1 428.6 377.8 341.2 209.3 312.1 236.7 140.7 168.5 177.9 173.4 207.2 102.0 126.0 167.5 162.6 87.1 112.4 156.7 117.0 218.5 195.1 75.5 171.5 294.6 30.3 33.0 37.7 40.9 33.9 36.9 36.5 36.7 35.3 39.1 42.1 45.4 207.3 86.6 108.1 31.3 148.5 198.5 318.5 310.7 125.7 37.1 159.0 89.8 18.1 82.9 290.3 90.1 18.8 115.4 263.2 127.5 138.9 250.2 927.0 108.3 145.3 149.0 96.7 72.8 28.7 233.1 164.3 181.2 72.4 150.0 196.9 72.7 99.2 262.4 114.1 58.9 32.1 113.3 183.1 88.6 194.0 3845.6 102.2 169.1 124.5 15.0 308.1 119.6 170.0 24.6 36.6 464.4 106.5 95.9 132.7 242.3 68.2 163.3 121.7 33.4 98.6 159.4 179.8 175.2 169.2 133.2 196.1 195.2 200.3 103.3 106.1 370.9 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.2;Late spermatids: 76.3;Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" 16.4 18.2 15.2 12.8 15.7 71.9 20.5 18.6 19.7 13.6 14.2 15.1 16.2 15.3 18.4 14.7 14.9 12.3 18.3 15.4 15.2 15.1 16.9 12.2 21.8 15.0 15.0 17.0 23.2 17.9 12.9 14.6 15.0 14.4 13.1 19.2 19.3 12.9 34.1 16.3 15.2 13.0 15.6 18.1 19.8 35.8 15.4 21.9 14.0 26.4 18.8 16.3 12.3 16.5 24.9 17.2 35.3 27.0 25.4 36.2 25.9 34.3 34.9 42.3 44.7 15.8 17.8 22.4 33.7 27.4 26.9 26.2 28.2 28.8 45.7 33.4 30.4 22.5 21.2 35.5 35.3 65.4 26.3 37.9 46.7 38.2 39.3 36.8 37.0 30.6 39.7 34.0 29.4 29.5 42.4 48.0 30.4 11.6 18.9 28.0 30.7 43.0 29.2 29.5 25.5 36.0 25.4 18.8 58.3 32.7 28.2 31.2 24.3 43.3 19.1 15.8 31.0 43.2 41.4 46.0 21.4 37.3 22.1 97.5 28.8 34.2 24.5 30.7 24.2 34.7 25.9 23.2 27.1 30.9 19.8 25.9 28.0 28.8 30.0 26.6 41.5 19.8 15.2 15.7 18.6 19.7 15.4 15.2 15.0 15.0 15.0 15.6 15.4 16.5 9.6 19.2 6.1 3.9 13.7 11.9 8.9 17.4 18.2 9.6 13.1 16.5 12.7 10.0 12.1 1.8 6.2 19.0 23.0 10.4 11.7 20.2 145.2 13.7 14.7 10.8 7.2 12.4 5.5 28.8 32.0 12.4 8.6 14.4 14.0 12.9 10.0 9.6 21.3 8.4 6.0 12.9 16.2 20.1 10.3 76.3 22.4 14.4 12.4 5.6 24.4 13.1 20.6 4.5 5.1 20.0 14.0 17.0 13.5 11.7 17.8 20.1 5.1 12.1 0.0 14.1 11.3 124.0 35.9 12.8 12.4 13.1 13.6 17.3 15.9 9.3 C18orf25 "Ark2N, ARKL1, MGC12909, RNF111L1" ENSG00000152242 "Chromosome 18 open reading frame 25" Q96B23 18 46173553-46266992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051314, HPA051899" Approved Approved Nucleoplasm,Cytosol No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA051314: AB_2681438, HPA051899: AB_2681657" "unprognostic (1.44e-2)" "unprognostic (2.32e-1)" "unprognostic (2.08e-2)" "unprognostic (5.77e-3)" "unprognostic (4.46e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.97e-1)" "unprognostic (7.46e-2)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" "unprognostic (5.80e-2)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" 8.5 6.9 9.0 8.9 8.9 34.1 10.4 12.3 10.3 11.9 18.1 8.1 7.7 9.2 7.9 37.5 9.6 6.5 15.8 8.0 8.2 8.8 8.1 9.6 12.1 10.2 12.9 9.2 6.0 18.8 6.2 8.2 11.2 8.3 9.2 27.6 13.3 7.5 23.3 13.2 8.9 9.4 7.4 11.1 8.7 12.0 10.2 15.0 11.9 16.0 15.4 9.8 16.4 9.1 18.4 17.9 14.8 16.9 10.4 9.3 19.0 26.0 13.8 27.3 23.1 13.9 20.5 14.0 24.1 17.7 9.8 40.9 27.7 17.7 29.5 23.5 8.9 12.4 16.0 10.6 17.9 23.5 16.0 8.7 20.2 31.9 26.3 15.9 11.0 12.9 14.1 16.3 15.3 13.7 17.9 11.9 13.2 6.3 7.0 16.0 17.6 20.7 26.1 32.5 20.7 10.8 19.1 13.4 13.7 17.9 8.8 14.3 16.0 24.7 17.6 6.0 24.3 21.3 19.7 22.3 12.8 24.4 27.0 4.9 8.9 18.6 6.3 9.9 11.2 6.9 12.3 9.6 8.8 9.0 8.6 6.8 22.7 3.5 14.3 12.6 8.7 6.9 9.0 8.9 12.3 10.3 8.0 8.2 10.2 12.9 11.2 7.4 10.2 9.1 18.4 12.8 9.1 16.0 19.2 25.2 10.4 11.5 11.4 14.5 13.4 9.9 30.4 5.7 9.5 14.7 20.9 8.1 26.1 15.1 1.9 9.1 2.4 42.1 14.4 16.2 12.0 16.8 62.5 6.5 10.5 12.1 13.7 39.2 15.2 9.9 11.7 13.0 9.1 13.5 45.2 10.0 6.1 13.1 18.0 3.5 8.1 12.9 7.2 22.5 11.1 12.4 9.2 25.6 25.9 20.4 10.1 10.5 16.5 13.0 9.2 7.6 16.9 30.6 19.7 14.8 11.8 20.6 14.9 14.2 31.8 24.4 18.6 6.6 10.1 23.3 C3orf38 MGC26717 ENSG00000179021 "Chromosome 3 open reading frame 38" Q5JPI3 3 88149959-88168729 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 341.2;Late spermatids: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 147.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034736, HPA034737" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA034736: AB_2674307, HPA034737: AB_10671505" "unprognostic (1.93e-1)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (1.48e-2)" "unprognostic (1.74e-2)" "unprognostic (2.41e-2)" "unprognostic (2.26e-3)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "prognostic favorable (3.55e-4)" "unprognostic (9.28e-3)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.95e-2)" "unprognostic (2.88e-3)" "unprognostic (1.63e-1)" "unprognostic (4.57e-2)" "unprognostic (3.67e-2)" 10.2 8.8 7.1 11.1 9.2 42.1 12.4 11.2 11.5 10.7 6.8 11.1 9.7 9.1 10.9 12.1 10.6 9.7 9.9 7.8 8.6 10.4 14.1 10.1 17.7 8.0 7.5 11.6 7.8 10.7 4.8 12.4 8.6 10.1 11.0 7.7 8.8 9.5 8.0 8.2 10.0 10.9 8.7 13.2 10.4 32.8 7.8 20.9 12.0 10.8 18.4 12.5 5.2 12.8 16.6 17.4 32.5 17.7 22.5 19.8 15.0 26.3 31.5 38.6 51.9 19.5 22.5 22.8 23.1 24.5 18.4 11.8 23.7 19.2 33.1 40.1 11.7 27.1 12.3 16.9 30.8 37.9 22.5 27.7 20.1 26.1 21.8 25.2 23.1 23.7 18.0 25.1 43.4 19.4 38.3 16.9 40.0 31.0 18.8 23.9 11.4 21.5 25.7 22.6 10.1 14.6 24.1 14.2 42.2 26.2 25.5 30.0 20.6 24.2 25.7 147.7 29.8 22.6 36.2 33.0 18.8 29.8 23.0 47.8 22.3 24.1 16.8 32.4 21.4 26.0 15.3 17.2 23.5 22.3 15.1 15.6 9.7 23.4 27.4 16.2 20.5 21.6 7.1 9.2 11.2 11.5 7.8 8.6 8.0 7.5 8.6 8.7 7.8 12.8 13.3 19.2 7.5 5.9 30.9 11.7 18.8 19.9 14.2 21.6 11.0 9.5 6.9 8.6 16.7 5.5 22.9 21.6 24.4 13.9 19.6 16.7 341.2 14.4 13.3 10.8 16.2 23.5 9.7 13.7 22.7 17.3 11.7 10.2 14.0 14.2 11.4 7.5 26.7 6.7 9.1 13.3 14.2 23.9 25.1 312.0 16.4 24.0 16.0 6.5 28.0 23.2 23.7 10.1 15.0 15.3 19.3 15.1 17.5 18.6 16.1 14.5 21.2 24.8 13.1 14.9 16.6 75.7 12.2 14.9 14.1 25.6 24.6 18.1 11.1 22.5 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB012175: , HPA050678: AB_2681214" "unprognostic (6.96e-2)" "prognostic favorable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.3 6.6 6.0 13.9 6.7 40.2 10.5 7.8 6.7 11.8 6.7 11.1 10.7 10.2 9.6 15.3 10.3 7.0 8.4 5.9 6.2 9.1 6.4 10.4 22.0 7.2 6.4 9.3 8.4 11.1 5.3 12.4 7.7 7.6 12.7 7.7 11.9 6.3 3.9 17.4 15.4 9.4 5.9 19.0 9.6 9.1 6.9 27.5 8.8 5.0 27.1 7.5 11.2 10.0 27.5 25.4 28.8 51.0 15.1 17.5 15.4 27.7 13.0 25.4 27.8 26.0 31.3 52.0 25.9 18.4 19.4 27.3 29.4 22.6 34.0 45.8 22.5 31.2 40.4 18.3 8.4 60.7 37.4 13.0 18.1 31.0 11.0 11.3 22.0 41.3 26.3 32.6 27.5 27.5 109.1 64.4 36.5 27.4 26.3 79.1 14.6 32.6 15.1 23.3 31.5 34.2 54.8 24.3 17.3 19.6 26.3 23.4 24.1 22.5 15.5 40.7 28.1 27.0 28.5 59.4 24.9 72.6 41.1 69.2 17.9 17.2 24.5 21.7 24.2 25.7 33.3 25.3 17.3 28.8 24.3 28.3 21.7 24.2 34.1 21.1 38.9 15.3 6.0 6.7 7.8 6.7 5.9 6.2 7.2 6.4 7.7 5.9 6.9 10.0 14.1 9.6 8.3 4.2 17.4 15.2 7.0 9.4 6.2 4.8 19.0 13.5 6.2 17.2 7.0 7.3 8.4 20.0 19.3 8.7 3.9 8.1 36.6 10.8 17.9 16.4 10.7 9.7 11.2 7.7 14.6 9.3 8.2 20.1 10.1 22.7 18.2 7.2 10.1 6.7 8.8 11.5 0.0 16.9 23.3 51.0 11.8 12.2 21.4 4.7 20.8 4.4 13.4 4.5 22.4 9.4 5.9 8.2 13.0 5.8 9.1 4.2 4.9 15.4 0.0 8.3 10.9 13.7 25.9 16.1 13.8 5.7 16.7 9.3 15.5 7.0 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743949-107761667 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 11.2 8.1 3.1 12.5 5.3 40.0 15.1 7.8 9.5 12.0 3.0 11.3 9.5 13.5 8.4 11.3 11.2 8.7 10.4 4.2 5.8 10.0 11.2 10.3 16.1 4.1 3.7 14.3 11.7 14.1 5.1 12.0 4.1 16.5 11.1 14.4 8.9 12.7 29.0 10.7 10.3 13.4 3.0 14.2 9.2 19.7 3.7 20.2 13.8 21.0 17.8 11.9 7.2 6.6 27.8 31.1 23.7 30.7 21.7 18.6 16.2 20.5 21.6 22.8 22.5 21.4 27.9 40.6 28.5 23.5 37.6 19.3 33.4 25.0 31.0 28.4 21.1 32.5 23.0 18.2 24.9 49.1 30.9 19.6 22.7 30.7 33.0 17.6 23.8 27.8 53.0 33.3 22.4 48.0 66.5 34.4 34.4 23.3 21.3 30.6 25.4 42.0 17.4 25.5 25.4 39.6 30.7 44.9 23.4 27.7 15.1 24.7 23.4 35.0 25.0 33.4 32.0 53.0 62.3 64.1 21.3 29.8 30.3 88.8 31.1 53.3 39.5 32.0 58.2 39.0 61.9 45.8 36.9 39.8 41.8 40.0 48.9 55.1 38.0 20.1 92.6 48.4 3.1 5.3 7.8 9.5 4.2 5.8 4.1 3.7 4.1 3.0 3.7 6.6 18.2 19.2 11.0 6.5 29.6 23.6 16.7 10.5 27.3 12.2 15.9 13.7 16.4 17.2 10.7 3.7 4.2 10.3 27.6 9.9 7.9 9.7 12.4 15.6 19.8 13.5 16.8 39.1 13.9 10.8 9.5 12.6 10.7 13.7 13.3 16.6 12.5 11.0 10.7 10.1 13.1 8.0 8.2 23.3 12.4 5.4 9.3 15.1 19.6 15.9 15.0 7.6 25.7 10.1 20.5 10.1 15.0 11.7 17.3 16.2 8.5 11.2 8.9 14.4 19.7 13.2 14.5 27.2 14.3 19.5 19.9 10.3 27.3 9.5 10.0 18.4 CCAR2 "DBC-1, DBC1, KIAA1967, NET35" ENSG00000158941 "Cell cycle and apoptosis regulator 2" Q8N163 8 22604632-22621514 "Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, DNA damage, mRNA processing, mRNA splicing, Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Metalloenzyme inhibitor, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019907, HPA019943, CAB072827, CAB072828" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA 19000 "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nuclear bodies" "CAB072827: , CAB072828: , HPA019907: AB_1852452, HPA019943: AB_1852454" "unprognostic (3.42e-2)" "unprognostic (5.78e-3)" "unprognostic (2.46e-3)" "unprognostic (1.33e-2)" "unprognostic (6.87e-2)" "unprognostic (2.23e-2)" "unprognostic (5.13e-2)" "unprognostic (8.56e-2)" "unprognostic (2.97e-1)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (1.54e-2)" "prognostic favorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (2.46e-1)" "unprognostic (7.54e-2)" "unprognostic (1.77e-1)" 64.1 68.3 39.2 75.4 44.2 145.5 64.4 40.2 52.4 65.6 45.6 68.5 52.1 75.0 33.0 63.4 67.9 59.7 52.0 47.0 33.8 54.8 41.1 61.4 86.7 36.9 42.3 74.6 56.4 59.8 65.1 54.0 38.6 61.1 45.6 59.8 61.5 46.9 101.4 89.0 69.3 44.9 34.7 85.6 60.0 89.4 39.6 96.0 60.6 43.5 74.3 65.4 57.6 47.9 133.7 242.8 230.8 120.8 89.5 74.7 154.0 127.7 124.9 184.3 163.9 219.5 107.4 218.6 156.4 140.5 169.6 163.2 214.5 151.9 132.9 89.2 128.2 259.1 189.5 172.8 82.9 143.6 212.0 77.8 133.1 147.0 90.0 106.4 134.4 194.4 276.2 134.8 138.0 157.5 435.0 150.5 337.6 143.2 88.1 286.7 190.7 116.8 95.2 311.7 115.1 267.6 143.7 163.0 112.6 110.7 148.8 133.2 219.3 135.8 178.4 165.3 171.1 98.5 134.0 261.4 152.7 123.4 215.7 25.9 16.2 23.5 34.8 26.6 29.4 18.7 26.5 26.6 16.6 17.5 25.7 28.4 5.7 19.9 35.6 15.5 32.6 25.8 39.2 44.2 40.2 52.4 47.0 33.8 36.9 42.3 38.6 34.7 39.6 47.9 14.4 16.0 4.2 11.1 14.1 13.9 9.5 12.2 17.6 12.9 13.5 13.1 7.5 15.7 9.4 16.5 16.7 27.3 19.4 24.1 9.8 18.1 4.7 14.1 12.3 13.1 22.2 16.4 12.5 18.0 22.2 12.8 18.8 14.3 8.8 20.2 11.7 12.0 15.7 10.1 11.9 19.6 14.2 11.9 8.5 7.3 14.9 11.0 12.4 10.3 11.2 15.9 20.6 11.1 10.3 23.6 10.4 12.0 14.8 11.7 14.4 9.4 19.5 12.9 19.7 12.4 12.2 30.0 24.1 16.9 15.3 23.7 19.3 23.5 21.7 10.5 CCDC174 "C3orf19, FLJ33839" ENSG00000154781 "Coiled-coil domain containing 174" Q6PII3 3 14651746-14672659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 152.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043468, HPA060129" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA043468: AB_2678493, HPA060129: AB_2684208" "unprognostic (6.10e-2)" "unprognostic (7.96e-2)" "unprognostic (2.92e-1)" "unprognostic (3.26e-2)" "unprognostic (6.58e-3)" "unprognostic (5.06e-2)" "unprognostic (6.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (5.29e-2)" "unprognostic (3.86e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.15e-2)" "unprognostic (2.30e-3)" "unprognostic (2.04e-1)" "unprognostic (2.64e-1)" "prognostic favorable (3.81e-5)" 9.5 7.0 7.7 7.0 8.5 17.2 9.2 8.8 8.5 10.9 6.8 9.8 9.4 10.4 7.5 8.9 9.4 6.8 8.2 7.7 8.0 8.9 8.7 7.1 9.6 8.1 8.4 14.7 10.1 11.9 8.6 8.6 8.1 9.7 7.3 6.7 8.6 8.0 11.1 9.7 9.5 7.9 7.5 10.6 10.3 9.1 8.2 11.6 9.0 10.7 10.2 9.6 9.5 9.6 6.2 6.7 10.0 10.7 13.6 11.1 25.3 8.1 11.6 10.0 7.8 7.5 7.0 12.8 5.8 7.2 6.8 5.3 7.3 6.8 7.8 9.7 8.9 13.0 8.1 8.1 19.7 12.9 14.5 12.9 17.0 13.5 16.5 14.0 8.6 13.4 13.2 11.4 7.6 10.9 13.6 11.3 13.5 10.1 10.9 10.1 9.3 10.6 10.4 10.8 4.8 13.1 9.5 7.4 13.4 11.6 11.2 18.1 8.0 8.0 7.8 7.4 9.5 15.0 14.3 14.7 8.0 9.8 11.1 25.4 10.7 22.2 12.9 11.3 15.2 17.4 16.1 15.1 9.7 16.4 17.4 13.8 20.5 18.8 12.2 10.9 12.5 10.0 7.7 8.5 8.8 8.5 7.7 8.0 8.1 8.4 8.1 7.5 8.2 9.6 29.5 9.6 34.5 11.4 48.0 16.2 31.3 38.0 26.7 32.8 25.0 28.4 37.0 32.9 35.7 12.9 20.9 32.1 42.3 27.3 56.7 34.7 152.5 27.3 35.4 31.0 18.5 43.4 12.8 34.9 25.2 33.7 20.4 34.7 52.0 22.0 38.6 29.3 26.5 15.2 16.6 34.1 32.6 27.2 16.5 59.1 33.5 30.5 14.2 5.6 45.2 22.2 34.0 11.1 15.8 38.2 34.9 40.3 34.9 28.8 36.8 46.4 31.1 24.9 32.9 28.4 37.2 78.7 33.5 19.9 13.5 65.7 41.6 23.5 23.1 31.8 CCDC59 "BR22, HSPC128, TAP26" ENSG00000133773 "Coiled-coil domain containing 59" Q9P031 12 82223681-82358805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038555 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA038555: AB_10669543" "unprognostic (1.61e-1)" "unprognostic (6.28e-3)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "unprognostic (6.73e-2)" "unprognostic (1.42e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-2)" "unprognostic (2.62e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (5.73e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" "unprognostic (1.02e-2)" 12.9 6.3 7.1 5.2 7.4 40.3 10.9 7.8 10.3 9.2 3.7 10.0 4.2 9.2 10.9 10.6 10.0 7.0 9.0 7.1 6.5 6.5 9.7 8.0 8.8 7.4 6.1 11.3 7.8 9.6 6.7 9.6 7.0 7.0 7.5 4.7 6.7 6.7 16.0 8.5 6.0 8.0 6.1 6.3 7.4 12.3 6.9 12.5 8.6 19.3 11.1 11.1 8.7 10.2 27.2 22.9 18.9 16.0 22.5 20.1 33.1 24.0 28.5 43.4 35.3 52.9 16.0 31.0 12.0 26.0 29.9 18.3 95.3 46.7 36.4 35.7 51.3 34.3 15.1 34.6 66.7 40.3 15.7 36.1 39.0 43.5 55.9 34.6 35.9 55.8 62.8 17.1 26.9 50.6 39.6 57.1 30.4 25.6 54.4 28.4 31.9 27.6 23.4 28.4 33.8 16.4 27.4 15.6 34.6 23.1 32.3 55.0 17.6 18.0 16.3 15.1 45.7 22.7 30.2 66.2 15.7 32.8 29.0 25.9 9.2 18.3 10.7 12.6 22.0 16.4 19.0 20.9 9.9 24.1 22.2 18.7 22.3 14.9 19.0 21.4 29.5 5.9 7.1 7.4 7.8 10.3 7.1 6.5 7.4 6.1 7.0 6.1 6.9 10.2 76.6 67.3 56.3 10.1 81.7 85.8 129.9 84.9 65.4 33.7 57.3 80.1 44.3 40.0 66.5 44.1 22.9 80.0 88.2 33.1 129.1 48.7 125.8 63.1 71.5 62.0 35.8 41.2 9.4 57.5 88.3 61.5 29.6 85.0 78.6 45.8 64.2 53.9 56.8 43.7 9.9 62.5 50.8 70.9 53.8 28.4 53.4 62.0 48.0 5.6 66.9 47.2 64.9 12.1 17.2 54.8 44.0 53.8 54.7 88.1 56.1 93.0 51.5 40.6 19.7 118.1 57.8 204.9 135.2 57.6 89.9 146.8 95.6 43.5 56.7 100.6 CCNG2 ENSG00000138764 "Cyclin G2" Q16589 4 77157207-77433388 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.1" HPA034684 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Cytosol" "HPA034684: AB_10669894" "unprognostic (2.58e-1)" "unprognostic (3.00e-1)" "unprognostic (1.46e-2)" "unprognostic (2.29e-1)" "unprognostic (5.73e-2)" "unprognostic (8.15e-2)" "unprognostic (8.40e-3)" "unprognostic (1.72e-2)" "unprognostic (1.20e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.57e-4)" "unprognostic (2.04e-1)" "prognostic favorable (2.47e-5)" "unprognostic (7.98e-2)" "unprognostic (2.20e-1)" "unprognostic (2.28e-1)" "unprognostic (1.05e-3)" 46.4 23.6 15.5 35.6 18.2 88.0 81.5 64.3 20.8 39.6 8.3 33.5 28.0 39.2 26.7 136.0 18.8 32.8 14.9 17.5 11.4 71.0 11.0 26.3 73.5 13.5 14.7 37.4 14.7 46.3 8.8 64.6 13.5 78.1 34.4 81.2 34.3 31.4 12.3 29.2 25.1 33.8 13.1 48.1 25.4 11.2 15.2 67.3 53.2 34.4 73.5 53.5 37.1 19.2 30.9 3.9 66.5 35.5 43.1 54.9 45.0 25.4 72.6 19.4 36.0 4.6 43.8 61.7 40.0 23.7 18.4 21.7 17.6 83.8 37.2 43.2 11.8 5.2 18.1 9.1 22.4 9.3 62.1 46.9 40.8 9.1 19.9 64.6 29.4 35.9 3.0 36.7 36.0 12.0 42.9 19.7 6.8 15.0 4.1 24.3 64.8 4.1 121.9 84.1 17.7 56.1 30.0 46.7 18.0 39.4 34.9 13.8 27.6 26.3 26.0 19.1 4.2 26.9 21.9 43.8 18.4 14.4 13.4 14.8 1.7 21.0 0.9 2.7 2.1 3.2 1.3 1.0 1.9 6.3 1.0 0.6 8.0 2.1 3.1 2.8 6.1 0.8 15.5 18.2 64.3 20.8 17.5 11.4 13.5 14.7 13.5 13.1 15.2 19.2 25.0 12.8 12.3 14.7 55.8 37.1 29.0 27.8 113.8 112.4 101.1 53.6 4.7 8.6 25.4 55.2 22.9 29.7 35.5 57.6 86.1 33.7 0.8 50.4 44.6 35.7 16.7 1.7 13.8 19.6 98.7 61.5 18.3 107.7 39.3 20.3 35.3 3.9 32.3 25.2 26.7 38.0 50.8 45.3 56.7 2.3 27.7 35.8 56.9 10.3 61.8 28.4 17.5 17.1 13.9 49.2 24.6 27.4 20.5 74.3 29.6 70.9 15.3 46.8 65.7 61.3 41.5 9.2 10.1 40.8 26.7 15.7 31.1 17.1 16.1 57.8 CCNJ "bA690P14.1, FLJ10895" ENSG00000107443 "Cyclin J" Q5T5M9 10 96043394-96060870 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 42.1;AN3-CA: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036531, HPA058151" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Golgi apparatus" "HPA036531: AB_10696656, HPA058151: AB_2683623" "unprognostic (1.32e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-2)" "unprognostic (4.37e-2)" "unprognostic (1.14e-1)" "unprognostic (8.61e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (6.65e-2)" "unprognostic (4.88e-2)" "unprognostic (1.77e-3)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (1.83e-1)" "unprognostic (1.08e-2)" 3.6 4.5 1.9 4.2 2.4 11.5 3.9 2.9 2.1 3.3 1.7 3.3 4.4 4.3 3.1 2.7 2.8 3.8 2.2 1.7 2.5 2.6 2.5 3.1 4.9 2.5 2.2 2.8 4.3 5.0 2.1 3.5 2.4 3.3 3.6 4.0 2.7 3.1 3.8 2.9 3.6 3.4 2.1 5.0 2.8 4.2 2.4 4.0 3.2 4.0 3.9 4.4 1.8 2.6 9.0 6.6 42.1 42.2 4.2 3.1 6.1 5.6 5.9 7.7 6.9 17.2 3.7 12.3 6.4 5.4 6.5 5.2 27.4 5.9 10.0 6.1 11.8 12.0 5.2 26.0 9.7 12.0 5.4 5.7 8.2 7.5 17.3 7.6 18.8 11.0 17.6 0.2 4.9 8.6 20.9 14.8 23.6 0.8 6.0 24.3 2.0 0.9 9.4 8.1 6.4 22.2 6.2 1.8 12.6 14.1 10.1 13.7 9.1 4.8 11.1 5.6 13.1 2.5 1.0 11.5 5.8 20.5 3.3 0.1 1.7 0.5 0.9 1.4 1.2 0.7 0.8 0.4 2.9 0.7 1.1 1.1 0.1 0.4 1.3 0.6 0.7 0.9 1.9 2.4 2.9 2.1 1.7 2.5 2.5 2.2 2.4 2.1 2.4 2.6 2.6 6.4 3.1 2.3 3.3 1.9 3.1 1.3 2.8 5.1 3.1 2.0 4.0 1.5 2.4 5.5 14.6 1.5 2.1 3.4 3.9 2.9 3.7 2.6 4.8 4.8 4.2 4.2 4.2 2.7 3.0 3.2 2.0 2.5 0.0 4.6 10.4 1.4 3.6 1.7 5.8 3.5 2.0 6.5 4.6 7.6 1.8 5.0 1.8 1.9 2.8 3.1 1.0 5.5 3.7 4.0 1.5 1.9 1.9 4.0 1.4 2.1 4.3 3.2 0.0 4.1 4.0 10.1 6.9 2.3 1.4 1.1 2.2 3.1 3.2 2.9 CCNK CPR4 ENSG00000090061 "Cyclin K" O75909 14 99481169-99535044 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" Cyclin "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 102.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000645, HPA077073" Supported Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA000645: AB_1078606, HPA077073: AB_2732331" "unprognostic (8.07e-2)" "unprognostic (9.32e-3)" "unprognostic (9.52e-2)" "unprognostic (1.52e-2)" "unprognostic (5.83e-2)" "unprognostic (6.71e-2)" "unprognostic (9.22e-4)" "unprognostic (1.50e-2)" "unprognostic (2.06e-1)" "unprognostic (1.64e-1)" "unprognostic (4.78e-3)" "unprognostic (8.94e-3)" "unprognostic (7.74e-2)" "unprognostic (3.93e-1)" "unprognostic (2.73e-1)" "unprognostic (1.06e-1)" "unprognostic (6.21e-2)" 20.7 18.0 8.8 26.6 10.2 102.1 16.9 11.5 12.8 17.9 10.5 26.3 25.5 18.9 18.8 25.5 22.1 18.5 19.3 9.8 11.8 16.6 17.9 21.7 28.4 11.9 10.8 25.8 16.7 13.5 19.7 19.8 10.9 17.0 28.0 16.3 20.7 16.2 39.2 22.1 27.7 19.8 9.1 24.9 25.0 45.4 10.6 33.3 20.0 22.4 34.1 21.5 19.1 12.9 53.9 59.3 59.7 50.2 47.5 49.4 109.3 69.9 62.2 71.4 82.3 86.3 69.7 84.3 47.7 75.9 53.1 59.9 64.3 89.9 99.5 83.0 33.7 78.1 38.6 75.2 62.4 111.1 85.6 53.7 68.2 71.1 81.4 33.8 54.4 82.9 72.1 72.8 62.7 115.1 85.9 44.6 59.0 66.2 52.1 76.5 80.2 44.7 39.8 101.1 49.1 36.5 62.7 31.9 28.6 57.7 87.4 49.6 66.5 25.6 40.7 226.1 63.3 61.7 86.6 101.5 65.5 50.9 53.4 5.3 5.3 12.6 7.2 5.7 6.3 5.4 5.6 6.4 4.7 4.9 6.5 6.0 12.8 5.1 6.2 5.0 6.3 3.4 8.8 10.2 11.5 12.8 9.8 11.8 11.9 10.8 10.9 9.1 10.6 12.9 29.6 12.8 37.9 13.7 41.8 36.8 48.6 31.3 33.6 16.9 29.5 23.6 11.5 14.3 37.7 22.0 20.9 23.5 52.7 36.0 13.7 20.1 51.5 39.2 39.6 24.1 19.7 39.2 13.7 24.7 29.3 27.6 49.5 56.7 20.3 29.3 25.7 18.7 24.2 18.5 14.0 34.2 30.5 32.7 32.1 22.0 22.4 41.1 17.8 16.9 38.0 13.4 47.4 14.1 18.5 31.8 26.4 18.0 44.9 42.1 26.2 17.2 43.4 28.8 0.0 40.1 23.0 78.9 64.3 35.7 45.3 27.2 46.5 24.9 32.4 70.2 CCNT2 ENSG00000082258 "Cyclin T2" O60583 2 134918235-134959342 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005559 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA005559: AB_1078608" "unprognostic (2.49e-2)" "unprognostic (1.19e-1)" "unprognostic (9.57e-2)" "unprognostic (1.25e-1)" "unprognostic (4.92e-2)" "unprognostic (2.65e-3)" "unprognostic (1.85e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.44e-4)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.33e-1)" "unprognostic (8.51e-2)" "unprognostic (9.94e-2)" "prognostic favorable (3.28e-4)" 13.4 12.1 10.1 12.2 10.2 29.0 15.6 13.7 12.4 16.4 10.6 13.0 13.4 13.5 14.8 12.8 14.0 9.4 11.7 9.9 10.8 10.9 18.3 14.9 15.5 10.4 10.0 17.4 19.8 15.0 15.1 12.0 10.8 13.5 12.1 19.0 13.0 10.7 10.3 15.4 14.4 8.5 11.1 15.6 14.8 12.3 10.5 14.4 14.5 9.7 14.1 15.0 16.3 14.4 9.0 4.4 28.0 10.5 13.6 13.7 21.3 12.2 9.9 11.2 13.9 11.9 10.1 14.6 8.9 10.0 5.4 11.4 17.0 9.1 16.3 7.9 11.5 15.8 11.9 16.9 13.3 14.3 13.4 12.6 17.6 11.1 13.5 14.4 16.8 10.8 13.4 14.6 13.2 6.1 16.0 21.2 22.8 7.4 9.0 15.2 10.0 11.7 17.4 24.4 19.1 15.8 8.9 10.3 14.2 20.3 10.8 17.3 15.3 14.4 15.9 6.2 9.0 10.2 6.7 15.1 9.0 11.2 12.5 3.8 1.6 2.0 1.7 2.0 2.1 1.6 1.9 2.1 2.1 1.2 3.3 2.6 2.1 2.8 1.0 1.9 2.6 1.3 10.1 10.2 13.7 12.4 9.9 10.8 10.4 10.0 10.8 11.1 10.5 14.4 27.1 25.6 26.0 49.6 38.0 15.0 28.8 17.9 26.7 34.7 21.6 15.4 23.5 14.3 21.8 14.7 33.3 11.9 35.3 22.4 7.9 16.2 5.5 20.2 30.2 21.5 18.5 20.0 73.6 14.9 9.6 23.7 46.9 33.1 11.4 31.1 18.9 20.9 10.1 42.1 70.1 16.4 6.1 15.7 22.1 14.6 14.0 25.2 8.8 52.5 23.6 12.9 19.6 76.9 81.8 14.2 19.0 22.2 26.5 35.4 19.1 7.0 12.4 34.5 19.7 17.7 24.2 17.7 23.6 25.3 18.2 13.7 29.0 25.2 17.1 50.5 CD58 LFA3 ENSG00000116815 "CD58 molecule" P19256 1 116514534-116571039 "CD markers, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 144.1;Langerhans cells: 195.9;monocytes: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 135.9" "Low region specificity" "Detected in all" NA NA 6500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (4.48e-3)" "unprognostic (3.20e-1)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "unprognostic (8.45e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.32e-6)" "unprognostic (9.84e-2)" "unprognostic (7.17e-2)" "unprognostic (4.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.68e-2)" "unprognostic (2.17e-2)" "unprognostic (9.66e-2)" 22.7 10.1 7.5 24.8 8.2 57.9 18.0 8.0 10.5 13.6 10.2 22.3 28.8 12.8 16.1 25.4 12.5 21.5 34.3 7.4 8.8 20.0 12.7 29.1 19.0 9.2 8.4 5.4 7.0 11.9 6.7 16.9 9.4 9.3 29.0 2.0 20.7 10.3 8.7 20.0 29.6 16.9 8.6 24.7 19.0 6.8 9.0 9.7 13.2 10.8 20.3 29.7 19.7 10.2 36.4 20.5 14.7 14.2 24.4 40.7 9.3 18.2 31.3 31.0 30.2 9.2 68.4 6.5 33.2 31.8 36.2 45.9 11.0 31.4 32.7 35.8 12.8 32.8 36.9 12.9 15.5 45.8 43.5 11.2 41.4 25.9 23.0 66.4 17.9 8.5 29.4 135.9 19.2 64.7 19.8 34.6 7.3 53.7 22.3 38.4 49.9 8.6 63.0 29.4 4.9 10.3 36.6 26.9 108.3 15.1 14.0 16.8 33.8 22.3 17.1 30.3 47.2 20.6 39.4 4.6 51.3 22.4 113.2 133.7 50.6 89.8 37.3 51.0 26.1 20.7 32.7 31.7 43.9 9.5 4.2 18.2 165.7 18.5 64.4 5.0 64.3 37.4 7.5 8.2 8.0 10.5 7.4 8.8 9.2 8.4 9.4 8.6 9.0 10.2 52.3 9.6 31.5 10.1 23.8 18.2 20.0 144.1 15.4 0.2 9.9 7.1 28.9 30.0 63.2 14.7 0.0 4.4 40.2 48.1 3.9 39.4 3.2 16.0 5.1 38.1 10.8 46.7 3.2 27.6 1.6 31.9 13.3 19.0 53.0 3.4 28.2 7.7 58.7 1.7 1.5 18.7 34.6 33.0 195.9 3.6 10.5 72.2 12.4 45.0 156.1 3.3 34.0 4.5 1.4 46.7 41.7 11.7 24.3 16.9 46.3 26.5 41.3 0.7 32.9 27.9 23.6 11.3 2.4 28.2 27.8 1.9 44.7 9.6 18.6 42.6 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC40 "EHB3, FLJ10564, PRP17, PRPF17" ENSG00000168438 "Cell division cycle 40" O60508 6 110180141-110254275 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046620 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA046620: AB_2679722" "unprognostic (4.19e-3)" "unprognostic (2.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (3.64e-2)" "unprognostic (3.42e-2)" "unprognostic (5.24e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (9.27e-2)" "unprognostic (1.92e-1)" "unprognostic (4.68e-2)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (3.01e-1)" "unprognostic (2.09e-1)" 11.1 14.7 6.9 13.3 10.3 38.2 13.6 6.5 10.9 11.3 7.3 11.1 11.1 11.7 10.4 10.7 11.0 10.4 10.5 10.2 6.1 16.3 16.9 11.0 19.6 4.7 5.0 16.1 12.4 14.0 9.4 9.9 5.0 12.5 12.1 14.8 11.0 9.4 11.6 10.6 11.0 10.1 5.2 16.0 11.4 11.8 5.2 18.6 15.9 11.6 18.6 12.6 8.5 9.2 11.3 10.4 18.2 31.8 18.3 18.8 14.8 21.5 26.4 21.3 26.9 22.8 11.3 37.8 23.7 19.2 22.7 15.8 28.2 17.5 30.1 30.5 21.3 31.0 14.4 12.4 24.2 40.2 39.8 17.1 16.4 22.5 18.1 15.9 21.6 24.3 31.5 22.0 21.3 11.0 29.9 14.9 18.1 15.1 11.2 26.0 21.4 13.1 15.5 23.6 19.4 19.1 15.8 13.8 15.9 16.6 12.8 38.1 24.5 11.5 11.4 27.3 24.1 11.0 15.9 33.8 18.6 33.2 17.4 28.6 18.7 20.4 13.8 20.3 13.7 29.5 13.7 14.3 15.9 28.3 16.2 14.1 20.8 16.5 23.4 24.9 16.8 10.2 6.9 10.3 6.5 10.9 10.2 6.1 4.7 5.0 5.0 5.2 5.2 9.2 38.9 32.1 37.6 18.3 85.7 26.4 26.2 43.1 36.5 94.4 32.2 32.8 21.5 30.0 37.5 27.6 43.8 32.9 79.2 20.9 56.7 35.8 257.8 34.6 48.4 35.5 26.4 44.2 65.4 37.3 30.9 35.8 35.2 30.4 49.4 43.0 38.9 56.6 37.8 94.2 25.6 29.8 22.4 44.9 28.6 84.6 67.4 49.6 10.6 24.4 76.0 46.1 57.7 27.2 43.6 28.5 28.9 45.1 27.8 23.4 29.1 74.0 31.0 84.0 78.9 38.2 39.3 20.9 22.5 37.6 27.1 28.7 59.0 70.6 35.5 22.4 CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22025511-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" 177.4 116.1 91.7 160.2 96.5 402.9 142.7 100.1 113.8 128.6 98.4 198.2 142.3 131.3 99.8 162.3 124.8 131.7 117.0 95.2 108.8 158.8 153.5 154.1 167.9 115.5 103.7 105.9 82.5 128.4 59.6 170.3 108.4 108.3 185.4 95.9 103.8 107.5 119.9 132.0 156.9 175.0 107.4 157.5 159.9 64.2 102.2 157.7 110.6 120.9 216.8 194.8 114.9 127.1 341.9 146.4 272.2 222.0 295.0 306.4 274.2 347.3 318.8 365.5 336.2 178.0 374.5 253.1 272.8 416.7 136.2 210.7 241.1 369.3 431.1 332.4 180.1 438.1 184.5 225.4 259.1 388.5 350.5 285.6 396.6 341.0 195.2 234.7 535.6 157.8 250.8 273.4 430.2 135.6 242.9 307.5 170.2 242.9 179.3 199.6 297.6 243.3 316.2 301.3 183.4 175.8 293.4 228.7 263.4 296.3 242.3 219.1 466.3 265.3 265.2 349.3 207.8 148.6 355.9 305.8 234.5 419.3 277.6 244.3 200.6 255.1 142.4 282.3 144.3 108.0 152.0 146.7 162.3 103.4 109.5 143.5 308.3 145.0 352.2 107.2 157.4 244.8 91.7 96.5 100.1 113.8 95.2 108.8 115.5 103.7 108.4 107.4 102.2 127.1 502.1 60.9 51.8 20.9 301.0 450.6 385.5 266.0 136.1 119.1 281.1 179.6 86.9 231.6 168.0 312.6 18.8 349.6 470.1 434.9 375.6 441.3 38.0 350.5 356.5 307.7 300.4 243.0 58.5 441.9 499.6 225.2 152.4 425.8 163.6 138.2 277.0 230.9 439.2 106.0 71.0 315.4 187.2 585.4 875.2 41.3 157.8 443.4 423.4 53.4 654.9 102.5 286.3 41.7 72.9 570.5 369.7 177.1 192.9 323.1 283.1 578.2 176.2 65.2 236.7 174.2 308.3 155.3 116.2 176.6 556.6 551.6 379.2 178.6 286.7 469.6 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 307.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 9.5 7.6 2.5 14.0 1.9 34.3 9.5 8.0 4.0 11.0 4.1 9.8 9.9 10.8 6.0 10.4 9.2 9.2 6.8 1.6 2.9 8.0 12.3 9.2 15.1 3.0 1.7 11.9 8.7 13.0 6.2 11.5 1.6 9.8 10.4 11.7 9.2 9.3 6.7 10.6 10.4 10.0 0.3 12.9 10.3 17.7 3.4 17.9 12.2 7.8 15.3 13.1 9.1 3.3 31.9 40.0 24.9 22.2 17.2 19.0 21.1 28.9 24.7 39.9 29.0 48.1 19.8 45.4 24.6 31.1 38.7 51.8 49.2 36.6 38.4 29.6 38.7 49.7 26.9 36.3 16.4 66.9 33.4 20.4 25.0 48.2 37.6 16.0 24.4 27.7 85.2 30.7 22.9 14.3 57.9 17.7 23.8 16.0 16.9 36.8 50.3 25.7 14.8 38.8 24.6 15.7 37.0 307.8 25.1 34.8 38.5 29.3 26.4 34.5 27.6 24.5 37.9 23.6 18.4 63.5 24.2 28.2 23.0 11.2 2.0 3.2 2.6 1.5 1.8 1.8 1.5 1.7 1.2 3.1 1.7 1.6 7.0 4.5 1.3 2.7 1.2 0.7 2.5 1.9 8.0 4.0 1.6 2.9 3.0 1.7 1.6 0.3 3.4 3.3 41.4 25.6 29.1 50.9 59.0 64.6 58.5 31.2 50.1 46.6 38.1 26.9 14.5 32.9 40.3 38.6 64.6 33.2 59.0 44.6 13.7 30.2 25.1 49.8 63.4 40.6 31.1 39.3 53.9 27.5 29.9 39.2 45.3 63.1 29.1 43.8 32.2 46.3 27.4 35.3 52.9 39.6 42.7 45.9 49.1 17.3 37.3 41.3 26.6 32.8 41.4 27.8 48.4 47.3 53.1 47.9 33.9 33.8 53.5 81.5 33.3 16.7 38.1 65.4 32.9 48.0 48.5 140.2 104.8 53.0 69.0 58.3 59.0 46.0 39.9 84.8 CDKN2AIP "CARF, FLJ20036" ENSG00000168564 "CDKN2A interacting protein" Q9NXV6 4 183444635-183449064 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 207.0;Glandular and luminal cells: 333.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 161.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041397, HPA062142" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA041397: AB_10794297, HPA062142: AB_2684696" "unprognostic (9.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (7.20e-2)" "unprognostic (1.52e-2)" "unprognostic (7.65e-3)" "unprognostic (6.70e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.93e-2)" "unprognostic (4.69e-2)" "unprognostic (2.25e-3)" "unprognostic (2.23e-2)" 11.7 11.7 10.1 11.9 10.7 38.0 15.5 13.4 13.4 12.8 9.9 14.3 19.0 15.7 12.3 22.2 11.8 12.9 10.3 9.8 10.4 18.3 17.5 11.2 19.8 10.2 10.2 22.6 18.5 15.4 11.4 13.9 10.1 12.8 13.6 13.1 12.8 13.0 9.0 12.0 17.3 9.7 10.9 14.3 17.8 20.1 10.8 24.0 13.5 14.2 18.8 11.8 12.3 12.3 14.4 8.1 23.2 16.8 19.0 14.0 17.7 23.9 19.9 23.9 16.0 11.9 13.5 47.1 4.9 16.1 10.0 11.3 21.0 17.3 25.1 19.4 12.6 49.7 39.4 15.9 14.8 37.3 19.5 16.3 15.6 14.3 18.7 12.6 19.1 18.0 25.1 50.4 16.5 7.8 41.6 30.5 17.0 5.5 16.2 36.1 11.2 19.5 161.1 13.5 23.9 20.7 17.2 72.0 29.9 14.9 10.5 32.0 11.0 8.5 12.3 7.9 19.6 24.4 10.9 25.0 13.3 31.4 13.9 61.0 8.0 18.6 14.4 9.7 14.9 12.2 17.4 15.4 7.7 14.1 22.6 20.8 9.7 15.0 10.3 5.2 19.2 14.6 10.1 10.7 13.4 13.4 9.8 10.4 10.2 10.2 10.1 10.9 10.8 12.3 49.6 16.0 33.1 3.6 58.9 35.9 38.5 9.1 130.3 21.2 35.5 40.1 18.9 17.2 24.2 16.5 10.4 21.8 51.8 36.4 17.6 12.5 150.8 207.0 48.9 33.5 30.4 32.0 5.8 15.5 14.7 38.8 62.2 333.9 62.1 29.7 16.4 13.5 15.7 21.9 5.8 25.5 20.3 12.6 24.2 70.5 21.1 25.7 21.4 7.5 13.2 24.3 22.6 7.5 9.9 17.6 21.1 17.3 47.2 31.5 37.8 13.1 28.8 21.2 13.1 60.8 37.5 36.6 40.3 124.7 39.8 18.7 55.3 22.4 33.3 60.9 CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.9" "Cell type enhanced" "Detected in many" "Astrocytes: 558.0;Excitatory neurons: 1676.4;Inhibitory neurons: 576.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 200.2;HMC-1: 186.2;REH: 86.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Midbody ring" "CAB016395: AB_2086271, HPA035813: AB_2674797" "unprognostic (1.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.55e-2)" "unprognostic (9.00e-2)" "prognostic favorable (7.61e-4)" "unprognostic (1.57e-1)" "unprognostic (3.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.22e-2)" "unprognostic (2.60e-3)" "unprognostic (2.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.45e-1)" 39.6 5.7 33.7 30.7 42.7 78.9 17.7 0.2 42.0 14.2 0.0 16.5 9.2 15.0 5.0 21.4 13.3 17.2 37.5 42.5 7.2 3.0 4.3 28.2 42.4 0.9 13.9 46.8 4.4 3.5 6.5 8.6 0.4 14.1 17.9 35.4 9.6 12.2 17.6 8.6 23.4 23.2 8.6 31.1 10.3 7.6 23.7 60.7 8.5 15.0 29.4 16.2 8.0 21.0 0.1 0.0 47.6 0.0 7.4 2.7 5.3 7.0 0.2 1.1 0.2 0.1 0.0 0.1 5.3 6.1 0.0 0.1 6.8 0.2 0.4 40.4 11.9 200.2 0.7 0.0 1.7 58.0 186.2 3.0 0.3 0.4 0.0 0.7 6.7 70.6 9.3 80.7 59.6 0.0 71.9 42.0 19.3 0.0 0.0 86.7 50.8 18.0 3.4 0.0 7.1 0.5 0.1 0.2 51.1 15.2 0.0 39.0 0.1 8.9 2.5 29.9 0.1 30.7 30.1 9.3 2.9 68.8 21.6 68.0 43.2 90.8 54.8 57.5 69.2 48.1 54.1 60.5 53.4 51.0 56.1 52.7 115.1 73.5 67.8 37.9 60.9 63.5 33.7 42.7 0.2 42.0 42.5 7.2 0.9 13.9 0.4 8.6 23.7 21.0 20.4 160.3 147.3 558.0 165.6 19.9 3.4 5.8 12.5 68.2 18.8 13.7 122.7 5.7 22.4 12.9 102.2 1.1 233.5 11.8 15.6 1.6 135.9 5.3 11.3 34.7 59.3 45.2 1676.4 2.1 0.9 106.0 11.2 17.0 128.5 0.7 13.2 5.1 90.0 134.6 576.9 37.5 24.4 261.4 134.3 110.3 111.6 192.9 115.6 376.6 263.6 90.5 256.4 324.7 21.6 1.5 16.9 89.5 124.3 10.1 2.4 1.0 5.8 99.2 52.6 117.6 33.7 4.1 11.5 5.7 14.5 1.9 232.5 8.5 23.8 2.4 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 21.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Excitatory neurons: 73.4;Inhibitory neurons: 70.5;Microglial cells: 94.6;Oligodendrocytes: 74.5;Suprabasal keratinocytes: 100.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Nucleoli "HPA021787: AB_1846524, HPA058945: AB_2683860" "unprognostic (5.48e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.20e-1)" "unprognostic (2.43e-3)" "unprognostic (2.64e-2)" "prognostic favorable (3.65e-4)" "unprognostic (4.88e-5)" "unprognostic (8.06e-2)" "unprognostic (3.51e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (6.68e-3)" "unprognostic (9.20e-8)" "unprognostic (1.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.04e-1)" 3.4 3.0 1.7 3.5 2.1 12.3 3.0 5.6 2.1 3.8 0.8 2.4 2.8 2.9 0.7 4.4 2.0 2.8 2.8 2.0 1.5 2.0 1.8 1.9 5.6 1.7 1.4 2.2 2.1 2.4 1.8 3.1 2.0 2.3 2.7 2.4 2.2 1.5 9.0 21.4 1.9 3.0 1.0 2.7 1.8 4.5 1.8 7.1 1.4 4.5 6.4 2.3 4.0 1.8 14.2 8.7 12.0 8.8 4.9 5.3 11.7 14.6 8.2 17.9 14.3 4.0 7.9 18.5 6.7 4.7 16.5 16.8 11.6 8.0 16.6 26.3 15.1 18.6 7.2 5.7 2.6 38.2 17.0 5.8 4.5 17.3 11.1 2.5 9.2 17.5 20.8 25.2 13.8 9.0 53.4 11.6 10.1 26.6 17.9 17.9 20.3 20.0 2.7 14.1 27.8 9.6 16.8 10.5 5.4 8.7 5.6 11.4 4.4 17.4 8.7 26.6 21.2 16.7 21.6 23.9 19.5 18.9 16.1 1.8 1.8 2.6 2.6 6.4 4.7 4.6 3.0 2.3 2.3 3.6 2.7 2.7 0.5 3.5 3.3 3.0 3.5 2.0 1.7 2.1 5.6 2.1 2.0 1.5 1.7 1.4 2.0 1.0 1.8 1.8 3.7 0.0 0.5 17.3 4.5 63.3 4.0 4.5 5.2 6.2 4.0 2.7 2.1 2.8 1.3 0.0 8.4 6.2 3.3 1.6 1.9 1.7 17.5 2.4 4.2 4.4 1.2 11.2 73.4 2.3 9.2 5.8 5.6 2.3 0.0 6.4 2.5 0.9 17.1 1.7 70.5 1.5 0.0 2.1 11.7 4.7 4.4 4.0 14.2 94.6 0.5 2.8 1.0 38.2 74.5 1.1 0.4 4.9 11.9 2.8 0.4 1.8 0.3 7.8 6.6 20.8 9.2 30.2 16.2 9.8 100.9 3.8 3.6 4.4 2.6 2.7 CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.6;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 489.7;Late spermatids: 900.3;Spermatocytes: 490.2;Spermatogonia: 215.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "Karpas-707: 157.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" "HPA022048: AB_1853985" "unprognostic (1.47e-1)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.37e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (4.39e-3)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.67e-3)" "unprognostic (3.34e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.11e-9)" "unprognostic (2.19e-2)" "unprognostic (7.40e-3)" "unprognostic (4.46e-2)" "unprognostic (2.74e-1)" 1.5 1.1 0.1 5.4 0.3 62.6 5.7 0.6 0.3 2.4 0.1 7.8 5.1 1.5 0.7 10.5 0.9 1.1 1.5 0.2 0.2 0.7 3.7 1.7 16.2 0.2 0.2 0.6 1.0 1.4 0.2 4.8 0.6 1.3 8.0 1.5 2.7 0.4 0.9 15.3 5.4 2.7 0.2 2.3 3.7 29.5 0.4 12.8 1.3 0.1 13.6 2.1 3.9 0.5 57.8 17.1 67.9 35.8 4.3 6.4 37.6 40.8 19.4 32.2 21.2 24.8 32.1 45.9 3.8 18.7 20.2 23.0 52.4 33.2 30.6 23.4 23.0 50.4 17.5 12.6 0.7 71.1 29.3 2.7 2.1 33.3 8.4 9.4 32.1 53.9 44.1 157.3 51.1 38.2 111.4 53.0 33.8 12.7 21.5 74.5 24.3 15.6 17.1 26.7 52.0 49.0 31.4 39.4 23.9 25.0 44.1 50.2 20.9 23.8 31.3 23.5 39.7 26.5 29.5 37.6 37.2 55.4 94.5 20.7 0.7 14.2 0.5 2.0 0.4 0.9 0.7 0.8 0.4 0.9 0.6 0.8 0.1 3.5 2.8 1.9 2.5 0.6 0.1 0.3 0.6 0.3 0.2 0.2 0.2 0.2 0.6 0.2 0.4 0.5 1.4 9.6 3.2 0.3 6.5 13.9 6.0 11.5 3.4 0.9 11.5 7.9 2.3 4.3 8.7 1.8 0.0 31.5 5.4 8.9 3.9 4.8 489.7 9.5 4.0 3.8 0.0 115.7 0.4 2.5 48.4 7.3 9.2 6.6 8.9 27.1 1.1 0.9 21.6 0.0 0.4 10.0 10.2 5.1 7.3 900.3 9.0 15.3 0.0 1.0 5.3 0.2 4.1 0.5 1.9 3.0 1.0 6.8 28.3 2.6 0.9 0.7 5.6 1.4 19.7 2.0 7.2 490.2 215.1 29.1 21.5 7.5 6.3 4.4 18.1 11.6 CENPW "C6orf173, CUG2" ENSG00000203760 "Centromere protein W" Q5EE01 6 126340115-126348875 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.6;testis: 39.5" "Cell type enhanced" "Detected in many" "Early spermatids: 329.7;Extravillous trophoblasts: 155.9;Spermatocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA067285 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067285: AB_2685818" "unprognostic (3.51e-3)" "unprognostic (2.35e-1)" "unprognostic (3.26e-3)" "unprognostic (9.61e-3)" "unprognostic (3.78e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.21e-5)" "unprognostic (1.11e-2)" "unprognostic (2.82e-2)" "unprognostic (9.07e-2)" "unprognostic (5.86e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.22e-1)" 8.2 4.3 2.5 12.8 2.3 50.6 6.6 2.0 3.5 14.4 1.4 15.0 8.3 21.6 7.0 23.1 9.2 5.4 1.7 4.2 2.0 3.4 3.6 4.9 15.5 1.9 2.0 4.1 2.1 2.8 2.5 7.8 1.7 6.3 17.5 1.6 8.5 4.4 3.0 8.3 10.8 16.1 1.9 6.8 6.3 39.5 2.0 27.4 2.5 1.9 20.5 6.6 10.9 2.4 73.4 49.0 94.7 82.9 10.3 10.4 81.2 60.0 43.6 81.3 98.3 148.0 50.1 86.8 48.8 38.3 128.7 88.0 78.0 94.3 114.6 94.0 140.2 84.7 141.4 166.3 3.4 123.8 59.1 6.4 10.0 69.1 51.2 23.1 88.3 116.8 144.1 56.5 69.6 119.3 103.1 204.4 60.5 64.0 74.3 107.7 63.2 62.6 38.0 33.0 99.1 44.0 50.8 46.5 67.4 76.9 43.7 119.5 48.0 76.6 78.3 104.6 163.7 36.9 72.7 156.8 45.9 147.0 92.8 3.2 16.9 2.3 2.0 20.3 0.6 6.0 4.4 4.3 15.9 3.5 3.4 2.7 2.9 6.9 14.1 18.9 12.0 5.9 2.5 2.3 2.0 3.5 4.2 2.0 1.9 2.0 1.7 1.9 2.0 2.4 2.5 0.0 2.6 1.0 18.6 38.0 13.4 54.3 6.2 1.3 10.3 18.7 0.3 11.5 29.4 1.8 2.1 52.2 6.1 23.5 5.9 16.6 329.7 18.0 26.5 11.0 7.8 75.1 23.7 17.9 155.9 25.1 17.3 12.7 13.4 31.4 10.8 6.0 63.6 3.3 22.0 27.1 42.7 15.6 40.1 39.3 19.3 19.3 8.8 1.0 12.6 3.1 3.1 1.0 2.4 17.2 10.6 9.1 38.6 24.7 18.1 1.6 7.0 1.4 0.0 6.4 18.1 148.3 83.8 60.9 29.0 21.2 8.6 11.4 51.7 35.8 CEP152 "KIAA0912, MCPH9, SCKL5" ENSG00000103995 "Centrosomal protein 152" O94986 15 48712928-48811146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Dwarfism, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3" "Cell type enhanced" "Detected in many" "Early spermatids: 192.5;Late spermatids: 49.5;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039408 Approved Supported Nucleoplasm,Centrosome NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Centrosome Nucleoplasm "HPA039408: AB_10795288" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.61e-1)" "unprognostic (4.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.87e-4)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" "unprognostic (1.04e-2)" "unprognostic (5.82e-2)" "unprognostic (4.70e-3)" "unprognostic (3.47e-2)" "unprognostic (6.24e-3)" "unprognostic (5.29e-2)" "unprognostic (3.55e-1)" "unprognostic (4.60e-2)" "unprognostic (1.25e-1)" 2.2 1.3 1.2 3.5 1.4 16.3 1.9 2.0 1.9 1.9 2.6 2.3 2.9 1.4 0.9 2.6 1.9 1.8 2.1 1.0 0.9 2.2 1.0 2.2 4.3 1.2 1.2 2.5 2.9 1.3 0.9 4.7 1.4 1.7 3.1 1.9 2.4 0.9 1.0 3.0 2.9 1.9 0.7 2.4 2.3 9.8 1.8 5.6 2.9 0.6 3.7 1.4 2.3 1.8 8.0 6.1 12.2 15.0 2.1 3.9 7.9 13.9 5.6 10.0 12.3 13.2 6.8 18.6 5.9 4.0 14.1 18.6 13.6 5.0 14.5 16.5 8.3 30.1 34.6 7.2 1.4 25.6 13.4 1.4 3.9 11.1 6.6 3.9 7.5 19.2 18.4 21.6 8.6 4.5 18.6 23.8 7.7 9.5 6.1 22.7 16.4 22.9 3.6 7.5 14.6 9.8 10.7 8.9 4.2 13.3 6.7 12.3 6.2 24.4 12.9 18.9 15.6 9.2 10.8 21.4 7.8 36.2 17.6 2.1 1.0 1.9 0.8 1.4 0.7 0.9 0.9 0.9 0.8 1.7 1.0 1.0 1.8 1.2 1.5 1.5 1.0 0.5 1.2 1.4 2.0 1.9 1.0 0.9 1.2 1.2 1.4 0.7 1.8 1.8 3.9 6.4 2.8 22.2 9.3 3.8 4.1 2.8 4.0 1.5 2.9 3.6 3.9 4.3 1.8 3.7 2.1 31.5 6.8 7.8 0.0 4.7 192.5 6.4 5.3 6.7 3.6 29.9 14.7 6.7 8.5 9.0 7.1 5.0 8.2 20.9 6.1 3.3 7.6 0.0 8.4 8.2 4.1 7.2 6.4 49.5 23.9 8.6 1.8 16.9 6.9 2.9 10.3 6.0 7.0 7.9 3.5 27.1 15.9 3.2 9.1 1.7 8.4 3.6 6.6 6.5 5.4 24.4 10.3 7.0 3.4 46.9 9.9 3.4 10.1 4.1 CEP250 "C-NAP1, CEP2" ENSG00000126001 "Centrosomal protein 250" Q9BV73 20 35455164-35519280 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064875 Supported Centrosome NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA064875: AB_2685379" "unprognostic (6.35e-2)" "unprognostic (2.94e-1)" "unprognostic (2.31e-1)" "unprognostic (1.21e-3)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.60e-1)" "unprognostic (7.81e-2)" "unprognostic (3.47e-2)" "prognostic favorable (9.27e-6)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.97e-6)" "unprognostic (1.30e-1)" "unprognostic (6.40e-2)" "unprognostic (2.90e-3)" "unprognostic (4.57e-2)" 7.2 8.4 12.8 13.5 12.8 22.6 6.4 12.7 11.9 11.3 11.3 10.6 6.9 10.5 8.9 10.4 11.8 7.5 6.8 11.6 13.4 6.2 6.7 7.1 23.3 11.6 12.5 14.2 7.3 12.7 12.2 6.5 11.1 12.2 8.3 15.7 10.1 8.7 9.4 13.3 11.2 9.7 9.8 20.2 8.3 18.8 14.9 16.3 8.7 6.9 14.3 9.8 10.4 11.6 33.9 38.2 18.5 34.6 27.6 24.8 27.4 16.5 18.4 25.8 20.3 51.2 27.0 36.4 21.5 23.7 80.4 36.6 20.0 50.7 28.7 6.9 8.2 68.1 31.0 49.0 16.7 33.7 36.6 17.7 30.0 43.7 61.9 29.3 27.0 38.3 23.7 33.8 44.2 17.4 41.5 34.0 12.4 18.0 43.1 23.6 53.6 10.1 24.7 38.4 24.9 27.7 45.6 30.3 21.5 14.9 21.3 29.3 43.7 113.5 29.3 42.4 23.8 11.7 13.6 33.9 63.1 22.4 19.9 20.2 2.0 5.2 10.5 2.5 6.5 5.7 4.4 8.5 4.1 6.7 5.3 6.0 0.8 7.4 1.7 14.1 5.1 4.6 12.8 12.8 12.7 11.9 11.6 13.4 11.6 12.5 11.1 9.8 14.9 11.6 3.4 6.4 7.2 7.5 14.6 1.7 6.2 3.6 8.6 21.7 4.5 5.3 13.0 5.7 12.7 9.2 12.5 11.6 15.7 7.0 5.9 5.5 11.7 16.2 8.0 4.8 3.0 19.5 13.6 2.0 6.4 7.6 11.7 9.7 5.1 11.8 7.1 3.8 9.1 16.8 17.6 5.4 2.0 9.0 2.7 20.0 4.4 7.7 1.8 5.6 4.2 8.3 20.6 5.0 5.1 5.1 3.6 3.8 18.7 5.2 5.1 2.2 19.5 28.7 0.0 9.9 6.7 24.1 14.8 10.6 2.7 3.0 15.9 5.5 6.6 3.8 CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 44.0;Plasma cells: 27.0;Spermatocytes: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 5.0 4.4 1.6 4.8 1.7 6.9 2.1 2.4 2.4 1.2 0.9 4.4 7.3 1.1 2.6 4.5 0.7 1.3 2.5 1.6 2.0 2.9 4.4 1.4 6.6 1.6 1.6 0.6 1.9 1.3 1.6 1.1 1.5 1.7 3.7 3.7 1.7 1.5 4.9 1.2 4.5 2.2 1.3 4.2 4.5 5.4 1.8 4.9 1.0 4.7 6.5 3.2 2.2 1.4 39.9 13.0 13.5 12.1 6.7 3.3 2.9 17.9 3.6 12.5 14.8 9.1 10.0 33.5 25.3 7.8 18.8 14.0 31.1 21.3 21.7 71.3 27.1 26.6 16.3 15.0 10.2 31.8 11.6 4.2 6.2 23.2 17.5 3.3 24.8 23.0 27.8 19.2 16.6 13.0 38.0 26.5 17.5 17.1 23.1 28.6 28.9 34.2 17.3 10.6 16.8 4.7 20.7 15.3 8.7 8.1 9.3 12.5 11.0 7.3 26.1 28.2 29.3 18.9 26.1 28.8 9.9 39.5 10.2 1.3 0.3 0.8 3.5 0.7 3.7 4.3 3.8 3.9 0.8 4.4 4.3 4.1 1.0 1.1 0.5 1.8 3.9 1.9 1.6 1.7 2.4 2.4 1.6 2.0 1.6 1.6 1.5 1.3 1.8 1.4 2.3 0.0 1.1 2.0 11.7 3.4 3.7 7.4 0.6 1.6 2.2 2.0 3.0 7.2 4.1 1.8 0.0 1.9 5.1 3.4 11.7 5.4 13.1 2.2 1.0 3.0 0.0 44.0 4.8 8.0 0.9 1.6 10.2 2.2 1.3 1.5 3.3 7.6 7.8 1.7 4.3 4.6 2.0 1.9 3.0 3.5 2.8 1.7 3.6 1.0 5.8 5.7 8.2 5.0 2.1 7.9 1.4 4.1 27.0 4.1 3.7 9.8 1.9 6.8 0.0 2.4 3.1 47.0 6.6 5.5 3.4 0.4 5.3 5.1 10.6 4.0 CHAF1A "CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150" ENSG00000167670 "Chromatin assembly factor 1 subunit A" Q13111 19 4402640-4445018 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.3;Spermatocytes: 94.3;Spermatogonia: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 15.7;granulocytes: 4.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB015186 Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015186: AB_628065" "unprognostic (1.91e-1)" "prognostic favorable (8.22e-5)" "unprognostic (2.49e-1)" "unprognostic (4.71e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (5.30e-3)" "unprognostic (8.78e-2)" "unprognostic (2.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "prognostic favorable (4.15e-6)" "unprognostic (1.71e-1)" "unprognostic (2.11e-3)" "unprognostic (4.03e-2)" 4.9 4.4 3.5 9.7 3.0 31.4 4.8 5.6 6.6 4.7 1.3 6.9 6.5 3.9 2.0 10.2 4.0 2.7 3.9 3.7 3.0 2.4 4.1 4.0 13.4 3.4 3.1 3.7 3.9 3.3 3.7 6.2 3.0 5.8 6.6 3.4 5.5 3.0 12.2 10.8 6.7 4.1 2.4 6.9 5.1 14.5 3.1 16.3 2.9 4.1 10.5 4.7 5.6 4.1 65.8 44.0 71.8 45.3 7.0 8.5 36.7 61.2 24.8 50.5 56.7 53.5 22.8 100.4 24.7 19.6 28.6 50.3 61.6 41.5 59.8 58.1 67.2 62.9 69.4 42.7 3.5 73.7 48.8 4.8 8.6 41.5 17.7 9.4 24.0 54.9 76.8 88.0 31.3 37.8 119.2 40.7 80.1 33.5 35.6 87.2 56.8 57.2 13.1 76.7 50.6 39.2 41.6 29.1 24.5 45.2 25.7 53.9 17.5 41.3 35.9 71.1 74.9 43.7 71.0 96.3 34.7 92.8 49.9 3.8 2.3 4.7 0.5 2.3 0.4 1.6 0.6 0.1 2.1 1.0 0.5 0.4 1.2 1.2 0.4 15.7 0.9 0.9 3.5 3.0 5.6 6.6 3.7 3.0 3.4 3.1 3.0 2.4 3.1 4.1 2.3 0.0 3.9 2.0 12.5 9.7 4.6 3.5 6.2 12.1 5.1 3.6 5.7 1.5 2.6 5.5 2.1 25.3 17.3 13.9 1.9 8.5 6.7 5.3 4.2 4.6 1.8 50.3 4.1 6.7 37.9 6.1 10.7 6.5 2.5 19.3 3.3 4.8 12.1 1.7 3.6 10.7 0.0 4.8 21.4 6.7 3.1 11.8 1.8 1.9 11.5 5.2 5.2 2.5 2.9 6.8 1.7 3.8 32.5 4.1 4.6 1.8 5.0 8.4 32.9 5.7 5.5 94.3 103.8 18.7 14.9 14.6 7.7 9.4 14.6 5.9 CHD1 ENSG00000153922 "Chromodomain helicase DNA binding protein 1" O14646 5 98853985-98929007 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022236 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli fibrillar center" "HPA022236: AB_2670915" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (1.09e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (7.15e-2)" "unprognostic (6.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-1)" "unprognostic (4.94e-2)" "unprognostic (3.15e-1)" "prognostic unfavorable (7.25e-6)" "unprognostic (2.69e-1)" "unprognostic (3.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.17e-1)" 14.7 10.3 6.9 17.8 7.3 69.6 9.2 17.9 14.1 8.0 8.8 10.5 9.8 12.7 7.0 7.9 8.1 15.0 5.4 6.1 8.3 8.3 13.2 9.4 13.7 9.7 7.7 14.1 10.0 9.4 4.8 14.2 8.8 8.2 10.3 14.9 5.4 7.1 9.7 6.2 9.5 9.0 7.4 15.7 8.2 18.1 7.3 49.6 8.8 9.0 13.8 12.4 5.9 9.3 23.0 20.7 47.5 32.3 15.7 16.1 41.3 23.2 15.1 18.4 23.8 25.9 17.3 19.3 22.0 13.5 29.8 18.6 37.6 25.6 38.2 30.5 28.2 34.2 25.8 19.8 17.3 33.3 25.5 14.0 10.2 32.0 32.2 12.5 22.6 62.0 42.0 28.9 18.7 18.5 66.4 14.4 32.0 7.2 24.8 55.7 33.2 29.2 16.0 21.6 22.1 18.9 29.8 15.4 37.9 24.6 15.0 22.6 25.7 39.3 21.2 24.9 41.6 20.0 22.6 40.0 21.5 32.6 24.2 13.1 7.1 10.1 5.4 6.6 6.9 9.4 5.1 5.3 6.5 8.3 7.0 5.6 14.4 7.4 6.8 4.7 5.9 2.0 6.9 7.3 17.9 14.1 6.1 8.3 9.7 7.7 8.8 7.4 7.3 9.3 87.2 48.1 72.2 35.3 145.3 155.5 99.0 26.6 115.5 39.3 85.9 56.1 29.9 22.8 57.4 36.8 43.8 53.9 203.6 64.0 7.9 36.5 101.0 84.3 114.3 79.5 31.8 40.8 50.9 32.0 38.4 104.6 50.0 107.3 89.2 45.2 40.0 30.6 35.6 33.7 59.8 31.2 16.2 65.8 145.9 19.8 32.3 169.7 67.6 90.9 89.1 20.5 59.8 66.4 72.1 35.3 51.4 19.2 121.0 82.6 28.1 15.5 45.3 49.5 46.0 173.8 113.5 67.1 54.6 74.1 188.5 90.3 148.2 49.9 39.4 75.4 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 12.5 11.9 11.2 13.5 12.5 35.3 14.8 16.3 13.2 12.4 10.5 14.0 9.4 14.8 11.1 14.9 12.9 10.1 12.0 11.1 12.2 11.7 9.6 13.7 18.0 11.4 11.6 17.1 13.6 22.3 13.1 11.7 11.1 13.2 12.3 14.8 13.6 12.1 15.7 22.3 14.7 14.8 11.5 15.8 14.2 12.9 12.5 25.4 14.8 12.7 17.5 12.8 12.9 13.6 31.2 39.6 43.6 20.7 27.7 23.6 24.9 24.4 28.4 36.5 35.4 35.0 26.3 51.4 14.8 33.1 28.4 37.2 54.9 35.1 46.0 39.3 24.2 46.3 27.6 43.5 25.7 64.6 40.4 32.8 27.2 40.9 29.7 28.6 33.4 40.2 32.4 26.7 28.0 33.9 46.1 26.0 33.4 30.9 34.3 42.0 32.9 17.4 27.3 57.9 30.9 30.7 37.5 29.8 21.8 39.7 20.7 30.5 36.4 29.2 23.0 17.8 29.1 30.3 38.4 50.3 12.1 23.2 29.6 9.1 3.8 9.8 5.5 3.8 6.4 4.2 4.9 5.6 2.7 11.2 5.0 4.4 7.9 7.8 6.7 6.1 4.7 2.7 11.2 12.5 16.3 13.2 11.1 12.2 11.4 11.6 11.1 11.5 12.5 13.6 27.6 38.5 56.3 27.4 32.2 12.6 11.3 15.9 23.3 33.3 21.9 22.6 19.6 24.3 32.6 33.1 27.1 14.7 40.0 16.8 1.9 21.8 3.4 32.5 37.9 25.5 27.1 27.8 41.0 23.6 12.3 24.0 27.5 39.5 28.4 41.7 13.9 14.9 17.5 23.5 40.2 16.0 8.2 20.1 9.3 4.1 16.1 25.3 10.6 20.6 27.1 18.9 32.0 29.7 33.1 26.5 13.9 17.7 32.4 16.1 12.0 7.4 28.8 24.3 0.0 32.1 26.2 29.2 25.1 24.6 16.6 12.3 31.4 34.1 16.8 12.7 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP4 "CLIMP-63, ERGIC-63, P63" ENSG00000136026 "Cytoskeleton associated protein 4" Q07065 12 106237881-106304279 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 198.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 106.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 106.8" "Cell line enhanced" "Detected in many" "BJ: 549.7;BJ hTERT+: 687.6;fHDF/TERT166: 834.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000278, HPA000792" Enhanced NA NA 560000 "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA000278: AB_1078527, HPA000792: AB_1078526" "unprognostic (5.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (7.13e-2)" "unprognostic (2.44e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (6.61e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (5.02e-2)" "unprognostic (9.66e-3)" "unprognostic (1.95e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.20e-3)" "unprognostic (6.97e-2)" "unprognostic (1.29e-2)" "unprognostic (3.66e-2)" 26.6 40.0 14.7 34.7 16.1 100.5 21.8 14.2 15.4 49.5 27.9 42.9 19.3 40.6 59.2 71.3 31.2 26.3 40.0 14.2 17.4 21.3 30.4 33.5 10.5 18.1 16.1 30.6 41.1 26.1 20.2 51.8 17.2 37.6 45.8 18.8 57.5 36.9 14.5 39.4 19.0 46.7 15.6 25.1 52.3 9.9 19.6 7.8 19.8 13.5 22.8 51.4 40.5 18.4 86.8 106.7 126.5 138.3 240.6 212.5 73.2 549.7 687.6 262.7 300.1 45.6 19.4 5.6 98.0 834.0 89.3 153.1 93.5 83.5 187.5 3.0 54.1 0.1 56.5 89.9 179.2 0.4 1.7 205.5 111.9 223.5 159.9 331.9 311.7 6.5 0.6 11.0 253.0 29.1 4.4 3.1 73.8 45.6 127.9 40.1 91.0 7.5 80.5 76.9 41.5 46.0 98.0 65.9 54.4 112.9 73.9 39.3 268.9 205.8 112.2 86.3 157.9 29.0 0.3 60.2 148.5 10.9 184.5 106.8 18.8 22.5 1.1 6.8 1.6 9.5 1.7 1.0 5.8 4.1 2.2 2.0 30.1 0.2 11.3 0.2 0.5 7.1 14.7 16.1 14.2 15.4 14.2 17.4 18.1 16.1 17.2 15.6 19.6 18.4 17.7 22.4 26.5 9.1 26.3 54.8 37.9 63.2 56.3 11.8 37.6 34.4 43.2 35.8 33.4 23.9 10.4 26.9 2.8 43.0 5.9 37.8 1.1 38.6 103.1 33.8 41.4 1.3 5.8 87.7 107.0 92.9 51.5 139.9 19.1 62.8 43.2 52.3 20.1 47.1 11.2 198.7 16.2 31.8 16.8 2.7 68.3 33.1 33.8 8.4 59.9 23.4 2.1 7.5 1.6 52.4 22.9 61.3 144.5 92.0 3.9 9.2 13.3 23.3 13.1 45.1 52.3 4.9 12.6 122.3 71.9 26.4 6.7 73.3 69.0 46.7 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC2B "AICL, CLECSF2, HP10085" ENSG00000110852 "C-type lectin domain family 2 member B" Q92478 12 9852369-9869386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;dendritic cells: 255.7;NK-cells: 265.7;Suprabasal keratinocytes: 240.8;T-cells: 276.6" "Cancer enhanced" "Detected in all" "cervical cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 221.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 56.7;ASC TERT1: 87.7;fHDF/TERT166: 49.5;HSkMC: 50.3;U-937: 229.5" "Low region specificity" "Detected in all" HPA008194 Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA008194: AB_1078533" "unprognostic (3.14e-2)" "unprognostic (4.27e-2)" "unprognostic (2.14e-2)" "unprognostic (9.69e-3)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" "unprognostic (5.99e-2)" "unprognostic (4.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.50e-1)" "prognostic unfavorable (5.64e-13)" "unprognostic (8.09e-2)" "unprognostic (7.12e-3)" "unprognostic (5.70e-2)" "unprognostic (2.79e-1)" 32.4 7.4 10.7 21.9 10.8 113.0 23.5 13.1 20.0 23.1 12.5 9.4 7.2 19.9 6.5 17.4 15.5 20.5 14.6 10.7 10.4 8.2 16.3 39.3 32.2 12.2 11.2 33.1 2.5 2.9 4.2 17.6 12.3 9.8 13.5 2.4 12.7 6.0 17.2 80.0 14.0 14.5 11.2 44.7 9.1 3.0 12.8 16.3 10.4 20.6 16.0 19.8 23.9 11.8 0.3 2.6 0.0 0.2 56.7 87.7 0.4 1.6 11.0 0.8 2.9 0.1 1.8 1.2 0.9 49.5 32.8 17.4 8.0 0.1 0.2 1.8 0.1 2.3 0.1 0.1 19.9 2.0 0.4 50.3 18.1 2.2 0.4 2.9 29.1 9.0 0.1 7.4 13.0 0.1 15.2 4.1 0.3 0.0 2.0 20.9 0.4 0.1 0.1 18.3 0.1 0.0 0.8 0.2 13.9 0.2 3.6 0.6 41.8 0.4 9.2 1.6 5.3 13.2 1.2 1.7 13.5 229.5 16.8 54.8 37.8 14.6 68.2 58.1 55.4 12.6 42.3 69.7 34.5 20.0 40.2 62.2 221.4 67.2 75.6 12.6 36.0 84.4 10.7 10.8 13.1 20.0 10.7 10.4 12.2 11.2 12.3 11.2 12.8 11.8 216.3 3.2 23.1 0.0 102.0 201.6 76.4 393.1 106.4 0.1 4.4 7.7 3.6 7.2 122.3 0.0 0.0 0.9 255.7 0.5 0.0 5.1 0.3 5.8 84.2 179.5 1.8 32.8 0.0 0.8 2.0 97.1 3.6 5.5 54.4 1.3 142.8 3.6 74.4 0.0 0.0 1.0 61.1 141.5 208.2 2.4 49.7 183.2 80.0 15.0 59.2 1.1 265.7 0.0 0.2 1.9 0.0 17.7 102.8 23.9 0.3 1.1 17.4 0.7 6.6 45.8 26.4 0.3 0.5 99.9 240.8 1.9 276.6 16.7 1.1 140.9 CLK3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 35.9 28.7 30.3 26.5 31.8 112.4 34.6 36.4 35.9 36.7 32.8 36.6 28.9 32.3 25.9 38.6 31.3 32.7 28.3 30.2 31.2 30.0 29.4 34.0 37.7 32.8 31.6 38.4 33.9 35.3 32.3 31.6 32.5 31.9 21.8 33.1 36.1 29.7 50.7 41.7 33.7 26.2 29.5 41.7 35.1 44.4 32.2 55.8 32.3 52.1 30.3 37.8 33.8 35.4 56.7 35.1 45.5 25.6 57.2 43.4 35.8 37.7 59.2 52.7 64.3 47.9 36.4 51.2 27.2 33.9 73.5 39.0 85.4 36.3 34.3 73.2 46.9 63.0 52.0 33.6 90.7 17.2 46.6 54.8 71.0 69.4 57.4 64.0 58.6 51.0 31.3 36.2 31.1 39.9 50.9 57.3 29.1 55.7 24.6 40.7 21.8 33.7 41.1 40.3 25.5 29.9 30.2 33.0 34.3 34.7 31.4 33.8 27.3 31.0 23.7 19.7 50.2 59.0 51.8 42.2 27.2 82.4 40.1 74.2 65.5 90.0 68.9 74.1 68.2 71.0 73.6 71.9 61.3 78.8 74.4 70.9 115.9 90.7 97.7 69.5 87.7 85.9 30.3 31.8 36.4 35.9 30.2 31.2 32.8 31.6 32.5 29.5 32.2 35.4 29.8 6.4 38.4 14.0 34.1 44.9 44.9 41.6 26.2 35.5 22.8 15.9 18.6 28.6 35.1 12.9 56.3 27.7 41.8 46.7 31.3 34.2 83.6 25.8 19.9 28.6 29.3 31.5 6.6 24.2 46.2 24.5 37.8 41.5 21.5 27.4 21.4 13.4 27.5 28.6 7.9 34.7 42.7 23.3 34.4 19.8 27.7 28.4 28.4 6.5 29.5 18.0 29.9 7.1 9.6 30.8 52.0 20.3 26.6 38.9 35.5 18.6 23.4 42.6 13.1 20.4 35.8 45.4 21.4 21.0 41.9 58.6 40.1 20.4 28.1 63.5 CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage factor polyribonucleotide kinase subunit 1" Q92989 11 57648188-57661865 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057770 Supported Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA057770: AB_2683523" "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-3)" "unprognostic (2.13e-2)" "unprognostic (4.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.82e-2)" "unprognostic (7.58e-2)" "unprognostic (8.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.75e-1)" "unprognostic (8.78e-2)" "unprognostic (3.07e-1)" 8.9 7.4 3.1 10.1 3.6 26.1 9.2 3.9 4.4 7.1 4.4 9.0 8.7 7.7 7.6 9.2 7.3 5.9 6.5 3.3 3.3 8.0 10.1 7.3 10.8 3.3 3.1 6.8 7.4 6.8 4.4 9.2 3.7 5.6 8.6 3.2 6.7 7.1 8.2 9.0 8.4 8.9 3.4 10.0 8.1 8.4 3.3 11.2 7.2 9.3 13.1 8.6 5.0 3.7 21.2 22.2 21.0 21.6 22.3 14.4 19.7 21.4 23.2 30.1 25.8 21.4 18.4 35.1 24.3 18.9 24.2 25.9 29.2 34.5 34.2 24.3 18.0 19.4 13.5 21.7 17.7 28.5 22.2 17.4 24.0 26.9 18.6 11.9 27.7 17.4 30.4 11.9 24.9 14.8 21.8 32.9 31.8 24.3 22.2 21.7 32.1 37.5 16.5 15.0 11.1 22.3 19.1 17.2 28.7 21.7 32.7 23.2 20.0 16.0 21.7 27.7 15.9 18.6 26.4 39.3 17.3 16.3 17.3 31.2 19.0 20.0 15.9 16.4 18.9 15.6 14.1 16.4 19.0 14.3 16.4 14.9 21.7 13.6 15.9 10.8 16.2 12.3 3.1 3.6 3.9 4.4 3.3 3.3 3.3 3.1 3.7 3.4 3.3 3.7 6.1 9.6 5.1 1.0 8.5 19.4 10.7 13.4 16.5 4.3 6.0 6.2 2.4 7.2 10.5 0.0 6.2 16.5 12.7 4.8 9.8 12.9 32.5 6.7 5.7 7.3 2.4 12.2 1.9 11.7 13.9 7.4 3.1 7.1 8.2 4.9 4.2 3.5 11.0 5.0 1.8 3.2 8.2 6.0 6.9 4.1 5.6 5.8 8.8 1.0 15.0 3.3 7.2 2.5 1.4 9.8 4.7 8.6 5.9 4.7 6.2 10.1 6.4 3.1 6.6 10.4 6.9 9.4 12.0 9.3 14.5 13.5 9.7 6.5 4.6 7.8 CNEP1R1 "C16orf69, FLJ38101, NEP1-R1, TMEM188" ENSG00000205423 "CTD nuclear envelope phosphatase 1 regulatory subunit 1" Q8N9A8 16 50024410-50037088 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042815, HPA077906" Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA042815: AB_10794765, HPA077906: AB_2686868" "unprognostic (4.11e-2)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.43e-3)" "unprognostic (1.80e-1)" "unprognostic (3.42e-2)" "unprognostic (8.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (3.37e-3)" "unprognostic (5.09e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" 9.6 8.4 6.4 14.4 7.3 23.8 7.9 8.0 7.1 8.4 5.9 9.4 8.9 9.2 12.9 12.0 7.6 10.7 9.0 6.7 6.6 7.1 10.6 9.5 14.3 6.6 5.9 9.8 7.1 8.6 8.4 15.6 6.6 8.3 13.4 9.6 8.3 8.2 10.1 11.6 9.2 11.0 6.7 13.4 9.8 18.0 6.7 9.5 5.4 7.3 15.3 10.0 9.0 7.9 11.2 10.2 12.4 13.9 23.5 23.1 17.4 22.5 17.1 21.4 12.5 11.0 15.3 12.4 16.3 18.7 14.6 17.0 10.0 10.9 27.1 9.1 11.7 6.1 6.7 17.8 16.7 8.1 18.1 17.0 18.2 13.9 10.8 16.6 14.8 15.5 7.6 6.9 27.4 3.4 16.0 21.0 9.0 4.9 13.8 19.3 16.4 12.8 15.9 7.4 9.3 11.1 21.3 8.5 9.0 10.7 7.4 10.0 19.3 20.7 15.9 19.7 8.0 11.4 11.3 14.5 12.0 8.1 17.4 16.6 21.0 16.3 16.0 29.2 15.1 9.4 12.4 11.9 17.5 8.7 12.4 14.5 51.0 12.7 36.4 6.9 13.4 14.5 6.4 7.3 8.0 7.1 6.7 6.6 6.6 5.9 6.6 6.7 6.7 7.9 8.2 3.2 7.8 8.8 10.1 10.6 3.4 6.5 5.7 5.8 5.9 3.9 11.4 8.6 6.9 7.3 4.2 17.7 10.6 7.7 3.9 5.2 4.6 5.9 8.6 8.6 4.8 7.8 13.7 5.4 25.1 9.7 8.6 6.8 12.7 5.6 10.0 6.9 14.8 6.7 13.2 3.7 2.0 20.0 20.8 3.9 5.9 18.2 16.0 6.5 15.4 12.2 12.3 8.5 12.5 5.8 6.4 7.9 7.7 4.2 5.0 5.5 4.5 10.0 6.6 9.4 8.4 26.4 18.8 5.5 9.8 14.4 13.3 5.7 5.6 3.8 CNOT8 "CAF1, CALIF, hCAF1, POP2" ENSG00000155508 "CCR4-NOT transcription complex subunit 8" Q9UFF9 5 154857553-154876792 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 124.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051398 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA051398: AB_2681468" "unprognostic (2.51e-1)" "unprognostic (4.26e-1)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.19e-1)" "unprognostic (3.62e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (2.80e-1)" "unprognostic (3.32e-3)" "unprognostic (2.19e-1)" "unprognostic (1.84e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.41e-4)" 62.3 39.9 35.5 38.4 36.5 118.3 46.5 37.0 43.3 42.0 47.4 41.2 33.5 33.8 36.9 26.6 29.5 29.9 26.1 34.5 35.1 28.9 29.2 49.3 58.7 37.7 36.5 30.2 22.8 40.0 18.3 42.2 38.4 28.8 46.6 25.0 35.1 28.1 21.7 41.7 37.0 32.0 38.8 49.8 30.8 39.0 39.4 69.7 35.6 26.0 53.1 35.9 29.8 40.6 33.4 36.6 64.3 71.2 60.6 55.1 49.1 51.4 55.9 54.8 83.9 47.7 73.5 58.9 61.8 43.6 43.2 36.2 45.2 62.3 61.8 29.3 47.4 49.8 55.7 42.9 38.5 114.3 86.5 37.5 54.5 49.0 42.2 57.0 68.5 81.5 44.6 43.1 58.4 39.4 100.3 118.5 35.6 39.4 21.4 85.7 55.2 61.6 43.7 44.5 50.9 74.4 68.0 54.2 64.9 35.7 50.4 92.7 52.9 57.1 35.3 32.2 34.0 41.4 56.8 91.0 40.1 89.5 36.1 277.6 127.3 269.5 72.3 91.6 79.8 79.9 87.4 86.9 133.2 81.5 115.5 84.6 126.2 91.7 74.6 70.5 107.8 169.6 35.5 36.5 37.0 43.3 34.5 35.1 37.7 36.5 38.4 38.8 39.4 40.6 29.1 19.2 39.7 14.7 39.8 31.9 16.5 37.4 23.9 12.1 23.4 17.5 12.8 12.8 31.5 16.5 0.0 32.5 37.5 17.8 17.6 25.1 124.5 21.5 36.7 35.1 27.6 37.0 15.2 20.2 44.6 28.8 18.8 23.0 17.7 33.2 28.2 13.8 27.1 18.5 11.4 32.1 26.4 49.1 47.1 54.6 45.4 32.5 28.4 26.2 51.2 12.1 23.7 15.1 23.3 31.5 18.7 38.0 21.3 24.2 22.6 13.0 19.9 8.0 6.6 19.6 25.7 29.6 23.1 21.1 41.8 22.8 38.1 29.8 27.7 27.2 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492982-149551471 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 847.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB016680: AB_1614518, HPA051334: AB_2681446" "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favorable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 77.0 67.6 49.0 67.3 53.9 210.8 97.8 60.0 52.7 67.9 61.5 83.2 56.6 73.7 60.2 142.4 56.6 79.7 87.6 48.6 55.9 50.3 68.2 69.6 60.0 61.3 56.4 53.2 55.0 99.4 48.8 71.7 56.6 88.3 68.2 57.6 71.3 69.2 104.1 121.4 63.1 82.9 57.9 60.7 73.5 45.6 57.8 81.0 76.9 59.5 81.8 94.8 82.3 66.3 154.4 106.4 151.0 144.1 143.6 191.4 185.0 189.7 176.8 146.0 153.5 194.1 187.0 71.6 221.3 183.3 140.7 153.9 101.2 292.5 184.1 124.6 78.0 96.9 96.6 87.8 143.1 163.9 148.4 158.5 313.4 148.1 269.0 163.9 184.7 137.2 102.2 116.0 140.7 104.4 152.2 66.6 71.4 167.6 247.3 129.0 96.1 98.9 112.3 248.3 123.5 110.5 151.1 193.3 200.8 135.6 194.1 134.4 164.6 168.6 83.6 118.2 197.1 117.0 149.2 100.6 169.2 95.6 216.9 106.0 72.6 66.6 47.5 68.9 51.6 50.2 58.1 49.7 80.0 39.9 61.4 55.2 61.1 63.7 67.8 47.4 76.7 94.7 49.0 53.9 60.0 52.7 48.6 55.9 61.3 56.4 56.6 57.9 57.8 66.3 169.7 147.4 176.7 137.1 101.8 684.5 583.1 270.0 187.8 135.8 257.0 158.4 63.5 90.1 298.1 115.8 64.6 171.2 135.6 126.8 92.0 167.1 95.7 195.8 193.5 191.1 129.9 146.7 108.4 184.1 223.7 159.8 124.4 285.2 117.6 114.0 216.4 108.9 136.1 151.4 115.4 141.9 154.6 167.8 311.5 87.5 104.1 183.8 152.9 119.0 156.6 156.9 108.1 168.4 198.1 197.2 113.9 111.7 105.4 368.6 120.4 102.8 276.7 109.6 157.8 190.2 216.1 181.9 88.9 272.4 847.7 350.9 133.5 177.0 115.7 485.2 CSRNP1 "AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1" ENSG00000144655 "Cysteine and serine rich nuclear protein 1" Q96S65 3 39141855-39154562 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 193.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045207, HPA058463" Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA045207: AB_10967202, HPA058463: AB_2683726" "unprognostic (2.90e-2)" "unprognostic (6.89e-2)" "unprognostic (3.00e-1)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (1.46e-1)" "unprognostic (3.78e-2)" "unprognostic (1.90e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.07e-4)" "prognostic unfavorable (6.47e-4)" "unprognostic (2.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.51e-1)" 88.9 55.8 13.6 34.0 13.7 193.1 51.7 17.2 22.5 34.7 15.4 35.6 12.0 30.2 6.4 61.7 79.8 67.5 49.9 12.8 18.0 29.2 67.3 80.8 14.9 21.3 16.2 41.5 39.4 23.5 43.3 25.0 15.7 32.7 15.4 5.8 21.3 18.5 36.9 57.1 26.4 64.1 18.3 20.3 48.0 14.7 17.1 34.9 33.8 19.0 8.7 51.6 27.7 15.4 4.4 9.7 2.5 4.8 4.7 4.9 7.8 15.9 22.1 13.0 10.6 13.7 4.0 14.4 3.3 12.1 9.3 4.9 3.0 21.0 6.4 21.6 4.0 16.4 8.0 10.5 5.8 4.1 15.7 2.3 11.3 20.4 3.2 11.6 17.8 3.9 12.7 24.9 10.7 13.9 0.8 6.7 11.4 7.4 8.1 6.8 10.4 23.7 10.3 15.9 7.0 1.1 8.7 64.2 5.5 14.5 7.2 7.5 9.0 6.6 28.2 5.6 11.9 6.3 5.8 6.6 14.4 5.2 8.4 0.1 3.0 3.8 1.7 5.9 2.1 3.6 1.6 2.0 3.3 3.7 2.0 1.3 17.1 2.6 11.0 4.2 2.7 2.3 13.6 13.7 17.2 22.5 12.8 18.0 21.3 16.2 15.7 18.3 17.1 15.4 200.8 48.1 66.3 6.8 75.0 103.2 88.1 40.2 153.1 1.4 121.1 95.8 15.8 37.1 31.2 11.0 0.0 19.7 86.3 77.3 9.8 37.6 54.4 119.6 65.2 92.8 59.3 13.2 3.5 38.5 43.0 98.1 75.4 199.4 96.5 4.2 73.9 40.7 38.7 0.0 1.5 54.7 22.4 36.7 165.2 46.8 1.5 94.5 69.4 4.7 14.8 7.6 7.2 1.5 1.3 49.2 60.9 4.1 74.3 49.4 54.1 6.0 21.0 1.7 13.1 154.4 103.9 0.6 4.7 85.7 79.6 90.7 132.4 8.9 38.0 38.9 CXorf56 FLJ22965 ENSG00000018610 "Chromosome X open reading frame 56" Q9H5V9 X 119538149-119565409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038245, HPA038617, HPA064831" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Centrosome "HPA038245: AB_10672407, HPA038617: AB_10674691, HPA064831: AB_2685364" "prognostic unfavorable (3.45e-4)" "unprognostic (3.88e-3)" "unprognostic (7.82e-2)" "unprognostic (1.03e-3)" "unprognostic (8.92e-2)" "unprognostic (7.74e-3)" "unprognostic (6.38e-3)" "unprognostic (3.89e-2)" "unprognostic (4.11e-1)" "unprognostic (1.51e-2)" "unprognostic (9.63e-3)" "unprognostic (1.68e-3)" "unprognostic (9.26e-3)" "unprognostic (4.68e-3)" "unprognostic (1.45e-2)" "unprognostic (5.51e-2)" "unprognostic (1.90e-1)" 11.6 9.8 8.2 7.6 8.6 16.2 12.5 8.3 9.2 10.1 7.1 10.0 7.7 11.6 9.0 9.4 9.9 6.1 10.5 8.2 9.4 11.6 8.8 8.8 10.7 7.9 7.9 13.7 8.8 11.7 7.2 10.2 8.7 8.8 8.7 11.5 9.9 8.8 13.0 12.3 9.0 8.7 8.0 9.8 9.0 6.7 9.3 11.5 11.8 13.2 11.6 9.3 9.0 9.7 27.3 26.2 16.8 19.8 17.9 12.5 22.9 17.1 15.4 22.3 20.7 23.4 26.7 41.3 43.2 16.9 53.9 16.9 40.1 21.0 30.5 24.8 30.3 14.9 25.2 16.2 13.8 41.3 22.1 14.7 17.9 29.1 24.0 14.2 16.3 24.0 32.2 25.4 11.1 40.5 24.8 24.7 27.3 33.4 28.4 23.9 19.0 29.9 15.8 19.8 12.1 22.0 35.9 19.3 25.3 18.0 15.0 17.9 20.4 16.9 12.0 31.2 39.6 21.9 42.7 42.0 14.2 39.7 20.3 5.0 10.3 13.9 9.0 12.6 8.2 10.9 7.7 9.5 9.5 15.6 7.9 7.7 4.8 6.4 11.9 8.7 10.4 9.4 8.2 8.6 8.3 9.2 8.2 9.4 7.9 7.9 8.7 8.0 9.3 9.7 2.6 3.2 13.9 1.6 10.6 6.2 8.0 4.8 5.7 15.7 4.8 5.0 13.4 7.2 5.4 3.7 6.2 20.5 3.5 8.3 21.5 9.2 1.3 8.7 10.3 7.5 8.5 10.3 9.4 6.6 20.1 5.3 4.1 10.5 17.2 7.7 6.8 6.4 10.1 8.4 10.8 6.0 8.2 12.9 8.3 1.2 9.6 6.5 12.4 2.8 17.1 15.8 6.2 7.5 6.8 6.8 6.5 11.3 7.8 5.2 9.8 13.2 6.8 11.3 13.1 9.5 11.1 5.4 10.0 6.5 5.8 35.6 9.2 7.6 7.9 8.6 CXXC1 "CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1" ENSG00000154832 "CXXC finger protein 1" Q9P0U4 18 50282343-50287839 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044511 Supported Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA044511: AB_10963081" "unprognostic (4.47e-2)" "unprognostic (1.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.18e-6)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (5.08e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.10e-2)" "unprognostic (1.00e-1)" "unprognostic (3.83e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-2)" 18.1 26.7 24.4 22.8 25.4 45.9 19.3 29.8 30.5 28.0 25.9 23.6 27.3 23.3 10.3 23.6 24.9 17.5 19.9 24.6 24.6 25.5 24.5 19.2 34.3 24.6 24.5 30.0 38.7 20.3 21.0 16.0 25.2 24.4 15.9 13.6 32.4 21.4 20.2 29.5 23.5 14.9 22.8 29.6 25.7 22.8 25.0 30.7 23.2 13.1 21.1 25.6 23.7 26.3 24.6 31.9 33.4 46.9 28.9 16.2 46.9 34.3 28.4 38.5 32.1 21.6 19.6 60.2 17.6 22.0 18.5 44.6 51.6 37.0 21.7 51.9 33.0 57.9 42.3 39.5 19.6 126.4 68.7 19.5 32.9 38.0 51.0 26.0 25.0 58.8 29.9 63.8 27.3 37.7 71.6 67.7 47.8 16.9 22.4 74.5 26.9 56.5 26.8 13.9 48.4 47.2 18.0 17.8 21.6 21.2 22.9 56.9 29.2 45.1 28.4 18.4 29.6 119.1 87.7 52.5 28.4 58.6 35.5 24.7 18.8 34.0 24.0 22.0 25.0 26.9 21.6 23.6 21.9 27.5 23.1 18.9 8.1 22.6 18.8 15.5 26.4 20.6 24.4 25.4 29.8 30.5 24.6 24.6 24.6 24.5 25.2 22.8 25.0 26.3 18.1 19.2 27.4 21.9 27.8 26.8 13.1 21.7 21.1 15.3 20.2 17.4 7.3 18.6 23.8 18.4 14.6 34.5 23.7 31.4 13.7 19.4 13.8 20.9 13.8 18.3 35.3 14.9 10.2 21.8 39.2 16.6 33.1 17.6 8.2 20.5 16.8 15.3 22.0 8.4 8.7 25.0 26.4 20.2 17.2 9.8 19.9 21.0 8.8 7.5 21.3 19.3 43.3 9.5 9.4 21.8 26.1 19.5 41.5 13.3 26.5 14.9 21.4 13.5 6.6 19.5 16.9 49.4 22.1 24.5 30.1 37.1 27.7 18.3 26.5 12.0 CYB5R4 "b5+b5R, dJ676J13.1, NCB5OR" ENSG00000065615 "Cytochrome b5 reductase 4" Q7L1T6 6 83859656-83967423 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 179.2;Late spermatids: 364.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 199.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 75.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018992 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA018992: AB_1847371" "unprognostic (4.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-2)" "unprognostic (1.72e-1)" "unprognostic (3.25e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (4.77e-1)" "unprognostic (6.77e-2)" "unprognostic (1.39e-2)" "unprognostic (5.44e-1)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.15e-1)" "unprognostic (8.15e-2)" 5.1 3.1 4.0 12.0 4.4 17.0 3.6 9.8 6.0 2.4 1.0 7.1 6.5 3.0 3.2 4.5 2.3 3.2 4.2 3.7 4.0 4.0 3.9 5.1 9.8 4.0 2.9 2.5 5.6 2.6 1.9 3.4 4.7 3.0 5.0 5.4 3.6 2.5 6.3 3.1 7.3 3.5 2.6 8.8 7.0 12.1 4.1 6.6 2.3 4.4 7.1 5.3 3.1 8.2 10.6 9.2 6.5 8.1 3.4 4.6 12.0 7.0 10.9 10.4 14.8 12.7 6.8 19.9 10.8 4.7 27.7 8.8 6.1 10.1 7.5 75.1 14.2 47.0 5.2 7.0 6.4 28.5 40.0 6.1 2.8 7.3 7.1 4.2 5.8 17.2 17.1 14.1 7.7 4.5 7.4 9.6 3.6 8.5 8.9 12.3 23.3 6.9 5.6 10.9 17.4 9.6 8.7 8.2 9.5 3.9 5.0 16.3 7.2 10.2 8.5 21.2 22.4 16.4 27.0 10.7 11.8 19.2 11.7 104.0 59.0 177.3 16.6 50.4 13.6 27.4 14.6 15.0 46.6 26.9 9.4 14.7 199.1 14.2 58.1 19.7 23.9 29.3 4.0 4.4 9.8 6.0 3.7 4.0 4.0 2.9 4.7 2.6 4.1 8.2 9.9 6.4 13.9 31.3 46.5 11.1 14.4 17.5 8.0 15.5 8.5 5.8 15.4 11.5 18.3 7.3 16.7 5.9 31.3 22.0 11.7 25.7 179.2 8.4 9.2 9.7 16.2 10.1 46.6 25.1 20.5 9.2 21.9 13.5 25.3 6.0 4.2 11.3 45.1 13.5 51.0 14.8 28.5 56.6 49.7 364.5 8.4 59.4 16.0 37.5 74.4 5.8 47.4 48.7 85.8 28.4 17.3 7.5 27.1 13.6 15.7 21.6 14.8 18.7 6.6 16.9 13.1 25.7 27.3 12.5 14.8 11.5 28.2 8.3 13.3 23.6 DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA045940: AB_2679506" "unprognostic (1.00e-2)" "unprognostic (3.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "unprognostic (5.47e-2)" "unprognostic (4.75e-3)" "unprognostic (8.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.42e-1)" "prognostic favorable (3.94e-9)" "unprognostic (1.79e-1)" "unprognostic (2.40e-1)" "unprognostic (3.04e-1)" "unprognostic (5.84e-3)" 136.4 115.7 112.2 187.5 125.3 613.5 154.0 136.6 124.4 150.5 109.8 206.2 194.9 131.6 122.5 129.9 180.5 168.0 202.1 105.1 125.9 251.4 198.4 193.2 220.6 132.7 119.8 114.1 116.5 227.3 30.7 79.5 134.4 152.8 215.5 75.2 140.7 171.8 113.5 121.4 200.5 148.4 129.8 224.3 174.3 52.7 116.5 213.2 209.8 106.7 241.5 190.3 76.3 151.5 159.8 209.0 95.4 92.2 201.1 171.5 57.6 104.6 208.9 187.7 162.8 155.9 239.0 153.2 262.2 209.9 130.0 147.8 134.2 178.4 189.2 167.3 160.2 227.1 129.7 91.0 216.4 265.5 350.2 220.5 252.1 175.3 147.2 207.2 234.8 118.8 141.6 303.1 155.4 252.6 219.8 145.6 19.6 109.2 58.7 123.2 144.7 165.3 244.9 260.2 103.3 101.0 159.3 137.9 121.3 56.7 190.5 382.7 195.7 111.1 102.4 136.9 132.6 231.5 237.5 158.6 161.2 175.0 66.9 2018.1 2144.1 3354.3 1055.9 1770.0 979.3 1090.7 962.8 1037.9 1354.1 1068.7 1063.1 918.3 3499.5 1045.4 1727.1 875.9 1420.3 4885.3 112.2 125.3 136.6 124.4 105.1 125.9 132.7 119.8 134.4 129.8 116.5 151.5 116.7 144.2 205.1 19.6 271.9 113.8 201.2 144.6 167.9 50.6 127.7 88.5 114.3 165.8 127.9 235.4 58.4 55.8 167.4 337.2 266.1 158.6 28.1 115.1 87.2 138.3 126.3 155.6 16.8 194.7 53.5 108.0 171.8 142.1 182.2 72.2 157.1 177.1 209.4 67.3 16.8 230.6 140.4 444.4 214.2 85.6 117.4 282.0 135.2 19.7 324.4 88.7 221.4 15.6 43.9 198.0 275.8 95.5 169.5 179.9 233.3 292.7 155.9 55.2 46.0 63.2 130.4 39.4 35.4 153.5 133.3 124.9 249.6 72.8 182.4 268.7 DCTN5 "MGC3248, p25" ENSG00000166847 "Dynactin subunit 5" Q9BTE1 16 23641466-23677472 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042003, HPA063710" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA042003: AB_10796468, HPA063710: AB_2685101" "unprognostic (5.90e-3)" "unprognostic (3.38e-1)" "unprognostic (1.77e-1)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (6.36e-2)" "unprognostic (6.78e-2)" "unprognostic (9.28e-2)" "prognostic favorable (4.48e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.59e-2)" "unprognostic (9.55e-2)" 13.9 11.3 14.6 18.1 18.1 41.5 14.2 10.4 18.3 13.6 3.8 19.2 20.8 14.8 12.0 25.2 13.6 14.2 14.7 17.2 13.0 21.0 10.7 14.0 22.1 11.4 13.6 12.0 15.9 19.8 8.5 20.9 11.1 14.1 24.9 21.5 12.8 14.0 13.9 14.1 22.2 21.7 11.4 15.1 16.7 20.6 12.8 20.9 18.8 14.2 32.2 20.6 10.9 12.9 30.0 58.5 56.0 46.9 39.0 28.9 39.2 51.9 32.1 32.9 39.3 66.5 40.3 42.1 41.2 54.8 34.6 30.6 93.4 50.2 40.5 48.1 37.1 51.9 67.2 93.9 26.5 63.7 38.4 24.3 35.3 40.5 42.8 36.5 52.8 52.0 100.7 31.6 53.3 82.4 49.4 18.4 66.3 43.3 25.5 59.8 48.6 45.9 26.2 62.6 46.8 48.5 45.6 36.7 30.5 49.0 51.2 53.2 71.8 44.0 20.0 34.9 36.6 42.6 68.6 66.2 42.0 31.4 48.8 14.3 16.6 20.3 15.5 14.0 17.1 13.9 14.2 17.0 17.5 10.5 12.0 14.3 7.3 22.0 22.0 12.4 19.0 17.2 14.6 18.1 10.4 18.3 17.2 13.0 11.4 13.6 11.1 11.4 12.8 12.9 19.7 16.0 26.2 12.1 19.1 14.7 14.5 12.9 22.8 52.1 15.5 14.5 27.1 15.7 15.6 20.2 91.8 32.9 16.1 36.2 11.7 23.8 23.2 11.9 22.4 22.5 22.1 27.6 13.4 25.2 36.3 16.3 20.9 20.8 27.8 37.3 17.2 14.2 28.4 52.2 13.2 18.9 12.2 19.1 11.4 23.4 13.1 17.1 7.2 6.5 34.4 32.3 30.9 11.1 12.0 45.7 19.4 18.0 17.4 14.4 31.9 23.3 11.2 45.0 13.1 22.4 18.1 70.4 30.6 20.9 14.2 48.2 18.7 17.9 26.2 22.0 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Supported Nucleoplasm,Nucleoli No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 5.9 6.4 6.0 10.2 6.8 29.2 7.2 6.9 7.3 10.7 7.1 9.6 8.0 7.5 4.3 9.5 8.0 5.9 5.3 6.0 6.1 9.2 9.3 6.1 13.2 6.9 6.4 11.0 17.5 5.8 9.4 5.4 6.9 10.0 10.1 6.6 8.6 5.3 10.6 16.7 13.4 3.6 6.1 13.8 9.6 8.8 6.7 24.0 8.0 6.6 11.1 6.9 9.8 6.9 36.5 35.0 42.2 34.5 5.8 11.0 58.7 21.8 10.4 25.2 28.5 44.1 58.6 49.2 23.9 10.8 23.6 35.0 31.7 28.9 21.3 43.4 66.6 47.4 71.0 25.4 2.1 37.4 35.0 11.9 13.0 32.6 24.8 16.9 12.6 55.2 26.6 103.3 17.6 30.9 64.5 60.7 84.0 39.9 19.5 55.0 53.3 66.2 13.3 38.5 30.2 21.7 23.4 33.2 10.4 65.0 27.3 25.5 8.2 22.0 42.1 42.2 40.0 39.4 29.6 95.3 24.6 32.5 20.3 0.0 1.3 0.8 2.0 1.2 1.5 2.5 1.9 1.5 1.5 2.6 2.0 2.6 0.5 2.2 4.4 2.4 2.0 1.3 6.0 6.8 6.9 7.3 6.0 6.1 6.9 6.4 6.9 6.1 6.7 6.9 10.1 3.2 9.5 1.6 9.0 6.0 4.0 6.0 2.2 9.4 8.3 7.1 2.5 4.3 6.0 0.0 14.6 7.6 8.8 7.8 0.0 2.0 1.7 5.5 8.9 5.4 0.0 15.3 2.5 3.3 7.5 5.7 9.7 7.4 5.7 15.6 6.1 7.7 5.2 8.4 3.6 6.5 10.2 4.1 5.4 1.3 7.2 4.4 7.2 3.7 3.5 2.7 4.1 1.5 1.7 3.2 2.7 4.5 17.2 6.0 2.3 1.4 6.7 25.8 0.0 4.9 4.8 5.3 18.0 5.5 6.5 2.6 8.4 4.1 9.5 5.1 DDX27 "dJ686N3.1, DRS1" ENSG00000124228 "DEAD-box helicase 27" 20 49219347-49244077 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 176.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047087, HPA053455" Approved Approved Nucleoli NA No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoli "HPA047087: AB_10964059, HPA053455: " "unprognostic (4.47e-2)" "unprognostic (2.41e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (2.82e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (6.70e-7)" "unprognostic (2.28e-1)" "unprognostic (9.53e-2)" "unprognostic (2.74e-1)" "unprognostic (7.18e-2)" "unprognostic (5.84e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.26e-1)" "unprognostic (4.32e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" 20.4 20.9 15.8 25.8 16.0 46.5 19.5 19.5 20.5 20.4 15.5 21.0 22.6 21.3 15.1 20.7 17.5 19.4 15.6 15.9 17.2 20.7 17.2 18.0 34.3 16.7 16.8 27.3 24.5 20.4 15.4 20.3 17.1 18.7 20.8 10.9 20.5 15.9 24.8 25.0 26.8 18.5 15.5 24.7 20.4 24.4 16.9 29.9 19.1 16.7 35.6 27.6 18.0 17.7 75.2 69.7 34.9 27.4 38.3 35.1 99.6 48.6 39.9 149.7 69.3 228.3 82.2 88.8 88.1 40.0 129.7 103.7 79.1 77.8 111.0 31.6 46.1 67.6 58.4 113.2 55.7 86.1 76.0 37.0 90.2 87.5 67.3 34.0 25.1 67.5 93.7 47.6 49.8 50.6 90.9 114.0 66.9 91.3 89.2 77.6 87.0 82.4 54.9 57.1 45.8 54.0 135.8 194.2 83.0 48.5 102.5 98.5 31.0 96.0 84.3 80.8 102.9 54.1 62.6 115.6 61.4 67.5 63.4 21.1 32.8 39.4 34.2 36.8 36.0 48.6 32.3 31.5 39.2 50.8 41.1 31.4 13.6 32.6 45.7 45.4 46.3 33.9 15.8 16.0 19.5 20.5 15.9 17.2 16.7 16.8 17.1 15.5 16.9 17.7 33.9 28.9 44.7 7.8 93.3 35.7 55.1 41.8 30.7 25.7 28.0 32.3 25.7 21.5 45.7 33.1 14.6 58.1 114.0 45.8 19.6 54.0 176.7 45.4 58.4 28.6 31.0 41.2 10.0 43.6 50.5 44.7 27.0 67.4 113.4 42.2 21.0 23.1 33.7 28.6 9.1 44.3 20.3 25.1 54.1 145.7 39.7 48.5 19.6 5.6 42.9 29.9 63.8 4.5 5.4 55.4 44.6 33.8 57.9 38.2 55.0 44.9 35.4 29.4 26.3 52.4 41.7 69.1 56.6 29.5 32.1 74.6 67.9 37.3 50.7 42.1 DKC1 "Cbf5, DKC, dyskerin, NAP57, NOLA4, XAP101" ENSG00000130826 "Dyskerin pseudouridine synthase 1" O60832 X 154762742-154777689 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Isomerase, Ribonucleoprotein, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 707.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000166, HPA000447, HPA001022, CAB033086" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 34000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" Nucleoplasm "CAB033086: AB_2091314, HPA000166: AB_1078669, HPA000447: AB_1078667, HPA001022: AB_2666175" "unprognostic (9.87e-3)" "unprognostic (1.14e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (2.86e-1)" "prognostic unfavorable (2.94e-4)" "prognostic unfavorable (1.39e-5)" "unprognostic (7.02e-2)" "prognostic unfavorable (9.13e-4)" "unprognostic (2.53e-2)" "unprognostic (2.35e-2)" "unprognostic (2.63e-2)" "prognostic unfavorable (1.46e-9)" "unprognostic (5.28e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-1)" "unprognostic (2.55e-1)" 23.5 20.4 17.1 29.9 18.1 68.8 35.3 18.3 20.5 21.3 18.9 28.5 24.2 23.2 22.3 36.4 24.4 15.3 19.4 17.0 18.4 21.7 22.6 16.5 40.2 17.9 18.2 30.8 32.6 26.5 17.6 23.2 18.8 22.2 34.8 19.8 22.0 18.9 31.2 30.6 21.3 22.8 18.0 25.7 21.5 25.3 18.1 39.4 27.8 23.2 47.8 36.8 23.8 19.7 236.5 129.3 77.4 111.4 47.2 48.2 114.9 87.2 60.5 127.2 118.9 164.3 114.2 447.2 221.3 74.7 119.4 123.5 239.6 144.8 189.3 108.8 132.9 223.4 131.1 143.3 66.9 304.6 131.2 46.3 135.6 141.1 320.8 46.6 89.7 146.2 210.1 108.0 88.0 137.7 201.5 233.7 130.2 234.0 158.8 177.1 174.1 230.3 80.4 132.0 170.0 84.4 77.8 133.3 122.7 75.0 68.1 120.8 70.8 91.4 138.2 119.3 292.6 199.8 290.5 707.7 62.2 316.5 102.0 10.8 25.0 33.1 38.6 30.1 48.8 44.2 31.1 41.6 35.5 31.3 40.7 39.1 7.4 41.2 31.2 25.5 26.5 30.3 17.1 18.1 18.3 20.5 17.0 18.4 17.9 18.2 18.8 18.0 18.1 19.7 21.6 25.6 32.3 5.9 47.6 99.7 76.2 45.4 60.3 31.6 39.2 34.0 32.0 25.8 35.2 25.8 14.6 56.6 34.8 17.7 41.1 62.8 2.7 22.4 39.8 39.7 34.1 84.1 6.4 45.3 74.8 36.4 23.0 24.1 56.8 70.0 13.6 26.0 44.5 23.5 7.1 35.9 54.9 21.6 36.4 7.9 25.7 25.8 49.8 7.5 36.4 34.8 29.9 7.5 7.7 47.3 14.8 28.6 45.1 131.2 9.5 25.6 26.7 28.5 13.1 37.8 42.6 41.0 87.2 69.9 98.3 34.2 35.9 59.6 49.9 57.9 DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol NA NA 3200000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA035780: AB_2674778, HPA035781: AB_10669529" "unprognostic (5.74e-2)" "unprognostic (1.16e-3)" "unprognostic (2.62e-3)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-3)" "unprognostic (1.67e-3)" "unprognostic (1.25e-3)" "unprognostic (1.73e-2)" "unprognostic (9.87e-2)" "unprognostic (1.02e-2)" "unprognostic (3.87e-1)" "unprognostic (5.85e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (3.43e-1)" "unprognostic (5.66e-2)" 11.6 17.5 8.2 21.4 9.1 20.7 11.2 10.2 10.4 11.0 5.4 30.2 24.8 11.7 7.8 23.5 9.8 14.5 10.3 8.4 8.9 17.1 18.6 14.3 21.8 10.2 8.8 6.8 17.3 11.9 8.7 14.3 10.8 14.4 26.3 15.9 18.8 12.9 26.5 13.6 20.5 16.2 8.6 15.4 19.2 9.8 10.2 18.6 11.7 7.4 23.3 17.3 13.5 9.9 84.1 71.6 32.5 36.3 26.4 28.3 50.4 46.5 61.8 61.4 40.7 90.8 68.4 48.7 154.0 52.9 52.2 73.6 52.1 57.0 39.4 92.5 23.8 63.1 32.1 54.2 40.7 77.6 101.1 40.5 54.5 46.2 22.8 26.5 47.8 50.1 45.1 28.2 56.7 95.3 91.0 78.7 55.5 82.0 43.2 63.1 32.7 79.6 52.6 71.7 61.1 52.2 39.7 45.6 62.5 30.3 70.8 44.7 50.1 36.5 39.4 40.7 46.2 23.3 46.6 56.6 48.5 36.5 45.9 20.7 18.8 21.3 21.4 40.0 13.3 11.5 15.8 17.7 32.3 11.1 9.4 13.9 3.2 30.8 27.9 22.5 29.6 17.7 8.2 9.1 10.2 10.4 8.4 8.9 10.2 8.8 10.8 8.6 10.2 9.9 5.8 16.0 13.2 6.8 11.6 6.0 17.4 34.8 8.6 11.4 7.1 3.8 3.0 10.0 27.0 23.9 10.4 46.9 11.5 41.6 13.7 45.6 24.6 8.7 6.2 10.5 18.6 3.4 3.4 61.3 34.2 7.4 29.0 11.5 1.3 9.9 3.6 14.7 37.4 6.7 4.0 19.5 63.1 7.9 9.0 7.0 2.1 10.8 16.0 3.7 31.3 21.6 18.6 4.5 5.6 40.8 25.2 5.3 15.7 11.0 26.4 28.7 17.3 72.9 13.1 4.4 16.2 8.8 20.7 14.4 6.0 36.0 13.1 20.1 29.5 19.5 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DUSP12 "DUSP1, YVH1" ENSG00000081721 "Dual specificity phosphatase 12" Q9UNI6 1 161749758-161757238 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008840 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA008840: AB_1847884" "unprognostic (3.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (2.11e-1)" "unprognostic (4.04e-2)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.25e-3)" "unprognostic (9.52e-2)" "unprognostic (2.42e-3)" "prognostic unfavorable (1.55e-7)" "unprognostic (1.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" 13.3 9.6 12.1 9.1 12.5 30.9 14.1 14.3 14.6 13.8 12.1 12.9 7.6 14.3 8.9 10.3 12.5 6.7 9.4 12.0 12.4 14.4 9.4 11.4 13.8 12.2 12.2 13.6 13.6 8.2 9.5 11.2 12.3 11.0 10.5 13.2 10.9 9.5 7.4 10.9 12.4 11.0 12.3 14.1 11.5 6.7 12.0 11.7 12.1 7.3 13.0 13.1 11.5 13.3 32.6 28.2 33.1 21.7 17.2 18.5 30.4 25.9 33.7 39.2 29.9 42.1 28.2 19.9 25.7 31.9 24.4 22.7 26.0 32.0 38.0 25.5 22.0 17.8 27.7 28.4 36.4 38.6 17.1 25.4 34.6 34.1 61.0 22.2 27.6 27.2 31.7 20.9 28.3 30.0 22.7 43.2 52.1 35.2 43.1 32.2 32.0 32.9 22.2 39.3 20.6 43.6 21.9 36.2 44.1 36.2 31.3 43.6 19.3 33.3 30.8 26.3 55.6 35.3 31.0 47.0 20.3 38.1 33.3 32.0 16.9 13.7 18.4 19.5 22.9 19.2 20.8 17.8 22.0 20.0 19.6 21.8 6.8 28.4 12.2 10.0 19.5 12.9 12.1 12.5 14.3 14.6 12.0 12.4 12.2 12.2 12.3 12.3 12.0 13.3 22.9 19.2 12.8 8.1 25.5 13.6 14.4 25.9 25.6 15.9 13.4 16.1 5.0 8.6 15.6 7.3 8.4 21.7 26.4 4.8 21.5 22.2 4.2 7.4 13.7 18.4 11.3 16.2 11.9 24.3 22.7 17.3 11.7 7.2 18.3 18.7 18.5 8.2 20.5 10.1 14.8 9.8 8.2 20.6 16.2 1.2 8.7 15.4 10.6 10.3 22.1 15.8 33.0 12.1 14.4 21.2 6.5 17.7 27.5 17.1 8.6 18.5 7.0 19.6 0.0 13.2 24.5 13.9 12.6 18.2 13.1 17.6 23.5 16.4 12.1 12.0 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143169-96145440 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.5" "Cell type enhanced" "Detected in many" "dendritic cells: 919.7;Glandular and luminal cells: 321.1;Langerhans cells: 924.0;Macrophages: 353.9;T-cells: 764.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 55.0" "Immune cell enhanced" "Detected in all" "gdT-cell: 199.3" "Group enriched" "Detected in all" 10 "NK-cells: 148.1;T-cells: 199.3" "Cell line enhanced" "Detected in many" "Daudi: 30.4;HeLa: 29.7;JURKAT: 27.6;Karpas-707: 33.8;NB-4: 29.1;RT4: 34.2;SCLC-21H: 29.6;U-698: 43.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 17.0 6.0 7.6 18.6 11.6 129.5 5.5 7.5 55.0 8.1 9.2 4.5 1.6 7.0 7.7 6.8 7.6 12.5 19.5 13.4 6.2 12.7 7.5 18.2 47.1 8.0 6.3 7.8 2.3 1.7 35.1 1.3 6.7 17.6 2.0 0.4 3.9 61.5 2.8 26.0 11.8 3.4 6.7 42.0 7.4 3.6 6.9 47.3 6.7 3.7 24.6 39.5 9.0 9.3 3.2 0.0 0.2 0.2 0.4 0.5 4.4 3.7 0.0 5.3 5.1 8.9 0.6 30.4 10.6 4.1 0.0 2.2 7.5 0.0 1.0 0.5 0.0 0.7 29.7 0.0 1.9 12.8 2.6 0.9 2.0 0.9 0.0 0.1 0.0 27.6 0.0 33.8 0.2 5.2 25.5 29.1 6.5 0.8 10.6 0.0 0.4 24.3 0.2 34.2 29.6 1.5 1.4 0.3 5.6 0.0 2.0 14.4 0.1 0.0 7.9 0.0 1.7 2.3 3.9 43.2 0.0 13.9 0.3 2.3 4.3 1.0 199.3 10.5 95.4 17.5 46.7 176.2 10.7 13.9 32.0 99.3 6.1 148.1 9.1 3.0 16.1 40.5 7.6 11.6 7.5 55.0 13.4 6.2 8.0 6.3 6.7 6.7 6.9 9.3 50.8 0.0 7.7 0.7 303.7 96.7 155.0 31.3 70.6 27.8 65.8 72.0 37.8 2.8 12.0 9.2 22.9 0.9 919.7 20.4 1.9 0.9 0.9 115.6 62.7 28.7 87.8 50.5 5.2 1.4 1.7 22.8 86.6 321.1 104.3 7.4 12.8 3.9 80.2 0.0 1.4 37.5 8.2 40.4 924.0 1.4 1.8 353.9 144.1 1.9 3.4 1.5 90.6 1.0 0.5 1.0 2.5 1.9 268.5 70.4 1.6 1.4 2.7 3.6 0.0 14.7 26.6 0.6 4.8 50.4 109.7 1.6 764.7 3.0 51.6 41.1 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 156.7;Inhibitory neurons: 158.4;Microglial cells: 176.1;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 157.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 23.1 20.4 17.8 22.5 19.9 71.4 22.3 29.9 20.7 23.9 22.2 22.2 18.7 26.6 22.0 18.8 22.6 19.9 28.9 21.3 19.2 19.9 19.8 22.3 30.1 12.1 14.7 29.6 21.5 27.8 20.2 23.0 13.3 18.8 21.6 27.8 21.3 19.2 49.4 24.2 21.7 24.1 12.8 30.4 22.8 29.9 18.6 45.8 25.7 45.2 26.7 24.3 21.1 20.9 23.5 18.2 36.3 25.6 17.1 18.8 32.7 20.8 26.0 20.3 22.0 25.7 19.7 31.7 13.8 37.0 27.1 15.8 27.3 21.2 24.4 49.7 11.6 93.6 30.9 16.1 26.5 36.9 32.3 18.7 24.3 26.5 41.2 23.5 22.3 44.2 36.4 70.4 22.2 23.6 49.3 25.9 38.5 24.1 10.8 62.8 19.7 29.6 22.3 30.4 36.5 20.4 47.1 31.6 33.2 12.2 29.9 34.8 27.8 27.6 8.3 17.2 17.4 47.7 41.6 44.9 22.0 41.8 30.7 3.1 0.5 0.8 1.2 0.8 0.7 1.1 1.3 1.0 0.7 1.0 1.4 1.3 2.3 0.5 1.1 1.3 1.3 0.3 17.8 19.9 29.9 20.7 21.3 19.2 12.1 14.7 13.3 12.8 18.6 20.9 36.8 19.2 25.5 114.3 28.8 37.5 24.1 15.7 18.2 32.7 28.3 18.0 73.0 20.0 23.0 11.0 27.1 10.3 43.0 30.1 0.0 13.5 29.7 44.2 39.3 31.9 21.4 26.1 156.7 14.6 12.4 25.2 21.4 71.4 24.7 35.9 27.1 18.1 15.8 47.1 158.4 18.8 14.2 25.0 27.7 22.2 16.1 32.4 24.9 176.1 18.8 16.4 21.6 158.3 157.2 21.2 22.4 19.5 33.8 29.8 17.1 9.9 27.9 21.8 13.1 38.4 32.5 15.3 24.7 24.6 31.7 15.3 36.8 21.3 19.3 37.2 E2F2 E2F-2 ENSG00000007968 "E2F transcription factor 2" Q14209 1 23506438-23531233 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 25.1;esophagus: 8.7;lymphoid tissue: 15.8" "Group enriched" "Detected in many" 4 "Early spermatids: 50.2;Erythroid cells: 45.7;Late spermatids: 110.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 46.7;Karpas-707: 38.9;U-266/84: 37.2;U-698: 38.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB016313 Uncertain NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "CAB016313: AB_2096794" "unprognostic (3.14e-2)" "unprognostic (5.74e-3)" "unprognostic (1.31e-3)" "unprognostic (4.18e-2)" "unprognostic (8.54e-2)" "unprognostic (1.70e-3)" "unprognostic (6.43e-6)" "unprognostic (7.83e-3)" "unprognostic (1.53e-2)" "unprognostic (7.33e-2)" "unprognostic (1.51e-3)" "unprognostic (1.86e-2)" "unprognostic (0.00e+0)" "unprognostic (1.00e-3)" "unprognostic (2.82e-1)" "unprognostic (8.67e-3)" "unprognostic (1.84e-1)" 0.2 0.2 0.0 1.8 0.0 25.1 0.1 0.1 0.1 0.9 0.1 3.4 1.5 0.1 0.0 8.7 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.8 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.1 2.1 0.0 0.8 0.0 0.1 3.5 2.1 0.3 0.0 5.1 0.7 3.6 0.1 15.8 0.2 0.0 3.7 0.3 1.9 0.1 5.4 3.9 6.4 10.2 0.2 0.2 4.5 2.5 1.2 2.4 3.1 2.5 3.1 46.7 3.0 1.3 1.1 10.6 12.9 0.6 2.2 11.8 4.2 7.4 10.7 2.8 0.0 5.4 9.3 0.0 0.1 1.7 0.2 0.3 0.7 21.4 5.8 38.9 1.1 3.2 24.3 5.0 1.4 5.8 1.9 26.4 13.7 15.7 0.9 1.4 8.3 11.6 4.3 5.4 1.3 0.8 4.0 3.9 0.5 2.2 6.1 7.0 3.6 28.5 37.2 38.0 2.1 5.8 4.3 4.1 0.2 0.8 0.0 0.6 0.0 0.4 0.3 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.9 0.4 1.3 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 0.8 0.2 0.2 1.8 0.0 1.0 1.3 0.6 0.0 0.3 1.8 0.0 3.4 0.7 14.5 0.0 0.1 50.2 0.3 0.3 0.6 1.2 45.7 0.1 0.0 4.8 1.1 3.1 1.1 0.0 4.2 0.4 0.4 2.3 0.0 0.1 5.9 0.0 3.1 0.8 110.3 0.3 2.7 0.0 1.0 1.4 0.0 0.0 0.5 0.1 0.1 7.3 0.4 14.5 0.6 1.8 0.1 0.0 0.0 0.0 0.1 0.8 2.5 5.2 10.2 1.0 0.5 1.7 0.7 9.5 1.3 EBLN2 ENSG00000255423 "Endogenous Bornavirus like nucleoprotein 2" Q6P2I7 3 73061659-73063337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA062510, HPA068795" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" Nucleoplasm "HPA062510: AB_2684787, HPA068795: AB_2686038" "unprognostic (1.23e-2)" "unprognostic (3.34e-2)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.29e-3)" "unprognostic (7.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.81e-2)" "unprognostic (5.24e-3)" "unprognostic (2.89e-1)" "unprognostic (8.19e-3)" "unprognostic (8.38e-6)" "unprognostic (1.54e-1)" "unprognostic (1.47e-1)" "unprognostic (6.06e-2)" "unprognostic (1.12e-1)" 2.3 1.2 0.5 2.3 1.7 15.4 2.3 1.0 1.1 2.5 1.9 1.8 1.3 2.6 2.4 1.6 2.6 1.3 1.9 0.6 1.2 0.9 1.7 2.7 2.0 1.7 0.9 3.7 2.2 0.7 1.2 2.0 1.9 1.5 2.4 2.7 2.7 0.8 1.4 2.2 2.1 1.5 0.8 2.4 1.9 1.1 1.3 1.5 2.1 0.3 1.7 1.8 2.5 4.4 0.6 0.4 2.6 2.3 0.6 1.4 1.9 1.0 0.2 0.6 0.5 1.3 2.1 1.7 0.4 1.4 0.6 0.9 1.0 1.1 1.3 0.6 0.6 1.1 3.0 1.1 0.3 2.2 2.4 1.4 0.8 1.3 1.3 1.2 0.9 1.4 0.8 2.5 0.7 1.4 1.0 3.0 1.6 0.5 0.7 2.7 0.6 1.0 0.7 2.8 0.6 1.2 0.6 1.1 0.3 1.8 1.7 0.8 1.7 0.7 1.4 2.0 1.6 2.5 1.3 1.3 0.7 2.3 1.3 0.1 0.7 3.3 1.6 0.2 1.3 0.7 1.4 1.4 0.2 1.2 1.2 1.7 1.5 0.5 0.3 1.0 1.9 0.1 0.5 1.7 1.0 1.1 0.6 1.2 1.7 0.9 1.9 0.8 1.3 4.4 4.3 0.0 2.2 0.0 5.8 5.7 12.6 6.7 1.8 5.3 3.2 3.0 1.1 12.8 6.2 3.7 8.4 9.7 5.9 6.8 0.0 3.2 1.8 4.0 4.4 4.6 4.2 6.1 0.0 1.6 6.2 3.9 4.1 7.4 1.3 9.2 10.8 5.1 2.8 3.3 0.0 4.0 4.1 5.1 11.5 0.8 8.4 5.4 1.8 0.0 5.2 2.0 5.2 0.0 0.0 3.9 4.1 3.8 5.2 9.3 6.2 0.5 6.3 6.0 6.6 8.0 4.8 3.5 5.0 1.1 6.3 14.6 6.8 6.7 5.1 13.2 EDRF1 "C10orf137, DKFZp586F1019, FLJ21617" ENSG00000107938 "Erythroid differentiation regulatory factor 1" Q3B7T1 10 125719515-125764143 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031820 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA031820: AB_10600753" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.64e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-2)" "unprognostic (8.84e-4)" "unprognostic (4.76e-3)" "unprognostic (8.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.63e-3)" "unprognostic (4.62e-2)" "prognostic unfavorable (3.16e-5)" "unprognostic (3.44e-3)" "unprognostic (5.51e-2)" "unprognostic (1.38e-1)" "unprognostic (7.68e-3)" 4.1 4.0 2.0 6.1 2.7 21.8 5.6 5.3 2.9 5.6 2.7 4.0 5.0 7.4 4.9 4.7 4.6 4.1 5.1 2.9 2.0 3.6 2.8 4.2 9.7 1.7 1.7 8.0 7.2 4.3 2.9 5.7 2.3 6.8 5.2 4.6 12.3 4.1 5.7 5.1 4.5 5.2 1.5 5.4 4.7 15.1 1.7 9.4 5.2 5.1 8.2 4.4 3.3 4.1 12.6 11.7 15.4 16.5 7.2 10.0 7.8 14.8 13.6 16.3 18.5 15.7 10.4 16.5 6.9 9.6 9.5 15.3 22.6 4.7 18.0 10.3 18.3 12.0 12.5 8.9 9.6 17.0 12.1 6.5 6.0 16.2 8.1 15.6 7.8 8.9 11.1 11.2 10.6 5.3 16.9 11.8 20.6 7.7 10.2 14.0 13.2 9.7 6.5 7.2 7.6 14.9 10.7 5.9 10.1 13.9 10.3 6.8 5.4 8.8 9.6 12.4 17.1 15.0 11.4 26.1 9.3 8.8 5.0 5.9 2.3 1.4 2.7 2.0 3.4 3.1 2.2 2.5 3.0 2.3 2.2 2.8 2.9 2.9 1.3 2.9 3.1 1.4 2.0 2.7 5.3 2.9 2.9 2.0 1.7 1.7 2.3 1.5 1.7 4.1 12.4 12.8 9.7 26.1 19.1 5.9 5.7 5.1 15.4 23.9 9.3 8.4 12.9 8.6 9.0 11.0 33.3 6.7 28.5 5.1 0.0 4.3 145.1 11.2 14.6 9.5 4.2 7.6 40.9 7.2 6.0 12.1 17.3 27.2 20.3 24.7 7.5 7.0 4.1 20.2 31.7 7.5 4.1 7.7 4.2 61.5 21.1 9.2 7.2 22.5 12.2 9.1 13.4 22.1 36.2 8.3 4.9 19.9 27.1 6.6 7.1 2.7 8.6 24.4 6.6 13.0 11.0 26.8 21.4 10.6 8.2 4.5 20.1 18.5 7.3 5.2 EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" Cytosol "HPA054991: AB_2682664, HPA058735: AB_2683802" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (8.76e-2)" "unprognostic (1.36e-3)" "unprognostic (2.31e-1)" "unprognostic (1.59e-3)" "unprognostic (7.63e-3)" "unprognostic (1.40e-1)" "unprognostic (1.28e-3)" "unprognostic (3.96e-1)" 15.7 17.7 15.3 19.9 15.8 44.6 16.0 18.7 19.8 13.1 14.4 15.8 15.1 15.9 16.2 21.0 15.3 13.0 17.1 16.4 17.7 15.2 17.3 15.0 23.4 16.1 15.7 20.4 19.2 17.1 16.6 21.1 16.3 13.4 14.7 16.6 16.8 14.9 27.2 23.1 16.9 14.8 14.8 20.0 16.1 19.4 17.3 19.9 13.8 23.3 27.6 17.1 14.5 18.4 51.0 43.9 35.0 35.9 27.6 28.8 32.8 36.4 34.6 44.2 37.7 44.8 47.5 38.2 62.6 41.2 38.0 34.9 42.2 48.8 41.5 35.1 21.7 54.4 52.0 46.4 33.7 50.3 41.8 24.1 41.9 65.3 44.1 31.2 31.0 40.9 81.1 54.4 64.7 68.7 46.6 55.1 25.9 23.3 47.5 50.3 35.9 75.0 25.6 31.8 26.5 31.2 39.3 54.7 41.5 28.1 53.1 31.0 36.5 59.7 39.9 47.8 36.1 66.7 85.5 79.8 42.9 33.8 39.5 52.6 20.5 13.5 17.7 16.6 13.6 19.4 15.0 13.0 21.3 19.0 14.1 13.5 13.1 16.4 21.3 12.7 15.3 13.3 15.3 15.8 18.7 19.8 16.4 17.7 16.1 15.7 16.3 14.8 17.3 18.4 8.2 3.2 5.4 3.3 16.2 37.7 12.2 13.4 12.5 7.2 14.2 9.1 16.2 14.3 7.3 5.5 14.6 16.3 17.7 11.6 15.6 12.7 18.3 9.0 8.3 11.6 2.4 21.0 3.0 13.1 23.0 11.4 7.1 10.5 12.7 31.7 16.4 16.5 24.5 11.8 2.8 11.2 6.1 10.4 29.5 14.3 12.2 14.4 12.4 1.0 17.6 10.5 17.5 5.5 4.5 29.0 15.2 5.7 22.6 13.2 13.8 15.7 10.6 18.5 6.6 9.8 27.0 31.3 23.2 15.7 48.9 25.3 16.2 7.4 10.9 13.2 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm NA NA 280000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favorable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.68e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 65.8 81.4 19.0 49.1 21.1 185.8 44.2 21.5 27.2 51.2 22.8 44.3 38.6 46.6 38.8 81.9 54.7 40.1 38.0 22.3 21.0 45.1 42.6 44.0 67.0 19.9 19.5 66.5 37.0 58.5 41.1 52.9 20.3 38.7 47.5 32.3 42.4 32.6 37.3 64.8 38.9 42.6 22.7 47.6 41.4 42.8 20.0 78.2 37.0 34.9 74.7 83.4 55.1 24.7 237.2 208.9 140.5 103.8 105.5 63.2 114.4 119.3 91.0 177.7 141.4 223.7 110.3 221.4 67.9 112.9 126.4 152.2 194.9 136.2 195.0 71.5 192.3 142.5 159.3 244.3 103.1 253.8 133.4 98.7 68.7 149.5 119.4 71.8 147.2 128.7 189.8 140.2 105.3 178.9 224.8 132.8 145.0 223.8 190.0 168.5 282.7 172.2 85.8 196.5 186.1 100.1 170.9 334.2 151.9 130.1 219.3 166.7 100.5 108.7 138.6 159.9 200.3 104.4 86.2 403.2 88.0 158.7 113.3 126.1 167.0 137.4 101.1 174.6 131.2 142.4 128.2 119.4 200.0 119.8 116.9 115.2 98.7 132.9 143.4 326.0 158.2 232.6 19.0 21.1 21.5 27.2 22.3 21.0 19.9 19.5 20.3 22.7 20.0 24.7 117.9 41.7 48.0 6.8 135.1 283.1 273.4 212.9 107.0 23.3 77.0 109.2 61.5 38.6 107.8 29.5 16.7 140.1 165.7 75.4 64.6 85.6 33.2 132.9 109.2 70.5 60.3 24.4 4.1 115.2 225.1 144.3 149.4 248.2 92.6 42.6 32.2 27.0 108.5 6.7 4.3 83.2 89.5 63.4 255.0 12.1 67.1 199.6 103.2 10.3 67.9 48.6 23.7 5.5 7.6 86.6 83.1 49.7 118.6 96.0 47.9 65.0 61.4 32.5 85.5 109.7 207.8 99.4 123.2 77.6 299.1 261.9 138.4 98.0 77.7 252.5 ELF1 ENSG00000120690 "E74 like ETS transcription factor 1" P32519 13 40931924-41061440 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 200.9" "Cell type enhanced" "Detected in all" "T-cells: 365.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 271.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001755, CAB005172" Enhanced Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB005172: AB_631428, HPA001755: AB_1078732" "unprognostic (1.21e-1)" "unprognostic (8.73e-3)" "unprognostic (4.20e-2)" "unprognostic (8.45e-2)" "unprognostic (2.01e-1)" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.11e-2)" "unprognostic (5.78e-2)" "unprognostic (3.38e-2)" "unprognostic (2.17e-1)" "unprognostic (6.02e-3)" "unprognostic (2.96e-1)" "unprognostic (4.11e-2)" "unprognostic (8.98e-2)" "unprognostic (3.72e-2)" 64.2 22.5 8.8 64.3 14.5 200.9 45.3 13.8 9.9 45.8 11.1 45.6 53.4 35.3 28.9 52.6 41.1 59.6 29.1 8.9 12.4 31.9 50.4 47.3 95.3 19.7 14.1 34.6 56.1 39.8 9.7 48.6 19.5 35.2 48.3 4.2 35.3 33.9 21.3 38.5 57.8 43.9 13.7 68.3 49.7 15.1 14.9 134.5 54.9 25.9 96.9 61.3 36.5 21.0 35.5 20.5 15.3 15.3 68.6 72.6 57.2 35.9 84.9 48.7 55.1 51.2 90.9 199.7 22.1 60.4 36.5 78.7 2.9 45.4 30.8 44.9 23.7 179.6 16.3 36.5 50.9 103.3 271.2 75.1 78.5 32.9 62.0 32.8 69.2 93.1 45.0 51.7 32.4 32.5 136.6 63.1 12.1 117.7 15.8 179.2 25.1 58.7 49.9 54.8 6.1 21.3 31.0 31.0 62.9 21.2 22.0 132.8 63.8 21.5 12.4 17.7 13.0 23.7 14.8 131.2 29.0 65.0 45.9 265.9 60.4 134.2 70.0 66.1 73.8 63.0 79.3 77.9 58.6 65.1 84.8 75.9 97.4 73.0 98.4 38.9 86.8 80.1 8.8 14.5 13.8 9.9 8.9 12.4 19.7 14.1 19.5 13.7 14.9 21.0 156.8 76.9 68.0 51.6 326.8 108.8 188.2 86.0 90.0 2.8 71.5 37.7 41.3 52.9 86.1 57.0 10.4 35.7 292.0 62.9 19.6 70.2 47.7 121.6 69.5 122.0 58.1 78.8 8.2 69.4 55.8 79.0 64.2 126.0 323.1 8.1 91.4 25.2 97.5 3.3 8.6 57.0 95.6 115.4 206.3 21.9 42.9 244.1 120.9 125.5 123.5 8.1 133.9 52.8 138.7 65.9 54.4 43.2 211.5 150.4 58.7 28.3 84.6 3.7 39.5 52.7 52.8 7.7 11.2 95.6 114.8 53.5 365.3 26.9 56.0 221.9 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 15.7 13.7 6.8 17.7 8.9 65.1 14.2 20.5 10.8 16.0 6.1 16.6 13.6 17.2 13.5 16.3 16.4 14.2 11.5 7.1 9.4 13.1 15.5 14.7 17.6 10.6 7.8 23.9 18.0 23.2 13.4 19.3 7.7 15.0 14.5 17.8 15.0 15.6 20.4 18.9 16.0 16.4 5.3 17.0 14.5 19.6 8.6 27.2 20.2 23.4 17.9 15.4 14.8 11.2 31.6 21.7 35.4 23.0 22.2 23.3 32.3 15.0 21.8 21.0 21.0 27.8 12.0 32.7 12.2 28.4 18.7 24.1 48.1 20.8 23.5 30.5 32.2 24.4 25.4 22.3 26.9 59.3 26.5 24.8 22.2 30.0 27.0 19.3 24.9 18.7 26.3 43.9 18.3 12.5 16.2 18.9 27.5 38.3 15.2 33.7 16.7 21.3 20.3 40.4 11.3 11.9 51.1 26.0 25.6 29.5 17.8 33.9 31.3 20.3 24.8 16.3 20.8 28.5 14.1 47.9 16.3 17.4 21.5 3.6 1.7 1.6 1.6 1.9 1.5 2.2 1.7 1.7 2.1 1.4 1.4 1.1 4.9 2.7 1.0 1.6 1.4 1.2 6.8 8.9 20.5 10.8 7.1 9.4 10.6 7.8 7.7 5.3 8.6 11.2 45.4 67.3 49.2 58.1 53.8 24.6 22.9 11.6 40.9 44.6 35.1 25.8 31.6 38.6 15.8 25.8 35.5 18.4 63.2 37.0 3.9 16.1 15.3 55.1 56.4 36.2 24.7 60.4 71.8 18.7 17.9 32.0 27.5 72.5 25.3 36.1 32.9 29.2 18.4 25.2 73.6 24.2 2.0 60.7 25.7 6.4 28.9 60.5 8.8 45.9 52.0 27.7 40.2 81.4 80.3 25.8 28.9 30.5 51.2 30.8 20.2 10.8 22.8 30.9 26.3 47.6 36.7 22.8 31.2 35.3 25.9 30.2 46.0 36.7 23.7 36.3 EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules autophagy protein 5 homolog" Q9HCE0 18 45847609-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 53.1;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "LHCN-M2: 55.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA031689: AB_10609997" "unprognostic (3.43e-1)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.66e-1)" "unprognostic (4.87e-1)" "unprognostic (1.15e-2)" "unprognostic (7.50e-2)" "prognostic favorable (4.04e-5)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (1.18e-1)" 6.6 6.8 5.8 4.4 6.0 13.8 6.8 6.3 6.2 7.1 5.1 5.8 3.2 6.1 5.8 7.1 6.0 3.2 8.4 6.2 5.3 6.6 6.0 8.8 5.7 5.1 8.1 8.9 6.3 6.9 7.6 4.5 5.3 5.9 4.0 8.6 6.0 3.7 8.6 10.1 6.0 4.1 4.5 9.5 5.6 4.8 5.8 8.4 9.3 6.7 5.9 5.4 6.6 6.3 5.3 4.1 4.1 3.0 13.8 16.6 4.1 33.2 13.7 18.7 19.4 1.2 3.9 5.4 2.0 25.0 22.5 4.9 5.5 6.6 23.7 4.5 2.3 4.2 4.7 4.2 13.1 7.2 10.4 11.2 6.0 20.6 14.0 16.5 9.4 4.7 3.7 2.8 55.8 3.7 3.2 6.9 2.0 1.9 2.5 3.0 5.1 3.8 8.8 7.3 4.4 3.4 5.9 2.4 7.0 5.8 3.4 5.1 23.0 23.2 4.9 3.4 9.2 5.7 4.3 3.0 9.9 6.2 7.7 0.4 0.7 0.7 1.5 0.7 1.4 0.4 0.9 0.8 0.5 0.6 0.7 0.9 0.8 0.4 0.6 0.6 0.5 0.3 5.8 6.0 6.3 6.2 6.2 5.3 5.1 8.1 5.3 4.5 5.8 6.3 8.8 19.2 10.5 24.5 9.0 10.3 4.6 6.8 8.0 16.7 11.9 8.3 17.1 10.0 7.4 11.0 25.0 7.6 15.7 5.8 1.9 6.5 4.6 9.0 9.8 9.3 8.3 11.4 53.1 3.6 4.4 7.8 6.1 16.9 7.0 14.4 13.6 10.3 12.2 13.5 46.5 6.9 6.1 16.0 6.2 3.0 12.5 11.5 14.2 40.3 16.6 6.5 27.8 40.2 51.4 7.8 6.5 11.7 10.0 9.1 6.2 8.3 10.5 17.4 13.1 9.8 6.7 8.4 7.1 5.9 13.2 9.0 15.4 9.8 6.5 9.4 ETF1 "ERF, ERF1, RF1, SUP45L1, TB3-1" ENSG00000120705 "Eukaryotic translation termination factor 1" P62495 5 138506095-138543236 "Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 456.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011686, HPA037511" Approved NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" "CAB011686: AB_732263, HPA037511: AB_2675516" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "prognostic favorable (9.33e-5)" "unprognostic (1.63e-1)" "unprognostic (3.45e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (6.35e-4)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (2.44e-1)" "unprognostic (9.19e-2)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (2.10e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.63e-2)" 68.3 46.5 26.9 47.1 27.3 169.5 51.9 26.7 31.3 37.4 34.0 46.2 33.7 41.7 36.7 88.2 33.9 49.1 48.3 29.4 30.0 46.2 58.9 56.8 40.3 28.6 29.2 29.4 48.4 54.6 33.0 59.8 28.4 39.1 45.6 27.3 37.7 46.3 98.1 61.1 33.6 51.6 28.8 31.1 41.6 59.1 29.7 35.5 49.1 74.2 57.8 70.1 39.5 29.3 137.9 132.2 92.0 151.4 120.5 112.5 161.4 148.1 152.2 172.4 199.7 321.5 123.3 171.6 125.1 151.2 243.6 112.4 218.0 277.2 258.0 96.7 117.2 137.2 142.9 128.8 162.0 117.3 110.5 117.8 158.5 176.4 231.2 90.4 141.4 110.4 180.1 101.9 179.0 102.9 146.3 104.4 113.5 104.8 75.8 123.5 152.2 139.7 119.0 191.7 119.6 120.6 164.8 110.8 264.0 238.4 129.6 138.3 117.4 136.1 78.2 108.9 218.4 211.9 215.0 249.2 122.2 173.4 131.1 17.7 22.9 14.4 17.0 27.1 19.7 17.2 17.5 19.7 23.8 10.8 12.3 16.3 15.1 16.7 25.6 16.9 19.9 17.1 26.9 27.3 26.7 31.3 29.4 30.0 28.6 29.2 28.4 28.8 29.7 29.3 54.8 160.3 62.4 14.4 57.2 209.3 179.0 70.4 85.4 16.1 78.9 63.6 63.3 41.5 77.9 57.0 14.6 118.0 80.0 51.0 62.6 77.9 456.1 110.3 74.9 54.1 39.9 63.7 18.6 75.0 90.1 68.5 44.4 128.4 54.5 32.1 26.0 50.8 76.5 25.2 18.1 47.4 26.4 62.5 146.6 178.4 23.3 116.1 72.9 13.1 71.4 25.6 34.0 10.1 17.8 91.3 39.6 27.1 64.2 109.2 36.9 54.5 72.1 19.9 59.2 118.4 79.8 46.3 52.7 98.1 202.0 285.5 67.6 40.5 58.9 181.5 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.3;lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 7.4;Extravillous trophoblasts: 16.7;Plasma cells: 11.8;Spermatocytes: 9.3;Spermatogonia: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA053079: AB_2682037, HPA069738: AB_2732140" "unprognostic (6.33e-3)" "unprognostic (8.54e-3)" "unprognostic (9.47e-3)" "prognostic unfavorable (8.21e-4)" "unprognostic (2.43e-1)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.94e-7)" "unprognostic (1.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.40e-2)" "unprognostic (4.81e-3)" "unprognostic (9.40e-2)" "unprognostic (0.00e+0)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (3.57e-1)" 0.5 0.3 0.2 3.3 0.2 17.3 1.2 0.1 0.7 0.5 0.1 3.2 2.9 0.8 0.0 2.5 0.3 0.4 0.2 0.3 0.1 0.3 0.5 0.6 5.8 0.1 0.2 0.2 0.3 0.7 0.1 3.3 0.2 0.2 3.7 0.0 0.5 0.2 0.1 1.8 2.5 1.2 0.2 1.5 1.6 5.7 0.3 11.1 0.4 0.0 6.4 1.2 0.8 0.4 41.3 26.8 43.4 28.6 2.7 6.7 36.5 53.4 17.7 46.7 50.5 33.9 22.5 44.3 25.3 12.6 25.1 40.0 55.5 22.5 54.8 69.5 48.4 41.5 28.8 17.3 1.0 59.8 29.4 1.7 1.1 46.8 12.5 5.7 14.7 43.4 84.6 57.0 37.8 19.0 65.9 33.6 60.4 49.7 26.0 46.2 40.5 47.5 9.6 25.6 48.1 60.9 34.8 27.9 19.5 20.2 25.8 36.6 5.5 44.9 39.5 42.7 72.9 41.5 59.0 71.3 15.6 48.1 54.9 0.8 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.2 0.2 0.1 0.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.3 0.7 0.8 0.1 0.7 0.0 0.0 0.3 0.5 2.3 0.0 0.1 0.0 0.0 5.3 0.2 1.2 0.0 0.1 9.3 0.3 0.4 0.7 0.0 7.4 1.0 0.0 16.7 0.9 1.1 0.5 0.0 4.6 0.4 0.0 3.3 0.0 2.9 0.5 0.0 0.3 0.8 2.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 11.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 9.3 9.8 2.7 0.1 4.0 0.8 0.8 1.9 0.3 FAM117A ENSG00000121104 "Family with sequence similarity 117 member A" Q9C073 17 49710332-49789180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "dendritic cells: 56.4;Erythroid cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 50.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 82.0;U-266/84: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022531 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA022531: AB_2101087" "prognostic favorable (5.30e-5)" "unprognostic (8.06e-3)" "unprognostic (2.82e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-1)" "unprognostic (3.90e-3)" "unprognostic (1.69e-1)" "prognostic favorable (8.25e-7)" "unprognostic (4.05e-1)" "unprognostic (3.58e-1)" "prognostic favorable (1.81e-4)" "unprognostic (1.99e-2)" "unprognostic (3.73e-2)" "unprognostic (9.12e-2)" "unprognostic (1.45e-1)" "unprognostic (4.07e-2)" "unprognostic (4.66e-2)" 13.5 7.3 7.6 14.8 6.8 76.5 12.5 10.0 5.9 12.6 37.4 22.8 10.6 20.4 9.6 9.4 16.7 10.4 18.9 9.6 4.8 9.0 11.7 12.1 22.9 6.3 4.6 21.6 16.0 18.6 14.6 5.4 6.1 10.0 8.5 8.0 13.5 11.3 4.0 19.1 18.7 16.7 3.3 34.2 13.3 19.0 6.7 23.5 14.5 6.3 17.4 20.2 10.5 5.0 7.2 1.7 11.4 0.2 5.0 1.0 20.2 2.4 4.0 4.3 7.1 51.2 11.8 34.4 12.4 1.4 19.1 4.1 9.0 8.5 3.3 2.4 14.5 37.9 0.1 16.6 5.6 5.8 29.1 4.9 7.1 7.1 3.9 4.4 7.8 28.9 46.9 28.1 4.1 18.6 37.5 31.1 17.0 10.0 5.7 11.6 9.6 18.4 6.7 6.4 11.1 7.5 2.4 1.1 8.5 11.1 16.7 21.5 0.7 4.2 3.4 4.6 2.0 82.0 60.2 23.0 3.6 8.4 3.5 50.4 1.7 9.1 8.5 1.1 9.2 23.6 5.5 7.2 1.3 15.3 4.5 6.2 3.6 12.8 0.3 3.6 5.9 3.4 7.6 6.8 10.0 5.9 9.6 4.8 6.3 4.6 6.1 3.3 6.7 5.0 15.5 6.4 9.3 5.2 19.5 9.1 1.3 2.1 7.4 15.1 14.6 21.7 22.2 1.5 4.1 7.3 14.6 1.1 56.4 2.2 5.9 2.0 4.1 4.2 5.9 9.9 10.7 104.4 4.5 3.5 1.9 9.3 9.2 7.9 2.5 2.9 7.1 8.6 1.2 5.0 4.0 4.9 6.1 2.9 4.5 5.6 14.3 7.6 7.2 1.9 13.0 3.5 37.0 2.0 2.3 3.8 1.0 15.4 34.9 2.6 0.5 3.6 1.5 4.0 0.0 14.2 10.2 15.5 14.5 8.8 14.1 0.8 27.9 5.5 2.7 1.1 FAM76B MGC33371 ENSG00000077458 "Family with sequence similarity 76 member B" Q5HYJ3 11 95768953-95790409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.5" "Group enriched" "Detected in many" 7 "Early spermatids: 261.6;Late spermatids: 372.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036608 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli fibrillar center" "HPA036608: AB_2675215" "unprognostic (8.17e-2)" "unprognostic (2.26e-1)" "unprognostic (8.21e-2)" "unprognostic (2.39e-2)" "unprognostic (3.12e-2)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (2.64e-2)" "unprognostic (1.01e-2)" "unprognostic (1.65e-2)" "unprognostic (1.22e-1)" "unprognostic (3.90e-3)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (2.43e-1)" "prognostic favorable (2.72e-4)" 5.8 5.0 1.1 12.5 1.6 39.5 5.2 4.2 2.3 4.2 1.7 4.9 9.2 6.8 1.6 4.0 3.9 5.3 4.0 1.2 1.0 3.1 8.2 5.0 17.1 1.9 1.8 5.5 6.1 3.7 2.3 6.7 1.8 4.7 5.1 5.3 4.7 3.3 3.9 5.8 6.4 4.5 1.1 8.4 5.9 17.7 1.8 14.2 5.5 3.7 17.6 4.9 3.7 3.4 8.0 6.0 22.1 12.0 3.6 3.6 18.4 13.4 6.4 9.6 11.0 22.4 15.3 29.8 16.5 6.4 12.5 15.0 13.1 4.5 10.1 16.1 9.5 35.0 10.9 11.8 9.2 25.0 19.3 4.7 7.3 11.1 9.9 6.3 9.3 17.5 21.1 16.1 5.5 5.8 28.0 29.9 12.3 8.5 5.4 30.0 16.5 17.7 7.3 8.8 9.3 26.3 16.3 9.1 10.1 7.4 12.1 10.9 9.5 13.4 14.1 15.8 12.3 8.8 19.7 45.5 3.2 23.8 19.2 0.1 1.9 3.5 3.3 2.0 2.7 1.8 3.0 3.4 1.3 1.5 2.7 4.1 5.7 3.3 1.9 4.8 5.2 1.8 1.1 1.6 4.2 2.3 1.2 1.0 1.9 1.8 1.8 1.1 1.8 3.4 27.9 6.4 16.5 14.7 41.5 13.8 12.5 8.4 22.8 16.1 17.0 16.4 12.9 8.6 14.0 5.5 27.1 8.5 28.9 10.5 0.0 7.7 261.6 23.2 23.4 19.2 20.4 34.1 18.7 7.5 10.1 14.9 15.3 18.3 10.8 21.0 15.4 19.8 8.3 11.8 15.9 14.0 4.1 18.0 18.0 372.1 17.1 20.0 16.0 13.1 17.7 12.4 19.6 16.6 30.1 9.1 16.0 15.4 16.2 12.5 10.3 2.4 12.3 15.1 26.3 17.6 21.3 31.8 20.9 14.4 16.1 7.7 26.4 15.0 10.8 10.7 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.1;lymphoid tissue: 27.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.0;Extravillous trophoblasts: 30.5;Spermatocytes: 32.3;Spermatogonia: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008106: AB_828450, HPA029048: AB_10602132" "unprognostic (1.22e-2)" "unprognostic (7.21e-2)" "unprognostic (4.61e-3)" "unprognostic (1.24e-2)" "unprognostic (5.92e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-8)" "unprognostic (2.46e-2)" "unprognostic (1.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.25e-9)" "prognostic favorable (8.65e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" 3.1 3.1 1.5 7.3 1.6 44.1 4.5 2.6 2.1 4.0 1.9 5.0 4.6 5.3 4.5 3.7 3.0 2.6 1.8 1.4 1.7 3.1 4.4 3.4 14.9 1.6 1.6 4.1 3.0 2.3 2.1 6.3 1.7 3.0 5.1 3.3 2.7 2.9 0.9 4.3 4.3 5.0 1.6 5.5 4.6 3.9 1.8 27.3 4.4 2.6 14.6 4.0 3.0 2.0 33.7 17.2 70.8 48.1 5.3 10.8 22.6 79.9 35.5 58.7 65.6 35.6 19.8 81.6 23.9 21.3 39.7 31.4 56.4 26.7 70.0 44.2 50.6 82.3 24.1 38.7 10.2 74.4 48.6 7.7 4.9 39.8 30.9 14.3 27.3 42.3 88.2 74.5 53.9 25.7 85.2 47.6 41.5 25.8 25.0 71.0 56.8 52.8 20.8 18.0 46.1 47.9 56.6 30.2 15.6 24.7 21.8 68.7 20.6 43.9 57.4 51.1 94.8 24.9 29.5 120.4 31.9 54.3 54.2 0.0 1.9 0.0 2.8 2.5 4.0 5.1 4.7 5.2 3.7 5.0 4.6 4.8 0.0 7.1 3.2 4.3 6.6 2.5 1.5 1.6 2.6 2.1 1.4 1.7 1.6 1.6 1.7 1.6 1.8 2.0 6.0 0.0 1.1 1.3 9.8 9.9 3.7 4.0 7.4 3.2 5.7 5.2 1.8 2.8 3.9 1.8 6.2 15.2 13.5 2.6 3.9 3.0 0.4 2.3 10.5 5.7 4.8 36.0 1.0 1.6 30.5 9.1 7.7 4.0 2.5 16.6 5.0 1.9 7.9 1.7 0.9 6.1 2.0 3.2 6.1 0.1 4.4 5.3 1.8 1.9 4.2 4.1 9.2 1.5 2.1 1.5 0.5 6.0 24.7 3.6 1.5 3.6 1.9 3.6 13.1 8.6 8.9 32.3 26.1 10.2 5.3 5.9 7.9 8.0 6.3 2.0 FBXW2 "FBW2, Fwd2, Md6" ENSG00000119402 "F-box and WD repeat domain containing 2" Q9UKT8 9 120751978-120793416 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 177.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067878 Approved Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA067878: AB_2685913" "unprognostic (1.08e-1)" "unprognostic (1.45e-1)" "unprognostic (5.06e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" "unprognostic (6.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.57e-1)" "unprognostic (8.06e-3)" "unprognostic (1.40e-1)" "unprognostic (2.95e-1)" "unprognostic (3.88e-3)" "prognostic favorable (1.38e-6)" "unprognostic (1.66e-1)" "unprognostic (2.75e-1)" "unprognostic (2.86e-1)" "unprognostic (3.83e-2)" 23.7 21.7 10.0 21.0 10.3 37.4 20.1 10.5 10.6 21.7 11.7 18.0 16.7 19.9 15.4 21.3 16.5 14.7 23.5 11.8 10.9 18.0 22.2 23.1 22.1 9.5 10.5 16.9 18.5 22.7 13.0 17.4 9.4 18.4 19.8 15.2 19.0 18.8 16.1 21.4 16.0 22.7 9.5 22.5 18.7 17.7 12.2 26.3 19.9 21.7 25.3 22.4 16.7 11.4 30.1 37.3 27.5 46.5 50.7 41.4 25.4 39.5 45.1 42.7 41.3 29.8 35.4 44.9 20.4 51.8 43.1 64.4 39.9 39.4 53.0 60.6 17.2 29.1 64.8 43.5 28.6 65.6 38.6 30.3 47.9 47.2 50.0 40.1 50.8 45.7 39.4 47.5 37.4 48.2 47.3 19.6 41.0 50.8 35.3 36.1 43.8 45.1 29.5 33.5 21.9 33.0 55.3 40.6 29.5 32.2 66.5 18.7 38.1 36.3 28.9 59.3 49.6 34.1 74.2 38.5 38.4 28.7 38.1 15.3 12.0 17.2 17.3 11.4 13.1 10.0 12.3 16.3 11.0 6.2 10.0 13.8 12.4 15.5 13.7 9.6 13.0 9.8 10.0 10.3 10.5 10.6 11.8 10.9 9.5 10.5 9.4 9.5 12.2 11.4 32.3 25.6 56.9 17.3 17.6 22.7 26.4 27.3 13.1 20.0 23.5 16.6 21.9 12.8 28.7 11.0 12.5 18.5 50.9 27.1 21.5 27.1 38.8 14.5 22.7 31.9 27.6 24.0 34.0 34.0 29.2 23.2 28.1 17.8 15.8 27.2 33.5 33.9 25.2 33.7 29.0 19.0 28.5 25.0 30.0 177.2 26.4 21.7 48.0 23.4 38.0 16.5 36.0 27.6 37.0 32.5 19.4 35.7 24.5 34.9 22.7 24.7 21.0 25.1 6.6 20.4 36.1 40.5 53.7 21.9 32.0 17.8 31.2 31.0 23.2 28.1 FEM1C "EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785" ENSG00000145780 "Fem-1 homolog C" Q96JP0 5 115520908-115544775 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059919, HPA060977" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA059919: AB_2684161, HPA060977: AB_2684402" "unprognostic (1.14e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.83e-4)" "unprognostic (1.28e-1)" "unprognostic (3.31e-1)" "unprognostic (7.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (4.67e-2)" "unprognostic (5.52e-3)" "unprognostic (1.99e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (1.37e-2)" "unprognostic (1.05e-2)" 13.6 5.6 6.1 7.9 9.5 63.2 10.6 13.4 10.7 12.5 1.1 13.3 11.1 9.8 6.1 14.7 6.1 12.3 15.7 5.3 4.4 7.4 15.7 11.1 6.9 6.3 7.2 7.6 11.0 5.5 4.2 6.2 5.4 9.7 12.2 17.1 5.8 6.9 20.6 10.1 12.1 10.3 4.8 8.5 10.6 13.6 9.5 6.6 8.2 21.3 6.6 9.8 7.7 7.9 11.8 7.0 9.8 15.3 17.3 24.1 7.9 18.3 14.5 13.5 15.6 7.7 10.2 12.0 12.2 13.5 15.5 9.0 8.0 15.2 19.7 18.6 7.6 6.3 9.7 5.9 11.5 4.2 8.2 15.9 12.6 16.8 15.1 12.5 13.4 9.8 4.0 15.3 20.5 5.1 11.0 7.1 6.9 7.5 8.7 9.3 17.9 13.1 14.9 22.1 8.0 6.5 11.8 8.1 20.1 7.8 10.5 8.4 23.7 23.0 12.0 21.3 16.4 12.0 9.4 9.4 13.4 11.6 9.5 2.5 4.7 5.0 2.7 6.9 3.9 2.3 2.8 2.0 4.6 1.3 3.1 2.6 4.8 2.2 8.8 1.2 3.4 2.8 6.1 9.5 13.4 10.7 5.3 4.4 6.3 7.2 5.4 4.8 9.5 7.9 35.4 22.4 13.6 28.4 15.3 26.5 15.8 7.8 18.8 17.2 17.6 13.0 31.5 20.0 14.8 11.0 20.9 4.4 15.8 64.7 5.9 11.6 48.1 31.1 33.0 18.8 16.7 12.2 13.3 8.4 8.6 27.5 23.0 36.9 13.3 29.6 17.9 47.0 7.6 5.0 7.2 27.5 8.2 15.8 52.9 80.7 8.7 22.5 30.2 5.6 9.7 23.1 5.2 15.1 18.2 17.1 53.2 6.8 19.4 18.9 31.7 12.3 18.3 28.2 0.0 24.0 22.8 16.5 6.3 25.4 24.7 5.1 16.7 8.0 21.5 40.2 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 504.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 504.8" "Cell line enhanced" "Detected in many" "hTCEpi: 453.1;OE19: 170.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 80.9;spinal cord: 235.3" HPA018531 Approved Supported Nucleoplasm Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018531: AB_1846576" "unprognostic (1.18e-2)" "unprognostic (8.70e-2)" "unprognostic (1.61e-1)" "unprognostic (3.80e-1)" "unprognostic (3.08e-2)" "unprognostic (4.82e-2)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (9.55e-3)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.81e-4)" "unprognostic (3.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.66e-2)" 1136.1 735.7 62.9 576.0 87.2 2270.6 477.4 184.8 113.1 700.5 111.5 479.5 235.3 410.4 58.4 1250.8 1777.3 1160.0 513.1 58.9 190.7 266.1 308.8 486.9 449.9 145.1 84.0 1188.7 298.4 264.7 452.3 417.4 92.0 791.1 627.4 233.3 555.6 462.3 99.1 1645.4 584.5 964.3 100.6 178.0 525.6 87.2 104.4 424.2 1007.6 1014.2 26.8 946.5 346.6 121.7 2.2 1.4 7.1 10.4 59.9 18.3 42.1 6.4 2.4 4.5 3.2 4.4 12.6 0.6 1.8 43.5 42.6 3.0 3.6 74.7 1.1 1.2 1.1 1.0 21.9 1.9 27.6 2.6 42.8 44.3 453.1 3.9 27.4 6.2 2.7 9.2 2.0 19.7 1.2 26.1 0.9 12.9 7.4 170.9 2.5 2.0 1.4 23.8 18.8 20.4 52.4 3.6 9.8 85.9 39.8 21.8 1.4 9.2 6.3 0.4 5.7 3.7 2.0 52.4 61.2 9.6 2.9 8.0 5.7 38.3 81.0 89.5 0.3 20.1 0.4 0.3 0.2 0.7 69.6 0.2 0.2 0.1 504.8 4.6 2.5 1.5 0.4 27.7 62.9 87.2 184.8 113.1 58.9 190.7 145.1 84.0 92.0 100.6 104.4 121.7 3911.0 1102.6 1859.4 137.1 1015.9 859.7 1644.7 1577.5 4336.7 106.1 3184.1 2874.6 1027.6 1416.9 752.7 191.3 129.3 1506.7 1323.5 1648.6 17.6 690.9 17.4 1834.4 3720.3 1624.0 1628.0 290.5 4.9 528.1 2694.6 4146.8 2049.5 3656.5 1630.6 751.3 1317.2 207.2 1693.8 35.3 3.0 1967.2 793.5 2600.2 1540.4 53.5 943.8 2910.7 855.6 58.1 269.5 1119.5 10.3 6.0 1.8 383.5 1507.8 178.3 1256.1 1115.7 1675.1 20.0 354.4 406.9 1209.6 3390.9 2705.7 10.0 10.5 2438.0 1092.4 2283.3 1497.0 417.4 1366.2 298.4 FOSL2 "FLJ23306, FRA2" ENSG00000075426 "FOS like 2, AP-1 transcription factor subunit" P15408 2 28392448-28417317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 287.6;Langerhans cells: 319.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 36.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004817, CAB013460, HPA061417" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB013460: , HPA004817: AB_1849014, HPA061417: AB_2684509" "unprognostic (1.21e-1)" "unprognostic (3.60e-1)" "unprognostic (1.21e-1)" "unprognostic (8.55e-2)" "unprognostic (1.28e-3)" "unprognostic (3.41e-2)" "unprognostic (7.24e-2)" "unprognostic (3.78e-3)" "unprognostic (1.08e-1)" "unprognostic (7.73e-3)" "unprognostic (1.40e-2)" "unprognostic (2.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (1.72e-2)" "unprognostic (1.99e-2)" "unprognostic (2.79e-2)" 149.4 169.7 18.8 67.6 18.4 232.1 78.6 18.8 31.8 83.0 17.4 64.3 30.2 77.8 7.0 129.5 85.7 79.6 75.1 34.7 32.2 65.8 30.9 83.4 9.1 36.0 19.3 133.5 37.2 7.5 46.6 46.9 18.8 53.8 40.2 10.7 47.4 26.7 101.7 103.4 52.2 81.5 18.2 32.7 76.6 7.3 23.5 17.2 35.2 33.9 16.6 82.3 112.1 15.0 45.0 30.2 2.0 23.2 23.9 41.6 62.0 37.7 38.0 58.8 51.1 35.9 34.6 0.2 53.9 48.6 59.6 42.0 2.5 49.7 52.6 10.6 3.1 4.6 59.3 6.3 37.3 7.9 18.9 66.9 123.3 69.0 60.5 49.5 31.2 1.5 0.6 12.5 39.7 7.3 0.7 24.3 3.6 45.2 14.8 1.8 57.4 4.3 94.3 152.5 15.7 2.3 61.0 35.2 10.9 16.8 3.8 35.5 93.8 122.8 81.9 72.3 55.2 19.1 7.6 0.2 81.5 43.3 21.6 17.2 9.9 8.7 7.7 7.3 7.4 0.0 1.6 3.8 3.9 0.0 0.4 2.5 36.6 4.6 6.4 1.3 1.2 5.1 18.8 18.4 18.8 31.8 34.7 32.2 36.0 19.3 18.8 18.2 23.5 15.0 183.1 32.1 50.9 4.6 20.2 143.1 86.3 85.8 90.0 0.8 76.4 41.7 27.9 70.1 59.7 167.3 0.0 27.4 287.6 140.6 19.6 58.5 1.3 115.7 88.0 111.0 28.1 4.4 11.9 59.8 148.3 79.7 115.7 193.6 108.3 68.1 56.7 16.5 37.4 0.0 8.1 65.2 40.7 58.0 319.8 4.3 22.4 181.2 85.4 15.0 62.8 2.3 53.5 0.5 0.6 54.1 91.5 24.5 67.0 82.2 124.8 35.1 38.2 1.4 26.3 93.8 122.3 1.6 2.5 157.6 150.7 50.2 142.4 23.6 57.6 152.8 FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 70.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA049763: AB_2680868" "unprognostic (4.93e-2)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (4.04e-3)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.17e-3)" "unprognostic (2.60e-1)" "unprognostic (8.02e-2)" "unprognostic (4.60e-2)" "unprognostic (3.25e-2)" "prognostic favorable (2.55e-4)" "unprognostic (7.87e-3)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.08e-2)" 5.3 3.6 7.2 10.4 7.1 31.0 8.0 7.7 7.4 6.0 9.8 17.1 25.1 4.1 6.2 14.4 7.1 4.0 6.0 6.3 6.8 7.8 18.3 9.7 8.7 7.7 7.6 2.8 14.0 5.2 3.0 7.4 6.8 7.9 15.5 3.3 15.1 4.3 10.1 20.4 15.9 4.1 7.0 28.9 13.2 14.6 7.5 8.9 5.3 9.1 10.8 6.7 8.1 6.0 10.9 4.3 6.9 31.2 4.9 4.0 25.7 2.4 8.9 3.7 3.7 6.8 12.5 13.3 8.4 2.5 2.2 20.3 18.3 9.5 2.9 20.0 28.0 17.9 9.2 15.0 2.8 28.9 20.6 3.2 20.0 3.6 11.4 7.9 9.3 11.7 15.8 4.2 1.8 17.9 12.6 36.5 42.9 36.2 17.5 12.8 2.9 19.1 8.9 9.8 12.5 10.2 3.1 19.1 12.6 28.0 28.8 44.8 4.2 2.2 2.7 1.7 6.4 11.4 12.5 6.6 2.6 49.3 0.8 8.3 7.2 15.0 1.1 4.8 0.6 1.1 1.3 1.8 3.8 3.2 2.2 1.3 58.2 1.6 7.9 1.0 0.7 2.3 7.2 7.1 7.7 7.4 6.3 6.8 7.7 7.6 6.8 7.0 7.5 6.0 18.2 0.0 3.9 2.9 15.7 31.7 25.3 6.6 46.1 19.7 24.7 19.6 6.4 20.0 5.0 14.7 4.2 6.1 26.1 31.0 11.7 2.2 40.7 39.6 9.7 10.3 13.8 14.5 2.0 5.3 18.5 6.4 37.2 46.3 1.3 16.7 8.6 11.3 8.6 11.8 2.8 30.6 4.1 28.3 9.0 42.3 2.1 25.2 10.6 7.5 24.7 5.0 14.4 2.0 1.1 3.4 21.6 2.6 8.4 30.0 13.5 3.7 4.5 18.1 0.0 14.9 8.7 2.3 4.4 37.7 52.7 7.8 18.8 20.1 31.6 32.3 G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154531391-154547572 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.9" "Cell type enhanced" "Detected in many" "monocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 412.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 412.7" "Cell line enhanced" "Detected in all" "A549: 2333.8;MCF7: 883.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Enhanced "Centriolar satellite,Cytosol" No No 2400000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Centriolar satellite" "HPA000247: AB_1078978, HPA000834: AB_1078977" "unprognostic (1.73e-2)" "unprognostic (1.53e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (7.78e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (9.45e-13)" "unprognostic (2.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (2.89e-3)" "unprognostic (2.83e-1)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.25e-2)" 40.7 39.1 19.9 30.2 21.8 105.9 31.9 20.5 28.3 20.6 20.0 13.9 13.1 21.6 13.3 54.3 19.3 46.5 14.3 21.3 22.7 12.7 6.5 29.4 28.9 25.4 22.2 24.1 13.0 9.6 27.5 13.7 24.5 12.2 13.1 26.1 21.2 14.4 4.2 21.3 12.4 25.6 19.7 26.9 18.1 54.0 26.1 26.2 45.9 5.1 37.2 33.8 22.4 21.9 168.5 2333.8 49.7 189.7 207.2 281.7 43.5 116.0 341.7 120.0 205.8 111.2 61.9 110.9 174.1 274.3 475.9 146.3 79.3 202.5 60.3 111.4 55.0 116.8 517.2 244.6 401.6 117.8 373.5 136.6 58.5 233.9 49.8 185.6 252.5 79.8 69.6 46.3 218.4 883.9 77.5 93.0 35.3 549.5 172.2 74.9 28.4 120.5 357.1 210.9 49.6 62.0 115.9 444.5 99.9 65.0 67.1 99.4 289.8 73.1 250.0 102.5 181.8 58.2 80.0 189.8 200.6 77.5 150.9 166.1 84.9 412.7 50.3 72.1 32.1 16.0 13.7 36.7 40.1 17.0 16.5 28.2 137.4 69.3 63.5 18.9 18.7 72.8 19.9 21.8 20.5 28.3 21.3 22.7 25.4 22.2 24.5 19.7 26.1 21.9 7.9 0.0 17.0 4.6 21.5 12.5 24.3 46.6 8.6 6.2 14.6 8.6 1.1 14.3 22.9 11.0 18.8 29.6 58.9 25.5 29.4 39.3 10.3 7.7 13.7 13.2 9.5 37.7 2.9 29.3 41.2 19.6 23.4 10.7 37.5 26.1 18.2 1.6 45.6 33.7 2.3 11.5 24.4 58.2 26.0 20.8 26.1 56.6 19.6 5.6 112.3 13.6 83.4 3.5 3.7 31.0 11.4 16.1 21.6 23.9 18.5 18.3 10.9 32.5 6.6 7.5 23.6 10.9 32.8 34.4 13.8 36.3 33.8 11.6 13.5 30.5 GABPB1 "E4TF1-47, GABPB, GABPB2" ENSG00000104064 "GA binding protein transcription factor subunit beta 1" Q06547 15 50275389-50355408 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019653, HPA067444" Supported Supported "Nucleoplasm,Cytoplasmic bodies" NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Cytoplasmic bodies" "HPA019653: AB_1849370, HPA067444: AB_2685842" "unprognostic (7.79e-3)" "unprognostic (2.42e-2)" "unprognostic (3.84e-1)" "unprognostic (1.92e-1)" "unprognostic (9.33e-2)" "unprognostic (3.99e-2)" "unprognostic (3.25e-2)" "unprognostic (5.65e-2)" "unprognostic (1.86e-2)" "unprognostic (8.94e-3)" "unprognostic (1.23e-1)" "unprognostic (4.54e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (3.18e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-1)" "unprognostic (3.93e-3)" 14.1 7.5 5.5 13.6 6.1 34.7 11.5 11.1 7.1 8.5 5.8 9.0 7.6 10.4 9.5 8.0 8.6 9.2 7.1 5.7 5.7 7.4 13.9 9.3 18.8 6.2 5.2 8.2 7.4 9.8 4.7 14.3 6.3 9.6 10.7 8.1 8.5 6.9 7.4 8.2 7.9 10.0 5.3 11.9 8.8 16.1 5.8 24.8 9.6 8.1 20.1 16.8 6.9 9.2 25.4 28.6 41.0 32.0 10.6 14.8 54.7 32.5 25.5 37.6 32.9 48.9 20.3 33.0 19.3 26.9 29.7 40.8 37.2 27.9 47.5 46.1 22.2 39.2 29.3 33.7 25.3 37.9 29.1 19.7 26.8 35.3 45.6 21.0 66.9 35.6 36.6 40.4 25.4 58.1 56.5 34.1 28.2 27.8 19.2 68.6 29.8 31.7 22.9 31.7 38.9 32.0 29.0 27.0 33.4 38.9 23.5 37.1 32.1 34.2 28.3 60.4 58.9 28.6 42.0 57.8 21.1 34.5 35.2 44.5 16.2 32.7 19.8 20.1 26.5 31.6 19.4 21.4 22.4 26.4 17.7 20.5 16.1 27.3 15.7 17.7 27.9 20.2 5.5 6.1 11.1 7.1 5.7 5.7 6.2 5.2 6.3 5.3 5.8 9.2 18.2 9.6 11.2 10.7 80.0 47.2 126.7 15.1 23.9 43.1 10.1 9.4 17.7 24.3 7.2 7.3 35.5 43.2 47.3 11.4 3.9 12.2 79.5 8.3 11.9 38.0 50.4 38.7 13.9 7.6 50.5 33.2 23.9 10.9 47.0 8.6 41.7 30.6 37.0 37.0 12.3 24.9 12.2 73.4 22.3 33.3 57.8 42.2 19.6 15.9 54.0 32.4 120.5 22.1 19.1 14.6 21.6 38.4 58.7 89.3 21.4 8.4 8.7 45.8 26.3 64.0 32.5 28.9 34.0 32.7 35.8 55.4 77.2 6.7 27.8 116.6 GAR1 NOLA1 ENSG00000109534 "GAR1 ribonucleoprotein" Q9NY12 4 109815510-109824740 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059098 Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA059098: AB_2683904" "unprognostic (9.72e-2)" "unprognostic (6.94e-2)" "unprognostic (3.04e-2)" "unprognostic (4.47e-2)" "unprognostic (2.40e-1)" "unprognostic (1.24e-2)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (4.17e-3)" "unprognostic (2.14e-2)" "unprognostic (2.45e-3)" "unprognostic (1.17e-1)" "unprognostic (5.11e-2)" "unprognostic (1.11e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-3)" 14.7 16.4 10.0 13.5 10.1 31.7 15.9 9.8 13.0 12.3 10.1 16.0 11.3 13.7 11.4 23.0 13.3 6.4 12.7 10.0 10.3 20.1 16.5 9.6 13.5 10.1 10.1 15.5 14.7 9.3 11.8 11.5 10.3 12.2 15.2 7.1 13.2 8.0 12.2 23.2 13.2 11.7 9.9 15.5 12.9 15.1 10.3 13.8 10.7 6.6 16.0 16.3 13.5 10.6 45.7 65.5 34.3 49.7 19.3 26.8 34.1 47.1 24.1 35.3 30.1 100.6 60.2 103.5 27.5 38.9 39.5 22.2 68.8 47.7 66.5 31.2 68.3 57.7 57.1 113.1 46.6 150.8 35.2 27.0 49.5 48.6 37.6 27.9 44.5 48.1 146.8 34.6 50.0 121.7 78.5 115.4 59.5 78.4 68.7 58.0 57.2 41.2 55.3 79.3 51.2 55.7 26.3 80.6 46.2 29.5 25.1 48.4 39.3 38.5 51.1 27.2 61.4 42.0 70.7 132.2 26.3 69.7 43.2 7.5 4.0 2.9 6.1 6.7 6.5 8.4 5.9 6.2 6.3 7.9 6.7 6.2 0.7 7.3 6.3 6.8 6.8 2.6 10.0 10.1 9.8 13.0 10.0 10.3 10.1 10.1 10.3 9.9 10.3 10.6 25.2 3.2 17.0 4.6 29.0 57.9 40.9 42.7 27.3 11.9 36.3 37.2 13.8 14.3 33.1 16.5 14.6 69.9 23.4 18.5 25.4 49.2 1.3 54.0 39.9 30.9 18.6 62.1 6.6 53.8 65.8 24.7 30.1 36.9 19.0 38.1 18.2 19.6 35.8 5.0 6.3 40.7 10.2 13.3 17.2 4.3 22.1 16.0 17.8 5.6 16.1 39.2 17.5 5.5 7.4 49.5 22.7 18.8 24.7 68.5 14.5 40.4 35.6 9.3 6.6 35.2 27.7 45.0 38.3 40.2 60.0 87.8 24.8 44.6 46.1 40.6 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GCC1 "FLJ22035, GCC1P, GCC88, MGC20706" ENSG00000179562 "GRIP and coiled-coil domain containing 1" Q96CN9 7 127580628-127593611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 102.7;Late spermatids: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019369, HPA021323" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA019369: AB_1849552, HPA021323: AB_1849554" "unprognostic (1.09e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-1)" "unprognostic (9.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.54e-2)" "unprognostic (1.83e-1)" "unprognostic (5.08e-2)" "unprognostic (4.81e-2)" "unprognostic (4.50e-3)" "unprognostic (1.17e-3)" "unprognostic (4.17e-3)" "unprognostic (1.22e-1)" "unprognostic (8.65e-2)" "unprognostic (9.96e-2)" 6.6 6.6 5.4 7.8 6.3 13.5 9.2 6.4 5.7 7.0 6.2 6.9 6.5 6.1 6.5 7.0 5.9 6.3 4.8 5.2 5.9 6.2 10.6 6.9 8.6 6.3 6.3 8.0 6.9 9.4 4.5 7.5 6.1 7.3 6.2 3.6 8.2 6.7 6.6 7.8 6.5 5.1 6.2 8.3 7.7 11.0 6.1 8.3 7.7 6.7 9.9 7.1 4.7 7.2 15.7 20.8 9.0 19.5 19.7 13.5 12.4 13.4 15.5 13.2 16.5 17.5 10.5 14.4 8.0 12.6 29.7 17.0 13.1 14.7 14.1 20.3 11.9 10.6 11.4 9.2 29.2 18.5 16.9 12.7 39.7 14.1 27.8 12.4 12.6 14.2 17.6 16.1 15.0 15.6 18.0 16.0 18.8 17.2 16.1 12.7 9.8 16.5 11.4 12.0 14.2 20.6 14.4 67.9 27.5 16.1 11.6 13.2 16.4 19.5 6.3 17.0 15.6 43.6 20.6 9.1 19.3 18.6 20.2 5.3 7.1 13.2 7.1 6.9 9.1 6.6 6.4 7.0 6.6 6.3 5.1 5.2 13.1 8.7 8.2 3.8 6.5 8.1 5.4 6.3 6.4 5.7 5.2 5.9 6.3 6.3 6.1 6.2 6.1 7.2 4.8 12.8 7.7 0.0 9.6 10.6 5.0 2.7 12.0 4.1 11.5 6.1 3.6 4.3 3.7 3.7 4.2 7.2 7.3 10.0 5.9 5.1 102.7 4.3 5.5 6.7 7.2 8.2 0.0 6.4 4.6 5.0 8.6 6.8 1.3 5.9 5.0 7.4 5.2 11.8 0.0 8.2 2.0 10.1 8.3 131.7 5.3 7.6 12.4 0.0 6.9 4.9 5.2 0.0 0.0 5.9 6.6 3.8 6.3 5.4 6.0 4.5 2.4 5.9 6.6 5.9 6.5 7.8 4.6 6.3 10.4 10.4 8.8 5.8 5.8 5.4 GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 53.7;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in some" "dendritic cells: 14.2;Intestinal goblet cells: 12.4;NK-cells: 11.3;Plasma cells: 8.6;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 61.9;HMC-1: 47.5;NB-4: 64.7;THP-1: 127.7;U-937: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB011197: AB_532302" "unprognostic (5.67e-4)" "unprognostic (8.67e-3)" "prognostic favorable (5.68e-5)" "unprognostic (4.88e-3)" "unprognostic (3.57e-2)" "unprognostic (5.86e-3)" "unprognostic (2.06e-1)" "unprognostic (3.87e-3)" "unprognostic (1.26e-3)" "unprognostic (4.47e-3)" "unprognostic (5.20e-2)" "unprognostic (1.72e-1)" "unprognostic (6.80e-6)" "unprognostic (2.63e-1)" "unprognostic (8.27e-2)" "unprognostic (3.97e-1)" "unprognostic (4.37e-2)" 1.0 0.5 0.1 5.1 0.2 53.7 0.9 0.1 0.1 0.6 0.3 3.6 4.7 0.6 0.5 0.5 0.7 1.9 0.3 0.1 0.1 0.5 1.0 2.8 6.9 0.3 0.1 0.5 9.4 0.2 0.5 0.2 0.2 0.8 4.5 0.0 1.0 0.3 0.2 0.3 5.7 0.4 0.2 7.0 3.2 0.9 0.2 31.2 0.9 0.0 4.4 1.7 0.6 0.2 1.4 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.1 0.1 1.0 10.3 0.1 0.7 0.0 0.5 0.4 1.2 0.0 0.2 0.0 2.5 1.6 0.2 5.3 0.1 61.9 47.5 0.0 0.0 0.1 0.1 0.3 0.1 17.1 0.4 15.3 0.1 2.1 39.5 64.7 0.0 0.1 0.2 7.8 2.7 3.4 0.0 0.7 0.1 0.1 0.3 0.1 0.3 0.1 0.0 127.7 0.0 0.0 1.5 0.1 0.2 22.2 1.6 4.0 0.0 261.3 0.0 0.0 0.0 0.4 2.1 0.0 1.0 0.0 0.9 1.4 0.0 0.0 0.3 1.9 0.0 0.1 0.0 0.8 0.3 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.2 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 14.2 1.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.1 0.2 0.0 0.1 1.4 0.0 0.1 0.0 0.1 12.4 0.0 0.8 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 11.3 0.0 0.1 0.4 0.0 0.0 8.6 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.2 0.5 3.9 0.0 0.0 0.0 16.4 0.1 0.4 0.0 GGNBP2 "DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403" ENSG00000278311 "Gametogenetin binding protein 2" Q9H3C7 17 36544912-36589848 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 467.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018914, HPA073392" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA018914: AB_2294667, HPA073392: AB_2686599" "unprognostic (2.68e-1)" "unprognostic (5.19e-2)" "unprognostic (2.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (6.12e-2)" "unprognostic (1.88e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (3.29e-2)" "unprognostic (3.82e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (3.75e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (1.95e-2)" 41.7 30.5 23.8 29.5 23.9 79.9 35.3 26.4 30.0 32.5 24.6 38.9 33.8 34.0 26.6 33.9 34.7 25.2 31.0 24.1 25.5 31.2 36.6 33.5 49.7 25.1 25.7 40.0 35.3 31.5 26.7 27.1 25.9 27.8 30.7 26.8 33.2 23.9 52.7 40.5 44.0 27.5 23.6 39.4 34.8 60.2 24.6 36.6 29.4 32.2 46.5 37.2 34.7 26.1 48.0 49.4 45.8 38.9 53.5 63.9 33.0 60.0 48.1 44.4 44.2 48.6 34.5 64.5 37.2 47.7 44.4 46.9 37.2 55.6 58.1 38.9 36.1 36.2 55.1 43.7 55.1 63.1 47.1 62.3 68.4 45.2 61.4 56.6 38.9 46.2 51.2 62.0 62.5 29.5 65.6 51.2 13.9 31.0 26.1 44.3 60.9 42.8 58.6 93.2 37.1 32.3 58.1 33.5 97.1 46.2 63.0 64.2 39.9 62.4 43.0 41.5 62.4 42.2 50.0 48.7 40.9 34.6 38.6 42.8 31.6 67.8 37.1 35.9 43.6 56.6 46.9 41.5 42.0 48.5 66.0 62.0 44.9 40.4 39.9 84.1 50.1 20.8 23.8 23.9 26.4 30.0 24.1 25.5 25.1 25.7 25.9 23.6 24.6 26.1 85.0 67.3 84.2 38.5 110.2 96.0 98.9 128.8 111.5 70.2 58.9 46.9 81.1 60.1 118.6 31.3 37.5 82.4 132.3 94.7 52.8 74.0 467.4 87.3 84.2 82.2 57.4 71.1 46.9 68.5 77.4 86.6 56.1 104.3 97.5 52.2 65.0 64.7 73.5 57.2 43.3 79.6 101.7 77.9 66.7 130.6 79.6 84.7 58.7 33.7 103.0 71.8 94.7 29.1 48.6 73.2 74.2 72.2 84.4 83.9 124.9 63.6 107.0 71.5 59.2 99.0 114.9 335.2 98.7 91.9 96.5 95.6 117.8 53.5 97.4 102.4 GID8 "bA305P22.1, C20orf11, FLJ20602, TWA1" ENSG00000101193 "GID complex subunit 8 homolog" Q9NWU2 20 62938147-62948475 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049929, HPA055047" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Cell Junctions" "HPA049929: AB_2680957, HPA055047: AB_2682682" "unprognostic (1.35e-1)" "unprognostic (4.06e-2)" "unprognostic (5.90e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.19e-1)" "unprognostic (8.25e-2)" "unprognostic (3.88e-2)" "unprognostic (4.58e-2)" "unprognostic (2.16e-1)" "unprognostic (1.83e-1)" "unprognostic (2.72e-2)" "unprognostic (1.43e-1)" "prognostic favorable (3.22e-4)" "unprognostic (3.97e-1)" "unprognostic (1.43e-1)" "unprognostic (2.01e-1)" "unprognostic (6.87e-2)" 12.5 13.3 18.8 13.5 18.3 39.2 17.1 18.7 18.3 19.1 16.7 16.6 13.8 16.3 16.8 41.8 20.1 11.1 14.2 19.2 18.6 17.2 24.7 12.7 20.7 17.8 18.4 26.3 20.4 19.0 15.9 13.0 17.4 16.2 14.3 13.0 17.1 14.8 14.8 30.5 15.5 12.5 18.8 16.9 18.1 13.7 19.2 25.3 18.4 13.2 23.1 15.6 22.5 18.3 39.9 25.0 36.6 33.2 29.5 23.1 35.8 21.8 18.2 61.1 27.5 121.4 37.9 49.9 36.5 28.4 25.1 45.2 33.9 45.3 36.9 13.4 16.6 46.5 32.8 58.6 23.2 54.5 37.7 25.6 49.4 26.4 30.4 22.2 30.1 32.5 36.3 21.0 21.3 56.0 65.3 48.4 37.0 66.1 37.0 51.1 68.8 29.9 22.5 55.4 38.0 31.0 51.5 49.9 32.8 27.0 69.5 51.9 30.6 36.4 45.4 28.8 29.9 21.9 27.0 51.2 24.6 26.2 23.5 5.3 9.5 15.4 9.8 8.3 11.6 7.4 10.4 11.1 8.9 8.2 11.2 12.7 13.5 12.3 7.7 6.7 9.9 8.1 18.8 18.3 18.7 18.3 19.2 18.6 17.8 18.4 17.4 18.8 19.2 18.3 33.5 19.2 27.4 11.4 42.7 51.6 46.9 76.6 50.1 23.1 56.4 53.0 30.9 52.9 46.5 40.5 6.2 101.7 48.6 57.3 41.1 44.7 19.1 46.4 27.4 37.7 45.0 71.1 17.7 40.4 105.1 35.1 27.0 40.1 26.6 24.4 46.4 77.7 51.8 16.8 15.0 50.1 50.8 47.9 46.4 19.4 32.9 42.9 24.9 11.2 62.1 28.3 51.5 11.6 14.4 40.8 39.2 42.2 44.0 68.2 55.7 42.5 38.8 16.5 13.1 34.1 30.7 49.1 57.9 82.1 79.8 156.9 45.8 21.6 52.1 71.7 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GMEB1 "P96PIF, PIF96" ENSG00000162419 "Glucocorticoid modulatory element binding protein 1" Q9Y692 1 28668778-28719353 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044811, HPA052975" Supported Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA044811: AB_10959666, HPA052975: AB_2682003" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" "unprognostic (2.49e-2)" "prognostic favorable (1.94e-4)" "unprognostic (2.71e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.91e-7)" "unprognostic (1.42e-2)" "unprognostic (1.41e-1)" "unprognostic (6.88e-2)" "unprognostic (1.39e-1)" "unprognostic (3.38e-2)" "unprognostic (8.41e-2)" "unprognostic (4.79e-3)" "unprognostic (3.44e-1)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" 4.7 3.0 2.3 5.7 2.2 13.6 4.3 5.9 3.1 5.1 3.1 4.4 2.9 4.9 3.0 5.2 4.4 4.2 3.1 2.5 1.9 3.6 3.4 4.3 6.7 2.5 2.2 5.6 4.1 3.3 3.7 5.7 2.5 3.5 4.4 5.6 3.4 3.1 5.3 5.0 4.4 4.8 1.9 5.5 4.1 6.0 2.6 10.6 3.5 4.4 8.0 4.3 4.4 3.1 12.1 8.5 14.1 12.9 4.6 8.5 10.0 12.5 9.0 7.9 11.7 2.7 9.4 22.1 6.5 11.7 4.7 4.6 12.7 9.7 10.2 25.4 7.9 20.4 8.9 5.2 6.9 17.1 10.2 6.8 6.8 19.2 12.3 6.9 11.1 10.8 12.6 17.1 9.6 10.5 10.7 5.7 18.9 8.0 5.7 7.2 9.7 10.3 6.0 9.6 10.4 8.6 12.1 8.0 8.1 9.4 6.1 8.7 11.2 5.4 13.1 9.3 17.0 7.6 13.8 12.1 6.6 15.8 8.7 8.1 5.4 9.9 6.7 7.0 5.1 4.0 6.5 7.9 6.3 6.0 5.3 5.5 7.6 7.5 9.0 4.6 6.0 4.6 2.3 2.2 5.9 3.1 2.5 1.9 2.5 2.2 2.5 1.9 2.6 3.1 12.9 6.4 20.0 3.9 20.5 17.0 19.9 8.6 8.6 23.6 9.0 10.2 4.0 10.0 11.0 14.7 12.5 14.1 17.7 12.7 5.9 10.9 13.3 10.1 12.5 13.2 7.8 26.7 7.0 11.1 16.6 10.0 9.2 16.3 28.5 12.8 16.8 6.1 10.7 25.2 5.9 13.1 10.2 13.4 7.9 2.8 9.6 12.2 1.8 4.7 14.8 17.5 29.9 5.0 9.2 11.5 14.1 7.9 11.5 12.4 8.5 5.7 7.1 24.7 19.7 18.3 13.0 34.8 28.6 8.3 16.8 32.3 19.5 13.2 11.0 19.6 GPATCH2L "C14orf118, FLJ10033, FLJ20689" ENSG00000089916 "G-patch domain containing 2 like" Q9NWQ4 14 76151916-76254342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018856 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA018856: AB_1845553" "unprognostic (5.98e-2)" "unprognostic (1.44e-2)" "unprognostic (7.07e-2)" "unprognostic (1.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.59e-2)" "unprognostic (6.63e-3)" "unprognostic (1.81e-2)" "unprognostic (2.89e-2)" "unprognostic (2.70e-1)" "unprognostic (2.05e-2)" "unprognostic (5.60e-2)" "unprognostic (5.81e-2)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (8.09e-2)" "unprognostic (1.81e-1)" 9.9 8.9 7.5 12.1 10.1 37.5 9.7 10.7 9.7 8.9 11.4 9.9 8.5 10.5 9.5 11.3 8.0 12.2 13.3 7.8 10.2 8.9 6.8 10.7 12.1 9.9 8.9 10.4 8.7 9.2 6.9 11.3 9.4 9.8 10.8 15.5 8.2 9.8 12.1 9.0 9.2 11.9 9.9 10.8 9.3 13.8 8.8 11.6 9.7 14.0 12.1 10.5 9.3 12.8 18.7 24.0 19.2 15.3 11.0 17.0 15.7 21.7 15.0 20.7 20.1 16.0 30.8 22.2 12.6 16.8 16.8 22.0 23.4 14.2 36.6 24.7 12.9 19.5 26.1 10.1 14.2 13.7 27.6 17.6 12.6 17.8 23.0 16.2 21.9 18.1 20.6 30.6 18.6 30.6 18.3 17.7 24.2 11.1 17.5 20.3 23.2 11.5 14.7 37.0 15.5 19.2 24.5 21.6 12.0 19.7 25.2 21.2 24.0 26.7 15.3 14.9 16.5 30.7 31.3 29.2 21.4 18.4 28.0 5.3 7.3 7.9 3.5 6.6 3.0 6.3 1.9 5.2 7.2 5.3 4.2 3.0 5.6 5.6 4.8 5.6 4.5 3.7 7.5 10.1 10.7 9.7 7.8 10.2 9.9 8.9 9.4 9.9 8.8 12.8 35.3 16.0 18.2 48.0 30.2 23.3 37.4 26.0 22.2 100.0 19.9 21.2 46.3 18.6 25.2 18.4 104.3 16.2 36.8 18.8 3.9 20.0 151.4 28.9 46.2 38.2 47.8 17.1 76.0 13.3 12.7 36.6 21.9 54.5 43.7 48.2 29.3 11.6 25.2 158.2 67.0 19.3 24.4 43.0 48.9 138.9 24.8 43.5 23.2 59.0 47.7 42.3 43.3 82.0 75.0 30.4 29.4 37.6 24.6 56.9 40.2 13.5 24.4 122.7 26.3 55.0 41.7 56.6 27.2 18.7 27.3 17.4 31.2 34.9 20.6 42.6 GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB037303: AB_477173, HPA036793: AB_2675318, HPA036794: AB_10672230" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (5.64e-2)" "prognostic unfavorable (2.88e-5)" "unprognostic (2.57e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.50e-2)" "unprognostic (8.27e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.34e-1)" "unprognostic (1.21e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" 22.8 22.8 19.3 20.3 19.8 34.1 26.4 19.9 26.1 18.1 19.5 22.7 19.9 19.1 19.9 25.5 21.0 18.6 21.3 19.4 21.6 26.3 24.6 18.6 28.7 22.5 22.6 18.4 22.8 25.9 16.6 26.5 21.8 17.7 25.6 24.9 21.5 16.9 32.4 24.8 19.6 22.4 19.6 22.2 20.6 25.5 21.9 30.1 22.8 27.2 30.3 24.0 19.5 21.2 94.6 53.3 48.8 35.4 44.3 44.8 48.7 52.0 50.5 70.7 52.1 58.0 47.4 58.8 49.2 56.4 65.4 39.5 67.6 63.4 71.5 55.4 47.6 66.8 38.3 70.7 57.3 100.0 33.7 46.7 54.8 72.6 67.1 49.4 75.2 51.5 84.7 53.5 84.1 54.2 60.3 75.1 83.4 70.9 50.7 60.2 144.4 61.0 57.9 53.5 42.9 67.6 57.2 61.5 58.4 44.7 37.1 56.0 62.9 61.5 91.1 30.9 122.7 60.8 71.8 156.9 88.0 85.0 51.8 92.4 61.3 55.1 79.1 71.6 86.0 74.6 72.2 92.0 89.7 68.7 63.8 78.2 9.3 106.1 72.1 46.8 79.2 82.3 19.3 19.8 19.9 26.1 19.4 21.6 22.5 22.6 21.8 19.6 21.9 21.2 17.6 12.8 10.4 2.3 18.7 21.7 21.7 28.2 10.8 9.2 14.8 11.8 11.8 14.3 19.7 14.7 4.2 43.5 28.8 9.5 23.5 46.4 86.3 20.5 14.1 17.3 17.4 18.7 6.6 36.3 46.2 14.3 9.7 21.7 24.7 17.7 17.5 10.2 33.4 11.8 6.6 13.0 20.3 20.1 26.8 76.0 14.9 17.6 23.2 2.8 28.9 15.0 27.8 5.0 5.0 46.3 13.5 10.9 11.2 20.1 16.2 20.8 14.3 10.9 13.1 13.2 19.0 36.6 23.4 13.6 18.6 33.1 31.0 20.2 20.0 18.9 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 GTF2B TFIIB ENSG00000137947 "General transcription factor IIB" Q00403 1 88852633-88891944 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061626 Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" "HPA061626: AB_2684570" "prognostic favorable (4.81e-4)" "unprognostic (5.21e-2)" "unprognostic (3.94e-3)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" "unprognostic (2.43e-1)" "unprognostic (1.08e-2)" "unprognostic (2.65e-2)" "unprognostic (4.37e-3)" "unprognostic (3.37e-1)" "unprognostic (1.37e-2)" "unprognostic (3.13e-1)" "unprognostic (1.42e-2)" "unprognostic (1.10e-2)" "unprognostic (1.40e-1)" "unprognostic (4.06e-3)" "unprognostic (3.74e-2)" 25.3 26.4 14.8 18.8 15.7 62.2 28.3 16.4 24.0 22.9 17.7 22.6 17.9 21.8 30.3 26.3 22.7 23.8 15.7 15.5 16.5 22.9 32.6 22.0 28.9 15.5 15.9 26.3 23.3 22.7 20.3 25.2 15.7 18.1 23.1 17.9 22.9 16.3 23.1 28.3 23.9 20.7 16.2 28.7 23.0 16.3 15.1 40.2 21.2 18.5 31.3 31.5 23.7 17.0 40.0 13.6 34.6 18.8 49.8 34.4 42.9 32.1 39.4 44.1 46.4 17.9 24.3 45.5 37.8 28.0 53.3 22.0 36.8 32.1 38.3 42.8 34.3 48.6 21.2 32.1 31.9 56.8 28.7 30.0 32.1 38.2 21.7 33.4 25.1 41.1 43.1 33.6 47.0 12.6 54.9 46.7 28.8 35.4 29.3 34.4 46.8 34.2 47.0 47.2 26.7 22.4 28.5 35.4 57.8 30.7 15.9 51.1 22.3 19.2 24.0 35.0 38.8 35.1 29.9 62.6 12.8 48.8 16.7 91.2 49.3 82.1 45.9 57.1 53.2 57.8 52.1 50.5 62.5 48.2 62.9 53.9 99.7 54.9 60.4 40.5 70.1 50.9 14.8 15.7 16.4 24.0 15.5 16.5 15.5 15.9 15.7 16.2 15.1 17.0 106.6 6.4 29.7 13.7 114.9 46.3 75.4 63.3 58.6 14.6 39.7 104.9 12.3 21.5 45.6 11.0 2.1 74.0 122.3 39.1 39.2 49.2 22.9 53.9 28.4 30.3 20.3 51.1 22.7 38.6 60.0 53.0 41.8 29.8 48.9 30.2 16.8 17.6 40.5 18.5 21.4 30.5 52.9 32.3 42.5 7.9 36.4 93.4 28.4 22.5 40.3 30.7 33.0 18.1 25.2 49.9 70.5 29.3 74.3 27.8 26.9 47.4 55.2 18.5 13.1 86.6 65.0 24.2 29.0 40.1 50.0 150.1 122.8 34.5 22.7 79.4 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 H1-10 "H1FX, H1X, MGC15959, MGC8350" ENSG00000184897 "H1.10 linker histone" Q92522 3 129314771-129316286 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1004.3" "Cell type enhanced" "Detected in some" "Adipocytes: 188.4;Cytotrophoblasts: 66.8;dendritic cells: 73.2;Extravillous trophoblasts: 114.2;Hofbauer cells: 93.4;Plasma cells: 148.6;Syncytiotrophoblasts: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 937.8" "Low region specificity" "Detected in all" "CAB012235, HPA040099, HPA068431" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB012235: , HPA040099: AB_2676846, HPA068431: " "unprognostic (1.01e-2)" "unprognostic (1.12e-2)" "unprognostic (4.13e-2)" "unprognostic (8.48e-2)" "unprognostic (6.94e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (1.46e-2)" "unprognostic (1.16e-1)" "unprognostic (5.51e-2)" "unprognostic (5.28e-3)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" "unprognostic (2.85e-1)" "unprognostic (3.24e-1)" "unprognostic (2.50e-2)" 121.4 54.7 39.9 42.6 43.9 1004.3 145.0 60.6 68.6 162.4 25.2 125.0 44.6 143.1 9.2 107.8 142.2 13.9 82.0 43.1 48.4 162.7 100.1 115.8 44.3 29.5 26.0 168.9 100.0 30.1 112.6 25.4 25.1 124.5 11.9 13.9 98.7 20.8 110.7 258.4 106.7 13.2 27.8 127.7 115.7 40.9 38.2 131.5 94.4 12.3 18.3 130.9 140.7 46.4 141.8 73.4 135.8 59.3 13.6 16.1 129.1 60.5 43.5 70.4 74.3 44.5 75.5 17.8 65.5 21.6 47.2 139.1 57.3 39.0 10.8 129.4 111.7 53.8 55.5 61.1 57.3 62.6 14.1 32.4 51.9 28.7 64.7 32.0 40.7 241.7 83.7 308.5 10.0 147.9 290.9 124.1 127.2 25.8 81.6 207.4 58.1 170.9 22.1 29.1 216.0 250.1 64.1 31.7 196.3 26.1 124.1 125.1 40.9 54.4 283.5 53.5 51.2 937.8 385.2 156.9 44.5 58.6 61.1 0.5 5.5 17.8 4.4 4.2 4.0 5.7 6.7 5.2 7.9 5.3 8.4 4.3 1.2 5.2 3.9 11.4 6.1 2.4 39.9 43.9 60.6 68.6 43.1 48.4 29.5 26.0 25.1 27.8 38.2 46.4 188.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 66.8 73.2 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 114.2 46.9 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.0 0.0 68.4 17.6 0.0 0.0 0.0 H3-3A "H3.3A, H3F3, H3F3A" ENSG00000163041 "H3.3 histone A" P84243 1 226061851-226072019 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 600.6;Cytotrophoblasts: 1411.0;Extravillous trophoblasts: 2181.9;Hofbauer cells: 1487.3;Syncytiotrophoblasts: 1616.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4487.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 4487.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011481, CAB037178, HPA042570" Supported Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011481: AB_880446, CAB037178: AB_532248, HPA042570: AB_2678056" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-3)" "unprognostic (2.83e-2)" "unprognostic (3.74e-1)" "unprognostic (9.83e-3)" "unprognostic (4.71e-2)" "unprognostic (1.77e-3)" "unprognostic (3.69e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (3.66e-2)" "unprognostic (8.03e-3)" "unprognostic (2.21e-3)" "unprognostic (6.03e-2)" 409.6 440.4 240.3 662.2 255.8 2033.8 594.8 262.4 343.4 544.2 244.8 708.3 655.2 492.2 721.3 595.8 565.3 487.7 500.1 229.1 252.3 457.9 537.9 438.9 793.5 273.8 247.1 453.0 435.4 499.7 270.0 490.0 274.4 474.8 790.0 271.6 586.9 382.0 337.1 617.2 672.5 468.6 272.4 539.1 547.2 255.9 246.8 1239.6 480.5 435.5 894.6 597.6 409.0 295.7 751.2 417.0 1589.6 910.2 432.9 498.9 1186.2 337.3 416.2 547.8 429.0 446.2 1214.5 715.3 731.0 427.9 273.5 684.4 802.4 631.9 535.0 445.9 1371.0 889.5 569.9 595.2 427.8 901.4 1026.6 465.6 715.8 385.3 502.1 743.0 826.8 915.7 1271.3 1125.2 626.2 433.8 1791.8 1504.6 2163.0 1881.1 815.7 1286.9 1110.4 1871.4 1159.6 784.3 1542.1 2279.8 991.0 1227.4 842.4 882.3 1399.1 2103.7 471.4 397.1 527.2 532.6 1024.0 523.6 643.4 1178.4 380.2 853.2 874.1 869.5 1043.6 1486.1 378.9 830.2 385.9 722.1 405.2 415.8 791.8 661.7 375.0 423.1 4487.2 442.5 945.8 635.2 636.8 1364.8 240.3 255.8 262.4 343.4 229.1 252.3 273.8 247.1 274.4 272.4 246.8 295.7 600.6 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 1411.0 449.2 0.0 0.0 0.0 0.0 0.0 0.0 109.5 0.0 0.0 0.0 0.0 2181.9 188.0 0.0 0.0 0.0 0.0 0.0 0.0 1487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 1616.9 75.3 0.0 0.0 0.0 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 HAUS3 "C4orf15, dgt3, IT1, MGC4701" ENSG00000214367 "HAUS augmin like complex subunit 3" Q68CZ6 4 2078998-2242276 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040649, HPA048190" Approved Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040649: AB_2677060, HPA048190: AB_2680308" "unprognostic (4.22e-2)" "unprognostic (1.50e-1)" "unprognostic (6.30e-2)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (2.57e-3)" "unprognostic (7.63e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (2.79e-2)" "unprognostic (2.15e-2)" "unprognostic (2.79e-1)" "unprognostic (4.40e-2)" "prognostic favorable (4.78e-5)" 9.6 8.6 3.5 7.5 3.5 27.5 8.9 9.0 4.6 8.1 1.9 8.3 6.5 7.3 4.9 8.0 7.2 4.2 5.8 3.4 3.2 6.2 7.4 9.0 10.2 3.4 3.4 7.3 10.5 4.0 5.6 6.5 3.3 8.5 5.3 5.8 8.5 4.5 7.4 8.9 9.2 4.7 2.3 12.0 9.0 10.7 3.4 8.6 7.4 4.6 8.3 7.1 7.7 4.3 9.8 4.7 14.2 13.0 5.5 8.5 12.8 14.3 6.0 12.7 10.6 9.5 12.5 18.9 6.5 5.7 14.3 9.3 11.9 7.2 15.9 6.8 6.9 12.5 13.1 7.0 4.5 11.6 11.2 4.3 10.2 11.0 5.8 6.6 10.3 8.8 22.0 21.2 12.5 5.4 19.6 19.5 11.2 8.5 12.3 13.9 12.4 10.4 6.3 6.7 18.4 10.0 10.1 7.6 8.4 10.5 15.7 7.8 8.5 18.1 7.8 11.1 17.0 11.2 10.6 16.9 8.8 16.8 12.0 9.6 4.2 12.2 7.9 5.8 10.1 5.5 8.2 8.9 3.8 9.1 9.5 8.9 4.7 10.7 6.9 6.8 12.0 6.6 3.5 3.5 9.0 4.6 3.4 3.2 3.4 3.4 3.3 2.3 3.4 4.3 15.5 3.2 4.8 0.0 15.8 12.6 5.0 6.4 15.4 11.9 9.3 8.8 5.8 7.2 10.3 3.7 12.5 7.3 24.0 3.9 1.9 7.4 11.8 8.9 11.8 9.4 7.2 23.1 0.0 5.7 11.7 9.6 4.6 8.3 13.3 12.1 6.8 3.7 7.2 25.2 0.0 6.4 12.2 5.4 9.3 6.4 9.9 10.4 12.4 0.0 7.9 6.5 16.5 0.0 0.0 5.3 1.8 8.6 22.5 5.1 5.8 2.6 5.4 12.5 0.0 12.3 17.7 34.4 25.3 10.5 7.7 5.1 26.5 10.1 5.8 3.0 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HERPUD2 FLJ22313 ENSG00000122557 "HERPUD family member 2" Q9BSE4 7 35632659-35697459 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 329.7;Late spermatids: 660.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015630, HPA076087" Approved Approved "Nucleoli,Nucleoli rim" No No "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "HPA015630: AB_1850609, HPA076087: AB_2686774" "unprognostic (1.85e-2)" "unprognostic (5.31e-3)" "unprognostic (2.76e-1)" "unprognostic (3.79e-1)" "unprognostic (3.46e-1)" "unprognostic (2.73e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (2.30e-2)" "unprognostic (7.95e-2)" "unprognostic (5.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" 17.4 13.6 17.1 19.7 19.8 33.6 14.7 18.6 19.1 17.3 19.4 16.2 15.9 21.0 15.0 21.2 16.6 19.3 16.6 16.4 16.2 16.1 23.5 21.1 21.5 17.9 17.3 32.6 28.9 14.3 10.3 17.7 17.2 15.1 16.8 23.0 14.8 12.8 16.4 23.1 16.8 17.9 16.5 24.3 17.1 26.0 18.2 18.0 23.3 14.4 19.8 18.3 16.0 21.2 36.4 13.1 25.5 28.2 34.0 26.7 18.0 25.4 31.3 14.6 16.9 15.3 39.3 28.2 35.0 28.9 58.4 41.7 12.7 16.8 22.4 17.0 16.3 18.5 17.1 12.6 29.3 17.2 20.9 31.5 31.4 18.1 29.6 32.9 24.8 32.9 28.2 34.8 27.3 19.3 21.1 31.3 19.5 23.8 15.9 22.6 34.0 20.0 20.4 16.4 23.8 37.9 35.3 30.5 23.0 42.2 31.5 25.0 28.9 26.1 29.4 24.5 19.9 45.0 57.4 28.0 24.9 27.9 48.0 8.8 7.4 23.2 11.0 8.4 12.6 4.8 9.7 12.0 6.3 7.0 6.1 8.6 12.4 13.7 11.3 3.8 10.1 5.7 17.1 19.8 18.6 19.1 16.4 16.2 17.9 17.3 17.2 16.5 18.2 21.2 30.8 25.6 17.1 66.6 48.1 16.8 17.0 9.0 20.5 14.1 12.0 12.7 12.8 20.0 11.8 5.5 8.4 17.6 57.4 19.8 17.6 25.0 329.7 20.5 19.3 21.5 14.3 27.4 25.8 28.9 25.0 23.2 24.5 25.5 36.8 24.4 24.3 21.8 17.5 11.8 44.2 11.8 12.2 25.1 20.0 660.5 27.4 27.3 23.2 31.9 28.5 24.0 40.2 37.2 34.7 34.7 16.0 25.2 42.8 17.9 24.3 12.7 11.1 13.9 13.1 26.5 26.6 45.0 18.7 19.9 15.8 31.1 83.2 16.6 14.2 20.3 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.0;Early spermatids: 18.4;Glandular and luminal cells: 17.3;Granulosa cells: 29.7;Pancreatic endocrine cells: 19.9;Smooth muscle cells: 33.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 324.4;hTERT-RPE1: 232.6;SuSa: 216.1" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" 0.4 0.0 0.3 0.3 0.2 4.9 0.2 0.7 0.5 1.1 0.0 2.1 1.3 0.4 0.0 0.3 1.2 0.3 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.6 0.9 0.0 0.4 0.2 0.2 0.0 2.4 0.5 0.1 0.1 1.5 0.4 1.0 0.1 0.1 0.1 1.1 3.8 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.4 47.9 21.4 324.4 45.8 15.0 82.0 0.1 148.5 68.5 26.0 25.8 28.1 19.8 0.0 92.3 7.0 120.0 20.5 54.2 129.3 123.8 0.2 56.2 0.2 0.7 169.3 8.4 4.7 0.4 62.7 8.0 55.2 98.4 232.6 105.0 0.2 0.1 0.6 149.9 0.2 0.4 27.8 190.3 4.6 89.2 12.7 16.1 0.1 68.9 0.3 0.0 0.0 0.1 0.1 85.0 216.1 0.5 0.7 120.8 89.5 26.9 71.2 45.3 0.2 0.2 0.4 112.0 0.3 21.4 1.4 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.6 0.1 0.0 0.0 0.3 0.2 0.7 0.5 0.2 0.1 0.4 0.2 0.2 0.1 0.2 0.4 0.0 0.0 1.1 5.9 0.2 0.0 3.6 16.0 2.8 0.0 0.1 0.1 1.7 0.0 3.0 0.0 0.0 0.8 0.0 5.0 0.0 2.5 18.4 10.4 0.8 0.6 0.0 7.4 0.8 0.8 0.5 2.3 3.1 17.3 0.0 29.7 0.7 0.0 9.0 0.0 0.9 5.1 4.1 0.0 0.0 9.0 0.3 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.9 19.9 4.5 0.0 0.4 5.5 4.0 0.3 7.3 0.0 0.0 1.1 33.7 13.5 0.6 0.3 0.1 0.8 0.3 0.3 8.4 1.1 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 HMGN2 HMG17 ENSG00000198830 "High mobility group nucleosomal binding domain 2" P05204 1 26472440-26476642 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB018371, HPA077364" Supported Supported Nucleoplasm,Nucleoli NA NA 640000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB018371: , HPA077364: AB_2686835" "unprognostic (3.10e-2)" "unprognostic (6.88e-2)" "unprognostic (3.10e-3)" "unprognostic (4.13e-2)" "unprognostic (4.06e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (2.36e-1)" "unprognostic (2.44e-3)" "unprognostic (2.86e-2)" "unprognostic (1.05e-3)" "unprognostic (5.23e-3)" "prognostic unfavorable (3.92e-4)" "unprognostic (3.00e-2)" "unprognostic (2.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.15e-1)" 216.3 225.6 180.2 254.5 187.3 1137.3 234.8 179.6 251.3 328.1 162.5 280.3 176.3 283.8 359.3 291.1 293.4 142.9 192.5 170.6 183.1 259.7 212.9 259.2 436.5 185.1 178.8 394.6 252.5 160.4 328.7 214.9 188.4 281.6 301.1 285.0 217.1 162.8 251.8 242.8 270.0 235.8 188.7 324.3 224.7 160.4 175.8 916.1 306.1 133.5 534.0 245.1 250.7 211.6 1074.5 304.8 1192.5 496.5 112.0 251.6 390.8 517.2 331.2 1089.4 835.7 305.8 1073.1 1107.2 443.1 482.3 338.4 627.8 1564.6 565.6 1001.7 684.2 906.7 1222.2 401.5 360.2 197.7 2793.6 738.7 254.9 303.4 602.1 369.1 245.1 541.7 866.8 964.3 643.0 623.0 690.8 1906.1 1363.3 922.7 1463.0 619.6 1384.3 1598.6 776.5 380.3 278.6 1064.5 641.1 1384.3 498.7 651.4 304.9 759.0 1508.9 322.3 536.9 920.4 977.1 943.6 641.2 899.2 1266.9 338.9 2989.0 1056.9 331.8 530.8 1430.5 279.2 622.3 267.3 532.2 379.7 343.3 531.5 505.6 412.4 337.7 462.4 355.5 690.4 704.7 746.7 1084.6 180.2 187.3 179.6 251.3 170.6 183.1 185.1 178.8 188.4 188.7 175.8 211.6 128.7 342.9 394.4 28.1 459.3 288.6 323.8 383.2 211.1 180.2 353.0 241.3 93.4 221.6 314.8 261.1 141.8 898.7 325.2 227.2 371.7 218.4 204.3 328.9 291.1 190.3 576.9 980.4 14.4 268.7 606.4 435.4 263.5 278.1 383.0 375.0 185.6 147.5 763.0 94.2 22.2 564.5 193.3 434.3 467.9 53.5 185.8 477.5 227.7 15.0 655.6 376.0 399.6 15.1 36.9 93.7 304.4 151.9 669.5 250.4 238.0 320.4 495.6 370.2 124.9 249.0 325.7 306.4 412.0 585.8 213.4 923.4 369.5 351.9 613.2 314.0 HMGXB4 "HMG2L1, THC211630" ENSG00000100281 "HMG-box containing 4" Q9UGU5 22 35257452-35295807 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000725, HPA076681" Approved Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA000725: AB_1079073, HPA076681: " "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.24e-5)" "unprognostic (4.81e-2)" "unprognostic (1.93e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.85e-2)" "unprognostic (8.25e-3)" "unprognostic (6.67e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.62e-1)" "unprognostic (8.71e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" 7.9 4.7 5.1 7.8 6.5 23.4 8.1 6.5 7.2 6.7 3.7 6.6 6.4 11.6 3.7 8.6 7.6 7.0 6.5 5.3 5.8 4.1 5.1 5.6 7.5 5.9 5.3 14.0 7.0 8.2 2.2 9.0 5.8 7.4 7.4 8.5 6.7 6.2 7.2 6.7 6.7 9.5 4.9 6.3 5.0 7.9 6.1 11.3 6.7 7.2 7.7 8.6 5.3 8.2 22.6 4.9 37.6 17.6 9.3 16.4 9.9 22.3 31.6 22.1 20.1 4.3 8.9 27.5 10.2 23.3 13.4 13.0 14.9 18.3 26.2 23.3 18.6 24.6 6.5 5.3 11.2 56.8 25.1 15.8 14.0 18.5 14.2 13.3 16.8 21.0 19.7 21.6 17.1 11.0 35.1 15.1 15.7 15.6 14.2 25.3 32.5 10.7 13.8 17.5 22.1 23.0 19.6 15.6 16.5 10.6 9.6 16.1 13.3 20.1 41.9 24.1 19.5 26.1 25.5 34.8 17.1 15.9 31.7 34.5 12.5 16.9 13.4 14.8 11.7 10.4 13.1 14.3 9.8 13.3 8.4 9.6 19.0 9.6 13.8 10.8 12.1 5.9 5.1 6.5 6.5 7.2 5.3 5.8 5.9 5.3 5.8 4.9 6.1 8.2 30.6 12.8 18.5 18.3 30.9 20.9 52.3 33.3 16.5 60.6 26.0 25.1 14.4 34.3 29.7 27.6 35.5 48.0 30.1 31.5 29.4 40.4 14.7 22.2 35.5 32.4 16.9 56.6 17.7 29.3 54.5 34.8 27.5 31.9 52.1 51.9 36.8 24.1 31.8 67.3 20.5 31.9 28.5 26.4 17.6 12.7 53.7 29.1 8.8 7.5 32.1 21.0 34.0 17.1 31.5 35.3 27.4 56.8 21.2 58.1 26.4 21.0 15.6 73.5 39.5 46.4 32.9 67.0 82.9 28.0 22.6 64.7 30.4 33.1 32.3 57.8 HNRNPAB "ABBP1, FLJ40338, HNRPAB" ENSG00000197451 "Heterogeneous nuclear ribonucleoprotein A/B" Q99729 5 178204533-178211163 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046688 Approved Enhanced Nucleoplasm NA NA 460000 "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046688: AB_10964924" "unprognostic (2.23e-1)" "unprognostic (6.21e-2)" "unprognostic (2.61e-2)" "unprognostic (1.96e-2)" "unprognostic (8.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (4.09e-2)" "unprognostic (6.17e-3)" "prognostic favorable (9.79e-4)" "unprognostic (9.12e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (1.35e-7)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" "unprognostic (3.53e-1)" "unprognostic (2.08e-1)" 86.7 103.2 33.2 92.5 34.9 139.7 63.9 35.6 37.0 66.0 37.3 144.7 98.2 75.5 43.8 122.0 64.4 51.1 83.1 32.4 39.1 91.9 88.3 69.1 95.7 36.9 35.4 56.7 55.4 76.2 46.2 64.0 36.9 59.8 119.0 27.1 68.1 54.0 119.0 115.4 88.9 74.4 35.5 79.9 85.5 38.2 36.9 117.0 52.0 58.7 102.7 122.3 72.7 38.5 347.4 282.5 424.1 414.7 153.8 134.6 613.2 378.5 174.3 296.9 317.2 525.4 251.8 555.2 340.3 204.7 361.1 223.2 373.1 516.7 363.8 865.9 439.5 349.8 223.7 325.1 153.7 446.1 285.6 134.0 239.2 267.3 266.8 122.3 270.3 218.4 290.1 245.7 302.0 934.2 542.6 429.7 389.5 354.0 401.7 436.3 255.6 329.8 254.2 364.8 389.5 302.4 295.2 407.9 278.8 264.0 244.7 270.7 244.0 359.7 305.2 256.2 527.8 285.4 360.2 649.3 145.2 488.2 298.8 3.2 4.4 15.7 5.1 7.0 5.7 5.9 4.1 6.0 4.4 5.2 3.9 4.7 0.8 5.8 7.5 10.9 4.8 2.2 33.2 34.9 35.6 37.0 32.4 39.1 36.9 35.4 36.9 35.5 36.9 38.5 124.7 32.1 41.0 4.6 115.4 281.6 212.1 42.7 243.0 26.5 129.6 141.3 45.9 41.5 42.7 49.7 18.8 106.3 148.5 251.2 50.9 118.9 9.3 112.4 225.6 107.1 119.2 273.2 3.5 151.7 208.9 110.1 167.7 124.7 44.5 102.0 53.6 101.2 101.0 16.8 4.3 219.0 48.8 67.0 129.9 11.1 74.0 109.9 67.6 8.4 56.2 34.7 76.2 3.5 6.1 204.2 138.2 88.0 179.6 275.0 90.5 116.8 25.8 28.3 78.9 149.7 173.6 81.6 122.4 362.5 339.8 114.4 129.7 238.1 247.9 235.5 HNRNPL HNRPL ENSG00000104824 "Heterogeneous nuclear ribonucleoprotein L" P14866 19 38836370-38852347 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016326, HPA051748, HPA052661" Supported Enhanced Nucleoplasm NA NA 420000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB016326: AB_627736, HPA051748: AB_2681588, HPA052661: AB_2681905" "unprognostic (5.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.27e-1)" "unprognostic (9.67e-3)" "unprognostic (8.99e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (3.25e-6)" "unprognostic (1.45e-1)" "unprognostic (8.85e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (1.96e-11)" "unprognostic (2.17e-2)" "unprognostic (4.23e-2)" "unprognostic (1.58e-2)" "unprognostic (4.39e-2)" 112.5 108.5 43.8 69.7 46.1 195.1 110.3 49.4 47.4 114.0 42.9 115.2 72.7 119.9 48.0 134.4 97.6 37.4 100.2 41.8 44.5 96.6 98.8 117.7 84.2 47.0 42.9 103.8 87.5 67.7 70.6 57.6 47.5 81.5 76.4 53.2 99.8 45.7 125.7 142.3 113.4 79.9 47.2 113.5 104.3 83.7 46.9 128.8 101.7 57.3 114.5 101.9 111.6 59.4 293.6 214.8 256.4 157.9 94.8 108.7 257.7 233.3 138.9 187.1 177.4 229.9 189.7 436.8 196.2 130.5 152.1 167.0 299.6 228.9 270.7 354.4 231.0 349.9 128.3 205.9 101.2 334.0 228.2 122.7 106.9 187.1 182.1 108.8 209.4 186.7 353.7 200.0 197.6 216.0 347.7 202.9 307.6 186.6 185.6 440.8 296.4 271.7 212.1 203.8 218.6 226.0 225.1 157.7 90.0 172.2 213.4 176.7 207.1 194.9 238.1 184.2 349.4 224.0 312.5 473.1 128.4 293.1 220.0 1.2 1.9 1.2 2.6 3.0 2.0 1.7 2.0 1.7 2.6 2.2 2.0 1.7 1.9 1.8 2.5 5.1 2.6 1.1 43.8 46.1 49.4 47.4 41.8 44.5 47.0 42.9 47.5 47.2 46.9 59.4 62.2 22.4 53.8 40.1 105.1 35.4 52.1 18.0 135.5 76.7 63.6 47.6 22.9 31.5 29.1 22.0 64.6 42.9 100.0 59.0 7.9 37.4 15.9 61.2 64.8 48.7 62.9 83.3 38.0 44.1 35.3 57.0 91.7 88.4 39.3 33.8 43.5 63.0 27.4 33.7 39.0 70.4 12.2 63.7 35.1 11.7 28.3 60.3 26.6 31.9 42.4 39.0 48.4 31.2 56.3 44.1 45.6 22.6 123.0 55.6 55.4 23.9 25.5 78.7 19.7 64.1 59.0 25.5 22.1 117.6 47.5 52.3 95.0 42.4 70.2 41.9 HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Mitochondria, Cytosol" "HPA046084: AB_10960895" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.18e-1)" "unprognostic (2.10e-3)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-2)" 16.0 16.4 16.3 12.5 20.7 51.7 14.7 19.3 21.3 16.2 12.9 16.1 15.5 18.2 13.9 10.2 16.7 14.1 12.8 28.6 8.3 11.1 10.8 16.4 12.5 5.9 8.1 16.9 15.9 16.8 9.2 13.1 7.2 13.9 11.8 26.6 12.8 15.0 13.8 11.4 12.7 12.8 7.8 12.0 15.7 22.6 9.3 31.0 17.7 11.9 9.6 15.2 12.8 15.8 36.7 16.9 48.2 28.4 22.9 21.6 30.1 33.8 27.5 28.8 24.1 19.0 20.7 0.5 29.5 30.4 30.9 23.0 30.7 25.4 29.6 54.6 26.8 26.7 32.3 48.6 21.6 49.9 26.4 16.9 19.6 24.0 26.5 28.5 30.6 23.9 45.9 79.7 34.3 17.2 54.9 27.2 48.4 35.2 30.6 10.6 33.9 18.1 25.0 47.2 32.9 36.9 29.8 25.8 26.0 26.7 21.8 21.6 32.0 21.5 32.1 23.8 28.1 43.4 46.9 0.3 18.5 12.2 26.8 10.6 6.3 9.7 10.3 3.2 17.9 0.4 24.2 18.9 12.0 1.9 7.2 4.6 4.2 6.8 1.2 0.2 38.5 5.8 16.3 20.7 19.3 21.3 28.6 8.3 5.9 8.1 7.2 7.8 9.3 15.8 17.0 19.2 23.4 26.8 5.5 28.7 35.2 16.5 33.0 13.3 18.0 15.2 18.8 8.6 18.8 27.6 8.4 26.2 6.4 13.9 19.6 22.4 155.6 18.1 18.8 20.1 14.4 22.5 68.6 24.3 28.9 26.0 32.1 11.6 9.5 26.3 22.5 7.4 24.4 6.7 40.1 15.4 6.1 15.0 90.2 48.7 27.7 23.1 39.2 37.5 24.5 22.3 2.1 48.7 28.4 21.2 14.2 52.3 23.0 23.6 16.6 18.6 14.5 11.7 39.5 22.6 28.4 91.1 28.8 19.4 21.3 22.2 48.0 22.3 18.8 21.4 HNRNPM "CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1" ENSG00000099783 "Heterogeneous nuclear ribonucleoprotein M" P52272 19 8444767-8489114 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016113, HPA024344" Supported Enhanced Nucleoplasm NA NA 440000 "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB016113: AB_627739, HPA024344: AB_1850879" "unprognostic (2.12e-1)" "unprognostic (8.59e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (1.80e-6)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (6.91e-3)" "unprognostic (4.70e-3)" "unprognostic (7.34e-2)" "unprognostic (3.62e-2)" "unprognostic (1.22e-3)" "unprognostic (1.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.73e-1)" 97.2 83.9 55.6 126.3 63.0 230.9 94.4 66.0 63.8 104.4 61.4 108.3 98.4 113.8 57.1 126.4 92.5 54.4 89.1 51.6 61.0 92.4 89.4 90.6 141.3 60.7 59.1 121.9 84.1 90.5 71.5 87.5 60.8 76.6 91.9 127.7 93.0 75.4 148.6 106.5 100.8 88.0 57.2 110.5 90.9 78.1 59.8 166.3 93.2 62.1 156.0 93.2 101.5 69.3 477.5 315.7 580.8 236.3 131.4 145.2 373.7 279.3 208.5 340.3 256.9 452.4 141.4 697.4 363.4 254.3 242.4 286.3 603.3 349.4 425.1 437.5 501.0 620.1 312.2 439.8 136.3 640.0 317.4 150.5 173.4 289.2 119.9 100.0 309.7 256.3 632.3 193.6 273.3 324.3 617.2 556.8 505.1 258.2 381.1 687.8 508.1 330.5 179.6 452.9 320.7 356.8 469.5 250.4 278.8 276.8 299.0 378.4 362.9 294.5 357.4 313.6 529.2 285.4 560.8 791.4 221.7 511.4 329.1 21.3 78.4 48.0 91.2 93.4 91.7 69.6 79.0 91.6 86.6 61.4 84.3 83.0 20.0 86.0 71.8 86.3 87.6 94.5 55.6 63.0 66.0 63.8 51.6 61.0 60.7 59.1 60.8 57.2 59.8 69.3 157.1 128.2 189.0 48.6 154.1 166.3 204.8 240.8 105.9 199.6 143.8 125.1 92.1 118.7 240.8 117.7 70.9 272.8 170.3 95.5 97.8 237.4 13.2 150.6 194.7 164.3 190.4 211.5 43.3 273.1 304.4 141.7 76.0 190.2 267.4 136.3 111.4 148.5 174.4 138.0 46.5 154.6 138.4 127.2 139.8 18.3 113.4 137.7 110.3 59.0 212.5 186.1 219.4 60.8 79.8 202.2 102.9 142.1 118.7 92.7 77.8 106.0 193.1 213.6 210.4 194.1 231.2 182.3 150.6 106.3 137.0 262.4 168.7 125.4 183.3 131.3 HNRNPUL1 "E1B-AP5, E1BAP5, FLJ12944, HNRPUL1" ENSG00000105323 "Heterogeneous nuclear ribonucleoprotein U like 1" Q9BUJ2 19 41262496-41307787 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046290, CAB046477, HPA049475" Enhanced Enhanced Nucleoplasm NA NA 26000 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB046477: AB_2120664, HPA046290: AB_2679616, HPA049475: AB_2680783" "unprognostic (5.52e-2)" "unprognostic (6.37e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.39e-1)" "unprognostic (4.29e-2)" "unprognostic (3.45e-3)" "unprognostic (1.94e-1)" "unprognostic (6.08e-2)" "unprognostic (2.86e-1)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (5.78e-2)" "unprognostic (2.32e-1)" "unprognostic (1.66e-1)" "unprognostic (8.05e-2)" "unprognostic (2.39e-1)" 85.7 65.9 53.2 89.1 62.4 176.2 75.0 64.3 63.8 78.0 58.9 85.7 81.3 85.0 49.1 81.4 82.8 58.0 75.7 52.9 58.9 48.3 52.5 75.0 102.4 63.9 56.3 116.3 71.7 64.7 58.3 48.8 60.6 59.6 73.1 91.2 84.7 66.7 92.7 93.2 78.7 79.0 53.1 86.4 73.5 79.8 56.1 140.0 69.9 75.6 109.6 75.2 72.1 66.0 284.3 371.2 216.5 200.4 104.3 124.0 82.2 163.1 194.1 207.1 187.8 218.7 213.2 250.1 112.3 206.4 116.8 91.2 208.1 191.3 234.6 248.5 172.9 272.9 168.8 170.4 121.0 259.5 244.3 132.9 116.8 185.8 171.6 186.5 195.7 187.1 203.1 233.8 185.9 217.0 341.0 151.8 165.0 270.8 126.7 219.0 171.6 142.3 149.0 298.8 171.2 154.2 363.3 212.6 95.4 147.7 163.7 290.2 188.4 231.6 218.6 105.4 318.3 264.3 184.5 238.4 147.5 210.8 311.6 13.2 6.2 11.0 11.9 6.7 18.1 8.8 14.4 12.4 7.3 9.0 9.9 7.9 13.5 12.6 7.9 13.7 10.9 5.7 53.2 62.4 64.3 63.8 52.9 58.9 63.9 56.3 60.6 53.1 56.1 66.0 57.0 80.1 69.6 14.7 105.4 56.2 42.9 35.9 71.7 63.2 69.0 58.5 64.1 52.9 36.1 31.3 73.0 50.1 151.9 51.4 45.0 65.1 51.6 52.7 76.8 57.7 76.7 129.4 13.9 62.2 58.8 67.7 55.5 54.2 58.9 78.8 60.3 43.0 63.6 48.8 16.2 66.4 30.5 102.4 76.5 73.9 86.3 92.3 35.6 16.9 81.1 70.8 93.7 21.6 22.2 68.6 39.4 71.5 152.2 48.6 49.5 29.5 49.9 97.3 78.9 74.7 70.3 113.6 108.9 99.1 60.2 53.4 134.2 60.3 73.6 43.6 HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 30000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA028215: AB_10601021, HPA054295: AB_2682440" "unprognostic (3.90e-3)" "unprognostic (6.83e-2)" "unprognostic (7.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.65e-1)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" 87.9 78.9 62.2 76.2 75.1 141.7 80.1 69.6 76.5 143.6 62.1 107.9 71.3 116.5 63.0 94.8 96.7 75.3 75.7 64.5 66.6 83.5 66.5 84.1 91.4 68.1 64.4 135.6 74.4 98.1 60.9 85.9 67.5 81.3 88.2 96.4 83.0 74.3 113.9 86.9 93.8 100.3 61.3 89.2 83.1 54.5 68.7 134.5 106.3 78.7 90.3 93.9 114.2 107.6 207.3 106.1 261.6 157.5 152.3 172.8 157.3 230.2 182.4 156.7 163.1 97.6 232.0 208.2 113.4 176.6 108.4 171.9 136.7 125.5 199.8 306.5 124.7 296.2 230.5 85.4 98.1 209.7 181.7 135.1 90.6 159.0 208.5 193.0 160.5 245.1 169.9 251.8 180.1 64.2 323.5 93.0 69.3 152.6 126.3 250.4 255.0 219.2 113.6 66.6 175.0 180.0 279.8 112.9 181.2 132.9 117.3 138.7 196.4 176.2 164.2 180.7 139.2 144.0 194.2 246.7 150.2 213.0 204.0 102.4 55.3 202.6 57.1 45.0 59.7 70.8 61.9 62.1 52.2 58.4 80.4 54.5 66.1 63.3 54.9 59.5 71.6 49.0 62.2 75.1 69.6 76.5 64.5 66.6 68.1 64.4 67.5 61.3 68.7 107.6 129.4 150.6 156.2 96.9 112.1 130.4 137.4 81.6 159.9 117.8 116.6 108.7 161.4 94.4 94.5 104.8 54.2 87.6 144.7 105.6 154.6 87.0 40.8 85.3 184.6 136.8 103.7 214.6 98.3 93.4 70.7 161.9 98.8 128.2 137.8 131.8 129.2 101.0 72.6 80.8 93.7 113.4 83.4 100.7 104.1 22.3 172.7 116.9 113.8 130.2 111.2 119.5 127.7 142.7 189.9 113.0 90.1 162.5 162.0 124.6 91.7 110.7 54.6 97.6 157.8 145.2 148.3 141.3 110.1 201.8 134.5 92.9 151.9 116.2 115.3 118.4 HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0;heart muscle: 26.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 26.2;Excitatory neurons: 62.2;Inhibitory neurons: 19.1;Kupffer cells: 29.4;Macrophages: 36.2;monocytes: 24.3;Smooth muscle cells: 33.6" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 134.4;neutrophil: 161.7" "Group enriched" "Detected in many" 5 "granulocytes: 161.7;monocytes: 51.6" "Group enriched" "Detected in some" 4 "RPMI-8226: 65.6;SK-MEL-30: 19.2;THP-1: 18.0;U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" 7.6 1.5 4.5 12.0 14.4 37.0 3.0 1.1 9.6 5.1 0.5 1.4 6.2 2.2 0.9 1.4 2.9 2.5 26.3 5.3 1.4 2.3 1.0 7.2 3.8 1.2 1.6 1.1 1.5 1.3 0.8 10.2 1.1 4.7 1.1 0.3 1.4 4.6 0.8 2.2 6.4 3.6 1.7 18.0 19.5 0.5 3.9 8.5 1.5 1.5 3.1 4.1 2.0 5.1 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 5.0 2.9 0.0 0.0 7.1 0.0 65.6 0.0 0.3 0.5 0.0 0.0 0.0 19.2 1.7 0.1 18.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.6 4.3 134.4 45.8 52.8 0.2 44.9 0.3 0.0 3.8 1.0 23.5 0.1 7.9 4.8 161.7 2.1 51.6 18.3 3.3 15.3 4.5 14.4 1.1 9.6 5.3 1.4 1.2 1.6 1.1 1.7 3.9 5.1 1.1 0.0 2.5 1.0 1.0 0.8 0.1 0.0 0.6 9.3 3.7 0.9 26.2 0.0 2.5 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.6 0.1 0.8 1.9 0.0 3.0 62.2 2.4 0.2 3.3 7.1 0.1 2.5 3.0 0.0 0.2 11.8 1.7 19.1 0.6 0.0 29.4 8.5 1.0 0.0 36.2 0.0 10.3 24.3 0.1 0.0 1.5 1.7 0.3 0.0 0.4 0.3 0.2 0.6 0.3 0.7 0.2 0.0 0.1 33.6 0.2 0.9 0.1 0.3 0.0 4.7 0.1 0.5 0.0 HSPA14 "HSP70-4, HSP70L1" ENSG00000187522 "Heat shock protein family A (Hsp70) member 14" Q0VDF9 10 14838306-14871741 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 223.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046180 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA046180: AB_2679571" "unprognostic (5.84e-3)" "unprognostic (5.85e-3)" "unprognostic (5.73e-2)" "unprognostic (6.40e-3)" "unprognostic (7.98e-3)" "prognostic favorable (5.73e-4)" "prognostic unfavorable (3.70e-8)" "unprognostic (2.20e-1)" "unprognostic (9.60e-2)" "prognostic favorable (9.16e-4)" "unprognostic (1.34e-1)" "unprognostic (1.17e-3)" "prognostic unfavorable (1.09e-5)" "unprognostic (7.27e-2)" "unprognostic (2.27e-1)" "unprognostic (5.42e-2)" "unprognostic (2.90e-1)" 8.9 9.2 9.2 14.7 9.5 42.8 13.3 13.5 12.4 8.5 7.8 14.7 13.1 9.2 11.1 11.0 7.1 8.9 11.4 10.0 9.5 10.2 11.8 8.8 19.4 8.3 8.2 7.9 11.5 8.2 8.8 10.1 8.6 8.8 17.8 10.3 10.1 8.9 21.4 13.3 12.5 9.7 8.6 12.0 9.4 30.9 9.1 18.6 10.3 16.6 19.1 13.0 8.0 10.2 54.0 38.9 33.7 30.7 15.7 21.7 43.6 27.8 14.6 47.5 37.9 52.1 38.9 66.8 21.6 25.7 23.5 43.1 55.3 32.8 49.7 28.2 56.0 62.1 33.0 30.4 13.4 43.6 39.9 15.9 15.0 38.9 11.4 11.8 24.3 53.8 54.3 53.6 35.4 37.3 65.7 30.4 34.9 55.2 20.7 50.3 43.8 53.9 24.7 27.2 19.1 23.5 31.3 43.1 35.8 32.0 49.0 57.6 13.6 19.8 27.7 77.8 45.1 36.6 85.4 67.8 39.6 56.3 11.4 15.8 12.3 13.3 13.7 18.0 14.9 15.1 14.0 17.2 13.4 14.5 11.7 14.6 6.1 17.8 15.8 14.7 20.3 10.7 9.2 9.5 13.5 12.4 10.0 9.5 8.3 8.2 8.6 8.6 9.1 10.2 8.2 6.4 3.3 7.2 18.7 26.3 20.5 37.9 30.7 16.6 7.8 5.8 19.3 14.3 21.2 3.7 6.2 36.2 17.5 16.2 1.9 4.2 53.9 6.7 8.7 12.1 6.0 20.4 21.8 3.9 65.6 16.2 18.3 8.9 10.2 7.4 11.7 12.6 22.8 6.7 19.5 17.0 26.4 11.6 20.3 14.6 14.0 12.1 14.2 10.3 9.0 17.6 23.7 14.6 15.9 4.7 19.9 12.4 33.3 24.4 15.2 2.0 12.5 13.7 13.1 23.3 33.1 223.8 71.4 25.7 26.1 48.7 21.5 8.0 21.2 22.2 IER5 ENSG00000162783 "Immediate early response 5" Q5VY09 1 181088700-181092900 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 282.8;Macrophages: 276.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029894 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA029894: AB_10601433" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "unprognostic (2.55e-1)" "prognostic favorable (2.42e-7)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.81e-3)" "unprognostic (8.37e-2)" "unprognostic (1.46e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (1.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" 12.8 6.3 9.5 11.2 10.2 49.5 8.4 10.1 19.3 10.2 11.2 10.6 5.6 14.8 2.5 26.5 15.2 6.1 27.8 10.7 9.7 5.8 6.7 23.2 9.4 10.0 9.2 3.3 5.2 1.8 5.2 11.0 9.1 5.6 5.6 1.1 6.8 3.7 33.4 22.1 13.3 8.3 9.8 32.7 9.0 5.4 10.3 8.7 5.0 16.5 10.8 10.9 13.3 12.8 25.3 21.8 11.7 10.3 15.9 21.9 31.3 43.6 45.9 24.1 21.4 6.1 13.8 8.3 18.9 16.9 16.9 45.5 3.8 29.7 15.6 47.6 18.7 7.4 11.5 4.1 24.9 8.6 23.1 15.7 29.5 28.0 18.7 18.3 16.6 6.9 31.0 36.5 43.3 11.5 8.6 13.8 12.2 9.5 10.8 9.8 20.4 31.6 8.8 13.7 16.9 18.2 22.1 21.3 51.7 14.2 17.0 7.5 25.3 17.3 30.5 19.9 26.8 23.9 9.1 6.5 13.5 9.0 4.9 3.6 1.4 2.7 1.0 5.5 1.2 4.0 0.8 1.4 1.1 3.0 0.1 0.5 1.2 1.1 5.3 0.2 1.3 0.7 9.5 10.2 10.1 19.3 10.7 9.7 10.0 9.2 9.1 9.8 10.3 12.8 156.4 22.4 66.7 3.6 124.8 69.8 163.7 24.2 53.5 24.2 198.1 197.7 110.9 21.5 25.9 9.2 37.5 10.9 131.1 94.2 0.0 10.6 5.1 66.7 83.0 87.2 56.4 32.0 8.7 6.9 56.4 74.7 50.0 67.3 36.1 35.0 41.4 5.6 50.9 8.4 2.8 110.6 6.1 149.5 282.8 11.9 12.2 276.4 46.2 11.2 56.1 17.8 17.5 0.5 1.3 21.9 54.8 9.4 61.5 94.9 35.0 1.5 27.4 21.3 0.0 177.9 102.8 3.6 5.4 115.9 59.7 34.2 151.3 15.5 62.0 146.8 IK "RED, RER" ENSG00000113141 "IK cytokine" Q13123 5 140647058-140662480 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 438.7;Endometrial ciliated cells: 510.8;Respiratory ciliated cells: 732.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048798 Supported Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA048798: AB_2680525" "unprognostic (9.90e-2)" "prognostic favorable (1.29e-4)" "unprognostic (6.99e-2)" "unprognostic (1.49e-2)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (2.32e-7)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (4.37e-2)" "unprognostic (8.45e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-3)" "unprognostic (3.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.26e-2)" "unprognostic (2.83e-1)" 73.9 64.0 53.4 68.7 56.6 135.4 66.9 64.4 70.8 70.0 62.3 76.1 55.4 73.9 74.4 77.0 143.5 53.4 74.2 54.2 68.6 67.0 68.6 69.5 89.9 60.6 60.6 78.8 48.3 74.3 55.8 64.9 59.9 60.3 70.3 90.4 65.2 66.2 136.5 73.4 67.9 64.6 57.0 71.6 60.5 107.7 57.6 114.0 72.6 83.0 96.0 69.6 68.1 62.3 119.1 132.5 114.4 163.2 125.7 106.4 133.4 139.0 146.7 151.6 153.2 184.1 133.4 138.9 167.4 145.4 172.3 120.9 168.2 190.1 175.4 198.1 136.6 130.4 213.2 117.8 129.6 214.6 136.9 117.2 124.4 151.5 136.8 112.0 132.7 114.9 144.3 121.1 137.3 110.0 184.1 216.8 74.5 100.3 134.2 145.5 160.7 141.4 117.7 109.2 103.6 112.3 171.5 155.6 172.9 97.9 181.3 171.8 141.2 126.2 87.9 106.2 167.8 181.8 294.1 188.4 141.8 162.4 94.5 353.1 136.5 240.3 188.3 157.1 168.9 197.4 202.7 194.3 139.0 191.5 212.7 199.1 229.4 198.8 193.0 131.2 284.4 247.0 53.4 56.6 64.4 70.8 54.2 68.6 60.6 60.6 59.9 57.0 57.6 62.3 110.7 163.5 134.9 10.1 102.8 46.1 86.4 127.5 61.5 75.3 40.0 57.7 126.7 80.1 177.1 86.5 29.2 115.2 139.9 69.2 121.3 106.4 438.7 510.8 124.9 91.4 34.1 137.6 7.6 99.6 99.6 82.6 50.0 107.2 132.2 68.0 54.3 74.7 70.6 53.8 8.2 66.4 97.6 56.8 58.8 55.0 98.2 80.2 56.9 8.4 107.4 116.1 151.4 8.5 7.4 110.1 67.3 83.8 76.9 50.5 80.4 120.8 732.0 97.3 72.3 96.0 115.7 311.3 145.0 65.3 45.5 132.8 128.5 93.0 65.5 66.9 ILF3 "DRBP76, MPHOSPH4, MPP4, MPP4110, NF110, NF110b, NF90, NF90a, NF90c, NF90ctv, NFAR-1, NFAR-2, NFAR110, NFAR90, TCP110" ENSG00000129351 "Interleukin enhancer binding factor 3" Q12906 19 10654261-10692417 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001897 Supported Enhanced Nucleoplasm,Nucleoli,Mitochondria No No 1600000 "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Mitochondria" "HPA001897: AB_1078703" "unprognostic (2.39e-1)" "unprognostic (9.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (5.55e-3)" "unprognostic (1.11e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.45e-2)" "unprognostic (1.04e-1)" "unprognostic (4.38e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (7.57e-3)" "unprognostic (7.61e-2)" "unprognostic (1.03e-1)" "unprognostic (6.20e-2)" 49.2 58.5 31.6 79.4 31.5 179.5 49.8 44.2 37.5 60.8 38.5 56.0 52.0 64.5 40.9 60.4 61.1 31.9 49.0 31.4 37.9 43.1 32.1 50.5 82.9 30.6 32.8 76.5 52.6 55.5 53.8 47.8 29.7 52.4 44.8 69.5 54.0 48.8 83.6 58.7 56.1 49.8 29.4 61.7 47.8 78.9 35.4 97.3 61.6 58.2 72.3 56.1 52.1 42.8 285.9 226.7 359.5 330.9 76.5 104.0 208.9 178.1 149.6 291.8 226.5 261.8 160.8 353.2 172.1 160.8 178.0 248.9 392.5 240.7 260.9 227.2 349.5 459.3 206.9 247.5 109.2 334.8 219.5 99.0 105.0 232.1 257.4 111.1 253.1 201.7 400.0 269.4 172.3 233.8 558.1 534.0 433.3 149.2 246.2 405.2 342.2 244.2 116.3 297.1 395.1 286.7 229.0 179.4 131.6 161.6 152.2 212.0 205.2 237.6 224.2 249.3 356.5 228.9 339.7 431.4 132.8 351.6 262.2 20.2 18.1 10.2 24.4 14.1 20.6 19.3 20.2 22.3 22.8 22.9 19.5 20.2 2.7 21.3 21.2 25.1 20.6 11.8 31.6 31.5 44.2 37.5 31.4 37.9 30.6 32.8 29.7 29.4 35.4 42.8 63.6 99.3 133.9 34.3 106.2 86.2 110.0 64.2 104.7 95.4 77.5 64.3 69.7 60.1 98.8 42.3 85.5 90.0 100.0 78.4 27.4 89.0 21.2 89.8 105.7 77.4 114.0 124.3 24.4 80.4 111.1 94.8 101.9 121.4 96.8 145.9 36.8 47.9 71.4 94.2 34.0 85.6 50.8 55.0 68.3 21.0 76.4 75.8 39.2 24.4 66.0 69.2 92.7 31.7 28.9 88.2 55.6 62.4 124.9 144.6 38.8 47.2 82.9 103.6 32.9 100.3 80.1 137.2 120.6 113.8 77.0 70.9 103.5 140.8 111.7 94.9 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81656914-81686331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved NA No 310000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 12.8 11.3 12.7 12.7 13.3 27.0 10.2 11.8 15.8 8.9 14.8 26.9 23.5 10.4 11.7 20.7 11.8 11.8 25.8 14.6 12.6 16.4 31.3 10.2 17.6 10.9 13.4 13.5 8.6 15.5 10.1 8.2 13.0 11.0 28.4 18.2 8.3 8.1 14.1 5.1 23.2 18.0 12.4 11.2 14.7 38.2 12.1 19.6 21.8 29.0 16.3 14.0 10.5 15.1 12.5 34.6 23.3 17.2 14.0 21.9 9.8 35.7 26.5 31.3 36.7 16.3 20.1 47.2 27.5 26.2 45.6 9.4 27.1 12.0 41.3 50.7 26.5 35.7 19.2 20.8 23.8 36.7 35.0 20.3 17.6 24.9 48.2 30.2 35.2 35.6 32.8 38.7 30.6 8.7 46.1 18.4 10.1 32.2 37.2 21.2 16.9 19.2 31.7 43.5 9.3 38.7 23.9 6.2 41.3 39.6 20.4 27.4 26.4 24.9 32.8 19.8 44.1 45.2 58.5 67.4 29.4 20.7 35.9 50.5 6.6 29.4 13.6 10.3 16.8 20.3 13.5 14.9 7.5 13.7 14.0 16.8 11.2 20.5 11.8 12.0 19.6 9.5 12.7 13.3 11.8 15.8 14.6 12.6 10.9 13.4 13.0 12.4 12.1 15.1 22.2 16.0 12.7 15.3 25.7 13.8 16.9 16.8 28.5 15.8 8.5 6.9 38.3 21.5 17.3 9.2 14.6 9.7 29.4 54.4 31.3 16.2 4.0 23.2 19.7 16.5 21.5 11.6 19.4 20.3 11.0 16.1 12.2 17.3 33.0 11.5 13.9 32.9 14.3 25.2 12.5 19.8 18.3 16.2 13.1 8.2 15.5 16.4 12.4 12.2 21.9 23.4 13.4 14.1 14.0 19.0 62.3 15.1 18.1 14.4 30.4 30.7 25.1 15.9 13.1 15.5 17.0 78.4 19.2 26.9 8.7 3.0 26.2 18.7 22.3 21.3 ING3 "Eaf4, FLJ20089, MEAF4, p47ING3" ENSG00000071243 "Inhibitor of growth family member 3" Q9NXR8 7 120950763-120977216 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 80.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004762, HPA067388, HPA067575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA004762: , HPA067388: AB_2685831, HPA067575: AB_2685863" "unprognostic (1.35e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-1)" "unprognostic (1.78e-1)" "unprognostic (3.03e-1)" "unprognostic (1.39e-2)" "unprognostic (4.26e-2)" "unprognostic (7.09e-3)" "unprognostic (4.07e-2)" "unprognostic (5.18e-2)" "unprognostic (8.04e-3)" "unprognostic (2.86e-1)" "unprognostic (6.90e-2)" "unprognostic (3.96e-2)" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (5.64e-2)" 9.3 7.7 3.8 9.9 4.5 80.5 10.1 11.3 5.5 8.3 3.3 9.1 8.2 10.8 10.5 7.4 9.7 8.5 8.5 3.5 4.5 9.7 9.2 10.9 14.9 4.2 4.7 8.9 8.5 7.7 6.0 15.1 4.7 8.0 11.8 7.6 8.6 7.7 4.7 4.6 7.6 13.0 4.8 15.5 9.7 8.1 4.2 18.6 11.5 8.4 13.5 8.5 5.0 5.7 19.3 5.6 24.8 14.0 9.2 7.3 8.3 12.9 10.1 18.1 21.1 7.3 21.6 31.3 5.7 11.3 19.0 9.2 24.1 9.9 20.7 22.1 42.2 22.5 21.2 4.3 12.6 43.8 25.5 5.4 5.0 16.0 11.3 8.7 28.7 19.1 51.0 48.4 17.5 6.7 36.0 26.0 29.9 10.9 10.4 17.6 17.7 25.7 18.4 19.4 22.4 24.1 13.3 26.9 14.0 15.3 6.1 17.0 10.4 18.5 6.8 40.0 23.7 22.2 15.1 46.0 9.3 28.9 15.6 44.0 28.0 26.4 20.1 30.8 19.9 21.7 20.3 18.7 23.4 24.3 20.4 18.6 50.7 30.6 32.3 17.7 27.1 14.8 3.8 4.5 11.3 5.5 3.5 4.5 4.2 4.7 4.7 4.8 4.2 5.7 27.1 19.2 18.4 24.5 37.7 7.6 20.4 17.6 9.1 23.3 16.3 14.4 14.2 11.5 14.0 7.3 4.2 38.8 31.7 19.6 21.5 12.6 7.2 21.5 20.1 24.7 12.0 27.0 14.5 18.0 22.0 19.5 16.8 28.3 33.7 21.8 21.4 14.3 17.9 26.9 21.5 18.7 22.4 35.8 16.6 4.3 13.7 23.4 16.0 18.7 24.3 17.6 27.8 22.6 24.3 15.5 17.7 9.8 26.8 14.0 17.7 12.8 13.5 19.8 19.7 26.9 25.9 16.6 15.3 12.0 11.2 45.7 28.6 25.7 15.4 18.7 INO80 "hINO80, INO80A, INOC1, KIAA1259" ENSG00000128908 "INO80 complex ATPase subunit" Q9ULG1 15 40978880-41116280 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Actin-binding, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041484, HPA048601" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" Cytosol "HPA041484: AB_2677506, HPA048601: " "unprognostic (5.39e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (3.92e-2)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.93e-1)" "unprognostic (6.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.69e-2)" "prognostic favorable (6.30e-4)" "unprognostic (1.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-2)" 9.3 6.5 5.4 7.3 5.7 15.7 8.8 10.1 5.9 8.3 5.3 9.3 7.3 8.9 4.7 9.6 7.7 5.7 6.9 5.3 5.2 7.9 7.8 9.4 9.7 5.9 5.2 9.1 6.9 10.0 5.5 6.8 5.6 7.9 8.6 5.7 7.3 6.6 15.7 10.9 8.7 8.2 5.0 8.9 7.9 7.0 5.8 10.8 8.5 9.6 10.4 9.1 8.5 7.5 13.1 12.9 10.6 10.7 16.5 13.8 11.4 12.2 18.8 17.3 15.0 14.8 10.4 14.0 8.8 17.6 21.6 24.3 19.5 20.7 19.0 17.5 10.0 18.9 17.7 11.8 15.2 17.9 16.2 13.5 18.4 13.8 36.9 11.1 16.8 14.5 20.5 11.6 12.3 10.6 13.2 11.2 11.3 20.6 13.5 19.1 11.2 11.0 12.7 26.1 14.5 9.6 9.6 18.5 7.3 10.4 10.5 19.9 19.2 14.3 11.1 17.3 19.0 12.4 9.6 22.2 16.1 24.7 11.7 0.3 1.0 0.2 0.8 0.5 0.9 1.3 0.8 0.8 0.7 1.1 1.0 1.1 0.3 2.1 0.2 0.6 0.7 0.4 5.4 5.7 10.1 5.9 5.3 5.2 5.9 5.2 5.6 5.0 5.8 7.5 23.7 9.6 25.7 27.4 27.6 8.5 16.2 7.5 23.3 30.4 18.1 15.9 25.1 14.3 16.4 16.5 22.9 13.5 25.4 17.3 7.9 17.6 2.2 17.2 21.5 17.6 13.1 23.8 54.1 13.3 12.0 16.0 32.6 28.9 15.8 18.4 13.2 10.0 9.8 26.9 47.5 11.8 2.0 14.4 6.8 3.3 14.6 18.6 7.2 25.3 20.8 12.9 19.6 43.2 53.3 15.2 16.1 15.8 19.8 21.7 9.5 11.3 16.3 33.0 6.6 28.1 21.3 19.2 24.7 28.2 12.8 19.2 25.8 25.1 13.9 15.1 INO80D FLJ20309 ENSG00000114933 "INO80 complex subunit D" Q53TQ3 2 205993721-206086303 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.9" "Cell type enhanced" "Detected in all" "Astrocytes: 158.7;Excitatory neurons: 127.7;Inhibitory neurons: 129.0;Oligodendrocytes: 188.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043976 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA043976: AB_10960835" "unprognostic (6.79e-2)" "unprognostic (9.77e-2)" "unprognostic (1.34e-1)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "prognostic favorable (5.53e-4)" "unprognostic (4.83e-3)" "unprognostic (3.00e-1)" "unprognostic (8.10e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" "unprognostic (1.39e-2)" "unprognostic (4.05e-3)" "unprognostic (1.30e-1)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (3.03e-2)" 4.6 3.0 0.7 2.3 1.1 17.9 4.3 5.3 1.4 4.3 1.0 3.9 3.4 4.0 1.4 4.4 3.9 3.0 3.6 0.5 0.6 3.0 3.7 4.1 4.4 1.4 0.5 5.1 4.1 1.4 4.0 2.5 0.8 3.4 1.4 5.1 4.2 0.9 5.7 6.1 4.7 1.0 0.0 3.9 3.8 5.6 1.1 1.7 5.2 1.7 1.7 3.6 4.5 3.0 2.4 1.8 4.5 3.6 1.3 1.6 3.3 1.8 0.9 1.3 1.0 3.6 4.7 2.4 2.9 1.1 4.5 3.2 1.7 1.2 1.5 2.1 3.3 5.2 4.2 4.4 0.8 4.5 3.3 1.0 1.6 1.6 2.1 3.5 1.7 2.9 5.1 5.6 1.4 3.2 2.5 14.8 6.0 1.4 2.6 3.1 2.8 2.6 1.3 4.1 4.1 3.9 3.3 2.1 3.5 3.6 2.9 4.4 4.7 3.7 3.6 1.6 2.2 7.0 5.7 6.1 2.9 3.9 2.8 4.1 2.2 2.0 3.0 1.2 2.5 4.1 2.2 1.4 1.6 5.2 2.5 1.9 5.1 2.0 3.4 4.5 2.6 0.9 0.7 1.1 5.3 1.4 0.5 0.6 1.4 0.5 0.8 0.0 1.1 3.0 31.5 22.4 34.7 158.7 35.5 30.8 18.2 9.8 25.6 39.5 19.9 13.8 17.5 31.5 18.6 18.4 39.6 8.4 43.0 27.3 5.9 13.5 3.7 25.3 31.4 27.8 25.2 29.9 127.7 13.1 5.9 29.4 26.5 41.2 32.4 24.1 17.2 16.3 11.7 11.8 129.0 20.3 4.1 21.7 28.9 5.4 20.2 23.1 17.8 117.1 25.9 16.8 26.8 126.2 188.3 17.8 19.9 15.4 33.2 26.1 24.3 12.8 16.2 39.9 13.1 55.6 29.3 11.3 5.7 31.2 29.1 15.5 33.6 16.4 17.8 25.7 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 ISY1 "fSAP33, KIAA1160" ENSG00000240682 "ISY1 splicing factor homolog" Q9ULR0 3 129127415-129161063 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006312, HPA016995" Supported Enhanced "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA006312: AB_1079734, HPA016995: AB_1852387" "unprognostic (2.20e-2)" "prognostic favorable (2.46e-5)" "unprognostic (1.46e-2)" "unprognostic (1.84e-3)" "unprognostic (2.19e-1)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.25e-4)" "unprognostic (4.08e-1)" "unprognostic (5.94e-2)" "unprognostic (7.38e-2)" "unprognostic (1.71e-1)" "unprognostic (7.34e-2)" "unprognostic (2.23e-3)" "unprognostic (2.49e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.54e-2)" 18.7 13.7 9.1 19.0 9.0 51.6 17.0 9.8 9.6 20.2 7.5 21.6 15.4 19.5 15.1 22.2 15.5 17.4 21.4 8.8 9.1 15.0 10.8 14.1 32.0 9.2 9.3 19.7 15.8 11.2 8.8 22.1 8.9 13.3 16.9 10.4 15.0 12.3 34.9 20.3 16.2 20.3 8.2 18.2 14.9 12.4 8.8 22.7 14.9 21.3 30.1 18.3 19.4 8.9 53.7 20.5 29.6 41.6 35.1 36.4 34.5 39.3 35.0 46.1 44.2 40.6 39.3 67.3 41.3 32.6 40.0 44.8 56.3 31.8 64.9 65.0 26.5 78.0 35.2 32.8 32.7 121.2 53.4 22.9 21.7 40.6 62.3 28.7 37.7 43.2 57.1 33.5 25.2 54.2 73.8 67.1 32.3 55.9 31.3 64.9 67.3 47.5 17.3 33.5 46.8 35.3 72.7 15.7 41.9 16.0 30.3 99.1 45.2 33.5 33.4 49.8 41.6 40.1 26.1 131.9 30.8 69.4 39.0 79.8 57.6 94.2 54.8 56.4 61.4 56.1 55.8 58.7 62.8 50.7 61.0 55.0 90.7 84.8 51.2 54.5 73.5 56.5 9.1 9.0 9.8 9.6 8.8 9.1 9.2 9.3 8.9 8.2 8.8 8.9 26.5 25.6 23.4 0.0 27.4 27.4 16.5 21.3 20.5 19.7 17.0 15.6 19.7 21.5 21.8 9.2 22.9 44.1 38.5 15.8 23.5 26.7 2.8 11.9 23.0 25.3 9.0 29.0 0.0 28.0 41.2 21.8 12.8 21.0 45.6 25.8 26.0 12.3 34.8 20.2 0.0 16.7 16.2 21.1 25.6 1.8 16.1 23.9 10.6 0.0 43.7 20.7 46.4 0.0 0.0 24.4 15.3 16.1 24.1 17.4 18.8 23.2 14.8 19.0 19.7 18.8 20.9 57.4 42.6 20.0 35.8 45.8 32.9 18.7 20.5 16.9 ITGAE "CD103, HUMINAE" ENSG00000083457 "Integrin subunit alpha E" P38570 17 3714628-3801188 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;intestine: 5.9;lung: 6.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 6 "T-cells: 3.7" "Cell line enriched" "Detected in single" 22 "MOLT-4: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036313, HPA052147" Enhanced NA NA 38000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA036313: AB_10795355, HPA052147: " "unprognostic (9.81e-2)" "unprognostic (1.78e-3)" "unprognostic (7.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (2.17e-1)" "unprognostic (1.45e-2)" "unprognostic (2.91e-1)" "unprognostic (8.02e-2)" "unprognostic (2.92e-2)" "unprognostic (1.10e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.34e-2)" "prognostic unfavorable (1.13e-8)" "unprognostic (8.40e-3)" "unprognostic (1.15e-1)" "unprognostic (1.82e-2)" "prognostic favorable (3.56e-4)" 0.2 0.0 0.2 1.1 0.6 6.5 0.7 0.0 0.5 0.3 0.1 1.7 3.6 0.2 0.2 0.8 0.5 1.7 0.0 0.1 0.1 0.0 0.1 6.6 0.5 0.1 0.2 0.4 0.1 0.1 0.0 0.1 0.1 0.3 1.5 0.0 1.2 0.4 0.0 0.4 5.9 0.2 0.1 0.8 2.8 0.7 0.2 4.2 0.3 0.0 1.5 0.9 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 12.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.6 1.6 0.1 0.5 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.5 0.2 0.6 0.0 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 32.7 6.4 25.7 10.4 65.4 30.0 38.9 74.2 33.0 15.8 45.0 58.5 59.6 38.6 33.9 14.7 8.4 27.6 62.5 25.1 92.0 35.6 54.5 39.8 35.3 34.0 28.2 36.2 8.9 65.6 58.5 42.4 18.8 47.0 67.4 22.8 42.8 53.2 53.0 6.7 7.8 25.1 67.1 42.3 44.9 40.3 26.8 50.8 58.7 1.9 54.1 61.1 53.5 9.0 15.7 56.8 21.3 29.7 61.1 48.8 40.3 81.5 31.3 19.6 26.3 21.3 43.7 107.3 33.3 53.8 41.3 13.1 68.0 35.0 39.3 38.5 ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Hepatic stellate cells: 82.1;Squamous epithelial cells: 108.4;Suprabasal keratinocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 103.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" 36.3 13.7 5.7 16.9 5.9 203.2 25.4 5.3 10.5 31.6 15.5 13.6 3.1 16.3 3.7 52.9 15.1 21.2 72.5 5.5 6.6 18.0 13.3 38.5 10.4 8.0 6.3 29.1 9.4 8.0 15.9 26.8 6.4 14.0 5.0 1.7 14.1 9.0 10.1 66.3 8.8 18.2 7.0 12.6 12.3 7.4 8.0 12.8 21.1 10.4 11.9 23.7 43.5 7.7 6.4 16.1 19.2 8.6 32.8 31.4 10.9 35.0 75.9 25.8 32.0 1.2 2.8 11.2 7.7 22.5 51.2 20.7 6.5 17.4 26.6 9.6 7.6 6.6 24.6 4.9 64.3 15.9 12.3 29.2 103.5 53.8 42.8 29.9 48.7 11.4 28.4 21.5 32.0 2.7 3.1 17.0 14.3 2.2 17.9 14.3 9.9 6.8 10.6 2.8 10.7 7.0 6.7 7.8 16.0 11.6 0.6 11.8 82.7 51.9 13.6 34.5 34.5 7.8 9.8 7.3 38.0 27.9 24.8 4.4 9.5 14.0 4.5 5.8 4.5 2.5 2.7 2.6 6.2 2.8 3.2 2.9 30.6 5.0 5.8 4.2 2.3 21.3 5.7 5.9 5.3 10.5 5.5 6.6 8.0 6.3 6.4 7.0 8.0 7.7 98.0 3.2 8.3 1.3 9.0 37.9 15.3 13.2 44.3 0.0 3.0 2.4 7.8 1.5 9.0 3.7 0.0 7.3 37.0 1.7 0.0 3.7 6.3 11.7 10.0 42.5 0.0 8.8 0.6 2.4 22.6 15.5 3.6 46.7 20.3 3.6 82.1 2.3 10.8 0.0 0.4 2.6 2.0 17.2 20.6 1.6 5.0 28.1 8.8 6.5 7.0 3.8 10.3 0.5 0.9 3.0 0.5 5.7 13.6 5.8 0.2 0.5 5.2 0.6 13.1 6.3 14.7 8.1 1.8 108.4 72.7 5.1 23.8 4.4 1.1 20.5 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.8" "Cell type enhanced" "Detected in all" "Langerhans cells: 195.0" "Cancer enhanced" "Detected in all" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 73.8;SuSa: 78.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "CAB069890: AB_10000529, HPA063889: AB_2685143" "unprognostic (5.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (4.87e-3)" "unprognostic (6.35e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (3.26e-3)" "unprognostic (7.04e-2)" "unprognostic (4.48e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" 7.3 4.7 6.7 9.2 7.1 57.8 6.0 23.6 8.7 5.3 3.7 5.0 5.7 5.0 6.7 13.7 3.9 4.4 6.4 7.5 6.2 4.1 3.6 7.2 9.0 7.1 6.8 5.7 3.5 3.6 4.4 7.1 7.8 4.5 4.6 20.0 6.4 3.3 11.8 13.4 6.8 4.1 5.2 10.6 7.0 16.0 8.0 20.0 3.8 4.3 9.8 5.8 6.8 8.2 12.4 8.5 34.0 19.6 4.1 4.0 33.5 3.5 8.3 4.5 5.5 8.8 9.4 6.5 12.3 7.1 6.8 6.3 8.0 20.1 4.1 13.0 12.4 23.3 10.6 11.6 4.6 23.9 26.3 5.7 12.3 6.6 26.2 13.4 4.7 73.8 30.5 10.8 2.7 12.6 47.6 44.6 36.4 6.1 3.8 20.9 10.4 18.6 4.2 13.0 26.2 15.0 7.3 24.9 32.1 78.1 8.7 25.0 8.5 20.6 11.4 11.5 12.3 6.9 17.8 11.7 7.0 21.9 26.6 10.1 3.8 3.2 3.4 2.4 2.9 2.5 1.6 2.1 3.1 3.4 2.1 2.9 13.2 4.9 2.7 4.4 1.4 2.1 6.7 7.1 23.6 8.7 7.5 6.2 7.1 6.8 7.8 5.2 8.0 8.2 30.1 6.4 12.8 175.3 40.7 80.4 10.7 23.0 31.9 74.2 28.3 23.1 10.5 15.7 17.1 5.5 87.6 27.0 62.9 10.0 1.9 8.2 89.2 30.7 18.0 27.1 26.8 50.9 125.9 4.4 25.0 17.6 19.9 77.5 25.3 14.8 15.7 13.8 24.0 154.8 124.4 16.4 16.2 61.3 195.0 40.8 8.7 89.5 26.6 97.4 49.1 134.0 54.6 136.7 136.6 15.6 9.3 8.6 34.9 6.8 16.6 3.8 8.7 89.7 6.6 18.1 23.6 9.4 71.1 43.4 151.6 25.2 43.2 17.4 14.7 15.4 JMJD6 "KIAA0585, PTDSR, PTDSR1" ENSG00000070495 "Jumonji domain containing 6, arginine demethylase and lysine hydroxylase" Q6NYC1 17 76712832-76726799 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 121.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004548, HPA059156" Supported Supported Nucleoplasm No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB004548: AB_628185, HPA059156: AB_2683934" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (8.06e-2)" "unprognostic (9.46e-2)" "unprognostic (5.95e-2)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.75e-6)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.56e-2)" "prognostic favorable (5.71e-4)" "unprognostic (5.66e-2)" "prognostic unfavorable (7.59e-7)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (8.86e-2)" "unprognostic (3.82e-1)" 30.3 27.0 14.2 17.0 16.3 121.7 19.6 19.2 29.5 20.2 15.3 32.3 15.4 19.4 7.4 18.8 22.4 18.7 41.2 14.3 16.5 18.3 18.5 26.8 15.7 16.2 16.2 27.6 18.0 11.0 22.4 16.2 16.2 19.9 10.3 29.5 15.2 10.7 38.2 15.6 18.4 16.0 14.6 21.1 24.4 17.8 16.9 13.4 16.6 28.1 12.8 23.9 20.4 20.8 39.0 53.3 18.0 23.5 22.6 19.4 17.6 34.7 26.8 49.6 47.6 53.6 18.7 25.3 14.9 37.6 72.6 28.8 57.3 17.3 47.2 18.6 45.9 37.3 37.5 54.4 36.8 19.7 55.0 23.9 26.8 54.2 18.2 31.6 41.6 13.8 57.1 45.2 37.0 24.4 34.7 28.4 15.9 37.3 62.4 27.1 33.6 39.2 16.6 12.1 31.1 31.1 30.2 43.7 43.7 30.4 39.5 28.6 27.7 56.7 33.3 29.9 65.8 50.6 28.8 23.4 55.7 17.4 32.5 50.8 28.6 40.2 24.7 37.8 24.0 20.5 28.4 28.2 25.9 13.0 23.3 22.2 23.3 14.6 39.4 22.4 31.0 20.1 14.2 16.3 19.2 29.5 14.3 16.5 16.2 16.2 16.2 14.6 16.9 20.8 44.1 25.6 22.9 9.1 29.3 83.2 79.9 46.1 67.2 16.5 30.8 42.8 30.5 14.3 29.2 9.2 50.1 29.0 96.5 33.1 17.6 28.1 30.3 39.1 29.6 36.0 39.4 13.0 6.6 27.4 52.9 37.9 33.1 58.6 65.2 18.6 28.2 10.2 32.7 6.7 7.4 32.0 24.4 19.5 79.2 12.5 16.1 52.4 58.7 3.7 26.9 11.8 21.6 7.1 7.9 29.6 32.1 17.7 50.0 38.5 40.8 7.9 20.5 35.4 13.1 32.7 69.2 59.6 27.2 48.8 73.6 30.5 80.4 29.9 31.3 60.2 JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001168 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "HPA001168: AB_1079162" "unprognostic (6.50e-2)" "unprognostic (1.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.46e-1)" "unprognostic (1.83e-3)" "unprognostic (1.06e-1)" "unprognostic (4.41e-1)" "unprognostic (2.88e-2)" "unprognostic (4.41e-1)" 33.6 22.1 30.7 25.0 32.6 89.6 25.0 30.9 34.2 24.0 23.2 40.9 27.5 25.6 14.8 23.0 28.0 34.1 24.6 33.0 27.7 20.0 23.8 30.9 21.8 29.9 28.7 48.9 25.9 16.8 27.8 22.7 30.6 23.1 38.4 21.5 21.3 18.2 24.4 27.4 35.8 27.8 29.2 22.7 24.8 19.2 29.2 27.9 22.3 22.0 24.3 33.1 22.9 32.6 69.6 24.5 35.1 45.7 44.1 53.5 26.6 52.2 62.1 66.5 69.3 40.5 34.4 66.3 26.4 52.6 44.3 43.8 49.2 46.4 53.4 71.4 32.6 35.2 57.3 34.9 74.9 63.8 33.1 46.7 67.8 62.9 107.1 58.3 79.8 41.0 32.0 68.2 49.4 29.4 27.9 25.9 13.3 41.8 27.5 49.5 51.5 27.9 36.1 35.3 32.3 17.4 59.9 29.3 54.7 29.2 29.4 18.2 70.0 39.4 48.1 51.4 32.1 74.9 71.1 54.2 52.4 33.5 37.5 1.0 1.8 1.9 2.6 2.8 1.8 1.6 2.2 3.4 1.3 1.6 2.3 3.7 3.6 2.3 1.6 1.0 3.2 1.4 30.7 32.6 30.9 34.2 33.0 27.7 29.9 28.7 30.6 29.2 29.2 32.6 45.0 25.6 17.1 12.7 53.1 46.4 75.0 20.2 34.7 28.2 41.0 45.1 17.0 44.3 18.5 36.8 22.9 10.5 94.1 133.1 13.7 34.6 4.9 51.6 38.6 35.3 23.4 21.0 25.2 39.3 15.0 24.2 53.5 114.5 16.5 26.9 23.9 24.8 22.7 18.5 21.7 61.8 12.2 32.6 106.3 4.8 12.8 74.2 16.0 6.5 27.3 27.5 12.3 7.1 24.6 68.0 88.1 13.9 61.5 62.4 64.6 18.1 17.4 23.6 13.1 27.9 27.3 16.2 24.2 35.5 51.6 12.9 75.2 17.8 35.0 102.7 KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" 5.9 7.6 5.6 11.4 7.6 27.2 6.3 5.3 7.8 7.6 7.6 14.1 8.0 5.7 3.7 9.1 13.4 6.0 6.8 6.6 5.9 7.8 7.4 8.8 10.4 6.9 6.7 6.7 5.9 3.2 5.8 4.6 6.1 5.2 12.2 12.0 5.7 4.7 17.3 11.2 8.9 6.9 6.2 10.5 5.6 15.7 5.6 10.8 27.2 9.1 9.4 7.7 8.1 9.4 15.1 9.7 11.2 23.0 13.8 20.5 24.5 11.7 12.6 7.5 10.2 16.3 7.4 34.1 31.6 19.2 22.8 15.5 17.8 20.8 16.0 31.6 14.6 17.2 8.6 15.0 6.7 25.5 17.5 10.3 23.4 21.5 17.7 12.1 7.7 15.9 38.3 5.2 12.7 12.6 14.1 10.5 3.8 31.6 12.8 26.8 20.3 24.4 10.7 19.8 34.2 10.6 9.7 23.5 22.9 11.7 22.3 20.3 6.5 16.9 9.5 11.9 15.5 5.2 15.9 20.0 6.4 18.9 37.8 1.2 4.6 7.2 0.5 8.6 0.3 1.2 0.5 0.5 3.7 1.3 0.5 0.2 4.9 0.3 6.9 1.6 0.7 1.3 5.6 7.6 5.3 7.8 6.6 5.9 6.9 6.7 6.1 6.2 5.6 9.4 4.9 0.0 8.2 14.7 8.7 12.7 5.7 3.8 7.4 5.0 7.6 6.6 10.4 11.5 10.4 1.8 10.4 2.7 3.0 23.0 1.9 6.6 0.7 36.2 10.0 4.2 6.7 3.8 19.0 4.3 5.1 5.8 8.2 15.5 2.5 3.3 4.2 7.7 7.5 5.0 10.8 9.6 10.2 36.7 11.7 0.7 3.7 20.6 7.2 22.5 27.7 6.6 8.2 16.1 23.8 7.2 21.2 6.8 3.7 5.4 6.2 11.2 21.0 15.5 0.0 6.9 6.2 0.7 18.2 9.7 15.9 1.4 5.6 3.1 10.6 6.6 KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119263-67258082 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (7.43e-2)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (8.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (2.84e-1)" "unprognostic (4.46e-1)" "unprognostic (2.04e-3)" "unprognostic (3.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "unprognostic (9.45e-3)" 19.5 13.2 10.7 27.2 10.6 47.1 19.7 18.0 12.1 24.3 14.1 23.3 14.7 29.1 17.4 31.9 19.3 19.0 17.4 10.6 11.2 14.3 19.9 24.0 27.5 12.6 10.7 24.5 13.0 16.1 13.1 18.0 10.9 21.6 17.1 18.5 21.3 19.2 33.8 29.4 23.9 24.0 9.7 27.0 18.9 29.0 11.9 27.8 19.0 24.5 28.7 23.9 25.9 10.9 49.9 31.8 17.6 27.7 17.1 27.0 13.5 21.5 26.6 41.0 27.9 48.7 25.4 38.8 37.5 33.3 23.8 48.2 31.3 22.5 33.1 66.4 13.4 28.9 39.2 11.7 16.9 24.5 38.1 21.7 23.9 39.4 25.7 20.7 29.9 22.7 27.4 54.4 18.6 35.4 32.5 18.1 36.1 29.8 25.6 39.9 29.4 21.4 14.7 33.7 24.2 18.9 71.0 38.6 39.0 21.6 59.9 23.9 38.7 25.0 16.7 34.5 18.8 29.3 35.4 25.4 22.0 17.2 17.8 0.4 1.1 0.3 2.5 0.8 2.7 3.6 1.9 2.3 0.6 3.6 1.9 1.9 2.7 2.7 0.5 0.9 2.6 1.9 10.7 10.6 18.0 12.1 10.6 11.2 12.6 10.7 10.9 9.7 11.9 10.9 41.4 38.5 35.8 75.1 56.6 41.2 23.3 23.4 75.7 75.3 40.3 30.9 31.1 34.3 31.0 16.5 137.6 23.9 77.5 43.2 0.0 17.3 20.6 84.8 63.0 38.4 31.8 22.1 89.4 14.5 13.4 32.4 42.8 112.3 27.3 42.1 29.3 35.5 21.5 95.9 89.8 27.5 24.4 46.5 59.6 11.2 21.5 49.1 19.6 104.0 43.3 19.8 33.0 96.0 99.5 25.9 25.5 23.0 72.5 37.2 21.2 10.3 40.0 111.7 19.7 40.2 32.3 52.0 38.1 78.7 47.7 32.3 66.9 33.8 29.5 48.7 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KDM7A "JHDM1D, KIAA1718" ENSG00000006459 "Lysine demethylase 7A" Q6ZMT4 7 140084746-140176983 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012114 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA012114: AB_1852429" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "unprognostic (4.08e-3)" "unprognostic (3.52e-1)" "unprognostic (1.69e-2)" "unprognostic (4.00e-1)" "unprognostic (3.44e-2)" "unprognostic (2.56e-1)" "unprognostic (3.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.29e-1)" "unprognostic (9.55e-2)" "unprognostic (3.42e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" 6.6 2.1 2.1 6.9 1.6 16.4 4.7 3.8 3.9 9.5 1.5 8.4 8.2 6.6 1.4 7.0 2.9 4.5 4.1 2.7 1.6 3.6 6.7 4.8 7.0 2.5 2.5 2.1 4.5 4.1 1.3 9.1 2.8 3.3 9.3 5.8 5.1 2.1 12.6 7.5 8.3 4.4 2.4 5.6 9.3 7.7 3.7 6.7 2.8 13.2 8.0 5.7 3.7 3.0 0.8 0.4 2.7 2.8 2.4 2.3 5.4 1.2 1.7 0.4 0.5 0.2 0.4 1.9 1.9 1.3 1.4 1.0 3.7 2.3 0.8 10.8 2.3 0.1 0.4 5.1 2.5 1.8 1.9 2.4 5.1 1.4 8.0 1.3 2.6 5.0 6.1 8.2 0.5 0.8 3.6 3.1 4.3 6.3 1.5 3.8 0.2 4.0 0.9 1.2 4.7 5.8 2.8 6.5 2.7 4.3 8.8 0.7 4.6 0.5 1.0 1.7 0.8 2.9 0.4 6.2 1.5 5.0 1.0 0.6 0.8 0.3 0.3 0.4 0.3 0.5 0.5 0.5 1.1 1.1 0.5 0.3 2.2 0.6 0.2 0.4 0.4 0.3 2.1 1.6 3.8 3.9 2.7 1.6 2.5 2.5 2.8 2.4 3.7 3.0 34.4 16.0 25.5 25.5 30.6 49.8 44.8 17.7 8.0 11.8 11.1 7.4 14.6 8.6 30.1 16.5 27.1 12.3 17.8 36.7 1.9 7.2 5.2 17.0 18.2 23.8 52.7 32.4 35.3 9.4 2.8 20.0 30.5 28.7 8.2 12.2 18.5 18.5 10.7 6.7 34.8 38.0 12.2 31.4 86.7 4.9 7.8 35.4 3.6 96.5 34.7 4.3 10.3 35.7 36.0 12.2 28.7 4.1 11.8 35.3 26.9 3.3 33.3 9.2 6.6 14.9 17.8 31.2 14.3 12.3 46.5 37.9 18.5 3.4 27.2 50.0 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KLHL28 "BTBD5, FLJ20081" ENSG00000179454 "Kelch like family member 28" Q9NXS3 14 44924324-45042322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000988 Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA000988: AB_1845480" "unprognostic (8.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (7.84e-3)" "unprognostic (9.20e-2)" "unprognostic (4.36e-3)" "unprognostic (4.92e-2)" "unprognostic (2.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.68e-2)" "unprognostic (7.55e-2)" "unprognostic (4.34e-1)" "unprognostic (1.75e-2)" "unprognostic (6.53e-2)" 4.6 4.8 2.6 6.5 3.4 27.0 5.7 9.0 3.6 5.2 3.3 5.0 5.1 5.3 5.0 6.5 5.4 5.5 4.1 2.9 3.9 4.6 6.4 5.6 8.7 3.2 2.9 7.8 3.8 4.2 3.0 5.6 3.5 5.5 6.0 8.1 4.3 3.9 4.7 5.1 5.0 5.8 3.3 5.8 5.0 7.3 3.3 9.2 7.6 8.0 7.4 5.6 3.5 6.4 4.5 6.7 8.6 5.6 7.7 6.8 6.5 5.8 6.4 8.4 7.1 3.0 6.8 6.6 6.2 10.1 2.2 7.6 7.7 6.1 9.2 12.3 4.2 5.7 6.9 3.4 6.9 9.2 12.0 5.3 8.6 5.4 8.6 4.8 6.8 10.2 5.1 16.0 4.9 6.5 7.4 4.7 5.3 5.0 6.3 6.3 9.6 3.7 4.8 8.0 9.8 6.0 7.5 5.0 8.1 5.5 9.4 3.9 8.7 7.5 8.6 5.3 3.3 9.4 11.0 9.2 2.6 4.1 4.6 31.5 7.3 18.3 17.0 10.2 31.5 14.9 17.0 18.0 6.4 13.0 20.0 17.2 16.8 20.3 11.2 8.7 14.2 6.9 2.6 3.4 9.0 3.6 2.9 3.9 3.2 2.9 3.5 3.3 3.3 6.4 15.7 16.0 9.4 17.0 30.1 24.5 16.4 20.1 27.9 24.8 12.9 10.4 12.1 11.5 17.6 18.4 35.5 7.7 27.5 14.9 7.9 10.0 40.2 20.0 13.6 15.4 13.9 27.8 32.6 5.6 8.3 18.0 17.3 9.7 19.0 10.2 16.8 13.1 9.2 15.2 30.0 12.1 6.1 15.8 23.6 62.8 21.8 19.1 23.2 16.9 15.7 23.2 23.7 36.7 40.4 10.3 12.7 17.7 27.0 12.6 13.1 8.5 32.3 23.4 13.1 14.6 19.8 10.8 5.1 19.4 30.1 14.1 38.6 7.7 9.5 15.8 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409353 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 13.7 10.1 22.6 15.3 22.1 39.2 13.1 20.8 23.2 22.2 18.7 17.7 12.8 21.3 12.9 40.7 21.7 13.6 17.0 22.2 20.6 13.7 14.0 15.5 15.4 22.4 22.7 12.0 19.7 11.4 10.7 16.5 22.9 30.2 14.4 11.7 24.0 19.7 24.4 28.1 15.6 16.7 21.4 16.8 16.9 7.9 23.3 17.9 25.7 15.3 16.6 16.6 25.7 23.9 37.3 24.3 27.8 43.5 18.1 30.9 40.1 57.4 26.3 32.0 26.9 28.8 21.9 84.9 33.1 37.5 11.7 35.8 41.6 21.7 33.3 39.3 45.0 68.8 26.4 15.2 26.5 54.8 18.8 15.1 27.1 34.7 32.8 30.2 26.2 36.4 136.8 38.1 27.5 29.9 58.1 84.9 13.8 34.6 29.0 70.4 22.1 24.1 22.8 43.4 37.9 30.9 51.3 28.3 28.6 23.6 39.6 75.3 32.4 35.2 26.0 42.3 42.3 23.0 25.9 75.9 24.6 29.6 29.9 2.3 1.2 4.3 1.3 2.1 2.7 1.7 1.6 2.1 1.0 1.1 0.9 1.1 1.8 2.3 2.1 2.0 1.5 0.3 22.6 22.1 20.8 23.2 22.2 20.6 22.4 22.7 22.9 21.4 23.3 23.9 34.5 12.8 14.5 0.0 12.7 0.0 17.6 0.0 20.5 20.8 32.0 27.3 0.0 7.2 6.8 27.6 6.2 15.1 22.4 10.4 7.9 9.2 10.1 46.8 43.8 20.7 4.9 62.1 0.0 9.4 16.6 14.7 15.8 41.1 2.5 21.3 30.4 19.5 17.7 3.3 0.0 22.2 0.0 16.8 0.0 3.2 16.1 19.6 0.0 0.0 3.4 28.7 7.2 0.0 0.0 13.6 9.6 42.9 15.9 24.1 14.3 13.1 11.7 17.9 6.6 23.2 19.7 9.7 10.2 38.8 0.0 14.2 14.5 18.4 12.7 22.5 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KRAS "KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25205246-25250936 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049830 Approved NA NA 3300000 "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "HPA049830: AB_2680903" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (3.74e-2)" "unprognostic (1.79e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (6.42e-2)" "prognostic favorable (2.75e-5)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.81e-2)" "unprognostic (9.97e-2)" 11.8 9.1 11.0 16.2 12.2 27.8 10.0 11.7 12.3 9.5 4.6 22.0 14.0 11.0 6.8 19.3 7.4 13.1 8.6 12.5 12.0 11.7 15.3 13.2 17.9 8.5 9.7 8.0 12.6 11.1 5.7 17.0 8.7 11.8 23.0 22.7 11.9 8.3 7.6 13.6 19.5 13.6 8.1 12.0 20.3 8.9 12.9 17.2 10.8 10.3 17.4 16.2 11.4 8.6 15.9 14.3 39.4 20.7 14.1 19.9 68.9 17.3 22.8 18.0 21.9 51.5 30.7 38.7 10.4 32.0 23.4 18.6 44.9 17.3 34.3 26.7 15.0 37.6 17.6 15.6 15.8 32.8 25.6 18.1 25.5 21.9 20.2 33.6 27.1 28.7 28.0 17.3 27.6 14.1 46.8 56.6 87.6 25.3 7.4 43.4 39.9 59.9 27.2 22.4 11.2 32.4 20.5 24.9 21.8 97.4 28.9 26.9 28.1 18.7 24.8 38.2 22.0 16.4 28.5 41.9 15.4 20.0 15.0 31.2 8.1 13.7 11.6 16.4 7.9 10.7 10.1 13.1 7.9 10.5 13.8 12.4 19.2 11.2 22.4 7.8 7.6 5.8 11.0 12.2 11.7 12.3 12.5 12.0 8.5 9.7 8.7 8.1 12.9 8.6 73.7 48.1 32.1 16.6 90.8 100.9 96.4 57.2 72.3 63.4 59.9 38.0 16.3 64.3 53.6 38.6 73.0 94.2 66.0 161.9 58.7 77.5 3.9 45.4 40.8 77.3 78.8 60.2 42.0 91.8 21.4 50.1 98.4 53.4 24.1 26.6 77.8 56.9 51.5 92.5 45.3 92.9 36.7 53.9 83.7 5.9 40.7 75.3 62.2 28.1 82.9 41.7 49.4 19.6 16.6 114.2 104.7 51.6 85.0 130.1 63.0 52.3 42.5 65.8 26.3 53.7 52.2 53.0 40.3 93.0 155.7 139.1 83.0 36.5 96.7 176.9 LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4054.2;Club cells: 5757.0;Ductal cells: 6457.0;Pancreatic endocrine cells: 5424.3;Respiratory ciliated cells: 3161.5;Urothelial cells: 7112.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 11 "CAPAN-2: 3623.8;EFO-21: 1450.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" 4.9 3.6 0.0 125.5 0.1 2768.7 22.0 0.1 0.5 810.5 2.0 249.1 34.4 14.2 20.5 677.6 52.6 2223.2 3.1 0.0 0.1 31.6 67.8 76.1 1.1 0.3 0.1 1.1 74.8 7.3 21.2 2.6 0.3 74.5 131.0 0.0 1308.3 13.5 1.2 28.1 157.3 11.9 0.1 82.0 363.9 0.5 0.1 14.2 27.1 0.3 199.1 669.9 480.7 0.1 117.7 35.1 0.0 4.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3623.8 0.2 1450.9 0.0 3.7 236.4 0.0 6.9 0.1 5.3 0.0 30.4 0.0 0.8 0.2 0.0 1.1 0.1 230.4 0.0 12.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.9 80.9 0.2 0.2 0.3 0.3 1.0 20.1 0.1 0.1 2.0 65.3 1.0 0.0 8.4 1.8 0.0 2.9 16.9 0.0 2.9 0.6 4.6 4.7 0.2 0.6 2.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 4.7 0.0 0.0 12.1 0.0 0.1 0.1 0.5 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.1 0.2 0.0 20.8 0.0 15.9 0.3 376.6 4054.2 1.8 0.0 38.1 29.3 0.2 1328.2 5757.0 138.0 0.0 0.8 1.2 315.6 0.0 6457.0 2.0 25.6 4.3 11.5 57.9 11.2 0.0 1837.0 0.3 12.2 237.0 52.3 13.4 0.0 2.2 43.2 0.6 0.0 0.0 264.3 956.2 2.7 0.0 15.8 3.4 34.9 0.0 0.0 60.3 0.0 1.0 0.0 0.0 5424.3 183.4 0.0 1.4 420.6 509.8 1.6 3161.5 0.0 0.0 0.0 337.7 0.0 0.3 51.1 0.0 0.3 7.7 0.0 475.5 7112.9 LDB1 "CLIM2, NLI" ENSG00000198728 "LIM domain binding 1" Q86U70 10 102106489-102120368 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034488 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA034488: AB_10669783" "unprognostic (8.83e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-3)" "unprognostic (4.54e-2)" "unprognostic (1.35e-1)" "unprognostic (5.01e-3)" "unprognostic (1.55e-2)" "unprognostic (1.04e-3)" "unprognostic (2.33e-1)" "unprognostic (1.63e-1)" "unprognostic (1.09e-3)" "unprognostic (8.25e-2)" "unprognostic (2.54e-1)" "unprognostic (3.19e-1)" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (1.26e-2)" 41.3 38.0 48.0 42.9 51.2 122.4 44.0 42.8 57.4 89.1 55.8 73.8 31.1 81.5 38.1 54.1 68.9 49.1 60.6 49.4 47.0 40.5 20.5 46.6 61.5 42.1 42.2 117.9 29.4 55.6 52.3 49.1 40.0 58.4 27.5 41.6 65.6 71.6 52.5 149.9 51.7 52.8 38.2 60.8 44.4 30.6 45.8 59.3 49.5 31.6 55.3 65.4 72.4 48.5 42.6 53.5 105.8 128.0 41.3 44.6 52.7 43.8 70.2 48.7 42.3 38.3 36.3 64.8 60.8 56.7 23.0 85.8 48.9 87.3 25.9 55.7 46.9 208.2 62.7 38.6 49.0 56.1 67.8 97.4 70.0 40.2 46.3 177.3 52.0 59.7 128.3 69.1 38.6 41.9 101.1 89.5 52.1 20.4 26.4 112.0 68.4 46.9 46.7 47.3 42.6 103.8 30.9 34.1 51.6 69.0 162.5 36.3 53.8 29.5 60.0 26.8 37.3 58.7 54.4 44.3 49.7 125.7 27.2 2.9 2.0 1.9 2.1 2.9 1.3 2.0 1.5 2.1 1.3 2.4 2.0 1.6 4.8 2.0 4.9 1.4 1.6 1.3 48.0 51.2 42.8 57.4 49.4 47.0 42.1 42.2 40.0 38.2 45.8 48.5 6.4 32.1 11.0 5.2 8.1 22.8 2.8 4.6 17.6 18.5 8.4 7.9 9.1 2.8 6.9 3.7 4.2 4.8 11.7 3.2 0.0 7.7 2.1 7.7 11.1 6.9 8.3 17.0 9.8 5.6 6.3 7.0 5.6 9.3 9.5 9.5 5.3 2.2 8.9 15.2 10.4 1.4 4.1 5.4 7.5 3.0 6.2 7.3 3.6 12.2 4.0 11.8 6.2 5.5 6.6 7.5 2.0 6.4 7.7 2.7 1.9 1.4 3.5 6.1 0.0 6.9 8.2 7.6 7.3 10.7 21.2 7.8 10.0 10.3 2.6 2.0 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 2.8 3.2 3.3 9.0 3.2 34.5 3.6 3.6 3.5 5.5 2.3 6.8 8.6 4.0 2.5 7.4 5.9 2.3 1.6 2.9 3.2 2.9 4.0 3.4 15.6 4.4 2.9 6.0 7.0 4.2 4.8 5.1 4.5 4.0 4.2 2.7 4.8 3.0 3.8 10.4 9.6 2.2 2.6 6.0 5.2 8.2 3.1 20.7 5.1 1.0 9.7 3.5 5.0 3.9 43.4 64.1 57.1 37.6 2.6 4.2 41.7 27.0 19.1 44.1 47.2 35.0 42.9 83.7 15.3 11.2 11.9 30.1 24.7 26.7 16.9 45.2 48.8 56.4 38.7 47.5 1.0 63.0 43.7 5.7 2.5 23.0 3.4 5.0 24.0 51.0 46.3 29.8 23.3 44.0 107.3 123.7 33.6 46.7 15.9 84.1 48.4 43.6 12.3 64.8 36.3 36.5 32.3 33.6 10.1 12.5 22.7 44.5 22.6 31.7 54.3 23.9 40.3 29.3 49.0 83.1 12.7 38.0 33.3 0.0 1.6 2.6 7.8 6.8 7.7 10.9 8.8 8.3 1.6 10.0 11.5 8.2 1.3 12.1 3.3 1.5 10.9 5.7 3.3 3.2 3.6 3.5 2.9 3.2 4.4 2.9 4.5 2.6 3.1 3.9 3.9 3.2 13.6 5.9 16.1 8.3 9.5 8.7 24.5 21.5 7.8 12.3 3.9 7.2 10.3 3.7 10.4 31.1 9.6 10.2 7.9 5.8 19.3 12.0 5.1 8.3 0.0 36.2 4.2 5.2 35.8 6.8 5.1 8.3 6.3 23.1 5.0 5.3 16.4 8.4 5.6 10.0 6.1 3.5 6.8 8.5 2.1 6.6 3.6 3.7 7.2 10.9 11.3 3.5 8.4 3.0 4.4 1.9 23.0 2.8 7.6 4.7 19.5 11.3 13.1 4.5 6.5 13.5 26.1 15.9 9.1 10.0 13.9 6.0 15.3 8.7 LLPH "C12orf31, hLLP, MGC14817" ENSG00000139233 "LLP homolog, long-term synaptic facilitation factor" Q9BRT6 12 66116555-66130750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048920, HPA058786" Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli "Mitotic chromosome" "HPA048920: AB_2680556, HPA058786: AB_2683820" "unprognostic (3.60e-3)" "unprognostic (4.94e-2)" "unprognostic (4.07e-2)" "unprognostic (3.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.31e-2)" "prognostic unfavorable (6.44e-7)" "unprognostic (7.15e-2)" "unprognostic (1.30e-2)" "unprognostic (8.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.07e-2)" "unprognostic (3.87e-2)" "unprognostic (9.65e-3)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (2.94e-2)" 21.6 34.4 12.3 24.4 13.5 50.3 18.6 12.7 16.0 13.2 11.2 20.1 19.2 15.2 18.6 19.5 13.2 14.7 23.2 12.8 13.7 20.9 21.2 15.5 26.3 13.5 14.3 17.6 17.2 17.0 10.7 17.5 13.7 15.3 20.3 7.4 14.5 14.1 29.7 13.8 18.2 19.4 13.0 18.2 19.1 22.1 13.5 22.1 17.3 25.3 25.6 27.3 14.0 14.2 77.0 61.1 36.4 44.2 42.6 40.8 44.5 87.0 56.4 63.9 53.6 52.8 31.0 87.0 70.6 58.6 50.7 63.6 57.2 52.9 85.7 78.4 48.8 94.5 41.7 47.3 49.8 162.5 61.8 41.9 53.6 53.7 58.3 50.1 56.6 44.1 81.5 60.9 76.1 81.3 74.1 110.4 77.9 61.6 63.0 61.9 67.2 62.7 63.3 90.8 36.3 45.1 57.0 58.3 97.4 38.0 77.4 89.5 60.5 48.3 71.3 60.9 80.4 45.7 77.6 130.2 65.4 76.0 76.8 34.3 32.0 35.5 27.8 38.0 32.0 29.2 32.3 30.6 31.3 27.5 27.4 29.2 43.8 27.4 48.4 27.0 38.9 28.8 12.3 13.5 12.7 16.0 12.8 13.7 13.5 14.3 13.7 13.0 13.5 14.2 34.2 12.8 33.9 2.9 47.6 27.1 53.9 86.3 30.1 15.9 24.5 28.4 25.1 41.5 64.3 31.3 4.2 66.3 49.4 34.1 66.5 68.3 63.3 40.5 45.4 32.5 13.8 33.4 5.0 71.3 70.4 34.8 35.7 46.6 89.4 61.2 35.7 60.2 64.2 21.9 4.4 31.1 85.5 50.4 26.5 17.0 43.8 45.6 35.6 3.7 84.1 30.8 59.8 3.0 5.8 96.3 43.3 30.1 27.3 46.3 44.0 86.5 35.8 15.2 26.3 29.7 36.8 126.6 48.6 30.6 30.5 72.7 43.8 126.4 36.1 60.6 LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007872-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1" "Cell type enhanced" "Detected in many" "Early spermatids: 101.9;Excitatory neurons: 45.4;Spermatocytes: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Group enriched" "Detected in many" 4 "granulocytes: 1.5;NK-cells: 3.8;T-cells: 2.6" "Low cell line specificity" "Detected in all" HPA015135 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" 4.7 3.7 7.5 3.7 6.6 25.1 5.2 13.7 10.3 6.9 0.9 4.9 3.4 6.2 4.7 4.2 6.8 3.6 2.6 8.0 4.2 3.6 2.1 5.6 4.6 4.8 3.4 9.1 3.2 5.7 8.3 3.5 5.2 4.7 4.6 6.9 4.7 2.8 3.5 10.5 5.0 5.2 2.2 6.2 5.0 17.9 5.1 10.9 4.1 1.4 4.5 4.6 5.9 7.1 2.7 5.0 15.6 8.9 3.9 4.7 4.8 2.4 9.0 6.9 8.7 6.8 2.6 7.1 5.0 5.5 8.5 3.6 9.3 1.9 5.4 2.2 7.6 3.4 8.1 2.6 5.8 13.3 5.8 5.1 5.9 6.3 15.9 6.6 5.9 12.1 8.2 6.8 2.6 2.5 23.4 20.5 4.8 2.5 3.3 16.2 3.7 5.9 3.9 6.6 2.9 5.0 6.1 3.8 8.8 5.2 10.4 20.9 5.0 4.8 3.2 10.8 6.1 6.8 10.4 7.5 3.4 13.2 3.4 0.0 0.2 1.5 0.5 0.2 1.0 0.1 1.0 1.4 0.4 0.4 1.4 0.4 0.5 3.8 0.1 0.6 2.6 0.3 7.5 6.6 13.7 10.3 8.0 4.2 4.8 3.4 5.2 2.2 5.1 7.1 7.4 6.4 9.1 39.2 5.1 4.1 6.9 3.8 2.8 10.0 7.3 5.6 4.7 7.2 7.1 1.8 0.0 2.3 10.0 2.9 9.8 8.9 101.9 7.9 6.3 6.0 1.8 7.4 45.4 10.5 2.3 6.0 1.5 4.7 3.8 7.0 8.2 2.9 9.7 3.3 33.4 5.7 4.1 8.7 6.9 22.9 6.8 7.9 8.8 14.0 9.3 14.5 20.6 39.7 28.3 9.2 1.8 7.2 3.8 9.1 6.8 8.3 7.8 9.7 0.0 8.9 7.8 66.7 13.0 1.6 5.1 2.2 9.0 4.6 4.8 7.7 LSG1 FLJ11301 ENSG00000041802 "Large 60S subunit nuclear export GTPase 1" Q9H089 3 194640791-194672463 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037704, HPA037705" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 60: Granulocytes - Receptor signaling" "Nuclear bodies, Cytosol" Nucleoplasm "HPA037704: AB_10672912, HPA037705: AB_2675621" "unprognostic (5.72e-3)" "unprognostic (9.38e-3)" "unprognostic (2.63e-1)" "unprognostic (1.23e-2)" "unprognostic (3.74e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.21e-7)" "unprognostic (4.63e-2)" "unprognostic (1.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.60e-2)" "unprognostic (4.86e-3)" "unprognostic (1.42e-1)" "unprognostic (3.00e-2)" "unprognostic (2.70e-1)" "unprognostic (6.77e-2)" "unprognostic (2.07e-1)" 14.9 12.8 13.2 15.8 13.8 28.1 15.8 13.9 15.9 12.8 14.0 15.1 17.2 15.2 19.8 15.9 14.5 12.6 14.0 13.1 14.5 16.6 21.7 12.8 18.7 14.7 16.4 14.2 15.5 16.8 11.1 17.2 15.8 14.6 18.1 14.0 13.8 13.9 23.0 19.3 14.9 14.5 14.0 15.4 13.6 14.4 14.4 17.2 15.5 18.9 21.3 18.2 14.3 15.4 55.6 36.0 21.2 35.3 32.3 17.8 43.1 31.0 30.1 42.9 37.6 47.9 25.1 43.1 93.5 29.4 75.5 39.5 68.2 35.0 52.1 56.3 32.5 46.8 38.4 27.6 22.9 51.1 42.4 17.3 31.5 44.4 41.7 16.0 47.1 29.4 39.5 46.2 36.0 76.6 46.3 30.8 57.7 73.5 65.6 56.2 35.0 49.3 23.7 46.9 40.5 27.9 39.9 38.2 40.0 39.7 90.3 32.9 36.5 32.4 37.3 46.2 66.6 50.6 71.1 97.7 26.2 64.7 52.4 3.5 10.1 13.6 15.3 13.2 17.1 16.6 12.5 13.9 17.2 14.3 14.4 12.9 1.3 21.0 8.9 9.0 15.4 10.6 13.2 13.8 13.9 15.9 13.1 14.5 14.7 16.4 15.8 14.0 14.4 15.4 25.0 19.2 29.6 10.4 22.5 16.2 13.4 8.9 25.0 18.3 12.1 11.9 17.2 18.6 27.9 9.2 12.5 25.1 21.2 14.0 5.9 23.3 12.0 22.1 24.5 23.7 7.8 16.2 10.5 22.4 19.4 17.7 21.9 24.0 53.7 21.9 11.7 14.0 13.0 15.2 8.3 14.2 12.2 4.4 10.2 8.9 15.5 15.5 12.4 8.4 14.0 18.2 12.3 12.5 12.2 19.7 8.0 14.7 23.8 11.5 10.8 9.7 34.3 18.6 19.7 22.1 14.6 26.4 35.7 30.5 16.1 28.5 24.0 23.2 17.6 9.0 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 207.2;Kupffer cells: 255.8;monocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 86000000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 40.2 66.9 24.6 64.5 25.5 180.4 53.6 29.4 30.6 55.6 33.8 48.2 78.1 51.1 38.4 110.1 61.7 40.3 35.5 25.0 27.8 58.1 43.9 190.8 64.1 26.3 25.4 110.5 54.9 53.3 37.4 27.4 26.0 41.1 49.6 36.9 41.2 40.9 45.0 67.8 60.5 58.3 25.7 57.8 46.6 19.9 28.1 49.2 49.4 45.0 96.4 51.9 52.7 33.0 85.2 90.4 123.5 73.4 104.2 115.1 53.8 33.7 101.8 67.5 78.1 66.6 72.0 190.0 42.0 51.9 52.8 108.3 103.4 140.1 92.3 63.3 97.0 68.5 54.3 81.8 61.8 35.7 39.4 110.1 118.4 91.9 114.5 305.3 134.9 101.1 42.9 32.5 98.7 59.2 96.7 115.0 145.8 100.7 115.5 88.9 90.5 109.7 125.7 107.7 63.9 75.5 64.2 80.4 78.3 95.1 98.7 44.7 49.0 28.3 47.6 40.2 38.2 42.8 79.4 85.4 19.1 66.2 22.3 4.4 662.9 17.7 33.4 699.2 63.4 126.1 46.6 43.4 282.3 157.5 65.0 50.5 46.0 120.4 638.8 70.4 51.2 591.5 24.6 25.5 29.4 30.6 25.0 27.8 26.3 25.4 26.0 25.7 28.1 33.0 32.8 38.5 135.0 15.3 82.8 51.9 64.8 96.6 52.3 21.4 41.8 41.1 25.3 25.8 110.2 38.6 33.3 29.3 47.9 17.6 74.3 42.9 74.3 18.4 20.8 38.2 21.6 50.5 21.3 28.0 28.2 29.7 38.2 27.3 7.6 31.5 57.8 21.7 207.2 11.8 18.5 40.4 40.7 255.8 76.6 16.4 36.7 183.3 21.4 10.3 245.5 35.5 26.8 19.6 17.5 20.8 27.1 41.0 40.1 35.4 73.2 69.3 45.0 55.6 6.6 26.7 35.4 46.9 11.6 108.0 74.9 20.8 39.1 32.9 70.4 49.7 LTV1 "C6orf93, dJ468K18.4, FLJ14909" ENSG00000135521 "LTV1 ribosome biogenesis factor" Q96GA3 6 143843338-143863812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030159, HPA030160, HPA030161" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA030159: AB_10600770, HPA030160: AB_10600056, HPA030161: AB_10602001" "unprognostic (2.26e-2)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (5.45e-2)" "unprognostic (1.11e-1)" "unprognostic (1.99e-2)" "prognostic unfavorable (4.95e-5)" "unprognostic (7.09e-2)" "unprognostic (2.16e-1)" "unprognostic (1.55e-2)" "unprognostic (1.26e-1)" "unprognostic (4.70e-2)" "prognostic unfavorable (6.01e-13)" "unprognostic (2.94e-1)" "unprognostic (6.83e-2)" "unprognostic (8.62e-3)" "unprognostic (1.41e-1)" 26.3 22.6 12.2 22.4 13.2 52.5 24.1 13.4 16.3 18.8 12.9 20.3 15.7 22.2 15.6 23.3 19.4 12.4 18.7 12.6 13.7 18.5 24.6 19.0 26.2 13.0 12.9 21.2 23.5 14.1 14.0 19.6 13.0 17.5 20.5 10.3 18.0 17.4 36.9 29.3 20.0 21.0 12.6 22.2 20.6 20.7 13.5 16.8 17.0 18.5 25.6 23.1 19.4 14.7 42.5 39.0 45.3 101.4 32.9 39.7 52.5 64.5 47.2 69.7 55.2 63.6 21.6 88.7 50.6 58.7 76.5 46.8 76.3 63.2 96.8 51.2 74.4 175.8 45.1 98.4 57.9 219.0 97.8 45.1 45.5 77.7 84.4 28.7 49.0 51.1 170.3 57.2 54.4 71.7 75.2 92.8 53.6 48.5 42.5 64.1 85.6 40.1 51.9 58.1 40.0 48.2 65.8 53.8 62.3 41.1 30.2 138.1 44.7 44.4 51.6 100.0 120.0 70.9 93.6 118.9 44.5 112.3 63.8 2.0 16.7 7.3 18.9 21.8 20.6 28.6 19.6 20.5 25.3 24.5 21.5 24.9 0.5 36.0 19.5 30.7 18.7 14.2 12.2 13.2 13.4 16.3 12.6 13.7 13.0 12.9 13.0 12.6 13.5 14.7 19.8 6.4 34.1 9.1 22.1 25.6 22.3 28.8 13.1 9.9 10.8 15.7 25.6 10.0 28.3 7.3 2.1 25.5 22.1 9.0 13.7 29.4 25.0 11.5 29.0 20.6 19.7 18.3 13.7 28.7 30.5 27.6 12.8 14.0 24.7 17.6 11.4 18.0 27.9 11.8 14.2 13.3 38.7 13.1 14.8 10.7 25.7 17.0 5.4 10.3 33.6 9.9 23.7 13.6 13.7 29.9 10.4 27.4 17.6 21.9 6.9 17.3 24.1 10.2 6.6 29.0 24.5 57.5 62.5 18.9 32.1 16.3 16.2 57.8 19.7 16.3 MAD2L1BP "CMT2, dJ261G23.1, KIAA0110" ENSG00000124688 "MAD2L1 binding protein" Q15013 6 43629540-43640941 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028729 Supported "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA028729: AB_2672752" "unprognostic (2.60e-1)" "unprognostic (2.06e-1)" "unprognostic (3.92e-2)" "unprognostic (6.97e-2)" "unprognostic (6.91e-2)" "unprognostic (6.92e-2)" "unprognostic (5.74e-3)" "unprognostic (2.67e-3)" "unprognostic (3.60e-1)" "unprognostic (7.18e-2)" "unprognostic (1.71e-1)" "unprognostic (6.64e-2)" "unprognostic (4.61e-2)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-1)" "unprognostic (3.25e-3)" 13.3 16.2 13.6 14.1 13.8 53.5 17.3 14.1 15.8 14.6 15.4 25.9 23.6 12.4 17.3 17.6 16.7 14.4 25.4 14.3 14.9 17.5 21.9 14.9 21.7 13.8 13.2 13.0 16.7 21.1 12.6 14.0 14.2 14.4 27.7 15.2 22.8 13.5 28.5 13.2 18.8 14.5 13.6 17.4 19.3 20.4 14.3 29.3 15.6 44.6 26.6 21.4 10.6 13.8 53.9 24.4 37.7 42.2 32.1 34.7 22.7 31.7 50.9 68.5 63.8 50.3 21.4 41.6 17.6 37.3 62.2 34.4 59.2 43.9 52.6 38.5 46.0 51.5 26.1 43.8 34.6 30.6 29.9 35.3 53.0 51.1 31.0 34.5 52.2 32.8 67.2 21.8 48.4 50.6 27.4 56.5 23.3 221.1 31.3 31.3 29.3 39.4 48.9 42.5 44.7 45.3 22.8 34.5 152.2 28.6 40.6 80.3 28.7 36.5 30.7 24.4 51.3 27.7 25.8 99.0 33.2 51.3 41.0 105.4 41.4 49.4 46.3 42.8 46.5 52.6 54.7 51.4 52.7 47.9 56.5 51.2 35.2 55.6 41.3 34.9 78.9 43.6 13.6 13.8 14.1 15.8 14.3 14.9 13.8 13.2 14.2 13.6 14.3 13.8 11.6 25.6 12.7 3.3 18.2 14.4 20.5 44.9 17.6 12.8 11.6 9.3 10.8 15.7 32.5 3.7 12.5 21.1 11.1 30.7 27.4 28.0 47.0 13.2 8.6 12.5 17.4 20.6 3.0 21.2 21.5 12.0 14.3 10.8 31.6 7.8 11.4 12.7 17.6 10.1 3.2 17.1 32.6 10.4 8.6 36.5 12.2 19.6 28.4 1.9 17.3 13.9 11.3 3.0 5.0 24.7 29.5 12.0 11.1 11.5 28.2 21.2 21.1 15.1 26.3 8.3 13.4 26.4 18.3 12.6 9.7 6.2 14.8 11.9 23.4 27.2 MAGOH "MAGOH1, MAGOHA" ENSG00000162385 "Mago homolog, exon junction complex subunit" P61326 1 53226900-53238518 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015425, HPA043036, HPA047754" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB015425: AB_629914, HPA043036: AB_2678279, HPA047754: AB_2680148" "prognostic favorable (1.85e-4)" "unprognostic (2.61e-2)" "unprognostic (5.39e-2)" "unprognostic (2.33e-1)" "unprognostic (3.59e-1)" "unprognostic (6.34e-3)" "unprognostic (3.07e-3)" "unprognostic (2.18e-1)" "unprognostic (5.17e-2)" "unprognostic (1.46e-2)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (2.01e-2)" "unprognostic (1.63e-1)" "unprognostic (3.60e-2)" "unprognostic (6.75e-3)" 51.4 48.5 36.5 59.0 36.5 141.1 51.8 37.8 47.1 41.0 38.4 61.2 53.1 57.2 59.0 48.1 55.9 37.9 43.3 36.6 38.1 53.6 76.4 44.8 85.0 37.5 37.1 49.2 43.8 50.4 34.9 67.9 37.9 39.9 55.5 34.4 44.5 37.4 43.8 42.9 55.2 50.7 37.5 55.2 46.8 32.3 36.8 101.7 51.7 42.5 86.3 62.1 38.9 38.1 207.8 101.0 169.4 150.2 88.1 56.9 197.6 152.3 92.0 202.4 204.5 233.2 97.1 293.5 168.8 93.1 248.4 125.9 228.3 136.7 242.3 197.1 249.6 266.1 127.4 253.3 141.4 459.3 143.3 62.7 95.3 184.4 150.6 77.7 136.8 260.8 279.6 63.8 109.9 169.3 377.2 316.0 310.0 171.1 218.4 256.1 323.2 154.5 109.1 208.3 142.7 115.7 202.0 161.2 250.1 206.8 85.1 330.2 122.0 122.6 167.7 170.7 354.9 93.6 184.8 453.4 109.4 289.5 127.0 31.5 34.8 53.9 49.3 51.9 48.1 47.4 46.9 51.5 50.0 42.9 42.6 44.9 41.9 52.9 50.2 58.6 54.2 32.7 36.5 36.5 37.8 47.1 36.6 38.1 37.5 37.1 37.9 37.5 36.8 38.1 134.5 51.3 47.6 10.1 93.5 144.4 121.3 231.6 99.0 31.0 62.1 85.9 50.6 60.1 106.9 57.0 14.6 206.9 123.5 47.0 178.1 96.2 44.9 123.9 83.7 89.6 54.4 90.9 13.0 84.9 195.4 83.5 46.9 102.2 83.6 78.4 57.8 44.2 116.0 23.5 12.4 89.2 130.2 47.8 103.2 16.1 75.5 80.0 81.8 7.5 102.5 67.2 84.5 10.6 15.1 87.4 70.9 68.1 62.6 92.3 69.0 152.0 100.4 36.4 59.2 93.9 148.1 90.0 67.9 82.7 120.8 241.9 107.6 89.5 87.1 92.1 MAPK1IP1L C14orf32 ENSG00000168175 "Mitogen-activated protein kinase 1 interacting protein 1 like" Q8NDC0 14 55051647-55070194 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034506 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA034506: AB_10669784" "unprognostic (3.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.83e-1)" "unprognostic (2.68e-2)" "unprognostic (1.43e-1)" "unprognostic (1.28e-1)" "unprognostic (6.86e-3)" "unprognostic (8.17e-3)" "unprognostic (3.32e-1)" "unprognostic (2.91e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "prognostic favorable (4.82e-5)" "unprognostic (7.96e-2)" "unprognostic (1.71e-1)" "unprognostic (2.45e-1)" "unprognostic (5.40e-2)" 31.2 26.3 15.6 27.5 16.5 83.2 26.5 16.7 22.3 26.0 15.4 24.4 18.9 30.2 29.4 27.6 28.9 26.4 33.3 16.0 19.6 42.0 27.3 25.7 29.5 18.0 17.8 34.6 21.9 23.4 22.3 30.2 17.5 24.6 24.8 19.1 30.2 24.6 25.7 27.0 21.2 35.6 17.0 24.2 23.1 21.6 18.0 23.9 25.8 19.9 36.5 34.2 21.8 18.1 49.0 42.3 73.1 46.8 57.8 56.6 56.5 53.7 56.8 65.2 75.2 34.1 42.2 56.3 44.4 72.0 39.2 52.5 79.3 81.3 90.7 51.4 50.6 54.3 39.4 51.7 63.0 67.3 57.4 73.6 60.0 54.5 85.9 47.5 87.9 35.4 51.2 48.7 95.6 59.0 56.9 51.7 53.1 46.2 70.4 48.1 80.4 34.0 89.9 54.1 47.5 55.0 51.9 36.7 51.6 65.1 65.5 38.4 66.8 66.6 87.0 41.7 48.6 29.9 46.3 73.3 53.3 34.7 49.0 44.1 26.7 32.1 24.2 37.4 32.0 31.8 28.3 26.3 29.0 27.4 26.0 26.1 19.7 26.0 36.4 37.2 37.9 25.1 15.6 16.5 16.7 22.3 16.0 19.6 18.0 17.8 17.5 17.0 18.0 18.1 73.5 70.5 66.9 25.5 106.3 71.9 164.0 77.3 53.5 22.9 44.1 36.2 71.2 40.0 66.3 47.8 37.5 121.2 78.0 60.3 70.5 65.0 28.5 73.7 57.1 69.5 57.9 57.7 34.3 69.4 112.3 60.7 70.3 86.2 83.1 41.5 43.2 51.5 75.1 38.7 32.2 54.8 50.8 64.4 88.4 14.1 51.3 72.9 49.8 28.1 65.0 60.0 49.4 27.2 38.1 94.4 44.2 54.2 109.5 104.8 44.1 103.4 39.6 24.9 32.9 59.1 66.5 81.1 60.6 53.6 71.6 151.3 86.4 40.5 46.9 145.3 MAPRE1 EB1 ENSG00000101367 "Microtubule associated protein RP/EB family member 1" Q15691 20 32819954-32850405 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003600, CAB009337, CAB019391" Supported Enhanced "Centriolar satellite,Cytosol" NA NA 11000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009337: AB_2141629, CAB019391: , HPA003600: AB_1079309" "unprognostic (3.74e-1)" "unprognostic (1.89e-1)" "unprognostic (2.68e-1)" "unprognostic (4.48e-3)" "unprognostic (2.98e-3)" "unprognostic (1.10e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.25e-2)" "unprognostic (1.17e-1)" "unprognostic (7.24e-2)" "unprognostic (5.99e-2)" "unprognostic (6.05e-2)" "unprognostic (3.76e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (5.42e-2)" "unprognostic (4.59e-3)" 66.7 44.5 41.2 69.7 46.7 192.7 48.3 45.3 45.5 45.9 41.9 69.0 39.7 61.0 52.9 62.7 44.8 57.4 58.2 37.0 50.0 54.1 30.4 50.6 75.8 48.0 52.5 37.8 40.4 38.3 24.3 66.8 47.9 56.0 58.0 16.1 32.7 70.6 34.1 34.7 41.2 91.3 47.7 57.7 43.9 54.4 47.5 88.0 74.1 39.7 69.3 83.1 37.8 47.0 179.7 161.4 176.6 102.0 93.5 84.3 250.7 171.3 106.3 261.0 191.0 470.0 161.9 271.2 167.4 154.8 265.6 159.9 213.1 191.6 283.7 92.4 83.1 523.3 105.0 253.2 98.7 190.6 222.8 91.6 94.1 213.8 141.7 89.3 165.0 151.4 240.0 150.6 232.4 111.0 263.0 166.2 127.6 182.7 147.5 174.4 312.8 145.9 143.0 121.8 109.7 115.3 307.2 134.3 179.4 160.6 194.3 140.0 147.5 291.9 157.7 147.3 224.7 131.5 194.5 289.6 154.9 428.3 166.0 256.8 125.8 262.1 100.1 150.8 104.0 75.1 94.1 92.9 97.4 81.8 94.6 104.3 139.7 111.1 170.6 89.5 107.1 185.6 41.2 46.7 45.3 45.5 37.0 50.0 48.0 52.5 47.9 47.7 47.5 47.0 71.6 19.2 30.2 8.1 67.0 132.8 194.4 48.1 62.0 11.1 54.7 42.3 36.5 25.8 44.5 55.2 8.4 108.0 82.0 67.6 84.1 68.8 90.2 43.5 44.7 64.8 71.5 52.8 7.8 78.3 130.0 61.4 40.8 60.9 115.4 45.7 39.3 14.9 107.0 10.1 8.5 43.6 36.7 94.6 121.2 76.6 35.8 99.5 71.2 12.2 120.5 36.5 92.7 7.5 12.6 75.0 40.5 64.3 71.1 115.3 32.6 74.3 39.4 11.5 65.7 61.5 102.8 72.1 62.1 65.2 110.8 169.2 89.8 76.6 44.4 123.1 MARCHF8 "c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favorable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favorable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 14.3 19.2 11.8 12.4 18.5 49.1 16.8 19.3 13.1 13.8 11.7 21.3 14.2 14.4 10.4 10.6 15.3 13.4 20.5 11.1 13.1 15.5 16.9 15.0 16.9 18.8 14.2 19.5 26.5 19.8 16.0 12.2 17.3 11.5 18.3 18.2 14.8 15.2 14.7 10.5 22.4 13.8 14.7 18.7 14.4 57.1 16.1 17.8 16.3 15.4 20.3 11.4 9.0 26.7 16.6 16.4 13.7 12.4 19.4 24.2 10.1 7.5 35.0 13.6 14.8 4.2 16.8 23.8 12.6 21.9 12.3 3.0 15.2 12.4 12.6 36.3 16.7 9.2 7.4 10.0 13.6 11.3 39.1 19.8 16.3 6.8 17.9 13.4 22.5 22.4 26.5 23.2 10.5 5.8 11.5 7.1 4.5 2.4 5.3 12.7 13.7 7.0 10.2 9.5 12.2 17.0 14.7 3.5 14.0 13.3 21.2 5.2 15.1 10.6 13.6 15.6 12.0 39.8 34.2 10.5 21.0 15.5 2.9 13.9 1.1 10.8 3.0 1.9 4.5 3.5 3.4 3.3 1.6 5.4 2.5 3.2 14.1 8.5 0.9 1.6 3.6 2.5 11.8 18.5 19.3 13.1 11.1 13.1 18.8 14.2 17.3 14.7 16.1 26.7 6.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 2.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.0 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 5.0 3.9 1.7 6.2 1.9 18.7 5.3 2.3 2.3 3.8 2.1 4.1 4.4 3.9 4.5 5.9 3.0 3.9 2.5 1.9 2.0 3.9 4.9 4.0 8.9 2.0 2.0 3.4 3.3 6.0 3.1 6.5 2.1 3.1 5.2 2.7 4.1 3.0 2.3 6.0 4.3 4.5 1.6 4.6 4.7 6.5 2.0 10.4 4.7 2.2 7.1 4.5 4.3 2.3 29.4 22.0 43.8 15.5 6.2 9.1 25.4 43.3 18.0 68.4 83.8 26.7 27.2 22.4 16.1 18.4 33.5 26.8 27.9 16.0 48.2 20.2 26.5 26.9 14.5 15.5 3.8 10.4 19.8 5.6 7.5 41.6 7.9 9.0 14.7 18.2 21.1 49.9 41.5 17.9 34.8 11.2 32.0 15.9 8.9 22.2 71.9 18.9 17.4 10.6 19.2 26.8 26.0 17.6 19.1 28.1 17.2 21.4 12.6 17.0 36.3 44.0 37.4 5.9 10.3 34.7 18.3 31.1 14.8 0.2 1.8 1.7 0.7 1.7 1.1 1.1 0.9 0.7 1.0 1.6 0.9 0.8 2.3 1.0 1.8 1.1 1.6 0.8 1.7 1.9 2.3 2.3 1.9 2.0 2.0 2.0 2.1 1.6 2.0 2.3 4.3 6.4 7.8 2.6 7.4 11.0 4.9 4.4 4.0 1.7 4.2 4.8 3.0 2.8 7.0 1.8 0.0 8.6 10.1 7.0 0.0 4.0 3.0 9.7 5.3 4.6 4.2 7.8 4.3 2.5 24.9 7.3 6.1 17.9 12.7 6.9 2.5 2.5 5.8 3.3 4.3 3.7 4.1 7.8 19.3 1.7 3.1 11.3 0.0 3.7 5.1 1.8 3.1 3.5 4.9 4.4 2.9 2.6 7.1 5.0 2.8 1.9 4.0 1.0 0.0 3.8 5.3 14.9 14.1 10.9 9.9 6.2 11.6 5.4 4.5 6.6 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MED30 "THRAP6, TRAP25" ENSG00000164758 "Mediator complex subunit 30" Q96HR3 8 117520713-117540262 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 169.9;Suprabasal keratinocytes: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045767 Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA045767: AB_2679446" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (3.86e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-1)" "unprognostic (3.20e-2)" "unprognostic (2.00e-2)" "unprognostic (3.33e-2)" "unprognostic (8.41e-2)" "unprognostic (4.02e-2)" "unprognostic (1.51e-2)" "unprognostic (7.73e-2)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.38e-3)" "unprognostic (2.80e-1)" "unprognostic (1.05e-1)" "unprognostic (4.62e-2)" 18.4 9.4 10.7 11.6 11.4 44.6 17.6 11.4 14.4 15.5 10.1 14.6 9.3 15.7 8.3 12.6 18.4 6.6 11.0 10.4 10.6 8.2 15.2 13.0 17.3 11.1 10.8 20.1 9.1 7.3 10.0 11.4 11.1 11.4 11.6 5.0 9.7 10.3 10.4 17.0 12.4 9.3 11.5 14.0 11.2 11.4 10.9 25.1 12.1 10.4 15.3 13.3 14.9 12.7 54.0 5.6 20.8 13.9 14.2 13.3 22.9 15.9 16.9 23.8 29.4 10.2 26.2 42.7 24.7 8.7 18.3 23.7 18.6 12.4 30.4 57.4 23.0 34.7 3.2 13.2 15.6 27.7 28.9 12.3 13.8 12.3 27.5 8.8 14.9 60.7 19.7 25.2 11.4 12.7 85.9 70.9 11.6 50.6 38.7 31.5 26.1 19.1 12.2 9.3 29.2 24.7 18.8 42.6 25.6 18.8 10.3 35.1 7.1 11.5 30.2 21.2 28.0 22.0 16.1 50.1 10.7 31.2 19.7 64.0 37.9 111.3 46.7 46.2 49.7 56.3 46.8 46.7 42.8 63.6 51.8 49.4 90.7 44.5 69.9 82.5 55.6 43.4 10.7 11.4 11.4 14.4 10.4 10.6 11.1 10.8 11.1 11.5 10.9 12.7 47.6 9.6 21.7 9.1 71.4 169.9 81.2 65.2 52.9 6.0 33.7 46.6 5.5 25.8 32.2 9.2 6.2 45.3 62.8 27.9 11.7 22.6 32.7 49.5 38.0 33.2 37.7 35.7 10.0 22.7 69.4 46.9 15.8 42.0 21.5 15.7 30.0 21.9 30.4 0.0 12.7 43.4 42.7 28.8 65.4 11.9 59.7 37.7 40.9 6.5 23.5 10.4 43.3 9.0 18.4 20.5 34.4 37.2 37.5 76.5 24.2 16.9 64.8 5.3 32.9 68.4 44.6 47.8 37.1 46.4 152.3 61.6 60.4 13.5 35.5 72.1 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0" "Cell type enhanced" "Detected in many" "Microglial cells: 175.2;Proximal enterocytes: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 127.2;HUVEC TERT2: 48.3;JURKAT: 86.5;TIME: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 11.2 7.8 13.2 20.8 17.8 96.0 12.5 26.1 15.6 8.9 15.1 24.4 29.5 5.8 3.7 6.3 7.0 12.7 7.6 13.1 15.2 27.5 9.7 16.9 21.1 16.4 15.8 3.2 38.8 28.0 9.8 19.6 15.5 7.5 25.5 5.4 25.9 6.4 3.8 4.1 43.8 11.5 18.1 8.1 11.3 6.3 15.5 20.5 8.7 4.7 18.2 13.1 4.7 22.9 8.8 1.7 3.4 7.3 0.0 0.0 127.2 0.0 0.1 0.9 0.0 21.0 10.6 0.0 18.9 0.0 2.4 0.4 7.2 1.0 0.2 10.6 7.9 0.5 0.0 36.7 0.2 17.8 6.4 0.0 4.7 0.0 0.7 0.3 48.3 86.5 1.6 9.2 0.0 17.3 39.3 30.9 1.1 7.6 1.4 9.8 0.0 10.5 24.8 17.6 10.4 3.3 2.5 32.2 4.8 9.2 7.6 23.8 78.8 0.0 4.0 0.1 2.6 3.2 7.6 2.2 0.0 26.7 0.6 7.0 5.1 12.7 20.8 1.0 27.5 3.6 25.2 23.7 3.8 2.5 32.6 27.2 14.0 15.3 2.5 17.1 16.0 12.5 13.2 17.8 26.1 15.6 13.1 15.2 16.4 15.8 15.5 18.1 15.5 22.9 80.8 54.5 25.7 19.2 22.7 9.9 21.1 6.1 11.4 19.8 28.2 15.6 13.4 11.5 17.6 22.0 4.2 6.2 116.9 92.4 21.5 20.8 12.7 14.2 3.8 39.8 53.0 6.3 58.0 29.8 77.9 7.2 19.4 35.1 13.3 5.1 18.9 10.4 57.2 48.8 48.6 41.3 34.6 33.9 18.3 17.5 2.5 54.5 10.6 175.2 21.0 13.4 89.6 36.7 42.0 21.6 58.2 2.2 31.4 17.8 132.4 27.3 7.1 4.8 6.6 6.8 4.9 2.5 7.7 8.6 10.5 14.9 112.2 0.7 40.9 30.2 MIS18BP1 "C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1" ENSG00000129534 "MIS18 binding protein 1" Q6P0N0 14 45203190-45253540 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 40.7" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.1;monocytes: 150.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006504 Approved Approved Nucleoli,Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli Cytosol "HPA006504: AB_1078317" "unprognostic (2.12e-1)" "unprognostic (1.06e-1)" "unprognostic (2.58e-2)" "unprognostic (1.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (3.83e-4)" "unprognostic (4.18e-1)" "unprognostic (1.36e-2)" "unprognostic (3.33e-1)" "unprognostic (3.32e-2)" "unprognostic (2.32e-3)" "unprognostic (3.31e-2)" "unprognostic (5.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.97e-1)" "unprognostic (2.21e-1)" 8.6 3.7 1.5 14.1 1.4 40.7 10.7 0.9 1.6 7.3 1.1 8.0 8.4 10.2 5.3 7.1 6.7 7.7 3.8 1.4 1.7 3.7 4.1 9.5 23.2 2.1 1.9 12.2 4.6 2.3 1.3 10.6 2.4 6.3 10.1 1.2 6.7 5.8 1.3 8.6 9.6 9.6 1.9 15.2 8.5 13.5 1.5 24.4 6.8 3.8 21.7 7.8 3.9 2.8 54.1 20.0 40.7 18.0 12.1 17.2 30.0 36.4 19.2 29.7 36.5 10.7 50.7 73.6 15.5 18.5 12.8 37.0 23.9 18.5 55.3 39.5 15.3 44.5 23.2 13.8 8.1 103.7 39.7 12.5 7.4 17.6 16.5 19.4 36.7 14.1 19.7 17.2 29.1 19.9 44.1 45.9 30.8 26.5 24.9 51.5 16.4 28.5 15.3 22.3 28.4 12.3 16.2 24.6 13.1 24.1 29.5 58.1 20.4 15.7 47.4 19.5 16.6 15.3 21.5 34.5 8.8 42.6 22.8 64.5 28.8 35.8 7.9 28.5 8.5 28.5 7.5 6.8 21.5 25.5 5.0 5.1 17.8 10.8 53.8 31.0 10.9 9.1 1.5 1.4 0.9 1.6 1.4 1.7 2.1 1.9 2.4 1.9 1.5 2.8 54.6 25.6 27.8 6.8 87.7 20.1 11.6 17.7 19.4 8.4 24.3 27.3 13.3 7.2 26.1 9.2 16.7 40.9 91.6 17.1 5.9 14.0 3.5 29.2 47.6 43.5 27.6 72.6 34.5 11.1 42.5 32.5 35.7 28.0 43.6 145.1 30.4 7.3 35.4 0.0 7.6 25.8 18.3 89.8 30.9 6.8 55.3 115.7 5.4 74.0 150.1 5.1 55.6 9.5 11.1 13.5 47.7 60.5 73.5 25.0 12.1 5.0 20.9 7.6 0.0 13.9 23.3 80.0 105.4 32.5 26.3 19.4 54.5 77.9 29.9 24.6 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MOB4 "2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3" ENSG00000115540 "MOB family member 4, phocein" Q9Y3A3 2 197515571-197553699 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 367.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034082, HPA044125" Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB034082: AB_1127220, HPA044125: AB_2678822" "unprognostic (4.60e-2)" "unprognostic (3.23e-1)" "unprognostic (2.16e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.23e-1)" "unprognostic (4.88e-2)" "unprognostic (1.72e-1)" "unprognostic (8.03e-2)" "unprognostic (8.44e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (3.35e-1)" "unprognostic (8.36e-2)" "unprognostic (3.30e-2)" "unprognostic (3.07e-2)" 22.1 88.5 16.4 18.1 17.1 64.8 28.5 20.6 25.2 23.1 13.0 25.0 18.4 27.5 23.8 42.9 18.8 22.1 41.1 17.5 18.2 21.9 21.5 20.1 23.7 15.4 16.7 23.6 17.8 28.7 11.9 32.3 16.2 28.2 26.5 13.9 19.4 22.2 36.1 21.1 20.6 32.4 17.9 19.1 19.0 10.9 17.5 23.8 24.6 36.9 28.7 31.0 19.4 19.0 51.6 27.1 68.2 26.1 54.3 51.3 63.9 57.3 57.1 77.5 64.2 64.8 39.5 46.5 52.4 65.2 54.6 30.2 56.0 57.5 92.2 36.8 41.1 61.4 46.8 62.6 49.5 50.6 50.2 51.1 40.1 52.8 37.7 49.3 53.6 34.5 33.3 28.1 75.0 57.0 31.6 84.2 62.7 51.5 63.8 32.6 55.4 36.2 72.8 84.5 33.3 46.0 42.0 58.5 54.9 89.2 38.6 55.0 46.1 54.6 27.5 58.3 60.6 30.0 43.9 58.7 44.8 35.2 56.6 24.8 9.2 18.2 9.7 11.7 12.1 12.8 10.9 13.0 11.4 10.9 12.9 14.0 22.8 14.7 12.3 10.5 16.9 10.8 16.4 17.1 20.6 25.2 17.5 18.2 15.4 16.7 16.2 17.9 17.5 19.0 53.6 28.9 26.1 0.0 70.5 77.5 50.8 107.0 56.9 39.8 38.3 36.4 54.3 32.9 60.2 20.2 10.4 145.8 77.9 45.3 88.0 64.3 1.7 23.3 28.2 54.1 34.0 31.5 0.0 50.4 101.6 49.5 32.6 23.4 41.3 18.8 40.0 25.9 57.8 47.1 0.0 48.3 97.6 33.7 98.6 4.6 42.6 42.3 58.7 0.0 50.8 56.2 54.6 0.0 0.0 66.4 35.7 38.4 61.7 54.4 34.2 66.7 44.4 32.5 52.6 39.3 74.8 54.3 43.3 54.7 83.5 367.4 82.9 58.5 36.6 65.7 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MTMR14 "C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy" ENSG00000163719 "Myotubularin related protein 14" Q8NCE2 3 9649433-9702393 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054063 Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "HPA054063: AB_2682365" "unprognostic (9.50e-2)" "unprognostic (5.60e-3)" "unprognostic (9.28e-2)" "unprognostic (1.31e-1)" "unprognostic (8.81e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.74e-4)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-3)" 18.3 18.0 15.7 22.1 16.4 56.0 15.5 15.6 15.7 12.4 28.1 18.5 17.7 12.7 11.2 15.9 13.5 13.4 34.4 14.8 16.3 18.4 19.5 21.6 37.3 16.4 16.0 13.9 11.8 14.9 10.2 20.1 16.8 12.1 18.4 9.2 13.9 10.7 45.3 19.8 17.9 13.4 15.9 27.8 16.5 16.9 16.6 24.4 15.3 35.6 41.6 18.3 12.7 18.8 18.9 29.1 19.1 11.1 25.6 17.1 106.4 15.0 28.6 29.3 33.6 22.1 27.7 38.2 16.0 24.2 37.8 11.3 23.4 34.2 24.7 34.5 32.5 40.0 24.4 31.9 45.6 35.3 70.6 31.9 22.9 36.9 38.4 19.9 33.2 28.6 25.0 34.0 20.5 60.4 26.1 28.9 31.3 28.2 23.8 27.0 23.1 41.1 26.4 32.6 10.2 28.7 16.7 21.6 29.3 26.0 28.9 57.3 26.0 13.7 21.5 24.9 21.5 37.0 63.3 49.6 31.0 44.0 18.2 116.9 139.9 107.1 44.7 148.1 44.5 76.5 43.3 45.5 177.8 63.4 39.6 40.6 87.7 58.0 145.1 97.2 55.5 113.7 15.7 16.4 15.6 15.7 14.8 16.3 16.4 16.0 16.8 15.9 16.6 18.8 19.3 16.0 6.4 21.5 41.7 10.8 12.2 22.6 8.0 0.0 13.2 12.1 23.8 18.6 14.8 9.2 0.0 47.6 34.2 22.0 29.4 38.3 13.8 10.4 10.5 20.0 12.5 24.8 12.2 28.2 39.0 13.0 27.0 19.6 19.7 15.0 26.4 16.7 67.7 0.0 10.3 14.6 22.4 65.3 28.3 12.8 13.1 55.8 12.4 28.1 68.4 0.0 22.6 9.5 19.9 41.9 25.9 13.2 25.0 15.2 33.2 37.3 10.1 0.0 6.6 15.2 14.0 39.0 40.0 14.7 18.0 64.7 27.0 40.5 16.8 12.7 MTPAP "FLJ10486, PAPD1, SPAX4, TENT6" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.8" "Cell type enriched" "Detected in many" 7 "Early spermatids: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA038620: AB_10673015, HPA058232: AB_2683646" "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" 8.9 7.4 4.9 10.3 4.8 36.8 9.7 12.6 6.7 6.1 3.1 9.6 10.6 9.0 6.2 8.3 6.6 5.2 8.8 4.8 4.3 9.6 10.6 6.3 10.7 3.4 3.5 8.2 10.0 8.4 2.7 9.6 3.9 7.2 11.0 7.1 8.0 4.9 13.2 8.4 9.0 9.1 3.2 9.3 7.1 5.1 3.6 9.2 10.2 12.0 10.3 8.1 5.2 6.2 26.0 25.3 15.8 23.0 15.2 14.2 20.6 17.6 6.2 17.7 18.4 27.0 35.4 36.9 12.3 11.7 16.3 29.7 31.1 20.7 21.6 18.7 24.0 37.3 23.7 27.5 16.0 24.6 28.2 14.3 19.0 19.9 11.7 9.8 19.6 34.0 41.2 28.1 13.5 21.8 29.8 21.8 10.8 19.5 13.3 29.6 27.9 34.4 16.2 17.1 25.9 20.8 16.0 16.4 24.7 14.8 15.8 15.6 18.7 18.4 23.8 26.0 19.8 6.2 16.3 50.8 15.9 44.5 6.6 27.4 25.2 27.3 21.7 35.0 23.0 20.8 20.4 21.1 33.0 17.1 21.6 22.0 4.2 25.1 27.9 17.3 23.1 13.1 4.9 4.8 12.6 6.7 4.8 4.3 3.4 3.5 3.9 3.2 3.6 6.2 12.2 9.6 7.4 9.1 11.2 25.2 13.9 7.4 4.6 0.0 9.8 9.8 16.7 15.7 9.2 3.7 0.0 13.1 13.9 8.1 19.6 9.6 240.7 9.9 14.8 12.9 4.2 16.6 12.7 9.1 12.0 12.7 7.7 12.5 5.1 18.8 12.5 14.6 14.7 0.0 14.5 15.6 6.1 15.8 13.6 34.3 12.2 10.8 8.8 8.4 14.8 0.0 5.2 4.5 14.4 8.9 5.2 16.6 5.3 14.1 8.7 14.2 8.6 0.0 13.1 14.7 10.8 25.3 19.5 11.4 24.9 11.5 8.8 12.6 18.4 16.6 MTPN "GCDP, MYOTROPHIN, V-1" ENSG00000105887 Myotrophin P58546 7 135926760-135977359 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019735 Approved Approved "Plasma membrane,Cytosol" NA NA 14000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA019735: AB_1858710" "unprognostic (5.97e-2)" "unprognostic (2.53e-2)" "unprognostic (8.52e-2)" "unprognostic (3.62e-3)" "unprognostic (2.20e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.06e-3)" "unprognostic (3.30e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (4.50e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (2.43e-1)" "unprognostic (9.00e-3)" "unprognostic (4.86e-3)" 68.9 49.5 66.7 65.1 75.5 151.1 50.7 41.6 79.4 67.1 45.6 50.5 40.2 65.1 50.9 125.5 62.2 50.5 77.1 79.5 65.0 58.5 49.7 57.8 89.4 77.7 60.0 49.2 23.8 75.9 34.0 61.7 54.0 52.9 55.4 39.9 36.8 51.3 47.6 46.8 46.6 66.1 56.3 79.7 41.2 56.6 65.2 72.5 88.2 48.0 107.8 67.2 58.5 53.3 126.0 90.6 111.5 170.4 160.3 187.2 55.8 189.5 208.0 129.3 137.7 104.5 139.4 229.7 132.7 255.6 188.6 78.9 107.1 161.1 246.1 153.1 84.2 152.9 94.6 77.2 127.3 211.5 213.5 136.5 158.5 152.9 147.7 180.1 205.5 163.6 182.3 138.1 253.2 94.3 208.4 163.0 155.9 121.9 118.9 120.0 83.8 187.7 144.5 103.1 140.6 248.3 157.1 105.8 158.4 102.8 75.4 130.7 215.2 193.5 85.0 192.3 189.7 103.8 160.2 325.9 307.5 185.0 420.2 117.4 75.4 85.2 54.7 105.7 46.0 107.9 33.5 41.7 89.3 125.0 21.5 31.7 180.3 46.0 169.4 82.8 32.6 70.5 66.7 75.5 41.6 79.4 79.5 65.0 77.7 60.0 54.0 56.3 65.2 53.3 110.6 48.1 40.6 0.0 149.8 119.2 58.9 86.8 72.8 0.0 68.6 72.8 82.0 70.1 61.9 69.9 0.0 63.4 131.6 67.1 90.1 69.6 77.8 83.8 153.3 108.5 33.0 91.9 0.0 51.3 73.1 92.4 45.9 131.9 98.6 64.8 87.4 59.2 100.5 0.0 0.0 46.9 46.8 247.5 232.7 28.6 86.3 214.0 101.4 0.0 234.2 0.0 125.7 0.0 0.0 99.9 67.0 123.8 59.2 96.2 52.6 88.3 50.0 0.0 92.1 99.8 79.8 65.8 123.8 143.3 149.0 68.8 86.1 106.5 52.4 106.9 MXD1 "bHLHc58, MAD, MAD1" ENSG00000059728 "MAX dimerization protein 1" Q05195 2 69897688-69942945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 173.4;esophagus: 130.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 507.0;Langerhans cells: 224.8;Paneth cells: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 496.3" "Lineage enriched" "Detected in all" 49 "granulocytes: 496.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001599 Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA001599: AB_1079434" "unprognostic (1.59e-1)" "unprognostic (5.11e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (8.14e-6)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-3)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.50e-4)" "unprognostic (8.72e-2)" "unprognostic (3.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.56e-3)" "unprognostic (1.77e-2)" 13.5 3.6 6.2 40.4 6.9 173.4 7.0 10.0 15.8 35.2 6.4 30.3 28.8 5.4 1.9 130.0 8.1 9.4 8.3 6.5 7.8 6.8 11.3 36.5 3.9 7.1 6.3 6.1 4.6 6.8 6.7 10.9 8.1 5.5 28.9 15.6 17.4 2.0 6.0 12.8 43.7 9.1 5.4 32.8 16.9 6.3 10.7 13.9 7.5 6.5 15.1 17.4 50.6 10.5 5.0 2.1 3.0 2.2 6.5 3.2 11.2 5.5 3.1 2.6 1.9 6.8 3.8 2.8 2.8 2.1 2.5 17.3 5.8 10.7 2.7 1.6 6.9 5.9 6.6 7.0 21.9 7.3 5.7 3.7 17.8 5.9 27.0 3.2 3.4 2.8 10.4 10.9 1.6 4.0 3.4 14.1 0.8 7.3 3.5 1.6 3.1 7.1 3.4 5.8 9.8 4.1 7.3 9.3 3.9 3.4 1.4 4.1 13.2 3.7 1.0 4.1 5.2 7.5 13.7 1.1 3.8 12.5 1.4 124.0 10.2 105.7 2.3 6.4 2.5 1.1 1.6 1.7 5.2 1.3 1.8 1.9 496.3 2.8 5.5 1.6 1.5 4.5 6.2 6.9 10.0 15.8 6.5 7.8 7.1 6.3 8.1 5.4 10.7 10.5 18.0 38.5 23.7 16.0 25.4 25.7 31.6 61.8 21.6 29.8 51.6 29.3 6.9 10.0 44.7 1.8 54.2 10.1 46.2 507.0 7.9 12.9 17.0 34.3 17.5 12.0 97.5 17.7 23.6 16.5 8.0 17.9 110.1 81.6 27.3 3.0 5.7 6.8 28.6 10.1 20.2 155.5 71.2 56.5 224.8 17.8 4.7 190.8 16.0 11.2 40.7 62.1 18.6 20.1 21.7 70.1 369.6 2.6 33.1 43.3 178.8 6.9 24.2 21.7 0.0 14.7 18.3 19.9 2.7 88.2 56.4 105.9 30.3 5.2 65.9 126.7 NAA16 "FLJ22054, MGC40612, NARG1L, PRO2435" ENSG00000172766 "N-alpha-acetyltransferase 16, NatA auxiliary subunit" Q6N069 13 41311267-41377030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 23.5;pancreas: 20.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039761, HPA040157" Approved Enhanced Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA039761: AB_10795112, HPA040157: AB_10793917" "unprognostic (2.09e-2)" "unprognostic (2.86e-2)" "unprognostic (2.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.66e-2)" "unprognostic (4.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.90e-1)" "unprognostic (3.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.36e-2)" "unprognostic (7.94e-2)" "unprognostic (5.81e-2)" "unprognostic (1.58e-1)" "unprognostic (3.34e-2)" 3.2 2.7 1.8 5.0 2.1 23.5 3.9 4.9 2.2 5.0 1.6 2.8 4.3 6.3 2.7 4.2 4.3 3.5 2.4 1.5 2.4 3.1 2.9 3.7 6.5 1.8 2.0 5.9 20.5 3.5 1.9 3.8 2.0 4.7 3.2 5.9 3.9 3.8 4.4 4.1 4.1 3.7 1.1 4.5 4.8 7.5 2.2 5.9 3.7 4.5 4.0 3.9 3.5 3.4 7.3 6.0 14.9 10.8 5.1 6.5 5.7 8.9 7.4 8.6 7.5 7.1 5.6 12.1 4.1 7.2 3.5 10.0 7.7 5.7 10.5 7.5 15.5 15.0 6.3 7.2 5.5 16.8 9.7 4.5 4.2 3.6 6.8 5.8 8.6 11.7 6.8 6.5 5.6 6.0 17.5 4.8 12.6 10.1 8.1 12.9 6.1 10.1 6.8 6.6 5.0 11.6 8.0 7.7 3.3 8.6 4.7 9.3 6.2 5.8 4.9 9.3 7.0 4.5 5.4 14.0 7.5 7.2 7.1 4.4 1.5 3.1 2.3 0.8 2.1 1.0 2.6 2.4 0.8 1.6 4.5 4.7 0.8 3.4 1.2 1.6 2.0 1.3 1.8 2.1 4.9 2.2 1.5 2.4 1.8 2.0 2.0 1.1 2.2 3.4 15.0 9.6 16.7 34.0 19.6 17.7 21.9 9.5 18.8 27.9 10.3 10.2 12.0 10.0 12.4 9.2 14.6 8.8 20.2 5.6 1.9 12.5 17.9 17.2 26.7 16.7 7.7 15.4 53.5 20.5 7.8 18.8 19.9 22.1 3.8 18.9 13.6 8.7 19.1 38.7 66.9 5.5 4.1 8.5 11.7 26.3 30.1 14.3 14.2 45.0 12.0 11.3 21.6 68.9 57.1 13.1 6.9 19.9 28.3 20.0 7.3 7.0 17.3 33.6 19.7 17.0 24.7 39.2 28.8 17.0 14.6 2.9 31.7 17.1 9.7 21.2 NBPF10 AG1 ENSG00000271425 "NBPF member 10" 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 46.1;Basal keratinocytes: 57.0;Langerhans cells: 100.9;Suprabasal keratinocytes: 105.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" 3.7 1.1 3.4 2.8 2.8 7.6 4.3 2.2 6.4 4.9 7.4 2.8 1.1 3.5 3.8 2.8 3.0 2.2 1.3 3.6 2.2 1.9 3.2 3.3 2.5 3.8 3.1 5.4 3.3 3.2 0.3 2.5 2.9 2.7 2.8 4.6 2.0 3.0 1.0 7.4 1.2 3.4 1.7 4.4 1.8 3.3 4.5 2.7 2.3 2.2 2.4 2.2 1.4 4.1 6.4 1.7 3.6 2.4 11.3 13.6 3.0 3.3 4.5 3.3 3.3 1.5 3.0 2.7 0.7 6.4 3.2 3.0 4.0 4.5 6.7 3.4 3.0 6.3 5.0 0.8 4.5 2.7 1.9 12.4 4.1 9.2 8.8 10.6 3.9 1.7 2.0 8.7 7.1 7.3 1.1 2.4 1.5 1.6 4.7 1.4 2.6 3.6 2.3 4.5 0.4 0.4 5.1 4.9 1.8 5.8 4.2 3.6 12.3 3.2 2.9 2.9 4.4 5.8 2.3 3.4 2.9 2.9 2.7 2.2 2.0 2.7 0.3 1.0 0.4 1.5 0.3 0.3 0.8 1.5 0.3 0.2 5.6 0.3 2.3 2.2 0.3 0.1 3.4 2.8 2.2 6.4 3.6 2.2 3.8 3.1 2.9 1.7 4.5 4.1 0.5 76.9 46.1 13.7 12.8 57.0 4.9 15.4 5.2 0.5 3.7 2.0 8.4 2.8 22.0 0.0 0.0 0.7 9.2 1.5 0.0 5.3 15.1 2.8 2.8 3.4 0.0 10.5 0.8 2.7 5.0 18.2 3.1 6.1 20.2 6.4 0.7 1.8 1.4 0.0 1.1 2.7 14.2 5.0 100.9 3.3 6.5 17.7 30.2 4.7 14.2 2.0 9.2 5.0 0.1 5.5 25.3 8.2 5.7 2.1 2.2 0.2 19.6 2.0 0.0 7.6 9.9 9.9 5.4 23.8 105.8 0.5 6.6 1.4 3.4 4.5 NBPF14 DJ328E19.C1.1 ENSG00000270629 "NBPF member 14" 1 148531385-148679742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.8;Astrocytes: 95.0;Paneth cells: 174.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 128.6" "HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Microtubules "HPA038748: AB_2676188, HPA038752: , HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (5.28e-2)" "unprognostic (3.88e-2)" "unprognostic (7.92e-3)" "unprognostic (7.13e-2)" "unprognostic (2.46e-1)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (2.02e-2)" "unprognostic (7.69e-4)" "unprognostic (7.23e-3)" "unprognostic (5.20e-2)" "unprognostic (5.15e-4)" "unprognostic (2.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-1)" "unprognostic (2.52e-2)" 31.3 10.3 18.1 26.1 16.8 44.2 26.1 11.0 31.9 21.4 40.8 19.6 9.1 29.4 22.4 24.2 22.5 19.9 9.3 23.5 12.1 13.9 21.2 22.1 22.2 21.2 17.3 45.2 26.9 18.4 3.9 15.7 14.4 19.3 20.1 26.1 16.3 14.7 13.6 51.8 11.3 27.5 10.4 31.9 11.4 23.6 25.1 16.3 16.5 12.2 18.6 16.6 15.7 20.7 80.9 12.9 30.7 21.1 64.1 90.4 14.4 26.5 25.4 16.9 20.2 11.5 21.3 16.0 6.6 32.0 25.1 23.7 20.0 26.4 29.4 29.4 21.3 36.5 47.1 2.3 22.8 30.9 14.9 83.2 23.9 55.7 58.5 97.3 29.2 11.5 13.9 50.8 43.8 44.2 7.8 20.8 13.1 14.8 31.4 11.7 25.4 39.8 17.9 34.0 0.4 0.5 54.4 28.6 15.6 30.2 36.7 26.7 128.6 23.4 23.2 22.9 50.1 41.7 16.2 35.5 39.1 27.0 31.1 11.9 16.2 15.2 2.0 8.3 1.0 11.8 1.5 1.3 4.5 11.3 2.0 1.8 34.9 2.4 15.6 17.7 1.8 1.7 18.1 16.8 11.0 31.9 23.5 12.1 21.2 17.3 14.4 10.4 25.1 20.7 2.9 89.8 83.7 95.0 34.8 2.2 47.3 0.6 10.8 2.0 16.9 9.3 20.2 11.5 15.2 12.9 4.2 1.3 28.1 10.7 0.0 37.4 47.3 11.4 8.5 3.7 3.6 15.5 3.7 16.2 14.0 31.8 6.1 20.0 53.7 21.2 3.3 9.9 13.7 0.0 4.4 7.4 0.0 45.3 3.4 43.8 28.3 49.6 1.8 17.8 61.8 13.3 6.2 28.1 0.7 26.4 174.5 17.0 13.3 22.2 6.9 8.6 9.1 9.8 13.1 14.0 18.1 47.5 13.0 38.2 6.3 1.5 12.4 8.4 21.0 41.3 NCBP3 "C17orf85, ELG, HSA277841" ENSG00000074356 "Nuclear cap binding subunit 3" Q53F19 17 3802158-3846246 "Predicted intracellular proteins" "Antiviral defense, mRNA capping, mRNA processing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008959, HPA013195" Supported Approved "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA008959: AB_2668184, HPA013195: AB_2668800" "unprognostic (1.39e-1)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (3.49e-3)" "unprognostic (1.97e-2)" "unprognostic (5.47e-2)" "unprognostic (2.53e-1)" "unprognostic (2.06e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.23e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.90e-4)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-1)" "unprognostic (5.68e-2)" "unprognostic (5.36e-2)" 9.4 8.2 8.1 7.9 10.2 17.1 8.8 8.8 9.6 11.3 7.7 10.0 8.4 8.3 3.5 9.6 10.7 4.9 9.4 8.5 9.2 8.5 6.9 8.1 6.5 8.7 9.7 10.8 12.0 5.8 6.8 7.1 9.7 8.5 5.8 10.4 9.4 4.3 8.8 11.8 10.3 5.8 8.6 10.8 9.4 16.8 9.1 13.9 8.4 3.3 5.4 9.5 9.4 15.2 12.4 15.8 14.3 10.6 7.3 5.3 7.0 8.3 5.6 11.4 7.2 6.3 4.7 10.9 7.3 8.8 5.4 22.2 10.8 10.9 14.5 13.6 14.9 8.9 7.7 7.0 6.1 5.4 12.6 8.2 4.6 10.9 11.5 9.1 9.6 16.0 11.2 11.1 8.5 4.1 19.7 9.6 13.1 5.6 5.9 33.8 11.3 7.1 5.9 6.3 5.2 11.2 17.4 5.9 11.9 11.6 9.1 11.2 9.8 6.5 8.9 10.3 18.2 5.9 6.0 9.3 8.3 9.6 10.3 0.9 2.0 2.6 2.2 1.3 1.9 1.7 1.8 3.0 1.3 1.1 3.0 2.5 2.8 1.4 0.8 2.1 3.2 1.2 8.1 10.2 8.8 9.6 8.5 9.2 8.7 9.7 9.7 8.6 9.1 15.2 45.1 51.3 41.2 0.0 31.2 0.0 26.8 0.0 26.2 44.8 32.2 27.3 0.0 22.8 24.1 25.8 35.5 93.6 59.5 13.1 13.7 24.8 13.5 49.8 63.2 27.8 10.9 21.7 0.0 23.5 21.0 31.1 29.6 48.2 24.0 56.7 29.6 21.5 23.3 33.7 0.0 16.6 0.0 29.9 0.0 17.0 24.8 28.3 0.0 0.0 36.7 20.9 46.4 0.0 0.0 26.8 16.9 18.8 37.7 28.6 20.3 18.2 35.0 45.4 32.9 42.4 27.8 48.0 50.6 30.9 0.0 99.3 34.3 34.1 19.4 28.4 NDEL1 "MITAP1, NDE1L1, NDE2, NUDEL" ENSG00000166579 "NudE neurodevelopment protein 1 like 1" Q9GZM8 17 8413131-8490411 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 134.5;Suprabasal keratinocytes: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017916 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "HPA017916: AB_1854337" "unprognostic (6.34e-2)" "unprognostic (4.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-3)" "unprognostic (6.98e-3)" "unprognostic (1.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.77e-3)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (4.66e-2)" "unprognostic (5.89e-2)" "unprognostic (6.73e-3)" "unprognostic (8.82e-2)" "unprognostic (1.01e-1)" "unprognostic (7.63e-3)" 42.8 60.3 18.2 37.0 23.1 109.8 33.2 19.4 26.2 36.6 17.6 30.9 18.4 29.2 20.3 54.7 32.1 40.7 30.0 23.8 20.9 19.8 43.9 44.4 23.2 18.0 19.2 46.6 27.8 18.0 35.0 39.9 20.9 25.5 23.1 25.3 32.5 22.3 43.6 91.3 24.8 26.7 15.3 29.0 25.8 26.4 20.6 24.4 23.2 31.1 26.8 37.8 39.8 23.5 41.9 36.6 34.2 29.4 50.9 61.9 28.1 87.2 72.6 61.4 64.0 32.0 22.2 24.0 28.9 97.1 34.8 47.7 30.9 34.6 62.9 40.1 50.1 48.0 59.8 38.7 54.5 18.4 98.4 41.2 66.7 52.8 60.0 44.7 49.8 37.0 29.0 27.6 54.1 17.9 27.2 15.7 14.9 26.2 20.4 28.2 26.9 19.8 27.7 23.6 16.2 17.8 52.9 25.4 29.4 36.0 17.3 12.6 65.6 48.7 18.4 45.4 48.4 19.3 42.5 19.3 61.0 27.4 50.3 85.5 28.3 98.2 35.1 27.6 37.0 25.5 31.3 34.8 23.9 26.1 30.4 27.9 175.0 32.8 24.7 20.6 36.5 36.3 18.2 23.1 19.4 26.2 23.8 20.9 18.0 19.2 20.9 15.3 20.6 23.5 48.4 12.8 20.9 12.1 33.8 79.0 55.3 18.3 27.3 13.9 24.1 20.4 17.5 12.8 18.1 12.9 20.9 18.9 39.7 36.8 9.8 13.6 86.8 34.8 21.5 26.4 4.2 37.5 27.0 12.2 37.1 26.4 47.9 63.5 80.5 13.3 18.5 12.8 14.1 8.4 22.0 37.1 20.3 13.2 74.0 134.5 12.8 40.8 32.0 18.7 13.2 8.8 19.6 14.6 19.6 24.0 42.6 14.7 38.2 36.0 21.8 5.8 11.3 14.1 6.6 24.7 40.1 8.3 10.0 25.0 136.7 57.3 40.1 11.8 17.6 73.4 NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.7;granulocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 110.2" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA051515: AB_2681517" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" 14.9 16.7 11.6 19.6 11.6 53.6 13.3 15.7 14.2 15.7 10.6 13.6 10.7 15.7 11.6 16.8 15.0 15.1 11.4 11.6 11.7 14.4 10.9 17.0 24.6 12.6 11.4 15.8 14.1 18.4 15.8 12.5 11.2 15.6 12.1 14.9 17.7 14.2 8.9 18.8 17.4 15.8 10.4 35.3 13.6 13.6 12.5 31.9 13.3 8.5 23.9 15.3 15.4 11.5 10.0 7.9 16.7 26.2 20.9 23.0 9.1 12.3 24.5 13.4 13.3 4.6 12.4 9.5 7.1 21.8 13.6 11.6 8.1 11.8 9.6 23.4 8.5 9.3 7.0 7.3 36.7 11.8 110.2 22.9 14.5 21.4 22.4 41.1 17.5 17.9 9.2 33.8 16.6 8.1 12.7 13.4 4.5 6.4 36.4 8.5 8.2 5.9 11.5 7.2 5.5 9.0 9.9 23.5 7.5 11.3 18.6 18.6 29.5 6.3 7.8 9.1 8.4 17.4 8.0 11.8 7.2 17.0 5.5 0.7 2.7 1.1 2.7 1.9 3.1 1.2 2.3 2.3 2.0 1.3 2.6 3.4 2.8 1.1 1.7 3.4 1.6 1.8 11.6 11.6 15.7 14.2 11.6 11.7 12.6 11.4 11.2 10.4 12.5 11.5 1.5 0.0 3.0 13.7 5.4 1.3 0.8 0.6 1.2 0.7 4.1 2.3 1.8 0.0 1.8 0.0 0.0 1.4 3.6 4.7 0.0 5.4 7.5 0.8 1.2 1.1 2.4 7.8 7.5 9.6 1.5 1.9 4.6 0.7 14.5 0.3 1.4 4.2 5.2 1.7 7.6 2.6 2.0 8.5 3.1 10.4 0.0 10.8 1.8 2.8 5.4 0.8 0.0 5.0 5.0 7.0 3.2 0.0 10.6 1.3 2.4 7.4 2.7 0.8 0.0 1.4 1.5 2.3 1.7 4.7 1.6 6.2 5.3 0.3 2.2 1.9 NEMF "FLJ10051, NY-CO-1, SDCCAG1" ENSG00000165525 "Nuclear export mediator factor" O60524 14 49782083-49852821 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004160 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 830000 "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA004160: AB_1079884" "unprognostic (9.92e-2)" "unprognostic (6.03e-2)" "unprognostic (4.44e-2)" "unprognostic (3.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.65e-1)" "unprognostic (9.15e-3)" "unprognostic (7.62e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.50e-1)" "unprognostic (1.12e-1)" "prognostic favorable (2.85e-4)" "unprognostic (3.61e-1)" "unprognostic (2.36e-1)" "unprognostic (8.98e-2)" "unprognostic (1.81e-2)" 16.5 13.8 9.5 18.0 13.0 42.1 14.7 18.1 14.7 16.2 5.9 13.6 10.0 16.2 13.5 22.5 12.2 13.2 17.7 7.9 10.6 14.9 11.9 13.8 17.9 11.8 11.6 15.2 15.2 24.8 10.3 18.2 11.9 16.0 14.5 14.7 14.6 15.8 23.0 14.3 13.6 15.7 10.9 15.5 14.1 10.7 10.7 16.3 18.5 21.5 17.9 18.0 11.6 18.4 34.3 39.2 35.9 24.1 37.3 31.0 32.1 42.0 28.3 27.6 27.3 23.2 35.3 13.3 32.0 35.7 21.2 47.5 34.1 26.7 42.2 38.9 22.7 38.7 40.3 29.1 23.8 50.7 33.4 26.8 19.6 29.9 27.2 36.3 39.8 23.8 47.3 36.2 37.7 30.6 31.2 17.9 21.9 28.6 36.8 32.6 35.5 20.8 33.7 44.8 23.6 22.2 41.6 40.4 39.2 37.2 37.6 31.1 47.2 39.2 34.4 26.6 28.9 24.5 47.6 40.9 14.7 23.9 35.5 76.4 38.9 45.8 45.7 36.9 44.8 83.7 47.1 44.4 33.9 86.7 55.6 59.1 61.3 47.8 54.4 79.7 46.1 20.3 9.5 13.0 18.1 14.7 7.9 10.6 11.8 11.6 11.9 10.9 10.7 18.4 66.2 41.7 76.7 65.3 81.1 34.4 67.4 81.6 29.6 92.1 31.7 43.1 97.2 34.3 74.4 44.1 100.1 85.8 78.4 51.8 37.2 57.0 13.9 52.2 60.1 65.2 54.0 57.0 75.7 39.1 58.1 53.0 41.8 60.7 89.3 68.0 49.6 28.1 58.9 131.2 80.7 48.9 71.2 48.7 57.0 13.1 65.9 57.9 24.9 62.8 79.4 54.8 82.4 56.8 99.5 46.4 68.5 67.4 50.0 66.1 59.4 29.9 82.4 90.0 72.3 65.7 70.7 83.0 58.3 32.5 34.1 108.4 66.9 64.1 54.6 88.6 NFKBIA "IkappaBalpha, IKBA, MAD-3, NFKBI" ENSG00000100906 "NFKB inhibitor alpha" P25963 14 35401513-35404749 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1114.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 4056.6;Langerhans cells: 4828.7;Suprabasal keratinocytes: 3420.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 391.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003815, HPA029207" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB003815: AB_344886, HPA029207: AB_10603122" "prognostic favorable (1.33e-5)" "unprognostic (3.39e-1)" "unprognostic (7.29e-2)" "unprognostic (7.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (2.46e-1)" "unprognostic (2.46e-1)" "unprognostic (7.19e-2)" "unprognostic (2.32e-2)" "unprognostic (3.69e-1)" "unprognostic (4.44e-2)" "unprognostic (9.74e-2)" "unprognostic (3.80e-2)" 281.0 171.3 75.6 150.7 78.0 1114.7 171.4 75.4 92.5 123.8 78.3 121.0 61.2 95.5 29.6 151.8 141.2 130.4 145.5 71.4 75.9 104.5 208.1 366.0 122.6 90.1 76.2 255.7 101.9 68.8 92.4 92.7 81.6 112.6 80.9 18.7 118.3 110.0 139.7 260.5 148.5 92.7 77.0 226.2 130.7 31.7 84.9 123.2 111.9 138.3 181.4 366.2 166.8 79.8 62.5 54.1 20.1 18.2 114.7 75.9 71.1 25.2 240.7 53.3 47.3 16.9 36.5 37.5 66.1 40.2 125.2 79.5 38.3 104.9 76.1 229.2 14.9 18.6 39.9 101.4 68.6 29.9 15.0 83.1 103.5 36.4 92.2 35.5 48.6 18.4 15.9 58.4 38.6 73.0 39.2 71.0 18.6 60.0 33.1 87.8 23.1 31.6 92.8 391.7 17.9 31.2 67.2 115.9 29.7 41.0 66.1 62.2 91.7 72.8 26.5 21.3 41.0 70.9 77.7 64.5 60.8 22.0 15.3 322.0 444.9 301.4 175.3 267.2 264.0 258.4 207.1 182.5 428.9 329.7 178.1 153.0 942.9 285.9 183.7 233.0 154.9 506.4 75.6 78.0 75.4 92.5 71.4 75.9 90.1 76.2 81.6 77.0 84.9 79.8 802.9 535.2 914.0 14.4 505.6 4056.6 1862.8 2061.4 1729.6 27.0 430.7 414.0 188.6 367.4 719.2 62.5 12.5 196.4 762.2 447.8 195.6 875.0 4.3 703.8 935.6 1079.8 203.5 87.8 7.1 394.8 174.9 1145.1 333.8 1440.1 906.1 68.2 313.4 147.2 791.2 48.8 5.1 453.0 634.7 491.4 4828.7 14.7 153.1 1609.0 1085.1 39.4 428.1 95.2 97.9 6.6 8.6 383.5 511.5 116.2 1039.4 1412.0 1051.6 115.9 298.2 37.4 203.8 956.9 847.2 3.3 26.4 1544.6 3420.6 660.0 838.4 91.8 346.0 1004.6 NFKBID "IkappaBNS, IkBNS, TA-NFKBH" ENSG00000167604 "NFKB inhibitor delta" Q8NI38 19 35887653-35902303 "Predicted intracellular proteins, Transcription factors" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.9" "Cell type enhanced" "Detected in many" "B-cells: 152.7;granulocytes: 90.3;Langerhans cells: 418.5;Macrophages: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054778 Uncertain "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Cytosol "Nuclear bodies, Plasma membrane" "HPA054778: " "prognostic favorable (6.01e-4)" "unprognostic (9.60e-2)" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-2)" "prognostic favorable (5.43e-4)" "unprognostic (4.21e-2)" "unprognostic (7.68e-2)" "unprognostic (3.83e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (5.64e-2)" "unprognostic (6.83e-2)" "unprognostic (1.04e-1)" "unprognostic (5.21e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.34e-6)" 4.0 1.8 0.7 4.4 0.6 15.9 2.5 2.7 1.6 1.9 2.1 2.3 1.1 1.8 0.0 2.1 3.0 2.4 1.5 0.8 1.4 2.5 1.5 5.6 4.8 1.4 0.9 3.3 2.1 0.9 4.2 0.8 1.2 2.2 0.8 0.7 1.6 0.5 0.4 2.2 4.0 0.5 1.0 5.4 2.0 0.4 1.3 5.2 3.9 0.2 3.1 2.2 2.0 1.7 3.3 3.0 0.6 2.0 0.3 0.5 1.4 2.0 2.4 2.1 1.5 0.7 2.6 4.0 1.5 2.1 1.9 1.7 2.1 1.6 0.9 2.3 0.4 2.4 4.9 0.7 0.5 2.1 7.0 0.7 1.0 3.9 0.9 0.5 0.8 1.8 0.5 2.4 0.4 2.6 1.7 2.5 0.8 0.6 0.6 0.9 0.4 0.8 1.8 1.4 1.0 0.8 2.7 2.1 0.2 0.5 0.9 2.1 0.8 3.3 3.0 1.5 1.4 1.7 0.6 4.6 1.8 4.9 0.5 0.0 0.9 1.7 1.4 0.6 1.1 3.3 0.6 1.1 0.9 5.5 1.0 0.6 3.2 1.5 1.1 1.2 1.5 0.5 0.7 0.6 2.7 1.6 0.8 1.4 1.4 0.9 1.2 1.0 1.3 1.7 11.7 0.0 11.3 2.9 152.7 29.7 14.3 12.9 34.7 8.0 10.9 7.5 1.1 5.7 5.6 1.8 20.9 1.3 58.9 5.7 0.0 2.5 0.1 27.8 6.8 21.5 3.0 1.7 4.9 1.0 2.8 11.3 2.0 80.8 90.3 3.8 9.3 0.3 39.2 0.0 3.4 5.7 2.0 31.0 418.5 0.4 1.2 89.4 19.6 2.8 40.0 1.0 13.4 1.5 0.5 2.8 2.1 1.9 38.1 13.8 9.2 1.7 3.9 9.2 0.0 3.3 6.7 0.4 1.0 20.7 33.4 1.0 45.3 2.4 6.2 10.0 NFRKB "DKFZp547B2013, INO80G" ENSG00000170322 "Nuclear factor related to kappaB binding protein" Q6P4R8 11 129863636-129895590 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007082, HPA007128" Approved Enhanced Nucleoplasm Yes No "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA007082: AB_1079481, HPA007128: AB_1079482" "unprognostic (1.22e-1)" "unprognostic (3.42e-2)" "unprognostic (2.12e-1)" "unprognostic (9.41e-2)" "unprognostic (6.56e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (6.36e-3)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "unprognostic (5.31e-2)" "unprognostic (9.22e-2)" "unprognostic (4.15e-2)" "unprognostic (6.57e-2)" "unprognostic (7.14e-2)" "unprognostic (3.93e-2)" 9.8 9.0 7.2 10.8 9.9 22.7 11.0 9.7 7.3 15.0 9.1 11.8 13.1 15.6 17.5 13.2 17.9 9.9 7.5 8.3 6.5 10.6 11.8 10.8 14.5 4.9 5.5 20.6 13.9 10.5 11.7 13.1 5.5 12.4 10.1 9.8 14.3 13.3 15.4 21.9 12.4 13.5 4.5 11.2 11.2 20.3 7.2 15.0 20.0 9.7 13.4 12.6 13.8 6.7 17.9 16.8 37.4 20.3 15.6 15.4 23.5 12.2 11.0 14.2 13.9 52.6 30.1 42.6 32.5 9.4 20.8 44.8 36.5 23.8 13.2 16.9 31.9 84.2 32.8 22.2 11.4 21.7 27.3 9.9 25.9 23.3 24.3 16.3 24.9 28.1 49.9 31.5 14.4 16.2 18.6 37.1 19.1 26.2 39.1 27.2 16.3 19.6 17.7 55.6 19.0 20.0 27.4 26.7 7.3 27.5 62.3 19.9 19.7 21.1 20.6 15.6 15.4 10.0 13.3 39.0 8.8 41.9 18.5 6.6 5.1 6.3 6.0 5.8 6.3 3.3 6.1 5.1 5.1 3.9 5.0 4.2 6.0 2.4 5.2 4.5 4.4 4.5 7.2 9.9 9.7 7.3 8.3 6.5 4.9 5.5 5.5 4.5 7.2 6.7 6.2 9.6 15.0 17.0 10.0 29.3 16.8 17.5 18.8 10.2 12.1 10.0 7.6 20.0 17.0 7.3 10.4 19.2 7.8 9.5 7.9 11.9 14.8 12.9 14.4 9.5 8.5 9.4 13.1 10.0 15.6 9.7 6.1 17.8 10.8 14.1 8.9 10.9 10.4 8.4 10.7 9.7 8.2 7.7 6.2 7.1 14.6 8.4 14.2 9.4 12.4 9.7 12.3 12.1 7.7 10.9 8.0 10.5 10.5 15.4 15.6 8.1 12.9 11.1 32.9 10.8 14.2 43.0 49.0 10.7 35.2 23.3 13.1 9.4 12.2 17.9 NFYA "CBF-B, HAP2, NF-YA" ENSG00000001167 "Nuclear transcription factor Y subunit alpha" P23511 6 41072945-41099976 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009250, HPA050779" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB009250: AB_2152107, HPA050779: AB_2681234" "unprognostic (2.56e-1)" "unprognostic (4.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.95e-2)" "unprognostic (4.57e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.23e-3)" "unprognostic (5.62e-3)" "unprognostic (1.03e-1)" "unprognostic (1.92e-3)" "unprognostic (3.11e-1)" "unprognostic (5.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.92e-3)" 10.8 8.9 13.3 14.0 18.1 40.7 15.6 14.3 13.2 11.3 9.6 11.9 9.9 14.9 14.7 10.8 11.6 12.5 8.8 12.5 13.4 10.1 14.3 11.8 19.5 15.8 16.6 18.7 11.5 15.3 9.0 13.8 15.5 13.6 14.6 21.5 9.4 8.0 9.3 10.6 11.2 10.8 13.6 14.5 12.6 38.5 14.8 41.5 18.4 12.4 20.5 14.6 9.4 24.3 32.8 26.3 49.2 82.7 19.9 19.3 20.9 24.2 22.4 37.2 31.4 34.6 23.3 39.4 19.7 16.0 19.6 21.0 30.1 29.1 40.9 28.4 38.0 51.7 23.2 49.4 14.1 55.0 43.3 12.3 24.4 29.8 40.0 18.1 32.6 64.5 51.4 46.4 36.9 32.4 62.5 22.1 22.1 95.8 25.9 50.3 27.1 29.6 27.2 43.8 49.8 34.3 21.1 18.9 37.5 31.2 17.7 55.1 32.2 65.7 35.6 13.2 46.9 18.2 19.8 64.2 13.0 46.2 26.5 2.7 2.9 4.8 5.8 3.9 7.6 3.7 5.4 6.4 3.3 4.1 5.7 6.3 8.0 6.5 3.5 4.3 6.7 3.2 13.3 18.1 14.3 13.2 12.5 13.4 15.8 16.6 15.5 13.6 14.8 24.3 7.6 9.6 3.9 6.2 11.1 14.5 9.9 4.2 2.8 4.1 13.2 7.1 4.7 11.5 5.3 11.0 4.2 7.7 11.7 9.3 1.9 11.3 41.4 7.4 7.7 7.5 4.8 12.2 4.4 7.4 12.5 6.8 5.1 8.1 2.5 11.9 7.5 7.0 10.0 0.0 5.1 4.2 4.1 9.3 14.0 44.4 3.7 6.4 7.2 10.3 7.2 3.3 7.2 5.0 13.8 9.6 9.6 3.0 5.6 12.8 5.1 2.6 6.9 5.0 0.0 4.3 8.3 20.0 8.2 6.3 15.9 10.8 10.1 5.6 7.6 18.7 NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469689-23509862 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: AB_1079483" "unprognostic (2.63e-3)" "unprognostic (7.65e-2)" "unprognostic (2.84e-1)" "unprognostic (4.16e-3)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (8.87e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (3.87e-3)" "unprognostic (7.10e-2)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (9.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-1)" 32.2 26.4 25.6 23.3 28.4 64.4 40.3 30.5 37.7 30.5 25.0 30.1 23.4 34.7 32.5 26.2 32.0 17.6 23.7 25.9 26.6 31.3 32.9 24.2 35.3 27.1 27.0 39.6 25.7 33.3 20.8 29.2 27.7 24.8 29.0 25.2 24.6 26.6 53.4 35.2 26.8 31.4 27.7 28.6 27.0 28.6 26.9 37.5 28.4 39.2 36.8 32.3 27.7 31.7 37.6 73.1 54.5 51.5 52.0 37.3 72.1 48.6 50.7 101.3 81.4 72.1 66.8 92.6 35.0 44.7 71.1 63.7 109.0 60.1 118.7 61.8 57.3 83.2 44.1 229.3 70.5 110.4 56.9 46.5 75.0 79.9 94.4 39.6 52.2 69.5 93.6 64.1 50.4 88.8 82.3 86.0 69.5 84.8 97.1 67.1 65.6 47.9 65.7 70.4 55.6 62.8 57.6 68.3 83.8 55.0 42.2 70.4 39.8 47.8 57.3 45.1 71.3 79.4 148.7 133.3 20.6 56.1 52.2 67.0 62.3 58.5 88.0 71.8 93.5 129.0 94.6 89.9 74.8 107.7 121.3 95.5 19.1 109.5 71.7 79.1 116.1 93.3 25.6 28.4 30.5 37.7 25.9 26.6 27.1 27.0 27.7 27.7 26.9 31.7 33.8 35.3 29.2 2.9 52.1 70.6 63.8 78.2 72.8 23.2 25.5 31.2 20.2 21.5 46.8 27.6 16.7 59.3 45.3 19.9 33.2 38.6 7.2 24.3 25.9 36.5 24.6 35.1 7.5 36.0 43.3 34.4 16.3 27.5 45.0 23.2 25.4 21.4 29.8 25.2 6.8 22.7 28.5 19.2 39.0 6.9 35.1 21.1 32.0 9.4 34.3 26.8 46.4 4.0 11.0 31.1 22.8 28.2 30.4 42.9 25.8 35.5 36.6 28.6 19.7 51.5 36.0 68.7 64.2 39.6 67.6 57.2 47.6 20.5 27.2 49.5 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NPM3 ENSG00000107833 "Nucleophosmin/nucleoplasmin 3" O75607 10 101781325-101783413 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036295, HPA036296" Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoli, Actin filaments, Cytosol" "HPA036295: AB_10671244, HPA036296: AB_10672083" "unprognostic (3.41e-2)" "unprognostic (3.70e-2)" "unprognostic (4.33e-2)" "unprognostic (1.75e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.00e-2)" "unprognostic (1.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.45e-2)" "unprognostic (1.35e-2)" "unprognostic (2.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (5.69e-2)" "unprognostic (9.58e-2)" 12.7 19.5 9.9 18.5 10.2 27.2 19.0 7.8 10.4 19.6 9.6 15.5 8.3 17.2 10.1 26.6 15.3 9.8 8.4 9.6 11.6 16.4 12.3 10.2 23.3 8.4 8.5 20.6 30.3 16.4 12.4 16.3 8.6 13.4 19.3 1.1 15.1 8.2 13.3 16.7 10.7 19.9 8.5 14.8 13.1 17.1 11.6 20.3 11.1 10.1 25.9 20.9 16.7 9.3 94.8 117.2 34.2 226.2 76.5 80.0 36.1 50.0 75.7 75.8 64.4 126.5 117.1 154.8 91.0 56.0 41.6 99.2 192.6 211.8 59.3 66.1 199.8 124.5 50.5 206.0 86.1 286.6 87.4 69.6 100.8 105.2 417.0 39.0 100.6 187.1 156.9 83.7 63.3 173.8 121.0 371.8 60.7 131.1 89.1 93.3 179.2 158.0 75.0 45.8 70.0 45.1 31.2 72.5 144.7 41.8 94.4 59.0 40.1 30.0 95.8 44.8 94.1 36.0 39.9 179.7 41.9 263.4 31.8 0.0 2.8 0.0 3.6 4.0 6.5 4.0 5.9 6.9 6.4 4.8 9.5 9.8 0.1 8.1 0.8 8.3 2.6 5.1 9.9 10.2 7.8 10.4 9.6 11.6 8.4 8.5 8.6 8.5 11.6 9.3 5.1 3.2 5.0 1.0 15.3 62.7 79.6 121.4 28.5 1.4 55.5 54.4 2.9 28.6 32.0 36.8 0.0 91.4 15.6 16.3 78.2 54.0 8.9 7.3 22.1 21.6 24.2 17.9 2.7 41.2 90.6 29.7 13.7 10.5 16.5 19.6 15.0 19.0 68.6 0.0 2.0 33.1 46.8 21.1 69.9 10.9 28.0 18.0 30.2 1.9 14.7 2.5 18.6 1.5 1.0 34.2 12.7 23.7 19.1 118.5 3.1 61.6 16.4 2.0 6.6 47.9 21.6 46.5 91.3 21.3 49.9 60.7 18.5 29.0 46.9 62.8 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 129.3;bone marrow: 130.8;ovary: 129.2" "Cell type enhanced" "Detected in many" "B-cells: 511.7;dendritic cells: 410.4;Langerhans cells: 782.3;Macrophages: 577.5;T-cells: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0;HMC-1: 10.9;SK-MEL-30: 8.1;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 40.0 129.3 4.3 24.5 44.1 130.8 15.6 36.2 8.8 18.3 5.9 9.5 2.9 15.0 1.7 11.4 28.2 32.7 36.6 15.1 3.6 19.2 20.2 18.8 6.3 3.2 9.2 129.2 9.2 8.8 54.0 5.2 2.8 25.6 18.7 5.3 19.2 15.5 11.6 12.8 7.8 14.5 0.9 4.6 19.9 5.6 2.5 9.7 15.2 7.8 1.4 50.9 14.0 6.4 0.9 1.3 0.5 1.8 3.2 0.7 0.9 1.1 5.5 0.4 1.3 0.0 3.3 0.0 1.2 0.4 0.4 1.6 2.6 0.7 0.4 1.3 1.4 1.0 16.0 0.0 0.6 0.7 10.9 0.6 1.2 0.4 0.4 2.1 0.3 0.0 1.6 1.0 1.1 1.9 0.0 0.8 2.1 1.5 0.8 0.2 0.7 3.3 0.6 0.8 2.7 0.1 2.6 4.1 8.1 0.3 0.2 1.0 0.7 2.9 0.8 0.7 0.4 14.2 1.8 0.0 5.3 1.0 7.0 1.9 1.7 2.4 1.0 0.3 0.5 0.4 0.3 0.5 1.9 0.3 0.5 0.2 6.5 0.0 0.7 0.0 0.4 0.5 4.3 44.1 36.2 8.8 15.1 3.6 3.2 9.2 2.8 0.9 2.5 6.4 70.7 25.6 124.7 7.8 511.7 218.6 25.8 87.5 298.7 11.8 120.8 160.1 11.9 17.2 58.3 71.7 50.1 4.7 410.4 35.0 0.0 13.1 36.7 209.6 33.9 111.9 206.4 12.0 5.8 9.1 6.5 164.9 103.9 349.7 349.3 4.3 45.0 6.8 125.1 0.0 0.8 95.4 42.7 161.1 782.3 37.2 4.1 577.5 241.9 5.6 7.9 1.6 3.1 4.0 2.3 11.7 41.9 0.7 203.5 49.1 25.9 0.4 54.6 33.4 13.1 63.0 169.8 1.8 3.3 230.2 213.7 9.9 465.1 34.4 57.5 29.5 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 20.3;Granulosa cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm No No "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "CAB068246: AB_2665690, CAB068247: AB_2665689, HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavorable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 10.1 8.4 12.7 16.5 13.0 54.9 9.9 23.6 15.2 9.4 0.8 19.6 18.6 10.7 7.3 13.6 8.4 8.3 15.8 11.8 11.5 9.8 8.3 12.6 25.4 9.8 8.6 7.7 13.5 12.0 13.8 12.2 12.0 9.7 22.5 28.5 11.6 8.4 16.7 11.6 18.3 12.4 4.4 14.1 12.5 37.2 12.6 59.8 17.4 13.7 24.3 9.7 9.2 14.9 124.0 58.6 168.3 71.2 17.5 26.5 44.2 98.2 85.4 115.2 128.8 44.6 141.4 117.5 31.4 78.0 158.5 50.2 114.4 74.3 195.0 58.3 47.7 151.3 81.7 25.5 18.6 89.5 74.9 9.9 19.8 101.2 89.9 60.1 92.2 123.4 81.7 132.2 95.8 42.1 243.3 99.7 68.8 60.1 77.1 137.8 106.7 42.9 45.4 57.4 115.6 82.7 78.4 29.2 31.7 71.4 68.9 52.2 64.9 109.0 87.4 72.8 188.1 54.1 72.9 113.7 66.0 81.9 108.0 4.0 1.1 1.3 1.0 0.8 1.1 0.9 1.5 1.2 1.2 1.7 1.1 0.8 3.4 1.2 0.5 2.1 2.9 0.7 12.7 13.0 23.6 15.2 11.8 11.5 9.8 8.6 12.0 4.4 12.6 14.9 12.6 12.8 18.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 15.3 9.1 0.0 0.0 8.1 12.9 0.0 15.7 7.2 0.0 3.9 10.4 0.0 13.0 11.7 6.3 0.0 0.0 0.0 7.1 10.0 6.0 0.0 20.3 2.5 69.3 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 5.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 4.9 0.0 0.0 4.0 7.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 3.4 5.2 3.7 0.0 0.0 NUDT4B NUDT4P1 ENSG00000177144 "Nudix hydrolase 4B" A0A024RBG1 1 148748894-148750099 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.8" "Cell line enhanced" "Detected in all" "CACO-2: 42.1;RT4: 34.5" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017593: AB_1854703, HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (1.24e-1)" "unprognostic (4.01e-2)" 4.9 6.8 0.2 3.6 0.4 23.6 1.8 0.0 0.9 4.4 0.3 5.7 5.3 3.7 2.6 8.1 7.0 17.7 20.8 0.5 0.6 9.8 3.9 2.6 6.8 1.3 0.5 16.1 11.9 4.6 0.3 7.7 0.4 7.5 6.1 0.6 23.6 3.1 5.3 1.3 5.2 3.6 0.3 3.0 4.1 7.7 0.3 3.2 7.9 8.1 3.7 11.1 0.6 0.6 3.5 3.8 1.5 4.7 6.3 5.1 9.3 4.1 6.2 4.4 4.2 42.1 14.8 3.5 1.7 3.7 4.2 5.7 6.8 3.0 2.2 11.0 3.3 8.5 2.3 5.4 8.4 5.8 2.6 10.6 9.7 5.5 5.1 5.3 16.5 4.3 17.6 13.8 4.2 3.0 7.9 1.1 8.3 3.4 6.2 9.7 2.2 10.0 3.2 34.5 3.0 4.4 3.5 8.6 23.7 1.0 11.7 11.0 9.1 5.8 4.5 9.6 6.3 3.2 5.2 4.5 2.7 8.7 17.4 0.0 0.1 2.8 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.2 0.4 0.0 0.9 0.5 0.6 1.3 0.5 0.4 0.3 0.3 0.6 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 NUFIP1 "NUFIP, Rsa1" ENSG00000083635 "Nuclear FMR1 interacting protein 1" Q9UHK0 13 44939249-44989471 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029958, HPA029959" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "HPA029958: AB_10598911, HPA029959: AB_10602308" "unprognostic (2.01e-1)" "unprognostic (5.32e-3)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (1.70e-2)" "unprognostic (2.98e-3)" "unprognostic (2.32e-1)" "unprognostic (1.45e-2)" "unprognostic (2.91e-2)" "unprognostic (9.74e-3)" "unprognostic (4.52e-1)" "unprognostic (3.95e-2)" "unprognostic (3.73e-2)" "unprognostic (4.04e-2)" "unprognostic (4.89e-2)" "unprognostic (3.31e-1)" "unprognostic (5.24e-2)" 3.2 3.7 3.2 2.8 3.4 7.9 4.6 2.9 4.6 3.6 2.1 2.6 2.8 4.5 5.5 3.3 3.5 2.4 2.5 3.3 3.0 4.0 4.1 2.3 3.7 2.6 3.2 4.3 3.8 4.0 1.8 3.0 2.9 3.4 3.0 2.6 3.3 3.2 4.8 3.4 2.4 4.0 2.9 3.0 2.8 5.5 3.1 3.6 3.9 3.9 3.8 4.2 2.6 3.9 7.4 5.7 9.5 7.9 6.4 6.6 11.3 8.6 7.4 15.6 9.9 15.6 11.5 21.5 7.0 8.0 9.4 11.3 17.9 12.2 20.2 6.6 14.0 16.4 3.7 14.0 10.5 21.3 6.4 6.9 11.0 10.5 15.8 6.0 7.9 10.9 13.3 3.5 11.1 8.5 17.8 13.4 22.5 19.5 9.3 17.3 9.0 13.1 9.5 6.3 5.2 11.5 7.3 9.9 9.6 8.9 7.5 11.8 6.0 7.9 6.8 10.3 11.9 4.8 7.9 26.7 8.9 14.8 11.4 0.0 2.6 0.8 2.5 2.6 4.7 4.0 2.9 2.8 3.4 4.1 4.5 3.4 0.2 5.9 1.8 4.5 1.7 1.8 3.2 3.4 2.9 4.6 3.3 3.0 2.6 3.2 2.9 2.9 3.1 3.9 11.3 6.4 12.2 6.2 10.5 15.4 11.8 16.7 23.9 7.8 9.8 16.3 4.5 4.3 15.4 5.5 12.5 15.7 11.7 4.2 17.6 14.0 37.2 14.0 21.7 10.9 5.4 14.5 19.2 16.7 15.9 11.9 7.7 18.6 17.7 14.1 7.1 9.7 10.8 8.4 16.9 5.3 12.2 3.4 5.5 63.2 10.8 7.9 8.8 7.5 6.9 9.7 7.2 16.6 14.4 10.8 1.6 11.3 5.0 8.6 3.2 14.8 6.6 6.8 6.6 20.3 15.6 27.1 31.6 14.3 16.6 8.8 9.9 15.7 8.4 7.1 NUP153 HNUP153 ENSG00000124789 "Nucleoporin 153" P49790 6 17615035-17706925 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport, Viral penetration into host nucleus, Virus entry into host cell" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027896, HPA027897, HPA027898, HPA027899" Supported Enhanced "Nuclear membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" "HPA027896: AB_10611243, HPA027897: AB_10601108, HPA027898: AB_10601682, HPA027899: " "unprognostic (2.49e-1)" "unprognostic (5.37e-1)" "unprognostic (3.17e-2)" "unprognostic (6.20e-3)" "unprognostic (3.36e-1)" "unprognostic (7.64e-3)" "unprognostic (2.53e-2)" "unprognostic (6.49e-2)" "unprognostic (1.95e-2)" "unprognostic (7.16e-3)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (3.66e-1)" "unprognostic (5.40e-2)" "unprognostic (8.69e-2)" 16.5 10.3 5.4 18.2 6.1 45.6 16.7 12.5 7.4 15.2 10.1 12.8 10.1 17.0 11.6 16.2 15.0 14.9 11.2 6.2 6.3 13.1 23.4 13.9 23.9 6.1 7.1 18.6 13.2 17.9 9.2 18.9 6.4 12.0 13.1 15.7 12.0 13.1 25.1 15.9 12.8 14.4 6.3 17.8 11.6 26.7 6.8 25.2 13.8 19.5 27.6 18.7 14.5 9.7 55.6 27.2 57.7 50.8 24.9 29.3 57.8 42.3 39.3 61.8 65.7 45.5 24.9 104.3 69.7 37.7 51.9 39.4 68.1 41.0 99.0 56.2 52.7 55.6 29.4 47.0 18.6 81.0 50.2 31.0 32.5 64.9 46.5 23.6 37.0 34.5 131.7 32.5 41.9 29.5 60.5 50.1 45.6 20.8 29.5 80.1 74.2 97.9 27.3 53.1 64.6 37.5 36.0 58.3 36.2 90.5 37.8 29.0 34.8 63.2 36.2 30.2 66.7 41.8 63.8 102.8 15.6 36.8 76.1 1.2 1.3 3.2 2.8 1.2 3.7 1.7 3.5 3.4 1.9 2.1 2.1 2.1 3.4 3.0 1.8 1.1 1.7 1.3 5.4 6.1 12.5 7.4 6.2 6.3 6.1 7.1 6.4 6.3 6.8 9.7 28.9 19.2 23.2 39.8 31.4 76.3 37.9 11.1 51.2 14.2 32.5 18.7 14.3 11.5 11.9 16.5 16.7 20.9 24.0 19.4 1.9 8.8 27.3 69.3 56.8 23.3 20.9 44.0 53.0 6.0 21.7 31.8 23.4 91.0 3.8 17.7 13.6 30.7 17.5 16.8 48.8 13.6 12.2 15.6 36.7 19.6 17.4 27.5 21.4 47.8 12.7 7.2 20.6 37.2 50.5 13.4 7.0 14.7 27.9 41.7 10.1 9.8 23.4 12.7 13.1 55.1 26.4 30.4 22.3 51.8 79.3 23.9 35.8 11.7 16.8 35.1 NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 38000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" 17.9 13.9 13.2 21.3 17.4 52.7 15.5 6.8 23.9 15.3 0.2 17.7 9.9 16.9 12.4 22.3 15.3 12.4 14.2 30.6 10.7 12.8 9.3 15.3 27.7 10.7 9.3 14.9 14.2 14.8 10.8 19.1 9.9 17.7 18.1 31.7 12.2 12.7 20.0 21.6 14.5 19.5 8.3 24.2 15.2 39.8 11.4 34.1 34.3 14.2 30.3 17.1 16.1 11.5 71.3 84.5 71.6 81.0 25.9 34.8 81.0 58.7 48.2 156.2 100.1 119.4 66.1 107.7 60.4 54.9 54.2 120.6 143.3 90.1 149.8 34.0 81.3 72.6 64.7 97.3 35.0 96.7 82.8 29.3 35.7 104.2 64.7 31.6 90.8 95.3 87.8 22.3 72.3 52.4 136.2 81.1 92.1 44.2 95.4 163.9 129.4 108.9 53.1 47.8 66.6 44.1 159.1 54.6 47.3 77.4 43.0 57.9 55.3 68.1 74.0 57.8 67.5 35.0 60.7 190.2 47.4 88.5 67.5 19.3 49.9 195.7 38.9 77.2 45.2 45.4 28.3 40.9 60.9 45.4 28.7 41.0 11.8 51.8 77.5 28.7 39.7 47.4 13.2 17.4 6.8 23.9 30.6 10.7 10.7 9.3 9.9 8.3 11.4 11.5 11.3 6.4 12.3 17.6 13.4 12.0 13.6 20.7 6.2 68.6 9.0 7.6 11.8 1.5 20.2 9.2 10.4 21.1 9.4 8.6 11.7 24.6 11.7 10.9 8.8 16.5 4.9 33.2 51.1 25.5 31.7 12.8 13.7 10.6 17.2 22.3 10.8 7.2 26.6 38.7 49.4 11.2 24.4 17.8 23.8 7.7 23.3 17.3 16.0 33.7 30.3 11.7 8.2 18.1 22.1 21.4 7.2 13.5 8.1 16.5 3.6 11.0 13.0 20.8 13.1 11.4 27.9 54.6 62.2 14.3 16.1 10.3 13.5 22.3 15.3 18.0 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NXT1 "MTR2, P15" ENSG00000132661 "Nuclear transport factor 2 like export factor 1" Q9UKK6 20 23350791-23354771 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 235.3;Suprabasal keratinocytes: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 200.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047471 Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Cytosol "HPA047471: AB_2680061" "unprognostic (6.44e-2)" "unprognostic (2.89e-1)" "unprognostic (3.07e-2)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (2.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.89e-2)" "unprognostic (1.17e-1)" "unprognostic (6.89e-2)" "unprognostic (5.54e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.15e-7)" "unprognostic (2.07e-1)" "unprognostic (1.98e-1)" "unprognostic (9.11e-3)" "unprognostic (9.31e-2)" 26.4 14.2 10.4 12.4 10.4 46.8 20.6 11.0 11.7 18.7 11.0 16.0 6.9 17.8 16.7 19.6 22.8 10.1 15.7 9.9 11.0 19.8 13.7 18.9 13.7 11.1 11.1 23.9 12.5 9.6 17.9 13.0 11.3 14.9 10.1 9.4 12.8 11.6 11.6 22.7 13.8 14.9 11.2 17.6 15.2 17.6 11.2 18.3 14.4 9.5 18.3 21.5 16.9 11.1 46.3 50.6 29.9 31.4 20.7 20.0 27.9 27.7 31.0 44.3 44.5 33.7 44.2 55.0 40.3 27.7 73.0 52.8 35.6 72.6 43.3 26.5 33.2 40.5 10.4 60.4 30.9 43.6 29.5 17.9 47.6 42.8 60.4 17.5 35.7 39.5 54.7 52.6 34.7 60.1 90.7 76.4 25.2 82.3 110.9 61.9 48.4 64.7 27.0 38.5 48.4 28.4 25.4 66.7 53.3 18.2 37.5 50.1 22.7 44.6 36.9 37.7 54.1 35.9 37.2 64.0 12.6 200.8 33.9 43.6 46.7 34.5 80.2 68.7 99.2 141.5 80.4 84.3 69.5 131.4 97.9 88.3 11.5 107.9 51.1 113.5 62.1 87.8 10.4 10.4 11.0 11.7 9.9 11.0 11.1 11.1 11.3 11.2 11.2 11.1 63.4 16.0 13.1 1.0 67.0 235.3 141.0 82.9 132.1 10.1 73.1 91.4 7.6 17.2 36.1 20.2 4.2 75.4 64.7 8.2 41.1 39.7 20.3 34.0 39.3 62.1 18.7 41.9 1.5 31.2 77.1 63.7 5.6 37.8 76.2 23.5 27.5 13.4 45.3 11.8 2.2 23.9 59.0 16.6 141.2 12.8 51.6 36.9 108.5 1.9 23.9 24.5 35.0 2.5 2.8 41.3 11.0 40.3 46.0 111.3 8.3 24.1 24.0 18.3 6.6 89.5 70.5 89.6 76.4 87.4 253.5 40.2 66.7 27.8 27.9 118.1 OASL "OASL1, p59OASL, TRIP14" ENSG00000135114 "2'-5'-oligoadenylate synthetase like" Q15646 12 121017763-121039242 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.7;stomach 1: 22.3" "Cell type enhanced" "Detected in many" "dendritic cells: 54.1;Distal enterocytes: 82.3;Gastric mucus-secreting cells: 97.9;Paneth cells: 71.4;T-cells: 43.9;Urothelial cells: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 132.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 126.9;BJ hTERT+ SV40 Large T+ RasG12V: 66.2;GAMG: 35.3;hTEC/SVTERT24-B: 50.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001474 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA001474: AB_1079518" "unprognostic (2.39e-2)" "unprognostic (7.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (1.62e-2)" "unprognostic (6.22e-2)" "unprognostic (5.93e-3)" "prognostic unfavorable (9.20e-4)" "unprognostic (4.61e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (3.17e-2)" 2.3 0.8 0.7 4.2 0.8 35.7 2.4 0.7 0.8 3.3 0.6 7.5 2.7 0.5 0.5 4.0 0.7 3.6 1.1 0.6 0.5 2.3 11.8 11.9 3.6 1.4 0.7 0.4 0.7 0.1 0.6 1.4 1.4 0.5 3.4 0.2 4.1 0.4 0.4 0.9 2.0 1.3 3.3 5.3 22.3 2.1 1.1 3.3 1.1 0.6 1.7 7.8 1.4 0.9 2.6 0.6 0.2 0.9 1.0 1.6 0.1 0.2 0.9 126.9 66.2 0.3 13.0 0.6 4.0 0.1 35.3 6.4 0.1 0.9 7.2 25.2 0.1 0.1 13.8 0.0 0.7 0.2 1.8 0.8 0.6 50.7 0.1 0.3 0.3 1.0 0.1 5.3 1.1 1.7 0.1 3.1 0.1 4.5 3.7 0.1 0.2 1.4 0.1 13.7 0.1 0.2 1.1 0.6 18.5 0.1 0.4 1.7 0.1 0.7 1.2 2.1 0.2 4.9 10.1 0.3 19.9 1.3 0.4 12.3 29.6 65.8 53.1 32.5 14.3 2.5 36.2 62.1 8.9 0.8 9.9 38.5 132.8 20.3 23.5 0.5 27.8 33.2 0.7 0.8 0.7 0.8 0.6 0.5 1.4 0.7 1.4 3.3 1.1 0.9 28.6 0.0 4.2 0.7 4.6 2.2 5.0 2.7 1.8 0.0 3.3 4.7 0.6 1.5 3.9 0.0 0.0 0.2 54.1 82.3 0.0 2.5 6.6 2.0 0.6 4.5 1.8 0.8 0.2 3.8 1.3 2.4 97.9 2.8 11.4 1.0 2.2 4.5 12.6 0.0 0.2 30.7 4.1 3.1 7.2 3.4 0.3 16.7 0.0 1.0 6.0 0.0 9.2 0.0 0.0 12.7 71.4 0.0 14.3 2.2 2.4 0.3 3.8 0.0 0.0 0.7 2.8 2.4 0.1 14.6 1.0 0.1 43.9 0.2 5.1 96.3 ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 29.0;lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.5;Early spermatids: 5.6;Erythroid cells: 14.1;Extravillous trophoblasts: 9.9;Plasma cells: 6.3;Spermatogonia: 6.5" "Cancer enhanced" "Detected in many" "testis cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027439, HPA027450" Approved Supported Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027439: , HPA027450: AB_10602041" "unprognostic (3.28e-1)" "unprognostic (4.42e-3)" "prognostic favorable (1.74e-5)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (3.77e-3)" "prognostic unfavorable (3.69e-4)" "unprognostic (3.86e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-2)" "unprognostic (1.25e-10)" "unprognostic (4.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" 0.4 0.6 0.2 3.5 0.1 29.0 1.1 0.6 0.2 0.6 0.0 3.4 1.7 0.6 0.1 2.7 0.3 0.4 0.2 0.1 0.2 0.5 0.6 0.6 6.7 0.3 0.0 0.5 0.3 0.3 0.3 1.9 0.2 0.4 4.0 1.0 0.6 0.1 0.5 2.0 2.3 0.9 0.0 2.0 1.0 5.2 0.2 11.6 0.3 0.1 7.7 0.9 1.0 0.3 19.3 20.8 33.0 21.7 0.8 2.7 31.8 13.5 12.2 38.9 40.0 25.8 10.7 44.2 11.6 8.5 17.8 25.9 48.9 16.9 33.8 19.0 28.1 53.2 30.2 25.8 0.2 71.9 29.2 1.4 0.8 38.1 4.3 2.7 11.7 27.6 63.0 20.9 12.8 14.4 56.9 34.0 73.1 11.7 29.5 60.2 51.3 43.1 6.8 25.0 18.5 15.6 31.0 18.8 10.3 30.5 10.2 28.7 5.4 15.8 22.5 24.9 34.0 10.9 31.1 54.4 15.6 52.6 19.5 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.4 0.4 0.6 0.8 0.1 0.3 0.4 3.4 0.2 0.0 1.2 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.3 0.6 0.0 0.0 0.3 1.7 0.9 0.3 0.4 1.2 0.7 0.7 1.1 0.5 0.0 0.1 0.0 0.0 5.5 0.7 1.2 0.0 0.3 5.6 0.5 0.6 0.5 0.0 14.1 0.7 0.2 9.9 0.7 0.5 0.6 0.0 2.8 0.0 0.2 2.9 0.0 0.7 1.3 0.0 0.3 0.4 3.8 0.6 0.6 0.0 1.0 0.3 0.2 0.0 0.5 0.5 0.2 0.8 0.4 6.3 0.2 0.2 3.9 0.1 0.9 0.0 0.6 0.7 4.1 6.5 2.5 1.1 1.8 1.1 0.9 3.7 0.4 OSGIN2 "C8orf1, hT41" ENSG00000164823 "Oxidative stress induced growth inhibitor family member 2" Q9Y236 8 89901849-89927888 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 246.6;Granulosa cells: 144.4;Late spermatids: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 22.2" "Cell line enhanced" "Detected in all" "SK-BR-3: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028515, HPA050595" Approved Approved Nucleoli NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA028515: AB_10602014, HPA050595: AB_2681186" "unprognostic (3.29e-2)" "unprognostic (1.15e-1)" "unprognostic (7.09e-2)" "unprognostic (4.32e-3)" "unprognostic (1.42e-3)" "unprognostic (3.26e-2)" "prognostic unfavorable (3.91e-6)" "prognostic unfavorable (2.93e-4)" "unprognostic (2.32e-1)" "unprognostic (2.22e-3)" "unprognostic (4.38e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.66e-1)" "unprognostic (1.09e-1)" "unprognostic (7.25e-2)" 19.2 7.6 9.6 8.6 9.3 51.9 12.1 10.9 12.1 8.6 7.0 10.5 7.9 18.4 5.7 8.3 5.9 16.3 14.8 10.6 17.9 17.1 18.5 16.4 10.8 12.4 11.4 17.8 7.9 33.2 9.8 7.0 12.5 10.0 8.9 12.9 7.4 7.8 15.2 5.2 7.1 21.1 14.9 9.3 6.0 23.1 10.2 8.9 14.1 18.8 10.0 11.0 4.7 18.3 32.1 30.6 7.9 16.2 17.5 14.0 9.9 23.5 49.9 21.7 22.2 14.3 29.6 21.9 45.7 13.0 26.1 11.6 16.0 18.8 34.6 33.3 11.7 34.2 11.7 8.0 31.9 17.0 20.4 16.1 23.2 24.5 22.6 20.9 28.6 28.7 19.7 38.3 16.2 24.8 29.7 11.7 4.4 33.6 16.7 13.1 11.5 18.6 33.2 24.2 7.1 18.1 17.3 149.6 29.5 12.9 30.1 27.9 20.2 23.2 20.2 20.1 22.2 35.0 32.2 24.2 38.6 21.9 17.5 22.2 1.6 7.5 1.9 1.2 2.7 3.5 2.8 1.7 1.8 2.0 2.3 2.6 12.4 2.5 1.5 1.3 3.1 1.6 9.6 9.3 10.9 12.1 10.6 17.9 12.4 11.4 12.5 14.9 10.2 18.3 9.8 64.1 14.8 49.3 10.4 6.0 6.9 9.2 2.8 9.0 13.3 6.7 13.9 17.2 12.5 7.3 2.1 6.8 10.6 4.2 9.8 13.6 246.6 11.6 10.8 7.4 9.6 8.6 14.9 16.0 8.4 13.7 2.0 14.1 17.1 144.4 13.6 17.6 16.5 3.3 14.9 3.8 20.3 19.1 9.4 216.8 12.5 15.7 7.2 9.4 13.3 25.3 5.2 7.5 7.8 14.0 3.4 12.4 6.1 7.2 3.0 14.8 15.2 6.0 13.1 18.9 9.0 28.9 8.8 4.5 4.3 1.6 8.3 3.0 5.1 7.6 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439075-23442377 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 149.0;Langerhans cells: 219.1;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.1;HaCaT: 36.5;SiHa: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: AB_2676049, HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 13.0 11.7 8.0 10.2 8.4 60.4 10.3 9.5 10.2 8.4 8.4 8.7 6.8 10.2 6.8 7.8 11.2 9.7 43.4 8.7 9.0 19.7 7.6 19.7 14.4 8.3 8.0 13.6 6.9 19.4 8.0 12.1 7.6 8.8 7.6 5.9 6.7 7.6 29.4 20.9 8.2 9.4 8.4 13.7 22.9 7.5 9.2 6.8 13.3 22.6 12.5 11.9 7.6 9.2 4.8 2.3 2.4 1.1 9.3 4.6 3.2 1.9 4.2 4.4 4.0 0.9 38.1 2.2 4.1 2.4 1.5 36.5 2.5 4.5 2.9 17.4 7.1 0.1 5.7 1.5 8.0 0.4 3.2 4.8 19.4 1.3 6.1 3.9 1.5 2.2 0.5 15.1 2.5 2.3 1.5 1.4 1.9 2.7 1.3 2.4 10.8 2.2 5.8 4.0 1.1 2.6 23.4 4.1 11.3 6.3 1.7 3.3 2.7 2.5 3.7 7.0 0.8 7.6 15.0 1.1 3.8 1.5 1.0 2.5 0.5 1.0 0.3 0.6 0.3 0.7 0.5 0.3 0.3 1.2 0.4 0.6 1.3 0.0 1.9 0.2 1.3 0.2 8.0 8.4 9.5 10.2 8.7 9.0 8.3 8.0 7.6 8.4 9.2 9.2 17.3 67.3 11.5 3.3 55.9 32.0 7.1 5.0 13.6 20.1 12.3 9.1 149.0 7.2 4.9 5.5 2.1 3.3 9.6 47.2 11.7 6.0 8.0 35.0 44.5 25.6 6.0 13.5 4.3 7.1 3.2 20.8 47.4 33.8 5.7 10.4 16.4 10.1 51.0 53.8 4.8 77.9 10.2 68.2 219.1 7.6 6.5 105.7 33.8 8.4 9.3 33.8 10.3 4.0 6.5 10.1 16.3 13.2 50.0 7.7 8.0 25.1 9.8 26.2 6.6 82.2 19.4 7.2 4.7 15.1 30.5 7.9 16.5 7.5 24.3 10.9 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.0;pancreas: 65.1;urinary bladder: 75.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 185.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.3" "Group enriched" "Detected in many" 30 "dendritic cells: 15.1;granulocytes: 23.5;monocytes: 46.3" "Cell line enhanced" "Detected in some" "HEL: 13.8;HMC-1: 8.4;Karpas-707: 16.8;THP-1: 14.7;U-937: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.3" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" 9.8 2.0 0.5 4.4 0.8 42.0 1.5 0.8 0.7 7.7 0.4 13.4 9.3 7.3 1.8 23.0 3.9 2.0 2.0 0.5 0.7 1.0 0.7 4.8 2.9 0.8 0.9 2.1 65.1 0.1 0.3 3.8 0.8 10.7 9.2 0.1 1.6 34.1 0.5 5.9 9.0 6.0 0.7 13.0 2.8 2.6 0.6 2.0 0.4 0.3 3.2 75.5 8.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.2 0.1 1.1 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.1 3.3 0.0 0.4 0.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 7.4 0.0 0.0 10.8 11.9 0.0 20.4 0.0 0.4 0.0 0.0 5.9 0.9 0.0 0.0 23.5 0.0 46.3 15.1 0.0 8.2 0.5 0.8 0.8 0.7 0.5 0.7 0.8 0.9 0.8 0.7 0.6 1.0 0.1 3.2 4.2 0.7 15.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.1 8.9 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 18.5 0.3 2.0 0.1 0.9 0.5 0.0 185.4 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.0 5.1 2.4 0.2 0.0 22.5 0.0 1.0 7.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 36.0 0.0 0.0 0.1 0.7 0.0 0.0 0.4 3.4 0.0 0.1 0.1 0.9 0.0 1.8 0.5 0.3 0.0 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PHF12 "KIAA1523, PF1" ENSG00000109118 "PHD finger protein 12" Q96QT6 17 28905250-28951771 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 40.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021410, HPA021452" Approved Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA021410: AB_1855287, HPA021452: AB_2670708" "unprognostic (9.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-2)" "unprognostic (1.21e-2)" "unprognostic (2.81e-1)" "unprognostic (1.46e-2)" "unprognostic (1.69e-2)" "unprognostic (3.10e-2)" "unprognostic (8.73e-2)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "unprognostic (6.71e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.16e-2)" "unprognostic (3.11e-1)" "unprognostic (3.24e-1)" "unprognostic (1.08e-3)" 13.7 11.0 11.6 15.6 12.6 39.9 14.4 14.1 12.1 17.9 7.2 18.2 11.5 18.7 14.0 10.6 17.2 11.0 11.0 10.7 11.9 12.3 14.7 16.7 18.2 11.5 11.1 17.9 19.1 13.8 16.9 10.9 9.1 21.8 11.4 14.9 15.7 17.0 15.7 15.2 17.7 14.6 7.2 22.9 14.8 9.9 11.3 25.3 17.0 14.2 17.2 16.8 13.8 14.0 15.0 24.4 33.1 19.8 18.6 13.8 15.0 14.6 22.0 23.0 21.2 16.9 14.3 17.3 17.9 17.4 19.0 15.9 21.5 13.0 21.8 27.9 22.5 18.8 27.2 13.2 16.8 20.5 22.7 15.8 13.8 20.9 19.0 21.3 16.7 23.0 16.0 18.6 14.2 16.6 38.3 26.7 19.0 33.6 10.4 38.2 26.8 17.6 15.2 19.3 22.8 18.7 22.6 35.7 17.6 17.5 19.6 26.6 9.9 18.9 16.8 18.2 18.4 21.9 19.9 20.2 14.7 15.2 19.5 25.2 4.4 7.2 6.3 3.6 6.1 4.4 4.9 6.6 2.5 6.5 4.4 5.2 40.1 6.3 4.3 8.2 3.1 2.9 11.6 12.6 14.1 12.1 10.7 11.9 11.5 11.1 9.1 7.2 11.3 14.0 13.1 16.0 8.6 27.1 24.7 15.3 8.5 7.5 26.7 22.7 17.6 15.1 6.9 8.6 12.2 3.7 14.6 7.9 24.5 12.0 1.9 9.1 9.5 17.5 16.4 14.4 10.7 27.0 16.3 10.4 7.6 11.9 12.8 23.8 14.5 14.4 14.3 11.7 9.2 25.2 18.6 16.5 12.2 15.7 18.9 7.4 17.1 16.5 12.4 27.2 20.0 12.9 17.5 30.2 31.3 9.7 6.5 16.6 31.4 27.1 8.9 5.9 8.1 21.3 26.3 11.2 17.2 13.5 12.6 22.2 16.3 6.0 35.3 11.4 10.8 14.0 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.5;Suprabasal keratinocytes: 55.0;Urothelial cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 2.1 2.9 2.2 2.9 2.7 9.2 3.1 2.0 3.6 2.8 0.8 3.7 1.9 3.0 3.5 5.1 2.8 3.7 2.0 1.6 1.8 3.8 4.5 6.7 3.5 2.8 2.7 2.4 4.0 3.3 0.6 3.6 2.2 2.7 3.7 4.5 4.6 1.7 1.3 1.4 2.4 2.5 2.2 2.0 2.8 2.6 2.3 4.0 4.4 1.3 4.7 10.3 1.9 5.8 14.5 8.3 9.1 5.0 2.6 2.8 7.0 3.7 5.7 7.4 7.3 9.2 6.5 6.6 2.9 2.9 9.0 5.8 14.3 11.4 12.6 6.1 9.5 5.5 11.0 5.8 4.5 8.8 2.9 3.3 8.1 10.0 16.0 2.4 5.0 5.2 6.4 7.0 5.1 9.2 9.0 3.4 4.7 5.5 8.2 3.0 12.4 10.7 5.6 9.4 6.2 9.4 6.9 6.8 14.4 8.7 6.6 7.4 4.2 6.2 2.4 14.0 7.3 5.4 7.2 9.9 9.4 5.6 7.9 22.9 3.8 4.3 2.6 6.3 3.7 3.0 4.1 2.6 3.9 2.1 3.8 2.9 5.2 1.8 8.6 2.6 4.1 2.7 2.2 2.7 2.0 3.6 1.6 1.8 2.8 2.7 2.2 2.2 2.3 5.8 6.4 19.2 83.5 6.8 7.2 29.6 41.9 10.6 13.6 3.5 13.2 10.5 6.9 5.7 20.1 3.7 0.0 6.3 7.4 8.4 11.7 7.6 5.4 30.8 9.8 7.9 10.7 9.3 2.2 5.8 10.2 12.7 17.9 45.6 33.6 3.0 3.6 4.4 8.8 3.3 2.0 5.0 2.0 8.4 43.4 4.4 3.1 18.1 28.4 2.8 3.6 4.2 4.1 1.0 7.7 8.3 5.1 3.0 5.5 32.0 2.1 6.6 19.8 3.0 13.1 10.6 16.3 2.7 3.7 35.5 55.0 28.0 11.7 2.9 6.0 62.2 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 219.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 368.2;Suprabasal keratinocytes: 228.6;Urothelial cells: 455.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 321.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 321.3" "Cell line enhanced" "Detected in all" "HEL: 219.9;HMC-1: 391.5;K-562: 192.7;U-698: 735.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 152.8 14.4 8.5 42.3 8.6 219.0 46.2 10.5 10.7 82.9 10.0 45.8 39.2 46.3 2.6 201.5 66.4 52.6 65.4 7.9 11.6 27.0 58.0 49.8 38.5 15.1 12.2 60.4 20.4 3.4 14.8 28.9 12.8 22.5 17.8 8.2 41.1 7.5 36.3 109.8 44.4 38.1 12.3 61.7 40.3 10.7 11.6 26.6 22.7 5.8 26.8 101.6 113.3 12.1 19.1 7.9 12.1 6.7 27.2 14.5 141.9 6.7 20.3 13.5 21.5 28.3 26.2 38.3 10.4 8.0 30.2 21.7 12.7 20.1 12.3 174.4 8.4 219.9 8.7 37.0 27.9 3.8 391.5 49.0 24.5 12.4 8.3 14.9 4.0 9.2 192.7 59.7 2.2 5.0 12.3 19.9 22.7 35.4 12.1 29.7 22.0 45.7 3.9 114.4 58.8 11.9 14.7 1.7 3.8 27.9 3.2 6.5 7.4 7.8 23.3 35.6 8.5 28.0 15.9 735.7 3.4 55.3 8.1 321.3 8.0 113.5 60.3 7.3 77.7 7.1 53.4 53.8 6.3 5.2 47.1 36.9 61.7 39.8 4.2 1.9 41.3 42.1 8.5 8.6 10.5 10.7 7.9 11.6 15.1 12.2 12.8 12.3 11.6 12.1 41.1 22.4 16.0 2.9 35.1 127.8 166.5 63.3 26.7 4.9 9.6 5.3 36.0 18.6 37.6 9.2 0.0 36.5 55.0 50.4 5.9 40.6 4.8 40.3 125.8 33.3 37.1 368.2 2.4 17.2 121.8 67.4 26.0 92.0 49.3 27.5 11.0 33.8 53.6 15.2 2.2 12.4 44.7 44.3 47.4 12.4 8.1 53.9 44.4 4.7 72.3 7.6 112.3 1.0 0.9 60.7 34.2 3.0 190.1 109.6 51.1 17.2 12.9 1.7 0.0 34.2 41.3 14.5 33.9 92.8 228.6 80.7 118.0 1.1 7.8 455.2 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLAGL2 ZNF900 ENSG00000126003 "PLAG1 like zinc finger 2" Q9UPG8 20 32192504-32207743 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.2" "Cell type enhanced" "Detected in many" "Early spermatids: 56.7;Glandular and luminal cells: 47.7;Late spermatids: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "intermediate monocyte: 18.3;non-classical monocyte: 34.8" "Lineage enriched" "Detected in many" 15 "monocytes: 34.8" "Cell line enhanced" "Detected in all" "CACO-2: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005900 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA005900: AB_1079629" "unprognostic (9.40e-2)" "unprognostic (1.67e-1)" "unprognostic (6.95e-3)" "unprognostic (1.09e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-3)" "unprognostic (8.63e-2)" "unprognostic (8.97e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-2)" "unprognostic (2.26e-1)" "unprognostic (3.08e-1)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (7.90e-2)" "unprognostic (1.09e-1)" 4.4 3.2 4.4 6.6 5.2 32.2 4.6 5.0 5.0 4.8 7.4 7.8 10.4 6.0 5.2 12.8 9.4 4.1 5.2 5.1 4.0 4.9 4.3 6.6 7.7 4.3 4.1 7.7 6.0 8.5 5.5 3.9 3.6 5.3 8.0 13.0 6.8 5.4 10.2 7.5 12.9 7.2 3.7 6.2 7.2 16.4 4.2 8.9 4.8 8.3 10.7 5.6 6.1 4.2 19.4 10.9 28.5 10.4 10.4 8.0 17.8 7.5 11.9 16.0 14.5 82.3 9.5 19.8 10.1 7.8 22.4 18.6 35.7 17.3 21.0 11.9 16.1 80.3 9.4 39.8 12.7 35.5 17.0 9.7 15.1 12.9 9.1 7.5 11.7 20.7 28.7 17.5 8.5 10.8 39.2 24.4 13.4 14.8 12.4 25.0 36.8 12.6 6.9 14.6 12.9 14.2 18.5 9.9 16.1 16.5 14.9 42.8 8.8 19.3 20.5 14.0 15.5 47.5 28.5 25.1 11.2 73.5 12.1 2.2 3.6 0.9 0.7 18.3 1.4 1.4 1.0 1.5 2.2 1.0 1.2 0.7 0.9 0.5 34.8 0.6 0.8 2.5 4.4 5.2 5.0 5.0 5.1 4.0 4.3 4.1 3.6 3.7 4.2 4.2 4.3 12.8 21.1 2.0 6.0 7.5 13.5 6.2 10.8 7.4 8.6 6.5 4.2 2.8 12.2 1.8 31.3 3.2 8.1 13.1 3.9 3.8 56.7 26.1 9.1 5.2 10.7 10.3 4.5 5.2 3.1 5.7 8.2 47.7 2.5 6.4 7.1 3.8 6.0 3.3 3.8 12.4 2.0 8.9 7.8 159.8 2.5 11.9 0.0 4.7 11.1 6.3 0.0 1.5 4.9 6.2 8.9 7.2 7.9 15.0 29.3 3.4 6.8 21.3 6.6 7.1 4.1 11.8 10.8 21.2 11.6 4.1 7.4 6.2 16.7 21.7 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.6;lymphoid tissue: 14.4;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 65.9;Late spermatids: 87.5;Spermatocytes: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.0 1.1 0.4 4.9 0.5 22.6 2.0 0.2 0.7 0.9 0.1 3.5 2.8 1.5 0.6 3.2 1.3 1.1 0.5 0.5 0.6 0.6 0.8 0.9 7.4 0.5 0.5 1.0 0.4 0.6 0.2 3.6 0.4 0.9 4.3 2.1 0.9 0.9 0.1 2.3 2.9 1.8 0.4 1.6 2.0 22.6 0.6 14.4 0.9 0.7 7.3 1.3 1.4 0.4 26.1 12.1 44.3 22.9 1.5 4.2 20.1 24.9 17.6 32.4 33.3 17.0 26.1 34.9 9.0 13.9 26.3 16.7 31.6 19.9 49.6 27.4 13.1 31.6 20.0 16.0 0.5 45.2 35.9 1.4 2.0 29.7 13.6 5.9 25.3 26.3 37.5 45.2 27.6 18.2 69.9 20.1 20.7 26.3 13.6 36.0 30.9 12.1 10.8 16.4 24.4 20.0 15.8 14.2 7.6 18.7 11.5 19.3 11.0 25.3 24.4 17.4 31.4 23.1 27.4 49.0 13.0 33.7 28.7 0.0 0.1 0.4 0.4 0.2 0.3 0.1 0.5 0.5 0.2 0.2 0.1 0.6 0.0 0.4 0.1 0.1 1.2 0.2 0.4 0.5 0.2 0.7 0.5 0.6 0.5 0.5 0.4 0.4 0.6 0.4 1.6 0.0 0.6 0.0 1.6 1.7 0.9 1.7 1.2 1.8 1.0 0.9 0.9 0.0 0.6 1.8 0.0 6.0 1.9 2.0 0.0 0.6 65.9 4.7 1.0 1.0 2.4 19.6 0.8 0.4 12.9 1.6 4.1 2.0 1.3 7.5 0.4 0.5 3.7 0.0 0.8 3.3 6.1 1.3 0.6 87.5 2.8 1.5 0.0 1.0 1.2 1.1 1.0 1.0 1.2 0.1 0.5 0.4 8.7 0.7 0.5 0.6 3.7 0.8 0.0 0.4 3.6 53.5 13.4 6.8 0.9 3.8 2.1 0.8 4.5 1.7 POC1B-GALNT4 ENSG00000259075 "POC1B-GALNT4 readthrough" 12 89519408-89526262 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "B-cells: 2.5;Basal squamous epithelial cells: 3.4;Club cells: 3.1;Erythroid cells: 3.0;Gastric mucus-secreting cells: 2.6;Glandular and luminal cells: 2.5;Respiratory ciliated cells: 2.9;Squamous epithelial cells: 1.8;T-cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 10.2" HPA076116 Approved "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA076116: AB_2686778" "unprognostic (4.91e-2)" "unprognostic (5.00e-2)" "unprognostic (1.26e-1)" "unprognostic (2.77e-6)" "unprognostic (7.99e-2)" "unprognostic (1.55e-2)" "unprognostic (2.26e-1)" "unprognostic (2.64e-1)" "unprognostic (7.67e-2)" "unprognostic (2.44e-1)" "unprognostic (7.72e-3)" "unprognostic (1.95e-1)" "unprognostic (1.61e-4)" "unprognostic (7.65e-3)" "unprognostic (1.05e-1)" "unprognostic (2.15e-2)" "unprognostic (5.16e-2)" 0.9 0.3 0.2 1.6 0.5 2.8 0.4 0.7 0.5 0.5 0.0 0.8 1.7 1.1 0.0 0.5 1.1 1.3 0.4 0.4 0.6 0.5 0.4 0.5 0.8 0.5 0.4 0.8 0.4 0.5 0.4 0.5 0.5 0.5 1.0 1.3 1.4 0.1 0.8 0.5 0.9 0.4 0.2 0.7 2.0 0.9 0.6 0.4 0.7 0.2 0.5 0.6 0.5 0.6 1.1 1.0 2.2 10.2 0.3 0.2 0.6 0.4 0.9 1.4 1.0 0.9 0.8 0.9 0.2 1.1 0.9 0.8 2.1 0.7 1.5 2.2 1.3 1.6 1.3 1.8 0.0 1.3 1.8 0.0 0.6 1.5 0.8 1.4 1.2 1.6 1.1 0.6 0.4 0.6 1.3 1.5 0.7 2.1 3.9 1.5 1.4 2.6 0.8 1.5 0.9 1.1 1.2 1.0 0.5 0.7 2.0 1.5 1.4 1.5 0.8 0.7 1.2 0.9 1.7 1.2 1.1 1.1 1.4 1.1 0.8 0.8 0.9 0.9 1.5 0.3 0.6 0.7 0.6 0.7 0.7 0.8 1.7 0.8 1.1 0.4 0.7 0.6 0.2 0.5 0.7 0.5 0.4 0.6 0.5 0.4 0.5 0.2 0.6 0.6 0.3 0.0 0.6 0.0 2.5 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.6 0.1 0.0 3.0 0.0 0.0 0.0 0.3 2.6 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 2.9 0.0 0.0 0.0 0.7 0.0 0.0 1.8 0.0 0.0 1.8 0.1 0.2 0.1 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 51.3;Spermatogonia: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004375: AB_675487, HPA046524: AB_2679684" "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 5.6 5.1 3.2 9.2 3.7 26.3 6.3 4.5 3.8 7.6 2.5 8.9 5.4 8.4 0.4 10.7 6.5 2.1 5.8 2.7 2.7 6.5 6.4 9.5 11.2 5.1 3.7 7.1 7.9 2.3 4.7 5.9 4.1 6.1 2.2 1.9 7.4 2.6 5.6 9.2 10.1 2.3 3.5 12.8 6.2 13.3 4.1 11.0 9.8 1.5 5.2 5.9 7.7 4.4 52.1 77.9 27.9 22.4 3.0 2.8 45.6 34.0 9.6 30.0 34.9 42.4 39.2 84.6 19.4 7.1 13.9 45.1 27.4 25.1 6.8 64.4 145.0 66.1 73.0 54.6 3.7 67.0 57.7 6.4 7.1 26.1 6.5 6.0 14.2 58.2 77.4 54.3 9.1 40.6 92.2 110.6 48.7 25.3 55.4 105.4 62.2 67.7 7.4 44.9 39.3 38.6 33.0 35.9 8.8 10.1 21.1 50.7 17.4 21.4 70.7 22.0 56.5 60.0 91.3 76.3 21.2 66.9 20.8 1.3 4.3 1.5 4.3 5.6 4.0 6.0 4.0 3.5 3.9 5.4 4.0 3.9 0.6 4.2 6.9 7.1 3.1 4.0 3.2 3.7 4.5 3.8 2.7 2.7 5.1 3.7 4.1 3.5 4.1 4.4 3.5 3.2 3.9 0.7 8.7 6.4 2.3 3.5 3.4 4.0 4.3 5.3 3.4 2.8 3.8 3.7 6.2 19.2 3.8 12.2 0.0 4.8 1.9 2.8 1.6 3.4 7.2 15.2 1.2 4.0 15.0 4.1 3.1 3.0 0.0 9.5 1.1 2.2 15.1 0.0 0.9 7.4 0.0 5.7 5.3 1.9 3.1 5.8 5.4 1.0 4.8 1.2 6.2 1.5 2.2 4.7 51.3 5.3 10.6 2.8 6.3 2.8 3.0 4.3 0.0 3.5 4.0 11.5 25.6 5.5 5.3 7.7 5.4 3.4 14.3 1.3 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 21.0;Spermatogonia: 24.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 0.9 0.9 0.5 5.1 0.3 18.2 3.0 0.5 0.6 2.1 0.0 3.8 2.5 2.5 0.7 3.7 1.0 0.9 0.6 0.2 0.2 0.7 3.1 1.2 5.1 0.2 0.4 1.0 0.8 0.7 0.5 3.0 0.2 1.4 4.5 3.0 1.0 0.7 0.5 3.5 3.6 2.3 0.3 1.5 2.1 4.1 0.2 5.5 0.9 0.9 6.2 1.4 1.9 0.6 37.2 18.6 34.3 16.3 1.7 9.9 18.2 20.4 10.4 31.9 36.7 19.3 27.5 23.6 11.6 11.6 17.5 22.3 35.3 12.8 36.9 27.4 19.6 35.4 20.6 23.9 0.8 41.2 14.6 2.8 0.8 18.5 2.9 4.1 19.0 30.5 30.9 14.3 31.6 32.7 43.6 28.4 20.2 30.9 42.6 35.9 31.7 21.0 11.6 20.6 24.8 14.3 20.5 11.9 6.7 16.5 24.5 15.8 6.7 5.3 38.5 21.4 16.9 10.7 22.7 52.7 9.8 30.1 20.9 0.0 0.0 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.0 0.2 0.0 0.9 0.0 0.2 0.7 0.1 0.5 0.3 0.5 0.6 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 2.0 3.2 0.5 4.2 2.4 4.8 2.1 1.9 2.2 0.8 1.5 1.1 1.2 1.5 1.3 0.0 0.0 9.1 1.0 2.2 0.0 1.3 1.2 0.8 2.6 1.5 1.2 21.0 9.5 1.5 10.6 2.7 1.1 1.5 0.0 4.3 5.0 5.5 5.5 0.0 11.9 2.8 0.0 1.9 1.6 0.8 1.5 1.1 1.8 7.5 1.0 2.0 4.1 12.1 11.5 0.8 0.5 3.0 5.7 1.9 1.1 1.2 0.9 3.1 0.0 2.1 7.4 5.3 24.4 6.0 3.7 3.4 1.7 1.8 4.7 1.5 POLE3 "CHARAC17, CHRAC17, CHRAC2, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410675 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047945 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA047945: AB_2680218" "unprognostic (9.55e-2)" "unprognostic (3.39e-3)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.04e-2)" "unprognostic (1.60e-2)" "unprognostic (1.10e-1)" "unprognostic (4.59e-3)" "unprognostic (2.31e-3)" "unprognostic (1.75e-2)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" 25.4 32.9 20.3 34.9 20.9 113.5 31.7 24.7 24.2 25.8 17.3 29.6 25.4 25.2 26.0 39.7 28.2 18.0 26.4 21.2 19.7 23.6 38.1 23.7 53.6 21.9 19.6 22.6 27.4 26.7 11.2 26.6 21.5 23.0 32.8 16.4 27.2 22.8 79.1 37.3 26.3 27.8 20.8 33.0 24.9 41.1 19.8 55.1 21.8 56.4 56.7 28.5 24.8 21.5 85.0 103.3 71.2 107.6 39.8 35.3 62.5 110.3 56.0 122.1 95.6 96.5 75.0 305.5 66.9 65.0 74.5 141.4 140.3 121.4 112.0 58.8 84.7 158.9 97.7 99.5 42.4 333.5 92.2 40.5 82.2 106.3 135.5 44.3 86.0 152.7 225.7 165.6 85.9 215.1 230.6 178.4 92.1 180.7 184.8 232.4 296.3 171.8 53.4 79.8 153.8 88.7 160.2 100.0 89.4 43.0 149.7 148.1 71.3 90.0 122.3 115.2 191.2 86.0 301.5 407.4 82.2 193.5 110.1 77.4 85.4 90.4 83.8 87.0 104.2 86.3 78.9 79.8 83.3 82.4 84.8 79.3 17.5 77.4 71.6 83.6 102.0 135.2 20.3 20.9 24.7 24.2 21.2 19.7 21.9 19.6 21.5 20.8 19.8 21.5 37.2 38.5 30.2 2.0 61.4 93.8 30.8 37.0 66.0 15.0 51.9 49.9 43.6 21.5 35.8 31.3 6.2 60.7 73.9 28.9 43.0 35.7 5.1 45.4 53.7 33.9 24.6 101.6 4.7 45.4 62.5 37.6 22.4 44.1 57.5 41.4 25.7 43.1 49.3 13.5 3.9 36.9 28.5 36.5 66.4 16.4 35.8 44.7 40.9 1.9 60.3 29.9 48.4 3.5 3.6 37.6 13.9 42.5 67.8 36.0 18.3 34.4 35.5 18.3 13.1 47.9 45.7 40.2 93.1 87.6 94.9 34.9 65.5 36.3 42.5 22.6 POLR1F "A43, RPA43, TWISTNB" ENSG00000105849 "RNA polymerase I subunit F" Q3B726 7 19695461-19709037 "Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 21.6;Cardiomyocytes: 23.1;Cytotrophoblasts: 40.3;dendritic cells: 24.9;Extravillous trophoblasts: 34.1;Hofbauer cells: 34.7;Macrophages: 16.7;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019071, HPA022416" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" Nucleoplasm "HPA019071: AB_1858465, HPA022416: AB_1858466" "unprognostic (5.66e-3)" "unprognostic (3.43e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.98e-3)" "unprognostic (1.85e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.16e-1)" "unprognostic (5.87e-2)" "unprognostic (2.03e-1)" "unprognostic (5.02e-2)" "unprognostic (4.93e-2)" "unprognostic (6.16e-2)" "unprognostic (1.23e-1)" "unprognostic (9.06e-2)" "unprognostic (4.95e-3)" "unprognostic (2.96e-1)" 8.6 7.9 5.8 8.0 6.4 17.2 10.2 6.1 9.2 8.9 5.6 7.3 5.6 11.9 5.1 9.5 6.6 6.2 7.8 6.2 6.8 8.0 8.7 6.3 10.5 6.1 6.8 8.8 7.5 9.1 2.7 10.8 6.1 9.7 7.0 3.2 6.1 8.9 7.1 7.6 5.3 11.8 6.6 7.8 5.8 6.2 6.5 8.6 8.7 8.3 12.9 12.2 4.6 7.6 28.0 20.9 15.1 22.6 17.1 21.1 11.7 15.7 11.8 17.9 20.7 17.2 23.9 31.0 44.6 19.6 22.7 24.6 30.9 29.2 33.3 9.9 23.7 28.8 15.9 13.3 26.2 59.4 20.0 19.2 20.3 19.7 23.4 12.1 29.7 21.3 45.0 27.2 26.1 10.1 32.9 55.3 39.3 28.9 23.4 26.3 26.0 32.6 29.7 14.2 10.9 16.4 14.3 38.3 20.0 24.6 15.5 52.5 25.0 37.0 19.8 34.5 38.4 34.4 22.8 77.5 25.0 86.9 55.5 5.7 4.5 1.4 7.9 6.0 12.0 12.5 9.4 10.5 7.0 13.0 10.7 12.6 0.4 17.4 5.9 9.0 9.3 5.8 5.8 6.4 6.1 9.2 6.2 6.8 6.1 6.8 6.1 6.6 6.5 7.6 21.6 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 40.3 24.9 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 34.1 10.3 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 16.6 3.0 0.0 0.0 0.0 POM121 "DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A" ENSG00000196313 "POM121 transmembrane nucleoporin" Q96HA1 7 72879365-72951440 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 98.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB003710, HPA043809, HPA049817" Approved Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" "CAB003710: , HPA043809: AB_2678680, HPA049817: AB_2680896" "unprognostic (2.33e-1)" "unprognostic (3.05e-2)" "unprognostic (9.71e-2)" "unprognostic (5.86e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "unprognostic (1.40e-1)" "unprognostic (6.38e-2)" "unprognostic (7.07e-3)" "unprognostic (3.08e-2)" "unprognostic (3.84e-2)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (3.66e-2)" "unprognostic (2.39e-1)" "unprognostic (7.43e-3)" "unprognostic (2.40e-1)" 25.4 20.4 10.3 18.8 10.1 44.7 21.0 7.2 14.3 18.3 3.4 19.5 21.6 19.6 9.4 20.1 18.7 13.6 16.0 11.9 9.7 16.6 23.5 17.4 21.3 6.8 8.5 23.8 25.5 16.1 21.4 17.0 6.4 19.2 12.1 17.5 19.3 11.2 25.7 21.6 22.8 13.0 2.3 22.9 21.8 18.7 8.8 17.8 20.0 16.0 17.1 18.8 18.1 9.1 49.6 35.4 43.5 98.0 23.0 18.8 36.0 34.6 29.2 33.8 29.3 63.0 30.6 67.7 11.0 30.1 37.5 37.0 43.5 33.6 37.6 59.2 86.5 50.6 36.6 42.4 23.5 106.1 61.8 24.8 23.3 44.9 41.0 21.9 25.5 38.5 141.2 49.3 33.7 37.8 63.7 67.0 45.5 27.4 42.3 57.4 33.8 57.1 17.2 42.8 61.7 54.3 30.3 57.3 31.1 28.8 48.1 55.0 36.2 60.2 36.8 48.0 70.5 58.8 58.8 96.0 35.2 66.6 61.0 0.0 0.8 1.4 1.7 0.5 1.0 1.0 1.1 1.3 0.9 1.1 0.9 1.4 0.9 1.6 1.4 1.5 0.6 1.1 10.3 10.1 7.2 14.3 11.9 9.7 6.8 8.5 6.4 2.3 8.8 9.1 31.8 38.5 28.9 33.0 28.6 25.2 10.1 17.5 29.0 34.6 19.5 19.7 4.4 20.0 19.9 18.4 98.0 17.1 30.6 19.7 5.9 12.3 13.2 14.6 24.7 18.3 18.0 30.7 55.6 17.1 13.2 19.2 32.1 21.3 16.5 31.1 17.2 24.9 16.2 40.4 58.9 21.7 16.2 18.9 21.7 6.3 14.9 23.3 19.6 23.4 13.8 18.2 32.0 30.2 38.6 21.8 14.1 17.7 37.6 22.2 19.1 8.4 17.6 26.6 13.1 27.0 17.6 19.2 13.1 29.6 31.0 19.4 27.9 24.7 23.2 21.9 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023586-75117462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 71.4;granulocytes: 153.5;monocytes: 71.6" "Cell line enhanced" "Detected in all" "Karpas-707: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA 25000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 11.1 19.1 7.4 10.8 8.8 19.7 10.9 8.3 8.4 9.7 8.7 11.5 9.7 8.3 9.8 19.0 10.8 8.4 8.5 6.9 8.0 17.2 13.1 10.8 16.4 9.2 8.8 9.0 16.5 21.3 9.3 9.2 8.5 13.0 9.4 7.6 13.9 7.6 11.9 9.0 9.9 5.4 8.0 18.8 11.3 9.7 8.6 12.1 11.2 5.9 12.3 11.2 10.0 10.3 15.6 28.8 11.8 9.2 7.0 6.4 10.1 15.5 7.0 20.3 15.9 16.9 41.2 17.7 26.8 7.8 12.5 15.9 19.2 25.6 10.4 62.6 23.4 31.1 18.8 18.3 19.9 18.3 38.7 8.6 16.7 21.0 32.3 8.2 16.6 25.8 21.3 133.2 14.8 30.0 10.9 28.1 18.9 32.9 13.4 18.2 23.0 38.3 15.3 22.2 28.3 8.3 22.9 31.3 34.6 13.4 38.7 23.4 9.4 20.6 14.4 10.5 27.6 40.5 29.3 30.1 12.7 45.9 23.7 47.2 23.1 153.5 11.6 65.6 19.4 15.7 10.6 13.0 17.6 8.6 11.7 14.5 139.7 18.5 71.6 71.4 12.7 15.8 7.4 8.8 8.3 8.4 6.9 8.0 9.2 8.8 8.5 8.0 8.6 10.3 10.2 16.0 5.2 2.9 10.5 3.8 6.1 8.5 8.6 2.8 9.6 8.8 4.2 4.3 9.7 9.2 0.0 17.5 16.0 19.7 25.4 17.3 1.0 8.2 4.3 10.7 4.2 11.6 1.4 15.3 13.6 7.4 14.8 8.3 12.0 9.9 10.4 5.3 20.0 8.4 1.7 10.9 12.2 15.7 6.7 2.5 4.4 15.5 14.2 2.8 20.0 4.7 8.2 2.5 4.6 18.0 38.1 5.3 33.9 6.5 10.5 19.0 12.2 10.7 6.6 6.3 8.7 6.9 15.7 10.8 4.0 10.9 9.7 11.3 11.7 13.6 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.9" "Cell type enhanced" "Detected in all" "Early spermatids: 446.2;Late spermatids: 565.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 380000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Plasma membrane" "HPA029209: AB_2672951" "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 22.7 19.2 14.0 22.2 16.5 142.9 23.5 27.0 22.4 22.4 3.3 36.6 36.8 28.0 19.3 25.7 17.3 20.1 36.8 16.7 24.4 42.5 51.2 20.3 24.4 18.2 16.3 16.2 25.5 36.8 14.3 22.1 20.0 29.9 36.0 51.0 31.5 23.0 78.9 21.9 37.3 26.5 15.3 20.4 23.2 54.5 16.4 31.1 24.3 76.6 26.2 21.4 17.8 23.1 129.7 28.6 24.4 20.9 36.5 33.6 31.1 34.8 40.7 25.3 23.8 16.3 37.2 77.1 32.4 39.6 18.7 28.1 25.5 35.9 44.0 70.1 14.4 47.6 19.5 25.7 30.6 54.7 32.6 28.6 42.1 29.7 40.4 29.5 25.1 38.7 26.9 59.6 31.3 56.5 71.5 12.8 23.0 25.8 23.9 25.3 56.5 25.0 30.4 61.2 41.2 31.0 36.1 41.7 30.1 22.2 42.0 23.5 35.1 52.4 52.0 23.3 25.0 46.1 28.1 89.9 24.0 21.2 27.1 5.4 1.0 3.0 1.8 1.0 1.9 0.9 1.4 1.6 1.5 3.0 1.1 1.0 4.4 2.9 1.2 0.9 2.6 0.9 14.0 16.5 27.0 22.4 16.7 24.4 18.2 16.3 20.0 15.3 16.4 23.1 25.9 16.0 22.6 43.8 34.2 77.4 41.3 17.6 34.7 42.2 41.6 22.7 95.0 44.3 20.0 38.6 64.6 31.9 49.1 111.2 33.2 24.6 446.2 31.3 34.6 31.5 60.9 93.5 77.8 24.4 24.0 36.6 25.5 38.8 26.6 20.7 22.9 73.3 28.2 58.9 71.6 60.2 22.4 33.5 51.0 565.6 42.3 58.6 60.5 25.3 26.8 40.1 45.3 66.4 53.4 34.6 87.8 52.3 45.4 86.5 128.5 90.0 17.8 66.8 39.5 36.2 35.9 69.8 25.3 32.9 82.3 73.5 40.8 19.4 42.1 69.6 PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872421-48876058 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 575.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 340.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.6;granulocytes: 340.1" "Cell line enhanced" "Detected in all" "HHSteC: 282.8;hTERT-HME1: 493.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "CAB018395: AB_2237473, HPA020240: AB_1849404" "unprognostic (2.43e-3)" "unprognostic (3.21e-1)" "unprognostic (7.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.22e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (6.43e-3)" "unprognostic (1.49e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" 199.1 84.7 33.3 49.5 37.4 575.6 97.7 45.9 54.1 99.5 66.9 78.9 36.0 70.1 11.3 98.3 147.4 82.0 185.6 34.8 36.2 95.0 85.1 226.7 33.1 44.8 32.7 101.2 33.4 23.1 65.0 74.8 42.9 60.5 45.5 10.9 41.6 38.6 88.5 191.5 58.8 101.8 29.4 69.0 90.7 23.3 38.7 52.0 69.4 60.6 20.2 110.6 108.4 46.9 55.8 23.7 24.9 20.5 71.2 40.4 39.3 95.1 148.0 106.5 95.9 36.5 27.6 19.1 25.0 69.0 145.5 39.4 9.3 49.7 79.8 10.7 14.4 86.4 14.4 18.1 282.8 20.2 119.2 55.1 135.5 147.0 493.7 48.0 56.3 21.5 118.2 155.6 69.5 6.1 11.1 27.9 6.2 100.3 42.3 12.6 23.1 6.5 22.3 63.8 14.2 24.3 49.2 33.2 230.2 26.0 11.9 36.1 60.6 126.3 31.8 89.3 58.5 82.8 72.1 17.9 46.2 13.7 154.8 161.8 49.4 91.3 22.5 31.1 19.6 36.7 22.2 18.7 35.9 29.7 12.3 11.0 340.1 13.8 37.6 114.6 31.5 36.9 33.3 37.4 45.9 54.1 34.8 36.2 44.8 32.7 42.9 29.4 38.7 46.9 499.1 288.4 225.1 2.3 387.2 482.2 989.5 232.0 730.1 25.0 294.3 220.7 173.3 127.2 204.3 12.9 35.5 104.8 290.3 435.6 3.9 224.0 4.6 619.6 427.4 370.4 170.9 213.5 4.1 94.5 219.0 466.3 430.7 1063.2 708.1 53.3 150.0 14.4 195.0 35.3 4.1 354.1 140.4 146.7 904.4 5.1 58.7 615.3 396.6 9.4 105.1 50.5 20.6 1.0 2.0 233.4 421.8 23.0 477.1 731.5 348.7 9.0 246.2 27.7 85.5 483.5 612.1 7.0 9.5 573.1 431.0 288.4 427.9 102.8 321.8 733.9 PPP4R2 ENSG00000163605 "Protein phosphatase 4 regulatory subunit 2" Q9NY27 3 72996803-73069198 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034695, HPA039837, HPA073758" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA034695: AB_10671231, HPA039837: AB_2676707, HPA073758: AB_2686632" "unprognostic (4.60e-2)" "unprognostic (2.75e-1)" "unprognostic (3.98e-3)" "unprognostic (5.62e-2)" "unprognostic (8.86e-2)" "unprognostic (4.64e-2)" "unprognostic (2.38e-1)" "unprognostic (1.95e-1)" "unprognostic (1.11e-1)" "unprognostic (2.13e-3)" "unprognostic (1.87e-2)" "unprognostic (2.86e-3)" "unprognostic (1.67e-2)" "unprognostic (4.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.23e-1)" "unprognostic (3.35e-1)" 27.2 23.2 16.9 26.8 22.9 101.2 22.7 22.6 25.3 27.9 21.7 26.9 24.7 24.7 19.0 23.0 27.7 23.3 25.8 17.3 17.7 23.6 53.6 18.0 26.3 19.7 19.1 22.9 23.0 25.4 11.0 28.6 21.5 18.3 23.8 24.4 20.7 15.7 25.8 16.7 22.3 18.8 18.9 21.6 21.4 27.1 20.1 36.2 24.8 24.8 25.8 24.0 15.3 38.7 33.6 38.5 80.9 48.2 41.7 35.9 48.8 66.2 46.7 59.0 61.3 56.1 39.8 63.3 37.3 39.7 56.0 23.6 63.6 36.8 76.0 96.6 23.8 71.1 43.6 67.8 45.8 105.7 70.6 40.9 53.6 71.3 58.3 40.9 41.4 62.9 63.6 70.6 49.5 49.3 88.3 45.8 74.8 50.0 31.8 82.0 45.9 58.9 50.0 89.4 18.1 47.7 77.3 49.9 62.1 57.9 45.9 58.7 47.0 52.4 62.4 61.3 57.3 43.1 97.4 125.5 36.9 79.9 60.4 7.9 5.9 14.8 12.5 3.4 13.8 6.9 12.9 13.1 5.1 7.8 11.1 10.0 21.3 11.3 5.7 18.0 17.6 4.3 16.9 22.9 22.6 25.3 17.3 17.7 19.7 19.1 21.5 18.9 20.1 38.7 56.8 57.7 32.4 19.2 58.5 117.1 110.1 115.8 69.4 50.1 53.2 55.5 54.7 47.1 74.0 27.6 14.6 74.8 62.8 72.4 19.6 63.4 58.1 86.3 76.0 61.9 53.8 61.0 45.6 53.1 72.0 61.6 38.2 142.7 30.9 49.1 40.4 76.4 43.1 50.5 34.8 55.5 77.3 39.2 78.1 12.7 53.4 61.6 56.9 41.2 52.6 53.9 54.6 42.3 101.8 71.4 58.3 48.5 69.7 115.7 44.3 45.8 64.0 39.0 39.5 73.9 60.4 100.6 77.1 54.6 109.1 138.3 69.4 59.1 54.5 128.1 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRDM2 "HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2" ENSG00000116731 "PR/SET domain 2" Q13029 1 13700198-13825079 "Enzymes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005809 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA005809: AB_1079673" "unprognostic (2.22e-1)" "unprognostic (3.28e-1)" "unprognostic (5.34e-2)" "unprognostic (1.28e-2)" "unprognostic (6.70e-2)" "unprognostic (2.72e-3)" "unprognostic (1.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.20e-2)" "unprognostic (2.53e-2)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (9.63e-3)" "unprognostic (3.81e-1)" "unprognostic (2.45e-1)" "unprognostic (1.85e-1)" "unprognostic (5.85e-3)" 21.7 15.2 19.4 19.3 21.2 79.4 21.9 27.5 38.7 27.8 7.6 27.1 13.0 24.2 16.4 21.9 20.9 17.0 19.9 21.5 18.2 14.2 13.1 21.4 27.3 18.5 16.6 34.3 14.9 14.7 16.3 16.7 18.7 24.3 13.8 18.1 21.2 17.6 43.8 27.2 23.6 15.0 12.9 20.2 19.2 18.7 16.9 22.6 24.3 30.0 25.0 27.0 26.8 34.7 15.3 8.5 30.3 11.8 23.5 18.0 14.6 19.5 11.8 13.0 14.5 13.5 16.9 46.4 16.7 18.9 11.0 18.5 22.8 11.4 14.4 28.9 16.3 31.2 10.6 6.4 12.9 10.5 25.8 19.1 19.7 13.8 11.4 12.4 13.0 18.0 28.2 52.0 16.5 7.7 16.9 16.6 9.0 12.1 11.4 23.3 16.4 13.9 7.4 17.0 26.3 17.0 15.7 9.8 21.4 18.0 13.9 16.8 23.2 16.7 18.1 15.3 10.9 75.8 55.4 65.5 14.8 24.1 21.9 4.7 4.9 7.5 5.5 3.2 3.5 18.5 4.4 5.2 3.0 13.4 4.9 4.4 9.9 6.2 6.0 5.6 4.4 2.8 19.4 21.2 27.5 38.7 21.5 18.2 18.5 16.6 18.7 12.9 16.9 34.7 41.3 38.5 39.7 34.3 182.9 62.1 54.8 17.1 61.5 49.5 43.8 33.8 41.3 27.1 33.0 23.9 45.9 25.6 77.7 26.9 17.6 17.3 21.7 84.5 62.5 35.1 37.8 21.7 114.5 13.8 16.2 47.6 25.5 121.2 40.5 50.0 26.0 18.8 16.6 70.7 97.0 24.1 14.2 45.6 39.9 15.6 44.1 42.1 30.2 75.9 41.5 21.2 59.8 70.4 122.5 15.5 25.7 45.1 71.7 54.5 34.2 9.0 43.8 39.7 26.3 86.3 34.4 52.7 49.4 65.4 52.1 18.3 74.4 25.8 19.6 64.5 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB034225: AB_1564157, HPA055687: AB_2682886" "unprognostic (6.75e-3)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (7.06e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-3)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (9.31e-3)" "unprognostic (2.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" 9.0 7.7 4.7 11.1 5.1 25.5 9.1 7.0 6.2 7.6 4.4 12.8 10.6 9.0 9.0 11.6 7.2 6.0 8.9 4.8 4.3 9.0 9.5 12.2 13.4 6.7 5.2 6.9 15.5 5.7 7.7 21.0 5.9 10.6 13.7 9.9 13.6 6.2 10.1 15.8 12.4 7.8 5.1 12.8 10.9 12.7 5.0 14.0 10.0 7.2 14.6 8.5 9.4 6.9 16.0 12.2 37.3 25.9 12.5 10.0 59.1 14.8 13.0 14.6 15.5 39.0 24.3 37.1 11.7 14.5 19.7 26.9 40.5 26.6 23.8 56.6 33.1 54.7 13.4 27.1 28.5 57.7 32.4 13.3 31.4 23.2 52.3 9.0 24.2 41.9 27.6 21.8 15.7 27.8 35.2 30.6 55.8 31.4 13.0 36.6 39.6 23.3 14.6 24.6 21.0 24.2 10.4 26.8 21.7 28.9 28.8 32.9 22.2 8.4 13.5 16.7 18.9 20.2 22.6 39.7 13.6 31.5 16.8 4.6 1.9 0.4 2.8 1.6 3.1 2.0 2.8 3.0 2.2 1.4 2.4 2.6 0.5 4.2 2.5 2.5 1.7 2.7 4.7 5.1 7.0 6.2 4.8 4.3 6.7 5.2 5.9 5.1 5.0 6.9 9.5 3.2 15.3 13.7 11.7 7.0 5.2 4.6 8.0 11.7 8.4 7.6 6.2 5.7 5.6 0.0 8.4 19.3 19.4 12.7 1.9 7.3 16.8 9.0 9.4 10.0 11.4 6.3 16.8 13.5 18.5 6.4 11.2 12.1 12.0 12.5 8.6 6.0 10.4 16.8 12.7 16.3 0.0 16.3 8.0 5.6 6.5 9.9 5.4 12.2 9.9 4.5 13.4 14.1 27.3 15.0 19.2 4.9 16.9 11.2 6.5 3.6 6.0 9.5 0.0 7.8 7.2 14.0 11.6 10.5 7.2 26.8 11.5 5.2 14.8 8.1 PRPF40A "FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40" ENSG00000196504 "Pre-mRNA processing factor 40 homolog A" O75400 2 152651593-152717997 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038272, HPA038273" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA038272: AB_2675923, HPA038273: AB_10671526" "unprognostic (1.81e-1)" "unprognostic (2.91e-1)" "unprognostic (4.31e-3)" "unprognostic (4.49e-3)" "unprognostic (1.55e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.62e-2)" "unprognostic (3.61e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (1.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.24e-2)" "unprognostic (2.05e-2)" 16.7 16.7 9.0 24.7 9.8 45.0 21.5 14.3 10.4 16.8 9.4 24.2 23.0 18.6 15.7 27.6 18.0 17.4 15.3 8.7 10.3 18.9 21.7 17.4 30.4 10.4 8.7 18.9 19.7 24.0 10.5 22.2 10.9 18.4 20.9 16.7 16.6 15.0 22.8 21.0 23.0 17.4 9.9 20.7 22.2 25.5 8.7 31.5 24.6 20.0 28.1 27.1 15.1 12.3 63.4 62.9 68.9 70.8 39.1 51.8 95.5 61.8 55.2 86.0 78.9 120.0 57.8 130.9 88.0 62.7 49.2 63.8 90.8 74.3 91.6 72.4 78.6 121.8 55.7 79.9 50.7 135.4 81.6 41.7 61.9 113.8 127.3 52.4 67.5 60.8 133.2 60.6 52.9 38.4 57.2 63.4 102.9 41.2 75.8 110.4 73.3 86.9 43.7 99.8 82.2 56.0 73.9 53.5 67.6 50.6 46.8 85.4 79.1 90.3 56.6 51.9 81.4 38.8 67.7 130.6 57.9 78.2 56.1 87.6 70.1 91.7 66.7 86.5 62.3 65.5 62.1 60.7 79.4 70.3 65.5 58.8 61.1 70.4 101.1 84.8 58.8 80.1 9.0 9.8 14.3 10.4 8.7 10.3 10.4 8.7 10.9 9.9 8.7 12.3 98.5 112.2 118.5 48.3 120.3 141.0 120.0 117.9 101.3 65.0 73.6 70.6 64.4 55.8 122.1 53.3 73.0 123.1 123.7 67.2 49.0 110.0 150.3 101.0 126.6 97.4 78.3 105.6 56.4 111.5 155.9 96.4 74.9 121.0 123.4 111.0 53.9 72.5 109.2 60.6 53.3 81.5 87.5 95.7 114.5 36.4 69.3 125.5 55.2 44.0 184.1 62.7 107.1 44.7 71.3 128.3 86.8 79.7 112.1 131.7 69.5 75.7 152.6 75.2 98.6 104.8 132.1 239.0 121.4 141.6 151.7 132.2 119.9 164.9 103.7 148.4 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favorable (6.82e-5)" 9.1 7.2 4.8 11.3 5.4 27.3 8.1 7.5 6.7 5.8 5.2 8.6 10.2 9.9 10.1 8.4 4.4 6.1 5.0 4.7 5.1 4.2 4.3 6.8 14.2 5.4 5.5 8.4 6.8 4.2 3.3 7.6 5.3 6.3 8.6 15.9 8.4 5.5 16.3 13.3 9.0 5.6 4.9 11.2 8.1 3.8 5.5 8.8 6.5 4.5 10.0 6.7 7.0 6.9 6.0 3.9 14.4 12.1 8.3 7.3 12.3 7.7 3.4 4.7 5.2 6.9 7.1 8.1 5.7 5.1 4.8 12.8 10.1 6.8 7.1 4.4 11.1 6.7 19.1 11.5 3.6 11.2 10.6 5.7 6.9 5.4 6.6 11.0 5.1 6.5 11.6 3.1 7.4 2.7 7.2 26.3 6.0 3.8 4.3 9.9 6.1 11.2 8.4 10.2 7.9 7.3 4.7 3.9 5.5 16.9 9.6 7.9 7.3 11.2 6.5 4.3 8.2 7.5 7.9 6.9 3.2 7.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.4 7.5 6.7 4.7 5.1 5.4 5.5 5.3 4.9 5.5 6.9 122.4 109.0 103.2 35.6 110.5 83.5 64.0 43.1 69.4 88.6 80.4 49.5 79.1 61.5 75.1 97.5 89.6 61.8 151.3 94.9 72.4 64.4 15.6 115.9 143.5 85.8 75.3 79.1 42.8 56.8 49.9 78.7 88.2 113.4 90.5 96.2 61.1 85.8 41.1 106.0 49.8 88.8 50.8 71.6 49.4 20.6 98.8 71.4 35.6 49.6 97.4 81.2 118.4 50.8 68.1 62.8 61.5 89.1 101.9 62.8 55.5 89.5 71.7 184.0 59.2 105.3 85.8 66.1 76.5 66.7 91.4 63.6 106.2 93.1 87.7 65.2 PRRC2C "BAT2D1, BAT2L2, KIAA1096, XTP2" ENSG00000117523 "Proline rich coiled-coil 2C" Q9Y520 1 171485551-171593511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025766, HPA028659" Approved Enhanced Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA025766: AB_1845277, HPA028659: AB_10600786" "unprognostic (4.16e-1)" "unprognostic (2.40e-2)" "unprognostic (6.66e-3)" "unprognostic (8.71e-2)" "unprognostic (6.07e-3)" "unprognostic (1.85e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (2.28e-1)" "unprognostic (8.19e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (7.76e-6)" "unprognostic (7.03e-2)" "unprognostic (2.62e-1)" "unprognostic (1.82e-1)" "unprognostic (4.34e-2)" 30.9 21.0 26.8 33.3 25.8 72.5 32.7 32.1 35.0 34.0 19.0 27.0 21.6 30.2 37.5 36.7 29.7 26.2 22.7 22.9 34.2 28.8 31.1 35.8 44.8 27.5 27.1 34.3 28.9 33.8 25.7 34.2 27.6 28.2 31.9 34.5 30.3 27.1 25.7 39.7 34.0 25.4 20.3 36.0 28.9 29.3 26.4 49.6 27.8 23.7 43.4 38.5 34.4 30.7 84.9 64.3 88.1 58.4 61.0 70.5 65.2 47.8 67.7 54.8 49.7 99.1 59.0 123.9 73.1 70.4 44.3 73.8 96.5 76.1 83.8 70.1 51.4 94.2 51.2 69.5 63.3 154.4 73.8 68.6 57.1 92.7 137.3 49.3 80.9 66.6 126.8 66.6 63.0 40.3 92.8 65.2 116.8 67.5 110.5 69.3 65.5 60.7 77.8 93.3 56.7 58.3 72.6 85.4 56.0 115.8 58.2 107.0 101.6 61.9 57.0 60.7 100.4 55.5 63.4 175.3 39.4 74.7 56.7 2.2 1.3 0.7 1.3 1.2 1.3 1.7 1.2 1.2 0.6 2.0 1.1 1.3 3.4 2.5 1.4 2.0 1.0 0.6 26.8 25.8 32.1 35.0 22.9 34.2 27.5 27.1 27.6 20.3 26.4 30.7 233.8 298.1 224.7 81.0 272.5 167.0 270.8 107.5 198.6 164.6 105.4 104.6 115.7 133.0 198.3 86.5 139.7 204.0 325.0 190.0 25.4 174.0 63.9 228.0 246.7 214.5 165.1 139.0 101.5 151.3 210.1 189.1 157.0 378.3 263.2 132.8 130.3 119.0 128.9 138.0 108.6 162.3 57.0 142.8 183.0 36.5 139.1 211.0 96.0 91.8 227.9 120.4 269.8 87.9 143.2 223.1 145.2 96.3 281.8 294.3 99.6 40.1 132.1 170.4 78.9 218.1 184.2 247.7 160.8 178.0 145.9 476.8 317.3 178.5 168.5 335.5 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PSMG2 "CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1" ENSG00000128789 "Proteasome assembly chaperone 2" Q969U7 18 12658043-12725740 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 537.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 436.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041517, HPA046741" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA041517: AB_2677530, HPA046741: AB_2679780" "unprognostic (2.28e-2)" "unprognostic (9.44e-3)" "unprognostic (9.68e-2)" "unprognostic (1.15e-1)" "unprognostic (4.40e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.09e-4)" "unprognostic (5.91e-2)" "unprognostic (2.27e-1)" "unprognostic (1.73e-1)" "unprognostic (9.04e-2)" "unprognostic (1.23e-1)" "unprognostic (4.82e-2)" "unprognostic (6.75e-3)" 65.6 50.3 43.5 44.8 43.4 91.9 65.2 47.0 54.8 53.0 43.2 56.3 48.3 49.0 67.5 63.5 47.7 53.2 47.3 43.5 44.9 57.2 65.6 44.3 65.1 44.7 42.8 60.6 55.9 31.1 31.8 52.9 44.4 42.5 60.5 25.1 46.6 47.9 50.9 56.0 47.8 53.0 46.9 43.8 53.7 89.7 42.9 67.6 49.6 39.5 63.7 63.8 52.0 49.2 82.6 51.3 58.2 74.0 100.1 142.5 75.0 81.3 115.7 131.1 147.8 89.1 84.6 90.6 64.6 86.2 108.3 49.8 93.7 99.9 112.2 48.6 52.4 50.1 43.0 101.8 100.7 170.7 78.7 116.8 76.0 80.7 107.6 81.3 92.5 78.7 77.4 112.9 102.4 83.0 109.9 226.1 46.2 436.4 67.8 78.8 87.5 130.2 121.0 106.3 69.6 52.5 77.5 88.1 78.1 56.3 75.8 136.2 63.5 148.9 203.3 131.3 89.4 101.1 142.9 111.1 90.1 88.5 63.3 84.9 89.3 87.6 65.3 95.1 77.6 70.3 84.0 74.8 80.5 62.5 74.6 72.2 30.9 73.9 111.6 65.7 108.2 91.7 43.5 43.4 47.0 54.8 43.5 44.9 44.7 42.8 44.4 46.9 42.9 49.2 96.1 51.3 50.1 42.7 76.4 91.0 98.8 145.2 80.8 25.1 81.4 99.2 36.0 82.9 80.9 82.8 22.9 183.0 80.9 70.8 154.6 110.5 537.7 59.8 75.8 83.9 68.6 97.2 50.1 110.8 140.3 99.3 59.1 53.3 60.9 74.9 101.7 53.1 147.6 25.2 50.3 87.8 54.9 133.0 88.7 140.8 134.2 100.2 72.9 26.2 130.7 63.8 50.4 34.7 38.5 103.2 84.2 97.0 67.1 126.1 120.6 193.8 68.7 21.4 85.5 78.4 89.8 344.9 216.8 119.5 90.1 186.3 78.8 122.3 103.6 130.7 PSPC1 "FLJ10955, PSP1" ENSG00000121390 "Paraspeckle component 1" Q8WXF1 13 19674752-19783019 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 173.4;Inhibitory neurons: 164.7;Spermatocytes: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038904 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "HPA038904: AB_10673291" "unprognostic (2.13e-3)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.13e-3)" "unprognostic (9.57e-2)" "unprognostic (1.09e-1)" "unprognostic (1.69e-3)" "unprognostic (3.04e-3)" "unprognostic (2.92e-1)" "unprognostic (3.69e-2)" "unprognostic (8.61e-2)" "prognostic favorable (1.46e-4)" "unprognostic (7.72e-2)" 10.9 13.0 11.5 13.2 11.5 53.7 16.2 12.8 13.9 12.5 9.9 14.9 12.4 14.8 21.7 14.0 16.2 12.1 11.1 11.8 10.6 12.2 8.9 9.9 20.8 12.1 9.0 13.7 9.5 9.5 10.3 13.8 10.6 11.0 15.5 17.4 10.0 8.3 20.9 14.4 12.4 12.6 8.7 11.1 12.0 25.0 10.5 23.1 12.2 12.7 21.9 20.4 10.0 15.8 50.5 20.4 46.6 23.3 18.9 19.8 60.3 26.1 34.0 48.3 43.6 68.4 27.8 67.8 27.7 27.9 25.4 24.6 54.7 32.2 50.0 28.9 27.3 76.4 14.1 83.1 37.4 55.3 46.7 31.6 6.5 29.8 32.9 19.2 41.7 65.9 42.8 26.1 43.2 54.1 65.5 52.8 65.5 27.3 28.0 43.7 46.8 34.6 50.8 74.6 42.7 22.0 35.8 59.1 23.1 44.9 34.5 56.6 25.1 28.9 27.7 28.0 25.4 22.5 14.5 115.1 13.2 32.7 35.2 14.8 21.3 14.5 11.8 22.7 12.0 23.3 15.1 11.0 19.1 22.5 15.4 11.2 16.9 11.9 18.1 20.9 21.8 15.7 11.5 11.5 12.8 13.9 11.8 10.6 12.1 9.0 10.6 8.7 10.5 15.8 21.0 19.2 29.5 79.3 36.4 33.3 24.9 16.4 23.3 43.2 24.6 21.0 28.6 21.5 18.9 16.5 58.4 70.0 41.0 16.4 21.5 31.3 17.4 40.0 33.9 24.0 25.2 23.1 173.4 34.1 104.7 25.1 25.5 39.4 9.5 28.0 23.9 11.1 27.2 30.3 164.7 20.0 12.2 25.7 25.3 21.4 31.4 27.7 19.6 92.8 45.2 25.5 27.8 115.6 156.4 26.8 22.2 26.7 31.8 16.5 16.1 23.8 25.9 69.1 32.9 27.2 27.4 171.5 75.4 24.0 34.1 80.4 38.9 48.1 27.2 26.2 PTAR1 ENSG00000188647 "Protein prenyltransferase alpha subunit repeat containing 1" Q7Z6K3 9 69709522-69760011 "Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021248 Uncertain Approved "Centriolar satellite,Rods & Rings" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Centriolar satellite" "Rods & Rings" "HPA021248: AB_1855872" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-2)" "unprognostic (1.23e-1)" "unprognostic (9.47e-2)" "unprognostic (9.40e-2)" "unprognostic (1.71e-1)" "unprognostic (4.16e-1)" "unprognostic (6.99e-2)" "prognostic favorable (4.65e-4)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" 9.7 6.6 11.8 9.7 9.8 33.8 12.8 9.5 10.9 10.9 11.3 10.6 6.9 11.2 7.4 8.3 9.7 8.0 8.9 10.3 8.6 14.1 13.3 11.3 11.6 12.5 12.0 12.6 11.0 15.4 6.7 9.8 9.2 7.2 12.8 21.4 10.4 5.7 14.4 10.0 10.6 8.4 8.5 11.3 7.6 9.6 16.1 20.1 10.0 11.7 8.9 9.2 10.8 13.5 11.8 11.9 18.7 9.1 16.4 21.2 10.4 27.2 17.5 8.1 8.9 3.8 7.7 12.2 12.5 20.9 8.1 18.0 39.4 10.2 19.3 11.1 10.7 18.8 24.3 10.8 18.0 16.7 16.2 14.1 9.4 14.4 22.7 16.9 14.6 19.9 11.7 24.7 23.3 3.2 14.5 6.5 24.9 12.2 9.9 13.1 29.6 9.2 23.4 10.3 13.7 17.2 16.6 8.0 15.5 17.4 5.5 8.3 27.3 22.3 20.4 18.5 22.3 17.2 18.2 7.4 15.0 16.1 41.6 5.6 2.3 4.2 2.8 3.3 2.6 1.9 2.5 2.2 2.0 1.6 2.8 2.9 7.3 2.9 2.0 1.1 4.3 1.4 11.8 9.8 9.5 10.9 10.3 8.6 12.5 12.0 9.2 8.5 16.1 13.5 26.0 35.3 21.6 104.8 26.3 16.7 19.4 17.7 21.6 29.1 21.1 18.5 19.1 40.0 17.9 33.1 81.3 20.1 28.5 29.2 15.6 13.3 19.2 17.0 24.8 24.5 11.4 23.8 21.7 7.7 14.6 21.6 12.2 16.8 17.7 28.7 20.0 32.6 12.7 33.7 33.0 28.6 36.7 31.1 18.3 22.1 31.1 22.9 32.0 51.5 28.6 31.8 26.8 82.0 62.2 12.5 21.3 23.0 22.1 23.2 14.7 41.4 18.8 56.2 26.3 26.1 21.1 57.0 10.3 19.5 15.3 9.6 26.0 21.6 22.2 25.5 PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.7;pancreas: 54.2" "Cell type enhanced" "Detected in many" "dendritic cells: 134.8;Langerhans cells: 130.7;Macrophages: 90.2;T-cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 43.2;HUVEC TERT2: 28.7;LHCN-M2: 27.6;RT4: 43.1;THP-1: 27.4;TIME: 54.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.48e-4)" 11.7 9.7 0.7 15.1 0.5 85.7 6.3 0.9 1.0 3.1 1.1 20.3 20.6 2.7 1.2 5.6 12.1 11.2 6.4 0.8 0.8 8.5 4.1 18.3 15.4 1.8 2.4 1.2 54.2 1.0 1.1 3.0 1.7 3.0 17.0 0.1 3.5 2.5 3.9 3.8 24.8 5.9 1.7 12.5 19.7 2.9 1.0 19.4 2.8 6.8 9.3 11.6 2.4 3.3 3.7 0.8 0.0 0.1 16.7 19.7 0.1 0.3 1.4 1.0 0.7 0.0 1.1 0.4 0.3 0.0 17.5 2.8 0.2 6.7 1.7 43.2 0.8 0.0 1.5 0.0 15.1 15.2 3.0 2.1 1.0 10.2 4.1 2.3 28.7 14.7 0.0 10.2 27.6 0.0 16.3 7.0 0.1 0.7 6.5 10.7 2.7 1.4 3.9 43.1 0.0 0.0 0.6 1.3 0.1 0.6 6.6 27.4 54.0 5.5 0.0 0.1 1.3 0.1 0.3 2.0 2.4 11.3 1.5 5.3 7.1 14.6 15.8 19.0 9.0 1.8 9.5 9.9 8.1 1.6 5.7 8.1 12.8 3.8 24.7 1.1 8.4 7.3 0.7 0.5 0.9 1.0 0.8 0.8 1.8 2.4 1.7 1.7 1.0 3.3 44.5 12.8 9.0 1.3 46.4 61.2 5.8 16.2 22.8 0.0 9.4 9.1 3.9 0.0 10.2 7.3 0.0 0.2 134.8 45.7 0.0 0.9 3.7 1.6 1.4 18.0 13.1 2.5 2.8 7.7 0.9 30.0 29.6 2.2 10.1 4.6 3.6 0.8 29.5 0.0 3.4 53.8 4.1 49.7 130.7 1.8 0.9 90.2 19.6 3.7 48.8 0.1 57.7 1.5 7.1 2.9 28.1 0.4 38.6 6.7 16.3 0.1 13.0 0.3 0.0 39.1 11.8 7.1 1.0 17.5 30.4 0.3 214.9 0.1 31.4 1.4 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTMA TMSA ENSG00000187514 "Prothymosin alpha" P06454 2 231706895-231713551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA047183 Approved Enhanced Nucleoplasm,Cytosol No No 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" Nucleoplasm Cytosol "HPA047183: AB_2679972" "unprognostic (1.49e-3)" "prognostic favorable (6.56e-4)" "unprognostic (3.73e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (5.99e-2)" "unprognostic (1.56e-2)" "unprognostic (3.72e-3)" "unprognostic (2.35e-3)" "unprognostic (9.24e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (5.54e-2)" "unprognostic (6.07e-2)" "unprognostic (3.81e-3)" "unprognostic (8.64e-3)" 1203.7 522.8 832.1 1028.5 1020.8 2322.6 1026.6 865.2 1035.4 1185.1 644.5 1045.1 703.0 1110.9 698.4 1186.1 1022.9 565.9 541.0 779.9 898.4 1203.7 652.1 933.2 1396.2 952.9 933.7 1078.5 1090.3 481.3 398.6 688.1 919.2 722.6 985.0 437.1 765.6 604.7 305.9 1425.4 935.1 699.4 875.4 896.2 873.2 237.1 929.1 2059.3 1002.8 246.4 1523.2 896.5 999.1 1137.2 2436.8 1416.4 1990.8 1788.7 592.5 783.4 2037.5 1614.2 1346.2 1379.8 1436.6 1380.8 2759.6 3811.5 1795.4 1271.0 948.1 1252.2 2830.6 1992.5 1738.6 3027.0 2228.9 4906.7 1096.2 2266.8 732.6 5621.1 2018.0 1143.7 733.1 1226.2 1002.6 1307.0 2286.8 3049.7 2910.9 1573.5 1222.0 3433.7 7998.5 7671.0 3004.9 2381.4 1180.4 5426.1 1408.4 2601.9 1719.2 2116.3 4041.8 2483.3 1851.0 1833.5 1507.1 1552.9 1383.9 4430.2 1704.1 1154.2 2052.5 1429.4 1769.7 1887.9 999.3 7614.4 790.8 3401.9 1897.3 2067.1 1713.8 1146.7 1346.2 1695.8 1945.2 2776.6 1928.5 1640.8 1828.0 2438.2 2109.4 1808.0 321.7 1782.3 1957.1 1944.4 2506.6 4661.6 832.1 1020.8 865.2 1035.4 779.9 898.4 952.9 933.7 919.2 875.4 929.1 1137.2 3907.5 971.2 1529.2 49.6 4518.0 7745.0 3851.3 5347.3 5459.5 703.1 3534.0 3673.7 259.7 1974.5 2483.8 2273.2 294.0 2599.4 4054.7 1741.3 3785.9 3474.2 103.3 2713.9 3364.3 4186.4 1695.3 3942.3 37.4 4190.1 5153.9 2404.0 2340.5 3092.6 2928.1 2349.3 1940.1 1347.6 3134.5 812.6 40.9 3178.6 3733.2 3492.4 8474.1 201.4 1306.3 3470.5 3689.1 78.7 3334.5 2195.9 2988.7 40.7 282.0 3669.3 2492.8 1404.5 3523.3 4524.2 1624.2 3136.2 1925.7 934.2 1926.2 2766.5 4571.8 1157.6 2467.8 5778.6 7944.4 2734.1 4276.7 1312.4 3381.3 4052.2 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 QRICH1 "AB-DIP, FLJ20259, VERBRAS" ENSG00000198218 "Glutamine rich 1" Q2TAL8 3 49029707-49094363 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Unfolded protein response" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037677, HPA037678" Approved Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037677: AB_10671883, HPA037678: AB_2675603" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.29e-2)" "unprognostic (1.67e-1)" "unprognostic (2.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.77e-3)" "unprognostic (6.94e-2)" "unprognostic (2.82e-2)" "prognostic favorable (7.46e-4)" "unprognostic (1.12e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-3)" "unprognostic (5.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.76e-1)" "unprognostic (1.06e-1)" 29.8 27.9 15.4 30.5 17.0 61.0 27.8 25.3 20.2 25.8 16.0 25.9 26.3 28.6 25.9 30.0 27.6 25.2 26.0 16.9 14.8 21.3 23.5 27.8 40.1 14.7 13.2 34.0 26.0 33.2 24.8 27.0 14.6 25.8 25.2 30.4 28.3 26.3 34.8 35.4 31.0 28.9 13.2 35.8 25.9 44.5 13.3 51.9 25.7 32.4 41.9 26.8 23.7 16.9 41.4 39.6 78.6 35.6 48.2 45.8 48.2 48.4 60.3 75.6 70.7 44.3 50.8 65.6 29.1 58.9 62.8 33.5 69.0 63.0 64.8 57.8 45.1 65.5 52.9 37.8 43.1 57.9 75.0 53.3 47.4 74.8 46.6 46.2 60.3 62.7 45.0 58.6 51.6 31.8 84.9 41.4 62.3 43.7 48.9 43.3 40.3 55.4 47.6 63.2 29.9 58.9 54.9 47.7 39.7 59.3 42.4 65.5 52.5 49.0 55.1 43.7 69.8 54.2 66.6 82.2 44.0 55.2 57.2 21.3 15.6 19.1 18.1 18.9 21.5 16.6 17.3 20.6 18.5 16.6 18.3 22.0 11.7 18.1 33.0 13.5 19.8 14.3 15.4 17.0 25.3 20.2 16.9 14.8 14.7 13.2 14.6 13.2 13.3 16.9 21.8 9.6 18.9 19.6 30.5 22.2 13.7 16.0 17.1 13.6 20.6 17.7 21.1 14.3 17.9 20.2 22.9 25.7 28.2 16.6 1.9 15.9 15.8 19.8 20.7 19.6 25.9 22.5 37.9 14.0 27.8 20.3 23.9 27.5 16.5 20.0 18.9 20.4 19.7 11.8 39.1 20.6 10.2 25.3 18.3 10.9 22.4 19.5 12.4 14.0 22.3 12.5 15.5 24.6 25.5 18.6 10.5 30.9 39.7 18.0 14.4 10.1 15.2 17.6 6.6 21.9 25.3 52.4 27.8 24.5 22.6 36.8 28.5 17.0 16.8 15.5 RALY "HNRPCL2, P542" ENSG00000125970 "RALY heterogeneous nuclear ribonucleoprotein" Q9UKM9 20 33993646-34108308 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040971, HPA043614" Enhanced Enhanced Nucleoplasm,Vesicles NA NA 9400 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA040971: AB_2677230, HPA043614: AB_2678581" "unprognostic (2.06e-1)" "unprognostic (9.54e-3)" "unprognostic (3.72e-2)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.06e-1)" "unprognostic (1.27e-1)" "unprognostic (3.66e-1)" "unprognostic (4.20e-2)" "unprognostic (8.59e-2)" "unprognostic (3.29e-2)" "unprognostic (2.88e-2)" "unprognostic (8.61e-3)" "unprognostic (1.64e-2)" "unprognostic (8.80e-2)" 109.7 65.4 72.1 90.4 83.2 189.2 98.2 82.6 79.3 108.9 81.8 127.2 109.8 96.9 41.6 119.6 84.8 70.7 143.2 67.6 77.4 104.4 68.3 117.4 116.9 87.8 81.9 101.2 78.2 62.1 55.6 77.6 84.2 88.3 87.6 55.0 105.3 64.3 178.4 114.6 117.7 70.1 83.7 109.6 101.9 116.5 80.9 161.7 125.5 106.0 99.9 99.3 98.4 100.7 250.4 138.1 247.6 193.9 115.3 110.3 210.1 172.9 136.0 215.1 183.0 375.8 204.0 204.3 238.7 140.6 290.9 259.4 135.8 252.7 119.2 132.2 119.3 468.3 81.4 375.4 147.8 236.2 215.0 122.4 141.6 161.9 175.4 160.7 203.0 245.6 201.7 300.9 135.8 185.9 589.3 266.6 137.5 306.0 277.2 344.4 360.6 250.7 126.7 135.4 235.8 266.6 271.8 248.4 376.6 125.8 256.2 234.4 167.5 414.4 270.7 212.3 206.6 310.7 308.3 353.5 213.0 169.9 201.3 139.3 110.7 221.3 138.8 137.1 100.2 96.5 122.2 150.4 135.3 99.6 107.8 104.0 173.3 186.1 195.5 110.0 141.4 165.3 72.1 83.2 82.6 79.3 67.6 77.4 87.8 81.9 84.2 83.7 80.9 100.7 91.8 54.5 61.3 23.2 98.3 79.2 126.9 102.3 74.6 24.2 74.9 67.8 63.4 58.6 61.7 55.2 18.8 161.3 118.3 287.4 127.2 149.1 48.1 36.4 48.5 92.1 93.0 87.9 19.3 160.5 227.7 78.2 70.8 66.9 59.7 69.7 76.8 39.8 159.6 8.4 14.6 143.2 95.6 112.2 118.1 46.7 65.6 96.9 115.6 50.6 151.3 62.6 163.7 15.6 57.1 190.3 270.7 62.1 206.4 157.5 220.7 107.3 38.8 36.3 111.7 47.7 97.7 106.6 121.1 103.7 80.7 171.4 117.2 51.6 178.6 176.2 RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.7;pancreas: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 132.8;Inhibitory neurons: 67.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 12 "amygdala: 10.6;basal ganglia: 13.6;cerebral cortex: 11.0;hippocampal formation: 17.9;white matter: 11.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022148, HPA022896" Approved Supported "Nuclear membrane,Cytosol" NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Cytosol" "HPA022148: AB_1849474, HPA022896: AB_1849476" "unprognostic (1.85e-3)" "unprognostic (1.02e-2)" "unprognostic (8.92e-2)" "unprognostic (5.39e-1)" "unprognostic (4.04e-2)" "unprognostic (3.92e-1)" "unprognostic (6.52e-5)" "unprognostic (1.18e-2)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.66e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.36e-6)" "unprognostic (3.44e-2)" "unprognostic (6.38e-2)" "unprognostic (9.33e-2)" "unprognostic (7.50e-2)" 1.8 6.4 10.6 4.1 13.6 27.7 4.4 0.9 11.0 3.9 0.0 7.9 8.7 4.1 1.1 3.1 8.1 4.0 14.5 17.9 1.1 5.2 0.6 3.5 2.9 0.0 0.0 4.6 37.3 4.2 5.1 4.9 0.0 3.8 8.1 7.2 10.9 4.7 0.8 3.3 8.2 3.3 0.0 3.9 22.4 3.2 0.0 2.8 2.5 2.0 2.5 2.0 2.5 11.9 8.1 9.9 1.9 8.1 0.0 0.0 15.9 10.7 5.0 1.3 1.2 21.9 3.5 3.0 2.9 1.4 13.5 11.0 6.4 20.0 0.4 0.0 6.9 3.7 14.1 9.9 1.9 0.8 3.9 0.5 17.0 5.5 13.9 7.2 0.2 3.7 21.4 1.4 0.0 9.1 3.1 2.0 11.7 3.9 9.5 13.4 6.9 7.8 5.9 4.1 21.6 52.3 15.5 15.8 6.9 7.4 7.8 2.3 2.4 9.1 14.3 1.6 9.1 0.0 0.0 1.2 0.5 6.9 15.1 0.9 1.4 2.1 2.8 2.7 1.1 0.2 0.9 2.1 1.0 0.2 0.1 1.0 4.2 1.9 3.9 1.7 1.0 1.4 10.6 13.6 0.9 11.0 17.9 1.1 0.0 0.0 0.0 0.0 0.0 11.9 1.5 6.4 2.5 13.7 5.6 2.0 6.6 1.8 1.2 23.6 9.9 7.6 20.2 11.5 2.8 12.9 33.3 7.5 27.2 15.2 9.8 6.0 6.1 9.2 6.8 1.6 48.1 0.8 132.8 12.0 6.0 2.2 18.8 9.2 6.3 3.0 3.6 0.8 3.4 37.0 67.9 21.7 8.2 11.1 4.3 8.3 1.8 11.0 3.6 47.8 12.0 2.1 35.0 8.0 4.2 12.4 24.1 1.5 6.4 16.5 5.7 0.8 4.2 4.6 0.0 7.9 2.5 0.4 3.4 2.8 0.4 3.4 8.2 1.5 14.0 11.3 RAP2B ENSG00000181467 "RAP2B, member of RAS oncogene family" P61225 3 153162226-153170627 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 236.8;Squamous epithelial cells: 259.0;Urothelial cells: 269.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (2.44e-2)" "unprognostic (2.19e-1)" "unprognostic (2.13e-1)" "unprognostic (3.51e-2)" "unprognostic (3.04e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (2.00e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (5.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.32e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-2)" 5.2 2.5 4.9 6.0 7.2 15.6 3.4 1.4 7.4 6.0 2.1 3.8 2.6 3.4 2.9 14.9 2.7 6.3 2.1 12.1 5.2 2.7 4.4 5.0 6.3 2.5 4.8 3.6 2.4 2.3 1.2 8.6 2.1 2.4 3.5 0.9 4.8 2.3 1.3 5.0 3.6 3.1 2.9 7.5 8.7 1.4 8.2 4.7 2.1 1.6 5.0 8.2 7.0 5.4 29.0 10.4 5.0 7.4 10.7 9.7 13.7 7.3 10.8 4.9 5.4 5.5 16.6 2.0 8.0 6.8 8.1 28.5 3.9 13.3 5.7 11.7 7.5 11.7 5.6 10.2 5.6 10.9 17.8 10.5 11.1 7.3 13.6 8.6 11.9 5.5 6.8 23.9 9.3 11.5 10.3 15.7 10.4 6.0 16.1 8.9 13.7 26.3 7.7 27.8 0.1 2.7 7.6 6.9 23.5 8.9 5.1 5.6 23.9 7.5 11.6 8.1 18.5 15.3 2.7 5.2 10.0 12.0 7.9 28.0 17.9 7.5 19.5 27.8 14.7 6.4 16.6 17.2 13.1 3.8 9.3 14.7 7.2 14.1 27.6 9.5 12.7 13.8 4.9 7.2 1.4 7.4 12.1 5.2 2.5 4.8 2.1 2.9 8.2 5.4 39.7 12.8 16.5 1.6 26.0 193.0 145.8 61.1 236.8 3.7 41.3 22.4 4.8 30.0 39.4 16.5 2.1 17.3 94.4 135.3 3.9 31.3 0.6 107.8 40.4 21.5 48.6 40.8 8.9 21.7 49.4 30.7 120.8 173.4 26.6 51.3 25.4 14.7 132.1 3.3 3.0 53.5 40.7 170.6 159.9 1.5 19.3 117.0 35.6 4.7 120.1 7.9 110.2 4.5 1.9 60.6 121.3 14.7 27.8 102.1 31.1 12.3 22.1 5.9 0.0 11.1 18.0 3.8 6.1 259.0 195.2 15.2 52.6 12.3 33.6 269.2 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA replication, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 143.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: AB_2677639, HPA043544: AB_2678543" "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 27.1 25.0 22.9 21.1 23.8 143.6 25.9 33.1 29.9 27.8 21.7 31.5 15.0 33.6 26.3 23.2 32.4 25.5 23.9 22.8 23.5 24.3 26.8 27.9 29.7 24.2 22.8 38.8 22.2 21.8 28.1 31.7 24.4 26.0 20.4 51.1 21.4 19.9 29.7 34.6 26.0 24.1 23.9 29.4 25.6 45.5 24.4 26.6 27.2 25.7 23.5 25.3 24.7 27.7 35.4 18.4 42.5 44.4 31.9 32.9 45.9 28.1 26.1 25.1 27.3 20.5 28.3 49.6 20.3 24.4 28.7 33.3 46.2 24.8 41.9 26.9 35.7 41.9 57.1 58.6 24.7 57.5 23.7 28.8 33.7 33.2 38.9 28.6 36.9 42.2 54.5 43.8 29.7 36.5 45.5 51.2 48.7 24.0 17.3 62.8 42.5 43.3 24.7 31.7 33.4 28.5 39.7 35.1 52.3 47.0 27.4 49.7 32.3 31.0 22.8 27.0 30.8 37.7 40.9 60.9 25.1 36.5 26.1 7.1 1.2 2.0 2.0 2.0 2.2 2.0 2.1 1.5 0.9 1.7 1.8 2.0 2.5 3.5 1.1 3.7 1.7 0.6 22.9 23.8 33.1 29.9 22.8 23.5 24.2 22.8 24.4 23.9 24.4 27.7 139.1 86.6 115.3 47.3 125.7 100.7 103.5 40.8 223.1 67.1 145.6 160.8 147.0 44.3 56.5 27.6 100.1 46.3 88.9 71.5 25.4 48.8 307.5 109.8 123.7 93.7 82.0 83.1 52.5 47.6 57.6 127.1 121.8 203.1 51.3 127.8 64.2 59.5 38.4 62.2 53.4 76.0 28.5 53.5 70.2 41.9 72.4 101.5 62.2 54.4 54.0 53.1 52.5 61.3 58.7 56.4 32.8 58.6 173.7 99.9 54.5 23.9 52.0 61.4 52.6 247.0 112.9 100.3 45.8 161.0 101.7 101.5 110.2 105.3 69.3 111.9 RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB015201: , HPA019824: AB_1856113, HPA049642: AB_2680839" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (4.91e-2)" "unprognostic (9.67e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.37e-4)" "prognostic favorable (7.97e-4)" "unprognostic (2.88e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" 4.7 4.0 3.3 7.0 4.0 44.7 4.2 10.9 4.1 3.2 4.5 4.3 5.3 3.4 3.4 3.2 3.8 4.2 4.6 4.5 2.5 3.2 7.2 4.2 11.3 3.1 3.0 5.9 4.3 3.7 1.6 5.0 3.3 3.6 3.8 4.9 4.6 2.6 7.0 2.9 4.8 3.6 2.7 7.2 5.4 8.6 3.4 8.6 4.6 6.6 9.6 4.5 2.2 5.6 11.8 12.7 11.2 11.6 7.0 7.2 17.6 6.2 8.1 9.5 12.4 15.7 10.6 22.4 9.7 7.0 7.8 16.4 17.6 15.5 13.9 23.4 16.3 18.1 21.0 11.4 9.6 19.9 18.4 6.6 10.5 13.2 12.3 5.0 10.2 16.6 26.1 38.0 9.6 12.1 18.0 15.4 24.0 10.4 7.1 21.1 17.0 15.3 7.8 11.8 13.4 6.8 13.5 16.7 13.1 11.9 11.6 23.5 7.2 9.1 16.2 9.9 11.4 28.8 15.9 48.0 13.6 19.7 11.4 6.3 3.9 5.6 3.7 3.4 5.3 6.1 4.2 3.3 2.8 5.1 3.5 4.3 5.4 3.1 3.9 2.7 4.5 3.3 3.3 4.0 10.9 4.1 4.5 2.5 3.1 3.0 3.3 2.7 3.4 5.6 9.1 6.4 3.7 21.5 18.3 33.1 9.3 7.3 6.2 5.7 10.8 5.0 12.3 5.7 4.8 3.7 14.6 8.7 12.8 9.1 0.0 4.1 9.6 15.9 14.5 8.4 9.6 10.7 30.0 3.5 7.9 8.1 10.2 18.8 28.6 10.6 11.0 18.5 6.5 0.0 26.2 8.4 0.0 6.8 11.4 6.7 4.1 7.7 8.8 39.4 6.1 3.9 7.2 29.1 31.2 4.3 3.9 5.3 15.5 9.6 8.8 4.5 10.6 7.3 0.0 11.2 12.4 30.6 13.9 9.4 33.8 4.7 14.3 6.5 9.9 8.6 RBM22 "Cwc2, FLJ10290, fSAP47, ZC3H16" ENSG00000086589 "RNA binding motif protein 22" Q9NW64 5 150690792-150701077 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001634 Supported Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA001634: AB_1079746" "unprognostic (1.94e-1)" "unprognostic (1.17e-3)" "unprognostic (6.86e-3)" "unprognostic (1.00e-2)" "unprognostic (1.49e-1)" "unprognostic (3.04e-2)" "prognostic unfavorable (5.50e-6)" "unprognostic (7.08e-2)" "unprognostic (2.51e-1)" "unprognostic (4.58e-2)" "unprognostic (8.71e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (7.29e-2)" "unprognostic (2.37e-1)" "unprognostic (7.82e-2)" "unprognostic (9.87e-3)" 20.3 15.8 18.8 19.3 21.1 64.5 22.2 21.8 28.5 21.3 17.4 22.5 19.7 23.5 19.8 16.8 25.4 22.7 20.9 18.9 19.7 21.8 21.3 22.7 29.2 21.0 18.9 30.7 18.1 23.9 10.9 22.6 20.6 17.7 23.4 23.6 16.4 19.6 27.3 18.8 19.0 21.3 20.3 26.7 19.1 11.6 19.6 41.6 22.2 34.3 32.3 26.1 16.0 26.0 34.9 37.3 56.0 66.2 37.2 34.3 79.4 35.0 39.1 68.4 75.7 61.3 50.7 51.7 54.5 33.6 65.1 36.1 73.0 63.3 71.0 57.6 55.6 41.4 35.1 26.3 35.4 74.4 47.0 29.1 50.1 56.5 37.0 30.2 48.9 41.7 44.3 50.7 43.2 41.3 68.4 50.6 33.8 42.2 37.6 69.8 46.4 45.9 34.0 35.6 52.4 39.1 39.3 64.4 65.2 33.4 67.2 64.9 33.0 55.5 43.7 24.3 64.4 46.8 56.0 74.2 44.0 66.3 42.6 27.0 30.6 51.8 33.9 36.7 38.2 37.9 31.4 32.5 36.5 35.9 33.2 31.8 52.8 43.8 46.9 19.7 37.4 33.4 18.8 21.1 21.8 28.5 18.9 19.7 21.0 18.9 20.6 20.3 19.6 26.0 69.4 28.9 28.2 8.5 51.3 26.0 52.9 33.9 42.1 33.3 29.3 25.9 28.2 27.1 35.9 16.5 25.0 54.9 56.6 34.2 25.4 36.3 8.4 48.4 44.1 50.5 25.9 34.9 7.4 34.3 43.6 39.3 24.5 101.6 63.4 37.3 27.8 16.6 44.3 30.3 7.6 33.2 44.7 31.1 30.3 3.6 43.2 45.8 23.2 6.5 48.5 35.9 58.7 7.5 13.7 29.1 37.1 45.5 32.1 25.6 29.4 22.5 23.1 19.0 32.9 40.2 37.6 32.0 28.5 22.8 21.7 72.7 56.9 34.4 33.4 39.4 RBM25 "fSAP94, NET52, RNPC7, S164, Snu71" ENSG00000119707 "RNA binding motif protein 25" P49756 14 73058532-73123899 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003025, HPA070713" Supported Enhanced "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA003025: AB_1079748, HPA070713: AB_2686302" "unprognostic (1.15e-2)" "unprognostic (3.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.28e-1)" "unprognostic (4.85e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.22e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.09e-4)" "prognostic unfavorable (4.26e-4)" "unprognostic (6.98e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (1.73e-1)" 31.4 23.2 14.7 36.0 16.2 72.6 30.7 21.5 20.9 28.7 17.2 28.9 23.4 31.4 22.7 28.9 29.5 21.2 22.2 14.5 19.3 20.8 21.2 30.3 40.0 14.9 13.7 31.1 33.2 22.7 25.3 26.7 16.1 22.5 24.0 41.9 31.4 19.8 41.1 33.3 29.9 23.2 12.5 29.7 27.7 28.5 15.9 36.4 29.3 21.9 33.4 28.1 29.8 20.7 97.8 55.6 86.9 66.6 38.1 44.6 76.5 78.4 54.6 59.5 65.2 74.5 61.2 116.7 40.5 54.0 45.1 72.3 100.9 47.2 101.6 73.8 53.3 98.2 43.2 57.7 24.1 87.5 60.0 32.4 33.3 69.7 56.7 51.1 60.0 42.4 102.7 47.6 65.2 73.3 114.4 51.1 73.8 59.6 60.1 97.4 94.8 57.1 49.0 67.4 58.5 55.8 98.5 64.4 35.0 52.2 92.7 37.9 77.2 87.5 85.5 47.3 79.7 50.2 96.0 141.5 39.1 61.3 61.2 17.4 17.2 16.6 19.9 19.2 18.7 22.3 15.8 16.9 18.2 23.7 16.6 17.6 20.3 27.2 17.5 28.7 19.2 11.7 14.7 16.2 21.5 20.9 14.5 19.3 14.9 13.7 16.1 12.5 15.9 20.7 177.8 230.8 319.9 94.7 226.2 227.4 194.3 109.8 198.6 253.8 136.2 139.2 131.5 77.2 191.8 92.0 268.9 151.8 268.4 137.5 17.6 111.0 71.1 160.4 295.6 170.2 155.2 149.3 115.4 122.6 183.5 185.1 146.8 223.2 247.8 183.3 95.3 98.3 113.1 180.0 99.3 146.3 54.9 110.8 180.8 29.2 157.8 169.9 81.8 71.2 176.9 131.2 155.5 84.9 134.1 132.9 111.0 137.7 233.2 236.5 86.3 32.9 137.0 263.0 72.3 234.2 213.4 213.8 212.9 196.7 236.7 185.4 242.9 161.0 162.5 235.1 RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 130000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB062559: AB_2665621, HPA003624: AB_10602123" "unprognostic (1.07e-2)" "unprognostic (1.14e-3)" "prognostic favorable (3.07e-7)" "unprognostic (1.65e-3)" "unprognostic (2.87e-1)" "unprognostic (4.05e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (9.37e-2)" "unprognostic (1.63e-2)" "unprognostic (2.65e-2)" "unprognostic (2.02e-2)" "unprognostic (6.18e-2)" "unprognostic (1.10e-1)" "unprognostic (5.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.59e-1)" 246.8 129.7 21.7 143.2 23.7 301.8 200.9 23.0 33.2 82.3 27.5 122.4 102.1 118.2 89.4 147.1 101.7 71.9 100.7 22.3 27.9 89.2 71.1 130.5 158.5 27.9 24.0 99.3 167.2 94.2 80.1 104.0 26.5 75.7 146.0 51.4 126.0 81.8 112.3 195.3 102.6 114.9 28.7 128.5 114.2 55.9 23.4 156.9 90.1 38.3 206.1 135.0 101.7 29.3 128.2 168.7 172.5 187.3 42.4 226.3 117.2 156.0 272.3 381.6 273.6 173.7 322.5 241.4 50.0 302.3 75.9 107.1 153.2 209.1 304.1 236.5 206.7 126.2 270.5 164.0 153.0 360.8 248.0 168.1 143.8 129.7 124.3 46.2 320.4 131.7 69.8 194.6 268.6 215.9 304.9 209.3 100.5 33.3 230.1 280.7 181.4 196.5 177.7 201.8 70.1 179.1 152.2 206.9 187.5 83.7 272.2 363.6 440.7 127.0 213.0 425.8 278.2 93.7 114.0 279.1 176.5 208.0 263.0 33.0 187.0 30.7 118.4 211.9 141.7 147.5 120.6 119.7 264.1 101.5 120.6 119.5 28.7 150.9 187.0 185.0 137.5 256.3 21.7 23.7 23.0 33.2 22.3 27.9 27.9 24.0 26.5 28.7 23.4 29.3 336.2 166.7 172.1 18.6 391.7 519.4 182.9 379.4 157.6 58.9 326.1 260.5 76.8 154.4 196.7 53.3 47.9 459.9 392.1 165.8 176.1 482.2 6.0 114.6 193.8 292.9 247.4 287.0 18.4 1442.0 726.9 274.2 164.1 234.3 265.2 144.9 195.9 74.6 433.2 42.1 17.7 360.2 136.3 439.5 783.6 17.1 245.7 339.3 522.9 18.7 571.7 181.8 358.4 15.1 18.0 915.3 235.9 147.4 317.7 119.0 143.3 164.3 84.6 87.0 131.5 378.4 299.4 43.6 200.8 285.2 507.8 489.3 352.5 178.2 368.0 202.6 RBM33 "DKFZp434D1319, DKFZp686F102, MGC20460, PRR8" ENSG00000184863 "RNA binding motif protein 33" Q96EV2 7 155644451-155781485 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019232, HPA021497, HPA021768" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA019232: AB_1856121, HPA021497: AB_2176261, HPA021768: AB_1856123" "unprognostic (1.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (3.04e-2)" "unprognostic (2.06e-1)" "prognostic favorable (9.63e-5)" "unprognostic (3.48e-2)" "unprognostic (2.07e-2)" "unprognostic (6.85e-2)" "unprognostic (3.89e-2)" "unprognostic (8.90e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.98e-1)" "unprognostic (2.42e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.29e-4)" 25.4 19.3 14.4 15.2 14.4 62.2 23.3 39.8 18.9 26.8 6.7 24.8 14.0 22.3 17.1 24.3 20.5 8.8 20.1 11.9 20.3 22.7 32.1 30.1 18.8 16.6 11.6 26.1 30.1 8.1 28.3 10.6 14.7 23.0 12.7 33.7 23.0 9.4 30.9 30.5 31.1 9.5 3.7 30.2 26.9 16.9 16.7 31.5 24.5 10.1 15.6 19.4 28.2 23.8 31.9 37.0 22.7 21.1 12.0 15.6 22.9 19.8 14.0 12.0 17.3 34.2 30.0 35.1 25.9 14.7 32.5 22.5 20.8 16.7 15.9 33.3 29.0 33.5 41.7 22.7 13.2 47.7 32.5 15.3 19.3 19.2 27.3 17.4 21.4 38.8 43.6 28.3 17.2 31.1 49.4 40.8 24.4 21.4 23.3 39.2 25.4 29.4 17.4 34.1 23.0 23.5 33.2 21.7 18.0 17.0 16.6 24.8 24.8 20.2 11.9 36.6 26.6 48.8 40.7 52.4 32.7 30.5 26.4 33.5 10.4 23.1 6.6 10.5 5.4 9.5 6.6 8.2 9.1 7.7 6.1 7.8 37.2 9.1 8.3 9.0 9.3 4.2 14.4 14.4 39.8 18.9 11.9 20.3 16.6 11.6 14.7 3.7 16.7 23.8 36.3 32.1 36.4 68.2 52.3 19.6 20.4 19.7 33.6 57.6 22.2 19.8 30.2 14.3 17.0 3.7 83.4 18.1 60.3 32.4 7.9 20.1 25.6 25.9 43.7 27.6 26.3 37.2 86.8 18.0 17.4 26.0 45.3 43.0 39.2 38.9 17.5 30.0 15.9 132.9 85.5 28.1 16.2 28.3 24.4 42.0 26.1 39.3 12.4 87.1 42.9 23.0 42.2 97.0 115.0 23.5 28.5 17.7 93.1 33.3 37.1 18.2 19.2 91.5 13.1 37.5 31.5 29.5 24.4 26.3 23.4 26.1 53.0 33.9 24.0 36.5 RBM34 KIAA0117 ENSG00000188739 "RNA binding motif protein 34" P42696 1 235131183-235161283 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028606 Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA028606: AB_10601494" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (7.30e-2)" "unprognostic (3.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (6.57e-4)" "unprognostic (2.98e-2)" "unprognostic (5.65e-3)" "unprognostic (2.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.69e-8)" "unprognostic (8.50e-2)" "unprognostic (1.85e-1)" "unprognostic (8.73e-2)" "unprognostic (7.09e-4)" 12.2 10.3 11.7 15.0 12.5 35.5 17.0 12.1 13.7 10.0 12.3 12.4 17.9 11.5 15.6 13.9 10.9 12.2 15.5 11.8 12.6 17.1 14.8 11.9 23.2 13.3 12.5 12.8 13.1 9.2 8.7 13.2 13.1 12.0 14.1 6.3 19.9 7.4 19.7 18.2 15.8 11.6 13.1 12.7 14.3 21.3 12.5 16.3 15.6 12.3 20.6 15.7 9.6 13.5 28.6 20.9 23.8 28.8 17.9 33.3 52.8 29.3 24.6 29.4 30.1 26.9 33.7 49.4 29.9 21.0 22.1 40.5 29.0 28.9 28.2 44.4 47.8 35.7 17.0 20.1 35.1 60.4 34.5 28.0 33.2 26.5 19.6 26.5 26.8 50.5 54.5 23.7 38.7 18.0 49.9 48.3 65.3 43.8 15.8 48.0 23.2 57.3 29.5 22.7 26.2 47.1 39.2 27.0 66.4 17.0 55.2 63.5 21.0 26.2 23.0 36.1 59.9 27.8 47.5 47.4 30.8 38.0 40.8 113.9 36.0 44.1 46.1 42.5 55.6 74.1 53.0 59.8 37.2 54.5 49.0 57.4 18.3 58.2 46.4 59.5 77.5 51.5 11.7 12.5 12.1 13.7 11.8 12.6 13.3 12.5 13.1 13.1 12.5 13.5 4.3 19.2 12.8 12.1 11.9 3.2 10.0 7.3 10.2 2.6 6.3 3.7 3.4 7.2 9.1 3.7 10.4 6.2 19.3 4.1 5.9 6.6 7.2 3.2 5.1 6.9 7.8 3.8 10.6 6.2 4.5 10.3 4.6 6.0 23.4 8.0 6.1 3.6 3.3 0.0 11.5 2.7 8.2 5.4 3.2 7.9 4.1 7.1 3.6 15.9 9.4 4.0 23.7 10.1 11.9 8.6 9.6 5.7 10.2 5.3 5.3 12.8 10.7 5.7 0.0 5.0 4.4 7.1 5.3 8.0 3.8 6.2 16.2 3.3 4.5 7.7 RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 19000 "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: AB_1079749" "unprognostic (1.37e-2)" "unprognostic (4.97e-1)" "unprognostic (2.72e-2)" "unprognostic (9.09e-2)" "unprognostic (3.47e-1)" "unprognostic (4.99e-2)" "unprognostic (3.55e-3)" "unprognostic (4.56e-2)" "unprognostic (7.83e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-2)" "unprognostic (7.65e-3)" "prognostic unfavorable (2.78e-5)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (2.64e-1)" "unprognostic (2.28e-3)" 70.1 55.8 18.4 37.7 17.6 172.0 44.6 33.5 28.0 57.8 22.2 56.0 35.1 54.5 9.2 62.3 61.4 40.8 57.3 16.5 25.0 52.2 47.7 62.2 42.3 24.2 24.0 71.1 41.2 27.3 50.0 40.9 19.4 50.2 16.9 49.5 53.4 22.3 70.3 51.2 46.9 19.2 16.0 56.4 49.7 34.3 16.9 51.1 54.2 33.1 24.1 50.7 62.1 26.5 98.8 87.6 77.0 78.5 48.8 53.8 78.8 131.0 50.6 59.6 60.2 109.3 78.5 137.5 90.6 38.9 67.9 91.2 122.3 67.9 66.5 94.6 96.7 174.6 80.7 101.2 23.4 158.6 99.9 14.4 97.6 68.9 38.4 63.7 57.8 46.4 195.5 117.6 46.3 72.2 194.5 87.9 103.2 87.5 96.8 104.9 136.2 91.7 41.5 56.2 77.9 63.4 91.1 94.7 78.4 109.3 70.6 94.6 91.4 100.8 92.5 90.5 115.8 71.6 164.3 204.0 64.7 123.2 79.2 250.9 120.4 197.5 104.7 111.1 103.6 131.1 91.5 97.6 111.8 140.5 85.7 82.1 427.7 127.2 102.2 160.9 114.7 95.7 18.4 17.6 33.5 28.0 16.5 25.0 24.2 24.0 19.4 16.0 16.9 26.5 302.0 233.9 280.9 144.3 441.7 616.4 521.0 283.0 284.0 258.5 339.1 295.4 189.2 191.6 267.6 200.5 316.9 375.2 624.9 278.1 189.8 203.8 48.1 359.2 496.0 299.7 295.3 214.2 130.1 186.0 389.6 337.9 254.9 540.8 525.8 304.4 215.3 202.1 199.8 220.4 120.9 331.3 215.7 207.7 469.5 41.9 262.5 335.5 270.3 129.3 274.3 208.7 400.6 136.2 160.5 221.3 254.8 214.4 391.0 453.6 271.8 150.6 248.0 386.5 164.3 504.0 410.2 263.5 228.1 215.8 586.9 561.6 490.8 218.2 282.8 532.1 RBM7 ENSG00000076053 "RNA binding motif protein 7" Q9Y580 11 114400030-114414203 "Predicted intracellular proteins" Meiosis RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 196.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013993, HPA048003" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA013993: AB_1856137, HPA048003: AB_2680231" "unprognostic (2.90e-3)" "unprognostic (8.21e-3)" "prognostic favorable (6.14e-4)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-2)" "unprognostic (1.93e-2)" "unprognostic (2.89e-1)" "unprognostic (9.38e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.05e-1)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (8.30e-2)" 18.5 9.1 3.4 6.5 5.3 39.8 15.3 7.6 7.8 12.9 3.6 13.1 6.2 13.9 4.9 13.3 13.9 10.5 9.9 4.0 5.1 12.7 18.0 13.7 6.8 6.3 5.0 16.4 10.0 9.6 7.2 11.3 5.0 10.1 11.2 6.8 12.7 8.7 12.2 10.8 11.3 10.9 5.2 10.1 12.1 11.5 4.0 15.2 10.4 14.6 9.3 12.6 13.2 6.6 13.1 13.4 17.0 11.5 21.9 27.6 11.3 31.1 43.5 34.6 37.8 30.7 28.1 24.2 34.5 28.0 26.0 11.0 19.7 23.6 40.4 15.3 8.4 27.5 14.5 27.3 36.7 18.9 15.3 32.2 25.0 31.2 41.7 32.6 30.1 17.1 19.8 2.9 20.8 6.4 23.0 9.5 13.9 13.1 19.7 14.5 29.5 18.2 26.1 22.2 13.1 12.5 18.8 10.4 8.9 27.5 6.8 5.0 26.6 9.1 17.2 10.2 22.8 10.8 12.4 18.8 7.3 22.7 14.9 53.0 15.3 17.8 11.5 13.7 15.2 11.9 11.6 10.5 15.2 9.7 14.8 11.6 14.0 17.3 16.5 14.0 14.7 10.6 3.4 5.3 7.6 7.8 4.0 5.1 6.3 5.0 5.0 5.2 4.0 6.6 49.4 16.0 25.7 2.0 44.0 67.4 78.4 48.4 41.5 11.5 47.4 31.9 15.1 30.0 34.2 29.5 12.5 51.0 52.4 30.8 66.5 49.8 196.4 37.6 38.8 45.0 47.4 26.1 5.4 35.1 78.0 51.7 26.0 51.3 40.0 20.1 37.9 27.5 29.8 8.4 5.6 30.9 40.7 27.4 55.3 29.5 31.4 30.8 42.7 7.5 32.2 24.5 28.8 8.5 10.2 39.0 37.6 17.0 18.0 71.2 38.1 46.5 27.8 13.0 0.0 49.1 47.6 35.3 16.9 32.8 68.6 92.5 46.6 18.7 38.4 82.6 RBM8A "BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP" ENSG00000265241 "RNA binding motif protein 8A" Q9Y5S9 1 145917714-145927678 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 735.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018403 Supported Supported "Nuclear speckles" NA NA 100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA018403: AB_1858908" "unprognostic (3.81e-1)" "unprognostic (3.99e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-2)" "unprognostic (1.12e-1)" "unprognostic (3.16e-1)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (8.79e-3)" "unprognostic (7.27e-3)" "prognostic unfavorable (1.55e-4)" "unprognostic (3.30e-3)" "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-3)" 86.1 74.9 37.2 105.4 39.1 214.7 82.3 38.7 43.0 69.6 35.6 70.5 70.1 67.7 49.3 163.6 62.2 58.0 73.0 36.8 41.7 81.6 77.5 72.8 126.4 39.7 39.8 72.0 59.9 78.4 65.8 85.3 40.8 66.4 56.4 45.0 79.2 48.2 214.9 92.0 69.2 57.7 42.1 81.6 67.5 71.3 40.0 120.7 68.8 100.1 123.7 112.8 80.4 43.9 377.0 300.7 268.8 215.7 94.6 92.2 330.0 224.3 150.7 315.0 230.1 400.0 277.4 342.0 344.9 155.3 166.5 252.5 289.3 245.3 257.0 305.6 275.7 264.2 229.2 299.8 133.6 446.6 222.6 102.2 180.8 283.0 300.3 137.4 238.1 291.9 405.2 314.7 246.2 1033.8 452.3 352.2 463.7 323.9 518.4 394.4 234.6 341.2 203.2 355.6 274.6 335.7 334.5 169.7 316.5 231.0 318.0 534.3 247.3 252.3 324.0 250.9 626.0 352.2 603.4 502.6 226.4 264.9 223.2 464.6 316.5 513.6 337.2 363.9 322.1 444.3 317.6 346.4 318.0 389.6 296.1 328.3 363.7 389.8 361.3 498.4 386.3 582.7 37.2 39.1 38.7 43.0 36.8 41.7 39.7 39.8 40.8 42.1 40.0 43.9 289.1 70.5 132.4 8.1 251.0 332.9 396.7 475.4 244.2 66.3 168.5 184.7 78.0 98.7 262.8 88.3 54.2 376.2 276.0 125.3 187.9 224.1 243.7 148.0 134.3 206.0 158.9 149.2 10.8 223.2 506.3 174.1 80.5 152.8 244.0 136.8 120.3 124.4 204.3 35.3 9.1 127.6 313.3 100.3 265.2 54.4 102.2 170.7 208.1 9.4 197.7 120.3 165.8 6.0 16.1 245.4 159.8 85.4 174.9 259.6 119.5 204.1 195.1 86.3 98.6 213.7 208.1 212.0 168.9 208.1 318.0 735.5 282.1 139.7 141.7 393.0 RC3H1 "KIAA2025, RNF198, roquin, RP5-1198E17.5" ENSG00000135870 "Ring finger and CCCH-type domains 1" Q5TC82 1 173931084-174022357 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027428, HPA027434, HPA027448" Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "Golgi apparatus, Plasma membrane" "HPA027428: AB_10600324, HPA027434: AB_10601235, HPA027448: AB_10601683" "unprognostic (6.91e-2)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" "unprognostic (2.33e-2)" "unprognostic (7.73e-2)" "unprognostic (1.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (5.25e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-3)" "unprognostic (6.83e-3)" 4.8 3.8 2.6 4.2 4.7 19.6 5.2 16.0 5.1 4.9 11.4 5.2 3.4 4.5 4.0 6.1 4.8 4.0 4.6 3.1 5.8 3.9 5.8 5.9 4.9 3.5 3.5 5.1 4.8 3.9 4.6 4.3 4.0 4.2 4.2 8.0 4.4 3.5 10.6 7.4 5.5 3.7 2.0 6.7 4.6 5.3 4.1 5.0 5.0 10.3 5.6 4.5 5.1 7.2 6.6 9.1 4.9 7.7 9.2 7.1 6.8 4.4 6.3 5.0 4.4 8.4 7.3 9.4 7.7 7.2 3.9 6.2 7.5 6.3 7.0 6.6 1.8 8.1 6.8 7.0 5.6 10.7 9.1 6.8 4.8 7.3 4.9 4.6 7.9 4.5 9.4 5.6 6.2 5.0 6.5 9.6 8.5 6.1 1.0 7.0 8.8 6.9 8.9 12.7 5.9 5.3 8.4 10.7 4.3 8.2 7.2 10.7 11.4 6.5 6.5 5.6 5.8 6.9 7.5 11.8 4.4 4.8 6.7 3.4 1.9 2.7 1.1 1.9 1.2 1.5 1.1 1.3 1.0 1.8 1.5 1.3 6.4 1.4 2.6 0.8 0.9 0.7 2.6 4.7 16.0 5.1 3.1 5.8 3.5 3.5 4.0 2.0 4.1 7.2 39.8 41.7 34.5 32.0 49.4 34.4 17.3 14.1 60.9 35.6 53.6 28.3 25.7 25.8 20.0 23.9 81.3 10.6 70.2 37.4 9.8 25.4 13.3 77.5 45.9 32.0 34.2 30.7 46.8 18.9 8.2 34.9 68.8 82.9 15.8 20.3 34.2 36.3 11.5 38.7 43.5 28.9 16.2 37.2 48.2 8.1 15.8 38.5 30.2 40.3 33.0 22.7 30.9 42.3 68.2 24.8 22.1 10.5 52.2 38.3 25.1 9.8 30.2 47.3 19.7 39.0 31.5 35.8 14.0 66.8 40.9 11.6 41.4 16.1 25.9 38.5 RCOR1 "COREST, KIAA0071, RCOR" ENSG00000089902 "REST corepressor 1" Q9UKL0 14 102592649-102730561 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 117.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001956, HPA049327, HPA054241" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB001956: , HPA049327: AB_2680715, HPA054241: AB_2682426" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (9.96e-3)" "unprognostic (1.72e-2)" "unprognostic (1.87e-2)" "unprognostic (4.98e-2)" "unprognostic (1.46e-2)" "unprognostic (6.05e-3)" "unprognostic (7.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.72e-4)" 11.2 5.8 3.3 11.2 3.1 46.1 9.0 4.6 4.1 14.2 3.3 11.0 12.0 9.5 13.3 33.2 9.5 8.7 6.7 5.0 3.6 6.7 9.4 12.9 11.9 3.4 3.5 9.0 7.9 10.4 5.2 20.8 3.6 8.8 11.1 6.3 10.2 5.8 11.8 16.6 12.6 8.8 3.5 8.6 13.4 13.7 4.3 14.5 6.3 10.6 14.7 10.2 19.1 4.2 21.3 19.5 17.2 19.0 13.5 18.6 36.1 21.5 15.2 19.7 18.7 18.0 25.2 23.8 17.1 18.7 9.9 32.6 26.2 15.4 29.4 10.1 9.6 44.2 17.4 17.6 18.4 44.3 38.2 13.1 23.6 17.4 26.5 21.1 21.8 22.1 35.7 17.5 20.1 34.6 27.8 29.9 8.5 23.2 33.1 70.4 17.4 10.6 24.1 25.9 22.2 13.8 48.1 21.9 13.9 21.5 30.0 34.6 23.8 13.6 10.2 43.8 14.2 12.9 16.6 25.0 16.3 32.0 14.6 3.1 1.4 2.2 0.2 1.5 0.3 0.3 0.3 0.6 1.5 0.3 0.3 0.3 3.7 0.7 1.8 0.6 0.5 0.5 3.3 3.1 4.6 4.1 5.0 3.6 3.4 3.5 3.6 3.5 4.3 4.2 15.8 48.1 40.0 32.3 27.3 57.6 27.7 12.0 30.7 8.4 25.6 20.7 16.7 10.0 19.7 3.7 2.1 31.1 39.1 31.5 5.9 6.7 5.1 55.7 36.1 15.9 21.0 32.2 39.3 7.4 20.4 20.2 32.6 58.3 24.1 18.0 11.0 11.7 15.1 10.1 33.8 16.8 10.2 38.8 65.6 4.9 24.2 43.6 24.9 52.5 33.1 9.5 12.3 22.1 23.5 16.7 15.2 21.1 14.8 25.4 18.2 8.0 16.3 5.4 0.0 18.9 19.6 22.5 18.6 46.9 117.6 43.1 26.2 20.3 22.8 72.3 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 REL "c-Rel, I-Rel" ENSG00000162924 "REL proto-oncogene, NF-kB subunit" Q04864 2 60881521-60931612 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4" "Cell type enhanced" "Detected in all" "Langerhans cells: 2061.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 61.2;U-698: 109.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004404 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "CAB004404: AB_670194" "unprognostic (2.77e-1)" "unprognostic (2.05e-2)" "unprognostic (8.26e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (4.41e-2)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (2.15e-1)" "unprognostic (5.87e-2)" "unprognostic (4.38e-2)" "unprognostic (4.37e-1)" "unprognostic (2.82e-2)" "unprognostic (2.91e-2)" "unprognostic (3.53e-1)" "unprognostic (3.85e-1)" "unprognostic (3.66e-2)" 4.8 4.5 2.2 14.1 1.8 37.4 5.5 8.6 4.2 4.6 0.4 4.6 4.7 5.7 2.7 6.0 3.2 8.2 2.2 2.1 2.9 3.4 7.3 6.7 15.8 3.0 1.7 5.0 5.0 6.2 1.9 5.5 2.3 4.1 4.9 9.8 4.6 2.7 2.4 8.3 5.2 3.5 0.5 11.1 5.8 3.5 2.4 9.2 4.1 2.5 16.3 13.1 3.3 3.4 7.2 3.8 3.4 4.5 2.7 2.6 7.3 2.5 3.2 1.8 2.1 3.2 6.0 61.2 6.4 2.2 4.6 7.7 5.3 3.9 4.0 7.0 5.0 6.3 6.5 3.5 1.5 13.3 7.1 2.3 10.1 4.6 7.0 3.0 4.8 6.6 7.6 4.3 1.7 4.0 9.1 5.6 4.2 5.0 1.8 12.0 8.8 2.7 2.8 24.5 3.3 3.5 6.4 7.9 2.3 5.0 4.6 5.5 5.6 5.0 6.0 3.5 3.8 5.4 2.8 109.7 3.0 10.9 2.7 3.4 4.1 2.6 2.8 4.5 2.0 5.9 1.5 2.2 3.5 7.9 1.0 2.1 5.0 2.9 5.7 3.1 1.9 2.3 2.2 1.8 8.6 4.2 2.1 2.9 3.0 1.7 2.3 0.5 2.4 3.4 67.5 320.5 325.8 8.1 430.2 517.6 123.3 69.4 194.6 82.0 95.3 58.5 5.0 48.6 165.0 51.5 85.5 29.0 469.7 59.0 3.9 31.7 4.2 150.5 79.5 103.5 42.5 37.0 16.3 29.4 58.5 97.3 96.4 300.1 412.1 82.4 30.0 19.1 51.7 58.9 16.7 49.1 46.8 141.5 2061.4 3.4 15.5 463.9 135.2 42.2 451.1 21.3 145.2 8.5 9.2 35.1 46.6 23.7 119.5 99.7 34.3 7.7 153.1 56.2 13.1 65.9 73.9 51.5 38.4 158.0 463.1 77.6 303.7 21.3 50.1 260.6 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm NA NA 6500 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041037: AB_10805834" "unprognostic (9.63e-2)" "prognostic favorable (8.05e-5)" "unprognostic (5.12e-3)" "unprognostic (2.25e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.06e-1)" 5.9 5.8 3.7 10.5 4.4 33.8 10.7 5.9 4.9 8.6 4.2 10.3 9.8 11.1 5.4 9.3 9.5 6.7 5.4 6.0 2.9 8.7 13.0 6.8 16.4 3.3 3.2 15.6 7.6 7.1 4.7 7.3 3.2 7.9 12.6 11.5 5.8 8.0 5.6 12.9 9.1 7.7 3.8 8.0 7.2 8.3 3.7 23.4 10.3 4.7 16.1 6.3 7.1 4.3 52.8 49.3 49.1 28.1 12.2 14.7 58.3 38.4 24.0 66.6 49.9 50.2 21.4 56.4 25.9 18.1 42.0 47.2 66.9 34.0 63.2 42.1 58.1 43.9 40.7 36.5 7.6 70.7 38.1 7.8 12.2 50.0 16.8 30.4 28.6 70.3 62.6 21.6 33.3 50.3 93.2 59.2 40.5 29.8 46.1 68.1 61.2 55.3 30.7 47.7 67.5 30.7 62.2 18.2 24.1 30.4 64.4 30.0 13.7 36.9 42.5 50.4 69.5 36.2 51.7 76.9 36.4 51.7 66.1 16.6 5.0 3.6 8.6 8.4 7.6 10.7 10.3 7.4 7.2 9.1 8.0 6.9 5.6 7.9 4.9 6.0 11.4 6.5 3.7 4.4 5.9 4.9 6.0 2.9 3.3 3.2 3.2 3.8 3.7 4.3 4.0 0.0 3.3 4.6 5.6 8.4 6.9 7.1 4.0 4.2 5.2 4.7 3.1 4.3 4.6 9.2 2.1 21.0 4.7 3.6 9.8 8.9 3.0 6.0 6.3 4.3 4.2 45.7 11.8 6.3 25.2 6.4 4.1 6.5 5.7 14.0 3.3 6.0 9.1 1.7 7.3 6.9 4.1 3.2 3.1 2.7 4.1 4.9 0.0 3.7 3.8 9.5 2.1 2.5 5.5 4.1 4.0 8.2 16.4 2.3 3.2 6.6 11.0 6.0 0.0 5.3 8.4 13.4 9.1 9.5 5.4 8.9 7.9 18.7 10.6 4.2 RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646754-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.9" "Cell type enriched" "Detected in many" 7 "Erythroid cells: 278.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.3;K-562: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 48000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016546: AB_630417" "unprognostic (1.15e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "unprognostic (2.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (9.91e-2)" "unprognostic (8.24e-3)" "unprognostic (4.89e-2)" "unprognostic (5.83e-3)" "unprognostic (6.78e-2)" "unprognostic (9.03e-2)" "unprognostic (9.35e-2)" "unprognostic (1.09e-1)" 1.7 2.3 1.3 1.1 1.7 26.9 2.8 2.1 3.4 2.2 1.8 1.8 1.2 2.0 4.4 2.4 2.0 1.2 3.5 1.4 1.6 2.5 2.5 1.5 3.1 1.8 1.6 2.9 3.6 3.9 2.8 1.6 1.7 3.1 1.4 3.6 4.7 1.4 5.8 7.6 1.4 1.4 1.6 2.4 2.5 12.2 1.7 4.9 3.3 3.5 3.2 2.3 1.9 2.2 3.6 5.5 1.0 3.5 3.4 6.2 0.0 1.9 2.9 3.1 3.1 4.4 3.8 5.8 3.8 1.6 7.3 5.2 3.8 3.0 3.3 8.7 3.3 41.3 5.2 1.6 4.3 3.8 4.2 2.8 5.5 4.0 3.6 2.8 3.1 17.1 78.3 4.5 4.9 2.4 12.4 16.4 4.4 1.6 5.2 6.0 0.7 2.6 1.1 2.1 5.3 3.8 5.4 2.4 0.0 0.3 2.8 2.0 1.6 3.9 3.1 2.9 3.4 3.9 10.1 4.7 3.4 4.5 2.1 0.0 0.7 0.4 3.6 0.9 9.6 3.9 8.7 6.2 1.6 3.3 12.7 7.5 0.0 6.1 0.9 1.9 5.4 2.7 1.3 1.7 2.1 3.4 1.4 1.6 1.8 1.6 1.7 1.6 1.7 2.2 2.0 12.8 3.3 1.6 2.8 3.2 4.5 6.0 3.4 2.1 2.3 3.4 7.8 0.0 5.5 1.8 0.0 3.5 4.2 0.5 1.9 2.4 18.2 2.3 2.4 1.4 0.0 278.7 1.6 1.8 12.1 3.2 2.0 1.8 3.8 2.0 2.9 2.1 3.8 1.7 1.9 1.1 14.2 1.6 0.8 8.5 1.8 1.2 0.0 2.8 2.3 3.8 3.1 0.0 1.7 1.7 0.3 1.2 1.0 2.5 0.9 2.9 5.3 1.9 6.6 2.8 2.7 37.2 14.3 4.5 6.8 2.1 4.6 2.5 1.2 2.5 RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 101.3;Endothelial cells: 51.1;Hofbauer cells: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 95.5;HMC-1: 222.1;NB-4: 74.8;U-937: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" 19.8 5.9 2.4 7.4 2.5 77.9 15.6 2.3 2.8 8.7 10.1 13.7 3.2 10.1 3.5 3.1 7.1 4.6 12.8 3.3 2.2 8.6 3.5 13.3 5.4 2.5 2.4 5.7 3.5 3.9 4.3 10.4 2.2 9.5 1.9 1.5 4.1 2.8 7.9 6.3 9.6 6.1 2.7 10.5 8.6 3.7 2.4 16.7 8.2 3.9 4.8 11.8 5.4 2.1 30.5 8.0 4.0 18.9 13.0 9.4 20.8 48.8 21.4 15.8 7.7 0.5 1.1 0.0 1.2 95.5 7.0 3.0 11.2 1.1 14.5 0.2 6.5 1.3 1.5 2.2 19.0 11.4 222.1 5.2 0.3 5.0 1.9 6.1 16.0 4.8 4.7 0.3 18.1 0.4 0.6 74.8 8.6 0.8 0.3 3.2 8.6 0.0 2.9 0.1 0.3 43.6 19.8 0.0 17.6 14.9 0.4 34.7 3.2 12.4 11.0 7.5 0.1 7.1 7.7 0.0 0.2 64.1 19.5 201.5 6.9 80.7 6.1 5.4 6.2 0.1 6.1 5.2 2.1 0.1 9.7 8.7 35.5 2.2 7.3 9.1 4.3 3.8 2.4 2.5 2.3 2.8 3.3 2.2 2.5 2.4 2.2 2.7 2.4 2.1 101.3 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.1 7.4 0.0 0.0 1.8 1.8 0.0 0.8 16.5 0.0 0.0 1.1 0.0 2.3 1.9 51.1 0.0 0.0 0.0 0.9 1.2 9.2 0.0 6.0 1.3 12.5 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.9 0.0 0.0 5.9 0.0 0.0 0.5 1.5 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.5 10.7 4.2 0.0 0.0 RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621399-74666877 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 47.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA048258: AB_2680332, HPA075649: AB_2686761" "unprognostic (4.79e-2)" "unprognostic (6.45e-3)" "unprognostic (6.35e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-3)" "unprognostic (5.04e-2)" "unprognostic (3.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.03e-3)" "unprognostic (2.53e-3)" "unprognostic (1.73e-3)" "unprognostic (2.84e-1)" "unprognostic (4.31e-1)" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" 5.2 3.9 2.5 9.9 3.5 47.7 7.6 4.0 3.2 6.4 4.4 8.0 6.5 6.2 5.3 9.4 6.8 6.5 2.9 2.3 2.9 6.7 5.8 6.1 15.4 3.3 3.1 7.0 10.2 6.8 3.8 8.0 3.2 4.9 9.3 6.2 5.8 5.1 3.3 12.6 6.1 6.1 2.8 8.1 6.2 25.2 3.4 27.1 6.6 2.7 16.7 7.2 6.8 4.7 46.1 57.5 42.6 31.2 8.8 11.9 47.8 40.5 30.9 63.0 54.5 75.4 46.8 63.6 32.1 31.8 31.6 53.9 70.3 42.1 76.9 20.0 42.1 56.3 46.0 43.0 7.6 57.3 56.3 8.6 13.2 79.6 48.7 16.3 27.3 53.2 86.7 27.7 48.1 72.8 84.0 52.2 84.0 26.8 27.7 128.7 28.8 55.9 22.7 47.8 31.5 33.6 65.2 22.8 28.8 38.2 41.7 48.4 26.7 46.0 43.9 26.2 51.4 37.4 75.1 188.3 32.8 43.5 57.0 12.1 4.4 6.5 5.5 4.1 6.1 4.9 4.5 5.1 4.6 5.4 6.7 4.8 4.9 6.2 7.7 3.5 7.2 4.4 2.5 3.5 4.0 3.2 2.3 2.9 3.3 3.1 3.2 2.8 3.4 4.7 6.0 0.0 5.9 4.2 13.2 10.8 6.8 4.0 10.2 6.6 8.4 8.3 3.9 2.8 5.4 1.8 10.4 12.1 15.3 7.6 11.7 6.2 5.4 6.9 5.7 7.2 9.5 22.5 8.9 7.6 8.3 5.9 5.1 6.6 4.5 13.5 11.7 7.4 8.9 3.3 7.1 9.7 2.0 12.2 6.0 6.3 3.7 7.8 16.0 15.0 7.6 3.0 10.3 6.6 15.2 10.0 2.7 4.1 11.6 12.7 4.3 4.6 5.9 6.7 6.6 6.4 5.6 48.5 31.7 9.5 9.2 7.5 10.6 3.6 9.5 11.4 RFX8 FLJ42986 ENSG00000196460 "Regulatory factor X8" Q6ZV50 2 101397359-101475112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Excitatory neurons: 11.5;Inhibitory neurons: 4.5;Late spermatids: 10.2;Spermatocytes: 8.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.6;hTEC/SVTERT24-B: 16.8;LHCN-M2: 6.9;U-87 MG: 9.6;U-937: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA059745 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nuclear bodies" "HPA059745: AB_2684120" "unprognostic (1.02e-1)" "unprognostic (1.88e-2)" "unprognostic (1.24e-1)" "unprognostic (5.55e-2)" "unprognostic (2.56e-3)" "unprognostic (8.14e-2)" "unprognostic (3.63e-2)" "unprognostic (6.04e-2)" "unprognostic (4.93e-2)" "unprognostic (9.55e-2)" "unprognostic (1.51e-2)" "unprognostic (4.76e-2)" "unprognostic (4.73e-5)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" 0.6 0.1 0.0 0.1 0.0 3.7 0.8 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.6 0.0 2.1 1.7 1.3 1.7 0.0 3.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 2.0 0.0 16.8 0.1 0.0 0.0 0.6 0.0 0.0 6.9 0.0 0.7 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.2 0.2 0.0 1.9 3.1 0.0 0.0 0.0 9.6 4.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 16.6 1.4 0.1 1.0 0.0 0.0 11.5 0.0 0.7 2.6 0.0 0.5 0.0 0.1 0.7 0.0 0.1 0.0 4.5 0.0 0.0 0.3 1.6 10.2 0.3 0.4 0.0 2.8 0.0 0.0 0.0 0.5 1.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 1.3 8.5 1.5 0.0 0.0 1.4 0.1 0.0 0.0 0.1 RGS2 G0S8 ENSG00000116741 "Regulator of G protein signaling 2" P41220 1 192809039-192812275 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Translation regulation" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 1871.8;Langerhans cells: 637.8;Macrophages: 621.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 3268.4;neutrophil: 4374.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 4374.2" "Cell line enhanced" "Detected in many" "hTCEpi: 141.8;hTERT-HME1: 96.8;Karpas-707: 94.0;PC-3: 226.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013385 Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA013385: AB_2668827" "prognostic favorable (2.43e-4)" "unprognostic (9.75e-2)" "unprognostic (1.28e-3)" "unprognostic (4.43e-2)" "unprognostic (1.79e-1)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (6.49e-2)" "prognostic unfavorable (2.90e-5)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.16e-1)" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" 129.3 353.8 36.4 241.4 40.7 565.0 126.8 41.8 82.6 67.2 56.7 328.5 142.7 217.4 96.0 256.2 149.2 189.5 73.0 43.6 47.7 53.6 66.3 123.6 37.1 50.3 43.9 137.4 513.3 12.5 198.7 100.1 46.0 182.2 110.1 36.9 27.5 222.4 10.0 37.3 104.9 505.9 41.0 192.1 113.4 18.8 47.5 47.3 22.8 63.7 17.3 259.8 71.7 42.1 0.0 20.1 25.4 2.4 48.9 7.7 1.5 9.9 12.4 3.2 3.4 17.9 11.8 1.7 2.8 9.3 2.5 9.7 16.7 17.5 2.9 2.6 12.3 4.8 12.9 0.4 21.5 12.1 2.8 8.1 141.8 6.5 96.8 18.1 23.9 9.1 4.4 94.0 10.0 0.3 6.6 16.8 34.0 1.9 226.6 6.7 5.9 5.4 16.9 16.3 9.4 47.4 7.1 0.5 11.8 26.0 0.7 6.0 6.7 4.8 4.5 5.2 5.2 55.4 1.7 5.3 67.3 2.4 17.8 3268.4 517.9 754.6 14.3 200.8 32.1 6.4 10.2 10.4 118.8 3.3 5.2 6.6 4374.2 2.3 362.7 16.0 6.7 310.2 36.4 40.7 41.8 82.6 43.6 47.7 50.3 43.9 46.0 41.0 47.5 42.1 22.3 51.3 195.9 6.8 187.2 42.3 47.3 45.0 6.2 18.7 138.5 44.1 69.4 7.2 46.1 136.1 18.8 227.6 145.1 27.0 0.0 33.5 24.6 6.9 51.5 38.6 349.2 3.2 6.6 30.3 24.5 125.8 38.7 7.5 1871.8 2.3 18.5 3.1 374.4 21.9 8.4 96.9 42.7 345.0 637.8 18.3 16.4 621.2 88.9 8.4 305.0 41.5 25.7 3.5 2.4 14.8 60.3 62.8 135.9 36.3 141.5 2.5 20.4 39.0 0.0 61.4 55.5 4.2 16.9 6.1 31.1 124.2 346.1 16.6 32.3 11.3 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389793-7418037 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA017866: AB_2669670, HPA051446: AB_2681488" "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 12.1 9.3 4.1 10.8 4.1 20.6 11.0 5.0 5.3 10.0 3.7 7.9 6.5 10.5 5.2 11.4 8.2 7.5 8.0 4.2 5.1 6.4 7.9 7.1 14.0 4.7 5.1 10.9 10.2 7.3 4.7 11.4 4.6 8.0 8.6 7.3 7.0 8.1 11.5 9.1 6.3 10.8 4.2 9.4 7.0 19.9 4.5 15.7 7.3 10.3 15.9 14.9 7.6 4.7 20.4 11.7 18.3 45.8 27.0 22.6 28.7 25.6 16.6 22.1 18.5 33.1 10.0 51.8 43.3 19.7 19.4 20.3 45.7 19.5 29.0 35.8 49.6 28.3 18.3 39.4 23.0 81.5 37.5 17.2 27.2 24.1 50.4 11.5 20.1 38.6 72.1 12.3 21.0 26.7 56.8 50.2 39.6 36.3 26.1 42.9 23.3 56.6 13.8 19.9 60.8 30.4 20.8 13.3 41.6 48.4 18.9 28.4 19.9 24.4 18.9 17.5 38.3 17.1 33.0 75.7 7.7 44.0 38.7 12.0 11.5 9.0 14.9 15.6 18.0 21.5 15.4 15.9 20.5 23.0 17.8 19.2 2.3 26.7 14.0 17.3 16.2 11.3 4.1 4.1 5.0 5.3 4.2 5.1 4.7 5.1 4.6 4.2 4.5 4.7 22.2 6.4 26.4 5.5 27.5 52.8 32.3 29.5 38.1 10.0 18.9 22.0 22.8 4.3 35.2 7.3 10.4 34.1 25.3 9.9 3.9 15.9 74.8 14.9 28.4 24.8 7.2 17.9 10.2 11.7 34.7 29.8 16.8 19.1 33.6 13.4 19.2 10.2 22.6 5.0 12.0 17.4 20.3 11.2 25.1 12.5 19.9 19.7 17.8 11.2 15.1 8.9 6.2 13.0 8.4 12.2 8.2 19.9 27.0 33.7 7.1 9.3 20.9 13.7 19.7 33.8 23.9 58.9 75.4 33.7 64.8 27.9 29.0 23.9 16.9 23.8 RIT1 "MGC125864, MGC125865, RIBB, RIT, ROC1" ENSG00000143622 "Ras like without CAAX 1" Q92963 1 155897808-155911404 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053249 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "HPA053249: AB_2682089" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (7.27e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-2)" "unprognostic (3.11e-2)" "prognostic unfavorable (8.64e-6)" "unprognostic (3.80e-2)" "unprognostic (4.99e-2)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (2.19e-2)" "unprognostic (9.22e-3)" "unprognostic (4.82e-2)" "unprognostic (3.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.33e-3)" 19.8 13.8 10.7 22.9 12.1 80.7 13.3 12.0 13.0 16.6 12.1 14.0 12.7 14.8 15.4 37.3 10.8 18.5 15.7 10.3 11.8 25.1 12.2 22.7 18.3 13.5 12.7 12.8 13.8 16.5 11.0 23.0 13.3 13.8 14.3 16.0 14.4 18.0 10.8 12.8 12.5 21.3 11.6 21.7 19.7 12.2 12.8 21.5 13.4 16.5 23.6 23.6 21.9 13.3 21.0 22.9 42.3 21.7 21.5 26.6 12.0 37.2 37.4 35.2 35.4 24.1 40.0 9.6 50.0 43.9 25.3 24.7 32.0 18.5 29.4 12.9 16.4 21.0 24.4 15.6 55.7 22.5 37.9 37.1 22.5 40.9 27.4 47.7 48.7 19.7 21.0 26.3 54.3 27.3 30.7 14.9 23.0 36.2 13.9 24.0 33.3 19.6 29.9 44.2 19.7 30.7 27.1 51.1 34.8 76.9 37.3 29.4 62.5 31.7 22.3 27.3 30.7 31.1 30.9 38.8 33.9 22.8 43.0 22.8 41.0 46.9 19.5 25.5 15.6 16.9 16.8 18.5 31.1 17.1 20.2 18.1 106.3 28.8 29.3 12.5 23.8 30.0 10.7 12.1 12.0 13.0 10.3 11.8 13.5 12.7 13.3 11.6 12.8 13.3 45.8 48.1 23.9 12.4 22.4 28.9 36.5 43.7 21.6 8.1 17.4 12.3 14.2 8.6 40.4 18.4 10.4 14.5 41.8 14.1 21.5 39.4 10.4 20.4 25.7 50.5 12.6 16.4 5.1 23.4 16.8 20.8 13.3 32.5 14.0 15.2 24.7 7.0 50.7 6.7 5.3 11.5 42.7 45.6 107.9 10.3 7.2 62.6 33.8 11.2 79.2 25.9 16.5 8.5 8.1 28.3 15.4 15.8 13.4 48.8 15.4 70.6 21.9 11.9 26.3 18.2 26.1 12.7 23.2 26.0 30.7 33.5 32.7 20.7 10.0 79.2 RLF "Zn-15L, ZNF292L" ENSG00000117000 "RLF zinc finger" Q13129 1 40161387-40240921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054653, HPA057300" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA054653: AB_2682557, HPA057300: AB_2683404" "unprognostic (1.71e-1)" "unprognostic (2.24e-2)" "unprognostic (6.46e-2)" "unprognostic (1.88e-2)" "unprognostic (6.78e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (5.84e-2)" "unprognostic (3.43e-2)" "unprognostic (2.18e-2)" "unprognostic (2.60e-2)" "unprognostic (9.38e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (1.86e-1)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.69e-2)" 8.7 4.9 5.5 6.2 6.0 32.8 8.3 12.0 7.9 8.4 2.5 7.6 5.1 7.9 4.7 7.3 7.0 6.6 7.5 6.0 5.6 4.9 7.7 8.2 7.7 4.1 4.3 8.3 5.6 6.5 5.1 7.3 4.2 6.6 5.2 15.4 5.7 5.4 8.5 12.2 6.2 6.1 4.3 6.2 5.7 10.3 5.2 10.2 5.8 7.1 8.5 7.8 8.4 8.2 18.3 6.9 13.3 13.9 11.6 9.4 15.8 6.7 9.9 11.3 14.9 14.0 9.4 18.1 8.6 8.6 8.4 16.8 16.9 11.8 20.4 8.5 11.4 14.9 8.0 8.7 9.2 12.5 8.7 9.3 12.1 12.0 13.5 13.5 7.8 9.8 23.0 10.8 10.4 5.8 10.6 7.5 17.8 6.7 7.9 8.2 21.8 10.6 7.2 18.2 9.4 13.1 12.5 16.5 12.0 20.5 7.8 44.6 6.7 13.2 14.1 11.0 12.6 9.8 9.8 16.6 11.5 11.4 8.4 6.9 1.5 3.0 1.8 2.0 2.4 2.3 1.8 1.9 1.9 2.1 2.3 2.0 3.2 2.4 2.4 0.8 1.8 1.3 5.5 6.0 12.0 7.9 6.0 5.6 4.1 4.3 4.2 4.3 5.2 8.2 36.7 32.1 15.1 52.2 55.8 65.6 50.3 12.7 30.7 17.8 25.5 18.4 16.9 2.8 23.9 3.7 16.7 8.9 40.6 10.4 5.9 13.8 41.3 43.8 41.6 24.9 20.2 11.3 87.1 6.7 10.6 34.9 29.6 56.0 26.6 23.0 16.1 9.0 9.7 26.9 84.7 8.8 14.2 13.8 45.2 8.7 9.0 39.9 17.8 60.9 17.5 14.1 9.2 71.9 89.0 10.1 15.5 7.9 44.6 28.7 8.9 5.5 26.0 17.2 13.1 52.8 36.1 32.2 20.8 29.3 61.1 17.2 45.8 17.0 10.8 33.0 RNF113A "Cwc24, RNF113, ZNF183" ENSG00000125352 "Ring finger protein 113A" O15541 X 119870475-119871733 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000160, HPA076658" Approved Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA000160: AB_1079821, HPA076658: AB_2732319" "unprognostic (2.85e-1)" "unprognostic (4.38e-3)" "unprognostic (5.55e-3)" "unprognostic (2.38e-2)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.65e-3)" "unprognostic (2.02e-3)" "unprognostic (6.29e-2)" "unprognostic (2.57e-1)" "unprognostic (6.49e-3)" "unprognostic (1.83e-1)" "prognostic unfavorable (7.93e-4)" "unprognostic (7.99e-2)" "unprognostic (3.19e-1)" "unprognostic (3.91e-2)" "prognostic favorable (6.23e-4)" 11.0 9.6 11.5 13.0 12.1 35.3 10.2 13.0 14.4 10.5 11.3 11.4 13.2 9.8 9.6 11.3 10.2 8.2 12.7 11.7 13.9 9.2 17.7 11.0 24.7 12.7 13.0 13.4 19.1 9.2 10.0 9.0 13.1 8.9 9.5 15.6 14.4 8.8 12.3 17.1 17.5 7.5 11.9 24.3 12.1 3.4 13.1 24.7 9.9 10.6 19.0 10.8 10.3 12.6 16.9 22.9 11.0 17.7 20.7 14.9 22.3 14.8 25.0 17.6 21.0 19.7 14.1 28.0 28.1 13.8 25.1 20.4 24.4 19.1 13.1 21.9 18.0 17.0 25.8 23.5 28.3 33.7 28.3 18.4 20.6 17.7 26.0 20.7 17.1 19.4 12.2 38.4 17.3 47.5 23.5 39.9 16.1 29.5 32.8 21.7 23.2 45.3 18.5 20.6 14.7 12.9 23.1 35.5 33.1 12.9 8.7 32.9 13.1 18.6 6.6 26.7 29.7 43.2 36.0 27.9 16.8 44.1 12.3 96.4 59.5 109.5 73.9 60.3 74.4 83.6 78.3 79.0 63.4 88.6 81.3 73.1 27.5 65.9 72.6 53.3 96.6 73.6 11.5 12.1 13.0 14.4 11.7 13.9 12.7 13.0 13.1 11.9 13.1 12.6 14.8 9.6 14.8 2.6 42.8 24.3 17.2 26.6 30.7 11.5 13.6 21.1 8.9 18.6 21.4 14.7 14.6 18.5 51.6 10.8 9.8 18.3 0.5 13.1 18.8 17.4 4.2 10.3 3.0 16.8 37.6 15.2 16.3 16.5 26.5 14.4 18.2 13.1 24.4 13.5 4.1 16.8 14.2 17.6 23.1 1.4 12.2 17.0 26.6 5.6 17.2 16.5 39.1 2.0 6.2 15.5 17.8 9.8 59.6 12.3 34.9 25.1 19.6 17.7 6.6 8.3 19.3 2.9 5.8 20.9 24.4 26.4 50.2 15.9 15.5 14.3 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091874-32131561 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0;testis: 119.3" "Group enriched" "Detected in many" 15 "Early spermatids: 982.8;Late spermatids: 3827.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 13.7 7.3 7.6 17.4 9.3 96.0 14.5 13.8 11.9 12.4 10.7 23.5 16.7 14.3 8.5 14.9 19.4 13.6 5.9 6.9 8.7 9.7 21.6 13.3 24.2 8.0 8.6 14.9 16.4 11.2 7.5 15.3 8.5 10.5 20.2 8.9 9.9 7.9 6.9 8.8 17.3 11.6 8.3 21.6 14.2 119.3 8.2 28.9 11.8 6.8 19.8 13.3 8.6 12.4 28.3 16.4 66.4 33.2 8.5 17.5 37.6 28.3 15.8 34.7 39.8 19.4 19.3 67.9 34.3 18.6 22.3 28.9 35.1 31.9 47.1 37.7 58.8 53.5 19.2 24.1 33.3 149.3 45.3 17.1 31.3 38.3 53.8 19.9 35.9 59.3 74.7 27.0 22.7 26.6 101.1 66.5 74.4 48.4 22.6 102.5 41.7 39.3 31.9 20.7 75.0 37.5 37.7 21.7 30.1 30.2 14.0 62.2 27.8 41.5 30.5 10.3 32.2 44.4 64.5 117.9 22.6 81.6 41.5 25.0 64.4 63.3 25.0 48.7 32.2 34.6 54.5 35.9 62.5 39.2 102.8 66.9 64.7 42.8 42.0 26.6 44.3 68.3 7.6 9.3 13.8 11.9 6.9 8.7 8.0 8.6 8.5 8.3 8.2 12.4 27.9 16.0 19.7 15.3 65.9 69.3 33.7 11.8 71.2 6.7 32.4 18.0 8.3 24.3 16.8 16.5 0.0 28.3 51.6 43.0 17.6 17.6 982.8 35.6 20.4 29.4 29.9 48.8 25.9 18.4 21.6 21.3 26.0 28.7 22.8 8.4 22.5 16.8 24.8 8.4 28.0 20.8 20.3 25.5 52.3 3827.9 29.5 34.7 26.6 23.4 27.1 9.9 20.6 22.6 36.4 12.9 23.9 22.2 32.4 32.7 16.4 14.5 23.0 5.2 32.9 23.1 26.0 158.1 128.3 51.4 52.1 8.9 59.3 9.9 29.9 37.5 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474880-124488618 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 93.2" "Group enriched" "Detected in all" 10 "Early spermatids: 810.1;Late spermatids: 992.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 23.5 20.8 10.0 15.9 11.1 93.2 18.9 14.8 12.7 16.6 11.2 15.6 9.2 20.2 13.6 16.5 16.7 16.8 15.3 11.0 11.0 15.3 26.1 16.6 17.3 11.0 10.8 23.6 14.4 11.8 10.2 19.4 11.0 14.9 14.8 12.4 16.5 13.3 20.3 17.2 14.2 20.3 11.8 13.9 13.9 68.7 11.7 19.3 16.3 22.6 14.8 16.7 12.4 15.0 26.6 17.1 21.6 20.3 43.2 34.1 16.6 23.5 44.4 18.6 24.7 10.9 21.6 27.5 27.8 31.7 14.3 19.7 18.3 28.4 28.9 37.6 24.5 41.1 11.9 22.9 33.3 19.6 23.2 30.5 41.0 20.5 55.9 27.1 26.2 26.8 29.1 41.3 22.2 70.2 32.9 13.6 14.3 52.6 25.6 13.2 14.9 27.0 35.3 34.4 9.4 22.3 31.0 76.5 33.4 16.5 35.7 20.7 20.6 13.9 29.7 22.2 26.3 32.9 40.9 28.6 19.9 31.7 13.9 2.7 6.2 10.1 8.7 4.1 11.0 7.9 7.8 10.5 8.4 7.1 8.1 8.4 8.5 7.2 11.4 4.0 11.4 6.7 10.0 11.1 14.8 12.7 11.0 11.0 11.0 10.8 11.0 11.8 11.7 15.0 21.1 3.2 8.4 11.8 66.2 66.2 62.1 27.2 58.6 14.5 31.6 19.7 16.2 34.3 18.5 22.0 6.2 42.3 58.5 22.5 11.7 19.9 810.1 31.3 22.6 24.9 21.7 27.1 12.9 18.0 55.9 40.1 23.4 37.1 20.3 23.2 22.9 31.8 25.0 16.8 12.8 18.5 10.2 33.7 74.4 992.2 29.5 43.4 35.6 12.2 26.5 21.3 26.8 8.5 18.5 22.5 11.4 27.1 35.4 41.1 17.0 16.9 20.1 22.7 19.7 39.7 49.2 62.3 24.3 46.7 70.5 75.5 83.5 22.6 18.2 55.5 RNF168 FLJ35794 ENSG00000163961 "Ring finger protein 168" Q8IYW5 3 196468783-196503768 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 199.9;Late spermatids: 459.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046109 Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA046109: AB_2679540" "unprognostic (6.15e-3)" "prognostic favorable (8.21e-4)" "unprognostic (3.11e-1)" "unprognostic (1.11e-2)" "unprognostic (4.22e-1)" "unprognostic (5.04e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (6.81e-3)" "unprognostic (5.30e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (8.31e-4)" "unprognostic (4.83e-3)" "unprognostic (2.80e-3)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.95e-2)" "unprognostic (6.65e-2)" 8.6 4.8 3.9 6.0 4.2 20.6 6.8 5.9 4.3 9.3 4.4 6.1 6.1 6.0 4.0 7.9 5.9 4.5 6.8 3.2 6.3 4.7 10.4 8.1 7.2 6.1 5.2 7.4 4.8 4.0 3.5 5.4 6.5 5.3 5.7 4.9 5.8 4.1 13.1 11.5 5.6 5.3 4.9 6.8 5.8 10.7 6.0 7.7 4.9 8.3 8.7 6.7 9.3 6.0 21.6 8.5 14.8 19.5 13.6 9.8 21.1 12.9 8.1 8.5 13.3 16.6 10.4 22.7 29.1 10.8 11.9 21.3 21.0 15.4 13.0 10.9 10.3 43.0 22.2 20.7 7.0 13.3 10.3 9.8 5.8 13.3 11.7 6.0 12.6 18.4 13.1 23.1 8.7 36.4 44.6 7.8 17.6 11.6 10.8 19.7 17.2 18.4 7.2 29.2 12.3 12.4 14.6 17.7 11.1 10.9 26.8 11.7 12.4 14.6 11.4 15.7 17.2 19.6 19.7 33.2 14.3 15.8 11.9 30.0 7.3 8.8 12.2 8.0 10.9 6.3 10.1 8.8 6.6 6.6 8.8 9.4 8.0 8.7 12.2 6.2 7.0 7.5 3.9 4.2 5.9 4.3 3.2 6.3 6.1 5.2 6.5 4.9 6.0 6.0 34.4 16.0 37.5 16.0 37.7 100.1 49.8 30.8 52.3 36.0 17.3 15.0 21.7 12.8 20.0 14.7 60.5 14.6 76.4 25.3 17.6 14.0 199.9 17.0 20.8 33.3 14.4 14.1 33.5 8.9 26.6 27.9 23.9 24.0 50.1 24.0 24.3 25.9 17.9 15.2 36.0 18.5 28.5 32.4 98.8 459.7 20.2 33.9 26.6 28.1 38.2 12.7 42.2 25.1 27.4 10.5 17.3 20.7 37.9 27.7 11.4 10.3 17.1 39.8 13.1 23.6 25.7 13.8 54.9 55.5 126.6 10.7 63.7 20.3 22.4 50.3 RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748849-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA047952" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Nucleoli, Nucleoli rim, Cytosol" "HPA038505: , HPA046138: AB_2679553, HPA047952: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (3.86e-2)" "unprognostic (3.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "prognostic unfavorable (8.04e-4)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (2.34e-1)" "unprognostic (9.55e-3)" "unprognostic (1.21e-1)" 4.2 2.8 3.8 6.7 6.2 14.4 5.6 6.2 4.4 5.5 5.4 4.4 4.0 7.6 4.2 10.1 5.6 4.8 3.2 4.0 4.4 4.6 5.0 5.9 6.3 5.4 5.0 7.6 4.4 5.6 2.1 4.7 5.4 5.2 5.3 6.1 4.5 4.3 6.8 5.5 4.4 7.6 4.4 7.3 4.6 2.9 4.6 7.7 5.8 5.8 6.7 5.2 5.4 9.2 10.2 7.7 9.1 9.0 5.8 7.7 3.7 7.9 7.4 8.6 7.4 13.0 7.5 18.2 7.9 9.5 5.8 9.6 12.4 9.3 11.2 9.1 8.0 12.6 15.3 5.1 6.6 6.8 10.1 7.1 7.2 9.8 22.1 9.6 14.0 12.2 11.4 14.1 8.7 8.6 11.6 12.0 3.6 12.9 5.0 10.7 21.7 9.9 5.5 10.6 4.1 7.4 10.6 8.0 16.6 7.3 9.9 8.6 9.4 14.2 11.8 9.0 7.1 10.2 5.8 21.1 2.8 7.3 8.4 1.2 0.5 0.4 0.4 0.3 0.3 0.0 0.4 0.2 0.2 0.1 0.3 0.2 1.4 0.3 0.3 0.2 0.3 0.2 3.8 6.2 6.2 4.4 4.0 4.4 5.4 5.0 5.4 4.4 4.6 9.2 18.8 9.6 11.4 51.6 18.4 19.9 30.6 7.1 20.5 58.2 12.6 9.8 3.0 17.2 8.3 3.7 52.1 5.5 24.6 9.8 5.9 10.2 2.8 30.5 26.7 17.2 12.0 18.3 40.8 11.1 6.4 16.0 14.8 30.1 7.0 24.4 10.8 12.3 8.5 37.0 43.2 8.7 2.0 15.6 19.9 3.1 7.5 16.6 10.6 25.3 12.6 22.9 26.8 42.7 68.7 10.1 6.8 10.5 18.5 49.7 6.3 12.1 8.9 33.7 26.3 31.9 18.7 9.4 11.7 16.4 18.6 8.1 22.2 14.0 10.4 42.2 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Cell line enhanced" "Detected in all" "Daudi: 107.6;Karpas-707: 124.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 14.5 19.1 10.7 24.3 9.6 74.1 10.9 14.5 10.7 16.8 7.6 23.3 25.0 15.0 5.0 35.3 12.3 17.4 10.4 9.9 12.1 21.1 11.3 21.1 17.7 10.7 9.6 9.7 9.2 11.5 7.9 14.9 11.8 11.0 25.8 18.9 15.4 8.9 16.2 22.6 21.7 18.0 11.6 15.1 13.1 79.0 10.8 13.0 9.0 11.1 30.6 30.1 20.9 11.6 18.7 14.3 11.9 11.3 7.1 9.6 79.5 8.5 10.0 14.7 15.6 16.8 54.9 107.6 14.2 10.7 18.2 26.5 14.3 19.8 13.3 39.6 9.5 9.2 10.5 16.9 22.5 14.7 19.0 7.9 36.3 32.5 39.3 17.2 31.9 10.3 11.7 124.8 14.5 6.1 9.6 18.4 19.2 21.1 15.8 12.7 17.3 11.3 11.5 26.4 18.9 9.6 27.0 9.1 63.1 29.1 8.0 20.8 35.1 8.1 11.5 21.1 15.1 29.6 16.1 38.0 11.9 14.7 12.5 6.1 2.0 4.0 1.6 1.9 1.3 1.2 1.4 0.7 1.4 1.5 0.4 0.6 16.9 1.0 1.7 0.6 1.7 0.8 10.7 9.6 14.5 10.7 9.9 12.1 10.7 9.6 11.8 11.6 10.8 11.6 20.6 12.8 4.4 5.5 8.7 46.1 27.0 26.7 24.5 4.6 15.8 11.7 16.2 10.0 9.9 7.3 2.1 12.6 14.6 48.0 1.9 12.9 34.8 25.4 7.3 15.3 11.3 5.2 9.7 11.5 6.3 8.4 13.3 36.9 4.5 3.2 7.1 4.8 13.5 3.3 9.8 22.1 6.1 20.9 37.7 26.3 2.1 42.4 5.4 19.7 39.5 2.8 2.1 7.5 6.6 25.7 31.9 3.8 4.6 34.2 38.6 9.2 14.4 7.7 0.0 5.9 9.6 34.7 16.3 23.9 32.5 7.4 10.3 2.3 16.3 41.7 RNF24 G1L ENSG00000101236 "Ring finger protein 24" Q9Y225 20 3927309-4015558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 112.5;Inhibitory neurons: 127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 238.2" "Lineage enriched" "Detected in all" 10 "granulocytes: 238.2" "Cell line enhanced" "Detected in all" "ASC TERT1: 81.7" "Low region specificity" "Detected in all" HPA011900 Approved Supported "Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA011900: AB_10671089" "unprognostic (6.61e-2)" "unprognostic (6.56e-2)" "unprognostic (1.72e-1)" "unprognostic (1.17e-2)" "unprognostic (8.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.65e-1)" "unprognostic (5.87e-2)" "unprognostic (2.66e-2)" "unprognostic (5.19e-3)" "unprognostic (3.42e-1)" "prognostic unfavorable (2.67e-7)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" 9.0 7.8 9.5 8.0 9.7 51.8 7.0 4.9 10.9 6.6 0.0 5.7 2.5 5.7 14.9 7.5 5.3 5.9 6.5 10.7 9.5 11.3 2.7 13.9 2.3 7.4 7.6 5.1 4.8 2.5 6.2 3.4 7.6 8.7 3.5 4.7 6.9 6.9 2.1 8.8 4.5 5.3 6.6 12.5 5.7 4.1 8.9 5.4 7.3 3.7 3.8 7.9 5.9 7.2 19.8 9.0 12.9 11.2 48.8 81.7 4.6 16.4 35.4 16.5 23.6 6.0 19.3 4.1 3.5 33.7 25.3 12.9 5.2 18.7 27.4 2.8 3.9 36.4 16.2 4.7 42.1 73.8 13.8 27.6 5.7 43.8 36.8 18.3 15.5 12.6 47.1 9.6 26.9 5.2 11.8 15.1 19.5 18.2 12.6 14.0 10.9 3.3 9.3 10.5 12.1 9.8 44.4 26.3 11.6 18.8 9.6 25.3 23.3 39.8 12.9 27.1 19.7 7.5 7.9 1.4 20.2 24.7 12.7 108.9 23.5 51.3 3.7 8.5 3.0 1.4 7.0 5.4 19.3 4.6 4.2 5.4 238.2 7.5 12.7 0.5 3.4 11.5 9.5 9.7 4.9 10.9 10.7 9.5 7.4 7.6 7.6 6.6 8.9 7.2 6.2 3.2 19.1 34.0 7.8 48.8 36.9 24.1 26.2 18.1 26.9 19.3 2.7 4.3 18.6 49.7 16.7 1.9 9.1 5.7 7.9 33.6 16.3 17.2 37.4 13.9 13.1 43.3 112.5 25.6 6.7 42.4 9.7 31.4 4.5 12.6 17.2 1.2 5.7 38.7 127.2 6.6 10.2 24.7 71.6 22.6 36.7 30.9 39.2 16.9 25.2 10.4 7.2 74.4 21.1 29.2 5.8 60.2 5.9 73.8 2.2 1.8 6.8 9.6 19.7 12.4 32.3 21.4 22.4 12.8 54.4 2.9 17.0 7.4 4.8 75.1 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111813 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 406.2;Late spermatids: 505.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: AB_2679401" "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavorable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 8.0 4.2 3.8 5.7 4.8 18.2 6.0 4.4 3.9 5.3 4.6 5.0 3.6 5.9 4.6 4.2 6.3 4.2 5.5 2.8 3.5 4.4 4.8 7.6 5.5 5.4 4.0 5.4 5.1 2.9 2.9 4.4 4.9 4.4 3.2 4.8 4.4 3.4 2.6 3.7 5.2 3.2 4.4 6.2 5.8 2.6 4.5 5.5 4.5 1.9 4.2 6.6 5.4 5.3 6.5 3.9 3.9 3.8 7.2 7.7 6.3 8.9 4.3 3.9 4.2 6.6 2.7 8.0 6.2 10.5 2.1 5.2 3.6 5.2 7.8 11.4 4.1 6.4 7.3 2.9 3.6 17.9 9.6 5.6 4.6 5.8 4.7 3.2 6.0 3.1 3.7 7.9 4.6 4.1 8.5 3.8 3.2 4.3 6.6 11.9 4.5 3.1 3.7 5.9 4.5 3.5 7.1 4.6 3.6 3.4 4.6 6.7 9.9 7.7 6.4 7.1 7.2 10.7 5.3 9.0 5.8 7.5 4.8 3.0 5.0 6.8 5.0 3.2 4.0 3.9 3.6 3.8 4.2 5.0 3.5 3.5 18.0 2.8 4.0 5.5 3.6 2.5 3.8 4.8 4.4 3.9 2.8 3.5 5.4 4.0 4.9 4.4 4.5 5.3 98.2 96.1 88.7 64.6 112.6 46.3 60.4 30.7 43.9 100.4 32.2 35.6 138.6 28.6 61.4 33.1 131.3 57.5 136.9 36.6 15.6 62.5 406.2 64.8 86.9 94.4 99.0 47.9 81.3 38.0 64.9 78.4 62.7 73.8 72.7 68.5 60.0 47.4 60.3 60.6 74.2 45.8 40.7 135.3 126.7 505.0 97.6 166.2 65.8 106.8 137.1 52.3 204.9 87.0 140.0 70.9 62.8 138.8 83.2 63.2 32.3 21.0 44.6 128.6 170.9 81.4 197.6 107.4 80.9 38.7 36.7 43.0 127.4 70.5 38.9 73.3 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 RSL24D1 "C15orf15, HRP-L30-iso, L30, RPL24, RPL24L" ENSG00000137876 "Ribosomal L24 domain containing 1" Q9UHA3 15 55180806-55197049 "Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062724, HPA063392" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA062724: AB_2684850, HPA063392: AB_2685002" "unprognostic (3.40e-2)" "unprognostic (3.00e-1)" "unprognostic (3.83e-1)" "unprognostic (7.28e-2)" "unprognostic (3.80e-2)" "unprognostic (1.07e-3)" "unprognostic (6.71e-3)" "unprognostic (1.15e-1)" "unprognostic (6.56e-3)" "unprognostic (1.34e-1)" "unprognostic (6.19e-3)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (4.44e-1)" "unprognostic (4.54e-2)" "unprognostic (4.95e-1)" "unprognostic (2.41e-1)" 67.0 62.0 47.9 60.2 50.4 238.6 121.8 59.7 71.1 69.6 43.9 57.9 48.2 89.8 68.7 55.2 59.8 55.2 66.1 50.0 51.9 64.2 73.0 48.3 88.0 49.1 49.1 138.6 77.0 52.5 34.2 45.8 50.1 55.1 53.0 54.1 65.2 49.0 91.2 51.6 48.7 61.8 51.3 52.0 60.3 51.0 49.0 82.2 74.3 74.5 76.6 75.0 46.1 59.9 122.0 115.2 130.2 168.5 95.7 172.4 104.6 126.1 127.5 95.6 117.0 112.2 70.8 361.8 110.5 86.5 100.9 141.4 165.3 137.2 125.9 183.6 104.1 191.3 89.1 148.7 219.6 365.0 121.7 154.1 282.4 98.9 286.0 162.6 120.5 275.2 352.0 256.2 114.3 122.5 202.5 324.3 159.8 246.9 105.9 156.7 162.8 565.2 148.3 108.8 181.0 218.7 57.6 159.2 430.1 100.6 152.3 524.9 90.4 82.1 98.5 99.3 181.6 249.5 420.2 382.3 129.3 353.9 142.4 61.3 99.2 51.1 76.9 101.5 124.8 123.6 115.9 98.2 116.9 98.1 173.9 134.8 24.9 103.3 108.9 90.0 142.4 229.9 47.9 50.4 59.7 71.1 50.0 51.9 49.1 49.1 50.1 51.3 49.0 59.9 146.9 99.3 79.8 6.8 259.2 580.6 425.7 437.4 275.4 85.4 258.9 299.5 69.0 140.2 177.6 84.6 22.9 150.2 219.9 51.2 285.7 182.2 100.6 127.2 177.7 154.9 140.2 189.9 14.8 271.1 247.6 191.9 99.4 126.3 152.8 103.6 114.5 64.0 143.1 15.2 15.2 128.0 197.4 212.2 414.4 40.8 203.5 164.2 284.6 11.2 247.2 91.0 170.0 8.5 13.9 218.9 118.2 149.3 174.8 347.4 114.6 355.1 105.0 62.8 157.8 274.6 215.6 116.9 151.8 173.3 522.2 174.4 251.7 118.3 144.3 332.5 RSRC2 FLJ11021 ENSG00000111011 "Arginine and serine rich coiled-coil 2" Q7L4I2 12 122503454-122527000 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040070, HPA048183" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA040070: AB_10673430, HPA048183: AB_2680302" "unprognostic (4.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-2)" "unprognostic (1.44e-1)" "unprognostic (6.42e-3)" "unprognostic (6.90e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (2.74e-2)" "unprognostic (3.26e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.23e-2)" "unprognostic (8.87e-2)" "unprognostic (4.84e-2)" "unprognostic (1.53e-2)" 12.6 12.2 11.5 11.0 11.4 65.7 13.2 17.6 18.4 14.6 11.3 13.9 8.6 14.1 12.5 17.4 12.3 13.6 13.1 11.3 15.3 16.3 11.4 13.8 16.8 12.1 13.7 16.4 13.8 8.0 14.5 13.3 11.7 12.7 12.0 17.1 12.6 9.5 28.5 12.7 12.5 8.8 7.7 11.6 10.8 14.0 11.8 13.2 15.4 16.1 10.7 14.0 15.0 14.0 21.4 24.8 23.2 9.5 18.4 11.2 16.9 38.8 12.0 16.0 8.7 35.5 8.6 24.4 32.0 13.3 9.7 13.3 25.9 10.8 15.7 22.8 23.9 42.1 32.0 38.3 10.1 37.0 24.8 14.5 12.3 13.6 23.2 20.1 11.6 10.7 27.8 14.6 14.1 16.3 26.8 27.8 19.6 17.8 19.6 19.6 20.9 15.9 21.1 39.8 18.4 16.7 29.6 10.0 22.0 23.1 15.9 13.4 18.1 16.5 20.3 18.4 21.7 16.7 42.8 39.5 9.8 21.6 9.4 27.5 17.7 25.4 17.2 14.7 14.3 28.3 15.3 13.9 18.0 33.4 19.3 15.4 18.7 18.3 22.2 17.0 22.4 12.3 11.5 11.4 17.6 18.4 11.3 15.3 12.1 13.7 11.7 7.7 11.8 14.0 176.8 86.6 102.0 44.7 208.7 202.3 376.1 94.0 118.4 114.3 155.6 146.0 103.3 104.4 107.1 93.8 79.2 149.1 219.3 193.5 195.6 109.3 247.3 223.6 218.6 141.7 156.3 143.1 39.1 97.2 183.8 169.3 89.7 238.0 216.5 127.5 84.9 113.7 94.3 149.7 39.9 185.7 101.7 87.6 184.9 107.1 119.9 139.0 126.3 35.6 107.0 132.9 133.9 34.2 49.6 107.3 171.0 105.7 134.2 219.0 110.1 132.7 128.5 131.0 124.9 194.8 176.7 229.2 165.3 116.0 187.0 280.1 210.3 107.6 154.8 287.1 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 SCLT1 "FLJ30655, hCAP-1A" ENSG00000151466 "Sodium channel and clathrin linker 1" Q96NL6 4 128864921-129093600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 110.0;Excitatory neurons: 111.1;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 109.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 66.0" "Group enriched" "Detected in all" 5 "granulocytes: 66.0;monocytes: 31.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036560, HPA036561" Approved Uncertain Microtubules,Cytosol NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Microtubules, Cytosol" "HPA036560: AB_2675190, HPA036561: AB_10673658" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-2)" "unprognostic (5.05e-2)" "unprognostic (9.18e-2)" "unprognostic (1.33e-3)" "unprognostic (1.64e-2)" "unprognostic (1.94e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-1)" "unprognostic (3.09e-2)" "unprognostic (5.34e-4)" "unprognostic (6.54e-2)" "unprognostic (2.70e-1)" "unprognostic (6.05e-2)" "unprognostic (8.92e-2)" 3.6 3.0 3.7 6.4 4.5 14.4 3.5 7.4 4.8 3.7 0.9 3.7 4.3 3.5 2.2 3.9 3.1 4.6 3.6 2.4 2.8 2.7 3.5 3.5 7.3 4.5 4.3 4.5 3.3 2.9 2.9 4.6 3.5 2.4 4.4 2.9 2.6 2.7 1.5 3.2 3.4 3.6 4.7 7.5 3.5 4.9 5.3 8.8 3.0 1.8 6.7 4.4 3.4 3.9 19.9 5.3 18.8 12.4 6.5 10.5 10.3 16.5 14.8 17.8 16.3 5.7 17.1 17.0 10.4 9.3 12.4 7.4 12.5 12.2 18.5 38.9 10.0 22.7 10.2 6.5 8.9 27.1 17.0 6.7 4.3 14.2 14.2 8.5 14.0 8.6 25.7 39.8 15.6 8.8 20.8 13.0 8.4 14.2 10.5 12.2 19.2 10.6 11.4 5.5 28.1 8.2 12.7 11.5 11.1 8.2 6.8 10.8 13.2 14.5 17.6 19.7 22.3 19.3 15.5 29.0 8.1 29.7 22.2 18.3 16.9 36.8 3.8 24.6 2.2 3.9 2.6 2.7 9.5 3.7 2.5 3.4 66.0 10.2 31.1 4.4 3.7 6.5 3.7 4.5 7.4 4.8 2.4 2.8 4.5 4.3 3.5 4.7 5.3 3.9 16.1 12.8 9.8 110.0 18.0 11.1 8.9 5.8 8.0 15.2 6.1 7.4 21.2 15.7 9.0 1.8 29.2 13.8 34.8 9.1 3.9 6.5 63.2 20.3 18.4 11.9 5.4 9.0 111.1 6.3 21.5 16.3 28.1 14.3 12.0 16.5 9.3 1.6 13.3 16.8 116.0 8.1 8.2 21.6 18.0 51.8 10.8 28.4 8.8 87.1 33.8 8.9 82.4 109.1 90.5 9.0 9.8 9.1 24.0 2.7 8.2 3.1 16.7 21.6 13.1 14.4 16.5 19.6 12.1 13.1 13.9 9.3 21.2 30.5 10.6 5.6 SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: AB_10599192, HPA031255: AB_10601462, HPA031256: AB_10603568" "unprognostic (9.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.63e-2)" "unprognostic (1.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.01e-2)" "unprognostic (1.41e-3)" "unprognostic (3.90e-2)" "unprognostic (3.51e-1)" "unprognostic (3.98e-2)" "unprognostic (3.84e-2)" 17.4 8.5 5.5 11.3 7.0 32.9 11.8 6.4 6.6 9.0 4.8 8.3 9.0 11.8 7.8 9.6 7.4 10.5 7.7 4.9 6.0 9.2 14.6 9.2 12.4 6.9 6.6 10.2 9.6 11.1 4.4 11.8 6.6 9.8 9.1 5.1 6.7 7.3 12.7 10.8 9.0 9.8 6.6 10.4 7.7 8.3 6.1 22.8 12.5 9.6 10.6 11.6 7.8 8.4 13.1 9.3 14.9 15.9 10.2 11.3 18.5 13.7 12.9 18.4 14.0 13.7 14.7 19.2 20.9 11.6 7.2 16.5 18.9 11.9 22.2 14.7 15.3 21.1 7.9 12.7 18.6 21.0 24.6 12.5 16.9 19.6 24.6 10.3 12.8 22.6 39.3 22.6 13.7 3.8 29.5 16.6 20.8 20.2 9.8 24.4 19.1 24.9 11.1 9.2 13.3 22.0 15.6 16.9 26.3 11.9 16.6 25.4 12.7 15.6 11.0 20.3 30.4 13.4 10.3 23.4 16.1 12.9 31.5 21.8 6.3 5.9 8.0 6.4 10.8 8.0 8.1 7.8 7.1 7.0 8.1 7.7 18.5 13.5 7.9 8.1 6.7 6.9 5.5 7.0 6.4 6.6 4.9 6.0 6.9 6.6 6.6 6.6 6.1 8.4 36.0 28.9 22.6 4.2 39.9 43.6 17.2 11.2 29.0 6.2 19.8 13.6 9.4 2.8 20.1 9.2 0.0 9.6 29.3 14.3 15.6 6.5 72.8 24.8 15.1 24.8 17.4 56.2 4.7 7.1 10.2 17.8 13.3 35.9 35.5 9.7 12.8 20.6 11.1 15.2 5.0 10.8 16.2 16.4 28.8 20.4 9.9 27.0 19.6 1.9 7.4 12.6 10.3 4.5 8.6 9.7 9.4 6.4 26.6 14.2 9.5 12.7 12.7 8.9 6.6 28.8 23.9 23.9 14.4 26.5 59.1 14.2 23.2 21.0 9.9 18.2 SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1424.3;Pancreatic endocrine cells: 1067.8;Urothelial cells: 984.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.3;OE19: 162.5;U-937: 144.9" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" 36.6 54.4 10.7 69.7 14.4 466.8 25.0 11.1 14.0 55.6 17.3 77.7 140.4 15.6 22.2 478.3 35.8 57.4 26.8 10.7 12.7 33.2 32.1 81.7 51.3 15.1 13.0 18.1 232.1 29.8 32.9 27.0 14.6 15.9 87.5 13.4 99.6 16.9 54.2 15.8 107.3 24.9 13.6 67.4 97.9 7.1 13.7 31.9 30.7 22.9 122.8 88.6 112.4 14.8 42.9 49.7 2.7 0.3 10.6 21.8 41.2 11.8 36.1 14.5 26.1 47.1 125.3 0.3 86.6 26.6 15.6 26.8 4.8 11.4 11.1 59.4 7.5 76.6 16.0 37.0 37.2 13.5 46.2 26.8 18.4 7.3 3.3 7.2 48.7 0.0 27.1 9.9 13.4 19.9 1.7 35.4 4.5 162.5 22.1 3.9 0.5 44.4 51.0 9.3 8.8 4.8 28.8 11.2 64.2 5.9 5.6 43.2 29.1 4.6 10.4 10.2 3.6 0.1 2.2 0.5 17.4 144.9 2.4 118.0 207.1 109.4 53.3 103.7 45.8 43.5 48.1 48.4 150.4 32.3 47.4 50.6 182.3 85.1 82.8 48.6 58.5 175.8 10.7 14.4 11.1 14.0 10.7 12.7 15.1 13.0 14.6 13.6 13.7 14.8 79.9 240.4 269.9 0.7 90.7 35.1 165.1 699.1 38.1 4.2 55.0 51.2 17.6 72.9 420.9 46.0 2.1 124.5 120.8 264.1 56.7 490.3 1.7 210.6 28.7 118.9 96.3 176.3 0.9 1424.3 149.1 89.1 345.1 104.5 452.2 32.1 124.9 20.2 183.0 10.1 0.9 263.1 109.9 332.7 308.2 3.5 34.8 387.3 71.2 15.9 589.7 48.3 139.0 4.5 6.6 1067.8 308.4 27.8 65.2 147.5 333.7 81.3 343.8 17.2 13.1 109.7 67.2 2.0 11.2 461.5 38.1 99.7 112.9 59.2 242.6 984.3 SERTAD2 "KIAA0127, Sei-2, TRIP-Br2" ENSG00000179833 "SERTA domain containing 2" Q14140 2 64631621-64751005 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 85.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 177.6;Basal squamous epithelial cells: 153.1;Suprabasal keratinocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019021, HPA020904" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019021: AB_1856740, HPA020904: AB_1856741" "unprognostic (1.40e-2)" "unprognostic (7.41e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.15e-2)" "unprognostic (8.15e-2)" "unprognostic (3.39e-3)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (5.95e-3)" "unprognostic (1.98e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.21e-3)" "unprognostic (6.78e-2)" "unprognostic (4.98e-2)" "unprognostic (3.84e-1)" 14.1 6.7 4.3 13.8 5.8 85.7 9.4 5.3 5.5 12.7 3.8 8.5 6.2 8.6 7.9 22.8 6.9 9.4 10.3 5.0 4.5 7.5 14.6 9.7 19.2 6.3 5.9 13.5 6.6 10.7 3.6 12.6 5.8 9.3 8.7 15.6 11.7 8.5 8.6 18.8 9.0 8.1 5.4 19.3 9.2 7.2 5.3 35.3 8.1 9.6 27.3 15.9 16.8 7.1 30.9 9.0 16.5 16.6 13.9 35.2 18.9 24.2 23.2 14.1 13.2 23.1 23.0 26.0 13.0 39.8 19.6 12.0 10.9 14.8 29.6 2.5 16.4 17.2 8.8 16.8 3.1 15.3 8.4 24.0 19.1 32.2 20.9 21.1 8.6 12.7 10.9 14.1 33.2 7.4 16.5 16.7 9.0 16.9 23.6 14.3 28.2 10.2 19.1 28.0 19.1 7.5 17.1 11.9 31.5 15.3 7.9 12.1 26.1 75.7 39.1 44.8 19.9 24.0 9.8 29.6 28.0 27.7 30.3 1.3 1.6 2.3 0.9 1.5 0.5 2.5 0.9 1.0 1.5 2.5 2.2 1.6 2.0 1.5 1.8 4.9 0.5 0.9 4.3 5.8 5.3 5.5 5.0 4.5 6.3 5.9 5.8 5.4 5.3 7.1 25.6 6.4 23.6 22.9 40.8 177.6 40.9 22.5 153.1 24.8 28.7 28.6 26.4 32.9 25.9 9.2 18.8 38.6 33.0 31.6 1.9 12.8 51.2 57.8 18.5 35.4 11.3 26.5 27.3 10.0 42.8 35.1 17.3 97.7 8.8 4.8 25.4 24.1 23.6 10.1 19.8 17.1 18.3 39.3 84.7 35.4 17.1 43.6 39.2 38.4 27.4 20.0 14.4 19.6 35.5 20.7 45.4 10.5 28.1 43.9 11.6 9.5 24.9 24.3 13.1 26.8 31.0 10.8 6.7 135.4 148.3 60.1 25.5 3.7 13.3 71.5 SF3A1 "Prp21, PRPF21, SAP114, SF3a120" ENSG00000099995 "Splicing factor 3a subunit 1" Q15459 22 30331988-30356919 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000690, HPA030083" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA 87000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA000690: AB_1079933, HPA030083: AB_10602183" "unprognostic (8.61e-2)" "unprognostic (1.60e-1)" "unprognostic (3.21e-2)" "unprognostic (7.54e-2)" "unprognostic (5.06e-3)" "unprognostic (1.79e-1)" "unprognostic (5.54e-3)" "unprognostic (3.30e-1)" "unprognostic (3.83e-1)" "unprognostic (2.59e-1)" "unprognostic (2.58e-1)" "unprognostic (3.26e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" "unprognostic (1.13e-1)" 36.2 29.7 14.1 45.4 19.0 58.0 35.0 19.2 20.5 33.4 12.6 31.2 29.8 36.3 20.5 34.0 31.8 21.3 28.0 15.3 12.7 25.5 27.5 31.0 44.1 16.6 14.8 46.4 32.9 42.8 24.3 29.0 14.1 29.4 27.0 36.4 33.3 28.1 51.1 40.5 32.8 29.9 13.3 42.0 31.8 49.2 15.9 42.6 31.6 25.8 41.4 33.2 32.8 20.7 86.2 58.9 79.4 77.6 46.4 41.3 94.8 66.5 42.7 71.4 52.8 78.8 55.9 106.4 44.6 47.7 55.9 80.4 101.6 70.8 77.7 97.4 88.4 99.3 69.1 65.3 41.8 202.1 106.3 41.7 49.6 89.5 72.4 40.1 52.1 56.6 112.5 108.0 52.8 49.1 99.4 46.2 132.0 65.7 48.4 139.5 99.4 86.8 40.9 93.6 82.2 74.9 84.4 50.8 78.4 52.5 62.3 65.4 72.9 90.2 80.0 65.1 124.4 83.2 108.2 106.9 69.4 73.8 95.0 6.7 8.9 14.1 10.9 9.8 11.2 10.4 11.0 11.8 9.2 11.0 12.0 11.2 14.1 11.0 13.0 5.6 14.5 8.0 14.1 19.0 19.2 20.5 15.3 12.7 16.6 14.8 14.1 13.3 15.9 20.7 32.4 57.7 66.5 12.1 60.8 26.1 25.4 19.0 37.0 17.6 25.7 24.4 27.6 34.3 30.5 31.3 16.7 32.5 49.2 30.8 17.6 25.7 106.1 30.5 23.1 32.6 25.1 36.1 7.5 29.4 39.7 29.1 35.2 29.1 52.6 76.3 28.2 28.4 40.6 26.9 9.4 30.7 16.2 37.2 28.3 116.8 35.1 39.8 17.8 5.6 58.5 27.1 46.4 6.0 7.1 28.8 31.3 37.6 45.5 26.4 31.8 17.0 39.4 20.3 46.0 29.0 27.3 64.3 41.6 37.8 27.3 34.6 55.8 26.7 33.9 25.8 SF3B4 "Hsh49, SAP49, SF3b49" ENSG00000143368 "Splicing factor 3b subunit 4" Q15427 1 149923317-149927803 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028578, HPA064660" Approved Approved "Nuclear speckles" NA NA 36000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028578: AB_10601601, HPA064660: AB_2685314" "unprognostic (2.43e-1)" "unprognostic (6.58e-2)" "unprognostic (2.49e-2)" "unprognostic (9.26e-3)" "unprognostic (2.74e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (6.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.74e-7)" "unprognostic (9.63e-2)" "unprognostic (6.54e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" 35.6 36.8 27.9 42.3 28.4 74.3 31.6 30.1 35.8 36.0 29.3 55.8 39.6 48.5 37.5 45.1 51.8 33.8 28.9 28.6 30.4 29.9 27.1 36.8 48.5 31.1 28.3 47.5 34.6 53.4 26.0 40.1 28.7 32.3 44.2 20.8 40.1 47.9 22.5 62.4 40.1 46.7 28.0 39.4 32.4 46.4 29.1 58.0 39.1 26.9 57.6 50.3 33.4 29.8 153.0 144.1 119.4 110.9 75.5 58.4 172.0 119.0 118.2 188.0 143.0 152.0 125.6 144.2 87.1 139.7 103.0 154.3 150.9 158.2 161.8 95.3 110.7 130.0 77.3 112.8 121.7 156.6 163.5 74.7 122.6 184.0 84.5 59.0 94.6 126.7 116.6 119.6 172.9 456.6 203.9 148.9 199.4 175.9 146.1 157.9 106.4 157.6 137.4 128.2 79.6 147.6 109.8 151.1 92.5 141.4 229.9 205.1 78.3 154.9 170.0 122.9 222.8 169.0 259.4 161.2 124.2 133.8 147.5 70.5 81.1 130.5 84.0 109.8 87.4 80.2 79.6 90.4 71.3 73.1 74.3 71.9 111.2 104.7 120.0 84.6 100.1 67.5 27.9 28.4 30.1 35.8 28.6 30.4 31.1 28.3 28.7 28.0 29.1 29.8 30.4 16.0 13.4 4.2 39.9 54.2 47.5 83.2 65.4 20.0 34.3 41.4 3.9 21.5 41.2 23.9 4.2 80.8 54.2 42.2 60.7 64.3 80.3 38.9 30.4 30.6 26.0 34.3 4.1 51.6 77.5 31.8 27.0 44.5 39.3 32.9 16.8 14.7 53.0 8.4 4.8 40.0 59.0 24.7 42.5 13.3 45.1 34.9 24.9 3.7 61.8 27.5 44.3 4.5 7.0 62.3 35.9 29.3 38.6 32.2 28.5 43.0 49.8 15.9 46.0 30.8 64.6 64.0 51.5 47.0 51.3 94.7 44.9 27.9 36.7 43.8 SF3B6 "CGI-110, Ht006, P14, SAP14a, SF3B14a" ENSG00000115128 "Splicing factor 3b subunit 6" Q9Y3B4 2 24067586-24076373 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034829, HPA034830" Enhanced Supported Nucleoplasm NA NA 11000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA034829: AB_10673104, HPA034830: AB_10669680" "unprognostic (6.37e-2)" "unprognostic (1.38e-1)" "unprognostic (3.59e-1)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (5.35e-3)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.74e-2)" "unprognostic (8.75e-2)" "unprognostic (7.41e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-1)" 79.0 86.5 82.4 65.1 84.1 211.2 137.9 86.4 125.3 99.1 82.5 106.2 91.1 84.7 141.9 123.5 89.2 78.2 89.3 82.7 85.7 111.5 132.6 67.3 102.8 85.9 84.2 93.7 63.7 103.0 62.9 88.3 86.3 81.2 108.7 64.4 71.6 84.2 74.7 76.4 84.7 89.0 88.6 65.1 70.4 66.6 82.0 138.6 104.9 106.2 123.3 117.2 85.2 92.4 307.2 152.4 231.6 207.9 182.7 292.8 139.3 233.6 253.8 279.1 284.2 329.9 197.0 236.6 117.3 213.1 265.4 187.7 245.2 293.7 345.5 218.0 263.4 256.6 197.2 299.4 324.4 314.3 151.3 268.5 342.5 281.3 319.3 286.4 288.8 199.4 290.2 181.3 294.2 250.3 234.1 486.1 194.7 362.8 264.0 170.6 327.7 239.1 334.6 189.0 214.4 320.7 123.6 268.3 570.9 195.4 122.7 309.4 173.9 159.6 213.6 157.3 384.4 171.2 239.1 655.3 215.4 515.8 224.5 225.0 118.9 185.7 96.0 133.5 108.1 153.9 122.9 117.8 138.9 114.7 118.0 130.0 173.5 133.7 124.3 129.6 179.6 143.8 82.4 84.1 86.4 125.3 82.7 85.7 85.9 84.2 86.3 88.6 82.0 92.4 207.4 70.5 91.5 11.8 125.1 0.0 280.4 0.0 208.3 50.7 194.3 320.5 120.8 133.0 55.1 138.0 16.7 296.5 149.2 217.1 389.4 206.1 195.9 226.4 208.1 149.0 180.3 164.7 9.2 167.4 413.2 153.0 85.6 210.7 100.1 185.1 142.1 167.1 232.7 18.5 10.2 253.5 0.0 129.3 0.0 49.4 210.3 132.6 0.0 10.3 227.4 175.4 149.3 11.6 19.4 205.4 314.5 180.5 134.0 327.5 381.2 423.1 78.0 68.4 118.3 155.0 158.9 272.4 173.7 257.8 0.0 271.7 126.6 344.4 242.7 438.1 SFPQ "PPP1R140, PSF" ENSG00000116560 "Splicing factor proline and glutamine rich" P23246 1 35176378-35193145 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009886, HPA047513, HPA054689" Enhanced Enhanced Nucleoplasm NA NA 640000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009886: AB_2186937, HPA047513: AB_2680073, HPA054689: AB_2682574" "prognostic favorable (9.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (5.53e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (7.91e-13)" "unprognostic (3.10e-1)" "unprognostic (4.00e-3)" "unprognostic (3.85e-2)" "unprognostic (2.20e-2)" "unprognostic (8.03e-3)" "unprognostic (1.25e-3)" "unprognostic (1.16e-2)" "unprognostic (3.97e-3)" "unprognostic (3.07e-1)" "unprognostic (3.77e-3)" 62.9 46.7 25.1 62.1 26.0 215.1 53.2 38.5 32.3 54.0 23.4 46.9 44.6 60.2 51.0 59.8 54.6 39.9 43.8 24.8 30.7 48.8 50.6 40.8 76.4 30.2 27.2 74.4 52.8 44.9 34.4 51.8 25.2 49.8 54.4 47.4 52.8 35.6 63.9 60.0 47.6 52.9 23.0 54.1 48.0 45.8 24.9 85.5 44.8 27.4 94.5 58.1 52.5 44.6 180.5 147.3 251.1 142.9 60.5 90.0 234.7 96.1 97.1 160.4 116.3 161.5 126.4 325.6 130.1 111.8 100.6 160.4 276.1 188.3 217.0 175.2 183.0 245.5 156.2 193.6 81.5 258.2 140.1 72.4 71.7 139.4 67.3 70.9 142.3 169.1 282.6 150.9 158.3 156.8 304.2 220.1 299.7 107.8 140.7 304.5 170.4 213.6 156.2 214.4 180.1 200.3 138.6 106.3 147.1 174.4 125.0 181.7 152.3 127.7 188.3 84.7 208.9 171.2 156.5 327.6 91.1 168.6 185.9 2.6 4.1 3.0 4.7 5.8 5.4 4.1 4.6 3.8 3.8 4.5 4.3 4.8 2.1 3.4 4.7 7.3 5.6 2.3 25.1 26.0 38.5 32.3 24.8 30.7 30.2 27.2 25.2 23.0 24.9 44.6 286.7 169.9 237.7 149.8 317.4 357.5 239.3 80.6 234.5 230.0 231.6 191.0 149.6 82.9 146.2 110.3 191.8 206.5 339.0 149.7 82.2 120.1 126.8 230.1 318.9 222.2 219.6 198.9 127.3 138.4 222.9 255.8 267.6 333.1 155.8 450.5 123.5 109.1 141.4 171.6 143.4 189.5 59.0 129.4 216.9 361.9 142.9 258.5 140.5 104.9 146.2 152.6 127.7 248.8 183.1 162.0 126.7 116.6 291.8 159.9 94.8 87.6 114.8 223.6 52.6 530.6 259.2 199.1 171.9 287.9 327.3 305.5 313.7 223.7 220.0 167.7 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC20A1 "Glvr-1, GLVR1, PiT-1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 353.3;Paneth cells: 261.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 522.4;U-87 MG: 507.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834" Approved Approved "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB019279: , HPA035834: AB_2674809" "unprognostic (1.81e-1)" "unprognostic (2.18e-1)" "unprognostic (5.38e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.50e-2)" "unprognostic (3.38e-2)" "unprognostic (2.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.43e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.44e-5)" "unprognostic (6.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-3)" 36.1 11.7 16.2 33.2 24.3 74.6 15.6 27.8 26.3 11.8 25.0 53.6 14.4 13.7 8.4 15.0 14.5 26.4 21.8 20.7 19.8 22.1 49.0 29.2 37.1 25.5 20.7 9.2 30.7 10.4 15.9 29.7 25.2 13.3 21.9 52.3 12.8 9.3 19.7 14.5 28.4 15.0 18.6 29.5 20.2 15.7 24.5 27.2 15.9 7.5 27.5 40.8 13.3 21.2 69.0 55.5 71.1 57.8 52.9 128.8 54.4 181.6 215.3 79.1 102.2 85.0 164.9 124.0 97.5 67.7 305.0 70.5 78.8 138.0 114.8 68.5 80.4 105.5 57.1 81.3 78.2 61.2 178.9 66.0 53.8 279.1 193.9 522.4 102.2 52.9 199.5 126.3 346.7 26.8 83.9 235.9 119.3 31.8 147.6 77.8 63.5 34.9 114.5 312.8 64.4 60.8 91.7 54.9 127.9 31.4 56.0 42.9 223.6 143.5 94.7 50.8 142.4 52.1 143.7 102.2 507.2 57.9 178.3 13.4 33.5 30.1 52.8 59.8 59.4 8.3 22.2 38.4 25.4 5.0 17.5 27.6 14.7 50.2 37.2 41.8 14.6 33.9 16.2 24.3 27.8 26.3 20.7 19.8 25.5 20.7 25.2 18.6 24.5 21.2 61.7 12.8 25.9 42.4 40.3 112.8 59.1 38.7 104.7 60.0 41.9 31.6 49.6 32.9 35.3 9.2 210.6 44.7 119.1 353.3 13.7 18.1 1.5 86.0 34.3 48.2 35.7 53.2 47.3 14.0 13.5 61.5 96.4 167.8 25.3 20.6 41.0 58.1 28.2 20.2 27.2 85.8 32.6 58.5 86.2 3.3 3.7 80.5 26.6 19.7 42.8 31.8 66.9 18.6 26.1 26.9 261.6 4.9 59.8 34.0 156.3 5.2 59.6 84.6 0.0 36.9 25.9 8.5 18.7 119.5 61.8 74.3 70.4 19.0 96.5 90.3 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLFN13 FLJ31952 ENSG00000154760 "Schlafen family member 13" Q68D06 17 35435096-35448837 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.6;salivary gland: 32.5" "Cell type enhanced" "Detected in many" "dendritic cells: 56.3;Endometrial ciliated cells: 59.9;NK-cells: 60.8;Plasma cells: 38.2;Respiratory ciliated cells: 75.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 5.3" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;NK-cells: 5.3" "Cell line enhanced" "Detected in many" "EFO-21: 38.9;HL-60: 131.9;REH: 75.0;U-266/70: 63.2" "HPA022532, HPA023064" Uncertain Approved "Cytokinetic bridge" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Cytokinetic bridge" "HPA022532: AB_1856615, HPA023064: AB_1856616" "unprognostic (1.11e-1)" "prognostic favorable (3.82e-4)" "unprognostic (4.73e-2)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (5.74e-2)" "unprognostic (9.38e-3)" "unprognostic (1.32e-2)" "unprognostic (3.34e-1)" "unprognostic (3.55e-1)" "unprognostic (5.06e-3)" "unprognostic (2.33e-1)" "unprognostic (1.33e-1)" "unprognostic (3.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" 3.1 0.9 1.5 9.1 1.1 25.6 9.9 1.2 0.9 6.2 5.7 5.8 8.5 4.8 2.9 3.5 16.9 6.6 1.8 1.0 1.2 2.6 2.1 6.4 10.5 1.3 1.4 1.1 3.2 14.5 0.5 1.9 1.2 2.1 6.5 0.1 32.5 4.2 0.7 2.3 4.5 4.2 1.0 13.7 11.3 0.6 1.2 10.0 7.9 0.8 11.6 2.5 1.5 1.7 0.2 7.0 13.7 0.1 0.4 1.4 0.2 1.7 0.5 6.7 10.6 0.0 0.1 0.0 38.9 1.3 0.3 11.7 1.4 4.9 7.6 3.9 2.2 37.2 6.5 0.1 0.6 131.9 1.0 0.4 0.6 3.6 0.1 0.0 2.2 0.4 0.1 36.8 0.2 0.1 0.9 28.4 6.8 0.0 0.0 75.0 0.5 3.8 11.6 34.1 0.0 0.0 0.0 6.2 0.3 0.9 9.8 20.9 0.3 0.1 2.0 10.1 0.5 63.2 9.5 0.2 0.2 20.9 1.0 3.7 0.2 4.5 1.2 0.3 1.0 0.9 0.5 0.6 0.2 0.9 0.4 0.3 0.8 5.3 0.1 0.1 0.5 0.4 1.5 1.1 1.2 0.9 1.0 1.2 1.3 1.4 1.2 1.0 1.2 1.7 6.2 0.0 3.7 0.0 7.3 1.0 3.1 4.7 5.7 0.2 14.5 9.1 0.8 27.1 12.5 5.5 0.0 0.8 56.3 2.1 1.9 1.2 0.1 59.9 3.6 3.4 3.0 19.1 0.1 0.4 0.4 1.6 8.2 11.7 3.8 3.8 1.8 0.6 1.6 0.0 0.1 4.5 12.2 1.0 1.7 0.0 0.9 3.2 0.0 2.8 1.8 0.2 60.8 0.0 0.1 1.3 0.6 0.4 38.2 1.0 0.5 1.3 75.4 0.2 0.0 0.4 3.8 0.2 0.6 6.7 1.1 0.0 16.6 3.3 4.2 1.4 SMCR8 "DENND8A, FLJ34716" ENSG00000176994 "SMCR8-C9orf72 complex subunit" Q8TEV9 17 18315293-18328056 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021557, HPA024646" Uncertain Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA021557: AB_1857283, HPA024646: AB_1857284" "unprognostic (1.69e-1)" "unprognostic (2.25e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (4.34e-3)" "unprognostic (2.11e-3)" "unprognostic (3.02e-2)" "unprognostic (3.18e-1)" "unprognostic (1.48e-2)" "unprognostic (5.09e-3)" "unprognostic (7.11e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.41e-3)" "unprognostic (4.35e-2)" "unprognostic (1.55e-2)" "unprognostic (9.27e-2)" 5.2 5.0 1.7 5.0 1.9 12.5 5.0 2.2 1.9 4.7 2.6 5.8 3.3 5.3 2.6 5.3 4.8 2.7 4.5 1.8 2.4 4.6 4.0 5.5 5.7 2.0 1.8 4.9 5.1 5.8 5.3 2.9 1.9 4.8 3.7 2.7 6.4 3.0 6.4 5.8 7.2 3.0 1.6 8.4 6.2 4.9 2.2 5.4 4.7 3.5 5.6 5.3 3.9 2.3 7.0 9.6 4.7 5.5 6.5 4.3 8.6 4.9 6.6 8.5 8.1 14.8 2.9 4.1 3.6 6.1 9.6 9.1 9.4 5.8 7.8 8.4 7.9 7.7 10.0 4.2 7.0 3.0 18.1 5.5 7.3 9.8 6.1 5.6 6.1 5.9 6.5 3.8 5.1 4.3 5.1 4.4 4.5 9.0 4.0 5.6 12.1 6.5 3.9 7.9 2.5 5.8 5.6 7.1 10.5 24.7 14.4 6.1 6.1 4.8 5.8 12.8 6.6 5.7 7.0 2.1 6.7 4.7 5.0 2.5 0.5 0.4 0.2 0.3 0.2 0.3 0.2 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.7 0.3 0.2 0.3 1.7 1.9 2.2 1.9 1.8 2.4 2.0 1.8 1.9 1.6 2.2 2.3 5.6 6.4 11.0 2.3 7.0 0.4 3.4 0.0 4.6 6.7 8.2 6.1 3.3 5.7 5.6 11.0 2.1 3.8 6.4 8.2 0.0 5.4 3.3 8.9 9.0 6.3 3.6 5.2 5.1 5.4 2.9 4.6 7.7 13.9 8.8 7.4 10.4 5.3 8.7 6.7 5.5 6.0 0.0 23.5 0.3 2.0 4.1 15.1 0.0 5.6 18.7 2.9 4.1 2.5 3.7 6.9 4.5 4.1 3.5 6.8 6.3 6.4 2.2 5.9 0.0 5.4 4.3 9.3 7.8 3.9 0.6 6.0 6.3 6.2 6.1 7.5 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" Cytosol "HPA046279: AB_2679611, HPA049426: AB_2680762" "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.73e-4)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 9.9 10.8 4.2 11.1 4.9 25.4 10.9 5.3 6.2 15.5 3.1 12.1 9.5 15.5 5.0 13.8 15.9 9.2 11.7 4.0 7.0 8.6 9.2 10.6 15.7 7.5 5.0 14.6 13.3 15.2 22.7 14.9 6.3 11.8 11.1 4.7 12.9 11.7 13.3 13.5 11.5 12.9 2.4 11.2 10.3 17.7 6.0 19.8 16.0 12.0 15.7 11.8 12.3 10.0 89.1 41.5 46.2 39.2 29.1 21.8 58.7 41.5 42.0 76.3 62.8 119.2 47.0 56.2 41.2 49.9 36.3 43.8 64.0 64.4 40.4 72.7 61.2 60.5 36.2 90.1 31.2 68.5 34.7 25.6 39.4 77.0 27.2 21.1 44.9 51.4 82.2 40.8 40.7 44.3 72.2 32.0 77.0 40.1 56.4 74.3 44.2 59.0 27.0 38.6 66.8 36.3 42.8 54.5 22.7 24.9 37.8 34.8 32.8 57.0 49.3 33.0 49.4 34.3 44.0 79.2 51.4 38.7 44.0 1.8 9.2 14.8 12.9 11.2 14.3 8.9 9.6 11.6 9.6 9.1 9.0 10.5 4.3 12.1 8.1 6.0 9.2 10.4 4.2 4.9 5.3 6.2 4.0 7.0 7.5 5.0 6.3 2.4 6.0 10.0 17.4 3.2 11.3 4.9 20.8 15.0 9.1 8.8 12.0 19.8 21.5 23.0 3.9 5.7 8.0 7.3 12.5 23.8 16.4 7.9 9.8 9.2 22.7 16.0 19.7 12.0 13.1 21.2 6.9 12.2 26.5 12.2 18.8 26.3 6.3 29.0 10.4 17.3 14.1 15.2 6.7 12.8 4.1 13.2 7.7 41.7 14.6 10.2 16.0 1.0 8.8 9.9 11.3 7.5 10.4 11.8 10.5 18.4 27.0 9.4 7.7 5.9 9.9 16.0 0.0 14.1 12.8 25.0 25.6 18.7 20.6 15.6 15.6 16.0 15.2 9.6 SNRPB "COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1" ENSG00000125835 "Small nuclear ribonucleoprotein polypeptides B and B1" P14678 20 2461634-2470853 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA003482, CAB009610, HPA067842" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB009610: AB_2193859, HPA003482: AB_1857337, HPA067842: AB_2685909" "unprognostic (2.33e-1)" "unprognostic (3.14e-2)" "unprognostic (5.64e-2)" "unprognostic (2.73e-2)" "unprognostic (9.47e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.07e-5)" "unprognostic (5.11e-2)" "unprognostic (3.66e-1)" "unprognostic (4.66e-2)" "unprognostic (7.30e-2)" "unprognostic (4.20e-2)" "unprognostic (2.21e-1)" "unprognostic (2.79e-1)" "unprognostic (1.13e-1)" "unprognostic (9.18e-2)" "unprognostic (9.47e-2)" 113.4 110.5 45.0 110.7 45.1 345.4 111.6 50.8 54.5 103.7 48.5 108.1 102.6 119.4 66.7 177.1 93.7 62.7 90.1 46.7 47.1 103.6 91.9 111.7 166.7 47.7 45.1 93.8 78.0 83.1 72.5 82.9 47.4 87.9 86.5 25.0 99.7 62.4 112.6 148.5 109.2 85.9 48.6 139.0 100.7 83.2 46.8 168.9 77.1 59.9 154.0 109.3 108.9 50.4 782.5 1063.7 376.7 340.4 83.8 149.1 418.7 334.6 259.8 693.8 556.2 1209.6 555.7 588.8 210.6 203.2 556.7 567.8 370.7 636.2 350.3 239.7 658.6 400.5 190.0 1148.0 290.0 560.3 236.6 171.3 237.9 564.0 252.6 132.2 389.0 491.1 561.0 414.6 288.7 543.0 897.1 916.2 825.2 405.8 520.8 531.3 379.0 711.4 266.8 407.8 405.6 442.7 414.5 554.3 503.2 162.8 524.5 612.9 266.7 404.4 340.9 360.8 764.8 345.5 938.8 877.1 137.7 623.8 419.5 167.9 166.7 133.0 202.8 210.9 170.5 210.7 178.0 179.5 226.7 210.6 144.2 167.5 87.8 166.0 221.6 237.4 241.5 266.0 45.0 45.1 50.8 54.5 46.7 47.1 47.7 45.1 47.4 48.6 46.8 50.4 197.0 44.8 69.1 4.6 206.9 478.6 335.2 309.4 150.2 46.8 156.8 151.8 17.9 112.9 167.3 93.8 12.5 365.2 251.9 163.6 144.8 347.3 17.1 98.3 143.0 202.9 142.0 170.0 6.8 295.8 647.8 155.4 89.2 128.4 144.5 215.0 83.2 60.8 294.8 30.3 6.3 239.4 203.4 102.7 308.3 20.4 159.1 158.0 190.3 6.5 189.5 68.9 265.7 6.0 8.5 404.6 171.9 123.8 176.9 421.8 119.3 143.6 98.9 57.5 157.8 169.6 228.5 329.6 308.3 181.5 423.1 373.4 210.1 306.7 293.5 433.2 SNRPB2 "Msl1, U2B''" ENSG00000125870 "Small nuclear ribonucleoprotein polypeptide B2" P08579 20 16729961-16742564 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 524.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 381.4;SK-MEL-30: 378.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050814, HPA076104" Supported Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "Cytoplasmic bodies" "HPA050814: AB_2681245, HPA076104: AB_2732301" "unprognostic (4.73e-2)" "unprognostic (1.78e-1)" "unprognostic (4.02e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.45e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (6.03e-7)" "unprognostic (4.23e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (1.77e-1)" 27.5 27.6 23.9 30.9 24.9 53.9 31.0 24.3 35.7 22.3 26.0 26.4 24.3 29.0 35.2 20.8 24.4 21.9 25.0 24.9 25.9 42.3 30.1 22.2 43.3 24.9 25.2 29.1 18.3 26.9 22.6 28.7 24.7 21.9 26.5 11.2 21.1 21.6 30.2 17.0 24.6 27.1 25.6 28.4 23.4 22.6 24.7 37.3 25.6 27.2 36.6 28.9 19.8 27.3 76.0 73.3 94.3 59.1 46.1 57.8 104.7 73.4 60.9 78.0 76.1 84.6 83.5 121.0 56.0 63.0 119.2 69.3 74.9 85.5 111.0 40.0 62.8 111.8 22.4 157.4 53.9 132.0 73.8 57.6 56.0 71.5 55.6 58.1 74.4 81.3 93.8 53.6 80.6 79.2 152.5 159.6 84.2 381.4 97.0 86.1 113.1 84.9 76.9 50.8 49.8 142.3 54.5 147.6 378.7 69.4 93.8 106.5 63.7 71.0 71.2 64.4 122.7 46.9 102.8 134.7 33.7 77.8 157.1 51.8 29.4 47.4 27.3 38.6 35.8 31.5 34.7 31.5 31.6 29.1 30.0 33.4 12.8 31.7 40.5 45.9 48.0 29.9 23.9 24.9 24.3 35.7 24.9 25.9 24.9 25.2 24.7 25.6 24.7 27.3 125.9 44.8 58.0 6.2 128.6 89.1 186.9 238.2 60.3 30.7 93.8 118.5 67.4 107.2 126.5 93.8 0.0 281.4 150.1 79.6 215.2 165.9 163.3 105.3 150.3 124.6 93.3 131.7 12.9 169.2 288.3 120.8 50.0 120.5 132.5 103.2 140.3 139.3 227.3 48.8 14.3 133.3 152.5 157.9 124.6 35.1 172.7 120.5 110.3 8.4 195.4 77.7 153.5 15.1 21.5 169.4 102.7 155.7 91.2 143.8 94.9 524.6 107.2 25.1 98.6 118.7 147.5 192.4 130.4 60.8 96.0 376.9 150.1 94.7 127.7 170.2 SNRPF Sm-F ENSG00000139343 "Small nuclear ribonucleoprotein polypeptide F" P62306 12 95858928-95903828 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 486.5" NA NA 47000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "unprognostic (6.86e-2)" "unprognostic (1.70e-3)" "unprognostic (3.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.12e-2)" "unprognostic (3.32e-2)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (2.74e-2)" "unprognostic (6.81e-2)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (8.06e-2)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.52e-2)" 22.5 21.5 19.2 27.4 19.6 47.7 21.9 21.3 28.4 19.7 18.8 26.2 21.7 21.2 15.8 38.2 17.9 8.0 22.8 19.2 21.0 28.4 32.3 19.6 28.2 19.3 20.5 22.7 17.2 16.4 24.5 16.0 19.6 17.4 18.7 18.4 18.3 11.8 24.0 22.3 21.3 14.7 19.7 23.0 19.9 18.6 20.6 36.5 17.5 18.2 24.9 20.1 23.1 19.5 146.0 116.9 129.9 88.7 35.2 34.7 107.2 72.7 50.7 95.9 67.7 169.1 46.9 160.3 68.2 48.8 83.8 97.7 116.9 103.4 78.5 107.3 184.7 154.7 116.1 171.7 43.9 243.4 68.3 35.7 50.1 87.3 83.9 64.2 67.3 176.7 138.7 31.5 52.2 155.3 212.2 486.5 178.1 109.9 258.0 166.4 103.4 118.3 71.9 150.7 129.0 76.2 107.6 102.5 74.2 87.6 105.6 187.4 58.8 52.2 90.0 68.6 144.3 46.2 87.0 232.1 26.0 125.9 66.7 8.4 42.6 20.0 51.4 43.4 69.8 80.2 72.0 63.2 97.8 75.1 77.3 70.7 4.1 65.9 35.8 92.9 68.2 60.7 19.2 19.6 21.3 28.4 19.2 21.0 19.3 20.5 19.6 19.7 20.6 19.5 129.3 51.3 103.2 5.5 150.7 265.2 231.1 272.4 139.5 53.7 188.1 286.3 58.4 124.4 146.5 136.1 31.3 350.9 132.8 142.8 272.0 217.4 76.2 166.0 189.1 151.0 172.8 165.7 6.1 285.9 457.3 128.1 95.3 186.8 106.5 172.1 128.2 338.6 241.1 32.0 6.8 282.2 140.4 128.7 197.9 36.8 134.2 126.9 120.9 3.7 197.1 119.9 146.2 7.1 7.0 236.7 152.5 119.6 98.1 280.1 119.7 272.1 98.2 60.6 92.1 210.5 213.9 200.9 276.0 217.6 265.2 207.8 158.2 152.9 346.3 253.1 SNW1 "Bx42, FUN20, NCoA-62, Prp45, PRPF45, SKIIP, SKIP, SKIP1" ENSG00000100603 "SNW domain containing 1" Q13573 14 77717599-77761207 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002457, CAB009931, HPA017370" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB009931: AB_2302187, HPA002457: AB_1080047, HPA017370: AB_1857339" "unprognostic (1.24e-3)" "unprognostic (2.02e-1)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (4.27e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.07e-1)" "unprognostic (8.09e-3)" "unprognostic (2.88e-2)" "unprognostic (3.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-3)" "unprognostic (1.22e-2)" 47.1 33.3 27.6 33.6 29.5 91.2 42.7 30.6 35.9 39.2 29.1 38.4 32.6 39.0 28.4 38.4 38.3 26.7 39.5 27.0 29.0 38.7 33.6 37.1 46.2 29.5 28.6 41.4 38.6 31.3 30.3 33.0 29.8 32.2 32.1 43.3 34.0 21.9 64.8 50.7 38.5 30.9 28.6 44.6 36.6 48.5 28.4 49.0 33.9 35.9 41.9 38.8 38.0 32.9 91.0 66.6 67.0 70.8 54.5 60.6 76.5 61.3 54.6 66.8 61.2 66.0 81.0 88.3 54.5 46.1 50.8 88.2 81.8 58.9 90.3 71.1 63.5 71.8 59.1 66.7 77.7 50.5 81.0 46.8 76.1 60.0 82.8 71.5 65.8 83.7 103.9 64.7 51.9 93.1 90.7 85.4 74.2 103.1 87.8 97.3 85.5 61.7 61.4 82.6 71.2 76.5 84.7 73.6 87.3 68.1 106.6 95.5 69.9 71.6 81.7 64.9 73.9 62.9 95.5 98.7 65.5 79.8 80.9 94.5 71.0 95.6 57.5 76.9 65.5 59.2 64.5 65.9 72.6 67.0 67.6 63.9 67.8 94.5 92.1 43.2 94.5 76.1 27.6 29.5 30.6 35.9 27.0 29.0 29.5 28.6 29.8 28.6 28.4 32.9 86.5 93.0 49.3 13.1 64.2 56.5 80.4 89.1 33.6 56.0 40.1 50.0 49.9 47.1 77.9 53.3 35.5 79.4 75.4 38.0 76.3 79.0 43.5 97.2 81.3 69.9 43.6 85.0 17.9 70.1 100.1 64.9 26.5 80.5 92.3 61.5 55.6 33.7 76.4 38.7 18.6 50.8 54.9 53.6 52.0 24.0 77.9 70.7 39.2 30.0 95.6 66.7 65.9 15.6 31.9 71.3 43.8 74.1 46.3 48.9 48.8 57.3 88.1 72.2 65.7 60.9 89.5 300.5 140.7 39.7 54.3 109.0 76.8 54.4 47.9 70.9 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPIN4 "FLJ44984, TDRD28" ENSG00000186767 "Spindlin family member 4" Q56A73 X 63347228-63351332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA044559 Uncertain Approved Nucleoli,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Nucleoli "HPA044559: AB_10794171" "unprognostic (9.66e-2)" "unprognostic (2.00e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-2)" "unprognostic (2.31e-1)" "unprognostic (3.12e-1)" "unprognostic (3.22e-4)" "unprognostic (3.30e-3)" "unprognostic (9.44e-3)" "unprognostic (8.62e-2)" "unprognostic (3.65e-3)" "unprognostic (9.39e-2)" "prognostic unfavorable (3.56e-6)" "unprognostic (1.74e-2)" "unprognostic (2.15e-1)" "unprognostic (2.57e-1)" "unprognostic (8.09e-2)" 1.8 1.7 1.4 2.7 1.3 10.2 3.3 0.9 1.7 2.4 1.7 3.6 2.2 3.4 2.3 5.9 2.7 2.1 1.3 1.3 3.1 1.5 1.3 3.1 3.5 1.6 2.0 2.9 1.7 1.7 2.3 4.4 1.6 3.3 4.1 2.0 7.2 1.7 0.5 2.0 2.2 3.5 1.2 2.8 2.2 0.7 2.5 3.1 2.5 0.5 5.6 2.1 2.7 1.8 31.7 8.0 18.2 14.9 3.9 5.5 13.1 15.6 6.5 8.9 10.6 5.4 30.7 0.0 6.7 7.3 10.2 10.3 23.7 11.2 16.2 13.7 7.5 40.5 10.3 4.9 1.7 35.5 30.3 2.6 3.9 14.9 8.0 4.3 9.9 7.0 12.5 38.2 20.4 10.7 11.9 19.0 18.8 5.2 11.5 16.4 39.2 8.7 6.5 8.3 0.1 10.0 27.9 8.1 3.0 37.4 17.4 16.9 4.3 17.9 19.9 29.8 9.8 8.4 10.4 20.5 9.5 28.8 10.7 0.7 0.8 1.6 0.5 0.9 0.2 0.4 0.3 0.3 0.6 0.4 0.1 0.4 0.0 2.6 0.8 0.0 0.2 0.4 1.4 1.3 0.9 1.7 1.3 3.1 1.6 2.0 1.6 1.2 2.5 1.8 3.0 0.0 2.0 2.3 2.9 3.3 1.4 3.5 6.2 5.7 6.0 4.3 1.5 1.5 5.8 3.7 2.1 6.1 3.9 3.6 1.9 0.6 0.0 3.4 3.2 5.1 6.7 11.1 2.4 1.4 6.8 3.4 2.0 2.1 9.5 3.5 8.6 1.3 2.6 1.7 3.3 6.7 4.1 1.0 2.1 0.4 3.1 2.2 5.4 1.9 1.1 1.3 5.2 3.0 4.5 1.3 6.3 3.4 0.7 2.3 0.6 1.3 5.7 2.8 0.0 2.5 2.6 0.1 0.5 9.8 6.3 3.3 3.1 4.3 5.7 5.7 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SRCAP "DOMO1, EAF1, KIAA0309, SWR1" ENSG00000080603 "Snf2 related CREBBP activator protein" Q6ZRS2 16 30698209-30741409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 186.4;Club cells: 145.6;Ionocytes: 179.0;Respiratory ciliated cells: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028929 Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA028929: AB_10601265" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (5.07e-1)" "unprognostic (6.57e-2)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (8.59e-2)" "unprognostic (2.34e-2)" "unprognostic (3.77e-1)" "unprognostic (6.45e-2)" "unprognostic (4.36e-2)" "unprognostic (8.57e-2)" "unprognostic (1.16e-2)" "unprognostic (2.09e-1)" "unprognostic (4.11e-2)" "unprognostic (7.71e-2)" "unprognostic (1.07e-1)" 15.4 11.9 3.6 18.9 4.8 30.1 10.1 7.1 4.2 12.8 1.7 13.2 15.7 15.5 6.4 13.5 14.2 10.9 12.1 2.9 3.4 9.6 7.1 11.6 15.3 5.9 4.3 16.9 19.4 20.2 9.5 12.6 3.5 12.6 11.2 12.5 18.0 13.1 24.5 16.2 16.1 15.0 0.8 18.7 16.0 20.6 7.7 20.2 14.0 19.4 13.6 11.3 9.9 6.8 29.5 60.1 36.9 35.9 28.3 19.5 37.7 24.0 21.1 26.2 20.7 27.8 21.9 65.9 29.7 30.5 16.9 27.8 37.7 27.5 21.9 42.2 88.1 42.5 56.2 24.3 11.4 49.8 48.0 20.8 13.2 40.3 29.0 12.8 27.8 21.7 65.4 36.5 19.7 34.5 42.2 17.4 37.6 10.8 27.7 57.7 28.7 36.4 7.5 34.2 34.5 36.5 26.6 31.0 8.4 12.2 35.4 26.0 44.1 37.0 26.5 21.0 31.6 39.8 36.7 45.9 29.7 23.2 28.9 0.3 0.7 2.9 0.8 1.2 0.6 0.7 0.4 0.9 0.5 1.0 0.5 0.4 2.2 0.6 0.3 0.9 0.9 0.7 3.6 4.8 7.1 4.2 2.9 3.4 5.9 4.3 3.5 0.8 7.7 6.8 3.0 3.2 3.7 8.8 9.8 24.6 1.9 186.4 13.1 7.5 3.3 1.8 2.4 4.3 145.6 1.8 8.4 2.3 5.3 54.3 0.0 1.4 1.2 4.6 3.0 3.4 11.3 7.6 8.6 3.1 1.4 4.2 19.9 4.7 2.5 3.0 2.2 3.0 2.3 8.4 8.6 17.7 179.0 1.9 14.3 0.9 2.8 3.4 10.6 8.4 3.0 1.7 6.2 4.5 10.6 1.9 39.1 1.2 11.1 3.1 3.1 0.6 118.3 5.8 0.0 5.0 14.3 5.6 6.0 7.8 58.2 2.5 8.9 2.0 25.6 3.1 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 379.9;Late spermatids: 599.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 61.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 8.7 6.0 6.4 18.1 8.2 41.7 14.5 10.0 14.8 12.5 6.8 31.2 25.2 12.7 9.3 23.9 8.6 11.9 8.3 8.9 3.7 16.7 16.0 12.9 19.7 4.0 4.1 8.7 23.3 14.5 9.0 14.5 4.3 9.6 35.6 25.8 16.1 10.9 20.0 26.7 23.6 14.2 2.4 17.8 18.0 44.7 5.2 19.9 8.7 12.6 24.3 31.0 16.2 11.6 104.1 39.2 54.9 82.4 30.2 39.3 69.0 62.1 60.1 57.3 60.2 109.0 34.1 139.0 51.8 39.1 65.5 51.3 110.3 74.2 100.6 96.2 79.9 73.5 42.6 93.8 26.7 111.3 34.0 25.6 39.3 66.0 84.7 44.6 72.3 76.4 157.7 55.6 48.2 36.8 111.1 80.8 45.9 62.9 42.7 77.8 67.3 84.1 56.8 169.5 117.5 42.9 65.4 59.3 42.5 55.2 33.3 70.3 54.8 52.4 41.3 37.2 78.6 33.1 78.6 128.5 20.9 124.3 48.1 61.0 4.4 30.6 8.5 5.3 12.1 8.6 11.2 11.5 5.9 6.9 9.2 10.0 50.9 11.2 7.6 3.3 14.9 6.3 6.4 8.2 10.0 14.8 8.9 3.7 4.0 4.1 4.3 2.4 5.2 11.6 26.6 9.6 25.8 18.6 40.0 42.3 119.3 91.0 67.7 36.8 25.8 22.7 28.7 14.3 51.4 22.0 37.5 54.3 33.1 51.6 29.4 55.4 379.9 29.9 40.2 29.2 46.2 46.7 74.2 68.2 53.2 25.1 46.9 54.0 7.6 44.1 13.2 41.8 21.6 10.1 50.0 50.8 32.6 16.3 19.9 599.1 22.1 20.0 16.0 24.4 31.5 16.8 32.0 30.2 29.7 100.4 47.9 24.8 68.0 117.9 50.8 59.4 33.8 92.9 6.6 17.8 48.9 197.3 100.4 126.8 41.8 39.7 43.6 33.7 90.7 162.6 SRSF10 "FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2" ENSG00000188529 "Serine and arginine rich splicing factor 10" O75494 1 23964347-23980927 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053805, HPA053831" Uncertain Supported Nucleoplasm NA Yes 49000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053805: AB_2682269, HPA053831: AB_2682275" "unprognostic (2.49e-1)" "unprognostic (3.10e-1)" "unprognostic (1.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.18e-6)" "unprognostic (2.05e-2)" "unprognostic (1.68e-3)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.74e-4)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.69e-2)" "unprognostic (1.59e-1)" "unprognostic (2.76e-1)" "unprognostic (2.40e-2)" 57.0 59.9 22.5 46.3 23.3 119.6 46.9 26.5 30.1 51.7 29.9 48.8 38.0 49.6 40.7 43.8 56.3 29.2 40.0 23.2 24.4 56.3 56.7 49.6 61.0 23.3 23.5 61.1 50.1 37.2 43.6 42.2 24.3 47.9 45.0 46.5 45.4 32.1 37.7 40.1 50.2 41.3 25.0 49.0 47.9 34.7 23.1 55.8 61.3 24.4 57.1 43.0 45.0 28.6 110.7 89.6 142.9 92.9 88.6 68.2 98.0 133.4 53.5 116.8 102.3 83.5 112.8 239.5 82.7 63.5 73.8 99.7 163.4 89.7 140.7 140.9 122.7 134.5 160.3 115.1 62.2 164.3 107.9 44.2 68.5 74.3 72.9 66.8 89.1 92.1 187.2 83.4 99.3 77.2 167.9 118.1 196.2 139.6 84.4 162.9 99.7 127.6 102.1 86.4 104.9 85.5 98.7 88.2 100.1 97.4 94.2 129.5 89.2 94.7 99.5 89.2 126.4 94.6 134.6 189.1 83.4 185.9 112.8 112.8 67.7 74.0 51.3 84.1 65.1 80.2 58.5 60.3 58.1 68.8 62.9 55.8 43.9 74.5 82.0 69.6 75.9 72.3 22.5 23.3 26.5 30.1 23.2 24.4 23.3 23.5 24.3 25.0 23.1 28.6 115.8 112.2 112.1 39.2 188.4 42.6 115.5 23.2 183.2 159.1 104.4 103.4 59.1 97.2 85.5 79.1 160.6 116.8 150.5 85.6 78.2 94.2 115.4 96.7 138.3 109.8 122.0 154.2 54.7 89.2 164.1 111.3 93.8 106.7 93.6 181.0 86.0 63.8 82.0 99.3 50.9 92.4 36.7 51.2 41.3 118.5 127.7 83.4 26.6 44.0 101.5 131.6 111.2 54.8 67.2 78.6 85.9 110.6 169.4 122.6 67.4 74.6 94.6 287.5 105.2 121.8 125.8 188.1 150.5 140.0 45.5 63.3 142.6 335.7 106.3 100.1 SRSF5 "HRS, SFRS5, SRP40" ENSG00000100650 "Serine and arginine rich splicing factor 5" Q13243 14 69726900-69772005 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043484, HPA056523" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 23000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "HPA043484: AB_10797143, HPA056523: AB_2683164" "unprognostic (2.08e-3)" "prognostic favorable (7.91e-4)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.30e-3)" "unprognostic (1.07e-3)" "unprognostic (2.37e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (1.00e-2)" 210.9 188.4 68.1 149.5 72.5 456.9 229.8 60.3 108.2 174.2 125.9 231.8 129.2 222.5 218.0 217.9 240.9 130.1 154.4 75.9 69.7 119.6 183.8 214.8 210.1 75.5 71.1 220.0 136.6 188.1 215.5 105.1 74.1 172.7 164.8 233.8 235.8 126.7 217.6 282.0 256.6 180.3 66.0 211.8 212.8 104.1 69.5 214.7 224.8 68.3 155.0 189.3 177.4 97.1 456.4 133.5 313.8 141.4 192.7 179.6 177.4 214.6 239.7 177.6 183.7 164.7 283.6 473.1 110.4 301.8 174.7 210.2 242.5 309.2 209.7 407.4 142.3 354.3 386.7 183.6 224.3 334.7 255.7 350.9 201.2 199.7 216.3 260.4 247.0 401.8 255.4 268.3 114.3 382.1 385.1 232.4 182.0 356.6 128.2 324.0 148.5 183.3 237.2 563.1 165.9 236.3 364.3 214.1 296.0 188.5 235.9 292.3 299.7 98.4 264.2 110.9 205.6 261.6 184.5 754.8 232.3 286.1 140.1 137.1 65.8 103.6 93.1 117.9 94.9 109.5 83.1 85.0 70.1 108.7 81.1 79.6 161.9 86.2 129.6 99.8 74.8 77.2 68.1 72.5 60.3 108.2 75.9 69.7 75.5 71.1 74.1 66.0 69.5 97.1 380.7 253.2 309.1 218.1 392.8 138.0 768.6 610.1 204.9 387.4 248.6 259.1 195.0 240.2 386.6 183.9 239.8 444.3 542.9 471.8 320.8 201.7 190.3 224.2 169.8 293.6 302.9 195.4 199.5 171.8 261.5 288.0 188.6 225.3 480.2 251.3 249.9 225.4 217.7 378.6 177.7 376.6 380.5 236.2 154.3 105.0 345.5 314.7 133.4 104.9 323.4 277.4 428.5 128.2 268.7 226.6 538.5 267.1 212.3 376.7 484.7 228.2 373.4 317.3 276.1 583.7 354.2 201.8 149.8 196.4 145.6 749.2 456.6 201.6 275.5 542.1 SRSF7 "9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2" ENSG00000115875 "Serine and arginine rich splicing factor 7" Q16629 2 38743599-38751494 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043850, HPA056926" Supported Enhanced Nucleoplasm NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA043850: AB_10964495, HPA056926: AB_2683277" "unprognostic (2.74e-1)" "unprognostic (1.53e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.86e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-5)" "unprognostic (3.24e-2)" "unprognostic (2.53e-2)" "unprognostic (2.61e-1)" "unprognostic (3.75e-1)" "unprognostic (4.44e-3)" "prognostic unfavorable (3.18e-8)" "unprognostic (1.02e-2)" "unprognostic (1.87e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-3)" 68.3 44.5 30.5 59.3 31.8 132.8 53.3 32.3 36.0 37.3 33.9 55.0 30.4 43.8 40.7 65.3 45.2 24.0 37.7 32.3 33.6 47.0 49.4 50.5 72.0 30.8 30.2 34.6 33.6 36.1 30.0 50.7 30.8 38.9 52.2 25.0 37.4 34.5 41.9 37.8 46.2 52.9 33.3 45.8 50.6 54.0 30.7 87.0 34.3 27.7 90.1 68.4 40.9 34.4 271.3 229.3 304.4 197.1 91.8 71.8 213.7 225.2 96.6 222.9 177.9 272.9 202.4 436.1 150.9 148.2 206.9 149.2 385.7 277.1 266.7 274.7 240.9 264.3 154.8 281.2 78.1 329.3 185.4 43.4 92.8 153.3 295.0 94.3 187.9 180.3 388.5 171.1 191.6 298.9 421.2 289.9 331.5 313.3 208.4 367.8 253.4 248.0 168.2 257.3 207.2 201.6 215.3 190.1 156.5 189.7 172.8 295.0 163.1 134.3 210.2 116.3 317.6 186.6 297.8 658.9 159.1 339.1 189.3 23.4 71.2 27.8 59.8 103.3 65.0 63.3 46.1 60.3 142.4 40.7 51.4 59.7 6.8 65.7 61.7 85.8 53.4 77.5 30.5 31.8 32.3 36.0 32.3 33.6 30.8 30.2 30.8 33.3 30.7 34.4 445.1 80.1 208.8 31.3 453.7 259.5 460.8 255.9 220.3 122.7 226.9 367.2 67.8 87.2 177.0 64.4 118.9 313.7 730.0 214.7 156.5 195.4 173.6 104.6 193.5 245.7 178.0 153.5 96.6 132.2 478.1 264.0 258.9 130.4 320.4 273.2 150.0 85.3 241.9 121.1 82.2 222.5 140.4 123.4 242.6 45.2 138.5 289.2 152.9 65.6 222.6 253.9 239.9 74.9 100.8 149.0 179.3 109.9 337.7 309.9 192.1 94.1 116.4 225.8 118.3 317.9 408.1 286.7 287.3 163.0 243.5 250.2 652.4 186.4 242.8 344.7 STAM STAM1 ENSG00000136738 "Signal transducing adaptor molecule" Q92783 10 17644151-17716824 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 76.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034399, HPA043882" Supported Supported Vesicles NA NA 82000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Vesicles "CAB034399: AB_2197486, HPA043882: AB_2678713" "unprognostic (1.09e-2)" "unprognostic (8.32e-2)" "unprognostic (1.10e-1)" "unprognostic (3.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.04e-1)" "prognostic unfavorable (3.44e-6)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (8.58e-2)" "unprognostic (1.37e-2)" "unprognostic (8.39e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" 10.8 13.3 7.7 6.9 9.7 53.1 8.9 14.0 11.8 10.7 3.4 8.0 8.2 9.0 5.8 12.2 7.8 9.1 18.0 9.2 8.7 10.2 6.9 10.9 7.5 9.8 9.5 11.4 10.4 10.3 7.4 8.5 9.8 8.7 7.7 11.2 8.5 6.1 24.5 10.0 7.3 8.5 9.6 6.8 11.4 8.1 9.1 13.1 10.8 10.1 7.5 10.9 9.0 14.7 34.8 19.8 30.8 14.2 30.1 21.9 10.3 45.1 19.8 41.0 33.1 25.9 31.7 9.1 7.2 33.9 31.7 18.2 27.6 21.1 35.0 10.9 12.7 86.3 15.3 43.1 31.8 6.5 43.7 22.7 27.0 33.6 28.3 26.6 19.8 56.3 30.1 10.5 43.8 10.4 35.7 5.6 14.7 19.7 10.2 18.0 29.0 11.9 17.5 11.2 13.0 19.2 24.6 16.7 34.6 24.1 27.5 9.4 26.6 23.9 24.5 42.7 21.1 6.6 11.5 15.6 25.6 9.6 15.6 47.5 7.5 12.5 5.9 8.2 5.6 5.4 12.8 6.2 9.6 3.1 8.8 7.1 5.9 17.3 7.5 5.5 76.5 6.4 7.7 9.7 14.0 11.8 9.2 8.7 9.8 9.5 9.8 9.6 9.1 14.7 13.2 12.8 23.4 15.7 14.1 22.9 5.3 16.2 23.9 19.7 9.4 8.9 30.0 5.7 14.0 16.5 10.4 10.2 24.3 6.4 5.9 15.1 3.5 16.3 22.3 11.0 11.4 56.8 31.7 13.4 10.5 23.5 15.8 25.9 31.6 13.0 10.4 7.8 15.5 10.1 36.9 7.8 2.0 10.4 16.3 3.5 9.6 15.6 19.6 39.4 8.4 13.7 10.3 31.7 59.4 29.9 8.0 6.0 20.8 10.1 5.7 15.6 14.0 14.5 26.3 22.3 12.6 22.1 14.6 21.8 21.0 24.6 27.6 18.4 8.1 8.5 STRIP1 "FAM40A, FAR11A, FLJ14743, KIAA1761" ENSG00000143093 "Striatin interacting protein 1" Q5VSL9 1 110031577-110074641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060302, HPA060498" Approved Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA060302: AB_2684247, HPA060498: AB_2684293" "unprognostic (2.75e-2)" "unprognostic (3.91e-1)" "unprognostic (2.81e-2)" "unprognostic (1.63e-1)" "unprognostic (5.09e-1)" "unprognostic (2.90e-2)" "unprognostic (1.01e-2)" "unprognostic (9.08e-2)" "unprognostic (2.83e-1)" "unprognostic (6.29e-2)" "unprognostic (1.41e-3)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (1.82e-1)" "unprognostic (6.23e-2)" "unprognostic (2.23e-2)" 14.9 14.9 13.0 11.7 13.9 22.6 13.9 9.9 14.3 19.2 8.8 16.1 13.1 19.1 15.6 15.2 15.6 10.8 12.7 14.5 13.4 12.3 9.8 12.7 15.6 11.9 12.9 21.5 12.6 21.3 15.7 16.6 14.0 12.9 13.4 11.9 14.1 13.8 14.1 17.5 19.7 18.0 10.1 22.6 13.5 19.4 17.2 16.2 13.6 13.7 15.4 15.4 14.9 12.0 19.7 12.8 34.3 23.4 29.3 19.3 24.7 30.3 26.3 30.9 26.8 13.5 11.2 16.0 16.2 27.0 19.6 18.3 18.4 21.5 21.7 34.2 22.3 26.7 23.1 17.7 16.2 24.3 25.6 20.7 25.3 26.2 28.6 22.7 25.0 21.6 24.1 19.9 30.3 23.3 28.0 25.5 27.9 14.8 17.2 27.0 44.1 14.3 21.4 28.5 44.1 25.4 25.9 32.4 19.5 19.7 16.2 21.9 25.9 23.2 22.1 27.2 20.5 20.3 12.0 16.3 26.5 25.9 34.2 13.9 10.5 14.8 14.9 11.4 13.0 10.7 12.5 15.7 12.2 10.2 14.4 13.0 9.6 16.1 15.5 5.6 12.6 12.8 13.0 13.9 9.9 14.3 14.5 13.4 11.9 12.9 14.0 10.1 17.2 12.0 9.0 3.2 7.8 17.3 16.4 13.8 10.0 7.2 9.6 12.6 8.3 5.7 8.5 4.3 8.2 9.2 18.8 16.1 11.9 15.5 1.9 10.7 47.3 9.1 9.6 13.2 15.0 13.0 15.6 7.2 10.4 10.6 11.7 15.1 7.0 16.2 14.6 9.8 12.9 6.7 17.7 13.0 8.2 11.1 11.6 58.0 9.9 8.9 3.6 7.5 14.3 7.1 17.5 15.1 12.6 12.5 10.2 10.1 11.9 11.5 23.1 3.9 3.0 18.9 6.6 11.4 12.5 11.3 10.2 10.9 12.8 25.9 15.2 13.0 11.5 14.1 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SUSD6 KIAA0247 ENSG00000100647 "Sushi domain containing 6" Q92537 14 69611596-69715144 "Predicted membrane proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030464 Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Intermediate filaments" "HPA030464: AB_10601128" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (7.34e-2)" "unprognostic (1.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.46e-2)" "unprognostic (2.17e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-1)" "unprognostic (3.66e-3)" "unprognostic (1.10e-2)" "unprognostic (6.70e-2)" "prognostic favorable (2.16e-4)" "unprognostic (1.10e-2)" "unprognostic (5.35e-2)" "unprognostic (1.30e-2)" "unprognostic (2.34e-1)" 25.3 19.3 12.0 32.9 12.4 67.2 22.2 26.7 11.6 16.2 13.1 20.9 25.4 13.0 43.1 31.8 21.0 27.5 15.6 13.5 12.8 22.2 12.2 37.1 30.4 24.5 14.5 13.5 22.1 16.6 14.4 17.0 15.3 17.8 19.0 15.6 29.7 16.7 12.3 27.3 32.8 19.7 18.2 33.6 20.9 10.7 14.2 21.7 22.4 11.5 36.2 21.7 18.1 15.5 19.4 4.9 7.0 6.4 14.0 10.2 12.8 10.7 22.6 6.0 5.8 5.9 16.7 22.6 11.8 13.5 4.8 26.4 4.0 22.1 5.6 38.9 3.0 18.4 4.1 9.8 22.6 3.0 45.6 16.6 21.5 10.1 18.7 6.5 12.4 6.9 5.7 19.6 8.4 9.5 4.5 8.1 1.4 11.3 5.0 7.7 6.2 9.1 11.5 9.8 3.0 4.7 8.8 25.4 4.0 5.1 10.4 8.3 19.4 13.8 8.1 8.8 4.4 13.5 3.2 15.7 8.9 10.3 7.4 16.3 11.6 12.3 5.5 10.2 5.5 5.3 4.8 3.4 7.6 5.0 4.6 3.4 33.0 4.1 13.7 4.3 4.6 8.8 12.0 12.4 26.7 11.6 13.5 12.8 24.5 14.5 15.3 18.2 14.2 15.5 45.6 12.8 30.0 22.2 24.6 0.0 36.0 0.0 23.3 16.7 44.2 21.5 14.0 21.5 11.2 18.4 20.9 4.3 32.9 44.3 7.9 26.7 1.0 34.7 13.3 32.8 7.3 13.9 34.6 24.6 1.7 13.1 18.8 28.4 8.8 9.7 17.9 15.9 23.5 15.2 21.1 21.9 0.0 67.4 0.0 5.1 5.3 44.3 0.0 107.7 31.6 4.3 16.5 22.1 28.4 38.7 20.4 6.8 15.1 43.0 74.1 15.2 10.9 23.7 26.3 18.3 19.0 8.4 15.4 19.7 0.0 9.2 21.2 7.6 8.5 54.6 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.92e-2)" "prognostic favorable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 4.0 2.2 4.7 4.2 4.4 13.7 3.5 4.9 5.1 2.9 2.0 3.4 3.1 3.2 12.5 5.0 3.3 1.7 3.6 4.3 5.1 2.6 6.6 2.7 7.5 5.2 5.6 3.8 2.9 2.3 3.0 3.3 4.8 3.0 3.2 3.3 2.6 3.0 4.9 4.4 4.2 2.6 3.9 6.0 3.6 4.9 5.0 9.7 2.6 3.8 7.0 3.4 2.4 4.3 28.7 34.3 13.3 14.0 3.4 4.0 27.0 13.5 10.2 25.8 21.0 21.0 18.7 31.4 8.0 9.9 26.1 19.8 33.0 19.3 15.4 24.2 33.8 12.3 31.8 17.4 2.0 30.7 6.6 3.6 3.7 22.8 11.6 4.2 18.6 20.2 31.9 21.6 14.2 33.1 26.8 32.0 15.7 14.0 32.8 19.3 24.5 33.1 8.6 15.7 17.4 11.4 18.3 17.4 9.8 14.8 26.0 25.5 10.0 15.8 27.0 22.1 23.3 14.6 23.9 26.4 11.8 43.6 17.7 4.9 2.8 6.8 8.5 4.0 6.2 4.6 5.5 9.1 2.2 5.4 6.8 6.6 2.0 10.6 6.5 2.6 11.0 6.5 4.7 4.4 4.9 5.1 4.3 5.1 5.2 5.6 4.8 3.9 5.0 4.3 1.2 6.4 0.0 0.3 3.5 1.8 0.9 2.0 2.8 5.3 2.2 2.5 2.5 2.8 1.3 1.8 0.0 6.5 6.6 2.1 3.9 2.9 0.2 1.3 0.9 1.7 3.0 6.9 0.7 2.9 28.3 1.9 3.1 1.0 1.3 2.9 1.8 6.7 5.2 0.0 1.0 2.6 0.0 2.9 1.6 0.2 1.2 2.4 5.4 1.0 3.0 0.9 6.2 1.0 0.8 2.3 1.7 1.5 7.1 0.6 1.6 2.4 2.6 3.8 0.0 1.8 2.5 3.7 0.8 2.5 1.1 6.2 3.6 1.7 3.2 0.6 SYF2 "CBPIN, DKFZp564O2082, fSAP29, NTC31, p29" ENSG00000117614 "SYF2 pre-mRNA splicing factor" O95926 1 25222276-25232502 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018265, HPA070710" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA018265: AB_10962002, HPA070710: AB_2686301" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (9.98e-2)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (6.76e-3)" "unprognostic (7.40e-3)" "unprognostic (2.36e-2)" "unprognostic (3.26e-1)" "unprognostic (1.33e-2)" "unprognostic (7.58e-2)" "unprognostic (4.89e-2)" "unprognostic (2.27e-2)" "unprognostic (4.80e-2)" "unprognostic (1.45e-3)" "prognostic favorable (5.72e-4)" 75.3 56.5 37.8 42.6 38.4 147.6 66.9 39.9 48.4 70.1 39.0 71.6 55.4 59.9 72.2 49.3 63.7 40.7 50.0 36.9 41.6 64.0 48.3 46.4 63.8 39.3 38.4 104.5 59.1 67.8 35.3 57.1 40.3 50.3 59.4 29.5 52.0 51.3 89.1 58.5 57.7 47.0 39.2 55.9 61.9 26.9 38.4 77.6 59.0 57.8 76.8 63.2 60.1 41.4 54.0 22.0 54.9 45.4 85.2 109.0 42.4 56.1 91.0 52.7 47.8 13.7 73.0 46.2 75.6 68.1 39.8 47.3 47.6 43.2 76.4 76.2 39.4 52.8 56.1 41.8 86.6 75.9 54.3 79.4 118.2 54.3 75.2 100.4 76.0 61.8 42.0 74.4 75.2 19.8 77.6 104.0 71.7 78.9 32.4 51.3 46.3 78.9 86.9 28.6 47.8 69.5 49.1 44.5 160.5 47.7 38.3 91.5 61.8 45.9 40.6 87.0 46.8 86.7 83.4 48.6 67.6 77.7 45.2 185.5 82.1 222.9 79.1 98.4 95.7 140.0 102.4 99.9 70.0 125.5 108.4 102.0 337.6 111.3 121.6 67.3 129.2 92.7 37.8 38.4 39.9 48.4 36.9 41.6 39.3 38.4 40.3 39.2 38.4 41.4 160.7 128.2 112.8 6.8 176.0 159.3 123.0 238.5 111.5 74.3 134.9 174.1 108.1 147.3 151.3 189.4 83.4 195.7 203.9 211.7 246.5 158.6 78.7 153.2 125.9 137.4 111.4 117.6 10.6 174.2 130.1 121.1 59.1 166.8 232.4 120.9 154.9 131.3 126.4 58.9 10.2 166.0 181.0 231.5 155.4 32.1 214.6 155.4 108.5 3.7 251.8 95.0 217.3 6.0 12.5 154.5 221.1 164.7 83.0 109.5 322.0 273.4 151.0 90.5 164.3 139.5 142.5 98.2 108.8 88.1 171.3 280.6 176.8 95.9 171.8 147.2 TAF11 "TAF2I, TAFII28" ENSG00000064995 "TATA-box binding protein associated factor 11" Q15544 6 34877462-34888071 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029326, HPA049127" Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Golgi apparatus" "HPA029326: AB_2672999, HPA049127: AB_2680645" "unprognostic (4.02e-2)" "unprognostic (5.36e-3)" "unprognostic (7.41e-2)" "unprognostic (5.18e-3)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (2.56e-3)" "unprognostic (1.45e-2)" "unprognostic (1.68e-3)" "prognostic favorable (5.87e-4)" "unprognostic (2.91e-1)" "unprognostic (6.77e-3)" "unprognostic (1.89e-2)" "unprognostic (3.24e-1)" "unprognostic (1.87e-2)" "unprognostic (4.92e-1)" "unprognostic (3.32e-1)" 23.2 27.9 21.3 19.5 22.4 47.1 23.0 24.8 26.5 23.9 22.0 27.8 19.3 22.6 18.4 25.8 25.1 15.5 29.5 21.4 21.0 27.5 28.5 25.5 27.1 22.0 21.7 27.9 27.2 16.7 19.8 22.6 22.0 26.2 20.6 24.8 20.9 16.9 32.6 29.0 26.5 20.7 21.1 33.8 25.1 33.4 22.3 23.7 24.4 21.6 25.4 24.9 23.1 25.6 37.2 15.4 50.2 91.4 29.5 30.8 44.5 29.5 23.1 47.2 44.8 35.9 23.0 49.5 37.8 27.3 23.1 23.4 61.5 25.1 37.7 30.3 49.6 55.7 30.7 58.8 41.3 74.9 38.6 35.8 41.2 32.2 25.2 28.8 57.6 55.0 89.0 38.1 22.6 65.6 48.1 63.4 45.9 74.3 26.0 51.6 44.9 39.7 34.4 23.0 60.6 55.3 33.9 37.9 68.6 41.5 59.4 88.6 34.6 33.3 44.6 20.1 36.9 35.2 90.5 72.4 12.2 86.3 49.9 43.6 27.8 24.5 14.3 25.8 13.8 13.8 14.9 15.4 24.1 17.1 17.4 15.6 17.5 17.6 21.7 21.5 21.4 15.9 21.3 22.4 24.8 26.5 21.4 21.0 22.0 21.7 22.0 21.1 22.3 25.6 49.9 28.9 19.5 18.3 44.9 46.0 31.4 36.1 24.5 29.0 55.1 44.3 24.0 25.8 31.3 42.3 12.5 71.9 50.4 33.5 64.6 47.9 6.6 37.4 49.7 43.8 39.5 39.5 20.8 63.2 68.9 33.5 29.6 47.7 22.2 57.8 61.1 58.8 44.2 32.0 23.7 38.4 50.8 52.2 32.2 10.6 33.8 36.5 24.9 13.1 48.5 37.8 48.4 16.6 33.6 50.8 51.2 37.2 44.0 32.9 43.5 48.9 17.1 32.9 32.9 34.0 35.5 130.9 71.2 36.3 58.4 76.8 44.3 38.2 40.6 31.2 TALDO1 ENSG00000177156 "Transaldolase 1" P37837 11 747415-765012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pentose shunt" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 820.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 2870.4;neutrophil: 3726.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048089 Approved Nucleoplasm,Cytosol NA NA 29000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA048089: AB_2680260" "unprognostic (5.29e-2)" "unprognostic (1.78e-2)" "unprognostic (3.47e-1)" "unprognostic (9.65e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.78e-2)" "unprognostic (4.27e-2)" "unprognostic (1.74e-1)" "unprognostic (7.97e-3)" "unprognostic (2.94e-1)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.16e-3)" 139.5 80.7 108.0 121.8 128.8 464.8 121.0 129.3 119.3 101.9 105.2 99.6 116.0 68.4 66.4 330.6 79.1 100.0 95.5 108.0 113.8 111.6 136.2 109.1 107.8 135.8 119.3 77.0 107.5 49.3 53.0 88.0 130.0 91.9 78.4 34.2 132.8 60.1 120.7 132.7 101.0 60.8 124.0 152.6 132.5 40.4 120.1 109.9 140.3 107.1 115.8 160.8 142.1 148.2 331.0 405.5 115.4 218.1 235.8 136.5 338.0 242.2 313.8 238.2 194.5 176.6 694.8 179.5 323.1 324.7 181.9 345.5 185.6 263.5 122.8 238.9 372.5 310.9 146.0 616.4 250.3 498.4 449.0 112.0 210.6 159.6 129.0 170.4 331.6 224.0 413.5 294.3 224.5 318.0 296.4 601.2 183.9 478.9 326.0 243.5 131.5 656.4 437.9 185.4 284.2 100.1 224.9 466.1 243.3 102.4 220.0 383.9 434.1 107.9 99.5 86.0 232.9 122.9 132.1 223.5 238.5 440.5 444.7 1456.7 1203.5 2870.4 94.1 432.7 102.3 145.5 125.7 115.5 654.2 127.2 100.9 94.9 3726.6 112.2 457.8 267.0 192.7 1066.0 108.0 128.8 129.3 119.3 108.0 113.8 135.8 119.3 130.0 124.0 120.1 148.2 90.2 141.1 117.2 10.7 91.1 73.5 199.8 354.0 61.5 50.3 113.0 122.2 46.4 100.1 253.4 150.8 14.6 419.8 83.8 151.0 250.5 230.4 82.1 156.5 85.4 85.6 101.5 507.0 13.1 272.1 427.6 97.3 144.3 216.7 161.4 86.0 93.5 149.7 418.3 50.5 11.6 186.0 268.5 271.8 169.4 21.2 117.8 352.8 140.5 7.5 820.0 142.1 84.5 10.6 54.8 257.6 200.3 104.2 129.4 361.9 197.7 309.1 232.6 61.7 72.3 59.6 115.0 143.2 140.6 257.6 83.1 526.6 86.8 77.5 215.1 342.6 TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA027908: AB_10602073, HPA027909: AB_10601857, HPA027910: AB_10602203" "unprognostic (9.83e-2)" "unprognostic (5.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (8.15e-5)" "unprognostic (2.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (9.48e-2)" "unprognostic (6.06e-3)" "unprognostic (3.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.53e-3)" "unprognostic (9.87e-2)" "unprognostic (2.71e-1)" "unprognostic (3.19e-1)" "unprognostic (9.73e-2)" 5.8 12.1 8.3 5.1 8.4 18.3 5.7 8.3 8.2 7.9 8.8 6.5 7.9 6.4 7.4 14.1 8.2 5.9 7.4 8.3 8.0 8.6 6.1 8.0 5.8 7.7 8.1 9.4 12.8 10.7 6.7 6.0 7.9 8.2 7.7 7.7 11.8 5.5 15.0 15.2 8.5 6.7 7.1 7.2 7.5 10.0 8.5 13.5 7.7 7.8 7.1 7.5 9.3 8.1 13.2 5.5 9.9 10.9 9.1 9.1 14.2 7.2 15.0 13.2 16.2 12.6 8.5 12.3 7.4 9.2 17.9 8.9 12.7 11.6 14.8 19.9 10.4 19.5 9.0 17.2 13.0 11.1 15.9 7.8 16.6 13.0 15.4 12.6 18.9 20.4 22.5 3.1 9.6 11.9 16.6 8.4 13.0 15.0 5.1 10.7 9.1 9.6 13.6 9.5 13.0 8.4 7.9 11.2 14.3 13.3 8.2 19.7 18.4 8.0 12.2 5.5 9.6 11.1 12.4 80.8 5.5 16.5 12.6 1.4 2.6 4.4 2.3 3.5 2.7 1.7 2.6 2.3 4.0 2.0 2.8 2.4 1.1 3.0 1.5 1.1 1.9 2.6 8.3 8.4 8.3 8.2 8.3 8.0 7.7 8.1 7.9 7.1 8.5 8.1 4.1 3.2 5.6 17.9 6.3 8.2 8.5 7.5 8.0 5.0 6.0 3.7 5.8 7.2 10.1 1.8 4.2 6.3 4.6 15.1 3.9 12.3 5.6 10.6 3.6 4.9 1.8 10.5 20.3 15.4 9.2 4.2 3.1 8.1 5.7 5.0 3.6 3.9 5.8 0.0 22.0 4.9 10.2 4.4 7.8 5.0 3.1 4.1 1.8 6.5 6.0 3.6 6.2 14.1 24.1 15.0 6.8 1.2 5.6 10.0 11.2 9.0 15.8 4.5 0.0 4.2 3.6 6.5 6.4 10.8 15.9 6.7 6.6 3.2 6.3 11.2 TCERG1 "CA150, TAF2S, Urn1" ENSG00000113649 "Transcription elongation regulator 1" O14776 5 146447311-146511961 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064854, HPA069752, HPA069808" Supported Enhanced Nucleoplasm NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA064854: AB_2685370, HPA069752: AB_2686190, HPA069808: AB_2686204" "unprognostic (2.73e-1)" "unprognostic (5.11e-2)" "unprognostic (1.27e-3)" "unprognostic (8.58e-2)" "unprognostic (1.32e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (1.07e-1)" "unprognostic (3.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.35e-3)" "prognostic unfavorable (4.70e-11)" "unprognostic (1.52e-2)" "unprognostic (7.76e-2)" "unprognostic (3.98e-2)" "unprognostic (1.24e-3)" 11.6 8.6 6.6 15.5 6.1 28.1 12.0 7.9 10.0 11.6 4.1 12.2 10.5 13.3 6.4 13.1 12.5 7.3 10.0 6.4 5.2 9.2 6.7 10.5 17.7 5.5 5.1 13.7 9.0 8.9 11.3 12.4 5.5 10.4 10.8 16.9 10.9 8.4 23.7 13.2 11.2 10.4 4.2 12.0 11.7 10.3 5.3 19.0 10.0 13.6 17.1 12.4 12.3 8.8 51.7 37.6 56.6 39.1 15.2 23.9 72.0 38.0 30.6 42.1 48.8 61.0 53.8 89.0 27.8 31.7 30.0 44.6 70.1 48.1 63.8 52.6 56.3 58.1 43.4 37.4 16.3 87.8 43.5 16.8 28.0 40.8 43.7 23.0 37.3 73.5 69.4 31.9 32.2 36.8 76.8 49.3 56.3 29.2 42.3 74.3 66.9 58.7 26.3 40.2 36.8 45.6 42.7 44.6 28.3 34.1 47.5 43.9 42.2 36.3 42.1 31.0 60.2 32.4 38.3 116.8 33.7 73.0 41.3 0.9 5.7 2.5 5.7 8.8 6.9 5.5 6.6 7.2 9.7 5.5 6.8 6.8 0.5 9.5 11.9 4.9 6.5 5.3 6.6 6.1 7.9 10.0 6.4 5.2 5.5 5.1 5.5 4.2 5.3 8.8 35.8 54.5 49.8 50.6 49.5 44.9 49.5 35.6 54.7 54.1 32.4 33.1 35.6 14.3 39.9 23.9 62.6 48.6 42.9 20.8 1.9 31.9 3.2 23.8 62.1 37.6 28.2 77.0 100.9 33.4 60.7 43.3 56.6 44.1 37.9 57.4 21.4 17.6 30.8 35.3 91.0 36.9 24.4 28.9 30.4 7.4 28.6 36.5 24.9 42.2 33.1 20.8 35.0 73.4 76.3 44.9 25.3 24.5 61.9 60.7 13.8 7.6 33.8 38.4 19.7 53.2 51.1 73.3 60.8 66.6 45.7 43.9 42.8 43.7 47.5 62.2 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 13.9;Glandular and luminal cells: 25.1;granulocytes: 19.6;Plasma cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 20.7;eosinophil: 13.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "HEL: 13.5;HMC-1: 20.3;U-266/70: 20.3;U-266/84: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 0.9 1.7 0.1 2.1 0.2 6.1 1.4 0.1 0.4 1.2 1.0 1.3 1.6 1.1 4.2 3.4 1.9 1.1 1.3 0.0 0.4 1.1 2.5 2.0 3.1 1.1 0.3 0.4 0.8 1.2 0.6 1.1 1.1 0.5 1.3 1.8 2.3 1.0 0.6 3.6 1.5 0.8 0.3 1.7 1.1 1.2 0.7 2.0 1.3 0.5 3.3 1.0 1.6 0.2 3.0 0.8 0.0 0.0 0.0 0.0 0.1 0.5 2.2 1.3 2.7 0.0 2.2 1.9 2.0 0.0 0.1 0.6 1.1 0.0 1.8 0.1 0.8 13.5 1.0 0.1 0.0 2.2 20.3 0.0 0.3 1.7 0.0 1.4 0.0 0.6 7.5 0.5 4.1 1.0 1.3 4.9 0.4 1.4 0.8 3.1 2.7 0.0 3.4 0.9 0.0 0.2 0.6 0.3 0.5 1.1 0.7 4.2 0.0 0.0 0.0 2.8 0.0 20.3 15.4 2.6 0.0 3.0 0.1 20.7 0.6 13.3 0.1 0.7 0.3 1.0 0.2 0.5 1.5 0.7 0.5 0.5 0.5 3.6 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.0 0.4 1.1 0.3 1.1 0.3 0.7 0.2 0.6 6.4 6.8 0.7 6.8 2.5 1.7 0.2 2.8 0.9 1.7 1.1 1.8 7.2 2.6 0.0 0.0 1.5 3.3 2.1 0.0 1.7 6.4 13.9 1.5 1.2 3.0 12.6 6.7 1.1 0.1 0.8 0.0 25.1 19.6 0.7 0.0 2.9 4.9 0.0 1.6 1.4 4.1 4.6 1.8 2.6 0.0 5.9 1.8 10.3 1.7 6.6 0.0 0.5 0.2 1.0 0.6 0.4 15.4 1.3 3.0 2.0 0.2 3.1 6.6 1.8 0.8 0.7 1.4 9.8 3.0 0.8 3.4 0.3 2.1 1.6 TEDC2 "C16orf59, FLJ13909" ENSG00000162062 "Tubulin epsilon and delta complex 2" Q7L2K0 16 2460086-2464963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;testis: 5.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.8;Extravillous trophoblasts: 12.5;Granulosa cells: 6.7;Hofbauer cells: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051394, HPA055389" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" "HPA051394: AB_2681465, HPA055389: AB_2732595" "unprognostic (3.23e-1)" "unprognostic (1.03e-2)" "unprognostic (2.14e-2)" "unprognostic (7.46e-3)" "unprognostic (1.27e-1)" "unprognostic (1.38e-3)" "prognostic unfavorable (2.43e-5)" "prognostic unfavorable (7.58e-4)" "unprognostic (4.04e-3)" "unprognostic (8.85e-2)" "unprognostic (3.74e-2)" "unprognostic (3.72e-2)" "unprognostic (1.16e-4)" "unprognostic (1.28e-3)" "unprognostic (1.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.03e-1)" 0.3 0.8 0.8 1.7 0.9 4.0 0.4 0.4 1.4 0.7 0.2 1.0 1.5 0.4 0.0 2.3 0.3 0.1 0.8 0.8 0.6 0.6 0.8 0.5 2.2 0.7 0.6 0.4 0.6 0.2 0.8 0.9 0.8 0.6 0.7 0.2 0.6 0.2 0.3 0.9 1.4 0.3 0.4 1.2 0.8 5.0 0.9 2.2 0.4 0.0 1.4 0.4 0.8 0.6 10.2 31.3 17.7 20.8 0.3 1.2 17.7 7.9 4.7 12.5 12.1 21.9 8.2 14.0 12.6 3.4 6.8 15.3 12.9 8.0 3.0 15.6 17.4 12.7 23.2 22.9 0.4 12.3 16.3 1.1 1.0 11.0 3.0 1.0 5.8 22.8 21.9 5.2 4.4 19.7 21.6 23.2 39.2 9.7 11.5 52.0 15.1 31.3 2.7 4.4 16.6 27.2 9.1 9.5 7.1 4.7 14.0 14.2 2.2 13.2 19.2 12.8 18.2 11.4 20.1 28.3 6.7 12.3 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.2 0.4 0.1 0.8 0.9 0.4 1.4 0.8 0.6 0.7 0.6 0.8 0.4 0.9 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 0.0 0.0 0.0 0.0 0.0 12.8 0.5 0.0 1.9 2.9 0.0 1.2 1.1 0.6 0.0 0.0 0.0 1.3 12.5 1.7 0.0 1.0 0.0 6.7 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.9 0.4 2.7 0.0 0.0 TENT2 "FLJ38499, GLD2, PAPD4, TUT2" ENSG00000164329 "Terminal nucleotidyltransferase 2" Q6PIY7 5 79612120-79686648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 37.6;Glandular and luminal cells: 33.2;Granulosa cells: 31.9;Hofbauer cells: 33.9;Syncytiotrophoblasts: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA054468: AB_2682497" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (8.03e-2)" "unprognostic (2.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.10e-1)" "unprognostic (6.80e-2)" "unprognostic (1.57e-3)" "unprognostic (9.37e-2)" "unprognostic (2.21e-1)" "unprognostic (7.71e-2)" "unprognostic (2.38e-1)" "unprognostic (8.43e-3)" "unprognostic (5.84e-3)" "unprognostic (2.67e-3)" 19.1 15.1 10.4 20.4 12.8 44.4 25.0 11.5 15.6 17.9 15.0 18.5 17.8 19.6 23.6 16.5 16.0 17.3 14.5 9.6 10.8 17.6 23.8 17.9 30.2 12.0 11.1 22.7 15.2 15.5 11.5 21.0 12.5 15.7 20.8 14.3 15.1 15.3 16.2 23.8 19.1 18.3 10.9 27.8 17.7 17.5 11.2 27.2 22.4 14.3 28.1 19.1 15.9 15.2 22.5 15.3 16.8 26.7 28.8 33.2 26.8 26.6 40.6 30.5 48.3 13.8 26.1 41.8 13.6 29.6 35.9 21.1 21.8 29.6 34.6 31.3 19.9 23.9 19.4 21.6 37.3 35.7 31.6 29.5 31.4 21.6 40.1 29.7 26.2 30.0 27.7 30.0 34.0 12.3 40.8 45.6 15.6 17.0 10.8 36.2 16.8 47.2 29.4 31.8 11.0 20.1 21.1 22.8 42.8 26.4 19.6 55.6 24.2 16.4 11.1 16.0 29.9 31.3 27.8 40.7 28.9 36.8 23.4 30.7 21.5 21.6 19.0 24.8 31.3 21.6 20.5 21.0 21.9 17.2 19.5 20.6 19.2 21.8 26.0 12.0 23.4 19.0 10.4 12.8 11.5 15.6 9.6 10.8 12.0 11.1 12.5 10.9 11.2 15.2 25.9 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 24.2 16.5 0.0 0.0 0.0 27.6 0.0 26.3 37.6 0.0 17.6 10.2 0.0 21.3 29.0 7.2 0.0 0.0 0.0 10.2 22.6 8.7 0.0 33.2 0.0 31.9 0.0 0.0 33.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 9.8 0.0 0.0 0.0 0.0 14.9 0.0 0.0 11.5 0.0 0.0 26.5 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 33.7 11.0 23.7 0.0 0.0 TENT4A "LAK-1, PAPD7, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Terminal nucleotidyltransferase 4A" Q5XG87 5 6713432-6757044 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Breast glandular cells: 13.4;Breast myoepithelial cells: 13.2;dendritic cells: 12.3;Endometrial stromal cells: 15.4;Glandular and luminal cells: 14.0;Granulosa cells: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: AB_2679346, HPA046742: AB_2679781" "unprognostic (1.45e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-2)" "unprognostic (2.12e-3)" "unprognostic (7.57e-2)" "unprognostic (1.30e-2)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.62e-1)" "unprognostic (9.78e-2)" "unprognostic (3.10e-3)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.99e-5)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.60e-2)" "prognostic favorable (8.55e-4)" 13.1 8.1 8.4 9.5 8.6 27.6 11.0 16.6 10.1 12.5 5.7 10.0 8.7 11.1 6.4 10.7 11.5 10.0 8.5 8.7 8.1 9.6 20.5 12.8 13.0 6.5 6.5 15.6 12.0 10.0 11.1 9.1 7.0 11.1 7.2 12.5 8.2 8.8 9.3 15.7 12.4 12.2 6.0 13.7 9.6 10.1 7.9 14.6 10.2 12.1 10.4 10.1 11.8 8.9 31.7 20.9 25.4 31.6 17.7 15.6 37.0 21.0 25.7 25.1 28.2 21.9 17.3 23.1 16.1 25.5 28.5 22.9 20.7 16.4 23.1 26.1 14.0 12.0 72.5 12.4 11.0 18.0 17.3 10.7 13.8 28.7 18.4 18.6 15.0 16.9 16.3 29.8 20.8 17.6 24.4 25.3 13.6 9.7 16.6 21.8 21.2 6.0 10.5 17.5 25.1 19.3 50.7 24.1 14.5 13.4 14.5 9.9 13.6 30.6 32.7 27.2 29.8 28.6 12.6 20.4 19.6 16.4 19.2 0.0 0.2 0.2 0.6 0.1 0.6 0.5 0.4 0.4 0.3 0.4 0.5 0.5 0.1 0.1 0.2 1.1 0.6 0.2 8.4 8.6 16.6 10.1 8.7 8.1 6.5 6.5 7.0 6.0 7.9 8.9 19.3 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 13.4 13.2 0.0 0.0 0.0 5.5 0.0 5.3 12.3 0.0 1.9 4.9 0.0 10.7 15.4 4.8 0.0 0.0 0.0 4.4 4.0 4.0 0.0 14.0 0.0 14.5 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 4.2 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 5.6 4.8 10.7 0.0 0.0 TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 89.1" "Cell type enhanced" "Detected in some" "B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 29.3" "Group enriched" "Detected in many" 17 "B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7" "Cell line enhanced" "Detected in many" "Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA054049: AB_2682356" "unprognostic (3.76e-2)" "unprognostic (3.85e-3)" "unprognostic (3.24e-3)" "prognostic favorable (3.75e-5)" "unprognostic (1.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.29e-1)" "unprognostic (2.88e-2)" "unprognostic (5.75e-2)" "unprognostic (1.36e-3)" "unprognostic (9.41e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.77e-5)" "unprognostic (6.26e-2)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-2)" 2.8 2.4 0.9 17.0 1.0 89.1 11.6 1.1 1.6 10.9 27.4 23.8 16.0 3.2 19.1 3.6 4.8 7.8 6.9 1.4 0.9 7.5 10.3 10.5 18.8 1.6 1.6 9.0 46.8 11.2 2.6 3.8 1.1 6.6 24.8 0.1 25.8 4.1 29.4 1.2 13.0 2.9 1.9 21.7 30.2 43.5 1.0 6.2 14.3 10.9 37.3 14.1 1.9 1.3 0.2 0.1 0.1 1.3 0.1 0.0 1.3 0.6 26.9 0.5 0.2 1.7 0.2 4.9 0.3 0.8 0.3 0.3 0.1 0.5 0.2 17.6 1.6 37.9 0.2 0.0 0.1 22.4 46.8 0.0 0.1 0.4 0.0 0.1 0.1 10.0 5.2 296.2 0.0 3.8 0.1 22.8 3.8 4.5 2.4 0.1 0.1 185.5 0.3 3.7 2.2 0.2 1.7 2.4 1.8 0.6 1.9 0.2 0.5 0.3 2.1 0.1 0.4 81.7 72.8 1.9 1.7 8.1 2.4 29.3 0.0 15.9 3.4 0.0 3.1 13.3 3.3 4.4 0.1 10.4 0.4 1.9 1.6 1.1 0.0 0.3 13.7 2.9 0.9 1.0 1.1 1.6 1.4 0.9 1.6 1.6 1.1 1.9 1.0 1.3 17.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 34.0 43.2 0.0 0.0 0.0 1.8 0.0 1.9 104.5 0.0 11.7 0.8 0.0 8.3 5.4 2.9 0.0 0.0 0.0 5.2 2.2 3.2 0.0 13.7 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 47.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.2 48.4 1.0 0.0 0.0 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 4.3 3.1 2.9 10.1 4.4 22.4 5.4 2.5 2.7 6.3 5.8 5.2 6.1 7.2 6.0 7.7 4.9 5.0 3.3 2.1 4.6 4.1 4.2 5.4 5.6 5.3 4.4 4.3 3.7 4.6 1.8 10.2 5.3 4.4 5.9 6.6 4.7 3.3 2.8 11.0 6.0 5.7 2.9 7.2 5.3 1.3 4.1 5.4 4.2 5.2 7.0 5.5 4.5 5.6 5.1 3.1 10.9 11.1 2.1 3.7 4.2 3.1 4.8 4.8 4.7 3.1 6.4 0.5 4.0 4.0 2.1 4.9 9.3 6.1 5.3 6.7 2.9 7.0 6.5 1.6 4.9 15.5 11.8 3.8 7.9 4.5 5.6 8.6 6.4 4.1 7.7 13.6 4.4 3.1 2.5 4.7 2.5 6.2 2.2 8.4 4.7 1.0 4.7 9.4 7.5 5.9 4.2 9.1 0.8 5.9 4.5 11.8 9.1 7.8 6.7 2.1 5.3 9.5 6.8 6.8 4.8 3.8 7.2 30.1 13.6 14.7 3.9 10.4 1.6 5.3 2.3 2.2 10.2 6.3 1.9 2.9 55.5 5.9 13.6 8.9 3.1 3.3 2.9 4.4 2.5 2.7 2.1 4.6 5.3 4.4 5.3 2.9 4.1 5.6 24.5 25.6 29.1 58.8 28.3 14.4 11.0 14.2 12.5 22.8 15.6 13.6 27.9 5.7 23.9 9.2 16.7 23.1 34.1 19.0 7.9 7.0 0.4 22.1 38.3 20.3 23.3 10.9 48.4 7.5 5.7 18.0 21.4 33.2 27.8 15.5 13.6 8.5 14.5 35.3 89.7 15.8 32.6 48.8 93.3 0.9 8.1 98.3 5.4 90.9 48.1 5.8 34.0 112.6 128.3 8.2 18.7 7.2 22.5 12.1 16.3 2.8 22.3 24.3 13.1 47.0 21.7 0.2 1.3 28.4 35.9 34.2 18.9 24.7 14.0 27.5 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.2 1.6 3.7 5.2 2.4 19.7 3.0 6.3 13.7 2.5 0.0 4.1 5.4 2.0 1.4 7.6 1.9 2.5 1.2 9.3 1.7 1.6 3.9 4.1 3.7 2.0 1.5 1.5 2.6 2.0 1.5 4.6 2.2 2.5 4.3 3.6 4.2 1.1 1.2 16.2 6.0 2.1 0.6 3.8 4.3 1.6 2.7 5.8 2.3 1.3 4.1 3.4 4.0 5.8 9.0 8.0 14.5 8.9 1.2 1.3 26.4 1.8 2.4 3.4 2.7 16.6 8.1 14.9 3.5 2.4 1.6 9.4 13.0 5.2 3.6 6.7 5.2 19.2 7.0 5.6 5.1 20.2 11.3 2.0 13.3 4.2 9.9 4.3 5.3 10.3 13.4 4.8 2.0 14.6 10.0 13.0 8.1 7.7 2.7 15.4 9.1 5.2 3.8 16.5 18.1 15.5 4.0 10.3 4.9 5.7 6.6 16.1 6.7 3.7 15.4 1.8 6.8 4.2 2.0 12.7 2.4 13.9 4.9 0.1 0.4 0.2 0.0 0.4 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.2 3.7 2.4 6.3 13.7 9.3 1.7 2.0 1.5 2.2 0.6 2.7 5.8 4.2 6.4 9.0 31.3 6.4 49.5 3.5 4.2 14.8 16.3 8.0 5.8 2.9 2.8 8.0 1.8 20.9 7.0 7.3 10.5 0.0 3.5 4.7 18.8 11.9 6.6 6.0 24.8 88.5 4.4 30.1 3.4 13.7 29.6 2.5 6.2 3.6 6.1 10.1 10.1 45.7 8.0 8.2 26.9 23.2 0.8 0.6 26.9 10.6 54.4 27.1 1.5 2.1 41.7 86.7 6.2 7.7 3.0 4.8 6.2 10.3 1.5 11.9 8.6 0.0 3.8 7.7 0.5 2.6 24.4 68.2 2.5 5.5 2.3 6.9 7.0 TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 631.4;Late spermatids: 933.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" 16.5 20.1 5.7 21.6 6.1 38.1 17.3 10.8 8.4 11.4 6.8 20.0 21.0 13.7 9.5 14.7 12.6 10.7 18.5 5.5 7.3 21.5 22.6 10.9 27.7 5.8 6.1 17.8 13.9 16.2 6.3 20.4 6.5 14.5 17.3 9.8 17.3 11.4 17.7 9.0 17.8 11.6 7.0 17.3 16.1 33.0 6.4 24.9 19.6 16.1 23.0 16.7 7.5 8.8 85.7 47.7 52.8 54.7 15.3 19.4 59.8 37.9 37.3 46.8 51.1 170.0 88.6 170.1 53.9 17.6 34.8 65.2 97.6 53.5 73.4 73.4 85.7 64.1 33.4 64.5 23.3 164.7 49.4 19.2 24.4 57.0 51.6 22.2 41.1 49.9 153.4 74.8 33.2 46.4 130.2 65.1 100.0 39.2 49.9 102.9 113.0 76.0 28.3 57.0 69.8 48.1 75.1 103.7 97.0 42.9 112.8 47.9 32.0 34.4 109.5 39.5 102.5 75.6 125.8 214.2 44.1 125.1 26.4 1.0 9.5 4.0 8.3 9.5 10.8 12.8 10.0 8.8 12.1 12.5 12.4 10.1 7.1 15.0 8.3 14.7 9.0 6.9 5.7 6.1 10.8 8.4 5.5 7.3 5.8 6.1 6.5 7.0 6.4 8.8 46.4 54.5 27.9 6.2 52.5 50.1 44.0 52.4 59.2 25.1 48.6 62.9 35.0 38.6 51.0 20.2 16.7 98.1 56.8 17.1 88.0 41.0 631.4 36.8 44.5 39.5 15.5 46.7 10.1 44.7 77.4 38.8 25.0 41.2 29.7 34.1 26.0 64.1 44.0 38.7 11.5 37.5 18.3 21.9 19.3 933.1 41.3 32.3 23.2 2.8 36.3 38.2 48.4 10.6 11.7 35.2 23.0 30.9 35.8 47.3 14.1 72.0 31.4 21.4 26.3 74.8 40.5 55.3 63.9 48.6 54.7 52.5 38.3 69.1 48.1 31.8 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 344.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 31.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: AB_783105, HPA044754: AB_2679074, HPA068909: AB_2686056, HPA077304: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favorable (7.57e-4)" "prognostic favorable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 28.2 23.5 24.3 38.6 24.0 164.0 27.2 24.5 24.4 33.5 32.5 37.8 30.5 27.6 19.4 50.1 32.8 24.6 34.3 24.1 22.8 23.2 25.9 21.8 67.1 27.5 24.4 19.3 18.4 28.5 21.3 40.6 25.3 26.1 42.4 20.2 26.1 30.8 58.2 42.8 32.3 34.3 26.6 30.8 31.3 49.6 26.8 53.4 33.1 59.0 68.3 37.5 30.1 25.7 343.2 82.5 104.4 89.5 138.4 122.7 118.5 187.8 168.7 238.1 218.6 173.3 155.9 314.6 61.3 181.3 130.3 160.3 183.0 167.1 232.2 215.9 212.8 184.4 129.2 109.8 86.8 468.3 155.7 102.1 147.3 151.3 87.4 85.0 162.7 116.2 154.1 82.6 215.5 117.7 207.0 181.4 96.6 322.7 105.0 138.9 93.0 181.1 91.3 129.1 268.2 79.3 84.8 228.8 58.7 75.1 157.9 371.7 114.4 77.2 122.9 165.6 210.8 69.5 92.4 326.4 171.9 285.2 133.2 31.9 3.0 4.6 3.1 3.8 3.4 4.4 4.1 3.7 5.9 3.6 6.3 3.2 3.8 2.3 5.5 3.0 5.3 2.5 24.3 24.0 24.5 24.4 24.1 22.8 27.5 24.4 25.3 26.6 26.8 25.7 21.4 9.6 15.8 12.7 38.8 59.8 32.1 16.1 33.6 10.3 45.6 35.2 26.6 28.6 14.7 29.5 14.6 83.2 33.8 29.8 80.3 12.3 5.5 34.4 28.2 25.8 40.2 344.3 22.5 11.9 128.0 30.8 38.7 31.0 21.0 23.3 34.6 58.7 49.2 6.7 19.5 36.1 12.2 49.1 51.2 10.7 28.6 41.1 35.6 5.6 24.8 14.7 16.5 9.5 10.2 19.0 24.2 28.2 67.3 35.7 29.4 66.5 21.0 22.5 6.6 20.0 32.7 76.7 52.7 74.6 60.0 66.6 32.1 30.3 47.4 35.8 TFIP11 "DKFZP434B194, Spp382, TIP39" ENSG00000100109 "Tuftelin interacting protein 11" Q9UBB9 22 26491225-26512505 "Plasma proteins, Predicted intracellular proteins" "Biomineralization, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027085 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA027085: AB_1857964" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" "unprognostic (4.87e-2)" "unprognostic (9.14e-2)" "unprognostic (3.24e-2)" "unprognostic (3.86e-2)" "unprognostic (6.28e-2)" "unprognostic (2.63e-1)" "unprognostic (1.76e-1)" "unprognostic (3.01e-1)" "unprognostic (4.38e-2)" "unprognostic (2.34e-1)" "unprognostic (2.96e-3)" "unprognostic (1.46e-2)" "unprognostic (9.24e-2)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" 13.5 13.0 12.4 16.3 13.5 62.8 12.5 15.4 13.9 11.5 12.1 12.7 12.9 12.4 10.4 14.8 13.1 12.6 16.0 12.9 12.0 13.9 19.3 14.0 24.9 12.0 11.8 12.4 16.7 13.0 10.5 14.5 11.3 12.4 12.6 13.4 11.0 10.6 41.8 20.3 13.5 13.1 11.6 17.7 11.9 26.6 13.0 20.1 16.2 21.5 24.7 14.8 10.9 14.3 22.9 26.4 22.3 24.6 34.7 20.6 21.5 26.4 34.5 41.8 39.1 19.8 16.1 44.4 16.6 33.9 27.6 32.8 32.1 26.3 30.3 32.3 30.4 27.4 16.4 20.2 31.4 63.6 33.2 25.9 34.9 40.0 30.9 22.3 32.6 22.4 37.4 38.9 28.2 28.2 29.2 33.8 21.4 32.2 21.9 43.6 34.6 38.8 24.2 22.4 16.7 24.0 31.9 22.7 32.8 21.4 18.7 27.7 31.6 35.2 56.8 22.4 25.6 29.8 41.8 86.6 27.8 24.6 26.8 68.7 28.4 50.1 37.2 31.3 35.1 37.9 33.0 35.2 26.1 42.9 30.9 28.4 44.9 36.3 44.1 16.4 44.5 33.0 12.4 13.5 15.4 13.9 12.9 12.0 12.0 11.8 11.3 11.6 13.0 14.3 11.3 9.6 9.7 11.4 17.8 16.8 11.2 13.2 22.2 9.7 7.5 6.3 3.5 17.2 12.3 12.9 8.4 17.9 20.7 14.8 13.7 15.1 67.9 12.2 9.2 13.3 16.2 20.2 7.1 20.7 14.4 7.8 9.2 12.6 8.2 11.9 13.2 10.8 13.3 15.2 7.2 11.2 6.1 6.2 7.8 12.3 11.1 10.4 7.2 4.7 12.3 7.7 19.6 6.0 6.5 25.3 8.4 9.8 18.6 7.6 11.4 9.3 14.1 6.9 0.0 10.1 10.6 43.6 19.4 14.2 16.8 19.4 17.4 11.6 10.7 10.9 TGFBRAP1 "TRAP-1, TRAP1, VPS3" ENSG00000135966 "Transforming growth factor beta receptor associated protein 1" Q8WUH2 2 105264391-105329735 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037672, HPA038397" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA037672: AB_2675597, HPA038397: AB_10669782" "unprognostic (1.66e-1)" "unprognostic (1.58e-2)" "unprognostic (8.99e-2)" "unprognostic (4.49e-3)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (5.63e-3)" "unprognostic (9.15e-2)" "unprognostic (2.25e-1)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (8.30e-2)" "unprognostic (8.82e-2)" "unprognostic (3.89e-1)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" 9.6 8.1 6.5 8.0 6.3 22.7 8.1 6.1 7.2 6.6 7.7 8.1 7.2 7.8 5.4 8.3 7.0 5.9 6.6 6.8 5.4 6.7 5.0 7.4 9.4 5.8 6.4 7.6 9.9 11.4 5.1 10.4 5.9 8.3 8.2 6.2 8.3 9.3 11.8 11.1 8.0 8.9 5.6 8.5 13.5 2.5 6.5 9.1 10.9 7.7 8.3 7.8 6.6 7.2 22.5 17.5 12.5 15.5 13.3 10.5 25.4 16.0 21.8 26.6 25.3 25.9 13.6 22.7 16.9 18.2 27.1 13.5 22.4 38.1 21.9 24.3 23.8 30.7 13.8 20.7 12.1 28.6 22.4 12.7 22.5 22.2 19.6 14.1 28.7 19.5 28.0 10.9 32.6 14.9 20.4 18.3 15.9 15.4 14.5 22.9 19.8 33.0 16.4 27.3 24.7 16.5 13.2 26.1 25.8 9.0 13.1 17.5 20.8 16.7 25.4 14.1 16.4 11.3 14.8 24.7 11.9 19.6 35.3 0.4 0.8 1.1 1.8 0.7 1.5 0.6 1.2 1.0 0.6 1.0 0.7 1.1 0.3 0.9 0.5 1.0 0.9 0.7 6.5 6.3 6.1 7.2 6.8 5.4 5.8 6.4 5.9 5.6 6.5 7.2 13.7 6.4 9.5 10.4 8.1 8.0 3.5 5.6 9.1 12.4 8.8 9.3 5.9 5.7 7.1 5.5 16.7 12.4 8.9 7.5 1.9 5.4 0.1 5.2 7.0 10.6 11.3 11.3 17.0 10.8 4.8 8.5 9.7 8.3 2.5 10.8 13.9 6.7 12.9 15.2 14.8 8.2 8.2 13.8 4.4 0.5 7.5 9.9 3.6 17.8 9.5 9.0 11.3 8.5 13.5 8.3 5.2 8.2 7.6 7.7 5.8 7.3 2.7 7.2 26.3 15.8 8.1 0.4 1.2 11.5 13.1 7.4 8.8 11.1 9.2 3.1 TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112274537-112285904 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 86.6;Syncytiotrophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 137.4;U-698: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA045889: AB_10963785" "unprognostic (2.41e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-3)" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.48e-2)" "unprognostic (2.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.26e-2)" "unprognostic (6.44e-3)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (2.99e-1)" "unprognostic (8.49e-3)" 6.4 6.3 2.0 19.9 1.8 40.6 13.7 4.3 2.1 7.7 4.3 7.0 6.7 5.6 2.1 15.6 6.8 7.5 10.7 2.3 2.4 5.2 11.3 10.2 32.2 2.3 2.1 9.3 41.3 11.5 2.1 14.2 2.5 6.7 6.9 2.8 34.8 3.7 3.8 9.3 8.8 5.3 2.1 11.7 10.3 2.1 2.3 15.4 21.1 6.4 34.6 11.6 7.7 2.3 21.9 5.5 7.9 13.4 9.5 7.7 15.9 17.0 32.0 10.6 18.1 2.8 19.1 66.3 13.5 6.8 15.5 6.3 10.9 13.0 22.1 54.1 6.4 6.6 12.4 6.2 6.4 21.2 8.8 10.4 7.0 11.4 12.3 18.0 17.0 18.1 6.8 137.4 14.3 11.0 37.3 11.5 1.6 13.4 7.0 63.7 19.9 44.7 23.6 14.7 18.1 18.6 13.7 28.2 6.6 3.4 12.2 29.9 12.7 16.7 19.8 14.2 13.6 85.3 84.8 123.8 15.7 13.8 12.6 6.8 7.2 4.0 11.1 5.2 18.1 38.2 20.4 19.4 13.2 40.4 9.0 11.6 21.4 17.4 6.8 12.3 33.9 11.3 2.0 1.8 4.3 2.1 2.3 2.4 2.3 2.1 2.5 2.1 2.3 2.3 35.7 19.2 27.4 0.0 44.8 21.3 15.7 27.8 43.9 1.4 31.6 30.9 15.4 12.8 15.7 12.9 0.0 47.9 23.4 4.4 19.6 16.5 0.1 10.0 9.6 31.8 9.0 7.6 1.4 24.4 20.9 22.3 14.8 21.0 3.8 5.4 6.4 10.7 17.8 0.0 0.6 8.4 28.5 13.0 29.7 1.4 9.0 13.1 33.8 2.8 7.1 12.5 11.3 0.5 0.1 11.4 8.0 10.9 86.6 29.2 11.0 9.5 8.8 0.6 6.6 27.2 10.5 2.5 3.8 39.2 26.0 79.4 35.9 5.7 7.0 15.1 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.1" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA054116: AB_2682386" "unprognostic (5.57e-2)" "prognostic favorable (2.09e-5)" "unprognostic (5.18e-2)" "unprognostic (5.13e-2)" "unprognostic (1.15e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (5.53e-2)" "unprognostic (6.74e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (4.90e-2)" "unprognostic (2.43e-1)" "unprognostic (6.71e-2)" "unprognostic (6.29e-2)" "unprognostic (2.74e-1)" 16.1 6.4 9.2 18.3 11.5 65.1 15.2 10.7 10.9 17.4 2.9 20.6 17.3 10.8 3.0 31.1 10.1 5.8 9.9 12.3 15.3 16.4 13.3 20.3 17.7 15.1 13.9 14.0 14.9 5.8 10.3 12.6 11.8 23.2 6.4 4.9 19.1 10.1 8.3 29.4 21.8 6.9 13.4 23.1 15.7 22.1 15.1 13.5 13.5 2.9 18.9 9.8 19.4 12.2 7.8 24.2 13.3 23.6 12.1 9.9 80.3 1.5 4.1 3.1 2.5 34.0 22.8 22.0 32.8 2.1 4.8 14.3 32.3 11.5 1.6 30.9 45.9 36.9 50.8 6.6 11.5 11.4 51.1 20.5 6.3 9.1 8.2 19.7 15.5 47.9 26.1 96.0 4.5 20.9 41.2 28.3 14.2 7.4 24.9 36.8 13.6 24.7 7.1 41.7 19.5 28.7 66.2 29.7 28.7 14.5 33.6 24.9 11.7 9.5 18.7 29.6 16.4 84.6 57.2 35.3 13.3 37.3 25.1 2.6 4.5 2.5 1.9 4.8 1.8 9.9 2.6 2.5 2.9 4.9 2.5 3.3 49.1 2.8 5.2 8.7 1.6 1.7 9.2 11.5 10.7 10.9 12.3 15.3 15.1 13.9 11.8 13.4 15.1 12.2 27.5 12.8 27.7 16.0 49.2 115.1 47.8 19.5 59.2 19.9 45.5 28.4 8.1 4.3 18.9 62.5 31.3 25.3 38.2 55.2 7.9 11.6 45.5 17.2 5.0 27.6 28.8 15.2 6.1 5.6 64.4 25.0 17.9 32.1 53.2 25.5 23.9 21.5 37.3 0.0 5.0 30.3 10.2 41.5 78.2 76.9 14.0 51.5 35.6 13.1 35.8 32.6 1.0 9.5 0.4 11.0 31.7 18.4 47.2 39.9 41.0 13.2 8.1 4.4 0.0 39.8 24.7 5.8 28.0 67.7 132.8 82.4 37.6 0.7 43.9 31.5 TMCO3 "C13orf11, FLJ20623" ENSG00000150403 "Transmembrane and coiled-coil domains 3" Q6UWJ1 13 113491021-113554590 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 20.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039561, HPA048126" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA039561: AB_2676573, HPA048126: AB_2680276" "unprognostic (7.89e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (6.78e-2)" "unprognostic (7.88e-2)" "unprognostic (2.89e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (2.93e-2)" "unprognostic (9.44e-2)" "unprognostic (3.08e-3)" "unprognostic (2.76e-2)" "unprognostic (8.47e-3)" "unprognostic (3.70e-3)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (6.27e-3)" "prognostic unfavorable (4.10e-4)" 24.2 26.9 20.5 18.6 18.3 76.7 22.7 29.8 21.5 31.1 49.2 23.1 21.0 33.1 20.0 14.4 25.2 27.7 28.2 17.3 16.3 24.2 14.3 24.3 16.3 19.4 18.8 25.2 40.7 35.1 23.1 30.1 19.4 22.1 22.0 18.1 38.7 21.6 19.1 13.4 22.7 29.6 19.6 19.8 44.3 16.1 19.6 12.4 10.7 15.2 13.1 19.6 18.9 21.2 97.8 32.6 46.3 32.0 93.1 136.4 25.0 105.0 99.6 45.1 45.3 35.7 41.9 23.1 25.9 115.7 61.7 38.5 24.8 38.0 70.0 48.0 25.1 20.9 52.2 36.0 87.9 34.3 41.7 112.0 88.5 33.9 68.9 116.7 74.5 14.3 30.3 31.6 79.6 17.5 18.0 20.6 23.2 46.5 50.9 22.4 28.0 16.7 74.3 12.6 40.4 33.5 32.3 70.3 33.6 65.3 41.5 64.6 117.4 50.3 53.5 36.9 44.8 39.2 23.9 14.8 167.2 17.8 24.6 3.1 8.3 8.5 1.3 5.6 1.5 3.1 1.5 2.0 6.0 1.8 1.7 1.7 20.2 5.0 11.3 1.3 1.5 2.7 20.5 18.3 29.8 21.5 17.3 16.3 19.4 18.8 19.4 19.6 19.6 21.2 34.3 12.8 15.1 21.5 12.5 9.8 37.2 25.8 21.6 16.4 39.2 17.5 20.3 24.3 27.8 25.8 14.6 21.6 13.5 37.1 5.9 46.8 14.6 28.2 39.2 31.3 34.2 23.5 42.9 37.4 53.8 35.0 39.3 28.6 26.6 18.4 35.0 12.4 19.1 21.9 41.0 69.2 12.2 31.3 18.8 37.1 36.7 24.5 17.8 12.2 31.4 25.9 17.5 24.6 31.9 52.6 28.2 47.8 19.2 64.0 20.0 11.2 45.2 19.0 6.6 26.2 31.9 17.6 12.2 15.9 7.1 13.0 11.8 34.4 17.7 31.3 TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.49e-1)" "unprognostic (1.18e-1)" "unprognostic (2.95e-2)" "unprognostic (1.52e-3)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (7.97e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "prognostic favorable (2.36e-9)" "unprognostic (4.37e-2)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (1.53e-3)" 8.2 9.8 7.7 10.6 10.6 36.6 6.0 9.2 9.0 7.7 7.9 12.1 14.5 8.0 6.0 8.4 7.6 7.8 7.2 7.4 9.3 9.2 12.7 8.0 11.9 11.3 10.2 10.2 10.2 3.9 8.7 10.2 9.9 7.6 10.1 14.9 6.5 3.2 3.7 7.8 13.7 6.3 9.3 9.2 7.3 17.4 8.5 6.8 9.7 4.9 9.7 8.1 7.8 16.9 14.2 17.1 21.8 22.3 9.5 7.7 38.9 9.2 5.2 7.4 11.3 35.3 30.7 19.6 17.0 4.4 16.4 25.9 18.3 8.9 13.0 12.0 11.4 10.6 16.4 22.4 6.3 25.3 27.3 6.7 6.8 12.5 9.4 8.7 6.5 22.7 21.8 15.2 3.9 28.8 22.3 16.8 26.1 17.2 9.2 43.5 8.5 15.7 5.1 18.3 12.8 14.9 22.4 7.0 12.6 25.6 9.4 11.6 9.6 12.6 21.4 10.1 10.2 13.7 17.3 60.3 9.8 14.7 14.4 14.5 26.6 38.2 27.9 29.1 36.6 28.9 29.1 31.8 24.0 28.8 30.9 27.3 33.3 25.4 26.9 26.8 23.1 21.6 7.7 10.6 9.2 9.0 7.4 9.3 11.3 10.2 9.9 9.3 8.5 16.9 39.7 19.2 15.0 20.5 49.0 19.9 45.7 37.8 26.7 25.6 37.7 27.1 9.3 40.0 25.3 20.2 37.5 73.0 65.0 86.2 25.4 26.8 40.5 62.5 23.6 37.2 34.1 17.1 17.6 19.3 51.5 24.3 16.8 67.7 28.6 57.3 35.3 24.2 37.2 37.0 15.9 37.6 22.4 31.8 29.7 8.7 24.2 38.3 21.4 11.2 41.2 43.7 42.2 24.1 29.8 23.3 67.6 21.4 29.2 57.5 53.5 30.2 32.4 38.3 32.9 19.9 20.1 88.5 61.8 19.7 20.0 53.4 49.0 36.7 56.0 67.8 TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "dendritic cells: 39.9;Kupffer cells: 20.7;Langerhans cells: 25.7;Macrophages: 26.2;monocytes: 25.5;NK-cells: 54.6;T-cells: 35.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HDLM-2: 54.5;Karpas-707: 11.1;U-937: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" 5.6 2.0 1.0 13.1 1.3 33.5 8.5 1.0 9.7 2.5 2.2 11.3 2.2 1.3 1.1 2.8 1.9 5.5 37.1 1.1 1.8 2.6 3.9 8.2 13.2 1.6 1.3 1.0 2.4 0.7 1.1 1.8 2.1 2.0 3.4 0.5 5.7 2.2 1.6 1.1 7.3 3.6 1.1 18.4 2.8 1.0 2.4 19.2 2.0 4.6 10.6 4.6 1.9 1.6 0.4 0.0 4.9 0.0 0.0 0.0 0.0 1.3 12.7 0.5 0.9 0.0 0.0 0.1 0.6 4.1 0.1 0.0 0.0 0.3 1.5 54.5 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.1 0.0 0.1 2.0 1.4 1.0 6.7 0.0 11.1 2.4 0.0 2.9 2.2 1.2 0.0 0.4 0.1 1.8 0.8 4.8 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 2.1 0.5 0.9 1.2 5.7 0.1 2.9 0.0 9.0 31.6 3.7 61.9 55.9 101.6 31.3 16.1 57.9 6.6 22.8 22.2 33.7 4.7 33.9 25.1 269.0 12.9 14.7 1.1 3.0 39.0 1.0 1.3 1.0 9.7 1.1 1.8 1.6 1.3 2.1 1.1 2.4 1.6 0.5 0.0 3.0 0.0 6.9 0.9 1.0 2.5 0.6 0.0 4.2 2.7 15.9 0.0 5.5 0.0 0.0 0.0 39.9 0.1 0.0 0.0 6.5 0.1 0.3 1.5 0.0 8.8 0.5 0.0 0.0 4.1 1.1 0.2 1.3 0.0 3.3 0.2 3.2 0.0 1.3 0.2 0.0 20.7 25.7 5.1 0.0 26.2 5.4 17.8 25.5 1.9 54.6 0.0 0.1 0.1 0.0 0.0 11.3 0.1 0.0 0.4 2.9 0.0 0.0 3.7 0.8 0.0 0.6 0.4 0.3 0.3 35.9 0.1 0.0 4.5 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883312 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 519.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 774.9;Endometrial ciliated cells: 605.2;Glandular and luminal cells: 1498.3;Macrophages: 596.6;Suprabasal keratinocytes: 745.7;T-cells: 624.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 106.5;Karpas-707: 161.3;REH: 151.5;U-266/84: 131.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 57.0 15.6 4.4 114.6 3.8 519.5 23.3 2.9 23.9 27.5 12.0 22.6 21.4 31.3 5.2 26.6 23.4 47.8 23.0 3.2 2.8 13.8 27.4 56.2 76.8 6.1 3.9 73.2 25.8 25.8 7.5 28.9 6.7 17.3 24.7 19.1 16.1 10.3 8.6 50.5 30.7 33.5 6.6 46.1 22.8 8.3 9.5 71.1 11.7 3.8 55.7 171.1 14.6 6.2 32.6 4.8 1.8 2.8 10.1 16.9 7.8 18.8 67.6 4.8 5.7 34.9 8.8 7.3 43.1 20.0 106.5 22.6 1.1 50.4 8.9 46.8 2.2 7.5 19.8 21.1 11.2 10.3 12.8 15.6 7.3 56.4 53.6 5.6 2.9 21.2 17.4 161.3 8.4 1.8 56.2 41.4 1.5 2.1 1.4 151.5 39.4 6.1 14.8 15.1 0.7 0.3 3.6 5.3 16.9 7.0 3.4 11.7 14.8 46.9 6.8 46.0 9.6 48.7 131.4 14.0 16.9 13.1 6.1 7.3 12.6 9.6 19.6 9.3 27.9 7.4 19.4 18.0 14.3 7.8 13.1 10.1 13.6 11.1 5.1 26.2 19.2 14.8 4.4 3.8 2.9 23.9 3.2 2.8 6.1 3.9 6.7 6.6 9.5 6.2 71.8 38.5 76.3 2.0 94.5 774.9 150.2 102.1 384.7 1.1 29.0 42.3 4.6 25.8 53.7 0.0 29.2 8.1 395.5 53.9 1.9 60.0 2.6 605.2 365.9 114.8 11.9 5.2 0.1 26.9 104.8 110.1 111.1 1498.3 255.9 2.3 48.5 13.5 45.7 0.0 0.3 38.6 67.1 125.2 461.8 3.2 6.8 596.6 129.9 8.4 59.1 1.7 14.4 2.0 0.3 30.5 29.5 6.0 331.4 170.2 37.3 3.1 84.3 13.3 6.6 29.0 94.9 2.7 2.2 367.9 745.7 23.1 624.2 14.9 20.9 78.1 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MOLT-4: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 14.0 17.4 7.3 9.4 6.1 48.2 13.7 2.5 7.8 23.2 4.0 12.6 7.6 11.7 4.8 18.4 13.4 9.2 7.6 8.5 5.8 14.4 30.3 10.5 12.0 7.0 4.7 32.1 18.9 10.1 9.2 7.4 7.1 13.2 9.7 2.0 14.2 8.1 7.3 22.6 11.6 7.8 2.9 12.6 12.9 23.4 5.4 21.4 21.9 3.4 11.4 17.8 19.1 6.4 25.5 38.3 15.8 59.4 22.0 24.5 28.1 11.6 14.8 20.5 21.1 48.4 35.8 74.2 42.6 16.2 14.7 26.8 33.8 21.3 17.6 29.5 52.4 65.6 21.5 49.5 24.8 44.4 68.4 25.1 22.3 17.4 24.8 17.7 25.0 21.1 80.5 28.2 18.3 106.3 197.8 87.9 27.6 54.9 65.4 24.7 20.7 112.2 15.3 40.4 28.1 34.1 33.2 29.3 61.7 19.3 19.3 72.5 16.5 14.3 57.7 16.4 30.2 15.2 17.0 38.0 24.1 64.9 17.4 31.4 10.5 0.5 6.2 6.3 6.3 28.9 11.3 8.6 35.3 14.4 24.2 18.8 0.7 0.4 1.2 30.9 3.2 9.2 7.3 6.1 2.5 7.8 8.5 5.8 7.0 4.7 7.1 2.9 5.4 6.4 11.4 6.4 8.6 3.3 11.9 23.7 32.3 13.1 14.2 1.2 15.3 11.6 3.3 10.0 10.5 9.2 0.0 11.7 7.3 6.7 7.9 11.4 29.3 3.9 10.9 7.7 4.9 41.3 2.5 9.3 23.6 8.9 5.6 5.8 7.0 24.7 6.4 12.1 11.1 3.3 3.5 11.3 2.0 8.8 24.9 11.1 8.7 9.4 21.4 0.0 9.3 1.4 2.1 1.5 2.9 7.1 11.2 4.5 6.1 29.7 2.8 15.8 3.1 0.2 6.6 13.5 10.0 31.3 36.4 17.8 23.9 10.1 8.6 21.4 20.8 22.8 TRAF6 RNF85 ENSG00000175104 "TNF receptor associated factor 6" Q9Y4K3 11 36483769-36510272 "Enzymes, Predicted intracellular proteins" "DNA damage, Immunity, Osteogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004605, HPA019805, HPA020599" Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" Mitochondria Nucleoli "CAB004605: AB_628391, HPA019805: AB_1858231, HPA020599: AB_1858232" "unprognostic (2.48e-2)" "unprognostic (1.38e-1)" "unprognostic (2.83e-1)" "unprognostic (8.73e-2)" "unprognostic (1.71e-1)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.16e-2)" "unprognostic (9.22e-2)" "prognostic favorable (1.36e-4)" "unprognostic (2.82e-2)" "unprognostic (1.20e-1)" "unprognostic (3.92e-2)" "unprognostic (1.07e-1)" 6.5 5.1 4.3 5.3 5.2 23.3 5.8 4.6 5.8 6.1 4.7 5.7 6.0 6.4 5.7 6.4 6.2 5.7 7.5 4.8 4.4 6.7 7.9 7.9 6.3 4.7 4.5 7.9 7.2 6.0 4.0 6.2 4.5 5.0 6.3 5.4 5.9 5.4 7.0 6.4 7.6 7.5 3.7 8.4 5.7 7.8 4.8 9.5 9.6 8.0 7.1 5.5 6.2 6.5 5.1 6.3 12.0 6.8 11.0 7.9 5.1 7.5 8.0 6.8 8.8 5.6 3.3 6.7 4.5 8.0 7.8 9.4 9.6 7.6 11.2 11.0 11.1 6.4 5.0 5.0 7.1 7.2 7.5 7.5 10.5 3.6 11.1 6.6 9.7 8.7 9.7 7.1 8.7 6.2 11.6 4.0 6.5 5.8 5.7 7.5 16.2 3.8 8.2 10.4 1.9 10.4 7.5 7.1 5.3 8.0 8.3 6.9 7.7 9.6 8.5 8.9 9.2 8.2 7.4 7.1 5.4 5.0 7.3 59.5 12.4 34.6 17.8 17.9 17.4 17.1 15.0 17.5 12.3 13.6 14.5 19.0 17.5 16.2 13.7 7.2 13.2 14.5 4.3 5.2 4.6 5.8 4.8 4.4 4.7 4.5 4.5 3.7 4.8 6.5 9.1 9.6 5.1 13.1 12.1 12.7 13.8 6.5 6.8 2.7 5.3 3.6 7.0 7.2 4.0 3.7 6.2 6.6 12.3 8.1 5.9 8.7 7.3 6.3 6.3 12.1 4.2 7.4 29.0 7.2 6.2 6.5 6.6 10.4 19.0 5.5 19.2 6.0 7.2 8.4 24.0 5.8 8.2 8.5 13.6 3.4 2.5 7.8 7.2 17.8 9.1 4.6 8.2 11.1 29.1 7.9 8.2 4.1 10.8 10.4 10.0 5.5 3.1 2.9 13.1 6.6 9.5 15.2 9.3 8.0 12.5 6.4 10.9 4.4 3.9 11.6 TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.9;Inhibitory neurons: 111.4;Microglial cells: 52.5;Oligodendrocyte precursor cells: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 144.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: AB_2672381, HPA051273: AB_2681416, HPA059943: AB_2684173" "unprognostic (5.85e-3)" "unprognostic (4.38e-2)" "unprognostic (2.39e-1)" "unprognostic (3.28e-3)" "unprognostic (6.64e-2)" "unprognostic (3.92e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (2.05e-4)" "unprognostic (2.67e-1)" "unprognostic (1.16e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (8.60e-2)" "unprognostic (5.39e-2)" "unprognostic (6.05e-2)" "unprognostic (2.78e-2)" 3.4 5.7 1.3 5.8 2.2 13.9 2.6 1.1 3.8 7.7 0.0 3.7 3.2 6.0 2.9 8.8 5.1 3.9 1.8 0.8 0.6 2.9 1.0 2.9 7.7 0.3 0.7 7.1 1.6 3.9 3.5 2.6 0.0 5.4 3.4 2.0 2.3 3.6 1.1 6.4 4.7 3.9 0.2 7.2 4.2 6.0 1.6 10.3 2.0 1.2 5.0 7.0 8.0 0.8 13.7 9.4 10.3 13.2 4.7 10.4 14.5 10.2 16.2 11.4 9.4 0.1 7.1 12.7 2.2 15.5 15.6 16.2 13.2 12.6 9.1 144.3 1.0 13.7 8.0 0.0 3.2 25.4 42.1 4.3 17.3 10.2 4.1 10.3 0.0 8.5 0.1 4.1 5.0 3.0 6.6 42.9 11.3 10.1 9.6 11.8 0.8 4.7 6.7 16.7 8.3 4.4 6.1 0.2 1.0 5.6 5.9 34.1 4.5 6.5 7.5 10.7 2.9 1.7 9.5 13.7 4.4 22.7 0.1 1.1 0.6 4.6 1.5 0.2 1.4 0.2 1.1 1.3 0.7 0.0 0.9 1.0 2.0 1.5 0.1 0.6 1.2 0.7 1.3 2.2 1.1 3.8 0.8 0.6 0.3 0.7 0.0 0.2 1.6 0.8 2.7 3.2 1.3 37.9 3.6 8.3 2.9 3.2 6.2 9.9 4.1 2.5 1.9 1.5 5.9 5.5 0.0 3.4 20.9 8.4 0.0 1.8 2.7 3.3 16.2 5.4 3.0 0.4 96.9 1.0 0.9 11.8 11.2 1.7 12.0 14.7 6.4 0.3 2.6 8.4 111.4 2.1 4.1 4.7 10.4 3.2 14.0 8.0 3.6 52.5 7.9 4.2 12.3 80.4 3.8 1.2 2.5 22.2 7.2 1.6 1.0 0.2 8.5 0.5 26.3 4.4 7.9 10.0 7.4 23.5 7.4 1.2 18.0 4.2 3.8 4.3 TRGC1 "C1, TCRGC1" ENSG00000211689 "T cell receptor gamma constant 1" 7 38257879-38265678 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 31.7;prostate: 76.6" "Group enriched" "Detected in some" 5 "dendritic cells: 95.8;NK-cells: 230.7;Prostatic glandular cells: 61.9;T-cells: 65.6" "Cancer enriched" "Detected in some" 141 "prostate cancer: 107.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "gdT-cell: 384.7" "Lineage enriched" "Detected in many" 4 "T-cells: 384.7" "Cell line enhanced" "Detected in some" "HL-60: 21.0;MCF7: 89.8;SK-BR-3: 49.6;U-937: 45.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.37e-2)" "unprognostic (2.38e-4)" "unprognostic (3.43e-3)" "unprognostic (6.04e-4)" "unprognostic (1.04e-2)" "unprognostic (3.77e-3)" "unprognostic (1.33e-3)" "unprognostic (3.80e-2)" "unprognostic (3.55e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (2.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "unprognostic (8.36e-2)" "unprognostic (2.56e-2)" 0.6 0.2 1.6 1.1 1.6 31.7 2.1 1.4 2.0 0.1 1.1 0.5 1.0 0.2 0.5 0.1 0.3 1.0 0.2 1.4 1.4 0.8 0.8 1.9 2.0 1.7 1.5 0.1 0.0 0.0 0.2 0.5 1.6 76.6 0.6 0.0 0.4 0.2 0.1 0.1 1.4 0.2 1.6 6.0 0.6 0.4 2.1 7.0 0.3 0.0 1.3 0.6 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 21.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 49.6 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 3.8 0.3 0.5 384.7 0.4 56.7 0.2 6.8 33.5 0.3 0.0 2.3 21.7 1.8 87.5 0.3 0.5 0.1 43.7 1.6 1.6 1.4 2.0 1.4 1.4 1.7 1.5 1.6 1.6 2.1 1.5 0.5 0.0 1.1 0.0 2.1 0.0 1.3 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.6 0.0 0.0 0.0 95.8 0.1 0.0 0.0 2.3 0.0 0.1 0.5 1.2 2.7 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 2.2 0.9 0.1 0.0 0.0 0.2 0.0 1.9 0.0 0.9 0.0 2.1 0.0 0.0 19.5 0.0 230.7 0.0 0.0 0.0 0.0 0.0 14.3 61.9 0.0 0.3 0.7 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 65.6 0.0 0.3 1.2 TRGJP "JP, TCRGJP" ENSG00000211691 "T cell receptor gamma joining P" 7 38273587-38273647 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "bone marrow: 43.1;prostate: 95.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 46 "gdT-cell: 2370.0" "Lineage enriched" "Detected in many" 46 "T-cells: 2370.0" "Group enriched" "Detected in some" 10 "MCF7: 26.9;SK-BR-3: 60.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" 0.0 0.0 1.4 5.2 1.0 43.1 0.7 0.3 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 1.1 1.2 0.8 0.7 1.2 0.0 0.0 0.4 1.1 0.8 0.0 0.0 0.0 0.0 0.4 1.1 95.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6.7 2.8 2.5 1.5 0.6 0.0 0.0 0.6 1.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 1.7 0.5 2370.0 3.2 49.6 0.8 2.0 26.9 0.8 0.3 0.4 18.5 10.2 51.9 0.9 2.0 0.6 210.4 1.4 1.0 0.3 1.4 0.8 0.7 1.1 0.8 1.1 0.6 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRIM10 "HERF1, RFB30, RNF9" ENSG00000204613 "Tripartite motif containing 10" Q9UDY6 6 30151943-30161211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.8;kidney: 2.0;liver: 2.9" "Cell type enriched" "Detected in some" 21 "Erythroid cells: 126.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "HEL: 22.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "hippocampal formation: 3.4" HPA043325 Uncertain NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA043325: AB_2678428" "unprognostic (2.98e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (2.13e-1)" "unprognostic (2.98e-1)" "unprognostic (9.53e-3)" "unprognostic (6.32e-2)" "unprognostic (2.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.74e-3)" "unprognostic (1.46e-2)" "unprognostic (4.37e-2)" "unprognostic (1.22e-2)" 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.1 0.0 1.6 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 126.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.9 0.0 0.0 0.0 3.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 19.9;heart muscle: 11.4;lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "dendritic cells: 44.6;Erythroid cells: 20.6;granulocytes: 30.4;Langerhans cells: 19.6;NK-cells: 87.6;T-cells: 21.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "HEL: 15.0;HL-60: 6.6;NB-4: 5.3;THP-1: 5.6;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA024135: AB_1858409" "unprognostic (7.50e-3)" "unprognostic (4.88e-4)" "unprognostic (1.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.45e-3)" "unprognostic (2.10e-4)" "unprognostic (7.72e-3)" "unprognostic (8.25e-3)" "unprognostic (9.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (4.20e-1)" "unprognostic (4.35e-1)" "unprognostic (8.13e-2)" 0.5 0.5 0.2 1.6 0.2 19.9 0.3 0.5 0.2 1.1 0.0 0.5 0.3 0.7 0.2 0.4 0.5 1.4 11.4 0.2 0.3 0.2 0.4 2.0 5.5 0.5 0.3 0.5 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.9 0.5 0.3 0.6 0.5 0.0 0.1 3.5 0.9 0.2 0.2 0.9 0.2 0.2 2.4 0.7 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 15.0 0.0 0.1 0.6 6.6 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.9 0.0 40.5 31.8 4.2 25.8 40.9 16.5 2.4 9.1 22.7 32.2 1.1 7.2 27.1 17.3 58.6 46.0 1.6 13.2 21.7 0.2 0.2 0.5 0.2 0.2 0.3 0.5 0.3 0.3 0.1 0.2 0.5 0.5 0.0 6.7 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.2 0.1 15.9 0.0 0.6 0.0 0.0 0.1 44.6 0.0 0.0 0.0 0.8 0.1 0.3 0.8 0.0 20.6 0.0 0.0 0.3 1.3 0.5 0.0 30.4 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 6.5 19.6 4.1 0.9 13.6 1.8 1.0 14.4 0.2 87.6 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.2 1.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 21.9 0.0 0.0 0.1 TUBGCP3 "GCP3, SPBC98, Spc98p" ENSG00000126216 "Tubulin gamma complex associated protein 3" Q96CW5 13 112485011-112588205 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043913 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA043913: AB_10963220" "unprognostic (6.12e-2)" "unprognostic (7.70e-3)" "unprognostic (1.94e-1)" "unprognostic (3.81e-1)" "unprognostic (6.86e-2)" "unprognostic (2.09e-1)" "unprognostic (6.26e-3)" "unprognostic (3.89e-2)" "unprognostic (8.70e-3)" "unprognostic (1.62e-2)" "unprognostic (3.98e-2)" "unprognostic (2.91e-2)" "unprognostic (1.23e-1)" "unprognostic (5.18e-2)" "unprognostic (8.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.38e-2)" 12.8 10.0 4.8 12.1 6.3 31.2 10.9 6.0 5.2 12.5 5.1 10.7 8.7 13.1 6.5 10.7 11.7 8.9 9.4 4.3 5.6 8.7 14.7 10.6 14.9 5.9 5.1 17.9 10.4 8.7 7.8 9.7 5.9 8.2 10.0 11.7 10.4 8.4 12.1 14.1 11.2 12.5 4.6 14.9 9.6 16.8 5.8 19.1 10.6 8.9 13.3 11.0 11.8 8.8 48.1 20.5 29.6 17.5 12.0 15.0 25.5 21.6 22.8 29.1 25.7 22.4 40.5 34.2 12.0 20.5 29.1 31.2 27.8 24.4 38.2 26.9 34.1 35.8 28.3 18.6 12.4 102.6 32.2 11.7 18.4 19.0 34.1 11.9 23.3 33.0 19.7 23.2 21.9 19.6 41.3 34.9 17.5 51.0 20.7 48.6 26.6 23.0 12.4 19.8 27.4 25.1 26.0 34.2 14.5 17.4 20.7 79.8 18.6 16.6 51.8 19.5 27.1 23.8 18.7 47.7 28.1 68.7 34.4 19.0 33.8 50.0 10.9 28.3 13.4 17.5 11.8 13.7 37.4 11.2 17.9 11.4 31.6 19.0 25.0 19.9 16.2 18.7 4.8 6.3 6.0 5.2 4.3 5.6 5.9 5.1 5.9 4.6 5.8 8.8 14.9 9.6 8.7 25.8 16.6 11.6 5.5 4.9 14.8 18.6 7.6 6.7 9.6 7.2 9.2 9.2 16.7 8.8 18.5 7.5 0.0 6.7 22.9 5.8 12.2 11.9 8.4 23.5 45.9 6.2 11.6 12.0 16.3 7.1 7.0 13.3 12.8 14.7 14.6 28.6 44.4 7.4 2.0 22.5 13.0 24.6 14.9 20.0 19.6 34.7 19.0 11.5 14.4 42.3 49.3 8.6 4.0 10.9 18.5 4.3 7.4 9.7 3.9 16.4 26.3 13.0 11.5 25.0 31.4 12.2 8.2 4.1 13.3 12.0 8.4 3.9 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.9;testis: 158.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 341.4;dendritic cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 16.3 17.6 17.1 21.8 17.3 115.9 11.0 15.7 23.7 16.8 10.9 18.5 11.4 17.2 5.5 37.1 15.1 13.1 24.8 25.2 23.8 13.0 11.5 16.2 35.7 17.0 16.5 14.8 7.7 6.8 28.8 13.6 22.2 15.1 9.3 9.4 12.0 6.2 15.5 12.0 16.2 15.0 16.7 25.7 17.6 158.3 18.9 47.8 10.3 5.7 30.9 16.2 17.8 21.3 532.9 279.4 241.3 193.8 15.3 21.6 42.9 419.3 126.1 253.2 229.1 191.1 183.6 508.6 169.5 106.4 304.5 152.9 243.6 109.5 111.4 402.0 810.5 305.8 162.8 62.5 45.1 370.0 286.0 23.8 30.2 186.7 179.1 55.0 100.6 272.7 310.0 347.0 161.3 139.5 503.2 191.3 605.3 147.2 470.6 437.4 185.5 185.8 69.2 111.5 609.3 330.0 534.5 131.2 248.6 72.6 93.8 198.1 155.9 151.9 432.8 130.7 1013.5 277.1 734.4 617.0 159.2 257.5 562.7 0.5 0.8 1.3 0.7 0.6 0.5 2.5 1.0 1.0 0.6 0.6 1.0 0.5 2.4 0.2 0.4 1.3 0.4 0.1 17.1 17.3 15.7 23.7 25.2 23.8 17.0 16.5 22.2 16.7 18.9 21.3 308.0 0.0 3.4 5.9 161.3 162.6 151.2 31.5 81.4 59.3 235.9 341.4 3.1 8.6 9.9 20.2 54.2 87.8 432.7 59.2 15.6 42.8 127.5 89.3 68.2 72.5 92.6 166.5 8.7 30.5 247.9 99.3 44.9 68.0 18.4 200.9 31.8 10.6 65.5 32.0 11.0 69.1 38.7 26.8 125.3 52.2 17.4 131.7 74.7 3.7 36.7 91.1 21.6 7.5 13.5 82.3 44.1 12.4 100.6 82.9 20.4 18.4 9.7 75.7 13.1 125.2 186.7 196.9 174.0 74.1 115.9 59.8 233.3 64.6 55.8 121.1 UBN1 ENSG00000118900 "Ubinuclein 1" Q9NPG3 16 4846665-4882401 "Predicted intracellular proteins" "Host-virus interaction" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 14.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 14.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061029, HPA069036, HPA069045" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA061029: AB_2684420, HPA069036: , HPA069045: AB_2686072" "unprognostic (8.20e-2)" "unprognostic (1.01e-1)" "unprognostic (8.99e-3)" "unprognostic (1.75e-1)" "unprognostic (1.65e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-3)" "unprognostic (6.53e-3)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (6.89e-2)" 14.7 12.3 8.3 14.5 7.9 48.9 12.9 10.5 8.3 14.9 12.4 13.9 14.7 12.4 6.5 25.0 11.9 11.8 20.8 9.1 5.9 10.5 13.6 13.5 15.4 6.6 6.9 13.3 14.1 12.2 10.1 11.5 5.8 11.6 14.3 20.1 15.7 9.6 22.9 15.8 14.6 13.8 6.2 21.5 12.7 37.4 8.0 22.5 11.4 19.5 15.5 11.6 16.5 8.0 21.0 26.0 29.5 29.3 25.3 23.6 23.7 25.7 24.5 29.6 28.4 21.7 24.4 39.2 23.1 25.3 32.1 27.2 38.2 23.6 25.0 38.4 19.0 32.2 35.0 17.1 24.3 39.4 33.6 15.8 30.6 34.4 36.7 22.5 39.3 38.3 53.6 32.5 22.0 30.1 43.6 18.0 25.1 21.8 19.3 67.5 36.6 37.5 15.5 24.0 39.9 22.0 44.7 36.4 22.3 21.8 36.0 34.6 39.7 31.3 29.5 102.5 32.4 30.4 34.7 77.5 18.5 24.5 53.9 1.7 1.2 0.9 1.4 1.1 1.0 0.9 1.0 1.3 0.8 1.0 1.1 0.7 14.2 1.0 0.9 1.7 0.9 0.9 8.3 7.9 10.5 8.3 9.1 5.9 6.6 6.9 5.8 6.2 8.0 8.0 31.2 9.6 15.9 17.3 31.9 18.0 22.0 7.5 30.1 59.9 23.6 20.3 25.5 22.8 9.8 9.2 110.5 28.1 51.3 41.1 7.9 16.7 46.2 39.2 36.8 36.4 30.9 32.4 17.9 18.2 23.3 22.9 29.6 29.8 7.6 27.9 28.5 31.0 23.2 50.5 16.8 27.4 8.2 33.2 21.5 57.8 29.2 37.0 26.6 30.0 28.9 27.9 61.8 19.6 20.3 27.7 33.4 22.6 44.0 33.4 27.4 13.3 16.4 100.8 13.1 26.8 21.8 153.8 128.4 30.9 22.3 29.1 40.4 35.2 26.8 27.3 UGGT1 "HUGT1, UGCGL1" ENSG00000136731 "UDP-glucose glycoprotein glucosyltransferase 1" Q9NYU2 2 128091200-128195677 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012761, HPA015127" Enhanced Uncertain Cytosol NA NA 4000000 "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012761: AB_1858597, HPA015127: AB_1858596" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.14e-2)" "unprognostic (1.87e-1)" "unprognostic (4.63e-2)" "unprognostic (6.45e-2)" "unprognostic (7.03e-3)" "unprognostic (3.13e-2)" "unprognostic (3.02e-2)" "unprognostic (1.05e-1)" "unprognostic (4.09e-3)" "unprognostic (7.05e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.86e-1)" "unprognostic (1.50e-1)" "unprognostic (2.23e-2)" "unprognostic (8.38e-3)" 8.1 8.5 4.2 13.7 4.6 21.8 7.6 4.8 6.5 9.1 5.0 12.4 9.0 7.3 19.9 8.0 6.5 6.5 8.0 4.3 4.6 8.2 14.9 8.4 12.3 4.7 4.4 5.1 14.8 8.7 6.5 8.7 5.0 8.7 10.0 9.7 8.6 6.2 13.2 8.8 10.2 6.2 4.0 9.4 10.7 6.4 4.8 11.7 10.4 13.0 12.6 7.5 6.6 5.6 34.8 11.8 22.0 47.6 28.0 22.3 34.3 39.4 16.7 12.7 11.3 26.0 24.9 49.4 15.4 28.3 11.3 25.3 16.8 16.8 25.5 31.5 8.2 43.4 14.9 82.3 28.0 58.6 25.9 16.3 13.0 25.4 23.0 25.0 29.8 19.8 28.4 25.6 26.9 24.4 23.5 33.5 39.5 24.0 12.4 19.2 21.3 20.9 23.8 25.2 11.7 17.4 27.3 36.0 24.4 22.5 14.4 40.2 43.1 34.6 24.4 20.1 28.4 27.3 40.4 22.3 29.3 31.4 32.6 3.8 2.5 2.5 2.3 2.5 2.3 1.6 1.9 2.1 1.9 3.3 1.6 2.3 3.7 1.9 2.5 3.1 1.6 1.4 4.2 4.6 4.8 6.5 4.3 4.6 4.7 4.4 5.0 4.0 4.8 5.6 14.6 35.3 24.7 24.8 14.3 8.2 6.4 11.1 5.7 19.8 11.2 7.1 16.7 12.8 20.7 3.7 22.9 10.5 22.1 21.5 1.9 14.0 9.2 18.4 27.7 16.5 22.8 31.5 40.6 19.5 20.1 16.6 21.9 22.2 11.4 20.8 17.9 39.7 16.6 20.2 37.6 21.9 8.2 25.4 16.4 2.3 14.9 20.0 14.2 32.8 26.0 7.5 15.5 31.2 46.5 19.4 10.4 13.5 31.5 13.3 25.3 8.4 12.7 20.2 6.6 18.5 13.3 10.0 8.5 9.4 10.7 10.8 18.9 16.0 22.8 10.1 UHRF2 "MGC33463, NIRF, RNF107, TDRD23, URF2" ENSG00000147854 "Ubiquitin like with PHD and ring finger domains 2" Q96PU4 9 6413151-6507054 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026633, HPA026697" Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA026633: AB_2732431, HPA026697: AB_2732432" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (8.40e-2)" "unprognostic (4.35e-3)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "unprognostic (5.69e-3)" "unprognostic (2.14e-2)" "unprognostic (6.21e-2)" "unprognostic (8.77e-2)" "unprognostic (7.42e-2)" "unprognostic (1.50e-1)" 10.0 8.1 8.2 9.9 10.3 44.6 9.7 14.9 10.4 12.9 10.4 11.6 6.2 12.9 10.0 8.3 9.9 7.9 7.2 8.7 9.2 8.1 7.9 7.8 17.3 9.4 8.6 12.4 10.7 9.7 5.4 12.1 9.4 15.3 9.2 9.2 8.5 12.6 11.0 7.7 8.5 14.0 8.8 10.4 8.3 8.4 10.0 21.2 8.1 11.9 16.6 11.4 10.1 14.3 18.1 18.8 26.7 11.9 21.4 30.7 20.5 43.9 23.4 23.7 41.2 12.4 12.0 26.9 9.2 19.2 21.8 11.9 24.6 22.5 36.0 53.6 14.9 46.3 36.2 19.7 17.8 19.3 16.1 13.5 14.1 18.4 44.5 44.4 93.2 25.4 5.1 24.0 56.0 5.9 37.0 79.2 10.8 24.8 14.8 43.1 12.4 8.7 17.2 11.3 24.8 9.4 16.6 11.0 25.6 32.1 14.0 41.9 78.6 25.2 10.0 11.0 34.4 7.2 23.2 30.4 12.4 18.2 10.2 4.0 0.5 2.7 1.2 0.5 0.8 1.8 1.8 1.0 0.3 2.9 1.0 1.2 0.5 0.6 0.9 1.2 1.9 0.6 8.2 10.3 14.9 10.4 8.7 9.2 9.4 8.6 9.4 8.8 10.0 14.3 27.5 6.4 14.4 24.2 33.9 21.5 10.2 6.2 12.0 22.0 13.8 13.1 59.0 4.3 8.4 12.9 31.3 13.2 31.3 9.1 1.9 5.2 23.6 12.8 22.9 24.1 7.1 34.9 44.2 4.0 9.9 16.0 20.9 24.5 17.7 27.8 12.8 14.6 10.7 28.6 53.3 14.8 4.1 12.6 9.3 8.1 19.3 15.6 21.4 51.5 12.5 6.4 16.5 46.8 78.6 6.2 14.4 14.7 30.1 16.0 10.2 7.3 6.3 34.8 13.1 14.4 18.8 46.2 23.4 16.1 19.0 5.9 29.0 13.7 12.6 9.8 USP12 USP12L1 ENSG00000152484 "Ubiquitin specific peptidase 12" O75317 13 27066156-27171811 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007288, HPA059492" Uncertain Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA007288: AB_1080531, HPA059492: " "unprognostic (6.72e-3)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (5.85e-2)" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "unprognostic (8.38e-2)" "unprognostic (8.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.91e-1)" "unprognostic (6.77e-2)" "unprognostic (1.73e-1)" 20.4 13.6 21.0 20.9 22.0 75.7 15.3 21.6 26.7 13.1 15.5 35.6 18.2 13.2 15.1 17.0 13.5 17.9 14.4 23.7 22.2 24.8 34.9 23.6 29.4 18.9 24.8 14.7 15.3 16.5 13.8 17.7 19.5 14.0 25.5 38.0 10.2 12.1 13.1 24.0 24.3 18.6 21.0 17.2 17.7 15.5 22.2 12.2 16.1 15.9 26.4 21.8 13.5 21.8 24.9 15.3 28.6 14.9 18.8 23.8 10.2 34.1 23.9 18.5 13.7 27.7 37.8 35.1 16.6 27.0 44.9 15.0 18.9 19.8 39.4 57.0 16.1 54.3 19.2 19.6 23.6 31.8 36.5 14.9 28.3 21.0 23.9 23.4 43.3 23.8 18.4 16.5 38.9 14.4 19.6 42.0 20.5 31.5 26.7 22.1 36.5 8.3 36.3 17.3 31.5 19.0 29.3 24.2 28.2 35.5 11.4 30.4 51.6 19.3 18.6 41.6 31.4 12.6 15.0 24.6 32.4 18.5 22.0 0.0 0.5 2.2 0.5 0.5 0.9 1.2 0.9 0.8 0.6 1.6 0.6 0.6 0.5 0.9 0.8 1.1 1.4 0.4 21.0 22.0 21.6 26.7 23.7 22.2 18.9 24.8 19.5 21.0 22.2 21.8 54.2 28.9 29.9 19.6 42.1 91.6 29.4 7.0 34.7 23.8 30.6 24.0 23.4 17.2 9.1 23.9 39.6 15.4 26.5 47.0 29.4 12.8 19.2 29.1 26.4 42.0 20.9 60.6 37.0 16.3 7.0 34.2 23.9 68.9 13.3 15.7 21.4 23.3 14.0 28.6 29.0 27.5 10.2 20.8 153.8 10.7 7.8 47.8 39.2 42.2 33.6 13.8 9.2 43.7 65.0 24.4 37.4 6.4 37.1 34.0 34.3 21.3 12.2 32.1 32.9 114.7 42.8 2.7 12.9 23.1 79.0 10.9 27.2 9.3 24.1 40.6 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 131.8;Late spermatids: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 25.2 20.3 24.2 26.5 26.3 53.7 24.9 24.5 28.2 27.7 27.1 25.4 18.3 24.4 21.6 26.0 22.4 18.3 26.5 23.7 23.4 21.8 20.2 29.5 30.9 23.9 24.4 24.5 19.0 24.1 16.4 23.3 23.9 23.7 23.4 26.9 21.0 21.7 31.6 31.4 22.5 24.0 22.4 33.7 20.2 28.0 24.8 37.0 23.0 28.8 33.7 25.8 25.0 24.5 14.2 15.8 21.6 28.8 38.7 40.1 14.7 36.4 32.9 46.7 41.3 16.8 34.8 27.1 14.4 53.9 27.4 18.9 28.6 52.6 42.5 42.1 8.4 60.3 31.9 19.6 57.0 32.5 34.0 42.8 23.3 51.0 41.5 34.3 55.0 29.9 21.6 41.6 42.1 24.5 38.3 55.8 18.7 17.7 26.9 15.6 13.3 23.9 37.5 29.2 17.5 24.0 27.2 19.3 14.0 21.6 13.5 51.2 50.1 31.1 17.2 39.6 22.5 33.6 17.3 38.6 28.6 50.1 36.5 70.1 83.6 94.8 48.1 69.2 53.7 51.0 50.2 48.9 74.6 41.4 47.7 42.2 179.2 72.4 81.2 28.4 59.7 78.0 24.2 26.3 24.5 28.2 23.7 23.4 23.9 24.4 23.9 22.4 24.8 24.5 24.3 41.7 25.1 28.1 24.7 18.7 17.9 17.2 22.2 17.5 10.9 10.3 17.9 10.0 23.2 20.2 20.9 22.7 27.9 13.6 21.5 16.5 131.8 17.3 18.3 22.1 10.7 31.6 30.8 13.6 14.3 17.9 27.5 21.1 33.6 21.4 17.5 14.6 24.0 11.8 26.4 13.8 16.2 38.6 21.0 104.9 15.5 34.2 16.0 16.9 36.0 13.9 23.7 25.6 20.2 18.9 7.6 19.2 29.2 17.6 14.5 13.4 28.6 20.5 13.1 18.4 17.0 35.3 14.5 17.9 18.5 24.2 29.4 17.0 13.9 14.5 UTP15 "FLJ12787, FLJ23637, NET21" ENSG00000164338 "UTP15 small subunit processome component" Q8TED0 5 73565443-73583380 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044697 Approved "Nucleoli,Endoplasmic reticulum" No No "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Endoplasmic reticulum" "HPA044697: AB_2679050" "unprognostic (8.96e-2)" "unprognostic (1.19e-1)" "unprognostic (1.87e-3)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (5.80e-2)" "unprognostic (1.39e-2)" "unprognostic (5.74e-2)" "unprognostic (2.12e-1)" "unprognostic (4.16e-3)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (9.66e-2)" "unprognostic (7.10e-2)" "unprognostic (1.92e-1)" "unprognostic (1.22e-1)" 8.7 6.5 2.0 8.0 2.4 36.9 9.7 3.2 3.2 4.6 1.2 6.8 5.5 7.2 6.4 9.2 5.0 5.1 4.8 2.2 2.5 5.1 7.5 5.9 10.8 2.1 2.3 4.9 7.4 7.5 3.1 6.0 2.7 5.9 8.3 5.5 4.9 4.7 7.2 9.5 5.2 7.6 1.6 7.8 5.7 6.1 2.1 7.6 8.1 7.5 10.7 9.3 4.5 3.6 21.2 22.3 15.8 44.6 12.6 14.9 27.9 24.8 14.1 27.1 29.8 25.0 29.6 47.5 24.9 16.6 34.2 17.3 25.5 45.5 41.6 23.9 19.2 21.7 23.7 20.2 15.5 20.2 18.1 15.2 20.0 30.8 34.3 8.3 19.1 21.2 33.8 25.3 23.2 26.4 31.7 14.0 20.6 7.5 12.7 24.5 24.7 45.9 16.1 28.5 15.8 16.9 22.7 17.6 27.4 13.4 22.8 14.4 15.4 15.9 22.5 19.4 49.3 19.0 27.6 60.5 26.0 34.3 23.8 4.9 6.8 4.6 8.2 7.0 7.6 7.9 8.1 9.1 7.4 7.0 9.6 9.4 5.1 8.2 7.2 7.0 7.3 4.9 2.0 2.4 3.2 3.2 2.2 2.5 2.1 2.3 2.7 1.6 2.1 3.6 8.4 0.0 7.3 2.3 7.7 14.7 13.1 5.0 11.4 3.8 6.7 6.5 6.8 4.3 5.2 5.5 6.2 8.0 6.0 2.7 3.9 8.9 4.3 4.9 6.8 6.9 2.4 9.4 6.4 7.8 9.5 8.0 5.6 6.8 7.0 6.7 2.9 8.1 6.8 1.7 5.4 4.1 2.0 5.8 2.1 2.8 3.1 3.9 7.2 1.9 3.6 3.0 2.1 3.5 6.9 6.5 3.6 5.3 9.1 10.0 2.2 6.3 1.7 4.7 6.6 9.5 8.8 10.0 12.4 11.7 17.0 6.6 6.1 7.6 6.7 9.8 UTP23 "C8orf53, MGC14595" ENSG00000147679 "UTP23 small subunit processome component" Q9BRU9 8 116766505-116849463 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044418 Uncertain Approved Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoli "HPA044418: AB_10961139" "prognostic unfavorable (5.18e-5)" "unprognostic (2.30e-2)" "unprognostic (3.34e-1)" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (7.23e-2)" "unprognostic (9.45e-3)" "unprognostic (7.73e-2)" "unprognostic (7.78e-2)" "unprognostic (1.77e-1)" "unprognostic (1.34e-2)" "unprognostic (8.62e-2)" "unprognostic (1.75e-2)" "unprognostic (5.78e-2)" "unprognostic (2.03e-1)" "unprognostic (7.15e-3)" "unprognostic (9.27e-2)" 11.8 7.9 5.6 10.1 6.6 33.2 9.6 8.1 6.7 7.8 4.3 7.1 6.2 9.6 6.5 7.2 8.1 7.9 7.1 5.7 6.0 6.8 7.4 7.8 15.4 5.6 5.5 13.7 9.7 8.1 4.8 9.6 5.7 8.1 5.6 9.6 9.0 6.4 8.6 8.0 7.8 7.4 6.1 10.3 7.7 6.8 5.4 8.2 12.3 6.2 8.9 7.9 5.9 9.0 22.0 22.7 12.9 11.3 17.9 21.3 9.8 21.9 13.3 14.1 15.6 23.8 14.2 34.4 20.5 10.5 14.1 16.1 18.2 12.8 17.4 33.5 35.3 42.5 18.3 16.2 19.1 21.2 19.7 18.6 13.8 15.7 19.1 9.2 15.4 25.9 27.7 22.6 14.1 38.3 50.2 12.4 11.8 35.9 44.1 28.1 14.2 29.7 8.9 19.8 22.7 18.3 14.2 53.8 21.5 6.5 25.8 14.6 16.4 14.7 20.3 35.7 30.9 30.8 48.9 39.7 18.8 27.4 17.4 49.7 24.6 32.6 39.5 26.6 34.2 43.1 35.2 31.2 22.1 41.6 47.7 33.2 24.6 28.1 37.0 36.1 43.6 26.4 5.6 6.6 8.1 6.7 5.7 6.0 5.6 5.5 5.7 6.1 5.4 9.0 33.6 41.7 33.1 36.2 31.0 21.9 27.0 17.4 31.9 23.2 16.7 29.2 23.4 27.1 23.4 7.3 6.2 28.3 24.8 9.9 27.4 17.3 13.9 18.0 37.0 28.7 12.0 12.4 62.6 20.7 17.9 32.9 21.9 20.6 41.8 24.3 25.0 13.8 16.6 16.8 62.2 16.6 14.2 12.6 10.5 4.8 28.9 18.5 10.6 15.9 24.0 27.4 20.6 42.3 43.0 12.4 9.4 28.6 32.0 28.7 9.0 16.2 19.2 22.4 13.1 39.5 26.4 44.0 20.3 26.6 16.2 19.8 29.5 28.8 16.6 19.1 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 4.6 3.6 3.2 6.0 3.6 20.2 4.8 4.1 5.1 3.7 1.8 4.4 3.8 3.0 4.5 3.5 2.9 3.7 2.9 4.1 4.7 4.4 7.0 4.1 8.6 4.0 3.6 3.9 4.0 5.6 1.6 4.4 4.4 3.6 4.1 4.5 4.2 3.1 5.3 3.3 3.6 3.3 3.4 8.8 4.5 5.7 5.0 5.3 4.2 5.3 7.7 4.1 2.4 4.3 8.5 7.6 3.8 5.1 11.5 8.1 3.7 6.7 6.7 5.0 5.8 4.5 7.8 11.5 1.9 9.0 6.2 7.4 6.2 5.6 7.2 8.6 4.5 12.8 7.5 5.6 6.9 4.3 13.2 8.7 8.1 5.5 9.9 6.1 5.5 6.1 8.8 10.8 7.5 4.1 9.4 7.4 7.3 7.1 5.2 5.9 6.0 5.8 7.3 6.6 2.2 4.3 5.2 7.8 6.0 4.8 8.0 7.0 11.1 6.6 4.9 5.9 4.5 9.5 5.0 11.9 6.6 6.0 5.1 10.0 2.7 5.9 3.4 4.3 2.8 1.7 2.1 2.5 2.9 2.2 1.7 2.2 9.7 2.4 8.3 1.1 2.8 1.7 3.2 3.6 4.1 5.1 4.1 4.7 4.0 3.6 4.4 3.4 5.0 4.3 18.6 19.2 15.2 9.8 18.5 17.0 9.3 10.3 12.5 11.0 12.6 9.4 20.3 11.5 12.8 7.3 22.9 10.4 38.9 18.4 3.9 10.2 7.5 16.7 17.1 14.2 6.0 23.4 17.6 13.6 5.5 15.0 15.3 16.4 19.0 12.4 17.2 22.9 14.9 11.8 18.1 15.5 8.2 47.3 20.4 5.2 8.1 25.6 10.6 14.0 28.6 11.9 39.1 13.6 21.1 13.0 16.6 15.8 21.8 14.2 14.7 12.8 18.6 12.1 6.6 21.7 20.2 32.9 16.6 16.3 20.6 9.9 28.6 11.8 13.2 16.9 VPS35 "FLJ10752, MEM3, PARK17" ENSG00000069329 "VPS35 retromer complex component" Q96QK1 16 46656132-46689518 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040802 Supported Supported Endosomes,Lysosomes NA NA 500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Endosomes, Lysosomes" "HPA040802: AB_2677142" "unprognostic (1.11e-2)" "unprognostic (8.70e-2)" "prognostic favorable (7.74e-4)" "unprognostic (4.75e-2)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "prognostic unfavorable (2.10e-6)" "unprognostic (5.32e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-2)" "unprognostic (3.33e-3)" "unprognostic (2.49e-1)" "prognostic favorable (9.75e-5)" "unprognostic (3.68e-3)" "unprognostic (2.43e-1)" "unprognostic (1.34e-1)" "unprognostic (6.89e-3)" 5.4 4.2 2.9 3.0 3.0 9.5 4.6 2.6 3.2 4.2 2.8 4.2 1.9 4.3 1.9 4.7 4.0 1.4 6.1 3.0 2.5 3.7 1.7 4.1 2.9 3.0 2.4 4.7 4.4 5.2 3.3 2.1 3.2 3.0 1.8 4.1 4.5 2.4 4.6 6.1 4.9 1.7 2.1 4.2 4.5 2.7 2.8 3.9 2.7 2.7 1.8 4.5 4.2 3.4 3.2 5.0 4.1 2.8 6.5 7.3 2.1 3.8 5.4 6.4 3.7 4.3 2.7 4.2 2.3 6.5 3.3 3.9 7.5 7.5 9.1 1.6 6.4 3.9 3.8 3.0 5.4 5.2 5.8 5.8 5.5 7.3 4.5 6.3 6.6 6.0 3.1 1.8 6.5 2.9 4.0 5.0 1.4 3.0 6.6 5.4 5.4 5.2 5.2 4.4 1.8 2.1 4.1 3.2 1.8 4.5 1.9 2.6 3.9 1.9 1.9 4.3 2.7 2.3 3.2 4.9 3.4 4.0 1.3 1.8 1.3 1.3 0.7 1.7 0.7 0.8 0.7 0.6 1.5 1.0 1.0 0.7 1.5 0.8 2.3 0.6 1.1 1.1 2.9 3.0 2.6 3.2 3.0 2.5 3.0 2.4 3.2 2.1 2.8 3.4 65.9 51.3 59.4 20.5 84.3 72.5 80.0 98.6 72.8 56.5 77.9 75.9 102.9 57.2 83.4 68.0 60.5 134.5 44.9 65.9 54.8 111.7 111.2 136.4 92.3 63.3 80.8 52.6 43.1 72.5 102.2 70.1 88.7 88.4 72.2 211.1 54.7 40.2 123.4 45.4 42.5 79.7 107.8 108.3 87.9 32.4 77.9 113.6 46.2 30.0 153.0 71.4 45.3 28.6 31.3 101.1 101.9 72.2 41.7 77.0 164.6 103.7 188.9 82.6 46.0 57.5 88.9 207.9 118.0 101.5 87.7 113.1 51.5 95.9 97.6 84.5 VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 37.1" "Cell type enhanced" "Detected in all" "Spermatocytes: 198.9;Spermatogonia: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 5.9 5.2 5.9 12.8 7.1 50.4 11.5 6.0 7.9 5.2 4.3 10.8 6.5 6.5 6.9 8.9 9.2 4.4 5.2 5.9 5.1 4.9 5.5 4.9 27.1 5.3 5.5 6.0 3.2 5.4 3.1 7.6 5.4 5.0 12.3 4.4 4.3 5.0 4.7 7.4 7.2 6.7 4.8 11.3 6.5 37.1 5.9 35.5 5.9 4.6 27.9 7.7 5.4 7.0 52.4 27.0 78.5 30.2 9.2 14.9 44.8 42.8 34.4 67.1 65.4 36.0 54.7 139.2 22.4 24.3 39.2 56.5 75.5 54.4 90.5 73.4 36.4 90.5 18.7 39.3 10.2 168.5 49.2 8.5 9.7 50.4 32.6 12.8 47.0 104.8 76.6 79.0 56.9 65.5 137.1 76.5 47.8 39.9 59.3 124.5 134.2 48.6 32.3 59.3 53.2 28.0 34.2 36.4 30.8 36.0 39.3 66.6 24.4 27.9 22.8 47.7 37.3 37.7 53.5 124.8 44.7 74.6 34.8 42.7 12.3 26.2 21.5 15.5 29.0 31.3 24.9 26.4 15.7 32.7 27.1 27.3 6.5 45.6 15.2 21.4 34.9 19.4 5.9 7.1 6.0 7.9 5.9 5.1 5.3 5.5 5.4 4.8 5.9 7.0 15.3 3.2 4.6 6.8 30.6 16.8 13.8 23.3 6.2 12.4 9.3 11.3 11.8 12.8 16.7 14.7 8.4 34.8 24.8 6.3 11.7 13.5 21.3 21.1 8.3 12.4 3.0 76.2 42.0 19.4 48.3 11.4 14.8 10.8 28.5 20.0 7.1 3.3 19.2 10.1 36.2 10.4 20.3 11.8 14.9 11.5 5.6 12.0 12.4 19.7 14.2 6.2 27.8 12.1 19.8 10.3 2.2 9.8 25.4 6.1 3.0 11.2 37.6 9.6 19.7 14.3 15.1 198.9 110.9 14.1 13.9 15.1 26.8 9.2 18.1 10.4 VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 135.2;Excitatory neurons: 244.7;Inhibitory neurons: 199.5;Late spermatids: 102.8;Microglial cells: 195.8;Oligodendrocyte precursor cells: 172.4;Oligodendrocytes: 218.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Vesicles" "HPA054108: AB_2682382" "unprognostic (9.81e-2)" "unprognostic (6.42e-2)" "unprognostic (4.49e-2)" "unprognostic (1.50e-1)" "unprognostic (1.66e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.50e-5)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic favorable (7.27e-5)" "unprognostic (3.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-3)" "unprognostic (2.61e-1)" 6.6 4.7 3.7 7.0 3.7 13.8 4.7 2.3 4.7 3.5 1.1 6.4 7.2 3.8 4.9 7.3 3.2 4.6 5.8 4.8 2.6 6.8 4.7 5.1 7.7 2.8 3.7 3.1 3.9 7.5 2.6 4.0 3.5 4.7 7.5 4.2 5.2 4.8 7.4 5.9 7.2 5.7 1.8 5.6 5.5 4.5 4.3 8.6 6.3 6.1 9.4 5.2 4.4 4.6 13.5 11.2 10.1 14.1 15.5 13.4 6.1 14.1 17.4 11.0 12.2 12.7 13.6 14.0 5.3 16.0 9.3 15.6 8.8 11.2 14.9 18.0 8.1 11.9 8.1 13.3 11.0 16.8 16.8 10.4 13.9 12.6 25.9 12.4 11.9 14.1 11.3 16.9 14.8 9.5 13.3 12.8 4.4 10.5 6.5 13.9 14.6 6.2 11.5 11.9 4.6 9.0 10.0 8.6 9.5 8.4 7.8 9.3 17.0 8.7 7.4 10.8 15.8 7.4 11.0 15.9 14.2 15.3 8.6 9.2 7.0 9.6 5.4 9.3 5.1 5.5 4.5 4.4 5.2 4.6 4.3 4.4 11.4 5.7 8.7 4.9 7.2 4.6 3.7 3.7 2.3 4.7 4.8 2.6 2.8 3.7 3.5 1.8 4.3 4.6 13.5 12.8 10.3 135.2 33.1 11.2 14.5 8.8 13.6 16.5 7.8 4.6 14.0 7.2 11.6 5.5 43.8 7.6 31.5 17.0 7.9 15.4 42.9 11.4 15.5 13.6 18.5 18.1 244.7 25.0 12.3 12.9 21.9 17.0 19.6 10.2 8.9 8.1 18.8 21.9 199.5 10.7 14.2 17.0 27.0 102.8 6.8 20.9 12.4 195.8 19.0 6.0 25.7 172.4 218.6 29.7 12.2 5.7 23.9 12.6 17.2 9.4 11.7 20.7 0.0 13.5 14.1 11.1 9.2 17.0 16.3 14.4 25.4 9.7 12.1 19.7 WASHC2C "Em:AC012044.3, FAM21C, KIAA0592" ENSG00000172661 "WASH complex subunit 2C" Q9Y4E1 10 45727200-45792964 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 35.2;Collecting duct cells: 23.9;granulocytes: 30.3;Respiratory ciliated cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (7.50e-2)" "unprognostic (2.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-2)" "unprognostic (5.98e-3)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.00e-3)" "unprognostic (1.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-2)" 19.4 15.7 10.9 17.3 11.8 42.5 17.5 14.8 14.9 19.1 13.5 20.3 15.2 16.8 12.4 13.5 14.9 16.5 22.0 11.3 11.4 18.0 15.9 17.7 20.2 12.5 12.2 21.6 11.6 21.4 13.9 13.7 12.7 15.6 22.0 14.2 15.3 14.6 17.1 17.6 19.7 19.0 9.6 19.3 15.0 12.9 14.1 21.2 17.1 9.8 18.7 17.7 14.6 14.0 24.5 25.9 20.7 23.5 52.1 45.8 12.4 28.4 45.8 32.4 30.8 16.0 23.3 20.1 18.8 41.7 30.8 21.6 23.2 13.0 32.6 18.9 19.2 20.9 32.3 12.3 55.0 21.4 24.6 43.4 30.4 35.4 26.1 31.6 33.7 16.5 33.9 15.7 40.1 12.8 14.0 35.9 14.8 14.7 3.9 17.4 30.5 10.5 23.8 38.2 10.0 22.3 32.8 16.1 39.4 21.0 22.1 20.6 58.1 16.8 18.0 44.7 19.1 21.5 36.3 19.6 23.5 49.4 9.2 14.1 17.1 11.7 12.2 17.9 11.8 9.9 10.1 12.7 11.7 9.2 10.0 8.9 16.8 12.5 22.8 8.1 10.4 13.3 10.9 11.8 14.8 14.9 11.3 11.4 12.5 12.2 12.7 9.6 14.1 14.0 16.2 35.3 35.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 11.3 8.8 0.0 0.0 11.8 23.9 0.0 6.8 11.8 0.0 3.9 13.5 0.0 11.3 17.9 6.1 0.0 0.0 0.0 14.0 6.4 7.9 0.0 13.9 30.3 13.7 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 10.3 0.0 0.0 0.0 0.0 11.9 0.0 0.0 3.8 0.0 0.0 12.8 24.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 7.8 7.0 12.1 0.0 0.0 WBP11 "BUG13, CFAP90, FAP90, NPWBP, PPP1R165, SIPP1" ENSG00000084463 "WW domain binding protein 11" Q9Y2W2 12 14784582-14803486 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA039710, HPA040037, HPA046403, HPA049126" Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA039710: AB_2676638, HPA040037: AB_10796115, HPA046403: AB_2679654, HPA049126: AB_2680644" "unprognostic (4.40e-2)" "unprognostic (1.58e-1)" "unprognostic (4.16e-2)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" "unprognostic (4.15e-2)" "prognostic unfavorable (9.40e-4)" "unprognostic (5.67e-3)" "unprognostic (3.30e-2)" "unprognostic (2.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.68e-1)" "unprognostic (2.96e-3)" "unprognostic (6.11e-2)" "unprognostic (3.07e-1)" "unprognostic (1.94e-1)" "unprognostic (4.09e-2)" 22.3 23.4 14.2 22.4 15.3 65.7 20.8 14.3 17.1 17.8 14.3 19.4 16.1 22.4 17.4 19.8 24.1 18.2 31.2 14.6 19.0 20.0 23.1 20.4 27.4 14.5 17.6 24.8 21.0 25.0 13.3 25.1 14.4 21.8 22.2 21.3 21.3 18.0 38.8 23.3 18.8 22.2 13.5 22.9 18.8 39.0 16.8 26.0 24.3 32.9 29.6 21.5 16.8 14.9 52.1 45.3 53.0 102.4 34.7 32.9 95.6 41.8 35.0 62.3 62.3 83.9 63.2 64.1 26.7 38.0 53.0 42.4 82.3 55.3 76.5 114.6 54.5 94.3 48.1 52.0 34.8 89.6 50.1 32.2 43.7 69.8 52.0 33.6 50.2 59.5 61.3 33.7 50.1 50.1 84.0 48.7 171.9 35.4 29.0 70.7 84.3 40.6 45.3 70.8 28.3 57.6 55.8 46.3 44.9 123.8 24.6 58.2 37.8 43.7 66.1 38.9 72.8 29.2 43.8 116.6 45.7 43.6 59.3 12.3 14.0 12.7 18.8 19.4 20.8 18.3 18.1 19.1 13.2 16.9 20.9 19.6 8.7 19.2 20.6 9.6 21.3 13.7 14.2 15.3 14.3 17.1 14.6 19.0 14.5 17.6 14.4 13.5 16.8 14.9 56.8 57.7 61.0 10.1 79.3 54.9 86.9 49.7 41.5 43.7 53.5 40.6 108.6 54.3 60.7 36.8 47.9 57.8 87.2 36.6 43.0 62.5 98.5 70.1 66.8 52.5 39.5 72.6 17.5 59.5 93.3 62.2 32.6 56.7 106.3 41.0 45.0 48.6 46.6 43.7 16.2 37.8 32.6 44.3 42.1 58.4 45.4 56.7 35.6 9.4 104.6 49.6 74.2 13.0 23.0 52.8 22.3 32.7 64.0 64.1 34.0 53.8 78.7 54.1 59.2 79.3 81.3 207.5 140.4 43.5 55.7 75.9 84.8 42.9 42.6 68.1 WTAP "KIAA0105, MGC3925, Mum2" ENSG00000146457 "WT1 associated protein" Q15007 6 159725585-159756319 "Predicted intracellular proteins" "Cell cycle, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 560.1;Suprabasal keratinocytes: 455.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010550 Supported Enhanced "Nuclear speckles" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA010550: AB_1858866" "unprognostic (9.57e-2)" "unprognostic (1.58e-2)" "unprognostic (5.10e-2)" "unprognostic (2.32e-1)" "unprognostic (7.19e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.57e-6)" "unprognostic (8.65e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (7.72e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (3.01e-5)" "unprognostic (7.92e-2)" "unprognostic (2.62e-1)" "unprognostic (4.00e-2)" "unprognostic (1.32e-2)" 86.2 63.7 35.3 62.3 35.7 245.1 74.9 40.0 41.3 71.7 41.3 54.6 34.9 64.7 65.1 65.0 64.2 52.2 54.3 35.0 42.5 54.8 50.7 68.6 77.5 38.2 38.3 70.5 63.3 53.2 49.8 61.8 39.4 65.1 55.2 35.6 62.0 44.6 179.7 72.5 61.6 51.5 36.9 67.0 58.5 34.9 40.1 89.7 57.4 67.4 80.7 102.6 65.1 41.2 55.5 51.1 115.8 100.2 136.5 147.7 67.1 86.2 299.4 108.7 145.4 95.7 49.0 126.8 50.8 92.6 238.4 70.4 112.2 94.3 138.1 70.0 71.9 135.0 46.7 144.2 108.4 116.1 75.4 172.0 94.7 120.0 155.0 82.6 81.6 130.7 149.1 114.2 116.0 53.5 170.5 165.0 91.9 88.6 44.2 107.4 74.3 94.4 114.0 62.6 104.5 74.5 158.2 83.5 45.7 77.5 41.3 152.6 72.6 70.0 81.4 100.1 125.0 83.9 109.6 206.5 67.8 120.9 76.8 46.6 24.5 31.0 28.1 31.7 31.7 33.1 33.9 34.3 29.1 27.5 29.9 31.4 42.9 32.1 38.3 24.3 40.2 20.2 35.3 35.7 40.0 41.3 35.0 42.5 38.2 38.3 39.4 36.9 40.1 41.2 131.1 35.3 57.3 31.3 138.1 419.0 198.0 52.9 113.8 30.0 144.2 123.6 58.1 74.4 39.9 60.7 35.5 107.3 138.5 61.2 86.1 128.1 47.1 86.4 125.5 118.8 61.6 59.3 41.5 81.4 126.7 226.9 97.9 171.9 40.0 56.7 58.2 90.5 75.4 37.0 36.6 65.7 24.4 99.7 560.1 50.7 65.3 168.6 243.7 33.7 113.7 49.7 88.6 44.7 57.0 75.8 59.7 50.8 111.5 307.5 49.6 106.5 35.3 36.2 72.3 222.2 124.5 93.8 73.9 113.0 455.3 149.3 138.6 54.7 74.0 150.9 XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;intestine: 12.2;stomach 1: 11.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.7;Erythroid cells: 63.5;Gastric mucus-secreting cells: 17.9;Proximal enterocytes: 21.5;Undifferentiated cells: 14.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 102 "granulocytes: 10.2" "Cell line enhanced" "Detected in many" "HEL: 44.4;HL-60: 23.2;K-562: 29.1;NB-4: 21.1;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" 0.2 2.1 2.5 1.4 2.5 14.2 0.7 2.3 3.0 1.2 0.2 12.2 10.8 0.7 0.5 2.0 3.8 0.9 4.3 3.2 4.9 0.9 0.8 1.0 0.2 1.6 0.9 0.7 4.9 0.7 1.3 0.7 2.0 1.5 11.2 2.1 1.2 0.9 5.4 0.7 10.6 1.8 0.5 0.5 11.5 1.4 2.8 0.2 0.9 5.8 0.5 1.1 0.8 1.4 17.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 14.7 0.3 0.0 0.8 2.7 15.4 0.1 0.0 0.0 4.2 44.4 2.4 0.0 0.0 23.2 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 29.1 10.9 0.1 1.7 0.2 21.1 5.5 0.7 5.6 0.0 0.0 20.2 0.0 1.1 4.1 0.1 0.8 1.4 0.1 0.9 2.1 5.6 0.0 0.0 0.8 0.0 2.4 9.3 16.5 0.0 0.2 12.1 0.1 10.2 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 2.5 2.5 2.3 3.0 3.2 4.9 1.6 0.9 2.0 0.5 2.8 1.4 0.0 0.0 1.1 2.6 0.8 0.4 0.4 0.1 1.2 0.7 1.1 0.8 7.9 0.0 0.1 0.0 6.2 0.3 0.1 26.7 0.0 0.0 1.2 4.0 0.1 0.3 6.1 63.5 11.0 3.1 0.1 0.6 17.9 0.9 0.0 0.1 0.0 0.9 0.1 3.3 12.6 10.9 2.0 0.3 0.0 0.4 0.0 0.2 1.8 1.9 0.0 0.0 0.0 4.5 1.2 1.1 9.2 0.7 2.2 0.9 21.5 0.1 1.7 1.4 0.0 0.7 1.3 10.2 6.1 3.8 1.1 0.0 0.3 0.1 14.7 1.5 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA062422: AB_2684757, HPA068953: AB_2686062" "unprognostic (2.52e-2)" "unprognostic (1.81e-3)" "unprognostic (6.75e-2)" "unprognostic (4.01e-2)" "unprognostic (4.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-4)" "unprognostic (2.93e-2)" "unprognostic (4.67e-2)" "unprognostic (1.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.53e-2)" "unprognostic (3.52e-7)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (8.84e-2)" "unprognostic (3.72e-2)" 9.8 6.0 8.7 8.7 12.5 31.9 9.3 7.2 10.3 13.7 11.9 11.1 6.9 10.4 1.7 13.9 10.9 6.6 8.3 6.6 5.8 7.9 7.7 12.1 15.4 13.6 9.7 12.7 9.8 1.7 8.6 5.2 9.7 13.4 7.5 4.5 12.7 3.3 12.4 39.0 12.6 2.8 7.7 21.3 9.1 13.8 9.7 10.0 10.5 2.5 11.0 9.6 12.4 14.3 32.4 58.4 31.5 38.5 2.8 7.9 57.0 35.5 11.6 48.9 52.3 32.4 50.3 51.8 29.5 7.5 38.4 50.3 34.6 52.4 29.9 31.3 36.1 50.6 31.6 30.4 4.9 45.3 30.8 6.0 5.2 43.2 26.7 10.4 20.2 51.3 31.8 30.4 25.2 70.7 79.6 35.8 26.4 47.1 42.0 63.7 45.7 19.8 10.5 44.2 31.1 25.7 41.3 21.7 14.3 17.4 34.6 35.0 17.5 25.1 28.9 80.0 38.8 26.2 25.8 63.7 15.6 36.9 38.4 0.7 0.5 0.9 1.0 0.9 1.0 1.1 0.8 0.8 0.5 0.9 0.8 0.5 0.3 0.7 0.7 0.4 0.6 1.3 8.7 12.5 7.2 10.3 6.6 5.8 13.6 9.7 9.7 7.7 9.7 14.3 2.2 0.0 0.0 2.6 2.5 1.5 1.9 2.1 1.8 1.7 3.2 3.6 0.2 2.8 2.5 0.0 2.1 10.2 1.8 6.9 1.9 1.5 0.7 1.9 2.2 2.0 1.2 7.4 2.6 1.8 6.1 1.2 0.5 2.0 0.0 4.7 0.4 0.3 4.4 3.3 1.0 7.4 0.0 0.0 2.0 1.8 0.3 1.5 0.0 1.0 1.5 1.7 2.1 1.5 1.4 1.7 2.6 1.2 4.4 1.6 0.7 0.2 1.7 2.3 0.0 2.6 1.2 3.1 5.8 2.8 1.3 3.1 2.0 4.2 8.3 1.2 YEATS4 "GAS41, NuBI-1, YAF9" ENSG00000127337 "YEATS domain containing 4" O95619 12 69359710-69390870 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Spermatocytes: 364.9;Spermatogonia: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072532 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane" "HPA072532: AB_2686530" "unprognostic (7.23e-2)" "unprognostic (8.50e-3)" "unprognostic (2.05e-3)" "unprognostic (8.07e-3)" "unprognostic (1.64e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.77e-2)" "unprognostic (3.03e-3)" "unprognostic (1.80e-2)" "unprognostic (6.15e-2)" "unprognostic (2.13e-1)" "unprognostic (7.19e-2)" "unprognostic (8.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" 9.4 11.8 5.6 10.4 6.1 45.8 17.8 9.4 8.2 10.1 9.5 12.3 13.3 10.3 14.9 11.6 12.2 8.3 11.1 6.1 6.2 15.3 14.9 8.9 22.5 6.2 5.9 9.9 17.3 11.1 10.1 10.9 6.3 10.8 13.7 20.1 12.0 9.6 14.3 11.3 13.6 8.4 6.4 10.9 11.0 37.1 5.9 25.9 13.8 19.5 20.4 11.3 9.5 8.0 54.3 27.0 52.1 32.5 11.8 18.9 41.3 32.0 33.7 54.7 45.6 31.1 15.4 108.1 30.5 17.3 28.2 40.8 41.6 32.3 53.2 54.2 45.4 63.0 20.5 37.6 16.5 92.4 53.3 14.0 40.3 29.1 43.1 27.9 31.7 90.1 53.4 127.9 26.8 27.5 130.4 99.8 72.5 36.0 37.6 68.9 49.0 53.6 30.9 47.7 57.6 39.4 33.0 31.4 54.9 32.2 60.5 52.9 18.9 22.5 22.9 63.4 39.4 34.2 44.5 120.2 24.4 43.7 40.1 9.3 13.1 26.4 21.1 19.2 24.0 22.7 29.5 22.2 17.9 21.2 34.8 30.3 6.0 21.6 28.4 14.9 31.8 21.2 5.6 6.1 9.4 8.2 6.1 6.2 6.2 5.9 6.3 6.4 5.9 8.0 14.5 6.4 25.8 11.4 29.0 29.7 36.1 36.3 17.6 25.5 29.5 25.7 23.4 14.3 24.4 11.0 12.5 51.2 24.9 16.8 46.9 31.4 8.0 27.2 10.6 16.3 17.6 50.9 13.6 38.9 58.0 17.4 13.3 19.9 19.0 21.8 12.5 17.0 37.6 18.5 15.5 26.4 22.4 15.1 24.3 14.6 18.6 19.8 12.4 6.5 44.1 26.5 20.6 10.1 18.4 33.2 17.3 24.0 18.3 37.0 23.7 35.2 26.1 28.2 19.7 26.4 18.6 364.9 109.1 26.5 32.0 23.5 33.0 30.7 34.3 34.9 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.6" "Cell type enhanced" "Detected in all" "Erythroid cells: 70.9;Glandular and luminal cells: 118.8;Late spermatids: 103.3;Urothelial cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 86.3;K-562: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 3.0 4.5 3.5 4.3 3.8 58.6 5.4 3.7 5.5 5.2 3.9 3.9 4.2 3.7 2.9 24.6 2.6 2.8 4.4 4.0 3.4 4.7 5.4 8.5 4.7 5.5 3.6 2.9 3.2 1.6 2.7 5.7 4.4 3.0 3.9 7.6 6.6 2.7 4.8 15.6 4.8 2.5 3.6 5.7 8.8 3.8 5.0 9.9 5.3 4.1 7.6 4.6 10.9 9.9 11.8 6.1 9.5 5.7 3.3 4.4 18.5 7.6 5.9 5.7 5.7 11.7 11.9 6.1 3.0 4.7 2.7 12.6 0.1 9.3 6.4 4.9 10.3 86.3 27.6 5.6 3.1 11.5 29.2 3.1 7.1 4.6 17.7 6.7 5.0 12.5 61.1 0.0 5.0 0.1 10.1 6.3 9.1 4.9 13.5 5.1 0.4 4.5 5.7 13.0 5.0 11.0 12.5 14.4 16.7 8.4 5.1 8.1 2.4 4.8 12.6 4.0 10.0 9.5 0.6 9.0 5.7 0.0 3.3 1.0 0.3 0.5 0.2 0.3 0.3 0.0 0.3 0.2 0.3 0.1 0.3 0.4 0.7 0.3 0.2 0.1 0.2 0.2 3.5 3.8 3.7 5.5 4.0 3.4 5.5 3.6 4.4 3.6 5.0 9.9 6.8 41.7 12.2 20.5 3.3 31.6 29.4 8.1 21.1 8.0 6.2 3.8 7.0 2.8 10.0 1.8 4.2 2.7 8.2 39.4 1.9 4.1 35.4 50.5 19.0 6.7 8.9 70.9 8.5 10.5 3.2 5.5 36.2 118.8 8.2 6.1 2.9 8.6 2.8 11.8 6.4 5.0 12.2 10.0 12.5 103.3 1.5 8.3 14.2 6.5 5.2 4.9 6.2 6.0 16.4 24.4 67.8 2.2 4.8 38.2 7.8 7.0 21.6 17.9 6.6 3.6 6.0 10.9 4.6 33.9 40.2 1.8 6.9 9.0 7.5 86.5 YTHDC1 "KIAA1966, YT521, YT521-B" ENSG00000083896 "YTH domain containing 1" Q96MU7 4 68310387-68350090 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036462 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane" "HPA036462: AB_10669793" "unprognostic (1.02e-1)" "unprognostic (8.44e-3)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-3)" "unprognostic (8.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.63e-2)" "unprognostic (1.70e-1)" "unprognostic (4.05e-1)" "prognostic favorable (7.29e-5)" 43.0 27.0 22.4 19.5 26.5 116.6 43.8 31.9 25.0 52.6 18.6 40.0 15.6 43.6 22.7 48.0 42.3 15.3 34.1 20.9 26.0 38.2 33.1 40.6 28.4 23.6 23.6 68.6 44.5 20.3 41.2 23.8 24.8 37.9 19.6 38.5 42.1 17.6 47.2 51.3 40.5 17.2 23.2 41.9 36.3 31.3 23.1 30.3 42.1 16.7 26.7 37.3 50.5 32.7 31.8 18.4 37.1 22.2 21.7 18.8 30.4 33.8 21.3 20.6 21.5 22.9 27.9 50.8 27.0 17.2 16.7 23.3 35.1 29.4 33.1 38.2 21.3 38.8 27.3 25.6 22.1 41.5 29.0 17.8 31.3 18.5 44.0 26.6 22.6 24.7 37.5 29.0 30.7 23.9 48.9 37.1 27.6 30.4 18.0 42.4 41.6 22.8 32.6 35.6 31.9 24.8 29.5 31.5 25.9 34.3 24.6 28.8 24.1 23.5 24.9 16.4 22.5 30.1 21.8 53.7 15.9 26.6 22.0 69.3 20.3 40.4 24.1 12.7 19.0 36.1 19.6 19.8 12.2 44.8 26.9 22.9 105.4 20.8 27.0 39.3 20.3 9.7 22.4 26.5 31.9 25.0 20.9 26.0 23.6 23.6 24.8 23.2 23.1 32.7 104.6 112.2 129.5 54.9 104.7 119.9 103.6 76.2 88.8 105.8 112.8 107.2 92.6 85.8 125.1 73.5 70.9 73.6 136.8 58.1 52.8 70.2 98.5 131.9 135.3 92.2 85.8 74.7 43.8 57.2 124.8 81.3 54.0 254.8 94.7 86.2 63.5 85.6 43.2 90.9 49.4 77.9 63.1 61.0 75.9 22.0 74.6 84.5 64.0 56.2 67.0 99.2 96.8 59.3 110.1 81.6 56.0 67.7 103.2 121.6 42.0 44.0 113.2 138.4 52.6 122.0 98.8 139.2 95.9 127.1 134.5 119.0 122.0 59.5 66.9 119.8 YTHDF2 "CAHL, HGRG8, NY-REN-2" ENSG00000198492 "YTH N6-methyladenosine RNA binding protein 2" Q9Y5A9 1 28736621-28769775 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Immunity, Innate immunity, Mitosis, Oogenesis, Spermatogenesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030063, HPA054080, HPA059621" Approved Enhanced "Cytosol,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Cytoplasmic bodies" "HPA030063: AB_2732453, HPA054080: AB_2682371, HPA059621: AB_2684084" "unprognostic (8.75e-2)" "unprognostic (1.90e-2)" "unprognostic (4.66e-3)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.14e-9)" "unprognostic (1.75e-2)" "unprognostic (4.82e-2)" "unprognostic (4.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.11e-2)" "unprognostic (2.07e-1)" "unprognostic (1.21e-1)" "unprognostic (6.38e-2)" "unprognostic (9.29e-2)" "unprognostic (6.97e-3)" 33.5 33.0 20.0 26.7 21.0 63.9 38.3 22.1 24.8 27.5 29.5 32.0 29.4 27.8 43.6 37.5 27.7 27.0 27.0 21.3 22.5 31.8 42.2 35.6 35.6 20.2 19.6 29.3 27.4 37.1 18.0 34.4 20.6 22.9 33.8 20.2 39.8 23.9 43.9 41.9 26.2 32.9 21.4 32.1 27.6 29.3 21.2 44.1 28.0 33.7 43.8 32.8 26.1 23.1 68.8 46.3 99.6 96.8 75.5 58.1 117.8 66.1 80.7 80.0 80.4 42.8 78.1 117.8 64.4 84.4 47.8 62.2 117.3 105.7 94.0 76.0 91.9 98.7 60.7 78.4 90.0 105.1 74.4 78.5 106.4 86.1 121.1 70.0 99.0 70.0 101.9 55.6 89.7 53.3 112.1 80.8 161.8 61.1 61.1 95.4 74.2 96.8 111.3 95.8 85.7 91.2 68.6 102.1 181.7 82.6 67.8 95.8 69.4 55.4 57.8 52.5 93.5 68.2 47.7 133.3 63.3 81.2 89.9 108.3 78.4 78.7 66.1 91.1 88.3 80.3 72.7 80.3 96.7 59.0 77.9 73.2 26.5 92.4 94.4 62.6 92.3 109.5 20.0 21.0 22.1 24.8 21.3 22.5 20.2 19.6 20.6 21.4 21.2 23.1 70.8 51.3 61.2 13.7 70.8 152.7 104.9 111.0 109.8 45.4 110.2 101.3 52.8 77.2 85.3 44.1 31.3 149.6 79.5 46.4 66.5 102.0 16.3 65.8 78.2 78.5 75.7 52.8 22.5 69.6 108.3 64.5 49.5 76.6 72.3 63.6 77.4 102.3 77.3 58.9 20.4 76.0 105.8 65.4 75.4 19.3 71.1 56.7 37.4 21.5 74.1 66.4 73.2 14.1 23.5 80.7 43.8 75.2 71.0 78.6 42.4 96.0 53.8 45.9 92.1 61.5 83.0 142.2 115.5 95.3 161.7 260.2 69.2 69.5 65.9 118.7 YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "CAB009392: AB_2218501, HPA001119: AB_1858930" "unprognostic (7.67e-2)" "unprognostic (8.08e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (6.75e-3)" "unprognostic (8.31e-3)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.09e-1)" "unprognostic (4.26e-2)" "unprognostic (7.68e-3)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" 27.2 26.2 20.9 28.9 22.1 56.4 27.0 27.0 24.2 24.6 18.5 30.7 27.9 24.8 34.0 28.9 21.7 22.7 22.8 22.7 20.2 32.9 46.8 24.0 36.0 20.4 20.4 21.6 24.4 32.5 17.4 34.2 20.3 25.2 28.7 20.1 25.1 23.6 36.8 29.0 29.7 24.8 20.1 31.9 26.2 23.8 21.5 52.3 37.2 27.2 38.2 31.9 21.0 26.2 62.0 30.7 64.2 51.5 51.8 65.9 68.1 60.0 55.1 64.7 66.0 38.6 97.7 94.0 82.3 54.5 37.1 64.0 72.6 64.1 88.3 70.8 60.9 86.8 34.6 50.0 48.4 103.8 73.2 38.7 76.4 45.4 61.4 58.6 63.9 67.3 69.9 61.8 63.7 74.5 113.5 61.8 68.7 98.0 56.0 93.9 88.9 50.7 75.8 58.3 68.2 53.3 79.2 57.8 85.1 54.0 86.6 100.1 57.4 39.4 48.3 97.6 53.8 68.3 72.0 126.6 56.4 68.6 52.5 4.8 5.7 11.9 4.3 4.8 5.6 5.3 5.7 5.9 4.9 8.3 5.4 5.4 9.8 9.5 3.8 5.3 7.7 2.7 20.9 22.1 27.0 24.2 22.7 20.2 20.4 20.4 20.3 20.1 21.5 26.2 116.0 54.5 66.8 23.8 102.4 238.0 101.1 49.9 211.7 80.5 129.8 98.2 91.5 92.9 50.0 68.0 81.3 118.6 147.4 122.8 72.4 68.7 10.3 118.7 133.8 115.7 110.1 125.4 28.2 82.0 123.6 106.7 58.1 153.6 71.7 99.4 103.5 119.4 81.3 127.9 26.5 108.8 48.8 111.8 225.8 15.7 94.8 121.6 76.5 30.0 117.8 82.0 114.4 20.6 40.7 80.0 95.5 100.8 125.0 168.9 90.0 104.6 47.6 74.9 92.1 106.5 124.3 86.0 67.0 192.1 243.1 175.5 124.8 124.1 118.7 153.5 ZBTB1 "KIAA0997, ZNF909" ENSG00000126804 "Zinc finger and BTB domain containing 1" Q9Y2K1 14 64503712-64533690 "Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA repair, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050516, HPA054552, HPA075151" Approved Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA050516: AB_2681153, HPA054552: , HPA075151: " "unprognostic (4.09e-1)" "unprognostic (3.68e-1)" "unprognostic (1.08e-1)" "unprognostic (9.51e-2)" "unprognostic (1.28e-1)" "prognostic favorable (4.92e-4)" "unprognostic (1.11e-3)" "unprognostic (9.43e-2)" "unprognostic (6.64e-2)" "unprognostic (2.00e-1)" "unprognostic (9.65e-2)" "unprognostic (6.63e-2)" "unprognostic (3.34e-2)" "unprognostic (6.26e-2)" "unprognostic (2.23e-1)" "unprognostic (2.58e-1)" "unprognostic (3.27e-2)" 24.0 15.2 14.2 28.9 17.1 83.1 25.8 15.8 16.6 21.1 17.8 21.4 16.9 20.5 26.9 15.9 24.8 21.2 16.9 15.0 14.2 17.9 22.1 22.3 44.1 16.5 15.6 21.5 17.8 20.8 18.0 24.0 16.8 24.2 22.2 20.8 18.5 17.9 22.6 34.7 23.9 19.3 16.3 34.8 21.0 12.4 17.7 38.5 27.9 21.3 35.8 21.9 20.2 19.8 56.2 18.4 40.5 25.4 41.1 49.3 41.5 23.8 35.4 22.0 27.9 17.9 38.7 53.5 23.2 33.8 17.2 38.4 19.9 23.6 30.0 79.7 13.5 26.1 35.9 15.1 25.8 21.9 36.7 63.7 40.6 15.3 22.6 48.3 25.8 33.8 13.1 35.7 41.2 42.5 38.0 22.0 16.9 28.8 27.5 33.7 25.0 20.7 38.3 67.1 28.2 22.6 38.9 29.0 32.7 39.0 27.9 27.9 34.4 36.6 24.7 17.7 16.7 44.6 20.6 59.6 36.9 20.6 24.5 42.5 13.6 23.1 18.8 13.1 21.4 14.8 16.6 20.9 14.6 14.3 16.8 20.8 10.4 19.9 19.1 9.1 25.6 16.4 14.2 17.1 15.8 16.6 15.0 14.2 16.5 15.6 16.8 16.3 17.7 19.8 19.8 16.0 12.7 65.6 56.9 31.7 17.0 29.7 40.9 11.5 14.4 13.7 11.9 8.6 22.3 9.2 12.5 8.0 115.7 9.2 9.8 13.2 83.0 40.0 41.5 24.7 22.1 20.8 40.6 8.6 13.7 26.5 19.9 30.2 28.5 18.8 19.2 8.4 15.2 6.7 58.1 12.1 30.5 23.0 73.5 38.0 15.8 50.5 30.2 58.1 13.8 7.7 22.6 40.2 96.3 16.2 8.3 18.4 48.3 15.2 6.0 6.6 27.8 8.4 6.6 20.4 27.9 2.2 4.5 23.7 24.2 7.8 78.7 23.5 10.9 19.2 ZBTB11 "ZNF-U69274, ZNF913" ENSG00000066422 "Zinc finger and BTB domain containing 11" O95625 3 101648889-101677132 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015328, HPA024138" Approved Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA015328: AB_1858938, HPA024138: AB_1858939" "unprognostic (3.25e-3)" "unprognostic (9.62e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (2.86e-2)" "unprognostic (7.04e-2)" "unprognostic (1.17e-3)" "unprognostic (4.77e-1)" "unprognostic (6.65e-3)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (1.45e-2)" "unprognostic (5.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.89e-1)" "unprognostic (5.90e-2)" "unprognostic (2.09e-1)" 7.3 7.2 6.1 10.6 7.0 38.0 10.0 11.8 10.3 8.2 5.9 6.7 8.3 9.8 7.2 7.6 6.8 7.4 5.6 6.9 5.9 7.3 9.6 8.2 13.5 5.6 6.0 10.4 9.6 9.9 5.5 9.2 6.2 8.1 7.6 12.4 9.2 6.7 9.1 12.4 7.2 7.1 6.6 13.1 7.8 10.5 6.3 13.7 8.4 10.0 12.7 8.6 6.8 10.0 14.8 16.5 10.7 14.0 16.7 16.3 18.7 14.4 14.2 13.0 14.3 15.0 10.0 18.1 11.4 11.0 11.6 18.0 16.3 16.4 23.3 18.8 11.3 40.1 15.8 14.1 12.8 28.8 14.2 13.1 20.8 12.1 27.8 11.6 13.0 20.6 23.7 21.2 14.1 18.4 25.5 12.8 10.1 15.7 24.0 20.6 16.7 22.1 12.2 17.4 31.0 11.4 18.7 15.0 19.1 6.5 19.1 15.3 14.7 19.6 14.2 8.2 14.5 24.2 21.7 33.4 12.2 18.6 13.9 6.7 3.7 4.2 3.6 4.6 4.7 2.9 3.1 4.0 4.6 3.8 3.5 3.0 2.4 3.0 7.3 2.7 3.8 2.8 6.1 7.0 11.8 10.3 6.9 5.9 5.6 6.0 6.2 6.6 6.3 10.0 19.0 32.1 20.8 12.7 28.2 46.4 20.0 8.4 51.8 14.2 21.4 17.4 12.1 10.0 19.3 1.8 33.3 10.2 40.3 14.0 0.0 6.6 3.2 44.7 50.4 20.1 20.2 12.4 32.7 5.5 7.5 19.4 15.8 70.2 8.8 13.7 13.2 10.3 7.9 21.9 28.2 14.5 14.2 23.0 24.4 3.9 8.4 25.9 19.6 12.2 20.3 12.0 21.6 15.1 27.6 7.6 4.4 14.3 32.6 18.3 8.2 6.2 20.1 22.8 6.6 25.0 19.1 25.5 21.8 50.0 49.0 16.8 34.1 14.3 14.2 24.1 ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: AB_1079167, HPA005732: AB_1079166" "unprognostic (9.14e-3)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.47e-2)" "unprognostic (6.13e-2)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.51e-2)" "unprognostic (5.08e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (6.44e-2)" "unprognostic (2.59e-2)" 6.4 7.0 6.4 8.5 7.0 19.5 15.4 7.1 9.0 6.8 4.7 6.8 7.7 6.2 9.4 9.9 8.2 7.3 4.9 6.4 9.2 6.4 19.0 8.7 13.2 7.3 8.7 9.7 8.4 13.7 4.8 8.8 8.5 7.4 6.5 5.7 10.4 6.0 5.4 18.8 6.4 4.8 8.4 11.5 8.6 5.7 9.3 16.2 10.2 7.7 12.8 8.0 4.8 9.7 13.6 12.9 19.6 18.1 15.9 17.8 23.4 10.3 13.5 11.7 14.5 9.0 11.7 19.5 18.8 10.4 15.7 20.7 31.9 15.7 15.3 22.0 21.6 20.3 20.3 12.7 11.6 21.2 22.7 12.7 19.9 11.2 17.6 17.1 20.9 18.7 13.5 23.2 14.6 15.6 19.2 14.1 24.3 20.9 15.3 21.9 14.9 32.0 12.5 22.2 35.6 15.2 20.9 21.3 25.3 14.9 11.5 29.6 19.6 9.5 6.9 14.3 18.5 12.7 13.1 24.7 12.6 29.4 11.9 11.5 4.2 5.6 2.9 6.4 5.0 2.4 3.8 3.9 6.2 2.2 4.6 3.4 0.9 4.0 4.2 6.7 3.5 3.6 6.4 7.0 7.1 9.0 6.4 9.2 7.3 8.7 8.5 8.4 9.3 9.7 15.7 16.0 7.0 3.9 7.9 12.7 7.8 5.1 12.5 4.5 11.5 13.1 5.2 8.6 11.9 1.8 0.0 7.7 21.7 5.3 1.9 5.5 0.1 12.9 8.7 8.5 8.4 10.3 3.4 6.7 8.7 7.9 7.1 10.3 0.0 16.0 7.9 16.6 7.6 3.3 4.6 7.0 6.1 12.8 10.3 0.4 4.4 8.2 3.6 3.7 14.6 7.0 14.4 5.0 4.6 6.9 5.7 2.6 5.4 9.5 6.8 4.0 15.3 1.6 6.6 6.9 4.1 5.0 10.0 12.7 13.1 9.3 8.7 11.2 6.0 11.9 ZC3H12A "FLJ23231, MCPIP1, Regnase-1" ENSG00000163874 "Zinc finger CCCH-type containing 12A" Q5D1E8 1 37474580-37484377 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Antiviral defense, Apoptosis, Differentiation, DNA damage, Host-virus interaction, Immunity, Inflammatory response, Neurogenesis, Stress response, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 136.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 300.7;Basal squamous epithelial cells: 242.4;Langerhans cells: 232.8;Squamous epithelial cells: 217.6;Suprabasal keratinocytes: 225.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 48.8;RT4: 61.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA032052, HPA032053" Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" No No "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Cytoplasmic bodies" Nucleoplasm "HPA032052: AB_10603241, HPA032053: AB_2674128" "unprognostic (2.35e-2)" "unprognostic (6.09e-3)" "unprognostic (1.51e-2)" "prognostic favorable (9.67e-4)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (9.03e-2)" "unprognostic (4.66e-3)" "unprognostic (1.05e-1)" "unprognostic (9.69e-3)" "unprognostic (9.01e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (5.17e-2)" "unprognostic (4.69e-2)" "unprognostic (1.68e-1)" "unprognostic (3.77e-2)" 28.9 28.0 2.4 17.3 2.3 136.3 15.1 3.6 4.1 9.1 2.7 16.3 14.1 6.6 4.6 45.4 14.3 36.0 12.1 2.5 3.8 15.7 23.3 40.0 13.6 4.1 3.7 6.0 12.4 2.5 9.2 3.7 4.1 29.5 7.9 0.3 22.9 5.2 10.8 51.5 20.1 5.7 3.0 15.5 23.5 5.2 3.7 5.7 6.5 3.2 15.5 39.0 21.4 2.8 7.8 5.5 0.6 3.5 2.7 4.0 6.2 5.5 48.8 3.5 4.5 6.1 17.2 8.7 22.8 5.3 37.8 16.8 2.2 35.4 2.0 17.8 3.2 2.3 20.9 9.7 3.9 4.6 3.5 8.6 17.8 30.0 5.3 7.9 3.9 4.4 4.3 14.1 3.1 9.4 3.5 8.3 4.2 10.4 4.8 5.2 2.2 5.1 8.8 61.2 1.6 1.1 11.0 17.4 1.3 5.3 6.0 5.1 4.1 10.3 5.7 7.7 8.5 11.2 4.5 6.6 23.5 9.7 2.0 1.2 1.4 4.0 3.1 1.4 3.3 3.1 1.3 1.9 1.7 3.9 0.7 1.5 5.6 3.5 1.2 1.5 2.0 1.7 2.4 2.3 3.6 4.1 2.5 3.8 4.1 3.7 4.1 3.0 3.7 2.8 19.1 16.0 36.2 1.6 56.9 195.9 149.8 300.7 242.4 0.4 93.6 69.8 4.2 61.5 117.6 11.0 0.0 3.7 78.1 71.5 0.0 79.5 16.9 67.6 20.8 32.2 63.9 0.4 0.1 73.9 10.0 41.0 66.3 102.2 42.6 5.0 5.3 11.4 9.7 0.0 0.1 77.3 69.2 10.5 232.8 2.7 0.9 71.2 48.0 1.0 14.0 0.9 9.2 0.5 0.9 55.4 73.2 1.2 52.1 127.9 59.5 0.6 58.4 4.5 6.6 52.7 36.1 1.6 1.3 217.6 225.2 11.8 76.6 9.5 62.2 81.9 ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031099: AB_10599418, HPA031100: AB_2257403, HPA031101: AB_10611669" "unprognostic (1.51e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.24e-1)" "unprognostic (3.11e-3)" "unprognostic (5.92e-2)" "unprognostic (8.15e-2)" "prognostic unfavorable (1.48e-7)" "unprognostic (9.08e-3)" "unprognostic (4.95e-2)" "prognostic favorable (3.98e-4)" "prognostic unfavorable (9.75e-4)" "unprognostic (5.72e-3)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.82e-1)" "unprognostic (8.89e-2)" "unprognostic (3.45e-2)" 42.6 47.5 39.2 44.3 42.0 128.8 45.9 43.4 52.5 35.1 38.6 40.8 48.3 39.8 47.0 40.2 26.3 36.5 37.0 42.6 44.5 53.8 67.3 28.4 53.9 42.2 40.9 32.6 47.9 41.2 27.2 48.8 41.7 37.0 46.0 53.0 45.3 32.4 50.3 44.3 46.1 36.9 39.4 38.6 36.8 40.6 41.7 50.2 49.3 44.9 51.4 54.0 29.2 42.4 103.5 68.9 83.3 107.8 93.0 93.4 124.9 112.7 76.7 102.3 91.5 202.9 81.8 140.3 100.2 80.9 130.9 73.6 155.8 137.5 144.0 128.7 118.1 201.9 101.1 221.9 124.9 208.7 118.6 77.2 149.6 111.4 157.2 89.9 111.9 86.0 197.0 106.8 108.4 93.5 133.7 146.5 157.6 135.7 171.8 105.2 113.0 131.6 127.6 124.0 100.3 73.6 71.5 96.4 167.3 124.3 68.1 149.7 95.7 114.7 99.1 70.9 136.4 92.0 167.0 199.8 101.7 145.7 102.3 59.9 47.9 49.1 44.7 61.6 55.8 55.0 54.8 57.4 54.7 42.2 50.5 53.9 28.8 60.4 75.1 48.0 66.6 41.5 39.2 42.0 43.4 52.5 42.6 44.5 42.2 40.9 41.7 39.4 41.7 42.4 107.1 73.7 83.6 26.4 137.0 212.2 169.1 116.6 99.6 75.0 101.9 118.9 95.8 57.2 104.8 115.8 60.5 131.3 116.1 131.4 256.3 112.0 153.1 110.1 125.5 106.4 101.7 98.7 38.0 104.3 167.0 107.4 67.8 127.1 112.2 220.1 62.4 137.0 124.3 57.2 39.8 136.1 87.5 107.4 104.8 307.1 78.6 113.2 64.0 33.7 142.5 82.6 126.7 19.6 32.8 111.6 106.2 87.3 128.0 179.5 164.1 330.2 68.3 130.2 32.9 156.2 127.6 215.6 174.4 116.1 209.1 177.6 117.3 319.6 151.2 163.5 ZCCHC10 FLJ20094 ENSG00000155329 "Zinc finger CCHC-type containing 10" Q8TBK6 5 132996985-133026604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038944 Approved Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim" Nucleoplasm "HPA038944: AB_10673601" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-2)" "unprognostic (2.30e-2)" "unprognostic (4.77e-1)" "unprognostic (1.90e-3)" "unprognostic (1.23e-3)" "unprognostic (8.80e-2)" "unprognostic (1.89e-3)" "unprognostic (1.69e-1)" "unprognostic (2.03e-1)" "unprognostic (8.30e-3)" "unprognostic (1.36e-2)" "unprognostic (1.27e-1)" "unprognostic (8.85e-2)" "unprognostic (1.62e-1)" "unprognostic (8.89e-3)" 15.8 14.5 8.5 18.6 8.9 38.1 16.1 11.4 12.5 12.3 10.4 25.8 19.2 14.8 13.9 23.4 12.4 14.0 17.3 8.3 10.5 16.5 21.9 13.1 29.4 8.4 9.7 12.7 15.1 14.1 12.3 19.7 8.7 11.1 22.4 18.9 14.9 10.2 24.8 13.5 18.3 14.2 7.6 16.8 17.7 21.2 9.6 24.1 11.4 24.0 28.4 21.1 14.3 9.6 28.0 29.4 37.7 30.5 18.2 15.9 48.3 29.1 21.1 35.2 40.1 74.2 33.6 75.1 43.5 18.3 28.9 35.3 46.3 35.9 38.5 46.3 62.0 45.0 35.4 54.4 26.4 36.8 50.5 14.0 41.0 21.8 35.5 19.8 35.2 37.6 47.7 41.3 25.9 36.1 62.7 45.1 40.5 29.7 30.5 54.1 43.5 33.8 32.8 40.8 28.7 24.1 46.6 18.2 55.0 50.5 40.9 50.4 37.6 30.7 37.0 20.2 43.5 35.4 60.6 107.9 24.7 69.6 36.7 49.8 65.6 41.6 44.4 61.7 47.0 102.3 54.1 54.0 66.5 122.4 47.4 48.5 34.7 59.9 66.2 58.3 70.2 48.4 8.5 8.9 11.4 12.5 8.3 10.5 8.4 9.7 8.7 7.6 9.6 9.6 47.4 28.9 37.5 11.8 76.2 33.3 37.5 48.9 26.2 28.2 33.3 22.7 55.7 50.1 42.6 12.9 8.4 46.8 43.6 72.1 33.2 38.6 7.3 39.1 28.8 39.9 37.8 40.4 13.6 67.2 56.7 37.2 27.5 30.9 33.0 29.0 39.7 65.2 47.0 28.6 13.8 57.9 67.1 54.4 61.9 6.3 24.5 37.2 35.6 15.0 48.8 24.3 53.5 16.6 14.4 54.5 77.6 29.7 30.6 31.0 47.4 90.5 42.9 27.9 13.1 34.0 33.0 60.3 72.8 31.5 37.8 61.6 45.2 24.1 52.2 50.6 ZCCHC8 DKFZp434E2220 ENSG00000033030 "Zinc finger CCHC-type containing 8" Q6NZY4 12 122471599-122501073 "Disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 43.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037483, HPA037484" Supported Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA037483: AB_10671502, HPA037484: AB_10672485" "unprognostic (1.96e-3)" "unprognostic (8.48e-2)" "unprognostic (5.55e-2)" "unprognostic (5.24e-2)" "unprognostic (2.44e-1)" "unprognostic (6.30e-3)" "unprognostic (1.33e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (7.40e-4)" "unprognostic (1.03e-1)" "unprognostic (6.95e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (5.36e-4)" "unprognostic (8.86e-2)" "unprognostic (2.88e-1)" "unprognostic (2.55e-2)" "unprognostic (1.48e-2)" 10.2 8.2 3.6 8.9 4.0 43.7 9.9 7.5 4.8 10.8 5.5 9.3 9.0 9.8 8.8 9.8 10.2 6.5 6.3 3.4 3.5 7.9 10.3 8.5 10.5 4.2 3.6 11.5 9.4 8.9 8.9 8.1 3.9 7.9 8.1 10.8 9.7 6.6 16.8 11.8 10.4 7.5 3.0 11.0 10.7 12.1 3.9 10.7 10.8 8.7 11.8 8.9 9.6 5.5 14.8 14.4 21.7 21.0 8.4 10.8 25.2 18.0 11.3 21.5 16.1 13.9 13.0 26.6 10.9 7.6 12.5 17.4 23.1 9.8 19.6 20.9 14.0 17.5 21.0 11.5 19.8 30.5 16.9 9.4 15.7 12.9 18.2 19.2 10.9 26.8 24.3 17.0 11.3 8.4 20.7 23.9 18.5 10.0 15.3 24.2 17.8 21.4 10.5 9.3 15.6 17.2 20.5 9.5 23.0 21.1 20.0 20.3 12.2 14.3 15.3 14.2 17.7 18.2 11.6 36.6 7.8 19.6 8.6 5.5 3.4 2.2 3.5 3.6 3.6 4.5 4.1 4.3 2.8 4.0 4.6 3.8 2.9 4.3 4.3 2.9 5.7 2.5 3.6 4.0 7.5 4.8 3.4 3.5 4.2 3.6 3.9 3.0 3.9 5.5 21.6 32.1 22.6 20.5 26.8 20.5 27.2 13.5 27.3 30.5 23.1 21.5 9.4 21.5 27.0 9.2 125.1 17.4 32.6 13.3 1.9 11.8 78.5 30.7 40.6 21.0 19.6 48.2 21.7 9.5 17.6 22.8 26.0 41.4 19.0 22.5 10.4 17.9 12.8 15.2 24.6 15.5 14.2 15.6 20.2 48.1 14.9 22.4 16.0 26.2 23.5 12.4 21.6 27.6 25.3 14.1 12.2 14.7 29.6 21.3 18.8 6.6 20.4 72.7 6.6 33.6 21.0 34.4 17.1 24.0 25.7 32.3 26.2 19.0 17.3 22.9 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF131 "pHZ-10, ZBTB35" ENSG00000172262 "Zinc finger protein 131" P52739 5 43065176-43192021 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007023, HPA027748, HPA074630" Approved Enhanced "Nucleoplasm,Intermediate filaments" No No "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Intermediate filaments" "HPA007023: AB_2667726, HPA027748: AB_2672374, HPA074630: AB_2686705" "unprognostic (1.23e-1)" "unprognostic (8.24e-2)" "unprognostic (4.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.84e-2)" "unprognostic (7.18e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.52e-1)" "unprognostic (2.98e-3)" "unprognostic (1.94e-2)" "unprognostic (5.83e-2)" "unprognostic (8.07e-2)" "unprognostic (2.09e-2)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (3.11e-3)" "unprognostic (1.46e-2)" 13.2 13.5 12.5 13.9 12.8 28.4 19.5 17.3 21.7 13.8 10.0 13.2 10.0 17.6 9.6 14.4 12.6 12.9 9.6 12.8 12.4 12.0 14.3 11.4 20.3 11.4 11.9 15.9 12.2 11.7 10.7 16.9 11.9 12.6 13.2 14.7 10.4 9.0 15.8 18.2 12.0 15.9 11.3 15.9 11.6 32.6 12.3 26.7 11.8 17.1 17.5 15.0 13.3 14.2 25.4 15.2 32.4 43.2 30.1 20.6 27.3 32.8 26.6 31.9 26.9 24.0 22.2 50.8 25.9 22.1 29.7 17.7 38.9 20.8 44.9 24.8 34.1 31.4 92.2 18.0 27.7 55.0 24.7 18.8 38.2 23.5 38.3 22.8 24.7 39.0 40.7 52.7 36.8 24.5 53.9 68.8 21.5 23.4 24.9 35.3 49.4 39.9 27.1 24.4 20.0 29.4 83.5 39.8 43.2 21.7 22.3 51.6 18.5 39.8 37.3 20.5 31.1 21.1 32.5 58.4 21.0 71.2 27.1 10.4 8.2 5.8 19.1 9.5 19.2 13.1 18.5 18.5 11.9 16.8 22.3 18.3 3.9 17.2 6.6 11.3 14.9 10.0 12.5 12.8 17.3 21.7 12.8 12.4 11.4 11.9 11.9 11.3 12.3 14.2 42.5 22.4 21.9 28.7 44.7 49.6 51.4 24.1 53.5 52.1 32.3 29.7 17.5 22.8 19.4 9.2 52.1 27.0 53.3 28.0 31.3 15.3 52.9 30.0 47.7 32.8 31.2 39.1 31.2 11.8 25.0 32.4 23.0 49.7 24.1 39.4 24.7 13.3 16.4 38.7 33.6 29.7 20.3 25.8 35.4 19.5 20.5 30.9 21.4 14.0 27.5 29.0 49.4 38.7 24.2 17.9 24.7 21.1 27.8 38.5 34.9 13.1 15.7 70.0 26.3 57.0 43.2 109.6 80.3 45.9 65.5 25.4 59.3 37.3 38.7 35.6 ZNF207 BuGZ ENSG00000010244 "Zinc finger protein 207" O43670 17 32350132-32381885 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017013, HPA063908" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA017013: AB_1859124, HPA063908: AB_2685149" "unprognostic (8.40e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.81e-4)" "unprognostic (7.57e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.30e-8)" "unprognostic (2.68e-1)" "unprognostic (4.75e-3)" "unprognostic (8.53e-2)" "unprognostic (5.18e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.17e-8)" "unprognostic (1.28e-2)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" 71.8 65.5 36.8 74.0 40.2 239.5 67.8 50.3 45.3 72.0 44.4 68.7 55.1 70.6 72.0 111.1 62.3 58.5 60.5 38.6 37.7 63.2 63.4 72.3 101.0 39.3 37.2 71.7 55.3 72.0 61.3 78.7 40.7 57.2 81.3 61.9 71.6 56.4 84.5 76.3 63.6 77.8 40.7 69.3 63.6 66.3 39.4 103.8 63.0 62.1 128.6 93.2 78.2 48.0 169.9 203.5 215.8 122.4 113.0 121.3 172.6 165.5 231.9 230.1 205.3 195.2 157.3 231.5 124.8 204.6 178.5 170.6 282.1 200.6 258.1 120.0 188.9 237.9 183.8 202.9 118.2 305.0 209.4 141.3 118.3 162.0 89.6 129.4 215.9 115.5 245.9 173.2 223.9 154.6 245.2 142.5 187.1 160.8 114.8 217.5 193.5 217.0 191.5 324.9 150.6 167.7 155.8 113.2 148.1 183.9 204.8 178.7 154.1 129.4 153.4 132.5 227.8 146.7 235.6 369.5 110.6 141.9 204.9 110.5 75.7 78.1 67.6 84.8 70.2 59.7 61.7 62.7 99.8 44.7 50.8 59.1 38.6 83.9 92.5 47.1 86.9 90.6 36.8 40.2 50.3 45.3 38.6 37.7 39.3 37.2 40.7 40.7 39.4 48.0 119.3 80.1 114.7 135.8 131.1 149.4 195.5 120.8 149.1 134.2 108.8 64.1 32.9 65.8 146.1 64.4 225.2 123.3 191.1 118.2 54.8 94.9 62.0 101.9 116.9 110.1 115.9 125.1 171.2 105.7 175.5 101.3 124.9 144.2 75.3 152.8 85.3 58.4 98.7 101.0 163.0 95.2 93.6 98.8 130.2 26.1 107.2 133.1 55.2 123.7 175.8 55.0 168.9 215.7 257.4 146.5 91.2 97.8 144.9 160.3 101.7 57.7 115.0 141.0 124.9 146.3 145.6 136.3 113.5 175.9 148.5 178.7 143.8 90.0 109.9 250.3 ZNF273 HZF9 ENSG00000198039 "Zinc finger protein 273" Q14593 7 64870172-64930966 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.0;Inhibitory neurons: 51.2;Respiratory ciliated cells: 82.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA077549 Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA077549: AB_2732352" "unprognostic (7.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.80e-2)" "unprognostic (5.87e-4)" "unprognostic (1.83e-1)" "unprognostic (2.31e-1)" "unprognostic (1.97e-2)" "unprognostic (1.65e-2)" "unprognostic (2.02e-5)" "unprognostic (2.54e-1)" "unprognostic (5.76e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (1.04e-2)" "unprognostic (3.14e-1)" "unprognostic (9.48e-2)" "unprognostic (1.85e-2)" 0.4 0.1 0.2 0.2 0.2 2.4 1.2 1.0 0.7 0.8 0.1 0.2 0.3 0.6 0.1 0.5 0.8 0.1 0.2 0.2 0.2 0.2 0.1 0.4 1.1 0.5 0.4 0.9 0.3 0.2 0.0 0.5 0.3 0.4 0.4 0.4 0.4 0.3 0.3 4.0 0.1 0.2 0.3 0.4 0.2 2.1 0.2 1.2 1.5 0.3 1.0 0.4 0.6 0.3 1.8 1.3 2.8 4.1 0.4 0.9 2.3 0.8 0.5 1.2 2.2 2.0 1.6 4.7 2.4 0.4 2.2 0.6 5.6 1.1 1.0 2.3 2.1 2.5 0.6 0.7 0.2 2.4 1.7 0.7 0.7 2.0 1.8 0.8 1.1 6.9 6.7 1.8 1.4 1.6 5.3 2.7 5.7 1.0 2.0 5.5 4.2 2.8 0.6 1.1 2.6 2.7 2.2 1.1 1.3 5.4 2.1 3.5 0.5 1.4 1.5 1.0 1.7 1.7 2.4 6.8 0.3 2.4 1.0 2.0 0.2 1.2 0.3 0.3 0.6 1.2 0.7 0.5 0.6 1.0 0.5 0.9 0.4 0.2 0.2 0.6 0.8 0.3 0.2 0.2 1.0 0.7 0.2 0.2 0.5 0.4 0.3 0.3 0.2 0.3 8.2 3.2 2.3 22.5 12.9 25.0 6.2 8.8 6.8 5.5 7.6 4.7 4.3 1.5 11.1 1.8 0.0 6.8 4.9 0.5 7.9 3.4 25.0 27.1 4.7 7.1 0.0 30.7 44.0 2.9 13.1 7.8 3.6 4.4 3.8 13.4 6.4 1.1 3.6 5.0 51.2 2.0 8.2 3.1 3.5 13.5 6.2 4.1 5.4 15.0 3.9 3.6 7.2 20.1 11.6 2.6 6.1 3.4 2.8 3.6 0.6 1.6 82.0 3.2 0.0 4.8 4.4 21.6 11.4 9.7 18.9 2.9 7.2 5.2 3.5 3.1 ZNF319 "KIAA1388, Zfp319" ENSG00000166188 "Zinc finger protein 319" Q9P2F9 16 57994676-58000672 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 10.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052584 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA052584: AB_2681873" "unprognostic (1.39e-2)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (3.82e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (7.63e-2)" "unprognostic (1.15e-1)" "unprognostic (4.87e-2)" "prognostic favorable (5.87e-5)" "unprognostic (8.69e-2)" "unprognostic (3.72e-3)" "unprognostic (4.49e-1)" "unprognostic (1.82e-1)" "unprognostic (3.53e-2)" "unprognostic (5.80e-2)" 3.8 4.5 4.0 3.6 4.2 11.8 3.6 5.2 4.7 5.1 2.1 5.1 3.1 6.5 2.3 3.0 4.8 1.9 5.2 3.9 4.5 3.6 3.4 3.7 4.1 5.0 4.5 5.8 5.2 6.1 3.8 2.6 4.9 4.0 1.7 2.2 3.8 3.8 5.1 4.2 4.0 3.5 3.7 6.6 3.7 3.8 5.0 3.9 6.4 5.1 2.9 5.8 3.2 4.3 4.5 10.8 6.1 8.7 5.5 6.9 4.8 6.2 6.7 6.6 3.1 5.5 2.9 6.8 10.7 5.2 4.9 4.4 5.4 6.6 4.2 2.9 4.2 3.3 6.4 5.7 10.8 3.9 10.2 8.9 8.1 4.8 11.6 6.2 3.9 5.7 6.2 1.2 5.7 4.3 8.1 5.8 3.7 2.2 10.5 11.5 3.4 7.6 4.1 11.4 4.1 4.4 9.1 4.3 4.3 4.6 1.5 5.8 6.4 5.1 3.1 2.7 4.6 5.6 3.2 6.0 4.0 3.8 5.8 0.0 1.0 3.4 2.1 0.7 1.2 0.5 1.0 1.4 1.1 0.5 0.7 1.1 1.9 0.7 0.6 0.4 0.9 1.4 4.0 4.2 5.2 4.7 3.9 4.5 5.0 4.5 4.9 3.7 5.0 4.3 2.7 3.2 3.4 1.6 1.2 0.9 0.5 2.4 1.2 2.0 1.9 2.4 5.3 5.7 1.6 0.0 0.0 1.6 4.1 1.6 3.9 2.4 0.3 3.2 2.9 2.2 4.9 0.4 0.9 3.0 1.0 2.1 0.0 2.7 1.3 3.3 3.9 2.2 2.3 0.0 1.2 1.5 0.0 7.6 1.0 0.1 3.1 1.8 0.0 1.9 4.3 3.2 10.3 4.0 1.7 2.7 0.5 3.4 1.0 0.8 2.0 1.3 3.7 3.1 0.0 2.4 1.4 2.8 1.1 0.8 1.3 0.3 2.8 3.2 1.2 0.2 ZNF335 "bA465L10.2, NIF-1" ENSG00000198026 "Zinc finger protein 335" Q9H4Z2 20 45948660-45972203 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063999, HPA071230" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA063999: AB_2685170, HPA071230: AB_2686369" "unprognostic (1.50e-1)" "unprognostic (8.05e-2)" "unprognostic (8.29e-3)" "unprognostic (7.85e-2)" "unprognostic (1.35e-2)" "prognostic favorable (4.48e-4)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.74e-2)" "unprognostic (1.01e-1)" "unprognostic (7.91e-2)" "unprognostic (1.30e-3)" "prognostic unfavorable (7.04e-4)" "prognostic unfavorable (2.77e-5)" "unprognostic (4.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.44e-1)" "unprognostic (2.88e-3)" 12.8 12.1 8.2 11.6 8.4 29.6 13.2 11.8 10.0 14.7 5.4 13.2 10.3 13.9 4.2 14.2 14.1 6.5 9.6 8.6 6.4 11.6 12.1 13.1 14.4 6.9 6.4 17.9 15.2 8.3 17.4 6.4 6.9 16.1 5.7 4.8 13.0 7.4 14.6 20.8 17.6 6.7 5.4 22.1 14.4 13.8 6.9 13.3 17.8 7.7 10.2 12.5 12.7 8.7 12.6 12.6 11.0 11.9 5.7 7.2 23.2 11.0 7.6 10.7 7.7 27.3 13.8 15.0 16.0 10.9 9.8 17.7 10.7 16.6 4.9 10.3 14.6 12.6 20.0 14.6 8.8 16.4 20.5 11.6 13.8 14.1 10.0 7.7 9.3 15.5 12.0 19.6 7.5 25.7 19.4 15.8 7.5 8.4 20.4 15.8 7.3 12.7 9.5 19.5 11.0 9.7 16.4 22.7 11.6 6.5 17.2 13.4 9.8 23.0 10.0 14.8 15.2 22.7 12.6 15.4 18.6 10.0 12.9 1.2 1.7 2.4 3.3 2.2 1.6 1.4 1.6 2.2 1.7 1.5 1.3 1.5 1.7 4.2 1.8 1.2 1.8 2.0 8.2 8.4 11.8 10.0 8.6 6.4 6.9 6.4 6.9 5.4 6.9 8.7 16.9 12.8 15.0 16.6 17.3 18.7 12.1 5.3 14.8 19.3 13.7 14.2 3.8 5.7 5.9 1.8 27.1 8.1 21.5 22.7 0.0 4.4 32.1 10.0 12.3 10.9 21.5 5.7 14.8 5.9 8.5 9.5 22.4 15.4 7.0 15.2 7.1 5.1 6.1 13.5 12.4 11.7 6.1 10.0 11.3 24.8 7.5 14.5 8.8 9.4 6.7 6.0 21.6 7.1 12.4 7.9 12.7 5.3 18.5 10.5 14.6 2.7 4.6 11.6 0.0 21.7 10.3 3.8 7.2 12.9 22.4 11.9 23.1 7.8 12.3 12.8 ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA015319: AB_2669185, HPA015785: AB_2217750" "unprognostic (5.91e-2)" "unprognostic (2.78e-3)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.57e-3)" "unprognostic (7.76e-3)" "unprognostic (1.60e-3)" "unprognostic (4.35e-2)" "unprognostic (3.01e-1)" "unprognostic (3.78e-3)" "unprognostic (2.71e-2)" "unprognostic (4.88e-3)" "unprognostic (3.23e-3)" "unprognostic (1.72e-1)" "prognostic favorable (2.34e-4)" "unprognostic (2.28e-1)" 1.4 0.6 0.7 3.7 1.3 26.1 1.7 1.4 1.3 1.1 0.2 3.0 2.9 1.1 0.1 2.4 0.7 1.0 2.1 0.7 1.0 3.0 10.8 1.1 4.6 1.5 1.4 1.0 1.4 1.6 0.3 1.9 1.4 1.2 3.3 1.3 0.7 0.4 1.5 3.5 3.0 2.4 0.9 1.3 2.1 6.1 1.3 8.7 1.1 2.7 4.7 1.5 1.2 2.7 25.4 10.3 9.9 8.9 3.8 5.3 13.4 34.6 20.4 16.9 20.0 6.4 17.5 19.2 14.4 16.5 12.6 30.5 11.6 12.6 19.9 21.2 10.0 14.0 19.1 5.3 0.0 19.8 16.5 0.9 0.8 13.7 6.9 3.7 6.3 13.3 13.0 45.4 21.7 16.9 30.4 16.1 6.7 27.9 16.7 15.3 49.9 11.7 4.9 16.8 17.4 12.0 15.3 18.1 10.6 8.0 9.4 17.3 5.7 27.6 15.8 25.6 26.6 17.6 32.0 7.8 16.7 17.0 23.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.7 1.3 1.4 1.3 0.7 1.0 1.5 1.4 1.4 0.9 1.3 2.7 1.1 0.0 0.0 2.9 3.8 9.9 1.3 0.4 10.8 0.7 2.2 2.3 2.6 0.0 0.9 0.0 0.0 3.2 2.5 2.4 0.0 0.5 0.7 0.6 1.1 2.0 0.0 22.3 5.1 1.2 4.2 1.7 2.6 1.8 0.0 4.7 1.1 3.8 1.9 0.0 5.3 3.6 0.0 2.1 2.6 0.8 0.6 8.3 3.6 2.8 0.1 0.6 1.0 3.0 7.9 0.7 0.5 0.7 9.6 0.6 0.9 2.5 0.0 1.5 6.6 2.0 3.6 10.3 1.7 10.9 6.5 0.8 5.0 0.3 5.6 1.1 ZNF410 "APA-1, APA1" ENSG00000119725 "Zinc finger protein 410" Q86VK4 14 73886617-73932521 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.7;Excitatory neurons: 22.7;Inhibitory neurons: 23.8;Oligodendrocytes: 31.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002871 Approved "Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nuclear bodies" "HPA002871: AB_1080712" "unprognostic (5.84e-2)" "unprognostic (5.04e-2)" "unprognostic (9.29e-2)" "unprognostic (6.36e-3)" "unprognostic (5.86e-4)" "unprognostic (4.91e-2)" "unprognostic (2.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.79e-2)" "unprognostic (2.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.19e-1)" 29.0 33.0 26.8 18.7 30.4 57.7 29.4 30.9 33.9 30.0 28.9 30.6 19.0 27.5 43.7 33.4 28.1 22.6 21.0 26.3 28.0 33.0 28.8 27.6 25.6 29.1 27.5 38.7 20.6 27.1 27.0 32.2 29.6 29.5 24.4 22.8 24.4 27.3 21.1 37.6 25.2 28.4 26.7 26.1 25.7 44.7 28.3 29.9 24.6 18.3 30.7 29.1 28.7 37.0 46.7 35.8 42.4 45.2 44.8 39.8 52.4 51.4 56.9 88.2 82.0 37.6 40.1 38.4 21.7 65.7 28.2 42.1 42.9 52.8 83.2 56.2 26.9 36.2 31.6 29.9 67.4 30.6 45.6 37.0 72.4 44.5 83.1 39.5 47.5 43.9 38.2 33.0 43.3 88.6 45.8 51.2 15.5 56.3 41.7 40.7 48.5 24.7 57.0 43.7 39.0 50.3 57.2 52.5 54.6 35.5 48.3 52.2 30.7 62.7 59.0 37.1 47.2 45.2 83.4 48.0 40.1 34.1 53.7 65.9 45.3 74.8 47.5 43.1 51.9 37.7 49.0 49.0 45.6 43.0 42.3 43.5 34.4 60.5 50.1 30.8 46.7 55.9 26.8 30.4 30.9 33.9 26.3 28.0 29.1 27.5 29.6 26.7 28.3 37.0 4.3 0.0 3.1 27.7 10.8 0.6 1.5 1.0 10.8 1.5 2.2 1.7 1.1 0.0 2.9 0.0 4.2 1.8 5.0 1.7 0.0 1.0 3.8 4.7 5.6 2.6 0.0 5.9 22.7 0.9 1.5 5.3 10.7 6.7 10.8 2.9 1.8 0.4 1.2 1.7 23.8 1.1 0.0 2.2 3.1 1.1 1.2 5.4 1.8 18.7 1.1 2.4 2.1 18.1 31.0 1.3 1.4 0.4 13.4 1.0 2.4 0.7 0.2 4.7 0.0 4.0 5.1 3.3 1.9 10.1 1.1 2.6 10.5 4.1 0.8 1.4 ZNF431 KIAA1969 ENSG00000196705 "Zinc finger protein 431" Q8TF32 19 21142024-21196053 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Granulosa cells: 132.7;Theca cells: 185.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA059135 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA059135: AB_2683918" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-2)" "unprognostic (1.37e-2)" "unprognostic (9.08e-2)" "unprognostic (2.30e-2)" "unprognostic (7.86e-2)" "unprognostic (1.97e-3)" "unprognostic (2.93e-3)" "unprognostic (5.91e-2)" "unprognostic (9.37e-3)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.29e-2)" "unprognostic (3.01e-3)" 5.0 10.3 2.5 6.1 3.4 14.6 7.3 7.5 3.4 8.3 0.4 4.0 3.4 5.7 6.9 19.2 4.9 3.1 7.6 2.1 2.8 3.7 1.2 6.7 9.4 2.9 3.8 21.9 7.1 4.9 3.5 5.6 4.3 5.1 5.0 7.1 6.7 3.3 5.2 11.6 4.8 4.6 1.5 6.7 6.4 8.3 2.8 9.6 12.3 5.7 8.3 4.5 11.3 5.9 11.0 3.1 9.7 11.4 2.7 5.4 14.7 5.6 4.9 10.5 10.4 6.0 7.7 13.9 9.6 3.8 4.9 7.2 8.5 6.1 12.8 5.0 10.7 10.6 8.3 3.7 2.6 5.3 10.7 3.9 10.9 6.6 6.3 5.9 8.2 12.3 19.5 8.1 6.3 4.7 16.9 5.9 11.3 4.2 9.2 9.2 12.4 3.9 4.1 12.6 9.3 7.8 14.5 0.1 5.1 15.3 6.0 9.3 5.0 6.6 0.5 9.1 8.2 6.4 12.9 18.1 1.6 9.2 4.5 4.1 3.4 7.1 2.8 3.1 4.1 8.1 4.9 3.8 2.4 8.0 6.0 4.7 5.0 8.6 4.3 5.8 4.1 1.8 2.5 3.4 7.5 3.4 2.1 2.8 2.9 3.8 4.3 1.5 2.8 5.9 17.5 121.8 22.1 7.2 32.0 12.6 15.0 8.0 15.4 32.8 13.6 13.7 17.3 12.8 20.1 23.9 37.5 17.6 34.4 9.0 3.9 12.6 3.7 23.2 30.5 16.5 16.9 19.3 12.5 8.8 18.4 19.9 24.5 52.5 20.3 132.7 17.5 0.6 10.7 15.2 12.5 10.2 12.2 17.9 11.3 5.4 32.6 16.4 3.6 19.7 16.0 11.3 43.3 16.6 24.0 14.0 3.1 21.4 21.2 17.8 5.5 4.5 11.9 30.8 19.7 25.2 23.2 26.7 16.1 26.0 15.5 11.6 27.1 185.6 10.4 31.7 ZNF492 "KIAA1473, ZNF115" ENSG00000229676 "Zinc finger protein 492" Q9P255 19 22634324-22667671 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;testis: 1.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 6.9;Granulosa cells: 5.4;Spermatocytes: 8.1;Spermatogonia: 9.1" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.6;HAP1: 3.3;NB-4: 4.3;NTERA-2: 4.1;U-2197: 3.9" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.14e-1)" "unprognostic (1.24e-3)" "unprognostic (7.94e-2)" "unprognostic (2.42e-2)" "unprognostic (1.47e-2)" "unprognostic (6.75e-2)" "unprognostic (1.08e-3)" "unprognostic (5.63e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.91e-2)" "unprognostic (2.65e-1)" "unprognostic (8.93e-2)" "unprognostic (6.04e-2)" 0.3 0.0 0.2 0.1 0.1 2.6 0.7 0.8 0.5 0.3 0.2 0.2 0.0 0.2 0.1 0.2 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.3 0.1 0.1 0.5 0.2 0.3 0.0 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.1 1.9 0.1 0.7 0.3 0.1 0.3 0.1 0.1 0.3 0.0 0.0 1.4 0.1 0.0 0.0 5.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 2.0 0.7 2.4 0.0 3.3 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.1 0.0 0.0 0.0 2.2 0.9 0.1 0.0 0.5 0.0 4.3 4.1 0.0 0.1 0.0 0.0 0.6 0.5 1.0 0.0 2.3 0.0 0.0 0.3 0.9 1.7 1.5 0.0 0.0 2.1 3.9 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.8 0.5 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.9 0.0 3.8 1.3 1.0 0.5 1.2 0.0 1.8 1.8 1.0 1.1 1.0 0.0 0.6 0.0 0.0 1.0 0.4 0.2 0.0 0.5 0.7 0.5 1.2 1.3 0.0 6.9 0.3 0.2 2.4 1.1 0.0 0.6 1.3 5.4 1.1 0.1 0.1 3.3 0.2 0.2 0.0 0.3 1.1 0.4 0.9 0.5 0.0 1.9 0.1 1.0 0.0 3.0 0.6 0.2 0.2 0.4 0.0 0.9 0.0 0.0 1.5 2.4 0.0 0.6 1.2 8.1 9.1 0.6 0.6 0.5 0.5 0.8 0.3 0.7 ZNF687 KIAA1441 ENSG00000143373 "Zinc finger protein 687" Q8N1G0 1 151281618-151292176 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Group enriched" "Detected in many" 8 "granulocytes: 13.5;monocytes: 4.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021193, HPA023948" Approved Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA021193: AB_1859415, HPA023948: AB_2671380" "unprognostic (2.23e-1)" "unprognostic (3.25e-1)" "unprognostic (2.93e-2)" "unprognostic (9.64e-3)" "unprognostic (2.44e-2)" "unprognostic (7.82e-2)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (9.91e-2)" "unprognostic (8.69e-3)" "unprognostic (2.10e-1)" "unprognostic (5.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.41e-1)" "unprognostic (8.54e-2)" "unprognostic (7.99e-2)" 8.5 10.9 9.0 8.2 9.9 31.2 8.7 12.6 10.2 9.9 6.9 10.7 8.6 10.5 5.5 11.0 9.7 7.0 8.9 8.5 8.4 10.2 9.7 8.6 10.1 10.5 9.6 11.7 16.0 14.1 13.0 7.1 9.5 11.3 5.7 9.4 12.0 8.6 10.9 12.3 11.3 6.1 8.9 14.4 10.8 14.5 9.7 9.3 10.8 6.9 7.5 10.4 8.7 10.5 14.8 21.5 20.4 12.6 11.3 9.5 26.3 7.6 12.9 13.8 13.1 18.1 19.6 12.6 18.7 12.3 14.7 22.3 18.1 15.2 6.1 17.3 18.3 11.9 18.8 20.1 12.1 14.3 16.7 14.7 15.3 11.6 12.1 12.3 9.4 13.4 19.5 22.6 7.8 44.8 19.2 16.8 27.6 19.8 16.5 16.9 16.1 22.8 11.6 22.1 18.5 27.7 20.8 24.6 19.7 19.2 32.2 30.1 9.2 11.0 12.1 13.9 11.6 26.2 24.1 31.3 14.0 9.4 14.2 0.5 1.8 13.5 0.5 2.3 0.5 1.0 0.5 0.4 0.9 1.1 0.7 0.8 8.8 0.4 4.5 0.8 0.4 1.2 9.0 9.9 12.6 10.2 8.5 8.4 10.5 9.6 9.5 8.9 9.7 10.5 4.3 3.2 4.6 3.6 5.8 4.7 2.8 4.9 5.7 6.7 6.0 5.5 1.4 10.0 3.5 1.8 10.4 6.7 3.8 9.3 3.9 5.5 3.1 4.3 3.7 4.4 2.4 3.0 1.6 6.0 5.3 4.2 7.7 5.3 0.0 8.5 2.9 4.5 5.3 8.4 1.9 5.6 8.2 5.2 4.1 2.8 6.2 5.8 0.0 2.8 6.0 5.2 5.2 3.0 1.7 7.3 3.5 7.2 5.8 4.7 10.2 4.1 3.4 10.8 13.1 4.4 3.9 6.9 6.8 4.3 3.4 9.4 4.3 6.5 7.3 5.1 ZNF800 ENSG00000048405 "Zinc finger protein 800" Q2TB10 7 127346790-127431924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 74.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023090, HPA052194" Approved Supported "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoli, Nucleoli rim" Cytosol "HPA023090: AB_1859457, HPA052194: AB_2681757" "unprognostic (2.93e-2)" "unprognostic (1.10e-1)" "unprognostic (2.27e-1)" "unprognostic (3.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-2)" "unprognostic (6.19e-2)" "unprognostic (2.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (8.99e-2)" "unprognostic (7.04e-2)" "unprognostic (1.32e-1)" "unprognostic (1.08e-1)" "unprognostic (2.53e-2)" "unprognostic (8.96e-3)" 10.7 7.2 5.7 11.6 7.3 74.6 12.0 20.2 5.0 8.4 1.4 10.8 10.4 9.6 7.9 12.5 7.8 11.3 6.0 2.9 4.4 8.2 14.7 10.2 16.6 5.4 6.3 10.3 12.5 11.3 3.5 9.2 5.9 9.3 10.1 9.9 8.2 7.7 5.7 10.6 10.7 9.5 5.9 13.2 11.4 20.6 6.3 13.2 11.0 7.2 14.3 10.5 5.5 7.9 16.0 8.4 9.5 16.5 13.5 17.3 9.2 14.9 17.5 15.1 14.6 7.8 15.0 27.1 9.0 14.6 16.3 11.1 15.7 15.6 20.9 23.9 9.5 17.7 8.5 7.1 16.9 24.2 32.3 15.4 14.9 16.2 22.0 12.5 16.5 16.3 22.3 27.0 16.9 12.4 26.5 17.2 7.9 14.5 10.8 16.7 13.3 18.0 11.0 19.8 13.6 13.9 14.8 58.7 19.8 12.9 7.0 16.3 18.0 25.0 8.0 17.2 18.1 31.7 15.2 39.0 18.8 21.5 21.8 22.1 8.7 13.6 16.1 8.0 16.3 15.4 11.8 16.5 9.0 17.3 19.2 21.0 7.5 25.0 9.0 15.3 18.6 8.0 5.7 7.3 20.2 5.0 2.9 4.4 5.4 6.3 5.9 5.9 6.3 7.9 49.0 38.5 23.5 27.7 65.1 44.7 51.7 14.7 52.3 29.0 28.3 20.6 16.8 11.5 20.1 12.9 22.9 12.0 70.5 30.2 11.7 24.1 44.8 22.2 30.8 37.2 16.2 52.0 46.4 19.2 14.0 32.0 40.2 26.3 29.2 26.3 26.7 17.5 14.4 77.4 35.5 29.3 8.2 25.3 34.1 11.3 27.1 41.7 28.4 45.9 37.9 17.5 79.3 41.7 71.8 24.5 22.0 31.6 57.8 48.3 26.8 13.3 18.3 27.9 26.3 54.9 30.1 111.9 39.9 44.4 47.9 22.0 65.5 30.1 25.5 68.5 ZNF850 ZNF850P ENSG00000267041 "Zinc finger protein 850" A8MQ14 19 36714383-36772825 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.1" "Cell type enhanced" "Detected in many" "Early spermatids: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 15.2;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029299 Uncertain Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA029299: AB_2672987" "unprognostic (1.35e-2)" "unprognostic (5.54e-2)" "unprognostic (3.85e-2)" "unprognostic (1.38e-3)" "unprognostic (7.78e-2)" "unprognostic (6.63e-2)" "unprognostic (1.65e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-2)" "unprognostic (1.25e-1)" "unprognostic (3.00e-2)" "unprognostic (5.56e-2)" "unprognostic (4.11e-3)" "unprognostic (1.77e-1)" "unprognostic (7.49e-2)" "unprognostic (4.49e-2)" "unprognostic (7.37e-3)" 0.8 0.6 0.7 1.0 0.6 5.1 0.9 2.4 1.0 0.7 0.9 0.7 0.6 0.7 0.3 1.0 0.7 0.8 1.6 1.5 0.7 0.6 0.9 0.7 1.5 0.9 0.7 1.2 0.6 1.0 0.5 3.1 0.8 0.9 1.0 1.0 0.7 0.7 0.4 1.2 0.6 0.8 0.3 1.1 0.7 2.6 0.7 0.7 0.7 0.5 0.8 0.5 0.5 1.4 0.3 1.7 3.7 6.0 0.8 0.2 7.0 2.2 1.3 1.5 1.8 1.3 0.4 1.2 5.1 0.4 7.6 1.1 2.6 0.5 2.7 0.8 2.3 15.2 0.3 1.2 1.0 1.8 8.6 1.0 0.1 2.3 0.0 0.5 1.3 1.8 4.4 0.8 3.6 0.8 2.7 1.7 11.9 0.6 1.0 1.7 7.8 1.1 0.7 7.5 2.4 3.8 3.5 0.2 0.5 5.0 1.5 3.3 2.9 3.6 5.9 2.1 3.7 1.4 2.7 3.2 0.0 0.9 5.6 1.8 1.2 0.9 1.3 1.3 1.7 2.7 1.6 1.1 1.1 1.7 1.8 2.0 1.9 1.3 1.5 1.2 1.2 2.2 0.7 0.6 2.4 1.0 1.5 0.7 0.9 0.7 0.8 0.3 0.7 1.4 2.4 0.0 0.0 0.7 1.7 2.2 1.3 0.5 1.8 1.1 1.9 1.5 5.1 1.5 0.2 3.7 0.0 4.4 1.3 0.3 0.0 1.0 8.0 1.6 1.5 2.9 0.0 5.7 1.3 0.7 5.4 3.0 0.5 2.4 0.0 3.6 7.1 2.1 1.3 5.0 1.0 3.5 2.0 2.2 2.1 3.3 1.2 0.8 3.6 1.9 0.5 1.2 2.1 3.0 3.7 0.6 0.4 0.4 0.7 0.8 0.1 0.7 0.2 0.5 0.0 2.5 1.6 5.9 5.7 1.1 3.4 2.9 1.1 1.7 0.8 0.9 ZUP1 "C6orf113, dJ412I7.3, ZUFSP" ENSG00000153975 "Zinc finger containing ubiquitin peptidase 1" Q96AP4 6 116635618-116668794 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.4;dendritic cells: 12.8;monocytes: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044426 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA044426: AB_10960887" "unprognostic (2.28e-3)" "unprognostic (2.45e-3)" "unprognostic (3.91e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.27e-1)" "unprognostic (5.88e-2)" "unprognostic (2.83e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (1.90e-3)" "unprognostic (2.54e-2)" "unprognostic (1.48e-1)" "unprognostic (7.33e-2)" "unprognostic (7.92e-3)" 4.4 4.5 4.2 6.2 4.7 13.5 5.6 7.2 6.3 4.0 3.0 5.1 10.5 3.6 4.1 5.6 3.1 5.5 2.7 4.3 4.6 4.6 4.3 5.0 8.7 4.4 4.4 2.5 5.7 4.2 3.9 5.3 4.6 5.0 5.7 6.0 3.8 4.0 3.1 5.5 7.1 4.1 4.5 6.0 4.7 6.1 4.7 7.5 4.6 3.3 8.7 6.1 4.1 5.9 6.6 6.3 13.9 26.2 7.9 10.3 10.4 14.0 13.3 13.5 16.3 11.5 7.3 23.3 11.6 8.9 15.2 10.3 15.8 10.1 17.9 14.0 18.1 18.0 9.5 20.0 12.3 21.1 21.3 9.2 15.7 11.0 18.7 10.0 12.5 17.4 32.1 11.6 17.9 10.7 10.2 16.0 10.3 9.9 6.8 13.9 12.1 9.6 15.0 6.6 12.1 14.0 10.0 8.3 8.6 11.8 4.9 15.9 10.7 8.6 5.8 5.3 11.9 10.7 14.9 24.0 7.7 12.8 12.8 19.5 7.5 7.6 7.0 8.9 8.2 9.5 7.9 8.1 10.1 10.4 8.6 6.4 2.9 8.3 11.0 6.9 11.7 6.5 4.2 4.7 7.2 6.3 4.3 4.6 4.4 4.4 4.6 4.5 4.7 5.9 6.7 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 5.3 5.2 0.0 0.0 0.0 1.8 0.0 10.4 12.8 0.0 9.8 9.7 0.0 7.4 8.7 2.2 0.0 0.0 0.0 8.0 8.3 2.2 0.0 8.4 0.0 10.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 12.4 0.0 0.0 0.0 0.0 10.0 0.0 0.0 3.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 9.3 4.4 6.0 0.0 0.0 ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Mitochondria "HPA031778: AB_10599831, HPA031790: AB_10600999" "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (6.75e-2)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.80e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "prognostic favorable (6.08e-4)" "unprognostic (1.54e-1)" "unprognostic (1.38e-3)" "unprognostic (6.09e-3)" "unprognostic (1.80e-1)" "unprognostic (9.43e-2)" "unprognostic (6.46e-2)" 10.2 10.6 6.4 10.1 6.7 20.8 9.7 7.4 7.3 8.4 18.3 19.2 15.5 9.9 5.7 11.1 9.1 6.4 11.0 7.1 6.0 7.6 9.0 11.3 10.1 8.0 6.9 10.1 14.2 12.1 11.2 6.0 7.8 10.1 14.6 11.2 9.1 7.4 22.2 12.1 27.5 8.8 5.8 14.2 12.0 8.0 8.5 15.1 10.7 13.3 9.7 10.9 8.1 7.5 13.1 20.1 7.1 9.7 17.4 9.8 8.5 11.1 13.9 12.7 12.3 10.0 4.5 12.4 7.3 15.0 8.4 14.6 14.4 7.6 12.9 14.5 15.0 12.0 16.4 6.5 11.8 10.2 22.6 12.6 10.0 12.5 14.7 6.6 16.6 12.3 8.8 12.2 8.0 8.9 12.7 6.0 4.3 12.5 7.6 14.0 8.6 5.4 7.1 13.2 5.6 8.2 12.6 7.7 10.8 7.0 7.6 7.7 19.7 11.1 5.6 14.1 14.7 5.4 3.0 6.3 11.1 8.9 10.5 0.7 0.6 0.6 0.8 0.9 1.0 0.4 0.5 0.5 0.5 0.3 0.3 0.6 1.0 0.2 1.0 0.4 0.4 0.4 6.4 6.7 7.4 7.3 7.1 6.0 8.0 6.9 7.8 5.8 8.5 7.5 19.3 57.7 54.8 39.8 23.5 7.1 5.4 6.6 13.1 30.6 12.6 10.3 22.8 18.6 30.0 9.2 98.0 8.3 23.7 93.4 0.0 7.3 48.9 18.8 17.4 19.2 13.2 12.4 50.3 11.2 6.4 21.6 46.4 25.6 26.5 21.8 23.2 15.2 11.9 40.4 55.3 38.5 12.2 30.5 10.6 26.8 14.9 29.0 12.4 22.5 20.4 15.8 19.6 35.2 53.6 14.9 34.3 9.8 27.8 9.5 115.2 4.8 22.7 50.3 6.6 23.7 15.2 12.0 11.8 16.4 10.1 8.9 31.1 18.0 28.6 9.3