Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Cytosol" "HPA039371: AB_10805476, HPA040174: AB_10805605" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.25e-2)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.84e-2)" "unprognostic (4.52e-2)" "unprognostic (9.10e-2)" "unprognostic (5.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.88e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (1.53e-1)" 15.1 19.1 10.5 19.2 13.3 19.8 22.5 7.2 14.5 17.9 12.7 27.8 15.8 14.8 25.9 20.5 16.5 18.5 15.8 12.9 15.7 27.4 18.1 15.6 19.9 9.8 11.5 8.0 17.0 35.2 19.0 15.8 11.5 18.8 33.8 22.1 15.4 20.5 32.8 12.9 19.5 21.2 9.5 15.4 23.9 21.9 15.7 29.9 33.0 23.0 25.9 27.5 13.2 12.2 49.7 89.9 63.2 64.8 60.0 49.3 31.1 51.4 74.7 60.6 68.7 66.8 52.9 48.1 51.1 52.9 74.4 98.2 129.9 59.4 62.9 65.0 62.0 46.2 63.2 26.8 66.0 78.8 51.2 48.6 80.6 45.8 94.3 41.0 47.8 59.7 96.5 63.7 60.2 61.3 47.6 32.7 53.1 61.7 31.5 53.1 81.1 57.7 55.9 116.1 89.7 57.3 60.7 44.0 75.7 54.7 71.5 59.2 51.7 54.2 64.5 50.0 73.0 33.7 119.3 69.2 52.7 71.8 55.4 56.4 27.0 28.2 31.3 35.4 36.2 22.0 28.2 29.7 33.2 17.3 23.7 25.0 14.6 42.7 38.1 25.4 37.3 30.2 10.5 13.3 7.2 14.5 12.9 15.7 9.8 11.5 11.5 9.5 15.7 12.2 10.8 3.2 7.7 26.1 19.0 12.0 18.8 19.4 15.9 13.4 17.8 10.3 12.9 4.3 19.0 27.6 27.1 16.3 8.8 33.4 17.6 28.6 14.6 14.5 11.6 12.0 15.7 10.9 45.4 31.2 14.8 14.1 22.4 18.0 10.8 8.2 8.2 12.7 17.0 18.5 33.1 17.3 14.2 15.5 8.4 8.6 7.8 11.6 7.2 30.0 21.3 14.4 16.5 26.2 31.9 25.3 20.9 11.3 15.5 22.9 15.3 19.1 20.5 19.4 13.1 10.5 10.2 43.0 33.8 17.6 13.8 16.6 17.8 25.3 15.7 24.5 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABCF3 EST201864 ENSG00000161204 "ATP binding cassette subfamily F member 3" Q9NUQ8 3 184186023-184194012 "Predicted intracellular proteins, Transporters" "Antiviral defense" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036332 Approved Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoli "HPA036332: AB_10603571" "unprognostic (1.70e-2)" "unprognostic (1.16e-1)" "unprognostic (3.10e-2)" "unprognostic (3.81e-2)" "unprognostic (4.11e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.16e-5)" "unprognostic (5.18e-2)" "unprognostic (5.97e-2)" "unprognostic (2.67e-1)" "unprognostic (1.01e-1)" "unprognostic (5.52e-2)" "unprognostic (1.85e-2)" "unprognostic (3.72e-2)" "unprognostic (1.44e-1)" "unprognostic (1.94e-2)" "unprognostic (6.53e-2)" 16.1 56.1 10.9 13.3 10.9 16.8 15.8 11.8 13.4 18.2 9.6 15.5 15.7 15.5 12.3 20.0 17.0 12.7 28.5 10.9 12.7 19.2 22.7 14.4 17.0 13.9 12.3 20.0 23.6 43.5 21.0 16.4 12.8 16.2 13.6 14.2 26.9 19.6 46.8 19.6 16.3 12.4 9.2 17.8 17.5 16.5 12.4 14.6 17.9 41.3 16.1 17.1 17.6 11.6 49.9 30.2 16.9 32.8 48.1 26.9 33.3 35.2 39.1 46.7 36.5 52.0 19.3 29.8 69.5 38.1 54.9 46.4 26.5 37.1 24.1 38.4 25.5 25.7 26.6 30.8 40.4 29.2 25.2 39.7 33.5 33.1 32.7 27.4 33.8 25.7 24.1 34.9 33.5 60.0 28.7 18.8 25.7 51.1 41.2 28.5 28.1 50.4 25.4 29.6 29.1 16.9 36.5 69.1 33.8 18.3 93.7 25.3 33.5 24.9 27.1 39.5 53.1 39.2 40.5 38.2 38.8 28.7 31.3 8.1 29.1 22.7 32.9 30.4 34.7 23.6 29.0 27.5 25.6 23.8 36.0 29.5 14.6 24.0 32.4 15.8 27.2 37.2 10.9 10.9 11.8 13.4 10.9 12.7 13.9 12.3 12.8 9.2 12.4 11.6 10.2 9.6 2.0 6.2 17.4 14.5 10.0 29.8 9.6 16.7 10.8 6.7 11.6 17.2 19.7 14.7 14.6 36.9 16.2 19.8 29.4 22.5 9.5 11.2 12.0 11.6 11.4 8.6 7.1 22.4 25.5 12.5 13.3 12.0 9.5 16.0 16.8 20.0 21.6 20.2 9.9 13.4 30.5 9.4 6.9 10.2 12.5 12.9 16.0 3.7 22.8 14.7 17.5 6.6 7.3 20.5 9.8 11.7 19.4 9.0 28.6 37.3 14.4 22.3 6.6 11.9 9.5 12.8 17.1 14.5 10.2 43.8 16.6 18.1 14.7 11.7 ABHD18 "C4orf29, FLJ21106" ENSG00000164074 "Abhydrolase domain containing 18" Q0P651 4 127965306-128039953 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050168, HPA051676" Approved Approved "Nuclear membrane" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear membrane" "HPA050168: AB_2681040, HPA051676: AB_2681571" "unprognostic (1.91e-1)" "unprognostic (8.66e-2)" "prognostic favorable (5.35e-4)" "unprognostic (1.74e-2)" "unprognostic (4.99e-2)" "unprognostic (2.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.51e-2)" "unprognostic (5.60e-2)" "unprognostic (3.34e-1)" "unprognostic (1.14e-2)" "unprognostic (1.76e-3)" "unprognostic (2.17e-3)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" "unprognostic (7.32e-2)" "prognostic favorable (9.13e-4)" 4.3 4.2 2.4 5.3 3.0 5.8 4.0 6.5 3.3 4.3 2.0 5.3 7.1 4.0 4.2 4.0 4.5 2.4 13.5 2.5 3.7 4.6 8.4 3.9 5.8 2.4 2.2 5.1 8.9 3.3 5.2 2.9 2.6 3.6 5.1 5.4 4.8 2.2 10.9 5.5 7.0 3.2 1.8 4.8 4.6 1.9 2.9 5.9 4.8 11.7 4.9 4.1 4.1 3.2 4.2 3.5 4.1 5.3 3.2 4.4 6.1 4.0 3.2 3.5 4.6 7.8 7.7 11.1 6.5 2.0 3.3 4.0 8.7 4.7 3.8 9.2 2.8 8.2 5.1 6.7 4.4 13.9 10.1 3.4 3.2 3.7 2.4 4.1 6.3 8.4 13.8 8.0 3.3 7.4 18.7 6.8 4.3 8.7 3.1 10.2 1.4 7.2 5.2 4.2 9.4 3.4 4.1 6.8 4.1 5.8 6.0 5.7 5.4 2.3 3.1 5.7 4.0 14.8 15.4 13.2 4.0 14.7 3.7 13.6 5.7 8.7 5.0 5.0 3.9 6.3 6.3 6.0 4.7 7.8 7.2 7.1 12.1 4.5 3.7 7.8 7.2 2.9 2.4 3.0 6.5 3.3 2.5 3.7 2.4 2.2 2.6 1.8 2.9 3.2 8.4 6.4 15.4 0.0 17.6 0.0 8.7 0.0 17.1 13.5 5.9 3.7 0.0 8.6 5.6 7.3 20.9 5.5 13.5 7.9 0.0 5.1 3.5 6.3 5.7 6.9 6.1 27.3 0.0 7.3 4.7 4.8 23.4 8.2 1.3 10.6 11.4 23.4 7.8 18.5 0.0 9.6 0.0 17.6 0.0 1.6 6.2 12.9 0.0 0.0 15.9 5.1 12.3 0.0 0.0 7.5 5.6 5.7 21.3 10.2 13.9 8.5 3.6 19.8 13.1 8.0 4.2 9.2 4.8 12.0 0.0 9.2 14.5 7.8 8.4 9.4 ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Collecting duct cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA037591: AB_10671877, HPA037592: AB_2675566, HPA074089: AB_2686659" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (6.81e-2)" "unprognostic (3.72e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.09e-2)" "unprognostic (1.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" 9.1 10.5 8.0 10.3 8.3 12.3 12.2 8.0 9.9 8.8 6.6 9.9 10.2 9.4 9.3 9.8 9.0 8.2 10.0 8.4 8.6 12.3 13.7 9.3 12.5 7.8 8.4 10.4 8.3 12.7 3.9 10.3 8.5 9.5 10.3 5.3 8.5 8.8 19.0 11.6 10.8 10.5 7.7 10.0 9.5 6.7 8.2 12.9 12.7 16.2 13.3 9.7 6.8 7.9 22.2 14.9 15.7 21.6 19.9 19.6 13.5 22.4 35.1 26.2 24.1 12.1 20.9 24.7 18.6 24.4 14.2 24.4 25.0 21.0 27.5 21.6 17.2 18.8 11.8 15.0 25.4 32.6 18.9 21.6 25.1 25.8 46.4 28.3 20.1 21.7 20.0 16.6 21.6 14.5 25.1 29.1 13.5 20.0 13.8 20.0 16.6 15.1 19.5 11.1 10.8 19.8 17.9 17.0 24.4 15.8 14.0 22.2 17.4 14.0 11.2 16.5 27.1 17.2 17.1 23.6 18.3 15.9 10.1 22.8 10.5 9.8 7.6 14.5 10.5 10.5 8.8 10.6 12.9 11.6 9.3 10.3 4.1 7.7 11.8 8.7 11.4 7.0 8.0 8.3 8.0 9.9 8.4 8.6 7.8 8.4 8.5 7.7 8.2 7.9 15.1 25.6 14.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.4 10.3 0.0 0.0 6.2 23.9 0.0 16.9 7.0 0.0 17.6 13.7 0.0 11.1 15.6 6.3 0.0 0.0 0.0 12.5 13.0 5.5 0.0 12.3 12.6 12.4 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 20.7 0.0 0.0 0.0 0.0 10.2 0.0 0.0 1.6 0.0 0.0 18.6 12.4 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 16.0 4.3 13.5 0.0 0.0 AC009779.3 ENSG00000258311 "Novel protein" 12 55716036-55724703 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.1;Club cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 11.4" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.10e-3)" "unprognostic (9.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-2)" "unprognostic (7.25e-2)" "unprognostic (4.89e-3)" "unprognostic (2.23e-2)" "unprognostic (1.34e-2)" "unprognostic (2.48e-2)" "unprognostic (2.55e-2)" "unprognostic (1.17e-2)" "unprognostic (3.04e-3)" "unprognostic (3.73e-1)" "unprognostic (7.46e-2)" "unprognostic (4.05e-3)" "unprognostic (2.56e-1)" 15.4 2.6 3.6 2.9 4.4 4.6 9.3 4.1 4.0 3.1 3.4 7.5 4.2 3.1 3.1 3.0 4.3 1.9 13.7 3.6 3.5 3.7 12.3 2.8 3.0 4.5 4.1 4.6 2.2 0.9 3.4 1.0 4.2 4.5 4.2 10.1 3.0 1.4 14.4 4.3 7.0 4.8 3.6 6.3 4.0 3.6 4.0 1.4 3.9 6.1 2.5 4.1 2.9 5.5 1.1 0.8 3.3 1.2 4.4 6.7 1.9 2.0 0.9 1.5 1.1 1.6 5.8 4.9 1.1 1.5 1.2 2.4 1.8 0.3 1.1 4.6 3.7 1.9 3.0 1.8 0.4 2.3 2.1 2.8 1.0 5.9 0.2 8.8 0.4 4.6 2.9 3.8 3.9 1.1 1.1 1.3 3.7 0.9 0.6 1.7 2.5 0.8 0.0 1.1 3.1 4.1 1.3 0.4 2.4 1.9 2.1 3.4 2.1 3.9 3.7 2.0 0.7 3.0 4.0 3.4 11.4 1.3 2.1 2.7 0.6 1.3 0.5 0.5 0.4 0.6 0.2 0.2 0.5 1.0 0.2 0.3 1.7 0.4 2.0 0.6 0.0 0.6 3.6 4.4 4.1 4.0 3.6 3.5 4.5 4.1 4.2 3.6 4.0 5.5 0.1 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 AC139530.2 ENSG00000262660 "Novel protein" 17 81703371-81720539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.4;skeletal muscle: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.5;Karpas-707: 6.8;MOLT-4: 18.0;SK-BR-3: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043, HPA023048" Approved Supported Mitochondria NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100, HPA023048: AB_2301950" "unprognostic (2.36e-3)" "unprognostic (1.17e-1)" "unprognostic (2.87e-1)" "unprognostic (3.83e-1)" 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.3 0.6 1.6 5.5 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.3 0.5 0.9 0.3 0.0 1.6 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.5 0.6 0.2 0.1 0.0 6.8 0.0 0.8 18.0 0.8 1.0 0.7 0.0 3.9 0.6 1.4 0.0 0.0 3.3 1.5 0.0 6.6 1.8 0.4 3.2 1.5 0.0 0.5 1.1 1.1 1.8 0.6 0.0 0.7 1.4 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 850.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 98000 "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: AB_1844478, HPA020595: AB_1844479" "unprognostic (4.81e-2)" "unprognostic (2.86e-1)" "unprognostic (2.21e-2)" "unprognostic (1.09e-2)" "unprognostic (6.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (6.87e-4)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (2.84e-3)" 197.9 405.2 120.1 78.7 131.0 103.5 142.9 128.4 126.7 110.5 170.6 157.3 306.2 98.5 44.4 181.0 94.0 92.6 576.8 117.8 125.0 215.3 517.4 106.7 52.0 127.5 125.3 80.9 236.5 159.6 189.6 112.0 124.8 133.2 131.6 34.9 158.5 113.9 850.4 135.7 270.6 110.6 118.2 132.2 186.4 75.9 132.0 83.4 159.3 817.1 82.9 137.1 115.3 122.7 193.7 162.5 65.8 92.4 271.2 99.2 135.9 156.5 169.0 136.9 84.5 67.2 155.3 90.4 109.0 260.0 49.7 147.9 43.8 135.5 119.6 295.9 47.1 50.6 120.9 101.1 131.2 49.0 129.5 112.5 122.0 114.7 178.5 212.6 124.8 111.3 73.3 110.2 222.7 65.3 49.6 68.4 34.3 178.4 91.9 70.4 78.3 227.2 305.1 155.0 19.1 47.3 206.8 224.8 110.8 60.6 102.8 74.9 151.5 127.5 101.6 75.9 149.9 104.5 59.1 5.2 230.7 85.7 94.9 24.2 96.1 121.3 39.1 57.8 35.7 25.2 32.5 43.8 99.9 24.6 23.7 29.1 20.2 37.8 39.3 80.4 31.8 79.4 120.1 131.0 128.4 126.7 117.8 125.0 127.5 125.3 124.8 118.2 132.0 122.7 109.9 60.9 81.9 143.3 72.3 87.3 336.0 322.4 91.6 42.0 157.7 104.5 451.4 138.7 206.7 202.3 62.6 482.9 87.7 484.2 185.9 310.8 133.0 87.2 52.7 77.4 179.3 65.2 40.9 77.0 197.8 118.6 406.7 88.5 88.4 121.1 53.6 365.4 182.4 33.7 33.4 251.8 233.9 67.9 94.6 249.9 124.5 101.5 81.8 34.7 274.9 40.7 73.2 23.1 24.5 106.1 388.9 132.8 172.3 369.0 489.8 345.8 144.1 41.3 105.2 88.3 147.4 114.3 47.8 113.8 87.5 663.3 75.5 169.2 316.8 367.5 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007940-33080996 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 440.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018479, CAB079913" Approved Approved Mitochondria NA NA 1100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB079913: AB_2546087, HPA018479: AB_1844676" "prognostic favorable (4.37e-4)" "unprognostic (3.25e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (7.86e-3)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (4.95e-2)" "unprognostic (8.33e-3)" "unprognostic (9.56e-3)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-3)" 85.3 88.6 39.9 76.9 45.0 74.3 80.4 44.1 49.0 79.6 49.8 117.2 140.0 58.6 52.1 108.5 65.3 49.0 114.1 38.8 43.8 181.6 172.9 59.3 73.3 48.5 42.8 59.9 78.9 123.6 49.4 68.4 50.4 63.2 114.0 51.0 81.1 55.5 154.2 74.4 139.4 68.1 44.0 57.2 92.7 54.8 44.3 85.9 86.6 122.9 113.4 84.2 76.9 49.3 339.1 153.4 131.6 149.7 94.9 116.6 132.8 185.0 143.5 267.7 280.2 283.2 311.9 602.1 218.4 139.8 204.2 235.4 312.5 327.0 276.6 261.6 229.3 396.2 270.0 219.9 218.2 712.5 222.2 118.1 238.2 232.7 471.2 163.3 190.2 245.7 436.9 230.4 165.0 174.2 273.0 392.8 181.2 337.4 222.4 314.7 222.2 415.6 286.2 205.1 190.8 114.8 205.4 235.0 584.8 151.4 194.5 517.2 138.9 165.5 194.3 259.4 357.5 238.0 324.7 565.7 232.4 664.6 195.5 49.2 158.8 198.0 77.1 145.5 81.8 122.3 72.7 74.0 195.8 105.8 72.9 67.9 42.1 115.3 130.4 154.2 96.8 188.1 39.9 45.0 44.1 49.0 38.8 43.8 48.5 42.8 50.4 44.0 44.3 49.3 60.5 51.3 79.0 19.6 44.0 125.2 101.4 228.1 63.7 21.1 66.5 72.6 106.9 71.4 142.8 112.2 83.4 158.0 37.0 109.6 256.3 120.2 108.3 50.0 42.1 70.7 50.4 50.9 16.2 123.7 164.6 58.0 66.3 47.0 40.0 38.8 41.4 135.5 96.1 8.4 19.7 84.7 89.5 44.8 60.1 42.8 46.9 48.4 87.2 12.2 67.3 22.1 48.4 14.1 22.0 110.5 67.2 44.0 55.7 109.0 236.9 440.0 67.0 41.8 52.6 34.1 108.4 91.0 31.6 88.6 122.7 216.6 40.7 72.2 122.6 120.5 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709556-4742043 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 485.4;HEL: 273.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria NA NA 31000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA063324: AB_2684985" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favorable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 75.5 62.9 30.1 23.7 36.9 20.1 39.7 33.5 34.9 41.0 56.2 67.4 68.3 41.9 31.2 61.2 34.4 35.9 100.6 27.0 40.6 101.4 199.9 34.9 29.6 32.8 38.1 47.8 38.9 66.8 22.2 35.1 33.7 49.2 59.6 16.8 38.7 42.6 242.8 47.4 62.5 41.7 33.5 33.0 69.5 11.2 37.9 35.1 49.9 159.6 34.4 48.7 39.7 36.5 44.1 30.7 55.5 22.6 75.3 55.5 4.9 60.4 116.1 30.4 45.5 5.7 43.6 39.5 20.4 63.5 16.6 29.3 40.8 48.0 51.2 485.4 37.1 273.3 56.1 91.3 58.5 28.7 14.1 87.9 41.4 26.4 36.0 70.4 91.2 38.2 22.1 49.6 91.8 22.5 27.5 65.6 53.3 77.1 15.4 38.2 21.1 19.2 82.1 55.7 98.3 63.6 65.7 18.5 35.1 53.7 26.5 53.2 65.9 25.7 28.8 70.1 43.6 15.5 10.5 50.3 46.9 19.9 18.9 13.3 10.2 32.2 27.6 8.1 25.5 12.1 21.6 25.7 19.6 12.3 28.4 29.2 2.8 27.4 6.5 26.3 31.8 21.1 30.1 36.9 33.5 34.9 27.0 40.6 32.8 38.1 33.7 33.5 37.9 36.5 58.3 57.7 80.3 78.0 34.0 74.2 76.4 87.4 84.2 10.7 58.8 28.3 182.9 68.6 71.0 66.2 22.9 95.5 34.6 129.9 258.2 84.8 3.7 40.7 30.6 65.7 109.6 68.1 23.4 69.6 17.0 83.4 87.1 37.8 46.2 75.8 79.2 305.6 47.5 15.2 55.8 104.2 73.2 46.9 41.4 4.5 108.7 34.7 74.7 22.5 40.9 28.2 33.0 44.7 87.0 67.3 78.7 149.7 62.8 166.7 111.8 183.5 52.8 11.0 105.2 76.0 60.8 6.4 14.1 152.5 104.4 214.0 36.4 68.5 145.5 151.6 AL355315.1 ENSG00000249967 "Novel protein" 10 97584374-97673910 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "tongue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.2;EFO-21: 1.3;GAMG: 1.0;HBEC3-KT: 1.1;hTERT-RPE1: 1.9" HPA076857 Uncertain "Plasma membrane" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Plasma membrane" "HPA076857: AB_2686817" 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.2 0.0 0.4 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 1.3 0.2 1.0 0.7 0.0 1.1 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.2 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALS2 ALS2CR6 ENSG00000003393 "Alsin Rho guanine nucleotide exchange factor ALS2" Q96Q42 2 201700267-201782112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.8;granulocytes: 46.9;Inhibitory neurons: 66.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 26.4" "Group enriched" "Detected in many" 5 "basophil: 23.0;eosinophil: 6.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 23.0" "Cell line enhanced" "Detected in all" "HMC-1: 50.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 87.8" HPA046588 Enhanced Approved "Intermediate filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments, Cytosol" "HPA046588: AB_2679709" "unprognostic (3.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-3)" "unprognostic (2.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.04e-3)" "unprognostic (9.17e-2)" "unprognostic (4.16e-2)" "unprognostic (1.52e-1)" "unprognostic (2.99e-1)" "unprognostic (2.83e-2)" "unprognostic (1.09e-2)" "unprognostic (1.88e-1)" "unprognostic (1.61e-1)" "unprognostic (2.10e-1)" "unprognostic (1.84e-1)" 7.3 5.5 2.6 2.6 3.1 5.6 6.8 26.4 4.2 6.4 4.5 6.6 3.2 6.6 7.8 4.8 6.4 3.8 13.7 3.4 1.6 8.0 14.5 6.7 2.8 0.9 1.0 6.0 5.7 4.3 10.0 3.5 1.7 6.1 3.4 5.4 5.4 1.6 13.5 7.1 6.6 4.8 0.3 5.3 6.8 5.3 1.4 2.4 6.3 5.9 2.8 6.2 5.7 2.6 6.5 6.7 7.1 5.6 7.0 5.1 7.2 8.6 10.4 14.0 13.2 5.8 8.4 1.2 3.8 11.7 6.1 3.7 4.6 10.6 18.0 3.5 4.8 15.3 6.2 5.2 8.1 16.4 50.4 9.8 4.1 11.5 14.0 5.7 10.0 8.6 9.8 5.7 9.6 7.5 6.7 20.3 9.2 4.6 5.3 5.4 7.7 4.2 9.8 8.8 3.4 7.8 6.4 7.1 9.2 14.3 5.4 7.2 7.9 11.6 7.2 3.5 6.2 7.1 9.2 4.5 8.5 3.4 7.2 23.0 0.9 6.8 1.6 1.7 1.9 1.2 1.3 1.3 1.4 1.0 1.5 1.5 0.9 3.0 1.2 0.8 2.1 0.8 2.6 3.1 26.4 4.2 3.4 1.6 0.9 1.0 1.7 0.3 1.4 2.6 7.6 12.8 16.7 28.7 2.8 5.4 3.8 4.4 3.4 15.1 5.4 4.3 32.3 8.6 4.3 9.2 29.2 5.7 3.7 3.6 0.0 6.9 16.5 14.0 6.8 10.4 4.8 12.0 91.8 3.3 3.2 6.9 9.7 6.8 46.9 10.1 13.2 20.3 5.9 8.4 66.6 6.9 2.0 3.2 3.0 6.5 7.8 4.8 0.0 27.2 3.1 5.9 4.1 36.2 44.0 6.1 3.9 8.2 2.3 4.4 7.8 6.1 17.5 15.4 0.0 9.3 8.4 7.3 5.6 4.6 6.0 6.7 3.9 5.2 4.7 3.7 ANAPC16 "APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728" ENSG00000166295 "Anaphase promoting complex subunit 16" Q96DE5 10 72216000-72235860 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 93.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037815 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA037815: AB_10672288" "unprognostic (2.87e-1)" "unprognostic (4.35e-3)" "unprognostic (2.01e-2)" "unprognostic (7.12e-3)" "unprognostic (2.16e-1)" "unprognostic (6.20e-3)" "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (3.10e-2)" "unprognostic (1.90e-2)" "unprognostic (2.11e-1)" "unprognostic (2.75e-3)" "unprognostic (7.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" 20.5 25.2 12.4 15.0 13.4 14.1 21.9 16.6 15.2 19.7 15.5 23.6 15.7 18.2 22.3 14.9 23.5 12.6 43.6 12.5 12.8 24.2 27.2 18.9 25.4 13.6 12.8 24.3 33.7 33.1 15.9 11.9 13.4 21.5 17.9 20.6 32.3 21.8 62.7 15.0 19.6 17.8 12.4 22.7 25.8 8.4 13.1 32.3 23.5 43.2 25.7 19.5 15.1 14.6 24.9 12.1 12.1 14.3 33.0 15.7 9.3 8.5 17.3 11.7 11.0 14.6 31.1 24.3 13.6 12.7 14.1 19.0 10.9 21.9 11.0 29.0 18.0 12.5 10.6 14.4 39.6 21.0 14.7 20.5 93.9 10.6 34.8 25.8 14.3 35.1 18.4 28.1 13.6 15.0 17.9 21.1 9.3 18.2 6.8 10.2 10.8 24.2 29.4 10.4 17.4 16.0 14.8 37.9 29.5 15.2 12.2 21.9 18.6 5.9 13.8 9.5 13.1 28.6 26.8 25.1 16.4 40.3 7.0 41.1 21.5 38.8 31.4 23.1 35.2 60.5 35.2 31.3 18.1 66.1 48.6 38.6 19.7 34.4 24.9 45.7 34.7 36.3 12.4 13.4 16.6 15.2 12.5 12.8 13.6 12.8 13.4 12.4 13.1 14.6 191.0 157.0 209.5 41.8 303.7 111.7 246.7 322.0 150.8 81.0 288.6 316.5 435.4 280.2 234.9 222.5 37.5 198.4 240.1 166.8 684.8 239.8 91.9 188.9 98.9 179.8 161.8 155.0 47.8 291.9 191.2 142.0 108.1 145.9 202.0 110.1 203.1 481.3 226.5 33.7 57.2 258.0 254.3 310.0 111.9 53.4 233.6 160.4 193.9 36.5 322.4 192.4 363.5 43.2 75.9 196.9 239.9 250.1 208.2 218.1 262.6 548.7 217.0 144.5 230.1 162.0 219.9 158.7 126.2 189.9 140.9 149.3 268.6 145.6 214.1 240.9 ANKRD13C "dJ677H15.3, DKFZP566D1346" ENSG00000118454 "Ankyrin repeat domain 13C" Q8N6S4 1 70258999-70354734 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 98.5;Inhibitory neurons: 91.0;Oligodendrocytes: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.34e-2)" "unprognostic (7.20e-2)" "unprognostic (3.05e-3)" "unprognostic (3.11e-1)" "unprognostic (1.28e-2)" "unprognostic (1.91e-2)" "unprognostic (6.38e-3)" "unprognostic (6.59e-2)" "unprognostic (3.48e-2)" "unprognostic (2.41e-1)" "unprognostic (2.28e-2)" "unprognostic (3.17e-2)" "unprognostic (1.47e-3)" "unprognostic (1.57e-3)" "unprognostic (1.28e-1)" "unprognostic (1.95e-1)" "unprognostic (7.42e-2)" 9.8 8.7 5.3 8.3 6.2 5.7 7.8 8.9 7.8 7.8 1.5 8.7 7.6 9.1 5.9 7.1 6.3 7.1 5.4 6.1 5.2 9.1 7.5 7.4 9.4 3.8 4.1 9.6 8.5 9.0 4.7 7.4 3.8 8.3 8.7 13.3 7.2 6.4 9.1 9.9 8.2 8.4 4.1 8.3 8.3 4.3 4.4 9.0 8.5 8.6 8.2 8.4 6.7 6.8 18.4 8.5 14.1 14.7 17.1 22.8 5.6 16.9 19.8 14.5 14.5 11.5 10.1 15.7 16.0 19.9 14.3 12.0 13.8 10.0 17.1 22.6 15.8 17.0 19.5 10.7 18.0 18.8 8.7 19.6 11.1 16.7 15.2 12.9 14.0 8.4 14.4 22.2 14.4 8.3 11.1 8.3 15.2 8.4 16.2 11.5 17.8 10.9 20.5 11.9 11.1 11.1 21.7 26.6 23.7 13.5 14.0 12.5 17.8 22.6 14.4 34.9 20.6 21.4 28.8 12.9 19.5 14.6 19.2 14.6 7.0 8.6 8.8 9.1 12.4 9.8 11.1 11.0 10.6 8.5 10.3 9.7 0.7 8.4 8.0 5.6 14.0 9.1 5.3 6.2 8.9 7.8 6.1 5.2 3.8 4.1 3.8 4.1 4.4 6.8 15.1 28.9 15.1 40.1 17.0 16.2 11.4 7.9 15.9 19.3 10.6 7.5 12.3 5.7 14.1 11.0 31.3 8.9 17.0 12.9 13.7 10.0 1.7 11.9 20.3 13.2 12.5 5.5 98.5 10.5 10.9 18.7 20.4 15.1 3.8 9.4 12.5 7.2 10.3 6.7 91.0 9.5 12.2 12.9 7.8 2.1 11.8 11.7 17.8 43.1 10.5 10.9 13.4 64.8 103.6 13.0 10.6 11.3 16.6 14.9 5.9 13.2 15.7 23.5 0.0 18.3 17.7 8.5 6.2 13.3 12.1 13.1 20.3 18.0 10.3 15.9 ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21799934-22283357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 24.9;parathyroid gland: 17.0;skeletal muscle: 65.5;tongue: 50.4" "Group enriched" "Detected in many" 7 "Astrocytes: 67.9;Cardiomyocytes: 86.2;Excitatory neurons: 166.6;Inhibitory neurons: 136.4;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;HAP1: 5.0;HEK 293: 6.6;NTERA-2: 3.5;RPTEC TERT1: 3.2;U-266/84: 3.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058857: AB_2683835" "unprognostic (5.25e-3)" "unprognostic (1.36e-3)" "unprognostic (2.43e-1)" "unprognostic (7.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.85e-2)" "unprognostic (8.17e-3)" "unprognostic (2.30e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.54e-4)" "unprognostic (8.55e-2)" "prognostic favorable (2.50e-7)" "unprognostic (3.65e-3)" "unprognostic (2.84e-1)" "unprognostic (2.77e-4)" "unprognostic (7.94e-2)" 0.9 4.5 1.9 0.8 3.0 0.0 0.7 0.1 8.9 1.6 3.0 2.6 3.3 1.5 1.3 2.0 0.8 1.7 24.9 4.0 2.2 3.6 2.1 1.2 0.2 2.7 2.1 0.5 3.9 17.0 3.4 0.0 2.2 4.2 3.3 2.1 2.6 4.1 65.5 0.1 2.5 2.7 0.4 0.7 3.0 1.8 2.4 0.2 4.7 50.4 0.3 2.0 0.3 3.4 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.3 1.4 2.5 0.0 0.0 0.0 0.0 3.5 2.6 0.0 0.0 0.0 0.0 3.2 0.1 2.7 2.6 0.0 0.0 0.0 2.1 2.1 1.9 0.0 0.0 1.9 0.0 0.0 2.0 3.7 0.0 2.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.1 8.9 4.0 2.2 2.7 2.1 2.2 0.4 2.4 3.4 0.4 0.0 5.9 67.9 0.6 0.3 0.3 0.0 0.0 6.7 2.2 0.6 86.2 1.5 0.0 1.8 0.0 0.1 0.0 7.8 1.9 1.3 5.8 0.4 0.2 3.2 5.4 0.4 166.6 2.7 0.0 3.0 1.5 0.3 0.0 3.0 2.5 5.1 0.5 1.7 136.4 7.1 0.0 0.6 1.4 2.9 0.0 1.6 1.8 14.0 1.9 2.8 0.0 81.4 4.2 1.0 4.4 1.2 0.0 1.4 2.7 3.3 0.7 0.8 0.0 8.1 2.4 11.0 0.9 0.1 0.1 0.0 0.2 1.6 4.6 0.2 ANXA11 ANX11 ENSG00000122359 "Annexin A11" P50995 10 80150889-80205572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 443.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004851, HPA027545" Supported Supported Nucleoplasm,Cytosol NA NA 210000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB004851: AB_626682, HPA027545: AB_1844851" "unprognostic (1.85e-2)" "unprognostic (2.85e-2)" "unprognostic (5.35e-3)" "unprognostic (5.06e-2)" "unprognostic (8.18e-3)" "unprognostic (1.99e-1)" "unprognostic (4.01e-3)" "unprognostic (6.28e-2)" "unprognostic (2.32e-2)" "unprognostic (4.88e-2)" "unprognostic (3.46e-2)" "unprognostic (2.56e-2)" "prognostic favorable (6.69e-8)" "unprognostic (2.69e-3)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (2.02e-1)" 139.9 29.5 39.0 99.4 40.6 192.9 107.6 27.5 46.8 86.6 52.8 130.3 138.0 74.3 107.5 210.2 109.0 84.8 236.2 47.3 29.0 144.7 47.7 109.5 81.2 26.4 26.6 78.2 95.4 81.8 27.2 91.1 23.9 100.3 120.7 4.8 94.1 81.8 188.9 75.6 137.2 86.0 25.4 76.2 139.3 24.5 24.6 100.2 61.4 166.2 101.7 148.1 102.8 30.4 221.7 195.7 10.4 53.9 220.2 201.1 119.6 149.5 397.3 95.7 98.8 168.7 338.2 13.1 113.6 236.7 8.1 277.7 44.6 136.2 54.2 384.3 76.0 84.4 98.9 131.5 129.4 92.0 212.3 222.9 74.6 57.8 39.4 178.9 143.9 117.9 82.1 163.7 76.8 127.3 119.8 200.9 19.6 211.5 367.7 91.7 14.9 344.0 155.1 191.8 5.1 37.9 65.0 269.9 156.4 83.4 80.6 120.6 160.0 68.7 101.4 157.6 84.4 91.7 145.6 96.0 66.6 155.4 47.4 130.8 66.8 443.8 72.9 52.4 75.0 64.9 92.5 100.5 49.4 54.2 83.7 74.4 231.8 61.3 59.1 78.5 126.5 85.4 39.0 40.6 27.5 46.8 47.3 29.0 26.4 26.6 23.9 25.4 24.6 30.4 150.5 96.1 78.4 17.3 101.4 51.2 266.4 219.4 92.8 1.6 58.8 50.4 293.3 203.0 227.1 220.7 0.0 271.7 137.1 457.7 332.6 429.2 4.5 180.6 49.7 82.7 77.5 29.9 29.5 352.5 309.8 113.1 175.8 265.7 116.1 81.4 91.4 40.8 228.1 3.3 15.5 186.9 97.6 149.7 167.4 9.6 92.9 155.0 90.7 24.4 208.2 38.9 159.6 3.0 2.3 420.6 461.0 92.6 98.2 414.9 367.7 156.8 229.0 2.8 92.1 56.4 137.9 2.8 51.5 98.4 42.1 185.5 131.9 50.8 227.8 581.4 ANXA7 ANX7 ENSG00000138279 "Annexin A7" P20073 10 73375101-73414076 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 693.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004312, HPA064290" Approved Uncertain Nucleoplasm,Cytosol NA NA 290000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "CAB004312: AB_626681, HPA064290: AB_2685233" "unprognostic (1.48e-1)" "unprognostic (4.70e-2)" "unprognostic (1.90e-1)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (2.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (6.93e-2)" "unprognostic (3.06e-2)" 79.0 72.1 60.1 58.6 61.1 85.2 75.5 55.9 67.8 69.9 57.1 64.3 39.4 57.6 80.5 69.3 57.0 51.8 113.4 62.6 64.8 116.4 126.0 60.4 60.8 55.4 57.0 67.1 55.9 240.7 55.6 57.2 58.1 69.2 74.4 32.3 70.2 70.6 200.1 61.2 44.9 68.4 60.8 53.4 51.7 26.3 62.5 55.4 83.1 139.6 84.1 75.2 57.4 63.9 143.4 101.4 38.8 95.3 148.9 145.2 84.3 93.2 244.7 119.9 100.6 149.2 164.8 56.6 92.2 177.2 78.8 116.9 73.2 110.9 118.1 140.8 54.5 80.4 46.5 133.9 130.6 115.7 35.4 90.8 105.7 149.2 265.1 104.7 108.0 60.8 106.2 156.4 154.4 114.5 66.1 74.4 43.5 85.1 693.9 53.9 110.1 103.4 209.3 86.5 30.9 42.8 105.1 239.4 90.3 54.3 149.7 61.0 100.8 48.5 87.9 148.1 122.5 100.5 153.2 79.5 114.4 147.4 38.4 188.6 98.1 129.8 57.5 74.9 78.9 96.5 88.8 72.2 101.3 75.1 80.0 71.4 98.0 97.2 77.5 43.2 127.8 137.2 60.1 61.1 55.9 67.8 62.6 64.8 55.4 57.0 58.1 60.8 62.5 63.9 85.0 67.3 61.8 24.8 68.4 86.2 137.9 189.8 40.9 33.0 56.7 40.9 131.9 62.9 120.6 93.8 14.6 210.6 61.2 76.2 193.7 167.2 9.7 82.9 43.8 82.4 191.8 119.3 44.8 150.9 112.0 85.3 51.5 60.4 108.3 69.0 56.4 122.7 119.9 10.1 50.7 82.8 193.3 83.0 87.3 6.5 137.0 91.4 85.4 15.0 301.5 66.4 36.0 26.7 46.2 133.1 47.5 174.5 73.0 125.3 57.9 262.8 161.1 26.3 26.3 82.1 92.9 24.0 42.3 72.5 92.5 177.3 78.4 46.9 76.9 146.1 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 AP4E1 "AP-4-EPSILON, SPG51" ENSG00000081014 "Adaptor related protein complex 4 subunit epsilon 1" Q9UPM8 15 50908672-51005895 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041749, HPA041891" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 59: Non-specific - Transcription" "HPA041749: AB_10794490, HPA041891: AB_10796462" "unprognostic (1.72e-2)" "unprognostic (3.44e-1)" "unprognostic (9.21e-2)" "unprognostic (2.22e-3)" "unprognostic (1.27e-1)" "unprognostic (9.46e-2)" "unprognostic (6.83e-3)" "unprognostic (1.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (6.84e-2)" "unprognostic (3.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" "unprognostic (2.03e-2)" 3.7 3.0 2.5 4.4 2.9 3.1 3.0 3.3 2.7 3.7 3.2 3.6 3.0 4.3 2.1 4.7 3.2 2.6 3.9 2.4 2.6 2.8 2.9 3.1 5.5 2.9 2.8 2.9 2.2 5.1 2.4 4.7 2.9 2.7 3.4 3.8 3.3 2.6 8.2 5.4 3.2 4.5 2.6 4.6 2.9 3.9 3.0 6.5 3.8 6.3 4.7 4.0 4.1 3.5 11.5 8.7 6.0 7.1 7.9 12.0 11.7 11.1 8.9 10.7 11.1 10.7 1.8 11.2 4.3 12.5 10.8 13.7 9.0 9.6 12.4 12.3 4.6 9.8 14.5 4.3 11.1 12.1 8.2 12.2 11.6 13.4 21.0 6.6 7.2 8.8 9.1 6.3 14.7 15.4 7.1 6.9 3.9 5.2 4.4 9.7 8.5 6.9 7.9 10.4 4.1 6.7 11.8 8.4 8.7 10.7 7.6 11.7 10.0 15.7 5.8 9.5 15.9 9.6 11.7 14.1 12.3 26.1 7.3 2.7 0.6 0.3 0.8 0.9 0.5 0.5 0.6 0.7 0.6 0.3 0.4 0.9 0.1 0.5 0.5 0.4 0.3 0.4 2.5 2.9 3.3 2.7 2.4 2.6 2.9 2.8 2.9 2.6 3.0 3.5 6.6 6.4 6.1 17.6 8.7 5.7 1.5 3.8 4.0 9.8 4.9 3.7 10.4 2.8 8.4 5.5 18.8 7.3 7.7 7.9 0.0 4.9 2.0 5.9 10.0 7.8 3.0 6.9 26.7 4.8 5.7 4.7 7.1 6.2 10.2 7.2 6.8 8.1 7.2 8.4 27.0 5.3 2.0 17.0 4.1 1.4 5.9 10.2 1.8 25.3 6.5 3.9 8.2 19.1 36.0 10.6 2.4 4.1 9.6 2.2 6.2 3.6 4.8 11.2 6.6 7.1 6.6 10.2 7.7 6.6 7.0 7.3 9.6 4.8 5.5 2.4 AP5M1 "C14orf108, FLJ10813, mu5, MuD, MUDENG" ENSG00000053770 "Adaptor related protein complex 5 subunit mu 1" Q9H0R1 14 57268924-57298742 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055768, HPA057098" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA055768: AB_2682913, HPA057098: AB_2683335" "unprognostic (7.95e-2)" "unprognostic (5.37e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.52e-1)" "unprognostic (2.68e-1)" "unprognostic (2.27e-2)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-1)" "unprognostic (5.51e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.11e-14)" "unprognostic (6.26e-2)" "unprognostic (1.38e-1)" "unprognostic (6.62e-2)" "unprognostic (1.60e-1)" 11.5 12.1 6.5 13.2 8.7 15.4 13.8 11.9 10.2 14.3 20.1 25.7 28.8 11.7 15.3 16.3 9.8 12.1 16.5 7.2 13.5 28.5 21.1 11.7 17.0 13.2 9.0 8.3 10.0 31.5 6.6 11.0 12.1 12.3 29.5 22.5 16.7 12.6 15.5 11.2 25.2 14.0 9.0 14.4 14.9 10.5 10.0 22.2 18.4 28.3 22.8 13.3 7.5 11.0 19.0 16.1 22.3 21.5 20.2 22.6 17.8 21.0 20.7 18.5 24.5 16.1 27.8 26.7 20.4 20.7 16.5 27.6 32.1 18.5 27.8 27.9 9.4 14.8 15.3 18.7 14.0 44.9 23.6 20.9 23.8 17.6 13.3 19.2 21.0 23.2 18.4 17.6 29.8 16.6 41.6 11.2 16.9 34.6 22.4 27.9 29.4 20.3 42.7 44.1 36.4 20.0 24.3 38.9 16.3 21.8 23.8 20.4 13.5 26.3 24.9 13.9 12.0 9.7 15.9 24.1 23.2 21.1 19.8 20.5 17.8 36.4 19.1 15.4 20.8 22.8 21.0 22.0 24.9 15.9 21.4 22.9 14.9 28.6 15.3 13.2 25.6 17.9 6.5 8.7 11.9 10.2 7.2 13.5 13.2 9.0 12.1 9.0 10.0 11.0 15.4 32.1 13.1 19.2 30.7 20.1 18.8 30.5 21.6 21.0 17.8 11.6 32.6 17.2 25.3 23.9 39.6 21.5 22.6 40.6 86.1 20.9 115.1 11.5 12.9 19.0 29.9 23.4 42.3 16.2 18.9 17.0 29.0 13.1 17.7 13.4 18.9 31.1 24.5 35.3 45.6 29.0 44.7 25.6 11.5 88.1 17.7 17.9 21.4 21.5 32.1 19.3 34.0 19.1 31.0 16.6 23.7 20.3 26.8 19.9 44.8 74.4 16.2 31.3 19.7 12.7 13.4 31.5 10.7 37.8 21.5 19.3 22.3 17.2 39.6 23.7 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674014-49683971 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 2300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 21.7 43.6 18.0 30.7 18.0 42.3 26.8 17.9 22.8 24.8 27.7 48.5 48.6 19.7 24.7 40.2 33.7 22.3 40.6 17.7 19.9 65.8 63.3 26.8 35.2 19.2 21.3 24.6 34.8 63.0 38.3 31.9 24.3 31.0 51.7 12.9 34.0 29.5 103.8 32.8 35.1 28.1 16.8 27.2 35.5 18.7 20.0 37.3 48.6 103.9 43.4 35.0 21.2 16.7 101.2 79.2 84.2 110.8 71.3 48.3 113.6 64.2 79.3 87.4 91.2 130.1 101.7 127.1 70.0 71.7 78.9 89.8 95.1 143.4 64.2 61.9 41.0 138.8 123.4 105.1 72.0 145.5 204.7 55.0 106.5 49.2 101.4 85.5 78.7 86.4 86.6 59.8 86.0 90.8 105.3 76.6 50.4 140.5 75.3 38.4 72.8 165.1 169.9 226.7 40.4 71.2 72.4 166.7 78.9 61.0 112.1 77.2 36.1 53.8 93.0 83.6 86.8 69.8 54.5 77.7 91.7 104.1 78.7 57.9 43.0 52.8 44.8 47.6 34.8 33.3 36.3 41.9 43.6 27.6 37.9 37.4 13.6 39.0 47.6 35.1 50.4 51.9 18.0 18.0 17.9 22.8 17.7 19.9 19.2 21.3 24.3 16.8 20.0 16.7 5.4 41.7 25.3 7.5 20.1 8.7 23.3 50.2 11.4 6.8 20.8 15.9 46.8 30.0 39.4 27.6 12.5 83.7 16.5 83.2 43.0 44.4 6.4 16.6 13.8 9.0 26.5 43.8 4.8 34.7 64.8 16.4 41.8 20.5 23.5 20.0 13.2 74.7 51.1 8.4 4.7 47.1 63.1 35.9 11.9 10.9 15.2 23.2 21.4 2.8 26.8 30.4 27.8 3.0 2.0 39.0 35.8 13.5 39.4 18.0 85.4 80.7 19.4 11.1 13.1 10.6 25.2 33.2 28.5 30.6 9.2 62.1 23.9 28.5 74.0 23.7 APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000612 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA000612: AB_1078594" "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" 5.9 6.5 2.8 3.7 3.2 3.7 6.6 3.6 5.2 4.3 5.4 5.9 5.9 4.4 4.7 6.2 5.1 4.0 11.5 4.2 3.9 11.2 14.5 4.3 3.3 4.5 4.3 4.1 6.0 11.6 3.2 4.1 4.6 5.9 6.5 6.8 5.8 4.4 17.8 6.7 4.6 5.9 2.9 3.5 6.8 2.2 4.6 3.6 8.3 17.9 3.5 4.2 4.0 4.3 11.4 6.5 6.0 8.2 16.9 11.7 6.4 7.4 6.9 6.2 6.0 7.0 6.3 8.3 6.9 8.4 11.7 8.8 18.3 7.0 9.3 8.4 8.0 8.8 10.2 7.2 11.0 17.5 9.1 11.8 11.8 10.4 18.4 7.2 8.8 10.7 15.2 10.7 10.8 6.1 7.2 7.1 4.9 6.8 12.1 7.9 14.6 8.6 7.8 8.3 0.6 9.8 14.1 12.7 8.8 6.4 7.7 8.3 9.2 8.5 8.3 17.5 8.6 6.9 24.4 7.1 10.9 12.4 7.3 2.4 2.0 0.6 1.9 2.8 1.7 2.1 1.7 1.4 2.1 1.9 2.1 2.0 0.4 1.2 2.5 2.6 1.0 1.0 2.8 3.2 3.6 5.2 4.2 3.9 4.5 4.3 4.6 2.9 4.6 4.3 16.7 16.0 19.1 25.8 10.7 5.6 13.3 5.3 6.2 26.7 16.8 11.9 45.4 15.7 7.7 20.2 14.6 15.3 9.3 10.6 13.7 18.1 0.2 17.0 15.4 13.0 37.1 14.9 32.3 14.0 11.3 13.9 17.3 17.4 21.5 18.3 15.0 51.6 12.0 21.9 26.2 15.3 4.1 15.2 2.3 0.8 13.7 11.4 0.0 21.5 9.5 13.6 8.2 30.2 36.2 17.5 14.6 15.4 8.7 19.6 15.6 43.7 7.6 16.8 19.7 19.3 16.9 3.1 8.2 11.5 3.4 19.4 6.6 16.8 15.4 17.8 ARL5A ARL5 ENSG00000162980 "ADP ribosylation factor like GTPase 5A" Q9Y689 2 151788984-151828492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 88.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 88.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA027002: AB_10601685" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (9.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (6.04e-2)" "unprognostic (4.59e-2)" "unprognostic (4.61e-3)" "unprognostic (2.47e-1)" "unprognostic (1.40e-1)" "unprognostic (2.95e-3)" "unprognostic (2.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (2.55e-1)" 20.4 20.9 13.1 13.1 14.9 11.8 19.7 17.1 12.4 14.7 12.1 17.6 22.1 14.1 7.3 23.9 14.6 17.2 35.8 12.8 18.5 25.1 22.4 20.0 20.3 18.5 14.7 15.3 15.9 17.9 7.5 23.6 17.3 17.2 16.6 17.6 15.5 13.6 32.5 28.8 20.5 18.0 17.7 14.6 17.7 6.3 14.4 17.5 29.6 36.5 24.6 18.3 11.2 18.8 20.2 20.2 29.0 25.7 20.9 35.6 39.1 34.7 26.8 24.8 30.0 59.5 24.7 66.9 36.4 37.2 18.6 12.8 34.6 26.7 40.0 40.4 31.6 73.6 21.9 77.8 28.8 74.0 39.5 27.9 39.3 34.0 36.4 33.3 34.7 41.1 55.7 78.0 26.5 23.4 63.1 29.3 36.8 24.7 21.5 28.5 40.1 27.6 35.7 33.6 13.0 27.0 21.1 21.8 29.5 34.3 17.0 44.0 28.5 19.6 24.1 18.8 37.7 39.3 47.6 64.6 34.7 50.4 34.7 88.3 7.9 8.9 6.9 6.1 6.5 11.0 6.1 8.6 11.2 15.2 6.6 5.1 3.8 7.4 4.7 6.7 7.9 4.5 13.1 14.9 17.1 12.4 12.8 18.5 18.5 14.7 17.3 17.7 14.4 18.8 18.1 57.7 38.6 28.7 104.3 138.7 122.6 120.7 64.3 62.6 24.4 12.6 109.8 91.5 60.6 14.7 14.6 84.3 46.2 44.3 45.0 55.3 11.9 15.3 17.2 62.9 75.6 66.3 29.8 59.9 153.1 79.6 51.5 12.1 48.2 17.9 77.8 76.6 128.0 116.1 31.9 64.3 126.1 135.8 154.7 13.8 74.6 82.9 81.8 51.5 97.5 64.1 132.8 34.7 23.8 52.6 44.1 82.4 160.7 167.4 166.8 42.9 60.3 61.9 72.3 85.9 60.4 72.6 65.0 103.9 163.7 143.0 63.6 9.2 72.7 135.9 ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 16 "Early spermatids: 987.5;Late spermatids: 1846.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 15.7 17.4 9.9 9.0 10.3 4.9 16.3 11.3 12.6 16.0 10.7 18.2 10.9 16.8 13.7 16.2 13.8 10.5 36.1 10.4 11.5 16.7 18.0 14.5 11.8 10.7 11.5 15.9 12.7 28.5 13.4 15.2 11.1 18.7 14.5 28.0 14.9 16.1 37.2 15.1 12.5 13.6 10.0 10.0 13.6 26.4 11.0 13.8 17.4 31.8 12.1 15.5 16.0 10.2 18.8 18.2 20.8 18.2 27.4 29.5 14.4 19.7 33.4 19.6 20.6 14.6 53.8 17.6 15.4 17.3 9.8 31.3 18.9 14.4 21.2 18.6 26.4 15.3 24.0 18.8 30.5 41.7 8.0 23.0 45.4 20.7 42.1 37.2 12.7 14.1 15.9 20.7 22.7 11.2 23.1 22.9 16.4 13.9 10.0 15.8 13.2 19.2 28.9 13.4 14.2 31.5 20.3 12.3 32.0 21.0 29.1 18.0 19.3 16.2 13.9 11.2 24.5 25.4 39.4 22.5 20.8 23.7 11.5 8.4 2.8 4.9 6.3 4.9 10.3 7.2 7.3 8.3 5.4 5.7 9.1 8.6 1.7 8.6 6.9 4.6 7.6 5.7 9.9 10.3 11.3 12.6 10.4 11.5 10.7 11.5 11.1 10.0 11.0 10.2 31.0 54.5 28.0 46.4 41.4 26.8 42.9 46.2 44.3 50.4 29.8 20.8 81.3 27.1 44.9 22.0 35.5 37.7 35.2 33.8 23.5 37.0 987.5 22.3 38.3 21.7 22.8 24.6 69.0 28.0 33.2 35.6 32.6 28.7 29.2 23.1 20.0 28.9 27.3 70.7 73.1 22.9 50.8 18.0 20.1 1846.8 35.8 25.1 32.0 37.5 16.1 59.6 23.7 58.8 52.7 39.0 25.2 47.0 32.3 42.3 20.5 29.5 44.8 54.8 59.2 29.5 43.8 77.2 29.8 34.6 30.1 88.4 40.0 34.8 23.7 54.6 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740424-121928492 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm NA NA 83000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA038444: AB_10672745, HPA057549: AB_2683463" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 10.1 11.7 8.1 8.5 8.5 7.4 10.4 7.3 9.2 12.1 17.3 13.5 11.4 10.6 8.4 10.7 9.0 10.4 22.2 8.4 11.0 18.2 18.2 9.5 9.5 6.7 7.3 10.0 6.2 15.4 4.8 11.0 7.5 12.7 14.6 15.6 7.8 10.0 18.3 6.7 11.1 11.7 7.4 10.4 8.8 13.3 10.6 13.0 16.0 15.4 10.6 12.7 6.6 8.7 13.0 19.5 15.4 15.0 15.1 16.8 12.3 12.0 24.0 13.1 13.2 23.6 19.1 16.1 9.5 14.3 8.8 16.1 14.5 14.2 16.3 20.3 13.1 5.8 8.8 31.1 15.5 26.7 13.4 11.9 15.2 13.8 32.0 19.3 18.7 9.0 7.8 29.4 14.5 7.9 14.0 15.2 7.5 19.6 11.4 13.1 18.1 10.6 23.4 11.2 4.8 19.4 17.2 12.9 28.2 11.3 8.9 9.2 19.2 8.2 7.0 12.5 21.1 28.0 33.6 12.0 12.6 20.6 7.4 12.8 3.8 6.1 5.3 4.5 6.3 4.5 5.0 5.3 3.4 4.2 5.5 5.6 2.3 5.1 3.5 4.8 6.7 4.0 8.1 8.5 7.3 9.2 8.4 11.0 6.7 7.3 7.5 7.4 10.6 8.7 23.0 9.6 22.0 76.4 17.3 8.4 12.8 9.4 24.5 31.3 17.5 14.6 75.6 11.5 12.7 20.2 12.5 7.2 20.9 42.8 17.6 11.3 6.5 15.8 19.4 19.3 22.1 16.2 100.5 13.3 10.5 25.0 29.6 16.4 12.6 13.5 20.0 26.6 10.0 23.5 93.8 17.7 10.2 14.8 7.2 7.7 20.5 23.6 14.2 74.0 12.8 21.7 27.8 137.7 220.4 15.6 18.3 25.9 24.8 21.0 19.5 39.4 11.5 35.8 0.0 23.4 21.1 26.9 40.2 30.7 17.5 8.6 17.9 29.1 16.8 16.6 ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Microtubules "Actin filaments" "HPA036374: AB_10672354, HPA064759: AB_2685346" "prognostic unfavorable (1.36e-5)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (2.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-2)" "unprognostic (4.09e-1)" "unprognostic (1.03e-3)" "unprognostic (7.53e-2)" "unprognostic (2.98e-1)" "unprognostic (5.02e-3)" "unprognostic (1.20e-2)" 8.1 8.5 4.9 7.8 5.2 9.1 7.7 5.2 6.1 7.6 10.4 12.1 12.8 4.7 11.6 8.9 5.6 7.7 11.8 4.7 5.2 14.1 18.1 8.9 8.2 5.3 5.0 2.8 17.2 12.4 6.1 8.0 5.4 5.9 13.1 5.7 13.0 7.1 18.5 5.8 11.4 7.7 5.0 7.7 11.2 2.4 5.7 11.2 11.4 18.6 11.1 8.9 5.1 5.4 13.0 6.5 4.1 7.8 38.2 13.2 5.1 17.5 11.2 9.1 10.6 5.3 6.9 14.0 15.7 14.0 14.5 6.0 11.9 13.0 13.5 24.1 12.9 6.0 10.3 3.7 8.4 13.0 18.8 13.4 13.9 11.1 4.8 8.4 84.9 19.5 18.5 43.5 16.6 12.8 12.1 11.9 7.8 23.6 18.4 8.2 6.9 20.3 13.2 11.3 5.9 4.5 11.2 13.9 7.9 12.4 7.0 11.5 24.0 5.7 2.6 19.1 9.8 20.2 24.0 15.1 11.1 14.6 8.1 28.1 7.8 15.1 11.7 11.3 8.4 9.2 8.9 11.4 10.6 9.9 7.1 12.0 2.4 12.3 7.8 5.4 10.3 8.7 4.9 5.2 5.2 6.1 4.7 5.2 5.3 5.0 5.4 5.0 5.7 5.4 13.6 3.2 10.3 9.1 8.1 5.1 4.9 13.5 2.8 3.2 7.0 4.6 17.4 7.2 12.8 5.5 4.2 6.2 12.4 19.1 27.4 9.6 7.0 10.6 7.4 12.9 6.7 36.7 7.9 17.9 7.5 4.6 8.2 6.0 3.8 3.3 9.7 15.4 9.0 1.7 8.4 9.0 30.5 4.1 3.6 10.0 2.8 7.3 14.2 4.7 6.7 10.3 18.6 7.1 11.6 16.6 8.0 7.5 23.5 5.6 14.7 24.7 17.2 5.0 0.0 4.5 6.9 2.4 3.9 5.9 5.3 10.4 12.0 6.2 5.6 7.3 ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1760.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 784.3;Distal tubular cells: 1173.9;Extravillous trophoblasts: 463.0;Proximal tubular cells: 939.6;Syncytiotrophoblasts: 578.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported Mitochondria NA NA 8800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB013067: AB_221511, HPA040622: AB_2677048, HPA044202: AB_2678855" "unprognostic (3.08e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-2)" "unprognostic (3.54e-1)" "unprognostic (6.36e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (6.79e-2)" "unprognostic (8.31e-2)" "unprognostic (4.79e-2)" "unprognostic (7.30e-3)" "unprognostic (1.50e-2)" "prognostic favorable (1.22e-15)" "unprognostic (4.60e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (4.87e-3)" 251.3 453.6 198.6 177.7 209.2 210.5 260.4 233.0 251.4 195.5 401.9 414.0 438.9 192.6 225.6 362.6 227.2 146.3 1498.3 207.7 246.0 730.4 441.6 175.1 223.7 234.6 237.8 211.1 299.9 868.5 277.4 201.7 226.0 211.4 419.8 465.4 307.4 265.9 1602.0 290.3 335.0 233.0 205.4 226.8 419.1 167.6 226.7 277.3 261.4 1760.3 337.6 244.9 224.7 209.6 355.2 353.0 459.6 434.3 546.0 601.8 508.6 399.5 562.4 601.0 522.8 532.7 271.9 833.2 238.9 487.4 322.3 641.7 801.1 614.1 556.4 373.0 450.3 551.7 413.3 667.2 357.1 1182.7 501.6 559.2 422.3 434.6 448.2 481.3 630.4 442.5 454.0 477.2 521.8 367.6 612.8 579.7 432.3 344.5 367.6 596.5 533.8 1131.4 816.2 849.7 465.7 434.7 293.3 361.5 506.9 428.6 466.3 679.3 370.4 328.7 282.7 174.9 354.9 542.5 501.5 533.0 328.1 698.0 358.7 119.1 573.9 162.7 353.6 511.8 455.9 492.3 422.7 388.4 959.5 392.9 503.3 421.7 55.9 414.5 485.1 468.3 527.4 1339.1 198.6 209.2 233.0 251.4 207.7 246.0 234.6 237.8 226.0 205.4 226.7 209.6 79.2 169.9 167.8 0.0 49.9 0.0 0.0 0.0 0.0 0.0 205.7 169.8 0.0 0.0 100.3 171.0 0.0 784.3 86.3 0.0 1173.9 358.3 0.0 125.3 163.3 73.0 0.0 0.0 0.0 269.7 463.0 97.8 0.0 119.3 89.6 198.7 0.0 0.0 409.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 179.9 0.0 0.0 0.0 0.0 199.1 0.0 0.0 24.0 0.0 0.0 939.6 95.5 0.0 0.0 0.0 87.1 0.0 0.0 0.0 0.0 578.2 54.6 319.2 0.0 0.0 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5F1C "ATP5C, ATP5C1, ATP5CL1" ENSG00000165629 "ATP synthase F1 subunit gamma" P36542 10 7788147-7807815 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 895.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 517.1;Distal tubular cells: 890.2;Ductal cells: 453.9;Extravillous trophoblasts: 428.5;Hofbauer cells: 423.4;Proximal tubular cells: 938.6;Theca cells: 413.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060949 Approved NA NA 70000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA060949: AB_2684395" "unprognostic (1.81e-2)" "unprognostic (8.34e-2)" "unprognostic (3.87e-2)" "unprognostic (1.69e-2)" "unprognostic (2.17e-2)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (8.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-3)" "unprognostic (1.62e-1)" "unprognostic (4.12e-1)" "prognostic favorable (9.26e-4)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-2)" "unprognostic (4.08e-2)" 123.7 265.0 82.8 103.2 82.4 149.0 164.8 111.3 111.0 122.5 102.6 240.9 254.7 100.9 150.1 145.9 114.7 112.6 710.9 81.5 94.3 399.9 368.6 93.5 133.0 85.4 83.2 86.8 182.2 411.4 76.7 147.5 86.4 117.5 274.7 161.6 168.3 136.2 537.8 110.7 205.7 146.1 88.8 96.4 174.3 71.1 89.1 192.5 161.7 895.1 175.3 163.8 91.0 90.9 301.2 266.8 255.2 219.3 212.5 276.7 241.2 211.1 176.1 365.7 351.6 511.4 293.8 323.8 163.3 248.0 95.3 337.9 318.3 342.8 325.5 222.3 381.6 351.7 169.3 479.8 172.2 193.6 249.6 222.9 234.1 224.7 134.5 315.7 426.7 321.8 283.4 230.1 352.6 419.0 451.9 217.7 173.3 623.4 201.8 301.9 179.1 460.6 637.5 301.0 141.3 168.2 186.0 417.5 417.1 287.3 437.9 315.9 202.7 151.7 205.3 349.2 229.8 159.2 194.7 265.5 224.7 286.2 127.3 373.0 273.8 241.9 158.5 363.1 185.3 199.2 180.7 174.5 370.4 158.6 146.4 159.6 88.5 226.9 428.2 237.8 261.4 349.3 82.8 82.4 111.3 111.0 81.5 94.3 85.4 83.2 86.4 88.8 89.1 90.9 196.2 118.6 95.4 0.0 30.4 0.0 0.0 0.0 0.0 0.0 156.2 239.3 0.0 0.0 60.7 215.2 0.0 517.1 85.3 0.0 890.2 453.9 0.0 160.9 125.4 76.7 0.0 0.0 0.0 381.8 428.5 89.5 0.0 170.4 97.1 163.2 0.0 0.0 423.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.6 0.0 0.0 140.6 0.0 0.0 0.0 0.0 304.4 0.0 0.0 12.0 0.0 0.0 938.6 64.8 0.0 0.0 0.0 102.0 0.0 0.0 0.0 0.0 371.9 49.1 413.9 0.0 0.0 ATP5MC3 ATP5G3 ENSG00000154518 "ATP synthase membrane subunit c locus 3" P48201 2 175176258-175181710 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1214.0;tongue: 1088.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 880.5;Distal tubular cells: 2666.7;Extravillous trophoblasts: 1022.6;Hofbauer cells: 1008.2;Proximal tubular cells: 2131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.45e-3)" "unprognostic (1.67e-1)" "prognostic favorable (9.90e-4)" "unprognostic (1.67e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.46e-2)" "unprognostic (6.03e-3)" "unprognostic (1.42e-2)" "unprognostic (7.90e-2)" "unprognostic (4.71e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.31e-6)" "unprognostic (2.86e-1)" "unprognostic (3.93e-1)" "unprognostic (4.55e-2)" "unprognostic (2.31e-2)" 195.7 199.2 134.9 131.1 142.0 141.2 164.5 160.3 155.0 126.4 168.1 343.9 378.7 127.8 126.5 305.3 107.3 75.8 1214.0 143.0 164.7 432.4 385.3 118.1 127.3 153.7 143.6 99.7 120.2 550.6 139.5 102.4 157.3 110.0 315.0 126.5 184.8 114.5 777.9 169.7 297.3 122.2 147.4 131.4 272.4 62.3 154.2 188.9 135.1 1088.5 176.3 171.8 165.4 150.0 268.4 232.3 346.7 381.8 290.0 255.9 387.1 242.7 255.1 334.8 290.9 700.0 216.4 661.1 276.5 272.0 365.7 343.3 440.2 419.9 348.5 278.3 411.7 538.7 312.1 896.6 225.9 702.4 308.8 279.9 317.7 377.5 239.3 257.4 341.9 313.2 587.0 305.1 370.3 361.9 541.1 587.3 460.6 638.4 726.1 417.1 321.5 648.4 664.5 590.9 310.5 196.3 195.1 521.4 557.0 487.5 313.4 567.0 231.6 55.9 263.2 1.7 338.0 239.5 327.1 582.4 319.8 420.8 251.8 115.2 293.9 126.9 168.4 332.1 170.7 202.4 176.5 184.2 425.2 163.2 164.2 181.1 32.6 197.9 309.4 314.5 204.0 438.5 134.9 142.0 160.3 155.0 143.0 164.7 153.7 143.6 157.3 147.4 154.2 150.0 250.4 176.3 157.2 0.0 69.0 0.0 0.0 0.0 0.0 0.0 324.8 399.4 0.0 0.0 125.7 310.8 0.0 880.5 134.2 0.0 2666.7 479.0 0.0 271.2 264.1 79.3 0.0 0.0 0.0 375.2 1022.6 154.1 0.0 301.5 88.3 236.8 0.0 0.0 1008.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 205.5 0.0 0.0 205.7 0.0 0.0 0.0 0.0 391.9 0.0 0.0 26.5 0.0 0.0 2131.8 129.7 0.0 0.0 0.0 181.9 0.0 0.0 0.0 0.0 690.9 81.0 469.5 0.0 0.0 ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.8;tongue: 131.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 346.5;Distal tubular cells: 461.8;Extravillous trophoblasts: 405.2;Hofbauer cells: 373.0;Proximal tubular cells: 434.6;Syncytiotrophoblasts: 347.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" 19.3 15.7 10.3 11.5 12.5 15.3 18.8 14.5 27.4 17.4 3.9 51.6 28.8 16.6 16.0 26.8 23.9 16.3 109.0 12.1 10.2 40.3 40.2 13.7 24.0 13.4 12.0 19.2 18.5 33.8 7.1 21.6 14.9 22.3 33.6 28.5 29.8 18.7 135.8 15.7 19.0 17.9 9.6 15.2 22.6 15.5 12.8 15.7 31.1 131.0 22.4 21.9 7.4 14.1 55.6 17.6 44.1 36.9 35.6 34.2 34.1 57.0 68.9 67.3 54.7 31.8 29.1 84.9 52.3 45.5 14.3 56.1 69.4 79.5 65.1 61.9 33.2 76.1 21.3 21.5 26.0 98.3 70.8 30.3 40.9 69.3 66.9 17.7 60.0 11.9 78.7 33.6 46.3 35.4 153.3 30.0 34.9 19.2 90.5 41.2 143.6 34.0 54.7 26.0 37.2 13.4 49.4 72.7 55.6 12.6 54.8 46.0 50.6 32.0 49.1 59.4 61.2 41.8 44.5 172.1 70.8 77.6 60.8 3.5 15.4 7.1 14.8 10.0 12.2 12.9 15.1 13.3 16.1 15.2 16.9 10.4 4.8 9.8 9.0 9.2 15.1 44.2 10.3 12.5 14.5 27.4 12.1 10.2 13.4 12.0 14.9 9.6 12.8 14.1 73.2 67.3 83.8 0.0 31.5 0.0 0.0 0.0 0.0 0.0 112.9 155.3 0.0 0.0 57.6 125.0 0.0 346.5 56.4 0.0 461.8 237.3 0.0 132.5 111.0 58.8 0.0 0.0 0.0 196.7 405.2 57.0 0.0 125.4 89.6 82.1 0.0 0.0 373.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.8 0.0 0.0 98.8 0.0 0.0 0.0 0.0 162.6 0.0 0.0 9.8 0.0 0.0 434.6 74.3 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 347.7 41.8 208.0 0.0 0.0 ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 104.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" 8.6 18.5 7.4 8.6 7.6 15.9 8.7 8.3 11.1 8.4 8.3 11.1 8.7 6.8 8.7 14.4 8.1 4.9 23.9 7.5 9.1 16.1 19.7 7.8 10.5 7.9 8.1 7.3 9.8 26.3 9.3 7.7 8.4 9.1 10.4 6.4 10.7 6.6 24.7 14.6 10.2 8.4 7.8 10.4 12.0 10.9 7.8 10.8 10.6 27.8 14.5 9.1 9.5 8.4 13.0 24.1 15.4 14.7 15.1 16.2 15.6 11.2 16.4 23.7 20.1 31.8 19.3 26.0 24.6 19.5 13.1 19.9 14.8 24.1 20.7 20.9 11.7 5.8 14.8 18.6 25.5 8.2 17.3 19.5 16.8 21.4 11.9 16.7 27.4 21.3 9.3 8.9 13.1 26.8 19.4 12.8 10.4 48.3 13.3 19.8 27.1 29.9 19.0 11.4 9.9 13.5 14.9 7.6 14.0 104.2 24.4 16.2 11.6 6.0 12.4 22.2 10.9 6.2 8.4 9.6 10.7 11.9 31.4 7.8 41.5 14.7 9.3 28.6 10.4 27.9 6.9 8.9 49.2 19.7 10.7 8.0 3.0 8.9 22.3 41.6 12.9 20.7 7.4 7.6 8.3 11.1 7.5 9.1 7.9 8.1 8.4 7.8 7.8 8.4 8.8 6.4 7.8 9.4 20.3 15.3 12.0 23.7 9.6 10.5 13.9 10.8 28.2 20.0 14.4 12.9 33.3 32.5 20.7 10.9 66.5 19.3 52.9 10.5 6.0 10.0 14.5 13.7 13.7 12.3 30.9 9.1 8.2 8.5 13.3 25.7 9.3 20.8 45.5 10.1 14.1 18.2 16.2 22.3 22.5 42.6 6.5 18.2 17.8 7.5 28.1 13.8 13.4 9.0 9.6 16.0 24.4 6.8 18.6 13.8 25.8 58.8 17.2 17.7 0.0 8.4 10.4 28.2 20.9 17.6 18.9 28.7 9.0 15.9 20.5 12.3 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 BDP1 "HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR" ENSG00000145734 "B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB" A6H8Y1 5 71455651-71567820 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064166, HPA077984" Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA064166: , HPA077984: " "unprognostic (4.96e-2)" "unprognostic (2.19e-1)" "unprognostic (6.65e-2)" "unprognostic (3.01e-1)" "unprognostic (3.47e-2)" "unprognostic (1.44e-2)" "unprognostic (7.72e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (8.20e-2)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.86e-2)" "unprognostic (1.52e-1)" "unprognostic (7.83e-2)" "unprognostic (2.50e-2)" "unprognostic (5.86e-2)" 2.5 2.7 0.5 1.3 0.6 0.9 3.4 0.8 1.7 1.8 0.2 0.9 0.0 1.2 0.0 0.8 1.2 2.0 0.7 0.5 0.5 2.7 1.6 1.4 1.2 0.5 0.5 1.8 4.0 0.3 0.3 1.4 0.5 1.5 2.3 5.8 0.8 1.9 2.2 1.9 0.8 2.0 0.5 0.7 1.0 0.9 0.4 2.3 2.8 3.5 1.6 0.9 0.6 0.9 1.3 2.1 10.1 3.1 1.6 5.0 7.7 0.2 0.1 2.4 0.0 0.7 1.0 0.5 9.4 4.0 11.0 0.0 3.2 0.2 11.0 0.0 0.0 1.6 7.0 3.1 4.2 4.4 0.4 0.0 0.1 0.9 5.9 5.4 7.9 0.0 12.7 0.7 5.0 3.9 0.0 1.2 0.0 1.0 7.7 10.5 1.3 7.9 4.4 6.6 1.2 7.3 0.2 2.1 6.4 7.2 0.0 0.0 16.1 5.6 0.9 3.6 0.5 3.4 8.5 0.1 0.0 3.8 8.6 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.6 0.8 1.7 0.5 0.5 0.5 0.5 0.5 0.5 0.4 0.9 69.5 60.9 96.2 52.5 79.7 44.5 63.7 26.9 55.8 78.2 57.9 55.8 110.7 38.6 57.3 35.0 102.2 37.9 101.1 38.7 1.9 48.1 37.8 88.7 109.5 71.7 58.6 59.7 116.7 36.3 50.2 57.0 57.1 127.3 58.2 66.0 28.9 32.0 31.7 94.2 96.4 39.3 24.4 27.7 36.9 21.1 58.7 53.3 28.4 57.1 62.3 41.7 76.2 57.3 86.8 52.2 26.0 54.5 72.3 57.9 18.5 10.9 39.9 125.1 52.6 104.3 74.0 85.8 60.4 60.0 43.3 48.2 86.3 69.0 50.0 64.5 BECN1 "ATG6, VPS30" ENSG00000126581 "Beclin 1" Q14457 17 42810134-42833350 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Autophagy, Cell cycle, Cell division, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003949, CAB010143, HPA028949" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Nuclear bodies" "CAB010143: AB_626746, HPA003949: , HPA028949: AB_2672839" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (9.97e-2)" "unprognostic (3.80e-3)" "unprognostic (1.46e-1)" "unprognostic (2.01e-2)" "unprognostic (5.16e-3)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.59e-2)" "unprognostic (4.33e-2)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (1.02e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-2)" 45.3 41.4 26.9 41.8 27.7 50.7 43.9 27.4 37.8 35.7 30.9 70.3 56.6 31.5 47.7 49.5 36.1 34.4 58.9 28.5 29.1 47.9 43.7 39.6 47.9 27.4 27.9 26.7 39.5 41.7 20.5 26.2 27.8 42.3 64.8 26.5 36.0 41.3 95.8 36.4 50.1 44.4 28.4 39.8 53.0 24.2 28.3 41.4 36.7 77.6 56.2 49.2 29.7 28.5 47.4 79.0 27.9 48.7 95.7 56.8 54.9 95.1 104.2 69.5 73.8 61.4 61.9 68.9 69.3 118.9 70.0 52.7 48.9 85.3 123.4 105.0 59.4 58.0 74.9 105.5 71.4 111.0 114.3 76.8 99.1 69.4 66.0 61.8 90.2 75.4 50.5 67.1 86.4 40.1 66.1 61.1 29.0 88.5 40.6 56.3 100.6 69.3 74.1 88.6 33.5 34.9 52.0 43.5 100.7 61.4 72.0 92.9 121.6 82.8 38.8 57.0 99.7 103.8 84.8 57.4 84.3 54.0 106.7 154.1 133.2 122.1 103.1 152.1 105.1 112.6 114.4 111.6 120.2 123.7 96.4 100.2 191.0 107.8 144.2 75.7 180.1 171.8 26.9 27.7 27.4 37.8 28.5 29.1 27.4 27.9 27.8 28.4 28.3 28.5 43.7 38.5 46.1 11.8 38.7 29.7 26.7 40.1 39.3 12.3 38.3 22.7 6.0 30.0 39.1 12.9 10.4 23.5 37.8 59.5 58.7 46.2 18.2 35.0 28.3 33.9 28.3 36.2 12.1 69.6 32.3 23.1 42.3 31.5 43.1 20.5 31.4 46.2 38.8 21.9 11.7 60.2 30.5 65.4 36.8 11.9 21.5 43.1 42.7 3.7 67.2 26.9 50.4 5.5 9.8 53.6 45.4 26.7 51.2 37.8 49.1 40.3 51.7 13.4 26.3 25.6 36.0 31.6 14.9 44.9 37.6 38.0 39.8 33.8 51.1 46.7 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BRCC3 "BRCC36, C6.1A, CXorf53" ENSG00000185515 "BRCA1/BRCA2-containing complex subunit 3" P46736 X 155071420-155123077 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Metalloprotease, Protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048737 Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA048737: AB_2680504" "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "unprognostic (5.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (2.88e-2)" "unprognostic (4.48e-2)" "unprognostic (6.47e-3)" "unprognostic (1.33e-1)" "unprognostic (9.68e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (3.71e-3)" "unprognostic (7.14e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" 9.9 12.9 6.8 12.1 6.6 15.6 15.8 9.2 7.7 12.8 6.8 22.3 19.3 9.2 18.5 18.4 11.6 8.4 11.2 6.6 7.0 17.8 13.8 9.8 15.4 5.9 7.1 8.1 11.4 14.7 5.2 14.0 6.7 14.6 23.3 12.9 18.5 10.9 17.8 11.1 16.9 10.6 5.4 11.0 15.6 2.3 7.4 13.4 15.2 17.6 15.5 12.6 6.3 6.6 95.6 45.1 24.4 19.6 20.9 17.7 37.9 35.9 25.8 24.1 52.3 44.0 40.1 84.1 62.8 22.1 36.1 36.3 54.4 33.6 38.0 45.4 42.1 17.7 76.1 41.4 15.8 62.8 25.5 17.3 16.9 35.1 28.5 23.1 30.1 32.2 27.4 24.9 24.6 33.6 25.8 28.8 22.3 101.9 41.9 36.2 43.3 42.0 36.8 36.5 38.0 17.3 25.6 43.6 27.3 31.5 25.2 33.7 31.5 20.4 32.1 27.6 53.8 30.0 56.1 114.5 28.2 61.5 25.3 36.8 18.8 34.0 20.0 22.9 23.4 17.6 19.3 18.2 21.2 16.7 14.8 16.6 10.5 28.4 24.1 13.3 25.4 16.9 6.8 6.6 9.2 7.7 6.6 7.0 5.9 7.1 6.7 5.4 7.4 6.6 12.0 32.1 23.3 16.6 14.0 5.5 7.0 13.8 6.8 13.0 15.0 14.0 27.2 10.0 28.5 7.3 14.6 26.7 17.6 25.5 19.6 22.9 0.6 13.8 13.7 10.6 9.6 17.1 31.9 19.8 26.6 11.3 12.8 15.9 26.6 13.7 8.6 8.6 17.4 8.4 35.2 22.6 16.2 9.5 7.0 1.3 5.9 14.5 5.4 15.9 22.3 12.9 20.6 26.7 29.2 14.7 16.8 12.0 21.1 10.3 16.3 18.0 25.1 14.5 19.7 12.6 22.9 1.2 1.3 26.2 6.5 13.5 14.9 18.3 27.3 8.3 C11orf58 SMAP ENSG00000110696 "Chromosome 11 open reading frame 58" O00193 11 16613132-16758340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036591, HPA076406" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" Nucleoplasm "HPA036591: AB_10669909, HPA076406: AB_2686798" "unprognostic (8.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.20e-1)" "unprognostic (4.31e-2)" "unprognostic (2.88e-1)" "unprognostic (9.19e-2)" "prognostic unfavorable (5.84e-5)" "unprognostic (1.30e-1)" "unprognostic (7.84e-2)" "unprognostic (9.45e-3)" "unprognostic (1.76e-1)" "unprognostic (2.06e-1)" "unprognostic (4.41e-2)" "unprognostic (7.30e-2)" "unprognostic (9.77e-2)" "unprognostic (1.39e-1)" "unprognostic (1.50e-1)" 142.2 135.1 52.2 129.5 57.8 128.3 94.5 55.3 79.7 91.5 66.5 101.8 89.9 136.1 73.8 172.3 128.0 115.6 159.9 52.0 62.7 114.9 132.9 102.9 162.9 57.6 56.0 172.0 127.8 115.1 78.7 123.9 61.3 111.7 71.7 94.2 128.6 85.3 212.2 99.8 96.5 113.8 56.8 125.8 111.7 89.6 55.4 138.2 162.1 109.6 127.9 125.1 81.3 69.1 416.1 362.9 390.3 197.0 199.5 162.3 272.8 419.2 213.0 276.2 245.5 348.0 397.7 383.1 315.2 253.7 311.4 242.3 275.0 206.9 232.8 485.8 289.9 342.7 286.8 310.1 243.4 492.8 276.2 182.3 230.6 168.9 336.6 209.7 178.4 232.6 435.2 246.5 191.1 247.8 506.5 211.7 291.1 212.7 197.6 404.3 413.6 196.0 158.6 248.7 269.8 267.4 372.4 273.4 501.4 225.0 244.4 315.7 359.5 336.7 268.2 407.1 388.0 164.0 648.6 525.2 297.2 275.3 326.1 587.6 390.4 552.8 407.8 451.9 482.3 621.9 451.4 435.0 429.7 578.9 506.9 440.6 186.9 433.9 490.1 544.7 522.0 896.2 52.2 57.8 55.3 79.7 52.0 62.7 57.6 56.0 61.3 56.8 55.4 69.1 188.3 246.8 222.5 41.8 219.8 257.1 275.3 379.8 167.9 169.5 170.9 168.4 206.4 178.7 259.1 200.5 150.1 312.2 242.8 65.6 428.4 249.7 65.6 204.2 202.0 217.3 159.2 213.7 72.5 228.1 346.8 258.2 73.4 139.8 237.3 151.3 175.6 163.8 227.0 143.0 68.6 133.2 299.1 164.3 261.0 34.3 205.9 180.1 229.5 45.0 249.9 230.5 248.2 61.3 63.5 232.3 104.3 204.2 183.0 324.1 103.4 364.6 237.0 215.7 157.8 164.9 246.8 331.6 245.7 142.5 276.6 453.5 217.3 188.2 118.7 296.6 C1orf109 FLJ20508 ENSG00000116922 "Chromosome 1 open reading frame 109" Q9NX04 1 37681570-37692249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.2;Suprabasal keratinocytes: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027110, HPA027127" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Nucleoli" "HPA027110: AB_10611813, HPA027127: AB_1845628" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (2.43e-1)" "unprognostic (3.30e-3)" "unprognostic (1.71e-2)" "unprognostic (7.13e-3)" "prognostic unfavorable (1.76e-7)" "unprognostic (1.93e-1)" "unprognostic (1.48e-2)" "unprognostic (8.38e-2)" "unprognostic (1.73e-1)" "unprognostic (3.79e-3)" "unprognostic (9.96e-2)" "unprognostic (1.66e-2)" "unprognostic (2.25e-1)" "unprognostic (7.96e-3)" "unprognostic (1.69e-1)" 8.8 10.7 7.7 7.3 6.8 8.0 9.7 7.1 7.5 8.9 5.9 7.2 8.2 10.2 10.0 10.1 9.8 6.9 8.3 7.0 7.5 9.2 7.8 5.5 11.9 7.0 8.1 13.4 14.6 15.0 6.1 10.4 7.6 10.6 5.6 5.3 12.3 10.1 9.7 10.5 5.7 8.2 7.9 7.7 6.9 8.3 10.3 9.1 11.4 10.0 9.7 8.1 7.9 8.2 17.7 20.1 16.9 27.8 14.5 10.4 38.5 20.9 14.7 30.7 22.6 30.8 20.8 25.0 24.4 9.2 14.2 25.3 31.5 21.2 31.3 40.3 35.1 28.3 20.7 19.5 27.9 31.6 18.0 14.2 25.7 30.4 39.8 13.4 15.7 21.6 57.2 29.5 17.7 12.1 30.9 13.9 52.9 18.1 38.0 30.2 35.4 69.0 16.4 14.9 50.8 24.4 18.4 27.9 43.1 16.9 15.7 13.9 10.6 30.7 19.3 25.0 40.8 24.0 29.0 52.0 15.4 30.4 33.0 3.5 9.7 6.9 18.9 7.9 29.9 21.2 22.8 18.3 11.6 18.7 28.8 25.0 1.9 24.8 8.8 54.1 12.5 15.0 7.7 6.8 7.1 7.5 7.0 7.5 7.0 8.1 7.6 7.9 10.3 8.2 10.9 6.4 7.9 4.2 12.9 50.2 24.1 5.9 22.8 10.1 15.6 15.1 5.5 5.7 10.8 3.7 10.4 14.9 12.2 6.7 13.7 10.5 1.5 5.8 12.8 11.5 4.2 45.3 9.5 7.3 14.0 14.4 6.1 6.2 11.4 9.6 6.4 6.6 5.4 16.8 7.2 5.1 8.2 4.4 9.0 1.0 9.9 4.8 12.4 4.7 7.3 10.4 17.5 5.0 5.0 10.2 8.1 13.9 10.9 21.3 5.5 8.9 5.6 14.6 0.0 17.5 8.5 25.7 25.5 15.5 62.1 7.9 12.0 11.9 8.3 13.2 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 CALCOCO2 "MGC17318, NDP52" ENSG00000136436 "Calcium binding and coiled-coil domain 2" Q13137 17 48831018-48866522 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 1127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022989, HPA023019, HPA023195" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Vesicles "HPA022989: AB_1845914, HPA023019: AB_1845915, HPA023195: AB_1845916" "unprognostic (3.71e-1)" "unprognostic (2.87e-1)" "unprognostic (3.84e-2)" "unprognostic (3.37e-2)" "unprognostic (4.90e-2)" "unprognostic (4.46e-2)" "unprognostic (2.05e-1)" "unprognostic (2.28e-1)" "unprognostic (3.88e-1)" "unprognostic (2.15e-1)" "unprognostic (2.41e-1)" "unprognostic (4.03e-2)" "unprognostic (3.52e-2)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (7.57e-2)" "unprognostic (5.65e-2)" 117.9 59.2 36.5 55.3 43.8 62.9 95.3 41.6 50.8 81.0 72.3 101.0 68.1 69.2 61.0 88.6 82.2 66.2 139.1 35.3 45.3 75.7 120.3 91.4 53.2 48.7 42.0 86.6 56.6 76.8 46.6 63.3 49.2 55.6 101.5 76.4 52.5 72.5 158.4 68.2 75.4 87.8 39.0 68.8 71.6 136.3 41.0 74.4 75.3 170.3 67.1 80.9 76.9 52.0 126.0 79.4 33.1 64.0 241.2 173.7 95.0 120.2 160.0 135.9 151.3 150.8 80.6 42.5 117.0 146.5 115.9 68.2 81.4 101.7 162.6 193.3 66.9 40.7 48.0 59.1 276.8 137.4 196.8 258.1 148.1 144.3 103.9 129.0 101.3 130.7 74.9 124.3 119.2 36.8 119.5 73.6 10.3 278.9 97.7 77.8 161.7 81.0 52.2 39.2 13.1 27.9 37.6 24.3 106.0 66.6 154.2 76.5 97.7 147.1 44.9 91.0 85.8 110.4 165.1 30.0 89.2 69.0 61.4 108.9 115.1 115.5 56.6 121.5 54.2 54.1 49.9 58.9 67.1 46.7 50.5 55.8 132.8 105.0 132.3 33.6 107.2 89.7 36.5 43.8 41.6 50.8 35.3 45.3 48.7 42.0 49.2 39.0 41.0 52.0 166.2 115.4 98.1 20.5 42.1 36.6 73.3 40.9 40.9 16.8 34.7 32.4 169.1 37.1 48.4 33.1 50.1 50.2 48.6 124.5 37.2 47.2 1127.4 37.4 89.7 104.6 50.4 40.8 31.0 42.2 45.3 79.1 31.6 44.0 100.0 29.8 110.3 58.9 27.6 8.4 21.2 44.7 24.4 119.2 54.3 233.3 70.2 70.7 26.6 28.1 57.4 45.9 64.9 26.7 27.3 37.7 54.6 74.1 56.2 57.6 81.5 48.9 28.4 72.7 72.3 69.6 76.2 152.5 32.7 55.6 46.9 81.3 54.6 96.3 66.1 66.1 CAPZA2 "CAPPA2, CAPZ" ENSG00000198898 "Capping actin protein of muscle Z-line subunit alpha 2" P47755 7 116811070-116922049 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007470, HPA007643" Uncertain Approved Cytosol No No 4500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA007470: AB_1845985, HPA007643: AB_2667886" "unprognostic (1.37e-2)" "unprognostic (2.25e-3)" "unprognostic (4.16e-2)" "unprognostic (3.16e-1)" "unprognostic (1.53e-1)" "unprognostic (2.63e-3)" "prognostic unfavorable (9.34e-5)" "unprognostic (1.90e-2)" "unprognostic (1.80e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-3)" "unprognostic (2.52e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (2.91e-3)" "unprognostic (6.58e-2)" 26.3 20.1 17.0 20.0 17.3 43.3 21.8 22.5 25.8 18.0 16.9 24.4 20.4 19.7 19.0 20.8 14.2 20.7 45.7 21.3 17.5 37.3 33.9 23.8 20.1 17.0 17.1 12.6 13.4 19.4 7.5 24.9 20.5 20.3 23.9 13.4 14.6 20.5 64.3 12.3 23.4 28.1 14.5 22.3 20.0 8.7 19.6 16.4 22.8 53.1 17.3 28.1 11.3 18.3 30.0 19.5 19.8 25.2 35.9 37.8 9.8 28.7 41.3 28.8 32.7 14.5 38.1 20.8 46.5 41.3 36.1 18.2 20.4 24.1 45.4 22.7 14.9 31.3 18.0 24.6 22.2 21.2 40.9 30.2 26.9 22.9 21.9 34.8 63.2 12.9 20.8 35.2 57.9 13.0 28.3 35.6 29.5 31.3 16.8 19.7 26.2 42.1 69.3 24.6 20.6 23.5 27.7 104.1 29.7 25.0 14.5 25.0 23.0 47.0 14.6 37.5 28.5 27.7 21.0 39.6 28.0 29.6 34.0 57.3 34.8 45.6 11.1 45.6 13.2 14.4 13.5 11.9 33.2 12.6 12.9 13.1 69.4 15.9 54.9 18.1 18.1 45.3 17.0 17.3 22.5 25.8 21.3 17.5 17.0 17.1 20.5 14.5 19.6 18.3 177.9 73.7 67.4 44.4 109.4 243.1 219.8 224.3 94.4 106.6 85.1 67.3 219.4 71.4 146.5 171.0 27.1 151.7 96.2 147.4 516.5 193.1 9.6 139.4 113.7 189.5 121.2 263.9 59.2 160.3 204.0 124.8 103.5 340.1 126.2 48.8 262.3 110.6 314.1 107.7 48.0 102.6 286.8 238.5 274.9 16.2 74.6 262.9 181.5 64.6 222.4 164.5 72.1 49.8 47.1 193.1 147.5 110.9 83.0 140.9 182.6 519.7 99.7 95.9 92.1 122.8 188.9 43.1 47.0 94.1 218.8 144.1 108.6 78.7 109.9 207.0 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: AB_2072067" "unprognostic (1.43e-1)" "unprognostic (5.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (6.62e-3)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.69e-2)" "prognostic favorable (1.11e-7)" "unprognostic (3.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 14.0 20.9 10.1 11.8 11.4 4.9 17.4 10.5 17.1 10.1 7.3 14.3 35.5 10.4 14.3 14.2 12.9 11.9 12.2 9.9 11.3 22.5 32.3 8.8 14.0 11.1 10.5 10.8 16.3 18.3 7.5 10.6 11.5 11.6 15.7 11.1 13.5 12.0 28.4 10.3 30.8 10.3 11.3 10.5 20.0 10.9 11.9 11.4 18.8 15.2 14.2 11.7 9.4 13.0 50.1 27.9 25.8 24.7 22.8 33.0 17.2 41.0 39.5 24.7 24.0 11.2 17.9 53.6 27.7 20.9 21.2 23.1 23.6 40.0 35.5 20.3 16.4 66.9 23.1 19.3 36.9 23.8 20.8 37.1 25.9 27.1 37.6 28.7 54.0 33.7 32.2 24.6 27.8 19.2 55.3 19.9 37.9 49.4 14.8 18.7 44.4 28.8 32.3 26.7 15.1 41.7 27.5 21.0 42.8 19.0 24.0 13.1 44.6 22.5 33.4 38.9 21.7 24.5 33.8 19.5 35.0 30.8 23.8 20.3 8.9 6.6 15.2 12.6 17.8 19.8 19.6 16.1 11.6 15.5 18.3 19.3 3.2 14.3 13.4 18.1 23.2 10.4 10.1 11.4 10.5 17.1 9.9 11.3 11.1 10.5 11.5 11.3 11.9 13.0 47.5 25.6 38.9 12.4 34.8 21.4 39.6 46.5 55.2 42.6 57.3 61.6 62.5 60.1 44.5 53.3 12.5 77.6 31.2 61.6 109.5 76.9 183.1 46.8 51.0 54.2 26.5 46.7 30.5 134.6 56.0 49.3 63.2 33.3 63.9 39.3 55.0 144.5 44.7 55.5 21.9 58.6 46.8 33.5 27.2 162.9 47.2 27.4 37.4 12.2 44.4 60.2 35.0 12.1 17.7 83.7 51.1 47.4 40.7 55.2 182.1 128.6 53.7 38.9 46.0 44.4 49.1 91.1 59.6 56.7 22.3 42.4 38.7 88.1 71.2 36.0 CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029674: AB_10602703, HPA072573: AB_2686535, HPA075958: " "unprognostic (6.33e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.38e-1)" "unprognostic (3.54e-1)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (1.88e-1)" "unprognostic (6.43e-2)" "unprognostic (7.46e-2)" "unprognostic (1.16e-1)" 57.9 67.3 24.3 42.5 33.6 29.0 57.1 28.8 39.2 47.7 46.9 83.4 87.1 39.1 53.7 52.6 43.9 48.2 65.5 29.3 27.9 72.0 102.2 52.7 33.5 28.8 27.4 35.3 59.8 84.6 21.9 54.8 29.9 60.2 80.6 46.9 62.4 52.0 115.3 52.2 78.2 42.1 30.1 35.6 78.5 32.1 26.0 29.9 62.0 83.7 40.5 58.5 29.3 34.3 143.3 133.8 81.4 71.9 112.4 74.0 158.0 141.9 92.6 96.1 112.4 118.7 127.0 112.9 74.3 100.9 110.8 114.3 99.3 88.1 168.9 39.4 101.2 160.9 106.4 117.3 107.6 129.9 81.3 78.5 121.3 132.4 113.2 67.9 81.3 55.3 183.5 95.5 79.4 116.1 100.5 48.1 70.8 179.4 134.0 92.2 157.9 154.6 115.3 161.1 74.2 101.5 95.2 242.8 120.3 103.0 159.8 70.4 104.0 177.6 112.9 130.6 166.0 93.9 119.9 112.8 103.9 81.4 147.3 53.2 59.7 75.6 40.7 61.5 47.9 38.4 39.8 37.9 82.5 31.7 41.1 36.2 47.6 43.4 65.9 54.7 49.0 52.0 24.3 33.6 28.8 39.2 29.3 27.9 28.8 27.4 29.9 30.1 26.0 34.3 96.9 144.2 122.2 16.3 46.6 100.8 108.5 95.9 98.4 40.9 65.9 53.6 129.0 72.9 128.3 60.7 14.6 111.1 59.0 99.8 9.8 115.3 17.9 80.3 73.9 83.9 52.2 76.6 26.2 105.1 98.3 85.3 65.7 126.0 45.5 31.2 68.2 96.3 57.5 57.2 25.9 95.1 83.4 56.9 58.3 11.5 47.8 60.7 39.2 13.1 52.9 55.3 25.7 22.6 25.5 92.0 62.6 56.1 56.0 89.6 87.5 32.6 83.0 27.9 72.3 117.2 92.1 82.0 44.7 90.1 90.8 144.1 42.7 53.0 110.5 83.3 CCDC58 FLJ33273 ENSG00000160124 "Coiled-coil domain containing 58" Q4VC31 3 122359591-122383231 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051965 Approved Approved Nucleoli,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoli "HPA051965: AB_2681676" "unprognostic (1.51e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.64e-2)" "unprognostic (6.98e-3)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.72e-2)" "unprognostic (1.03e-2)" "unprognostic (4.98e-3)" "unprognostic (5.26e-3)" "unprognostic (1.84e-2)" "unprognostic (7.11e-3)" "unprognostic (1.03e-3)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "prognostic favorable (7.29e-4)" 14.7 21.0 16.9 15.7 17.8 18.0 19.0 18.2 28.2 10.7 18.4 28.5 22.5 11.7 24.6 23.2 10.6 13.4 27.3 17.1 17.6 46.8 49.8 9.0 23.3 17.8 18.1 13.1 13.8 14.9 7.8 14.4 18.2 11.1 29.1 17.1 11.3 10.6 78.8 15.0 18.6 11.4 17.4 12.1 16.4 9.4 18.1 16.2 18.3 47.2 21.5 22.6 12.5 18.3 135.1 41.9 78.2 50.2 28.5 39.8 100.6 50.5 54.3 119.4 116.4 118.4 66.4 98.0 84.6 38.6 92.7 91.9 127.9 86.3 142.5 34.1 45.3 115.9 28.5 145.6 47.5 174.5 39.5 33.0 43.9 73.5 79.8 50.7 55.9 85.8 133.6 41.6 63.7 67.2 111.7 123.6 150.0 147.2 78.1 72.8 92.9 120.1 83.7 70.3 78.8 38.4 58.5 61.5 150.5 65.3 61.2 112.8 32.6 66.4 86.1 28.6 102.3 32.9 47.5 217.4 75.7 83.3 60.0 0.9 7.7 2.7 15.2 16.7 18.0 20.9 19.9 20.1 16.5 19.2 23.0 22.2 1.4 19.2 14.2 29.2 17.2 6.7 16.9 17.8 18.2 28.2 17.1 17.6 17.8 18.1 18.2 17.4 18.1 18.3 5.7 3.2 17.0 8.1 18.1 15.3 19.1 21.4 21.1 10.5 14.1 10.4 32.0 20.0 22.2 12.9 10.4 21.8 8.4 19.6 54.8 31.4 0.5 24.7 20.5 13.7 5.4 14.1 11.3 30.0 44.7 12.8 16.8 26.2 21.5 14.4 10.8 50.5 17.8 0.0 13.2 27.7 16.2 8.7 7.6 1.5 12.8 8.9 8.8 2.8 19.8 9.7 16.5 11.6 11.8 31.9 14.7 8.2 12.5 30.7 23.9 114.0 22.5 9.6 13.1 15.1 41.8 23.1 31.0 30.8 18.5 15.2 10.9 11.8 35.1 23.0 CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.0;Collecting duct cells: 20.2;Ductal cells: 30.0;Pancreatic endocrine cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 4.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.3" "Cell line enhanced" "Detected in many" "HaCaT: 122.5;hTERT-RPE1: 110.8;WM-115: 138.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" 4.9 10.3 9.5 7.7 13.1 2.8 8.1 10.9 10.7 12.0 15.0 73.4 9.9 23.9 7.3 33.2 10.8 12.0 53.0 9.0 12.7 10.2 5.0 12.3 3.3 13.1 12.6 4.0 25.3 11.3 10.2 3.9 12.7 16.2 12.5 4.3 28.3 22.7 67.4 15.4 18.1 24.2 11.6 5.6 22.3 8.3 12.7 1.3 45.2 65.1 5.9 25.9 16.7 12.6 50.0 6.8 0.0 0.4 1.1 4.6 2.5 14.8 14.6 16.1 15.6 0.5 44.7 0.3 20.1 47.8 58.6 122.5 0.2 40.4 15.1 0.0 0.3 14.9 64.4 4.7 8.5 0.2 2.8 5.7 9.0 6.9 20.3 110.8 11.6 0.8 0.1 0.7 27.9 0.0 0.5 0.0 0.2 23.1 12.7 0.0 4.2 0.2 48.0 2.8 0.1 3.6 8.8 19.1 8.4 0.2 1.9 2.3 62.1 29.7 47.2 7.9 39.8 0.0 0.1 0.6 36.2 2.8 138.3 4.3 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 0.4 0.1 0.2 0.0 0.2 9.5 13.1 10.9 10.7 9.0 12.7 13.1 12.6 12.7 11.6 12.7 12.6 2.7 12.8 10.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.5 3.0 0.0 0.0 1.3 20.2 0.0 0.0 0.2 0.0 1.9 30.0 0.0 1.8 0.4 0.6 0.0 0.0 0.0 3.7 0.1 0.6 0.0 2.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 CCNG1 CCNG ENSG00000113328 "Cyclin G1" P51959 5 163437569-163446151 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 265.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB000350 Supported Supported Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB000350: " "unprognostic (2.49e-2)" "unprognostic (1.64e-1)" "prognostic favorable (7.00e-4)" "unprognostic (2.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.26e-1)" "unprognostic (6.25e-2)" "unprognostic (1.58e-1)" "unprognostic (6.15e-2)" "unprognostic (1.45e-2)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.38e-3)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" "unprognostic (7.89e-2)" 51.2 48.8 21.0 30.4 23.0 38.3 67.2 22.9 25.8 63.4 27.8 68.0 137.2 50.5 73.4 47.8 61.8 56.7 50.4 19.1 23.4 123.5 129.6 33.4 49.0 24.7 21.6 112.0 74.4 39.7 14.6 54.0 25.0 71.4 87.0 21.3 56.3 55.7 163.6 23.5 109.1 52.3 23.5 35.5 57.3 20.7 21.7 50.3 62.4 120.6 47.0 59.7 33.8 28.6 54.9 59.8 246.6 138.8 207.9 397.3 258.2 74.1 181.2 73.8 165.2 130.4 109.4 134.1 73.7 100.1 121.7 22.2 137.2 185.0 107.9 63.7 171.9 106.6 71.7 230.0 226.4 49.9 68.9 433.8 105.6 73.3 75.1 221.5 241.1 88.3 92.3 92.8 253.4 33.8 89.6 66.5 113.3 40.1 52.7 74.6 120.7 75.2 179.5 209.4 57.6 65.6 0.4 30.5 154.0 155.2 115.5 155.8 140.5 47.6 101.0 40.8 66.2 81.5 34.2 87.7 84.3 81.4 80.6 44.5 25.6 31.0 35.8 36.1 53.9 55.4 63.2 49.3 59.6 33.9 84.5 72.0 10.9 40.7 36.7 22.6 80.9 63.9 21.0 23.0 22.9 25.8 19.1 23.4 24.7 21.6 25.0 23.5 21.7 28.6 20.8 25.6 20.0 7.5 67.3 57.2 94.7 64.7 103.0 12.4 64.4 33.0 52.9 77.2 39.7 36.8 0.0 138.7 49.8 48.2 162.4 73.0 8.1 30.6 27.5 43.5 71.0 96.3 8.4 119.0 107.7 57.1 110.6 46.1 43.7 108.8 61.1 51.7 60.0 15.2 8.8 113.2 44.7 74.8 70.5 6.1 75.8 60.8 37.4 15.0 52.0 29.9 54.6 4.5 12.7 91.1 80.2 72.2 63.5 107.2 223.4 265.9 11.2 10.8 39.5 42.4 73.4 8.8 12.1 61.5 44.2 97.3 76.4 81.5 182.7 104.3 CDC26 "ANAPC12, APC12, C9orf17" ENSG00000176386 "Cell division cycle 26" Q8NHZ8 9 113255835-113275572 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044130 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA044130: AB_10963690" "unprognostic (9.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "unprognostic (2.60e-1)" "unprognostic (1.48e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (7.27e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (7.49e-3)" "unprognostic (8.84e-2)" "unprognostic (1.27e-1)" "unprognostic (6.26e-2)" "unprognostic (3.79e-2)" 42.9 33.1 27.1 34.1 27.4 28.9 39.0 27.3 39.5 34.0 33.8 37.7 30.9 28.2 41.7 34.2 31.0 25.3 52.9 26.3 29.3 49.2 53.1 34.2 42.5 28.1 27.2 33.8 29.9 58.8 29.6 27.7 29.5 36.9 34.2 41.7 32.5 31.8 47.5 36.2 37.2 26.5 29.1 42.0 34.3 22.4 27.7 46.0 35.2 52.4 46.9 40.3 32.7 29.2 47.0 73.3 62.5 32.2 104.4 89.3 29.0 67.1 100.7 67.6 66.3 78.0 53.9 84.1 56.6 58.3 77.2 88.8 53.2 99.1 66.8 80.3 38.9 55.7 71.4 73.1 50.8 99.6 55.0 62.2 68.9 62.5 92.2 70.3 91.7 67.2 85.3 63.7 51.8 94.7 86.2 62.9 102.7 213.1 65.1 73.1 134.3 42.9 71.1 78.2 48.1 45.7 88.4 63.7 51.4 68.2 57.9 43.4 62.1 40.5 37.9 61.4 87.5 43.5 79.5 67.4 57.1 58.3 41.0 239.6 116.9 274.2 177.6 127.3 220.0 233.4 222.3 195.9 122.2 201.0 253.5 195.2 182.8 192.8 122.9 103.8 241.6 171.5 27.1 27.4 27.3 39.5 26.3 29.3 28.1 27.2 29.5 29.1 27.7 29.2 91.9 35.3 40.9 3.3 58.5 77.9 79.3 111.8 68.3 20.3 58.2 79.8 5.3 45.8 61.2 22.0 22.9 45.7 59.6 51.1 113.5 64.4 22.2 53.4 67.4 65.7 31.8 55.2 5.0 59.5 68.6 54.3 21.4 43.3 27.3 48.6 63.1 83.3 58.4 15.2 5.5 50.7 73.2 51.6 92.0 13.9 80.2 49.6 51.6 2.8 67.9 76.7 72.1 5.0 6.7 58.0 62.7 43.6 51.7 91.4 88.9 169.2 68.1 36.4 26.3 54.2 43.7 35.3 16.8 55.0 90.8 47.9 75.4 50.0 47.2 97.7 CDC5L "CDC5, CEF1, hCDC5, PCDC5RP" ENSG00000096401 "Cell division cycle 5 like" Q99459 6 44387706-44450425 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 291.8;Late spermatids: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006302, HPA011361, CAB012275" Supported Supported Nucleoplasm NA NA 22000 "Cluster 42: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB012275: , HPA006302: AB_1078488, HPA011361: AB_1846379" "unprognostic (2.67e-1)" "unprognostic (9.31e-2)" "unprognostic (8.26e-3)" "unprognostic (4.17e-3)" "unprognostic (2.01e-2)" "unprognostic (2.17e-1)" "unprognostic (7.96e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.02e-5)" "unprognostic (1.01e-2)" "unprognostic (6.31e-2)" "unprognostic (1.63e-1)" "unprognostic (4.33e-2)" "unprognostic (3.08e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" 11.5 11.9 6.7 10.7 7.1 21.3 13.5 10.1 9.4 10.3 7.0 10.5 9.4 12.0 13.2 10.9 9.7 8.7 13.8 7.3 7.0 10.5 18.7 9.6 13.4 6.7 6.8 14.0 10.1 19.8 5.7 12.0 7.1 11.8 11.3 13.2 9.7 9.4 17.8 8.5 9.4 11.7 6.9 10.5 9.7 13.2 6.9 15.3 10.8 22.5 14.1 12.1 8.1 8.7 43.0 16.5 39.8 32.5 16.0 20.7 22.5 30.6 23.8 37.9 41.5 21.7 14.4 40.8 24.8 24.7 30.8 26.6 41.8 24.2 56.4 34.5 37.6 54.5 15.4 28.1 14.6 41.3 28.2 15.9 20.9 37.0 31.9 21.7 25.0 20.7 42.6 23.3 34.7 29.0 38.4 28.1 28.0 103.5 15.1 29.6 45.7 26.4 21.5 25.2 43.8 38.0 24.7 16.5 33.3 25.4 23.2 39.6 23.0 32.4 32.8 25.5 43.7 19.9 25.8 73.8 20.9 35.3 33.2 20.2 13.1 17.5 10.4 15.7 11.8 9.9 10.0 11.7 13.0 11.3 10.7 10.4 19.9 14.8 18.1 11.2 14.6 8.5 6.7 7.1 10.1 9.4 7.3 7.0 6.7 6.8 7.1 6.9 6.9 8.7 57.3 73.7 50.3 14.7 48.5 44.2 69.2 58.0 55.8 36.4 26.7 29.5 82.2 30.0 80.5 23.9 31.3 57.5 58.2 26.8 39.2 53.4 291.8 63.7 64.2 51.5 36.1 48.1 20.6 55.2 49.4 52.2 28.5 72.1 71.0 58.8 26.7 44.7 45.3 32.0 34.7 40.7 52.9 38.6 29.8 285.9 61.5 53.1 19.6 18.7 74.3 65.8 45.3 14.1 33.0 47.8 34.5 55.3 37.7 49.0 18.6 28.6 78.6 38.1 65.7 67.9 76.2 48.2 98.7 35.6 38.4 71.7 46.8 59.8 40.8 62.5 CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;Cardiomyocytes: 37.1;Cytotrophoblasts: 17.7;dendritic cells: 20.2;Extravillous trophoblasts: 16.8;Hofbauer cells: 36.8;Plasma cells: 12.4;Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 132.3;WM-115: 118.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 38.1 26.1 12.4 16.5 16.1 27.2 17.6 18.0 15.4 33.9 14.0 20.8 18.7 20.6 15.1 24.9 22.4 23.3 20.8 14.0 15.1 27.9 31.2 24.3 20.3 14.7 17.5 23.1 16.4 26.1 8.0 22.9 16.7 24.3 19.6 18.2 14.0 19.9 28.9 18.7 21.1 18.3 14.7 25.3 23.5 28.8 15.5 21.2 49.9 28.3 22.7 23.7 16.0 17.6 44.9 22.7 21.6 19.0 132.3 36.6 29.0 24.8 30.8 18.8 24.8 34.4 25.3 21.5 52.3 26.9 25.8 26.7 33.4 34.4 28.6 27.1 15.2 18.2 24.4 18.4 33.6 18.2 20.1 27.9 23.8 22.3 24.9 30.5 22.1 28.3 33.0 32.0 25.0 23.0 21.6 13.2 27.9 10.2 16.8 18.0 28.5 20.2 30.5 54.0 16.4 16.5 31.6 21.6 31.8 45.4 21.3 30.5 30.1 12.6 15.1 22.8 20.3 29.1 41.6 24.8 21.4 30.7 118.2 9.6 19.8 16.0 8.2 22.4 7.8 9.1 8.3 7.7 14.5 9.1 7.7 7.8 29.6 7.8 25.4 8.3 13.0 9.0 12.4 16.1 18.0 15.4 14.0 15.1 14.7 17.5 16.7 14.7 15.5 17.6 23.3 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 17.7 20.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 16.8 10.5 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 27.8 3.8 0.0 0.0 0.0 CHMP3 "CGI-149, NEDF, VPS24" ENSG00000115561 "Charged multivesicular body protein 3" Q9Y3E7 2 86503430-86563479 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA015673, HPA073383" Supported NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA015673: AB_1858761, HPA073383: AB_2732224" "unprognostic (2.49e-3)" "unprognostic (1.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (3.92e-5)" "unprognostic (2.67e-1)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "prognostic unfavorable (7.39e-4)" "unprognostic (1.20e-1)" "prognostic favorable (5.32e-4)" "unprognostic (1.34e-1)" "unprognostic (8.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.64e-1)" 70.0 56.1 39.5 41.0 54.3 30.9 64.2 49.3 45.6 57.9 26.1 72.3 63.1 68.8 56.9 93.0 51.8 54.8 100.2 46.3 39.9 59.9 23.3 64.0 34.0 35.9 36.5 49.0 66.7 70.3 33.1 31.8 37.1 64.3 75.9 30.8 52.9 61.9 97.1 58.6 64.5 73.4 38.7 40.3 60.5 34.2 42.5 31.7 68.0 80.9 39.9 70.2 50.6 38.1 105.3 96.1 54.4 39.6 71.2 136.7 52.5 76.7 103.2 64.4 55.6 86.2 90.2 34.3 71.7 97.7 71.8 82.8 33.3 67.0 70.3 21.0 42.5 45.5 45.5 98.8 62.5 36.4 47.7 82.4 147.7 40.8 64.9 70.4 73.1 34.1 49.1 25.3 104.7 90.7 24.4 32.4 18.8 138.9 73.8 15.3 125.2 27.2 85.7 117.3 65.7 71.4 73.3 68.0 66.1 25.8 58.3 55.7 88.7 114.2 46.8 112.2 86.7 21.0 33.1 22.9 81.5 58.0 61.3 158.5 61.5 171.5 28.0 73.8 33.6 49.5 41.8 33.8 49.9 49.3 48.7 37.9 228.7 35.5 66.5 42.1 46.1 54.4 39.5 54.3 49.3 45.6 46.3 39.9 35.9 36.5 37.1 38.7 42.5 38.1 102.5 147.4 93.5 0.0 49.6 95.3 83.3 94.4 83.6 55.7 115.2 72.6 125.2 147.3 111.4 40.5 41.7 51.1 42.7 222.1 148.7 180.7 206.6 46.7 84.9 96.2 133.5 73.0 0.0 174.8 59.2 67.4 58.6 70.4 147.6 30.0 144.5 59.1 89.5 69.0 0.0 159.2 65.1 126.2 48.4 108.5 71.7 77.2 71.2 0.0 93.6 60.5 78.2 0.0 0.0 186.7 219.4 91.0 25.0 95.9 201.1 173.3 76.1 42.4 65.7 73.6 78.5 100.7 57.3 101.9 94.1 85.0 47.5 57.3 165.4 103.4 CHURC1 "C14orf52, FLJ33064, My015" ENSG00000258289 "Churchill domain containing 1" Q8WUH1 14 64914361-64944591 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040072 Approved Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA040072: AB_10963788" "unprognostic (2.94e-1)" "unprognostic (2.42e-1)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.80e-1)" "unprognostic (2.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.64e-2)" "unprognostic (4.64e-1)" "unprognostic (6.78e-3)" "unprognostic (2.12e-1)" "unprognostic (1.99e-1)" "unprognostic (3.51e-2)" "unprognostic (6.67e-2)" "unprognostic (3.04e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" 47.8 42.0 29.9 39.1 34.8 43.8 37.4 34.5 41.2 41.2 27.2 43.8 30.9 40.0 32.6 34.3 34.2 32.5 58.8 29.8 33.7 34.7 52.4 29.3 43.8 38.8 33.3 43.9 30.2 46.1 25.2 34.5 38.6 32.4 36.4 35.7 26.5 37.7 82.9 30.1 33.9 45.8 34.7 42.2 33.7 25.4 34.3 61.2 32.9 53.0 43.3 38.3 30.5 40.3 119.6 61.8 58.8 43.7 70.1 75.6 68.9 85.3 74.3 47.4 53.9 34.1 75.1 69.9 57.7 73.7 75.2 84.9 51.7 69.2 51.8 79.7 25.3 67.9 47.7 79.3 66.1 37.7 64.9 89.9 50.5 43.0 81.4 79.7 51.6 107.2 30.6 60.5 58.1 97.6 72.7 61.6 31.4 140.9 101.1 63.4 63.2 42.6 64.5 83.8 30.0 36.7 57.6 59.8 81.0 53.7 101.8 78.4 64.8 41.3 87.8 45.0 56.0 49.5 46.8 162.0 43.0 44.6 51.8 201.6 131.9 145.4 111.5 137.6 128.2 161.8 167.5 134.1 107.4 135.9 166.3 139.8 292.8 122.4 138.3 154.7 238.5 143.5 29.9 34.8 34.5 41.2 29.8 33.7 38.8 33.3 38.6 34.7 34.3 40.3 154.6 102.5 89.0 0.0 128.2 58.5 73.8 176.8 130.3 73.8 85.0 98.7 53.4 94.4 98.2 99.3 43.8 90.4 97.9 89.3 131.0 160.7 82.0 130.8 87.3 109.9 89.8 91.5 0.0 222.7 89.7 100.9 75.4 80.8 95.6 69.6 127.5 190.4 89.3 53.8 0.0 100.3 107.8 172.6 69.6 27.1 104.1 130.5 83.6 0.0 214.3 155.2 132.8 0.0 0.0 216.8 118.9 121.5 79.7 70.5 124.6 211.0 145.1 87.2 131.5 100.6 135.7 131.1 81.1 158.3 65.9 89.8 137.0 205.8 121.1 72.2 CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 262.4" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 74.8;Cytotrophoblasts: 116.5;Extravillous trophoblasts: 100.6;Hofbauer cells: 218.2;Syncytiotrophoblasts: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA040459: AB_10796456, HPA063729: AB_2685105" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (6.59e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.07e-2)" "unprognostic (4.06e-3)" "unprognostic (5.02e-2)" "unprognostic (7.16e-2)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-3)" "unprognostic (8.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-2)" 27.8 68.6 23.1 53.6 26.0 70.7 48.5 25.7 26.7 31.5 39.1 82.8 107.9 22.6 41.1 30.1 32.1 43.0 78.0 22.0 24.6 81.3 262.4 43.4 105.3 26.1 24.0 20.6 59.8 75.5 24.6 65.5 26.6 39.1 68.4 24.7 44.0 26.8 125.5 19.4 86.8 23.8 26.4 52.8 68.8 20.7 26.9 60.3 80.2 97.4 66.9 46.3 20.3 32.0 114.6 168.6 104.3 71.7 91.7 110.7 61.2 92.7 105.4 120.2 133.5 157.7 172.9 186.9 157.4 56.2 155.7 118.3 197.9 90.2 95.4 171.3 124.2 156.2 137.7 161.2 70.7 240.5 123.1 90.8 87.2 76.7 67.6 84.5 130.1 118.5 222.3 148.8 89.5 197.8 100.1 202.8 144.6 148.9 96.3 154.5 139.8 410.4 154.3 127.0 112.2 87.5 76.8 150.9 180.6 113.9 120.6 243.6 83.0 98.2 129.4 104.7 193.6 144.4 353.8 186.4 109.5 429.3 96.9 122.4 255.8 117.0 67.3 254.1 83.0 346.0 94.8 88.1 231.6 345.5 75.5 74.4 132.0 86.9 228.3 386.5 146.1 269.0 23.1 26.0 25.7 26.7 22.0 24.6 26.1 24.0 26.6 26.4 26.9 32.0 10.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 0.0 116.5 10.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 100.6 13.2 0.0 0.0 0.0 0.0 0.0 0.0 218.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 88.8 2.0 0.0 0.0 0.0 CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 82.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 716.1;Proximal enterocytes: 539.1;Proximal tubular cells: 726.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" 5.2 10.1 10.0 6.3 9.8 0.9 5.9 10.4 13.6 6.6 11.8 9.7 22.7 5.6 3.4 11.2 6.1 7.2 43.0 10.1 12.7 26.4 16.6 4.3 6.1 10.1 9.9 6.8 5.3 82.3 5.8 5.5 11.2 7.6 8.8 8.2 9.9 7.1 46.4 8.4 21.8 8.0 9.5 4.6 7.2 2.8 9.6 6.5 10.1 49.9 5.9 7.8 3.0 8.9 20.5 10.2 8.0 14.6 10.5 11.6 4.7 16.9 19.2 16.4 22.5 24.1 18.8 36.1 13.9 17.5 9.6 12.9 21.7 15.1 14.7 16.2 29.4 9.5 16.4 19.6 11.9 17.0 7.1 14.6 12.1 15.7 23.9 13.9 19.5 17.9 21.2 16.5 11.6 6.8 14.6 18.2 8.5 15.5 31.4 11.0 29.3 19.0 22.1 7.1 25.0 9.0 12.9 34.1 12.4 7.0 22.7 9.0 19.3 7.1 12.8 20.5 20.4 16.6 29.0 27.2 18.9 16.6 7.0 0.0 4.5 0.2 4.3 3.4 5.3 6.3 4.9 5.0 7.6 5.4 5.7 5.7 2.3 5.4 2.3 5.0 6.8 4.2 10.0 9.8 10.4 13.6 10.1 12.7 10.1 9.9 11.2 9.5 9.6 8.9 31.4 60.9 45.7 27.4 33.0 128.7 87.3 309.4 78.0 84.6 46.4 61.1 321.6 97.2 180.2 134.3 43.8 174.8 22.7 71.1 716.1 98.0 240.9 42.8 30.4 61.6 225.4 24.8 47.2 82.1 78.5 52.7 38.2 43.8 34.3 23.0 63.9 249.6 68.6 42.1 53.1 141.9 272.6 37.0 37.9 366.1 42.3 31.0 183.2 21.5 34.0 47.2 44.3 36.7 30.9 83.2 121.9 40.3 31.7 109.1 539.1 726.8 138.6 56.3 32.9 50.1 55.6 159.4 65.6 94.9 114.2 72.7 26.2 65.0 147.3 69.4 CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422669 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.1" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 479.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Supported "Microtubule ends,Cytosol" NA NA 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Microtubule ends, Cytosol" "CAB004399: AB_671001, HPA026678: AB_1846954" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (6.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (2.51e-1)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (8.97e-2)" "unprognostic (3.26e-2)" "unprognostic (5.50e-2)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (2.52e-3)" 29.6 36.7 22.5 27.8 23.5 18.0 23.2 63.0 24.4 22.8 18.3 34.1 16.9 26.2 18.0 70.8 17.0 22.3 43.1 24.4 24.0 29.7 46.2 28.1 18.4 19.0 22.5 13.1 26.8 90.1 16.4 38.9 17.7 32.5 20.6 26.9 25.2 44.4 165.4 41.3 19.7 42.4 15.7 17.3 19.6 24.8 23.3 13.9 69.5 169.1 25.2 48.3 29.8 24.3 54.2 63.5 46.0 39.1 34.8 51.7 79.4 76.3 69.2 49.2 30.0 31.7 24.4 24.2 49.8 95.7 66.9 65.6 29.7 31.2 57.9 95.0 17.0 7.7 40.2 36.3 68.6 27.8 41.5 32.1 103.3 57.0 87.6 70.3 49.2 20.2 29.4 15.0 47.7 34.6 17.4 8.7 16.7 25.7 53.2 14.7 31.5 11.6 45.5 61.9 16.1 10.7 162.9 39.5 64.0 44.9 31.4 15.9 98.2 36.8 40.1 84.3 49.3 17.0 14.4 14.1 63.0 14.0 25.6 3.3 6.5 4.0 6.6 10.6 5.1 4.9 6.1 5.9 5.6 3.0 4.5 3.2 17.1 4.7 9.4 3.2 6.3 4.1 22.5 23.5 63.0 24.4 24.4 24.0 19.0 22.5 17.7 15.7 23.3 24.3 50.2 134.6 129.9 116.2 32.4 67.2 162.6 42.4 23.9 69.6 50.0 30.1 142.2 50.1 106.5 44.1 43.8 129.7 34.5 38.0 7.9 69.0 156.9 101.2 53.1 57.3 13.9 11.3 115.3 65.5 32.9 69.1 26.0 115.0 72.7 41.3 46.4 48.3 38.3 132.9 107.7 22.3 42.7 41.8 48.5 82.9 35.8 57.0 55.2 45.0 54.2 34.8 46.4 45.2 40.7 95.6 28.5 62.1 33.0 134.4 26.4 13.2 146.5 41.8 72.3 114.6 68.4 22.0 27.4 40.3 143.3 479.4 48.5 39.6 23.0 223.9 CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99897134 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.7" "Cell type enhanced" "Detected in many" "Astrocytes: 84.9;Distal tubular cells: 138.9;Hepatocytes: 84.1;Proximal tubular cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 56.1;SCLC-21H: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 7300 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 7.1 16.2 11.4 5.5 11.8 5.1 10.5 24.4 12.7 7.7 35.3 20.6 25.0 6.5 13.0 11.3 7.9 6.9 22.6 12.6 8.6 66.0 109.7 5.6 10.4 9.1 9.0 5.7 9.8 14.4 6.7 3.7 7.3 6.9 21.9 7.3 12.3 8.9 43.3 9.3 23.5 6.4 5.6 8.6 8.7 9.3 10.7 5.8 12.3 69.5 10.8 7.4 6.9 8.8 0.4 2.3 16.6 7.5 7.6 7.0 3.6 0.8 1.6 1.4 2.6 0.3 12.4 3.0 4.8 1.0 3.2 3.9 1.5 2.8 1.8 15.3 2.4 19.2 4.9 11.8 5.2 10.4 1.3 3.8 8.3 0.2 6.4 1.6 2.2 15.7 2.7 9.8 1.6 4.3 4.7 14.3 10.8 56.1 3.4 6.0 0.7 7.1 16.6 1.1 53.1 8.1 3.4 3.8 3.6 5.9 8.0 13.2 0.3 0.7 1.9 1.4 2.7 22.3 4.7 0.6 11.3 14.9 2.3 1.7 4.5 0.5 9.9 10.0 12.0 14.5 17.4 13.9 9.4 15.7 13.3 15.8 0.6 14.2 4.8 10.3 24.2 7.7 11.4 11.8 24.4 12.7 12.6 8.6 9.1 9.0 7.3 5.6 10.7 8.8 7.4 6.4 5.0 84.9 8.6 5.5 9.1 18.4 8.6 2.3 8.9 11.3 36.1 21.5 10.9 14.7 2.1 14.3 9.2 17.9 138.9 11.6 1.6 6.1 4.1 6.2 1.2 2.5 30.6 8.1 3.2 5.9 5.6 4.4 6.3 7.1 4.6 84.1 7.6 0.0 25.6 11.5 10.2 6.7 4.5 4.8 2.1 5.4 16.0 48.7 4.4 6.5 7.2 21.6 9.5 4.0 13.8 4.1 3.8 4.3 23.1 144.7 4.1 5.0 0.0 7.6 18.1 3.0 10.5 6.9 6.3 7.4 8.3 13.6 19.1 6.7 CMBL FLJ23617 ENSG00000164237 "Carboxymethylenebutenolidase homolog" Q96DG6 5 10275875-10307902 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 172.4;skeletal muscle: 164.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 185.2;Distal tubular cells: 215.2;Proximal enterocytes: 716.0;Proximal tubular cells: 465.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 48.5;K-562: 51.4;PC-3: 46.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036571 Uncertain NA NA 580000 "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036571: AB_10670114" "unprognostic (1.81e-2)" "unprognostic (2.55e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.20e-1)" "unprognostic (8.64e-2)" "prognostic favorable (1.99e-4)" "unprognostic (1.76e-1)" "unprognostic (4.44e-2)" "unprognostic (1.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.44e-1)" 11.3 31.5 8.9 3.8 8.7 4.0 10.6 7.2 10.2 7.2 8.1 53.6 95.8 8.5 9.9 3.8 13.5 14.2 22.9 8.5 8.5 168.5 172.4 6.8 1.2 8.5 8.9 23.3 16.6 26.6 10.6 2.1 9.0 14.3 34.7 1.3 9.6 7.4 164.4 2.8 85.0 6.4 8.0 2.7 28.5 3.2 10.0 2.9 9.8 42.4 0.5 9.7 6.4 7.7 5.9 7.2 8.2 20.3 32.0 35.7 41.2 9.7 11.1 3.0 4.5 3.0 30.9 0.1 15.4 7.8 14.5 0.1 19.7 12.8 4.1 0.3 13.4 27.4 28.6 24.3 9.8 0.2 0.2 48.5 8.5 6.7 6.1 11.7 9.4 0.0 51.4 0.4 11.6 1.3 0.1 1.1 12.1 0.0 46.0 5.9 0.0 0.6 32.2 3.8 6.3 9.7 23.1 2.2 0.7 9.7 16.7 1.0 2.7 4.6 6.0 7.6 0.1 0.2 0.1 0.1 8.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 8.9 8.7 7.2 10.2 8.5 8.5 8.5 8.9 9.0 8.0 10.0 7.7 4.0 25.6 17.2 2.9 2.2 3.7 17.8 6.3 14.8 2.0 40.1 16.8 86.0 55.8 14.8 23.9 4.2 15.3 0.9 185.2 215.2 10.7 3.2 26.5 25.8 7.1 19.2 56.1 5.0 15.6 10.6 37.1 133.0 19.2 13.3 47.4 14.3 161.2 12.1 0.0 6.9 100.5 2.0 4.1 3.8 3.5 47.8 5.5 1.8 1.9 0.4 17.5 1.0 4.0 0.4 16.1 118.6 41.3 0.5 17.5 716.0 465.4 13.0 3.1 0.0 31.0 12.7 1.0 5.9 5.2 3.8 4.9 4.4 145.0 162.7 15.6 COMMD3 "BUP, C10orf8" ENSG00000148444 "COMM domain containing 3" Q9UBI1 10 22316386-22320306 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 432.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 307.8;U-937: 403.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036584 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036584: AB_10670803" "unprognostic (3.11e-2)" "unprognostic (5.97e-3)" "unprognostic (6.43e-2)" "unprognostic (2.44e-1)" "unprognostic (7.42e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (5.46e-7)" "unprognostic (1.03e-3)" "unprognostic (1.57e-1)" "unprognostic (1.58e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "unprognostic (2.68e-3)" "unprognostic (1.70e-1)" "unprognostic (3.35e-1)" "unprognostic (5.71e-2)" "unprognostic (2.88e-3)" 30.9 35.3 33.3 38.3 35.7 38.1 52.6 36.8 45.0 29.1 33.9 38.2 37.5 31.0 47.8 38.1 34.6 32.9 79.8 34.7 35.8 38.7 62.8 28.2 45.4 36.3 34.2 23.4 51.7 53.5 24.9 22.8 35.6 36.7 36.8 29.5 51.8 30.7 75.4 36.6 36.8 38.9 37.0 32.5 33.0 32.1 33.7 61.2 33.1 76.2 43.4 39.6 21.0 41.0 53.8 65.0 23.5 14.4 91.0 97.0 22.7 48.1 48.3 45.8 60.4 16.9 77.8 61.6 47.7 58.8 41.8 33.4 37.8 68.5 34.8 307.8 44.1 80.2 23.1 62.7 87.8 29.0 66.5 86.3 74.6 35.7 35.2 67.8 92.5 93.7 55.0 70.6 103.5 47.8 126.2 29.6 5.7 69.0 101.5 54.9 57.5 89.0 64.8 30.2 14.4 54.3 38.1 71.8 85.8 20.2 48.8 199.1 82.4 30.3 77.3 73.0 42.1 94.4 93.0 63.9 67.5 403.0 28.7 154.6 98.0 73.1 48.5 97.8 56.8 93.2 63.3 52.0 117.8 85.2 39.9 48.8 15.2 83.2 87.6 140.3 83.2 118.3 33.3 35.7 36.8 45.0 34.7 35.8 36.3 34.2 35.6 37.0 33.7 41.0 37.6 41.7 31.7 0.0 59.0 38.2 48.4 148.4 18.2 42.0 52.7 82.5 98.8 30.0 73.0 33.1 14.6 61.0 55.2 20.9 117.4 83.0 432.9 42.2 35.7 37.9 41.3 69.2 0.0 82.9 53.4 42.6 19.4 27.4 54.5 43.7 30.7 61.5 99.0 45.4 0.0 43.4 118.0 51.8 48.3 97.0 58.7 47.6 53.4 0.0 103.6 71.4 52.5 0.0 0.0 67.0 36.7 56.8 63.2 29.1 67.1 102.2 72.1 65.2 46.0 45.7 66.6 35.6 42.9 20.5 51.1 26.1 34.7 51.4 40.7 44.7 COPS4 CSN4 ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 100000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA036894: AB_10670929, HPA042828: AB_2678191" "unprognostic (1.82e-3)" "unprognostic (1.01e-2)" "prognostic favorable (4.14e-4)" "unprognostic (7.97e-3)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-1)" "unprognostic (3.10e-2)" "unprognostic (9.21e-2)" "prognostic favorable (5.21e-6)" "unprognostic (5.84e-2)" "unprognostic (3.07e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" 25.6 38.6 28.4 22.0 30.7 41.0 32.0 26.9 33.5 31.7 26.0 27.4 23.1 30.8 28.8 30.5 26.0 22.5 59.7 30.6 35.0 38.8 29.2 22.2 29.9 28.4 29.9 31.9 24.6 43.7 39.2 30.2 32.0 30.3 25.1 45.6 23.7 30.5 104.8 26.7 22.0 33.3 28.7 22.5 22.4 45.0 30.8 36.2 38.4 84.1 32.7 31.8 23.5 28.9 51.7 30.4 64.1 59.0 56.0 71.7 34.8 67.2 85.7 74.8 66.0 43.7 51.8 86.9 57.3 140.5 41.3 37.7 80.6 68.9 101.1 55.6 56.9 50.4 43.5 42.1 46.3 86.8 135.6 54.4 47.0 55.8 47.8 56.2 101.1 53.5 65.2 48.0 91.9 43.4 105.0 63.6 35.3 81.1 40.6 74.0 48.8 48.1 59.8 47.2 67.7 39.6 45.0 69.4 43.5 43.8 52.7 46.4 66.7 52.2 55.1 39.7 48.6 49.8 32.7 96.8 50.3 55.2 52.8 91.4 37.0 55.2 43.0 50.4 53.9 39.7 47.1 49.7 45.3 38.9 44.7 48.1 8.2 54.6 59.8 29.0 47.6 52.3 28.4 30.7 26.9 33.5 30.6 35.0 28.4 29.9 32.0 28.7 30.8 28.9 25.6 12.8 20.1 21.9 34.1 42.8 42.2 94.5 23.3 38.7 20.1 23.4 81.3 20.0 51.5 20.2 31.3 82.5 36.5 14.5 90.1 42.4 130.6 24.9 27.6 31.9 31.2 26.5 34.7 33.2 62.7 39.9 15.3 21.3 34.2 38.2 20.0 22.4 49.0 26.9 32.9 22.0 67.1 29.2 29.2 38.3 30.7 27.2 33.8 18.7 37.8 62.5 37.0 28.6 32.9 28.2 22.1 42.9 28.6 20.5 22.6 75.7 37.9 44.6 32.9 34.1 42.5 121.2 50.2 29.7 35.2 95.0 32.8 53.3 26.3 34.3 COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051371: AB_2681459" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.75e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.45e-3)" "unprognostic (2.90e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.19e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" 11.2 38.4 10.5 5.6 11.0 5.5 12.0 10.9 13.1 12.1 15.5 13.0 10.2 10.0 11.3 10.1 10.5 6.7 32.0 10.8 11.1 23.0 25.7 7.4 6.3 10.6 10.6 11.5 7.0 25.1 15.9 8.0 10.6 12.6 9.5 5.8 11.1 9.9 38.6 9.3 10.8 9.8 10.7 11.3 13.4 22.0 11.0 7.3 12.3 42.6 7.0 13.6 10.5 11.1 12.2 21.7 11.1 25.7 13.2 10.7 15.4 14.8 13.6 21.8 18.4 16.4 21.0 10.7 13.7 15.3 15.0 19.1 16.6 14.8 20.6 16.3 13.3 7.2 12.8 14.3 18.0 7.2 24.9 18.1 19.2 19.9 19.5 14.1 13.9 21.5 6.4 9.6 19.2 33.3 12.4 11.7 4.0 24.8 26.0 11.7 14.1 7.6 22.9 15.2 16.6 8.8 25.2 21.5 14.6 7.2 36.4 13.3 9.4 24.8 22.9 19.0 10.8 8.9 9.0 9.0 13.7 10.6 17.1 5.4 11.3 9.2 11.3 14.2 11.3 10.3 11.2 11.3 12.1 5.3 15.6 9.4 2.3 14.5 13.1 8.9 7.6 8.5 10.5 11.0 10.9 13.1 10.8 11.1 10.6 10.6 10.6 10.7 11.0 11.1 11.9 25.6 25.5 6.2 11.4 4.7 8.1 26.9 6.8 18.9 12.3 12.4 10.3 11.5 23.1 12.9 12.5 26.3 4.1 8.3 19.6 10.8 167.0 14.1 11.0 9.1 4.8 7.4 10.0 10.9 12.6 11.9 12.2 9.9 25.3 13.9 11.4 14.7 16.2 20.2 10.0 9.7 20.3 5.4 4.2 49.5 10.8 7.5 10.6 3.7 9.6 12.0 15.5 5.0 8.4 8.6 8.4 12.4 10.6 6.0 23.3 41.3 15.8 28.1 19.7 10.5 20.5 24.7 21.0 11.5 6.0 23.8 11.9 39.9 9.4 7.1 COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" 10.2 13.6 10.7 7.0 11.2 4.8 13.4 10.9 11.6 10.8 12.5 14.1 12.4 15.6 12.3 12.4 15.5 10.7 23.4 11.0 10.8 14.1 12.3 10.0 8.3 10.6 11.3 20.0 10.3 24.4 9.7 10.0 11.1 17.7 13.2 14.0 10.4 14.7 45.8 7.9 11.8 11.6 10.4 10.0 12.8 20.9 11.3 10.3 16.2 44.9 8.4 10.3 8.8 13.1 23.5 24.8 21.1 12.4 11.6 12.2 17.7 13.5 11.0 18.0 18.5 15.9 19.1 17.8 63.9 10.4 19.4 24.5 29.6 16.9 13.0 15.2 29.9 9.5 22.8 49.3 14.4 22.9 20.1 10.3 14.6 16.8 12.2 14.8 14.8 20.9 26.4 16.2 12.9 42.4 24.0 18.4 16.1 9.1 13.1 29.0 23.3 22.8 15.7 15.5 30.4 17.4 12.6 27.4 16.2 10.2 25.2 30.7 16.3 19.0 10.9 14.1 19.7 15.0 26.2 19.7 20.4 13.1 12.5 40.4 11.4 17.8 9.9 10.6 9.4 16.3 8.9 8.7 12.6 15.3 12.2 10.8 126.5 12.9 12.3 15.6 6.2 5.6 10.7 11.2 10.9 11.6 11.0 10.8 10.6 11.3 11.1 10.4 11.3 13.1 13.3 16.0 12.6 6.2 35.5 11.0 26.3 20.9 13.6 31.2 18.3 21.1 21.8 31.5 14.9 16.5 39.6 21.2 28.7 38.1 45.0 25.2 14.8 23.7 16.2 16.1 24.0 4.8 6.0 18.0 17.9 14.9 32.1 23.2 25.4 31.1 20.7 11.1 23.3 20.2 8.8 39.0 30.5 29.4 12.9 8.5 18.6 18.8 10.6 4.7 11.6 39.5 8.2 5.0 9.4 13.2 30.4 13.9 11.6 17.8 71.5 23.7 24.4 53.9 19.7 20.0 20.2 81.3 53.1 12.8 12.4 32.2 23.9 38.2 39.8 24.0 COQ9 "C16orf49, DKFZP434K046" ENSG00000088682 "Coenzyme Q9" O75208 16 57447425-57461270 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 255.4;tongue: 241.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 217.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040918 Supported Approved Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Mitochondria, Cytosol" "HPA040918: AB_10794154" "unprognostic (9.18e-2)" "unprognostic (3.60e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-2)" "unprognostic (2.14e-3)" "unprognostic (2.57e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-1)" "unprognostic (2.59e-1)" "unprognostic (9.78e-2)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.03e-11)" "unprognostic (7.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.23e-2)" 24.3 44.7 21.7 15.1 22.7 10.6 18.0 23.4 26.1 19.6 38.4 48.6 47.3 16.8 16.6 40.0 24.0 19.4 139.7 21.2 22.1 61.3 53.2 14.4 15.6 21.5 21.8 16.6 27.9 79.7 14.9 16.7 20.7 26.2 38.2 11.8 44.1 28.8 255.4 25.2 41.8 28.3 21.3 12.2 35.3 23.8 24.3 18.7 29.2 241.0 17.3 38.2 21.6 21.7 33.6 67.2 18.3 45.8 36.0 27.3 21.3 31.9 25.3 44.8 24.9 41.2 43.0 40.3 59.0 28.8 34.3 70.5 52.8 56.6 28.3 21.4 49.3 27.7 44.2 66.1 39.8 36.1 44.4 45.6 73.7 35.9 68.1 29.8 51.1 35.6 54.7 18.1 27.4 48.6 30.5 26.8 29.6 74.4 90.6 60.8 58.7 104.8 71.3 37.4 56.3 56.7 108.4 103.8 54.9 16.1 59.4 39.5 34.4 32.4 38.9 34.8 40.4 42.9 29.5 48.0 44.4 51.2 37.3 21.0 28.2 23.0 19.5 36.6 20.1 18.8 16.6 17.1 34.4 19.1 17.7 26.0 8.9 24.0 38.2 21.5 25.5 21.9 21.7 22.7 23.4 26.1 21.2 22.1 21.5 21.8 20.7 21.3 24.3 21.7 17.1 12.8 18.9 37.9 15.7 8.4 17.1 55.3 19.9 16.2 21.7 23.1 79.5 45.8 28.7 25.8 16.7 74.7 14.2 68.8 217.2 53.9 37.9 20.4 17.3 17.3 27.6 21.2 21.2 29.3 25.6 20.7 35.7 18.0 7.0 40.7 18.5 53.6 38.8 20.2 24.0 46.6 83.4 16.3 5.4 28.4 21.1 14.1 28.4 7.5 22.7 29.1 14.4 20.6 14.5 27.2 37.0 20.3 15.9 21.5 90.7 114.1 30.0 24.0 13.1 22.6 19.8 66.0 38.8 37.3 11.2 78.7 12.8 91.2 70.2 18.4 COX10 ENSG00000006695 "Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10" Q12887 17 14069490-14231736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Heme biosynthesis" Transferase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 44.5;tongue: 44.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 88.2;Late spermatids: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032005, HPA032006" Supported Supported Nucleoli,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Nucleoli, Cytosol" "HPA032005: AB_10603560, HPA032006: AB_10670554" "unprognostic (6.17e-2)" "unprognostic (3.14e-1)" "unprognostic (1.41e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.40e-2)" "unprognostic (6.27e-3)" "unprognostic (1.07e-1)" "unprognostic (9.46e-3)" "unprognostic (6.46e-2)" "prognostic favorable (4.32e-6)" "prognostic favorable (8.73e-4)" "unprognostic (8.82e-2)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" 7.1 7.5 3.1 5.4 2.9 10.4 6.0 4.1 4.4 5.8 4.3 12.5 12.5 5.2 4.4 10.9 5.6 4.2 27.9 3.3 3.9 11.6 10.6 4.4 5.8 3.8 3.5 4.5 9.9 9.6 3.3 7.0 3.5 5.6 12.3 5.6 7.2 5.5 44.5 7.4 10.1 7.2 3.0 4.8 9.3 21.1 4.0 5.4 6.2 44.3 7.5 8.5 6.6 3.6 10.1 19.7 7.7 11.9 7.7 5.6 19.5 12.3 8.4 21.9 14.6 16.3 6.6 23.5 9.8 13.0 6.8 20.2 16.6 16.3 17.3 13.1 15.7 14.5 12.4 20.0 14.2 15.5 12.3 9.8 19.5 14.0 17.6 7.9 11.4 15.8 20.4 8.2 9.5 13.1 13.5 10.5 12.8 37.6 9.5 10.3 28.8 18.5 15.2 20.1 5.2 9.8 12.0 18.5 16.5 36.1 9.6 9.2 9.9 8.9 8.0 9.9 15.8 10.1 15.6 11.2 14.9 15.7 11.9 3.8 11.3 4.4 9.8 16.1 10.6 13.2 11.3 10.5 14.9 9.2 11.9 11.5 1.2 10.0 13.9 4.6 20.1 11.0 3.1 2.9 4.1 4.4 3.3 3.9 3.8 3.5 3.5 3.0 4.0 3.6 5.9 0.0 14.7 25.8 9.6 9.7 9.5 9.8 14.2 7.5 8.7 7.4 88.2 5.7 7.3 11.0 10.4 19.7 5.7 13.8 41.1 9.1 41.1 9.6 9.6 7.8 12.6 13.3 33.5 8.7 17.5 8.8 16.3 9.4 5.1 7.5 3.9 9.6 10.8 0.0 43.0 16.4 8.2 4.4 4.7 81.0 2.1 6.7 5.4 22.5 6.3 4.6 8.2 34.7 26.9 8.8 11.4 6.8 12.5 8.7 26.6 17.8 5.8 12.2 0.0 5.2 12.5 22.8 19.2 19.4 10.4 16.1 8.6 6.6 18.9 13.7 COX5A ENSG00000178741 "Cytochrome c oxidase subunit 5A" P20674 15 74919791-74938083 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1749.5;skeletal muscle: 1609.7;tongue: 1735.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1645.3;Distal tubular cells: 1475.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027526 Supported NA NA 530000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA027526: AB_10602802" "unprognostic (7.32e-2)" "prognostic favorable (2.15e-4)" "unprognostic (4.06e-2)" "unprognostic (9.85e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (3.79e-2)" "unprognostic (9.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.77e-1)" "unprognostic (8.62e-2)" "prognostic favorable (6.06e-7)" "unprognostic (9.78e-2)" "unprognostic (2.22e-1)" "unprognostic (1.30e-1)" "unprognostic (3.81e-3)" 175.6 176.7 187.1 105.1 189.5 148.5 150.8 231.1 258.1 109.8 201.3 454.2 326.9 98.2 110.7 293.0 89.3 67.8 1749.5 193.1 229.3 373.5 349.6 133.0 125.6 216.1 207.5 71.1 259.3 385.3 141.1 88.0 208.8 118.4 398.2 194.1 211.2 99.2 1609.7 169.0 269.6 95.0 194.8 150.8 306.8 217.8 220.4 150.7 141.5 1735.8 197.9 141.2 146.3 193.8 300.4 309.1 376.8 331.1 227.2 260.2 443.1 262.7 222.3 317.7 294.8 346.0 352.1 700.0 322.0 219.5 387.8 567.7 898.3 368.4 263.7 401.0 906.2 566.6 299.7 436.0 283.9 642.7 335.0 266.6 389.9 198.3 445.1 217.4 377.7 450.0 522.2 429.9 321.2 222.4 558.8 494.6 408.7 575.8 540.1 499.0 369.7 778.4 469.8 472.4 570.5 250.1 396.6 569.2 871.3 407.6 286.3 507.6 274.3 241.4 238.7 303.9 421.1 508.4 1000.3 759.0 258.2 836.1 224.5 332.4 361.5 210.2 198.1 465.6 238.6 296.4 242.4 235.7 452.9 227.3 171.6 198.0 87.4 354.9 432.7 365.2 372.6 426.4 187.1 189.5 231.1 258.1 193.1 229.3 216.1 207.5 208.8 194.8 220.4 193.8 120.7 99.3 119.6 20.5 166.6 158.2 235.3 623.6 151.4 113.4 202.6 313.4 1645.3 221.6 324.0 171.0 39.6 502.8 162.7 987.6 1475.2 407.5 1046.3 199.4 124.3 163.8 461.4 227.3 18.9 436.7 528.2 156.3 247.2 192.8 104.0 143.3 117.8 471.8 571.5 92.5 25.1 890.5 496.4 286.0 209.1 819.6 100.3 238.6 250.8 17.8 413.7 159.9 162.7 15.6 20.2 412.1 817.3 85.7 350.7 319.3 1276.3 921.7 242.7 176.8 92.1 139.6 590.9 523.0 253.6 371.3 159.0 511.0 144.2 216.5 1045.6 393.3 CRADD RAIDD ENSG00000169372 "CASP2 and RIPK1 domain containing adaptor with death domain" P78560 12 93677375-93894840 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.3;Early spermatids: 164.5;Inhibitory neurons: 122.3;Oligodendrocyte precursor cells: 174.4;Oligodendrocytes: 287.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005337 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Nucleoplasm "CAB005337: AB_2085481" "unprognostic (1.07e-2)" "prognostic favorable (9.06e-5)" "unprognostic (9.65e-3)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (3.10e-1)" "unprognostic (3.79e-2)" "unprognostic (8.99e-2)" "unprognostic (1.54e-1)" "unprognostic (7.89e-2)" "unprognostic (6.06e-2)" "unprognostic (3.18e-2)" "prognostic favorable (4.04e-9)" "unprognostic (2.57e-2)" "unprognostic (6.86e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-2)" 10.0 19.3 9.1 5.0 10.5 9.3 11.2 9.9 9.1 12.8 12.8 13.6 16.9 13.0 12.6 13.0 9.9 10.4 41.2 8.7 10.1 17.9 37.3 9.9 7.3 9.7 9.9 10.3 12.7 18.6 15.3 7.2 9.8 11.4 8.2 12.8 11.0 8.9 28.2 11.4 18.0 8.2 8.7 10.4 12.9 13.7 10.0 13.3 9.6 30.0 6.2 12.7 11.3 10.3 7.8 17.4 8.4 9.6 11.8 21.2 10.6 8.8 10.7 7.6 8.9 16.4 3.2 13.9 5.3 10.2 5.8 8.0 9.3 11.5 9.3 14.7 12.3 7.4 7.0 12.2 12.2 6.8 6.8 19.8 17.4 12.2 9.5 8.0 9.3 15.2 21.3 6.4 9.1 12.6 10.1 12.3 10.6 8.9 13.2 16.8 4.3 19.3 7.4 5.7 12.9 12.5 12.0 11.7 21.3 8.1 20.5 13.2 10.0 17.5 8.7 8.4 9.0 15.0 8.7 12.9 8.2 10.0 8.4 62.7 11.6 45.5 23.8 14.7 21.1 15.1 16.5 24.8 9.7 13.5 17.6 13.0 33.9 20.6 23.2 13.1 20.9 12.0 9.1 10.5 9.9 9.1 8.7 10.1 9.7 9.9 9.8 8.7 10.0 10.3 7.8 9.6 6.3 161.3 7.8 7.4 9.3 21.1 6.2 6.4 8.9 7.2 38.7 7.2 18.0 7.3 8.4 14.5 9.0 19.1 23.5 16.8 164.5 11.8 8.7 11.9 7.8 9.1 62.8 22.4 12.7 10.3 10.2 6.7 4.5 3.7 10.0 41.9 11.5 23.5 122.3 14.6 26.4 10.6 6.1 35.2 17.7 16.0 3.6 96.5 9.5 16.9 15.5 174.4 287.2 19.5 19.8 23.7 8.4 10.1 58.5 63.1 20.0 15.5 6.6 15.0 11.4 25.6 11.7 10.1 8.1 10.8 10.2 8.3 13.9 10.1 CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006093-6040053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 169.5" "Cell type enhanced" "Detected in all" "Early spermatids: 264.2;Hepatocytes: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 237.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (8.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.89e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (9.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.83e-2)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "prognostic favorable (8.02e-4)" 50.1 55.1 14.7 16.9 14.9 28.4 33.2 14.4 17.9 24.0 16.7 32.3 59.2 18.9 19.9 18.5 24.1 19.9 82.8 14.5 14.7 57.8 169.5 27.1 16.5 15.5 15.9 21.2 37.4 28.3 15.8 17.9 15.3 32.6 32.9 15.5 27.5 25.8 86.0 15.1 40.9 23.7 15.3 14.5 46.5 27.8 16.9 16.9 27.2 79.5 18.3 25.8 17.7 15.4 71.7 46.5 27.9 40.0 83.1 74.9 34.5 43.6 50.9 38.8 46.8 61.5 44.4 75.8 31.4 52.6 73.3 45.0 54.6 70.9 57.6 21.9 39.9 99.5 17.0 237.4 59.6 99.7 32.4 44.6 59.4 41.5 73.5 36.8 57.3 40.3 76.4 31.6 44.2 25.9 63.6 90.1 55.4 154.8 42.4 42.3 44.6 80.7 61.8 22.1 50.3 43.4 44.8 98.7 78.1 27.5 35.8 59.6 39.2 45.9 33.4 48.7 59.0 33.8 79.1 79.9 17.6 79.5 43.9 0.0 1.2 0.6 1.2 0.9 2.2 2.3 0.7 0.8 1.3 1.1 1.4 0.8 0.0 1.7 0.5 1.6 0.8 0.4 14.7 14.9 14.4 17.9 14.5 14.7 15.5 15.9 15.3 15.3 16.9 15.4 18.8 22.4 47.6 22.2 26.4 33.8 41.4 19.4 31.9 12.9 35.8 27.7 108.0 64.3 16.2 36.8 4.2 45.1 19.5 36.3 64.6 27.9 264.2 29.7 26.2 22.7 28.6 58.0 37.0 28.8 64.1 33.8 52.0 29.7 14.7 31.6 22.5 208.7 34.2 11.8 28.7 50.7 4.1 40.0 24.1 99.5 30.4 31.9 26.6 32.8 28.9 40.5 25.7 39.7 34.3 28.4 49.1 24.5 41.8 117.7 75.7 141.0 15.0 12.9 13.1 29.2 25.6 23.0 18.4 37.7 27.8 36.3 23.3 32.3 82.9 48.6 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 36.1 32.6 20.9 38.6 23.2 34.0 35.9 28.2 29.6 36.5 29.3 48.3 39.1 35.8 26.6 50.0 39.9 31.3 54.0 25.7 21.0 41.0 31.8 31.6 41.2 20.6 21.1 41.5 46.9 59.1 21.2 42.4 21.1 35.8 40.7 32.9 41.1 37.7 110.5 34.2 40.5 39.1 18.8 30.2 49.5 65.2 22.3 51.6 39.6 86.4 46.6 47.4 28.5 27.3 209.5 170.4 152.9 96.0 61.1 103.8 103.5 117.9 116.1 125.8 139.5 178.5 120.0 179.1 74.2 90.1 179.1 147.8 162.1 167.4 187.2 62.6 57.7 247.3 44.7 177.7 102.5 228.1 51.3 99.5 173.3 105.8 316.0 122.2 139.5 146.4 248.9 112.6 123.8 64.2 262.0 73.7 227.4 173.4 97.6 149.8 140.5 140.9 112.9 128.5 163.9 132.3 97.2 184.0 174.8 120.7 120.4 83.9 142.7 136.0 118.4 90.0 178.5 120.6 311.8 174.1 65.8 119.5 138.6 40.5 23.8 28.7 18.2 32.3 22.4 23.0 18.0 17.6 31.5 22.5 17.9 17.4 14.9 25.1 33.5 25.7 20.4 20.8 20.9 23.2 28.2 29.6 25.7 21.0 20.6 21.1 21.1 18.8 22.3 27.3 50.7 64.1 84.6 51.9 46.1 41.0 40.0 43.8 45.5 49.4 42.1 36.1 59.4 41.5 75.8 44.1 31.3 42.2 50.5 43.5 41.1 68.5 135.5 67.6 77.0 44.5 35.2 59.3 65.6 50.6 54.4 46.3 40.2 75.7 63.8 108.6 27.1 31.1 33.2 60.6 69.3 41.8 46.8 39.2 30.3 140.0 41.0 45.3 14.2 51.5 61.7 38.6 37.0 73.9 73.6 66.6 34.4 36.9 49.6 57.2 43.2 68.8 65.5 27.8 52.6 43.6 56.8 94.2 68.7 52.3 50.2 61.4 38.9 81.2 40.6 59.4 CYB5RL LOC606495 ENSG00000215883 "Cytochrome b5 reductase like" Q6IPT4 1 54169651-54200036 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042671, HPA060463" Approved Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA042671: AB_2678107, HPA060463: AB_2684286" "unprognostic (2.03e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-2)" "unprognostic (1.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-3)" "unprognostic (1.90e-4)" "unprognostic (6.45e-3)" "unprognostic (9.75e-2)" "unprognostic (2.04e-1)" "unprognostic (5.93e-2)" "unprognostic (2.58e-1)" "unprognostic (2.35e-1)" "unprognostic (1.80e-2)" "unprognostic (5.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.86e-1)" 2.1 4.4 1.6 1.4 1.8 2.3 2.5 1.7 2.0 2.4 2.7 2.5 2.7 2.7 2.5 2.3 2.8 2.2 3.4 1.7 1.2 2.5 2.9 1.8 2.6 1.4 1.4 4.4 4.2 2.9 3.7 1.6 1.4 2.4 2.8 2.7 3.7 1.7 4.1 3.8 2.1 2.5 1.2 3.1 3.1 1.4 1.5 1.7 3.1 4.1 2.6 2.0 1.9 1.8 3.6 4.7 6.3 6.6 5.0 4.8 2.2 2.8 4.0 5.3 5.7 4.4 3.9 6.0 3.2 1.9 12.1 3.3 10.1 2.9 6.0 6.8 4.1 6.8 8.0 4.7 3.8 5.8 3.4 2.6 3.8 6.3 2.8 3.7 4.7 5.3 7.5 2.8 3.9 4.3 5.9 3.2 6.4 4.1 3.7 9.3 7.8 5.6 2.4 4.0 9.3 4.6 1.9 6.3 5.7 5.1 4.4 4.4 2.1 4.0 3.3 6.0 5.0 4.3 7.1 8.5 4.5 12.2 6.3 0.7 0.4 0.4 0.2 0.9 0.1 0.2 0.3 0.1 0.4 0.3 0.2 0.2 0.5 0.8 0.2 0.4 0.1 0.3 1.6 1.8 1.7 2.0 1.7 1.2 1.4 1.4 1.4 1.2 1.5 1.8 1.6 0.0 7.2 1.3 1.3 0.1 1.1 0.9 0.0 4.0 2.3 2.4 5.1 2.8 3.0 3.7 4.2 1.9 0.4 1.1 7.9 3.0 0.1 3.6 2.0 6.1 2.4 6.1 2.4 4.2 2.3 2.4 1.1 2.1 2.5 4.8 3.9 2.9 5.3 0.0 2.2 1.2 4.1 1.6 0.4 1.0 1.5 1.2 0.0 2.8 1.2 1.9 4.1 2.5 3.1 1.4 0.8 1.9 2.0 0.8 1.4 2.7 5.9 4.0 0.0 2.6 1.4 1.2 5.1 0.8 0.9 0.3 1.6 2.9 2.3 0.9 CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 1125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" 84.7 173.2 92.1 62.4 97.2 104.4 72.7 115.4 103.8 71.4 102.4 162.6 171.2 75.9 35.7 155.5 67.8 39.5 527.7 92.3 105.3 152.6 180.4 56.7 55.8 99.8 96.9 63.6 101.2 163.3 58.2 45.8 103.1 67.8 111.0 42.0 104.4 70.0 730.0 106.5 127.5 59.9 94.9 70.1 139.6 38.9 106.9 63.4 64.8 724.9 61.0 92.0 86.5 99.6 172.0 381.4 98.9 208.4 80.5 88.5 189.6 96.7 116.7 240.2 156.9 269.4 208.2 241.0 210.8 129.8 116.2 247.3 217.9 191.2 89.8 148.2 289.2 259.7 306.5 250.4 143.1 154.7 162.5 129.4 234.9 153.2 301.4 80.6 141.3 163.7 240.4 208.2 127.7 616.8 292.0 143.5 115.1 476.8 1125.5 253.7 132.4 422.1 199.7 273.0 263.3 117.2 267.8 365.7 200.0 54.0 302.5 233.2 108.8 152.1 321.6 169.6 299.7 229.1 179.7 183.8 193.2 261.9 198.4 185.7 340.4 95.7 131.6 360.4 139.8 208.7 108.1 141.5 444.1 180.3 104.9 134.6 32.7 187.8 278.8 251.0 158.2 397.1 92.1 97.2 115.4 103.8 92.3 105.3 99.8 96.9 103.1 94.9 106.9 99.6 77.0 19.2 29.3 23.5 94.0 156.1 191.9 394.8 62.6 113.6 110.7 102.6 402.3 181.6 156.0 79.1 81.3 263.6 61.7 516.1 817.8 239.9 81.2 59.1 68.1 88.0 146.4 130.6 14.4 289.1 257.1 102.8 144.8 60.2 59.7 89.2 62.4 239.4 246.3 87.5 21.6 390.4 272.6 104.8 139.4 88.6 88.9 101.4 179.7 12.2 208.4 115.2 92.7 12.1 17.5 290.6 332.5 90.7 149.9 237.9 570.0 468.6 86.1 100.9 72.3 109.4 250.6 83.1 116.7 212.9 163.7 236.8 63.8 197.5 602.6 258.3 CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" 86.0 115.6 65.8 89.2 70.4 85.0 59.2 79.8 101.7 45.3 87.6 263.6 150.1 42.3 41.5 105.9 43.0 52.9 476.8 72.1 82.8 174.6 115.7 54.3 63.8 71.0 72.9 48.1 38.5 226.2 57.0 43.0 69.4 54.3 238.8 153.9 58.0 60.1 483.7 47.6 120.1 91.1 70.2 48.0 108.1 61.1 83.4 74.0 74.6 799.8 89.4 119.8 60.1 71.7 336.4 185.1 195.0 273.7 108.7 83.1 199.6 314.4 128.0 229.2 264.5 307.4 222.2 383.8 152.9 138.5 678.3 385.8 396.5 295.0 401.2 115.0 179.1 318.6 208.9 218.7 170.2 739.0 271.1 111.2 257.5 230.9 492.9 99.4 209.5 232.2 597.1 397.9 246.0 155.1 408.6 284.4 365.1 746.3 343.0 282.1 235.3 364.5 360.9 322.5 392.6 190.3 164.5 689.0 267.9 338.7 359.5 436.6 152.8 209.3 383.3 329.8 591.8 401.4 507.3 860.5 281.0 526.4 606.7 65.3 56.2 42.8 68.0 106.0 82.5 102.5 62.2 71.6 105.7 90.0 58.6 70.2 8.2 73.3 96.8 81.5 87.5 83.0 65.8 70.4 79.8 101.7 72.1 82.8 71.0 72.9 69.4 70.2 83.4 71.7 244.3 83.3 118.6 42.4 337.6 689.8 818.3 698.5 237.9 163.1 210.6 179.6 770.0 144.4 314.2 183.9 77.2 192.6 304.4 827.5 1663.0 278.3 496.4 154.8 120.2 183.3 384.9 162.6 53.2 216.0 351.0 257.3 287.5 197.5 212.6 68.7 81.0 210.8 353.0 132.9 64.6 522.5 502.5 141.5 715.2 161.8 90.1 329.2 590.5 16.9 245.8 220.9 197.8 17.1 24.2 303.8 570.5 93.6 358.7 551.9 392.8 638.6 146.1 195.2 138.1 294.7 962.3 423.1 211.1 402.7 715.2 349.3 349.7 146.9 600.2 884.1 CYREN "C7orf49, FLJ22450, FLJ27285, MGC5242, MRI, MRI-2" ENSG00000122783 "Cell cycle regulator of NHEJ" Q9BWK5 7 135092363-135170795 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 69.1;Distal tubular cells: 72.4;Ductal cells: 51.0;Extravillous trophoblasts: 65.6;Hofbauer cells: 41.3;Proximal tubular cells: 47.3;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020060 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA020060: AB_2290651" "unprognostic (3.32e-1)" "unprognostic (1.78e-2)" "unprognostic (1.20e-1)" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (2.52e-5)" "unprognostic (8.89e-3)" "unprognostic (2.92e-2)" "unprognostic (3.21e-3)" "unprognostic (8.39e-2)" "unprognostic (3.09e-1)" "unprognostic (1.59e-1)" "unprognostic (1.60e-1)" "unprognostic (8.65e-2)" "unprognostic (3.96e-1)" "unprognostic (2.69e-1)" 16.2 20.1 11.8 15.4 15.7 16.5 16.2 15.0 13.1 16.4 18.9 14.5 13.7 18.5 16.6 18.6 21.1 11.6 15.9 11.5 13.1 30.1 14.1 13.9 19.3 18.7 14.6 18.3 21.0 26.2 16.3 20.6 17.4 15.4 13.9 6.6 22.5 22.8 33.4 13.6 13.6 18.1 13.8 17.2 18.5 13.9 14.6 19.5 15.0 18.9 23.7 16.6 14.8 18.9 59.9 62.7 29.4 46.0 24.9 23.7 49.1 38.3 38.8 49.0 38.1 40.1 42.0 48.3 42.2 39.2 52.1 32.8 42.2 69.6 31.6 62.1 27.1 32.0 34.2 37.2 35.4 64.0 37.4 27.6 68.4 38.3 44.0 22.5 21.2 37.4 117.5 31.9 40.3 60.4 60.6 44.0 67.8 50.5 46.1 44.1 36.4 64.1 57.1 35.4 34.7 53.4 43.4 37.7 42.5 32.1 30.0 57.4 18.4 43.8 24.6 39.0 66.3 56.8 69.8 65.8 60.7 62.5 90.9 32.2 27.5 27.9 12.3 24.5 13.4 18.3 10.8 16.7 30.3 19.4 15.8 15.9 6.1 27.2 24.1 25.8 5.4 20.9 11.8 15.7 15.0 13.1 11.5 13.1 18.7 14.6 17.4 13.8 14.6 18.9 12.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 15.2 13.8 0.0 0.0 0.0 31.3 0.0 69.1 9.9 0.0 72.4 51.0 0.0 11.8 13.4 6.3 0.0 0.0 0.0 35.4 65.6 8.0 0.0 25.6 0.0 17.0 0.0 0.0 41.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 32.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 2.2 0.0 0.0 47.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 46.7 4.3 17.8 0.0 0.0 DAP3 "bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29" ENSG00000132676 "Death associated protein 3" P51398 1 155687960-155739010 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Apoptosis "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023687 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA023687: AB_1847472" "unprognostic (2.60e-1)" "unprognostic (2.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.80e-1)" "unprognostic (5.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.87e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (4.14e-6)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" 57.0 63.6 32.5 54.7 34.9 66.7 66.2 33.6 38.8 43.3 32.5 55.7 58.7 46.0 52.3 54.5 41.9 38.6 88.1 36.1 37.5 63.1 88.2 44.6 69.3 36.1 35.8 38.1 69.3 49.4 42.4 41.2 38.9 50.7 61.4 71.9 53.3 49.4 129.9 60.1 47.6 53.2 32.1 51.3 59.1 42.3 37.1 80.8 48.9 89.4 78.6 58.4 45.3 41.6 144.9 91.9 73.5 116.7 105.9 133.0 180.0 118.8 124.8 119.4 103.8 170.7 172.4 204.1 235.0 97.3 76.5 143.1 110.3 103.7 129.8 128.6 80.4 124.7 80.5 156.5 144.5 173.3 106.4 112.1 145.8 152.2 199.4 93.3 119.2 185.2 274.5 141.2 125.6 192.0 152.6 200.9 130.1 225.2 146.9 124.2 92.1 218.9 142.5 136.0 84.9 150.4 113.9 331.9 211.6 135.1 206.4 279.8 102.8 100.5 106.1 126.0 202.6 152.9 245.9 235.3 100.2 151.6 132.7 65.4 110.5 61.6 110.1 134.2 179.0 141.5 155.8 133.9 152.0 121.1 192.5 167.5 47.8 136.0 128.0 99.1 173.1 162.1 32.5 34.9 33.6 38.8 36.1 37.5 36.1 35.8 38.9 32.1 37.1 41.6 31.8 44.8 43.6 34.0 59.2 54.9 67.2 94.2 52.9 28.2 54.6 43.8 106.2 51.5 68.3 16.5 20.9 76.2 45.0 33.2 66.5 79.8 19.0 44.9 40.5 38.1 25.7 63.8 52.7 78.6 98.5 41.3 35.7 38.7 62.1 34.9 33.2 57.4 77.8 13.5 57.4 41.9 59.0 59.4 62.9 15.3 32.3 53.0 35.6 30.9 83.7 22.2 55.6 26.7 47.1 73.8 30.8 25.2 52.4 81.7 41.7 78.0 61.2 46.4 13.1 33.7 45.1 48.3 29.3 51.1 63.1 141.6 66.4 73.3 62.5 73.5 DARS1 DARS ENSG00000115866 "Aspartyl-tRNA synthetase 1" P14868 2 135905881-135986100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 85.1;Cytotrophoblasts: 115.4;Extravillous trophoblasts: 157.9;Hofbauer cells: 94.2;Syncytiotrophoblasts: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 37.5 42.1 30.1 41.2 31.2 34.0 48.7 33.3 52.1 34.7 28.0 38.5 23.5 38.4 22.8 46.0 37.8 25.8 42.3 29.5 35.2 47.3 44.2 27.8 48.3 32.6 31.2 47.2 36.1 38.4 24.6 44.4 35.6 33.6 26.6 87.1 32.5 36.5 82.8 40.2 28.0 39.3 34.0 32.3 33.3 17.8 30.7 63.1 43.4 60.1 55.4 40.0 36.4 35.3 201.6 77.0 73.4 66.3 61.0 78.1 141.6 99.8 92.6 92.2 91.1 163.0 84.0 210.0 159.8 78.4 86.6 111.7 94.9 114.9 170.3 95.6 86.0 134.0 76.8 185.6 83.9 188.3 90.8 84.5 75.6 109.1 99.8 122.9 46.8 106.3 131.6 66.0 66.6 87.3 139.2 117.4 77.8 85.3 66.9 179.3 157.9 139.0 91.8 76.9 40.3 89.6 75.0 63.5 74.8 72.2 66.8 118.2 38.2 86.0 87.4 64.5 92.8 194.9 123.3 250.2 144.1 132.3 51.0 33.7 85.4 51.2 115.2 82.6 174.7 219.9 172.6 151.4 133.7 198.8 175.2 154.2 31.7 171.9 67.4 130.4 168.9 153.3 30.1 31.2 33.3 52.1 29.5 35.2 32.6 31.2 35.6 34.0 30.7 35.3 29.4 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 115.4 20.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 157.9 18.2 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 136.4 4.4 0.0 0.0 0.0 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423615-30430030 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Supported Nucleoplasm,Cytosol NA Yes 61000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavorable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 21.0 21.4 17.6 27.4 18.4 22.2 30.5 18.7 22.5 18.6 18.9 56.4 32.0 18.6 20.0 28.3 28.1 19.5 31.1 18.4 19.5 39.7 21.8 16.2 35.5 18.1 17.6 14.0 24.9 32.1 10.3 16.0 19.0 21.8 58.4 12.2 25.5 19.3 44.7 25.1 27.7 20.5 18.4 27.8 24.3 9.1 18.1 24.5 20.1 36.9 35.7 27.0 19.1 19.4 124.7 149.8 66.8 85.8 18.4 24.1 61.9 58.4 35.1 87.4 87.9 114.7 103.4 168.1 119.1 36.8 54.9 95.9 141.4 115.1 103.5 89.2 221.0 98.3 61.5 150.3 24.1 177.0 144.2 28.6 64.8 96.4 55.6 25.4 88.7 88.2 125.8 57.4 61.5 217.8 210.0 189.9 88.8 124.2 119.2 293.1 74.8 218.1 98.9 80.2 141.4 80.4 39.0 137.7 55.3 41.5 118.4 73.9 45.9 66.0 59.1 85.8 107.2 36.9 118.4 217.5 43.8 145.7 79.6 70.6 36.7 38.1 54.0 70.0 75.8 146.7 68.4 61.4 86.7 128.7 60.9 59.0 4.6 76.1 79.2 94.6 76.4 81.0 17.6 18.4 18.7 22.5 18.4 19.5 18.1 17.6 19.0 18.4 18.1 19.4 34.0 19.2 15.2 0.7 38.2 90.2 53.3 92.5 33.6 23.3 45.8 48.9 34.8 51.5 37.9 44.1 8.4 103.2 22.7 130.3 127.2 135.6 13.4 32.6 29.9 47.4 38.5 29.6 2.6 124.8 101.0 28.3 27.5 66.5 31.1 40.2 31.1 23.2 76.9 15.2 2.7 142.3 73.2 21.0 49.1 45.1 19.6 26.9 48.0 1.0 73.2 25.0 23.7 2.5 4.4 89.0 115.8 19.9 24.1 86.9 68.8 76.7 27.8 21.4 19.7 23.7 40.0 3.3 44.8 39.4 80.3 27.8 28.3 53.8 168.5 45.7 DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15634346 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Supported Nucleoplasm,Cytosol NA NA 86000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "CAB012280: , HPA034502: AB_10794321, HPA034503: AB_10795025" "unprognostic (9.94e-2)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (8.36e-3)" "unprognostic (9.28e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (2.55e-1)" "unprognostic (2.05e-1)" "unprognostic (4.81e-3)" "unprognostic (3.89e-2)" "unprognostic (2.03e-1)" "prognostic favorable (9.69e-4)" "unprognostic (3.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.94e-2)" "unprognostic (1.20e-3)" 52.8 53.4 32.6 39.0 33.5 37.8 61.7 36.1 44.2 49.9 39.6 54.3 45.0 45.4 48.0 56.5 42.4 31.7 97.6 33.8 37.1 76.7 62.0 38.9 35.3 36.8 32.6 45.7 59.0 89.5 46.7 50.9 36.0 44.6 58.0 55.5 52.9 47.8 157.9 50.3 46.0 56.5 34.7 33.8 50.5 42.5 35.3 47.0 62.3 134.2 46.8 48.4 41.0 36.3 84.1 127.1 172.3 126.2 148.1 125.5 193.3 176.8 142.6 165.1 135.9 203.0 80.7 221.8 80.4 202.8 120.9 118.8 245.5 166.8 170.7 94.6 154.3 244.5 150.6 241.8 110.2 204.5 102.3 101.2 105.9 140.6 129.6 100.8 151.0 98.4 253.4 61.8 161.9 112.2 110.3 126.7 221.0 205.6 104.4 125.0 276.8 152.6 178.9 161.9 136.6 169.3 124.3 118.0 154.8 123.2 83.6 77.5 133.7 132.1 139.8 84.2 197.2 84.5 169.3 296.2 120.5 153.7 128.4 32.4 34.5 20.3 31.0 42.0 33.2 28.6 35.8 37.0 38.8 30.5 39.9 35.8 3.0 38.5 42.0 30.1 38.1 34.1 32.6 33.5 36.1 44.2 33.8 37.1 36.8 32.6 36.0 34.7 35.3 36.3 41.3 80.1 57.6 25.8 34.9 40.3 57.2 96.4 31.9 58.9 50.3 41.5 362.7 67.2 78.6 90.1 52.1 112.1 29.0 43.7 142.8 112.3 23.1 49.2 69.6 57.2 52.1 64.2 52.1 120.3 108.5 67.0 28.5 51.2 57.0 49.3 47.5 123.0 53.4 45.4 48.6 69.8 83.4 30.3 19.7 19.5 72.7 28.1 49.8 29.0 41.2 60.1 55.6 45.8 49.0 107.2 52.4 78.2 32.8 31.3 74.5 170.2 80.6 75.9 59.2 51.3 94.6 174.0 76.8 30.0 42.3 80.2 30.7 73.5 74.1 36.6 DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.3;Inhibitory neurons: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nuclear speckles" "HPA042586: AB_2678064" "unprognostic (8.79e-2)" "unprognostic (1.58e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (7.79e-3)" "unprognostic (3.99e-2)" "unprognostic (3.13e-2)" "unprognostic (5.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" 2.0 2.7 2.4 3.8 8.3 5.6 5.7 3.9 3.0 3.1 1.5 6.0 5.7 2.1 4.0 4.4 2.0 3.4 5.8 2.1 4.4 5.6 5.0 4.3 6.5 2.9 5.3 4.0 5.8 5.9 2.5 1.5 3.6 3.8 5.7 5.9 4.5 3.2 3.9 1.9 6.9 1.9 1.9 4.3 4.8 2.2 4.5 6.6 6.0 5.9 6.5 4.0 2.8 2.6 7.2 1.8 2.0 3.4 0.9 5.0 3.0 5.4 3.7 3.3 2.0 1.9 4.5 13.0 2.7 8.3 1.9 3.6 3.2 3.9 2.9 10.0 3.4 4.7 3.7 0.9 2.7 15.5 5.6 1.7 5.2 1.3 3.6 10.0 1.4 7.4 3.6 19.6 3.3 1.3 8.3 7.9 0.7 1.8 1.7 5.1 1.7 10.3 7.9 6.6 3.4 5.3 8.3 5.5 1.5 3.1 2.3 13.4 4.0 0.4 3.1 0.2 3.2 9.8 0.0 6.4 3.4 6.2 6.2 2.3 0.1 1.1 0.9 0.3 0.4 1.2 0.6 1.4 0.7 0.3 0.3 0.6 0.4 2.7 0.3 0.9 1.8 0.3 2.4 8.3 3.9 3.0 2.1 4.4 2.9 5.3 3.6 1.9 4.5 2.6 9.1 41.7 16.2 46.4 24.1 8.4 23.6 9.2 12.0 18.3 28.9 11.9 28.3 15.7 17.3 14.7 25.0 10.4 22.1 65.5 17.6 9.7 26.8 7.9 5.7 6.5 14.4 8.0 101.3 23.1 9.7 10.9 20.9 17.1 64.7 12.8 9.3 15.3 18.9 5.0 138.5 27.4 4.1 18.9 82.4 26.8 23.9 30.0 16.0 42.2 15.8 8.6 28.8 75.4 5.8 22.5 54.5 13.2 50.7 21.9 59.9 16.4 9.6 14.0 0.0 13.9 6.3 8.1 13.9 22.9 12.1 7.4 42.5 5.7 27.9 53.5 DENR "DRP, DRP1, SMAP-3" ENSG00000139726 "Density regulated re-initiation and release factor" O43583 12 122752824-122771064 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 227.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021783 Approved Approved Cytosol NA NA 200000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA021783: AB_2670820" "unprognostic (3.65e-2)" "unprognostic (7.00e-2)" "unprognostic (5.69e-2)" "unprognostic (7.33e-3)" "unprognostic (6.62e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (2.23e-3)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (3.75e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (8.57e-6)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" 25.4 22.6 19.0 27.0 19.6 27.5 29.6 15.3 23.6 22.2 15.1 25.5 26.7 23.7 22.1 32.5 21.7 22.1 24.4 19.4 20.2 25.5 27.6 18.8 36.2 16.8 21.6 19.2 21.2 59.0 17.1 31.6 19.5 28.0 26.0 16.5 28.4 24.8 60.2 29.6 25.0 24.5 15.2 28.0 23.3 14.6 18.9 38.9 29.8 44.7 35.5 30.0 20.4 16.7 113.1 62.1 77.7 80.1 48.7 71.9 67.6 100.5 56.1 87.6 60.6 86.9 40.6 99.9 103.4 72.5 66.6 84.0 93.8 89.5 117.6 90.9 67.3 122.8 36.2 63.8 63.5 139.6 97.4 62.8 86.9 79.3 107.4 81.6 86.4 109.7 129.8 35.8 94.8 74.9 137.7 134.1 159.2 67.2 128.4 120.6 91.2 63.7 85.3 99.9 89.3 63.4 139.2 40.8 107.3 79.1 129.5 78.1 82.2 81.2 95.9 91.7 102.1 58.8 145.8 160.4 76.4 100.1 90.9 227.9 35.0 58.1 38.8 53.3 45.3 45.5 41.9 39.4 47.3 41.4 48.5 43.4 42.2 47.3 69.9 42.1 49.2 44.5 19.0 19.6 15.3 23.6 19.4 20.2 16.8 21.6 19.5 15.2 18.9 16.7 43.4 70.5 40.1 31.0 59.8 71.9 65.9 55.4 59.7 37.7 66.2 69.8 66.3 45.8 47.7 47.8 41.7 73.0 60.8 40.9 64.6 68.6 17.9 67.7 83.5 51.4 84.8 53.8 39.0 61.8 130.3 48.3 40.8 70.7 43.1 50.4 42.1 54.3 57.4 55.5 36.2 53.6 44.7 50.1 42.4 8.0 50.4 49.3 26.6 25.3 60.2 47.3 75.2 48.2 31.3 88.0 44.6 45.9 47.9 73.2 40.3 67.3 49.5 35.9 19.7 46.2 62.5 120.3 136.8 72.8 64.9 60.6 54.7 47.3 58.8 51.3 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 10.6 10.6 5.3 9.7 5.7 6.7 12.0 9.1 7.0 12.5 6.7 12.1 7.2 11.4 6.8 12.7 9.5 8.9 10.7 5.7 5.1 16.9 13.1 9.4 9.5 5.0 5.0 8.9 11.7 18.7 10.4 11.4 5.1 13.4 9.8 8.7 10.3 12.0 24.2 11.6 8.4 12.6 5.5 7.9 10.4 7.4 5.1 10.0 15.4 14.8 9.7 12.0 10.3 7.1 36.7 25.5 20.9 27.2 32.3 28.2 25.6 38.9 30.9 28.2 28.7 21.3 23.0 20.7 34.9 44.5 35.8 26.0 34.0 37.1 40.5 9.1 19.4 18.8 21.6 14.6 18.3 13.3 19.6 23.8 23.0 29.9 17.2 18.5 37.9 16.5 24.4 15.0 33.4 25.9 21.4 11.1 17.5 10.5 27.1 10.9 31.8 35.7 23.0 25.3 19.6 12.5 37.4 21.3 18.6 20.5 28.7 21.7 32.9 25.9 20.2 22.8 27.4 13.2 24.1 29.0 29.9 23.0 29.1 68.6 22.5 24.3 18.0 24.4 20.4 27.3 22.5 20.0 17.5 26.3 25.0 21.6 20.6 24.5 30.1 36.8 21.9 8.9 5.3 5.7 9.1 7.0 5.7 5.1 5.0 5.0 5.1 5.5 5.1 7.1 44.5 70.5 42.6 34.0 35.2 37.6 37.5 71.8 39.3 81.6 44.9 49.8 73.6 41.5 69.4 64.4 41.7 68.3 39.5 34.4 54.8 61.4 54.8 37.4 61.5 40.7 38.4 68.4 47.3 61.7 54.6 52.7 35.7 36.5 31.6 39.0 22.9 45.0 41.2 42.1 46.9 36.4 63.1 26.0 26.6 16.6 46.6 41.5 28.4 28.1 50.7 35.7 35.0 42.7 54.9 61.9 27.3 53.0 57.0 53.2 35.2 105.2 35.9 83.6 52.6 52.8 54.2 117.5 108.1 50.1 47.5 81.3 36.1 106.4 39.9 43.3 DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 89.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.5;Distal tubular cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Supported Mitochondria NA NA 44000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favorable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favorable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 24.7 16.5 7.7 13.3 8.3 7.9 14.5 9.5 9.3 11.0 10.4 24.7 18.3 10.0 13.4 19.5 13.0 8.5 69.4 8.1 11.1 33.8 15.5 11.7 16.1 8.3 8.9 9.5 6.8 31.7 8.5 13.1 9.7 14.5 26.0 10.8 16.8 14.8 75.4 10.3 16.5 13.4 8.2 9.9 14.3 9.9 9.4 12.7 20.2 89.4 18.2 14.2 8.1 8.0 18.7 16.4 28.2 34.4 41.6 30.5 26.5 26.6 18.2 34.8 38.7 52.8 56.7 85.4 46.0 28.7 42.6 41.0 65.7 34.2 38.9 27.3 30.2 51.9 17.9 39.2 29.0 64.9 26.6 36.9 37.7 32.0 35.2 24.2 33.9 41.7 88.4 42.6 41.2 16.6 25.4 66.9 30.3 58.6 35.4 45.4 38.0 93.3 64.4 21.4 51.2 27.8 30.7 93.4 20.5 30.9 67.4 42.9 17.8 29.1 29.1 29.1 33.0 11.1 19.4 127.5 7.7 73.0 22.7 9.1 3.8 3.0 4.3 5.8 5.4 5.6 4.9 5.1 5.8 4.0 5.6 5.1 0.3 4.7 6.1 4.5 5.8 5.0 7.7 8.3 9.5 9.3 8.1 11.1 8.3 8.9 9.7 8.2 9.4 8.0 7.6 12.8 14.5 15.3 13.8 11.2 9.2 18.2 14.2 8.1 9.2 5.8 100.5 15.7 13.2 11.0 0.0 21.2 6.4 26.3 74.3 18.7 3.9 15.8 11.6 9.6 17.3 18.1 18.0 11.4 39.6 11.7 11.7 12.1 3.8 13.5 7.5 15.5 18.7 8.4 24.4 17.8 24.4 8.8 7.5 3.2 6.2 9.5 17.8 9.4 16.7 10.4 4.1 11.1 19.7 14.1 9.2 10.9 19.4 7.0 19.0 37.6 30.3 11.1 0.0 14.2 19.9 25.1 18.3 21.1 9.8 17.4 8.5 26.3 26.7 9.3 DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.2;Distal tubular cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 108.7 98.9 22.7 42.1 23.7 54.0 49.0 27.1 29.1 36.3 35.6 109.0 81.8 45.3 21.2 94.1 34.3 48.5 264.1 23.1 29.5 153.3 112.8 39.3 50.1 27.1 27.4 30.0 49.2 136.7 27.8 43.1 26.6 45.7 99.3 35.0 50.2 50.3 295.0 38.9 71.9 67.7 24.9 38.4 80.5 31.3 25.7 43.2 64.2 357.0 67.5 66.1 32.7 23.4 171.4 134.5 74.8 127.9 104.6 91.4 88.4 96.5 80.8 110.6 86.2 159.5 95.5 165.9 159.6 103.0 177.7 110.9 150.2 135.8 166.1 111.1 88.4 116.9 175.6 116.7 80.3 194.7 116.0 104.8 97.6 116.4 63.4 72.3 134.0 137.0 298.5 119.7 121.8 188.1 161.8 138.9 87.4 206.0 98.2 113.1 117.8 225.9 151.8 250.8 92.3 99.9 156.3 262.1 143.9 149.9 100.5 165.8 87.9 120.7 97.3 238.1 149.4 89.3 187.1 114.6 115.0 204.1 130.2 132.7 63.9 136.0 46.9 81.6 49.4 37.8 46.8 46.8 87.2 38.5 47.9 50.5 39.9 68.1 116.9 29.9 49.0 64.2 22.7 23.7 27.1 29.1 23.1 29.5 27.1 27.4 26.6 24.9 25.7 23.4 26.7 28.9 20.7 14.7 26.3 31.4 42.7 124.7 31.3 47.1 24.0 19.2 356.2 51.5 70.5 79.1 22.9 110.2 27.3 56.1 226.9 69.3 10.2 27.6 26.2 32.2 30.6 53.9 23.9 55.9 62.7 36.3 36.7 28.0 26.6 35.3 26.0 86.8 69.2 21.9 25.3 44.1 114.0 41.0 26.5 7.3 23.3 37.5 37.4 15.9 62.2 36.0 38.1 21.1 16.7 42.6 51.4 42.2 30.7 24.3 60.0 178.9 55.5 45.5 26.3 28.4 44.8 55.2 51.5 48.0 32.4 108.4 29.5 73.7 78.7 39.2 DLST "DLTS, KGD2, OGDC-E2" ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903743 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 70000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Mitochondria, Cytosol" "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 64.5 85.5 33.5 32.3 34.7 75.0 59.6 35.8 34.7 62.1 43.8 63.3 58.7 47.5 43.2 62.9 46.1 36.2 129.0 30.8 35.1 100.4 78.4 48.5 36.9 35.8 34.5 45.8 44.8 78.8 35.4 44.8 34.3 41.3 59.3 37.1 46.5 43.5 144.7 64.3 58.3 52.1 33.6 46.1 57.7 29.3 37.3 42.5 42.9 224.2 45.7 58.0 49.7 32.5 79.1 81.1 63.7 45.4 98.1 110.6 97.5 106.3 107.8 106.8 99.0 80.9 88.1 81.0 44.3 118.1 48.1 87.8 109.0 105.6 112.0 61.5 43.3 68.4 66.3 74.8 101.4 49.5 45.4 114.0 90.5 103.8 126.7 95.5 106.1 36.6 53.4 55.6 110.3 112.0 59.0 69.7 55.0 146.6 79.0 73.8 93.8 46.7 125.8 100.8 75.5 64.1 100.6 129.4 71.3 54.2 121.7 70.5 90.8 63.8 83.2 79.5 74.0 38.7 43.7 73.4 93.9 47.9 68.8 3.0 1.3 2.3 2.1 2.0 1.8 1.6 1.9 1.6 2.1 1.0 1.5 2.2 1.3 3.5 1.8 2.8 2.0 1.5 33.5 34.7 35.8 34.7 30.8 35.1 35.8 34.5 34.3 33.6 37.3 32.5 24.2 6.4 4.8 14.0 22.7 26.4 23.5 19.7 21.6 19.1 25.1 20.4 28.5 21.5 10.1 20.2 31.3 41.0 27.7 41.9 56.7 37.8 7.3 10.9 20.4 19.8 14.8 22.5 21.9 25.7 38.8 25.6 30.5 18.9 21.0 19.4 23.2 43.6 32.1 13.5 24.6 31.8 12.2 20.9 19.0 6.2 18.0 18.8 23.2 13.1 27.1 10.0 20.6 18.6 18.5 44.3 28.0 20.7 20.0 28.2 49.8 73.3 8.7 20.8 26.3 18.3 24.0 12.1 15.3 34.2 28.4 79.5 23.1 19.3 40.5 27.7 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.2;lymphoid tissue: 20.9;parathyroid gland: 46.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 115.4;Ionocytes: 46.8;Skeletal myocytes: 22.7" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.8;RH-30: 5.0;RPMI-8226: 19.4;SK-MEL-30: 5.2;THP-1: 3.6;WM-115: 3.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" 4.7 0.1 1.7 0.1 3.4 0.0 5.3 3.1 2.7 0.1 0.2 1.6 0.0 0.1 1.1 0.3 0.6 0.0 0.1 1.9 1.9 41.2 0.0 3.1 0.2 3.0 3.1 0.0 0.0 46.4 0.5 0.2 2.9 0.3 0.9 0.4 1.3 1.4 13.3 0.3 0.1 0.0 1.7 0.0 0.0 0.8 2.8 20.9 0.1 2.5 0.1 0.0 0.2 8.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.0 19.4 0.0 0.8 2.9 0.0 0.0 0.0 5.2 0.3 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 3.1 2.7 1.9 1.9 3.0 3.1 2.9 1.7 2.8 8.5 0.5 0.0 0.0 0.3 0.2 0.5 0.6 1.8 0.0 0.1 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.1 0.1 1.8 115.4 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.0 46.8 0.0 1.1 0.4 0.6 0.2 3.6 0.0 0.0 0.3 0.0 0.5 11.1 0.0 1.9 0.0 0.4 0.2 0.0 0.4 0.6 2.4 0.0 22.7 0.7 4.0 3.0 0.2 0.1 0.1 0.1 0.0 1.8 0.4 DNAJC11 FLJ10737 ENSG00000007923 "DnaJ heat shock protein family (Hsp40) member C11" Q9NVH1 1 6634168-6701924 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023707, HPA028705" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA023707: , HPA028705: AB_10603662" "unprognostic (3.74e-2)" "unprognostic (3.19e-2)" "unprognostic (4.06e-2)" "unprognostic (6.05e-3)" "unprognostic (9.55e-2)" "unprognostic (6.65e-2)" "unprognostic (4.38e-3)" "unprognostic (6.10e-2)" "unprognostic (6.34e-2)" "unprognostic (2.89e-1)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.30e-2)" "unprognostic (1.76e-1)" "unprognostic (9.77e-2)" "unprognostic (1.04e-1)" 16.9 28.3 15.8 19.1 16.3 14.5 16.3 14.5 20.0 15.2 11.9 28.6 27.2 17.2 12.7 24.2 15.5 12.5 37.2 17.7 15.1 54.5 28.8 13.6 19.0 17.9 16.5 18.7 19.0 24.5 12.7 17.7 18.1 15.4 31.7 16.5 17.1 13.8 44.0 20.3 23.3 17.6 13.5 23.3 21.7 16.5 17.8 15.4 14.6 35.9 18.5 18.6 16.2 17.7 44.5 41.5 47.6 44.3 40.5 28.6 44.7 42.6 36.5 82.7 58.9 51.2 61.7 70.0 41.2 49.2 35.3 58.1 82.9 69.1 72.1 40.0 57.6 71.0 84.1 51.4 40.7 85.4 37.6 42.3 19.0 74.8 48.7 29.2 39.6 52.2 92.6 29.7 42.3 35.5 53.6 45.1 49.9 60.2 71.9 60.0 41.7 50.9 53.0 37.3 64.9 46.0 49.3 98.2 55.4 39.9 39.1 44.6 40.5 48.9 26.1 40.9 51.7 34.5 40.7 91.2 48.1 93.5 25.0 10.2 9.6 3.4 8.7 12.8 8.8 7.5 6.2 9.4 12.1 8.4 6.6 5.2 0.3 10.0 14.4 5.3 7.6 9.2 15.8 16.3 14.5 20.0 17.7 15.1 17.9 16.5 18.1 13.5 17.8 17.7 11.9 9.6 11.8 17.3 9.7 19.6 4.4 9.1 4.6 18.5 8.6 9.8 9.7 2.8 9.7 12.9 29.2 21.4 5.3 33.4 35.2 14.2 14.9 8.6 13.1 9.3 14.6 25.2 28.6 13.7 22.8 10.3 23.0 10.5 5.1 27.4 5.0 14.1 16.7 20.2 35.8 22.9 14.2 8.2 24.2 9.3 8.1 9.6 28.4 18.7 8.4 11.8 6.2 15.6 23.3 11.1 19.6 4.5 13.3 6.5 37.2 32.4 12.0 17.7 6.6 11.8 13.7 17.0 11.6 14.5 18.3 23.8 8.9 24.9 36.4 5.3 DNAJC16 KIAA0962 ENSG00000116138 "DnaJ heat shock protein family (Hsp40) member C16" Q9Y2G8 1 15526813-15592379 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043643 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA043643: AB_10796794" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "prognostic favorable (6.77e-4)" "unprognostic (4.52e-2)" "unprognostic (5.51e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (4.28e-2)" "unprognostic (2.35e-2)" "unprognostic (3.74e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" "unprognostic (5.38e-2)" "unprognostic (4.70e-2)" 4.9 5.2 4.5 5.5 5.3 2.2 6.5 5.4 6.5 5.0 7.8 6.0 6.5 5.6 7.6 5.4 6.8 4.5 5.1 5.3 4.9 11.5 10.1 4.8 6.2 4.2 4.4 5.7 6.4 10.0 5.3 5.8 4.8 5.5 5.9 9.0 7.0 4.8 11.9 5.6 5.8 6.3 4.1 5.7 5.4 6.3 5.0 5.1 7.4 6.3 6.4 5.2 4.6 6.4 8.8 8.7 6.7 12.4 18.0 14.5 6.3 10.4 10.7 10.2 10.9 7.1 12.7 7.6 6.8 10.3 13.3 10.7 8.3 9.2 14.3 9.0 4.0 7.8 9.6 12.2 17.8 12.2 8.7 10.5 10.6 16.4 9.2 12.7 11.6 6.3 16.9 6.7 11.8 3.6 6.2 6.2 6.5 7.9 5.6 7.3 8.6 8.5 12.6 6.0 7.5 7.0 10.6 10.1 9.0 9.6 6.3 4.8 15.7 17.9 6.4 16.7 5.7 9.1 13.8 6.6 11.1 6.9 8.7 2.0 2.1 1.5 2.6 2.0 3.9 3.4 2.8 2.4 2.1 3.1 3.5 3.0 1.1 1.6 1.5 1.9 2.8 1.9 4.5 5.3 5.4 6.5 5.3 4.9 4.2 4.4 4.8 4.1 5.0 6.4 11.6 0.0 8.7 25.5 12.4 5.1 4.3 13.8 9.6 14.9 16.1 8.4 16.9 22.8 14.9 25.8 22.9 12.8 11.5 13.7 1.9 9.1 11.6 25.5 19.0 12.0 11.5 4.6 33.5 6.9 7.7 10.5 11.7 17.6 8.2 14.0 16.4 20.5 10.9 18.5 28.6 9.7 18.3 20.6 5.5 5.8 12.5 9.5 7.2 17.8 11.4 12.8 12.3 19.1 28.8 9.3 7.5 11.3 6.8 12.6 10.6 19.0 37.5 16.0 6.6 11.7 7.8 24.7 15.7 13.0 5.8 22.0 7.1 11.4 13.4 8.2 DPM1 "CDGIE, MPDS" ENSG00000000419 "Dolichyl-phosphate mannosyltransferase subunit 1, catalytic" O60762 20 50934867-50958555 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051818 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051818: AB_2681624" "unprognostic (2.21e-2)" "unprognostic (4.94e-2)" "unprognostic (1.16e-1)" "unprognostic (4.24e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.10e-1)" "unprognostic (7.49e-2)" "unprognostic (2.53e-2)" "unprognostic (1.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.02e-3)" "unprognostic (4.98e-2)" "unprognostic (2.59e-1)" "unprognostic (3.58e-1)" "unprognostic (2.74e-1)" 40.9 53.4 23.0 34.3 23.9 59.3 42.7 24.4 31.9 31.5 26.1 38.6 36.9 39.4 47.6 45.3 32.6 36.1 60.6 24.4 24.5 47.0 63.1 29.7 56.0 23.3 22.8 38.7 48.6 43.0 25.4 45.1 23.5 34.3 42.7 27.2 38.5 31.0 57.3 34.6 39.0 37.4 23.8 37.1 38.1 39.7 23.1 43.9 48.4 55.2 53.6 51.6 33.3 27.6 139.9 55.4 83.6 50.5 72.1 80.8 92.1 52.6 62.1 102.9 80.7 252.1 110.2 84.1 112.9 71.1 141.9 156.2 68.5 129.0 103.9 40.7 53.9 87.7 69.5 171.2 101.6 141.4 50.5 70.0 187.0 71.5 73.7 66.4 80.1 89.0 135.3 104.2 103.3 61.3 127.6 148.9 85.3 131.8 124.8 69.7 120.7 112.6 102.6 83.4 62.5 68.5 135.8 203.8 189.1 64.2 138.8 164.5 66.1 130.8 109.2 76.6 112.6 74.2 99.7 122.0 143.7 92.4 60.4 13.5 16.3 17.6 16.4 18.5 20.0 17.9 18.6 17.9 20.3 16.1 20.0 22.4 20.0 19.1 18.6 21.7 19.5 16.1 23.0 23.9 24.4 31.9 24.4 24.5 23.3 22.8 23.5 23.8 23.1 27.6 36.8 19.2 42.3 27.1 37.3 116.5 143.4 248.4 29.0 11.7 37.1 24.9 48.8 35.8 119.5 31.3 2.1 153.1 46.4 31.7 117.4 75.9 207.8 49.3 38.0 53.0 23.4 30.7 35.6 73.8 104.9 53.7 18.8 57.5 74.3 25.1 49.2 67.9 87.9 5.0 31.0 52.5 144.5 42.0 58.4 43.8 56.8 36.7 49.8 18.7 65.8 27.3 43.3 20.1 34.2 70.5 50.2 51.6 33.2 73.7 40.7 96.4 135.7 12.6 72.3 50.4 71.5 109.9 103.6 32.0 105.6 245.4 47.8 36.5 55.3 125.9 DTWD2 FLJ33977 ENSG00000169570 "DTW domain containing 2" Q8NBA8 5 118836074-118988547 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.4;Inhibitory neurons: 61.8;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053173, HPA054864" Approved Approved "Nuclear bodies" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" "HPA053173: AB_2682068, HPA054864: AB_2682629" "unprognostic (1.66e-1)" "unprognostic (1.60e-1)" "prognostic favorable (3.16e-4)" "unprognostic (4.80e-2)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (2.77e-3)" "unprognostic (5.15e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.09e-5)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (5.93e-3)" "unprognostic (1.59e-1)" 3.1 3.3 1.3 2.3 1.3 1.2 3.6 2.3 1.8 5.1 2.2 3.3 3.2 2.6 2.3 4.2 2.3 3.2 6.5 1.2 0.8 6.5 4.5 2.4 2.3 1.1 1.4 1.7 3.0 4.7 0.8 1.8 1.2 3.4 3.3 3.4 3.2 2.7 10.5 3.3 2.7 3.2 1.0 3.0 2.7 2.4 1.3 2.0 9.1 6.3 2.3 2.9 1.3 1.4 4.3 2.6 3.6 5.3 2.0 1.0 3.6 3.9 2.7 5.5 6.3 1.8 3.2 3.6 6.9 3.4 2.6 4.8 6.0 4.4 6.9 1.2 4.2 4.9 4.3 2.9 1.7 5.9 6.1 1.5 7.4 2.4 2.4 3.2 1.8 6.4 3.8 5.5 3.7 4.2 4.9 3.6 3.8 3.1 1.4 2.0 3.3 1.9 7.0 6.2 1.8 3.3 3.9 4.2 5.4 2.9 9.7 3.9 2.2 6.9 5.1 2.3 5.7 3.8 6.6 2.8 4.0 3.5 3.4 0.9 0.3 0.1 0.2 0.3 0.3 0.4 0.3 0.3 0.3 0.6 0.4 0.4 0.6 0.5 0.3 0.5 0.1 0.4 1.3 1.3 2.3 1.8 1.2 0.8 1.1 1.4 1.2 1.0 1.3 1.4 2.7 9.6 3.6 33.6 5.7 2.8 2.7 3.9 8.6 12.0 5.4 2.8 11.7 8.6 4.7 7.3 16.7 2.7 3.7 4.0 9.8 2.9 12.8 4.2 1.9 2.0 4.2 12.6 70.4 8.3 1.1 3.0 9.7 3.6 0.0 4.5 1.8 5.6 3.9 20.2 61.8 2.0 4.1 2.6 2.5 20.3 2.5 4.5 7.2 21.5 4.6 7.3 4.1 49.3 43.9 1.9 5.2 2.2 8.0 2.1 3.7 12.1 3.1 9.1 0.0 4.5 2.8 12.7 17.4 10.0 3.7 0.7 2.8 7.3 3.4 3.4 EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109565996 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" 23.3 28.4 18.6 17.6 19.9 16.9 32.4 23.4 26.3 36.1 19.8 28.6 23.5 22.8 44.7 17.0 27.6 19.4 24.7 19.1 20.5 37.0 45.2 28.1 25.4 18.9 19.0 22.2 36.7 34.9 20.5 18.1 19.0 23.3 31.2 32.5 42.9 27.6 53.2 17.9 21.0 17.0 19.1 20.7 27.2 25.3 19.3 20.6 57.4 42.3 27.0 17.2 15.3 20.2 36.7 25.2 25.3 17.3 15.3 24.9 19.7 19.5 14.6 27.0 25.4 25.7 38.1 51.7 33.0 13.8 21.8 25.2 24.4 31.3 28.5 57.6 26.9 56.9 15.8 39.6 34.3 20.0 16.1 19.9 60.1 23.4 47.2 21.9 25.7 45.8 59.8 37.0 24.0 55.8 58.2 31.5 15.8 70.1 25.2 30.9 20.1 43.7 31.4 23.7 27.6 22.1 21.3 22.6 27.6 18.4 44.7 25.6 17.5 20.9 15.0 19.1 14.4 54.9 38.3 48.7 21.2 52.7 19.6 5.8 13.4 14.7 19.3 19.5 34.1 40.7 27.1 27.0 22.5 40.3 33.5 30.4 2.8 29.4 17.3 23.8 33.4 14.7 18.6 19.9 23.4 26.3 19.1 20.5 18.9 19.0 19.0 19.1 19.3 20.2 32.0 121.8 102.4 12.7 40.2 21.7 28.6 51.8 44.9 34.5 36.8 46.0 37.6 54.3 65.1 29.5 6.2 50.2 24.0 33.6 64.6 47.3 134.7 42.9 26.7 34.5 31.8 36.0 16.1 65.8 34.0 28.8 22.4 33.0 46.9 16.0 23.2 48.8 32.7 50.5 16.1 39.4 50.8 24.7 22.1 115.0 29.2 27.9 19.6 11.2 25.3 53.4 27.8 18.1 16.1 38.5 41.3 23.0 53.8 36.8 50.5 58.5 61.8 34.7 32.9 35.1 32.1 101.6 50.4 40.5 19.9 22.2 28.5 34.7 46.0 31.7 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 ECSIT SITPEC ENSG00000130159 "ECSIT signaling integrator" Q9BQ95 19 11505929-11529172 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042979 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA042979: AB_10964063" "unprognostic (9.88e-2)" "unprognostic (3.57e-3)" "unprognostic (2.93e-1)" "unprognostic (3.55e-3)" "unprognostic (2.27e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "unprognostic (1.24e-1)" "unprognostic (2.92e-1)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (4.08e-2)" "prognostic favorable (1.48e-9)" "unprognostic (2.30e-3)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (5.95e-2)" 26.2 38.0 28.5 14.9 28.4 24.7 26.8 32.4 38.5 32.2 29.6 42.2 39.5 29.7 9.4 29.2 28.5 15.0 128.5 28.7 29.3 36.6 51.6 20.8 18.0 30.5 28.2 43.1 56.3 30.6 24.3 9.8 31.6 29.8 18.9 12.9 45.7 16.0 124.7 29.6 28.3 16.5 26.1 21.8 48.9 15.0 30.8 15.6 26.2 130.4 13.3 34.3 27.5 30.0 40.0 35.8 20.4 29.2 30.0 33.6 23.1 21.1 26.4 41.8 33.4 52.6 26.4 58.7 42.0 25.4 38.0 52.1 51.6 42.6 14.6 33.2 42.7 54.5 21.6 48.1 29.7 31.5 42.8 35.9 46.0 35.0 38.1 22.1 31.8 53.7 59.2 56.2 15.6 55.2 53.7 48.6 54.6 51.8 91.4 53.3 22.0 77.1 22.3 24.2 77.3 50.2 24.6 38.7 42.4 9.6 45.9 46.3 16.2 44.4 31.2 64.4 38.5 52.7 106.5 28.7 37.0 46.9 32.2 4.1 32.5 12.0 26.6 41.1 30.8 41.7 28.8 25.1 42.3 39.2 31.9 29.3 6.1 26.1 38.3 23.5 35.4 29.7 28.5 28.4 32.4 38.5 28.7 29.3 30.5 28.2 31.6 26.1 30.8 30.0 19.7 9.6 15.7 13.1 25.2 44.5 61.6 48.3 40.9 23.2 38.7 44.2 74.7 52.9 28.3 20.2 12.5 34.5 18.0 44.3 82.2 42.1 18.0 10.2 16.3 23.4 37.3 31.1 15.3 78.5 45.7 27.5 29.6 9.5 22.9 47.1 27.5 49.4 31.1 18.5 19.4 49.3 16.2 29.6 23.5 52.2 34.5 19.5 28.4 3.7 22.2 30.4 29.9 8.0 9.9 38.4 34.8 32.0 21.0 55.9 70.0 101.5 18.5 30.6 32.9 32.7 36.4 17.6 45.1 37.6 41.9 25.2 20.3 53.7 84.6 56.3 EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 210000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011663: AB_2096478, HPA064885: AB_2685382" "unprognostic (1.86e-2)" "unprognostic (8.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.46e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.73e-7)" "unprognostic (4.14e-3)" "unprognostic (4.49e-1)" "unprognostic (1.68e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (7.11e-4)" 28.3 24.5 12.5 29.9 14.0 25.0 25.7 15.1 17.8 18.1 10.4 25.0 21.5 19.4 19.6 38.8 15.8 21.5 28.7 14.6 14.1 24.5 35.3 18.4 30.4 13.7 12.7 17.1 26.3 22.9 9.4 26.3 13.6 22.1 26.7 21.2 18.3 22.3 49.4 23.7 21.5 27.0 13.8 19.8 19.8 33.4 13.5 27.9 27.9 40.6 33.5 39.1 19.0 16.6 265.7 86.4 59.8 92.3 56.4 63.4 127.8 115.5 68.3 127.4 110.7 101.6 92.2 118.7 57.0 87.4 85.7 100.4 139.1 110.3 192.7 86.9 51.9 76.9 80.0 70.4 59.2 82.7 71.9 52.4 62.6 113.9 172.5 49.8 105.4 73.8 132.6 89.6 127.3 131.3 113.7 64.7 61.1 157.9 142.9 85.7 99.0 84.6 78.2 120.0 85.9 60.7 83.0 96.5 91.1 52.3 164.5 70.8 81.3 167.4 180.7 82.0 124.4 77.0 90.4 180.7 97.1 145.3 110.2 51.4 50.6 33.0 47.4 71.0 58.4 55.4 54.5 51.7 70.1 45.8 50.3 51.5 6.9 58.6 62.8 48.0 64.3 70.7 12.5 14.0 15.1 17.8 14.6 14.1 13.7 12.7 13.6 13.8 13.5 16.6 64.1 28.9 40.2 17.3 44.1 142.8 88.2 77.2 37.5 22.1 32.0 30.1 92.8 30.0 55.8 22.0 12.5 78.7 38.0 23.3 70.5 89.6 81.0 34.6 48.9 60.3 13.1 64.2 21.7 63.0 104.7 51.2 34.1 44.8 35.5 35.7 26.4 39.8 70.4 37.0 20.9 30.6 61.1 37.9 51.3 33.4 31.1 40.7 51.6 15.9 61.3 32.2 36.0 15.1 23.8 70.8 18.3 40.6 56.7 79.9 26.6 65.1 35.0 35.2 26.3 60.7 85.9 204.9 96.3 49.7 130.4 93.4 46.1 57.9 39.7 79.1 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: AB_2675461, HPA061665: AB_2684580" "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 67.7 27.6 27.8 23.2 25.2 30.4 44.8 21.8 23.6 29.0 28.9 41.2 40.4 25.1 16.5 31.9 25.8 23.8 40.8 21.0 23.9 57.3 50.5 30.5 26.2 28.9 26.6 34.9 30.2 27.5 11.2 43.8 21.7 24.7 39.6 34.9 28.2 33.6 64.2 35.0 47.3 27.2 23.6 26.7 30.9 18.2 34.7 34.5 23.2 67.4 29.2 36.2 28.2 20.1 56.3 17.8 93.7 92.0 176.9 66.8 51.8 33.5 40.5 24.0 25.9 77.5 48.1 57.2 20.1 48.6 14.9 35.6 46.2 30.4 26.9 63.6 24.0 41.4 21.1 30.8 41.5 74.4 28.4 74.8 30.8 29.4 26.4 48.4 36.8 46.0 69.0 50.7 37.5 31.5 64.3 76.3 80.7 54.2 31.8 66.3 37.6 37.4 30.7 56.3 51.1 77.6 45.7 103.0 44.5 63.8 47.2 65.3 40.6 15.6 20.0 25.8 30.2 35.5 73.2 66.5 18.1 108.2 16.3 20.8 19.2 28.7 16.4 16.8 13.2 9.0 13.1 13.8 17.2 8.2 10.9 11.4 21.1 11.6 23.0 5.7 15.7 19.2 27.8 25.2 21.8 23.6 21.0 23.9 28.9 26.6 21.7 23.6 34.7 20.1 72.5 25.6 37.6 21.9 31.9 52.9 53.5 25.4 27.9 46.8 42.9 32.5 147.0 68.6 29.1 36.8 20.9 47.3 45.2 196.7 43.0 43.9 25.9 33.1 52.1 41.4 26.5 70.5 13.0 59.3 119.1 49.9 34.7 57.8 11.4 39.0 61.8 157.4 46.0 23.5 17.5 73.6 34.6 95.4 45.1 59.0 65.9 50.9 21.4 24.4 92.9 73.1 76.2 22.1 9.1 59.5 94.7 61.3 33.8 63.4 195.2 137.0 23.4 17.2 78.9 46.4 37.1 43.7 47.1 39.1 70.0 57.3 43.0 47.0 73.1 109.4 ELAC2 "FLJ10530, HPC2" ENSG00000006744 "ElaC ribonuclease Z 2" Q9BQ52 17 12991612-13018065 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 394.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019535 Approved Supported Nucleoplasm NA NA 9500 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA019535: AB_1848106" "unprognostic (4.24e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.24e-6)" "unprognostic (8.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-1)" "unprognostic (5.31e-3)" "unprognostic (3.09e-1)" "unprognostic (5.31e-3)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (8.09e-2)" "unprognostic (3.70e-2)" 30.7 35.8 13.7 23.0 14.6 22.7 24.6 14.7 14.3 21.7 18.0 28.7 23.1 24.7 17.1 31.9 25.8 21.1 38.1 13.8 15.0 28.6 32.5 19.8 28.0 16.4 14.6 19.8 23.1 33.8 12.5 23.5 15.3 26.4 32.7 22.5 20.4 33.6 60.2 23.8 21.1 33.6 17.1 28.8 24.8 28.1 13.4 28.4 25.8 35.7 37.6 24.6 18.2 22.1 76.4 102.1 69.8 81.5 53.3 53.9 44.9 75.4 59.6 119.8 79.8 84.3 34.8 127.7 84.9 69.9 45.0 96.6 133.6 80.6 113.5 65.7 163.7 73.0 82.1 54.7 40.7 64.7 99.4 47.3 70.6 88.2 80.5 51.4 88.3 71.5 108.0 34.8 88.7 58.0 112.0 58.3 62.2 132.9 80.7 84.1 122.2 82.2 62.0 59.2 37.5 54.6 97.4 61.0 39.2 394.4 59.1 26.2 82.7 152.3 47.6 57.0 116.3 24.7 51.6 53.3 57.6 64.2 54.6 26.9 31.1 19.2 41.6 41.2 43.4 37.7 39.1 40.7 48.4 34.4 39.7 36.2 4.7 53.5 46.8 30.1 53.4 46.3 13.7 14.6 14.7 14.3 13.8 15.0 16.4 14.6 15.3 17.1 13.4 22.1 11.6 6.4 10.8 6.8 18.0 10.3 10.1 16.7 16.5 11.3 12.5 10.8 28.3 12.8 12.9 16.5 2.1 59.3 15.6 13.2 19.6 27.4 6.4 13.0 13.1 14.1 8.4 24.0 9.8 26.0 32.6 16.6 17.3 14.2 9.5 30.4 11.7 28.4 28.2 11.8 9.2 13.5 24.4 14.2 7.0 5.7 10.5 10.0 14.2 3.7 14.7 16.1 14.4 7.1 10.6 25.9 16.6 21.4 21.6 13.5 15.2 19.5 12.2 14.6 52.6 10.1 14.9 26.4 24.4 22.2 14.5 33.5 15.9 59.0 20.7 8.2 EPRS1 "EARS, EPRS, GLUPRORS, PARS, QARS, QPRS" ENSG00000136628 "Glutamyl-prolyl-tRNA synthetase 1" P07814 1 219968600-220046530 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.3;Cardiomyocytes: 84.7;Cytotrophoblasts: 40.8;Extravillous trophoblasts: 59.3;Hofbauer cells: 42.6;Syncytiotrophoblasts: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026490, HPA030052" Enhanced Enhanced Cytosol NA NA 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA026490: AB_1855979, HPA030052: AB_10601466" "prognostic unfavorable (7.25e-4)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "unprognostic (2.60e-2)" "unprognostic (7.98e-3)" "unprognostic (1.12e-2)" "unprognostic (3.41e-3)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (7.13e-2)" "unprognostic (5.12e-2)" "unprognostic (2.32e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.62e-4)" 28.8 24.7 18.1 34.4 19.6 26.6 35.7 22.8 24.8 30.5 17.6 36.1 27.7 25.6 25.2 30.6 26.2 20.6 31.8 17.7 21.8 31.6 27.9 24.3 36.5 21.6 20.5 34.7 49.0 54.5 22.5 23.8 22.9 23.6 39.0 43.8 83.4 26.4 52.2 28.9 29.7 32.5 22.4 27.4 35.9 20.5 21.7 34.8 43.0 55.9 42.5 30.4 18.6 27.8 125.9 78.4 55.7 152.3 114.9 126.7 138.0 160.1 111.7 102.1 113.4 93.3 98.1 239.3 86.7 170.4 41.3 130.3 140.9 129.4 136.2 117.9 88.9 130.2 97.6 80.2 125.1 217.6 106.7 92.1 161.7 130.3 161.6 84.8 113.4 113.2 228.0 182.9 100.8 61.8 94.7 53.1 107.4 146.8 159.6 98.5 98.0 236.2 92.8 54.4 128.6 101.3 93.7 152.6 166.5 78.9 141.2 235.1 101.1 48.3 88.1 149.6 151.1 122.8 150.1 197.1 111.4 153.9 156.4 8.8 17.8 10.0 19.7 24.6 27.8 21.0 19.7 22.1 23.2 18.5 22.0 22.9 0.6 22.5 22.1 7.6 20.8 17.2 18.1 19.6 22.8 24.8 17.7 21.8 21.6 20.5 22.9 22.4 21.7 27.8 22.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.7 0.0 0.0 0.0 0.0 40.8 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 59.3 17.1 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 36.5 2.6 0.0 0.0 0.0 ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 159.2;Hepatocytes: 266.3;Proximal enterocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" 27.3 35.5 25.5 15.8 29.8 16.3 23.6 36.4 31.4 17.5 33.6 67.6 81.8 15.5 4.7 62.7 14.6 10.2 154.9 23.5 31.6 70.3 91.5 30.9 11.0 30.9 31.7 8.1 56.3 23.9 15.9 15.4 29.8 26.4 22.9 5.1 48.5 12.6 195.3 35.9 65.4 7.1 26.6 32.0 52.4 8.4 37.5 8.4 28.3 88.8 12.4 31.0 28.8 23.7 25.9 40.2 9.8 23.6 13.0 12.7 54.2 25.0 11.9 9.2 9.0 37.4 30.3 34.9 45.1 12.8 23.7 66.0 16.9 33.0 3.5 23.0 21.0 22.9 51.7 30.1 18.0 39.3 55.3 17.4 49.8 20.7 27.0 12.8 12.8 18.1 37.9 18.7 15.3 57.9 19.4 55.9 27.9 30.4 74.4 20.4 19.7 79.6 31.1 52.4 20.6 26.2 12.8 81.2 83.8 5.5 25.8 38.2 28.9 16.6 20.4 47.4 25.6 28.6 25.5 23.6 26.9 38.2 13.4 0.2 2.9 4.8 2.7 5.4 2.6 1.7 2.3 1.9 2.7 2.3 2.3 3.3 5.3 1.8 5.1 2.1 3.6 1.7 25.5 29.8 36.4 31.4 23.5 31.6 30.9 31.7 29.8 26.6 37.5 23.7 20.8 9.6 22.7 21.2 14.7 18.6 41.0 29.7 18.8 28.8 30.9 24.3 9.2 100.1 21.3 20.2 33.3 103.8 20.9 159.2 54.8 51.3 3.4 18.7 17.4 15.3 37.8 19.4 13.6 80.2 61.3 12.4 39.8 20.3 7.6 9.3 35.0 266.3 33.6 33.7 16.6 82.5 28.5 82.7 11.7 1.1 6.5 22.2 17.8 11.2 28.8 20.1 27.8 9.0 6.4 81.1 103.1 12.0 8.2 42.8 199.7 82.2 19.8 20.4 13.1 18.7 21.7 3.5 7.1 26.3 18.5 134.2 14.5 22.2 113.7 65.0 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 F8A3 ENSG00000277150 "Coagulation factor VIII associated 3" P23610 X 155456914-155458620 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 10.0;dendritic cells: 4.9;Erythroid cells: 8.2;Kupffer cells: 5.1;Plasma cells: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "eosinophil: 3.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "OE19: 35.9;U-266/70: 43.1;U-266/84: 43.1" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.83e-1)" "unprognostic (9.94e-2)" "unprognostic (3.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.94e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (7.03e-2)" "unprognostic (2.03e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (7.96e-2)" 7.1 6.4 3.7 5.1 4.3 7.0 5.5 2.9 10.8 5.0 2.6 5.7 4.3 5.3 4.9 4.9 4.3 4.1 7.4 3.9 4.4 6.1 11.0 4.1 4.8 3.5 3.4 3.6 6.5 17.8 3.0 2.9 4.0 3.9 2.6 3.3 5.8 2.9 12.0 4.1 5.6 0.9 3.4 6.5 5.3 1.5 3.8 7.9 5.4 5.0 2.3 4.5 3.8 4.1 0.3 0.1 2.2 0.0 8.9 6.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 12.3 0.1 15.4 0.0 12.1 2.6 0.0 0.0 0.0 6.0 16.0 10.2 0.1 10.1 22.1 7.5 0.0 0.0 9.4 7.1 0.0 5.9 0.0 0.0 0.0 15.5 0.0 23.2 0.1 4.2 35.9 0.0 0.1 0.0 11.9 9.3 7.8 0.0 4.4 8.4 0.0 0.0 19.8 0.0 13.8 5.4 21.1 0.0 15.3 25.4 43.1 43.1 0.1 6.3 0.0 0.1 0.0 0.3 3.2 0.7 0.1 0.4 0.3 0.6 0.5 0.4 0.3 0.3 0.4 0.5 0.1 0.2 0.4 0.1 0.1 3.7 4.3 2.9 10.8 3.9 4.4 3.5 3.4 4.0 3.4 3.8 4.1 1.3 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.6 1.8 1.7 0.6 0.2 10.0 0.0 1.8 0.0 2.0 4.9 2.2 0.0 0.6 0.0 0.2 0.2 0.9 0.0 8.2 0.0 1.5 1.5 1.2 1.1 0.1 0.0 0.1 0.7 3.8 2.3 0.0 0.0 1.3 0.0 5.1 0.0 0.0 0.0 1.6 0.0 0.0 2.1 0.6 2.1 0.0 0.0 1.3 0.3 0.0 4.8 0.4 1.2 2.6 0.0 0.9 0.0 1.8 0.8 0.0 0.0 2.1 0.0 2.9 3.4 0.2 0.8 0.3 FAM120A "C9orf10, KIAA0183, OSSA" ENSG00000048828 "Family with sequence similarity 120A" Q9NZB2 9 93451685-93566112 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019734, HPA055800" Approved Enhanced Cytosol NA NA 12000 "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019734: AB_1848369, HPA055800: AB_2682925" "unprognostic (5.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.03e-4)" "unprognostic (3.36e-1)" "unprognostic (2.33e-2)" "unprognostic (8.93e-2)" "unprognostic (5.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (3.71e-3)" "prognostic favorable (1.08e-7)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" 48.1 47.8 26.7 59.7 30.8 49.9 37.8 25.8 27.0 45.0 55.0 74.4 59.0 39.2 36.0 46.6 50.8 42.3 60.9 26.0 24.2 47.7 55.7 42.0 56.5 32.6 29.3 39.1 57.9 87.3 26.8 60.3 28.8 42.7 69.1 30.6 56.2 40.8 81.7 41.9 58.4 50.9 25.3 49.0 69.3 17.4 30.3 45.5 49.0 71.4 45.6 53.4 33.0 28.7 179.7 145.4 32.0 92.8 93.7 116.6 100.3 123.2 107.8 92.9 68.0 47.5 108.2 116.1 68.9 156.2 73.7 188.8 86.5 144.3 71.1 117.0 62.8 63.8 126.1 75.3 104.6 109.0 83.5 114.3 87.2 105.7 166.3 90.9 133.7 81.0 74.4 94.9 101.3 202.8 108.2 61.4 41.2 212.7 134.3 62.1 85.6 97.4 112.3 107.2 85.8 52.5 139.5 166.4 86.0 31.4 91.0 70.6 140.6 99.6 71.6 123.8 136.4 74.2 78.6 44.8 107.9 96.6 90.9 3.1 6.6 5.2 4.9 7.5 4.1 4.4 4.3 4.8 6.1 3.5 3.0 4.4 13.1 4.3 9.3 3.9 8.3 4.1 26.7 30.8 25.8 27.0 26.0 24.2 32.6 29.3 28.8 25.3 30.3 28.7 64.0 44.8 93.9 67.9 42.7 102.2 49.6 56.6 70.6 30.0 86.5 49.0 112.3 77.2 75.2 75.4 50.1 73.8 49.2 164.3 21.5 50.1 26.1 77.5 76.2 64.9 91.8 60.2 92.1 74.7 104.9 60.5 123.8 92.3 48.8 66.1 63.1 186.6 71.0 40.4 62.5 176.8 36.7 146.4 78.6 9.8 66.8 103.4 53.4 80.6 111.0 35.7 35.0 64.3 80.9 86.4 92.0 65.5 60.8 125.8 81.0 75.7 87.8 33.7 39.5 63.5 68.6 12.3 12.4 91.1 114.2 103.4 49.3 94.4 177.2 109.0 FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: AB_2668972, HPA051564: AB_2681536" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (5.78e-2)" "unprognostic (9.18e-3)" "unprognostic (4.13e-2)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.23e-3)" "unprognostic (1.11e-2)" "unprognostic (2.26e-1)" "unprognostic (5.53e-3)" "unprognostic (6.79e-3)" "unprognostic (2.98e-2)" "unprognostic (3.27e-3)" "unprognostic (7.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" "unprognostic (4.82e-2)" 6.1 4.7 4.7 5.5 4.5 3.5 4.8 5.8 7.1 4.2 8.0 6.9 9.3 3.9 2.9 8.8 4.2 4.0 21.8 4.6 5.3 9.4 13.2 4.0 6.4 5.2 7.0 5.6 3.3 6.4 2.6 7.5 5.6 4.4 6.4 11.5 5.1 4.6 25.5 3.3 6.2 6.2 5.1 3.7 4.7 8.4 6.3 5.3 6.3 33.1 7.3 6.3 5.0 5.7 24.6 13.6 9.4 8.8 10.9 11.2 13.6 16.5 15.3 18.2 21.1 18.4 11.6 24.9 20.2 11.8 33.6 11.5 18.2 20.6 29.5 17.4 8.4 17.7 9.7 13.0 12.9 30.3 15.9 9.7 15.9 17.5 61.6 12.7 11.9 14.8 24.2 13.4 21.2 16.8 18.7 19.5 10.6 47.7 13.5 15.2 22.3 29.1 15.1 15.3 6.0 10.1 14.5 21.1 40.0 13.4 10.8 14.2 13.2 46.4 45.7 29.1 20.6 15.1 20.1 28.8 24.6 15.6 18.9 3.5 5.3 3.3 6.2 8.0 6.8 5.7 5.2 5.4 6.4 6.3 6.4 6.2 0.8 6.0 4.2 4.0 5.4 3.8 4.7 4.5 5.8 7.1 4.6 5.3 5.2 7.0 5.6 5.1 6.3 5.7 14.9 9.6 8.3 13.7 29.8 55.3 14.8 28.3 12.5 63.2 11.0 11.2 66.4 12.8 14.6 7.3 20.9 20.6 11.6 9.1 21.5 18.6 20.5 16.7 21.6 18.3 11.4 5.9 18.0 8.8 39.0 17.4 10.2 32.7 7.0 36.7 6.8 20.7 20.0 30.3 23.5 10.0 10.2 9.5 43.4 6.1 9.3 26.5 8.8 15.0 11.4 19.0 15.5 18.6 24.8 12.6 4.1 10.1 14.2 19.9 12.1 29.8 5.0 29.9 6.6 16.3 15.4 31.4 32.3 20.6 57.3 25.7 16.8 45.6 20.5 14.8 FAM214A "FLJ10980, KIAA1370" ENSG00000047346 "Family with sequence similarity 214 member A" Q32MH5 15 52581317-52709817 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-698: 63.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039369, HPA040180" Approved Approved Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA039369: AB_10795250, HPA040180: AB_10794736" "unprognostic (1.75e-1)" "unprognostic (6.40e-2)" "unprognostic (4.54e-1)" "prognostic favorable (7.27e-6)" "unprognostic (1.08e-2)" "unprognostic (5.96e-3)" "unprognostic (1.32e-3)" "prognostic favorable (8.68e-4)" "unprognostic (6.84e-2)" "unprognostic (2.62e-1)" "unprognostic (2.91e-2)" "unprognostic (2.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.63e-1)" "unprognostic (3.22e-1)" "unprognostic (3.79e-2)" "unprognostic (6.94e-3)" 37.2 20.3 6.4 15.1 12.0 21.3 28.2 24.5 9.0 12.6 41.1 15.4 14.2 17.5 10.2 27.6 16.5 12.6 15.9 6.6 6.5 12.1 38.8 14.4 24.5 7.3 8.9 12.5 21.8 43.4 11.5 8.5 10.3 15.3 16.9 17.5 16.9 15.9 50.1 11.7 14.2 13.4 5.8 16.0 18.4 21.2 9.8 18.1 25.3 27.0 30.6 12.7 12.3 13.6 5.1 6.8 6.9 12.0 20.7 12.4 8.1 12.5 21.8 6.6 8.6 3.9 5.4 35.3 14.7 11.9 3.1 10.2 5.0 11.6 5.8 28.4 7.1 8.9 15.9 3.3 7.3 4.3 4.6 29.6 18.2 6.5 7.2 12.4 22.0 10.9 5.2 36.1 9.4 20.1 6.8 10.9 1.3 8.7 8.1 16.3 7.2 27.1 10.8 23.7 7.8 13.6 12.6 23.5 9.5 21.1 36.6 9.3 16.4 6.6 2.0 7.4 2.7 55.2 35.8 63.6 11.4 5.7 2.2 0.7 0.6 5.3 3.6 0.2 3.9 6.3 2.7 2.4 0.7 5.4 3.0 2.8 3.8 4.9 0.3 8.4 4.7 1.1 6.4 12.0 24.5 9.0 6.6 6.5 7.3 8.9 10.3 5.8 9.8 13.6 43.5 44.8 27.1 60.7 53.5 16.3 13.2 23.7 28.5 19.3 50.8 30.2 27.7 24.3 35.6 3.7 62.6 2.6 49.2 25.4 3.9 11.4 2.8 78.1 34.7 28.0 29.2 20.4 80.0 14.9 3.0 25.3 30.5 123.9 3.8 19.3 24.7 39.0 7.3 26.9 90.1 27.0 28.5 18.0 9.9 3.7 28.3 15.8 26.6 57.1 7.4 24.7 16.5 73.4 123.7 15.2 13.2 32.0 100.5 20.1 12.3 7.6 46.2 28.6 13.1 36.6 20.9 36.5 9.4 28.7 14.3 20.2 34.6 26.9 11.5 42.0 FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Uncertain Nucleoplasm,Mitochondria NA NA 5300000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA011651: , HPA071871: AB_2732188" "unprognostic (1.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.49e-1)" "unprognostic (4.80e-2)" "unprognostic (5.51e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" 59.5 57.9 22.5 25.1 38.7 19.9 46.5 41.1 30.5 38.3 41.3 71.2 101.2 52.5 21.5 59.7 40.8 37.6 116.8 21.9 25.7 57.7 51.5 36.6 19.2 59.0 37.2 39.5 68.4 48.2 58.1 38.6 54.8 52.5 30.1 9.8 41.2 39.4 175.7 49.1 64.7 40.6 35.7 30.2 59.8 45.1 37.1 16.7 50.5 77.0 15.0 60.1 38.3 71.1 29.5 67.1 72.3 152.1 110.2 66.3 39.2 71.5 92.7 41.9 54.2 67.6 76.9 30.2 104.2 90.8 37.3 55.2 27.6 48.4 35.7 40.5 48.5 35.7 38.8 53.2 81.0 21.4 22.5 74.4 58.7 67.1 48.1 119.8 74.1 39.1 42.1 6.0 44.9 140.0 22.1 25.2 89.1 44.2 31.1 66.5 48.0 120.5 73.9 29.6 83.1 73.9 107.9 58.3 61.5 63.3 81.5 31.4 63.3 76.7 25.2 43.8 21.3 15.6 7.1 37.6 54.4 30.1 104.9 11.7 17.7 13.3 10.1 17.7 5.2 7.1 8.9 10.0 18.0 9.5 10.0 11.3 6.1 15.8 17.2 6.5 9.4 13.9 22.5 38.7 41.1 30.5 21.9 25.7 59.0 37.2 54.8 35.7 37.1 71.1 20.2 9.6 12.6 0.0 7.4 0.0 11.3 0.0 9.6 8.9 23.9 19.7 0.0 21.5 5.0 31.3 25.0 58.7 8.8 25.2 7.9 49.4 27.9 22.2 26.8 18.1 35.2 14.5 0.0 26.1 48.8 21.0 23.4 33.2 8.8 59.2 22.9 23.5 25.7 10.1 0.0 26.4 0.0 14.4 0.0 78.1 16.8 10.9 0.0 0.0 39.6 11.1 10.3 0.0 0.0 18.4 41.5 21.8 5.7 14.8 102.1 18.6 6.6 12.0 19.7 16.9 20.1 29.2 30.8 18.2 0.0 66.2 6.8 73.3 40.4 10.7 FARS2 "dJ236A3.1, FARS1, mtPheRS" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5829192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 110.4;Early spermatids: 77.4;Excitatory neurons: 217.0;Inhibitory neurons: 122.6;Late spermatids: 78.8;Microglial cells: 106.8;Oligodendrocyte precursor cells: 186.5;Oligodendrocytes: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA018148: AB_1848426, HPA028836: AB_10601377" "unprognostic (2.73e-1)" "unprognostic (4.08e-3)" "prognostic favorable (5.14e-4)" "unprognostic (2.68e-1)" "unprognostic (1.94e-2)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (8.91e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.81e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" 9.4 12.0 8.1 9.6 10.9 11.7 11.0 6.1 10.8 8.8 22.9 10.6 7.4 9.2 7.3 9.8 14.9 6.8 16.0 8.4 9.6 14.2 14.4 9.6 12.4 5.8 6.7 7.8 10.3 13.2 9.8 8.9 6.5 7.3 11.3 6.8 8.4 8.6 19.7 11.4 7.9 9.8 6.1 9.8 9.9 11.7 10.8 12.5 14.4 17.9 11.0 8.8 8.9 8.6 14.2 13.4 14.1 14.7 17.1 20.5 11.6 15.1 17.9 19.4 19.2 18.0 10.7 19.7 23.1 14.9 18.9 13.9 18.2 23.9 20.2 59.5 12.2 7.9 11.0 16.1 8.9 18.9 11.4 16.5 24.0 21.9 15.8 11.4 23.6 21.8 23.7 4.5 14.6 14.5 20.6 21.2 8.7 21.7 12.9 20.0 17.6 38.9 18.7 16.4 23.9 11.8 14.1 11.0 17.6 18.4 22.1 20.6 13.7 20.7 9.4 12.3 19.8 9.3 34.2 10.9 11.6 11.1 26.6 0.1 14.7 5.2 23.1 16.7 20.3 20.0 20.5 21.2 26.0 17.5 22.3 22.1 1.1 24.6 11.9 15.5 28.0 17.6 8.1 10.9 6.1 10.8 8.4 9.6 5.8 6.7 6.5 6.1 10.8 8.6 10.4 9.6 13.7 110.4 15.7 14.8 18.5 17.7 10.2 8.8 8.9 12.1 18.4 12.8 8.5 9.2 2.1 19.5 10.5 6.9 27.4 14.6 77.4 10.2 7.6 10.9 10.7 13.9 217.0 12.9 20.9 10.5 13.3 7.2 22.2 14.3 11.4 12.0 15.8 0.0 122.6 9.4 14.2 12.5 11.6 78.8 6.2 17.4 5.4 106.8 9.4 14.2 8.2 186.5 122.4 7.8 8.6 7.2 16.1 6.6 7.4 30.7 19.3 11.1 0.0 10.1 10.8 19.2 9.4 13.3 13.2 10.7 16.2 24.2 11.9 13.2 FASTKD1 FLJ21901 ENSG00000138399 "FAST kinase domains 1" Q53R41 2 169528508-169573875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.8;Inhibitory neurons: 89.9;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043719 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043719: AB_2678635" "unprognostic (3.08e-3)" "unprognostic (1.63e-1)" "unprognostic (6.91e-3)" "unprognostic (8.03e-3)" "unprognostic (1.99e-2)" "unprognostic (3.84e-1)" "unprognostic (5.56e-3)" "unprognostic (1.15e-1)" "unprognostic (3.83e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (2.17e-1)" "unprognostic (4.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.41e-1)" "unprognostic (7.58e-2)" "unprognostic (7.62e-3)" 6.0 7.8 8.2 10.0 9.2 7.1 7.7 15.2 12.6 4.4 20.5 17.5 17.8 6.4 10.5 11.9 5.3 5.3 27.2 8.6 8.4 10.8 10.1 6.5 10.2 10.0 7.6 2.5 8.7 15.4 8.2 8.3 10.4 5.6 22.1 17.8 9.8 6.3 15.4 7.3 16.8 9.0 7.5 8.9 9.7 10.5 7.0 10.0 10.8 26.4 12.4 9.1 6.5 11.3 10.9 12.2 15.6 18.1 10.4 14.6 27.0 18.2 10.5 14.4 17.5 19.4 17.5 33.6 16.8 11.4 25.0 29.4 43.9 19.8 23.2 30.7 23.6 48.6 18.8 22.7 7.9 45.7 14.7 10.0 17.3 21.9 12.5 12.0 20.9 28.7 36.0 18.6 18.9 7.8 35.9 37.5 30.9 30.6 14.9 28.2 17.1 40.8 21.2 18.4 34.3 11.2 16.4 30.9 26.8 26.9 5.7 42.7 14.1 16.8 16.8 16.7 18.7 16.5 34.3 24.8 14.3 39.5 11.6 20.6 4.7 2.2 3.3 5.5 4.7 4.9 4.4 3.7 6.3 4.3 4.7 4.0 0.5 7.1 2.6 6.2 3.1 2.5 8.2 9.2 15.2 12.6 8.6 8.4 10.0 7.6 10.4 7.5 7.0 11.3 5.2 16.0 8.7 46.0 12.7 5.4 6.4 9.8 13.1 16.5 5.7 4.3 30.4 10.0 9.2 3.7 25.0 10.1 10.6 18.3 1.9 6.1 13.4 6.9 8.8 6.6 15.0 21.7 91.8 4.8 10.2 4.7 13.3 7.2 18.3 10.2 5.7 8.0 13.1 11.8 89.9 12.1 10.2 10.0 4.2 5.1 0.9 11.3 1.8 36.5 10.6 3.7 5.2 64.8 46.3 5.8 13.1 2.6 52.9 5.6 16.7 7.4 5.4 19.4 0.0 7.3 3.9 27.2 6.5 19.4 4.4 8.1 9.6 9.0 17.2 7.7 FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067191 Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA067191: AB_2685801" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "unprognostic (3.50e-3)" "unprognostic (1.36e-3)" "unprognostic (7.40e-2)" "unprognostic (2.69e-3)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.69e-2)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "unprognostic (4.87e-2)" "unprognostic (7.18e-2)" "unprognostic (1.03e-3)" "unprognostic (3.57e-2)" 14.4 14.0 5.2 12.4 5.9 11.4 17.3 4.8 6.2 12.8 7.5 15.0 14.9 15.8 8.8 15.9 12.9 11.5 24.9 5.7 5.3 17.4 27.2 11.8 14.3 5.8 4.5 15.7 11.6 18.4 6.9 13.0 6.5 13.3 17.0 11.2 11.2 11.1 31.5 11.8 12.5 15.7 4.4 11.2 13.3 12.0 4.9 13.1 17.8 36.6 17.2 20.4 9.6 4.8 30.2 27.0 24.7 28.1 27.2 32.7 46.2 34.3 29.0 57.3 32.4 48.3 32.0 37.4 37.5 35.5 66.7 40.0 30.7 47.4 50.4 11.7 19.8 29.4 25.6 46.6 33.1 64.3 26.5 35.2 48.8 43.8 47.2 29.1 39.3 27.2 56.4 18.6 42.8 25.3 27.3 27.4 44.0 28.2 51.2 23.7 38.1 38.8 39.4 49.7 36.0 22.9 26.6 44.7 41.3 36.8 20.9 33.4 30.8 35.0 31.5 24.4 36.3 18.5 32.9 48.0 40.6 29.2 29.5 9.6 21.4 5.2 19.2 21.4 21.5 20.1 21.3 20.2 31.0 17.3 28.0 25.2 1.4 31.2 16.5 14.6 18.7 20.5 5.2 5.9 4.8 6.2 5.7 5.3 5.8 4.5 6.5 4.4 4.9 4.8 17.8 28.9 11.4 19.6 20.3 23.7 33.7 28.8 32.5 18.9 11.1 12.2 23.2 7.2 22.8 12.9 22.9 28.2 15.1 6.7 9.8 19.2 30.9 14.5 23.1 14.6 7.3 11.6 41.9 15.1 22.4 21.2 27.5 14.9 5.1 17.5 9.3 17.6 14.8 6.7 40.3 10.5 12.2 7.9 9.4 8.0 9.6 10.8 5.4 25.3 12.9 9.3 8.2 26.2 23.2 12.1 8.2 13.9 20.0 13.7 8.8 12.7 15.9 22.8 13.1 19.3 17.4 37.5 12.8 24.5 21.5 25.7 18.4 18.6 13.1 22.6 FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 270.0;Excitatory neurons: 568.2;Inhibitory neurons: 578.0;Microglial cells: 205.2;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA036410: AB_2675109, HPA036411: AB_10669603" "unprognostic (8.15e-2)" "unprognostic (3.77e-2)" "unprognostic (2.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.58e-2)" "unprognostic (2.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.08e-2)" "unprognostic (5.98e-2)" "unprognostic (6.30e-2)" "prognostic favorable (4.60e-8)" "unprognostic (1.86e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.35e-2)" 15.4 13.8 11.8 7.8 13.1 5.9 10.4 7.5 15.3 10.8 3.8 10.1 10.6 9.9 8.9 12.0 9.0 9.1 27.0 12.4 12.5 16.9 14.2 8.9 8.5 9.0 12.2 9.3 10.0 26.0 5.7 5.9 9.0 11.8 10.4 25.6 9.8 13.7 55.8 8.7 10.9 11.7 10.5 10.7 10.1 8.6 11.8 10.1 24.6 41.7 10.7 8.5 4.5 10.3 8.7 8.5 9.6 17.7 15.8 16.4 6.4 10.4 23.3 8.4 11.3 1.7 17.9 9.7 16.0 16.9 13.0 3.8 7.7 11.9 13.0 9.8 6.9 9.2 9.0 4.2 8.2 6.2 10.1 11.8 17.4 7.8 5.7 16.3 10.1 3.9 1.3 12.2 18.5 6.5 5.4 7.9 1.3 6.7 7.9 7.6 12.8 12.7 11.7 11.9 8.2 14.0 13.6 11.9 13.4 6.6 9.4 14.6 11.0 18.9 5.9 5.9 13.6 9.5 14.3 7.0 16.7 9.4 12.6 0.1 0.1 0.8 0.4 0.2 0.4 0.2 0.4 0.4 0.2 0.3 0.4 0.3 0.3 0.2 0.1 0.4 0.2 0.1 11.8 13.1 7.5 15.3 12.4 12.5 9.0 12.2 9.0 10.5 11.8 10.3 13.2 19.2 14.5 270.0 13.9 16.8 7.4 7.5 6.8 37.2 18.6 10.2 38.3 17.2 8.3 29.5 56.3 4.8 12.8 22.8 17.6 7.3 5.6 8.5 9.7 12.3 29.9 5.7 568.2 13.1 6.5 12.1 12.2 10.7 16.5 12.2 21.0 21.4 8.4 30.3 578.0 21.7 2.0 21.0 14.1 5.4 14.0 9.9 16.0 205.2 13.1 20.8 12.3 302.6 256.1 13.3 16.0 16.6 10.7 8.6 14.4 15.0 6.1 50.4 0.0 16.6 9.8 9.5 3.9 10.6 24.6 4.5 12.6 13.8 16.6 8.8 FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Focal adhesion sites" "HPA003289: AB_2666879" "unprognostic (4.91e-2)" "unprognostic (5.57e-2)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (8.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.09e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-2)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" 10.9 7.5 6.5 8.3 7.3 8.9 12.3 8.8 10.5 10.9 7.4 10.3 8.5 10.0 7.9 12.4 8.2 9.5 8.1 7.6 9.1 13.6 17.4 8.9 10.5 8.5 7.4 11.3 7.6 13.7 4.4 9.0 8.8 10.0 10.6 8.3 7.9 8.5 12.5 21.1 7.7 9.8 8.0 8.9 8.5 7.8 7.8 10.9 9.8 14.2 10.6 11.5 9.0 8.9 24.6 10.6 16.2 17.4 16.6 19.0 26.7 24.3 19.7 16.0 15.2 14.9 18.7 11.8 24.4 22.3 10.3 20.9 24.2 23.4 27.4 17.0 27.0 15.0 12.8 10.7 20.7 28.3 18.8 18.6 27.7 23.2 41.9 18.8 27.1 15.0 24.8 16.4 29.1 8.1 14.9 14.4 38.6 32.3 22.8 15.7 23.1 22.3 30.2 16.1 26.2 28.1 25.1 38.0 27.4 16.9 20.2 28.2 31.2 19.8 15.0 25.0 46.1 17.8 22.3 18.0 24.5 13.7 39.3 7.4 6.5 11.8 5.8 6.0 7.2 8.9 5.9 6.8 7.8 9.0 5.9 6.6 4.2 8.6 6.9 3.5 8.8 4.6 6.5 7.3 8.8 10.5 7.6 9.1 8.5 7.4 8.8 8.0 7.8 8.9 15.0 6.4 10.6 22.5 16.8 34.3 25.5 11.3 9.6 20.5 14.7 11.7 11.4 7.2 13.5 11.0 22.9 14.2 12.3 17.2 9.8 13.2 30.3 15.9 13.0 16.4 18.5 17.4 48.8 11.5 13.1 12.7 7.1 22.9 14.0 12.6 14.3 23.4 13.9 18.5 43.8 12.7 14.2 17.7 16.3 14.8 13.1 16.8 28.4 34.7 16.4 12.6 7.2 45.8 43.7 17.7 12.2 13.2 15.4 21.5 12.0 22.8 11.5 18.6 13.1 14.9 12.7 24.7 26.8 17.2 39.1 23.0 18.9 10.9 14.6 30.7 FBXO3 "FBA, FBX3" ENSG00000110429 "F-box protein 3" Q9UK99 11 33740939-33774543 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002467 Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA002467: AB_2666602" "unprognostic (1.87e-1)" "unprognostic (2.81e-1)" "unprognostic (6.07e-2)" "unprognostic (1.25e-1)" "unprognostic (3.71e-1)" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (8.53e-2)" "unprognostic (5.21e-2)" "unprognostic (2.42e-1)" "unprognostic (1.47e-1)" "unprognostic (7.36e-2)" "prognostic favorable (2.46e-9)" "unprognostic (6.96e-2)" "unprognostic (1.92e-1)" "unprognostic (1.27e-1)" "unprognostic (3.19e-2)" 21.2 24.2 18.1 14.8 21.6 26.9 27.5 20.7 24.6 21.4 19.0 21.4 18.1 24.8 24.2 33.6 23.3 21.5 46.3 20.3 19.8 47.0 42.0 19.7 18.3 16.5 16.8 28.9 27.1 56.8 17.7 16.5 17.5 25.6 23.7 33.9 23.0 25.5 124.1 28.9 20.5 24.5 17.2 19.1 23.5 25.2 19.0 20.4 34.3 98.8 21.4 20.8 22.5 19.0 22.1 19.2 25.8 27.6 30.4 23.8 15.6 25.7 25.6 20.4 25.3 22.1 21.6 14.6 17.7 28.2 25.1 37.2 34.8 33.9 34.1 14.7 48.2 7.5 28.4 18.3 19.4 17.4 16.9 24.2 33.8 14.1 22.3 29.7 27.3 10.6 25.9 28.4 23.2 14.9 13.0 10.2 13.1 49.4 29.5 9.9 57.5 20.8 29.5 27.5 36.3 20.0 36.4 24.8 19.6 24.6 35.8 13.2 25.2 25.2 22.0 35.9 22.0 15.7 22.1 24.5 22.5 13.4 25.4 25.9 11.9 18.0 21.6 11.8 24.4 16.2 25.5 24.6 12.8 20.0 32.1 22.4 12.8 25.1 15.5 6.6 34.3 15.8 18.1 21.6 20.7 24.6 20.3 19.8 16.5 16.8 17.5 17.2 19.0 19.0 33.3 35.3 17.2 31.3 28.9 48.8 64.2 32.0 35.3 56.8 24.5 14.7 42.4 21.5 31.0 25.8 27.1 22.7 28.9 22.6 56.7 49.6 130.8 17.3 19.2 31.7 23.9 32.8 45.1 25.3 28.7 30.7 17.3 21.8 16.5 25.8 32.5 41.0 12.3 57.2 37.9 18.8 54.9 15.0 20.1 51.3 29.8 11.9 28.4 22.5 15.2 46.7 40.2 30.7 40.1 34.9 25.2 27.1 28.3 33.3 23.2 63.6 34.4 52.4 59.2 26.2 37.1 64.2 27.3 43.6 67.5 36.5 32.9 19.4 16.7 50.4 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812911 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol NA NA 280000 "Cluster 13: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 52.3 46.8 32.9 60.2 36.1 27.5 54.1 42.8 44.6 42.0 41.0 47.8 34.8 42.5 33.1 54.8 51.0 38.8 51.0 30.7 36.1 57.1 69.0 36.1 78.3 34.5 35.7 62.5 30.4 41.5 16.5 58.2 35.8 41.3 50.6 18.3 31.8 37.3 112.2 43.4 33.9 47.8 35.0 46.7 40.3 65.5 38.6 66.0 42.6 92.1 85.7 66.3 31.9 43.3 204.9 267.0 177.0 96.3 253.2 119.2 232.4 204.1 190.6 290.6 348.6 413.7 310.3 384.7 307.0 188.0 231.6 210.9 319.7 395.6 333.7 122.5 173.8 232.9 201.1 334.8 128.8 281.6 163.9 123.4 186.7 243.7 232.2 98.7 209.7 140.9 191.3 173.3 254.5 179.7 273.9 142.4 231.4 146.0 209.6 254.3 235.1 187.2 163.1 290.5 195.2 132.0 200.8 307.0 319.3 169.2 246.3 174.7 238.2 202.0 239.7 187.3 364.0 104.9 171.3 305.0 132.2 229.6 337.8 132.2 102.3 84.7 189.2 135.4 255.3 168.8 215.6 186.7 141.0 160.0 201.8 193.2 37.8 203.7 134.1 134.7 249.2 287.2 32.9 36.1 42.8 44.6 30.7 36.1 34.5 35.7 35.8 35.0 38.6 43.3 88.9 19.2 41.4 32.7 112.0 239.5 101.3 82.4 148.0 37.1 74.8 60.7 62.3 44.3 66.2 64.4 16.7 94.0 91.7 47.3 78.2 69.6 49.6 80.6 104.4 112.1 50.2 96.1 25.7 53.0 94.6 98.0 70.3 87.2 73.6 73.8 76.8 169.4 78.2 57.2 30.6 59.4 50.8 81.2 195.0 30.1 65.0 73.3 87.2 37.5 83.7 54.3 45.3 29.7 45.3 59.2 42.9 57.2 89.3 160.0 33.5 80.0 74.2 36.6 39.5 111.6 90.7 58.0 89.3 155.6 256.4 67.3 99.6 72.2 78.5 98.0 G3BP2 KIAA0660 ENSG00000138757 "G3BP stress granule assembly factor 2" Q9UN86 4 75641849-75724589 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018304, HPA018425" Enhanced Enhanced Cytosol NA NA 47000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA018304: AB_1849350, HPA018425: AB_1849352" "unprognostic (2.42e-2)" "unprognostic (5.79e-2)" "unprognostic (8.70e-3)" "unprognostic (2.23e-1)" "unprognostic (6.98e-2)" "unprognostic (5.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.04e-1)" "unprognostic (6.83e-2)" "unprognostic (3.79e-1)" "unprognostic (7.38e-2)" "unprognostic (7.88e-2)" "prognostic favorable (6.65e-5)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (6.99e-2)" 37.6 41.5 32.6 50.9 35.6 69.2 50.3 24.2 48.5 47.2 12.9 61.7 52.4 45.1 32.1 49.5 55.2 49.7 47.8 33.7 51.7 67.5 65.3 46.0 60.2 26.0 28.8 32.0 42.2 56.0 28.2 38.4 32.4 77.8 58.0 46.8 37.0 49.2 115.1 25.5 62.6 55.0 24.0 48.0 47.5 60.5 40.0 66.5 74.6 119.5 61.2 65.8 25.8 30.0 96.8 96.6 160.5 131.1 134.8 136.6 54.1 141.6 144.6 96.2 101.5 128.5 137.1 197.1 125.5 120.1 87.0 68.8 170.1 176.0 136.6 111.4 66.2 185.7 95.7 141.7 119.8 188.4 146.2 109.9 144.4 114.6 122.8 129.1 172.1 114.9 140.9 139.2 150.7 63.0 218.4 63.1 154.1 140.3 36.3 159.8 199.2 96.3 112.3 125.8 124.1 141.1 105.7 151.0 201.9 165.7 75.1 90.9 178.5 95.3 76.5 107.7 81.7 136.2 133.9 195.2 135.5 122.9 122.7 83.1 36.2 62.4 50.0 47.8 76.4 35.1 48.1 55.8 41.1 28.2 46.9 51.5 30.8 59.6 64.1 18.5 44.1 64.1 32.6 35.6 24.2 48.5 33.7 51.7 26.0 28.8 32.4 24.0 40.0 30.0 72.8 54.5 100.7 26.1 126.3 89.0 81.7 53.2 114.4 61.4 71.8 55.2 79.1 20.0 81.0 53.3 50.1 36.4 133.0 92.2 41.1 59.0 213.8 84.7 57.8 69.8 135.4 43.9 70.6 68.9 49.3 56.7 65.2 80.0 105.7 76.7 51.0 77.7 45.7 70.7 74.9 107.9 50.8 75.9 131.3 228.8 26.4 86.1 60.5 30.9 85.3 29.3 53.5 36.7 59.1 94.8 66.6 39.9 117.7 84.5 88.3 104.1 85.8 69.1 19.7 57.2 91.9 63.2 74.8 79.8 77.7 41.3 186.2 99.5 75.6 88.3 GATD3A "C21orf33, D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI" ENSG00000160221 "Glutamine amidotransferase like class 1 domain containing 3A" P0DPI2 21 44133610-44210114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 178.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.0;Granulosa cells: 4.6;Hofbauer cells: 8.6;Proximal tubular cells: 4.8;Theca cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 156.3;U-266/70: 128.2;U-266/84: 117.9" HPA018517 Supported Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (9.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-3)" "unprognostic (6.57e-2)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (8.61e-3)" "unprognostic (9.43e-2)" "unprognostic (4.60e-3)" "unprognostic (1.97e-3)" "unprognostic (1.40e-1)" "unprognostic (6.96e-2)" "unprognostic (1.30e-2)" 21.3 25.3 10.4 7.7 11.8 1.3 18.6 12.2 50.3 18.9 8.2 19.0 2.0 12.1 25.7 19.8 27.4 1.3 68.4 10.3 11.9 51.0 78.2 12.3 8.0 15.0 13.5 18.8 18.2 18.3 16.0 5.8 12.8 16.6 1.0 6.1 18.2 7.8 60.2 17.1 15.7 1.0 12.3 16.3 19.2 11.3 13.4 8.2 15.2 178.6 20.7 18.3 15.1 12.7 1.8 3.7 2.6 0.7 34.4 34.0 52.0 64.2 39.7 49.2 38.9 82.4 0.6 156.3 0.9 0.2 1.6 0.8 0.4 35.3 25.1 35.0 77.7 8.0 11.3 49.0 38.3 3.1 1.1 0.4 2.8 15.7 1.9 29.5 2.2 40.0 31.7 56.5 19.7 6.5 1.6 3.9 1.4 4.9 9.0 1.6 0.8 28.4 2.6 1.2 55.8 0.6 1.3 1.6 52.7 1.0 2.8 4.4 33.8 22.7 1.4 38.1 0.8 128.2 117.9 2.5 1.7 10.2 29.5 10.8 16.4 9.6 16.9 24.9 15.6 27.4 21.5 21.3 3.7 28.1 17.6 15.1 7.6 21.0 40.4 17.6 18.5 23.1 10.4 11.8 12.2 50.3 10.3 11.9 15.0 13.5 12.8 12.3 13.4 12.7 4.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 2.5 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 3.9 1.6 0.0 2.6 1.1 2.1 0.0 0.0 0.0 2.5 3.6 1.9 0.0 1.9 0.0 4.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.6 0.8 11.9 0.0 0.0 GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favorable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" 26.7 25.0 12.3 21.7 13.2 24.1 27.8 18.1 21.3 14.1 16.8 30.1 24.9 17.2 20.8 24.1 13.4 17.5 39.0 13.0 15.5 43.7 49.6 18.8 20.7 14.5 13.2 12.7 26.4 40.1 12.0 25.7 15.3 19.6 31.5 46.4 21.0 21.9 63.0 15.2 19.8 20.9 13.7 16.4 23.9 23.5 14.1 16.6 32.1 60.2 20.7 23.5 12.9 15.7 92.2 55.9 25.5 32.0 41.8 30.6 34.2 42.6 49.8 75.9 57.4 73.2 58.7 73.9 54.7 39.2 32.0 55.9 62.5 47.8 84.3 40.6 33.7 56.1 34.6 34.3 48.6 76.7 35.9 37.3 55.7 43.8 41.0 17.6 50.2 43.0 71.7 50.3 67.9 56.9 49.6 30.6 55.7 97.0 29.8 49.8 28.0 132.6 51.0 38.3 48.9 42.8 63.8 96.1 79.1 19.9 132.1 60.0 28.0 46.4 21.0 69.4 74.1 82.7 61.4 138.9 41.8 65.0 52.4 18.9 19.3 13.8 22.2 27.2 28.6 17.0 19.3 23.0 23.3 16.4 22.1 23.9 3.0 25.4 22.0 11.2 17.4 18.4 12.3 13.2 18.1 21.3 13.0 15.5 14.5 13.2 15.3 13.7 14.1 15.7 31.4 19.2 19.0 17.0 26.1 21.5 26.0 20.9 20.5 57.3 23.0 11.9 54.8 22.8 18.9 12.9 31.3 31.6 20.1 22.2 11.7 19.9 15.4 12.4 20.2 36.6 19.3 29.0 39.8 25.0 17.6 20.9 22.4 14.8 19.0 17.7 22.5 61.6 29.0 15.2 43.9 24.5 30.5 20.4 21.5 7.6 22.7 21.7 17.8 18.7 33.8 27.3 16.5 22.6 43.3 20.3 10.5 17.0 19.2 21.7 22.1 37.9 25.1 51.6 13.1 21.5 23.4 34.4 31.6 20.1 21.0 30.8 22.3 41.4 28.9 22.0 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GIN1 "FLJ20125, GIN-1, TGIN1, ZH2C2" ENSG00000145723 "Gypsy retrotransposon integrase 1" Q9NXP7 5 103086000-103120138 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037402, HPA061362" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "HPA037402: AB_10672790, HPA061362: AB_2684491" "unprognostic (3.89e-2)" "unprognostic (5.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.53e-1)" "unprognostic (7.98e-2)" "unprognostic (1.81e-1)" "unprognostic (4.64e-2)" "unprognostic (3.02e-2)" "unprognostic (4.66e-2)" "unprognostic (3.01e-2)" "unprognostic (9.60e-3)" "unprognostic (1.20e-1)" "prognostic favorable (1.63e-4)" "unprognostic (1.89e-1)" "unprognostic (4.39e-1)" "unprognostic (3.14e-2)" "unprognostic (3.08e-2)" 2.2 4.0 1.8 2.9 2.0 0.6 4.3 3.0 3.5 3.4 1.3 2.5 2.5 3.2 3.6 2.2 3.2 1.7 6.7 1.7 2.3 4.3 4.3 2.3 3.6 2.2 2.1 5.4 2.9 5.2 1.1 2.4 2.1 3.5 3.2 7.2 3.0 3.6 7.8 2.4 2.5 2.8 2.2 3.0 3.2 4.7 2.2 4.2 4.1 6.9 3.5 2.7 1.7 3.2 4.0 4.7 5.8 4.0 2.8 7.1 4.4 5.6 3.8 4.0 3.6 2.6 5.3 2.5 5.0 2.2 3.5 4.7 5.4 7.9 5.3 3.3 4.4 3.5 4.2 3.1 5.5 3.5 2.3 2.6 8.7 3.6 7.3 4.8 3.0 4.1 3.3 3.6 6.4 2.9 4.6 2.3 4.6 3.3 7.0 4.0 6.4 6.0 5.3 3.4 5.1 3.2 4.3 2.8 5.6 4.1 8.7 5.9 2.4 4.0 2.5 4.4 4.2 4.4 3.5 3.6 5.3 5.6 3.5 0.4 1.4 2.8 1.7 1.8 2.0 2.6 2.4 2.6 1.7 2.6 2.8 3.0 2.1 2.3 4.0 1.7 4.4 1.4 1.8 2.0 3.0 3.5 1.7 2.3 2.2 2.1 2.1 2.2 2.2 3.2 5.4 9.6 5.3 11.4 6.1 0.9 4.7 12.5 4.0 9.4 3.5 4.4 18.7 2.8 6.5 5.5 0.0 7.7 3.6 2.9 23.5 8.0 1.6 4.3 6.5 3.9 4.2 1.7 9.1 4.3 4.9 4.7 4.1 3.1 16.5 6.1 3.3 4.5 5.5 0.0 12.2 4.0 10.2 3.5 2.0 0.7 5.0 4.8 0.0 4.7 4.8 9.3 5.2 23.1 23.7 4.0 4.7 6.8 2.6 3.6 4.5 8.8 7.6 13.4 6.6 4.0 6.5 23.8 12.2 2.7 2.0 8.2 6.1 5.7 3.6 3.0 GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 777.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 723.9;Extravillous trophoblasts: 751.2;Proximal enterocytes: 968.3;Proximal tubular cells: 1165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 569.0;RPTEC TERT1: 462.1;U-87 MG: 441.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 6300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB008634: AB_1616672, CAB069419: AB_1616670, HPA046431: AB_2679663" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.62e-3)" "unprognostic (9.31e-3)" "unprognostic (1.99e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (2.61e-1)" 82.1 101.4 32.5 80.0 34.9 173.7 37.2 46.3 52.4 28.2 29.0 57.2 194.7 12.7 10.1 13.6 17.2 50.8 102.7 47.3 37.1 247.4 143.6 71.9 61.5 52.0 42.1 10.9 10.9 82.4 23.7 102.0 39.8 28.5 47.4 6.9 59.2 25.6 777.4 38.3 170.3 25.7 34.3 64.9 40.2 4.9 43.6 75.6 18.9 55.9 80.4 53.1 20.9 37.9 22.2 97.1 8.4 18.0 211.3 310.4 1.6 326.5 569.0 35.9 62.9 31.2 10.2 86.2 45.7 99.0 83.0 9.7 12.9 156.4 100.5 75.7 24.1 62.8 63.5 248.1 386.6 67.2 182.8 184.4 23.2 219.7 21.3 81.1 75.3 179.3 8.2 51.3 262.3 7.9 121.4 133.0 22.2 3.3 111.6 186.1 66.8 107.9 462.1 16.8 23.6 12.5 85.3 47.8 39.4 22.0 13.0 66.0 78.0 91.9 101.9 74.6 14.4 37.1 202.0 70.4 441.3 170.6 19.7 48.9 727.2 901.6 222.9 483.8 313.6 142.9 205.0 166.7 459.8 107.8 201.4 186.1 783.8 113.4 411.2 166.6 457.7 781.7 32.5 34.9 46.3 52.4 47.3 37.1 52.0 42.1 39.8 34.3 43.6 37.9 77.5 22.4 28.4 3.6 74.1 17.2 62.9 330.5 8.6 2.2 57.9 31.5 154.9 65.8 183.6 93.8 0.0 47.4 130.0 173.8 723.9 60.4 0.3 83.4 49.0 47.1 31.7 63.1 8.7 96.0 751.2 63.1 35.7 118.0 31.6 3.5 46.4 206.9 271.5 0.0 8.0 89.9 65.1 304.9 276.1 2.3 19.0 232.3 69.4 12.2 340.0 7.8 302.8 2.0 2.4 113.5 291.3 13.9 200.2 89.5 968.3 1165.9 124.1 3.9 19.7 22.1 67.0 0.6 1.6 4.1 20.6 285.3 97.7 11.7 85.4 214.6 GLYR1 "BM045, HIBDL, N-PAC, NP60" ENSG00000140632 "Glyoxylate reductase 1 homolog" Q49A26 16 4803203-4847288 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017022, HPA048226, HPA050136" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "CAB017022: , HPA048226: AB_2680320, HPA050136: AB_2681028" "unprognostic (4.72e-1)" "unprognostic (1.65e-1)" "unprognostic (3.19e-2)" "unprognostic (8.20e-2)" "unprognostic (2.77e-1)" "unprognostic (1.97e-2)" "unprognostic (3.86e-2)" "unprognostic (3.18e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" "unprognostic (1.41e-1)" "unprognostic (8.47e-3)" "prognostic favorable (8.74e-7)" "unprognostic (3.34e-1)" "unprognostic (4.38e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-1)" 34.4 35.0 26.9 43.4 27.9 43.4 27.7 21.2 27.7 31.7 35.9 46.0 43.3 30.1 24.6 37.7 45.4 30.4 41.7 29.3 26.5 46.9 38.3 32.8 41.7 24.2 26.1 24.9 35.8 60.4 31.5 33.7 22.8 40.2 43.9 41.9 43.5 37.5 44.1 33.6 40.4 37.2 22.5 39.2 44.7 20.3 26.6 45.7 40.2 37.8 43.2 36.5 26.9 22.4 43.2 47.5 76.4 47.9 66.1 52.5 73.4 80.0 59.0 59.6 50.7 66.7 75.5 69.8 74.0 74.2 49.0 47.3 96.4 67.0 53.4 114.0 59.4 72.4 57.7 47.7 37.3 117.6 129.6 50.2 52.3 56.3 41.5 57.6 77.2 65.0 122.8 58.8 65.6 69.8 96.6 64.8 91.0 65.0 35.2 123.5 59.9 86.5 73.4 64.0 93.1 47.1 86.4 80.7 37.1 83.1 90.3 123.9 86.1 41.1 46.0 186.2 50.3 49.0 73.1 145.5 29.3 57.9 85.5 10.3 14.1 7.8 9.0 12.7 8.0 6.2 6.0 8.9 9.7 9.6 6.2 5.6 28.1 7.0 20.8 10.8 6.5 8.2 26.9 27.9 21.2 27.7 29.3 26.5 24.2 26.1 22.8 22.5 26.6 22.4 28.6 38.5 47.3 35.6 29.9 19.1 18.7 17.1 19.4 36.8 30.3 23.6 42.3 28.6 37.3 31.3 29.2 28.0 31.1 54.9 66.5 24.4 11.3 58.2 36.7 28.1 46.3 45.6 43.6 19.4 31.6 23.0 26.0 43.0 31.6 27.4 26.7 53.0 32.0 45.4 37.0 41.2 18.3 39.3 23.9 10.3 24.2 35.9 21.4 32.8 54.5 25.0 28.8 28.6 35.8 29.2 38.8 16.1 26.5 29.0 38.9 54.7 73.3 42.6 19.7 24.6 36.1 21.9 24.5 23.4 24.2 35.7 26.1 28.1 38.8 21.3 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" 23.6 33.6 13.5 28.0 15.3 28.4 42.4 29.7 17.6 24.7 25.0 21.3 19.7 28.6 12.8 16.3 21.0 23.1 20.4 13.4 15.0 30.1 32.7 23.9 22.3 16.2 16.5 23.0 23.1 40.5 16.2 27.2 15.6 18.3 21.7 15.4 25.4 20.3 57.6 18.4 19.0 33.2 15.4 21.2 26.8 24.2 15.7 22.1 20.0 39.9 27.4 24.6 18.8 16.8 39.0 42.4 49.7 38.9 53.1 64.1 43.7 82.7 70.8 61.4 63.6 28.7 76.1 53.8 56.6 68.7 75.4 22.0 58.7 37.3 78.8 58.0 32.4 63.0 49.0 26.5 31.0 6.8 87.1 40.6 26.9 64.0 23.0 52.5 64.1 52.7 47.9 61.5 63.4 16.5 60.0 17.3 53.1 71.3 22.5 34.7 49.8 29.2 36.4 57.5 32.4 44.7 32.2 43.9 89.1 56.5 60.9 42.4 47.0 63.0 43.8 73.0 62.6 33.0 47.9 58.7 51.9 36.9 63.1 16.0 17.0 7.8 12.5 15.9 11.6 8.6 9.6 12.6 21.0 9.9 8.5 8.5 3.8 5.8 14.3 8.0 9.7 13.8 13.5 15.3 29.7 17.6 13.4 15.0 16.2 16.5 15.6 15.4 15.7 16.8 20.0 3.2 31.2 0.0 14.5 0.0 13.2 0.0 11.4 16.9 50.2 19.6 0.0 27.1 13.6 11.0 10.4 33.9 18.4 10.8 3.9 41.3 40.6 14.1 19.4 21.7 17.0 21.5 0.0 39.8 42.5 13.1 27.0 29.2 2.5 21.2 18.2 62.4 27.1 15.2 0.0 14.2 0.0 28.1 0.0 58.7 12.8 31.7 0.0 0.0 31.2 11.8 9.2 0.0 0.0 44.9 11.3 10.5 23.9 27.7 13.3 28.2 5.8 15.1 6.6 20.3 11.6 4.3 14.8 10.1 0.0 40.4 16.7 23.0 11.1 18.2 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPD1L KIAA0089 ENSG00000152642 "Glycerol-3-phosphate dehydrogenase 1 like" Q8N335 3 32105689-32168709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.4;tongue: 253.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 154.1;Distal enterocytes: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 136.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.23e-1)" "unprognostic (3.12e-2)" "prognostic favorable (7.05e-4)" "unprognostic (2.63e-1)" "unprognostic (9.67e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (5.71e-5)" "unprognostic (2.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.33e-15)" "unprognostic (1.50e-1)" "unprognostic (1.99e-1)" "unprognostic (2.31e-3)" "unprognostic (5.51e-3)" 39.0 44.7 18.2 8.3 20.1 6.9 30.6 17.2 21.2 22.8 27.1 40.1 26.5 11.6 9.8 40.9 19.1 9.2 124.8 21.2 20.5 34.2 2.8 31.3 9.0 19.2 18.6 16.6 21.6 32.8 5.9 20.8 19.3 59.9 36.7 9.8 22.0 41.2 158.4 10.3 29.0 16.6 20.5 12.8 29.7 6.1 18.3 6.8 40.3 253.1 10.2 31.0 12.9 21.9 11.1 10.0 3.5 15.3 49.3 11.9 136.1 8.8 3.1 9.2 7.1 10.7 5.2 19.4 13.2 6.2 11.3 12.6 23.4 9.3 11.6 8.3 21.4 11.3 13.2 16.8 12.4 29.4 39.3 35.5 12.1 8.9 12.5 9.4 16.3 15.7 8.0 6.1 7.3 15.1 12.6 11.0 2.1 27.6 44.8 23.1 15.7 40.0 14.6 66.8 15.1 15.0 6.7 61.1 25.0 4.8 38.7 14.1 8.6 10.5 4.9 16.3 23.6 4.3 2.0 19.3 24.0 22.3 6.0 0.5 2.8 5.7 3.3 3.2 8.0 1.5 4.1 4.0 5.6 1.2 2.5 3.7 1.4 7.4 2.1 4.4 8.8 2.8 18.2 20.1 17.2 21.2 21.2 20.5 19.2 18.6 19.3 20.5 18.3 21.9 10.2 28.9 41.8 1.3 4.1 4.6 5.3 3.5 8.6 4.1 20.3 10.7 154.1 2.8 18.6 9.2 2.1 36.4 10.8 75.2 39.2 2.0 8.0 5.3 4.4 10.5 7.8 6.9 23.1 3.7 6.1 10.5 17.3 9.2 39.3 9.8 13.2 0.7 10.0 1.7 23.7 21.3 26.4 6.3 5.7 20.7 5.9 4.4 8.8 24.4 2.3 32.9 7.2 3.0 11.1 4.3 21.6 12.8 8.7 13.8 33.9 18.4 15.0 3.9 0.0 8.0 8.7 0.8 2.1 32.3 7.0 27.1 10.4 3.3 26.9 8.5 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA039764: AB_2676669, HPA047793: AB_2680157" "unprognostic (1.68e-3)" "unprognostic (1.11e-2)" "unprognostic (9.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.27e-3)" "prognostic unfavorable (3.98e-5)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" "prognostic favorable (2.65e-6)" "unprognostic (5.81e-2)" "unprognostic (2.85e-1)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" 25.6 18.9 10.4 16.3 11.7 15.4 24.4 12.9 12.9 15.7 11.6 15.6 8.1 17.8 15.2 16.3 18.5 13.8 34.2 10.0 11.0 31.4 32.1 16.9 22.9 12.2 11.2 23.3 19.9 29.2 11.1 21.3 12.8 22.2 13.1 23.4 24.2 18.0 47.9 11.1 10.6 19.5 13.0 16.2 15.6 41.3 10.9 18.1 21.2 51.1 18.1 17.6 13.8 14.9 42.3 65.8 43.2 42.8 47.5 30.1 57.6 57.1 34.1 62.2 50.3 59.7 24.6 81.5 38.5 31.0 46.0 37.9 54.2 50.5 83.9 46.9 50.6 47.7 33.8 50.5 33.2 75.2 42.2 32.2 31.4 61.1 39.5 34.9 45.6 67.0 82.1 17.9 44.3 28.2 69.8 142.8 53.4 58.6 64.8 23.5 59.9 62.2 39.3 37.8 34.7 34.8 57.7 39.0 49.9 55.0 66.7 87.7 25.4 51.6 38.0 51.3 66.6 24.7 68.0 85.1 38.2 68.5 60.3 41.0 54.4 79.4 30.0 71.9 32.8 46.5 32.0 34.2 51.1 47.9 40.5 26.9 27.4 28.4 75.3 62.5 30.1 41.6 10.4 11.7 12.9 12.9 10.0 11.0 12.2 11.2 12.8 13.0 10.9 14.9 23.8 25.6 34.5 3.3 24.5 29.8 49.3 57.9 15.9 18.8 28.8 32.5 43.8 20.0 36.0 33.1 14.6 62.4 26.6 3.8 107.6 30.4 111.1 24.9 24.6 20.8 8.3 26.9 4.3 21.3 74.0 25.4 8.2 21.5 31.0 18.6 18.2 38.1 94.7 21.9 5.6 9.1 40.7 19.1 17.7 22.6 19.9 33.2 16.0 14.0 39.6 25.7 19.6 3.5 6.4 22.4 11.0 23.7 20.9 55.5 5.3 72.1 34.2 33.0 26.3 31.0 35.3 187.2 77.6 20.8 25.4 46.7 19.2 22.1 13.7 40.2 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 GSE1 KIAA0182 ENSG00000131149 "Gse1 coiled-coil protein" Q14687 16 85169525-85676204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.0;Syncytiotrophoblasts: 182.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 24.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 174.6;K-562: 205.4;T-47d: 200.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036365, HPA042090" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA036365: AB_10601762, HPA042090: " "unprognostic (1.12e-2)" "unprognostic (6.29e-2)" "unprognostic (1.12e-1)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (6.41e-2)" "prognostic favorable (5.20e-4)" "unprognostic (2.29e-3)" "unprognostic (1.32e-3)" "unprognostic (8.41e-2)" "unprognostic (8.46e-2)" "unprognostic (3.81e-1)" "unprognostic (1.88e-1)" 27.2 15.2 1.4 14.2 0.7 31.9 22.0 24.4 7.9 16.9 0.0 17.9 15.9 15.1 5.0 12.7 15.9 10.6 23.2 3.9 3.0 12.3 14.2 17.7 11.3 4.5 5.8 23.7 23.4 38.6 28.0 31.7 2.1 12.7 11.5 14.4 30.3 13.6 37.9 18.8 14.8 14.2 0.0 18.4 20.8 14.7 2.0 40.7 19.3 9.3 8.7 13.0 14.1 0.7 19.3 33.6 22.0 55.5 13.9 12.7 174.6 25.3 17.4 13.9 5.2 29.0 25.6 11.2 29.9 28.9 12.5 17.9 35.1 9.7 7.0 21.2 29.7 82.4 33.6 36.5 17.9 38.5 44.8 23.7 22.7 14.9 7.1 14.5 3.7 65.7 205.4 2.0 4.6 129.9 138.1 33.9 38.4 20.7 9.9 89.7 7.4 29.1 12.6 7.2 142.7 99.3 49.8 91.8 4.7 19.9 200.7 94.6 6.4 28.3 35.5 7.9 6.9 30.0 19.5 65.3 16.2 23.8 25.4 2.8 0.7 2.2 1.4 1.3 1.4 1.6 0.5 0.9 1.2 1.5 0.2 1.0 0.6 0.9 3.3 0.0 0.0 0.6 1.4 0.7 24.4 7.9 3.9 3.0 4.5 5.8 2.1 0.0 2.0 0.7 52.9 67.3 68.1 30.3 16.6 14.0 7.3 11.6 21.1 65.0 39.6 16.8 37.0 25.8 24.1 38.6 146.0 52.9 25.5 33.6 1.9 14.9 4.3 48.8 34.7 27.0 59.7 65.6 53.2 12.4 75.9 21.7 39.3 61.6 43.6 80.9 17.2 34.7 12.3 35.3 45.4 67.5 20.3 15.1 24.0 5.5 47.2 17.5 10.6 19.7 12.2 7.1 35.0 14.1 13.7 17.9 20.9 61.3 18.6 14.3 12.6 6.2 30.5 62.3 6.6 15.5 10.1 2.3 18.3 33.5 30.0 182.2 21.5 55.8 25.7 12.3 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favorable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favorable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 150.9 180.9 77.5 135.9 82.5 187.0 159.1 82.7 89.2 154.5 141.0 217.9 317.2 95.2 110.7 154.0 144.7 140.6 271.7 75.7 82.7 257.2 449.3 125.1 185.0 85.2 84.0 71.1 138.0 308.2 79.7 104.2 85.3 111.4 230.8 26.9 213.0 96.4 238.6 132.6 277.1 106.6 79.8 236.5 163.4 85.1 83.3 96.2 160.1 324.1 183.7 129.5 112.4 88.6 150.7 106.1 14.7 130.1 224.2 319.7 68.8 87.0 148.4 76.3 150.8 64.5 375.2 85.4 120.8 126.7 114.5 222.4 57.5 136.2 66.0 165.0 62.3 69.6 80.9 102.9 154.1 84.7 108.4 290.4 164.3 88.0 62.0 113.1 205.3 109.5 99.3 100.9 207.2 116.2 87.3 152.9 34.7 291.3 158.6 73.9 2.4 169.6 266.1 81.6 59.7 81.4 159.4 256.3 137.4 88.3 123.6 117.0 122.2 41.0 37.7 108.5 75.2 171.0 86.5 20.0 148.5 336.0 86.6 351.1 537.1 210.7 298.5 597.9 289.7 254.5 554.6 386.4 445.2 183.2 281.3 274.6 165.0 188.3 641.7 187.0 800.5 917.1 77.5 82.5 82.7 89.2 75.7 82.7 85.2 84.0 85.3 79.8 83.3 88.6 181.9 70.5 95.6 17.0 134.1 114.2 174.9 244.0 118.4 11.6 181.9 198.2 172.9 211.6 219.5 121.4 12.5 295.3 151.4 301.6 291.6 160.5 561.3 102.7 95.8 117.0 153.6 63.3 25.8 120.3 132.0 96.4 185.5 92.9 145.1 47.4 155.3 322.1 304.2 8.4 28.8 252.8 154.6 288.3 174.1 1160.2 72.7 195.8 151.2 16.9 228.5 85.9 194.7 16.6 14.3 104.5 505.2 50.8 130.0 82.9 670.0 620.2 154.0 15.4 85.5 65.9 121.7 6.9 10.3 166.3 116.4 183.7 250.7 150.7 366.5 218.9 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GTF2I "BAP-135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBSCR6" ENSG00000263001 "General transcription factor IIi" P78347 7 74650231-74760692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004595, HPA026638" Supported Enhanced Nucleoplasm NA NA 55000 "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB004595: AB_628345, HPA026638: AB_1857959" "unprognostic (3.47e-1)" "unprognostic (2.26e-2)" "unprognostic (3.63e-1)" "unprognostic (1.61e-1)" "unprognostic (3.21e-1)" "unprognostic (1.11e-1)" "unprognostic (7.08e-2)" "unprognostic (2.53e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-1)" "unprognostic (8.80e-3)" "unprognostic (1.28e-1)" "prognostic favorable (6.35e-6)" "unprognostic (7.70e-2)" "unprognostic (1.60e-1)" "unprognostic (1.19e-1)" "unprognostic (5.88e-2)" 61.2 75.3 32.5 48.2 36.4 32.7 52.2 36.7 35.7 57.5 64.7 41.9 52.8 57.5 41.3 54.9 66.9 47.0 51.2 32.3 31.5 70.9 57.6 52.3 56.7 31.2 33.7 64.4 49.8 106.0 42.9 56.1 31.6 64.2 39.9 82.8 69.4 54.1 84.2 62.9 48.0 61.5 31.0 47.6 67.6 25.4 35.1 70.6 118.0 56.8 68.8 49.4 38.8 46.4 136.4 110.4 222.6 219.9 120.6 106.7 46.3 83.7 76.9 90.5 89.6 76.9 161.6 165.4 33.7 104.1 121.6 116.3 221.1 101.3 116.2 126.4 115.9 85.6 128.0 107.7 72.3 159.5 126.9 98.8 84.7 68.8 70.0 132.6 123.3 55.2 165.3 80.0 110.9 126.8 133.7 147.5 243.6 286.9 67.1 146.0 77.5 133.1 118.7 232.2 185.5 236.3 153.0 226.5 78.7 185.8 116.4 105.2 111.7 123.6 66.8 62.8 108.8 90.2 83.3 256.2 70.9 95.8 126.6 20.4 10.0 17.4 11.3 7.3 16.6 22.1 14.6 16.7 14.6 24.1 17.8 17.4 4.1 21.3 6.6 23.0 8.7 9.7 32.5 36.4 36.7 35.7 32.3 31.5 31.2 33.7 31.6 31.0 35.1 46.4 118.5 80.1 60.6 55.8 80.3 60.2 83.3 136.3 125.7 276.4 140.7 113.7 30.3 210.1 106.3 119.5 283.5 112.6 101.5 46.0 56.7 155.4 37.1 368.7 201.3 98.2 112.5 91.7 68.6 83.0 64.4 78.8 117.8 321.8 13.3 246.1 115.3 101.0 80.3 250.7 74.1 71.0 73.2 106.7 53.7 39.8 152.8 76.0 55.2 46.9 122.3 200.9 101.0 102.5 98.1 132.5 70.6 193.0 81.4 117.6 150.6 110.2 233.3 184.3 85.5 96.8 87.8 34.1 51.9 145.8 91.9 72.2 60.5 172.7 63.9 124.3 GTPBP10 "DKFZP686A10121, FLJ38242, OBGH2" ENSG00000105793 "GTP binding protein 10" A4D1E9 7 90335223-90391453 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021076 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "HPA021076: AB_1850411" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-2)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (3.56e-1)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (5.38e-2)" "unprognostic (2.32e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.76e-5)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (2.72e-3)" 8.5 7.2 3.2 8.9 3.2 6.5 10.6 5.3 5.7 7.0 1.9 8.8 8.8 7.6 6.4 8.2 6.3 5.6 10.1 3.0 4.3 12.5 18.7 5.7 11.0 3.3 2.8 8.6 7.6 8.1 4.5 6.1 4.0 6.9 9.6 7.2 6.1 5.3 12.3 6.8 7.1 7.1 3.9 7.3 10.7 11.3 3.5 12.7 9.8 10.0 9.7 9.5 5.6 4.3 33.9 21.1 14.1 21.3 17.1 15.3 23.2 21.2 13.9 19.5 15.4 31.1 25.0 42.2 34.6 14.5 41.6 21.3 32.4 28.3 25.3 26.5 16.6 17.4 12.8 16.4 16.3 51.0 14.9 18.3 12.1 32.4 64.3 15.5 11.5 35.0 64.8 30.1 17.6 34.6 35.8 14.5 17.4 30.8 25.5 22.7 41.3 35.2 14.3 18.4 17.4 16.3 27.2 41.3 41.2 20.1 20.0 21.9 21.1 27.3 31.9 48.9 41.2 22.6 30.7 59.3 20.5 35.4 29.5 23.6 5.3 9.4 6.3 7.4 10.9 11.7 10.2 7.7 6.4 9.2 10.8 10.2 5.1 7.8 4.5 5.7 13.3 5.6 3.2 3.2 5.3 5.7 3.0 4.3 3.3 2.8 4.0 3.9 3.5 4.3 11.0 12.8 21.1 21.5 17.6 5.9 8.5 13.5 9.6 12.6 9.8 11.0 14.3 7.2 17.0 16.5 14.6 7.6 9.7 6.2 13.7 8.7 21.8 8.8 12.1 9.4 9.6 12.8 29.7 15.8 7.2 10.8 10.2 8.9 12.0 12.7 8.6 14.3 6.4 5.0 35.5 7.4 14.2 7.5 6.0 4.4 9.3 7.4 7.2 42.2 7.4 11.2 9.2 36.7 50.8 10.2 4.9 9.4 7.4 8.4 7.8 21.8 15.3 12.4 6.6 18.9 10.5 26.2 18.9 12.0 6.1 6.7 15.5 15.6 9.1 8.4 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 13.9 16.1 6.2 13.7 6.7 20.5 12.6 7.0 8.4 8.4 8.4 21.6 23.1 9.6 7.6 19.3 8.5 10.8 39.0 7.4 6.8 17.6 22.9 11.5 15.6 6.7 6.2 8.3 9.9 25.1 8.3 13.1 6.4 9.5 21.6 13.5 15.2 10.0 64.4 17.6 20.2 12.5 6.2 14.5 15.3 10.2 6.7 13.0 10.8 57.0 17.1 22.3 11.6 6.1 54.3 60.5 31.8 28.5 25.6 25.2 29.2 52.0 43.0 67.8 57.5 70.7 38.5 34.3 26.3 46.1 80.8 49.8 63.2 51.8 70.5 30.8 48.0 34.1 80.8 38.6 47.3 40.9 39.4 24.2 37.4 67.9 46.5 37.9 49.1 26.1 63.1 41.1 46.3 72.5 28.0 31.4 51.5 36.6 70.1 27.3 59.9 65.4 44.0 44.8 20.9 24.2 54.8 58.7 38.2 66.7 45.6 27.1 48.7 42.4 23.6 110.4 47.0 26.9 29.0 47.8 35.5 28.8 42.7 25.6 47.8 30.1 20.2 66.4 19.0 39.0 19.6 18.2 62.2 34.7 17.1 22.1 13.1 19.1 57.4 56.2 23.5 19.0 6.2 6.7 7.0 8.4 7.4 6.8 6.7 6.2 6.4 6.2 6.7 6.1 15.5 6.4 4.8 2.3 20.8 54.8 53.2 57.0 22.8 5.3 16.1 13.7 49.3 17.2 33.3 16.5 0.0 32.9 12.4 44.6 50.9 34.9 13.7 19.0 10.4 21.0 10.8 32.8 3.8 29.3 37.9 17.1 12.8 16.7 13.3 10.4 15.7 18.5 41.8 8.4 4.5 19.2 67.1 21.0 44.1 2.3 13.4 23.5 24.9 1.9 27.9 13.0 7.2 2.0 2.7 68.4 31.9 10.5 18.4 63.5 46.4 36.0 28.9 7.1 6.6 12.5 20.1 24.4 28.4 21.8 46.0 40.9 12.0 15.6 30.2 88.6 HDAC3 "HD3, KDAC3, RPD3, RPD3-2" ENSG00000171720 "Histone deacetylase 3" O15379 5 141620876-141636849 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005583, HPA052052, CAB072336" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "Golgi apparatus" "CAB005583: AB_562296, CAB072336: , HPA052052: AB_2681708" "unprognostic (6.65e-2)" "unprognostic (1.96e-1)" "prognostic favorable (3.39e-4)" "unprognostic (1.17e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-2)" "unprognostic (3.16e-1)" "unprognostic (5.56e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.65e-6)" "unprognostic (1.85e-1)" "unprognostic (1.63e-2)" "unprognostic (2.28e-3)" "unprognostic (2.17e-1)" 24.3 39.8 7.8 22.7 8.4 37.3 25.3 7.8 9.5 25.7 9.9 23.3 18.7 23.5 26.4 34.1 26.5 20.3 24.4 8.7 8.4 24.2 39.6 21.4 32.7 8.2 8.0 26.0 28.4 44.9 18.4 22.4 7.9 20.6 24.5 16.4 25.5 21.9 40.2 40.8 23.5 26.1 8.5 27.8 23.3 15.8 8.5 38.3 24.1 34.1 42.7 26.2 25.8 8.2 59.8 40.2 74.0 109.5 68.5 54.3 47.0 42.6 93.5 94.8 134.8 86.5 49.7 86.4 54.0 56.2 67.3 51.2 72.9 98.8 117.0 74.6 79.0 68.8 33.3 50.4 48.1 83.5 60.1 47.0 63.2 55.3 71.3 49.6 61.9 76.8 67.6 44.7 61.5 55.8 92.1 72.9 63.9 36.8 31.0 65.8 76.2 62.3 49.9 59.7 60.2 49.4 57.0 57.1 71.7 46.2 61.8 52.3 32.1 58.3 36.1 45.8 71.8 36.6 47.8 82.1 48.8 78.6 50.8 41.3 51.7 39.6 34.1 53.8 45.5 47.8 42.5 41.9 107.5 47.5 45.9 38.5 21.5 35.1 46.8 55.1 55.6 43.8 7.8 8.4 7.8 9.5 8.7 8.4 8.2 8.0 7.9 8.5 8.5 8.2 19.1 9.6 13.2 16.6 36.0 44.2 26.8 38.1 37.0 33.2 29.0 25.5 15.9 18.6 19.6 12.9 60.5 55.3 43.8 18.5 21.5 33.4 10.4 10.0 21.0 21.3 18.0 50.7 40.6 35.4 51.6 28.8 19.9 10.2 18.4 33.9 21.4 18.7 38.8 50.5 38.2 19.7 28.5 19.5 44.9 4.2 22.4 31.7 32.0 10.3 51.1 33.3 38.1 22.1 21.9 33.4 16.3 22.2 36.3 28.7 19.5 20.5 10.8 36.5 26.3 18.1 24.7 25.4 27.5 38.1 51.4 61.2 30.3 42.6 25.9 30.3 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 99.7;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 5.0 5.1 4.9 4.2 5.5 3.3 7.4 9.1 5.8 5.1 9.4 4.7 4.2 4.0 7.0 6.1 5.3 4.2 3.7 6.3 5.4 6.4 10.6 4.9 3.7 5.9 4.6 3.8 7.6 10.6 8.8 4.1 6.3 8.9 4.4 6.1 8.5 6.6 13.3 2.8 4.9 4.5 4.1 3.1 5.7 5.7 5.4 3.3 10.7 6.2 4.3 5.4 2.8 5.5 23.8 10.4 13.0 9.6 14.8 13.7 13.3 13.0 12.7 7.1 7.0 10.8 11.0 10.6 6.4 21.4 13.0 8.2 5.9 11.6 5.5 21.0 9.2 16.4 9.6 6.7 14.9 8.6 11.0 10.2 17.0 10.6 23.6 15.5 9.0 12.0 19.7 31.9 17.4 14.2 4.6 5.4 21.8 16.7 11.3 7.1 7.5 11.2 10.8 24.8 8.3 9.9 16.7 8.8 14.8 10.0 16.2 9.1 10.5 9.1 2.7 8.9 7.8 25.6 19.8 7.1 14.6 11.1 10.7 1.9 0.8 0.8 3.6 2.0 2.9 1.2 1.9 2.3 0.8 1.3 2.4 2.2 1.2 4.8 5.1 1.9 1.6 1.8 4.9 5.5 9.1 5.8 6.3 5.4 5.9 4.6 6.3 4.1 5.4 5.5 3.0 9.6 12.5 46.4 4.1 3.3 9.2 5.3 6.8 12.8 9.4 7.4 4.5 8.6 8.4 12.9 22.9 8.9 5.1 3.5 7.9 7.8 5.6 8.0 8.0 3.8 6.0 7.4 86.2 8.1 5.4 5.1 9.7 8.0 5.7 7.9 4.2 18.5 4.6 18.5 99.7 5.2 4.1 5.1 2.1 4.3 4.4 4.0 0.0 45.9 3.2 5.6 8.2 79.9 80.1 9.0 2.9 7.2 4.2 7.8 8.0 6.1 9.2 14.2 0.0 9.0 6.8 5.2 11.5 8.7 4.0 5.1 5.5 11.1 5.4 6.9 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HUS1 ENSG00000136273 "HUS1 checkpoint clamp component" O60921 7 47963288-47979615 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026787 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA026787: AB_10601431" "unprognostic (1.87e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (2.65e-1)" "unprognostic (1.73e-3)" "unprognostic (6.93e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (1.96e-3)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (4.19e-2)" "unprognostic (3.89e-2)" 6.3 8.4 4.4 5.7 4.7 8.3 5.2 5.4 7.4 5.4 6.2 7.4 6.8 5.8 5.6 8.5 4.2 4.1 7.0 4.5 4.7 7.1 11.2 6.3 7.5 5.0 5.7 5.5 6.3 9.7 6.3 7.6 4.9 5.3 8.6 3.5 6.1 4.2 11.1 4.4 5.3 7.8 4.4 5.3 4.3 3.6 5.5 6.9 6.3 6.9 7.6 6.9 6.1 5.4 8.8 16.7 10.7 18.2 9.8 10.0 9.0 20.2 8.4 11.1 10.2 11.8 10.8 9.3 10.2 15.5 57.4 13.6 11.9 15.8 24.3 10.5 8.2 5.2 16.5 9.5 10.3 9.5 12.4 7.0 20.2 12.8 7.0 9.1 18.8 8.4 10.1 10.5 31.8 11.7 13.0 24.8 13.2 15.7 15.2 8.1 7.9 14.7 15.8 24.1 14.6 18.8 13.4 19.8 9.9 20.3 15.3 22.6 9.4 22.1 15.0 31.9 23.0 8.3 19.6 17.2 17.6 17.6 35.4 18.6 14.2 8.2 12.6 13.4 12.7 9.1 11.9 13.7 12.6 10.0 12.5 12.9 3.3 14.9 9.0 14.9 14.1 9.5 4.4 4.7 5.4 7.4 4.5 4.7 5.0 5.7 4.9 4.4 5.5 5.4 20.0 3.2 6.2 4.2 22.8 9.7 16.2 12.7 11.4 11.3 9.0 7.1 16.8 4.3 13.2 11.0 10.4 17.9 18.6 26.1 21.5 17.1 29.6 11.0 17.5 16.5 6.7 8.6 5.9 14.7 31.1 11.2 7.1 16.1 23.5 14.3 10.0 16.7 23.7 13.5 6.2 10.8 14.2 12.8 17.7 48.2 9.3 23.3 17.8 8.4 20.0 8.1 15.5 6.6 8.2 18.6 37.9 11.7 15.8 10.7 16.5 15.8 7.4 14.9 0.0 12.6 10.7 12.8 6.7 11.7 7.2 31.9 20.8 11.0 9.4 15.0 IARS1 "IARS, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase 1" P41252 9 92210207-92293756 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 47.6;Cytotrophoblasts: 29.8;Extravillous trophoblasts: 31.7;Hofbauer cells: 17.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029806 Approved Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA029806: AB_10601818" "unprognostic (1.32e-3)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (8.23e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.98e-7)" "unprognostic (2.00e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (4.96e-2)" "unprognostic (3.67e-2)" "unprognostic (1.40e-2)" "unprognostic (2.88e-2)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (7.76e-3)" 22.2 24.3 6.3 28.8 5.8 13.2 27.4 8.8 11.5 26.4 10.7 29.1 17.9 32.5 15.1 31.8 27.7 16.1 32.2 6.8 10.7 28.4 19.6 18.9 28.3 5.9 7.3 20.4 40.1 52.3 11.7 27.7 8.6 27.7 33.3 25.2 25.5 31.6 43.1 21.7 16.2 42.6 3.6 19.7 31.4 20.0 5.2 27.5 64.6 47.2 37.6 28.2 11.7 6.9 150.7 154.9 83.3 132.2 110.5 142.2 126.8 156.4 146.2 118.8 138.5 52.2 99.0 216.0 54.9 231.4 130.5 194.9 254.4 197.9 149.3 126.1 97.9 135.3 128.3 62.8 235.6 181.3 90.6 134.1 194.9 208.9 348.9 78.3 123.6 230.1 229.2 189.8 145.0 79.3 173.2 31.6 139.7 294.5 143.3 116.2 129.3 103.0 72.9 72.6 110.2 91.5 118.2 117.0 128.8 87.8 95.2 94.4 101.3 89.5 104.6 149.3 119.1 134.8 156.4 99.5 218.7 133.3 173.3 2.8 5.9 0.7 11.9 7.0 16.4 13.9 11.8 11.9 12.7 9.7 12.8 12.7 0.5 19.5 6.3 4.8 10.9 9.0 6.3 5.8 8.8 11.5 6.8 10.7 5.9 7.3 8.6 3.6 5.2 6.9 7.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.6 0.0 0.0 0.0 0.0 29.8 7.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 31.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 17.4 1.1 0.0 0.0 0.0 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 IBTK "BTBD26, BTKI, DKFZP564B116" ENSG00000005700 "Inhibitor of Bruton tyrosine kinase" Q9P2D0 6 82169986-82247754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 190.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023826, HPA048438" Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA023826: AB_1851378, HPA048438: AB_2680392" "unprognostic (3.13e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.72e-2)" "unprognostic (1.75e-2)" "unprognostic (2.48e-1)" "unprognostic (2.78e-1)" "unprognostic (5.93e-2)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (1.90e-2)" "unprognostic (8.81e-2)" "unprognostic (3.02e-2)" "unprognostic (1.08e-2)" "unprognostic (7.33e-2)" "unprognostic (1.09e-1)" "unprognostic (7.27e-2)" "unprognostic (9.78e-2)" 7.3 14.3 2.5 8.1 3.3 3.7 7.9 3.2 2.6 8.9 3.1 8.6 8.4 8.0 4.8 8.3 7.6 6.0 10.0 2.0 2.7 10.3 22.2 7.0 6.7 2.8 3.4 8.8 11.0 12.3 4.8 6.3 3.0 7.7 10.4 8.5 8.9 7.4 21.4 4.1 8.4 7.4 3.5 6.5 11.5 4.0 3.1 7.2 10.3 20.9 7.2 8.6 5.9 3.5 8.3 17.0 12.2 10.3 14.4 19.8 5.5 19.3 21.1 15.5 16.6 9.0 9.6 16.4 11.9 22.8 20.5 8.8 9.8 10.8 18.5 22.5 7.3 17.6 8.8 14.1 20.2 20.7 10.3 17.1 17.6 14.8 36.8 14.5 15.7 11.4 16.4 10.0 16.7 12.7 7.2 6.7 5.5 13.0 9.1 10.2 25.7 6.5 23.2 18.9 8.2 9.0 13.0 16.1 10.3 10.8 15.1 12.5 12.6 9.0 6.7 11.3 15.6 10.3 17.1 7.5 9.9 13.4 11.9 1.3 1.2 1.0 1.8 1.1 2.4 1.6 1.8 1.6 1.9 1.0 1.7 1.6 0.0 1.0 2.3 1.4 2.7 0.8 2.5 3.3 3.2 2.6 2.0 2.7 2.8 3.4 3.0 3.5 3.1 3.5 26.1 41.7 47.6 46.4 33.5 13.6 42.8 19.4 15.4 55.6 27.4 19.0 64.9 40.0 41.2 38.6 54.2 23.9 25.9 62.2 15.6 37.5 4.2 37.4 28.1 27.3 38.9 37.4 102.6 51.6 16.4 34.1 117.8 57.0 36.8 38.1 21.8 77.0 26.7 52.2 97.9 49.3 6.1 33.4 26.1 4.1 25.7 36.1 23.2 44.0 43.6 32.7 25.7 80.9 190.0 52.1 55.5 21.1 68.2 53.4 31.1 28.3 42.1 39.2 26.3 42.0 29.1 21.2 22.9 41.1 11.6 9.4 29.8 67.0 41.9 64.4 IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" 22.6 25.1 11.5 19.9 12.6 9.7 9.6 17.0 14.7 12.4 21.4 26.2 36.6 13.7 7.8 17.0 11.0 9.0 62.5 14.8 13.2 16.8 14.2 11.9 17.1 13.0 13.1 10.8 13.0 54.7 6.9 12.1 15.2 13.9 26.7 26.2 16.2 16.1 79.4 15.8 36.0 17.1 10.1 15.3 11.9 16.9 14.3 35.0 11.2 99.7 24.8 17.7 11.1 14.8 43.8 58.5 10.4 36.5 25.5 26.1 22.6 50.8 24.5 40.6 30.5 41.6 25.8 91.6 36.8 29.9 59.9 64.2 98.2 39.3 37.0 40.7 32.2 35.7 62.4 19.2 21.8 69.8 48.8 19.9 23.6 39.4 41.2 19.3 25.7 32.0 46.4 35.9 26.0 41.4 51.4 17.4 12.9 25.2 21.8 29.3 44.4 28.1 33.4 58.3 41.4 15.8 58.2 82.1 47.1 19.1 32.7 37.4 26.4 47.6 43.9 63.1 83.1 41.5 99.9 48.8 33.2 64.9 37.7 16.9 27.9 8.3 15.1 52.9 16.4 27.7 14.7 13.5 43.5 32.6 15.2 16.4 15.5 17.3 54.8 144.4 17.7 23.2 11.5 12.6 17.0 14.7 14.8 13.2 13.0 13.1 15.2 10.1 14.3 14.8 18.0 9.6 16.5 22.9 30.6 56.0 58.7 51.4 33.0 35.1 10.9 12.6 17.5 14.3 22.6 25.8 37.5 38.3 63.0 69.0 82.2 26.1 52.2 19.9 13.4 17.5 19.2 9.4 45.9 17.9 40.4 21.2 11.7 9.2 27.3 14.5 10.8 22.4 26.5 26.9 53.3 37.6 69.2 24.9 28.6 23.4 20.8 26.4 26.6 12.2 16.0 29.3 12.3 19.6 17.9 21.5 37.9 23.7 33.2 40.6 49.6 48.1 38.2 34.6 13.1 23.8 25.5 45.7 26.2 28.4 41.2 68.4 17.7 37.2 56.0 42.0 IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" 55.6 61.3 51.8 33.4 53.0 57.9 54.7 60.8 57.9 56.6 49.4 70.8 73.9 57.3 35.9 62.4 49.8 29.6 185.8 53.8 56.3 71.0 60.5 43.9 41.9 58.0 54.0 57.7 46.0 75.3 36.8 41.1 60.0 45.7 59.7 46.1 49.1 43.1 204.0 61.9 59.9 44.7 50.6 53.1 63.7 36.6 56.6 59.5 49.4 236.6 56.5 55.5 53.4 56.0 111.6 147.4 66.0 57.9 71.3 55.9 76.0 58.2 74.0 134.5 106.7 191.4 113.4 124.5 52.2 80.4 123.7 152.7 122.9 189.0 122.6 34.7 96.7 151.2 58.4 200.6 69.7 166.5 31.8 74.4 71.5 125.9 65.7 59.2 80.4 105.6 194.9 67.7 83.0 61.1 146.1 190.4 128.3 113.4 137.9 117.7 120.2 140.2 77.7 102.5 118.5 85.5 71.9 235.0 127.3 50.8 118.1 73.0 72.4 104.2 65.4 35.8 136.3 91.2 225.3 129.8 49.1 169.9 101.2 76.0 111.7 72.2 84.9 120.8 64.5 96.3 72.8 77.7 131.9 84.6 84.6 73.1 31.4 84.8 110.9 61.2 108.1 102.1 51.8 53.0 60.8 57.9 53.8 56.3 58.0 54.0 60.0 50.6 56.6 56.0 50.7 38.5 28.2 10.4 52.1 56.7 60.2 103.8 48.9 37.9 38.5 38.2 186.0 52.9 49.5 23.9 33.3 133.9 71.3 81.7 156.5 88.5 59.3 28.2 36.0 53.7 50.7 41.6 7.0 102.1 86.3 49.2 37.2 35.9 48.2 54.1 41.7 55.4 97.6 13.5 7.6 68.4 71.2 57.7 60.9 115.1 45.1 51.7 69.4 10.3 78.7 49.3 56.7 6.6 8.9 70.8 72.5 47.4 38.1 37.5 121.7 174.9 33.4 33.4 78.9 50.0 64.1 52.8 55.3 48.4 60.0 108.5 49.1 63.4 113.7 54.3 IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 357.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" 13.7 17.2 8.1 11.8 8.2 14.5 14.2 11.1 10.0 10.5 11.2 14.1 16.9 11.2 10.9 12.0 9.0 10.2 17.0 8.2 9.1 31.4 19.5 12.3 11.4 8.8 8.9 11.6 13.7 19.2 15.5 10.9 9.0 13.9 13.0 14.1 15.0 7.9 31.1 13.8 15.7 9.5 8.0 11.1 15.9 9.3 8.9 11.1 15.9 21.7 10.6 13.9 11.0 8.9 27.1 15.3 22.9 20.5 30.5 33.8 15.9 62.7 30.5 30.6 32.2 12.5 22.7 26.5 19.3 28.1 25.0 32.3 21.8 22.1 33.2 43.5 19.5 23.3 23.0 38.2 32.5 70.5 33.2 26.8 27.7 27.6 20.6 28.9 26.7 23.7 19.4 39.7 33.0 15.0 25.1 33.7 11.6 11.5 18.4 24.7 35.9 37.9 31.2 26.0 26.4 29.4 21.5 18.1 38.8 16.4 18.0 40.1 38.7 45.2 23.3 22.0 34.7 56.9 66.4 27.9 35.3 44.4 37.2 15.9 17.2 16.1 25.0 16.6 22.2 18.9 21.1 21.5 16.6 20.9 19.6 20.8 1.9 17.3 17.5 34.5 23.6 19.3 8.1 8.2 11.1 10.0 8.2 9.1 8.8 8.9 9.0 8.0 8.9 8.9 80.8 86.6 51.8 7.8 58.9 0.0 64.6 0.0 73.4 48.0 96.0 51.4 63.1 97.2 19.2 51.5 8.4 104.9 61.3 35.6 140.8 124.3 18.4 49.5 47.7 70.8 37.6 51.3 15.7 138.9 126.3 76.2 57.6 55.6 13.9 40.0 83.6 138.8 108.9 40.4 17.4 69.1 0.0 63.6 0.0 13.3 84.8 54.8 0.0 12.2 79.4 69.6 86.5 16.1 19.1 139.3 50.1 48.5 158.8 117.3 125.0 357.0 26.2 48.0 52.6 40.4 61.6 163.3 158.9 88.1 0.0 177.2 54.4 36.7 62.2 109.4 IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" 41.3 82.4 30.3 34.9 31.8 40.3 36.5 33.1 39.0 30.2 41.9 57.4 57.4 35.0 27.6 43.4 30.9 27.1 174.8 31.9 34.5 80.9 65.0 32.5 44.3 35.3 34.2 28.1 48.5 90.2 36.0 36.7 35.1 29.4 58.1 42.4 37.9 35.1 200.9 38.0 46.6 38.9 29.8 44.8 56.0 49.2 32.6 52.3 35.5 288.9 47.1 41.5 33.8 32.8 115.6 111.2 99.2 45.6 93.7 88.3 101.5 80.5 85.6 108.0 98.7 160.7 89.1 175.7 78.9 87.7 87.7 83.4 128.9 118.4 131.8 71.4 105.9 139.0 65.6 192.0 95.7 135.9 91.1 100.6 84.0 101.7 119.5 67.2 124.7 99.7 138.4 96.7 105.1 99.0 135.6 140.8 117.8 175.1 88.2 89.9 211.2 158.7 122.5 128.3 119.3 89.0 82.9 124.0 126.3 77.4 70.7 94.6 93.6 76.0 83.6 112.0 101.8 76.6 104.1 119.9 86.9 158.8 94.4 12.1 29.2 12.2 23.5 34.0 20.7 15.9 20.6 19.3 32.9 13.7 18.3 22.3 3.8 20.8 33.2 17.2 23.2 25.4 30.3 31.8 33.1 39.0 31.9 34.5 35.3 34.2 35.1 29.8 32.6 32.8 29.3 54.5 49.2 31.3 42.1 23.3 34.9 51.6 30.1 40.9 21.6 19.7 223.0 24.3 57.3 40.5 33.3 94.9 49.6 57.9 133.1 59.9 152.4 26.5 34.0 38.3 56.0 76.1 41.6 52.8 73.9 36.3 39.8 26.8 48.0 55.6 35.7 64.2 70.9 23.5 46.5 46.2 38.7 49.4 28.3 158.9 27.7 48.9 17.8 26.2 80.6 30.2 52.5 29.1 44.1 43.3 36.3 36.9 56.4 28.6 59.8 92.6 41.8 42.5 6.6 39.7 58.2 100.7 54.6 41.1 24.9 98.5 45.6 118.6 68.0 33.6 IPP KLHL27 ENSG00000197429 "Intracisternal A particle-promoted polypeptide" Q9Y573 1 45694324-45750653 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075545 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA075545: " "unprognostic (8.45e-3)" "unprognostic (1.35e-1)" "prognostic favorable (9.11e-4)" "unprognostic (1.63e-1)" "unprognostic (2.87e-1)" "unprognostic (5.84e-3)" "prognostic unfavorable (2.27e-4)" "unprognostic (2.99e-1)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.77e-1)" "unprognostic (7.03e-2)" "prognostic favorable (1.11e-4)" "unprognostic (2.68e-2)" "unprognostic (6.44e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-1)" 5.5 4.4 3.2 3.8 4.7 3.4 6.1 3.9 2.9 4.8 3.7 5.6 4.9 6.5 5.3 6.3 6.5 5.0 7.0 2.6 4.1 7.1 6.8 4.3 4.4 3.5 3.9 7.5 6.6 9.5 2.2 4.0 3.7 7.1 5.7 7.4 5.7 6.4 14.3 5.0 5.3 5.6 3.7 3.8 5.0 10.2 3.6 6.6 9.7 9.0 4.9 3.8 2.8 4.9 9.6 9.1 8.0 11.8 9.8 18.2 6.2 9.9 7.1 6.9 7.0 5.6 6.8 5.2 10.1 12.3 7.9 6.7 8.8 7.3 9.9 12.2 5.2 7.3 7.7 6.9 9.8 2.1 6.2 15.5 8.3 15.0 8.1 8.0 6.8 9.4 9.0 10.3 12.2 6.4 7.3 0.4 4.8 7.0 4.9 3.1 14.7 4.3 5.7 10.4 11.5 7.5 19.1 10.3 9.5 9.1 10.0 1.8 7.9 7.5 9.2 5.3 7.9 8.3 10.4 9.2 12.0 3.1 11.9 4.1 0.6 3.5 4.6 0.4 3.4 3.1 2.7 3.7 0.7 2.6 3.4 4.0 2.6 3.7 0.8 0.6 4.7 2.5 3.2 4.7 3.9 2.9 2.6 4.1 3.5 3.9 3.7 3.7 3.6 4.9 7.6 12.8 10.0 11.1 7.9 2.5 5.6 7.6 6.8 12.4 6.5 4.8 18.8 5.7 8.1 5.5 12.5 7.8 4.7 10.1 3.9 6.5 26.0 10.7 10.1 5.2 5.4 3.0 5.4 7.3 6.9 9.6 9.7 6.7 12.7 15.9 3.3 5.9 1.4 18.5 7.1 6.8 6.1 1.3 1.1 7.6 7.2 2.8 1.8 4.7 3.4 19.0 18.6 6.0 11.9 5.8 4.6 6.4 7.4 3.9 9.5 8.4 10.1 16.8 0.0 14.0 9.3 40.8 14.7 6.7 4.7 7.7 8.4 23.5 5.8 4.9 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Supported "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: AB_2680205" "unprognostic (4.18e-2)" "unprognostic (3.90e-2)" "prognostic favorable (7.88e-4)" "unprognostic (7.04e-2)" "unprognostic (7.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.20e-2)" "unprognostic (6.01e-2)" "unprognostic (4.33e-1)" "unprognostic (2.43e-2)" "unprognostic (4.49e-3)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (4.97e-3)" 18.4 8.2 4.9 11.5 5.8 21.5 22.3 7.9 6.5 15.4 8.6 21.1 19.6 11.3 13.0 23.8 14.6 13.3 38.3 5.5 5.9 12.8 10.8 13.4 12.2 9.1 7.7 14.2 11.2 11.0 9.8 12.0 10.0 17.4 22.6 12.9 17.5 15.6 29.5 19.0 17.7 14.5 7.8 9.4 12.8 12.9 6.9 14.7 13.7 36.7 14.4 15.6 18.7 6.9 46.4 32.4 34.5 11.9 44.0 58.0 28.2 68.6 61.4 44.1 44.5 23.4 33.2 30.1 28.6 69.0 62.3 30.3 30.6 32.3 52.9 15.4 18.2 35.3 30.2 21.7 53.2 12.3 25.1 44.8 38.5 40.2 33.2 26.9 37.8 29.6 37.8 23.0 50.7 12.4 48.2 21.6 16.8 35.8 17.0 18.6 39.8 11.2 45.0 26.1 8.8 11.4 52.7 23.1 35.8 30.8 17.8 14.2 42.2 48.5 28.2 94.1 37.6 6.6 12.9 39.1 33.9 21.8 35.8 0.7 0.5 1.2 1.0 0.7 1.0 0.6 1.0 1.0 0.3 0.3 0.6 0.9 0.5 0.2 0.9 1.0 1.1 0.4 4.9 5.8 7.9 6.5 5.5 5.9 9.1 7.7 10.0 7.8 6.9 6.9 19.5 32.1 18.5 18.6 8.9 74.4 36.4 26.0 31.9 13.7 20.4 12.7 61.1 5.7 24.2 27.6 25.0 9.4 23.3 53.8 13.7 17.6 6.5 12.8 12.7 16.8 10.2 20.2 14.3 27.2 17.6 32.5 8.2 17.9 20.3 10.9 12.5 9.0 9.3 3.3 12.9 16.0 18.3 9.3 18.5 5.2 30.7 12.9 30.2 36.5 8.5 8.1 18.6 17.1 13.6 36.6 21.6 55.7 17.1 52.6 25.8 10.4 17.4 19.6 6.6 21.6 26.2 35.6 26.4 41.6 54.7 11.2 19.8 14.4 17.7 46.0 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KLHDC2 "HCLP-1, LCP" ENSG00000165516 "Kelch domain containing 2" Q9Y2U9 14 49768130-49786385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000628 Approved Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nuclear bodies" "HPA000628: AB_2666051" "unprognostic (2.65e-1)" "unprognostic (8.29e-2)" "unprognostic (1.30e-2)" "unprognostic (9.01e-2)" "unprognostic (2.57e-2)" "unprognostic (5.52e-3)" "unprognostic (4.54e-2)" "unprognostic (9.72e-3)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (4.81e-3)" "unprognostic (6.77e-3)" "prognostic favorable (2.75e-10)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (1.32e-2)" "unprognostic (9.34e-2)" 21.5 22.3 12.8 8.6 13.3 10.1 19.6 13.7 16.1 18.8 15.0 23.8 18.4 20.7 14.8 15.0 17.0 13.8 38.0 14.4 14.0 34.1 49.1 14.5 10.9 12.4 12.3 25.1 30.3 16.8 17.7 12.7 13.9 18.5 18.0 23.9 20.1 20.1 53.0 18.8 21.6 14.1 13.3 12.3 24.4 23.3 12.6 15.2 28.2 38.2 10.5 22.3 16.2 14.9 14.7 12.2 22.5 11.0 31.7 27.5 23.7 15.0 28.8 18.8 19.0 7.1 19.6 29.1 20.4 27.4 10.8 12.8 13.9 13.9 15.9 20.1 14.7 9.1 8.6 17.0 23.1 19.6 7.8 28.6 23.5 8.6 16.9 23.1 17.4 24.6 11.8 21.5 15.1 17.3 20.1 8.6 16.6 17.0 34.8 15.3 24.0 18.1 8.6 31.2 27.4 22.0 25.1 46.4 17.1 17.2 17.8 7.4 14.9 17.2 13.3 13.7 7.8 29.0 19.7 17.1 9.7 10.0 9.2 12.3 9.1 19.9 11.1 6.1 13.8 18.2 16.8 17.4 9.0 19.0 23.5 15.8 8.4 16.8 5.8 6.8 18.0 12.3 12.8 13.3 13.7 16.1 14.4 14.0 12.4 12.3 13.9 13.3 12.6 14.9 40.6 41.7 52.4 30.3 42.1 48.9 53.5 64.8 53.5 65.1 48.6 40.9 9.3 77.2 53.9 47.8 50.1 102.5 40.7 68.9 107.6 59.8 96.8 44.8 41.9 36.4 57.2 47.8 30.6 85.8 68.6 51.2 67.2 38.7 30.4 62.8 45.3 91.8 33.2 65.6 35.4 75.3 63.1 28.7 33.6 27.1 81.4 26.5 39.2 18.7 36.3 73.9 54.6 28.1 33.1 54.8 78.9 77.5 74.5 53.9 143.9 170.1 27.8 98.1 65.7 46.3 90.5 238.7 93.2 42.7 66.3 82.4 44.9 54.7 78.9 55.5 KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 59.1;Skeletal myocytes: 82.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "RH-30: 34.7;U-2197: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" 7.3 13.5 10.3 9.5 22.3 4.1 7.6 7.4 10.8 9.1 5.6 13.1 6.6 6.7 8.7 37.2 10.9 4.0 22.7 12.7 7.6 9.0 2.4 11.9 2.9 8.2 9.8 22.2 4.6 48.2 6.5 6.1 8.0 9.1 11.3 4.0 28.3 9.8 28.7 36.3 11.1 6.2 5.6 9.1 9.4 12.5 12.9 22.4 9.5 42.6 16.4 9.2 13.7 8.3 5.2 3.6 11.8 6.2 3.9 11.9 9.9 1.4 12.0 3.8 5.7 16.5 2.4 0.1 4.5 5.6 9.6 24.7 24.6 9.9 4.1 6.2 15.5 1.4 1.7 15.6 4.1 0.1 1.3 11.4 19.7 4.3 2.4 1.6 0.6 10.1 5.4 0.3 4.8 4.4 0.1 1.7 0.5 34.0 2.5 0.8 34.7 0.3 4.1 9.7 23.6 13.1 14.2 5.0 18.3 3.9 18.5 0.9 0.4 15.7 4.8 59.3 1.7 1.2 0.4 0.2 10.0 2.2 18.5 1.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 4.6 0.3 0.2 0.6 0.1 0.1 10.3 22.3 7.4 10.8 12.7 7.6 8.2 9.8 8.0 5.6 12.9 8.3 2.0 16.0 18.4 59.1 0.3 15.3 14.0 14.1 7.4 4.4 5.7 6.1 23.9 14.3 18.3 7.3 0.0 15.5 0.3 3.9 1.9 5.4 3.2 6.2 19.7 3.9 0.0 17.2 10.3 4.2 1.8 24.4 8.6 8.0 19.0 5.9 5.3 2.6 2.6 0.0 2.7 19.4 4.1 24.1 6.8 10.8 17.7 2.5 0.0 15.9 2.7 22.2 2.1 10.6 6.3 3.0 9.5 10.5 0.1 10.9 2.2 4.7 18.4 3.4 13.1 82.2 7.9 8.1 6.0 26.3 19.5 5.3 2.3 33.5 10.2 10.5 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 LARP4 PP13296 ENSG00000161813 "La ribonucleoprotein 4" Q71RC2 12 50392383-50480004 "Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039306, HPA039673" Approved Enhanced "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoli fibrillar center" "HPA039306: AB_10805362, HPA039673: AB_10795110" "unprognostic (4.41e-3)" "unprognostic (4.11e-2)" "unprognostic (2.01e-2)" "unprognostic (8.50e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (9.93e-3)" "unprognostic (9.08e-2)" "unprognostic (8.94e-2)" "unprognostic (8.51e-3)" "unprognostic (1.91e-2)" "unprognostic (3.14e-1)" "unprognostic (9.06e-2)" "unprognostic (3.99e-3)" 17.4 27.7 9.5 16.2 12.6 14.0 14.6 16.4 10.8 14.1 23.8 15.3 16.7 10.5 11.7 18.9 9.3 12.9 16.3 8.8 13.9 29.0 62.1 13.5 15.6 13.2 14.4 9.4 16.5 21.8 8.8 18.3 14.0 13.9 14.4 20.3 15.9 11.3 26.4 11.2 13.1 11.7 12.2 12.5 17.2 14.9 13.0 15.9 20.0 37.0 15.5 21.5 9.0 17.3 43.9 61.0 40.1 29.6 36.6 30.2 67.9 52.9 31.5 51.3 40.8 120.5 50.2 102.9 63.9 33.2 47.5 41.1 88.2 36.1 67.3 64.3 35.9 83.9 56.1 43.6 34.0 93.9 47.5 27.6 33.9 60.9 65.1 33.9 45.9 37.2 122.8 47.4 48.0 39.3 77.7 31.6 58.2 28.5 52.9 56.6 63.6 61.0 27.8 65.1 47.2 27.7 94.0 48.3 54.9 37.0 42.1 37.4 66.9 34.0 50.2 39.7 50.4 45.9 134.7 90.3 47.0 37.9 28.9 8.2 8.7 6.0 8.1 9.6 7.5 8.6 7.0 4.5 11.7 8.6 8.2 6.7 4.4 8.2 12.1 10.0 7.6 7.7 9.5 12.6 16.4 10.8 8.8 13.9 13.2 14.4 14.0 12.2 13.0 17.3 35.9 48.1 44.7 31.0 26.8 71.0 33.8 23.1 59.7 41.0 34.0 25.1 47.8 22.8 27.7 29.5 87.6 27.4 22.0 29.1 9.8 19.7 8.6 52.9 50.4 28.6 24.0 33.0 38.9 24.0 17.3 31.0 38.7 57.5 19.7 27.9 21.0 129.0 27.3 18.5 45.5 25.8 20.3 33.0 26.6 25.4 14.9 23.0 26.6 24.4 27.6 18.4 13.4 26.7 40.4 27.0 16.1 19.2 56.4 44.3 20.3 54.7 33.0 54.0 6.6 42.2 36.8 37.4 42.5 52.2 74.3 34.2 22.0 34.4 27.5 33.2 LARP7 "DKFZP564K112, HDCMA18P, PIP7S" ENSG00000174720 "La ribonucleoprotein 7, transcriptional regulator" Q4G0J3 4 112637107-112657592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" RNA-binding "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026842, HPA027930" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA026842: AB_10611116, HPA027930: AB_10601233" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (5.72e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (1.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 37.2 31.6 26.3 32.8 28.3 44.6 35.7 28.6 34.6 28.0 28.0 36.2 33.8 33.3 29.8 31.7 25.8 30.5 59.6 24.9 33.5 40.2 44.1 28.1 44.9 30.2 30.2 34.2 18.3 29.9 20.1 34.1 31.0 32.1 36.7 31.5 23.2 27.2 46.6 30.6 33.2 29.5 28.3 36.9 31.5 24.6 29.1 42.2 38.7 45.3 40.3 33.0 21.8 30.8 42.9 34.9 77.7 44.3 50.7 61.6 44.0 55.3 40.6 45.3 42.0 27.9 62.0 95.4 43.7 46.9 42.2 29.6 75.1 45.2 60.2 86.8 52.1 56.4 35.2 41.9 41.0 131.6 84.6 49.3 50.7 40.4 25.1 62.6 40.4 47.6 71.4 51.1 55.3 35.2 107.4 56.7 182.2 67.5 28.2 62.9 66.2 44.3 68.8 44.8 46.5 64.4 32.0 83.4 55.4 131.4 35.1 61.0 43.7 42.4 49.5 47.7 57.6 34.7 62.5 97.6 57.7 52.4 49.2 70.1 28.1 49.9 32.8 43.1 30.3 48.1 33.9 34.2 25.3 47.4 32.3 31.3 33.2 38.7 60.7 64.0 37.9 20.8 26.3 28.3 28.6 34.6 24.9 33.5 30.2 30.2 31.0 28.3 29.1 30.8 66.1 96.1 79.2 45.1 68.8 24.9 66.5 102.6 34.1 61.3 48.3 50.4 113.2 95.8 91.6 47.8 29.2 79.0 88.7 83.2 111.6 69.3 17.6 78.7 70.5 63.2 38.9 43.6 18.0 64.4 70.2 60.6 32.1 58.8 104.4 51.5 81.4 160.9 70.4 58.9 19.9 79.7 61.1 93.7 27.1 14.9 94.4 67.2 24.9 32.8 96.0 107.1 107.1 20.6 43.1 62.0 85.6 100.1 39.1 38.8 73.1 117.0 109.8 54.1 118.3 74.5 68.3 83.5 87.8 33.3 20.9 100.4 65.9 74.2 75.6 47.9 LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 248.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1682.7;Urothelial cells: 435.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 177 "amygdala: 12.6;basal ganglia: 19.9;cerebral cortex: 25.6;hippocampal formation: 14.9;white matter: 15.4" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 343.4;fHDF/TERT166: 568.2;LHCN-M2: 525.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 20.8;basal ganglia: 32.8;cerebral cortex: 26.6;hippocampal formation: 33.8" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" 4.4 5.3 12.6 10.6 19.9 4.1 9.3 0.0 25.6 12.8 4.8 47.4 66.3 5.7 12.1 153.7 14.5 43.3 248.8 14.9 0.0 44.1 61.9 178.7 11.0 0.0 0.0 18.6 25.5 11.8 6.4 41.3 0.0 27.3 32.5 4.8 32.4 15.1 143.5 21.1 79.7 7.9 0.0 5.0 62.7 18.2 0.0 56.8 53.5 99.5 37.1 24.5 38.4 15.4 77.8 43.6 1.7 1.3 86.5 61.4 14.9 343.4 168.3 85.4 91.6 107.4 97.8 6.6 25.7 568.2 21.2 73.5 18.9 16.6 97.8 105.4 4.5 47.8 229.2 102.2 25.0 15.3 24.0 42.0 31.1 37.0 42.3 207.9 36.2 14.7 1.7 0.5 525.9 30.4 11.6 6.4 2.2 119.6 65.0 7.2 159.5 1.6 36.0 18.1 5.4 11.6 62.2 10.8 13.8 8.6 14.0 11.3 55.6 208.7 38.7 25.4 84.9 22.6 18.4 27.8 61.6 17.0 97.0 4.5 0.2 2.7 0.6 0.5 0.9 1.1 3.2 1.0 0.4 2.3 13.6 8.6 0.1 0.6 0.4 1.1 1.4 2.6 12.6 19.9 0.0 25.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 15.4 1.5 1682.7 279.7 22.2 4.3 24.0 74.7 59.9 72.8 6.8 10.5 13.2 362.6 51.5 317.2 62.5 2.1 45.5 3.6 378.5 15.6 81.5 6.2 92.0 19.0 9.0 71.2 3.6 162.3 37.8 8.7 38.0 276.3 244.4 20.3 9.5 6.1 72.7 6.0 6.7 82.5 96.6 67.1 3.5 4.4 8.0 42.0 6.4 16.0 39.4 2.8 1.9 3.1 30.7 48.4 228.8 351.2 42.5 2.1 344.9 213.8 15.5 199.5 10.5 13.1 27.2 18.1 11.2 6.3 100.9 45.3 17.0 12.9 2.5 75.2 435.7 LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" 32.2 33.2 30.1 23.8 31.3 49.6 41.6 39.3 35.4 23.9 49.2 50.6 33.4 32.5 28.4 28.4 27.6 18.2 47.0 30.8 31.8 63.5 48.3 19.6 31.2 33.0 30.4 34.1 30.4 48.7 19.2 27.2 35.2 27.7 48.9 40.4 27.8 25.3 100.9 30.2 30.3 27.6 30.2 24.3 27.1 33.2 32.1 29.3 31.2 93.5 31.7 27.0 22.5 36.3 127.8 101.9 62.3 80.0 58.1 79.9 108.0 82.7 59.4 88.0 67.3 164.4 65.7 181.7 78.4 50.8 58.8 105.2 118.8 86.3 116.8 110.2 75.2 164.2 76.5 217.9 85.5 239.9 71.4 77.3 73.8 81.6 130.4 49.2 71.2 53.6 246.5 71.5 75.8 68.5 126.8 273.7 104.0 123.8 71.8 139.7 140.7 147.6 95.3 115.3 111.0 107.3 93.6 120.6 154.5 79.2 90.1 140.6 62.6 63.2 86.4 66.9 89.2 72.5 87.4 156.2 60.0 144.1 55.6 10.5 16.5 2.9 13.3 16.2 25.5 22.5 18.0 17.9 23.5 24.5 24.8 21.9 1.2 20.3 18.9 9.6 16.3 20.2 30.1 31.3 39.3 35.4 30.8 31.8 33.0 30.4 35.2 30.2 32.1 36.3 29.2 22.4 34.1 56.8 46.2 46.3 27.2 34.6 46.1 66.4 37.6 30.4 97.2 32.9 35.4 46.0 31.3 37.1 22.5 33.1 21.5 25.6 5.3 31.2 48.2 30.4 27.5 58.4 91.6 17.7 23.6 32.4 40.2 40.1 29.2 51.0 22.1 55.1 25.2 65.6 96.5 49.2 20.3 38.8 25.9 6.3 25.1 28.9 21.4 38.4 36.8 24.5 23.7 55.3 94.9 20.0 33.0 23.7 34.4 31.9 36.6 62.3 25.8 57.0 13.1 45.8 32.6 27.2 33.3 53.9 44.3 33.2 32.2 63.7 76.0 31.9 LYPLA1 "APT-1, LPL1" ENSG00000120992 "Lysophospholipase 1" O75608 8 54046367-54102017 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 787.7;Late spermatids: 796.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050941, HPA063151" Enhanced Approved Nucleoplasm,Cytosol NA NA 330000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA050941: AB_2681284, HPA063151: " "unprognostic (2.62e-2)" "unprognostic (1.28e-2)" "unprognostic (3.25e-3)" "unprognostic (9.42e-2)" "unprognostic (9.48e-2)" "unprognostic (3.56e-1)" "unprognostic (9.58e-2)" "unprognostic (2.05e-2)" "unprognostic (6.52e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.58e-1)" "unprognostic (2.15e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (2.56e-3)" 25.8 30.3 8.8 31.8 7.6 43.6 45.0 10.5 12.7 23.3 14.7 42.6 44.4 19.7 16.1 55.0 22.9 25.9 40.9 7.9 10.8 63.4 83.5 25.9 49.0 9.9 9.5 11.7 23.8 40.8 8.8 50.4 9.1 35.0 42.1 45.9 35.5 15.0 54.5 41.4 42.8 24.3 9.7 30.2 35.4 65.1 10.3 28.8 28.4 70.7 52.0 63.1 27.5 10.0 124.0 69.3 85.9 78.7 31.0 49.4 109.8 71.7 41.6 65.0 61.1 53.2 116.7 214.8 83.6 47.2 70.5 80.7 122.8 119.9 89.8 78.9 70.0 148.8 37.9 80.0 50.8 91.4 196.1 44.6 103.8 50.8 114.0 55.6 171.6 91.6 154.5 63.4 91.3 32.7 141.1 69.9 129.3 206.3 31.5 85.3 45.2 99.3 100.2 163.6 45.2 77.6 50.1 93.6 113.4 81.0 137.0 81.7 83.4 39.0 56.9 68.7 67.8 89.3 143.8 194.0 52.9 97.1 78.7 93.7 80.7 111.1 44.8 79.6 44.6 73.0 42.2 43.5 92.3 64.4 42.1 41.1 49.3 69.6 108.2 59.7 75.5 98.3 8.8 7.6 10.5 12.7 7.9 10.8 9.9 9.5 9.1 9.7 10.3 10.0 60.4 28.9 53.3 19.9 83.8 61.7 94.8 96.6 82.6 34.9 103.8 64.0 70.8 57.2 71.8 62.5 52.1 199.7 74.5 70.4 303.3 82.8 787.7 86.6 34.7 69.3 57.5 50.0 30.0 89.0 318.3 36.4 74.9 96.3 49.5 31.5 81.4 120.1 121.0 18.5 43.7 77.3 99.7 108.4 83.3 796.2 28.3 82.6 74.7 25.3 102.1 36.9 69.0 20.6 9.8 127.4 63.7 23.0 104.5 171.0 91.6 194.3 62.9 70.3 46.0 24.5 43.1 92.1 239.1 118.2 81.1 334.2 57.0 94.0 90.2 229.7 LYRM2 DJ122O8.2 ENSG00000083099 "LYR motif containing 2" Q9NU23 6 89568144-89638749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063932 Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA063932: AB_2685155" "unprognostic (3.23e-2)" "unprognostic (1.47e-1)" "unprognostic (8.52e-3)" "unprognostic (8.49e-2)" "unprognostic (4.27e-2)" "unprognostic (6.26e-2)" "prognostic unfavorable (2.58e-8)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "unprognostic (3.29e-3)" "unprognostic (8.07e-3)" "unprognostic (3.63e-2)" "unprognostic (7.98e-2)" "unprognostic (3.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.23e-2)" "unprognostic (5.64e-2)" 10.7 15.9 11.6 10.3 12.3 14.8 14.1 11.2 12.3 9.4 9.1 13.7 8.6 11.1 14.3 12.3 13.4 10.2 17.4 12.5 12.4 17.4 12.4 10.1 12.8 11.2 11.9 9.9 10.5 22.5 10.7 13.9 11.1 13.2 16.1 9.0 9.8 8.6 21.3 6.2 9.5 11.9 12.5 9.0 13.0 8.7 12.5 9.2 25.2 16.9 10.9 10.7 6.6 12.7 18.4 9.6 32.1 19.7 16.0 24.0 12.8 31.3 22.2 24.0 23.8 8.6 9.6 25.1 29.5 29.6 35.7 16.5 20.6 29.7 30.8 32.0 36.5 39.8 9.9 7.3 24.0 42.6 29.7 29.7 28.2 27.2 36.5 19.4 18.8 27.0 41.8 32.0 27.9 16.5 10.0 15.3 7.6 14.9 12.5 20.7 40.1 18.9 27.2 18.1 35.7 24.2 18.3 11.1 31.1 14.6 15.8 43.0 30.2 15.0 13.2 27.4 44.0 22.9 35.1 13.0 31.6 30.3 28.9 16.4 21.0 14.3 21.5 24.8 23.1 32.6 24.0 28.4 19.7 30.9 26.8 25.1 6.0 27.3 33.9 26.1 24.2 14.8 11.6 12.3 11.2 12.3 12.5 12.4 11.2 11.9 11.1 12.5 12.5 12.7 37.1 41.7 50.3 11.8 47.6 11.9 29.0 43.1 29.0 27.0 37.6 45.7 87.5 27.1 48.3 27.6 16.7 87.6 33.9 31.3 93.9 40.1 66.0 86.2 56.6 30.7 40.7 35.3 17.6 49.4 32.9 35.6 37.2 55.8 32.9 33.9 24.7 27.1 57.8 25.2 19.7 43.4 44.7 35.1 12.9 18.7 30.7 39.9 30.2 15.9 44.8 100.6 44.3 13.0 26.4 40.1 32.8 27.1 30.9 25.9 29.3 68.8 70.6 45.3 52.6 39.2 41.1 57.0 31.6 43.3 16.2 72.4 37.5 81.8 39.8 26.2 LYSMD3 FLJ13542 ENSG00000176018 "LysM domain containing 3" Q7Z3D4 5 90515611-90529584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018024 Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA018024: AB_2138525" "unprognostic (4.50e-2)" "unprognostic (1.85e-2)" "prognostic favorable (3.83e-4)" "unprognostic (5.59e-2)" "unprognostic (5.61e-2)" "unprognostic (9.80e-3)" "unprognostic (3.99e-2)" "unprognostic (4.66e-2)" "unprognostic (6.23e-2)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (2.02e-1)" "prognostic favorable (9.25e-4)" "unprognostic (1.81e-1)" "unprognostic (8.48e-2)" "unprognostic (4.97e-3)" "unprognostic (9.46e-2)" 10.4 14.3 4.2 12.6 4.5 11.7 11.6 7.9 6.3 14.2 10.8 12.3 12.8 12.1 5.2 10.2 7.4 13.4 12.0 4.4 5.4 13.6 24.1 13.3 12.6 4.3 5.7 15.0 9.0 18.2 7.5 17.1 4.5 13.1 11.3 11.4 11.5 10.2 9.7 6.3 11.9 11.0 4.4 11.4 9.7 6.0 5.2 12.5 18.0 16.3 12.6 10.6 5.5 6.3 17.5 11.6 14.5 15.4 22.2 22.4 14.3 27.3 29.5 18.6 30.2 9.9 17.6 21.6 11.5 24.1 29.1 8.7 22.5 26.6 36.3 16.0 14.2 16.4 14.2 16.2 23.0 13.9 26.5 16.6 18.4 17.1 28.5 19.9 27.1 13.6 15.9 32.1 21.1 15.5 16.1 8.1 7.1 4.4 19.4 14.8 24.5 31.0 20.5 11.9 4.4 8.8 16.2 12.1 22.6 11.4 14.0 12.9 34.1 11.2 15.8 24.8 20.1 36.2 24.7 18.2 18.9 23.3 17.9 53.7 11.5 18.1 9.2 14.4 14.7 9.6 10.5 11.4 11.2 8.4 14.1 12.3 17.2 18.5 15.3 5.3 12.7 11.4 4.2 4.5 7.9 6.3 4.4 5.4 4.3 5.7 4.5 4.4 5.2 6.3 18.6 35.3 27.1 8.8 22.0 14.3 10.1 9.7 11.4 10.3 20.3 14.6 25.0 7.2 18.0 12.9 4.2 10.2 27.3 16.6 1.9 7.1 1.2 17.1 21.7 15.7 21.6 12.6 13.4 8.1 10.8 20.0 15.8 24.6 26.0 10.6 21.4 32.9 8.7 20.2 13.5 17.3 10.2 16.7 23.5 1.9 16.8 19.2 7.2 10.3 13.5 21.5 11.3 14.6 18.8 7.7 9.2 13.2 41.5 16.4 14.5 12.9 14.5 13.7 19.7 15.9 16.7 7.5 5.5 13.4 16.6 14.0 21.5 10.9 12.0 13.0 MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.0;Distal tubular cells: 37.2;Ductal cells: 31.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 33.8;Proximal tubular cells: 84.2;Syncytiotrophoblasts: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" 11.1 16.1 7.0 8.3 7.2 18.7 11.3 10.1 8.4 7.3 6.5 14.4 21.1 7.8 7.4 11.7 9.0 8.1 16.6 7.5 6.5 31.1 46.2 7.4 8.8 6.7 6.5 7.5 10.3 12.2 5.8 9.3 7.3 9.1 13.1 7.2 9.6 9.0 22.2 9.7 16.8 7.5 7.1 8.5 12.6 4.9 6.8 9.3 9.7 16.8 10.4 9.2 8.2 8.6 23.9 21.8 19.3 15.2 16.8 16.9 44.5 21.1 20.2 30.7 29.3 59.5 21.0 15.7 29.6 14.6 25.4 25.8 28.7 22.7 28.8 24.7 32.9 26.4 18.5 54.7 22.6 36.7 18.0 18.1 18.3 20.3 21.9 17.6 19.7 29.9 35.2 19.8 20.2 31.4 27.8 34.0 24.7 25.2 51.6 26.4 22.9 31.6 36.6 30.5 21.8 15.1 21.7 24.4 40.1 24.3 21.6 22.1 17.6 17.9 25.6 15.6 23.7 18.8 23.6 33.7 27.0 21.1 18.7 9.9 12.9 9.4 10.8 12.8 13.3 13.8 10.6 7.7 16.8 14.1 10.0 8.6 2.0 8.9 12.6 13.5 13.9 8.2 7.0 7.2 10.1 8.4 7.5 6.5 6.7 6.5 7.3 7.1 6.8 8.6 11.7 9.6 14.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.8 14.1 0.0 0.0 5.0 3.7 0.0 30.0 7.0 0.0 37.2 31.4 0.0 10.0 10.2 6.1 0.0 0.0 0.0 28.0 33.8 6.2 0.0 11.9 3.8 12.2 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 21.2 0.0 0.0 1.3 0.0 0.0 84.2 5.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 32.0 4.0 18.3 0.0 0.0 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542703-67807117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Astrocytes: 119.5;Early spermatids: 138.1;Excitatory neurons: 201.4;Inhibitory neurons: 169.3;Late spermatids: 212.4;Microglial cells: 87.1;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 146.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favorable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 14.3 14.8 9.2 6.3 9.8 10.3 12.4 11.2 14.1 13.2 4.6 15.7 9.2 11.5 6.1 8.7 12.1 8.8 15.0 11.6 9.9 9.9 10.0 9.7 8.5 9.6 6.5 17.2 13.2 18.8 10.2 11.1 9.4 9.4 8.8 11.2 10.5 10.6 23.2 14.5 10.1 8.9 5.6 9.0 11.6 13.8 7.3 17.2 10.6 17.8 7.6 11.8 11.1 12.3 9.0 23.4 13.8 16.3 20.0 34.9 10.9 8.8 17.8 16.3 17.7 9.4 15.8 14.8 18.2 14.8 17.7 13.3 23.8 14.3 13.4 21.6 23.7 20.2 17.0 10.3 25.1 12.3 12.1 23.9 18.3 11.8 26.6 35.7 21.7 33.6 18.0 24.1 13.6 11.6 20.1 14.7 19.4 10.4 11.3 19.7 16.0 24.9 9.8 16.3 8.6 13.4 9.9 14.5 36.5 23.6 18.2 23.7 18.2 16.7 10.9 11.7 12.1 33.7 43.4 17.5 22.4 27.6 12.3 10.9 5.8 5.6 5.6 4.4 8.3 4.8 5.3 6.7 8.1 4.3 7.3 7.0 1.4 9.4 5.4 3.0 6.2 4.4 9.2 9.8 11.2 14.1 11.6 9.9 9.6 6.5 9.4 5.6 7.3 12.3 7.9 6.4 5.8 119.5 10.0 6.9 8.1 3.7 8.6 12.6 8.6 6.1 8.1 5.7 3.2 5.5 10.4 13.4 10.2 13.2 7.9 9.3 138.1 4.4 5.0 7.6 9.5 9.4 201.4 8.5 10.7 9.7 7.7 3.9 2.5 12.3 12.5 8.7 10.0 5.0 169.3 9.2 4.1 10.1 6.1 212.4 12.5 7.9 10.6 87.1 7.2 17.9 11.3 146.3 146.5 7.5 12.5 11.7 5.6 5.3 12.2 9.7 4.0 8.2 0.0 7.9 6.3 11.9 13.0 9.9 8.2 9.9 10.4 11.6 10.4 4.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437301 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 118.8;Excitatory neurons: 201.0;Inhibitory neurons: 198.3;Microglial cells: 144.3;Oligodendrocyte precursor cells: 160.4;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "AF22: 102.3;RT4: 97.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 15.8 17.1 11.6 6.7 12.5 10.5 16.6 21.6 16.7 15.0 15.3 15.5 13.2 17.2 13.4 10.2 13.6 14.7 19.3 14.2 11.2 24.5 15.1 13.3 6.1 9.9 10.0 20.2 12.2 25.3 12.2 27.4 10.0 16.9 13.0 28.0 10.8 14.0 30.9 16.4 14.3 14.5 11.3 11.6 26.6 21.3 10.2 8.1 24.4 22.2 6.1 18.3 11.4 14.4 25.6 15.6 102.3 16.3 16.3 32.4 28.0 22.1 28.3 21.6 18.3 13.3 12.6 5.5 24.3 15.3 22.1 13.6 39.0 19.7 32.6 6.3 16.0 9.2 10.8 30.9 42.3 4.0 14.5 29.3 19.0 28.1 30.1 22.6 18.8 5.0 12.1 9.9 29.2 13.9 9.0 6.0 30.7 24.0 23.4 9.9 33.3 4.2 28.3 97.3 18.2 20.7 12.9 20.7 58.8 32.0 13.9 5.6 15.4 16.7 19.7 15.0 12.1 15.1 9.3 1.9 20.5 6.6 19.0 0.7 0.1 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 11.6 12.5 21.6 16.7 14.2 11.2 9.9 10.0 10.0 11.3 10.2 14.4 36.2 3.2 8.4 118.8 8.1 17.6 17.9 11.0 16.5 24.7 14.1 12.3 38.2 21.5 16.5 22.0 25.0 13.1 4.1 12.5 19.6 10.3 45.1 22.3 19.9 20.6 9.6 4.6 201.0 12.4 6.7 18.2 25.5 59.4 2.5 15.6 14.3 18.6 9.7 6.7 198.3 13.9 2.0 10.9 20.6 103.0 20.8 14.4 5.4 144.3 4.4 13.2 3.1 160.4 129.2 17.5 5.7 17.7 14.3 18.6 14.0 11.9 19.5 37.9 19.7 18.7 17.6 22.6 19.8 11.8 19.2 10.4 5.9 17.4 10.6 30.2 MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 106.5;heart muscle: 256.3;skeletal muscle: 224.2;tongue: 284.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 226.6;Hofbauer cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.8;granulocytes: 126.3;monocytes: 341.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 15.3 43.3 18.0 29.8 19.6 106.5 15.8 19.2 19.2 15.0 21.3 19.7 30.2 11.3 10.3 49.6 15.1 12.1 256.3 18.0 19.7 40.0 18.7 28.2 21.7 23.6 20.5 14.2 36.2 47.2 23.5 13.9 22.5 18.4 20.0 4.7 27.7 12.6 224.2 53.4 24.2 15.9 21.6 25.3 27.6 9.2 21.1 42.0 41.2 284.3 24.2 20.3 22.2 21.6 99.6 30.3 12.4 35.9 18.4 45.7 27.9 23.8 33.7 35.7 30.3 47.1 90.2 39.8 23.5 79.5 88.5 34.6 85.9 92.7 31.9 88.3 22.3 209.5 40.6 43.5 36.8 152.1 106.4 36.9 57.0 83.1 112.2 35.6 31.9 70.2 59.7 25.4 76.1 40.5 65.3 153.3 46.4 34.6 127.0 28.5 29.9 60.1 165.5 56.2 23.0 16.5 21.3 58.9 27.7 20.6 37.8 93.4 23.8 28.1 64.5 146.4 59.5 17.2 33.7 33.1 148.3 234.7 11.8 45.3 169.5 126.3 27.6 271.6 27.3 15.1 30.9 32.1 142.8 8.8 23.9 27.8 104.4 42.1 341.5 91.2 28.0 132.6 18.0 19.6 19.2 19.2 18.0 19.7 23.6 20.5 22.5 21.6 21.1 21.6 3.5 9.6 14.0 8.5 8.6 11.3 26.9 14.0 19.4 1.1 15.3 12.3 226.6 15.7 10.4 11.0 0.0 6.0 38.1 16.2 64.6 45.6 34.5 3.4 2.7 7.1 6.0 19.1 0.3 30.4 7.4 14.9 11.7 5.4 36.2 8.3 5.3 14.2 102.1 0.0 0.7 15.4 10.2 68.0 23.9 86.2 7.2 59.4 7.2 0.0 76.6 17.1 41.2 0.5 2.0 76.2 15.6 3.4 12.7 30.9 30.7 35.4 5.7 2.3 26.3 9.7 12.0 4.1 4.6 34.2 20.2 5.1 24.3 22.0 28.2 33.5 MAPKAPK5 "MK5, PRAK" ENSG00000089022 "MAPK activated protein kinase 5" Q8IW41 12 111842228-111902222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 18.1 20.8 12.6 17.9 14.4 27.1 20.4 14.9 15.0 15.2 15.7 28.2 25.5 15.7 20.7 17.2 16.1 12.2 16.7 15.3 14.3 20.3 19.4 17.5 20.7 12.3 12.4 18.1 20.4 21.4 11.6 20.3 11.8 17.0 30.7 27.2 17.4 15.6 30.4 20.1 28.2 18.9 11.3 15.6 18.0 15.9 12.9 23.2 19.3 25.3 19.3 18.5 14.4 13.8 32.4 42.1 40.0 33.7 28.2 28.4 60.6 31.7 38.1 47.7 32.7 54.8 25.9 48.6 22.9 37.7 28.4 31.6 53.1 33.2 44.4 32.6 29.0 43.4 29.5 44.2 34.1 55.1 29.4 30.2 46.7 45.6 53.7 36.0 35.6 43.4 61.0 18.7 35.3 36.4 55.2 86.6 56.9 79.1 29.4 53.7 29.1 46.9 37.9 46.2 49.0 41.4 36.1 60.5 46.3 36.2 49.1 62.0 31.2 26.8 27.2 27.9 40.4 37.8 50.1 57.4 32.7 39.4 38.9 1.1 3.3 2.3 4.2 2.4 2.2 3.5 2.7 3.0 2.2 3.1 4.2 3.1 1.6 2.9 8.8 2.6 4.8 1.8 12.6 14.4 14.9 15.0 15.3 14.3 12.3 12.4 11.8 11.3 12.9 13.8 16.9 3.2 23.1 12.1 22.3 20.5 22.3 12.5 21.1 47.0 18.3 14.0 20.1 22.8 15.4 3.7 41.7 29.9 32.4 34.1 13.7 28.2 17.2 14.2 17.3 16.0 36.6 15.8 24.6 29.6 33.3 19.4 20.9 15.2 2.5 22.3 14.6 13.4 19.9 23.5 22.3 47.3 14.2 21.2 17.7 7.3 15.5 15.0 8.8 14.0 27.8 19.6 25.7 15.6 21.8 36.3 27.4 17.7 21.6 37.5 63.6 21.8 12.0 36.4 19.7 22.6 19.8 30.7 40.3 23.6 21.3 30.1 22.2 22.5 32.3 32.3 MCRS1 "ICP22BP, INO80Q, MCRS2, MSP58, P78" ENSG00000187778 "Microspherule protein 1" Q96EZ8 12 49556544-49568145 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039057 Supported Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA039057: AB_10794085" "unprognostic (2.60e-3)" "unprognostic (5.23e-2)" "unprognostic (1.46e-1)" "unprognostic (1.89e-2)" "unprognostic (1.68e-1)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (2.26e-2)" "unprognostic (2.83e-3)" "unprognostic (6.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.23e-1)" "prognostic favorable (2.70e-4)" "unprognostic (2.28e-1)" "unprognostic (1.69e-1)" "unprognostic (4.35e-2)" "unprognostic (3.26e-2)" 22.3 29.7 29.2 27.3 29.9 32.1 23.4 28.3 33.4 26.4 27.8 30.3 27.3 31.3 23.7 34.9 30.1 22.9 68.2 29.6 27.2 34.5 24.6 24.3 33.2 29.9 28.1 23.6 32.7 35.7 24.0 24.5 28.5 31.3 25.9 17.2 27.0 26.9 53.2 26.9 29.2 26.1 28.2 32.8 31.8 35.2 29.4 39.4 35.5 61.4 31.1 29.3 26.2 31.4 43.8 81.5 62.9 54.5 33.2 40.9 69.3 37.5 40.4 95.7 53.2 127.3 69.7 72.6 76.4 66.0 43.7 48.5 97.8 89.0 38.3 57.6 120.3 72.4 53.4 46.9 59.6 85.0 76.0 47.7 68.3 63.8 51.3 56.0 71.0 66.0 90.9 48.0 55.4 77.8 59.1 51.1 87.4 40.7 60.1 69.1 50.7 84.0 59.4 40.3 60.6 63.5 40.8 51.7 36.5 42.8 84.4 101.7 51.6 45.8 58.4 44.7 56.7 47.3 50.9 69.2 60.1 49.8 27.8 96.2 63.7 76.4 63.2 82.7 49.1 44.5 53.6 68.1 79.1 46.1 46.8 51.0 31.8 90.7 64.7 53.5 60.4 76.3 29.2 29.9 28.3 33.4 29.6 27.2 29.9 28.1 28.5 28.2 29.4 31.4 17.0 35.3 13.8 6.2 23.3 10.7 25.1 38.5 10.8 15.6 19.8 19.7 24.2 28.6 22.4 23.9 8.4 52.1 22.1 34.3 52.8 37.7 32.1 16.3 15.3 17.4 27.5 35.1 12.8 36.1 51.8 20.2 39.8 15.7 27.3 24.3 15.0 10.5 40.6 23.5 12.6 27.2 28.5 22.0 12.5 37.8 27.4 20.9 28.4 9.4 38.0 28.1 40.2 7.1 12.3 39.7 37.1 27.1 24.3 26.7 34.1 45.4 22.8 20.5 6.6 14.7 26.9 41.6 64.0 27.4 12.6 59.2 25.6 23.7 33.8 27.0 ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50879080-50954257 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008247: AB_1853704, HPA008880: AB_1853702" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (9.57e-3)" "unprognostic (2.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.29e-8)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-2)" "unprognostic (4.75e-2)" "unprognostic (1.43e-2)" "unprognostic (4.27e-3)" "unprognostic (2.30e-1)" "unprognostic (2.47e-1)" "unprognostic (4.09e-1)" 12.1 15.7 12.7 21.9 13.6 15.6 9.3 14.1 16.8 8.9 55.5 30.6 38.3 9.0 8.9 12.8 8.5 12.7 45.0 14.8 15.4 12.6 15.1 11.6 25.8 15.6 16.2 8.0 20.9 32.2 10.0 13.1 16.2 13.8 32.4 14.6 7.2 19.9 26.2 8.8 32.3 18.1 13.9 27.2 26.5 18.8 15.4 21.4 10.9 22.9 22.6 16.8 3.4 14.3 40.5 39.9 52.0 61.0 23.2 25.6 24.2 33.2 24.7 42.2 35.5 18.4 21.8 143.3 12.8 29.7 38.5 32.6 78.1 33.3 48.2 60.0 11.6 36.5 22.8 21.5 68.1 123.9 42.5 16.0 40.3 53.1 85.8 27.8 55.0 83.5 39.9 34.1 29.1 8.4 90.4 12.3 34.8 29.0 15.9 58.0 25.8 41.1 45.9 8.6 63.9 34.0 31.0 18.7 33.0 31.0 14.4 59.0 34.6 30.0 32.7 15.8 44.7 62.9 27.1 70.6 30.2 86.5 32.5 7.5 16.4 20.7 6.5 19.0 5.1 7.1 4.2 7.9 13.3 7.2 3.6 4.5 18.1 9.8 25.7 4.4 4.4 7.4 12.7 13.6 14.1 16.8 14.8 15.4 15.6 16.2 16.2 13.9 15.4 14.3 20.9 9.6 11.9 40.1 32.8 15.2 20.2 13.6 12.5 17.0 10.9 10.0 103.6 11.5 22.6 14.7 14.6 16.7 37.9 39.0 39.2 31.9 18.0 18.5 22.6 18.7 12.0 16.6 35.6 38.6 16.3 19.1 43.3 19.1 16.4 176.4 24.3 9.1 89.7 8.4 45.9 27.3 18.3 93.8 15.1 6.7 11.5 54.5 12.4 47.8 48.3 18.0 48.4 52.3 32.5 35.6 22.3 16.6 61.5 25.0 72.4 17.1 10.6 55.0 6.6 23.0 23.2 59.8 30.6 13.2 10.7 8.6 28.1 22.4 36.5 17.4 METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.2;Oligodendrocyte precursor cells: 132.7;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039885 Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "Actin filaments" "HPA039885: AB_2676725" "unprognostic (2.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-2)" "unprognostic (2.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-1)" "prognostic favorable (7.95e-5)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (6.58e-2)" "unprognostic (6.84e-3)" 4.3 8.1 4.8 4.1 4.5 2.3 6.2 5.5 5.4 6.1 6.1 7.0 5.1 5.0 5.7 4.6 5.7 4.5 7.7 4.9 5.4 7.7 9.3 4.3 5.3 4.9 4.8 5.9 4.4 7.0 4.2 5.1 5.2 6.3 6.9 7.0 4.5 5.6 8.7 5.1 5.1 4.5 4.5 4.3 5.4 3.3 5.2 5.2 7.6 11.2 5.3 4.4 3.3 6.2 8.8 9.2 9.3 7.1 11.3 18.0 6.5 10.6 8.1 10.6 10.9 6.3 5.9 20.2 6.2 8.8 6.7 7.3 12.3 10.9 20.2 12.5 10.8 6.4 6.5 7.3 12.6 12.1 5.6 10.2 16.0 5.9 15.1 11.5 10.3 6.7 13.7 8.9 12.6 6.0 8.4 7.4 7.2 9.2 6.8 4.5 20.2 7.4 15.8 5.0 8.2 6.7 8.8 7.8 12.7 8.9 15.4 7.4 7.8 9.6 7.4 12.3 9.4 6.0 7.6 11.7 13.5 12.0 10.6 2.1 1.4 3.7 2.2 1.0 2.7 3.6 2.6 2.9 1.7 1.8 2.8 3.6 0.6 4.4 1.2 1.8 3.1 1.5 4.8 4.5 5.5 5.4 4.9 5.4 4.9 4.8 5.2 4.5 5.2 6.2 16.5 12.8 24.3 130.2 21.3 44.0 38.1 37.1 23.9 13.6 21.6 15.0 14.3 14.3 20.3 11.0 18.8 11.3 28.7 18.2 11.7 10.6 34.5 19.6 24.7 15.7 9.6 17.0 96.8 11.8 14.1 23.5 16.3 28.2 5.1 18.1 12.8 15.0 10.4 13.5 93.9 17.6 10.2 14.2 50.7 12.6 10.8 17.9 14.2 105.9 6.1 8.7 19.6 132.7 146.1 9.9 13.3 8.2 21.0 57.2 13.0 14.9 18.9 16.1 6.6 60.7 23.2 17.9 10.0 17.4 35.7 8.5 35.5 21.3 16.2 53.1 MFAP3 ENSG00000037749 "Microfibril associated protein 3" P55082 5 154038959-154220478 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.3;Inhibitory neurons: 24.5;Microglial cells: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015883, HPA049198" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA015883: AB_1853840, HPA049198: AB_2680672" "unprognostic (6.02e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (1.58e-3)" "unprognostic (2.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (6.58e-3)" "unprognostic (1.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.53e-2)" "unprognostic (7.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (9.35e-3)" 16.0 8.5 5.4 13.2 5.4 12.1 12.5 8.1 7.0 13.2 10.1 10.8 9.5 12.0 9.8 14.7 9.7 11.8 14.1 5.3 6.3 13.5 13.7 11.3 10.6 5.8 6.2 9.4 7.1 24.4 3.1 19.6 6.3 9.4 10.8 12.2 7.2 9.0 10.4 7.6 9.6 16.6 6.5 11.4 9.6 5.7 5.7 11.8 13.4 17.1 13.0 16.1 6.5 6.0 14.9 19.7 36.5 37.7 29.8 24.7 31.5 26.4 28.0 27.0 37.1 27.4 34.1 25.0 30.6 26.3 25.8 33.5 32.5 35.6 41.9 9.5 21.0 15.7 26.5 12.9 29.5 27.7 16.0 29.2 32.4 35.0 29.1 22.6 38.4 19.9 17.5 20.5 21.4 11.0 15.2 9.9 20.0 16.0 9.9 14.6 40.7 20.8 20.8 21.0 32.1 40.3 27.4 35.0 31.1 30.1 34.6 14.8 32.9 34.3 26.4 19.4 26.9 25.7 33.5 21.4 18.7 19.2 27.4 6.7 7.5 11.9 5.0 7.9 6.9 2.4 4.0 3.5 8.1 2.5 5.2 4.1 6.8 6.5 5.6 3.7 3.9 4.3 5.4 5.4 8.1 7.0 5.3 6.3 5.8 6.2 6.3 6.5 5.7 6.0 9.7 0.0 0.5 14.0 3.5 6.0 1.0 6.1 6.2 3.2 1.6 1.5 2.7 0.0 3.9 5.5 6.2 4.3 2.7 1.9 1.9 1.4 7.1 1.4 4.3 7.6 0.0 9.1 24.3 1.1 3.0 3.9 4.1 2.2 4.5 2.1 1.4 1.9 1.9 3.3 24.5 1.2 8.2 0.6 4.4 4.9 1.8 2.7 8.8 17.8 0.7 6.9 1.0 12.1 15.1 1.1 0.3 0.0 9.5 1.3 2.1 1.1 4.6 4.6 0.0 1.5 3.3 3.9 2.0 4.3 5.5 6.0 4.0 1.2 1.0 1.5 MFN1 FLJ20693 ENSG00000171109 "Mitofusin 1" Q8IWA4 3 179347709-179394936 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033437, HPA059230" Approved Supported Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Mitochondria "CAB033437: AB_2250540, HPA059230: AB_2683952" "unprognostic (2.94e-2)" "unprognostic (5.56e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (6.70e-4)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (6.37e-2)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "unprognostic (3.76e-3)" "unprognostic (7.91e-2)" "unprognostic (7.90e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-1)" "unprognostic (6.24e-2)" "unprognostic (9.79e-2)" 9.5 9.0 5.6 9.4 6.6 8.4 11.0 8.8 8.5 9.5 8.8 12.5 8.9 11.4 14.9 14.1 10.2 9.6 23.4 5.6 5.5 10.4 8.8 8.8 12.8 6.3 5.8 9.1 17.9 13.3 6.7 7.9 6.0 12.4 10.5 10.3 14.1 9.6 14.0 14.5 9.8 11.4 5.2 9.9 10.8 9.0 5.7 8.6 10.4 16.4 11.9 12.7 8.9 9.5 32.2 9.4 17.9 29.1 25.1 23.2 23.6 19.6 20.2 20.2 23.9 23.5 13.0 10.8 20.0 29.1 40.9 18.5 25.4 19.4 35.3 17.2 19.5 17.8 19.4 13.1 20.5 9.5 16.3 16.2 16.7 21.9 15.4 16.8 26.0 17.9 13.2 14.1 28.6 17.1 14.0 7.1 21.3 32.1 17.3 9.7 28.1 40.4 19.1 33.4 16.8 23.9 18.3 48.5 26.6 18.2 66.6 6.8 22.0 17.6 19.4 27.6 29.0 18.6 21.9 18.0 19.7 15.8 19.5 4.2 2.5 5.8 2.6 3.1 4.5 5.1 3.0 2.7 2.3 6.2 2.7 3.2 5.8 2.9 2.4 2.8 2.9 1.4 5.6 6.6 8.8 8.5 5.6 5.5 6.3 5.8 6.0 5.2 5.7 9.5 21.3 25.6 36.8 39.8 27.3 16.7 12.3 12.6 20.5 18.8 19.1 14.4 29.3 14.3 23.7 18.4 39.6 11.2 20.9 18.2 9.8 12.6 6.6 36.9 28.5 16.3 10.2 24.0 77.2 17.4 11.0 22.6 26.0 43.4 8.8 22.1 14.6 18.3 7.8 11.8 92.5 18.2 12.2 11.7 11.4 3.3 13.4 14.9 12.4 28.1 12.2 11.2 18.6 56.8 85.1 16.5 11.8 17.7 21.2 20.0 10.4 13.4 31.9 16.5 6.6 26.8 21.2 33.2 13.7 24.9 27.0 13.1 15.1 25.3 16.6 20.7 MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 270.4;skeletal muscle: 310.5;tongue: 337.6" "Cell type enriched" "Detected in all" 7 "Cardiomyocytes: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB079902: AB_2724683, HPA030554: AB_10603018" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-2)" "unprognostic (8.36e-2)" "unprognostic (9.71e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (3.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.43e-1)" "unprognostic (3.55e-1)" "prognostic favorable (2.36e-8)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" "unprognostic (8.84e-3)" "unprognostic (2.12e-1)" 34.7 31.4 39.9 20.9 42.4 26.7 31.8 39.1 41.4 29.3 17.4 59.7 41.9 37.0 12.7 57.3 26.2 21.8 270.4 34.7 43.0 36.5 58.5 31.1 19.8 41.1 44.8 27.0 22.5 76.7 28.7 27.6 40.6 36.3 38.1 35.0 32.2 62.3 310.5 58.9 46.3 41.2 43.5 31.5 44.9 25.4 48.8 26.1 56.1 337.6 30.4 51.2 36.2 40.5 93.6 54.0 52.6 72.7 59.7 47.2 58.8 76.0 66.1 96.5 72.6 88.7 51.8 68.8 74.8 92.6 60.6 80.5 101.7 156.1 90.6 60.6 75.4 94.5 81.8 54.2 53.8 114.2 51.9 57.0 105.1 133.1 124.5 40.1 66.2 26.4 106.1 53.6 69.7 30.2 60.2 15.2 39.7 57.8 77.4 68.2 95.8 58.5 44.9 61.4 68.2 44.6 88.4 81.0 74.6 41.4 43.8 49.2 71.2 63.1 58.3 88.4 71.2 59.0 86.4 120.7 69.0 99.6 69.8 10.4 11.5 7.6 8.9 14.0 10.2 6.7 6.7 7.9 9.7 4.8 5.0 6.2 16.2 6.2 18.3 4.2 8.1 15.7 39.9 42.4 39.1 41.4 34.7 43.0 41.1 44.8 40.6 43.5 48.8 40.5 18.1 22.4 15.8 16.6 10.2 22.8 9.4 18.9 19.9 26.7 17.4 16.4 336.9 7.2 14.9 14.7 12.5 15.1 12.5 39.2 21.5 13.6 4.7 8.9 12.1 18.5 18.0 32.4 21.5 20.4 15.5 17.3 17.3 12.8 10.8 12.8 11.7 46.3 16.0 30.3 24.5 22.2 18.3 23.9 9.7 8.0 7.2 19.1 17.8 8.4 17.3 14.6 8.2 11.1 16.7 18.5 16.8 15.1 10.9 13.9 41.8 14.3 12.9 21.0 13.1 16.0 16.5 25.9 15.6 25.1 30.1 25.2 10.3 12.5 26.4 16.6 MICU1 "CALC, CBARA1, EFHA3, FLJ12684" ENSG00000107745 "Mitochondrial calcium uptake 1" Q9BPX6 10 72367327-72626191 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 185.5;Inhibitory neurons: 205.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037479, HPA037480" Approved Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA037479: AB_2675495, HPA037480: AB_10696934" "unprognostic (8.18e-2)" "unprognostic (6.98e-3)" "unprognostic (6.71e-2)" "unprognostic (8.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (3.60e-2)" "unprognostic (2.96e-3)" "unprognostic (3.38e-2)" "unprognostic (7.43e-2)" "unprognostic (2.23e-2)" "prognostic favorable (4.66e-7)" "unprognostic (1.70e-1)" "unprognostic (1.55e-1)" "unprognostic (5.35e-2)" "unprognostic (6.70e-2)" 30.9 55.3 34.4 21.2 37.2 34.2 26.4 51.4 47.1 28.8 27.8 30.1 37.4 36.5 23.8 20.7 34.6 32.3 43.9 37.8 32.2 105.3 116.7 29.6 20.1 32.2 30.7 41.6 20.0 43.3 24.4 23.6 33.7 24.8 32.9 31.5 20.8 22.3 72.2 29.0 32.7 38.4 29.0 27.0 43.3 20.2 30.4 26.1 22.9 76.9 21.6 30.8 21.7 34.1 42.2 71.8 45.4 53.3 70.8 66.6 20.6 45.8 101.6 65.7 89.8 42.2 77.2 56.8 37.3 63.5 54.0 49.1 57.7 40.7 76.9 51.9 46.6 38.3 37.1 61.2 56.4 53.3 40.1 66.6 36.2 72.4 66.5 90.4 57.7 53.4 60.0 64.5 77.6 37.9 46.7 49.9 19.0 45.0 17.3 50.5 60.9 37.4 80.8 31.0 34.8 49.8 54.2 65.9 42.0 45.2 39.3 50.5 36.2 32.6 50.1 65.7 38.4 33.9 62.6 39.2 65.1 69.6 22.5 21.5 60.0 110.8 16.8 49.8 14.7 15.1 14.7 15.5 26.0 17.5 14.4 12.0 48.8 15.2 54.5 16.5 15.3 35.4 34.4 37.2 51.4 47.1 37.8 32.2 32.2 30.7 33.7 29.0 30.4 34.1 30.4 54.5 36.0 47.7 23.4 9.9 16.0 22.6 14.2 31.9 25.3 19.6 35.8 25.8 38.3 35.0 20.9 20.7 16.9 25.9 80.3 35.6 10.7 42.0 43.0 22.7 14.4 25.0 185.5 26.7 18.8 31.1 45.9 48.2 18.3 31.5 23.9 60.4 34.8 16.8 205.9 24.4 16.2 36.9 13.4 12.5 26.8 40.1 12.4 64.6 38.0 51.3 10.3 146.8 97.5 51.4 24.9 25.9 25.0 10.7 29.3 110.7 34.0 33.8 6.6 29.0 27.2 54.5 40.0 14.2 14.2 21.5 19.0 73.4 23.6 14.2 MICU2 EFHA1 ENSG00000165487 "Mitochondrial calcium uptake 2" Q8IYU8 13 21492691-21604181 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045511, HPA058790" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA045511: AB_10959894, HPA058790: AB_2683821" "unprognostic (4.32e-3)" "unprognostic (1.50e-2)" "unprognostic (2.00e-1)" "unprognostic (7.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.11e-2)" "unprognostic (1.47e-2)" "unprognostic (8.01e-2)" "unprognostic (4.79e-3)" "unprognostic (1.63e-3)" "unprognostic (1.58e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.81e-2)" "unprognostic (8.94e-2)" "unprognostic (5.15e-2)" "unprognostic (3.50e-1)" 22.6 44.4 19.3 24.5 21.0 36.3 32.4 23.9 29.7 26.2 24.2 37.6 26.5 22.1 27.8 23.2 25.1 20.2 57.5 20.4 20.4 76.3 32.2 23.0 26.9 21.8 20.6 22.7 21.3 45.9 27.0 24.5 20.2 28.5 34.1 45.7 23.4 22.1 56.4 22.9 27.4 21.1 20.8 22.6 30.6 27.0 19.7 28.8 37.6 61.5 29.7 23.5 18.7 24.2 35.2 20.0 46.2 29.6 40.4 53.8 39.7 58.3 47.5 60.8 42.0 29.0 55.6 54.4 36.8 56.0 31.3 45.9 45.9 49.1 83.4 55.5 46.5 94.2 20.5 34.3 48.7 71.4 52.7 46.8 47.7 34.5 24.4 54.4 41.2 50.5 33.9 23.9 100.3 30.8 47.9 68.1 31.5 123.2 30.3 51.9 117.2 36.6 121.3 28.6 36.9 28.6 39.8 46.4 39.6 40.2 45.3 66.7 51.1 26.4 23.6 54.1 48.9 17.7 24.8 39.6 26.1 59.0 66.8 34.0 24.8 35.1 30.6 30.5 28.0 42.1 26.9 30.9 27.3 24.4 23.7 30.2 23.3 30.2 25.6 25.1 40.3 23.9 19.3 21.0 23.9 29.7 20.4 20.4 21.8 20.6 20.2 20.8 19.7 24.2 22.0 38.5 26.8 70.2 51.3 30.0 39.8 51.9 26.2 27.1 24.0 17.8 74.5 30.0 46.8 51.5 22.9 60.7 31.8 52.2 144.8 43.3 40.7 39.7 28.4 24.3 30.5 65.2 126.1 27.2 42.6 32.0 27.0 28.7 24.7 26.5 17.9 24.0 36.5 42.1 142.5 25.7 57.0 28.8 22.1 16.2 33.8 28.5 48.0 55.3 43.1 63.9 43.3 77.9 121.7 36.9 51.7 36.1 29.3 27.8 31.3 108.4 56.0 49.0 59.2 37.6 30.7 86.9 48.5 23.0 25.6 70.3 45.5 47.4 34.2 30.0 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993350-37050846 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 15.6 17.9 7.3 17.4 8.0 22.1 15.4 7.1 9.1 17.4 7.6 17.4 12.0 16.3 14.0 14.3 14.9 11.1 35.4 6.9 8.3 16.0 19.1 15.8 21.9 8.6 7.4 15.1 16.6 22.4 22.7 14.8 7.6 16.2 14.5 9.6 12.1 14.0 49.1 13.4 13.4 19.2 7.1 18.8 15.5 25.4 7.7 28.4 19.2 42.2 24.3 17.2 14.0 9.0 37.1 56.7 66.7 0.2 25.9 34.5 30.7 54.7 44.4 64.1 62.3 43.4 40.1 92.2 25.0 44.1 33.6 24.7 65.2 45.8 68.5 42.2 32.1 68.1 42.3 54.9 23.2 81.9 40.5 28.4 29.0 54.8 57.8 21.9 37.6 55.0 86.0 32.0 66.2 27.6 81.0 22.2 49.4 38.4 31.6 4.6 90.6 40.2 35.1 39.3 14.2 36.1 52.1 56.9 32.7 33.3 79.9 55.6 28.8 46.0 50.5 44.0 65.9 29.1 93.7 88.1 37.8 71.9 45.7 12.6 12.5 15.1 12.7 22.6 9.8 11.3 7.7 11.4 14.3 9.7 8.4 9.6 2.6 7.8 29.2 5.9 15.0 11.0 7.3 8.0 7.1 9.1 6.9 8.3 8.6 7.4 7.6 7.1 7.7 9.0 10.8 25.6 15.8 22.9 18.5 7.1 12.4 18.7 7.4 18.5 9.6 9.7 41.8 12.8 15.8 11.0 10.4 33.4 16.0 6.1 19.6 14.6 31.3 12.5 11.3 10.7 5.4 19.0 18.5 14.7 26.9 14.4 12.2 9.5 7.6 13.0 13.6 14.9 20.1 3.3 21.6 8.6 16.2 16.3 8.9 13.2 11.1 13.8 8.8 10.3 18.2 15.9 11.3 27.2 31.3 9.3 7.4 13.9 22.1 6.4 5.3 12.9 16.5 18.1 13.1 10.0 14.0 58.6 29.3 9.3 5.5 20.0 15.9 14.8 8.4 6.5 MLIP "C6orf142, CIP, MGC18257" ENSG00000146147 "Muscular LMNA interacting protein" Q5VWP3 6 53929982-54266280 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 209.2;liver: 131.3;skeletal muscle: 246.6;tongue: 149.5" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 224.9;Excitatory neurons: 244.1" "Group enriched" "Detected in some" 4 "glioma: 0.8;head and neck cancer: 0.5;liver cancer: 1.9;melanoma: 1.4" "Group enriched" "Detected in some" 5 "cerebral cortex: 15.4;hippocampal formation: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HUVEC TERT2: 19.6;SK-MEL-30: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029252, HPA046654" Approved Approved Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA029252: AB_2732446, HPA046654: " "unprognostic (7.95e-3)" "unprognostic (4.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.06e-4)" "unprognostic (2.38e-2)" "unprognostic (1.26e-2)" "unprognostic (5.60e-2)" "unprognostic (2.74e-2)" "unprognostic (1.89e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.91e-5)" "unprognostic (7.49e-2)" "unprognostic (2.65e-2)" "unprognostic (5.27e-2)" "unprognostic (3.29e-3)" 3.7 4.3 0.1 0.1 2.2 0.0 3.5 0.0 15.4 1.7 0.0 0.9 0.3 0.2 0.9 12.6 0.7 1.6 209.2 6.0 0.0 0.9 131.3 0.4 0.2 0.0 0.0 0.2 0.8 0.3 0.5 0.1 0.0 1.6 0.7 0.9 6.9 0.3 246.6 17.4 2.6 0.5 0.0 0.1 0.3 1.0 0.0 0.3 6.9 149.5 5.2 1.3 2.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.0 0.0 19.6 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.2 0.0 0.1 0.6 1.4 0.0 0.0 0.5 19.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 15.4 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.4 0.1 0.5 0.6 0.1 0.2 0.0 224.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 15.7 0.5 0.5 2.6 0.0 2.7 244.1 0.0 0.0 4.9 0.0 0.4 0.0 0.1 0.7 20.0 0.0 13.5 4.6 3.7 0.0 0.8 0.6 12.9 0.3 0.2 7.2 16.9 0.0 0.0 0.0 5.0 4.2 0.0 0.0 0.0 0.0 0.1 1.0 1.9 0.6 0.1 0.0 17.8 1.9 1.5 0.4 4.1 2.0 0.0 0.1 0.1 0.1 0.1 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MRPL1 BM022 ENSG00000169288 "Mitochondrial ribosomal protein L1" Q9BYD6 4 77862830-77952785 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043656 Supported Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043656: AB_2678601" "unprognostic (9.03e-3)" "unprognostic (3.25e-1)" "unprognostic (1.11e-3)" "unprognostic (2.88e-1)" "unprognostic (4.52e-2)" "unprognostic (5.29e-3)" "unprognostic (4.69e-3)" "unprognostic (5.44e-2)" "unprognostic (1.66e-2)" "unprognostic (5.14e-3)" "unprognostic (8.79e-2)" "unprognostic (2.22e-2)" "prognostic favorable (3.35e-5)" "unprognostic (7.63e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "unprognostic (9.17e-3)" 19.4 17.7 17.1 17.4 17.7 26.9 24.4 16.8 20.9 16.5 15.7 28.3 19.5 18.6 21.0 20.5 17.0 11.8 41.7 17.9 18.2 38.1 33.8 13.1 23.6 17.3 17.1 19.0 14.1 21.4 8.1 21.4 17.9 16.0 29.4 14.5 19.3 15.0 67.3 14.6 18.6 21.4 17.1 15.0 17.8 8.8 17.8 19.3 17.7 67.6 24.2 19.8 9.2 17.7 40.5 26.2 47.3 40.7 36.6 47.4 41.2 44.6 28.6 57.4 39.3 55.0 71.6 71.4 53.9 37.1 35.8 32.8 71.1 82.5 75.6 47.6 37.6 61.1 27.6 60.4 47.5 126.2 28.3 37.7 76.7 51.2 53.0 37.8 70.4 50.1 90.3 24.1 73.6 46.0 76.0 84.9 52.0 92.0 34.3 90.7 60.6 41.1 113.3 43.2 52.1 25.9 36.1 88.7 84.5 38.0 43.7 61.0 41.9 37.5 54.3 37.7 65.1 21.1 28.1 74.6 31.9 71.8 49.3 9.0 11.5 7.0 20.6 19.0 20.6 27.8 22.2 23.1 22.1 25.5 26.8 29.5 1.7 23.2 16.9 18.0 25.8 15.4 17.1 17.7 16.8 20.9 17.9 18.2 17.3 17.1 17.9 17.1 17.8 17.7 40.1 25.6 35.7 22.5 45.7 12.7 17.1 68.6 13.6 24.6 31.6 37.2 122.1 57.2 33.5 33.1 18.8 72.7 75.5 22.2 135.0 46.0 15.5 33.9 40.9 34.9 47.9 34.9 45.9 36.7 51.9 27.5 18.8 38.5 42.4 38.7 40.7 134.3 47.7 25.2 39.7 60.5 61.1 25.1 12.7 9.3 31.1 23.5 16.0 35.6 34.1 26.7 64.9 45.2 47.7 28.3 24.9 33.4 38.6 14.7 36.0 144.8 20.6 42.4 39.5 31.4 45.9 21.1 48.0 23.1 12.8 34.9 65.8 61.7 70.9 15.5 MRPL13 "L13, L13A, L13mt, RPL13, RPML13" ENSG00000172172 "Mitochondrial ribosomal protein L13" Q9BYD1 8 120380761-120445402 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 264.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 497.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060899 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA060899: AB_2684382" "prognostic unfavorable (1.37e-4)" "unprognostic (4.91e-2)" "unprognostic (8.50e-2)" "unprognostic (3.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-1)" "unprognostic (7.28e-3)" "unprognostic (1.34e-3)" "unprognostic (1.18e-1)" "unprognostic (1.56e-2)" "unprognostic (1.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.84e-1)" 21.3 37.8 18.2 19.1 18.5 22.1 26.6 19.5 27.3 17.0 20.0 37.6 24.4 16.3 24.2 35.6 16.2 15.8 38.2 17.7 20.3 45.6 51.1 16.4 24.8 18.9 19.0 13.1 18.1 33.5 15.2 20.9 19.1 18.2 36.5 21.4 22.0 14.6 33.8 17.7 22.5 19.3 20.1 18.3 24.2 15.1 19.2 28.2 18.2 47.2 25.0 24.7 21.8 20.4 106.5 53.8 62.8 52.7 43.0 62.7 51.2 58.3 57.1 81.3 88.5 56.6 80.2 78.8 85.4 49.4 54.6 56.5 82.1 74.9 114.2 107.4 84.2 99.6 39.0 81.8 51.8 62.7 47.1 48.7 123.2 68.6 71.8 46.4 67.2 78.7 103.8 56.5 73.4 59.7 101.8 60.9 60.5 194.0 122.7 52.9 61.1 107.7 90.7 57.1 74.0 38.1 41.0 497.7 78.4 55.1 96.0 65.9 39.3 42.0 87.1 53.3 107.7 45.2 98.9 110.7 77.8 112.6 76.3 48.4 59.7 66.0 47.6 92.2 56.1 58.9 57.4 62.4 89.8 46.8 55.1 56.4 10.4 68.3 103.1 72.4 77.2 92.2 18.2 18.5 19.5 27.3 17.7 20.3 18.9 19.0 19.1 20.1 19.2 20.4 48.4 70.5 41.9 5.5 37.2 33.6 55.9 235.1 46.7 18.3 37.8 52.1 119.6 44.3 117.8 55.2 20.9 134.2 33.2 56.4 262.2 121.0 10.4 68.4 53.1 45.6 45.0 54.5 14.7 100.7 171.0 49.1 30.5 51.4 36.8 39.3 35.0 78.1 103.3 16.8 14.1 93.3 177.0 33.6 31.4 9.4 38.2 47.5 32.0 9.4 80.1 49.9 32.0 10.1 14.3 95.1 84.9 35.3 42.3 46.5 81.9 264.8 140.7 25.6 39.5 29.0 66.4 103.2 64.8 65.3 45.3 115.9 39.9 114.0 100.8 70.2 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 MRPL3 "MRL3, RPML3" ENSG00000114686 "Mitochondrial ribosomal protein L3" P09001 3 131462212-131502983 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043665, HPA060132" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043665: AB_2678606, HPA060132: AB_2684209" "unprognostic (1.75e-2)" "unprognostic (7.23e-2)" "unprognostic (2.61e-2)" "unprognostic (1.61e-3)" "unprognostic (7.83e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.33e-7)" "unprognostic (1.54e-1)" "unprognostic (8.23e-2)" "prognostic favorable (1.36e-4)" "prognostic unfavorable (3.51e-6)" "unprognostic (2.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (3.29e-1)" 46.2 44.3 22.9 45.1 24.2 32.0 65.4 23.0 28.7 47.0 29.4 60.8 48.7 40.8 71.6 51.0 59.3 34.9 48.6 24.2 28.0 75.2 65.6 29.9 51.4 22.9 23.8 47.9 61.1 80.9 38.2 39.6 24.9 45.7 65.9 33.8 57.5 48.1 78.6 34.5 41.3 50.4 25.6 29.8 46.7 51.1 25.6 53.1 64.2 78.0 60.9 65.8 35.0 26.9 263.1 108.9 119.8 135.0 110.5 142.4 216.4 139.7 122.6 177.0 156.7 241.4 148.5 212.3 184.3 140.8 138.9 168.5 205.9 200.8 269.6 138.4 160.1 197.2 112.3 204.8 129.2 399.8 121.7 112.7 163.6 136.4 241.0 96.1 116.4 159.7 183.3 113.0 148.2 200.1 201.3 199.6 255.2 278.6 193.7 79.4 153.8 326.3 176.3 182.1 194.1 130.5 125.4 141.4 206.3 100.0 165.5 211.6 105.8 127.2 132.5 181.6 196.8 107.0 116.0 380.4 135.6 189.6 178.6 12.8 79.0 19.7 58.7 105.9 91.2 71.9 71.9 70.2 147.5 76.3 82.7 75.1 4.5 98.3 80.5 51.5 77.1 124.6 22.9 24.2 23.0 28.7 24.2 28.0 22.9 23.8 24.9 25.6 25.6 26.9 32.5 25.6 26.9 22.5 54.4 45.9 89.0 106.8 49.5 28.3 54.2 52.8 35.7 37.1 63.8 31.3 8.4 100.2 37.6 26.6 152.6 115.7 86.4 39.0 58.6 31.6 30.1 57.2 38.3 101.9 135.4 53.3 42.8 65.2 28.6 55.1 31.1 50.7 65.9 30.3 30.3 76.2 67.1 54.1 37.3 24.2 55.6 51.5 42.7 19.7 55.5 35.6 49.4 33.7 30.3 92.4 31.9 51.6 72.9 97.8 47.4 167.2 38.9 21.9 32.9 59.8 54.2 149.3 85.4 67.6 47.5 63.9 42.5 95.0 81.3 84.0 MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043482: AB_10959449" "unprognostic (3.68e-2)" "unprognostic (6.24e-2)" "unprognostic (9.14e-3)" "unprognostic (1.68e-2)" "unprognostic (9.38e-3)" "unprognostic (7.72e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.81e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "prognostic favorable (9.96e-6)" "unprognostic (1.94e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-3)" 25.0 29.7 19.6 24.7 22.0 20.5 25.3 21.2 26.1 18.9 18.8 55.5 57.9 17.8 13.6 31.2 21.9 19.9 83.8 20.1 21.9 47.5 46.1 15.5 35.6 19.7 19.6 17.3 19.7 45.9 12.0 20.9 20.9 19.1 58.7 23.2 24.3 25.1 69.4 14.3 43.3 30.1 20.5 21.6 32.2 16.2 21.7 29.1 19.9 113.5 40.0 32.2 18.0 21.2 83.4 35.8 53.6 55.0 55.1 51.6 77.2 71.5 51.5 88.0 64.9 31.4 69.1 154.1 79.0 61.6 70.9 71.2 109.3 64.2 98.1 89.0 51.0 88.5 25.9 80.5 44.7 143.0 68.0 38.6 75.0 95.4 46.4 42.3 81.4 82.6 111.4 66.1 82.0 50.2 82.0 97.3 56.2 107.0 46.4 71.4 143.1 129.8 90.6 60.2 45.2 43.7 66.1 106.8 116.8 37.5 43.7 57.0 62.2 70.4 85.9 89.8 112.6 49.9 157.4 170.0 61.7 150.1 65.6 30.4 36.0 19.0 21.4 48.4 24.0 45.2 31.9 28.0 41.9 41.4 37.4 29.7 5.1 23.5 50.8 42.2 40.4 32.4 19.6 22.0 21.2 26.1 20.1 21.9 19.7 19.6 20.9 20.5 21.7 21.2 17.3 22.4 15.0 7.2 17.5 7.1 20.3 67.4 11.4 21.9 17.0 20.1 135.9 18.6 42.2 18.4 31.3 49.2 15.0 46.7 97.8 42.0 3.7 22.0 28.3 19.2 26.5 35.1 11.6 43.0 49.7 19.8 23.4 22.1 21.0 21.9 15.7 52.9 65.3 23.5 12.7 31.4 48.8 23.8 6.1 5.0 12.8 23.7 10.6 12.2 32.1 21.5 19.6 5.0 11.5 41.8 29.5 17.7 29.5 17.3 52.6 82.8 24.9 25.4 26.3 17.2 47.2 14.6 26.3 29.0 8.5 27.0 14.6 38.1 56.3 25.2 MRPL39 "C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5" ENSG00000154719 "Mitochondrial ribosomal protein L39" Q9NYK5 21 25585656-25607517 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.5;Spermatocytes: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018331 Approved Supported Mitochondria NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA018331: AB_1854111" "unprognostic (3.81e-3)" "unprognostic (5.34e-2)" "unprognostic (8.55e-3)" "unprognostic (4.61e-1)" "unprognostic (2.61e-1)" "unprognostic (4.32e-2)" "unprognostic (6.75e-2)" "unprognostic (2.35e-1)" "unprognostic (4.74e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (5.84e-4)" "unprognostic (7.48e-2)" "unprognostic (7.32e-3)" "unprognostic (9.81e-2)" "unprognostic (1.66e-1)" "unprognostic (2.45e-2)" "unprognostic (6.89e-2)" 23.1 35.6 18.2 19.7 19.6 22.7 26.7 22.1 28.7 16.7 18.4 29.2 25.5 18.0 41.7 26.5 20.4 13.5 51.4 18.3 19.2 40.4 55.3 15.3 34.2 18.7 18.1 17.6 25.2 71.0 13.4 26.2 19.8 20.0 32.1 21.5 21.8 17.8 58.6 20.3 23.1 22.0 19.0 17.6 22.9 54.7 18.2 24.9 20.1 56.7 37.3 22.3 18.8 21.6 89.6 43.0 60.1 38.1 29.7 42.9 92.3 56.1 50.0 77.0 64.7 85.2 49.2 97.9 30.9 35.4 69.8 25.5 128.5 76.4 85.9 49.1 66.3 100.1 43.0 91.4 34.6 102.4 31.7 34.8 66.7 76.3 62.2 42.7 58.2 99.6 112.3 78.4 77.1 56.0 67.5 55.5 95.6 88.9 65.4 77.8 97.0 103.1 80.6 35.7 37.9 36.3 51.6 94.5 76.3 42.3 68.3 57.6 36.4 40.8 61.0 43.9 69.6 54.9 74.6 121.9 61.2 109.1 62.5 41.9 16.9 20.7 37.0 30.3 46.9 62.0 45.0 42.3 31.0 49.1 43.9 39.3 2.8 36.7 21.6 43.2 56.4 18.6 18.2 19.6 22.1 28.7 18.3 19.2 18.7 18.1 19.8 19.0 18.2 21.6 18.3 25.6 10.5 9.8 17.6 20.0 20.3 71.0 7.4 20.4 14.0 23.5 78.2 10.0 36.2 25.8 10.4 46.8 14.1 8.7 31.3 36.0 241.5 20.9 12.7 22.2 7.8 22.3 11.4 33.8 41.7 19.4 7.1 11.8 15.2 11.3 18.9 19.8 30.8 10.1 11.7 11.4 30.5 10.6 15.7 37.0 14.9 11.3 19.6 9.4 17.1 19.0 11.3 9.5 13.2 26.5 9.3 23.3 13.6 13.2 20.4 46.8 41.8 15.0 46.0 18.1 25.4 103.0 29.4 10.7 16.9 36.9 14.9 25.7 20.1 17.3 MRPS18B "C6orf14, HSPC183, MRPS18-2, PTD017" ENSG00000204568 "Mitochondrial ribosomal protein S18B" Q9Y676 6 30617840-30626395 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043485, HPA050334" Supported Supported "Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Cell Junctions" "HPA043485: AB_2678506, HPA050334: AB_2681091" "unprognostic (8.18e-3)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (2.51e-2)" "unprognostic (4.20e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (2.98e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-2)" "prognostic favorable (3.99e-5)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.39e-2)" 37.2 52.0 43.6 27.6 45.7 20.3 61.0 46.8 44.3 41.1 43.2 52.3 49.8 31.3 57.6 39.3 62.5 27.4 108.1 40.5 44.1 77.9 99.8 39.4 43.6 46.0 45.2 63.0 47.0 74.0 29.2 38.4 46.2 32.0 62.3 41.6 58.0 42.4 180.2 45.1 39.4 38.1 45.2 39.3 44.4 22.0 46.1 43.7 54.1 229.0 63.6 33.0 29.4 48.2 112.7 68.3 51.1 73.5 72.9 101.8 92.6 39.8 92.6 122.8 75.5 117.7 51.8 112.6 91.5 61.7 91.3 86.1 115.0 109.9 122.0 68.7 122.9 107.9 45.1 124.2 67.2 105.7 45.4 88.8 139.4 99.5 273.8 82.7 72.4 104.7 171.3 107.7 112.2 83.1 70.6 111.4 40.6 86.1 81.8 91.2 69.8 220.7 114.8 49.5 111.3 38.4 34.7 147.1 163.0 46.0 190.6 58.4 39.6 79.2 80.8 47.3 70.8 89.5 114.1 99.2 38.3 154.6 121.7 79.2 72.4 42.5 77.0 94.4 104.7 153.5 104.3 86.3 79.8 140.3 129.6 103.5 7.2 120.3 101.4 74.3 108.1 108.4 43.6 45.7 46.8 44.3 40.5 44.1 46.0 45.2 46.2 45.2 46.1 48.2 59.4 60.9 56.1 7.2 58.4 36.8 65.9 114.0 58.6 47.4 56.6 73.0 175.5 117.2 75.0 47.8 64.6 121.2 43.7 39.1 193.7 103.8 54.2 37.5 42.8 59.4 31.3 45.4 6.0 92.1 124.9 47.4 39.3 30.8 37.4 53.1 61.8 121.6 81.4 43.7 7.9 59.5 75.3 53.2 30.4 37.4 70.2 39.7 60.5 1.9 80.0 46.9 70.0 4.5 14.4 69.5 49.9 44.8 56.8 53.2 89.6 201.6 60.4 69.4 52.6 50.0 53.0 29.6 57.4 61.7 44.9 96.5 43.9 144.4 85.3 50.1 MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139357223 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA006083: AB_1854122, HPA007830: AB_1854123" "unprognostic (8.38e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (5.22e-3)" "unprognostic (5.45e-3)" "unprognostic (4.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" "unprognostic (4.49e-3)" "prognostic unfavorable (1.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.22e-3)" "unprognostic (2.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.77e-1)" "unprognostic (3.40e-1)" 25.5 55.6 23.1 20.7 24.2 37.9 25.2 27.2 31.5 21.9 22.2 35.0 37.0 20.2 19.3 37.4 20.5 17.3 61.3 23.4 27.3 38.0 57.4 17.0 22.8 24.9 23.4 22.6 32.0 31.7 13.7 25.6 26.0 17.1 31.9 17.9 22.0 20.2 83.0 21.8 33.1 23.9 25.8 17.0 25.0 35.4 24.4 23.5 22.8 77.3 24.4 27.3 21.6 27.4 101.2 40.4 40.0 44.5 49.1 41.7 79.1 58.9 72.3 97.1 80.7 130.0 68.3 66.5 106.9 67.1 98.9 109.9 64.6 76.5 96.4 39.0 64.1 105.2 35.8 97.2 56.2 99.3 58.1 45.2 59.6 58.3 61.8 49.2 61.0 76.2 149.2 41.7 61.2 72.4 51.9 85.9 64.4 102.3 73.3 65.0 61.3 98.9 75.0 61.4 43.4 40.4 94.2 141.4 154.6 37.0 97.1 93.7 47.5 42.4 42.3 82.4 55.9 66.3 38.5 119.5 56.9 70.6 42.3 42.8 38.4 36.1 34.9 53.4 43.0 40.3 37.5 39.4 45.8 36.1 41.0 38.9 9.2 38.1 53.6 29.7 47.6 36.3 23.1 24.2 27.2 31.5 23.4 27.3 24.9 23.4 26.0 25.8 24.4 27.4 30.7 19.2 13.4 8.8 21.8 22.8 29.7 63.3 19.4 19.9 15.3 18.0 50.3 25.8 33.3 18.4 14.6 62.9 24.9 26.5 68.4 47.5 84.3 19.9 30.5 26.6 15.6 31.2 8.7 60.3 48.0 27.7 16.3 22.0 27.3 24.9 18.2 38.9 48.6 20.2 13.8 26.5 32.6 21.9 16.1 14.3 23.3 22.5 16.0 4.7 38.0 21.8 24.7 10.1 10.1 42.0 27.1 23.7 38.4 16.6 45.4 59.4 35.5 26.2 39.5 32.2 39.1 102.2 51.4 34.8 20.5 75.4 24.7 74.1 46.5 31.2 MRPS23 "CGI-138, HSPC329, MRP-S23" ENSG00000181610 "Mitochondrial ribosomal protein S23" Q9Y3D9 17 57834781-57850056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 187.7;Proximal tubular cells: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023453 Supported Supported "Nuclear membrane,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear membrane" "HPA023453: AB_1854125" "unprognostic (3.84e-3)" "unprognostic (3.36e-1)" "unprognostic (1.75e-2)" "unprognostic (2.00e-2)" "unprognostic (7.96e-2)" "unprognostic (3.06e-3)" "prognostic unfavorable (9.52e-4)" "unprognostic (3.71e-1)" "unprognostic (7.92e-2)" "unprognostic (2.63e-3)" "unprognostic (1.39e-2)" "unprognostic (8.74e-2)" "unprognostic (3.74e-2)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (2.83e-1)" 21.7 37.5 22.7 26.4 23.5 24.4 25.4 22.9 29.6 17.8 21.4 22.2 23.8 25.3 29.7 25.1 24.8 16.7 86.3 23.6 23.3 38.5 24.5 21.9 31.1 23.3 23.7 20.2 39.6 47.5 20.3 20.6 24.8 36.2 20.3 31.9 20.9 24.8 61.5 19.8 20.7 21.8 23.5 21.7 39.4 23.4 23.2 30.3 36.7 44.5 26.9 28.2 18.0 25.2 137.6 137.0 71.7 75.7 42.6 49.5 82.5 86.9 64.9 118.4 90.8 102.6 80.1 173.1 251.9 67.0 109.3 66.3 113.8 102.3 98.2 137.7 135.9 125.4 51.3 179.9 80.9 165.7 115.9 45.4 89.9 87.9 90.8 54.0 75.8 90.9 190.5 60.4 94.0 117.8 154.8 96.1 86.8 153.7 142.8 111.1 120.4 144.0 91.7 65.1 95.8 149.2 65.5 54.5 177.6 52.0 169.1 121.8 66.9 100.0 127.5 100.8 186.3 131.6 301.3 197.5 95.1 102.3 93.7 67.7 41.2 66.2 39.2 51.5 41.2 44.3 38.9 39.9 57.8 47.9 41.3 41.5 6.6 47.2 37.8 54.6 41.3 45.8 22.7 23.5 22.9 29.6 23.6 23.3 23.3 23.7 24.8 23.5 23.2 25.2 34.9 48.1 33.6 3.6 30.2 33.4 40.4 109.4 26.7 41.6 30.1 42.4 187.7 27.1 60.5 47.8 12.5 81.6 30.0 18.4 148.7 84.8 5.9 42.5 37.0 40.0 22.1 28.4 6.1 100.0 87.0 37.4 29.6 36.3 23.4 43.9 24.3 39.7 85.5 50.5 6.8 29.2 69.2 35.2 23.5 10.0 32.6 31.5 40.9 4.7 67.1 63.1 48.4 2.5 10.0 87.7 25.5 39.5 29.1 58.9 20.8 190.8 55.6 64.4 26.3 37.5 43.8 38.3 85.9 39.3 32.5 42.5 27.4 65.4 40.9 34.2 MRPS27 KIAA0264 ENSG00000113048 "Mitochondrial ribosomal protein S27" Q92552 5 72219403-72320646 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071751 Approved Supported Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA071751: AB_2686442" "unprognostic (3.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.14e-3)" "unprognostic (3.60e-2)" "unprognostic (2.23e-2)" "unprognostic (1.63e-1)" "unprognostic (1.79e-2)" "unprognostic (7.20e-3)" "unprognostic (2.12e-1)" "unprognostic (3.22e-3)" "unprognostic (5.07e-2)" "unprognostic (3.26e-2)" "unprognostic (6.58e-3)" "unprognostic (1.33e-1)" "unprognostic (5.27e-2)" "unprognostic (7.73e-2)" "unprognostic (3.95e-2)" 25.5 36.1 23.8 21.8 25.3 18.9 31.8 23.6 27.8 27.0 33.8 26.2 20.4 25.8 27.6 32.4 31.3 19.0 55.5 25.0 23.1 30.5 38.5 17.5 36.9 24.6 24.1 39.5 27.1 32.7 20.9 21.2 24.6 25.2 31.5 17.7 22.4 30.3 58.7 31.7 22.0 26.9 24.5 25.9 25.7 15.1 25.0 30.7 35.6 89.1 41.9 29.7 26.0 24.1 49.7 65.2 56.8 94.4 73.1 93.5 73.0 46.7 66.4 86.9 69.7 81.9 68.5 128.2 63.8 54.8 94.9 54.0 111.8 166.1 93.6 48.6 69.2 66.0 71.3 91.1 72.7 58.4 49.0 88.1 68.7 91.3 101.5 79.0 94.2 92.2 67.2 37.5 73.0 59.7 87.8 70.4 65.7 35.8 40.4 92.0 94.4 131.5 80.7 52.4 87.5 46.7 78.5 63.8 58.5 52.2 97.8 69.9 54.1 35.3 51.8 50.3 85.2 37.7 61.0 89.1 60.9 94.6 57.0 15.5 23.4 8.1 24.9 27.5 37.1 36.1 30.6 30.4 44.2 32.1 35.2 37.9 3.2 43.3 23.0 16.6 34.6 31.5 23.8 25.3 23.6 27.8 25.0 23.1 24.6 24.1 24.6 24.5 25.0 24.1 13.9 9.6 11.7 32.7 27.6 20.4 22.3 21.6 23.3 11.4 26.5 22.2 101.9 7.2 15.6 11.0 16.7 41.5 18.6 9.1 25.4 20.5 2.2 16.1 21.8 17.2 16.2 36.8 43.9 17.3 48.2 18.8 17.9 12.1 7.6 29.3 15.7 34.8 24.8 10.1 38.4 21.0 8.2 28.6 13.3 4.4 19.0 15.0 10.6 30.0 31.4 15.3 17.5 38.7 51.1 14.9 15.3 25.2 16.8 13.5 10.7 28.8 12.6 13.2 13.1 18.2 17.6 10.3 18.7 32.3 17.6 28.9 21.2 30.4 31.4 14.8 MRPS31 IMOGN38 ENSG00000102738 "Mitochondrial ribosomal protein S31" Q92665 13 40729128-40771190 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 412.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039083, HPA046344" Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria Nucleoli "HPA039083: AB_2676340, HPA046344: AB_2679629" "unprognostic (9.62e-3)" "unprognostic (2.62e-1)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (1.04e-1)" "unprognostic (2.15e-2)" "unprognostic (5.96e-3)" "unprognostic (1.84e-3)" "unprognostic (2.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.72e-3)" "unprognostic (3.92e-2)" "unprognostic (3.13e-3)" "unprognostic (2.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.86e-2)" "unprognostic (2.54e-2)" 11.7 14.8 9.1 14.0 9.6 14.4 16.9 10.5 12.5 10.7 9.1 15.8 14.8 16.6 13.8 14.7 15.1 10.2 24.0 8.7 9.5 19.6 28.8 11.5 23.5 9.6 9.7 19.2 10.4 14.3 7.5 12.6 10.1 11.3 15.6 13.7 13.7 11.0 27.5 13.5 15.3 15.2 9.3 13.2 15.0 17.9 9.2 17.8 19.6 26.2 24.9 13.2 10.0 11.8 19.0 17.9 29.5 19.5 19.8 23.2 29.6 23.7 16.5 30.7 20.5 46.0 27.4 110.5 22.6 13.7 41.3 48.8 37.4 29.6 36.2 29.4 28.1 45.9 12.7 29.7 16.5 47.4 21.3 18.8 21.4 25.3 21.2 20.3 23.8 31.2 31.3 11.3 19.8 21.5 37.2 46.2 28.7 64.2 20.9 35.0 24.3 20.8 40.3 21.6 12.9 18.7 16.5 27.0 39.3 35.1 23.7 41.5 14.6 9.5 16.0 22.3 24.9 8.7 17.4 55.7 19.5 33.3 18.6 30.9 15.3 24.9 29.4 16.4 28.8 36.8 32.5 29.9 19.5 33.5 38.5 34.3 11.3 28.7 18.4 19.1 36.5 17.8 9.1 9.6 10.5 12.5 8.7 9.5 9.6 9.7 10.1 9.3 9.2 11.8 27.5 48.1 19.2 24.5 35.0 9.7 33.0 106.0 33.0 35.1 22.4 31.6 73.7 28.6 77.2 22.0 18.8 62.7 31.2 18.7 109.5 43.0 74.9 55.5 38.6 32.5 23.4 29.8 28.8 33.6 41.5 27.9 18.8 38.1 23.4 32.8 37.9 76.9 26.0 42.1 37.8 37.4 91.6 17.0 12.5 14.2 35.4 18.1 19.6 26.2 39.8 32.3 32.0 36.7 45.1 30.0 19.5 30.5 52.1 15.8 32.4 93.4 412.5 51.2 46.0 39.5 38.1 72.6 49.8 30.2 13.4 68.0 37.7 45.2 35.5 25.5 MRPS35 "MDS023, MRPS28" ENSG00000061794 "Mitochondrial ribosomal protein S35" P82673 12 27710822-27756295 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 242.6;Proximal tubular cells: 231.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038513 Supported Approved Mitochondria,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA038513: AB_10794084" "prognostic unfavorable (9.41e-4)" "unprognostic (8.35e-2)" "prognostic favorable (5.01e-4)" "unprognostic (2.59e-2)" "unprognostic (5.31e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (7.32e-2)" "unprognostic (2.12e-3)" "unprognostic (2.05e-1)" "unprognostic (3.24e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.51e-5)" "unprognostic (4.63e-2)" "unprognostic (2.44e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" 27.3 42.1 25.0 26.8 26.1 31.2 42.7 26.7 33.4 23.8 28.0 59.2 52.6 25.8 29.4 35.8 29.4 24.1 62.2 26.0 27.2 78.6 77.7 21.6 31.9 25.7 26.0 26.2 27.8 46.9 14.0 29.1 26.5 31.5 61.1 18.4 29.6 24.1 83.3 23.5 46.4 29.8 26.7 21.0 43.9 18.0 26.4 28.3 44.2 72.5 32.1 35.3 20.4 27.9 95.0 102.1 42.4 65.1 58.9 71.8 156.0 61.4 52.6 84.4 76.2 125.0 132.4 88.2 87.5 63.3 65.5 70.0 88.0 77.9 99.1 74.2 82.8 100.2 39.2 103.7 58.5 138.1 51.1 61.4 95.1 71.1 143.2 77.3 69.6 73.0 110.1 58.6 77.9 57.9 96.7 227.0 158.9 231.8 147.7 101.1 109.8 145.3 130.8 77.3 24.0 48.5 84.4 131.0 106.1 93.9 133.6 108.2 54.5 51.4 54.9 117.8 111.4 22.8 36.9 186.8 68.6 104.5 68.5 11.0 21.5 7.8 15.1 38.3 24.1 20.7 18.9 18.7 30.5 19.7 22.3 20.4 1.2 25.9 46.4 14.4 26.4 23.8 25.0 26.1 26.7 33.4 26.0 27.2 25.7 26.0 26.5 26.7 26.4 27.9 25.0 73.7 40.3 13.4 38.2 47.3 42.3 65.0 46.1 20.8 49.8 43.8 94.8 50.1 55.4 51.5 4.2 104.0 21.2 51.8 242.6 92.0 12.6 42.0 42.4 30.1 60.3 26.3 28.0 59.2 113.4 35.9 72.4 40.0 54.5 34.5 18.9 67.1 73.1 18.5 28.0 81.2 40.7 38.4 28.8 9.1 25.4 42.9 42.7 8.4 64.7 27.1 34.0 19.6 25.4 62.2 52.3 24.5 32.1 55.4 63.6 231.4 70.2 18.0 26.3 35.8 39.8 23.9 27.2 68.7 52.1 61.7 34.8 83.8 116.5 46.1 MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA043476: AB_2678498, HPA048479: AB_2680412" "unprognostic (8.10e-3)" "unprognostic (4.75e-3)" "unprognostic (3.69e-1)" "unprognostic (3.80e-3)" "unprognostic (5.25e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (3.78e-1)" "unprognostic (2.62e-3)" "unprognostic (4.62e-2)" "unprognostic (5.28e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" 17.2 33.5 21.4 17.9 22.7 24.6 23.3 24.1 26.5 18.3 25.7 29.8 29.5 20.7 19.2 23.8 24.2 13.4 64.1 21.4 23.3 32.7 31.8 15.4 24.7 24.0 22.8 30.8 24.2 32.8 19.6 12.9 24.3 23.4 33.3 22.3 23.3 21.6 98.6 21.9 23.4 19.8 22.7 18.5 25.9 33.5 22.8 30.8 21.4 97.0 27.1 20.2 17.9 25.1 68.2 28.9 59.4 55.1 30.6 31.5 69.6 42.6 40.6 66.2 59.2 155.0 46.4 70.6 41.1 33.9 68.9 59.8 118.0 62.1 69.9 44.0 77.5 69.7 42.4 94.4 51.0 52.2 29.9 37.9 41.5 54.6 45.4 38.3 51.6 84.8 101.5 35.9 45.7 54.9 70.6 68.6 93.9 57.4 62.6 88.9 50.9 98.3 83.2 47.3 51.4 30.9 49.4 71.5 59.9 58.0 58.9 52.2 34.0 38.8 78.2 38.9 46.6 32.6 41.5 56.3 33.6 79.1 33.3 21.7 23.8 10.1 39.3 31.5 43.3 44.4 43.0 41.7 43.0 35.3 42.9 42.4 2.8 46.0 39.9 32.1 49.9 31.7 21.4 22.7 24.1 26.5 21.4 23.3 24.0 22.8 24.3 22.7 22.8 25.1 18.2 22.4 28.2 28.1 21.0 19.5 25.3 56.4 22.2 24.7 15.4 22.2 110.2 22.8 30.4 22.0 12.5 39.9 29.1 17.7 107.6 40.7 51.7 35.9 18.6 22.5 19.7 47.5 43.4 42.7 40.7 21.2 18.8 12.9 22.8 34.6 18.2 31.2 28.8 8.4 54.2 27.9 24.4 15.2 9.9 14.6 23.9 15.9 30.2 17.8 26.2 21.2 29.9 49.3 69.4 22.6 18.3 27.1 25.0 17.4 23.1 72.3 42.1 32.0 39.5 24.8 28.1 112.8 40.7 23.4 13.2 20.4 25.2 62.9 40.5 19.0 MRRF RRF ENSG00000148187 "Mitochondrial ribosome recycling factor" Q96E11 9 122264603-122331337 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 210.0;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047177, HPA049987" Supported Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Microtubules, Cytokinetic bridge" "HPA047177: AB_2679970, HPA049987: AB_2680984" "unprognostic (8.38e-2)" "unprognostic (2.17e-1)" "unprognostic (6.40e-2)" "unprognostic (6.06e-3)" "unprognostic (3.64e-2)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.71e-2)" "unprognostic (1.89e-2)" "unprognostic (4.44e-2)" "unprognostic (2.98e-1)" "unprognostic (9.01e-2)" "prognostic favorable (2.14e-8)" "unprognostic (3.89e-2)" "unprognostic (4.05e-1)" "unprognostic (8.02e-2)" "unprognostic (8.88e-3)" 18.9 19.3 10.4 12.1 10.7 14.2 19.3 11.7 13.3 13.9 15.3 25.1 23.7 10.1 13.1 25.5 11.4 8.8 28.2 10.6 11.3 23.4 24.3 13.3 14.0 11.4 10.9 11.3 18.3 23.2 12.5 9.0 11.3 14.7 28.6 14.5 15.3 10.6 40.6 22.1 18.5 10.1 10.6 15.6 14.4 18.1 11.3 13.8 16.3 32.1 20.4 16.9 16.4 11.5 34.7 45.8 25.6 43.0 35.7 32.5 48.7 33.7 43.0 44.5 26.0 55.0 40.6 75.0 16.7 27.0 35.5 99.3 74.1 78.8 36.3 25.2 30.3 25.6 53.4 30.5 23.6 72.3 32.7 30.5 52.7 40.0 70.8 22.4 50.4 29.6 44.2 27.8 45.1 55.1 36.2 23.6 30.0 86.0 45.7 26.8 48.8 79.7 76.6 34.8 30.3 19.9 36.2 58.3 27.9 24.3 62.8 18.2 27.1 19.5 29.6 51.0 42.0 19.1 50.1 33.0 36.8 42.4 22.8 4.7 17.5 6.0 13.3 29.0 14.2 15.6 13.3 12.5 29.8 12.7 13.8 16.5 2.0 22.9 31.3 12.9 16.3 11.1 10.4 10.7 11.7 13.3 10.6 11.3 11.4 10.9 11.3 10.6 11.3 11.5 22.7 3.2 9.1 21.9 18.8 15.4 22.1 30.3 26.2 13.2 20.1 17.3 21.8 18.6 17.8 14.7 12.5 29.0 10.8 21.4 35.2 36.0 210.0 16.2 15.7 22.5 7.8 29.3 28.6 29.5 49.2 11.1 23.9 12.1 24.7 14.5 14.3 19.2 30.4 5.0 39.1 22.0 18.3 17.0 16.5 191.7 9.6 16.0 14.2 20.6 18.3 6.3 11.3 22.1 31.0 24.0 20.6 7.5 19.4 18.1 41.2 37.3 16.2 23.5 19.7 15.1 11.7 30.2 16.6 32.5 22.4 37.1 12.3 31.1 33.9 22.7 MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017642: AB_2669628" "unprognostic (2.12e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-3)" "prognostic unfavorable (5.32e-4)" "unprognostic (7.23e-2)" "unprognostic (8.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-3)" "prognostic favorable (5.14e-11)" "unprognostic (8.75e-2)" "unprognostic (2.94e-2)" "unprognostic (8.32e-2)" "unprognostic (2.53e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.55e-3)" 14.6 17.0 10.7 12.0 11.8 6.7 14.3 17.1 13.7 10.9 15.4 14.1 15.4 10.3 14.1 14.1 10.2 9.3 30.7 11.2 12.2 24.2 20.5 10.9 14.9 10.8 11.7 12.3 18.8 22.5 13.4 16.4 11.2 12.8 15.4 30.1 15.9 13.4 52.9 12.3 12.1 10.7 10.9 11.4 15.7 6.3 12.2 8.7 16.3 49.4 14.8 13.2 11.5 11.4 36.7 21.0 24.7 46.3 15.9 14.4 54.8 16.6 19.3 20.5 18.5 80.9 16.9 21.2 67.3 14.6 32.2 21.8 25.6 31.6 22.0 26.8 44.9 33.6 16.4 93.7 23.0 38.7 30.0 22.8 24.7 20.9 16.7 23.8 22.2 27.2 49.5 0.0 22.6 28.9 37.1 35.3 64.6 20.6 18.9 0.2 4.3 48.4 90.5 37.1 39.3 23.7 28.1 84.9 46.5 72.0 43.3 26.3 9.6 9.1 13.8 18.9 30.8 37.4 68.1 29.4 11.3 45.4 38.3 3.4 16.8 7.3 11.6 20.2 14.9 14.4 12.4 12.5 24.8 11.9 13.4 12.6 1.9 15.3 18.8 14.8 11.5 12.1 10.7 11.8 17.1 13.7 11.2 12.2 10.8 11.7 11.2 10.9 12.2 11.4 10.5 35.3 20.0 18.6 18.0 7.1 13.6 18.8 16.5 33.5 15.7 10.4 55.6 20.0 16.4 20.2 39.6 46.5 23.3 13.6 52.8 22.6 0.6 15.7 11.5 11.3 9.6 17.1 33.7 19.1 24.6 14.8 13.3 12.9 12.0 23.3 11.4 14.4 21.9 50.5 35.6 15.4 22.4 15.8 10.0 0.7 12.2 14.8 7.2 9.4 19.6 21.8 16.5 15.1 16.5 15.9 14.9 16.6 19.7 14.7 20.0 40.7 14.4 43.6 19.7 9.2 12.9 5.4 11.6 22.7 11.2 25.3 13.1 27.2 22.3 15.7 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006021: AB_2147687, HPA061422: AB_2684514" "unprognostic (2.91e-2)" "unprognostic (9.58e-2)" "unprognostic (1.52e-2)" "unprognostic (1.87e-3)" "unprognostic (8.86e-2)" "unprognostic (5.57e-2)" "unprognostic (9.76e-3)" "unprognostic (1.88e-1)" "unprognostic (6.85e-3)" "unprognostic (3.01e-2)" "unprognostic (6.58e-3)" "unprognostic (1.76e-1)" "unprognostic (3.98e-2)" "unprognostic (2.54e-2)" "unprognostic (1.66e-1)" "unprognostic (9.45e-3)" "unprognostic (1.33e-1)" 17.5 18.2 14.8 16.7 16.6 14.2 19.6 17.0 18.0 14.4 19.1 27.7 27.2 10.8 17.8 18.7 13.0 11.6 31.9 15.0 17.4 24.8 33.0 12.3 20.6 16.8 16.1 11.4 26.7 24.2 10.9 13.4 17.0 14.4 31.5 15.5 18.5 14.0 44.2 16.1 22.0 12.4 16.4 17.4 20.7 12.2 16.8 16.8 20.5 48.8 20.3 15.0 13.2 18.1 42.4 39.8 23.2 40.2 27.8 37.7 53.1 37.8 29.9 35.5 30.9 48.0 39.8 69.1 69.6 34.5 39.7 36.7 55.2 54.5 58.3 77.1 42.6 63.3 30.9 89.4 53.4 101.6 36.4 41.7 54.9 49.1 101.9 31.4 29.1 37.8 114.4 38.4 37.0 35.2 31.5 68.2 49.3 52.2 48.5 32.7 74.3 67.1 34.4 36.8 41.3 26.2 33.7 54.8 71.0 27.8 28.9 33.6 28.5 37.0 42.5 44.6 62.8 71.3 68.3 18.8 39.3 74.3 29.7 5.6 10.3 9.7 9.0 12.7 11.7 7.5 9.2 8.6 13.5 9.5 11.2 11.5 4.0 16.7 10.8 6.6 12.2 6.8 14.8 16.6 17.0 18.0 15.0 17.4 16.8 16.1 17.0 16.4 16.8 18.1 10.9 22.4 23.6 9.8 16.6 7.6 19.1 18.8 13.6 0.0 15.5 14.2 80.7 22.8 16.9 7.3 0.0 32.1 22.2 18.7 29.4 33.6 16.9 24.0 17.6 13.5 19.2 22.1 8.9 33.5 31.1 14.0 17.3 15.6 21.5 26.7 10.4 29.9 23.8 0.0 9.7 19.3 18.3 25.1 7.0 18.2 9.0 19.0 8.8 12.2 35.5 0.0 21.6 8.5 13.6 29.8 15.3 10.5 21.5 11.8 26.3 25.7 22.5 0.0 6.6 14.0 20.6 30.1 17.8 20.3 7.4 16.3 13.3 29.0 33.3 15.1 MTO1 ENSG00000135297 "Mitochondrial tRNA translation optimization 1" Q9Y2Z2 6 73461578-73509236 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030230, HPA030232" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA030230: AB_10598910, HPA030232: AB_10600891" "unprognostic (2.17e-2)" "unprognostic (5.29e-2)" "unprognostic (1.05e-2)" "unprognostic (3.22e-2)" "unprognostic (6.47e-2)" "unprognostic (8.58e-2)" "unprognostic (6.28e-2)" "unprognostic (5.48e-2)" "unprognostic (2.97e-1)" "unprognostic (2.12e-3)" "unprognostic (9.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (8.08e-3)" "unprognostic (1.64e-1)" 5.8 5.6 3.3 5.5 3.4 4.1 6.0 5.6 4.9 6.6 3.1 6.7 6.1 5.6 4.4 6.3 6.4 3.5 8.3 3.3 3.2 11.6 17.6 5.0 7.8 3.3 2.9 7.3 6.2 9.3 5.7 4.1 3.4 6.2 6.6 6.7 5.6 4.6 9.3 5.3 7.5 5.2 2.7 9.8 6.5 9.9 3.4 7.2 6.3 9.8 9.3 6.8 6.7 4.6 6.5 6.0 8.0 5.9 12.4 13.7 4.3 13.5 14.7 15.7 15.7 13.2 4.1 13.7 9.4 13.9 9.5 10.1 18.6 12.5 24.9 7.6 9.6 15.7 12.0 13.5 16.3 27.0 7.1 9.2 17.4 16.0 16.7 7.8 11.3 14.6 22.5 16.8 14.4 10.9 6.4 9.0 6.5 9.4 5.8 11.3 27.8 25.8 9.2 12.0 5.5 3.9 5.5 14.2 12.2 7.1 7.6 24.1 6.9 7.9 6.6 5.1 13.0 8.5 15.1 6.6 4.7 17.8 11.6 1.3 4.5 3.8 5.9 6.1 9.2 6.2 7.1 5.7 4.7 5.4 7.9 5.9 1.6 8.2 6.0 4.5 12.0 7.0 3.3 3.4 5.6 4.9 3.3 3.2 3.3 2.9 3.4 2.7 3.4 4.6 9.4 16.0 17.9 11.1 22.7 7.8 14.5 13.2 4.6 0.0 5.7 5.0 15.7 11.5 12.1 11.0 0.0 12.1 19.9 6.7 21.5 7.3 127.7 12.0 13.7 11.7 8.4 5.0 14.3 7.5 8.6 10.9 10.2 22.7 6.3 8.4 10.0 22.6 8.7 0.0 15.8 9.0 6.1 8.2 7.2 20.1 11.1 10.6 0.0 11.2 15.1 0.0 18.6 11.1 21.9 7.0 6.9 9.8 20.1 14.4 16.0 17.4 7.5 0.0 6.6 19.7 10.4 42.9 11.6 7.2 10.1 10.3 21.2 11.5 11.7 10.8 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795260-236921278 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.0;Glandular and luminal cells: 130.9;Inhibitory neurons: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA044474: AB_10966696, HPA054915: AB_2732589" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (8.10e-2)" 9.1 6.6 4.3 6.9 5.4 4.6 8.0 5.2 5.4 10.1 6.5 11.1 4.8 10.2 10.5 5.0 11.9 8.9 15.0 4.9 4.6 12.7 6.0 7.1 8.1 6.7 5.3 14.6 13.0 20.2 6.4 11.6 6.9 7.6 5.0 5.6 6.4 9.1 16.6 9.3 7.1 8.7 4.8 9.4 9.0 9.0 4.8 10.0 13.4 18.1 7.0 10.3 7.6 6.5 17.6 11.0 13.0 8.8 22.6 20.3 15.3 14.9 14.8 18.8 19.0 12.6 12.5 40.0 13.2 16.6 8.7 10.6 18.4 13.1 20.4 19.8 13.7 23.7 14.2 18.3 15.1 37.2 13.3 28.9 7.0 22.9 17.9 11.5 22.3 19.8 33.1 16.4 13.1 10.1 19.6 10.3 16.2 12.9 5.4 20.9 24.8 24.2 11.2 21.3 11.1 27.8 17.7 11.9 14.8 9.3 16.7 13.0 28.8 24.1 9.1 19.6 18.8 34.4 12.3 22.7 17.2 21.1 26.2 0.6 0.5 1.5 1.1 0.8 2.3 0.7 1.4 1.4 0.7 0.8 1.4 1.5 0.0 0.9 0.5 0.5 0.9 0.9 4.3 5.4 5.2 5.4 4.9 4.6 6.7 5.3 6.9 4.8 4.8 6.5 23.0 57.7 35.0 53.8 25.8 8.2 8.3 8.3 17.1 0.0 10.7 11.9 100.0 20.0 10.9 40.5 0.0 24.2 25.9 3.4 1.9 13.8 9.8 57.5 80.1 21.4 8.4 23.5 87.7 14.8 9.2 22.8 15.8 130.9 30.4 35.0 15.4 10.8 14.4 0.0 106.8 7.7 4.1 16.6 6.8 6.2 23.9 17.1 10.6 47.8 15.3 0.0 19.6 62.8 73.6 12.3 8.0 33.1 20.3 14.9 9.7 9.1 13.3 0.0 6.6 39.4 23.2 17.2 22.0 11.5 5.1 22.6 26.1 40.2 12.0 6.4 MTREX "Dob1, fSAP118, KIAA0052, Mtr4, SKIV2L2" ENSG00000039123 "Mtr4 exosome RNA helicase" P42285 5 55307989-55425579 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, mRNA processing, mRNA splicing, rRNA processing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 42.3;Endometrial stromal cells: 44.0;Exocrine glandular cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037379 Supported Supported Nucleoplasm NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA037379: AB_10601713" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (1.32e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.79e-2)" "unprognostic (5.08e-1)" "unprognostic (4.17e-2)" "unprognostic (1.46e-2)" "unprognostic (5.05e-2)" "unprognostic (7.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.09e-1)" "unprognostic (3.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" 20.4 22.7 10.2 21.9 11.5 18.5 22.0 17.4 12.7 22.5 14.4 17.7 24.6 22.1 14.1 19.1 17.8 19.8 24.3 9.7 11.2 20.8 19.6 16.7 25.9 11.1 10.8 20.1 21.2 26.6 17.2 18.9 11.5 21.6 19.9 17.8 18.9 14.7 29.9 20.8 24.1 13.8 11.4 19.2 20.9 23.4 10.3 21.9 25.8 22.5 21.8 21.0 19.8 14.9 40.9 49.2 38.4 39.9 32.8 35.0 49.5 33.4 28.3 39.7 50.1 57.1 51.2 79.3 37.4 33.1 52.9 28.5 76.8 50.3 59.9 14.2 53.2 51.6 45.4 45.9 31.3 33.4 44.8 27.5 31.3 42.9 51.6 33.6 35.1 29.7 60.9 45.0 37.9 35.8 32.3 36.5 38.4 16.8 46.6 39.5 44.1 33.9 41.3 56.9 42.0 28.8 40.4 24.5 35.4 42.4 52.5 44.8 33.2 10.0 27.5 28.4 62.0 31.5 33.6 59.0 27.0 69.5 40.8 3.6 5.0 5.4 7.2 4.7 6.9 6.1 5.7 6.8 6.4 6.4 6.1 6.2 1.3 4.5 7.9 6.7 5.6 4.1 10.2 11.5 17.4 12.7 9.7 11.2 11.1 10.8 11.5 11.4 10.3 14.9 27.6 32.1 42.3 0.0 10.1 0.0 0.0 0.0 0.0 0.0 22.3 13.8 0.0 0.0 21.7 20.2 0.0 25.0 24.6 0.0 11.7 32.0 0.0 28.2 44.0 10.0 0.0 0.0 0.0 40.7 21.5 16.2 0.0 26.2 25.2 30.8 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 13.9 0.0 0.0 0.0 0.0 35.7 0.0 0.0 8.3 0.0 0.0 22.3 26.2 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 34.9 11.6 31.7 0.0 0.0 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.1;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 11.2 10.6 5.1 9.5 11.2 5.7 6.3 10.1 10.9 7.2 3.4 8.3 8.9 11.7 12.3 9.3 9.6 11.8 14.4 6.5 9.0 18.7 19.4 13.1 11.1 10.9 10.4 11.4 11.9 12.8 6.7 10.8 10.6 9.0 10.1 19.2 10.5 7.1 28.9 9.1 10.2 12.0 8.2 6.7 6.7 7.1 9.3 7.5 9.0 32.9 10.6 14.4 5.5 20.0 19.3 18.1 10.2 20.0 34.0 13.6 25.1 31.1 18.5 16.5 15.4 27.8 15.1 32.6 27.9 24.6 27.4 11.8 17.0 14.2 27.9 22.9 15.8 14.6 62.0 15.3 21.9 23.4 6.8 18.3 11.4 24.6 18.4 20.4 10.4 8.0 21.9 24.2 9.8 4.2 14.2 11.7 7.3 29.4 19.0 12.4 9.5 14.1 16.2 16.0 14.0 2.5 51.6 33.7 28.6 18.1 10.7 17.5 14.6 31.9 19.7 24.1 22.7 34.7 13.5 27.3 23.1 50.5 19.1 5.3 4.0 3.0 4.1 5.5 7.0 3.3 6.5 5.7 3.6 3.3 4.1 3.6 0.1 3.1 4.4 2.3 9.1 3.3 5.1 11.2 10.1 10.9 6.5 9.0 10.9 10.4 10.6 8.2 9.3 20.0 7.7 16.0 70.1 10.1 11.1 16.3 9.4 4.6 12.0 0.0 9.7 5.1 12.9 5.7 9.0 9.2 0.0 9.9 11.4 11.0 21.5 10.2 50.1 10.0 10.7 8.0 9.6 12.4 25.4 5.5 8.9 11.8 9.2 6.7 10.2 6.5 8.6 19.3 7.7 0.0 20.8 9.1 0.0 11.1 9.4 99.2 10.5 9.7 1.8 15.0 8.1 0.0 7.2 20.1 50.9 7.2 6.0 11.7 26.5 14.3 8.7 28.9 10.1 0.0 6.6 10.7 10.1 17.4 13.1 10.5 20.6 11.2 13.8 11.8 9.4 8.7 NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N-alpha-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017310-20033655 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA063344: AB_2684991" "unprognostic (2.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (6.18e-2)" "unprognostic (9.30e-2)" "unprognostic (3.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" 50.4 53.3 38.9 34.8 40.6 46.5 65.3 41.6 51.6 40.8 54.0 41.9 27.9 41.7 54.2 113.5 41.6 32.6 61.7 40.2 42.9 85.2 82.5 40.2 37.3 40.9 41.3 33.0 62.7 103.9 26.7 53.0 41.9 43.5 42.8 49.6 47.1 46.9 84.9 38.2 33.9 46.2 42.3 31.8 42.1 66.6 41.5 37.1 59.7 73.6 51.0 51.3 44.1 44.5 212.7 139.9 50.1 69.4 95.0 116.6 67.7 149.2 100.3 132.1 123.8 67.0 137.7 108.4 80.6 113.6 125.5 156.3 85.8 233.2 153.2 51.4 75.7 79.4 49.6 132.6 141.2 102.2 65.9 122.4 182.1 132.8 153.9 93.2 139.7 80.4 126.7 115.7 157.6 177.2 128.6 149.9 37.9 181.5 180.7 69.8 191.9 148.3 190.0 70.4 84.1 62.2 81.9 254.1 170.7 42.5 145.4 171.1 113.7 106.6 75.4 137.8 153.8 130.0 171.9 116.9 66.5 76.2 76.7 39.7 86.2 70.1 55.5 97.5 83.6 63.3 65.9 65.4 92.9 56.6 63.5 75.0 12.5 70.3 81.8 77.7 75.6 100.6 38.9 40.6 41.6 51.6 40.2 42.9 40.9 41.3 41.9 42.3 41.5 44.5 60.5 67.3 42.2 17.0 44.9 108.7 113.6 312.4 45.5 52.9 62.9 75.2 73.1 77.2 147.8 104.8 25.0 111.8 51.4 32.6 230.9 194.0 399.9 99.5 87.6 77.4 41.3 28.8 18.0 169.0 102.2 66.4 31.1 75.8 51.3 46.5 50.3 72.9 255.9 69.0 22.7 43.8 164.8 66.8 56.1 60.5 69.9 68.6 71.2 31.9 100.1 91.5 58.7 16.1 25.2 198.0 37.1 74.9 44.2 184.5 45.7 242.6 199.9 60.7 39.5 75.8 90.8 354.2 58.3 122.5 118.8 85.5 40.8 99.5 54.2 141.7 NANP "C20orf147, dJ694B14.3, HDHD4, MGC26833" ENSG00000170191 "N-acetylneuraminic acid phosphatase" Q8TBE9 20 25612935-25624014 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050342 Uncertain Approved "Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA050342: AB_2681098" "unprognostic (8.72e-2)" "unprognostic (1.88e-1)" "unprognostic (7.42e-3)" "unprognostic (6.01e-2)" "unprognostic (5.59e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (9.01e-6)" "unprognostic (3.20e-1)" "unprognostic (3.75e-2)" "unprognostic (7.70e-3)" "unprognostic (1.24e-1)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-1)" "unprognostic (1.71e-2)" "unprognostic (9.42e-2)" 3.3 3.8 1.4 2.6 1.4 3.4 3.0 2.8 1.4 2.3 1.7 2.1 2.9 2.3 2.4 2.8 2.1 2.5 2.5 1.3 1.8 4.4 4.8 2.4 2.0 1.3 1.5 2.7 3.2 2.8 1.5 2.6 1.4 2.3 2.5 2.9 2.1 1.9 1.7 2.0 2.0 2.8 1.1 1.9 2.3 2.8 1.7 4.9 3.0 3.7 2.4 2.9 1.9 1.4 14.2 8.5 6.7 9.4 10.7 11.0 9.5 7.1 13.9 9.3 11.8 7.4 9.7 4.9 7.9 13.6 11.0 8.9 10.6 10.7 17.9 1.7 5.9 13.3 3.8 20.1 9.1 10.0 3.7 9.9 5.1 10.7 13.6 5.1 8.2 17.8 11.1 8.5 11.7 8.0 19.4 4.8 4.8 12.6 12.6 9.3 14.1 6.4 5.7 7.7 12.6 5.2 8.0 12.7 8.7 6.6 5.3 8.5 6.8 14.5 10.9 13.6 10.2 4.3 4.1 12.4 4.3 22.7 9.1 0.3 2.3 0.9 1.3 2.4 2.0 0.6 0.9 1.0 3.3 0.6 0.8 1.4 0.3 2.2 1.4 0.7 0.8 1.1 1.4 1.4 2.8 1.4 1.3 1.8 1.3 1.5 1.4 1.1 1.7 1.4 3.6 3.2 1.5 4.2 1.9 5.9 5.8 4.6 2.8 4.5 3.0 2.3 2.8 5.7 3.6 7.3 0.0 4.1 5.2 1.7 13.7 5.2 0.3 2.0 4.7 4.4 3.0 16.0 3.3 4.2 2.1 4.9 4.6 2.0 5.7 3.4 3.6 5.3 4.6 6.7 3.6 2.3 6.1 4.1 4.8 0.8 3.1 2.8 5.4 1.9 2.4 5.5 9.2 2.5 2.3 4.8 2.0 2.6 3.5 5.1 1.8 8.2 2.1 7.3 0.0 4.6 3.4 5.5 11.3 2.6 5.1 1.9 1.9 7.4 2.2 3.1 NARS1 NARS ENSG00000134440 "Asparaginyl-tRNA synthetase 1" O43776 18 57600656-57622213 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 221.3;Cytotrophoblasts: 116.0;Extravillous trophoblasts: 85.2;Hofbauer cells: 117.4;Syncytiotrophoblasts: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA 76000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB034257: AB_2151043, HPA040017: AB_2676801" "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 67.2 65.9 51.7 62.1 53.8 48.8 68.3 58.8 77.7 57.5 60.1 108.7 87.3 52.7 66.5 64.2 58.5 56.0 94.8 53.4 60.4 135.1 75.5 51.7 52.8 59.6 55.6 45.4 63.1 125.3 33.2 56.1 58.5 68.4 99.5 68.2 68.8 65.4 127.2 49.6 72.0 65.5 55.9 46.8 79.4 32.7 63.7 59.1 95.0 130.6 67.3 78.0 41.9 60.1 215.1 133.2 129.6 199.1 172.8 130.7 202.5 302.5 161.7 179.2 215.4 100.3 97.0 270.7 136.2 208.7 172.1 241.7 211.0 191.6 259.0 127.5 75.5 217.8 105.4 171.8 299.9 433.0 212.5 146.0 331.2 233.8 245.8 130.6 154.6 169.4 246.5 201.6 200.9 86.2 172.4 111.9 189.6 145.1 118.6 139.8 154.5 229.9 340.3 224.4 140.9 147.6 153.1 184.0 309.4 137.3 108.8 242.6 179.7 190.5 127.7 78.8 215.8 449.1 559.2 260.3 175.1 285.7 227.7 50.9 108.5 38.8 41.8 92.6 50.9 52.6 43.3 44.7 71.7 51.4 58.2 52.6 34.4 43.6 76.8 64.0 49.4 74.9 51.7 53.8 58.8 77.7 53.4 60.4 59.6 55.6 58.5 55.9 63.7 60.1 26.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.3 0.0 0.0 0.0 0.0 116.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 85.2 23.1 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 158.6 3.5 0.0 0.0 0.0 NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 60000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA020449: AB_1854327" "unprognostic (7.92e-3)" "unprognostic (1.24e-2)" "unprognostic (3.35e-2)" "unprognostic (8.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.12e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (5.06e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (2.41e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" 51.5 44.3 48.3 25.6 57.6 1.0 48.7 45.9 58.7 55.0 43.5 59.4 55.9 52.8 52.9 81.3 42.1 42.3 71.8 72.8 47.2 70.6 41.2 40.3 10.3 36.9 46.2 45.0 43.0 88.4 34.0 50.1 41.9 55.4 48.5 58.4 43.2 65.4 89.5 51.1 51.3 74.1 37.9 20.5 57.7 32.1 45.4 15.2 85.4 87.3 24.6 60.8 49.1 44.4 107.1 66.0 99.1 63.6 136.8 132.3 110.2 136.5 123.4 90.6 113.3 102.9 89.2 0.6 89.2 163.1 136.1 99.0 84.6 128.6 150.2 25.7 66.1 23.7 69.4 85.4 140.5 0.2 19.9 99.5 155.4 131.4 213.8 123.7 146.3 6.4 58.7 0.4 173.3 68.5 2.3 0.4 102.1 85.8 112.7 6.9 108.2 0.4 127.9 141.9 72.7 69.3 123.6 97.0 130.0 156.2 52.0 0.7 160.0 153.2 86.1 87.1 84.7 13.4 26.5 0.5 118.6 0.1 79.5 0.4 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 48.3 57.6 45.9 58.7 72.8 47.2 36.9 46.2 41.9 37.9 45.4 44.4 75.3 48.1 47.1 129.9 2.1 87.2 64.7 50.1 38.1 83.9 54.2 39.9 103.9 48.6 57.0 80.9 70.9 33.1 3.7 52.4 27.4 54.3 4.5 56.4 57.9 82.8 50.4 0.8 174.2 62.0 50.2 62.3 49.5 106.6 14.0 43.8 72.8 42.4 5.3 122.8 143.9 58.8 50.8 5.5 23.1 9.0 78.6 4.6 55.2 72.1 0.7 90.7 6.2 136.7 98.8 95.7 69.8 105.3 1.4 116.8 64.3 66.4 40.2 59.9 59.2 86.1 84.1 42.4 28.7 83.6 112.5 52.1 5.5 55.6 55.5 117.3 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 NDUFA6 "B14, CI-B14, LYRM6, NADHB14" ENSG00000184983 "NADH:ubiquinone oxidoreductase subunit A6" P56556 22 42085526-42090884 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1536.8;Distal tubular cells: 954.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 181.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (3.48e-2)" "prognostic favorable (3.87e-4)" "unprognostic (7.00e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (4.02e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-2)" "unprognostic (8.28e-2)" "unprognostic (3.61e-1)" "prognostic favorable (1.05e-6)" "unprognostic (2.15e-1)" "unprognostic (1.63e-1)" "unprognostic (9.49e-2)" "unprognostic (4.84e-2)" 9.8 30.9 14.3 19.2 13.1 25.9 28.0 13.9 18.9 9.6 19.1 37.6 12.5 15.7 21.3 38.5 8.8 10.9 124.2 13.4 15.0 37.3 51.4 15.4 20.6 14.9 13.7 9.3 31.2 109.2 17.8 25.2 16.1 17.8 57.6 19.8 28.2 18.8 115.1 12.4 38.1 14.2 12.9 18.0 30.7 22.2 15.0 3.7 20.3 101.5 11.9 24.0 9.3 13.1 48.1 1.9 4.5 44.2 94.6 78.9 6.3 0.3 0.3 0.8 1.0 54.1 99.2 0.7 1.4 67.4 2.3 47.9 1.2 1.2 4.5 0.4 0.7 1.0 10.2 181.7 0.9 55.3 73.1 28.1 27.7 57.0 102.2 1.6 33.9 2.0 73.9 94.1 1.6 90.8 35.6 3.7 34.5 134.6 138.7 60.2 48.6 0.3 1.3 6.0 1.0 31.8 96.4 56.5 143.4 6.0 113.2 0.6 0.0 2.3 110.2 41.9 72.6 41.5 64.0 4.5 35.8 95.8 98.9 127.4 109.8 123.4 78.2 114.0 84.8 111.8 106.0 72.9 156.5 85.3 88.4 88.2 37.7 98.6 99.4 99.3 109.0 213.5 14.3 13.1 13.9 18.9 13.4 15.0 14.9 13.7 16.1 12.9 15.0 13.1 103.3 60.9 94.1 15.7 103.8 185.7 228.5 445.8 76.8 58.7 105.7 132.8 1536.8 164.5 189.2 180.3 45.9 422.1 105.6 349.0 954.8 267.3 181.3 104.0 99.6 123.3 170.8 140.8 9.7 253.9 443.7 152.2 114.7 106.6 105.2 70.1 94.2 598.6 357.9 35.3 13.4 293.3 386.6 114.6 255.4 52.0 100.9 145.8 288.1 5.6 198.0 129.4 117.4 5.0 9.3 260.5 361.8 110.6 166.7 202.6 517.5 597.8 131.4 99.7 105.2 98.9 329.1 142.5 163.8 159.9 186.0 764.1 123.8 117.7 301.9 230.4 NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 241.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" 61.0 88.4 35.6 29.0 38.5 19.5 47.8 39.4 57.3 37.7 52.8 64.0 75.1 30.2 15.6 56.7 33.4 28.8 217.0 38.4 40.0 93.5 74.0 34.4 36.1 37.1 36.6 41.9 52.3 66.6 40.2 27.0 37.4 32.6 36.1 22.7 43.7 20.2 241.4 43.6 57.0 22.3 35.4 46.3 63.8 42.2 39.8 31.4 41.6 166.9 24.8 46.2 41.5 38.9 96.5 23.2 51.2 66.8 52.3 66.0 75.6 58.5 42.0 48.1 50.7 79.8 53.4 72.7 193.4 32.7 119.5 89.9 48.9 47.4 38.9 182.5 43.1 90.4 31.2 44.8 52.3 97.9 64.0 64.9 60.7 31.2 51.0 61.0 62.8 62.1 71.2 98.7 51.8 68.8 55.8 60.5 80.2 138.7 80.8 64.2 63.3 205.1 82.5 46.8 41.1 62.4 34.9 169.9 126.7 36.2 265.9 151.2 64.5 46.6 47.8 61.7 139.9 158.0 193.6 122.5 75.8 91.7 67.9 94.6 104.5 49.9 43.8 127.8 64.5 90.2 60.0 51.6 145.5 67.2 59.8 62.9 18.9 48.1 154.8 81.0 84.0 105.6 35.6 38.5 39.4 57.3 38.4 40.0 37.1 36.6 37.4 35.4 39.8 38.9 113.6 48.1 48.5 17.3 90.2 85.1 115.2 374.4 73.4 45.9 121.0 138.6 362.3 88.6 164.3 88.3 33.3 234.0 54.5 115.9 508.7 132.5 162.6 118.4 79.0 89.2 117.5 75.3 16.1 105.7 150.0 87.1 77.5 62.9 93.8 120.1 105.7 118.3 253.5 40.4 22.6 196.0 266.5 261.3 133.0 28.9 81.1 133.6 135.2 15.9 180.0 107.2 70.0 19.6 25.8 81.5 163.4 70.0 75.0 89.8 293.5 462.8 157.9 73.4 72.3 87.1 98.5 265.7 128.3 105.9 88.7 230.0 72.9 257.4 268.8 163.4 NDUFC2-KCTD14 ENSG00000259112 "NDUFC2-KCTD14 readthrough" E9PQ53 11 78016971-78079865 "Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Club cells: 1.3;Excitatory neurons: 4.0;Inhibitory neurons: 3.2;Melanocytes: 1.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.4;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 58.3;EFO-21: 47.1" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" 6.8 6.4 5.3 3.3 5.9 10.6 6.1 6.3 9.4 3.5 3.6 5.1 12.3 1.9 0.9 4.0 7.1 3.6 10.5 6.0 5.9 2.8 5.6 3.6 7.8 5.4 4.8 1.7 2.7 4.8 0.3 2.9 4.9 5.2 2.7 1.3 11.6 11.8 10.9 4.9 8.1 3.6 5.1 2.5 7.2 2.3 4.7 10.4 10.1 17.0 3.8 3.6 0.4 5.8 4.6 12.6 4.2 1.2 4.2 2.7 6.4 12.8 13.1 14.8 10.8 58.3 6.1 6.6 47.1 6.8 11.1 5.8 4.5 11.5 1.9 17.2 18.1 3.5 3.9 42.1 26.7 3.0 15.7 3.4 4.8 11.3 3.0 8.6 11.0 28.9 9.0 3.8 10.7 19.9 18.8 13.3 5.9 36.1 27.0 9.8 5.6 23.9 7.1 8.3 4.9 8.0 12.0 2.6 6.3 1.8 7.0 8.5 5.1 3.7 19.4 17.4 5.0 7.5 16.7 14.4 2.5 7.9 5.8 113.1 104.9 108.0 98.8 82.2 84.2 119.8 98.4 93.8 131.3 103.5 89.8 84.1 31.4 69.4 93.3 213.4 135.7 194.6 5.3 5.9 6.3 9.4 6.0 5.9 5.4 4.8 4.9 5.1 4.7 5.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.8 1.0 0.0 0.0 0.0 2.5 2.4 0.0 0.2 0.0 0.0 0.1 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 60.2 98.2 38.7 37.4 41.6 39.5 49.6 46.4 48.8 40.2 76.6 96.5 102.4 41.4 33.4 62.0 52.5 36.8 273.7 40.5 47.5 137.0 177.4 48.5 42.4 49.5 40.7 51.6 47.7 156.5 35.8 41.6 53.1 45.7 101.8 36.2 53.5 49.0 464.8 51.4 81.5 58.6 41.6 43.6 73.3 29.5 47.9 48.3 45.0 633.7 60.1 57.5 40.0 49.2 101.8 129.4 95.2 104.0 115.1 102.8 77.0 85.7 105.8 139.6 107.5 143.9 98.5 108.4 168.1 113.0 81.3 135.9 129.1 131.8 122.1 84.2 108.0 105.9 109.5 136.5 117.7 116.0 105.3 147.2 112.3 121.1 137.2 96.8 160.5 115.4 139.9 72.7 132.5 93.5 81.7 58.4 175.3 288.5 116.5 72.0 83.3 172.0 157.8 109.4 97.2 152.0 93.0 237.0 151.5 116.4 221.7 342.2 108.6 84.5 66.3 65.5 123.7 125.2 172.0 95.1 123.6 109.3 105.4 150.0 159.3 85.7 82.0 193.2 82.6 81.4 86.6 86.3 217.8 68.4 86.6 88.1 86.7 93.5 190.7 128.7 130.8 167.5 38.7 41.6 46.4 48.8 40.5 47.5 49.5 40.7 53.1 41.6 47.9 49.2 70.5 35.3 45.7 30.7 47.1 38.9 52.4 277.8 52.9 74.6 58.9 50.7 232.6 74.4 148.4 77.3 31.3 146.8 47.6 187.5 332.6 184.3 11.3 43.5 57.0 67.5 72.0 78.9 28.0 143.2 111.3 69.7 80.5 41.3 69.7 99.7 65.7 206.5 150.5 92.5 30.1 122.6 242.1 87.8 42.0 7.8 43.5 66.5 83.6 14.0 97.9 57.0 35.0 18.1 48.3 147.7 105.1 33.4 49.5 25.6 221.9 345.5 103.0 57.3 46.0 41.9 176.6 42.0 27.5 68.8 43.3 158.4 50.0 192.0 172.5 57.5 NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 397.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 553.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003884: AB_1079465" "unprognostic (1.25e-1)" "unprognostic (3.61e-3)" "unprognostic (3.44e-2)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (6.73e-3)" "unprognostic (6.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.93e-1)" "unprognostic (4.38e-1)" "unprognostic (1.72e-2)" "unprognostic (3.11e-1)" "prognostic favorable (3.85e-6)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" 94.2 80.6 71.3 37.0 71.8 50.9 99.9 75.1 101.8 82.0 70.6 93.2 83.6 65.0 68.6 80.6 69.5 50.2 190.5 70.3 78.3 137.2 147.9 55.7 45.7 72.3 70.4 101.7 45.4 125.8 58.2 63.0 73.8 65.9 89.6 59.1 63.6 73.6 346.2 76.7 71.9 72.2 75.3 42.9 80.7 37.9 75.1 59.8 74.0 397.4 60.7 71.3 73.0 77.7 118.8 102.9 200.5 119.1 133.9 192.7 167.9 140.7 136.6 153.0 185.8 126.7 151.4 83.9 180.2 121.1 146.3 85.3 72.0 167.9 175.4 77.4 137.2 57.8 97.1 115.6 142.4 141.0 95.8 161.2 190.2 105.8 184.8 167.7 135.1 93.4 50.2 88.5 141.9 110.5 106.7 116.9 60.9 45.3 115.1 126.4 113.1 166.2 165.1 113.0 92.7 99.5 96.4 92.5 175.2 106.8 148.2 145.2 104.4 93.6 98.9 68.7 186.9 67.6 91.5 102.1 99.7 202.7 137.3 19.4 83.9 7.9 49.1 101.8 55.3 72.7 61.9 58.0 121.6 50.3 68.2 70.0 6.8 79.4 108.3 93.8 72.4 68.2 71.3 71.8 75.1 101.8 70.3 78.3 72.3 70.4 73.8 75.3 75.1 77.7 62.1 38.5 56.6 49.0 52.6 125.8 150.4 382.0 56.3 44.8 100.0 119.1 328.4 82.9 170.6 84.6 41.7 168.4 43.2 124.5 553.7 174.1 61.5 65.5 87.7 84.6 90.4 47.1 55.9 167.3 163.3 113.1 47.9 68.7 76.0 146.9 99.2 137.8 144.3 30.3 73.2 135.3 215.7 76.4 127.3 61.5 157.5 70.4 117.4 38.4 161.4 113.6 63.8 52.8 68.4 179.4 153.4 152.7 38.4 95.3 188.7 425.9 112.2 76.0 124.9 145.1 173.4 76.8 75.0 79.3 101.4 179.9 50.0 96.4 171.2 158.2 NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 526.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 482.4;Proximal tubular cells: 499.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" 95.0 126.5 87.6 52.5 93.7 72.5 90.9 105.6 107.1 93.9 104.8 142.3 124.5 85.2 33.8 114.0 84.6 47.1 400.2 91.6 97.0 188.4 187.0 77.1 66.7 103.3 91.5 101.9 117.2 169.8 84.5 46.7 110.4 77.4 73.7 81.6 90.2 73.2 526.2 117.7 96.6 51.1 86.9 98.8 132.0 76.0 104.9 51.6 107.6 440.5 62.8 88.1 88.6 99.9 132.9 133.6 68.8 141.3 85.6 83.4 130.6 84.1 76.4 122.2 82.6 256.8 155.3 241.9 167.3 69.2 99.7 176.8 146.1 126.4 38.4 125.2 114.9 100.0 189.1 127.9 119.0 136.9 106.9 126.7 119.0 100.4 88.0 76.9 109.3 173.9 180.9 192.6 75.8 190.2 163.1 268.0 68.5 295.3 168.8 184.5 135.8 399.1 99.3 95.3 109.9 104.6 104.3 347.4 275.3 46.0 177.4 138.0 90.7 118.9 88.8 172.3 87.5 187.7 116.8 122.6 138.0 144.6 117.7 39.0 72.8 38.1 65.1 83.4 71.6 59.8 55.0 63.2 110.7 60.1 50.2 63.7 13.1 104.0 51.2 73.0 78.1 77.0 87.6 93.7 105.6 107.1 91.6 97.0 103.3 91.5 110.4 86.9 104.9 99.9 54.6 60.9 75.0 33.3 76.2 80.3 95.9 187.6 77.4 68.7 82.1 94.4 482.4 61.5 120.7 86.5 50.1 203.5 72.8 235.7 397.2 114.9 74.0 43.1 47.5 56.7 98.5 85.0 32.9 112.1 158.8 82.4 137.1 55.2 61.4 99.6 56.4 136.2 136.5 63.9 36.5 155.9 152.5 68.8 81.4 222.7 65.6 68.4 113.8 13.1 81.0 89.3 60.8 19.1 34.6 70.1 122.8 59.0 146.6 55.0 199.4 499.2 80.3 78.5 46.0 90.8 136.9 100.7 83.3 127.0 80.6 189.1 79.3 145.9 274.8 111.7 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 97.4 171.6 94.3 69.2 97.4 149.8 101.7 106.8 139.7 63.9 106.0 124.2 102.3 69.7 91.1 142.6 64.0 68.7 419.3 96.7 106.0 180.7 404.2 88.6 105.0 105.9 104.4 52.4 111.6 136.7 72.1 73.7 105.9 88.5 119.8 129.9 97.4 72.4 606.9 94.7 100.5 80.6 103.7 86.4 133.8 79.6 102.7 90.2 72.7 538.3 105.1 122.1 76.5 104.6 136.5 139.8 159.1 148.4 116.6 164.0 133.4 165.4 266.5 217.7 205.5 265.1 109.4 209.4 149.5 158.6 200.3 66.9 157.5 175.5 208.8 104.6 136.6 133.0 135.3 364.8 133.6 373.8 159.2 139.2 144.3 134.9 146.2 156.8 239.3 184.3 216.5 644.0 204.6 171.6 263.5 328.9 131.4 750.5 172.3 124.5 118.2 794.2 354.3 218.7 167.0 122.3 164.6 188.0 220.3 113.6 174.2 282.8 145.8 273.4 194.3 198.8 223.0 180.4 292.3 237.1 195.4 166.0 181.0 250.8 161.8 194.2 118.1 196.1 148.3 237.6 176.9 140.5 237.9 201.1 153.5 142.7 76.0 124.2 187.9 315.1 231.9 231.8 94.3 97.4 106.8 139.7 96.7 106.0 105.9 104.4 105.9 103.7 102.7 104.6 107.3 80.1 145.8 17.6 143.1 148.0 319.0 629.4 159.4 101.2 165.0 167.3 69.9 178.7 339.5 150.8 87.6 344.1 146.6 211.0 876.5 415.2 271.5 160.3 108.2 117.3 106.5 165.4 32.9 531.4 323.3 122.0 144.3 183.9 120.3 109.7 96.4 351.5 313.5 94.2 37.3 201.7 480.1 115.7 267.1 186.2 122.1 170.2 231.3 17.8 293.2 167.1 96.8 32.2 46.5 530.3 201.2 102.0 244.9 554.3 349.9 810.6 293.4 184.2 105.2 124.0 196.3 217.4 175.0 226.5 147.6 289.4 165.7 266.7 227.3 469.0 NFX1 "MGC20369, NFX2, TEG-42, Tex42" ENSG00000086102 "Nuclear transcription factor, X-box binding 1" Q12986 9 33290512-33371157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056310, HPA061382, HPA073519" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA056310: AB_2683097, HPA061382: AB_2684496, HPA073519: AB_2686614" "unprognostic (3.90e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-2)" "unprognostic (1.40e-1)" "unprognostic (3.07e-2)" "unprognostic (2.02e-2)" "unprognostic (9.11e-2)" "unprognostic (1.81e-2)" "unprognostic (8.71e-2)" "prognostic favorable (3.75e-4)" "unprognostic (3.40e-2)" "unprognostic (1.27e-1)" "unprognostic (1.13e-3)" "unprognostic (3.36e-2)" "unprognostic (1.14e-2)" "unprognostic (9.62e-2)" "unprognostic (3.20e-2)" 16.8 16.8 13.7 15.6 14.5 21.9 20.6 20.4 17.6 15.5 15.9 17.1 16.9 17.4 15.7 18.3 15.4 12.4 23.4 13.8 15.0 14.6 27.7 16.0 22.3 13.7 12.8 21.9 15.8 23.4 13.5 13.5 13.5 16.5 19.1 19.4 17.9 16.0 37.7 25.5 17.5 15.7 10.9 18.2 15.8 12.2 14.0 26.3 22.9 26.5 25.2 16.8 15.7 18.2 29.8 24.0 21.4 20.3 31.3 35.1 21.5 27.6 27.4 30.6 30.5 21.7 11.9 46.0 17.0 32.0 20.5 16.3 38.8 29.8 28.4 33.9 18.9 24.1 58.2 24.5 38.1 43.3 25.6 32.7 48.9 26.1 65.4 27.3 18.9 25.6 37.6 38.3 32.2 20.9 28.3 40.7 34.7 21.9 26.8 30.0 23.3 25.2 20.7 28.1 29.3 20.6 27.5 29.3 15.9 25.1 17.0 42.7 23.8 24.8 20.6 18.1 30.4 20.4 19.9 44.6 27.3 21.5 14.4 35.9 5.5 10.4 9.8 8.9 10.5 13.0 10.7 10.8 9.0 10.3 11.8 11.9 3.5 9.3 7.4 15.4 7.6 6.7 13.7 14.5 20.4 17.6 13.8 15.0 13.7 12.8 13.5 10.9 14.0 18.2 16.0 60.9 42.5 35.3 41.9 8.4 24.6 12.5 21.6 29.3 13.2 13.5 36.9 22.8 35.4 27.6 54.2 12.5 17.2 20.6 7.9 16.1 65.9 16.7 19.0 14.9 9.1 25.2 59.7 13.2 11.8 18.5 26.5 19.8 18.9 15.7 17.5 32.4 15.0 21.9 59.0 23.9 12.2 19.4 10.2 17.0 18.3 19.0 3.6 47.8 16.4 13.7 16.5 37.7 55.0 12.4 21.6 23.0 47.1 25.3 23.3 8.2 43.7 32.2 13.1 27.3 17.5 16.1 14.8 20.9 11.2 18.1 20.9 19.2 16.7 21.0 NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 9800000 "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA036335: AB_10696654, HPA036336: AB_2675068, HPA061466: AB_2684532" "unprognostic (6.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (9.52e-5)" "unprognostic (2.48e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.51e-6)" "unprognostic (1.94e-1)" "unprognostic (8.53e-3)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.65e-2)" "unprognostic (6.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-3)" "unprognostic (8.61e-2)" 13.2 19.2 14.1 15.2 15.8 11.0 24.3 15.7 23.8 17.7 13.7 21.8 16.5 15.9 26.3 16.7 22.5 13.2 21.5 14.9 14.8 24.3 22.9 15.6 26.5 15.3 13.8 21.4 15.5 27.0 9.7 19.1 16.2 17.2 28.0 32.7 19.8 19.8 23.5 21.6 15.7 19.1 15.6 18.1 20.1 18.5 14.1 26.5 19.4 30.6 32.4 17.1 12.7 17.5 39.5 42.1 66.9 41.3 29.8 37.1 45.9 42.6 45.4 88.6 71.3 66.1 44.7 31.8 40.2 36.5 64.1 42.7 96.8 56.0 94.6 42.4 90.8 47.4 73.6 70.9 27.0 56.8 31.3 31.7 52.3 58.6 55.8 39.9 29.9 65.6 70.2 31.4 52.7 51.4 69.9 71.1 79.1 44.7 73.5 41.1 37.1 61.6 46.8 40.6 42.3 49.5 36.6 36.8 51.9 94.4 36.5 50.5 15.6 42.2 39.8 38.3 39.0 28.4 58.3 68.4 41.4 45.6 41.6 70.1 23.0 30.7 27.8 34.9 29.1 31.4 31.8 35.3 28.8 23.7 35.4 29.1 7.8 33.6 31.1 29.8 32.0 24.2 14.1 15.8 15.7 23.8 14.9 14.8 15.3 13.8 16.2 15.6 14.1 17.5 6.0 0.0 7.0 2.6 11.7 3.7 7.7 43.1 12.5 90.5 6.9 9.3 13.9 10.0 26.5 5.5 14.6 34.3 8.0 7.5 15.6 20.3 16.2 10.2 9.3 7.0 1.8 23.2 6.2 18.2 35.6 9.8 9.7 7.8 9.5 12.7 6.8 9.3 17.2 18.5 5.7 10.5 26.4 7.3 2.2 6.5 16.1 9.5 5.4 5.6 17.2 18.8 8.2 2.5 5.7 13.2 9.2 19.2 23.9 6.3 10.1 21.3 24.9 27.4 6.6 7.2 14.5 30.9 24.4 12.9 8.2 22.6 10.0 11.1 11.4 6.2 NKIRAS2 "DKFZP434N1526, kappaB-Ras2, KBRAS2" ENSG00000168256 "NFKB inhibitor interacting Ras like 2" Q9NYR9 17 42011382-42025644 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062861 Approved Nucleoplasm,Nucleoli NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA062861: AB_2684884" "unprognostic (2.53e-1)" "unprognostic (1.09e-3)" "unprognostic (2.31e-2)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (9.37e-3)" "unprognostic (2.89e-2)" "unprognostic (2.56e-1)" "unprognostic (6.96e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.76e-1)" "unprognostic (2.70e-1)" "unprognostic (3.25e-2)" "unprognostic (5.42e-3)" 21.7 15.7 14.1 20.8 17.1 25.6 18.4 15.3 15.4 18.8 15.6 20.8 15.2 19.0 11.0 32.7 14.4 17.8 45.8 14.3 12.0 16.9 19.3 16.7 17.8 14.8 13.3 16.0 13.3 19.4 10.8 33.9 13.1 16.1 16.3 13.7 16.2 18.0 50.0 26.6 16.2 26.4 12.1 15.1 16.9 20.8 15.5 22.1 13.5 36.8 19.0 20.8 20.1 15.0 22.4 42.5 57.4 31.1 39.8 26.8 33.7 36.4 28.1 56.6 41.6 43.6 31.3 37.4 57.3 38.6 38.4 47.1 47.3 28.6 29.6 30.6 54.2 32.9 37.1 33.0 62.8 45.8 25.9 41.0 50.8 38.1 29.8 38.6 71.3 47.8 47.1 36.9 33.8 23.7 87.3 30.4 34.4 30.0 30.0 67.9 63.7 35.8 40.3 23.2 68.5 90.0 26.6 84.0 38.6 55.6 51.5 55.5 50.3 36.2 38.8 40.5 41.5 47.4 82.7 30.0 24.6 27.5 52.2 54.5 54.2 46.1 14.2 45.1 14.1 15.4 14.2 14.4 43.5 17.1 14.4 14.0 30.7 27.0 50.0 48.4 13.4 25.2 14.1 17.1 15.3 15.4 14.3 12.0 14.8 13.3 13.1 12.1 15.5 15.0 26.6 16.0 10.3 3.9 19.0 17.0 18.7 27.2 12.5 21.0 19.9 17.1 26.3 10.0 23.8 16.5 20.9 52.3 13.8 19.1 21.5 30.0 27.8 11.9 18.5 27.1 19.2 21.2 5.4 28.1 39.7 20.1 11.2 16.3 14.0 28.1 19.2 15.6 37.9 23.5 4.8 17.5 42.7 31.1 29.1 6.6 19.6 27.8 10.6 5.6 37.2 24.7 14.4 1.5 4.5 30.4 14.7 18.4 13.3 20.8 20.9 19.0 10.9 26.6 6.6 15.3 24.5 34.7 41.3 21.0 25.7 62.3 12.8 23.3 15.2 21.6 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NR1D2 "BD73, EAR-1r, Hs.37288, HZF2, REVERBB, REVERBbeta, RVR" ENSG00000174738 "Nuclear receptor subfamily 1 group D member 2" Q14995 3 23945286-23980617 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053868, HPA054798" Approved Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA053868: AB_2682284, HPA054798: AB_2616453" "unprognostic (8.64e-2)" "unprognostic (9.96e-3)" "unprognostic (2.27e-1)" "unprognostic (2.46e-1)" "unprognostic (8.67e-2)" "unprognostic (2.09e-2)" "unprognostic (2.04e-1)" "unprognostic (3.61e-2)" "unprognostic (2.60e-1)" "unprognostic (6.79e-3)" "unprognostic (2.21e-1)" "unprognostic (5.73e-2)" "prognostic favorable (4.47e-7)" "unprognostic (2.36e-3)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" 15.4 16.0 14.1 10.9 13.7 15.3 20.9 26.8 21.5 13.7 8.7 13.7 13.6 24.9 13.8 15.8 16.8 14.5 31.7 14.2 14.8 21.8 29.5 14.1 14.7 13.1 15.2 31.2 17.0 52.8 11.9 8.7 13.7 17.5 11.3 34.4 32.4 24.7 54.5 14.0 13.9 13.3 13.7 18.7 14.8 7.4 17.3 12.2 54.2 50.4 14.2 10.6 12.4 18.8 22.5 5.0 11.5 10.9 11.8 12.6 7.1 32.7 42.7 17.8 19.7 3.7 21.6 16.0 10.7 46.0 27.8 14.7 14.6 21.4 36.9 5.8 16.9 2.6 11.3 4.5 24.6 8.6 2.3 16.9 22.1 21.7 55.4 32.9 12.3 9.3 5.8 56.3 14.2 12.9 4.7 2.7 12.5 18.2 24.8 4.1 18.6 11.1 9.9 30.6 11.8 26.2 23.9 13.6 29.2 18.5 11.9 7.4 24.5 46.2 47.0 30.2 37.6 27.4 39.4 7.4 26.3 12.6 27.5 0.0 0.3 0.0 1.4 1.1 2.6 1.0 1.6 1.3 0.4 0.7 1.1 1.1 0.1 0.5 0.6 0.4 1.0 0.4 14.1 13.7 26.8 21.5 14.2 14.8 13.1 15.2 13.7 13.7 17.3 18.8 51.8 12.8 7.5 51.6 39.6 33.3 34.7 14.5 59.2 82.5 29.7 23.9 39.5 17.2 17.5 20.2 39.6 11.1 43.0 17.1 7.9 11.3 10.0 77.5 49.8 38.9 28.5 3.8 58.6 15.1 2.5 47.7 35.7 135.2 8.2 33.2 15.4 33.1 9.6 95.9 62.0 18.2 26.4 12.8 32.0 11.3 34.2 26.8 28.4 32.8 12.6 62.8 11.3 44.2 57.5 19.8 10.3 42.5 28.5 41.4 17.9 11.9 16.0 53.6 32.9 46.8 45.5 7.6 10.9 42.0 33.5 6.8 44.4 37.0 12.1 31.1 NUBP1 "CIAO5, NBP1, NBP35" ENSG00000103274 "Nucleotide binding protein 1" P53384 16 10743786-10769351 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041656, HPA041799" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA041656: AB_10960278, HPA041799: AB_10960692" "unprognostic (2.51e-2)" "prognostic favorable (2.81e-5)" "unprognostic (4.01e-3)" "unprognostic (1.66e-3)" "unprognostic (2.81e-1)" "unprognostic (7.04e-2)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (8.28e-2)" "unprognostic (5.08e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "prognostic favorable (7.61e-8)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (8.23e-2)" "unprognostic (1.69e-2)" 22.7 39.3 12.6 25.9 12.7 31.0 22.0 13.6 16.5 19.9 15.2 27.4 21.6 21.3 24.8 19.7 25.6 19.6 46.7 12.5 13.1 27.8 31.1 21.2 31.1 13.2 12.7 22.9 31.9 30.3 17.0 19.6 13.1 21.1 20.0 12.0 21.7 21.0 37.7 15.7 22.1 22.7 13.5 28.5 28.7 17.3 12.9 21.4 23.5 34.7 36.9 24.4 16.8 13.8 31.3 55.9 37.2 23.1 16.8 31.0 35.5 29.9 27.9 51.4 42.6 49.0 33.2 53.7 60.5 36.7 40.0 33.5 34.9 30.7 38.2 84.8 43.9 30.3 39.3 80.4 33.7 27.7 34.3 29.2 23.0 35.2 19.2 28.6 34.2 20.6 43.3 31.7 38.3 72.0 18.2 40.2 46.1 25.5 29.9 72.5 48.2 58.6 37.0 37.7 22.9 33.5 51.8 38.6 29.2 23.7 39.3 30.2 30.5 40.0 40.8 49.9 38.2 56.0 52.0 42.4 36.7 55.3 48.0 3.8 82.7 41.3 39.2 88.2 35.9 75.6 34.7 39.1 89.7 69.3 29.9 31.1 9.7 35.2 66.7 44.0 46.5 52.9 12.6 12.7 13.6 16.5 12.5 13.1 13.2 12.7 13.1 13.5 12.9 13.8 20.3 6.4 23.1 3.9 33.7 14.3 26.6 39.8 10.8 17.0 14.9 17.3 6.0 34.3 32.2 23.9 6.2 49.6 19.0 12.3 66.5 54.2 2.4 17.3 12.2 21.3 16.8 12.0 8.4 79.1 29.2 16.7 15.8 17.2 24.1 17.3 14.6 29.6 56.4 6.7 8.1 19.2 40.7 38.4 91.2 3.6 25.7 38.0 16.0 3.7 72.7 30.1 20.6 3.0 5.2 48.7 18.4 19.5 17.6 17.9 27.2 65.0 31.6 18.5 6.6 20.0 15.9 33.1 29.4 12.3 11.9 60.7 17.8 25.3 18.0 29.2 NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 68.2;Inhibitory neurons: 74.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" 9.7 6.4 4.2 3.9 4.6 1.8 8.9 4.5 4.8 4.9 4.2 7.6 4.9 5.8 7.6 4.6 6.4 5.3 17.0 4.0 5.0 12.2 12.3 4.1 5.7 4.9 4.7 6.8 5.5 7.9 3.8 5.5 4.5 6.3 7.8 5.2 11.9 6.1 11.9 4.7 5.8 5.4 4.3 6.6 4.7 3.5 5.0 5.5 8.0 17.4 5.4 4.2 3.2 5.8 13.6 8.5 6.4 3.3 8.9 16.4 11.5 7.3 8.2 8.9 10.2 5.9 15.3 9.8 9.2 9.1 7.5 11.7 8.6 15.5 15.3 7.1 11.1 3.5 6.3 30.4 8.8 10.4 3.0 10.7 17.0 6.0 12.8 7.3 5.0 7.0 6.4 4.9 9.8 7.4 7.7 7.1 5.4 10.8 13.1 8.6 13.4 5.3 10.2 10.0 6.0 6.2 12.2 10.8 14.5 7.2 21.1 5.4 4.9 8.6 5.9 5.6 6.8 8.1 9.7 9.3 5.5 7.3 7.9 0.0 1.1 0.4 2.1 1.2 1.7 2.6 2.7 2.3 4.4 1.7 3.0 2.4 0.4 2.5 0.7 2.2 1.8 0.9 4.2 4.6 4.5 4.8 4.0 5.0 4.9 4.7 4.5 4.3 5.0 5.8 6.9 12.8 9.8 68.2 10.1 9.6 8.6 5.4 9.1 15.3 10.2 7.1 36.9 15.7 10.6 9.2 20.9 11.2 7.5 6.3 7.9 6.8 24.1 12.6 10.8 6.3 7.2 6.7 48.2 5.7 10.2 12.0 7.1 5.4 14.5 16.4 4.6 15.3 4.9 10.1 74.8 12.0 2.0 4.1 16.1 7.4 6.5 6.1 12.4 54.4 2.8 16.2 5.2 87.9 99.6 5.2 5.8 11.7 8.0 4.4 5.1 19.1 18.7 28.4 13.1 11.8 9.8 15.7 5.2 7.3 11.6 5.7 6.4 23.1 18.2 5.9 NUDT13 DKFZp586P2219 ENSG00000166321 "Nudix hydrolase 13" Q86X67 10 73110375-73131828 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040636 Approved NA No "Cluster 24: B-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA040636: AB_10960360" "unprognostic (3.75e-1)" "unprognostic (3.85e-1)" "unprognostic (1.07e-1)" "unprognostic (2.48e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (2.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-1)" "unprognostic (9.40e-2)" "unprognostic (5.07e-4)" "unprognostic (1.91e-1)" "unprognostic (3.82e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (5.96e-2)" 1.9 3.2 1.4 1.9 1.7 2.4 2.0 3.4 2.0 1.7 1.3 2.6 2.9 1.7 3.9 1.6 1.9 1.8 4.3 1.6 1.3 4.3 6.2 1.5 2.4 1.4 1.4 1.8 3.1 3.0 1.7 1.5 1.8 2.0 1.8 2.9 2.1 1.0 4.2 3.0 2.5 1.1 1.0 2.5 2.9 2.4 1.8 1.5 1.9 2.1 1.5 2.4 1.7 2.2 4.7 3.3 5.3 6.6 3.2 2.7 1.1 4.1 3.6 2.1 2.3 8.7 9.6 2.3 2.0 2.5 3.4 5.4 0.5 3.8 2.1 1.7 9.3 6.4 5.9 4.9 0.3 3.5 2.5 2.0 4.1 2.7 1.5 5.6 1.6 4.1 5.5 3.5 2.1 2.2 2.1 5.0 2.0 3.0 10.5 4.7 0.9 0.1 2.9 2.1 2.3 3.4 2.0 5.4 1.9 2.2 3.0 2.3 3.1 1.8 7.1 0.7 1.6 2.5 3.1 3.1 5.0 6.5 1.7 0.0 1.1 1.1 0.7 1.1 0.8 1.3 0.5 0.6 0.8 3.7 0.9 1.0 0.4 2.2 1.6 0.3 1.7 0.4 1.4 1.7 3.4 2.0 1.6 1.3 1.4 1.4 1.8 1.0 1.8 2.2 1.9 6.4 2.0 2.6 1.9 0.9 1.9 2.8 0.6 1.1 1.6 1.7 6.2 1.5 2.2 3.7 4.2 3.6 0.4 1.1 3.9 1.8 5.5 2.9 1.3 1.8 1.2 1.3 4.7 0.7 0.9 1.1 1.5 2.7 0.0 1.8 0.4 3.7 1.7 0.0 5.1 1.7 2.0 2.9 1.0 5.0 0.9 1.8 0.0 5.6 2.8 0.9 2.1 4.5 8.1 1.6 3.3 0.7 0.7 1.2 2.5 6.2 5.3 1.9 0.0 2.3 1.4 2.9 0.9 1.4 1.4 1.1 0.8 2.3 1.3 1.1 OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" 64.9 67.4 35.0 39.2 39.4 32.1 32.0 42.8 45.4 33.8 119.6 56.3 95.6 40.9 16.6 61.6 34.0 26.9 324.0 34.4 50.6 89.7 39.8 43.4 40.0 44.6 44.4 24.8 27.5 99.9 34.9 33.1 44.2 37.9 41.5 25.9 43.0 46.9 363.6 56.4 87.5 51.0 35.7 39.0 52.5 36.2 43.6 32.1 54.9 374.7 41.5 42.5 37.7 35.6 35.8 73.5 42.2 66.0 63.4 69.8 41.9 54.2 51.3 59.5 50.9 67.2 71.7 156.0 63.0 79.2 119.2 108.2 85.7 81.4 58.4 92.0 22.8 47.4 140.6 33.5 32.8 59.4 51.2 66.0 60.5 85.4 60.9 43.0 82.4 50.7 55.8 45.4 63.7 50.1 59.2 34.1 39.8 97.7 81.8 55.9 30.1 175.9 68.5 104.4 73.2 35.0 78.8 107.6 34.4 75.8 64.2 58.7 66.4 43.4 38.5 76.3 64.0 40.9 84.0 85.9 78.4 65.7 80.4 9.9 21.8 12.6 17.9 28.5 19.5 11.1 20.7 18.1 22.0 9.3 8.5 10.8 12.2 19.3 35.4 10.8 42.1 23.2 35.0 39.4 42.8 45.4 34.4 50.6 44.6 44.4 44.2 35.7 43.6 35.6 19.6 6.4 22.5 49.3 23.1 19.5 12.3 15.9 22.8 21.4 14.4 18.2 114.3 12.8 14.2 47.8 18.8 24.0 20.0 64.5 31.3 14.9 51.0 26.1 15.6 16.0 23.4 32.0 43.3 16.9 16.4 20.6 35.2 38.9 21.5 15.5 17.9 22.6 33.8 62.2 53.1 32.6 12.2 24.5 43.4 24.5 11.8 33.8 21.4 29.0 22.7 14.3 16.5 22.1 36.6 20.9 38.0 17.3 27.8 16.4 82.0 51.8 17.0 24.0 19.7 24.7 20.2 10.6 19.9 28.1 26.3 36.7 27.7 30.3 33.5 18.1 OLA1 "GTPBP9, PTD004" ENSG00000138430 "Obg like ATPase 1" Q9NTK5 2 174072447-174248599 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035790, HPA041443" Approved Enhanced Cytosol NA NA 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA035790: AB_10601977, HPA041443: AB_2677483" "unprognostic (3.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.23e-2)" "unprognostic (2.85e-3)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.73e-8)" "unprognostic (6.51e-3)" "unprognostic (7.66e-2)" "unprognostic (1.09e-2)" "unprognostic (3.50e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-3)" "unprognostic (4.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.62e-2)" "unprognostic (9.75e-2)" 42.2 44.3 39.7 38.2 42.7 53.7 57.3 42.5 48.9 34.3 30.0 48.0 50.1 34.7 38.8 58.1 38.0 35.1 57.4 44.5 43.8 56.4 43.0 23.5 47.9 38.0 36.6 31.1 56.3 44.1 27.4 42.0 40.1 41.1 52.7 42.5 36.3 33.6 105.6 52.0 45.7 37.0 38.0 24.6 35.2 48.8 40.7 58.3 59.7 93.1 53.3 48.3 31.0 39.1 181.4 84.1 134.9 225.5 70.1 152.2 243.0 142.1 142.8 194.2 147.1 200.9 104.4 246.5 138.9 114.5 143.9 139.9 165.3 164.6 227.3 113.7 142.5 231.3 76.4 209.9 135.3 264.3 90.2 134.8 200.6 206.3 217.4 177.4 174.5 88.0 256.8 82.3 170.3 116.6 241.4 272.9 159.1 193.9 273.0 180.4 217.8 170.7 245.1 192.0 218.3 124.7 96.8 141.6 206.2 142.2 101.2 220.6 127.5 127.1 161.4 128.5 210.8 76.2 207.3 190.5 124.6 180.0 115.4 18.1 24.9 7.4 16.2 24.2 23.4 17.9 18.6 20.8 37.1 16.4 21.5 21.2 2.1 26.1 20.0 22.5 25.3 22.7 39.7 42.7 42.5 48.9 44.5 43.8 38.0 36.6 40.1 38.0 40.7 39.1 43.2 35.3 33.0 57.5 49.0 62.7 73.5 92.4 76.8 47.3 86.0 83.8 68.3 47.1 57.0 31.3 35.5 153.7 47.7 44.6 103.7 145.1 267.8 37.1 55.2 47.8 70.7 92.5 132.6 105.3 112.8 53.0 60.1 43.1 41.2 73.3 29.3 25.8 97.3 33.7 129.8 79.6 65.1 59.6 54.4 99.5 40.4 55.9 32.0 65.6 83.1 60.3 52.5 101.6 101.8 112.8 51.8 51.1 56.3 84.2 78.4 141.7 36.1 35.9 26.3 69.7 92.3 104.8 35.9 113.7 64.1 105.9 55.9 94.6 107.6 79.3 OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527427-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA044881: AB_10964052" "unprognostic (3.37e-1)" "unprognostic (3.89e-2)" "unprognostic (2.66e-1)" "unprognostic (5.71e-3)" "unprognostic (1.24e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (3.14e-3)" "unprognostic (4.53e-2)" "unprognostic (8.06e-3)" "unprognostic (1.72e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.30e-12)" "unprognostic (5.85e-2)" "unprognostic (1.94e-1)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" 4.8 7.2 3.3 4.7 3.4 4.0 3.5 4.4 5.2 3.0 3.7 4.6 4.0 4.9 3.0 5.8 3.4 3.3 10.5 3.2 3.1 7.4 7.8 4.4 4.7 4.9 4.0 3.4 4.4 12.0 6.0 4.4 5.0 3.8 3.9 6.4 4.0 4.1 11.1 5.8 5.0 4.7 2.5 5.8 4.9 8.9 5.5 4.6 4.6 12.9 4.7 4.1 3.5 3.2 15.2 18.9 7.4 7.3 4.8 5.9 11.3 9.7 8.9 10.1 10.7 8.8 10.5 13.0 6.9 9.8 11.5 12.0 12.5 13.3 8.9 24.0 12.6 20.1 10.8 9.1 8.8 14.1 25.0 8.9 10.1 11.2 12.2 5.8 7.3 7.6 17.5 14.2 6.9 9.3 11.3 5.8 6.5 12.6 12.9 10.9 6.7 7.1 8.0 26.9 5.5 6.6 12.4 11.3 5.2 6.6 6.3 8.0 15.9 8.5 9.7 7.1 16.7 9.5 19.1 10.6 8.2 10.1 13.1 5.6 5.3 2.9 3.6 7.8 3.6 4.4 3.2 3.1 5.6 3.9 3.9 4.0 4.7 7.8 10.5 5.1 4.8 3.6 3.3 3.4 4.4 5.2 3.2 3.1 4.9 4.0 5.0 2.5 5.5 3.2 11.0 12.8 11.7 8.5 23.0 18.7 22.4 14.6 13.1 22.8 9.2 7.9 25.4 17.2 11.6 11.0 52.1 25.6 15.7 18.8 25.4 18.4 18.5 12.8 13.8 15.2 13.8 5.7 9.5 21.1 29.8 10.6 14.3 20.1 15.9 8.9 11.4 21.9 16.3 20.2 10.2 14.5 16.2 11.4 28.3 20.2 6.2 17.4 14.2 4.7 19.0 15.1 11.3 3.0 8.1 18.2 19.2 6.4 11.9 15.8 21.2 16.8 10.7 36.0 0.0 23.3 23.6 23.9 13.1 11.2 19.6 36.3 14.4 19.5 16.6 16.7 OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: AB_2676401, HPA043625: AB_2678587" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "prognostic favorable (2.08e-5)" "unprognostic (7.80e-3)" "unprognostic (7.32e-2)" "unprognostic (2.79e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (7.42e-2)" "unprognostic (1.42e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.08e-7)" "unprognostic (1.25e-1)" "unprognostic (9.00e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" 19.6 41.7 14.1 15.5 15.2 27.2 27.4 15.3 18.9 24.7 18.4 26.8 29.4 20.0 31.6 19.6 22.4 19.5 25.5 15.0 15.6 42.8 57.6 18.5 17.8 15.4 16.7 22.4 37.3 44.9 16.1 22.9 16.7 25.9 28.3 15.9 30.1 27.0 57.7 26.6 25.5 21.2 14.0 15.6 27.8 18.0 15.7 24.0 32.3 43.8 23.7 19.6 17.1 15.1 40.9 33.6 24.7 33.2 56.5 52.4 26.8 32.9 42.3 38.4 34.4 38.1 40.2 41.1 42.7 37.9 47.2 41.4 45.4 43.5 43.0 40.0 20.9 28.1 25.1 25.8 60.2 36.2 52.9 40.4 52.8 36.2 94.4 40.0 41.7 38.3 48.6 37.3 34.5 19.0 34.0 26.2 28.0 59.5 32.7 32.5 39.8 28.6 45.6 47.0 28.5 20.3 38.6 47.7 46.0 33.6 66.9 22.7 45.8 32.7 22.8 49.5 22.3 51.9 45.2 41.4 37.0 25.6 26.8 1.7 1.6 1.5 2.8 1.4 2.6 2.2 2.9 2.3 1.6 1.6 2.6 2.1 1.5 2.2 1.3 4.0 1.3 1.1 14.1 15.2 15.3 18.9 15.0 15.6 15.4 16.7 16.7 14.0 15.7 15.1 29.2 25.6 9.0 14.7 18.9 39.6 16.4 13.7 29.6 23.8 38.0 27.1 34.1 32.9 19.0 27.6 22.9 14.2 31.1 34.0 7.9 14.0 8.8 37.9 52.7 21.8 30.0 10.5 25.6 18.6 14.7 21.1 22.4 43.8 27.9 21.8 15.4 67.1 16.0 26.9 22.9 40.0 8.2 12.9 16.9 14.5 15.8 17.9 14.2 12.2 9.6 15.7 18.6 18.1 23.3 20.2 20.5 19.9 32.2 31.2 34.6 21.0 27.8 21.7 6.6 28.4 19.3 25.1 14.5 27.0 47.3 30.8 20.0 43.5 28.4 26.4 OSBPL9 ENSG00000117859 "Oxysterol binding protein like 9" Q96SU4 1 51577179-51798427 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027378, HPA027397" Supported Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA027378: AB_1854816, HPA027397: AB_1854817" "unprognostic (5.99e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-2)" "unprognostic (2.43e-3)" "unprognostic (3.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-1)" "unprognostic (4.17e-3)" "unprognostic (1.58e-1)" "unprognostic (8.36e-3)" "unprognostic (8.61e-2)" "unprognostic (3.64e-2)" "unprognostic (7.53e-3)" "unprognostic (2.55e-1)" "unprognostic (4.95e-2)" "unprognostic (3.37e-1)" 27.5 38.1 17.9 18.1 23.8 30.1 32.6 26.3 23.5 25.5 28.3 20.8 17.4 31.1 31.0 17.7 23.3 17.6 37.0 17.6 23.9 42.8 60.8 27.5 25.9 25.0 21.8 30.5 33.3 60.0 21.1 21.8 26.6 27.8 19.1 53.5 22.0 22.4 70.0 19.6 21.7 24.2 23.0 27.2 34.3 28.4 22.2 21.8 24.7 35.2 33.0 23.7 24.7 32.2 66.3 31.7 69.0 11.2 38.1 17.9 90.7 30.1 50.8 54.9 60.0 53.0 46.6 105.8 54.4 34.1 120.9 26.9 59.2 57.4 76.9 71.9 41.9 77.4 62.7 104.7 36.9 81.7 35.5 44.7 55.0 56.8 31.4 66.8 68.9 52.1 154.4 31.1 26.7 45.4 20.3 92.5 97.0 26.8 15.1 58.2 102.8 110.5 74.0 47.4 31.8 45.2 22.4 79.6 93.7 154.7 38.0 82.8 22.9 11.6 51.2 17.2 58.1 80.2 52.5 120.4 39.3 32.8 23.0 52.7 12.2 30.5 20.1 9.9 28.9 32.6 19.7 20.8 25.0 23.9 21.0 22.2 16.9 16.3 9.4 23.2 20.5 16.4 17.9 23.8 26.3 23.5 17.6 23.9 25.0 21.8 26.6 23.0 22.2 32.2 32.5 80.1 56.8 75.4 39.2 17.7 33.8 25.7 34.1 102.0 34.2 33.0 47.9 38.6 50.5 46.0 41.7 89.2 30.4 20.5 125.2 47.6 40.7 36.3 46.3 30.1 29.8 35.7 64.8 47.8 50.2 48.6 54.0 52.9 33.6 75.7 18.2 61.7 40.1 26.9 113.0 18.3 38.7 22.7 16.0 38.3 62.4 25.3 65.8 63.7 50.1 43.8 29.9 62.8 216.4 41.9 14.3 50.0 81.4 38.5 26.4 59.7 32.1 35.3 46.0 36.9 62.9 32.3 18.9 26.9 18.9 75.5 32.0 52.2 21.2 27.4 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favorable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 3.9 8.2 3.6 3.5 5.0 1.9 7.2 6.1 5.0 4.5 3.0 3.5 3.3 5.7 5.6 4.0 5.2 3.2 8.9 3.4 4.0 8.4 7.9 3.9 6.5 4.3 4.5 8.7 3.1 4.7 2.7 4.0 4.5 4.1 3.9 9.8 4.7 3.7 12.3 6.1 3.5 5.0 4.3 5.4 3.1 6.4 3.9 5.6 5.2 11.0 6.3 3.6 3.0 6.1 7.1 3.8 16.7 12.7 12.9 7.1 9.8 10.8 7.5 14.9 15.9 4.5 7.1 4.7 11.7 4.5 8.2 10.1 15.0 12.7 16.9 12.3 11.5 15.3 9.0 5.9 6.7 8.8 7.6 7.8 10.6 11.5 5.5 10.2 11.3 11.8 5.6 7.2 9.8 3.9 6.8 9.9 8.1 9.5 17.4 7.5 13.4 8.1 9.7 3.8 10.1 11.2 7.3 12.8 23.9 20.6 10.1 9.9 4.7 9.6 8.5 14.3 6.8 7.3 6.6 7.4 12.7 11.0 10.7 0.5 2.7 2.3 7.5 2.7 10.6 7.7 7.7 8.6 3.8 9.8 11.3 10.5 0.4 7.6 2.4 6.6 6.6 3.1 3.6 5.0 6.1 5.0 3.4 4.0 4.3 4.5 4.5 4.3 3.9 6.1 3.6 6.4 3.6 6.8 8.4 1.9 2.8 5.9 5.2 8.9 4.0 4.8 8.6 8.6 2.8 0.0 12.5 10.6 7.3 0.4 7.9 3.0 1.4 3.5 5.5 4.1 0.0 5.2 6.6 2.3 7.3 4.5 1.5 2.3 3.8 6.8 3.6 2.9 4.4 10.1 10.0 1.1 2.0 2.4 1.7 0.8 11.1 4.1 1.8 5.6 1.8 12.0 13.4 10.1 17.0 2.0 1.0 8.2 1.9 1.1 1.7 10.2 6.0 11.8 26.3 5.8 8.4 9.6 13.7 4.4 2.0 2.2 6.0 11.8 2.2 1.0 OXA1L "MGC133129, OXA1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 32: Non-specific - Translation" Mitochondria "HPA003531: AB_1079539" "unprognostic (4.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (7.25e-2)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "prognostic favorable (4.82e-4)" "unprognostic (8.35e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (1.15e-3)" 77.7 90.7 27.6 40.8 28.5 71.9 67.6 31.4 28.8 59.4 47.1 72.9 66.3 55.0 48.1 76.6 55.8 49.6 147.2 27.5 29.6 70.8 108.6 54.8 70.0 31.3 29.1 71.2 98.0 105.3 27.5 38.0 31.1 45.0 57.7 41.9 64.2 44.8 234.9 69.3 58.9 46.1 29.1 62.3 83.9 25.0 31.6 63.6 54.9 272.5 75.5 61.3 60.4 31.1 89.3 121.3 48.8 82.1 146.7 217.4 94.4 64.0 138.1 94.3 107.9 91.1 96.4 167.0 86.4 75.0 73.0 121.0 103.0 126.3 90.0 67.6 65.4 79.1 73.2 329.7 165.5 150.9 88.4 211.0 137.6 75.4 114.9 114.7 273.3 93.8 62.2 124.0 103.4 130.0 91.8 51.3 53.2 118.5 150.0 92.9 87.2 128.3 117.9 103.4 35.1 67.0 94.6 205.7 129.7 58.4 89.2 122.7 86.2 52.7 62.2 98.5 75.4 94.0 84.7 78.1 41.6 83.6 60.0 11.9 68.1 18.5 29.5 71.6 36.0 51.0 42.5 37.4 95.1 54.4 47.4 35.6 15.1 41.7 58.5 26.9 55.8 53.7 27.6 28.5 31.4 28.8 27.5 29.6 31.3 29.1 31.1 29.1 31.6 31.1 30.6 48.1 44.0 7.8 83.7 69.5 61.1 89.0 92.8 31.0 52.1 46.5 118.0 72.9 62.1 29.5 10.4 72.8 32.5 48.9 74.3 85.2 10.2 20.4 40.3 58.6 40.7 64.3 6.8 161.3 113.0 47.6 66.8 23.1 80.4 56.5 64.2 102.9 143.4 18.5 7.5 75.3 38.7 148.1 76.8 13.3 57.2 85.6 51.6 3.7 133.4 22.9 74.2 4.5 8.0 86.3 69.7 36.9 84.2 45.6 101.4 116.0 42.6 38.3 39.5 39.4 43.0 31.8 28.4 112.9 67.3 57.2 57.9 70.6 112.1 74.9 OXSM "CEM1, FASN2D, FLJ20604, KS" ENSG00000151093 "3-oxoacyl-ACP synthase, mitochondrial" Q9NWU1 3 25782917-25794534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 59.5;Spermatocytes: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021293, HPA021300, HPA021337" Enhanced Approved Mitochondria,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA021293: AB_1848772, HPA021300: AB_1848774, HPA021337: AB_1848776" "unprognostic (2.20e-2)" "unprognostic (3.28e-1)" "prognostic favorable (1.35e-4)" "prognostic favorable (5.51e-4)" "unprognostic (1.01e-1)" "unprognostic (8.17e-2)" "unprognostic (2.15e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "unprognostic (2.83e-2)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.18e-9)" "unprognostic (1.79e-2)" "unprognostic (2.42e-1)" "unprognostic (3.10e-1)" "unprognostic (1.73e-2)" 6.1 11.0 3.1 5.5 3.4 4.0 9.3 3.5 4.6 4.9 5.3 11.1 9.4 4.6 13.9 8.5 6.8 3.9 12.9 3.3 3.6 13.7 22.0 4.9 7.9 3.3 3.3 4.9 10.5 10.0 5.8 5.9 3.4 5.9 12.3 10.2 10.1 5.9 14.6 7.7 7.8 5.2 3.5 7.9 8.2 11.7 3.5 7.1 8.6 15.6 8.8 5.5 5.3 3.4 11.0 18.1 3.8 10.5 10.7 11.6 10.9 8.6 12.4 15.8 11.2 13.8 12.9 20.4 11.5 8.0 9.2 11.3 15.7 16.6 14.9 12.3 16.0 22.5 15.2 16.9 13.1 18.4 13.7 11.0 20.4 12.7 13.3 10.3 13.8 18.9 23.5 16.0 13.7 16.6 13.6 14.4 0.7 8.8 20.6 17.8 9.9 33.7 23.3 6.8 5.4 9.7 13.8 23.6 18.3 6.0 25.5 16.9 8.5 10.0 11.9 13.1 12.7 15.1 18.8 6.6 13.9 16.0 10.4 2.1 5.1 3.7 8.6 6.0 10.1 7.9 8.8 10.8 8.4 8.9 10.2 10.7 0.8 11.4 6.8 8.8 6.0 6.3 3.1 3.4 3.5 4.6 3.3 3.6 3.3 3.3 3.4 3.5 3.5 3.4 5.9 0.0 9.4 3.9 9.3 3.1 5.9 23.0 4.0 6.5 8.7 13.2 13.3 10.0 12.0 11.0 4.2 19.5 7.1 5.4 11.7 13.5 59.5 7.8 7.2 4.9 2.4 2.1 4.5 6.8 16.9 5.9 4.6 6.4 10.1 13.0 7.5 17.4 8.5 5.0 5.1 9.8 14.2 3.8 3.2 15.1 7.2 6.8 5.4 1.0 5.2 9.1 6.2 3.5 3.8 7.5 8.9 4.1 7.8 6.5 10.6 18.4 9.2 7.4 0.0 5.3 5.8 48.0 12.6 7.2 4.4 14.1 5.9 19.2 8.8 3.6 PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 60000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "HPA073653: AB_2732234, HPA076187: AB_2686784" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (5.37e-2)" "unprognostic (2.65e-2)" "unprognostic (1.62e-2)" "unprognostic (4.74e-2)" "unprognostic (1.13e-3)" "unprognostic (2.98e-1)" "unprognostic (3.17e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (3.54e-1)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" 69.5 54.3 47.8 36.6 50.8 56.6 67.4 52.0 64.2 65.1 52.0 57.1 43.3 61.6 57.3 52.0 51.2 53.3 92.5 51.2 52.0 78.0 90.9 50.3 39.4 49.5 49.5 53.7 54.8 74.3 29.3 68.1 50.8 69.1 54.8 95.2 51.3 68.5 155.3 31.1 40.2 65.3 54.3 34.2 46.9 83.6 49.0 47.6 73.6 122.9 45.3 70.1 39.9 56.5 94.5 82.2 158.0 153.7 161.8 127.1 129.1 81.2 180.0 151.5 130.9 77.2 112.8 62.5 136.9 115.5 227.3 60.4 249.3 98.0 153.5 52.2 96.7 49.2 157.1 122.6 142.3 74.2 74.3 135.8 186.1 102.5 191.7 153.1 146.8 45.9 115.9 82.1 153.0 101.7 82.4 101.8 78.5 89.4 104.8 63.8 119.2 88.1 188.8 114.3 89.4 135.3 260.3 99.2 190.0 144.0 141.4 106.3 82.4 136.6 112.5 68.8 103.7 61.7 112.6 94.3 79.7 113.1 120.4 40.4 24.1 46.2 18.9 20.7 25.2 26.4 23.2 26.2 23.7 26.7 28.9 23.2 8.6 24.9 22.5 66.8 23.0 22.1 47.8 50.8 52.0 64.2 51.2 52.0 49.5 49.5 50.8 54.3 49.0 56.5 66.4 32.1 52.2 15.0 39.4 73.3 74.0 78.5 52.3 48.8 78.8 53.1 122.4 78.6 52.7 44.1 20.9 76.3 66.0 33.1 158.5 120.3 182.6 73.8 56.4 71.2 44.9 54.9 30.0 91.6 89.2 64.2 39.3 55.9 24.6 47.4 50.0 49.2 59.4 35.3 25.3 52.1 103.7 40.9 39.7 58.0 76.4 42.0 83.6 20.6 53.8 86.6 24.7 26.7 35.1 116.4 43.8 66.5 43.3 106.4 45.1 148.8 40.9 67.7 26.3 70.2 71.4 171.2 76.6 56.0 66.3 68.1 35.1 49.7 47.7 84.3 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: AB_2682014" "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 5.3 6.5 3.7 6.2 3.8 3.2 7.1 7.5 4.8 6.1 1.4 7.3 8.8 6.1 4.7 7.0 5.8 5.4 8.5 4.0 4.3 12.7 6.9 5.2 9.1 3.6 3.2 5.4 4.0 8.9 4.3 7.7 4.0 6.7 7.8 5.8 5.3 6.3 12.0 7.3 7.0 6.3 3.0 6.9 6.4 7.8 3.7 9.1 6.7 9.0 9.0 6.2 5.2 4.3 15.3 9.5 20.0 17.8 11.2 13.6 14.9 13.6 17.2 17.0 16.1 9.8 15.2 10.5 10.7 13.3 7.8 17.7 17.3 10.2 19.8 15.5 16.6 11.6 7.7 13.2 13.8 16.5 8.9 8.4 21.0 12.3 22.4 13.4 10.6 14.0 18.8 11.1 14.9 9.2 18.0 20.0 22.4 10.5 26.8 21.1 20.7 13.9 16.1 8.4 16.0 19.7 10.6 21.6 17.1 21.2 23.8 10.9 10.0 11.5 12.4 11.8 15.9 10.4 16.2 21.9 18.9 18.8 8.8 6.1 2.5 1.4 2.3 2.2 3.2 3.0 3.0 2.8 2.7 2.9 3.7 3.5 1.3 3.9 3.5 2.9 2.8 2.3 3.7 3.8 7.5 4.8 4.0 4.3 3.6 3.2 4.0 3.0 3.7 4.3 8.2 9.6 15.3 22.2 12.2 6.1 5.2 4.3 12.0 13.9 9.5 7.4 28.6 14.3 9.2 12.9 27.1 7.7 8.9 10.4 9.8 7.3 6.1 17.7 14.8 11.1 6.6 12.8 42.5 6.5 6.2 12.0 11.2 11.8 14.5 17.0 6.8 13.6 9.7 5.0 37.9 10.0 2.0 12.0 4.3 4.6 7.5 11.6 3.6 35.6 12.4 7.3 24.7 26.7 41.4 8.1 3.7 8.2 9.9 5.3 8.7 40.3 21.5 20.7 0.0 11.3 12.0 17.1 13.3 13.8 6.0 4.7 12.0 20.0 11.2 4.4 PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 202.1" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7;Late spermatids: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 120000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 34.4 75.1 23.3 15.2 33.6 37.9 27.5 31.4 29.3 17.5 35.5 43.6 38.1 13.8 13.9 26.3 19.2 17.0 94.6 23.6 28.5 88.9 202.1 14.8 16.2 31.1 29.4 12.1 32.0 57.0 15.6 19.6 30.4 23.7 41.9 17.2 23.6 21.7 83.8 15.1 27.5 22.6 27.1 12.7 26.1 38.8 29.8 21.1 37.9 91.4 20.7 20.5 11.4 47.8 64.8 45.8 42.4 64.4 30.2 34.5 75.4 33.0 35.5 49.1 69.6 67.9 44.7 80.3 89.4 46.6 44.0 35.1 50.3 44.0 69.4 47.8 43.0 140.8 49.5 101.4 66.4 107.3 60.2 40.8 41.4 31.0 69.4 30.5 56.1 131.6 104.5 41.0 38.0 123.1 109.3 63.1 36.0 96.8 40.9 29.3 34.6 116.6 89.9 69.4 84.0 62.9 84.4 48.9 77.5 35.2 98.3 62.9 42.0 24.5 26.0 69.2 29.6 78.3 70.0 66.9 34.9 41.7 29.9 7.3 29.5 7.5 22.6 30.8 25.4 21.7 14.7 23.2 44.6 19.8 15.1 18.7 2.7 25.9 28.7 38.5 14.8 22.6 23.3 33.6 31.4 29.3 23.6 28.5 31.1 29.4 30.4 27.1 29.8 47.8 5.6 9.6 14.0 16.0 9.2 4.1 9.4 37.9 3.4 16.0 12.5 5.3 51.1 8.6 28.4 20.2 10.4 57.1 8.0 15.1 39.2 24.6 316.7 14.1 9.5 8.1 9.1 53.2 16.5 14.0 27.1 13.6 14.8 14.1 29.2 18.1 9.3 76.3 35.1 11.8 22.7 15.1 24.4 11.7 5.2 159.0 13.7 11.4 19.6 16.9 16.5 11.8 10.3 22.1 50.9 14.4 16.7 10.9 22.6 10.4 19.2 97.3 23.6 13.2 13.1 13.6 13.1 11.3 29.0 16.2 3.3 50.9 9.9 52.8 25.1 12.2 PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA025696: AB_1855077, HPA061444: AB_2684519" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.73e-3)" "unprognostic (2.58e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (8.38e-2)" "unprognostic (3.73e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (3.11e-3)" "unprognostic (3.11e-3)" 36.5 35.2 18.2 23.3 20.2 16.8 38.2 25.2 21.9 33.8 23.2 38.8 25.9 35.3 47.5 28.0 30.8 29.0 35.5 16.4 19.9 38.3 30.4 28.3 28.8 19.1 19.2 42.6 73.9 77.9 25.5 26.3 19.9 36.1 25.8 25.4 57.6 32.0 83.4 33.5 26.8 28.3 18.9 46.3 29.5 14.9 18.9 35.1 53.3 67.1 27.3 32.6 31.0 21.6 11.7 5.7 24.3 5.4 34.1 28.4 14.0 13.4 22.8 5.5 9.0 3.1 23.6 12.0 18.0 17.3 8.4 27.2 4.7 15.8 9.3 11.9 8.5 12.6 11.7 8.3 43.9 5.2 12.4 30.4 31.7 6.9 17.4 35.8 24.4 16.0 9.5 36.0 12.0 4.2 24.5 13.7 8.9 16.7 3.0 8.0 4.5 13.8 24.7 21.7 16.2 15.0 10.9 14.8 17.1 18.5 14.2 7.6 22.2 6.8 5.9 8.8 5.2 21.6 15.6 3.9 16.4 11.4 7.0 18.7 8.4 23.2 8.6 11.0 10.4 13.1 11.5 9.4 8.1 13.0 13.5 12.4 29.4 21.6 12.7 14.7 13.2 9.1 18.2 20.2 25.2 21.9 16.4 19.9 19.1 19.2 19.9 18.9 18.9 21.6 98.4 115.4 68.1 78.7 78.1 54.0 66.0 49.7 58.6 80.7 66.7 61.0 92.7 48.6 52.0 84.6 10.4 38.1 80.7 28.7 64.6 32.9 4.7 66.6 63.9 79.3 46.7 51.4 144.7 39.8 37.2 79.2 45.9 92.2 53.0 107.2 76.4 37.1 25.1 58.9 159.7 39.0 61.1 51.8 56.8 10.4 104.1 62.7 71.2 144.3 52.5 120.8 55.6 106.1 122.3 43.8 32.2 120.0 101.8 98.0 45.5 92.8 56.7 24.0 39.5 73.2 68.2 16.4 24.2 38.3 59.2 68.5 62.1 87.6 30.9 94.6 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 31.4 24.4 15.2 30.0 16.0 45.3 21.0 16.6 15.8 16.7 17.8 25.7 60.3 19.1 13.9 31.0 15.6 20.7 46.4 15.5 21.1 18.3 20.7 22.5 22.9 18.8 18.0 15.8 16.8 22.7 12.9 20.1 18.5 16.6 22.9 14.4 19.3 18.6 73.8 43.0 49.1 23.0 17.5 25.9 24.2 22.4 18.1 18.1 17.2 42.1 26.8 21.0 19.8 17.1 92.6 36.6 25.8 37.2 52.2 53.9 37.0 68.2 47.1 59.2 51.8 92.3 32.8 23.9 215.2 78.1 60.2 71.4 40.5 52.1 50.4 42.1 28.6 68.6 40.6 39.5 45.2 34.3 56.7 47.4 40.0 55.9 39.6 35.4 63.0 21.0 38.3 53.3 58.1 79.6 19.9 17.3 21.4 55.7 53.0 34.5 31.0 37.5 35.7 53.6 25.4 18.3 44.5 79.5 44.2 32.8 114.1 37.2 88.5 45.5 25.2 61.8 92.7 45.8 101.1 44.1 69.6 43.8 56.9 9.6 9.2 10.4 8.8 9.3 7.5 7.2 6.5 9.7 9.1 6.3 4.2 6.3 21.0 9.4 11.0 5.9 14.9 5.2 15.2 16.0 16.6 15.8 15.5 21.1 18.8 18.0 18.5 17.5 18.1 17.1 24.7 16.0 25.7 15.3 19.9 14.5 9.4 19.7 14.2 15.9 14.1 9.4 70.1 20.0 17.5 14.7 25.0 11.9 27.3 36.4 13.7 24.8 76.3 17.8 22.9 23.2 22.1 12.2 20.4 22.9 17.7 17.0 23.4 15.6 20.8 16.1 26.7 35.6 37.4 8.4 22.7 24.2 6.1 34.6 27.1 67.6 19.9 33.9 19.6 20.6 39.4 13.1 39.1 16.1 17.6 24.6 21.1 28.2 27.2 12.0 67.2 23.2 33.9 12.8 26.3 15.0 19.0 46.0 13.2 30.0 21.5 18.6 25.6 25.5 23.8 12.2 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 299.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria No No 61000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favorable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 59.9 76.5 48.7 42.2 50.2 25.7 42.9 53.9 62.7 43.3 63.6 56.8 42.5 38.5 44.6 57.4 37.7 35.9 175.0 49.7 52.3 100.8 110.7 36.4 53.1 51.7 49.4 26.5 36.4 88.8 44.1 57.0 51.5 48.5 60.4 30.7 45.9 52.1 272.6 36.8 37.6 63.8 51.6 42.8 53.9 42.3 53.1 53.1 40.8 299.4 56.0 49.7 35.9 54.3 66.5 90.9 92.3 69.8 91.7 111.1 110.4 81.6 101.3 117.9 120.6 165.1 62.6 140.3 44.9 103.8 109.0 37.6 113.2 74.9 90.0 81.7 83.0 125.4 163.7 126.0 92.5 103.0 67.9 97.9 67.7 95.5 55.8 137.5 103.1 114.2 65.9 61.5 129.5 63.1 98.2 107.8 127.2 69.2 101.3 46.3 71.8 136.1 188.1 89.1 63.7 70.2 75.6 107.2 85.4 131.3 159.0 108.7 76.3 62.9 83.7 66.8 94.2 85.2 129.9 99.2 96.2 120.8 60.7 57.8 98.9 98.7 83.2 115.1 87.9 102.2 81.7 80.5 141.1 103.4 90.9 82.4 19.6 129.4 109.7 94.7 113.2 124.1 48.7 50.2 53.9 62.7 49.7 52.3 51.7 49.4 51.5 51.6 53.1 54.3 57.8 60.9 34.5 5.9 45.3 27.9 40.7 142.0 26.7 31.8 29.4 31.6 300.6 48.6 96.0 35.0 25.0 174.1 35.3 41.0 230.9 95.9 76.3 37.0 37.3 58.0 58.0 22.5 10.9 72.2 101.6 54.1 29.6 34.2 39.3 48.5 46.1 76.1 84.6 57.2 13.3 50.4 162.8 37.9 26.6 16.9 60.3 37.2 56.9 9.4 76.5 61.7 70.0 9.0 13.6 55.9 43.0 51.1 38.8 19.1 45.8 146.8 70.7 45.9 65.7 30.8 72.3 98.2 88.3 42.8 29.8 157.2 44.7 224.4 53.0 37.7 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537979-2603188 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199" Supported Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "CAB004272: AB_626657, HPA035199: AB_2674514" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.6 13.5 15.1 12.4 25.2 16.1 11.1 10.2 20.6 10.9 1.5 15.8 17.3 11.8 13.2 13.3 14.7 9.5 15.1 19.2 5.2 17.0 12.4 13.6 15.0 10.8 6.1 14.0 19.4 27.1 11.2 12.1 11.3 13.0 14.9 15.5 17.8 12.2 18.9 14.2 19.6 12.3 3.7 13.9 13.6 14.7 7.7 16.8 15.8 19.2 14.1 11.1 10.4 12.5 13.1 16.5 20.1 13.5 20.3 16.9 21.5 21.7 13.6 18.7 15.6 16.6 15.2 21.4 14.5 20.7 15.9 20.2 24.3 15.3 17.6 39.6 17.1 11.4 23.0 27.7 17.7 19.2 29.0 15.4 27.5 20.1 13.3 17.9 17.3 19.1 22.2 17.0 22.1 27.7 19.2 13.3 12.8 24.3 15.1 39.0 20.2 19.5 18.0 11.5 31.7 16.3 27.9 31.3 11.5 12.8 29.0 23.5 21.6 20.2 20.2 20.0 18.8 22.6 23.4 33.3 9.7 13.1 17.9 5.4 7.1 8.4 4.1 8.3 3.9 4.2 3.8 5.0 5.8 3.4 4.3 4.0 12.5 5.2 8.9 8.0 1.9 4.7 15.1 25.2 10.2 20.6 19.2 5.2 10.8 6.1 11.3 3.7 7.7 12.5 17.6 16.0 19.1 45.1 32.9 26.6 20.8 25.7 26.7 60.2 30.0 22.0 33.8 40.0 23.0 11.0 54.2 47.0 35.2 41.1 13.7 23.1 14.4 35.6 23.8 19.1 21.6 28.0 46.7 23.6 27.9 23.2 23.0 45.3 7.6 18.1 22.5 46.1 26.0 74.0 41.7 29.9 10.2 55.7 51.1 30.4 31.7 37.1 21.4 31.9 43.3 42.3 25.7 37.7 44.2 31.6 24.0 44.4 27.1 30.3 50.2 44.8 41.1 44.9 46.0 30.5 30.0 46.8 36.8 38.5 34.1 104.7 25.7 24.2 31.4 27.1 PEX1 "ZWS, ZWS1" ENSG00000127980 "Peroxisomal biogenesis factor 1" O43933 7 92487020-92528520 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis, Protein transport, Transport" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020235 Approved Supported Peroxisomes NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" Peroxisomes "HPA020235: AB_1855224" "unprognostic (4.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.55e-2)" "unprognostic (1.53e-2)" "unprognostic (4.85e-1)" "unprognostic (2.41e-2)" "unprognostic (7.81e-2)" "unprognostic (9.79e-3)" "unprognostic (2.17e-2)" "unprognostic (6.39e-2)" "unprognostic (1.68e-2)" "unprognostic (3.61e-2)" "unprognostic (2.95e-3)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (5.35e-3)" "unprognostic (4.90e-2)" 5.8 6.9 2.6 6.0 4.7 4.1 8.7 4.6 4.3 6.4 2.5 8.6 6.6 6.7 11.2 6.1 5.6 4.7 8.9 2.4 3.1 14.2 13.0 5.3 6.9 3.5 3.5 6.8 8.8 11.7 6.3 4.2 4.1 7.8 9.5 13.2 9.1 7.0 9.1 7.9 8.1 5.4 2.8 6.0 8.2 6.7 3.0 7.9 8.6 9.9 6.7 5.6 5.8 6.3 8.3 8.9 14.4 24.6 8.9 7.6 13.0 5.4 7.1 6.3 9.1 5.5 8.7 12.2 12.0 6.3 9.6 8.4 11.0 9.9 10.0 12.7 9.7 5.8 9.5 7.0 6.2 10.6 6.4 8.2 8.6 9.4 12.7 8.0 9.9 12.6 21.9 17.2 10.1 15.5 21.3 10.4 10.0 12.3 8.3 15.0 16.0 15.3 8.8 12.0 10.6 17.1 12.4 34.3 10.8 20.2 7.1 4.4 8.1 6.0 8.1 23.0 5.7 18.9 15.9 16.7 5.7 6.2 9.8 0.8 1.1 1.8 2.5 1.8 2.5 3.0 2.6 2.8 1.2 2.8 2.9 3.3 0.9 4.7 2.2 0.7 2.8 1.1 2.6 4.7 4.6 4.3 2.4 3.1 3.5 3.5 4.1 2.8 3.0 6.3 14.2 28.9 18.4 26.1 14.1 5.9 8.4 8.1 10.8 43.5 11.7 12.6 29.7 5.7 13.1 5.5 35.5 9.0 13.6 17.2 9.8 6.6 7.3 22.6 14.7 11.6 13.9 12.4 30.0 7.5 3.9 11.6 21.9 14.2 8.8 20.5 8.2 14.2 5.4 40.4 45.7 12.0 8.2 7.6 3.1 4.8 14.3 8.4 7.2 13.1 12.7 14.2 14.4 23.6 55.2 6.0 11.3 15.1 11.6 9.6 16.5 19.2 32.4 42.9 6.6 15.5 12.6 36.6 14.4 11.2 7.7 8.3 12.0 11.8 15.2 7.7 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129295 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 1126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB010065: AB_628116, HPA045385: AB_2679306, HPA073644: AB_2732231, HPA073656: AB_2732235" "prognostic unfavorable (7.05e-8)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.21e-1)" "unprognostic (8.30e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.65e-6)" "prognostic unfavorable (2.74e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (5.66e-2)" "unprognostic (2.99e-1)" "unprognostic (8.99e-3)" "unprognostic (3.58e-1)" "unprognostic (2.90e-2)" "unprognostic (6.57e-2)" 120.7 141.8 87.3 149.0 94.1 252.8 89.1 103.2 119.0 100.2 117.2 127.4 123.4 72.3 73.0 154.1 79.3 110.1 247.4 92.7 109.2 233.5 143.8 117.1 139.0 104.8 95.1 61.9 61.1 188.8 30.0 138.6 109.5 92.8 143.1 298.8 93.2 101.8 452.0 92.6 119.1 116.7 102.4 97.2 86.1 29.2 111.1 158.3 105.6 266.7 189.6 148.4 49.4 101.3 943.0 426.7 139.7 283.8 236.1 190.0 331.3 469.2 324.0 402.9 670.0 390.2 287.7 373.9 473.7 326.5 479.5 397.6 624.8 729.3 800.7 229.8 246.6 290.3 657.8 341.8 258.0 671.8 309.2 238.5 302.2 366.7 192.7 646.1 418.8 361.9 308.5 553.4 557.4 371.2 593.5 506.0 433.3 628.5 800.7 421.8 374.4 1157.0 423.8 385.4 208.0 286.6 486.3 409.0 422.9 352.6 214.8 347.9 340.2 428.1 294.3 433.4 329.0 609.5 1221.7 391.5 1207.0 750.5 286.6 170.6 360.2 321.1 121.9 382.0 135.9 128.4 144.3 132.9 333.7 101.2 130.9 140.7 281.9 140.3 527.0 130.2 168.4 606.0 87.3 94.1 103.2 119.0 92.7 109.2 104.8 95.1 109.5 102.4 111.1 101.3 166.3 150.6 168.6 20.2 174.8 144.3 272.2 1126.6 122.3 211.3 72.4 67.2 480.4 140.2 436.9 174.7 77.2 298.4 200.6 196.5 471.6 715.8 19.3 123.7 112.4 182.3 102.4 95.9 32.5 236.4 746.4 131.3 95.3 145.1 195.5 98.1 139.6 200.2 499.0 309.6 37.0 164.3 518.8 298.4 188.8 12.1 94.8 310.4 167.2 25.3 499.3 245.7 131.8 20.1 21.9 510.2 149.9 127.2 214.8 118.3 221.5 566.0 235.6 188.8 124.9 84.0 191.8 8.8 57.4 138.4 119.1 349.6 251.9 278.7 203.5 225.8 PIGS ENSG00000087111 "Phosphatidylinositol glycan anchor biosynthesis class S" Q96S52 17 28553383-28571794 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018149 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA018149: AB_1855373" "unprognostic (2.29e-2)" "unprognostic (1.37e-2)" "unprognostic (3.89e-1)" "unprognostic (2.52e-1)" "unprognostic (6.61e-2)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.65e-1)" "unprognostic (9.09e-2)" "unprognostic (2.25e-3)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (2.90e-2)" "unprognostic (1.23e-1)" "unprognostic (8.06e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (5.31e-4)" 25.0 15.5 8.3 15.5 8.5 25.3 11.4 8.2 8.6 12.9 18.6 25.5 30.9 12.0 3.3 23.5 20.1 15.6 25.4 10.5 9.1 16.6 4.9 20.2 18.9 8.8 9.4 13.3 16.8 28.5 3.3 17.4 8.8 17.7 15.7 3.4 14.8 16.2 31.4 18.5 32.2 16.1 7.8 18.2 26.9 13.4 8.7 17.5 24.3 19.7 13.7 17.7 5.3 8.0 34.7 57.4 26.5 67.9 51.1 38.2 40.1 42.3 34.5 44.4 58.1 60.4 33.8 22.3 62.9 57.8 43.1 64.5 32.4 48.2 16.6 65.8 92.5 30.1 45.3 26.2 47.8 58.5 73.8 46.7 33.6 27.8 37.8 44.5 60.3 37.8 89.3 34.1 38.5 42.6 36.9 40.2 13.2 77.9 17.6 31.2 87.8 73.6 30.6 36.9 54.3 37.7 60.3 115.4 32.8 26.4 105.4 69.5 52.2 31.5 32.5 27.1 35.0 56.5 84.0 17.0 56.6 56.8 45.1 86.2 60.4 78.9 34.3 55.0 31.0 23.5 27.5 32.5 64.9 22.3 28.8 24.0 29.4 43.0 39.6 49.8 45.2 46.3 8.3 8.5 8.2 8.6 10.5 9.1 8.8 9.4 8.8 7.8 8.7 8.0 15.7 44.8 21.4 10.7 15.9 8.3 11.3 21.1 13.6 20.5 20.5 17.1 40.7 20.0 18.8 46.0 64.6 35.0 31.6 48.5 11.7 43.5 9.5 15.3 15.7 18.7 40.7 17.9 10.9 26.3 53.4 14.9 18.3 21.5 3.8 17.1 26.4 7.9 31.1 52.2 12.6 28.3 24.4 28.1 8.0 13.1 23.9 22.9 7.2 1.9 66.1 17.5 93.7 9.0 11.7 22.5 21.6 22.6 16.8 15.0 49.0 19.1 14.4 56.1 6.6 12.3 15.9 74.2 62.0 19.3 12.5 36.4 21.8 25.0 27.6 12.4 PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted intracellular proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 244.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 247.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008214: AB_1078363, HPA011144: AB_1078364" "prognostic favorable (5.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.96e-2)" "unprognostic (9.67e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.45e-3)" "unprognostic (2.19e-2)" "unprognostic (1.84e-1)" "prognostic favorable (5.09e-5)" "unprognostic (1.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" 18.9 17.9 9.6 20.2 10.5 13.6 25.4 10.3 13.8 18.1 15.3 41.2 44.1 12.3 27.7 20.3 19.8 15.6 33.6 9.5 10.1 33.4 21.6 14.6 23.9 10.3 9.8 10.0 12.5 19.9 10.4 15.0 10.7 17.4 46.8 15.8 16.7 13.5 58.6 16.4 36.3 17.3 10.6 14.5 20.0 4.8 9.8 35.3 24.8 37.1 22.7 17.6 12.8 11.1 54.8 15.4 31.8 23.0 20.0 27.7 0.1 26.2 29.0 22.1 25.5 0.2 24.2 12.4 13.7 19.8 32.7 12.6 21.9 72.0 46.1 247.5 14.0 97.6 12.5 17.4 43.3 29.8 22.4 30.6 25.8 20.6 42.0 18.9 32.2 41.0 5.5 86.2 54.3 12.0 32.1 33.6 20.6 44.5 8.9 20.1 15.6 39.6 50.6 11.4 25.1 32.7 26.0 40.6 50.6 22.5 32.8 41.4 23.1 28.0 34.8 24.7 51.7 16.4 25.3 25.6 48.6 18.6 16.1 244.3 18.8 38.3 43.0 25.5 54.0 48.9 53.7 56.7 27.6 42.9 51.1 51.2 22.8 52.7 17.9 44.3 74.9 44.0 9.6 10.5 10.3 13.8 9.5 10.1 10.3 9.8 10.7 10.6 9.8 11.1 27.8 12.8 25.5 25.5 22.0 26.4 23.4 144.2 27.3 11.8 56.9 58.7 58.7 22.8 49.7 22.0 0.0 88.6 23.1 139.2 109.5 82.5 0.8 39.6 28.1 21.2 26.5 25.2 18.8 51.1 108.7 25.3 20.9 22.0 90.7 14.6 15.0 27.5 82.8 10.1 26.7 124.2 83.4 21.7 35.6 1.9 16.4 33.0 33.8 21.5 84.3 24.4 24.7 20.1 40.5 82.7 157.2 19.9 23.0 27.3 191.3 76.8 52.6 15.1 0.0 26.0 33.2 21.2 13.7 41.1 30.3 65.8 33.0 23.1 106.1 24.0 PLPBP PROSC ENSG00000147471 "Pyridoxal phosphate binding protein" O94903 8 37762595-37779768 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 101.8;Exocrine glandular cells: 49.8;Hofbauer cells: 47.3;Proximal tubular cells: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017033, HPA023646, HPA023733" Approved Enhanced Cytosol NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB017033: , HPA023646: AB_1855741, HPA023733: AB_1855742" "unprognostic (1.55e-2)" "unprognostic (2.17e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-2)" "unprognostic (2.36e-1)" "unprognostic (7.78e-3)" "unprognostic (1.80e-1)" "unprognostic (4.28e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (9.41e-3)" "unprognostic (3.16e-2)" "unprognostic (3.99e-2)" "unprognostic (2.90e-1)" "unprognostic (7.85e-2)" 34.2 23.1 22.2 21.2 24.3 14.6 23.3 25.3 27.1 22.1 26.8 47.2 34.5 19.2 23.3 20.2 27.5 19.1 39.2 24.0 25.0 58.5 78.2 25.7 25.0 22.8 24.9 24.7 40.3 37.4 16.2 20.1 23.7 20.2 37.9 10.9 28.3 27.8 46.4 17.0 37.3 25.9 23.7 25.0 33.5 8.4 24.5 27.4 31.8 42.1 29.0 22.9 16.1 28.6 50.3 45.4 35.1 32.0 25.9 31.1 31.6 55.2 45.8 34.7 38.9 51.6 24.3 58.4 61.9 39.9 55.5 41.4 65.4 52.5 56.6 49.9 34.3 79.4 16.4 51.7 51.6 36.8 52.5 22.9 49.8 33.0 52.0 37.6 52.3 78.3 42.8 42.1 28.7 34.8 116.4 32.4 43.0 92.8 41.9 73.6 46.6 34.8 56.5 60.0 21.5 25.1 45.4 20.0 56.8 25.4 44.2 48.6 52.1 19.1 60.7 69.8 38.1 43.3 90.9 43.0 27.4 51.8 35.0 164.3 109.6 136.1 85.6 130.0 90.0 77.8 87.8 83.6 115.2 61.9 77.0 74.3 46.9 75.9 147.4 66.5 116.7 110.2 22.2 24.3 25.3 27.1 24.0 25.0 22.8 24.9 23.7 23.7 24.5 28.6 35.9 9.6 26.5 0.0 6.7 0.0 0.0 0.0 0.0 0.0 27.8 23.0 0.0 0.0 8.1 31.3 0.0 21.2 20.0 0.0 101.8 38.2 0.0 12.8 20.7 13.5 0.0 0.0 0.0 49.8 31.6 13.9 0.0 19.6 12.6 14.8 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 11.9 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.8 0.0 0.0 82.2 13.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 12.9 9.8 17.1 0.0 0.0 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Proximal tubular cells: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 20.8 27.6 11.9 9.7 12.6 8.7 22.6 12.0 11.8 13.9 16.9 15.4 18.9 14.0 18.1 21.0 24.7 9.4 42.1 11.1 14.2 41.2 40.1 9.8 10.8 12.1 13.5 22.4 28.8 25.2 13.5 8.0 12.4 12.8 12.3 16.8 26.9 10.8 77.9 15.0 11.4 12.1 12.5 9.4 19.5 7.8 15.6 16.3 29.9 66.0 10.2 8.9 13.3 11.9 44.7 18.1 2.8 44.4 0.9 0.5 11.9 13.7 1.5 23.0 14.1 18.1 16.1 13.9 0.1 4.5 0.3 25.7 0.0 45.6 39.2 0.4 32.0 10.0 32.8 38.6 28.6 17.8 14.1 29.5 45.7 11.7 27.3 5.5 16.2 0.3 39.9 0.5 0.3 11.8 0.3 17.2 46.9 30.7 38.0 0.3 0.2 15.6 30.6 20.3 25.3 12.7 41.2 16.8 23.7 49.7 26.1 13.0 9.4 0.2 11.4 35.5 0.2 20.3 0.3 27.0 0.2 0.1 3.7 7.4 11.4 9.7 6.1 13.5 7.0 14.7 8.7 6.7 22.2 16.7 11.3 10.8 0.7 11.9 12.5 16.3 6.0 9.3 11.9 12.6 12.0 11.8 11.1 14.2 12.1 13.5 12.4 12.5 15.6 11.9 10.7 9.6 12.5 3.3 8.2 11.9 16.7 46.0 17.6 11.3 38.2 33.5 55.0 20.0 24.3 20.2 0.0 28.7 7.8 31.2 95.9 34.2 3.1 35.9 20.6 10.6 19.8 15.6 2.8 48.7 21.3 14.6 13.7 15.5 8.2 17.3 13.2 62.1 28.7 10.1 3.6 30.6 38.7 9.2 10.2 3.7 16.4 12.1 17.8 1.0 13.3 36.1 6.2 2.5 1.0 39.8 25.1 20.3 14.2 15.3 47.6 126.4 31.0 15.0 6.6 6.6 14.6 22.2 21.4 24.0 16.8 14.0 6.4 49.0 32.3 16.0 PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.6" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1098.2;Inhibitory neurons: 1704.4;Oligodendrocyte precursor cells: 890.2" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "A-431: 88.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063136 Supported Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA063136: AB_2684948" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.85e-3)" "unprognostic (2.28e-6)" "unprognostic (5.00e-2)" "unprognostic (1.15e-1)" "prognostic favorable (3.35e-6)" "unprognostic (3.04e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.58e-2)" "prognostic favorable (1.49e-14)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.07e-3)" 2.3 2.9 4.2 0.6 3.2 0.0 1.6 7.6 13.0 3.3 33.9 7.4 7.6 0.9 1.5 3.3 1.5 2.6 36.3 3.1 10.7 29.0 44.6 3.1 0.2 4.1 4.1 1.2 3.8 38.5 4.8 0.1 2.6 3.3 9.1 4.2 29.3 3.0 29.5 8.2 6.6 1.9 2.4 0.8 4.3 4.5 7.2 2.3 17.7 37.2 0.4 1.1 1.0 4.1 88.6 0.0 1.6 0.0 2.6 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 4.5 10.7 0.0 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.7 0.0 12.3 0.1 4.0 0.2 2.8 0.0 3.5 4.2 0.5 1.4 0.0 0.7 0.7 0.0 1.6 8.1 0.1 0.1 1.6 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.2 7.6 13.0 3.1 10.7 4.1 4.1 2.6 2.4 7.2 4.1 2.5 19.2 2.6 240.6 0.9 0.9 4.1 7.4 1.2 7.0 2.7 1.5 90.9 47.1 6.3 36.8 39.6 0.0 0.0 36.0 52.8 12.0 78.3 7.2 1.3 0.8 26.7 0.0 1098.2 0.0 0.0 2.4 4.1 9.7 1.3 0.2 1.1 88.8 0.0 0.0 1704.4 17.0 38.7 2.5 0.3 69.7 0.9 0.6 7.2 24.4 0.1 6.4 0.0 890.2 28.8 0.6 7.3 2.2 1.8 1.4 32.0 26.8 4.8 1.9 0.0 37.1 5.1 0.8 0.6 2.6 1.1 0.0 1.0 1.9 21.9 1.5 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666000-21700015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 190.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA035344: AB_10672863, HPA055637: AB_2682869" "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 8.9 14.2 4.7 12.8 5.7 6.3 9.5 4.0 7.0 11.6 2.1 12.1 8.1 12.0 9.3 16.4 10.7 9.5 13.9 5.8 4.8 12.6 15.0 10.1 16.4 3.5 2.9 10.7 19.2 16.4 14.3 9.1 3.9 12.4 10.6 9.0 14.7 9.5 18.8 12.3 13.3 9.9 3.6 14.0 13.9 10.1 3.1 15.8 18.8 13.0 16.4 11.7 12.1 4.8 20.4 17.1 18.1 20.1 19.2 17.6 15.8 19.3 17.9 28.0 24.5 21.3 10.3 34.0 12.7 27.2 13.9 22.9 28.6 23.6 16.2 19.2 28.2 26.7 14.2 32.4 14.7 42.5 21.5 17.4 21.2 19.4 14.0 15.1 25.1 18.5 190.3 17.9 19.6 28.6 20.5 13.7 20.2 35.7 14.9 23.7 31.1 5.7 14.2 14.1 30.8 18.4 21.2 32.7 9.7 11.3 27.1 20.3 27.5 15.8 25.1 17.5 12.7 19.2 17.5 24.7 21.6 22.6 24.9 1.5 9.7 5.1 9.6 15.3 12.2 7.2 11.5 12.6 13.7 8.3 10.5 9.4 2.3 14.1 22.6 11.9 15.6 12.1 4.7 5.7 4.0 7.0 5.8 4.8 3.5 2.9 3.9 3.6 3.1 4.8 9.8 9.6 29.5 15.0 21.5 3.2 7.9 10.9 10.8 26.3 13.4 10.2 5.7 27.1 16.6 14.7 33.3 15.8 39.4 23.9 13.7 12.8 66.8 15.4 14.8 8.0 11.4 17.7 19.9 16.7 13.3 10.3 39.3 19.5 17.1 16.6 10.4 18.9 15.3 18.5 24.2 20.6 14.2 21.0 5.3 90.9 12.2 15.5 1.8 8.4 16.6 11.5 52.5 12.5 17.4 18.5 17.4 13.5 23.8 10.9 14.2 9.1 11.9 31.4 0.0 11.2 9.4 23.6 17.3 12.3 5.7 22.2 24.5 14.8 20.8 12.6 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "HPA050940: AB_2681283" "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 32.8 25.2 20.9 24.4 22.6 42.2 29.9 22.1 27.0 22.8 18.1 28.4 20.4 19.7 23.7 25.0 18.5 18.6 21.6 21.7 22.0 32.6 25.1 24.0 30.8 21.1 20.4 19.6 27.7 32.6 14.7 19.5 21.6 20.2 30.9 17.5 26.1 19.7 69.9 23.5 22.5 21.8 21.8 27.6 20.9 28.1 20.7 38.9 31.5 53.5 36.2 22.9 18.7 26.9 32.6 23.4 41.6 39.3 43.6 36.2 41.8 33.7 36.5 48.7 40.4 37.6 33.5 46.5 25.5 45.6 41.3 64.7 56.8 36.7 56.2 42.0 27.3 38.3 33.5 33.6 35.7 67.6 50.8 30.0 49.2 40.1 38.1 37.5 46.2 52.6 45.7 52.2 53.3 48.6 64.0 42.5 38.8 90.4 42.8 51.5 62.7 62.2 42.1 32.3 42.8 42.3 60.3 47.8 41.0 35.0 74.0 42.0 45.3 29.7 28.4 58.4 45.5 57.5 112.4 62.3 40.1 43.5 49.4 61.7 21.8 35.9 22.4 28.6 27.2 26.8 28.2 25.3 24.0 20.2 27.6 26.5 50.9 23.7 33.6 17.2 38.9 25.8 20.9 22.6 22.1 27.0 21.7 22.0 21.1 20.4 21.6 21.8 20.7 26.9 39.8 41.7 37.8 20.5 62.6 77.4 55.5 64.0 60.3 14.0 42.5 28.3 37.9 31.5 43.1 27.6 8.4 45.7 43.7 47.5 56.7 46.3 130.5 22.7 21.5 44.8 47.9 60.2 35.3 55.2 57.5 37.2 34.1 24.7 45.0 20.4 48.5 41.7 52.3 15.2 30.0 43.0 67.1 61.2 60.9 83.3 29.8 51.8 44.4 32.8 60.0 29.2 40.2 22.6 35.8 48.2 37.4 36.1 82.7 47.2 43.7 79.1 34.3 12.5 52.6 28.7 46.1 124.8 48.3 76.8 87.5 87.2 57.1 23.2 43.9 59.8 PPTC7 TA-PP2C ENSG00000196850 "Protein phosphatase targeting COQ7" Q8NI37 12 110533245-110583318 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.43e-5)" "prognostic unfavorable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favorable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 18.8 25.5 6.9 16.1 7.3 52.3 13.4 12.1 11.1 15.5 8.3 15.7 13.4 14.3 6.4 21.6 11.3 15.0 40.0 6.5 14.1 21.5 21.0 15.6 20.7 12.7 12.4 13.1 13.2 30.6 8.4 10.7 12.1 12.3 16.7 15.6 17.8 13.4 88.7 21.5 13.2 16.1 9.2 15.2 11.9 14.0 13.0 18.4 11.6 140.0 18.4 19.0 19.1 7.4 24.3 13.6 11.4 12.0 27.8 24.3 16.3 10.9 14.3 11.7 11.7 15.4 9.3 42.2 11.1 10.8 16.7 23.0 23.1 25.3 23.5 30.9 19.1 37.5 14.4 16.7 26.3 41.8 29.6 21.0 40.7 16.6 48.4 17.4 22.5 28.8 28.3 11.7 19.2 6.3 37.2 35.7 16.1 13.0 25.0 30.7 15.3 25.8 48.7 26.7 18.4 14.2 20.6 28.2 24.4 11.0 13.4 22.1 25.9 10.7 11.5 32.8 18.6 33.5 40.0 46.7 18.0 22.6 21.4 0.0 0.6 0.5 0.8 0.5 0.8 0.4 0.6 0.6 0.4 0.7 0.7 0.6 2.1 0.6 0.4 0.5 0.5 0.2 6.9 7.3 12.1 11.1 6.5 14.1 12.7 12.4 12.1 9.2 13.0 7.4 14.1 22.4 28.3 16.0 35.7 91.9 53.1 33.9 56.9 8.6 20.2 12.8 105.4 12.8 36.0 9.2 14.6 7.5 28.2 36.7 17.6 7.7 29.7 34.4 20.4 22.3 16.8 7.8 15.5 8.2 8.4 26.1 12.8 63.3 23.5 8.6 15.4 29.5 17.4 13.5 19.8 15.2 30.5 28.3 97.6 33.2 11.5 30.8 33.8 21.5 31.9 4.8 20.6 19.1 11.7 14.6 15.1 9.8 28.2 57.3 16.5 13.1 35.4 23.8 13.1 22.8 22.4 15.9 24.1 57.1 104.3 6.7 28.7 8.2 17.2 77.5 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1060.4;Proximal tubular cells: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, CAB079909" Enhanced Supported Mitochondria NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 165.7 335.3 92.4 96.0 92.6 82.3 138.3 101.3 116.0 103.4 139.2 133.3 137.8 87.0 120.8 83.3 116.7 88.0 278.2 95.2 104.5 385.7 571.2 74.9 108.4 97.2 97.1 74.9 96.2 223.8 60.0 126.3 99.0 126.7 139.8 52.5 132.1 131.7 376.0 38.0 132.1 130.0 100.4 76.3 97.5 48.3 98.6 98.3 176.7 402.7 104.0 112.8 65.1 102.7 350.6 392.2 234.1 267.3 241.7 259.8 145.9 244.8 414.8 364.5 380.7 303.4 339.9 407.2 208.8 290.8 173.4 155.5 391.5 296.1 408.8 401.5 411.4 183.7 149.7 542.4 252.5 347.8 212.7 306.8 186.4 292.1 269.7 261.2 268.6 245.2 230.0 82.5 338.7 140.2 265.1 292.7 218.9 264.0 229.3 276.5 339.7 281.5 623.8 164.6 103.0 149.2 259.8 346.1 332.2 201.0 179.6 411.5 190.5 118.3 178.1 170.9 323.1 128.0 200.7 327.0 185.7 507.4 107.3 144.4 429.1 246.9 110.5 369.5 142.7 179.9 145.6 134.6 382.1 149.8 149.5 134.0 239.9 132.8 333.9 214.8 205.7 510.2 92.4 92.6 101.3 116.0 95.2 104.5 97.2 97.1 99.0 100.4 98.6 102.7 61.4 48.1 74.5 14.4 65.1 69.8 117.8 274.0 81.4 27.5 145.2 105.2 236.5 131.5 119.0 147.1 10.4 328.4 50.6 84.5 1060.4 124.5 5.0 105.1 76.0 78.3 110.9 132.8 15.4 75.1 212.0 100.8 116.7 77.3 52.6 131.0 73.2 390.0 247.6 40.4 15.4 132.5 221.8 164.2 96.0 10.5 77.3 127.9 133.4 10.3 158.4 76.9 39.1 12.5 18.8 63.8 99.3 101.2 153.7 95.1 176.1 937.8 163.4 24.8 72.3 63.1 105.3 11.2 23.2 146.4 52.6 155.0 56.1 440.0 207.0 119.6 PRKAB2 ENSG00000131791 "Protein kinase AMP-activated non-catalytic subunit beta 2" O43741 1 147155106-147172550 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.2;tongue: 103.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044342 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "HPA044342: AB_10966508" "prognostic unfavorable (4.55e-4)" "unprognostic (2.03e-2)" "unprognostic (1.84e-1)" "unprognostic (4.03e-2)" "unprognostic (9.59e-3)" "prognostic unfavorable (7.32e-4)" "unprognostic (6.30e-2)" "unprognostic (1.23e-1)" "unprognostic (3.06e-2)" "unprognostic (6.78e-2)" "unprognostic (4.65e-2)" "unprognostic (1.98e-1)" "unprognostic (5.34e-2)" "unprognostic (1.31e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (6.78e-7)" "unprognostic (4.78e-2)" 12.4 10.8 9.4 7.8 10.1 9.0 11.8 12.5 13.1 14.8 6.0 23.4 32.0 18.7 8.5 10.3 12.9 7.1 25.8 10.1 9.5 9.5 56.3 10.0 6.5 10.8 10.1 11.7 34.8 64.7 6.7 12.3 11.0 12.7 10.7 14.7 8.2 19.4 97.2 15.4 20.8 19.8 10.8 8.5 18.1 6.7 10.6 5.9 6.3 103.8 5.6 18.6 14.0 11.2 7.8 4.2 11.1 8.6 25.7 22.1 39.7 14.3 7.9 9.5 10.3 17.1 15.1 13.9 7.1 11.6 5.5 20.2 13.1 16.1 9.2 5.5 9.0 6.2 15.2 27.8 17.7 7.4 2.6 17.4 31.7 9.9 46.0 14.1 9.4 10.6 8.9 5.6 8.2 7.8 5.5 4.1 23.3 13.4 18.4 8.5 14.8 6.9 6.8 6.1 7.1 13.2 10.8 12.1 52.8 39.6 11.4 9.1 10.8 10.6 23.3 9.9 23.6 8.9 10.1 7.1 11.0 6.4 14.1 0.9 0.3 0.6 0.4 0.4 0.7 0.3 0.4 0.3 0.5 0.3 0.5 0.3 0.1 1.5 0.5 0.2 0.2 0.2 9.4 10.1 12.5 13.1 10.1 9.5 10.8 10.1 11.0 10.8 10.6 11.2 10.4 3.2 2.0 14.0 10.6 16.6 11.8 11.4 18.2 14.5 6.7 8.1 66.2 20.0 5.3 18.4 14.6 21.9 10.3 22.7 1.9 6.1 0.8 5.4 15.1 8.2 11.4 3.4 23.2 7.0 42.1 13.6 13.7 10.4 1.3 11.8 6.8 44.9 5.7 11.8 18.8 12.6 10.2 8.9 12.5 1.8 9.6 7.3 16.0 10.3 12.2 6.4 11.3 25.1 21.3 9.9 12.0 16.1 9.0 7.2 55.1 5.4 7.0 19.5 19.7 11.3 20.4 13.9 11.2 13.1 14.1 20.5 9.7 43.4 10.1 4.8 PRKAG1 ENSG00000181929 "Protein kinase AMP-activated non-catalytic subunit gamma 1" P54619 12 49002274-49018807 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 339.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077805 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA077805: AB_2686855" "unprognostic (3.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.45e-1)" "unprognostic (4.68e-2)" "unprognostic (1.93e-2)" "unprognostic (5.35e-2)" "unprognostic (8.49e-2)" "prognostic favorable (1.83e-4)" "unprognostic (3.40e-1)" "unprognostic (2.57e-1)" "unprognostic (1.97e-2)" "unprognostic (5.57e-2)" 42.8 54.5 36.4 29.8 40.5 47.4 50.5 39.9 46.3 37.6 41.9 40.7 32.6 32.9 59.1 44.2 33.4 31.3 80.9 38.2 38.6 50.5 49.4 30.8 38.7 34.5 35.5 25.6 37.4 59.1 33.9 35.1 36.5 37.7 47.8 42.3 36.1 39.9 122.7 43.0 29.9 44.8 33.5 28.6 33.5 33.5 34.9 41.8 37.7 112.4 50.8 40.1 30.8 41.5 79.8 45.8 50.5 76.3 157.8 141.6 33.2 85.5 117.4 84.4 55.7 50.9 66.1 50.4 72.9 98.9 53.9 65.4 42.5 115.6 80.4 69.6 57.1 70.4 66.5 34.2 120.2 97.7 54.6 110.0 94.6 65.9 141.4 123.6 90.3 67.6 60.1 70.0 108.6 52.8 45.8 31.5 29.1 339.6 96.8 24.1 53.3 59.7 114.0 67.6 42.1 57.7 61.0 99.1 142.5 39.7 134.1 49.5 72.5 44.4 52.3 87.7 63.5 109.1 113.3 36.0 89.3 69.9 34.5 87.3 59.8 59.9 53.0 58.7 50.0 51.9 46.1 47.6 68.7 51.3 41.3 43.0 70.9 71.8 56.0 45.2 66.8 73.0 36.4 40.5 39.9 46.3 38.2 38.6 34.5 35.5 36.5 33.5 34.9 41.5 20.2 9.6 22.7 16.6 31.2 20.0 30.3 64.5 11.4 29.2 24.3 20.8 49.8 18.6 29.9 36.8 37.5 65.6 30.5 24.5 76.3 48.3 11.3 11.4 21.3 21.9 21.0 30.3 18.1 46.4 57.7 26.7 15.8 12.9 21.5 31.4 30.4 23.2 52.2 15.2 24.1 31.6 63.1 36.2 26.5 15.7 36.7 26.7 37.4 9.4 55.5 41.6 55.6 23.1 21.1 47.8 16.5 27.1 25.0 24.2 38.6 69.3 19.2 30.1 19.7 18.5 27.5 49.3 43.9 19.1 26.0 67.0 26.3 33.6 32.2 23.6 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PRMT3 HRMT1L3 ENSG00000185238 "Protein arginine methyltransferase 3" O60678 11 20387558-20509338 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Excitatory neurons: 55.5;Inhibitory neurons: 66.9;Oligodendrocytes: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007832, CAB022083" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022083: , HPA007832: AB_1855721" "unprognostic (2.08e-2)" "unprognostic (4.43e-2)" "unprognostic (1.08e-2)" "unprognostic (5.98e-2)" "unprognostic (2.57e-2)" "unprognostic (8.97e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (2.01e-1)" "unprognostic (9.92e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (9.15e-2)" "unprognostic (7.22e-2)" "unprognostic (8.86e-2)" "unprognostic (2.09e-1)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" 5.0 7.4 4.5 8.1 5.4 8.6 9.6 5.0 8.3 5.1 3.7 6.5 7.6 7.7 3.8 8.2 8.5 5.4 9.7 5.2 5.3 6.9 5.4 4.7 7.8 5.4 5.0 8.1 6.7 11.1 2.6 6.9 5.5 6.1 7.7 7.7 6.5 5.7 10.2 6.2 5.9 7.3 5.0 5.5 6.6 4.3 4.8 9.9 19.8 7.7 8.8 8.0 4.6 7.9 26.5 31.4 18.9 17.4 11.8 19.5 36.1 17.9 15.5 24.5 18.5 25.9 7.2 55.8 12.8 14.1 22.4 34.0 27.2 25.6 37.7 26.1 26.4 26.9 25.5 23.3 24.0 48.8 11.4 16.3 26.3 16.1 54.6 10.3 19.7 19.8 61.1 15.3 15.6 26.7 38.6 16.6 26.7 45.1 27.8 27.9 42.3 46.3 23.8 20.2 18.9 24.8 31.0 28.5 23.2 20.3 30.1 14.1 13.3 19.8 17.3 32.7 34.2 9.1 9.7 58.3 15.7 34.1 39.0 3.8 5.1 4.4 4.4 6.1 7.7 5.3 5.5 4.9 9.8 4.9 6.0 5.2 1.3 10.7 5.2 2.0 3.6 3.9 4.5 5.4 5.0 8.3 5.2 5.3 5.4 5.0 5.5 5.0 4.8 7.9 5.5 9.6 5.1 54.2 11.8 6.0 7.7 6.7 15.9 3.8 6.5 4.2 11.8 4.3 5.7 0.0 2.1 11.4 5.0 3.2 9.8 6.9 3.1 6.0 8.2 5.5 7.8 29.2 55.5 5.1 11.0 8.9 11.2 5.5 5.7 8.0 2.9 4.3 6.5 6.7 66.9 7.3 14.2 5.3 3.6 1.0 6.5 10.9 3.6 35.6 6.7 5.6 2.1 41.7 63.2 5.1 2.2 6.4 8.9 9.5 3.5 5.9 5.8 6.6 0.0 7.8 6.7 13.7 9.6 18.7 5.8 7.3 7.0 12.5 7.6 5.7 PRPF4 "HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60" ENSG00000136875 "Pre-mRNA processing factor 4" O43172 9 113275642-113294009 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021794, HPA022248" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA021794: AB_1855772, HPA022248: AB_1855773" "unprognostic (1.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (9.35e-4)" "unprognostic (1.95e-2)" "unprognostic (6.57e-2)" "unprognostic (3.14e-2)" "unprognostic (5.00e-2)" "unprognostic (6.76e-3)" "unprognostic (2.18e-3)" "unprognostic (4.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" 11.6 14.7 9.2 15.2 9.5 15.1 13.4 10.3 10.9 11.2 8.6 11.1 9.9 13.5 19.4 14.9 12.3 10.3 11.0 9.4 9.5 15.4 16.2 9.4 15.6 8.9 8.9 14.8 14.4 25.4 12.2 12.5 9.2 13.3 12.3 13.1 11.2 11.1 18.1 14.6 9.8 13.2 9.0 11.6 10.3 11.6 9.1 16.9 10.2 15.2 17.6 16.7 11.3 9.6 36.6 61.3 40.3 44.4 27.8 28.6 40.4 56.1 28.1 60.2 44.2 60.4 33.4 76.5 32.5 30.3 62.2 81.8 84.9 48.8 66.2 54.2 32.1 39.1 50.4 43.7 25.2 68.0 34.2 20.7 32.7 63.1 59.9 22.6 28.9 41.8 67.5 40.9 51.2 57.3 65.1 47.9 63.9 94.2 66.5 59.4 95.9 51.4 26.0 28.9 52.7 35.5 82.9 44.0 26.0 32.0 68.3 35.0 29.8 49.1 37.3 63.0 72.4 52.1 153.1 73.3 37.6 42.9 63.8 27.4 16.2 16.1 14.7 19.4 17.1 17.1 14.4 13.3 20.4 17.4 14.5 14.6 5.2 18.4 24.6 13.4 14.6 14.8 9.2 9.5 10.3 10.9 9.4 9.5 8.9 8.9 9.2 9.0 9.1 9.6 15.7 9.6 18.4 6.8 23.7 15.7 17.6 10.4 18.8 22.9 12.7 14.6 12.9 12.8 15.2 18.4 18.8 27.7 26.6 5.8 25.4 18.6 17.2 17.5 24.7 12.6 17.5 20.0 8.6 16.9 34.5 16.4 10.2 21.9 19.0 21.5 6.4 9.9 18.4 28.6 8.3 13.0 10.2 13.5 17.8 13.0 11.5 20.5 5.4 2.8 27.3 22.7 18.6 4.0 5.7 15.5 9.6 10.9 15.7 20.6 8.1 16.9 14.3 24.1 0.0 16.9 17.5 28.6 21.0 21.4 18.8 21.5 20.0 24.7 14.0 16.9 PSMA1 "HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30" ENSG00000129084 "Proteasome 20S subunit alpha 1" P25786 11 14504874-14643635 "Enzymes, Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033765, HPA037646, HPA043891, CAB079995" Supported Supported "Nucleoplasm,Nuclear bodies,Centrosome" NA NA 20000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Nuclear bodies, Centrosome" "CAB033765: AB_2253026, CAB079995: , HPA037646: AB_10670386, HPA043891: AB_2678718" "unprognostic (1.72e-2)" "unprognostic (4.97e-2)" "unprognostic (7.33e-2)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (6.66e-3)" "prognostic unfavorable (3.79e-5)" "unprognostic (3.28e-3)" "unprognostic (7.44e-2)" "unprognostic (3.43e-3)" "unprognostic (8.27e-3)" "unprognostic (8.77e-2)" "prognostic unfavorable (4.03e-11)" "unprognostic (1.93e-1)" "unprognostic (1.69e-1)" "unprognostic (4.66e-2)" "unprognostic (1.23e-2)" 87.2 85.5 55.1 94.9 57.8 135.8 96.2 55.4 68.2 76.8 58.7 92.5 96.4 80.7 108.0 94.7 79.4 79.6 140.5 59.4 64.4 98.4 139.2 77.5 114.9 55.8 56.6 79.4 54.6 78.5 50.4 113.0 58.8 81.7 101.9 63.2 74.4 85.8 168.7 80.5 86.1 96.1 56.6 75.6 75.7 56.2 60.2 122.2 88.4 152.6 109.9 111.2 56.0 58.6 408.8 279.8 227.8 275.7 223.7 225.5 193.3 232.9 305.2 348.3 283.9 244.2 500.1 349.5 262.1 248.6 315.4 303.1 259.3 290.1 328.3 344.0 389.6 220.4 190.5 326.1 291.0 355.3 277.5 217.8 171.6 188.9 390.7 252.7 347.0 271.6 398.9 283.4 315.2 277.8 334.0 319.5 191.6 340.5 414.1 223.3 336.1 217.5 313.0 304.7 188.2 119.3 246.6 273.9 229.0 233.8 164.4 222.9 272.0 226.2 222.9 402.7 295.4 123.3 366.1 319.9 334.8 291.1 296.6 115.5 191.2 47.5 97.7 139.8 128.0 104.1 110.8 109.7 243.3 95.3 98.5 94.4 36.3 145.1 137.5 138.7 154.9 235.8 55.1 57.8 55.4 68.2 59.4 64.4 55.8 56.6 58.8 56.6 60.2 58.6 119.0 83.3 90.2 64.3 101.7 142.9 231.2 365.7 76.2 50.3 105.7 125.9 0.0 82.9 176.1 88.3 18.8 469.5 135.3 49.2 256.3 228.5 75.5 84.0 94.0 135.5 40.1 163.9 56.8 233.1 370.6 128.5 66.8 79.8 78.2 134.7 95.3 127.9 292.9 57.2 66.3 63.6 231.9 161.8 170.5 36.3 116.5 153.6 144.1 122.7 263.7 111.6 168.9 64.8 35.3 223.2 88.6 127.5 112.1 209.1 135.0 257.1 115.1 54.8 85.5 99.2 129.8 174.9 80.1 114.3 151.9 627.3 130.7 137.2 97.1 248.1 PSMA3 HC8 ENSG00000100567 "Proteasome 20S subunit alpha 3" P25788 14 58244843-58272012 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000905 Approved NA NA 9700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "HPA000905: AB_1079702" "unprognostic (3.60e-1)" "unprognostic (4.81e-3)" "unprognostic (1.17e-1)" "unprognostic (2.19e-2)" "unprognostic (4.91e-1)" "unprognostic (5.79e-2)" "unprognostic (1.97e-3)" "unprognostic (1.27e-1)" "unprognostic (7.92e-2)" "unprognostic (7.36e-3)" "unprognostic (1.65e-2)" "unprognostic (7.57e-2)" "unprognostic (1.83e-3)" "unprognostic (2.33e-2)" "unprognostic (6.47e-2)" "prognostic favorable (2.91e-4)" "unprognostic (2.16e-1)" 74.1 88.6 50.0 84.8 52.6 82.8 82.1 54.9 61.8 59.6 54.2 76.7 81.3 55.4 127.6 75.8 57.9 60.7 99.9 51.2 55.2 94.3 162.2 69.0 104.1 53.2 52.3 40.4 55.4 72.9 46.6 90.8 53.3 60.9 82.9 48.3 54.7 76.3 170.6 53.1 74.3 78.6 55.8 66.6 61.0 41.3 51.9 108.6 74.9 130.4 96.9 102.5 48.6 56.6 359.2 214.3 215.1 179.2 166.4 154.3 277.8 187.2 209.3 257.4 256.8 317.8 294.2 304.1 330.9 171.3 202.4 243.9 249.2 200.9 299.7 262.3 148.9 208.5 150.9 360.8 314.2 340.4 170.0 132.8 142.2 179.2 169.1 151.7 307.2 242.0 201.3 174.6 209.3 400.4 299.7 314.4 144.9 286.8 328.3 249.3 279.6 222.7 377.5 339.7 202.9 100.3 167.5 261.8 189.5 201.6 273.3 244.9 198.3 148.4 287.1 167.6 249.4 68.4 137.3 314.1 215.7 260.2 184.1 95.3 78.9 52.0 71.2 98.9 92.2 85.8 87.1 86.0 91.8 61.9 69.5 80.8 48.2 94.1 85.6 122.4 112.6 95.5 50.0 52.6 54.9 61.8 51.2 55.2 53.2 52.3 53.3 55.8 51.9 56.6 132.9 118.6 119.2 21.9 93.7 118.7 169.6 418.7 71.2 43.5 69.2 77.6 117.0 71.4 195.7 88.3 35.5 387.5 104.5 83.3 166.3 241.3 24.7 127.6 95.6 137.7 64.4 60.6 27.6 231.1 269.2 108.5 59.1 109.1 95.7 412.6 66.4 145.4 184.0 42.1 29.1 103.8 250.3 59.2 77.5 27.4 109.3 89.4 108.5 26.2 206.0 87.3 84.5 32.6 33.6 192.9 89.0 106.1 118.4 167.5 108.9 297.5 157.4 68.6 98.6 83.7 279.6 109.3 66.9 89.8 106.0 403.5 99.3 104.9 108.4 171.6 PSMC2 "MSS1, Nbla10058, S7" ENSG00000161057 "Proteasome 26S subunit, ATPase 2" P35998 7 103328570-103370346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019238, HPA049621" Supported Supported "Cytosol,Cytoplasmic bodies" NA NA 190000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA019238: AB_1855834, HPA049621: AB_2680833" "unprognostic (4.00e-2)" "unprognostic (6.66e-2)" "unprognostic (2.55e-1)" "unprognostic (3.58e-1)" "unprognostic (1.57e-3)" "unprognostic (3.55e-2)" "unprognostic (2.08e-2)" "unprognostic (6.08e-2)" "unprognostic (7.73e-2)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" "unprognostic (4.71e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (9.76e-2)" "unprognostic (1.41e-1)" 34.1 33.6 19.6 31.7 21.6 32.0 25.6 23.7 29.5 26.2 24.3 26.2 25.2 23.5 27.8 27.2 23.1 22.0 35.9 20.5 22.9 39.9 54.2 23.5 29.6 22.5 21.0 21.2 16.5 41.4 16.1 30.9 22.3 27.1 22.8 22.3 23.8 26.4 87.2 27.6 24.5 29.6 24.3 22.4 29.5 25.8 21.7 42.4 29.2 77.1 33.5 34.3 17.7 24.8 133.5 78.3 84.4 98.2 93.0 69.7 58.5 102.5 97.9 123.7 122.7 92.7 97.3 100.1 199.2 94.7 168.1 71.0 109.2 76.6 128.7 153.3 68.0 90.5 57.9 57.8 65.2 149.0 84.9 55.3 50.2 122.5 38.9 60.9 89.8 70.4 190.1 98.2 104.2 135.8 165.0 74.2 98.7 109.6 95.2 73.8 108.4 93.8 80.6 64.2 65.3 64.9 97.6 123.9 89.6 92.9 56.6 73.3 91.5 80.9 106.6 174.6 153.8 98.9 274.8 191.3 118.1 143.7 138.5 140.0 53.4 52.7 44.7 81.6 51.5 47.5 51.1 47.9 75.3 40.6 46.3 47.3 7.3 58.4 98.2 42.3 93.3 74.2 19.6 21.6 23.7 29.5 20.5 22.9 22.5 21.0 22.3 24.3 21.7 24.8 36.2 48.1 29.5 18.3 33.8 39.8 41.4 131.8 24.5 36.0 23.5 27.2 61.8 40.0 73.9 27.6 14.6 172.2 34.4 22.5 66.5 113.9 118.9 32.3 33.9 48.5 8.4 64.6 27.9 96.4 110.6 49.7 27.5 24.9 56.4 35.5 34.2 48.5 134.6 26.9 25.1 36.9 93.6 48.5 40.4 33.2 58.4 46.1 32.0 15.9 62.4 69.5 40.2 21.1 32.8 87.3 38.5 64.3 45.0 34.7 36.9 88.8 52.5 49.1 59.2 43.7 105.2 96.3 47.2 23.6 42.9 231.8 39.5 49.1 32.0 42.9 PSMC6 p42 ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: AB_2678188" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" "unprognostic (9.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-2)" "unprognostic (4.26e-3)" "unprognostic (3.14e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.79e-2)" "unprognostic (3.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.52e-2)" "unprognostic (5.00e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (4.67e-1)" 43.4 48.4 38.8 47.3 39.2 44.1 58.1 41.2 54.0 44.0 37.4 52.2 50.0 47.6 49.2 65.1 49.2 36.5 78.7 39.8 42.1 65.9 87.1 39.6 55.4 41.1 41.0 51.0 43.7 59.9 5.5 54.9 42.0 45.3 54.3 60.1 37.9 45.6 118.1 44.6 46.6 56.8 41.5 38.8 46.5 31.4 41.0 56.3 54.3 106.7 67.0 57.2 7.9 44.1 182.0 115.0 135.4 99.0 92.4 95.8 146.0 139.3 133.1 220.8 165.1 142.6 143.5 156.8 169.8 121.6 111.5 134.0 173.9 121.9 230.6 151.2 74.5 115.0 91.3 153.5 111.0 164.9 106.8 71.8 118.4 112.1 111.6 120.1 141.2 77.4 174.2 64.7 161.8 163.2 129.5 111.8 108.7 170.1 153.8 108.4 237.2 70.7 144.6 178.5 96.0 71.2 123.8 76.5 122.3 120.8 156.4 117.0 108.9 121.2 171.0 95.8 145.2 45.6 127.0 175.8 79.1 110.5 112.9 77.5 62.4 67.0 51.2 71.9 59.5 63.4 62.7 56.4 73.9 56.4 59.6 59.0 52.7 55.6 73.0 38.5 85.4 75.4 38.8 39.2 41.2 54.0 39.8 42.1 41.1 41.0 42.0 41.5 41.0 44.1 81.2 70.5 58.9 23.5 74.2 86.2 141.9 187.1 50.1 65.5 55.3 51.3 76.6 62.9 140.6 57.0 68.8 162.2 69.4 73.5 135.0 131.0 30.4 92.8 75.3 78.2 70.4 85.2 37.4 106.9 139.9 72.1 38.7 96.3 67.7 68.7 50.0 84.4 92.1 62.2 39.0 58.9 109.9 71.3 67.9 19.9 67.1 61.4 80.0 20.6 90.9 64.6 52.5 38.2 46.7 116.2 46.2 65.5 64.0 85.2 72.5 140.2 116.4 107.6 72.3 66.5 130.6 63.4 82.8 48.9 72.0 237.5 65.0 79.7 73.4 116.6 PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" 37.3 38.2 21.9 31.7 26.1 20.1 29.0 21.9 33.7 26.3 20.9 34.8 35.5 37.4 25.6 41.5 24.3 20.3 51.3 27.5 28.5 34.1 42.1 27.0 28.8 26.9 24.9 19.2 17.3 72.7 32.9 36.8 28.3 29.7 36.8 25.4 25.8 33.4 136.3 34.9 29.3 44.9 24.5 25.2 27.9 29.0 24.5 36.6 27.4 81.6 38.3 37.3 27.8 24.4 103.9 113.1 120.6 93.8 122.2 88.7 115.4 135.3 139.4 133.4 134.0 136.5 97.6 80.0 123.3 150.5 138.0 95.0 169.4 125.0 174.3 124.3 93.3 148.7 81.6 155.5 62.9 133.3 119.4 76.5 57.8 142.4 73.9 73.4 159.6 70.3 212.1 56.8 158.7 100.3 103.0 68.3 157.8 100.1 89.3 86.0 190.4 77.7 96.5 104.0 78.8 74.1 108.7 94.1 65.7 120.6 75.3 74.7 152.3 101.4 110.8 126.0 129.8 48.6 80.2 140.4 162.7 100.0 123.4 34.6 27.8 18.8 25.1 39.0 27.3 21.0 25.8 23.8 30.9 17.2 19.2 22.9 12.5 35.9 42.5 18.9 32.3 25.7 21.9 26.1 21.9 33.7 27.5 28.5 26.9 24.9 28.3 24.5 24.5 24.4 51.9 51.3 48.5 77.7 32.9 33.1 37.7 57.0 19.9 46.4 23.0 25.8 125.4 31.5 53.0 33.1 41.7 119.2 27.0 63.6 17.6 83.9 6.2 51.2 67.5 51.7 39.4 61.6 100.0 102.2 101.4 54.6 42.3 60.9 103.9 67.8 30.0 86.9 72.3 90.9 96.0 30.0 57.0 44.2 23.5 9.9 34.8 49.8 17.8 54.4 62.6 46.6 29.9 67.3 93.1 98.6 26.2 45.9 49.4 46.5 46.9 32.1 66.9 53.2 72.3 54.6 128.2 247.9 158.8 39.2 33.1 167.5 36.6 65.5 42.9 38.8 QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA amidotransferase subunit QRSL1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "memory B-cell: 86.4;naive B-cell: 71.0" "Lineage enriched" "Detected in all" 7 "B-cells: 86.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" 5.0 5.7 4.0 8.6 5.2 6.4 7.4 4.7 5.0 4.8 5.8 8.2 7.8 6.3 6.1 5.7 5.4 4.8 10.1 4.1 4.5 9.3 7.8 4.6 15.9 4.6 4.5 5.6 6.0 9.4 4.3 5.7 5.0 5.3 9.1 8.4 6.1 5.6 19.4 5.9 8.9 5.8 4.1 10.5 6.7 6.6 4.5 8.2 9.2 21.3 15.5 5.7 4.9 7.4 9.0 9.1 12.3 17.8 7.8 9.7 17.3 10.0 10.2 13.1 13.0 10.7 7.1 29.7 8.9 11.2 13.5 15.5 18.6 12.1 16.4 14.2 14.1 14.5 9.7 11.1 12.2 33.2 12.5 9.6 18.6 14.0 20.6 9.9 9.5 18.4 26.8 9.4 11.0 10.1 10.7 16.1 12.9 15.6 10.5 28.9 15.8 7.5 14.3 10.2 10.7 11.0 8.0 18.4 15.3 10.7 12.1 25.3 9.3 9.2 7.6 10.0 15.7 5.4 8.3 17.2 12.6 22.1 14.0 5.0 6.4 1.0 6.4 9.6 6.3 86.4 7.1 5.6 10.7 71.0 6.6 6.4 1.6 7.0 13.0 8.5 8.5 5.7 4.0 5.2 4.7 5.0 4.1 4.5 4.6 4.5 5.0 4.1 4.5 7.4 9.0 19.2 12.5 20.2 64.6 4.0 8.4 12.8 6.2 14.9 10.3 6.1 24.8 7.2 9.3 11.0 16.7 21.5 12.3 11.0 17.6 15.4 15.5 28.2 12.0 10.8 17.4 13.7 14.6 18.4 23.0 9.9 15.3 14.8 18.9 15.3 8.2 14.6 12.9 3.3 18.9 11.2 14.2 12.4 6.1 8.4 8.4 10.0 8.8 12.2 18.3 9.9 19.6 22.6 26.5 14.2 8.3 9.1 13.2 9.3 12.2 19.5 19.9 19.1 0.0 10.0 10.0 25.6 14.2 12.2 5.4 12.3 14.3 21.1 18.7 8.9 RABL3 MGC23920 ENSG00000144840 "RAB, member of RAS oncogene family like 3" Q5HYI8 3 120684938-120742993 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035150, HPA035151, HPA069861" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA035150: AB_2674493, HPA035151: AB_10601154, HPA069861: " "unprognostic (1.69e-2)" "unprognostic (5.10e-2)" "unprognostic (8.32e-2)" "unprognostic (3.96e-2)" "unprognostic (1.88e-1)" "unprognostic (7.22e-2)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (2.94e-1)" "unprognostic (2.11e-3)" "unprognostic (2.78e-1)" "prognostic favorable (2.79e-5)" "unprognostic (2.33e-1)" "unprognostic (6.15e-2)" "unprognostic (8.44e-3)" "unprognostic (3.65e-1)" 10.8 16.1 2.3 5.6 2.5 5.3 8.8 2.6 4.1 7.0 2.6 8.1 5.5 7.0 2.7 7.9 5.9 5.7 7.3 2.1 3.1 9.8 9.7 5.6 5.9 3.0 2.8 9.2 6.4 11.8 6.3 6.9 2.9 6.9 8.6 5.8 6.9 6.5 13.8 6.3 6.0 6.2 2.7 5.6 7.1 4.2 2.4 6.4 12.3 11.9 7.3 7.3 7.9 3.7 20.6 17.8 12.6 3.9 11.7 17.0 11.4 18.8 13.8 10.0 8.3 12.6 6.5 17.3 8.5 15.4 17.6 7.1 14.0 9.2 18.3 14.8 5.9 16.0 12.9 15.7 8.1 31.2 9.1 8.4 11.2 8.9 10.7 11.6 15.1 9.4 14.2 9.7 12.8 20.8 18.2 3.0 6.4 19.9 8.6 7.7 17.4 6.6 9.6 10.0 5.8 4.5 9.2 5.5 5.4 4.8 10.5 9.8 22.1 6.5 7.5 4.8 17.1 5.4 7.9 13.6 16.7 25.4 8.4 3.7 3.6 2.6 4.6 5.6 3.6 3.2 4.5 5.1 6.5 2.6 3.8 4.4 3.7 5.6 3.1 3.4 5.3 3.4 2.3 2.5 2.6 4.1 2.1 3.1 3.0 2.8 2.9 2.7 2.4 3.7 17.6 9.6 11.7 14.7 11.6 6.4 17.2 17.3 11.4 39.8 13.7 10.0 14.3 12.8 16.7 9.2 116.7 13.3 7.7 13.1 7.9 15.2 25.5 22.3 11.9 12.8 5.4 10.7 11.7 16.2 18.0 13.8 9.7 14.2 8.2 10.4 8.2 18.1 14.7 8.4 10.2 12.7 16.2 10.6 7.2 9.8 5.9 12.0 10.6 2.8 11.4 19.2 9.2 7.5 17.1 14.6 15.8 6.0 11.3 12.2 9.6 26.4 15.7 20.0 0.0 16.5 10.4 26.9 8.5 10.5 11.1 22.0 10.0 16.6 12.1 15.4 RAVER2 "FLJ10770, KIAA1579" ENSG00000162437 "Ribonucleoprotein, PTB binding 2" Q9HCJ3 1 64745095-64833232 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Distal enterocytes: 60.1;Inhibitory neurons: 40.4;Oligodendrocyte precursor cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "basophil: 6.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045785 Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA045785: AB_10964058" "unprognostic (8.02e-2)" "unprognostic (5.23e-2)" "unprognostic (4.23e-3)" "unprognostic (2.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.89e-2)" "unprognostic (2.22e-3)" "unprognostic (1.23e-2)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (6.56e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.14e-6)" "unprognostic (1.74e-1)" "unprognostic (3.50e-2)" "unprognostic (1.41e-1)" "unprognostic (5.09e-2)" 4.7 8.2 12.8 4.2 12.1 9.5 8.2 15.0 12.4 7.7 12.6 23.6 24.2 7.8 5.7 9.4 7.5 11.3 12.6 13.3 10.9 7.7 1.6 8.3 2.0 9.7 12.2 6.4 7.3 16.2 12.3 7.3 10.3 12.0 26.8 15.1 15.5 10.3 22.2 6.7 26.1 9.3 10.4 4.3 12.5 2.7 13.3 8.3 6.1 17.7 4.1 6.5 7.4 9.3 16.7 5.1 15.2 16.7 2.7 2.3 4.1 3.6 6.5 7.3 8.2 13.6 7.3 0.1 8.2 3.8 16.6 12.4 15.7 10.9 8.9 0.1 17.3 20.2 13.7 12.2 5.1 27.5 0.2 6.8 9.8 0.5 7.5 16.9 12.2 16.6 4.5 16.3 0.6 6.2 9.2 5.6 18.8 13.1 13.3 31.1 23.9 6.7 8.0 12.3 11.5 25.6 16.4 0.0 16.0 14.3 12.6 4.3 4.6 6.8 10.9 6.8 13.1 12.3 14.9 7.0 4.1 0.1 6.4 6.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 12.8 12.1 15.0 12.4 13.3 10.9 9.7 12.2 10.3 10.4 13.3 9.3 9.2 6.4 13.5 72.8 0.6 8.0 7.0 3.9 8.0 7.1 7.2 6.0 24.4 11.5 8.3 1.8 14.6 0.2 1.1 60.1 0.0 3.4 9.8 5.7 2.5 10.6 18.0 4.2 29.0 5.2 0.3 6.3 11.2 6.5 1.3 7.1 6.8 0.3 0.6 0.0 40.4 30.7 4.1 4.8 3.3 16.8 6.5 2.0 3.6 22.5 0.3 26.1 0.0 40.2 1.8 2.7 20.5 8.2 2.3 6.6 26.9 2.1 6.1 3.7 0.0 6.2 5.5 3.1 3.2 8.5 5.8 0.3 1.5 1.7 27.8 7.3 RBM18 MGC2734 ENSG00000119446 "RNA binding motif protein 18" Q96H35 9 122237622-122264840 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057281, HPA077955" Uncertain Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA057281: AB_2683394, HPA077955: " "unprognostic (1.75e-2)" "unprognostic (7.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (9.39e-3)" "unprognostic (7.27e-3)" "unprognostic (2.79e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "prognostic favorable (8.00e-7)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 9.0 9.5 7.4 6.4 7.9 11.7 16.4 8.0 10.1 8.9 7.3 7.5 7.0 8.8 10.3 7.7 7.4 7.6 13.5 7.8 8.8 11.4 8.4 7.2 8.1 8.2 7.9 9.5 6.9 11.9 5.7 10.4 8.6 11.1 8.1 11.5 7.9 8.3 20.7 6.8 6.1 8.7 8.0 8.0 8.5 3.6 8.0 9.5 10.0 23.1 7.6 8.7 5.4 8.4 8.1 8.3 11.2 12.4 16.1 19.8 9.7 18.0 14.7 12.1 11.2 9.6 7.8 14.1 7.7 11.8 13.3 18.5 17.6 18.7 15.1 14.5 8.0 10.5 12.6 8.2 18.1 21.1 14.0 17.0 20.8 12.7 25.8 12.1 17.6 11.3 14.6 10.7 18.3 8.8 11.1 13.0 8.7 27.2 13.7 9.7 23.2 19.3 16.9 9.0 23.3 12.3 13.6 18.9 21.3 8.8 11.0 11.8 9.8 11.3 6.4 18.3 18.0 15.5 30.7 11.7 18.6 12.9 13.8 4.5 6.2 11.4 6.3 7.2 6.1 5.8 5.5 6.2 6.5 4.0 5.7 6.0 6.5 5.4 9.7 4.6 6.4 5.8 7.4 7.9 8.0 10.1 7.8 8.8 8.2 7.9 8.6 8.0 8.0 8.4 19.7 32.1 12.8 2.0 18.3 21.7 11.7 28.5 19.9 12.4 27.2 20.7 51.6 10.0 23.1 25.8 2.1 32.8 23.3 17.2 27.4 23.2 75.0 14.7 19.9 21.6 19.7 28.4 9.1 16.2 44.7 15.9 13.3 16.4 17.7 14.1 13.6 13.7 27.7 3.3 12.9 16.5 34.6 21.0 17.2 76.9 13.4 18.4 19.6 4.7 20.6 16.9 27.8 6.0 10.7 23.0 18.7 17.0 16.4 20.8 14.8 26.6 19.8 14.7 19.7 15.2 25.4 19.7 22.1 16.5 25.9 56.9 23.5 16.7 14.2 20.7 RBM41 FLJ11016 ENSG00000089682 "RNA binding motif protein 41" Q96IZ5 X 107064420-107118823 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042881 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles, Cytosol" "HPA042881: AB_10794536" "unprognostic (1.07e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-2)" "unprognostic (1.98e-2)" "unprognostic (2.19e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.78e-1)" "unprognostic (1.40e-1)" "unprognostic (2.80e-2)" "unprognostic (1.92e-1)" 4.6 5.8 2.6 5.0 3.0 3.5 5.7 5.7 3.7 4.2 5.1 5.5 7.7 6.1 6.5 5.6 5.0 4.5 5.5 3.0 2.8 6.8 8.3 4.7 5.8 3.9 3.4 5.5 4.2 9.3 3.4 5.4 3.4 5.5 6.5 5.8 4.5 5.0 6.4 7.1 6.9 5.6 3.2 5.3 5.0 7.3 3.2 6.6 6.9 8.0 6.2 5.0 4.1 3.8 16.9 13.3 8.4 6.8 5.5 9.5 9.7 9.8 9.6 7.1 9.5 8.9 13.8 9.3 18.0 7.2 12.4 13.7 12.3 9.2 10.8 11.5 18.1 11.3 25.2 11.0 6.2 11.6 8.5 6.7 17.7 8.6 8.6 9.9 10.8 8.5 19.8 12.5 8.7 8.2 9.9 6.6 12.4 9.3 15.1 7.9 7.0 8.0 10.5 10.5 6.9 10.9 12.2 8.7 7.9 11.4 8.0 5.4 10.6 9.8 5.7 11.7 7.8 5.8 11.6 9.9 5.5 5.2 7.6 10.5 5.2 8.3 4.5 2.7 2.7 5.1 3.9 4.6 3.5 4.3 2.9 1.9 0.7 6.6 2.9 3.6 3.9 2.3 2.6 3.0 5.7 3.7 3.0 2.8 3.9 3.4 3.4 3.2 3.2 3.8 9.6 12.8 17.0 29.0 11.6 5.2 6.6 8.5 12.0 20.3 7.6 6.7 23.2 11.5 8.3 7.3 27.1 8.7 17.4 10.9 1.9 14.8 8.0 27.1 10.1 9.8 7.8 21.0 38.3 7.8 5.3 10.1 8.2 11.6 13.3 19.5 5.3 10.2 6.6 11.8 46.5 8.6 4.1 10.7 4.6 2.3 14.3 12.5 5.4 45.9 11.7 7.4 14.4 50.8 53.4 13.6 11.9 11.7 12.6 5.6 22.0 9.0 13.1 20.2 0.0 14.7 12.4 11.7 8.0 9.0 7.4 4.5 9.7 13.1 11.4 6.2 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favorable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favorable (7.89e-5)" 8.6 7.0 9.5 7.9 10.2 17.0 16.8 12.6 13.0 9.0 7.7 12.1 8.7 9.6 6.9 7.2 11.9 6.8 16.8 9.4 10.6 16.2 12.3 10.0 9.5 8.9 10.4 14.5 8.3 12.6 5.8 10.0 9.9 10.9 13.2 14.8 12.9 10.1 16.5 5.6 8.6 11.6 9.9 11.5 8.9 13.6 10.7 12.7 18.9 23.6 12.6 7.6 4.7 10.7 9.8 5.0 14.6 13.8 15.1 13.1 8.4 6.5 15.1 13.2 15.4 13.8 11.9 16.2 12.0 9.4 13.1 5.8 37.6 11.5 19.9 13.4 12.3 21.2 9.2 17.9 13.0 28.9 11.2 12.2 14.1 15.2 14.2 15.9 27.0 20.8 19.9 16.2 30.9 15.8 26.7 11.5 24.5 26.9 8.7 14.2 34.4 13.9 20.4 16.7 22.6 12.4 10.7 24.8 28.2 15.9 14.0 12.9 10.8 8.6 8.5 7.8 11.1 17.0 13.0 22.8 10.5 20.2 14.0 27.5 9.2 9.7 4.3 5.7 7.6 4.6 5.4 5.2 8.0 2.1 3.9 5.5 4.0 5.5 5.6 4.1 5.7 4.7 9.5 10.2 12.6 13.0 9.4 10.6 8.9 10.4 9.9 9.9 10.7 10.7 22.2 19.2 10.3 28.4 25.4 40.7 32.3 47.1 39.3 35.0 38.5 25.9 56.8 24.3 23.5 23.9 20.9 31.6 31.2 21.9 68.4 30.3 37.3 11.9 17.1 22.3 13.8 21.8 31.2 22.5 23.2 24.6 21.9 17.3 5.1 23.8 25.4 23.0 19.0 23.5 32.3 23.4 38.7 37.5 26.8 59.8 22.4 27.4 28.4 22.5 23.9 32.0 24.7 31.7 41.0 26.5 22.6 25.2 19.7 36.6 24.6 69.4 13.5 21.7 32.9 20.9 27.3 72.8 41.7 28.1 31.0 33.8 32.9 35.2 27.6 26.3 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (2.10e-1)" "unprognostic (3.22e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.09e-4)" "unprognostic (2.22e-1)" "unprognostic (5.42e-2)" "unprognostic (1.51e-3)" "unprognostic (1.81e-3)" "unprognostic (9.77e-2)" "prognostic favorable (8.55e-13)" "unprognostic (2.46e-2)" "unprognostic (1.68e-1)" "unprognostic (3.03e-3)" "unprognostic (1.18e-1)" 9.8 10.4 7.5 8.7 6.9 5.6 8.5 6.6 6.7 7.9 3.4 12.9 10.7 8.8 7.8 8.6 8.3 6.0 12.9 7.3 7.8 11.5 7.4 9.1 7.5 5.8 6.3 10.1 10.7 19.1 10.5 9.3 6.0 8.7 13.4 7.8 11.0 11.4 17.3 9.4 11.6 9.8 5.6 7.4 10.3 6.4 8.0 8.9 12.2 18.6 9.6 8.0 6.5 5.9 18.0 16.6 18.9 15.8 17.3 18.6 11.1 13.9 20.1 18.9 17.4 14.2 6.7 13.9 9.7 17.8 34.9 9.9 18.3 26.2 15.5 18.6 10.7 11.9 32.9 10.7 16.3 13.0 16.1 18.8 32.8 19.9 24.0 27.0 22.7 10.6 8.2 7.5 17.3 8.5 4.0 4.7 7.9 14.7 19.2 13.2 13.5 9.9 16.5 12.4 13.8 14.9 12.3 17.0 11.2 16.6 14.2 6.2 29.0 15.1 18.9 10.5 11.8 11.1 16.5 14.3 21.5 5.4 19.7 1.1 0.2 0.4 0.7 0.4 1.1 0.8 0.5 0.8 0.1 1.0 0.6 0.7 0.7 1.1 0.6 0.6 0.5 0.2 7.5 6.9 6.6 6.7 7.3 7.8 5.8 6.3 6.0 5.6 8.0 5.9 13.9 6.4 12.6 0.0 23.4 5.7 24.5 14.8 9.1 40.8 15.0 10.0 16.6 18.6 15.8 27.6 20.9 10.9 19.1 46.1 13.7 20.1 17.5 9.8 8.3 14.9 43.3 8.6 0.2 17.6 10.6 7.5 18.8 14.9 5.7 33.4 16.1 16.4 7.5 16.8 0.1 26.0 22.4 7.7 6.1 36.8 8.4 5.7 1.8 0.0 11.1 18.8 25.7 0.0 0.1 20.6 38.3 10.9 15.2 25.3 36.3 14.2 17.7 22.3 6.6 11.8 9.3 16.6 6.1 8.1 5.3 10.3 16.4 7.1 28.9 28.8 RIOX2 "FLJ14393, JMJD10, mdig, MINA, MINA53, NO52" ENSG00000170854 "Ribosomal oxygenase 2" Q8IUF8 3 97941818-97972457 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.7;Distal tubular cells: 49.0;Endometrial ciliated cells: 25.7;Extravillous trophoblasts: 43.5;Syncytiotrophoblasts: 31.2;Theca cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007603, HPA008080, CAB013458" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "CAB013458: AB_2533432, HPA007603: AB_1853957, HPA008080: AB_1853960" "prognostic unfavorable (4.41e-4)" "unprognostic (8.64e-2)" "unprognostic (1.59e-3)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.53e-3)" "unprognostic (1.64e-3)" "unprognostic (8.68e-2)" "unprognostic (9.68e-2)" "unprognostic (5.34e-2)" "unprognostic (1.56e-3)" "unprognostic (6.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (3.44e-3)" "unprognostic (1.76e-1)" 14.6 9.7 9.8 14.5 11.3 2.2 13.9 9.5 11.2 11.6 8.3 12.4 6.9 10.7 10.6 22.3 10.4 7.3 10.1 9.5 12.3 14.4 14.3 11.0 14.2 12.4 12.4 10.4 18.2 10.8 10.2 15.6 12.0 10.4 12.3 16.8 19.8 9.6 32.0 17.8 10.3 10.4 12.9 8.4 12.8 6.7 10.9 6.9 46.4 11.3 15.0 16.4 15.5 13.6 42.6 27.8 9.1 17.4 20.5 30.3 22.8 20.1 14.3 22.0 18.5 18.6 22.8 59.7 21.2 25.1 34.3 24.3 28.9 28.2 32.5 109.9 13.8 19.2 13.5 19.1 33.4 37.1 7.0 24.5 38.8 17.6 44.4 13.1 23.9 26.4 26.2 23.3 22.1 11.5 29.7 14.5 19.9 47.3 34.4 0.0 32.2 58.7 21.4 24.1 49.6 17.6 25.7 28.7 34.4 10.1 24.7 15.3 16.3 22.9 24.0 13.7 39.9 37.7 18.3 55.5 29.1 37.8 23.8 1.9 13.2 0.7 10.3 11.9 15.8 15.9 14.9 12.0 16.9 13.3 15.0 12.5 0.8 10.8 15.8 26.0 15.2 10.5 9.8 11.3 9.5 11.2 9.5 12.3 12.4 12.4 12.0 12.9 10.9 13.6 18.3 9.6 14.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 14.9 11.2 0.0 0.0 10.5 7.3 0.0 33.7 5.7 0.0 49.0 16.4 0.0 25.7 14.9 5.8 0.0 0.0 0.0 13.2 43.5 7.3 0.0 12.6 2.5 20.2 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.5 0.0 0.0 11.6 13.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 31.2 2.2 24.8 0.0 0.0 RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Centrosome "Actin filaments" "HPA026495: AB_1848414" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-1)" "prognostic favorable (8.51e-4)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (4.71e-3)" "unprognostic (3.47e-1)" 35.6 26.1 25.8 20.9 30.1 24.7 24.3 30.4 27.8 15.5 25.3 26.7 28.7 17.6 19.8 29.4 21.1 22.5 63.0 23.0 29.5 51.7 56.8 23.4 30.3 29.8 29.7 17.0 17.5 26.3 12.9 18.9 30.0 21.2 29.0 30.9 16.4 20.7 71.7 32.8 29.2 20.2 28.3 25.2 30.6 26.4 29.6 23.0 50.4 70.5 31.5 20.1 16.3 30.5 64.0 27.1 31.3 17.8 60.3 97.8 38.5 45.9 41.1 35.8 34.6 32.2 39.9 76.2 38.1 38.2 33.2 61.0 39.8 46.0 42.1 64.6 31.9 40.2 32.8 82.1 32.1 18.4 1.0 53.3 42.6 47.6 72.9 63.9 81.6 44.3 42.4 40.7 57.5 57.3 65.1 8.6 15.9 111.3 67.5 36.6 43.6 78.9 42.5 39.3 14.8 32.8 38.2 149.2 67.6 32.5 83.9 33.6 44.6 39.5 64.0 50.8 28.2 52.4 46.5 59.7 51.2 28.7 54.4 16.4 38.5 94.2 26.6 50.7 31.1 42.2 27.1 31.3 45.2 30.8 22.3 29.0 15.5 39.0 70.3 51.3 43.2 30.7 25.8 30.1 30.4 27.8 23.0 29.5 29.8 29.7 30.0 28.3 29.6 30.5 24.0 41.7 39.0 38.8 23.8 13.5 13.2 40.1 22.2 14.5 16.8 15.0 117.3 20.0 42.4 20.2 16.7 42.5 29.9 22.2 49.0 42.9 97.8 28.3 26.6 24.3 10.2 27.3 22.5 53.0 57.1 24.0 32.1 24.8 1.3 18.9 21.8 57.7 53.7 20.2 29.9 20.6 18.3 40.1 14.8 77.1 13.1 28.3 16.0 33.7 48.5 27.4 21.6 42.3 51.9 45.8 17.2 9.1 21.8 9.2 45.7 73.0 34.4 21.5 0.0 19.9 32.9 65.7 33.5 31.0 15.5 28.5 21.6 53.1 26.9 15.2 RNF14 "ARA54, HFB30, TRIAD2" ENSG00000013561 "Ring finger protein 14" Q9UBS8 5 141958328-141990292 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008716, HPA064746" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA008716: AB_1856337, HPA064746: " "unprognostic (7.45e-3)" "unprognostic (1.38e-1)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.22e-2)" "unprognostic (7.42e-2)" "unprognostic (7.92e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.71e-4)" "unprognostic (6.89e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.06e-2)" 48.4 51.8 31.5 26.0 32.7 20.2 45.6 32.7 42.8 36.6 30.6 40.7 33.2 33.6 43.2 32.6 29.7 32.6 71.2 33.3 35.6 65.3 67.6 30.2 32.3 35.3 38.2 32.3 37.2 104.0 23.7 39.8 36.3 44.0 41.2 40.4 37.1 40.2 66.7 23.5 36.4 43.3 33.4 28.9 35.4 74.5 36.5 36.7 55.1 85.8 33.7 32.1 23.4 33.7 38.3 62.5 43.1 85.1 75.7 78.8 29.0 76.8 42.6 52.8 58.1 52.4 43.4 67.1 87.5 79.3 79.4 20.6 55.6 75.4 47.0 51.1 48.5 42.9 30.2 24.0 83.2 47.7 36.9 59.7 64.9 70.3 87.6 45.6 66.2 46.0 53.0 91.7 109.4 45.7 46.6 15.3 18.3 46.2 71.0 30.2 47.8 73.8 71.7 65.2 47.5 38.3 67.3 121.3 133.2 47.8 85.0 36.7 69.3 69.6 22.6 33.2 74.0 56.8 72.1 61.8 59.7 57.4 87.9 79.6 22.0 23.2 26.9 26.9 26.0 19.5 23.2 26.9 27.4 18.1 17.6 25.9 5.5 30.1 33.9 28.9 29.1 19.7 31.5 32.7 32.7 42.8 33.3 35.6 35.3 38.2 36.3 33.4 36.5 33.7 18.1 9.6 19.3 12.7 12.5 10.7 15.9 19.6 11.4 20.2 18.4 15.0 45.4 11.5 18.1 22.0 16.7 29.1 13.3 22.9 68.4 29.2 257.1 14.1 20.8 21.7 15.0 59.1 25.1 24.9 26.1 18.2 18.3 16.4 22.2 32.0 20.7 33.1 24.5 23.5 22.9 14.9 24.4 29.7 10.4 39.3 19.3 17.1 32.0 13.1 14.8 28.7 29.9 15.6 18.6 26.3 14.0 33.4 13.5 19.2 28.3 50.5 15.8 16.3 39.5 15.8 23.0 38.7 25.8 15.6 10.5 60.5 16.4 25.0 15.0 15.0 RPL7L1 dJ475N16.4 ENSG00000146223 "Ribosomal protein L7 like 1" Q6DKI1 6 42879616-42889925 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046049, HPA050478" Approved Nucleoli,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoli, Mitochondria" "HPA046049: AB_10964167, HPA050478: AB_2681138" "unprognostic (1.03e-3)" "unprognostic (4.37e-2)" "unprognostic (3.37e-1)" "unprognostic (7.97e-2)" "unprognostic (7.73e-3)" "unprognostic (4.26e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (2.56e-1)" "unprognostic (2.98e-2)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.06e-1)" "unprognostic (7.31e-3)" "unprognostic (4.58e-2)" 37.2 39.5 26.1 31.7 28.0 22.6 40.2 27.2 33.5 28.2 20.6 30.4 25.4 30.0 34.0 35.4 34.2 21.5 30.8 28.7 27.3 37.7 48.4 25.2 34.4 23.7 24.1 33.6 32.2 45.4 29.1 31.7 24.2 33.7 34.1 20.0 28.0 27.7 45.5 33.9 23.4 33.4 24.0 27.1 28.6 16.1 26.6 37.1 35.9 44.4 42.8 35.6 27.0 25.9 155.6 48.4 84.2 135.5 77.5 99.5 57.1 121.3 87.8 115.0 94.6 120.4 57.6 231.4 107.0 102.6 93.4 72.5 193.4 147.6 189.4 121.9 144.6 123.7 64.5 109.9 85.2 192.5 91.6 102.5 110.6 151.0 144.7 77.5 114.7 100.2 243.1 77.6 106.2 113.3 110.5 124.2 85.1 472.2 70.3 124.9 94.3 147.1 89.7 96.6 160.1 97.8 103.7 78.2 131.3 66.1 105.0 183.1 110.1 110.5 91.9 88.4 211.3 96.7 163.8 343.2 61.7 178.7 117.7 7.3 13.1 12.4 16.0 15.8 20.3 14.9 15.7 17.0 12.5 17.4 16.5 16.0 2.8 19.7 14.9 14.5 14.3 13.6 26.1 28.0 27.2 33.5 28.7 27.3 23.7 24.1 24.2 24.0 26.6 25.9 56.2 76.9 103.0 12.7 69.3 57.1 89.3 70.6 67.7 62.6 49.2 61.8 42.2 61.5 71.2 42.3 33.3 88.2 77.7 23.9 86.1 92.2 12.6 68.4 96.6 71.6 94.4 73.0 25.9 66.9 84.1 67.5 42.8 44.9 51.2 120.6 51.8 65.0 53.0 72.3 23.3 44.4 54.9 45.0 34.4 12.5 79.2 44.5 30.2 8.4 75.8 78.6 64.9 12.5 15.6 81.3 30.8 71.5 56.1 83.8 25.1 79.8 71.3 69.7 52.6 89.9 64.0 54.9 75.6 65.8 60.2 80.0 65.6 117.8 52.5 58.9 RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 236.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 21.1 18.8 6.9 33.7 10.2 16.2 14.8 12.7 12.8 16.1 8.5 32.8 24.1 17.5 8.5 18.7 15.1 26.9 21.1 8.7 9.4 19.5 45.0 32.3 31.3 8.4 10.0 10.6 17.2 59.4 5.9 19.5 8.5 19.9 31.8 15.7 13.2 18.0 51.8 15.0 27.6 27.8 8.7 29.2 21.1 5.5 10.6 32.9 21.2 40.3 32.6 34.2 8.5 8.0 44.9 77.0 28.4 14.8 27.1 47.3 8.6 38.0 57.4 27.8 37.7 87.7 56.2 29.3 12.8 40.0 40.5 30.9 32.8 32.2 51.1 24.8 26.1 34.6 46.2 236.8 27.7 67.8 34.2 30.3 25.1 43.5 54.4 24.3 101.9 30.4 23.1 81.0 29.4 21.2 44.2 20.7 20.6 57.8 45.9 23.3 60.0 33.8 23.9 36.9 13.1 12.8 51.1 15.3 54.4 35.3 0.1 20.0 57.3 30.1 20.8 96.3 21.7 64.3 42.1 32.1 56.9 33.1 72.6 11.9 3.8 7.9 4.7 5.3 8.3 2.4 5.4 5.2 5.6 3.2 3.7 4.5 5.8 6.6 6.0 6.7 2.9 2.2 6.9 10.2 12.7 12.8 8.7 9.4 8.4 10.0 8.5 8.7 10.6 8.0 60.6 44.8 67.5 31.6 34.8 54.4 37.0 21.2 10.2 37.8 20.4 10.8 22.9 34.3 41.1 16.5 22.9 4.0 70.0 63.5 3.9 26.3 0.4 10.8 24.0 61.1 25.0 19.1 142.2 30.5 6.7 31.6 24.5 26.1 44.3 8.3 34.6 65.4 22.6 13.5 108.4 59.1 28.5 40.8 104.3 1.5 13.1 62.6 37.4 126.5 53.7 27.5 46.4 116.6 27.0 37.4 57.9 21.1 25.5 56.6 33.5 25.1 23.3 9.7 19.7 41.5 21.3 6.4 8.7 13.8 55.5 3.6 66.0 14.2 61.1 63.8 RRAS2 TC21 ENSG00000133818 "RAS related 2" P62070 11 14277922-14364506 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010420, HPA050942" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB010420: AB_2253855, HPA050942: AB_2681285" "unprognostic (6.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (7.80e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (4.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.50e-2)" "unprognostic (4.15e-1)" "unprognostic (9.02e-2)" "unprognostic (1.05e-1)" "unprognostic (6.80e-2)" "unprognostic (1.63e-1)" 30.8 14.1 8.0 16.1 8.0 5.2 21.2 9.7 10.7 21.7 14.9 22.3 20.8 19.7 9.2 15.4 14.2 11.9 44.4 12.0 10.5 39.3 39.1 22.9 28.3 7.0 8.1 18.3 18.2 17.2 8.5 29.4 8.0 20.1 18.7 12.1 18.0 19.3 40.8 12.1 39.5 18.0 6.3 16.3 17.7 25.1 10.4 14.4 29.0 34.0 37.7 23.4 14.0 6.3 89.3 38.2 35.7 30.8 122.0 121.1 52.8 309.1 160.7 260.5 328.1 78.0 108.7 102.2 46.8 209.0 84.3 97.1 61.0 110.8 260.5 88.7 49.6 6.8 21.5 62.4 133.6 0.3 0.7 129.5 205.0 104.2 331.2 106.5 131.7 24.8 45.9 0.2 229.3 43.5 21.5 5.6 98.3 18.2 31.4 19.0 118.5 1.9 133.7 48.8 9.7 18.4 74.7 46.0 42.5 119.9 30.6 6.2 303.1 139.6 74.0 272.1 85.1 0.2 0.2 48.4 56.0 0.1 29.0 2.1 0.0 0.0 5.5 0.0 2.4 11.8 1.0 2.8 0.0 6.6 0.5 2.1 0.4 3.8 0.0 0.2 0.0 0.9 8.0 8.0 9.7 10.7 12.0 10.5 7.0 8.1 8.0 6.3 10.4 6.3 6.6 19.2 18.9 14.4 57.8 69.3 76.2 17.7 23.9 5.5 22.6 13.7 31.5 40.0 20.6 18.4 0.0 36.5 31.2 30.5 23.5 46.5 55.2 25.8 16.0 15.2 19.1 3.2 32.8 18.4 58.0 29.7 12.8 34.7 8.9 15.6 13.6 33.4 8.2 13.5 35.4 16.0 14.2 2.4 12.0 45.2 16.4 2.3 26.6 9.4 2.0 21.7 56.7 28.6 4.9 57.1 30.1 11.3 22.0 120.3 89.9 112.9 15.0 10.1 19.7 20.7 21.4 39.5 42.1 20.3 49.9 29.0 29.5 13.3 20.8 96.5 RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, DNA replication" Oxidoreductase "Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" 11.5 21.2 10.5 11.5 12.1 7.1 12.1 13.6 11.5 12.5 26.5 15.3 15.0 11.6 15.1 11.2 13.5 11.9 16.7 10.1 13.7 24.4 22.6 22.0 20.1 13.6 12.4 12.0 13.5 45.0 10.3 13.8 13.9 15.7 15.5 21.9 10.9 13.8 30.4 11.0 10.1 11.7 14.1 14.3 9.5 9.7 12.6 10.1 39.9 34.9 19.6 11.2 5.4 16.8 15.3 26.5 30.7 18.3 43.7 41.3 24.6 34.8 41.4 18.1 21.0 9.6 11.9 97.5 31.8 38.7 18.5 5.7 15.1 35.2 25.3 15.8 16.2 24.4 10.3 20.9 35.3 7.6 50.0 53.1 66.1 20.2 30.5 43.0 51.8 16.3 18.2 14.6 59.1 15.2 13.1 14.6 17.7 16.5 19.2 8.2 12.7 20.1 43.1 17.1 7.8 15.4 17.9 9.7 21.1 76.3 25.5 17.1 39.4 27.8 53.7 19.6 9.6 15.3 15.3 88.0 41.0 11.5 30.2 15.7 6.3 7.0 2.7 5.4 3.8 6.6 2.3 3.2 7.7 8.6 2.6 2.8 23.1 4.1 11.5 2.2 1.8 3.3 10.5 12.1 13.6 11.5 10.1 13.7 13.6 12.4 13.9 14.1 12.6 16.8 16.2 57.7 29.3 10.1 33.5 19.4 8.2 11.8 34.1 13.5 17.0 9.4 22.8 20.0 23.9 40.5 14.6 13.8 13.9 7.3 25.4 6.8 2.3 36.2 11.1 14.9 29.4 3.8 14.6 8.2 5.9 14.8 6.1 11.8 11.4 11.2 18.5 23.6 12.6 10.1 17.6 9.7 10.2 26.2 39.5 1.4 14.3 23.8 17.8 20.6 18.2 24.5 7.2 16.1 12.1 5.7 5.7 14.7 9.3 10.7 8.1 22.7 39.9 18.3 6.6 16.2 16.8 13.2 14.5 26.2 18.5 4.8 12.2 8.6 12.1 6.7 RSC1A1 RS1 ENSG00000215695 "Regulator of solute carriers 1" Q92681 1 15659869-15661722 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027813, HPA028676" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Cell Junctions" "HPA027813: AB_10600308, HPA028676: AB_10600895" 3.0 1.5 0.1 2.6 0.3 4.1 1.9 0.4 1.1 1.3 1.1 1.4 0.5 1.9 0.3 4.2 1.9 1.9 3.0 0.4 0.0 4.6 8.3 2.3 2.9 0.6 0.0 1.9 1.1 2.9 0.5 3.2 0.6 2.0 2.0 2.4 0.2 1.4 0.2 0.8 1.4 3.7 0.3 0.8 1.3 2.4 0.6 2.0 2.4 4.9 4.1 2.2 1.0 1.7 4.1 4.7 5.7 3.8 6.9 4.8 7.5 3.4 5.6 9.2 8.5 7.8 6.5 9.2 3.2 7.6 4.6 2.8 14.9 4.8 11.2 6.0 3.8 8.5 9.1 8.4 1.6 12.6 4.2 3.8 0.0 15.8 8.7 2.2 5.9 6.1 23.6 8.3 6.8 4.1 6.7 0.0 6.2 2.4 2.7 5.6 8.0 3.8 2.2 7.5 4.6 1.9 6.3 2.9 4.9 4.8 4.0 1.1 5.8 4.7 8.5 4.2 2.5 2.6 5.2 15.6 1.9 3.4 3.4 0.0 0.4 0.1 0.1 0.9 0.4 0.3 0.1 0.6 0.9 0.0 0.2 0.1 0.0 0.4 0.0 0.2 0.7 0.5 0.1 0.3 0.4 1.1 0.4 0.0 0.6 0.0 0.6 0.3 0.6 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RSRC1 "BM-011, MGC12197, SFRS21, SRrp53" ENSG00000174891 "Arginine and serine rich coiled-coil 1" Q96IZ7 3 158105855-158545730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044792 Supported Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA044792: AB_10794502" "unprognostic (1.06e-2)" "unprognostic (8.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (7.40e-5)" "unprognostic (5.18e-1)" "unprognostic (1.17e-1)" "unprognostic (3.60e-3)" "unprognostic (2.91e-2)" "unprognostic (2.86e-2)" "unprognostic (5.71e-2)" "unprognostic (2.53e-3)" "unprognostic (8.84e-2)" "unprognostic (7.98e-3)" "unprognostic (3.48e-2)" "unprognostic (9.71e-2)" "unprognostic (2.71e-1)" "unprognostic (2.15e-1)" 18.5 17.1 13.2 11.8 12.0 15.1 16.4 16.9 17.2 16.0 6.2 14.8 8.7 14.2 11.6 12.7 10.7 10.2 16.0 8.0 12.7 15.9 16.5 10.6 13.7 14.5 15.5 12.8 15.6 15.6 11.6 11.8 12.6 13.1 13.5 18.7 13.5 12.3 19.3 12.9 10.2 13.8 11.0 11.8 12.1 11.3 17.6 13.2 17.0 11.0 14.2 13.6 13.4 13.8 73.6 37.3 24.1 32.1 60.7 41.4 34.1 36.2 29.3 37.8 41.5 51.8 56.8 68.6 66.9 42.9 47.2 32.8 48.4 31.8 58.3 107.6 40.4 71.0 30.4 41.3 9.3 61.5 43.2 32.3 30.0 32.4 29.1 43.4 17.7 38.8 45.4 50.2 31.6 63.7 43.2 41.5 21.4 44.3 33.4 54.7 45.4 86.1 29.5 23.8 47.4 51.7 40.7 26.6 44.6 27.1 59.2 51.7 20.3 52.6 31.6 63.3 69.4 41.0 51.0 72.6 48.5 79.5 61.2 40.4 36.3 20.3 25.1 38.6 25.9 49.5 25.6 24.3 22.0 45.5 23.9 25.7 25.4 17.7 37.2 62.3 22.4 12.9 13.2 12.0 16.9 17.2 8.0 12.7 14.5 15.5 12.6 11.0 17.6 13.8 36.0 32.1 23.1 51.6 51.1 37.3 36.1 32.3 15.4 78.1 39.4 28.7 44.9 45.8 27.0 82.8 33.3 37.5 41.1 33.2 74.3 52.6 49.9 32.8 48.4 35.5 33.0 68.8 71.3 60.5 52.8 47.5 26.0 29.9 76.5 44.0 32.2 74.5 38.3 63.9 82.4 54.9 40.7 45.6 67.6 11.0 46.3 42.4 44.4 80.6 50.0 52.2 44.3 46.3 142.2 45.8 34.2 35.7 35.4 27.7 21.8 67.8 29.7 95.6 19.7 34.8 49.5 39.5 40.4 27.4 27.4 29.6 37.4 39.8 35.9 29.3 RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266216-100292769 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm NA NA 38000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA027982: AB_10601769, HPA027990: AB_2672452, HPA028151: AB_10602099, HPA028331: " "unprognostic (4.79e-2)" "unprognostic (1.17e-2)" "unprognostic (3.97e-2)" "unprognostic (3.82e-2)" "unprognostic (6.76e-2)" "unprognostic (4.12e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (9.55e-3)" "unprognostic (3.64e-2)" "unprognostic (1.12e-2)" "unprognostic (2.46e-1)" "unprognostic (8.09e-3)" "unprognostic (3.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.94e-2)" 21.7 20.8 14.1 20.4 15.0 31.9 17.1 14.7 17.0 13.1 15.7 22.2 34.5 12.9 26.6 23.8 12.7 16.7 28.4 15.4 16.3 34.5 22.4 15.8 26.3 15.6 14.0 11.0 24.1 23.7 14.3 23.2 16.2 21.6 23.3 22.3 18.7 14.5 39.3 15.8 31.6 15.5 14.0 21.7 23.9 12.5 15.0 19.2 18.0 35.4 23.4 18.5 15.7 15.7 56.8 28.6 27.8 37.4 34.5 55.4 75.7 65.7 32.0 41.9 35.9 47.0 27.7 57.6 48.4 42.0 51.4 28.0 34.3 31.1 50.2 57.8 28.5 38.0 32.8 59.9 52.9 70.2 57.3 45.5 48.0 54.9 72.5 41.3 52.9 41.1 66.6 84.7 64.1 18.6 36.4 54.3 42.7 40.0 54.8 25.7 49.6 25.5 51.7 45.5 22.2 27.6 42.3 60.5 93.3 43.3 13.2 88.5 45.7 39.2 27.5 62.0 80.1 48.7 51.9 46.3 82.5 60.0 23.7 11.8 10.9 9.4 11.8 14.4 15.5 10.6 11.1 14.2 9.6 9.0 10.2 11.6 5.3 13.5 26.1 9.3 24.7 9.3 14.1 15.0 14.7 17.0 15.4 16.3 15.6 14.0 16.2 14.0 15.0 15.7 20.5 6.4 16.2 15.0 27.1 13.6 13.7 23.2 17.6 24.2 19.8 14.0 52.8 11.5 20.4 18.4 12.5 56.7 30.9 30.5 25.4 42.1 19.3 23.0 17.2 20.7 19.2 25.0 20.7 34.5 85.9 18.8 18.8 24.0 13.3 19.8 21.0 17.4 80.9 21.9 22.2 26.2 20.3 48.8 14.5 9.0 19.3 29.5 16.0 21.5 46.2 25.5 25.7 21.1 33.5 57.3 31.9 12.8 36.0 16.1 79.4 73.9 21.0 29.7 6.6 14.3 20.2 43.0 23.2 21.7 14.6 46.4 32.1 25.7 33.0 20.2 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA036357: AB_10673128" "prognostic unfavorable (9.18e-6)" "unprognostic (5.87e-2)" "unprognostic (2.20e-3)" "unprognostic (2.88e-1)" "unprognostic (3.51e-2)" "unprognostic (3.71e-2)" "unprognostic (7.37e-3)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" "unprognostic (2.51e-2)" "unprognostic (1.72e-2)" "prognostic favorable (8.55e-6)" "unprognostic (1.62e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-1)" "unprognostic (5.76e-2)" 2.5 6.8 2.8 3.1 3.0 1.8 3.2 3.3 3.9 2.6 3.3 6.3 4.8 2.7 5.5 4.2 2.7 1.6 14.7 2.7 2.7 6.4 7.4 2.0 4.6 2.5 2.5 2.2 3.2 5.2 4.5 2.2 2.8 2.7 6.0 6.0 4.6 2.7 15.6 2.9 4.5 2.9 2.5 4.2 5.9 5.5 2.8 3.0 4.0 15.4 6.1 2.9 2.8 3.4 7.6 10.8 7.3 12.6 5.9 3.5 8.6 5.0 7.0 7.7 7.4 17.4 4.1 11.6 7.6 6.5 15.1 10.8 13.0 10.7 12.1 8.1 7.4 12.1 8.4 14.0 6.1 12.5 8.1 5.2 8.3 10.3 6.7 4.7 6.9 16.3 21.7 4.7 8.5 11.3 4.7 14.4 9.1 10.7 7.9 16.1 13.3 8.8 12.4 8.1 7.1 5.7 4.7 12.3 11.2 7.5 15.5 8.0 3.6 4.4 6.1 8.8 8.9 3.5 5.7 24.8 11.5 18.1 9.6 0.1 4.6 2.2 3.2 5.1 3.3 11.4 4.4 3.4 10.7 16.0 4.0 3.9 0.8 6.5 3.7 5.6 8.2 3.3 2.8 3.0 3.3 3.9 2.7 2.7 2.5 2.5 2.8 2.5 2.8 3.4 1.6 0.0 2.8 7.8 8.1 0.8 1.9 6.4 0.6 5.5 2.8 1.7 18.4 4.3 3.1 1.8 8.4 12.5 1.3 5.2 27.4 6.7 8.5 7.6 2.0 2.1 4.2 1.3 15.6 8.6 15.0 2.1 4.1 4.2 2.5 3.6 2.5 5.5 7.3 0.0 17.2 3.0 10.2 5.4 1.8 3.4 0.6 3.6 0.0 8.4 0.9 3.7 1.0 6.6 17.5 4.9 3.0 1.9 4.2 1.2 3.3 14.5 5.4 6.2 13.1 2.1 2.5 11.9 16.7 4.1 1.0 5.6 2.8 5.6 6.4 2.0 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA021565: AB_1856631, HPA021579: AB_1856632" "unprognostic (6.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.12e-3)" "unprognostic (1.09e-2)" "unprognostic (1.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.01e-2)" "unprognostic (3.02e-2)" "unprognostic (7.09e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-3)" "unprognostic (3.84e-2)" "prognostic favorable (9.69e-7)" "unprognostic (4.94e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.12e-2)" 16.4 18.5 9.2 12.2 9.4 8.9 14.2 9.7 9.5 12.5 14.5 18.8 19.9 13.6 8.0 16.5 10.6 8.0 24.2 9.2 10.1 20.0 30.1 10.2 12.0 9.7 9.4 10.4 9.6 15.7 12.5 11.3 9.7 12.8 14.6 9.2 11.9 9.7 24.9 12.1 16.8 9.2 9.6 12.0 13.2 12.0 10.0 9.6 13.1 17.2 9.9 13.5 12.3 10.2 32.6 46.9 19.0 25.5 22.8 19.4 40.7 35.2 18.3 31.1 29.9 24.0 18.5 56.8 37.4 31.6 19.1 35.0 38.0 33.4 34.7 30.1 48.4 29.3 28.8 34.0 32.5 20.5 20.8 24.7 21.4 29.3 46.3 16.2 22.5 36.9 30.3 9.8 32.4 18.4 28.7 21.1 42.0 36.6 23.9 33.8 23.6 25.4 40.3 23.2 10.1 29.2 41.6 25.4 37.2 24.4 32.1 14.4 26.9 23.7 20.2 25.6 37.1 15.5 16.5 21.6 19.3 25.5 26.3 6.6 15.5 14.8 11.5 18.5 12.2 13.2 10.0 12.0 15.2 9.8 12.2 12.8 5.1 11.1 20.5 10.9 14.3 12.2 9.2 9.4 9.7 9.5 9.2 10.1 9.7 9.4 9.7 9.6 10.0 10.2 18.1 22.4 19.8 5.9 24.3 11.5 23.3 32.2 13.1 20.4 14.0 13.2 39.5 18.6 23.4 18.4 66.7 61.0 15.5 34.6 41.1 26.1 4.0 13.7 25.2 19.1 15.7 22.1 4.2 20.4 102.6 19.7 24.5 15.9 8.8 22.4 19.6 38.2 29.8 16.8 4.7 25.3 26.4 18.9 9.5 5.4 18.6 15.9 10.6 6.5 28.4 20.7 22.6 2.5 5.4 24.1 19.3 19.2 18.4 33.1 31.6 49.8 16.1 37.7 6.6 23.8 19.1 28.4 37.0 21.5 11.8 60.5 17.5 43.0 35.6 23.0 SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA034689: AB_2674282, HPA034690: AB_10670574" "unprognostic (5.39e-3)" "unprognostic (4.58e-2)" "unprognostic (2.06e-2)" "unprognostic (3.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (5.85e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (6.62e-3)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" 16.4 16.4 11.8 9.9 14.4 5.2 13.5 14.7 16.0 9.5 7.0 12.9 18.5 11.9 11.4 16.2 10.4 11.2 26.0 10.8 13.6 20.2 22.0 12.2 11.4 14.6 13.4 13.2 14.7 27.7 14.0 13.1 13.6 15.2 13.2 22.8 11.0 12.5 40.5 13.8 14.3 14.0 12.9 11.8 12.4 10.6 14.1 12.4 20.3 35.8 12.1 10.4 8.3 18.5 15.9 9.7 25.8 22.8 18.8 21.1 13.7 24.1 19.0 18.2 22.0 9.6 11.4 3.0 15.6 24.2 14.0 15.5 19.3 21.1 23.9 34.8 17.8 29.7 21.1 7.5 27.8 22.8 15.0 23.5 25.4 34.4 24.5 20.4 21.8 16.7 20.2 11.1 25.0 18.0 18.9 22.2 12.0 35.4 41.0 9.3 25.7 17.5 21.2 16.5 16.0 44.5 16.6 16.2 30.7 26.4 21.8 21.7 15.7 20.9 10.9 25.6 21.0 29.4 32.8 0.5 22.9 11.2 21.8 7.2 5.2 2.2 4.8 3.3 3.4 8.6 5.1 4.6 5.1 11.0 7.8 6.3 20.0 6.9 4.3 8.0 5.6 2.6 11.8 14.4 14.7 16.0 10.8 13.6 14.6 13.4 13.6 12.9 14.1 18.5 7.8 9.6 15.6 18.6 7.0 3.6 12.1 23.7 12.5 12.8 7.9 6.3 22.8 4.3 12.5 9.2 10.4 10.7 3.8 8.4 13.7 9.1 5.1 9.4 8.3 6.0 6.0 11.6 21.0 9.8 6.3 6.9 11.2 5.4 8.8 9.5 8.6 8.7 9.3 18.5 26.3 7.3 20.3 5.8 2.2 4.0 4.7 6.2 3.6 6.5 6.1 22.6 7.2 27.6 25.7 12.2 4.0 6.8 10.3 5.4 9.9 12.5 13.6 15.0 0.0 8.2 7.1 18.9 7.1 20.4 4.8 6.8 5.8 13.0 6.4 9.7 SCYL3 "PACE-1, PACE1" ENSG00000000457 "SCY1 like pseudokinase 3" Q8IZE3 1 169849631-169894267 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005624 Approved Uncertain "Nuclear bodies,Microtubules" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" Microtubules "Nuclear bodies" "HPA005624: AB_1854916" "unprognostic (2.35e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.13e-2)" "unprognostic (2.72e-3)" "unprognostic (1.31e-1)" "unprognostic (2.12e-2)" "unprognostic (2.85e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.20e-3)" "unprognostic (3.54e-1)" "unprognostic (1.75e-1)" "unprognostic (4.60e-2)" "prognostic favorable (8.85e-4)" 5.6 5.8 2.7 7.4 3.0 4.0 10.9 4.0 3.5 6.7 5.0 7.8 7.7 7.0 8.3 7.3 6.3 7.6 5.2 3.0 3.0 7.5 11.3 6.2 10.5 2.9 2.8 7.6 6.1 12.0 4.1 8.1 3.1 7.6 9.6 11.4 8.2 6.7 7.9 7.7 6.8 6.2 2.9 7.5 7.7 6.6 3.0 9.7 7.6 9.1 9.8 7.3 6.5 3.9 4.1 5.2 7.9 5.5 9.9 7.2 9.1 6.3 8.1 7.2 6.7 4.8 7.7 8.4 4.5 6.5 4.0 9.4 4.7 5.5 6.4 15.5 4.4 5.8 6.1 3.1 7.0 8.5 7.3 7.0 5.4 5.0 6.8 6.7 6.9 9.2 9.4 10.8 6.9 3.2 6.9 6.5 6.4 27.5 2.5 6.3 4.3 10.1 7.6 7.3 5.9 8.6 5.0 16.3 10.1 11.2 9.1 7.8 5.2 5.1 3.4 6.2 5.1 14.4 13.7 9.9 3.9 6.3 5.7 13.5 3.2 8.6 6.3 3.4 8.5 6.7 8.3 7.0 5.1 6.2 7.0 5.8 6.7 10.7 3.8 11.5 8.1 4.8 2.7 3.0 4.0 3.5 3.0 3.0 2.9 2.8 3.1 2.9 3.0 3.9 5.9 6.4 14.4 11.8 9.6 2.4 2.5 3.6 6.2 10.2 9.6 8.3 4.2 22.8 7.8 1.8 10.4 17.6 19.0 14.0 9.8 7.4 5.1 11.1 8.2 6.6 9.1 4.2 15.8 9.1 5.1 5.1 7.1 5.8 5.7 7.2 11.0 13.2 6.5 10.1 12.5 10.4 8.2 11.4 3.5 2.6 4.4 5.3 1.8 9.4 8.4 10.0 16.5 17.6 14.1 6.2 10.2 5.7 10.5 4.7 13.3 6.4 9.0 19.9 6.6 5.5 5.4 10.9 6.8 8.3 1.8 11.6 11.0 6.3 10.3 3.3 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 70.6 148.0 60.5 29.6 62.7 38.4 65.8 78.7 71.3 50.2 63.2 131.9 148.9 53.2 27.3 67.1 50.3 33.9 601.0 60.8 73.4 139.1 276.8 54.3 43.1 74.1 62.7 65.8 71.5 122.9 44.8 28.8 75.7 46.3 82.1 42.7 66.8 35.6 479.0 58.9 116.8 36.1 61.7 66.4 115.6 56.4 71.7 41.8 49.6 224.8 36.5 63.2 56.3 63.7 88.4 154.2 54.8 95.0 96.9 68.5 154.1 63.3 81.8 107.2 108.4 163.9 115.9 108.3 218.6 70.2 92.1 111.8 102.4 129.7 66.3 241.9 98.9 50.1 390.8 224.1 60.0 69.5 70.7 70.6 84.3 83.6 33.7 93.6 123.9 83.5 84.6 83.1 48.7 155.8 93.9 206.9 19.3 101.4 193.5 119.0 84.6 223.2 245.4 122.7 62.3 35.4 332.5 205.5 90.7 36.1 115.0 93.2 91.1 80.3 82.1 48.2 52.5 93.0 40.9 79.8 81.6 99.9 52.5 66.6 70.8 88.1 95.2 85.7 86.8 79.5 92.5 94.5 93.3 73.3 89.2 85.0 14.1 85.5 74.7 59.5 149.3 111.3 60.5 62.7 78.7 71.3 60.8 73.4 74.1 62.7 75.7 61.7 71.7 63.7 29.4 35.3 71.1 20.2 50.9 61.2 81.4 105.8 31.3 51.0 24.6 17.0 272.6 64.3 78.5 75.4 102.2 109.6 39.3 169.7 142.8 94.7 58.7 39.1 30.1 39.1 47.5 56.8 34.4 44.9 102.8 49.4 47.9 48.5 43.7 64.8 47.5 167.0 67.5 101.0 39.9 96.3 105.8 41.0 55.0 28.8 68.3 38.8 90.7 12.2 60.2 50.7 52.5 19.1 37.9 54.2 100.1 55.7 67.5 37.0 274.4 190.7 75.2 87.2 78.9 33.2 51.7 96.9 54.3 40.9 35.9 154.7 56.7 85.0 160.1 88.2 SDHAF3 "ACN9, DC11, LYRM10, Sdh7" ENSG00000196636 "Succinate dehydrogenase complex assembly factor 3" Q9NRP4 7 97117698-97181763 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 148.7;Early spermatids: 136.0;Proximal tubular cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020515, HPA020523" Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020515: , HPA020523: AB_2670464" "unprognostic (3.94e-2)" "unprognostic (9.11e-2)" "unprognostic (6.51e-2)" "unprognostic (2.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.61e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-2)" "unprognostic (3.74e-2)" "unprognostic (3.07e-3)" "unprognostic (4.27e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-3)" "unprognostic (2.82e-1)" "unprognostic (3.79e-3)" "unprognostic (2.34e-1)" "unprognostic (8.45e-2)" 12.4 17.5 9.3 12.4 9.8 16.7 18.7 10.5 13.3 15.0 13.5 20.7 19.9 12.4 22.2 15.0 14.6 13.0 27.0 9.4 11.2 33.5 32.1 8.4 18.5 10.6 10.4 10.7 18.4 12.2 3.6 9.6 11.0 14.8 20.3 16.4 22.0 12.0 29.0 14.1 17.4 12.2 11.6 11.2 18.3 14.5 10.2 24.5 19.0 25.6 14.5 12.8 3.7 12.1 36.6 27.6 24.5 82.3 15.8 12.8 14.8 15.8 7.6 15.6 22.8 5.0 30.7 57.4 40.1 14.1 20.7 13.4 49.6 38.8 33.7 44.2 59.6 34.6 24.8 54.8 23.8 89.4 16.0 24.3 30.3 25.7 32.0 11.6 14.5 57.2 99.5 1.6 34.8 0.0 94.5 126.7 37.3 74.1 34.6 21.0 14.0 83.7 26.0 24.9 63.8 40.7 38.5 47.9 55.5 33.9 0.4 31.6 16.0 4.2 53.2 88.6 10.7 41.4 87.0 139.5 14.6 144.7 51.9 30.0 21.4 8.0 26.5 26.3 36.3 36.3 33.3 39.1 27.9 32.1 45.9 44.4 20.2 23.9 26.7 82.6 33.2 37.9 9.3 9.8 10.5 13.3 9.4 11.2 10.6 10.4 11.0 11.6 10.2 12.1 24.4 19.2 12.5 8.5 34.4 0.0 23.1 0.0 29.0 13.8 38.6 44.4 37.9 18.6 6.8 25.8 4.2 35.2 31.3 7.2 148.7 30.6 136.0 31.3 20.6 17.3 13.3 32.6 16.6 39.1 30.0 20.1 29.0 21.4 5.1 22.2 16.4 55.9 31.1 10.1 14.3 24.2 0.0 20.1 0.0 20.7 22.7 20.2 0.0 9.4 13.9 44.8 36.0 14.6 18.5 24.0 29.1 24.8 30.9 17.0 35.1 150.9 16.0 19.5 32.9 19.5 20.4 32.7 49.3 53.5 0.0 9.6 26.3 45.6 39.8 25.0 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 776.7;Proximal tubular cells: 916.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.48e-2)" "unprognostic (6.88e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-2)" "unprognostic (1.90e-2)" "unprognostic (5.02e-2)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" "unprognostic (7.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.20e-4)" "unprognostic (9.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.19e-3)" "unprognostic (3.77e-1)" 128.9 143.7 73.7 64.1 79.7 60.5 100.3 84.5 85.1 78.7 92.9 118.9 127.8 70.9 76.0 109.7 98.6 63.3 154.1 68.4 83.4 285.7 319.4 65.5 74.7 78.8 79.1 69.2 62.5 173.6 52.4 73.1 76.7 77.3 132.2 84.3 74.8 84.7 277.4 69.8 101.4 101.4 85.1 62.8 89.9 52.7 84.8 93.1 89.5 288.4 105.1 88.4 61.3 85.6 161.1 129.7 157.5 147.7 248.3 213.3 196.3 150.9 190.3 180.3 137.3 185.4 208.7 53.7 190.6 214.8 121.6 178.5 244.3 214.2 193.2 185.6 205.6 110.2 106.6 196.7 126.9 193.8 109.1 211.5 181.7 174.3 119.4 167.9 177.5 164.0 178.9 43.8 266.3 167.0 152.4 112.5 145.4 376.3 123.7 131.6 151.0 217.1 330.3 167.8 118.3 180.7 211.0 385.1 225.4 207.9 342.1 259.3 133.5 103.7 125.1 127.9 147.3 173.3 287.8 269.4 140.3 139.2 193.6 88.6 111.0 65.7 76.6 99.6 79.6 68.6 66.2 75.4 136.1 65.7 71.2 71.0 52.0 66.9 87.5 100.6 78.3 130.0 73.7 79.7 84.5 85.1 68.4 83.4 78.8 79.1 76.7 85.1 84.8 85.6 50.9 44.8 59.4 14.7 70.1 61.8 151.2 342.6 59.7 74.9 81.4 58.3 94.0 131.5 163.5 150.8 64.6 248.0 65.5 95.9 776.7 218.4 18.6 87.1 63.8 80.7 66.8 81.4 19.3 145.2 248.5 79.8 79.5 62.6 58.3 66.6 83.2 249.1 237.3 72.3 27.4 103.4 215.7 100.6 74.4 34.7 102.9 94.6 129.9 9.4 176.1 107.8 107.1 17.6 24.5 142.7 89.5 109.1 71.9 100.2 139.1 916.5 177.9 69.3 52.6 74.5 94.4 115.3 114.4 111.2 76.4 307.6 72.0 215.7 154.2 155.0 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SEC24C KIAA0079 ENSG00000176986 "SEC24 homolog C, COPII coat complex component" P53992 10 73744372-73772161 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040196, HPA040213" Supported Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040196: AB_10796449, HPA040213: AB_10796451" "unprognostic (5.06e-2)" "unprognostic (1.00e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-1)" "unprognostic (8.46e-2)" "unprognostic (7.23e-2)" "unprognostic (9.06e-2)" "unprognostic (4.55e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.71e-2)" "unprognostic (8.34e-3)" "unprognostic (2.11e-1)" "unprognostic (3.35e-2)" "unprognostic (1.77e-2)" 27.8 42.9 20.1 31.6 21.2 16.2 27.4 23.1 26.8 42.5 20.7 34.2 27.4 36.4 33.2 69.0 30.7 24.0 34.5 20.4 21.2 29.8 45.8 30.5 31.4 21.4 20.1 33.2 34.9 50.5 45.4 36.4 20.9 37.7 27.6 29.1 36.9 31.1 49.7 35.8 31.7 32.1 18.3 37.1 34.1 27.7 22.7 35.2 34.0 33.9 43.3 35.5 38.8 23.0 72.7 71.8 55.6 99.9 59.2 48.3 45.6 53.6 90.4 70.4 65.7 67.2 47.9 57.3 43.3 72.0 48.1 61.4 78.3 70.7 60.4 76.6 55.6 53.1 50.5 71.2 47.0 80.7 71.1 41.5 76.8 61.8 76.4 89.2 73.6 44.6 64.1 80.8 69.9 64.7 60.4 55.3 34.8 68.3 259.2 65.2 45.0 47.0 46.5 40.8 20.0 51.7 41.9 144.6 60.1 51.7 106.3 70.6 72.7 29.5 53.1 57.7 62.5 82.0 85.9 84.0 84.0 80.8 35.0 28.2 15.8 13.6 27.4 21.4 35.5 12.6 16.2 21.6 18.1 9.4 11.7 15.8 11.5 22.4 19.1 14.8 10.9 22.7 20.1 21.2 23.1 26.8 20.4 21.2 21.4 20.1 20.9 18.3 22.7 23.0 12.1 35.3 28.6 16.3 11.6 8.7 4.7 11.5 6.2 15.1 17.0 14.9 2.3 14.3 17.6 14.7 16.7 17.8 18.6 24.7 3.9 15.1 8.8 10.9 13.0 11.0 19.2 5.9 14.6 19.4 16.4 9.7 19.9 17.0 22.2 20.1 16.4 19.9 17.1 15.2 15.7 18.4 8.2 11.7 8.4 6.0 11.8 12.4 5.4 6.5 12.3 10.3 17.5 14.1 16.8 23.8 14.4 11.7 21.9 10.8 20.0 10.4 8.2 14.7 6.6 10.0 9.7 10.3 8.3 11.5 11.4 25.2 16.9 14.7 16.1 10.9 SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317428-13348298 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA037645: AB_10671631, HPA062118: AB_2732676" "unprognostic (8.18e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (2.07e-1)" "unprognostic (3.50e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.16e-7)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.61e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" 27.8 28.6 23.2 23.6 23.9 25.3 33.5 25.3 22.3 25.6 28.1 31.2 23.2 32.3 35.9 24.6 35.3 23.8 30.8 21.7 24.1 56.5 48.6 24.3 29.3 26.7 28.4 35.7 33.6 48.1 23.5 27.8 23.1 26.4 32.7 25.0 26.9 24.7 33.3 20.9 24.6 33.2 25.9 21.8 25.6 22.1 24.6 64.3 55.4 36.6 34.3 24.8 17.4 24.4 127.7 90.8 182.4 176.3 59.4 45.1 85.8 55.4 42.6 115.6 97.9 103.5 116.4 123.1 67.2 65.0 55.9 79.6 195.2 91.4 120.5 186.7 80.9 67.4 66.8 132.9 61.4 92.0 41.4 39.6 64.6 67.7 39.5 53.9 95.0 255.9 90.7 97.5 83.2 168.1 228.8 39.3 301.8 119.8 40.9 176.3 88.8 73.7 62.2 51.0 64.5 119.5 169.6 74.1 75.7 157.7 93.8 96.1 64.1 51.1 96.3 67.6 117.6 71.3 143.4 228.1 41.2 67.6 41.9 10.2 11.6 8.8 7.7 17.1 9.5 9.5 7.8 8.9 13.6 6.4 10.0 9.4 1.7 15.4 24.8 15.4 13.3 8.3 23.2 23.9 25.3 22.3 21.7 24.1 26.7 28.4 23.1 25.9 24.6 24.4 24.1 12.8 13.1 8.1 12.3 17.2 16.5 19.3 9.6 17.1 23.8 19.4 14.1 20.0 18.0 22.0 0.0 31.6 27.1 17.6 33.2 26.4 13.5 16.9 15.4 26.1 16.7 19.3 8.2 30.1 45.2 18.0 11.7 16.1 15.8 27.7 19.6 32.7 21.1 21.9 8.3 13.7 20.3 10.1 11.7 14.1 14.9 13.1 16.0 4.7 8.0 35.2 9.2 4.0 12.9 34.1 15.3 18.4 18.7 17.5 16.4 44.6 13.4 15.6 6.6 14.2 26.1 17.6 21.2 15.0 16.9 25.6 13.2 25.9 18.0 15.1 SERPINB6 "CAP, DFNB91, PI6, PTI" ENSG00000124570 "Serpin family B member 6" P35237 6 2948159-2972165 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 563.0;Late spermatids: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009668, HPA012736" Enhanced Approved Centrosome NA NA 4800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA009668: AB_1079919, HPA012736: AB_1856729" "unprognostic (3.44e-1)" "unprognostic (1.03e-1)" "unprognostic (8.72e-2)" "unprognostic (1.96e-3)" "unprognostic (2.72e-2)" "unprognostic (1.56e-2)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (7.63e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.51e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.59e-1)" "unprognostic (5.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.10e-2)" 122.7 170.7 101.1 66.9 108.4 66.6 107.9 103.6 134.3 135.9 103.8 133.7 191.2 95.9 82.2 131.5 118.9 77.7 243.9 98.6 104.2 136.7 63.3 151.7 52.7 111.7 107.1 169.7 282.5 94.4 92.0 133.5 110.6 160.4 103.3 56.4 92.5 95.6 232.0 50.9 210.3 89.4 105.8 164.5 115.0 203.8 106.7 26.7 101.3 266.8 47.2 107.7 95.5 115.4 156.2 99.6 32.2 134.3 85.6 189.2 99.2 142.1 170.7 109.9 127.3 35.0 108.5 0.8 161.6 161.7 124.8 228.8 90.3 144.1 102.2 204.9 41.2 90.7 111.8 60.0 148.5 1.1 53.0 109.4 98.5 104.8 26.9 191.1 263.7 0.5 118.7 2.0 198.0 110.7 0.5 1.5 19.1 175.5 188.8 10.1 59.3 130.7 138.7 37.1 1.5 82.5 116.9 17.3 162.4 118.6 75.3 73.8 188.7 111.1 41.4 252.0 97.1 3.0 0.6 2.7 85.4 90.8 117.8 60.6 104.9 121.2 51.5 107.6 25.7 27.3 28.9 35.5 103.6 22.9 33.7 56.1 8.6 86.0 90.7 10.3 5.0 91.1 101.1 108.4 103.6 134.3 98.6 104.2 111.7 107.1 110.6 105.8 106.7 115.4 127.8 51.3 69.6 34.3 33.0 20.5 68.4 141.8 23.9 28.4 62.4 63.0 142.6 42.9 141.6 75.4 20.9 146.4 56.8 237.9 99.7 194.6 563.0 89.4 91.4 137.5 73.0 29.9 14.2 338.3 346.6 84.9 108.6 47.8 104.5 83.5 232.7 31.9 182.3 30.3 21.5 169.7 114.0 181.9 70.2 1154.3 83.3 124.2 64.0 92.8 151.8 172.4 46.4 31.7 56.2 318.5 237.0 85.0 17.4 99.3 418.3 216.4 174.2 50.4 78.9 119.7 104.6 233.2 33.1 34.0 26.3 161.4 42.2 65.0 206.5 94.9 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIX4 AREC3 ENSG00000100625 "SIX homeobox 4" Q9UIU6 14 60709539-60724351 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 6.0;parathyroid gland: 15.1;salivary gland: 6.9;skeletal muscle: 14.4;tongue: 15.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Endometrial ciliated cells: 36.1;Glandular and luminal cells: 37.8;Prostatic glandular cells: 23.8;Respiratory ciliated cells: 30.3;Urothelial cells: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 32.1;hTERT-RPE1: 23.3;RH-30: 30.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA031794 Uncertain Approved Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA031794: AB_10602928" "unprognostic (2.23e-1)" "unprognostic (9.50e-2)" "unprognostic (2.63e-4)" "unprognostic (9.74e-2)" "unprognostic (2.69e-2)" "unprognostic (1.03e-1)" "unprognostic (5.39e-2)" "unprognostic (1.28e-2)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (4.39e-2)" "unprognostic (5.38e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (2.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.08e-1)" 0.7 0.7 1.0 0.2 0.8 0.1 1.6 2.0 2.6 2.2 6.0 0.3 0.1 0.9 0.7 0.2 2.4 0.6 0.5 1.0 1.6 0.8 0.1 0.7 0.0 2.4 1.6 1.4 1.5 15.1 2.7 0.9 2.3 2.6 0.0 0.3 6.9 0.6 14.4 0.1 0.1 0.4 1.2 0.0 1.5 0.3 1.4 1.3 1.0 15.7 0.1 1.1 0.4 1.5 32.1 2.1 1.9 7.9 7.2 8.7 14.5 7.1 10.5 2.0 3.0 1.5 10.2 0.0 4.6 3.5 2.0 11.8 8.4 5.8 4.7 2.6 6.4 0.9 3.2 2.1 2.3 3.4 0.3 4.2 2.7 1.7 9.5 23.3 1.8 0.6 6.6 0.0 10.6 7.6 0.0 0.3 5.3 0.2 13.2 2.1 30.2 0.0 3.8 17.3 5.0 0.5 4.3 6.7 1.9 2.8 9.7 0.2 6.4 6.3 14.0 4.2 6.3 2.2 0.1 0.0 2.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 2.0 2.6 1.0 1.6 2.4 1.6 2.3 1.2 1.4 1.5 0.1 3.2 0.5 0.0 0.1 0.4 13.9 6.9 6.8 0.5 11.9 9.7 3.3 0.0 8.3 1.8 20.9 5.0 0.3 0.1 0.0 0.2 0.1 36.1 2.9 0.9 1.8 0.0 2.6 1.1 4.1 3.2 0.0 37.8 1.3 0.1 0.4 0.3 0.3 0.0 3.2 0.0 2.0 0.0 0.3 0.0 0.3 0.7 1.8 0.0 0.0 1.6 0.0 4.0 0.1 2.9 0.0 1.5 1.3 23.8 0.0 0.3 30.3 0.4 0.0 9.7 2.5 0.4 1.3 2.2 0.6 3.1 0.9 0.1 0.0 17.2 SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 56.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 56.2" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 34.7;SiHa: 37.8" "Low region specificity" "Detected in some" HPA063062 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" 5.3 6.6 7.5 2.0 7.9 0.9 4.9 7.8 7.8 5.0 14.4 12.4 13.7 4.0 11.1 3.9 8.4 4.1 14.2 7.3 8.0 26.7 7.8 3.2 1.2 7.8 7.8 5.6 8.2 17.9 11.0 4.2 7.4 9.1 9.4 3.7 6.4 11.2 56.1 6.0 16.9 2.5 7.5 2.5 6.0 3.8 8.0 2.1 5.4 22.3 1.8 5.0 5.0 7.8 6.1 14.4 0.9 11.3 4.4 2.1 19.3 2.7 2.9 4.5 6.2 10.7 12.2 2.9 6.0 2.6 13.1 14.3 9.4 7.0 5.3 3.6 11.6 1.5 34.7 4.9 7.3 2.4 2.4 2.0 12.9 3.1 15.8 7.6 1.2 5.2 6.8 1.8 4.4 10.4 3.6 2.4 1.0 10.5 6.2 1.3 0.0 15.9 13.5 15.2 4.8 3.3 37.8 28.9 7.6 2.9 13.5 3.1 0.7 0.7 3.9 9.5 3.3 6.0 12.8 0.1 2.9 5.9 2.7 0.0 2.0 0.0 1.1 1.0 1.2 0.6 1.1 1.4 3.1 0.6 1.1 1.4 0.2 0.8 0.3 0.2 2.1 1.0 7.5 7.9 7.8 7.8 7.3 8.0 7.8 7.8 7.4 7.5 8.0 7.8 3.0 9.6 8.2 23.5 3.8 7.6 7.5 4.7 13.1 6.7 16.9 5.3 5.6 21.5 5.5 16.5 12.5 23.6 3.2 63.9 1.9 9.8 2.0 13.7 10.3 2.6 7.2 1.7 11.9 5.2 5.5 5.6 16.3 26.6 0.0 6.1 2.9 8.6 4.2 10.1 11.1 14.3 8.2 6.7 1.6 2.8 6.5 5.9 5.4 17.8 1.3 9.4 0.0 7.1 4.2 6.4 26.3 4.1 4.8 14.2 56.2 22.2 9.4 7.1 0.0 17.7 3.8 8.4 2.8 9.6 6.3 8.2 4.0 0.3 18.0 9.0 SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Hepatocytes: 64.2;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 96.1;RPMI-8226: 138.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" 20.7 29.9 16.3 11.9 18.2 10.7 17.9 18.6 16.4 8.3 15.3 26.5 65.6 10.4 4.6 9.1 12.8 15.7 62.8 15.5 17.9 25.6 148.3 15.6 14.6 17.7 17.4 5.9 30.4 17.3 11.6 7.3 17.8 11.7 23.5 4.5 19.9 9.0 66.5 10.4 52.7 15.1 17.4 20.6 21.0 9.1 17.5 17.3 11.4 61.1 16.1 11.3 8.4 18.4 4.1 12.8 9.7 13.8 30.1 11.8 1.9 22.3 11.8 15.2 15.8 16.3 19.1 19.0 15.6 35.1 18.7 4.1 24.5 9.8 11.6 47.9 11.8 26.4 19.2 20.4 14.0 27.8 48.1 14.9 11.2 20.6 3.8 6.1 20.2 28.1 24.1 96.1 20.2 10.9 30.4 13.7 5.1 22.9 27.6 10.6 5.9 138.4 16.4 10.1 3.9 13.6 20.7 0.2 11.4 13.6 30.5 12.9 16.6 17.2 3.2 25.5 16.4 35.6 27.0 21.8 24.5 19.5 23.3 60.8 101.1 215.2 97.4 79.7 62.2 36.8 53.1 71.2 97.5 33.0 41.2 69.1 48.6 64.6 83.7 120.5 60.7 112.3 16.3 18.2 18.6 16.4 15.5 17.9 17.7 17.4 17.8 17.4 17.5 18.4 7.5 6.4 2.7 13.1 7.0 1.8 2.5 4.6 3.4 1.1 4.0 3.6 42.2 4.3 4.4 0.0 6.2 2.3 13.6 28.4 3.9 3.5 1.3 2.3 4.6 5.5 7.3 16.4 2.2 4.3 2.3 6.1 9.2 2.1 1.3 3.8 7.5 64.2 16.9 0.0 3.8 12.7 2.0 13.4 4.5 1.8 10.5 10.0 1.8 1.0 31.3 2.9 32.0 1.0 6.0 3.7 16.4 12.4 12.6 3.9 51.8 16.7 5.9 1.3 0.0 5.4 5.3 8.3 7.1 4.1 1.3 1.2 14.4 27.7 16.6 2.9 SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1537.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1748.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 83000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045709: AB_10965843" "unprognostic (1.16e-2)" "unprognostic (4.68e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-2)" "unprognostic (6.38e-2)" "unprognostic (3.25e-3)" "unprognostic (9.41e-2)" "unprognostic (4.98e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "prognostic favorable (8.11e-7)" "unprognostic (3.45e-1)" "unprognostic (2.99e-1)" "unprognostic (8.66e-3)" "unprognostic (4.72e-2)" 300.9 550.7 131.2 184.7 136.0 209.2 267.5 159.3 146.5 224.3 209.3 418.9 396.4 283.5 226.1 437.7 248.9 136.2 1237.8 132.6 160.4 419.8 370.1 255.7 201.7 148.9 149.6 290.2 392.2 499.7 216.9 192.4 153.0 209.9 347.6 167.2 302.7 220.9 1537.4 275.7 321.2 257.4 150.4 235.1 423.5 90.8 159.0 205.7 225.1 1233.2 312.8 294.7 264.6 135.4 731.4 447.1 620.0 509.6 534.1 891.5 1005.3 622.8 724.1 704.3 573.4 787.6 316.4 1003.2 376.9 633.0 320.3 573.7 616.9 741.3 680.6 402.9 651.8 589.5 297.4 563.3 683.0 665.7 416.6 857.3 616.8 494.2 681.2 994.3 990.8 488.8 654.9 240.5 782.7 436.5 642.5 724.2 605.4 540.6 988.5 703.0 730.3 1075.0 858.8 559.6 355.5 506.1 740.1 565.5 1009.8 504.4 771.0 676.3 782.0 371.2 390.0 442.8 603.4 486.5 648.5 678.1 295.6 368.3 494.9 184.7 408.9 223.2 244.7 520.2 285.6 298.5 270.8 271.4 534.7 222.6 281.3 269.8 166.6 288.5 545.2 321.7 377.4 637.0 131.2 136.0 159.3 146.5 132.6 160.4 148.9 149.6 153.0 150.4 159.0 135.4 319.2 214.7 294.8 46.0 392.2 376.0 590.6 751.4 495.1 223.1 442.5 549.3 1748.6 370.3 384.5 215.2 79.2 785.9 480.8 727.5 874.6 512.1 41.7 217.9 275.3 328.6 312.4 413.5 44.9 879.5 946.2 393.1 390.4 288.7 210.4 477.9 278.1 416.3 589.4 292.7 49.7 470.7 370.2 467.9 280.7 29.0 255.1 449.1 437.6 34.7 593.5 317.3 294.5 32.2 42.2 632.9 602.7 256.5 442.7 652.4 945.5 1029.4 201.1 230.2 302.4 470.5 733.5 126.1 169.9 796.6 362.4 814.7 356.3 536.0 729.1 769.9 SLC25A30 ENSG00000174032 "Solute carrier family 25 member 30" Q5SVS4 13 45393316-45418455 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 71.6;skeletal muscle: 86.3;tongue: 63.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 38.8;Hepatocytes: 43.6;Proximal tubular cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045260 Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA045260: AB_10962505" "unprognostic (9.23e-2)" "unprognostic (9.92e-2)" "unprognostic (1.05e-1)" "unprognostic (4.28e-2)" "unprognostic (1.96e-1)" "unprognostic (2.63e-1)" "unprognostic (1.35e-2)" "unprognostic (3.16e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (5.69e-2)" "unprognostic (1.58e-1)" "prognostic favorable (9.91e-8)" "unprognostic (2.24e-1)" "unprognostic (5.19e-2)" "unprognostic (4.12e-1)" "unprognostic (6.19e-3)" 9.5 9.9 5.2 6.0 6.2 10.5 8.4 5.1 6.0 9.7 8.6 5.6 4.3 9.1 6.8 7.0 6.5 7.5 71.6 4.7 6.5 41.9 32.2 7.7 8.3 5.6 5.4 18.5 5.5 5.1 4.3 4.3 6.0 13.6 6.0 1.6 8.2 12.7 86.3 5.9 4.4 10.1 5.3 11.5 5.1 6.1 5.6 5.1 11.4 63.3 7.9 6.3 6.2 5.4 3.9 8.4 5.0 21.4 24.4 15.5 1.7 18.2 10.5 15.3 9.2 8.8 10.4 0.0 15.5 18.6 11.4 7.4 11.6 18.2 18.1 12.8 9.4 14.6 5.5 23.8 14.4 20.9 18.9 10.1 12.1 22.6 16.7 18.0 26.9 14.3 8.9 0.0 31.3 4.6 7.7 14.6 7.3 4.5 10.7 19.1 8.3 7.8 33.3 3.2 1.0 5.0 10.2 16.1 14.7 8.6 12.0 28.0 10.0 14.2 8.0 16.0 12.6 3.7 8.0 0.3 15.6 19.5 22.3 0.0 1.2 1.9 0.8 1.3 0.6 0.6 0.9 0.9 1.7 0.6 1.0 0.4 0.0 0.7 0.6 2.2 0.3 0.5 5.2 6.2 5.1 6.0 4.7 6.5 5.6 5.4 6.0 5.3 5.6 5.4 6.2 6.4 2.2 4.2 4.5 12.9 2.0 4.2 1.2 1.9 8.6 4.4 38.8 8.6 2.5 14.7 4.2 0.8 5.6 1.6 23.5 3.2 10.1 7.4 3.5 6.0 2.4 3.0 3.6 1.4 0.9 2.6 1.1 7.8 5.1 7.7 9.3 43.6 4.1 0.0 4.2 3.4 6.1 10.0 7.7 7.7 5.0 6.5 5.4 5.6 6.6 0.9 3.1 4.0 0.8 2.2 1.6 6.4 3.9 3.9 2.1 29.5 3.4 1.0 6.6 3.6 3.3 0.3 1.8 3.8 6.1 0.5 6.6 8.6 3.3 1.5 SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 238.9;Late spermatids: 448.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA039601: AB_2676592, HPA071582: AB_2686422" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "prognostic favorable (8.41e-4)" "unprognostic (4.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.98e-1)" 22.9 15.9 10.4 19.9 11.8 17.6 16.4 12.7 16.7 18.5 7.8 22.1 23.8 14.7 10.5 21.2 10.7 15.8 31.1 12.2 12.2 29.7 30.0 16.7 22.5 12.4 10.2 11.7 15.4 20.6 4.9 17.0 13.2 15.7 21.6 18.8 13.3 16.0 55.8 14.9 20.9 20.8 10.3 15.7 20.1 21.9 11.2 24.8 19.8 60.2 26.8 19.0 6.6 14.1 36.2 27.7 25.7 20.7 65.2 60.2 9.9 44.3 55.9 47.5 59.3 37.6 28.7 96.8 44.8 50.1 61.9 29.6 41.0 71.2 54.3 61.8 20.8 40.1 35.2 25.6 53.1 37.3 40.2 49.9 25.4 55.5 39.6 29.5 31.9 37.2 31.4 56.4 54.1 27.3 54.0 17.2 18.1 25.7 24.7 26.0 57.0 71.5 35.1 39.2 46.7 33.5 37.7 29.7 49.7 23.7 30.9 35.3 42.5 43.6 21.0 40.7 54.4 111.8 76.2 68.4 48.0 43.8 24.0 29.2 16.0 13.2 12.3 19.0 12.5 14.4 13.7 12.9 17.0 14.5 14.5 14.8 6.6 20.9 17.7 11.1 18.2 17.4 10.4 11.8 12.7 16.7 12.2 12.2 12.4 10.2 13.2 10.3 11.2 14.1 21.3 22.4 24.8 40.8 26.7 22.9 9.1 16.0 31.9 16.8 15.7 10.8 63.5 11.5 12.9 20.2 22.9 21.7 18.0 34.8 19.6 18.1 238.9 10.4 20.1 18.9 23.4 29.9 73.3 25.6 18.2 22.6 34.7 12.1 19.0 16.2 26.7 43.9 27.2 18.5 63.9 28.3 32.6 26.1 21.0 448.2 21.1 23.9 30.2 31.9 28.1 21.9 17.5 49.8 91.8 18.9 22.8 22.2 73.8 8.0 26.5 41.7 14.9 14.1 19.7 18.5 22.6 23.3 14.2 30.0 26.9 20.5 23.9 22.7 24.0 6.8 SLC35B1 UGTREL1 ENSG00000121073 "Solute carrier family 35 member B1" P78383 17 49700934-49709014 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048655, HPA057418" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA048655: AB_2680481, HPA057418: AB_2683432" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (1.09e-3)" "unprognostic (6.36e-2)" "unprognostic (8.31e-2)" "unprognostic (2.86e-3)" "unprognostic (6.17e-3)" "unprognostic (4.39e-2)" "unprognostic (2.47e-2)" "unprognostic (4.00e-3)" "unprognostic (3.37e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (5.69e-7)" "unprognostic (6.28e-2)" "unprognostic (7.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-2)" 13.4 9.9 16.8 15.6 17.1 19.4 18.6 17.3 20.0 16.7 21.7 19.9 26.8 11.4 52.8 17.2 18.1 12.5 32.2 17.1 20.0 28.8 46.4 15.3 14.3 17.4 17.8 8.5 18.4 31.6 13.7 17.0 17.4 13.7 24.2 17.0 16.4 15.5 61.4 10.8 26.0 15.6 16.5 12.4 17.4 14.0 18.4 15.3 36.0 60.3 21.6 23.0 7.9 17.2 45.2 75.5 52.4 87.7 47.5 32.9 59.7 46.4 77.8 98.7 80.5 156.6 52.3 31.5 104.7 66.7 55.0 32.6 87.1 55.3 103.5 38.3 65.3 38.5 43.8 94.0 85.3 71.9 34.9 31.9 60.3 73.1 83.6 24.6 64.7 46.5 40.0 84.2 68.1 94.2 51.9 52.5 23.6 82.4 92.2 37.4 56.6 85.6 47.1 45.5 45.8 60.4 25.9 21.3 34.0 57.7 68.7 50.0 26.6 74.0 33.3 84.0 61.9 48.3 79.6 42.7 50.2 54.6 63.8 25.1 27.2 10.1 15.8 27.7 12.0 11.6 10.9 15.4 32.1 6.8 11.2 10.0 11.2 13.5 19.3 43.3 13.6 16.1 16.8 17.1 17.3 20.0 17.1 20.0 17.4 17.8 17.4 16.5 18.4 17.2 32.1 16.0 29.7 10.7 37.1 22.3 40.0 56.4 22.8 28.2 37.1 29.0 40.5 21.5 45.3 27.6 35.5 57.8 47.4 34.9 35.2 78.4 52.4 19.1 25.1 39.2 50.6 20.4 11.7 101.7 121.0 28.6 16.3 24.1 42.5 22.8 27.8 56.6 73.5 21.9 10.4 56.2 59.0 28.0 45.2 17.6 30.1 34.0 37.4 4.7 39.6 44.6 26.8 11.6 11.2 77.5 33.2 20.7 103.7 70.1 139.9 51.3 33.9 35.4 13.1 25.3 47.9 63.2 41.2 24.5 25.1 80.4 31.1 24.1 41.7 50.6 SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 67.6;skeletal muscle: 80.2;tongue: 29.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 53.0" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.8 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.2 0.1 0.0 67.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 80.2 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 29.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.4 0.2 0.2 1.1 0.4 0.1 0.4 0.1 0.1 0.2 0.1 0.8 0.6 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.9 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 SNF8 "Dot3, EAP30, VPS22" ENSG00000159210 "SNF8 subunit of ESCRT-II" Q96H20 17 48929316-48944842 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 341.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059320 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA059320: AB_2683977" "unprognostic (7.85e-3)" "unprognostic (3.97e-3)" "unprognostic (2.25e-2)" "unprognostic (1.73e-1)" "unprognostic (4.39e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.52e-1)" "unprognostic (1.38e-1)" 28.7 31.7 24.6 26.0 26.9 35.2 26.6 25.8 27.1 21.5 24.7 28.4 27.6 21.3 32.1 26.9 20.3 20.5 42.7 23.9 25.7 33.0 33.1 21.9 24.8 25.9 25.9 18.5 29.7 26.1 18.3 22.0 26.1 20.1 30.7 18.1 29.6 21.5 48.6 23.7 24.4 25.8 25.6 22.7 30.0 18.4 25.5 27.8 25.5 48.5 32.5 26.7 20.5 29.2 60.9 119.3 73.2 93.3 73.7 42.4 114.0 49.9 68.1 95.0 84.8 294.6 61.5 55.3 85.5 94.3 106.0 39.8 68.0 70.1 105.4 80.1 110.7 61.6 158.7 126.1 64.2 83.8 66.6 52.7 68.9 91.0 69.2 70.5 90.4 71.7 61.4 54.7 98.2 120.7 90.8 71.4 35.6 139.1 101.3 58.9 132.8 65.8 57.1 67.4 48.0 96.3 60.1 28.1 73.5 125.2 70.9 101.3 77.2 103.6 81.1 65.3 95.1 79.6 97.5 66.0 92.1 45.1 81.5 0.9 4.4 9.2 2.5 5.0 1.3 4.4 3.5 2.8 5.0 5.4 2.3 1.9 1.9 1.6 5.7 6.2 4.7 1.1 24.6 26.9 25.8 27.1 23.9 25.7 25.9 25.9 26.1 25.6 25.5 29.2 77.4 44.8 34.4 14.7 60.0 59.8 76.5 46.4 26.2 67.9 75.0 80.9 49.0 68.6 34.4 64.4 14.6 119.6 71.3 126.4 148.7 147.8 111.9 48.3 57.6 63.5 70.8 71.8 21.4 218.4 175.7 62.8 52.5 41.7 43.1 87.5 61.8 75.2 149.1 25.2 22.7 93.2 48.8 84.4 96.2 341.1 62.7 82.7 85.4 8.4 137.9 95.1 80.3 12.1 17.6 166.6 78.7 62.1 88.6 100.0 125.4 210.1 33.7 86.7 46.0 51.9 123.3 68.0 76.3 58.6 72.5 95.1 57.7 75.0 98.9 95.9 SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: AB_1080042" "unprognostic (3.30e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (4.44e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.52e-2)" "unprognostic (3.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" 30.5 31.1 24.7 35.2 25.7 39.2 37.5 29.6 34.8 31.8 25.7 50.5 33.2 35.5 35.5 43.5 36.7 20.2 35.3 25.0 25.8 48.0 64.9 26.9 47.7 23.7 23.9 34.3 23.7 51.2 27.0 24.7 25.5 33.8 40.7 54.1 29.7 31.9 103.7 28.8 35.7 29.5 23.6 34.3 36.5 24.7 25.0 74.4 38.9 86.2 53.3 39.5 32.3 30.7 182.5 45.7 188.6 58.5 70.1 57.7 56.1 173.1 74.8 166.1 148.1 61.4 65.8 158.7 70.1 109.2 83.0 130.7 252.1 219.3 175.5 107.9 188.8 152.4 95.4 113.9 66.2 408.0 95.7 66.5 93.8 186.3 86.6 81.8 120.6 139.8 116.2 60.5 61.5 56.8 187.0 82.6 98.9 237.8 61.9 179.5 190.7 66.6 154.5 130.0 82.2 95.6 83.4 62.7 87.7 162.7 102.3 97.5 135.5 127.0 126.3 74.3 126.2 74.3 168.2 283.7 70.1 127.1 91.4 18.5 42.9 53.9 35.6 50.2 37.6 60.5 38.4 39.2 54.2 50.7 36.6 41.3 18.6 51.1 51.1 49.7 41.1 47.4 24.7 25.7 29.6 34.8 25.0 25.8 23.7 23.9 25.5 23.6 25.0 30.7 120.0 96.1 81.8 7.5 118.2 108.6 115.3 293.1 133.1 61.1 94.2 138.8 95.9 101.5 162.9 130.6 35.5 239.5 123.1 112.6 291.6 161.9 91.0 176.6 157.7 96.8 111.0 139.4 8.1 114.8 228.8 121.0 92.2 147.9 86.2 145.3 66.0 203.3 176.4 38.7 8.7 134.2 168.9 74.5 84.8 85.1 116.2 98.1 67.6 10.3 151.0 134.3 86.5 8.0 13.4 129.4 118.2 118.5 120.7 96.8 191.7 310.5 135.2 68.9 65.7 102.8 209.6 111.1 131.4 164.9 113.7 180.3 111.9 176.2 139.0 113.3 SNX12 ENSG00000147164 "Sorting nexin 12" Q9UMY4 X 71056332-71073426 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070423 Approved NA NA 89000 "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB070423: AB_11153407" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.83e-3)" "unprognostic (9.88e-3)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" "unprognostic (9.55e-2)" "unprognostic (1.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (1.51e-7)" "unprognostic (3.52e-2)" "unprognostic (8.81e-2)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" 26.6 37.6 36.4 27.4 38.3 28.1 29.6 34.4 39.9 31.9 26.0 35.9 37.4 36.1 34.2 49.7 33.2 30.0 40.7 33.7 40.2 42.1 25.0 26.9 23.4 36.8 38.7 39.2 24.8 59.6 18.8 35.6 37.2 33.7 34.3 28.5 27.9 43.9 44.3 43.3 42.8 41.0 37.4 24.1 32.6 16.1 40.6 25.2 42.0 51.3 29.3 40.4 31.2 34.4 67.9 97.6 53.6 46.8 79.9 73.2 58.7 75.8 75.7 74.1 65.7 73.2 110.7 36.4 62.9 89.7 120.3 57.4 104.8 89.4 64.3 29.0 55.4 39.3 108.8 40.7 65.4 38.4 46.0 57.9 94.3 94.5 67.5 61.3 87.1 37.6 60.8 61.3 108.6 69.7 46.5 28.9 71.6 109.7 84.6 45.2 81.6 57.2 60.5 58.3 36.9 28.4 101.4 55.9 65.1 65.2 35.5 30.1 101.5 66.8 64.8 92.6 46.0 35.0 54.8 42.7 64.8 83.9 47.8 6.9 2.9 4.9 2.6 4.2 3.0 4.2 2.9 2.3 3.3 3.1 2.2 3.5 2.5 3.5 2.5 2.7 4.7 1.6 36.4 38.3 34.4 39.9 33.7 40.2 36.8 38.7 37.2 37.4 40.6 34.4 12.2 0.0 6.7 2.9 11.8 15.3 22.5 17.2 22.2 10.1 15.4 13.5 21.4 21.5 12.8 11.0 2.1 40.2 5.6 21.8 11.7 27.3 0.5 3.6 11.8 16.8 10.8 10.1 6.4 24.4 22.5 13.5 10.7 8.2 14.5 6.6 16.8 13.8 24.3 15.2 6.0 16.8 16.2 17.6 11.2 1.2 10.8 12.8 17.8 1.9 24.1 12.5 15.5 7.1 4.8 31.5 9.0 19.9 5.9 12.3 48.1 29.7 3.4 10.2 26.3 8.7 14.8 5.9 14.7 22.2 16.3 33.1 10.1 25.8 16.5 18.0 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SP2 KIAA0048 ENSG00000167182 "Sp2 transcription factor" Q02086 17 47896150-47928957 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003357, CAB010245" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "CAB010245: AB_2121523, HPA003357: AB_1080070" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (6.30e-3)" "unprognostic (5.85e-2)" "unprognostic (1.18e-1)" "unprognostic (6.91e-2)" "unprognostic (5.66e-2)" "unprognostic (2.46e-1)" "unprognostic (6.46e-2)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (5.39e-2)" "prognostic favorable (1.82e-5)" "unprognostic (5.34e-3)" "unprognostic (4.28e-2)" "unprognostic (3.37e-2)" "unprognostic (8.66e-2)" 14.8 10.7 9.4 16.6 11.6 19.4 15.4 16.1 11.5 12.9 6.9 14.3 14.9 14.7 12.0 17.2 15.1 11.5 18.3 9.6 10.1 12.5 8.7 14.9 20.6 12.4 10.4 15.1 16.0 23.5 9.8 13.6 11.1 13.5 13.3 10.5 16.2 12.5 32.2 14.8 15.6 12.8 8.3 17.7 13.0 17.8 11.8 25.3 18.1 26.6 15.0 13.6 13.4 13.3 33.5 37.3 25.1 21.6 12.1 11.2 26.1 19.3 13.6 19.0 17.1 41.3 16.2 28.6 17.4 24.7 20.1 25.6 17.5 16.4 19.9 41.7 26.6 28.5 25.6 22.3 11.2 26.4 34.2 16.4 19.1 22.4 21.1 13.5 18.5 26.3 31.8 47.5 18.8 45.0 64.6 16.8 11.8 29.6 24.9 30.8 34.4 18.6 13.4 52.1 26.8 31.4 16.9 17.9 20.0 15.0 26.7 25.6 30.3 34.8 18.1 24.2 30.1 42.3 50.6 26.0 19.0 18.5 29.2 13.6 6.1 9.9 8.3 7.0 7.3 4.9 6.3 7.9 4.9 5.6 7.1 7.4 11.3 9.7 6.6 4.5 7.2 6.6 9.4 11.6 16.1 11.5 9.6 10.1 12.4 10.4 11.1 8.3 11.8 13.3 14.6 9.6 19.5 5.2 17.7 6.2 15.8 7.8 12.0 9.0 9.8 9.9 9.7 12.8 8.3 11.0 0.0 10.7 11.3 16.4 15.6 7.0 9.8 8.1 6.2 11.6 15.6 25.2 5.2 7.6 9.2 9.4 8.6 10.7 13.3 5.5 8.2 7.5 8.9 11.8 4.8 9.0 14.2 10.9 8.2 10.5 10.5 14.2 8.8 6.5 11.7 12.1 17.5 9.0 9.9 7.3 13.2 3.4 12.7 11.0 8.6 8.1 10.2 6.5 6.6 12.6 12.5 9.8 6.3 9.6 7.5 20.5 14.8 5.3 7.9 17.0 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765709 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 41.1 34.7 8.3 57.6 10.9 54.5 32.0 11.1 8.5 36.6 48.6 93.4 79.6 27.9 21.5 26.5 26.8 39.4 37.1 6.8 12.3 57.9 107.0 43.4 40.2 15.3 12.8 13.6 63.7 158.5 13.0 54.1 12.5 29.5 82.8 12.5 44.5 32.6 109.3 25.2 67.6 41.0 11.2 37.3 41.7 18.5 12.1 39.5 35.2 81.8 41.7 51.7 20.9 14.5 57.3 96.9 37.0 49.2 142.3 84.3 58.2 89.1 149.1 80.5 114.1 113.1 64.3 35.1 65.0 176.3 120.7 83.5 45.2 54.3 89.5 72.2 27.5 67.0 61.5 58.9 117.4 42.0 104.5 73.9 98.3 66.8 106.7 59.4 80.2 37.7 51.3 134.2 107.6 131.5 20.1 16.2 15.8 90.8 22.0 24.2 57.3 77.6 109.7 130.4 29.7 33.4 54.0 102.7 63.4 74.0 73.2 81.6 98.9 128.7 51.7 83.7 106.7 54.0 100.2 38.8 58.1 69.4 90.3 48.7 52.3 48.9 27.9 48.6 17.4 18.3 22.3 25.5 37.4 19.2 12.4 20.5 37.7 23.5 56.6 33.1 30.4 50.2 8.3 10.9 11.1 8.5 6.8 12.3 15.3 12.8 12.5 11.2 12.1 14.5 66.2 48.1 35.9 20.5 51.9 43.1 79.1 76.3 37.5 14.8 36.4 21.3 77.5 52.9 44.3 68.0 20.9 136.5 72.7 215.5 23.5 87.1 18.8 107.2 56.6 59.6 38.4 30.3 32.0 167.1 88.3 74.3 52.0 57.3 45.7 20.5 46.8 124.1 85.9 8.4 31.4 86.5 36.7 68.7 55.7 7.0 44.7 83.0 32.0 23.4 134.5 27.5 64.9 25.6 26.2 131.9 127.3 36.5 49.9 92.2 143.0 46.8 41.8 17.2 26.3 88.0 51.6 31.7 15.3 39.3 38.8 204.5 60.6 30.8 76.0 94.1 ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 75.9;PC-3: 131.8;RT4: 102.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040466 Approved "Intracellular and membrane" NA NA 860000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" 25.7 22.5 8.8 22.8 8.6 22.6 12.2 5.3 9.4 11.4 12.3 6.5 3.6 11.6 12.7 14.0 15.5 19.0 53.1 9.6 6.3 44.5 67.7 19.2 23.1 7.9 11.2 13.3 15.4 10.9 9.9 13.8 6.9 8.0 5.5 10.0 24.9 10.2 43.8 5.9 9.9 10.6 7.2 21.2 16.1 4.3 7.4 17.4 66.1 49.3 21.6 34.4 10.9 7.2 14.0 6.6 3.0 8.3 28.6 15.0 14.4 15.4 35.5 5.7 4.4 13.3 15.1 3.3 10.3 28.2 2.7 4.2 9.4 11.3 4.9 37.6 1.7 28.4 22.5 25.4 22.0 5.9 22.1 17.8 5.7 19.5 11.7 27.2 26.4 7.5 0.5 42.5 4.4 14.9 8.4 8.0 2.1 75.9 131.8 9.9 3.7 24.3 2.7 102.2 0.7 2.0 6.8 23.3 6.9 15.4 4.3 8.1 26.3 18.3 28.5 15.7 6.9 53.0 39.3 3.6 41.7 19.8 18.5 47.8 8.8 41.7 24.1 8.1 22.9 22.7 25.2 28.3 5.3 38.6 34.4 32.4 16.1 43.2 20.4 12.6 17.2 18.9 8.8 8.6 5.3 9.4 9.6 6.3 7.9 11.2 6.9 7.2 7.4 7.2 29.4 6.4 56.8 38.2 68.4 5.7 14.4 14.8 21.1 13.4 13.7 8.4 63.2 12.8 22.2 1.8 2.1 9.7 65.5 4.6 5.9 41.3 3.4 8.9 29.2 44.3 0.0 38.5 36.7 25.4 53.5 47.8 10.7 28.1 8.8 12.1 37.9 159.8 37.8 60.6 34.6 0.6 16.2 52.5 29.0 2.1 36.7 48.8 14.2 49.6 59.8 11.5 47.4 5.0 2.4 39.4 0.0 71.8 29.1 10.9 0.0 48.5 6.5 23.3 13.1 28.1 23.6 0.2 2.8 30.0 3.4 26.4 79.9 6.5 0.3 43.6 STN1 "bA541N10.2, FLJ22559, OBFC1" ENSG00000107960 "STN1 subunit of CST complex" Q9H668 10 103877569-103918184 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.4;Distal tubular cells: 41.1;Ductal cells: 34.6;Exocrine glandular cells: 79.2;Pancreatic endocrine cells: 62.9;Theca cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037924, HPA037925" Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA037924: AB_10671636, HPA037925: AB_10672469" "unprognostic (1.50e-1)" "unprognostic (4.22e-2)" "unprognostic (2.18e-2)" "unprognostic (5.58e-3)" "unprognostic (6.01e-2)" "unprognostic (1.53e-2)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (5.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "unprognostic (3.76e-1)" "prognostic favorable (1.12e-6)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.83e-2)" 15.7 22.2 8.8 12.2 10.1 13.5 17.1 11.3 9.4 13.3 11.5 14.5 12.0 12.0 9.8 41.0 12.2 18.3 35.0 8.2 11.1 17.9 13.1 25.2 16.0 13.1 11.0 22.2 20.9 33.6 14.9 17.1 11.5 10.2 16.4 6.4 18.7 13.3 22.4 13.3 11.0 15.4 9.9 15.3 22.2 23.4 11.5 24.5 17.6 28.9 22.8 22.5 18.5 11.2 26.8 19.7 23.8 19.6 18.6 57.6 7.6 12.6 36.5 16.4 14.6 11.4 43.6 16.7 22.2 16.1 14.7 24.8 8.7 31.0 15.3 24.1 11.9 15.3 7.0 23.5 25.6 12.7 12.9 37.2 52.1 15.9 43.9 42.9 32.0 31.2 8.5 34.9 27.3 21.7 31.5 22.0 5.5 38.7 28.5 22.7 16.4 19.2 40.5 31.3 13.7 16.1 9.3 14.9 24.4 13.4 12.5 11.0 47.1 20.4 14.1 14.5 19.4 47.3 13.1 16.6 30.4 26.4 9.0 41.7 33.2 110.3 65.1 21.3 103.4 25.5 71.9 60.4 40.2 29.6 52.3 62.6 48.8 71.3 23.7 37.1 100.2 51.5 8.8 10.1 11.3 9.4 8.2 11.1 13.1 11.0 11.5 9.9 11.5 11.2 14.7 22.4 20.9 0.0 2.3 0.0 0.0 0.0 0.0 0.0 12.7 16.9 0.0 0.0 5.0 9.2 0.0 37.4 17.2 0.0 41.1 34.6 0.0 9.2 9.9 6.4 0.0 0.0 0.0 79.2 14.0 3.9 0.0 15.4 5.1 23.8 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 13.5 0.0 0.0 0.0 0.0 62.9 0.0 0.0 1.0 0.0 0.0 12.8 7.3 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 27.0 13.3 52.4 0.0 0.0 STRAP "MAWD, pt-wd, UNRIP" ENSG00000023734 "Serine/threonine kinase receptor associated protein" Q9Y3F4 12 15882387-15903478 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027320, HPA055557, HPA073876" Approved Enhanced Cytosol NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA027320: AB_1857614, HPA055557: AB_2682849, HPA073876: AB_2686639" "unprognostic (4.64e-3)" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (1.42e-2)" "unprognostic (2.88e-1)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.69e-2)" "unprognostic (3.71e-1)" "unprognostic (2.15e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.93e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.07e-4)" "prognostic unfavorable (5.10e-4)" 70.4 70.2 48.1 54.7 52.5 51.8 49.8 44.4 63.7 51.8 41.4 55.5 46.2 52.2 50.5 60.9 44.4 46.9 93.1 54.8 65.3 84.9 80.3 46.8 54.9 49.9 54.5 40.3 72.0 83.9 58.4 64.6 61.6 49.3 52.8 85.5 48.8 48.7 135.9 44.1 44.9 68.8 47.6 40.3 48.5 50.3 59.0 66.5 77.7 114.6 57.2 70.4 41.3 50.9 195.6 226.2 209.7 179.8 182.3 180.6 280.5 227.9 158.2 200.8 186.4 325.9 167.2 215.6 110.6 233.5 199.3 138.0 254.6 251.0 293.2 291.3 206.1 218.6 163.8 144.7 298.8 258.2 102.0 176.9 209.7 224.6 248.6 221.6 237.9 139.6 170.9 63.9 264.3 137.3 215.6 122.6 743.6 124.8 145.8 162.4 289.7 124.5 232.5 197.8 134.8 228.8 184.7 125.5 258.7 415.8 235.5 135.9 201.3 149.0 177.0 160.3 284.7 73.0 106.1 351.5 183.7 140.1 193.9 74.2 73.9 65.8 66.3 87.4 75.1 76.1 67.8 64.2 92.5 66.7 65.8 70.0 33.7 64.3 80.5 56.8 92.2 84.5 48.1 52.5 44.4 63.7 54.8 65.3 49.9 54.5 61.6 47.6 59.0 50.9 111.7 38.5 45.2 19.9 111.2 243.4 177.6 131.5 116.7 90.1 87.8 65.9 104.0 51.5 84.8 66.2 35.5 154.3 121.2 41.5 275.9 171.1 44.3 63.2 82.1 100.3 106.2 103.7 42.8 137.2 201.2 109.7 61.7 78.6 46.3 112.1 71.7 82.1 108.8 60.6 43.4 59.7 128.1 86.2 143.8 86.2 69.9 89.4 128.1 22.5 99.2 207.9 93.7 24.1 33.9 144.2 66.1 102.0 119.5 218.3 56.0 228.5 58.9 100.9 78.9 96.4 139.0 168.1 80.4 115.6 227.9 295.1 111.3 135.2 95.6 192.5 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" 10.2 10.1 10.3 7.3 10.1 1.3 9.9 9.3 10.0 8.1 13.3 13.7 19.6 9.0 7.9 8.2 7.2 8.4 14.9 8.4 9.3 21.7 20.3 9.5 6.6 10.0 9.8 7.2 7.4 24.9 6.6 9.3 9.8 12.9 15.1 16.4 9.5 11.9 28.7 5.7 16.0 10.7 10.8 9.1 15.5 3.9 10.6 5.1 11.2 29.3 6.4 8.6 6.1 9.7 14.0 9.1 15.3 10.3 11.7 13.4 10.6 10.8 11.1 7.4 8.3 8.7 12.8 0.0 10.0 12.7 7.5 11.6 15.7 11.6 17.5 1.9 8.0 5.2 13.9 11.4 10.3 0.0 1.7 10.5 9.2 9.4 5.3 13.1 16.6 5.8 3.1 2.7 13.4 10.2 7.2 2.1 11.1 13.9 10.9 9.0 22.4 3.9 16.0 20.7 11.1 19.4 14.6 12.0 8.8 9.9 22.7 3.6 18.5 17.7 12.1 6.9 8.7 3.7 15.0 0.0 15.6 1.8 14.9 0.3 3.0 0.1 2.3 3.1 2.7 2.5 2.8 2.7 3.0 2.0 3.8 3.1 0.3 2.3 2.1 1.9 2.3 1.1 10.3 10.1 9.3 10.0 8.4 9.3 10.0 9.8 9.8 10.8 10.6 9.7 36.6 38.5 46.6 0.0 17.8 6.0 28.7 49.4 9.1 44.9 25.9 15.4 89.4 48.6 43.3 75.4 81.3 38.3 13.1 50.1 140.8 49.0 36.9 56.0 26.5 38.4 19.8 5.7 0.0 39.2 31.5 21.7 21.9 85.7 9.5 33.5 37.1 50.4 24.7 30.3 0.0 41.2 44.7 23.6 9.1 9.8 30.4 16.9 14.2 0.0 28.8 37.1 28.8 0.0 0.0 35.7 43.5 41.3 4.2 25.8 87.3 77.0 31.5 88.0 26.3 37.6 27.8 68.9 12.9 12.5 4.8 10.9 17.4 25.0 62.6 30.3 TARDBP "ALS10, TDP-43" ENSG00000120948 "TAR DNA binding protein" Q13148 1 11012344-11030528 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003703, HPA017284" Supported Enhanced Nucleoplasm NA NA 29000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB003703: AB_425904, HPA017284: AB_1857775" "unprognostic (3.72e-3)" "prognostic favorable (1.15e-5)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (8.52e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (4.75e-3)" "unprognostic (2.24e-1)" "unprognostic (2.54e-2)" "unprognostic (2.27e-3)" "unprognostic (2.27e-1)" "unprognostic (1.87e-1)" "unprognostic (2.86e-1)" "unprognostic (2.71e-2)" 83.4 80.1 71.9 87.1 80.6 69.7 83.3 84.7 79.0 93.9 78.1 94.5 77.4 90.9 78.8 111.1 84.1 58.7 93.0 69.4 78.5 93.8 105.5 91.6 106.5 75.5 77.2 103.5 77.2 86.7 89.1 82.7 76.4 90.1 94.5 119.9 86.6 78.8 138.9 96.1 94.5 81.2 74.8 97.4 82.4 68.2 74.7 115.1 96.6 102.9 122.9 87.6 95.8 86.0 244.7 164.4 270.4 143.5 143.9 118.2 160.3 164.7 142.3 263.6 195.5 187.9 175.6 316.3 118.1 180.6 154.3 169.2 333.1 187.6 336.0 175.1 153.8 241.2 275.2 257.9 119.4 290.5 158.9 99.5 211.4 184.5 147.9 143.8 188.6 126.7 319.0 176.4 221.7 195.0 215.6 228.6 221.0 232.2 141.7 256.9 214.4 206.2 186.0 179.1 187.9 150.8 221.3 173.7 128.8 197.1 173.8 200.9 174.8 173.8 207.8 146.3 236.9 133.3 176.2 336.3 116.2 288.2 192.0 38.0 38.0 33.7 46.7 48.6 57.4 55.2 46.9 45.4 61.7 39.6 46.3 50.5 15.4 67.2 50.0 43.1 54.3 36.4 71.9 80.6 84.7 79.0 69.4 78.5 75.5 77.2 76.4 74.8 74.7 86.0 35.5 32.1 74.4 29.4 57.6 114.6 89.9 40.8 52.3 37.6 52.0 38.6 68.0 31.5 57.0 29.5 29.2 63.2 46.3 54.2 33.2 50.8 9.7 50.7 50.0 54.9 66.3 63.5 29.5 54.2 84.5 45.2 34.7 61.7 42.3 45.8 40.0 51.7 50.1 37.0 29.8 50.1 38.7 45.9 46.3 12.3 47.2 37.8 35.6 23.4 54.3 36.2 35.0 37.2 57.2 52.9 36.1 51.6 48.8 71.7 43.2 43.9 54.4 38.8 32.9 42.8 56.9 64.9 32.8 52.4 114.5 73.5 41.3 23.6 52.6 71.3 TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487364-150507609 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" 9.8 16.5 11.8 10.6 11.4 10.0 10.3 11.2 12.5 9.5 10.9 10.3 8.9 8.9 13.0 13.4 11.7 7.7 20.3 11.3 11.5 14.3 25.3 8.6 14.7 12.0 11.5 11.7 8.4 17.7 9.3 8.9 12.7 8.7 11.3 14.7 9.7 9.3 31.9 11.8 9.6 10.0 10.4 12.5 12.0 11.0 11.9 12.6 11.2 31.1 15.4 9.6 9.4 12.8 33.5 27.4 18.1 27.4 19.9 18.2 34.1 15.9 17.2 30.7 30.8 22.4 30.3 48.0 34.2 12.0 21.1 33.8 44.2 36.8 23.5 29.2 38.4 22.7 25.2 22.7 19.7 31.4 33.4 16.2 30.2 23.4 31.6 19.9 20.1 26.4 40.3 32.6 21.8 40.4 27.0 26.0 22.3 46.0 40.2 27.5 23.0 59.8 20.9 15.7 25.5 29.8 24.1 52.5 38.7 25.4 42.3 48.9 11.9 17.8 18.8 14.9 27.2 31.2 39.6 36.2 26.6 36.3 17.6 30.5 15.4 30.5 21.0 27.0 21.3 28.7 20.5 21.2 25.0 25.3 19.6 20.7 2.4 33.2 29.3 16.7 31.4 18.3 11.8 11.4 11.2 12.5 11.3 11.5 12.0 11.5 12.7 10.4 11.9 12.8 6.3 3.2 12.8 6.2 13.2 3.3 5.6 10.4 5.2 15.3 6.2 4.6 22.3 11.5 11.9 7.3 20.9 24.5 8.8 8.2 11.7 11.5 1.6 9.6 12.8 7.4 4.2 11.1 9.3 9.8 14.3 8.4 13.3 11.7 22.2 11.0 6.8 22.6 13.2 15.2 9.1 12.6 6.1 7.7 5.2 2.5 8.4 8.8 3.6 2.8 12.5 7.6 9.2 6.0 9.9 11.9 3.5 7.2 9.9 4.5 8.5 8.8 9.4 16.8 6.6 10.3 8.3 18.2 12.3 7.4 4.0 14.1 10.6 15.8 12.6 4.8 TBC1D4 "AS160, DKFZp779C0666, KIAA0603" ENSG00000136111 "TBC1 domain family member 4" O60343 13 75283503-75482169 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "GTPase activation" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 157.7;Microglial cells: 307.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 25.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 84.7;HUVEC TERT2: 61.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040145, HPA059885" Approved Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA040145: AB_2676860, HPA059885: AB_2684152" "unprognostic (5.44e-3)" "unprognostic (5.23e-1)" "unprognostic (9.85e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-2)" "unprognostic (9.54e-3)" "unprognostic (1.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.87e-1)" "unprognostic (5.02e-2)" "unprognostic (7.53e-2)" "unprognostic (2.64e-1)" "prognostic favorable (1.07e-11)" "unprognostic (6.40e-2)" "unprognostic (3.16e-1)" "unprognostic (8.88e-2)" "unprognostic (3.45e-1)" 14.8 70.6 13.2 15.7 12.5 3.4 20.1 12.5 15.1 10.0 7.1 8.7 4.6 8.5 18.4 9.4 10.7 14.1 33.8 10.5 13.8 25.2 11.7 11.9 34.2 15.9 12.0 44.8 15.0 22.1 5.3 20.7 16.7 12.3 10.4 1.6 27.6 4.3 82.8 21.4 10.3 10.2 12.0 21.0 11.0 5.3 20.0 10.7 24.3 54.9 32.6 8.4 9.2 10.5 12.9 14.9 9.2 0.6 21.3 22.8 12.0 11.0 5.8 8.7 9.6 84.7 15.5 2.7 2.4 15.7 4.2 12.0 23.4 11.0 9.0 42.6 24.3 41.5 19.8 25.9 5.4 20.0 0.5 25.0 19.7 9.7 22.4 14.9 61.6 46.0 12.0 1.3 10.0 6.2 29.4 3.6 12.9 24.7 8.8 26.4 8.7 15.2 8.5 9.3 16.9 5.2 4.8 14.6 8.0 4.8 5.0 0.7 26.2 9.8 12.1 5.2 13.0 0.7 0.1 0.3 17.4 18.5 14.7 5.0 0.4 0.0 0.7 0.1 0.0 0.6 11.2 2.5 0.6 0.5 10.4 4.9 0.5 0.5 0.1 9.9 25.0 2.3 13.2 12.5 12.5 15.1 10.5 13.8 15.9 12.0 16.7 12.0 20.0 10.5 17.8 6.4 29.1 32.3 2.6 36.2 10.0 2.0 19.9 1.6 33.1 41.1 81.4 10.0 6.1 14.7 0.0 10.8 32.4 8.0 15.6 12.3 25.5 14.3 17.7 32.6 21.0 5.0 78.0 7.4 9.7 17.3 7.1 8.7 5.1 81.5 26.0 19.4 26.6 1.7 157.7 10.7 24.4 24.8 25.8 5.2 3.7 12.9 21.4 307.3 33.6 0.4 1.0 40.7 5.1 4.9 2.9 7.2 2.1 16.4 3.4 10.8 3.9 0.6 6.6 24.8 21.6 2.4 7.7 24.2 44.2 4.9 25.2 8.1 15.5 10.6 TCAIM "C3orf23, DKFZp313N0621, TOAG-1" ENSG00000179152 "T cell activation inhibitor, mitochondrial" Q8N3R3 3 44338119-44409451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 42.9" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.15e-1)" "unprognostic (9.21e-2)" "unprognostic (1.98e-1)" "unprognostic (4.24e-1)" "unprognostic (1.82e-1)" "unprognostic (8.55e-2)" "unprognostic (1.93e-3)" "unprognostic (5.07e-3)" "unprognostic (5.60e-2)" "prognostic favorable (2.19e-7)" "unprognostic (4.03e-1)" "unprognostic (1.49e-1)" "unprognostic (4.65e-2)" "prognostic favorable (2.81e-4)" 8.6 8.5 7.9 6.7 8.6 4.8 6.6 12.0 10.5 5.9 8.7 9.6 8.2 6.7 8.4 10.1 6.4 9.7 19.4 7.0 8.8 24.2 42.9 9.3 6.9 9.8 9.1 8.1 5.7 11.4 3.5 9.2 9.8 9.9 9.8 10.3 4.7 5.9 22.0 7.7 9.2 8.7 8.7 7.2 9.4 5.6 9.1 8.4 7.4 18.9 7.9 9.9 4.2 10.9 15.5 7.5 8.3 10.6 13.5 10.8 17.3 14.8 17.4 15.7 16.5 7.0 35.6 22.0 10.8 10.0 11.4 7.1 8.0 16.5 17.4 9.2 8.8 15.5 10.4 16.5 23.5 25.9 14.4 12.7 33.0 15.9 17.9 14.9 21.3 22.1 19.2 12.5 16.2 10.8 25.2 13.2 7.8 17.4 17.5 5.0 9.1 16.8 36.6 24.2 8.3 20.3 16.5 22.6 24.1 14.4 17.1 15.3 18.1 9.4 11.2 24.7 22.4 8.4 16.5 16.1 21.2 20.9 16.1 14.8 7.9 10.6 3.6 10.0 4.2 2.3 4.7 3.6 10.3 3.7 3.8 5.5 3.6 3.6 10.1 5.5 9.4 4.0 7.9 8.6 12.0 10.5 7.0 8.8 9.8 9.1 9.8 8.7 9.1 10.9 12.5 9.6 16.1 38.5 7.4 10.3 9.3 12.2 12.0 18.9 11.1 8.3 30.1 24.3 10.5 14.7 12.5 13.6 14.5 12.0 60.7 23.6 3.3 10.3 7.8 11.6 6.0 7.2 55.8 20.9 21.0 7.5 12.2 17.7 21.0 15.1 15.0 47.7 20.0 25.2 90.4 17.1 12.2 18.8 10.1 2.0 8.7 17.6 7.2 20.6 16.0 17.1 9.2 42.7 47.1 25.6 14.7 4.9 7.4 10.8 11.7 46.2 11.4 13.1 13.1 8.1 12.8 6.2 11.0 16.8 9.5 13.4 8.2 14.6 17.3 13.4 TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023788: AB_1848818, HPA053044: AB_2682023" "unprognostic (1.22e-1)" "unprognostic (1.18e-2)" "unprognostic (1.11e-3)" "unprognostic (3.31e-2)" "unprognostic (7.89e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (9.20e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (2.11e-1)" "unprognostic (6.18e-3)" "unprognostic (9.39e-2)" "unprognostic (4.79e-2)" "unprognostic (7.90e-2)" "unprognostic (1.92e-1)" "unprognostic (2.23e-1)" "unprognostic (8.37e-3)" 4.9 6.0 4.4 5.9 4.6 2.2 6.7 5.7 6.0 4.0 5.5 5.7 5.6 4.9 4.1 5.2 4.8 4.1 8.9 4.6 4.4 9.6 8.8 4.0 7.3 4.5 4.4 4.8 3.3 6.6 3.2 6.8 4.6 5.0 6.6 6.9 5.4 4.8 6.8 5.3 4.6 5.1 4.3 5.7 5.1 4.2 4.6 5.4 5.4 11.7 6.7 5.4 2.9 5.1 12.8 19.2 10.7 14.9 12.7 12.4 10.1 13.1 9.5 23.7 21.4 15.6 7.2 17.4 12.7 8.1 15.5 21.6 18.6 9.1 22.4 5.5 23.9 8.8 15.1 15.5 8.5 18.7 11.2 7.9 11.7 13.4 6.9 7.2 11.9 12.4 19.1 14.3 13.9 11.7 16.0 24.3 8.9 19.6 12.1 10.5 22.9 17.6 19.2 14.4 16.3 7.5 9.8 11.7 15.4 10.9 23.7 14.1 7.8 10.9 14.7 11.2 13.8 7.9 14.0 16.2 7.3 13.8 13.2 2.6 7.7 6.5 6.4 12.2 8.8 9.8 8.2 6.5 8.1 6.3 9.9 9.2 2.3 8.6 9.9 7.0 10.0 7.1 4.4 4.6 5.7 6.0 4.6 4.4 4.5 4.4 4.6 4.3 4.6 5.1 10.1 16.0 10.6 13.7 11.3 4.1 8.0 22.6 9.1 17.8 6.8 6.9 5.8 11.5 13.6 9.2 8.4 26.0 11.5 5.4 25.4 13.4 10.4 12.6 15.3 9.6 5.4 6.9 27.1 8.5 17.3 10.2 5.1 7.8 5.1 17.2 10.4 10.1 20.4 16.8 27.3 7.4 22.4 7.8 3.0 6.3 8.1 9.6 7.2 21.5 14.0 15.0 16.5 27.2 32.2 12.5 5.6 7.5 7.1 5.2 9.4 17.7 17.8 19.4 19.7 11.0 11.6 27.7 17.8 8.7 4.3 17.8 10.0 18.9 7.9 4.7 TEX261 "MGC32043, TEG-261" ENSG00000144043 "Testis expressed 261" Q6UWH6 2 70985942-70994873 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016631 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA016631: AB_2240434" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (4.23e-4)" "unprognostic (5.52e-3)" "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (3.15e-2)" "unprognostic (3.70e-3)" "unprognostic (3.36e-1)" "unprognostic (5.59e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.99e-1)" 39.5 38.8 30.8 21.5 34.8 20.0 29.7 33.1 31.2 32.2 39.1 28.3 25.0 25.4 45.5 27.5 35.3 22.7 36.0 29.3 32.7 41.1 38.8 30.4 22.0 38.5 34.5 39.6 47.5 66.1 29.2 25.0 33.5 31.6 32.7 43.9 36.0 34.3 56.4 20.9 25.6 34.0 32.9 23.5 30.0 36.9 33.4 25.7 46.1 54.3 27.0 26.2 21.6 33.4 61.9 57.1 39.4 50.3 116.4 58.9 44.7 69.8 65.6 79.1 49.6 67.5 49.8 50.2 25.9 122.5 74.7 45.6 75.3 82.7 113.8 38.4 62.8 60.1 28.7 71.8 68.3 70.7 48.7 53.7 54.3 76.2 51.6 43.4 81.5 51.3 75.7 32.4 93.6 48.2 61.2 39.3 26.2 98.7 66.4 43.1 120.7 43.1 57.7 53.1 64.0 33.8 72.3 70.9 46.0 26.2 46.3 41.3 66.1 96.8 83.6 52.4 93.8 25.3 23.9 58.4 84.4 91.7 83.2 8.7 3.8 7.7 3.4 3.9 2.9 1.8 3.7 4.6 2.9 2.7 4.1 3.3 2.8 2.6 3.9 3.1 3.3 2.1 30.8 34.8 33.1 31.2 29.3 32.7 38.5 34.5 33.5 32.9 33.4 33.4 14.7 3.2 14.7 9.4 11.3 8.3 10.7 8.2 5.7 14.7 20.6 14.9 22.9 20.0 8.4 23.9 37.5 16.4 9.0 21.8 7.9 24.9 15.7 10.8 11.9 15.5 8.4 17.4 8.0 23.8 17.4 16.3 12.2 13.3 2.5 17.1 16.4 35.2 19.5 8.4 7.5 18.2 8.2 18.3 6.4 28.5 15.8 11.9 19.6 6.5 13.0 28.1 14.4 15.1 12.6 21.1 14.9 18.4 7.4 12.9 24.4 18.3 5.5 72.9 0.0 16.7 15.0 45.3 11.2 12.8 7.5 17.9 8.7 14.4 18.9 7.7 THOC7 "FLJ23445, fSAP24, NIF3L1BP1" ENSG00000163634 "THO complex 7" Q6I9Y2 3 63833870-63863868 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044143 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Cytosol" "HPA044143: AB_10794892" "unprognostic (4.33e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-2)" "unprognostic (2.86e-1)" "unprognostic (1.20e-3)" "unprognostic (3.53e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (9.90e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.31e-1)" 54.7 63.5 57.1 43.2 60.0 80.1 75.1 58.1 85.1 54.4 52.0 69.9 64.2 50.5 53.2 73.1 43.0 48.6 88.0 61.5 59.1 67.8 73.5 40.9 68.1 58.4 59.1 44.4 62.3 52.1 33.5 53.5 57.1 43.8 69.1 64.5 50.5 49.5 103.5 64.2 53.7 59.6 57.3 38.2 49.1 47.6 57.8 72.3 44.4 104.0 68.0 60.8 50.3 61.1 141.2 83.5 95.6 23.9 125.1 172.5 89.6 120.2 126.9 139.2 140.1 101.6 151.5 168.3 49.1 155.1 139.2 79.3 107.5 190.4 194.1 169.6 75.5 150.2 102.8 117.2 130.1 212.6 69.6 123.9 157.2 118.4 213.1 137.6 155.1 110.0 116.8 158.6 170.2 1032.4 186.4 186.9 120.4 304.8 65.5 132.3 89.7 227.4 245.4 128.0 47.3 107.8 105.0 147.6 171.6 93.9 93.6 289.6 113.6 100.8 105.9 125.1 216.3 101.3 162.3 204.1 125.3 268.3 133.5 73.1 40.4 33.1 38.7 47.7 54.0 46.7 47.9 53.2 59.0 31.5 40.5 43.4 23.4 55.6 41.9 54.0 61.7 35.6 57.1 60.0 58.1 85.1 61.5 59.1 58.4 59.1 57.1 57.3 57.8 61.1 82.6 89.8 45.0 14.4 59.2 61.6 91.2 179.9 70.6 53.5 70.9 121.3 143.8 81.5 102.9 84.6 18.8 180.3 66.0 62.1 207.4 145.2 84.7 100.7 75.6 57.8 55.2 159.7 26.8 126.9 166.1 65.4 47.4 73.8 54.4 74.3 44.6 78.1 111.6 48.8 26.4 106.3 101.7 75.6 58.9 89.7 88.9 70.2 67.6 14.0 173.1 82.5 93.7 12.5 18.9 127.6 86.7 71.5 53.3 96.6 108.8 241.2 102.1 73.1 52.6 66.9 83.4 244.9 54.5 116.6 71.6 213.4 68.0 80.7 133.2 95.7 THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2" ENSG00000151090 "Thyroid hormone receptor beta" P10828 3 24117153-24495756 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 199.2;Cone photoreceptor cells: 164.7;Excitatory neurons: 688.0;Inhibitory neurons: 631.3;Oligodendrocyte precursor cells: 329.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 7.7;basal ganglia: 15.1;cerebral cortex: 17.6;hippocampal formation: 18.5;white matter: 6.7" "Group enriched" "Detected in some" 5 "basophil: 7.2;naive B-cell: 2.2" "Group enriched" "Detected in many" 15 "B-cells: 2.2;granulocytes: 7.2" "Cell line enhanced" "Detected in many" "K-562: 45.6;RT4: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002008, CAB002009, HPA061035" Approved Supported "Nuclear bodies" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "CAB002008: , CAB002009: , HPA061035: AB_2684422" "unprognostic (1.82e-1)" "unprognostic (4.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.20e-6)" "unprognostic (3.37e-1)" "unprognostic (2.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-3)" "unprognostic (2.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.46e-8)" "unprognostic (1.32e-3)" "unprognostic (6.75e-2)" "unprognostic (2.73e-2)" "unprognostic (3.34e-2)" 11.1 4.9 7.7 1.7 15.1 1.0 10.0 0.0 17.6 2.8 0.0 11.7 2.5 7.0 1.8 6.4 3.8 2.2 7.7 18.5 2.0 12.1 20.1 5.0 1.5 0.0 0.0 2.3 9.0 7.3 15.7 4.4 0.0 7.5 8.4 20.1 6.2 7.7 23.6 6.8 3.9 7.0 0.0 5.7 8.3 0.7 1.4 3.6 4.4 27.0 1.4 8.9 4.2 6.7 10.3 3.1 0.6 0.1 17.4 8.8 6.7 0.5 2.1 1.5 3.2 6.7 9.7 0.1 2.5 6.8 1.1 15.4 10.8 3.9 1.0 0.0 6.4 0.0 2.5 8.9 0.5 0.0 0.0 16.0 7.3 0.2 1.2 3.5 0.0 0.0 45.6 0.0 1.5 0.6 0.0 0.0 6.5 0.6 3.4 0.0 0.0 0.0 10.0 32.7 1.7 0.6 16.5 8.9 0.2 4.6 9.7 0.0 0.9 3.9 3.0 0.0 1.9 0.1 0.5 0.0 2.7 0.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 7.7 15.1 0.0 17.6 18.5 2.0 0.0 0.0 0.0 0.0 1.4 6.7 3.0 3.2 11.4 199.2 3.3 9.9 29.5 13.2 1.8 17.9 24.5 18.7 11.6 8.6 14.1 23.9 164.7 12.4 0.0 39.9 1.9 2.4 2.3 3.4 0.5 6.0 25.2 3.8 688.0 12.5 23.2 13.7 16.3 5.7 0.0 0.3 7.5 37.7 1.7 0.0 631.3 8.1 10.2 11.3 11.7 2.4 0.6 4.6 1.8 97.4 0.2 11.7 0.0 329.2 32.4 10.3 17.5 2.2 0.1 40.1 4.8 8.1 10.3 21.8 6.6 12.0 7.5 0.3 0.7 5.1 23.9 5.5 1.0 0.4 9.8 81.3 TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" 31.4 48.3 29.3 35.4 30.6 36.8 29.3 31.2 35.8 27.4 34.9 35.2 31.4 25.7 41.1 31.9 20.9 19.0 72.2 31.3 32.5 42.2 80.6 23.7 30.9 30.2 30.6 18.5 23.4 55.8 24.8 31.3 31.0 25.0 38.0 33.3 23.0 28.4 86.1 20.9 23.9 35.3 30.5 24.9 29.1 19.7 30.7 30.3 38.2 94.9 35.8 42.8 23.2 29.4 89.1 88.9 78.5 94.9 64.5 67.2 132.5 138.4 98.0 110.5 98.4 104.8 89.7 122.5 49.7 118.6 81.1 69.2 145.3 82.4 118.3 90.4 90.7 67.7 119.1 99.7 66.7 145.5 69.5 78.0 89.8 113.2 93.9 79.5 117.4 75.4 173.1 66.7 131.7 56.9 78.9 78.3 99.6 88.3 47.0 76.5 91.4 152.6 136.2 83.1 118.0 83.2 84.6 213.5 130.7 98.7 118.5 97.0 95.2 73.6 78.7 86.7 146.4 99.9 115.9 102.3 78.4 109.2 84.2 18.5 32.0 29.2 21.7 44.5 28.6 30.3 23.5 28.1 50.1 23.6 22.4 26.2 7.7 29.7 46.7 33.6 37.0 32.2 29.3 30.6 31.2 35.8 31.3 32.5 30.2 30.6 31.0 30.5 30.7 29.4 31.7 38.5 37.2 9.4 54.7 92.2 100.2 123.3 34.1 24.1 43.2 36.2 129.5 37.1 73.0 38.6 35.5 115.2 44.2 38.8 137.0 94.5 69.7 40.1 55.2 46.0 34.0 36.6 18.1 86.0 187.0 55.9 40.2 48.1 55.2 37.9 32.9 168.0 114.8 35.3 17.4 58.1 81.4 44.0 177.7 32.0 33.5 52.8 53.4 4.7 80.4 49.4 26.8 6.6 14.9 109.4 30.4 38.4 98.6 85.0 37.2 131.8 55.8 31.7 26.3 46.6 75.3 42.6 61.5 60.6 98.9 265.6 46.2 62.9 58.3 118.1 TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.2;Hepatocytes: 68.3;Suprabasal keratinocytes: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 59000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Mitochondria "HPA003628: AB_1080284" "prognostic unfavorable (7.89e-5)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (8.87e-5)" "unprognostic (2.06e-1)" "unprognostic (9.28e-3)" "unprognostic (5.14e-3)" "unprognostic (8.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-3)" "unprognostic (6.41e-2)" "unprognostic (8.57e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (1.70e-1)" "unprognostic (3.86e-2)" 5.1 5.6 4.3 6.5 4.4 6.9 7.6 5.1 5.2 4.4 4.8 7.2 6.6 4.2 4.7 7.0 5.6 3.6 10.9 4.5 5.3 9.2 25.3 3.1 8.2 4.5 5.5 5.9 5.2 6.7 1.9 6.3 4.5 6.5 7.5 5.0 6.0 3.7 10.0 6.5 6.3 4.8 5.0 4.5 4.2 3.2 5.2 6.8 6.5 14.0 8.7 6.5 3.1 4.3 31.5 30.0 17.1 33.8 13.3 15.0 20.3 23.5 11.4 20.0 40.6 26.4 21.3 38.0 29.7 17.8 36.5 27.7 46.2 24.5 33.3 17.7 29.9 62.8 44.7 46.5 12.7 39.9 217.8 15.0 21.5 30.0 18.8 9.6 19.7 15.9 51.0 40.8 26.8 50.7 18.3 39.1 55.3 46.4 49.3 30.2 31.1 44.9 18.3 21.1 22.7 20.9 28.6 22.8 22.5 18.8 19.1 19.3 14.2 27.5 31.5 40.6 26.1 18.7 50.8 45.9 14.6 53.8 22.2 1.2 3.8 0.2 4.9 5.8 7.0 12.1 6.8 7.2 4.6 11.9 10.3 8.4 0.4 5.2 3.1 11.7 3.8 4.3 4.3 4.4 5.1 5.2 4.5 5.3 4.5 5.5 4.5 5.0 5.2 4.3 7.0 3.2 4.4 1.3 10.7 102.2 39.6 27.6 31.9 7.6 11.2 16.8 25.8 5.7 14.1 11.0 6.2 38.4 8.7 7.5 39.2 13.5 0.7 9.0 10.8 10.2 8.4 27.4 2.8 10.9 47.6 13.0 7.1 7.3 16.5 9.3 5.3 68.3 21.1 3.3 2.8 8.6 22.4 7.2 13.9 0.5 6.5 7.5 14.2 1.9 5.0 5.4 3.1 1.0 0.7 15.4 6.7 2.6 13.8 36.2 8.0 39.9 9.1 8.5 0.0 9.6 16.7 2.9 10.9 27.7 88.5 36.7 6.9 12.4 18.0 27.8 TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA046058: AB_2679519, HPA055621: AB_2682865" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (1.68e-1)" "unprognostic (2.20e-2)" "unprognostic (5.79e-1)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" 30.9 36.3 25.4 16.5 26.0 23.2 35.8 27.3 36.5 29.4 27.6 27.7 20.5 30.3 45.3 21.4 29.9 26.0 45.4 25.2 27.0 38.8 29.3 27.4 26.5 26.7 27.0 36.4 21.8 41.6 20.4 35.7 26.8 33.3 28.5 26.2 30.1 22.5 40.9 19.8 25.0 29.3 27.1 23.9 24.4 34.9 25.9 25.1 40.6 35.3 20.3 30.1 20.7 28.4 31.3 15.0 22.8 18.2 68.1 66.2 29.2 54.5 55.2 26.4 35.0 9.7 39.0 25.3 70.9 45.9 52.7 34.8 29.2 39.7 40.5 41.3 34.4 28.2 23.0 21.8 66.7 40.9 48.0 74.2 67.0 30.5 38.0 64.4 50.5 33.6 32.7 47.7 64.7 10.1 20.9 32.0 24.9 27.5 21.4 17.9 43.1 31.5 78.4 24.3 25.4 30.9 32.5 64.1 102.6 30.5 35.1 43.2 45.3 35.3 17.8 19.8 41.9 40.0 39.4 30.8 61.3 39.4 31.8 52.8 18.7 44.9 16.1 23.7 16.6 24.2 18.6 19.7 18.6 20.1 17.2 19.9 12.2 23.3 26.8 36.4 24.3 19.4 25.4 26.0 27.3 36.5 25.2 27.0 26.7 27.0 26.8 27.1 25.9 28.4 49.5 41.7 40.2 32.3 49.0 78.3 91.9 205.2 59.2 60.3 67.7 56.6 40.5 48.6 99.9 79.1 60.5 51.2 47.4 46.5 39.2 50.3 6.5 43.3 34.7 59.2 43.9 42.1 42.3 45.3 60.0 84.3 29.0 42.2 61.5 37.6 80.7 54.2 50.3 69.0 46.9 41.3 158.7 58.7 53.8 9.9 79.9 48.1 90.7 43.1 54.1 99.2 63.8 50.3 63.4 54.2 60.4 53.0 51.4 110.0 45.9 67.6 100.0 70.1 39.5 75.3 60.0 172.1 72.5 58.6 76.4 53.5 47.3 42.0 43.0 110.1 TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Vesicles, Intermediate filaments" "HPA017678: AB_1858086, HPA017682: AB_1858087" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (7.42e-2)" "unprognostic (8.58e-2)" "unprognostic (4.18e-2)" "unprognostic (7.59e-3)" "unprognostic (3.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.10e-3)" "unprognostic (5.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.77e-1)" 12.1 12.2 7.2 20.7 7.5 17.5 10.6 7.2 7.6 18.8 9.3 25.8 18.5 16.3 8.5 14.3 15.3 15.8 13.0 7.4 5.5 12.1 13.5 12.4 25.4 6.1 7.5 16.3 19.0 27.5 11.1 18.3 6.1 16.6 23.2 11.4 13.4 11.5 24.4 24.1 19.4 16.5 6.6 18.4 26.2 14.7 10.3 18.4 12.8 22.3 23.1 14.1 10.4 8.6 26.1 15.7 28.8 21.0 29.6 35.8 31.4 37.8 36.5 18.9 22.7 20.3 36.8 41.3 20.4 39.3 32.2 18.4 30.5 50.5 28.0 29.4 19.8 30.0 10.6 29.3 33.4 28.2 38.6 34.4 20.2 33.7 34.7 32.0 23.5 19.8 18.1 42.8 58.2 15.7 20.6 17.9 15.8 20.2 33.4 29.7 18.3 18.3 19.3 30.7 32.3 15.7 24.4 16.7 23.2 30.7 14.0 25.8 28.1 49.1 22.4 23.9 14.7 18.1 26.8 20.6 38.5 24.3 33.9 3.7 1.3 3.6 1.7 1.6 1.9 2.1 1.5 1.7 1.7 1.9 1.7 2.3 0.9 2.5 1.6 2.4 1.0 1.0 7.2 7.5 7.2 7.6 7.4 5.5 6.1 7.5 6.1 6.6 10.3 8.6 29.4 16.0 27.9 90.1 41.2 19.8 17.7 16.3 24.5 28.3 17.3 16.0 34.7 15.7 23.4 20.2 22.9 15.4 33.1 62.2 3.9 9.7 14.4 88.9 33.9 19.3 30.1 23.5 113.1 24.0 12.7 23.5 60.1 86.8 23.5 21.3 22.9 26.0 24.5 25.2 99.7 45.6 10.2 29.2 18.5 20.1 20.8 35.8 12.4 87.1 47.0 14.1 9.2 92.5 129.8 18.1 40.1 19.2 36.3 17.9 27.4 7.0 38.2 19.3 13.1 31.9 24.9 21.2 26.0 25.0 25.6 13.5 22.4 28.0 36.6 16.0 TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Distal enterocytes: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" 16.9 10.3 11.4 9.6 11.8 19.0 12.3 6.8 9.7 5.5 14.3 18.8 21.5 5.3 6.0 13.8 8.1 5.1 22.7 9.0 12.1 11.1 2.0 17.9 6.7 13.5 13.0 13.8 25.4 8.3 9.6 5.2 11.2 8.9 21.2 3.6 9.8 14.4 27.5 20.3 19.2 6.9 8.2 8.4 14.0 1.9 12.3 12.6 13.8 19.3 8.0 5.8 6.8 8.6 10.8 24.3 19.5 12.8 23.7 17.3 11.9 5.3 12.4 11.0 7.1 19.1 16.6 8.6 35.2 8.3 27.1 15.6 17.1 27.9 10.8 23.9 11.7 58.5 13.0 8.1 13.9 26.1 80.1 24.0 48.4 19.9 27.2 30.2 21.8 15.2 18.4 10.2 19.7 21.6 27.4 33.1 17.5 36.9 17.3 12.4 15.1 7.2 17.5 11.3 18.2 20.3 34.0 33.1 15.9 18.1 9.6 25.7 49.0 9.3 6.8 11.0 7.7 5.9 7.9 6.9 24.3 32.0 25.3 59.7 3.3 14.2 0.6 2.9 1.6 0.2 0.7 0.6 2.7 0.6 0.4 0.5 16.3 2.3 1.8 0.5 1.0 1.8 11.4 11.8 6.8 9.7 9.0 12.1 13.5 13.0 11.2 8.2 12.3 8.6 2.9 3.2 36.1 84.5 3.7 4.8 3.7 4.7 4.6 1.2 11.7 9.1 21.3 11.5 6.9 16.5 2.1 2.7 3.5 53.0 3.9 4.6 0.5 6.7 3.8 6.0 27.6 14.5 22.9 11.4 6.3 3.1 7.7 10.7 3.8 4.3 6.4 1.7 13.6 0.0 31.4 12.7 10.2 25.1 9.4 1.3 1.8 12.5 1.8 24.4 28.1 1.0 4.1 34.2 7.6 13.5 15.0 1.5 1.6 9.0 31.9 3.3 5.4 1.3 0.0 6.4 4.1 0.2 0.3 10.4 8.0 2.7 5.2 3.8 21.2 12.3 TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "HPA016830: AB_1858107" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (6.76e-2)" "unprognostic (1.44e-1)" "unprognostic (4.45e-1)" "unprognostic (3.43e-2)" "unprognostic (7.60e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-2)" "unprognostic (4.42e-1)" "unprognostic (5.32e-3)" "unprognostic (1.00e-1)" 11.4 10.9 8.0 16.9 9.5 8.1 20.6 9.9 8.8 13.3 12.4 27.2 34.4 8.1 9.8 31.1 12.2 11.0 15.7 8.3 10.5 38.3 24.7 16.2 18.7 10.5 9.8 4.2 16.2 15.2 6.9 9.4 10.4 7.5 20.3 13.8 12.5 13.0 25.2 21.7 30.1 14.8 10.8 18.2 14.7 7.1 9.1 20.1 13.6 21.9 30.9 19.4 16.6 12.3 35.9 45.5 30.8 18.2 47.7 22.0 18.6 28.4 33.8 32.7 28.5 22.2 32.3 66.2 38.0 54.4 27.2 45.9 27.1 30.6 43.8 48.5 32.4 38.4 29.4 25.1 13.1 40.9 37.1 20.0 33.7 41.8 13.6 26.1 35.6 58.4 23.0 37.9 49.9 17.4 39.7 11.9 17.3 22.3 30.1 29.8 45.4 37.8 30.0 82.1 33.7 26.8 49.6 25.5 12.9 23.5 38.2 12.1 35.1 45.8 22.2 20.1 25.9 73.9 101.4 47.7 19.4 11.7 50.0 26.0 27.1 10.4 33.2 34.3 25.7 102.3 26.1 28.2 47.6 118.6 25.2 30.3 2.3 28.8 31.3 134.5 29.8 33.7 8.0 9.5 9.9 8.8 8.3 10.5 10.5 9.8 10.4 10.8 9.1 12.3 12.8 22.4 16.3 9.8 44.7 19.1 18.8 32.7 14.8 12.9 11.7 5.8 22.4 12.8 20.1 25.8 12.5 13.6 37.9 21.9 11.7 15.8 16.4 7.4 6.0 14.9 19.9 9.9 7.2 21.6 25.1 11.8 6.6 7.5 15.8 7.4 16.4 31.1 25.9 15.2 9.2 14.5 34.6 32.1 33.7 75.3 7.5 24.2 23.2 5.6 21.4 11.0 22.6 9.5 12.2 22.1 20.2 13.5 54.8 6.9 51.2 46.1 30.6 8.8 6.6 7.5 9.0 4.4 8.4 43.8 46.5 4.8 12.4 7.7 27.4 16.6 TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.4;tongue: 62.1" "Cell type enhanced" "Detected in many" "Early spermatids: 267.0;Late spermatids: 488.4;Spermatocytes: 157.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "HPA018465: AB_1858116" "unprognostic (3.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-2)" "unprognostic (3.11e-3)" "unprognostic (1.88e-2)" "unprognostic (3.54e-2)" "unprognostic (5.82e-3)" "unprognostic (5.80e-2)" "prognostic favorable (7.96e-4)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (3.89e-3)" "unprognostic (9.98e-2)" 7.6 14.0 6.2 7.1 11.6 19.1 4.7 19.5 9.2 7.6 6.3 12.5 6.4 8.3 17.3 7.2 7.2 6.8 30.7 7.4 12.9 29.2 15.3 5.7 8.1 8.3 8.4 18.3 4.9 9.2 5.8 4.6 10.6 8.0 11.8 10.4 4.0 6.8 77.4 6.0 10.7 8.1 5.9 6.3 6.7 28.6 9.0 4.9 28.8 62.1 5.1 5.0 4.0 19.6 16.7 25.6 19.6 30.9 110.5 24.3 40.8 23.4 15.3 22.6 23.3 40.0 22.5 38.4 11.8 8.5 36.4 11.6 28.4 13.5 24.4 29.0 37.8 15.8 16.2 24.7 15.1 48.1 32.7 23.0 11.8 15.5 21.6 7.1 9.1 26.6 84.3 33.2 14.0 46.4 33.6 14.5 15.1 48.7 27.1 22.3 61.4 18.4 10.3 13.2 34.1 8.3 24.2 39.4 17.9 13.0 49.2 33.5 4.9 20.5 20.2 78.9 24.7 40.7 109.8 19.1 38.2 52.2 41.7 15.6 20.2 53.8 13.2 29.6 17.7 56.6 18.3 15.8 23.3 56.6 38.9 24.9 3.1 28.2 26.8 51.7 18.0 24.2 6.2 11.6 19.5 9.2 7.4 12.9 8.3 8.4 10.6 5.9 9.0 19.6 9.2 0.0 2.7 7.5 27.8 30.3 24.9 6.2 15.9 12.9 8.9 3.9 55.5 15.7 8.4 25.8 29.2 12.0 16.4 19.1 66.5 8.9 267.0 2.2 7.2 9.9 31.8 7.2 12.4 6.9 19.0 24.2 9.2 3.0 15.8 11.3 3.6 24.4 30.9 11.8 28.6 12.9 18.3 7.9 33.2 488.4 85.1 21.4 32.0 6.5 18.3 30.6 3.1 65.4 30.6 6.3 12.2 44.8 20.2 55.1 10.9 47.0 7.6 12.3 118.3 18.2 58.1 157.8 47.6 13.0 32.7 21.2 13.8 39.7 19.0 20.2 TMEM65 ENSG00000164983 "Transmembrane protein 65" Q6PI78 8 124306189-124372701 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.6;Horizontal cells: 99.3;Inhibitory neurons: 139.8;Microglial cells: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025020 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA025020: AB_2205178" "prognostic unfavorable (2.17e-4)" "unprognostic (3.52e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.24e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (2.26e-2)" "unprognostic (1.84e-1)" "unprognostic (4.71e-2)" "unprognostic (7.95e-2)" "unprognostic (8.26e-2)" "unprognostic (5.67e-2)" "unprognostic (8.25e-2)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (3.78e-1)" 3.7 3.1 5.1 4.9 5.1 3.5 5.1 5.2 5.4 5.5 3.4 4.0 15.4 4.8 2.2 5.6 3.0 4.7 11.9 4.9 5.0 4.7 2.7 3.6 4.5 3.8 5.8 4.2 4.8 6.6 2.1 3.3 4.8 2.8 4.5 2.7 8.6 2.0 13.9 10.1 5.5 3.7 3.7 4.7 2.8 1.7 6.2 3.7 5.3 12.4 4.5 3.2 5.3 4.6 7.9 5.4 11.2 4.0 3.4 6.1 0.9 4.5 4.4 6.9 7.9 0.9 3.1 7.4 4.4 8.0 5.3 3.6 5.8 4.3 8.2 23.2 5.9 5.0 4.6 1.6 9.5 3.4 4.8 4.4 8.1 10.0 7.9 9.4 15.8 3.6 2.3 6.2 8.5 6.1 2.4 1.3 3.0 3.5 7.5 1.4 10.6 4.5 7.3 3.4 9.1 5.4 16.6 41.9 7.8 5.7 3.7 4.3 10.3 5.8 13.9 19.4 7.7 4.2 3.3 3.0 8.2 24.6 8.4 0.4 0.1 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.3 0.4 0.1 0.2 0.3 0.0 5.1 5.1 5.2 5.4 4.9 5.0 3.8 5.8 4.8 3.7 6.2 4.6 14.0 12.8 3.9 34.3 15.1 13.4 9.4 3.0 11.4 6.0 14.0 11.8 37.2 15.7 4.8 7.3 0.0 0.6 10.0 17.0 23.5 10.9 3.9 12.1 12.9 14.0 1.2 6.3 72.6 7.8 1.6 13.0 5.6 9.7 1.3 31.2 23.9 4.7 8.9 99.3 139.8 3.7 4.1 19.1 10.5 1.0 9.9 19.8 8.8 70.3 9.3 4.4 14.4 52.3 45.0 9.8 4.7 11.7 10.2 7.8 5.3 19.2 5.8 2.3 6.6 25.9 8.9 3.3 4.5 31.9 12.5 0.7 14.8 7.5 5.2 11.6 TMEM69 "C1orf154, FLJ21029" ENSG00000159596 "Transmembrane protein 69" Q5SWH9 1 45688181-45694436 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026993 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA026993: AB_10601824" "prognostic favorable (2.24e-4)" "unprognostic (2.47e-1)" "unprognostic (5.25e-2)" "unprognostic (1.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.66e-8)" "unprognostic (4.05e-2)" "unprognostic (1.59e-3)" "unprognostic (5.17e-2)" "unprognostic (3.98e-3)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (1.49e-2)" "unprognostic (1.96e-1)" "unprognostic (4.41e-3)" "unprognostic (3.65e-2)" 17.4 19.5 12.0 17.2 12.4 9.4 21.0 13.2 14.4 14.6 15.6 19.0 22.7 15.6 26.7 21.5 17.1 15.8 31.8 12.4 12.9 16.3 19.4 12.1 26.9 12.6 13.0 23.5 14.0 31.9 5.9 19.7 13.0 19.1 22.9 16.6 21.2 15.4 23.9 21.2 17.0 13.9 12.4 16.2 15.2 13.3 13.0 21.2 21.1 25.4 27.7 26.0 8.7 13.3 50.1 13.2 33.9 25.9 25.1 32.6 81.6 31.6 37.1 52.5 50.7 34.2 24.8 59.8 20.4 30.9 38.1 64.9 26.5 77.2 56.3 40.1 31.6 126.2 30.6 38.2 45.3 59.6 58.2 38.8 75.5 50.7 32.6 34.3 44.7 57.8 75.5 37.4 32.4 17.9 32.9 41.3 77.8 30.0 33.4 51.1 29.2 59.9 56.7 57.2 36.8 34.6 32.8 88.8 56.2 61.2 47.0 59.1 32.5 23.9 40.0 49.8 38.9 29.9 41.6 44.8 32.5 43.0 36.5 12.2 25.0 10.2 9.0 25.8 11.7 16.6 12.8 10.5 22.1 15.5 14.5 11.4 9.6 9.2 34.6 12.5 12.8 13.6 12.0 12.4 13.2 14.4 12.4 12.9 12.6 13.0 13.0 12.4 13.0 13.3 10.8 0.0 14.9 9.8 22.4 20.1 22.8 49.2 37.5 11.0 19.1 21.7 9.1 12.8 26.8 18.4 0.0 61.4 7.7 16.7 43.0 22.7 1.9 13.4 12.6 14.3 24.0 32.4 9.1 17.8 36.1 17.1 35.7 11.6 6.3 12.1 14.6 14.4 37.7 6.7 9.7 21.3 34.6 38.9 11.9 4.4 18.6 21.8 17.8 2.8 23.9 14.5 14.4 9.5 14.6 14.8 16.1 12.8 16.3 22.7 31.0 39.0 18.8 9.8 13.1 10.8 13.0 21.7 16.9 53.5 26.0 59.7 13.7 16.3 25.0 22.4 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 11.7 10.2 7.1 6.6 7.4 8.4 11.3 9.0 8.0 11.3 8.1 11.6 11.8 9.4 10.4 10.3 9.9 8.0 25.3 6.7 7.7 16.7 18.8 5.6 7.0 8.5 8.2 12.0 9.5 18.9 5.4 8.4 8.5 6.6 12.5 10.9 12.7 9.7 32.0 5.9 11.2 12.3 8.3 8.7 9.1 2.9 7.3 8.9 10.5 33.4 7.6 8.2 6.6 9.8 25.0 11.9 9.8 28.6 11.8 18.1 0.0 9.9 14.6 12.3 32.4 8.7 13.9 0.0 38.9 17.6 28.2 13.4 21.2 9.7 13.9 10.3 14.3 11.3 19.5 10.2 16.4 10.5 7.6 19.5 20.0 13.6 20.8 18.2 19.5 15.5 15.8 9.0 20.5 9.3 12.8 11.8 3.0 21.6 0.1 12.7 15.5 9.4 15.0 8.5 9.2 13.7 9.3 0.5 11.2 10.5 10.6 11.9 16.5 10.3 9.7 20.4 12.4 11.0 12.6 9.6 12.4 16.4 9.6 3.4 12.6 14.7 4.6 14.9 3.5 8.1 5.0 3.9 13.1 10.6 6.5 5.7 18.2 6.2 21.5 6.1 5.5 5.8 7.1 7.4 9.0 8.0 6.7 7.7 8.5 8.2 8.5 8.3 7.3 9.8 6.7 0.0 2.3 27.1 10.1 5.2 12.1 14.4 9.6 4.0 5.2 7.5 7.2 7.2 9.7 9.2 0.0 8.8 6.5 7.9 23.5 10.7 0.0 6.8 7.4 6.2 6.1 14.3 22.2 7.6 6.8 10.2 9.2 7.3 10.1 8.1 4.2 12.0 12.4 0.0 29.5 7.3 4.1 16.1 10.4 0.5 8.4 12.1 12.4 51.5 13.1 7.6 10.3 47.7 25.5 8.5 7.3 5.7 5.6 4.3 17.4 17.0 9.5 5.4 0.0 5.9 9.5 0.3 2.5 7.6 4.1 6.7 8.0 10.5 6.5 11.0 TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.9;Extravillous trophoblasts: 33.2;Proximal tubular cells: 48.6;Theca cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017156: , HPA014589: AB_1858185, HPA048020: AB_2680234" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (5.01e-2)" "unprognostic (9.86e-2)" "unprognostic (1.21e-1)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "unprognostic (3.34e-2)" "unprognostic (6.98e-3)" 29.7 23.1 21.8 19.5 38.7 16.6 31.5 20.6 24.4 19.8 19.1 27.7 29.3 24.5 21.3 28.9 20.4 16.1 38.8 23.6 23.0 36.8 61.7 15.9 22.2 21.3 18.6 30.8 26.8 27.2 14.8 23.4 21.9 26.4 29.8 45.4 21.9 26.9 66.4 19.8 24.4 26.7 17.9 19.2 21.5 19.6 22.9 29.6 30.1 76.1 25.9 27.3 17.8 19.5 70.2 48.3 39.8 57.9 55.4 60.0 52.0 57.9 49.6 52.2 53.8 68.7 39.0 83.2 49.9 49.7 46.6 67.4 73.1 53.4 76.7 31.6 33.7 95.2 30.3 67.3 34.6 117.2 41.8 53.7 48.6 46.5 75.6 46.5 38.8 40.1 69.2 65.6 63.3 51.9 79.6 47.5 55.2 107.4 101.2 72.0 80.9 89.0 42.6 52.2 72.2 60.1 42.3 67.0 77.9 38.2 87.1 65.8 35.2 45.5 60.3 25.8 44.0 71.1 108.8 139.1 44.1 70.0 35.2 1.1 1.0 1.2 1.9 1.1 2.3 2.0 2.3 2.0 1.4 1.4 2.3 2.5 0.2 2.7 1.3 1.4 1.0 0.8 21.8 38.7 20.6 24.4 23.6 23.0 21.3 18.6 21.9 17.9 22.9 19.5 24.2 6.4 25.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 30.0 20.2 0.0 0.0 11.2 14.7 0.0 26.8 11.5 0.0 11.7 19.0 0.0 13.8 34.9 10.0 0.0 0.0 0.0 20.1 33.2 12.9 0.0 25.4 7.6 27.1 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 2.3 0.0 0.0 48.6 10.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 16.3 6.3 32.9 0.0 0.0 TRAPPC13 "C5orf44, FLJ13611, MGC48585" ENSG00000113597 "Trafficking protein particle complex 13" A5PLN9 5 65625004-65666233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037777 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA037777: AB_10672464" "unprognostic (3.66e-2)" "unprognostic (3.27e-1)" "unprognostic (1.54e-2)" "unprognostic (7.22e-2)" "unprognostic (4.79e-2)" "unprognostic (1.16e-2)" "unprognostic (2.55e-2)" "unprognostic (2.49e-2)" "unprognostic (5.70e-2)" "unprognostic (5.75e-2)" "unprognostic (3.49e-2)" "unprognostic (1.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (2.89e-1)" "unprognostic (2.58e-2)" "unprognostic (2.53e-2)" "unprognostic (6.25e-2)" 10.0 11.5 7.8 8.9 8.4 8.0 12.8 9.1 9.9 10.6 7.0 10.8 9.3 10.8 9.1 12.4 8.9 9.3 16.8 8.3 9.4 20.0 14.7 10.5 10.8 8.7 8.8 7.6 7.3 22.7 8.8 10.4 8.8 18.7 13.3 16.6 9.1 10.9 13.4 5.8 9.1 12.9 9.1 9.9 10.0 10.6 8.7 16.6 17.3 16.8 10.8 12.1 7.0 10.4 20.7 13.6 21.0 38.2 15.8 20.2 20.7 23.8 21.2 29.1 31.2 11.8 28.7 21.3 25.5 19.5 31.0 18.8 24.0 25.0 33.9 14.6 17.8 13.4 15.3 11.1 21.7 16.6 19.3 14.5 19.2 22.7 28.8 17.5 25.8 30.0 16.2 19.1 26.3 21.9 27.3 6.4 9.5 11.9 7.4 23.7 26.9 24.0 20.8 23.2 25.4 19.2 29.3 17.4 22.2 11.6 25.7 20.8 17.8 10.2 14.0 22.6 24.4 12.6 26.3 34.0 21.3 28.9 19.8 17.6 8.3 3.6 8.4 9.3 11.0 5.8 8.1 7.0 9.0 4.7 7.9 7.9 3.1 8.9 13.4 6.7 9.3 9.1 7.8 8.4 9.1 9.9 8.3 9.4 8.7 8.8 8.8 9.1 8.7 10.4 10.4 19.2 10.5 27.1 7.4 5.7 6.8 17.3 6.2 13.3 8.5 5.5 7.1 12.8 13.1 7.3 10.4 12.1 13.0 7.6 15.6 12.9 24.6 7.9 7.6 11.9 15.5 12.0 54.7 10.8 9.6 9.1 11.2 7.6 3.8 9.8 8.2 11.2 12.4 13.5 44.2 8.9 26.4 13.9 7.7 10.2 7.5 9.6 7.2 28.1 11.1 14.8 11.3 46.3 66.5 10.3 6.3 13.2 8.9 11.8 11.0 25.2 13.4 16.2 6.6 8.7 8.3 16.4 8.6 9.1 6.8 15.2 12.0 10.2 8.7 11.9 TRAPPC3 BET3 ENSG00000054116 "Trafficking protein particle complex 3" O43617 1 36136570-36156053 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028408 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus" "HPA028408: AB_10601826" "unprognostic (3.54e-3)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (4.94e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.70e-6)" "unprognostic (7.39e-3)" "unprognostic (1.15e-1)" "unprognostic (7.12e-3)" "unprognostic (7.38e-2)" "unprognostic (2.94e-1)" "unprognostic (9.25e-3)" "unprognostic (2.61e-2)" "unprognostic (9.47e-2)" "unprognostic (2.10e-3)" "unprognostic (6.53e-2)" 43.7 74.7 42.5 31.2 43.0 28.8 46.6 47.0 50.7 38.5 53.7 57.0 33.6 41.1 60.7 61.6 37.0 32.6 51.1 43.1 44.9 55.3 51.2 36.4 38.3 48.0 45.1 28.2 46.0 54.4 47.0 37.8 47.2 39.2 42.5 39.9 46.4 45.4 48.9 51.5 38.5 49.9 48.3 41.6 48.2 53.1 46.3 51.3 59.9 44.6 54.4 46.2 41.2 48.9 95.7 65.6 44.9 70.2 114.2 91.4 87.9 85.2 109.0 100.0 97.0 55.9 90.0 40.4 79.0 95.0 79.6 68.8 69.9 114.1 113.8 79.8 103.7 75.8 77.2 81.7 132.6 80.0 76.7 78.3 98.5 93.8 91.5 103.6 126.7 101.2 93.2 67.0 122.0 71.4 95.6 74.6 60.5 79.5 93.7 65.8 63.8 90.9 128.4 76.1 67.8 49.7 69.2 78.5 140.1 115.2 50.2 59.6 95.6 59.1 66.7 116.0 116.3 80.1 87.0 67.3 100.7 88.7 60.5 161.9 130.2 148.7 85.0 142.5 89.4 93.6 100.4 90.4 132.6 89.0 96.0 86.9 134.3 95.8 116.3 109.4 135.4 155.3 42.5 43.0 47.0 50.7 43.1 44.9 48.0 45.1 47.2 48.3 46.3 48.9 41.9 25.6 27.6 12.1 45.6 101.1 111.5 152.1 52.3 41.8 97.8 78.5 57.8 55.8 75.7 38.6 16.7 145.7 43.0 55.1 170.2 157.0 286.1 51.8 38.3 59.1 48.3 63.3 15.4 188.5 146.0 52.1 29.0 55.6 45.7 40.5 33.2 49.8 145.0 53.8 16.9 51.2 132.2 56.1 74.7 131.0 42.9 60.6 96.0 10.3 104.4 68.0 61.8 8.5 17.9 178.4 72.1 51.9 80.7 196.9 73.3 115.9 49.2 30.7 32.9 37.4 69.2 172.5 89.4 63.4 123.6 191.4 50.4 50.3 54.3 134.1 TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561868-101566446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria Nucleoplasm "HPA036671: AB_10602085" "unprognostic (7.42e-2)" "unprognostic (2.68e-1)" "unprognostic (9.08e-3)" "unprognostic (4.47e-3)" "unprognostic (5.01e-2)" "unprognostic (5.55e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (5.42e-2)" "unprognostic (4.70e-2)" "unprognostic (3.28e-2)" "prognostic favorable (3.32e-5)" "unprognostic (2.77e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" 16.6 17.4 6.9 14.8 7.9 18.2 20.8 9.1 9.7 12.2 8.5 15.4 12.7 14.1 13.4 18.9 14.5 11.4 21.6 7.8 7.9 19.2 25.2 10.3 20.5 7.4 7.4 15.7 10.4 15.6 6.4 14.0 7.9 11.9 14.7 7.8 13.0 9.9 27.6 12.7 13.1 16.0 7.4 12.5 12.1 11.8 7.5 17.5 15.4 30.2 20.7 26.6 8.6 7.5 58.9 28.2 36.6 37.1 33.0 28.0 34.1 34.2 33.3 43.6 48.5 43.2 38.6 121.3 43.4 21.6 35.4 57.9 71.5 52.5 59.7 43.8 35.3 81.6 20.5 31.6 25.4 72.5 33.1 32.9 53.3 38.3 35.4 23.2 43.1 45.4 70.3 26.3 47.6 40.4 58.2 52.9 68.2 75.9 60.4 42.9 29.8 54.3 56.2 49.0 90.9 51.8 26.7 56.0 78.1 31.9 74.0 78.9 28.7 23.6 45.0 15.8 36.5 30.4 59.4 117.5 40.0 51.5 36.2 56.6 18.2 12.8 21.1 24.7 29.8 35.7 26.2 25.1 22.7 34.2 35.0 33.2 8.1 21.4 27.4 25.8 26.2 19.5 6.9 7.9 9.1 9.7 7.8 7.9 7.4 7.4 7.9 7.4 7.5 7.5 33.3 22.4 24.0 4.9 47.9 94.3 153.4 106.8 63.7 30.6 39.9 52.7 51.5 21.5 69.2 29.5 14.6 65.7 50.3 21.5 52.8 48.5 49.7 54.7 54.0 39.5 35.8 65.0 8.8 33.8 47.0 38.8 28.1 63.5 46.3 47.3 31.4 56.9 31.1 21.9 8.5 31.5 69.2 27.3 31.9 13.7 37.3 23.7 14.2 1.9 42.1 29.8 37.0 6.6 7.6 37.2 17.9 37.6 21.5 85.3 17.3 72.0 53.3 33.9 32.9 58.1 41.3 77.7 55.0 55.2 105.0 65.5 46.4 57.1 47.0 127.4 TRMT2B "CXorf34, FLJ12687" ENSG00000188917 "TRNA methyltransferase 2 homolog B" Q96GJ1 X 101009346-101052116 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003745, HPA035120, HPA040814" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies" "HPA003745: AB_2667047, HPA035120: AB_10601702, HPA040814: " "prognostic unfavorable (1.58e-5)" "unprognostic (6.72e-3)" "unprognostic (3.28e-1)" "unprognostic (1.54e-2)" "unprognostic (4.44e-1)" "unprognostic (8.74e-2)" "unprognostic (3.52e-2)" "unprognostic (8.16e-3)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (8.80e-2)" "unprognostic (2.78e-2)" "prognostic favorable (2.30e-7)" "unprognostic (4.58e-2)" "unprognostic (4.82e-1)" "unprognostic (5.03e-2)" "unprognostic (1.60e-2)" 5.4 6.4 3.3 7.1 3.3 7.8 6.3 3.7 4.0 6.8 5.6 7.8 6.1 4.7 4.0 8.2 5.3 5.4 9.1 3.3 3.8 8.7 6.2 6.5 10.3 4.3 3.9 6.7 6.4 14.7 5.8 3.9 4.7 6.6 9.2 2.4 9.9 5.3 15.0 6.9 9.2 5.0 3.4 10.6 8.7 2.5 4.0 14.7 8.6 14.4 11.3 5.2 6.1 3.3 22.4 18.9 3.8 8.9 8.7 4.5 11.6 11.4 15.4 12.6 18.7 20.6 17.5 19.9 22.3 10.6 25.6 13.7 17.5 16.0 15.7 17.2 10.9 12.6 15.6 9.9 7.6 22.5 19.6 5.8 9.3 18.2 8.4 8.8 24.8 21.2 13.0 18.3 11.7 22.5 28.5 11.6 5.2 27.7 14.0 22.8 18.2 19.1 9.2 12.8 5.5 7.4 19.4 14.0 11.7 10.4 9.1 10.8 14.5 15.7 9.4 14.8 10.3 11.5 18.7 18.1 12.2 25.3 12.4 14.9 10.0 18.8 15.8 8.0 17.0 18.7 18.6 15.8 9.3 20.4 21.8 18.3 5.7 18.7 9.5 10.0 16.8 14.8 3.3 3.3 3.7 4.0 3.3 3.8 4.3 3.9 4.7 3.4 4.0 3.3 3.0 6.4 6.3 22.2 10.5 2.3 5.5 4.1 6.2 0.8 3.0 1.5 10.3 1.5 5.0 14.7 2.1 6.1 5.7 5.4 7.9 4.0 0.1 3.3 1.9 4.0 6.7 5.7 17.2 3.4 3.0 3.4 6.1 2.9 13.3 6.9 3.6 4.1 3.6 1.7 18.5 6.8 2.0 5.3 0.6 0.8 3.4 3.4 1.8 18.7 5.6 4.8 14.4 9.5 11.6 5.3 4.8 3.8 4.2 3.8 5.5 5.7 6.0 1.8 0.0 5.3 3.0 0.2 3.8 6.2 1.6 5.1 8.7 4.4 6.1 5.3 TSFM "EF-TS, EF-Tsmt" ENSG00000123297 "Ts translation elongation factor, mitochondrial" P43897 12 57782761-57808071 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "RH-30: 962.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006204 Supported Nucleoplasm,Mitochondria NA NA 9200 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA006204: AB_1080405" "unprognostic (1.17e-1)" "unprognostic (6.84e-3)" "unprognostic (1.93e-2)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (2.56e-3)" "unprognostic (2.49e-2)" "unprognostic (1.53e-1)" "unprognostic (8.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.49e-1)" "unprognostic (1.49e-3)" "prognostic favorable (8.82e-4)" "unprognostic (3.05e-1)" "unprognostic (6.97e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" 23.1 57.6 17.7 23.5 18.5 26.1 26.3 18.8 20.9 16.7 21.1 28.9 27.4 15.0 17.4 22.3 18.0 13.9 43.6 18.8 19.0 39.2 45.2 15.1 24.2 18.4 18.3 13.5 17.1 35.0 16.5 16.5 19.7 16.6 26.8 16.7 20.0 16.4 58.6 21.6 21.0 17.5 19.0 17.4 19.7 25.2 18.9 22.5 16.2 64.3 20.7 24.4 15.7 18.7 56.3 63.1 35.5 52.5 33.7 33.9 53.2 46.4 39.8 71.6 50.2 74.1 71.6 142.6 85.8 38.9 39.1 64.9 60.1 66.2 51.3 57.7 78.0 82.6 51.9 64.7 50.5 112.7 47.2 39.6 65.3 55.6 25.4 52.2 44.7 75.7 110.3 70.0 56.3 64.8 64.8 113.0 57.5 81.7 83.7 78.3 962.0 125.5 70.5 64.1 80.0 49.1 47.7 84.8 83.6 31.5 148.9 71.7 33.1 39.6 54.6 58.9 49.1 52.0 120.2 108.7 53.6 63.7 48.1 8.5 24.6 15.3 28.0 23.7 36.0 28.5 30.9 28.3 30.3 26.9 31.1 31.7 6.5 33.6 30.5 23.4 30.9 26.9 17.7 18.5 18.8 20.9 18.8 19.0 18.4 18.3 19.7 19.0 18.9 18.7 16.5 19.2 10.8 6.2 18.5 25.9 14.5 57.4 10.8 19.4 24.6 21.1 31.8 27.1 28.7 46.0 14.6 68.5 23.5 13.2 95.9 66.0 73.3 19.5 19.7 18.7 13.8 20.0 8.4 87.6 52.3 18.8 13.3 16.3 22.2 31.0 16.4 38.3 35.4 15.2 8.5 20.9 36.7 11.4 13.9 42.5 22.7 18.1 26.6 10.3 66.6 23.1 12.3 9.5 8.4 47.2 15.7 24.0 17.5 21.3 19.9 146.2 26.0 20.1 59.2 19.7 31.6 46.1 65.8 21.1 36.2 47.6 18.6 71.1 35.3 13.9 TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoli, Plasma membrane" "CAB004283: AB_671392, HPA006161: AB_1080408" "unprognostic (1.42e-1)" "unprognostic (7.91e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-3)" "prognostic unfavorable (3.74e-6)" "unprognostic (5.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-2)" "unprognostic (4.15e-3)" "unprognostic (4.27e-2)" "prognostic favorable (5.52e-6)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" 40.4 55.6 41.1 32.2 42.2 60.8 56.6 43.1 50.8 44.8 45.7 49.5 42.8 40.2 56.3 56.7 49.3 36.5 68.2 42.1 44.5 70.1 62.3 43.9 42.9 42.4 42.3 44.6 45.4 61.5 36.5 61.4 42.4 43.1 59.0 43.6 46.4 41.1 77.1 47.2 43.4 42.9 43.9 34.0 45.4 55.5 41.8 45.9 52.4 83.0 57.4 46.9 42.2 46.5 51.3 79.1 73.7 51.1 82.2 85.4 63.7 77.1 103.0 92.2 90.3 54.3 27.5 65.5 49.2 86.4 103.7 77.0 74.0 70.3 102.0 95.4 87.7 41.1 38.6 79.7 106.3 64.6 69.8 75.0 139.9 48.6 131.6 102.2 76.8 68.4 66.9 55.2 112.7 85.7 45.7 66.8 45.1 115.6 81.5 37.0 72.5 54.7 63.6 68.8 52.2 88.6 75.7 61.6 101.1 77.1 59.7 64.8 43.1 63.0 38.0 126.4 59.4 37.2 76.0 56.9 64.5 34.2 80.5 187.8 69.8 155.7 50.4 81.6 52.4 78.5 48.0 54.0 66.1 69.2 51.5 54.9 123.6 57.9 114.3 54.5 84.4 91.1 41.1 42.2 43.1 50.8 42.1 44.5 42.4 42.3 42.4 43.9 41.8 46.5 63.0 64.1 57.5 22.9 44.4 42.6 81.5 159.2 26.7 41.0 39.2 42.2 68.0 42.9 90.4 44.1 25.0 191.9 34.2 85.5 125.2 112.4 48.0 58.4 36.0 54.4 61.6 74.5 29.1 101.3 107.7 48.6 32.6 48.9 44.9 46.2 47.2 36.0 79.6 37.0 28.4 65.0 156.6 45.2 33.6 21.2 56.2 51.6 56.9 26.2 82.3 86.1 54.6 32.2 32.8 132.7 76.2 43.2 47.0 103.0 72.2 126.8 113.4 43.3 46.0 44.7 81.2 177.6 153.7 32.8 48.4 296.1 38.1 91.5 47.8 97.4 TSNAX "C3PO, TRAX" ENSG00000116918 "Translin associated factor X" Q99598 1 231528541-231566524 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 194.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024613, HPA031054, HPA031055, CAB034263" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 36000 "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Golgi apparatus, Cytosol" "CAB034263: AB_2272293, HPA024613: , HPA031054: AB_10600415, HPA031055: AB_10602314" "unprognostic (6.28e-3)" "unprognostic (5.48e-2)" "unprognostic (1.62e-1)" "unprognostic (1.12e-1)" "unprognostic (5.55e-2)" "unprognostic (2.27e-1)" "unprognostic (2.96e-2)" "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-3)" "unprognostic (4.51e-2)" "unprognostic (1.91e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-2)" "unprognostic (6.52e-3)" "unprognostic (2.70e-2)" 22.7 31.9 12.2 20.2 12.8 15.1 25.4 11.5 15.1 19.5 17.8 18.4 17.7 21.5 22.8 19.4 18.0 18.7 26.2 13.2 15.2 31.7 26.0 20.8 26.4 11.9 12.7 18.3 16.3 40.0 17.0 20.4 12.3 22.8 19.6 19.9 18.1 20.5 50.5 21.8 17.3 20.7 13.4 28.5 17.7 20.9 13.2 26.6 29.8 40.7 25.7 19.9 14.9 13.7 30.3 24.1 36.7 29.7 27.1 32.6 41.4 33.1 50.9 42.2 36.0 21.4 40.8 42.3 55.0 38.0 15.7 31.9 29.3 31.4 53.9 38.4 51.7 40.7 23.9 28.6 35.8 67.8 82.1 40.4 32.4 40.9 32.3 26.4 30.7 31.6 66.6 28.8 58.0 12.9 44.0 32.9 53.4 26.5 28.3 42.8 39.8 56.8 46.9 33.9 34.1 65.7 35.3 43.3 116.8 14.5 63.2 113.0 28.9 28.3 26.3 57.6 61.0 48.2 68.9 46.4 46.8 52.0 79.7 194.4 34.8 85.6 30.6 40.2 30.3 28.5 33.5 30.6 33.2 28.3 34.6 34.0 37.7 51.9 55.7 22.3 39.4 33.6 12.2 12.8 11.5 15.1 13.2 15.2 11.9 12.7 12.3 13.4 13.2 13.7 48.3 28.9 41.3 0.0 25.5 43.8 21.4 42.4 8.6 59.2 27.2 20.1 24.1 40.0 25.3 42.3 29.2 44.4 36.9 21.8 54.8 30.6 12.6 23.6 20.5 46.1 28.9 59.5 0.0 31.1 51.5 28.1 11.7 19.3 77.3 26.2 31.8 32.8 49.5 65.6 0.0 28.2 38.7 62.2 35.0 9.4 33.5 40.5 26.6 0.0 51.7 72.0 37.0 0.0 0.0 26.5 21.8 36.1 13.4 17.3 22.4 45.8 31.9 47.1 39.5 34.4 30.2 40.8 65.4 13.0 51.4 36.3 30.5 46.8 25.6 14.9 TSTD2 "C9orf97, PP4189" ENSG00000136925 "Thiosulfate sulfurtransferase like domain containing 2" Q5T7W7 9 97600080-97633368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022537, HPA024241, HPA064304" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA022537: AB_1845850, HPA024241: AB_1845851, HPA064304: AB_2685238" "unprognostic (7.24e-2)" "unprognostic (5.56e-2)" "unprognostic (1.88e-1)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-2)" "unprognostic (1.38e-1)" "unprognostic (7.07e-2)" "unprognostic (1.10e-1)" "unprognostic (1.23e-3)" "unprognostic (9.67e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.75e-4)" "unprognostic (2.21e-2)" "unprognostic (5.31e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" 5.9 5.6 3.4 5.3 4.2 2.5 8.1 4.0 5.1 8.5 3.5 7.0 4.7 8.2 7.4 6.1 7.3 7.1 9.9 3.2 4.1 8.0 9.5 7.3 6.5 3.7 4.3 7.3 10.3 10.1 4.6 7.6 4.1 7.6 7.3 10.3 6.7 8.2 9.1 6.0 4.3 8.6 4.2 6.1 6.2 8.0 4.2 8.9 10.4 12.9 8.1 7.5 3.8 5.5 13.6 10.7 17.3 11.3 11.1 9.2 15.1 8.7 10.7 12.0 12.3 10.9 4.7 14.4 4.1 11.6 14.5 19.0 15.3 9.3 13.3 10.0 6.7 10.1 12.6 8.8 14.4 15.0 13.3 12.3 15.4 11.8 21.0 11.2 9.5 15.0 18.0 10.7 10.6 7.6 17.7 8.2 13.5 17.8 10.6 14.5 24.9 7.7 8.9 6.6 12.3 9.7 11.3 8.0 10.4 13.4 6.1 8.3 9.8 11.1 10.1 12.5 10.0 15.8 21.2 7.5 8.8 7.3 7.7 4.3 2.9 3.9 4.4 5.0 7.3 4.1 4.3 5.4 4.8 4.5 4.8 4.7 1.0 8.6 4.0 2.0 2.6 3.9 3.4 4.2 4.0 5.1 3.2 4.1 3.7 4.3 4.1 4.2 4.2 5.5 11.4 19.2 15.3 23.8 11.7 1.7 4.3 5.7 7.4 27.8 11.1 9.9 17.5 11.5 16.9 1.8 25.0 7.6 12.3 11.1 17.6 8.7 17.9 11.3 17.2 7.8 19.2 12.4 26.0 7.5 3.9 11.3 10.2 10.6 20.8 8.5 5.0 13.4 5.3 21.9 31.5 5.3 4.1 5.4 3.1 9.6 8.1 5.9 5.4 15.0 6.5 13.0 7.2 36.7 36.4 9.2 6.5 10.5 9.5 5.2 4.5 8.9 16.2 23.9 19.7 13.9 9.4 18.8 24.8 7.6 4.1 10.9 9.3 7.6 6.3 3.8 TTC37 "KIAA0372, THES" ENSG00000198677 "Tetratricopeptide repeat domain 37" Q6PGP7 5 95461755-95554977 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037905 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037905: AB_10673034" "unprognostic (5.99e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.62e-4)" "unprognostic (8.48e-2)" "unprognostic (9.49e-2)" "unprognostic (5.39e-2)" "unprognostic (1.40e-2)" "unprognostic (2.18e-1)" "unprognostic (6.88e-2)" "unprognostic (5.97e-2)" "unprognostic (6.81e-3)" "unprognostic (2.51e-1)" "unprognostic (3.30e-3)" "unprognostic (6.88e-3)" "unprognostic (3.91e-1)" "unprognostic (3.98e-2)" "unprognostic (7.90e-3)" 23.6 24.2 10.6 17.9 13.1 10.5 25.7 21.4 15.4 23.8 14.8 20.2 21.4 22.8 19.7 19.9 16.9 18.4 24.3 12.3 11.7 27.5 23.2 17.1 20.5 15.0 12.2 22.6 26.7 46.1 20.2 25.9 15.9 27.2 22.1 21.8 20.7 21.4 34.5 32.7 19.2 22.2 12.7 19.4 26.2 7.8 13.3 25.8 26.2 30.9 21.5 17.0 16.7 18.5 33.1 34.6 43.0 14.9 70.3 94.9 38.2 61.8 49.6 39.3 58.6 37.1 23.6 58.0 39.7 59.0 41.0 31.7 54.5 74.5 65.4 34.0 44.6 39.1 68.8 24.6 60.1 25.7 27.1 63.6 37.3 50.1 69.5 60.3 63.0 19.0 31.2 37.1 75.1 19.0 33.5 20.6 24.3 15.1 28.2 28.1 60.0 61.5 43.2 25.7 53.5 41.8 50.8 24.8 57.0 35.7 38.8 21.7 87.4 53.3 30.5 42.5 47.9 35.4 48.3 53.0 54.0 36.9 70.0 6.1 6.4 2.4 10.1 7.8 12.2 10.3 9.8 8.5 8.1 10.0 10.0 10.6 0.2 9.3 8.0 16.2 9.7 4.4 10.6 13.1 21.4 15.4 12.3 11.7 15.0 12.2 15.9 12.7 13.3 18.5 51.4 76.9 56.1 68.6 38.5 19.5 20.4 26.5 8.6 57.8 33.2 31.8 84.9 25.8 40.9 27.6 50.1 32.5 52.0 22.4 15.6 41.5 2.4 44.8 70.9 39.9 32.5 20.2 146.8 40.5 41.8 43.4 42.8 57.3 41.1 64.6 32.9 36.0 26.9 58.9 130.6 34.3 16.2 28.8 16.7 4.3 62.4 32.2 8.8 68.4 55.4 21.0 41.2 99.5 145.0 38.1 20.2 64.7 41.1 19.0 32.2 30.7 38.2 33.6 39.5 55.1 39.5 10.5 10.0 30.9 32.8 19.8 34.8 52.3 34.2 18.2 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 69.7 114.6 69.6 67.1 74.2 75.1 65.8 78.9 78.1 59.4 93.3 101.5 104.4 64.9 34.7 105.2 73.6 46.6 177.8 68.1 75.3 107.3 145.1 58.3 69.2 73.1 77.4 61.4 114.2 117.1 55.4 47.6 74.1 57.7 86.1 35.8 88.9 59.7 224.4 76.0 83.9 53.6 72.9 66.2 106.1 73.3 77.0 59.9 62.7 221.5 79.3 67.1 62.9 74.3 176.2 323.1 102.4 216.2 144.9 131.4 208.7 125.8 144.4 194.9 183.0 351.3 189.4 390.5 228.5 126.4 112.4 337.6 244.2 242.9 116.2 155.4 370.8 151.7 254.8 433.6 171.7 273.8 134.8 169.9 188.1 211.9 208.7 126.8 235.2 213.0 339.0 150.3 144.4 355.0 262.3 266.3 231.8 213.9 196.9 361.8 187.3 569.6 169.3 168.4 178.8 219.6 110.0 388.5 180.2 84.6 231.5 217.6 150.1 115.9 136.4 146.7 196.6 229.8 253.6 172.2 148.6 336.8 157.1 94.6 155.8 72.3 103.1 153.6 115.3 100.6 97.2 108.7 199.3 98.8 91.7 95.3 32.4 97.2 119.2 123.1 140.1 185.6 69.6 74.2 78.9 78.1 68.1 75.3 73.1 77.4 74.1 72.9 77.0 74.3 108.2 70.5 76.7 29.4 144.6 168.1 262.5 322.0 158.2 102.4 165.1 139.2 134.4 190.1 182.6 176.6 87.6 333.1 113.2 260.0 334.6 230.2 381.8 116.1 92.5 111.3 148.5 148.1 17.5 289.8 299.2 111.2 153.4 79.6 105.9 170.6 108.5 247.1 253.8 74.0 19.9 230.5 217.7 167.5 146.4 669.0 109.3 128.6 138.7 14.0 167.5 140.6 88.6 28.6 30.3 199.7 215.3 111.7 264.9 245.3 330.7 451.9 237.3 116.3 85.5 105.5 129.1 205.7 177.4 230.1 156.0 287.0 120.2 288.2 418.7 277.6 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" 15.3 13.3 9.0 18.2 9.3 19.6 20.0 7.3 9.2 21.3 9.9 21.5 30.7 19.9 17.9 28.6 27.6 22.6 27.3 10.1 8.4 21.9 27.7 16.9 25.4 10.9 9.6 19.1 17.4 30.0 2.7 29.4 8.8 18.4 22.9 7.6 25.8 17.3 39.0 30.6 23.3 19.7 11.6 20.8 17.7 26.2 12.6 29.3 30.0 38.9 27.3 23.9 8.6 8.8 51.8 26.8 22.4 33.9 52.2 62.8 56.3 25.9 73.3 40.3 36.4 29.2 108.7 19.9 43.8 34.8 27.0 49.2 28.8 41.1 22.0 33.8 33.7 37.2 16.9 22.5 48.7 48.2 28.1 45.9 54.9 24.6 71.0 54.6 38.8 39.6 31.1 13.3 31.6 14.3 32.1 15.3 32.6 104.0 27.0 27.6 24.9 15.2 32.7 29.6 25.2 40.3 21.0 67.8 41.4 39.4 41.5 148.7 30.3 21.9 19.0 20.1 29.5 16.3 12.0 6.6 42.9 71.9 38.3 64.6 53.7 41.9 61.3 57.3 87.3 48.1 53.8 62.6 46.2 55.2 73.6 74.5 48.8 84.6 57.5 57.3 40.2 88.1 9.0 9.3 7.3 9.2 10.1 8.4 10.9 9.6 8.8 11.6 12.6 8.8 28.7 6.4 19.1 58.8 45.3 27.1 26.0 41.7 40.5 27.3 31.2 24.3 23.8 21.5 29.4 23.9 27.1 111.6 48.5 37.3 23.5 44.1 26.0 24.5 21.7 26.4 8.4 31.3 110.9 34.9 84.6 31.6 19.4 21.9 22.2 34.3 17.9 29.1 48.5 32.0 103.0 30.1 40.7 39.1 121.4 22.0 35.1 88.4 30.2 81.5 35.7 48.8 69.0 82.0 73.3 29.0 32.6 50.8 11.7 48.7 48.0 22.6 31.6 21.2 32.9 24.7 32.1 66.2 35.1 31.7 33.1 132.4 66.0 54.4 39.1 34.4 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698109-39782792 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 29.9 19.4 13.5 23.4 17.5 21.4 21.7 20.9 24.5 16.0 9.2 35.8 31.2 17.8 17.7 26.2 12.7 12.9 18.4 18.3 14.9 26.7 45.4 16.4 20.1 12.9 14.0 13.6 13.2 20.4 15.8 24.4 13.1 19.8 24.2 21.0 16.9 14.9 37.3 22.6 24.8 17.2 7.8 18.0 31.8 16.5 14.2 22.4 23.8 25.6 18.0 20.2 17.2 16.0 91.3 90.7 49.3 45.6 29.8 28.7 82.8 122.8 26.4 32.8 34.0 138.0 91.1 114.3 105.2 35.0 79.8 39.0 95.4 54.7 51.9 76.1 70.0 145.7 88.9 121.6 38.4 159.0 79.6 27.1 60.2 46.0 49.0 35.2 43.3 49.3 152.9 39.6 33.9 86.6 111.5 89.9 67.7 54.4 69.8 66.3 144.0 44.2 46.0 123.9 103.9 47.4 91.7 34.5 58.9 54.1 44.4 58.2 116.9 49.9 105.7 60.0 114.5 55.3 174.0 121.4 26.9 101.4 59.5 19.6 18.1 24.8 14.4 16.9 13.4 20.7 15.0 13.8 19.7 14.7 11.2 12.6 15.1 14.0 25.4 27.6 16.0 10.5 13.5 17.5 20.9 24.5 18.3 14.9 12.9 14.0 13.1 7.8 14.2 16.0 63.2 57.7 63.1 69.2 53.0 122.9 65.5 74.3 59.7 62.2 65.3 52.5 72.3 52.9 66.7 49.7 29.2 84.5 76.5 143.7 66.5 83.5 144.9 72.0 82.3 65.6 59.7 85.8 115.9 89.4 168.7 59.2 68.3 90.9 34.8 40.1 63.5 113.6 80.2 104.3 113.8 74.5 65.1 77.1 91.8 202.4 65.3 76.5 56.9 89.0 104.0 87.1 56.7 87.0 118.2 139.6 94.3 56.4 55.5 111.4 75.3 98.0 60.7 42.9 39.5 61.8 121.1 145.2 55.1 74.3 137.9 147.5 61.3 54.8 74.1 107.0 UBE2V1 "CROC-1, CROC1, UBE2V, UEV-1, UEV1A" ENSG00000244687 "Ubiquitin conjugating enzyme E2 V1" Q13404 20 50081124-50115959 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 74.0;Erythroid cells: 80.1;Plasma cells: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Enhanced Nucleoplasm NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA052535: AB_2681863, HPA053186: AB_2682073" "unprognostic (1.39e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (1.01e-3)" "unprognostic (2.16e-1)" "unprognostic (2.00e-2)" "unprognostic (2.81e-3)" "unprognostic (4.35e-2)" "unprognostic (3.48e-2)" "unprognostic (5.32e-2)" "unprognostic (2.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (4.58e-5)" "unprognostic (2.58e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" 61.2 57.8 50.1 56.9 54.9 51.3 51.3 43.1 72.2 51.2 44.2 70.7 58.4 45.4 53.2 71.9 46.6 48.0 66.7 55.8 48.8 58.9 78.2 59.3 68.4 45.2 44.5 44.2 64.7 61.1 37.4 66.3 46.3 53.5 61.2 47.2 55.6 55.0 87.9 65.9 51.9 73.5 38.3 55.5 56.7 40.9 48.9 60.8 49.9 70.8 89.1 67.8 53.6 48.6 155.0 94.1 174.3 104.8 141.6 238.7 97.3 172.6 168.0 356.3 169.9 466.6 112.8 148.8 155.9 223.8 155.1 134.5 129.5 235.4 307.1 105.0 81.2 146.0 66.2 212.2 125.9 178.3 113.2 192.4 140.4 176.1 115.1 199.6 243.5 120.4 185.2 88.4 200.9 102.7 162.9 143.8 121.9 204.5 164.7 89.0 196.8 136.4 248.7 109.9 101.8 123.2 174.4 301.0 136.7 173.2 115.0 161.2 215.1 196.5 182.3 165.7 140.8 85.7 118.5 119.0 213.9 92.2 139.4 120.7 162.3 146.5 219.9 161.5 221.9 149.2 178.9 210.7 165.3 134.1 180.3 197.2 55.8 233.6 147.9 130.4 189.5 351.7 50.1 54.9 43.1 72.2 55.8 48.8 45.2 44.5 46.3 38.3 48.9 48.6 18.9 51.3 30.9 0.0 39.1 5.9 5.0 18.4 74.0 4.6 10.6 7.9 9.2 7.2 36.3 11.0 6.2 6.4 24.6 10.7 23.5 11.5 19.1 36.3 32.0 18.4 10.2 80.1 0.0 11.3 5.7 21.2 38.2 36.1 36.6 4.8 16.8 14.5 7.0 0.0 0.0 5.2 8.2 17.8 5.9 19.8 7.8 29.6 8.8 0.0 18.4 3.0 12.3 0.0 0.0 16.1 15.4 4.9 79.4 2.8 7.7 27.2 47.8 5.4 6.6 6.9 14.8 12.9 6.7 67.8 8.5 7.1 41.1 5.4 4.9 5.1 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 13.8 16.5 14.4 10.7 16.1 9.2 13.7 13.3 15.6 14.4 16.5 17.8 12.9 14.1 13.4 18.6 16.2 12.1 26.2 14.4 12.4 16.7 16.0 13.6 12.6 13.7 14.6 15.8 14.3 22.6 13.6 13.1 14.8 15.4 18.1 14.9 14.4 14.1 34.0 19.2 15.8 14.7 12.5 15.8 16.5 12.9 16.1 12.6 18.2 29.7 13.5 17.0 14.5 20.3 17.1 26.4 20.4 14.8 33.9 27.1 17.9 22.1 25.1 26.2 17.4 28.0 17.1 10.6 16.0 36.3 22.5 21.5 20.9 28.3 25.1 23.4 14.7 20.3 17.6 25.5 21.7 16.7 16.2 31.0 25.8 25.4 30.2 39.5 28.7 24.8 22.7 9.7 30.2 26.6 11.5 24.2 21.0 19.1 31.6 18.8 19.2 20.9 22.4 30.2 19.1 34.9 25.8 34.6 17.3 23.7 35.3 17.6 26.5 32.3 9.2 16.8 16.0 21.8 19.4 18.6 32.1 13.7 27.4 22.9 12.9 12.8 12.6 14.5 12.4 13.6 12.1 9.0 12.4 10.0 10.0 13.3 16.1 13.1 12.0 11.4 16.2 10.7 14.4 16.1 13.3 15.6 14.4 12.4 13.7 14.6 14.8 12.5 16.1 20.3 11.9 12.8 15.1 34.0 9.7 5.1 11.8 13.9 6.8 19.3 14.4 12.8 35.4 11.5 17.1 16.5 33.3 17.9 12.8 21.0 11.7 17.7 15.7 12.6 12.5 14.2 9.0 13.0 24.5 15.3 11.5 11.1 18.8 12.2 9.5 20.0 11.7 18.8 12.5 21.9 23.6 15.9 18.3 19.2 6.1 32.0 12.5 14.2 10.6 13.1 17.7 13.6 32.0 21.1 38.3 25.3 13.7 9.8 15.6 17.2 19.6 19.9 18.4 25.0 6.6 9.4 13.0 10.4 13.2 13.4 7.2 23.7 10.7 17.7 16.8 18.4 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 25.7 17.4 12.0 21.5 13.2 16.2 21.7 17.5 14.1 18.4 18.8 22.3 20.0 19.4 13.4 28.3 18.5 19.1 28.5 13.2 14.1 20.3 22.9 19.0 20.9 14.6 13.4 20.0 22.4 36.2 11.1 17.5 14.9 19.9 23.2 20.2 22.7 22.7 65.6 20.8 20.8 29.2 12.7 18.0 20.9 26.2 14.8 18.6 17.3 58.5 22.8 28.1 17.0 15.0 68.8 53.3 33.5 67.3 58.8 61.3 37.1 74.0 63.4 61.1 61.3 48.3 55.7 36.8 64.0 82.1 79.6 42.4 52.6 68.3 72.0 67.6 48.3 37.6 35.6 35.0 58.4 56.9 52.8 54.8 61.6 68.0 55.9 46.4 72.2 30.3 55.7 39.9 87.6 59.8 56.2 35.9 53.3 61.1 63.6 31.9 37.7 75.9 63.2 74.1 53.5 55.2 72.8 61.9 54.5 37.2 32.0 39.3 65.3 76.6 16.5 190.0 93.3 39.7 42.9 37.0 87.7 83.0 89.5 0.3 1.8 1.1 2.2 2.3 3.0 1.1 2.4 2.4 2.0 1.2 2.2 2.7 0.6 2.1 2.5 1.8 2.8 1.5 12.0 13.2 17.5 14.1 13.2 14.1 14.6 13.4 14.9 12.7 14.8 15.0 23.8 22.4 19.7 52.2 14.2 27.5 17.3 19.0 17.6 34.7 22.4 16.9 33.7 22.8 14.2 25.8 66.7 14.9 25.3 27.3 9.8 20.3 11.6 21.6 27.4 23.4 24.5 14.9 98.9 17.7 17.4 19.6 27.0 24.5 9.5 23.0 23.6 48.3 15.4 32.0 100.7 21.8 12.2 27.6 15.2 10.1 15.5 20.6 5.4 52.5 22.0 9.9 26.8 81.4 96.2 27.5 13.4 25.6 17.5 31.5 20.6 19.1 19.8 39.9 0.0 23.1 21.4 26.6 27.3 37.5 33.2 15.1 20.9 22.3 26.2 28.1 UBXN2A UBXD4 ENSG00000173960 "UBX domain protein 2A" P68543 2 23927285-24004909 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065482, HPA069096" Supported Approved Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 51: Myeloid cells - Hemostasis" Centrosome "HPA065482: AB_2685495, HPA069096: AB_2686084" "unprognostic (5.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.14e-1)" "unprognostic (8.86e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (9.26e-2)" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (1.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-1)" "unprognostic (8.85e-2)" "unprognostic (2.14e-1)" "unprognostic (4.60e-2)" "unprognostic (6.75e-2)" 6.1 3.7 3.5 3.4 4.1 5.0 5.0 5.9 3.6 3.1 2.6 4.9 5.7 5.1 3.9 5.1 3.5 3.7 7.8 2.9 3.9 4.1 5.7 4.6 3.9 4.2 4.5 3.9 3.0 7.4 1.5 5.3 4.2 3.8 4.1 5.6 4.5 4.7 10.9 4.8 5.4 6.9 3.9 3.0 2.9 3.2 3.9 4.5 3.9 7.9 4.3 4.0 2.4 5.8 14.8 9.6 13.1 8.8 14.8 12.9 6.6 14.8 9.9 14.1 9.8 7.2 6.5 12.7 4.5 9.5 9.9 6.2 12.7 10.5 12.5 25.7 12.0 14.9 6.4 10.9 10.9 9.5 6.4 15.8 8.3 12.4 9.4 10.0 8.5 9.6 17.0 12.3 12.4 11.2 12.6 6.0 10.4 9.5 6.8 16.9 32.7 5.6 5.9 11.3 6.5 15.6 14.2 6.9 18.6 9.2 4.1 5.3 14.2 10.1 10.5 9.3 9.6 17.7 20.3 18.0 7.9 8.7 10.4 4.8 2.1 2.5 3.2 1.2 3.5 3.7 3.3 3.1 1.7 2.9 3.6 3.3 1.9 4.7 1.6 4.1 2.7 1.6 3.5 4.1 5.9 3.6 2.9 3.9 4.2 4.5 4.2 3.9 3.9 5.8 26.9 25.6 19.2 27.1 29.3 25.5 26.9 13.6 35.9 17.1 29.7 35.2 54.9 15.7 13.6 16.5 43.8 33.9 38.9 23.1 17.6 27.4 2.3 28.9 38.7 23.5 4.2 19.6 22.0 27.2 34.4 33.4 26.5 30.6 17.7 25.2 25.4 16.3 15.6 42.1 35.5 18.3 18.3 15.4 17.5 2.9 26.4 28.2 35.6 13.1 26.7 25.6 27.8 26.7 53.6 38.4 29.9 26.7 28.7 32.8 32.3 17.7 14.7 28.4 32.9 27.6 34.7 25.0 15.6 27.5 31.3 37.4 29.0 10.2 19.5 36.3 UCHL5 "CGI-70, INO80R, UCH37" ENSG00000116750 "Ubiquitin C-terminal hydrolase L5" Q9Y5K5 1 193012250-193060080 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005908, HPA006069" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 18000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA005908: AB_1858585, HPA006069: " "unprognostic (3.66e-2)" "unprognostic (3.84e-3)" "unprognostic (5.17e-2)" "unprognostic (5.98e-2)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (7.41e-2)" "unprognostic (1.96e-2)" "unprognostic (1.04e-3)" "unprognostic (3.44e-3)" "unprognostic (6.92e-2)" "unprognostic (6.41e-3)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (4.33e-2)" 19.9 19.0 11.0 22.5 12.1 24.6 22.7 20.3 15.8 13.6 5.5 23.3 24.7 14.8 17.5 32.2 11.3 15.5 30.5 13.3 12.3 27.2 37.9 15.9 29.1 11.8 11.5 16.4 33.1 20.3 9.7 23.1 12.8 21.4 24.0 37.7 26.0 16.0 39.7 21.3 24.2 18.1 12.9 18.0 17.8 13.4 10.7 24.8 19.2 36.8 32.6 19.1 14.3 14.1 136.6 74.0 61.7 65.5 37.1 37.8 76.4 80.1 40.4 74.8 65.8 71.4 94.9 104.7 72.5 44.4 43.2 85.5 84.1 99.5 100.9 110.0 61.9 126.0 97.5 97.3 57.6 198.5 67.8 33.9 44.5 106.1 91.2 33.6 76.4 100.3 285.1 86.2 67.3 105.9 146.2 70.1 57.7 89.1 46.9 84.5 68.3 216.4 70.8 81.0 61.2 76.7 72.7 97.3 110.4 64.9 82.2 95.8 49.9 71.9 21.4 70.0 125.0 62.8 105.2 117.5 40.2 119.5 123.6 60.9 31.7 41.6 53.3 40.1 59.5 43.8 48.0 51.2 39.0 37.4 51.0 57.1 19.5 75.2 45.0 41.3 51.3 44.8 11.0 12.1 20.3 15.8 13.3 12.3 11.8 11.5 12.8 12.9 10.7 14.1 33.9 9.6 30.2 12.7 28.6 24.3 13.5 27.9 18.8 20.6 19.4 16.6 79.5 21.5 28.5 27.6 43.8 35.8 45.7 18.9 45.0 26.3 2.8 13.0 15.4 21.4 10.8 39.7 35.4 28.3 34.5 22.8 20.9 16.0 56.3 21.4 17.9 24.6 28.0 25.2 33.2 20.2 16.2 18.8 20.7 3.8 14.9 25.0 17.8 19.7 23.4 27.4 75.2 18.1 29.6 25.3 10.6 17.3 58.5 21.8 30.2 39.9 21.1 43.5 19.7 19.6 34.9 22.1 16.8 32.7 30.0 25.2 34.5 31.9 23.2 12.4 UFL1 "KIAA0776, Maxer, NLBP, RCAD" ENSG00000014123 "UFM1 specific ligase 1" O94874 6 96521595-96555276 "Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030558, HPA030559, HPA030560" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA030558: AB_10600663, HPA030559: AB_10600537, HPA030560: AB_10602000" "unprognostic (5.40e-2)" "unprognostic (7.48e-3)" "unprognostic (1.06e-2)" "unprognostic (1.99e-1)" "unprognostic (8.12e-2)" "unprognostic (9.04e-2)" "unprognostic (9.99e-2)" "unprognostic (4.67e-2)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (1.49e-1)" "unprognostic (1.50e-1)" "unprognostic (4.46e-2)" "unprognostic (4.10e-2)" "unprognostic (5.92e-2)" "unprognostic (8.65e-2)" "unprognostic (4.46e-1)" 17.0 20.6 9.8 18.9 13.1 17.9 21.4 11.9 15.4 20.8 7.8 18.7 22.7 19.0 23.4 20.7 16.8 18.0 23.7 9.2 12.1 21.3 29.7 15.4 22.1 13.8 11.4 22.4 25.2 24.9 10.0 18.1 15.3 24.4 19.5 31.6 23.5 17.9 21.1 20.3 22.8 17.1 12.4 17.9 21.8 14.2 10.8 20.8 28.1 21.4 21.8 20.1 11.2 19.5 16.9 8.8 18.3 30.7 25.8 39.2 27.2 23.3 23.6 14.6 13.6 11.0 19.2 40.7 28.9 23.5 16.2 32.0 15.0 22.0 21.3 21.9 13.6 17.9 13.3 20.2 34.3 34.0 25.6 28.2 20.1 17.4 47.9 27.1 24.2 25.7 24.1 43.7 27.9 16.3 12.5 21.0 6.6 14.5 9.9 15.6 21.4 32.6 26.5 30.5 12.9 12.5 19.2 22.4 21.5 16.2 54.4 28.7 24.0 20.3 11.0 20.8 24.7 25.7 14.2 30.9 31.2 22.5 19.0 8.7 7.9 8.9 8.7 10.1 10.0 9.6 9.2 9.4 10.2 8.6 11.4 9.3 1.6 13.1 10.4 10.7 11.1 7.2 9.8 13.1 11.9 15.4 9.2 12.1 13.8 11.4 15.3 12.4 10.8 19.5 42.8 57.7 50.2 54.2 53.9 19.5 34.4 52.2 36.5 48.8 33.3 33.8 60.4 31.5 64.9 46.0 45.9 64.1 57.2 31.6 19.6 42.0 61.0 64.3 60.8 35.1 19.8 30.7 26.5 50.7 34.3 45.2 32.1 62.2 30.9 43.0 32.5 69.5 35.4 43.7 33.0 48.9 36.7 33.2 13.9 44.1 50.1 37.5 14.2 30.9 42.5 34.9 39.1 58.3 103.1 40.4 29.9 50.4 72.7 29.8 46.1 30.7 76.1 74.9 19.7 49.0 44.2 85.3 37.8 37.6 19.2 91.0 46.5 59.5 35.9 29.8 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 556.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 158.8 117.7 69.0 103.1 71.2 127.7 108.4 75.5 90.0 90.8 113.9 259.8 292.5 98.2 72.7 157.4 109.7 99.5 559.4 72.4 73.7 240.0 245.1 75.4 120.0 74.1 69.5 114.5 89.7 257.2 39.8 96.5 72.7 95.6 262.8 142.3 133.8 104.3 722.2 85.4 233.6 121.2 65.8 80.9 153.2 55.8 76.5 131.3 107.9 933.2 149.3 153.6 59.8 73.3 173.9 193.1 116.5 66.4 154.3 186.8 169.1 163.8 160.6 177.5 174.5 347.9 177.7 338.9 144.3 170.4 129.8 324.6 222.3 212.7 193.7 151.4 178.4 185.9 166.1 494.3 164.6 249.1 501.2 232.3 229.4 130.3 186.2 169.4 248.1 224.1 217.9 159.1 177.2 230.6 288.6 175.0 124.6 261.1 148.8 310.9 263.6 390.0 285.8 214.6 154.4 114.9 237.2 318.6 190.3 151.6 354.4 264.1 179.3 103.3 98.1 104.0 148.0 126.3 87.2 302.7 188.7 239.8 126.4 80.1 128.7 71.4 80.0 147.8 103.3 96.0 98.3 89.3 153.9 77.9 106.8 97.6 45.9 101.8 148.1 67.6 134.8 157.3 69.0 71.2 75.5 90.0 72.4 73.7 74.1 69.5 72.7 65.8 76.5 73.3 105.5 64.1 52.5 81.9 81.1 90.6 190.8 444.0 74.6 109.1 91.7 79.6 556.2 84.4 194.9 71.7 87.6 238.3 82.6 233.4 455.9 124.5 88.0 72.0 55.7 91.3 113.8 92.4 65.0 109.6 157.6 89.0 144.3 65.8 92.6 99.6 84.3 122.3 195.5 69.0 74.0 224.4 238.0 145.1 100.6 89.9 68.3 104.6 131.6 27.2 162.1 108.0 91.6 60.3 50.7 97.2 214.0 97.0 72.9 114.4 378.0 306.9 110.2 152.6 78.9 94.1 109.5 68.9 56.7 132.0 88.4 278.3 91.3 170.2 358.7 204.3 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 231.6;tongue: 285.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1474.9;Distal tubular cells: 1035.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favorable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 28.7 50.1 25.6 17.4 26.7 52.8 24.7 29.4 31.1 18.3 33.6 49.0 43.2 19.2 23.1 33.2 19.3 13.2 138.3 27.2 28.4 62.5 50.9 17.6 17.2 27.0 27.4 15.4 29.4 47.3 19.9 17.3 26.1 18.8 52.6 26.6 26.7 21.9 231.6 27.9 34.0 24.8 26.4 21.1 39.3 25.9 29.3 26.0 16.8 285.9 25.9 25.7 20.3 26.0 63.0 103.7 37.7 34.1 60.6 45.9 41.8 47.8 49.7 64.7 71.1 63.3 37.7 56.7 49.2 54.4 52.7 64.8 83.4 56.9 77.6 38.7 83.2 80.2 39.2 58.1 51.3 77.2 67.5 55.5 60.4 44.2 66.9 38.0 52.4 69.0 58.0 34.5 70.2 58.0 54.5 57.6 39.6 132.2 39.7 48.9 50.3 43.1 80.9 74.4 45.8 22.4 43.5 84.9 58.2 42.0 39.6 63.4 33.4 43.5 66.4 30.2 50.4 16.4 33.3 52.5 38.4 66.4 31.7 51.4 90.7 43.8 50.0 90.9 50.3 54.8 53.2 51.9 106.6 48.0 56.1 53.6 27.3 49.2 78.3 59.3 68.4 166.2 25.6 26.7 29.4 31.1 27.2 28.4 27.0 27.4 26.1 26.4 29.3 26.0 69.7 54.5 46.6 16.6 104.9 147.6 279.7 466.7 105.9 71.8 119.5 128.4 1474.9 161.5 201.4 114.0 16.7 282.0 116.8 321.6 1035.0 245.2 258.4 106.1 66.8 106.8 160.0 147.9 18.1 235.1 271.7 126.7 139.7 88.5 90.7 114.2 83.9 272.1 266.1 52.2 19.2 293.6 317.3 160.6 109.6 146.0 92.2 136.6 165.4 13.1 206.6 124.6 132.8 19.6 15.8 205.0 225.8 81.6 159.4 257.3 338.6 758.4 132.4 84.1 98.6 107.5 131.0 348.8 80.5 203.9 160.3 381.9 109.5 209.1 407.4 372.1 USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699986-84779922 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 742.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 742.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "HPA006731: AB_1080495, HPA006749: AB_1080492" "unprognostic (4.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.36e-2)" "unprognostic (4.85e-2)" "unprognostic (6.93e-2)" "unprognostic (1.77e-3)" "unprognostic (1.03e-3)" "unprognostic (2.91e-3)" "unprognostic (1.75e-1)" "unprognostic (3.84e-2)" "unprognostic (2.56e-2)" "unprognostic (1.82e-3)" "prognostic favorable (1.00e-4)" "unprognostic (5.91e-2)" "unprognostic (4.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.38e-1)" 24.8 21.7 19.6 29.4 20.3 29.5 23.4 22.1 22.9 21.0 17.8 31.2 29.5 25.9 23.9 29.1 27.0 18.5 25.4 20.8 20.7 28.8 33.8 18.7 36.7 18.8 18.7 27.1 23.0 41.5 6.0 40.3 19.0 28.3 26.4 52.5 21.0 25.9 46.6 25.7 27.4 31.0 19.8 32.6 23.8 22.0 20.4 29.1 27.4 39.5 37.7 32.1 10.1 21.6 63.6 72.9 78.5 104.7 31.4 50.2 111.5 58.0 60.1 96.9 51.5 106.9 54.9 102.9 65.2 61.1 47.7 69.8 108.2 89.7 139.0 41.3 63.3 63.2 37.3 92.2 39.4 95.0 37.9 30.0 74.8 95.6 112.3 57.5 76.4 68.5 153.4 22.7 73.1 129.4 92.4 96.8 102.5 71.8 56.7 119.9 44.5 55.0 81.9 48.4 73.0 48.6 130.5 48.7 54.0 72.3 108.4 76.8 55.7 66.9 60.2 39.4 62.2 38.8 53.7 272.3 44.5 64.6 73.2 29.0 77.3 15.6 46.1 61.9 58.0 60.6 148.0 53.9 92.6 59.7 82.9 49.6 742.4 65.9 58.6 30.7 57.3 97.3 19.6 20.3 22.1 22.9 20.8 20.7 18.8 18.7 19.0 19.8 20.4 21.6 21.3 54.5 50.0 26.4 51.5 51.5 46.1 25.8 54.1 25.1 27.6 28.6 66.6 25.8 45.2 27.6 29.2 106.9 38.1 25.8 31.3 29.0 63.3 31.0 35.8 30.4 28.9 42.5 39.3 25.1 73.4 40.1 35.7 42.1 58.0 38.7 21.0 37.2 31.4 20.2 38.9 28.1 16.2 34.8 33.4 116.6 23.6 40.6 24.9 41.2 52.6 23.7 32.0 49.8 35.8 23.6 23.9 22.6 50.8 48.6 30.4 45.0 90.7 52.7 26.3 58.4 34.3 35.0 29.5 54.5 49.6 60.9 42.5 33.6 40.6 45.2 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9 X-linked" Q93008 X 41085445-41236579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA 24000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 16.4 16.8 11.9 14.3 13.9 18.2 14.2 12.7 12.8 15.3 14.3 14.8 13.6 15.4 14.9 14.1 16.0 13.0 15.3 14.3 13.2 17.8 33.9 14.4 15.8 12.2 13.1 13.4 16.0 30.0 10.2 18.4 13.8 12.3 13.7 22.0 11.5 15.3 39.1 13.8 14.3 16.3 12.5 13.3 13.8 17.5 12.8 18.8 19.5 28.4 16.2 15.0 12.6 16.4 38.6 44.2 39.1 40.2 33.0 32.7 8.8 21.5 28.8 23.8 27.5 21.1 16.9 25.7 11.5 48.5 71.3 25.3 67.1 39.7 39.7 32.0 50.5 29.3 41.3 19.9 27.6 26.4 21.0 29.3 17.9 56.4 53.4 35.5 37.2 17.1 36.0 20.3 38.6 29.1 18.8 12.7 42.6 14.1 24.7 20.3 51.8 16.9 24.7 30.7 22.2 20.8 89.0 26.7 26.0 69.8 24.3 16.2 40.2 36.6 27.6 34.6 24.0 19.1 22.3 30.9 26.4 12.1 18.5 1.7 2.3 3.0 2.5 1.9 3.6 2.8 3.0 2.7 2.6 2.1 3.0 2.8 6.4 2.5 2.5 2.1 2.8 1.5 11.9 13.9 12.7 12.8 14.3 13.2 12.2 13.1 13.8 12.5 12.8 16.4 38.1 41.7 35.1 48.0 42.6 48.3 30.8 29.6 55.2 38.1 41.3 29.5 83.5 54.3 37.9 27.6 37.5 39.6 46.3 58.5 7.9 28.4 14.9 85.5 56.9 43.6 26.9 41.0 84.9 26.5 25.4 41.4 41.8 136.9 25.9 58.3 45.7 62.8 32.6 37.0 86.0 39.1 18.3 47.8 42.1 15.4 33.2 55.5 33.8 67.5 44.6 31.3 30.9 74.9 108.0 32.6 40.1 49.2 38.8 35.6 47.7 21.5 35.8 31.2 32.9 70.6 48.3 86.4 82.9 55.2 55.3 46.7 42.4 45.8 38.0 40.2 VDAC2 ENSG00000165637 "Voltage dependent anion channel 2" P45880 10 75210154-75231448 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043475 Enhanced Supported Mitochondria NA NA 490000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA043475: AB_10795615" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (9.47e-2)" "unprognostic (9.00e-3)" "unprognostic (5.74e-2)" "prognostic unfavorable (4.51e-4)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.83e-3)" "unprognostic (5.89e-2)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (1.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (6.28e-2)" "unprognostic (1.34e-2)" 138.2 150.3 95.5 93.3 97.4 138.5 116.2 116.2 115.0 165.5 117.1 209.1 151.3 116.6 90.7 322.1 117.4 85.4 420.5 99.0 109.0 177.5 115.9 112.0 83.5 105.7 107.1 132.8 150.6 192.7 85.3 115.6 110.1 108.8 184.4 198.4 151.4 134.0 539.4 171.6 148.4 149.2 105.0 77.7 159.4 104.6 107.1 92.7 111.0 565.9 148.3 163.6 207.1 110.4 304.4 245.0 291.0 370.5 253.3 342.1 305.2 384.9 430.4 412.7 386.6 367.5 281.8 358.6 210.9 324.3 228.6 398.2 539.2 382.2 402.1 196.0 313.5 209.4 191.4 425.2 252.6 402.0 223.4 305.6 441.7 352.8 747.3 578.2 310.0 222.9 359.9 283.7 439.4 222.6 262.6 325.7 250.7 341.2 937.6 308.2 230.0 228.3 408.9 187.5 183.4 216.5 212.4 701.7 467.4 337.8 409.7 177.4 241.4 204.4 279.8 305.7 419.8 226.7 333.1 369.0 296.3 390.4 178.1 168.2 179.0 138.9 106.7 193.1 130.8 154.2 144.3 119.4 220.4 127.9 144.2 134.5 61.5 135.5 238.4 107.3 178.6 221.6 95.5 97.4 116.2 115.0 99.0 109.0 105.7 107.1 110.1 105.0 107.1 110.4 130.3 96.1 54.9 30.3 135.5 381.4 417.8 575.6 280.6 149.6 149.5 159.1 325.1 128.7 246.3 112.2 43.8 315.0 128.0 583.7 669.1 413.3 257.6 172.2 110.9 146.5 149.7 148.5 22.1 345.7 437.6 142.6 158.0 199.9 112.3 197.5 165.9 79.2 266.1 129.5 30.7 305.1 284.8 164.8 220.3 110.8 169.9 180.2 224.1 16.9 264.3 275.5 92.7 23.1 26.0 443.5 497.2 166.3 172.2 386.3 610.9 324.3 119.5 161.1 177.5 170.3 289.0 359.7 149.7 493.3 420.4 396.5 129.6 210.5 355.7 568.1 VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 349.4;Muller glia cells: 265.8" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 398.9;U-87 MG: 628.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" 155.8 52.7 17.6 36.5 20.3 45.5 92.4 34.2 28.2 45.2 46.8 32.6 50.9 104.0 10.5 61.3 40.9 80.1 208.3 22.8 25.1 116.9 217.3 94.1 9.3 27.0 38.5 25.0 68.1 105.0 22.3 46.2 26.8 120.3 21.4 229.1 32.1 17.8 221.2 44.2 44.6 57.1 19.6 70.1 63.9 5.3 32.0 5.6 270.9 150.9 9.5 122.3 61.7 24.9 76.5 13.4 12.5 71.8 21.0 32.9 84.2 45.6 81.1 29.7 58.4 43.1 9.9 24.9 35.5 27.7 305.4 30.6 34.0 92.0 52.0 27.4 10.4 19.0 17.8 29.2 220.3 20.8 40.4 58.0 178.6 290.6 286.2 398.9 7.7 21.0 35.7 121.7 109.4 31.3 2.3 28.3 7.9 221.2 19.2 2.3 12.0 60.5 114.8 62.9 22.3 46.8 65.6 44.4 162.0 16.1 17.3 75.1 10.4 122.6 32.9 179.2 76.1 68.8 43.6 49.1 628.6 47.9 43.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 20.3 34.2 28.2 22.8 25.1 27.0 38.5 26.8 19.6 32.0 24.9 63.6 349.4 84.7 121.5 9.8 70.5 51.2 76.8 60.3 37.8 67.0 57.1 164.7 77.2 85.7 22.0 31.3 1.3 11.6 92.9 1.9 54.7 0.0 38.4 59.1 29.0 27.4 21.3 12.1 40.8 6.3 69.7 124.4 121.2 112.0 111.7 17.5 116.0 13.9 180.0 17.0 71.8 12.2 16.2 199.0 0.3 1.8 144.1 28.4 10.3 11.3 265.8 0.0 124.1 1.8 86.0 47.1 3.4 15.9 119.4 61.9 20.5 11.4 43.9 0.0 42.1 79.1 1.1 1.9 82.0 78.3 7.9 11.4 17.4 51.0 137.5 VPS26C "DCRA, DSCR3" ENSG00000157538 "VPS26 endosomal protein sorting factor C" O14972 21 37223420-37267919 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 26.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 26.4;Hofbauer cells: 32.7;Pancreatic endocrine cells: 33.2;Proximal tubular cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023288 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA023288: AB_1847872" "unprognostic (1.01e-3)" "unprognostic (6.42e-2)" "unprognostic (7.96e-3)" "unprognostic (2.15e-2)" "unprognostic (4.10e-3)" "unprognostic (2.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "unprognostic (7.76e-2)" "unprognostic (5.40e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.54e-4)" "unprognostic (1.72e-1)" "unprognostic (3.24e-1)" "unprognostic (5.24e-2)" "unprognostic (3.16e-1)" 19.8 24.5 14.8 18.5 16.1 21.4 15.8 16.8 15.8 16.3 15.9 26.6 28.0 14.8 11.4 21.2 13.8 19.6 24.9 14.4 15.6 32.9 29.5 22.1 22.6 16.1 15.9 17.4 22.6 17.7 8.6 21.4 16.6 14.3 26.0 13.6 16.9 15.8 31.5 15.7 26.9 19.9 16.2 20.2 21.2 7.5 16.5 28.1 18.1 37.8 23.6 21.9 14.2 17.6 31.8 13.8 30.2 26.5 55.4 49.4 34.3 29.9 66.2 26.6 40.2 19.2 32.7 22.0 11.7 70.0 63.9 15.0 32.6 32.1 26.1 52.8 23.5 37.6 13.6 18.7 49.1 27.8 24.3 43.5 31.2 31.0 50.4 48.1 51.4 40.5 24.0 46.8 52.5 14.1 47.2 23.7 34.4 48.7 13.8 44.8 14.5 32.5 32.8 23.7 24.4 32.6 20.6 40.9 65.5 39.0 38.4 22.0 41.0 30.6 10.8 33.2 18.5 71.3 78.0 30.3 48.3 47.9 35.2 58.6 48.6 84.9 50.7 60.5 46.8 37.5 43.1 45.4 47.7 29.4 39.8 41.0 50.1 52.9 55.7 19.4 54.9 54.1 14.8 16.1 16.8 15.8 14.4 15.6 16.1 15.9 16.6 16.2 16.5 17.6 18.1 9.6 21.9 0.0 4.3 0.0 0.0 0.0 0.0 0.0 14.5 13.3 0.0 0.0 6.8 9.2 0.0 16.0 23.8 0.0 21.5 26.4 0.0 12.5 12.7 8.4 0.0 0.0 0.0 28.0 26.4 5.4 0.0 16.1 8.8 19.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 16.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.1 0.0 0.0 29.7 4.4 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 14.6 8.5 10.1 0.0 0.0 VPS29 "DC15, DC7, PEP11" ENSG00000111237 "VPS29 retromer complex component" Q9UBQ0 12 110491083-110502111 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039748 Uncertain Supported Vesicles,Cytosol NA NA 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA039748: AB_10674426" "unprognostic (9.46e-2)" "unprognostic (3.46e-3)" "unprognostic (2.16e-2)" "unprognostic (2.58e-1)" "unprognostic (3.08e-1)" "unprognostic (2.26e-2)" "prognostic unfavorable (2.79e-5)" "unprognostic (1.52e-1)" "unprognostic (3.37e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.64e-1)" "unprognostic (2.10e-3)" "unprognostic (2.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.11e-1)" "unprognostic (5.57e-2)" "unprognostic (4.29e-3)" 61.1 62.7 45.6 57.0 47.0 96.2 59.2 46.2 61.8 50.3 47.0 76.4 64.1 52.9 89.5 71.1 50.3 51.1 73.8 48.7 48.3 79.2 77.6 54.9 69.7 47.2 46.3 47.1 56.6 54.8 53.7 47.3 47.4 62.7 79.0 99.6 58.5 71.3 127.3 46.8 65.7 67.1 48.0 76.5 62.8 32.6 46.1 63.2 54.1 100.8 72.0 65.1 50.6 51.1 103.5 98.6 91.9 65.6 100.4 98.7 72.6 94.9 98.1 93.9 84.2 100.0 87.0 94.0 97.1 94.3 87.7 95.5 123.1 88.0 97.0 112.2 98.9 115.4 122.6 83.0 87.4 139.5 97.1 66.0 73.3 79.3 87.4 114.1 166.0 116.6 112.1 85.5 170.0 51.9 110.3 196.4 52.6 90.9 124.8 72.2 93.5 131.8 157.0 149.7 98.1 51.8 107.9 94.0 122.8 78.5 128.6 106.0 94.0 80.6 53.4 112.9 113.0 58.0 87.5 112.1 93.9 130.8 87.8 246.2 262.7 259.4 139.1 356.8 155.3 195.9 175.5 164.9 318.3 158.7 159.8 156.8 178.7 202.9 405.4 214.0 224.8 385.1 45.6 47.0 46.2 61.8 48.7 48.3 47.2 46.3 47.4 48.0 46.1 51.1 138.8 76.9 96.2 21.2 93.7 143.5 172.6 395.9 70.6 39.0 93.4 109.2 282.4 90.1 209.7 101.2 27.1 192.8 116.5 156.3 289.5 231.0 56.8 94.7 79.8 125.0 83.2 147.5 30.2 179.8 187.6 120.2 60.1 104.1 153.9 78.1 94.9 158.7 409.9 42.1 26.7 149.8 248.2 158.0 296.1 82.6 92.2 178.7 177.9 30.9 295.2 107.9 101.0 22.6 30.4 217.9 182.2 105.7 94.8 157.4 142.2 404.7 131.1 111.8 157.8 81.9 212.1 256.4 148.4 108.3 173.0 178.8 111.2 105.8 164.5 187.7 VPS39 "KIAA0770, VAM6" ENSG00000166887 "VPS39 subunit of HOPS complex" Q96JC1 15 42158701-42208307 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.39e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-2)" "prognostic favorable (3.21e-7)" "unprognostic (9.85e-2)" "unprognostic (2.14e-2)" "unprognostic (3.40e-3)" "unprognostic (2.59e-2)" "unprognostic (2.71e-1)" "unprognostic (2.81e-2)" "unprognostic (1.01e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.53e-1)" "unprognostic (4.51e-1)" "unprognostic (3.28e-2)" "unprognostic (5.04e-2)" 24.2 24.9 16.0 18.5 17.0 23.8 19.0 13.7 19.8 23.5 12.4 22.1 18.5 23.8 24.7 20.4 25.3 20.6 28.3 17.8 17.5 22.3 13.0 24.5 23.0 15.8 16.7 21.1 26.5 43.7 19.8 22.0 16.6 24.1 19.8 21.3 22.0 26.1 36.5 29.4 21.4 27.3 15.9 22.9 20.9 20.9 19.0 31.6 26.6 34.7 26.2 20.4 17.5 15.6 15.6 21.6 30.7 35.0 55.2 52.9 19.5 27.3 49.1 32.5 34.1 18.5 13.2 13.9 27.0 50.1 34.0 36.0 24.1 27.4 29.8 43.6 13.7 33.7 34.6 17.4 38.1 30.8 25.0 46.6 38.8 30.5 31.4 38.0 34.3 38.2 25.2 37.4 36.4 13.9 23.7 17.2 19.1 34.9 18.4 17.9 28.6 22.0 23.7 36.0 27.2 39.7 22.5 21.5 14.4 31.5 34.5 39.7 37.6 28.0 11.8 33.9 20.3 31.7 45.3 20.2 34.2 27.6 23.2 38.5 14.7 18.2 14.9 16.4 15.1 15.2 13.3 16.1 15.6 11.9 13.4 12.7 16.6 20.8 15.6 6.7 13.1 18.5 16.0 17.0 13.7 19.8 17.8 17.5 15.8 16.7 16.6 15.9 19.0 15.6 14.4 22.4 43.2 27.1 15.7 3.6 3.3 5.6 10.8 11.7 14.0 13.2 57.0 15.7 11.4 9.2 14.6 10.3 12.6 17.5 1.9 7.3 11.4 16.0 16.8 14.4 9.6 16.6 31.2 8.0 7.8 13.7 24.5 15.7 9.5 15.3 9.7 11.8 12.2 11.8 32.2 11.9 10.2 16.9 4.4 21.6 12.2 14.7 3.6 30.9 16.0 13.5 8.2 29.1 34.4 10.2 11.4 13.9 28.7 5.8 14.7 6.2 13.3 11.6 0.0 8.9 10.7 5.2 4.5 12.6 7.0 13.4 13.7 10.5 10.0 4.5 VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "HPA030968: AB_10602585, HPA030969: AB_2673679" "prognostic unfavorable (7.02e-4)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.17e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.83e-2)" "unprognostic (3.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.96e-1)" "unprognostic (3.24e-1)" 22.2 20.9 16.6 25.7 19.0 30.6 31.6 20.2 20.3 23.2 12.5 34.9 38.2 23.4 25.4 39.1 27.3 23.0 33.9 18.9 18.9 34.5 45.4 21.5 33.4 17.4 18.1 21.0 19.3 28.3 9.9 32.1 17.8 22.5 39.9 29.2 18.2 19.6 55.7 30.7 37.0 26.3 21.1 23.1 23.5 18.3 18.2 45.4 27.6 58.3 39.1 35.8 20.3 22.2 56.5 47.5 75.8 116.8 65.3 71.4 52.3 124.7 74.0 111.6 105.8 80.9 43.0 91.2 82.1 112.6 84.6 70.2 81.5 85.1 153.4 62.3 71.7 99.2 46.2 97.0 48.2 155.6 55.2 59.4 97.7 111.8 71.7 59.8 72.4 69.7 93.7 44.5 94.5 82.1 101.8 80.7 57.0 72.1 53.8 92.1 60.8 55.8 86.4 61.5 79.0 61.5 70.1 53.3 63.7 62.9 57.8 104.4 53.0 50.0 69.6 84.7 90.8 43.5 80.9 103.8 32.7 85.5 77.8 222.4 90.0 151.9 64.3 114.5 83.5 85.6 72.8 76.0 90.9 84.8 79.8 80.4 56.0 97.5 120.3 55.9 79.0 121.5 16.6 19.0 20.2 20.3 18.9 18.9 17.4 18.1 17.8 21.1 18.2 22.2 16.7 22.4 20.3 22.5 25.8 25.2 19.2 25.5 25.6 9.7 16.5 18.3 47.8 12.8 24.5 16.5 0.0 32.7 23.9 40.2 17.6 31.5 4.5 30.7 30.4 17.5 21.6 23.1 40.1 28.0 36.4 25.4 16.8 28.0 12.6 18.1 11.4 24.7 27.9 11.8 38.7 24.7 14.2 20.9 14.3 2.2 11.8 20.0 8.8 40.3 28.0 23.9 35.0 25.6 48.7 30.1 18.3 12.4 16.4 17.2 30.0 31.6 36.6 12.6 6.6 16.8 18.4 23.6 24.9 28.8 31.0 31.7 23.8 25.3 25.9 18.8 VWA8 KIAA0564 ENSG00000102763 "Von Willebrand factor A domain containing 8" A3KMH1 13 41566835-41961120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 161.9;Excitatory neurons: 183.9;Inhibitory neurons: 252.6;Oligodendrocyte precursor cells: 151.3;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039075, HPA045478" Uncertain Approved "Vesicles,Lipid droplets" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Lipid droplets" "HPA039075: AB_2676334, HPA045478: AB_2679341" "unprognostic (9.93e-2)" "unprognostic (4.12e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-3)" "unprognostic (4.14e-2)" "unprognostic (1.50e-2)" "prognostic favorable (8.56e-4)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (3.31e-3)" "unprognostic (5.35e-2)" "unprognostic (2.44e-1)" "prognostic favorable (6.38e-14)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" 8.0 7.8 5.1 3.7 6.8 5.7 8.7 9.5 5.6 9.2 14.3 6.8 7.1 7.2 5.5 5.7 6.4 5.3 13.7 2.9 5.0 17.6 21.6 4.9 4.5 5.5 6.4 6.3 7.3 14.6 3.8 5.0 6.2 6.1 7.5 15.1 7.7 5.8 29.3 4.1 5.4 6.0 4.0 3.7 6.6 4.1 7.9 7.7 7.1 35.1 4.4 6.2 3.8 5.1 5.2 7.6 7.6 10.5 7.0 10.2 7.1 8.2 12.0 7.3 5.8 10.0 8.2 13.8 5.4 7.2 5.9 18.3 7.1 20.0 9.1 15.6 12.3 13.1 7.0 12.7 7.5 17.3 1.7 12.0 12.2 7.0 16.7 9.9 7.4 10.8 12.7 9.6 6.5 7.0 9.8 8.9 11.4 13.6 7.0 0.1 4.8 14.5 19.7 18.8 4.7 10.0 10.2 15.9 11.4 8.3 6.6 13.2 6.6 5.5 5.8 7.1 7.8 9.7 9.9 21.4 6.1 8.2 7.3 0.6 0.4 0.0 1.1 0.4 1.6 0.7 0.6 1.0 0.9 1.0 0.8 1.2 0.2 1.6 0.6 0.5 0.4 0.8 5.1 6.8 9.5 5.6 2.9 5.0 5.5 6.4 6.2 4.0 7.9 5.1 7.5 16.0 2.6 161.9 9.2 4.0 16.5 8.2 9.6 10.7 13.1 5.7 45.5 11.5 10.4 5.5 35.5 7.6 7.3 7.5 1.9 3.7 35.4 10.1 7.6 5.3 3.0 12.0 183.9 1.6 2.1 6.2 15.8 14.4 0.0 5.8 2.2 16.5 3.9 3.3 252.6 7.8 4.1 3.8 4.0 14.2 5.9 11.5 5.4 69.3 4.1 4.9 4.1 151.3 146.1 4.0 9.3 5.3 18.2 16.0 9.4 8.2 6.7 42.6 0.0 7.6 8.9 5.5 4.8 12.5 2.8 2.9 10.4 8.5 9.4 11.9 WBP1L "C10orf26, FLJ20154, OPAL1" ENSG00000166272 "WW domain binding protein 1 like" Q9NX94 10 102743948-102834516 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037635, HPA038371" Uncertain Approved Nucleoplasm,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Microtubules Nucleoplasm "HPA037635: AB_10672462, HPA038371: AB_2675980" "unprognostic (3.28e-2)" "unprognostic (6.46e-2)" "unprognostic (1.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (5.35e-3)" "unprognostic (2.73e-2)" "unprognostic (3.33e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.43e-3)" "unprognostic (2.55e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.56e-6)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (4.88e-2)" "unprognostic (1.53e-1)" 34.9 43.2 21.3 22.3 23.1 5.0 25.8 20.7 20.1 26.4 28.7 27.7 15.2 27.4 18.9 21.1 29.4 25.1 24.1 19.8 22.4 20.8 42.1 24.5 21.4 32.0 23.9 26.5 15.5 41.7 22.9 23.5 23.6 26.9 15.0 5.7 22.6 22.4 54.6 37.5 19.9 26.2 25.9 21.3 25.7 14.2 24.7 33.7 41.1 49.0 18.9 24.5 20.5 22.6 21.0 26.8 14.5 24.5 47.0 37.9 29.5 21.0 56.7 20.5 25.8 18.3 31.9 18.1 27.8 32.5 16.5 22.7 10.7 18.2 15.5 18.3 11.3 36.6 11.6 13.3 30.3 17.8 41.7 41.2 32.0 26.4 20.3 47.0 40.5 21.6 18.1 22.0 35.6 27.5 21.7 19.8 11.0 16.1 12.9 42.9 38.3 11.7 18.2 20.4 3.4 13.9 11.5 11.6 24.1 26.0 47.2 19.5 30.4 19.6 20.1 22.3 19.1 40.6 22.9 13.0 27.7 33.6 8.8 7.8 12.2 16.2 8.7 14.8 7.0 6.5 7.3 8.4 8.7 6.1 6.5 6.9 15.2 12.9 19.4 5.4 8.2 10.6 21.3 23.1 20.7 20.1 19.8 22.4 32.0 23.9 23.6 25.9 24.7 22.6 13.3 22.4 19.0 29.4 12.2 8.2 8.0 17.0 11.4 6.4 25.0 15.4 15.7 12.8 17.8 12.9 0.0 33.9 17.2 26.4 1.9 14.2 2.0 9.7 11.0 20.4 9.1 11.1 24.6 25.3 14.6 29.3 16.8 12.7 38.1 16.4 27.1 56.2 27.7 13.5 26.4 14.6 14.2 46.6 13.1 1.8 13.1 28.8 10.6 40.3 28.9 9.8 29.9 19.1 26.3 24.6 13.7 19.5 9.0 29.9 18.3 8.9 20.5 3.8 19.7 16.6 17.7 4.4 5.8 11.3 11.8 40.0 14.4 8.9 12.2 11.3 WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoli "HPA036389: AB_10670716" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "unprognostic (8.17e-2)" "unprognostic (3.59e-3)" "unprognostic (1.24e-2)" "unprognostic (9.40e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (1.52e-1)" "unprognostic (6.14e-2)" "unprognostic (4.78e-2)" "unprognostic (4.58e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.66e-1)" "unprognostic (9.69e-3)" "unprognostic (4.48e-2)" 2.6 3.6 2.1 2.7 2.3 3.6 3.6 2.3 3.2 2.5 1.4 3.0 4.1 3.2 3.2 3.2 3.1 2.3 4.0 2.2 2.9 5.2 4.2 1.7 3.3 2.5 2.1 3.2 2.2 3.5 1.9 2.7 2.7 2.2 4.0 2.6 1.9 2.3 4.8 3.6 2.9 3.4 1.5 2.1 2.3 3.5 2.8 3.2 3.2 6.0 3.7 4.1 2.3 2.5 5.3 5.8 6.4 12.5 12.3 10.4 11.4 7.6 6.6 10.1 9.8 14.8 7.5 10.2 7.2 6.6 8.5 6.6 18.2 13.3 16.0 4.6 11.1 17.0 9.0 17.7 8.0 22.1 9.9 9.5 9.4 12.0 23.6 6.4 10.8 10.2 26.7 5.9 11.3 6.5 14.8 13.3 14.9 7.3 14.3 11.1 9.7 16.1 11.2 6.5 11.4 9.8 6.5 8.2 9.8 11.0 4.7 14.1 8.3 8.3 6.9 7.4 8.4 8.0 12.8 16.3 8.7 15.3 8.8 1.3 1.6 0.6 1.4 1.7 2.0 1.9 1.3 1.4 2.1 1.9 1.7 1.7 0.6 1.3 1.7 2.4 1.6 1.1 2.1 2.3 2.3 3.2 2.2 2.9 2.5 2.1 2.7 1.5 2.8 2.5 10.1 9.6 16.9 12.1 13.6 20.5 21.4 24.4 13.1 10.2 8.4 9.1 27.9 7.2 19.1 5.5 2.1 25.3 7.9 7.8 15.6 18.0 14.3 14.7 25.3 12.6 5.4 22.1 19.2 10.6 34.9 16.5 9.7 13.3 15.2 15.8 8.2 15.0 18.0 15.2 20.3 10.6 24.4 7.2 6.0 8.9 17.1 9.2 1.8 12.2 13.7 6.4 5.2 10.6 9.9 14.2 6.6 15.4 9.3 17.3 13.9 38.1 15.7 8.3 13.1 20.1 41.9 43.0 32.3 18.2 17.3 21.5 10.7 21.0 19.2 17.0 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 33.6 22.1 16.3 25.8 21.5 18.2 40.6 19.6 16.3 23.6 24.3 26.9 26.3 23.0 24.6 33.1 18.5 45.3 50.8 14.3 20.7 40.9 111.7 27.2 39.0 18.3 19.0 24.7 28.0 116.3 9.8 36.9 19.7 33.4 33.1 43.2 25.9 25.6 171.4 40.8 28.1 24.6 18.1 45.7 34.3 29.5 19.5 22.7 32.6 122.2 30.6 33.7 15.8 23.1 59.8 27.1 18.3 13.1 23.0 22.4 16.3 21.0 22.5 16.5 19.5 18.9 35.3 24.9 14.0 36.5 22.9 49.3 26.4 34.1 28.5 31.6 21.0 28.7 24.4 44.7 16.8 11.7 14.0 20.5 42.5 18.2 33.3 25.3 74.1 29.0 14.3 28.7 28.4 29.6 27.7 8.1 11.2 82.6 30.0 18.0 21.4 22.5 37.3 44.5 5.5 12.9 21.2 104.7 23.0 39.8 31.3 10.8 84.4 23.9 28.7 26.3 10.7 33.9 22.0 25.7 29.9 1.6 19.0 6.2 2.1 3.9 5.2 1.9 4.6 2.7 6.4 5.3 1.5 2.4 7.5 4.7 1.3 2.4 2.2 1.9 6.5 2.0 16.3 21.5 19.6 16.3 14.3 20.7 18.3 19.0 19.7 18.1 19.5 23.1 51.2 25.6 22.6 29.0 13.0 35.8 26.9 15.4 26.7 28.8 41.7 23.5 82.7 44.3 19.2 29.5 58.4 28.3 19.5 23.7 43.0 20.5 42.1 22.6 20.1 32.3 23.6 3.0 55.3 37.6 3.3 27.6 35.2 35.5 3.8 18.0 62.4 88.8 55.9 40.4 134.6 25.3 14.2 95.2 28.1 12.7 32.3 43.0 30.2 61.8 18.6 23.3 18.6 60.3 103.8 45.1 16.0 36.5 18.5 45.1 15.8 45.7 17.2 52.6 6.6 18.8 16.6 12.4 21.2 28.8 39.5 23.0 32.0 25.1 19.7 38.3 XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913976 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: AB_2677993" "prognostic unfavorable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 9.2 7.7 6.5 9.2 7.5 8.3 9.7 6.8 7.0 9.6 12.9 12.4 10.1 8.4 10.0 11.5 7.4 8.6 7.8 5.8 8.2 11.8 12.1 8.5 10.4 7.6 8.1 7.5 8.3 18.4 6.3 8.6 7.3 8.5 10.1 21.4 8.6 7.4 10.3 8.8 10.1 7.4 8.5 10.4 10.2 4.2 8.1 8.9 14.9 11.9 8.6 9.6 6.1 10.3 15.8 13.2 10.2 8.8 11.8 15.0 13.3 16.9 12.4 8.9 7.7 5.9 17.9 14.7 24.3 14.4 17.1 5.6 15.3 10.5 16.3 15.5 8.3 9.9 11.1 9.2 14.9 18.1 19.7 10.4 16.0 14.9 19.0 10.2 12.7 10.8 15.9 16.4 17.6 16.5 10.2 8.8 8.4 15.6 10.3 10.8 11.9 15.6 13.4 22.6 6.8 10.0 22.9 13.0 13.5 9.0 8.0 8.7 15.7 0.5 6.0 27.0 18.9 13.8 14.9 15.8 18.3 12.7 11.5 9.3 1.8 2.6 3.3 1.5 3.0 3.1 2.4 3.6 1.0 4.0 2.7 1.9 5.6 2.4 2.9 2.9 1.8 1.5 6.5 7.5 6.8 7.0 5.8 8.2 7.6 8.1 7.3 8.5 8.1 10.3 50.0 80.1 91.6 26.4 42.1 26.6 36.3 35.0 28.5 72.1 29.7 19.9 44.5 44.3 55.2 53.3 95.9 17.9 41.7 122.9 27.4 36.0 2.7 38.4 44.9 55.0 47.4 23.5 30.0 54.0 30.0 38.4 39.8 50.4 60.7 30.9 64.2 85.8 29.0 75.7 34.9 62.2 26.4 43.6 33.0 4.1 42.6 44.2 8.8 29.0 45.8 45.8 55.6 32.6 41.9 65.4 53.5 51.6 39.5 53.0 59.2 59.8 50.6 133.7 65.7 43.6 34.9 15.2 21.0 30.8 35.5 38.0 40.8 30.0 48.0 68.1 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: AB_1858932, HPA053646: AB_2682216" "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.23e-1)" 17.7 12.9 15.6 11.8 17.8 20.7 22.2 19.2 22.0 18.8 14.0 26.3 19.0 15.5 24.8 20.0 17.9 15.8 34.3 17.0 12.9 24.2 32.5 16.3 19.3 16.8 13.9 23.9 26.6 24.7 21.5 36.6 18.3 17.1 28.7 30.6 23.8 18.2 44.9 22.0 26.0 15.2 16.5 16.1 21.3 7.0 15.5 23.3 27.8 40.7 20.6 16.6 16.9 16.8 21.7 14.1 14.8 30.4 22.6 29.0 16.3 38.5 44.6 14.8 18.5 8.7 30.0 15.2 6.0 38.3 17.4 28.7 18.5 32.6 10.4 94.6 27.1 34.1 32.7 17.0 16.0 58.0 33.2 32.2 31.9 11.9 27.2 27.5 30.9 35.2 18.6 54.0 28.6 25.5 14.6 28.6 3.8 20.9 31.9 31.0 23.7 50.2 28.9 36.2 27.2 22.4 21.4 21.7 24.5 10.4 21.8 28.4 27.7 28.9 22.0 9.2 12.4 8.8 41.2 10.5 19.1 49.5 23.8 1.7 3.4 8.9 3.2 2.9 2.3 2.1 2.6 2.9 2.3 1.5 1.4 2.2 1.7 1.7 3.8 1.7 3.2 1.8 15.6 17.8 19.2 22.0 17.0 12.9 16.8 13.9 18.3 16.5 15.5 16.8 41.5 35.3 17.9 12.4 7.5 9.7 18.7 13.9 9.6 59.0 15.3 10.8 56.3 20.0 12.5 27.6 6.2 8.4 15.9 24.8 19.6 12.3 0.5 8.5 39.0 24.1 23.4 9.9 16.6 21.1 8.1 26.4 12.8 11.1 7.0 42.6 23.6 25.0 16.4 25.2 14.1 25.1 14.2 20.2 19.1 2.1 36.7 18.3 12.4 12.2 23.9 21.3 13.4 20.6 14.9 15.5 21.9 63.2 6.2 18.5 35.2 19.0 8.1 40.9 19.7 25.5 12.3 0.4 4.9 23.7 11.1 6.7 11.0 73.0 27.2 20.9 ZBTB38 "CIBZ, FLJ35036, PPP1R171, ZNF921" ENSG00000177311 "Zinc finger and BTB domain containing 38" Q8NAP3 3 141324213-141449792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 261.2;RPMI-8226: 395.1;U-266/70: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014865, HPA059378" Enhanced Nucleoplasm No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA014865: AB_2732412, HPA059378: AB_2683998" "unprognostic (1.78e-1)" "unprognostic (3.18e-1)" "unprognostic (2.97e-3)" "unprognostic (1.93e-1)" "unprognostic (2.78e-1)" "unprognostic (2.84e-2)" "unprognostic (4.01e-2)" "unprognostic (7.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.38e-1)" "unprognostic (2.01e-3)" "unprognostic (4.53e-1)" "unprognostic (5.07e-3)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.29e-2)" "unprognostic (1.04e-1)" 27.1 42.3 7.7 30.4 14.4 11.3 25.4 34.1 18.1 47.8 11.9 39.1 28.8 65.5 20.3 26.8 32.3 47.3 42.1 9.8 9.6 34.1 24.2 31.7 34.4 11.8 12.8 38.2 33.6 53.5 8.3 34.8 13.9 28.1 40.8 39.0 33.0 33.9 55.1 16.7 31.5 56.0 8.0 23.9 29.2 30.1 14.0 14.3 38.0 31.0 38.7 35.0 11.6 28.3 56.4 82.0 9.3 18.7 84.8 79.4 12.5 89.0 106.7 84.6 122.8 43.0 32.4 1.9 36.1 78.1 65.7 15.5 10.8 75.4 191.5 54.5 15.2 15.8 74.4 25.2 94.0 1.0 22.4 60.1 43.8 89.9 180.6 137.8 65.6 1.5 16.9 261.2 96.9 6.0 1.0 3.5 9.7 15.7 10.1 1.1 27.5 395.1 54.3 34.3 3.6 13.7 130.7 12.4 46.0 16.4 26.8 13.8 159.5 68.5 17.5 134.9 42.2 259.7 163.4 19.8 116.7 1.8 38.5 27.9 5.5 15.2 25.9 8.2 19.3 16.6 16.7 26.4 8.1 7.2 12.9 21.0 6.3 24.1 7.2 3.9 24.4 11.5 7.7 14.4 34.1 18.1 9.8 9.6 11.8 12.8 13.9 8.0 14.0 28.3 70.7 76.9 64.6 38.2 48.0 20.4 33.8 36.3 24.5 89.8 44.0 41.1 114.8 64.3 61.2 58.8 75.0 32.6 66.5 57.8 29.4 39.3 284.2 63.4 107.9 81.2 36.0 17.7 115.4 31.8 17.0 59.3 35.2 125.9 68.9 40.0 59.3 34.9 32.6 141.3 107.9 37.0 24.4 23.4 43.1 118.6 70.5 37.9 39.2 65.6 70.8 59.3 55.6 56.8 105.3 69.6 37.0 103.0 221.9 36.8 38.9 51.1 46.6 73.3 118.3 71.9 106.9 9.4 11.4 19.0 18.6 124.9 88.4 35.6 82.5 43.5 ZBTB8OS ARCH ENSG00000176261 "Zinc finger and BTB domain containing 8 opposite strand" Q8IWT0 1 32600172-32650903 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046315 Approved Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA046315: AB_2679623" "unprognostic (3.41e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "unprognostic (9.08e-2)" "unprognostic (1.82e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (9.63e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (5.18e-2)" "unprognostic (3.84e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.11e-8)" "unprognostic (1.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-1)" "unprognostic (1.42e-1)" 21.5 25.5 21.1 28.7 21.0 21.5 20.6 23.7 34.4 17.1 20.4 33.8 32.2 16.3 35.6 27.2 18.3 14.7 32.4 20.9 22.5 28.2 34.5 20.3 36.9 20.9 20.8 12.4 27.4 21.5 27.7 14.9 21.1 21.6 33.3 27.6 22.8 15.9 43.6 17.0 29.1 20.2 20.3 27.1 28.5 16.5 21.9 16.9 18.3 35.5 43.8 21.4 18.2 22.2 56.1 31.8 27.9 47.2 47.7 43.3 38.1 62.1 62.3 48.5 49.0 75.5 60.9 62.0 55.9 45.6 53.5 41.1 48.7 48.5 64.4 83.2 44.8 50.5 67.4 127.0 39.2 73.2 44.9 43.4 52.3 42.7 51.2 30.3 53.6 74.6 50.8 81.6 62.9 44.3 56.2 42.4 86.1 86.5 48.7 44.9 59.8 60.7 58.7 65.7 55.9 43.0 50.1 49.9 83.3 74.8 34.2 59.8 38.4 67.2 40.8 55.0 78.9 123.1 130.8 177.0 48.1 89.6 68.1 37.5 57.7 71.5 46.3 71.0 44.8 73.0 50.5 56.0 41.6 54.0 41.9 45.1 66.3 48.0 78.0 53.6 86.1 37.8 21.1 21.0 23.7 34.4 20.9 22.5 20.9 20.8 21.1 20.3 21.9 22.2 39.4 22.4 53.7 32.0 56.3 17.2 31.2 69.5 18.2 46.9 28.5 34.7 69.3 30.0 53.3 38.6 43.8 49.3 54.5 68.8 90.1 60.5 38.1 42.5 38.1 34.4 37.7 46.1 58.3 52.7 61.8 35.9 35.2 45.3 44.2 24.0 33.2 82.5 72.3 16.8 60.5 53.2 71.2 61.9 19.8 30.5 36.7 47.4 51.6 21.5 82.2 35.7 75.2 35.7 46.8 68.4 71.6 46.3 79.9 32.8 115.9 139.4 42.0 56.5 32.9 27.3 51.7 52.9 30.0 28.1 15.6 65.1 50.3 31.2 49.7 37.8 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZFP1 "FLJ34243, ZNF475" ENSG00000184517 "ZFP1 zinc finger protein" Q6P2D0 16 75148494-75172236 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-698: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044916, HPA062910" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA044916: AB_2679144, HPA062910: AB_2684902" "unprognostic (1.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.24e-5)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.99e-1)" "unprognostic (1.50e-1)" "unprognostic (4.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.13e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (9.80e-4)" "unprognostic (5.55e-1)" "unprognostic (6.64e-2)" "unprognostic (2.08e-1)" 4.2 3.3 3.7 1.7 4.4 1.8 3.9 4.4 5.1 4.8 1.7 5.4 1.7 5.7 2.2 2.7 4.8 2.7 3.6 4.6 3.4 3.7 11.1 3.5 3.1 3.3 3.0 5.1 2.1 4.6 3.8 3.0 3.3 2.9 2.0 5.8 2.2 3.1 5.8 2.7 3.0 4.0 3.7 2.5 3.0 4.2 3.7 8.2 4.8 4.3 3.2 4.7 3.6 5.3 3.1 6.6 9.1 8.2 5.1 6.7 3.6 3.7 4.4 8.2 9.8 5.3 2.4 13.1 4.2 3.0 3.2 3.8 8.1 5.6 9.5 7.2 4.9 4.8 2.4 4.0 4.4 4.7 14.8 4.5 5.5 6.1 7.9 8.6 5.4 12.3 5.6 2.7 6.4 11.9 16.4 4.6 2.8 2.6 2.5 15.1 4.0 4.2 3.6 2.8 9.0 7.2 9.0 2.7 3.5 2.3 6.0 3.9 3.7 7.4 7.9 3.4 4.3 11.2 11.5 28.6 3.6 6.7 5.8 1.1 0.7 0.2 1.5 1.2 1.6 1.2 1.1 1.7 0.7 1.6 1.4 1.5 0.0 1.9 0.5 0.3 1.7 0.9 3.7 4.4 4.4 5.1 4.6 3.4 3.3 3.0 3.3 3.7 3.7 5.3 5.4 6.4 4.8 6.8 5.1 5.4 2.5 2.3 5.7 6.9 3.8 3.4 4.2 1.5 2.0 1.8 0.0 2.9 7.6 1.0 1.9 3.6 4.6 2.9 7.5 5.3 7.2 4.6 9.5 2.3 2.7 5.9 0.0 3.9 1.3 5.1 3.9 11.7 2.0 13.5 8.5 0.9 0.0 4.1 2.7 5.2 3.4 1.8 1.8 7.5 3.6 6.8 4.1 7.1 11.7 1.6 1.0 4.1 2.7 2.3 0.8 3.6 2.6 3.8 0.0 5.6 8.2 15.9 8.8 5.0 5.8 4.1 5.5 4.7 1.8 2.4 ZFP3 "FLJ30726, ZNF752" ENSG00000180787 "ZFP3 zinc finger protein" Q96NJ6 17 5078467-5096374 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 11.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;SH-SY5Y: 6.0;SiHa: 5.5" "Low region specificity" "Detected in all" "HPA053085, HPA057290" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA053085: AB_2682039, HPA057290: AB_2683400" "unprognostic (3.71e-2)" "prognostic favorable (5.68e-4)" "unprognostic (1.45e-1)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (4.32e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.38e-4)" "unprognostic (5.42e-2)" "unprognostic (3.33e-1)" "prognostic favorable (1.07e-4)" "unprognostic (4.89e-2)" "prognostic favorable (7.69e-7)" "unprognostic (8.30e-2)" "unprognostic (1.16e-1)" "unprognostic (6.32e-2)" "unprognostic (3.29e-3)" 2.6 2.6 2.9 3.9 3.7 0.9 4.7 6.4 4.4 3.3 6.7 4.8 7.1 3.4 3.3 2.7 5.8 2.5 6.8 3.2 3.4 5.2 1.2 3.8 5.3 3.9 3.9 4.9 4.6 9.4 2.1 2.7 3.4 3.9 5.7 8.0 6.0 3.7 6.8 3.5 6.1 3.2 3.2 5.1 4.4 3.1 3.9 5.0 5.8 9.7 6.2 2.8 2.3 3.7 0.0 1.0 0.2 0.0 0.9 0.4 0.0 2.2 0.0 1.7 1.9 4.5 2.0 0.0 3.1 2.2 0.8 4.5 0.0 0.0 0.9 0.0 0.1 0.1 1.9 0.0 3.0 0.0 5.8 1.5 0.0 1.2 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.2 3.2 0.4 0.0 0.6 1.5 2.7 2.7 2.7 6.0 5.5 4.5 2.9 1.0 2.7 4.4 0.0 0.0 0.8 1.5 3.2 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.8 0.6 1.0 0.9 0.6 0.8 0.6 0.9 0.5 2.1 1.5 1.1 0.0 0.7 0.8 0.3 0.6 0.7 2.9 3.7 6.4 4.4 3.2 3.4 3.9 3.9 3.4 3.2 3.9 3.7 1.8 0.0 4.2 1.6 2.1 0.3 0.4 0.9 1.2 4.1 1.6 1.4 7.8 1.5 2.1 1.8 8.4 1.2 2.4 3.1 0.0 1.7 1.8 3.1 2.7 1.8 0.0 0.8 3.0 1.1 0.4 1.8 4.6 0.8 1.3 2.9 4.2 0.1 1.7 3.3 4.5 2.2 0.0 2.5 0.2 0.5 1.5 1.2 0.0 0.0 0.9 2.8 2.1 4.5 3.1 0.6 1.0 1.2 1.8 0.6 2.6 1.4 11.0 6.0 0.0 3.0 1.5 7.1 3.8 2.3 0.1 0.8 1.6 2.9 2.5 0.5 ZNF274 "ZKSCAN19, ZSCAN51" ENSG00000171606 "Zinc finger protein 274" Q96GC6 19 58183029-58213562 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 77.1" "Low region specificity" "Detected in all" HPA028880 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Centrosome "HPA028880: AB_10601929" "unprognostic (2.38e-3)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "unprognostic (3.84e-1)" "prognostic favorable (6.16e-4)" "unprognostic (2.73e-2)" "unprognostic (1.56e-2)" "unprognostic (1.34e-1)" "unprognostic (6.57e-2)" "unprognostic (2.19e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.91e-2)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" "unprognostic (8.85e-2)" "unprognostic (2.58e-3)" 12.0 11.5 10.1 9.9 11.1 13.1 13.0 13.5 10.3 11.3 15.2 14.4 8.6 10.2 13.6 14.9 14.5 8.8 18.0 9.6 9.5 16.4 19.2 13.1 14.0 10.8 10.5 21.7 8.7 21.7 14.4 9.4 11.0 12.9 7.5 17.3 10.3 10.7 17.7 15.1 14.8 8.9 10.0 17.3 11.4 14.4 10.7 11.5 18.9 14.6 14.3 12.7 11.8 14.5 18.5 12.3 20.9 8.5 12.9 19.1 20.3 14.3 7.9 15.9 14.1 7.5 13.1 6.2 9.4 9.3 16.9 5.1 10.1 20.3 21.8 12.7 77.1 29.5 12.8 12.1 20.8 20.9 46.1 15.0 25.7 19.6 37.2 16.6 12.8 9.7 22.5 26.8 12.0 12.0 11.5 19.1 20.0 10.6 12.2 26.0 5.3 26.8 11.9 7.4 13.6 6.1 19.6 8.6 16.9 15.7 20.4 39.4 12.5 8.5 12.8 10.0 16.9 12.5 14.1 20.9 3.8 23.3 18.4 23.0 7.3 36.9 13.5 8.0 21.1 20.5 17.7 19.7 10.3 26.3 26.1 18.5 26.1 22.1 13.4 5.0 24.4 13.2 10.1 11.1 13.5 10.3 9.6 9.5 10.8 10.5 11.0 10.0 10.7 14.5 15.2 16.0 19.6 17.6 33.5 10.5 40.1 12.8 8.0 32.6 10.2 8.3 14.5 15.7 14.1 18.4 43.8 11.3 12.7 10.4 1.9 13.5 18.5 8.3 8.1 13.9 6.6 10.8 4.4 5.6 11.7 9.2 13.7 11.9 29.2 11.2 13.2 9.9 7.1 20.2 3.7 9.0 4.1 13.0 15.9 10.7 12.2 11.9 7.2 10.3 10.4 22.3 18.6 16.6 21.0 12.3 17.9 12.0 7.8 26.7 18.0 10.3 12.4 67.0 19.7 14.1 16.6 21.6 14.6 8.8 12.1 16.7 23.7 5.5 8.3 25.5 ZNF33A "FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK" ENSG00000189180 "Zinc finger protein 33A" Q06730 10 38010650-38065088 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: AB_2683199" "unprognostic (1.85e-2)" "unprognostic (1.19e-1)" "unprognostic (7.68e-3)" "unprognostic (1.48e-1)" "unprognostic (3.42e-2)" "unprognostic (1.69e-3)" "unprognostic (7.96e-3)" "unprognostic (4.89e-3)" "unprognostic (6.73e-2)" "unprognostic (9.06e-2)" "unprognostic (2.29e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (6.83e-2)" "unprognostic (7.39e-3)" 9.2 12.6 5.8 12.2 7.0 12.2 17.9 17.1 7.6 14.5 9.6 12.2 13.4 15.1 10.9 9.3 14.9 11.8 9.0 5.0 7.8 15.3 16.3 10.1 14.8 9.5 7.1 14.8 16.9 17.1 14.0 11.4 9.9 15.1 15.8 20.6 14.9 14.3 13.9 13.9 13.7 10.3 6.7 14.2 16.7 4.3 6.8 14.0 15.7 15.8 16.2 11.0 10.3 8.4 16.3 9.1 16.2 14.1 7.8 9.8 12.8 7.3 7.1 9.1 10.2 9.7 14.5 31.5 7.7 9.8 5.2 10.6 19.3 12.6 8.5 18.9 22.0 25.2 18.6 13.2 7.9 36.0 20.2 8.6 22.5 6.9 10.1 17.0 7.5 17.7 13.5 16.5 9.3 10.6 15.0 8.2 16.4 8.2 10.5 12.9 11.2 14.8 12.8 15.0 12.6 19.8 11.3 12.3 6.4 11.2 14.8 9.5 7.3 8.0 11.7 9.0 5.8 13.0 17.1 18.5 7.4 19.7 3.7 12.7 3.6 6.1 5.4 5.0 4.7 6.4 4.7 3.6 3.4 6.2 5.8 4.6 15.9 4.7 6.6 6.3 3.6 3.1 5.8 7.0 17.1 7.6 5.0 7.8 9.5 7.1 9.9 6.7 6.8 8.4 28.4 60.9 73.0 39.8 47.5 11.9 33.0 25.6 19.4 38.2 33.4 28.6 70.6 31.5 49.0 27.6 33.3 28.4 43.1 27.1 25.4 34.9 4.6 62.8 19.3 31.6 34.1 30.3 47.4 29.2 20.0 23.5 25.5 37.7 33.6 47.6 21.4 39.6 19.4 30.3 63.9 28.2 18.3 22.8 16.8 6.7 23.9 26.1 10.6 58.1 46.9 21.1 38.1 56.3 81.5 32.0 29.6 24.0 32.1 38.9 22.0 39.3 80.8 31.8 26.3 32.7 22.7 15.3 18.9 18.7 12.8 35.6 34.6 33.2 27.5 38.4 ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58418327 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 49.8" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA043408: AB_2678466, HPA048075: AB_2680251" "unprognostic (6.06e-2)" "unprognostic (3.27e-3)" "unprognostic (3.76e-3)" "unprognostic (8.15e-3)" "unprognostic (5.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (6.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (1.90e-3)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-2)" 5.7 6.7 4.6 2.9 4.5 1.8 5.0 5.4 5.5 5.6 6.0 6.6 3.5 6.9 3.8 5.8 6.8 2.3 8.9 5.1 4.3 5.3 6.6 4.3 2.5 5.3 4.6 6.1 4.9 8.4 6.7 2.7 4.6 5.0 2.6 5.1 4.7 5.7 9.8 9.0 3.5 5.1 4.0 3.3 5.6 4.7 4.5 3.2 4.7 10.9 3.4 6.1 5.0 4.1 11.7 16.7 11.2 14.7 10.8 10.7 4.5 8.9 15.8 5.4 6.7 2.7 3.5 5.8 7.0 14.7 14.2 6.5 12.1 14.6 6.1 7.5 49.8 15.7 9.6 3.5 18.3 17.3 4.3 11.1 10.4 16.5 22.8 11.9 10.9 9.5 15.8 5.4 8.9 8.3 14.4 5.4 2.8 7.6 23.2 10.4 8.4 9.0 7.6 13.7 9.0 9.5 19.5 5.6 7.4 2.9 3.7 8.6 7.0 21.2 6.5 8.9 14.3 5.0 9.5 1.3 15.2 6.0 7.1 0.0 2.2 0.8 3.2 2.1 5.2 2.1 4.3 4.5 3.4 3.3 2.3 3.6 0.7 3.2 3.5 2.9 5.1 2.7 4.6 4.5 5.4 5.5 5.1 4.3 5.3 4.6 4.6 4.0 4.5 4.1 4.2 3.2 3.9 1.0 2.3 11.2 3.2 5.6 6.2 4.1 4.8 4.3 12.8 5.7 2.1 9.2 4.2 1.0 5.9 1.6 13.7 5.6 9.6 8.1 6.1 4.6 6.7 9.5 2.0 5.1 1.5 5.6 3.6 1.8 2.5 5.5 6.8 4.7 2.6 3.3 2.2 2.3 4.1 2.4 3.3 7.8 5.3 2.1 1.8 0.0 1.3 6.1 2.1 0.5 1.6 4.9 2.8 6.4 2.6 4.2 2.1 5.5 10.2 9.2 6.6 4.4 6.3 8.1 3.7 4.3 15.9 0.4 4.0 12.3 3.2 2.0 ZNF629 "KIAA0326, ZNF65" ENSG00000102870 "Zinc finger protein 629" Q9UEG4 16 30778456-30787205 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019550, HPA056051" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus" "HPA019550: AB_1859386, HPA056051: AB_2683020" "unprognostic (1.03e-2)" "unprognostic (2.15e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (3.17e-1)" "unprognostic (6.38e-2)" "unprognostic (6.14e-2)" "unprognostic (2.98e-2)" "unprognostic (3.15e-1)" "unprognostic (6.24e-2)" "unprognostic (4.87e-3)" "unprognostic (2.66e-2)" "prognostic favorable (4.57e-10)" "unprognostic (8.41e-2)" "unprognostic (1.96e-1)" "unprognostic (5.71e-2)" "unprognostic (9.70e-2)" 5.6 9.0 5.6 3.0 6.0 4.1 5.7 7.1 5.9 6.5 4.3 6.8 5.5 8.0 4.3 5.1 6.6 3.6 12.6 5.9 6.1 7.8 4.3 5.3 1.9 6.2 6.7 6.8 5.9 15.0 6.6 3.6 5.6 6.3 4.5 7.8 6.5 6.0 9.7 8.6 5.3 6.8 5.0 4.0 7.3 4.1 7.0 3.9 5.9 9.6 2.3 6.5 5.1 5.5 9.8 15.8 23.9 18.5 11.5 10.6 3.6 10.8 15.6 16.6 14.0 9.7 8.8 1.8 10.2 17.6 5.2 11.4 11.7 14.3 11.0 0.4 17.6 13.6 14.0 10.2 12.3 4.8 8.0 17.7 10.5 10.3 8.6 13.0 8.9 0.8 20.2 0.4 14.6 20.8 7.2 6.3 12.6 4.7 6.4 24.3 18.4 0.8 13.9 15.9 22.6 25.3 10.5 19.4 2.6 7.8 14.6 17.4 10.8 15.5 10.1 10.6 8.3 0.3 0.1 0.5 10.2 11.9 5.3 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.3 0.1 0.6 0.0 0.1 5.6 6.0 7.1 5.9 5.9 6.1 6.2 6.7 5.6 5.0 7.0 5.5 4.9 19.2 9.4 5.9 2.6 1.9 3.4 4.3 5.7 16.7 4.2 3.4 28.3 4.3 6.5 9.2 4.2 1.3 1.6 5.4 1.9 8.7 1.7 5.1 9.5 8.0 11.5 4.6 2.4 8.0 0.6 5.3 7.1 5.3 2.5 10.7 8.2 4.7 4.4 16.8 3.7 7.9 6.1 5.2 3.0 4.7 9.3 2.6 1.8 1.0 7.7 13.4 1.0 4.5 3.4 10.9 5.0 4.5 3.0 4.8 5.1 4.3 5.9 12.4 0.0 6.7 5.6 4.6 1.5 3.8 1.8 0.5 1.4 8.3 9.0 3.8 ZNF684 MGC27466 ENSG00000117010 "Zinc finger protein 684" Q5T5D7 1 40531573-40548167 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 36.0" "Low region specificity" "Detected in all" HPA059153 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol Nucleoplasm "HPA059153: AB_2683932" "unprognostic (4.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-4)" "unprognostic (2.29e-2)" "unprognostic (2.96e-2)" "unprognostic (3.67e-4)" "unprognostic (8.49e-2)" "unprognostic (2.26e-3)" "unprognostic (2.10e-2)" "unprognostic (7.00e-2)" "unprognostic (4.14e-3)" "unprognostic (3.96e-2)" "prognostic favorable (4.89e-10)" "unprognostic (4.76e-3)" "unprognostic (7.11e-2)" "unprognostic (5.98e-2)" "unprognostic (1.52e-2)" 2.4 3.7 1.7 2.2 2.6 6.4 3.0 2.0 3.3 1.7 2.2 2.8 2.3 2.4 2.8 1.7 1.7 2.4 7.7 1.5 1.8 6.9 12.4 2.5 3.3 2.3 2.2 2.6 2.6 3.3 1.2 1.5 2.6 1.8 3.4 2.1 2.5 1.4 3.3 2.9 1.9 2.3 1.4 3.1 3.2 3.2 2.3 3.4 3.8 2.8 2.7 1.7 1.4 3.9 2.9 0.9 3.6 4.8 3.2 4.8 2.1 2.6 2.5 3.2 5.4 1.7 3.7 5.0 2.1 1.7 2.1 3.5 3.6 2.7 4.9 4.4 6.3 5.4 3.2 4.9 1.7 5.7 5.7 3.0 1.0 3.8 1.5 1.8 4.6 4.0 2.9 6.9 4.5 0.9 8.6 6.6 8.8 1.3 2.8 4.1 10.3 3.6 4.7 2.5 2.5 4.4 4.7 4.5 5.2 4.7 2.0 36.0 2.8 2.9 6.3 3.1 5.1 5.8 4.8 5.9 2.6 5.9 4.8 4.1 1.9 1.0 3.0 4.1 1.6 3.5 2.0 1.7 1.2 1.5 1.3 2.6 1.0 1.9 2.2 1.9 2.6 1.3 1.7 2.6 2.0 3.3 1.5 1.8 2.3 2.2 2.6 1.4 2.3 3.9 4.9 6.4 3.2 10.4 6.8 2.3 1.6 2.2 4.6 3.4 2.0 2.8 13.0 5.7 2.9 7.3 0.0 1.2 7.2 3.2 17.6 5.7 6.5 1.6 3.2 5.0 1.2 4.2 7.8 14.7 2.5 4.2 1.5 1.8 2.5 4.6 4.2 15.8 4.8 3.3 7.9 2.2 4.1 4.2 2.3 3.7 2.5 4.2 8.8 5.6 6.3 4.3 4.1 12.5 16.1 6.4 2.0 3.0 3.2 1.0 1.1 17.3 4.3 2.6 0.0 5.8 4.8 8.7 4.6 1.7 1.3 0.0 5.9 5.3 3.2 1.5