Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 556.3;vagina: 204.8" "Cell type enriched" "Detected in some" 6 "Squamous epithelial cells: 127.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 10.9;hTCEpi: 5.5;SK-BR-3: 13.9" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" 0.2 0.1 2.1 0.0 2.1 0.2 4.1 0.8 2.4 116.5 0.6 0.1 0.0 0.5 0.4 556.3 0.7 0.2 0.4 2.0 2.2 0.1 0.3 0.1 0.2 1.8 3.1 0.4 0.2 0.8 1.4 0.7 1.3 0.6 0.0 0.7 99.0 0.0 0.3 72.0 0.1 0.1 1.7 0.1 0.7 5.0 4.3 3.0 0.1 0.0 51.5 1.1 204.8 1.5 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.0 2.5 10.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 13.9 0.0 1.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 2.1 2.1 0.8 2.4 2.0 2.2 1.8 3.1 1.3 1.7 4.3 1.5 0.0 0.0 0.0 20.2 0.0 0.4 0.5 1.0 1.8 0.7 0.3 0.1 0.7 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.4 4.4 0.9 0.3 0.0 0.0 4.9 0.0 0.5 0.4 0.0 11.9 0.0 0.8 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.0 0.0 0.0 1.2 0.0 2.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.3 0.0 0.4 0.3 1.0 0.4 127.6 12.6 0.1 0.1 1.9 0.0 8.2 ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Supported Peroxisomes NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" 7.7 8.8 5.8 6.4 5.2 4.4 12.2 3.8 7.2 9.5 5.9 8.4 8.9 5.6 4.3 26.6 6.6 5.9 16.2 5.3 4.9 6.5 14.9 7.2 6.6 5.9 4.6 7.5 12.0 7.1 4.5 8.4 4.7 10.5 6.3 3.8 15.4 8.4 6.4 12.5 8.9 11.4 4.2 5.3 10.1 2.9 5.0 4.6 8.5 5.6 8.5 10.1 13.7 7.1 8.9 9.6 10.5 14.1 11.0 18.7 17.2 11.1 15.1 18.5 16.1 4.8 11.7 11.9 11.7 22.8 25.0 5.4 4.6 14.4 14.3 4.1 4.5 5.2 8.2 14.8 18.3 10.7 9.4 18.9 12.1 16.7 6.5 13.3 22.1 13.1 7.0 10.6 16.1 8.2 11.4 15.6 5.9 11.3 16.4 11.8 17.3 14.3 11.2 12.4 5.1 11.7 14.2 7.2 7.3 8.6 7.2 14.9 21.7 18.2 5.9 7.5 11.8 7.9 5.6 5.4 23.2 13.1 11.8 0.1 13.2 3.3 6.1 15.2 6.3 5.4 7.1 7.8 17.8 4.9 6.5 6.7 3.1 9.5 14.4 21.4 10.4 9.4 5.8 5.2 3.8 7.2 5.3 4.9 5.9 4.6 4.7 4.2 5.0 7.1 6.2 6.4 5.9 14.7 4.8 4.5 7.6 12.3 8.6 8.2 11.6 7.6 9.4 10.0 9.8 11.0 33.3 23.9 7.7 10.9 3.9 17.3 4.4 13.1 4.2 5.6 1.8 3.0 13.2 13.7 9.3 6.6 10.2 10.0 0.0 21.7 4.6 14.2 10.2 1.7 14.2 4.9 14.2 4.1 4.4 3.3 6.8 5.3 5.4 6.5 7.6 3.8 2.1 12.5 14.5 16.9 7.4 11.3 5.6 9.1 18.3 8.2 11.2 18.6 0.0 3.8 6.9 2.4 2.3 14.1 5.8 74.6 6.0 6.0 7.5 11.4 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 AL031777.2 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.1;Extravillous trophoblasts: 6.7;Hofbauer cells: 9.1;Syncytiotrophoblasts: 20.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 16.9;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Cell line enhanced" "Detected in some" "K-562: 6.9;SiHa: 7.7;T-47d: 4.6;U-2 OS: 5.1;U-266/70: 9.3;U-266/84: 5.6" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA041189: AB_2677357" 0.6 0.3 0.5 0.2 0.6 1.5 1.1 1.3 1.2 2.0 1.6 0.7 0.3 0.1 0.0 3.4 0.4 0.1 0.4 0.6 0.5 0.8 1.9 2.2 0.3 1.2 0.8 0.4 0.1 0.1 0.3 0.3 1.1 2.5 0.3 0.1 0.5 0.0 0.0 0.8 0.6 0.1 1.0 2.0 0.5 0.7 1.0 0.8 0.4 0.0 0.1 0.4 2.4 1.4 0.2 0.7 0.2 0.7 1.5 0.1 0.5 0.6 0.1 1.2 0.4 0.2 0.5 0.1 2.0 0.1 0.5 1.4 0.1 0.0 0.2 2.6 0.2 0.4 2.1 0.3 0.1 0.1 0.9 1.0 0.0 0.1 0.3 0.2 0.0 0.6 6.9 1.5 0.0 1.0 0.1 0.4 0.2 2.6 1.6 0.2 0.1 3.0 0.0 0.0 0.6 0.2 7.7 0.5 0.3 0.3 4.6 0.0 0.0 0.7 5.1 0.0 0.0 9.3 5.6 0.7 0.0 1.9 0.7 16.9 0.6 5.1 1.6 0.7 3.6 2.1 0.8 1.1 2.3 4.7 0.8 0.5 30.6 0.9 1.5 5.2 2.3 1.1 0.5 0.6 1.3 1.2 0.6 0.5 1.2 0.8 1.1 1.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.8;skin 1: 30.9;stomach 1: 46.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 37.2;Distal enterocytes: 38.2;Gastric mucus-secreting cells: 49.5;Paneth cells: 51.5;Squamous epithelial cells: 35.8;Suprabasal keratinocytes: 102.9;Urothelial cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cell line enhanced" "Detected in some" "A-431: 8.6;CAPAN-2: 26.1;HL-60: 9.4;NB-4: 8.7;OE19: 20.9;RT4: 16.4;T-47d: 12.2;U-937: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012922: AB_1844838" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (9.73e-3)" "prognostic favorable (8.73e-6)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (4.57e-2)" "unprognostic (7.21e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.09e-3)" "unprognostic (1.05e-2)" "unprognostic (4.87e-3)" "unprognostic (4.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.01e-3)" 0.2 0.3 0.6 9.5 0.7 5.4 2.6 0.5 0.9 7.6 0.4 7.2 2.7 0.2 0.3 33.8 0.3 3.2 0.1 0.5 0.7 4.7 2.0 1.5 4.2 1.3 0.8 0.3 12.9 0.8 0.3 0.2 1.1 2.5 7.1 0.1 4.9 0.1 0.1 30.9 2.1 1.6 0.6 6.4 46.3 0.1 0.7 5.5 0.1 0.0 7.8 4.8 13.9 0.9 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.0 0.0 6.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.6 8.7 0.0 20.9 0.1 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 1.3 0.0 0.0 12.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.9 0.0 0.0 2.1 1.1 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 6.4 0.2 0.6 0.2 0.0 0.6 0.6 0.7 0.5 0.9 0.5 0.7 1.3 0.8 1.1 0.6 0.7 0.9 0.0 0.0 3.7 0.0 1.0 37.2 18.6 7.6 1.8 0.0 1.5 0.9 0.2 5.7 4.5 7.3 0.0 0.0 0.0 38.2 0.0 3.2 0.0 0.9 0.5 0.3 1.8 0.4 0.0 5.9 0.0 0.6 49.5 4.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 14.9 16.2 9.3 3.1 0.2 0.3 8.5 1.8 0.0 2.2 0.0 0.0 0.0 0.0 5.7 51.5 0.0 0.2 10.1 0.6 0.0 1.7 0.0 0.0 0.1 0.3 0.1 0.2 35.8 102.9 0.0 0.8 0.1 25.7 30.3 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893082-49897054 "Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 716.1;Suprabasal keratinocytes: 673.3;Urothelial cells: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 310000 "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002778: , CAB079914: AB_2539861" "unprognostic (1.21e-1)" "unprognostic (2.75e-3)" "unprognostic (1.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.83e-1)" "unprognostic (4.12e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.10e-5)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" 32.1 25.3 13.4 43.6 14.2 83.1 32.6 15.2 15.3 35.7 16.3 53.4 46.4 21.7 26.6 108.2 28.3 32.8 18.3 11.8 14.3 29.7 46.1 31.5 62.0 14.7 14.3 15.3 24.7 20.4 12.6 36.3 15.4 32.2 51.0 13.2 36.3 19.2 26.1 66.0 51.2 23.8 15.6 49.6 46.7 15.8 15.9 45.2 21.1 17.1 66.7 46.8 55.7 15.6 141.5 58.2 38.4 44.8 51.5 68.4 78.3 86.5 62.6 60.3 62.2 42.6 96.2 91.3 43.7 72.7 46.3 101.7 43.7 69.3 71.3 181.4 34.9 47.2 30.6 38.3 58.1 87.2 60.7 53.7 81.5 48.9 93.7 72.1 67.6 58.3 45.9 176.9 84.7 101.5 77.7 76.5 42.0 75.9 82.8 59.4 50.1 53.9 157.6 112.9 56.4 37.4 68.9 102.3 89.0 46.5 78.0 70.0 90.0 111.9 57.4 66.7 66.1 94.3 104.4 68.6 40.1 50.9 81.3 34.2 20.7 21.1 34.7 33.0 37.6 33.5 33.7 35.3 23.9 26.6 23.0 29.6 14.7 29.1 31.4 15.8 36.2 23.4 13.4 14.2 15.2 15.3 11.8 14.3 14.7 14.3 15.4 15.6 15.9 15.6 102.9 51.3 29.9 2.9 233.7 599.8 529.1 47.9 231.6 22.9 154.4 80.1 18.5 127.2 47.6 101.2 2.1 152.7 298.8 276.0 158.5 125.4 5.8 95.6 98.5 117.1 99.3 140.1 5.3 80.0 208.1 94.9 115.7 143.7 79.9 40.3 108.5 143.3 168.0 33.7 5.9 167.0 20.3 195.6 716.1 8.3 33.5 184.5 304.1 15.0 204.9 42.2 192.6 6.0 8.9 130.4 161.6 32.7 182.4 443.4 190.8 166.5 30.3 21.6 46.0 68.8 90.7 62.7 48.7 361.4 673.3 202.9 311.0 52.6 182.5 703.8 ARHGAP27 "CAMGAP1, FLJ43547, SH3D20, SH3P20" ENSG00000159314 "Rho GTPase activating protein 27" Q6ZUM4 17 45393902-45434421 "Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.1;Paneth cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 16.7;OE19: 20.5;RT4: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023919, HPA053053" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA023919: AB_2059402, HPA053053: AB_2682027" "unprognostic (9.80e-2)" "unprognostic (1.36e-1)" "unprognostic (7.34e-2)" "unprognostic (4.89e-3)" "unprognostic (4.66e-1)" "unprognostic (2.69e-2)" "unprognostic (7.69e-2)" "unprognostic (6.89e-2)" "unprognostic (2.26e-1)" "unprognostic (2.33e-1)" "unprognostic (1.49e-2)" "unprognostic (1.96e-3)" "unprognostic (5.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.21e-4)" 16.2 7.3 4.3 8.6 6.7 11.6 15.8 4.0 4.8 27.1 3.1 39.6 10.5 8.7 1.7 98.0 11.7 3.2 22.7 3.7 4.0 20.4 6.5 28.4 9.1 5.4 4.5 3.6 7.7 3.1 10.4 4.0 4.7 17.0 8.9 0.5 37.7 1.5 4.4 27.3 51.6 2.4 4.4 63.0 12.7 8.9 5.5 6.3 16.7 1.8 6.7 17.6 44.2 4.3 6.1 6.0 0.1 1.7 0.8 0.4 16.7 0.0 0.3 0.4 0.1 5.3 11.9 5.5 11.4 0.4 2.6 3.8 0.8 1.1 0.2 11.3 3.7 0.3 2.7 3.5 0.1 0.0 15.7 0.8 4.7 0.0 1.7 0.5 3.6 5.9 1.5 9.8 0.5 4.2 5.3 1.9 0.3 20.5 4.9 4.4 0.2 1.9 3.9 26.1 0.8 0.5 0.7 5.0 0.3 2.0 3.9 10.2 5.6 0.0 1.4 0.1 0.5 12.0 8.4 1.2 0.3 1.5 0.1 1.0 5.2 4.4 2.4 8.6 1.5 3.6 1.5 2.7 4.3 2.7 1.2 1.3 10.0 1.8 11.4 7.2 2.1 4.0 4.3 6.7 4.0 4.8 3.7 4.0 5.4 4.5 4.7 4.4 5.5 4.3 19.9 6.4 17.8 2.9 23.1 10.3 15.2 9.3 2.8 3.3 11.4 7.4 10.6 15.7 13.0 18.4 4.2 7.7 38.0 99.1 3.9 6.0 1.1 11.0 2.5 20.8 19.2 1.7 3.6 3.4 11.5 3.1 31.6 18.4 4.5 0.5 17.5 2.1 15.0 1.7 8.8 34.2 10.2 47.1 13.4 1.1 0.3 33.1 7.2 19.7 26.0 1.6 23.7 3.0 2.5 19.1 79.6 0.0 15.9 28.3 57.0 6.4 11.7 1.6 0.0 3.0 2.9 6.7 2.0 9.7 8.7 14.1 14.2 1.0 43.4 57.4 ARNTL2 "bHLHe6, BMAL2, CLIF, MOP9, PASD9" ENSG00000029153 "Aryl hydrocarbon receptor nuclear translocator like 2" Q8WYA1 12 27332854-27425289 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.1;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 45.6;Excitatory neurons: 78.8;Pancreatic endocrine cells: 86.9;Prostatic glandular cells: 109.0;Urothelial cells: 128.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 6.4" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 121.9;U-2197: 159.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059074 Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nucleoli" "HPA059074: AB_2683897" "unprognostic (6.86e-2)" "unprognostic (6.16e-2)" "unprognostic (5.88e-3)" "unprognostic (1.01e-2)" "unprognostic (3.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.84e-3)" "unprognostic (2.97e-3)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (5.29e-6)" "unprognostic (5.26e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (7.81e-3)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" 3.0 1.0 1.3 10.0 6.4 2.3 2.1 0.0 3.6 5.8 0.0 2.5 2.8 1.2 0.2 28.1 0.9 3.6 0.8 2.8 1.6 1.1 4.7 2.3 5.2 0.0 0.5 0.2 1.3 1.5 0.8 2.8 0.0 1.1 3.2 0.4 7.2 0.6 0.2 7.6 2.6 4.6 0.0 1.0 10.9 2.7 0.6 4.4 0.6 0.8 22.2 14.7 11.9 2.2 76.0 19.2 4.2 1.6 3.6 11.0 58.3 26.3 34.5 16.8 26.2 18.2 57.4 0.6 14.4 12.6 51.9 30.6 12.3 92.1 42.7 121.9 15.7 14.6 11.7 15.2 4.8 29.6 6.1 4.0 8.1 58.8 45.6 28.9 80.0 17.7 7.5 29.8 19.6 9.2 16.2 16.2 32.1 25.7 65.8 29.8 68.2 4.7 14.1 42.8 13.6 2.2 13.5 2.1 0.4 10.0 2.9 9.7 54.6 54.2 31.4 159.5 110.0 4.4 8.4 0.1 46.5 23.5 10.9 1.3 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 1.3 6.4 0.0 3.6 2.8 1.6 0.0 0.5 0.0 0.0 0.6 2.2 2.1 3.2 1.3 1.3 0.4 0.8 45.6 8.6 1.2 0.9 1.6 0.8 0.9 11.5 7.5 9.2 0.0 1.9 0.3 1.5 0.0 22.1 3.8 7.9 0.7 6.9 1.2 3.4 78.8 27.4 4.0 3.2 28.1 11.8 0.0 5.3 2.5 3.5 1.4 0.0 24.8 3.3 2.0 2.5 5.4 4.4 0.0 2.9 1.8 7.5 15.7 0.0 0.0 8.5 2.3 86.9 1.4 0.0 3.4 109.0 1.7 0.6 2.7 0.1 0.0 1.7 3.6 3.1 4.7 6.6 2.3 4.2 1.3 0.2 2.1 128.2 ARPC2 "ARC34, p34-Arc" ENSG00000163466 "Actin related protein 2/3 complex subunit 2" O15144 2 218217141-218254356 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001994, HPA008352, HPA052703" Approved Supported Nucleoplasm NA NA 6600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "CAB001994: , HPA008352: AB_1854887, HPA052703: " "unprognostic (7.42e-2)" "unprognostic (4.07e-1)" "unprognostic (1.50e-1)" "unprognostic (3.28e-3)" "unprognostic (2.77e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" 205.4 121.8 114.0 361.4 125.6 544.1 163.5 109.4 130.8 163.1 117.4 252.8 200.3 153.3 161.8 460.5 146.3 211.3 167.3 135.2 123.1 155.0 152.8 259.7 505.2 115.1 114.7 121.3 122.1 115.4 94.7 295.0 116.4 132.1 274.8 77.4 163.6 176.0 385.3 293.4 226.5 291.2 117.8 294.6 251.5 149.7 118.2 298.3 115.3 250.8 626.0 402.0 231.7 125.4 438.3 188.3 264.1 198.0 346.6 463.6 489.4 680.5 640.7 551.2 549.5 588.6 452.0 358.6 347.6 764.7 396.8 492.3 362.6 985.4 645.4 284.2 296.5 362.1 279.0 325.8 386.8 764.2 968.9 310.2 784.1 552.0 454.6 515.1 731.3 294.1 179.5 681.4 858.6 304.3 416.8 888.6 310.8 500.8 201.1 307.2 235.0 488.7 556.8 787.8 156.3 278.8 246.7 265.8 590.0 544.4 192.7 689.2 642.1 709.5 268.1 321.9 507.8 359.8 418.8 624.7 515.1 472.9 548.2 1728.0 1318.5 1975.5 930.7 1773.7 626.1 785.9 720.7 913.6 1330.1 658.5 505.7 750.0 2200.3 698.9 2060.4 734.3 1039.0 2503.2 114.0 125.6 109.4 130.8 135.2 123.1 115.1 114.7 116.4 117.8 118.2 125.4 334.8 285.2 326.6 21.2 506.7 928.5 691.0 1140.2 425.2 89.8 150.3 189.7 145.3 200.1 465.4 172.9 56.3 944.5 902.3 595.0 342.4 585.8 604.0 220.6 288.5 363.5 319.7 144.9 48.5 658.7 1509.4 301.7 242.6 222.4 414.5 600.6 281.3 98.4 1094.0 58.9 33.1 329.4 364.2 779.9 1321.0 759.3 214.0 896.1 414.4 53.4 1721.9 175.3 1336.7 30.7 33.7 919.8 604.5 326.5 529.9 762.7 510.9 342.8 249.6 95.3 302.4 131.6 571.2 324.4 227.9 645.2 970.6 1045.8 694.1 285.6 337.6 1126.5 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106621 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: AB_2686124" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 9.0 5.9 3.8 5.7 4.2 9.9 6.8 4.9 5.0 7.5 3.3 7.3 3.7 6.4 4.3 10.3 6.0 6.5 5.3 3.6 5.0 5.6 9.6 6.8 7.7 6.2 5.7 7.1 4.5 6.4 4.0 7.0 6.2 6.0 6.8 3.9 5.8 5.5 3.3 12.9 4.8 8.6 4.3 5.6 5.2 9.3 4.3 8.0 5.9 5.9 9.8 9.0 8.0 4.9 8.6 16.7 14.6 13.6 20.9 20.1 28.4 9.7 15.4 11.9 16.5 12.3 23.2 17.6 18.5 15.8 14.1 14.6 11.6 21.0 26.3 20.0 3.5 7.4 8.0 18.2 17.3 13.5 12.6 16.5 18.1 20.9 21.8 15.9 18.7 19.4 10.1 12.5 18.2 33.1 14.0 11.9 10.4 28.5 13.6 11.0 27.0 9.9 15.3 19.4 5.3 8.8 23.1 9.5 13.3 19.6 18.1 9.1 10.0 11.7 17.0 7.5 5.2 10.8 19.8 16.2 8.3 12.9 6.9 13.5 14.3 10.8 6.1 16.5 7.4 7.7 7.0 6.9 16.2 10.6 7.8 8.8 12.2 8.7 23.0 9.3 8.1 6.3 3.8 4.2 4.9 5.0 3.6 5.0 6.2 5.7 6.2 4.3 4.3 4.9 55.0 16.0 12.4 33.6 27.6 25.4 28.6 29.8 19.4 35.4 16.9 18.4 19.3 15.7 20.0 42.3 50.1 20.3 31.5 13.8 15.6 25.8 19.8 20.3 34.9 53.0 16.1 30.3 36.1 17.3 29.8 34.6 18.3 22.5 24.6 25.9 49.6 21.1 22.4 26.9 28.6 16.4 12.2 35.1 27.2 26.8 67.7 30.0 23.2 28.1 48.0 20.4 29.9 39.2 51.5 19.6 16.1 65.1 20.1 31.9 16.6 17.7 16.0 46.7 46.0 51.9 38.2 39.1 57.2 21.6 30.3 25.3 28.8 24.8 18.9 28.2 BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 128.5;Breast glandular cells: 50.4;Squamous epithelial cells: 136.4;Suprabasal keratinocytes: 82.5;Urothelial cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 163.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" 0.3 0.0 0.1 1.3 0.3 0.0 14.9 1.1 0.3 24.2 5.5 7.0 17.9 0.1 0.2 158.0 16.7 4.7 0.2 0.3 0.4 5.4 0.0 0.3 0.7 3.0 1.6 0.0 10.3 0.3 1.7 3.6 3.2 4.8 4.9 0.2 131.4 0.6 2.2 34.8 13.0 0.2 1.8 0.0 6.4 2.4 0.4 0.4 0.3 39.3 8.8 0.4 72.2 2.9 23.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 0.0 1.0 20.9 0.0 5.1 0.0 163.7 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 3.9 0.0 6.2 0.0 0.0 0.0 20.6 0.9 0.0 0.0 39.8 0.0 0.3 0.2 0.0 0.0 19.4 0.1 0.4 3.8 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.3 0.3 0.4 3.0 1.6 3.2 1.8 0.4 2.9 0.2 0.0 1.1 0.3 0.5 43.1 128.5 8.7 3.4 0.6 50.4 16.9 0.5 4.3 8.0 0.0 0.0 13.4 0.8 29.4 7.9 23.7 7.2 11.3 0.6 1.2 1.8 0.0 1.8 0.7 5.8 2.7 6.6 4.6 0.0 0.0 0.0 0.2 1.9 0.0 0.3 13.4 0.0 0.3 2.2 1.6 0.0 0.7 10.6 0.0 0.1 0.7 0.0 0.0 0.3 6.2 29.8 0.4 0.9 25.6 34.0 3.4 11.8 0.3 0.0 0.6 1.7 0.1 5.3 136.4 82.5 4.2 1.7 0.0 19.4 84.8 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42101119-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 157.0;skin 1: 73.6" "Cell type enhanced" "Detected in many" "Late spermatids: 163.8;Pancreatic endocrine cells: 219.9;Prostatic glandular cells: 144.6;Urothelial cells: 226.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 57.8;CACO-2: 52.0;CAPAN-2: 44.0;OE19: 181.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" 3.7 1.0 0.4 2.2 0.4 1.0 8.7 0.6 0.7 31.7 0.3 14.1 33.4 1.0 0.1 157.0 5.8 6.6 1.8 0.4 0.1 14.9 0.5 5.8 0.3 0.4 0.1 0.2 18.0 2.5 1.7 1.5 0.4 12.1 11.7 0.9 47.1 2.3 0.9 73.6 20.7 0.5 0.0 0.1 36.2 0.7 0.3 0.7 10.7 0.3 13.9 9.9 54.9 0.6 57.8 0.5 0.0 0.1 0.3 6.1 29.0 2.9 4.4 7.6 7.6 52.0 44.0 0.0 5.4 5.4 0.1 37.5 0.1 17.3 5.2 5.1 7.2 2.8 5.0 12.1 2.0 0.0 0.2 4.0 30.4 5.9 8.8 3.1 0.0 0.3 1.7 0.5 1.7 20.4 0.4 0.3 3.6 181.7 1.5 0.1 0.0 0.3 6.2 25.5 3.0 0.1 4.7 35.2 0.1 4.1 25.2 0.3 0.8 0.4 3.5 13.5 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.1 0.4 0.4 0.6 0.7 0.4 0.1 0.4 0.1 0.4 0.0 0.3 0.6 0.8 44.8 16.6 0.3 0.2 52.5 88.6 31.8 19.4 0.8 41.7 19.8 5.1 45.8 63.1 51.5 20.9 12.4 1.2 89.9 0.0 57.9 22.2 91.9 9.4 2.8 7.3 0.0 0.5 134.7 1.0 9.2 57.1 135.8 1.3 18.3 1.4 0.0 0.8 5.0 0.5 41.3 38.7 1.2 6.8 163.8 0.6 1.5 12.4 0.0 3.8 0.5 4.1 0.5 0.2 219.9 66.8 1.5 0.3 144.6 102.7 7.7 92.1 7.9 0.0 7.9 4.9 4.9 9.1 81.4 82.0 4.1 1.5 45.4 43.7 226.0 CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enriched" "Detected in some" 8 "Squamous epithelial cells: 1257.1" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 21.5;hTCEpi: 8.6;RPMI-8226: 6.0" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" 0.5 0.1 0.2 0.0 0.2 0.0 5.4 1.5 0.1 107.9 0.0 0.1 0.0 0.1 0.1 507.1 1.2 0.0 0.1 0.0 0.3 17.3 1.6 0.0 0.0 0.5 0.3 0.1 0.2 0.0 0.3 0.0 0.2 2.9 0.0 0.0 121.0 0.1 1.0 179.0 0.2 0.0 0.0 0.1 0.3 1.7 0.7 79.5 0.1 0.0 39.8 0.2 200.8 0.0 21.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.1 0.0 0.3 0.5 0.3 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 28.4 29.8 6.3 157.1 2.2 13.3 22.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 4.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 28.5 0.0 1.4 8.3 0.3 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.5 0.0 59.6 0.7 0.3 0.0 0.0 0.9 6.7 0.1 1257.1 55.0 0.0 0.7 0.0 0.2 30.6 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPN14 ENSG00000214711 "Calpain 14" A8MX76 2 31173056-31233858 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "esophagus: 144.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.2;Inhibitory neurons: 4.2;Squamous epithelial cells: 8.2;Urothelial cells: 15.5" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 1.1;U-266/70: 3.4" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.81e-3)" "unprognostic (1.20e-1)" "unprognostic (4.57e-2)" "unprognostic (1.88e-2)" "unprognostic (3.85e-2)" "unprognostic (3.30e-1)" "unprognostic (3.61e-2)" "unprognostic (4.67e-2)" "unprognostic (1.71e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" "unprognostic (1.60e-1)" "unprognostic (3.71e-4)" "unprognostic (8.42e-2)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (4.47e-4)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 144.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.5 0.1 0.6 0.8 0.1 0.0 1.7 0.0 0.7 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.6 0.8 0.1 0.2 0.0 0.0 3.2 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 1.7 4.2 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.5 0.5 0.0 2.2 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.2 8.2 0.0 1.4 0.1 0.0 0.1 15.5 CAPZA1 ENSG00000116489 "Capping actin protein of muscle Z-line subunit alpha 1" P52907 1 112619805-112671616 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB045963 Approved NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB045963: AB_11126023" "unprognostic (7.06e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-3)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (1.17e-3)" "unprognostic (3.15e-2)" "unprognostic (3.82e-3)" "unprognostic (4.59e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (2.42e-1)" "unprognostic (2.82e-1)" 73.7 49.1 42.5 115.3 43.6 156.4 55.7 46.4 51.7 48.3 45.7 86.1 67.9 43.1 61.5 96.3 42.9 59.1 27.9 40.5 49.7 41.1 73.1 65.4 154.0 51.6 49.3 30.6 35.5 39.6 21.4 85.4 51.2 42.4 95.0 37.2 38.5 37.4 25.4 92.4 70.8 63.9 49.1 105.2 70.9 71.1 50.6 118.2 48.1 22.1 187.7 97.3 52.8 57.5 308.0 88.9 148.4 120.7 180.6 207.9 186.5 237.7 245.3 236.7 210.9 120.7 126.9 319.6 174.8 277.6 108.0 142.6 199.9 251.3 293.4 245.5 100.2 279.0 141.8 148.7 212.8 507.3 376.5 224.6 186.5 230.7 219.2 140.5 268.1 143.2 287.3 191.6 335.6 177.2 262.8 222.6 146.3 179.7 180.3 192.5 292.0 158.8 207.9 221.3 102.2 109.6 274.3 246.9 192.6 118.2 127.8 441.6 305.8 192.8 191.6 317.7 292.2 135.0 134.2 359.8 331.4 381.5 450.4 396.9 254.5 319.7 172.1 385.9 194.5 198.3 188.8 209.1 207.9 145.0 105.4 171.0 524.7 145.9 434.0 164.6 252.5 369.9 42.5 43.6 46.4 51.7 40.5 49.7 51.6 49.3 51.2 49.1 50.6 57.5 59.5 28.9 49.0 59.4 186.0 180.9 73.7 87.4 63.2 31.2 73.3 35.3 22.0 54.3 69.0 101.2 25.0 138.8 194.9 152.4 92.0 94.9 380.4 62.1 95.4 78.0 61.1 104.5 48.3 111.9 206.8 72.1 59.1 86.0 92.0 48.8 83.2 74.5 233.1 43.7 47.8 101.5 52.9 320.0 361.0 210.2 57.2 211.9 122.7 54.4 236.5 33.5 125.7 55.8 73.7 168.9 135.7 55.3 137.2 105.7 89.0 88.8 71.4 31.2 65.7 42.8 79.6 166.3 67.7 110.2 237.8 184.0 196.7 73.9 110.3 147.0 CASTOR1 GATSL3 ENSG00000239282 "Cytosolic arginine sensor for mTORC1 subunit 1" Q8WTX7 22 30285117-30289622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 48.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.8;Extravillous trophoblasts: 55.4;monocytes: 45.5;Syncytiotrophoblasts: 36.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073183 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA073183: " "unprognostic (1.48e-2)" "unprognostic (1.48e-2)" "unprognostic (1.92e-3)" "unprognostic (7.40e-3)" "unprognostic (2.75e-2)" "unprognostic (2.45e-2)" "unprognostic (8.60e-2)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (3.95e-1)" "unprognostic (3.95e-2)" "unprognostic (3.32e-2)" "unprognostic (3.37e-5)" "unprognostic (9.28e-2)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (4.26e-2)" 12.7 6.4 11.5 3.3 11.3 1.5 13.3 9.9 15.8 24.7 10.1 7.3 0.6 9.1 2.5 48.0 11.1 4.3 9.3 10.6 11.0 12.3 7.5 10.9 7.2 11.0 11.8 13.8 5.5 14.5 8.6 11.0 10.4 13.5 0.6 1.2 12.0 11.9 2.7 12.3 5.9 3.3 9.9 9.3 7.8 17.2 11.5 4.8 13.1 3.1 3.4 10.3 35.2 9.9 1.5 5.9 1.8 6.2 6.6 7.3 12.6 0.5 1.5 0.9 1.0 2.1 1.4 0.5 1.9 3.5 9.4 2.9 1.8 2.4 0.1 0.9 1.4 0.4 1.1 1.7 13.5 0.5 4.5 12.9 5.4 3.0 0.5 9.4 6.1 10.8 1.3 5.2 3.5 7.6 3.4 4.0 1.0 6.2 2.8 5.0 3.2 5.0 3.5 2.0 0.4 4.2 1.8 3.8 1.4 5.5 5.8 0.7 4.8 3.6 3.8 2.3 0.4 0.4 0.4 0.3 1.7 2.2 1.3 12.2 7.6 19.5 9.8 5.1 5.9 15.6 12.9 10.4 7.6 16.3 21.4 16.0 3.0 29.2 2.6 8.2 14.8 7.5 11.5 11.3 9.9 15.8 10.6 11.0 11.0 11.8 10.4 9.9 11.5 9.9 13.6 0.0 2.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.0 5.7 0.0 0.0 1.8 7.3 0.0 71.8 2.6 0.0 9.8 6.0 0.0 1.5 1.3 2.4 0.0 0.0 0.0 2.4 55.4 3.1 0.0 4.0 2.5 2.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 45.5 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 11.6 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 36.4 1.5 2.6 0.0 0.0 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CLDN17 "MGC126552, MGC126554" ENSG00000156282 "Claudin 17" P56750 21 30165565-30166805 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 2.3;esophagus: 6.1;salivary gland: 6.4;vagina: 7.2" "Cell type enriched" "Detected in single" 4 "Early spermatids: 4.4" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045903 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA045903: AB_2679491" "unprognostic (2.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CLIC3 ENSG00000169583 "Chloride intracellular channel 3" O95833 9 136994608-136996568 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 317.0;skin 1: 122.0;thyroid gland: 109.6;vagina: 132.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 811.8;dendritic cells: 456.0;Extravillous trophoblasts: 1219.2;NK-cells: 541.7;Syncytiotrophoblasts: 2039.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 130.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 9 "plasmacytoid DC: 2635.7" "Lineage enriched" "Detected in all" 9 "dendritic cells: 2635.7" "Cell line enhanced" "Detected in many" "BEWO: 350.3;MCF7: 168.1;SK-BR-3: 65.0;T-47d: 147.2;TIME: 118.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005963 Enhanced Supported "Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" "HPA005963: AB_1078536" "unprognostic (4.30e-2)" "unprognostic (2.53e-1)" "unprognostic (3.54e-1)" "unprognostic (1.55e-2)" "unprognostic (5.42e-3)" "unprognostic (1.85e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-3)" "unprognostic (1.39e-1)" "unprognostic (3.26e-3)" "unprognostic (7.73e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.74e-4)" 8.6 0.6 0.9 1.3 1.0 4.0 2.6 1.3 1.6 75.0 1.4 1.3 0.3 1.8 4.6 317.0 1.7 0.8 8.6 0.7 1.0 1.0 1.0 38.6 4.1 1.3 0.9 0.6 0.6 0.2 2.4 41.6 1.0 3.0 0.2 0.0 37.7 1.1 1.0 122.0 1.7 0.3 0.8 6.9 7.5 0.7 1.0 7.6 109.6 1.2 20.5 2.1 132.2 1.2 28.8 0.0 0.0 0.0 0.5 1.4 350.3 2.7 1.5 1.0 0.4 3.7 14.0 0.1 22.5 24.3 0.1 12.5 0.0 1.2 0.0 0.0 0.2 0.0 20.7 4.5 3.9 0.0 0.0 1.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 168.1 0.1 0.2 0.1 58.4 5.8 0.0 0.5 0.0 0.0 0.0 0.8 0.0 45.9 65.0 0.0 0.0 147.2 0.0 118.4 0.0 4.1 2.5 0.1 0.0 0.0 0.1 0.5 0.0 0.0 2.9 0.8 2.6 232.3 2.1 99.3 2.6 32.0 143.8 9.4 5.5 6.9 120.4 10.3 283.2 2.3 2635.7 11.5 168.3 0.9 1.0 1.3 1.6 0.7 1.0 1.3 0.9 1.0 0.8 1.0 1.2 11.5 214.7 42.0 0.0 11.6 3.8 3.6 86.6 8.0 0.0 7.3 20.6 3.2 2.8 95.2 1.8 0.0 811.8 456.0 25.2 9.8 1.8 1.7 16.7 2.3 13.4 4.9 5.3 0.0 6.4 1219.2 27.0 22.4 14.4 1.3 1.8 3.6 1.1 91.6 0.0 0.0 5.6 4.1 2.2 5.9 7.8 125.6 8.5 10.6 1.9 4.9 0.0 541.7 0.0 0.0 84.6 10.4 41.8 23.7 4.5 0.7 0.4 12.0 0.0 0.0 0.2 4.4 0.0 1.0 70.2 19.5 2039.4 78.4 1.0 5.2 18.1 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 579.1;esophagus: 1822.3;vagina: 867.6" "Cell type enhanced" "Detected in some" "Ductal cells: 22.7;Pancreatic endocrine cells: 125.4;Squamous epithelial cells: 44.1;Suprabasal keratinocytes: 37.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 68.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "CAPAN-2: 5.0" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.30e-1)" "prognostic unfavorable (7.03e-4)" "unprognostic (1.56e-2)" "unprognostic (1.46e-1)" 0.6 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 579.1 0.0 0.3 0.0 0.3 0.0 1822.3 0.2 0.0 0.3 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.4 1.2 0.0 0.7 0.2 0.0 0.3 0.0 0.0 312.0 0.0 1.0 292.2 0.4 0.0 0.0 0.3 1.2 0.2 0.0 0.0 0.2 0.0 18.4 0.4 867.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.0 0.0 0.0 1.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 44.1 37.1 0.0 0.0 0.0 0.0 2.0 CRNN "C1orf10, SEP53" ENSG00000143536 Cornulin Q9UBG3 1 152409243-152414263 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5346.2;vagina: 1691.7" "Cell type enriched" "Detected in some" 24 "Squamous epithelial cells: 79.9" "Group enriched" "Detected in many" 18 "cervical cancer: 19.3;head and neck cancer: 74.0;stomach cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024343, CAB026182" Enhanced NA NA 100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026182: , HPA024343: AB_1847162" "unprognostic (1.96e-2)" "unprognostic (1.74e-6)" "unprognostic (4.20e-2)" "unprognostic (3.43e-1)" "unprognostic (6.43e-3)" 1.0 0.9 0.1 0.0 0.1 0.0 0.7 0.0 0.2 865.3 0.0 0.6 0.0 0.8 0.0 5346.2 0.7 1.1 1.8 0.1 0.1 0.6 1.4 0.4 0.0 0.1 0.1 1.2 3.0 0.0 3.5 0.0 0.1 0.8 0.0 0.0 906.9 0.0 1.4 8.2 1.2 0.1 0.1 0.9 5.0 0.8 0.1 0.0 0.6 0.0 249.8 1.2 1691.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 79.9 0.0 0.0 0.0 0.0 0.0 0.0 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "esophagus: 11304.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 5910.7;Club cells: 4352.8;Hofbauer cells: 2827.7;Squamous epithelial cells: 4910.2;Urothelial cells: 3198.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 2798.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 8700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoli "CAB047320: , HPA017380: AB_1847414, HPA058557: AB_2683755" "unprognostic (1.69e-1)" "unprognostic (3.35e-1)" "unprognostic (2.09e-1)" "unprognostic (3.05e-2)" "unprognostic (3.05e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (6.66e-5)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (3.63e-1)" "unprognostic (4.88e-1)" "unprognostic (4.24e-2)" "unprognostic (1.24e-1)" 224.3 165.6 254.1 141.6 253.6 73.8 161.9 255.4 314.6 585.8 275.2 243.8 122.9 90.1 175.0 11304.7 154.1 150.7 192.2 252.8 263.0 144.7 189.4 290.1 176.4 258.4 257.8 136.1 116.2 154.4 70.1 132.1 259.6 137.3 194.7 78.9 738.3 138.6 100.1 256.9 135.6 110.4 257.5 125.8 249.9 71.7 262.8 268.2 147.9 197.4 1484.9 611.8 1001.9 262.9 1573.6 495.5 146.3 188.1 874.5 742.6 379.6 310.1 431.0 230.7 230.6 401.6 868.6 123.0 245.8 570.1 1814.0 260.5 384.4 405.7 153.5 529.0 388.4 332.4 385.3 473.8 753.0 85.5 267.1 754.5 439.6 621.2 314.7 389.3 331.2 111.8 276.9 681.1 359.7 431.4 100.1 267.6 336.0 1052.6 791.5 169.7 80.5 1472.0 669.1 2798.2 141.8 121.6 420.2 229.2 928.8 75.7 210.4 214.0 426.3 347.7 162.7 305.5 211.8 148.5 347.4 251.1 1432.5 430.2 242.3 390.1 505.5 313.1 242.9 840.3 224.5 198.5 315.4 255.4 766.1 172.7 221.0 217.6 445.6 152.4 1322.9 93.4 406.9 475.2 254.1 253.6 255.4 314.6 252.8 263.0 258.4 257.8 259.6 257.5 262.8 262.9 210.1 176.3 298.4 43.4 140.5 385.3 460.6 5910.7 191.2 69.8 317.8 345.1 105.7 268.8 4352.8 415.6 35.5 310.4 126.5 803.9 538.1 588.4 10.4 388.8 205.1 307.8 239.3 61.4 17.0 488.2 1199.4 238.6 297.7 458.8 228.2 131.5 250.6 464.5 2827.7 67.3 18.4 308.6 1462.8 483.4 1256.2 40.8 381.1 806.9 471.4 24.4 915.9 160.6 255.4 11.1 32.4 810.9 735.6 330.2 167.7 674.3 524.9 469.9 1997.3 72.9 118.3 86.5 320.0 33.7 111.7 4910.2 596.0 402.5 202.8 170.9 367.2 3198.3 CSTF2 CstF-64 ENSG00000101811 "Cleavage stimulation factor subunit 2" P33240 X 100820359-100841520 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000427, CAB004680" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nuclear bodies" "CAB004680: AB_425385, HPA000427: AB_1078580" "unprognostic (2.02e-2)" "unprognostic (8.70e-3)" "unprognostic (3.50e-1)" "unprognostic (3.43e-1)" "unprognostic (7.00e-2)" "unprognostic (1.09e-2)" "prognostic unfavorable (8.23e-6)" "unprognostic (2.02e-1)" "unprognostic (4.82e-2)" "unprognostic (2.08e-3)" "unprognostic (5.98e-3)" "unprognostic (2.75e-1)" "prognostic favorable (1.12e-4)" "unprognostic (1.75e-2)" "unprognostic (2.90e-2)" "unprognostic (8.75e-2)" "unprognostic (2.89e-1)" 6.3 7.2 5.7 9.9 6.0 10.5 7.7 6.7 6.3 7.0 5.0 12.0 8.6 7.5 8.2 19.2 8.1 6.4 6.1 5.9 6.4 8.0 5.3 6.3 12.5 5.4 5.4 7.1 4.7 8.9 5.3 7.2 5.3 7.5 13.1 8.5 7.9 8.4 4.5 8.4 8.2 7.6 5.3 7.0 6.6 12.7 6.6 12.0 6.7 5.1 19.9 10.0 8.4 6.3 36.0 41.7 27.5 24.9 14.7 11.4 37.2 29.6 24.0 47.6 68.0 45.4 32.1 35.6 35.2 19.1 61.2 35.1 64.2 35.3 57.2 36.5 39.9 32.8 38.8 29.8 19.4 46.9 33.8 11.3 16.5 49.8 32.6 12.7 29.0 31.3 56.2 33.7 29.2 41.9 38.4 31.8 76.8 55.7 39.9 35.8 46.3 42.3 17.5 34.4 24.1 30.4 49.1 20.5 20.4 27.6 20.5 20.3 25.8 26.2 42.3 38.1 37.8 22.8 52.3 45.9 22.5 48.6 32.4 20.0 16.1 11.1 23.4 18.9 17.9 17.4 21.1 21.8 23.3 16.9 19.0 17.8 2.6 23.9 25.8 16.7 24.2 15.3 5.7 6.0 6.7 6.3 5.9 6.4 5.4 5.4 5.3 5.3 6.6 6.3 4.1 3.2 1.1 3.9 8.2 4.2 4.6 20.7 9.6 2.2 3.1 3.0 4.9 2.8 12.9 0.0 2.1 16.7 3.6 5.9 5.9 12.5 13.3 6.3 4.9 4.6 4.2 12.8 10.4 8.3 18.4 4.3 6.1 4.3 3.8 5.5 2.5 1.5 10.8 3.3 10.8 3.7 14.2 2.5 3.7 2.4 4.7 4.3 1.8 1.0 5.9 4.5 4.1 7.1 5.7 15.4 6.7 4.1 6.2 2.0 5.4 4.0 9.9 2.9 6.6 2.7 5.7 18.8 25.5 14.4 4.1 7.7 7.1 5.0 6.4 5.0 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CYFIP1 "KIAA0068, P140SRA-1, SHYC" ENSG00000273749 "Cytoplasmic FMR1 interacting protein 1" Q7L576 15 22867052-22981063 "Predicted intracellular proteins" "Cell shape, Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 253.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 23.5;intermediate monocyte: 24.9;myeloid DC: 22.0;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.0;monocytes: 24.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068106 Approved NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA068106: AB_2685955" "unprognostic (1.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.85e-1)" "unprognostic (8.20e-3)" "unprognostic (3.94e-1)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.93e-1)" "unprognostic (8.56e-2)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "prognostic favorable (4.47e-5)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-3)" 41.2 26.0 16.6 19.8 16.9 4.7 36.4 15.8 20.0 33.2 16.7 37.7 31.5 33.8 23.8 46.2 24.7 24.0 21.8 15.5 17.9 25.9 26.1 40.5 19.2 20.7 19.5 28.9 41.7 37.3 13.3 39.5 23.1 29.3 28.1 4.4 39.3 24.6 21.2 39.7 29.3 24.9 23.5 26.5 33.8 15.9 21.7 10.2 27.5 14.4 16.2 29.9 36.6 28.6 67.6 74.8 35.5 72.2 42.7 49.3 49.7 47.5 35.7 32.1 31.7 70.0 32.9 0.2 34.1 50.0 32.9 64.2 31.9 58.8 29.7 36.2 45.5 41.3 40.9 51.9 37.3 14.4 29.5 39.3 43.1 25.4 29.7 33.6 48.3 37.0 20.0 23.4 37.8 58.1 1.5 25.7 25.1 87.1 61.8 18.3 45.7 16.6 81.4 114.3 43.1 44.3 40.9 67.2 46.3 35.0 53.1 30.3 49.5 58.7 47.2 24.3 69.6 3.4 7.7 0.7 56.6 32.5 33.7 0.0 23.5 0.4 0.5 24.9 2.4 2.0 2.1 1.0 22.0 0.3 0.4 0.1 0.7 4.3 12.5 3.3 1.6 8.2 16.6 16.9 15.8 20.0 15.5 17.9 20.7 19.5 23.1 23.5 21.7 28.6 56.7 35.3 37.9 18.6 5.7 20.0 27.3 33.8 23.9 2.3 28.9 29.8 7.4 17.2 37.9 18.4 2.1 38.6 4.1 78.7 11.7 33.5 4.5 33.8 35.8 50.7 17.4 9.2 41.8 35.0 40.0 32.2 42.8 50.6 8.8 99.1 35.3 31.5 108.7 5.0 46.1 34.0 28.5 104.5 29.5 5.3 36.4 73.8 28.4 253.9 43.3 17.9 0.0 19.6 16.0 43.2 43.2 32.4 6.3 33.2 41.9 21.8 39.6 2.0 26.3 29.5 40.8 9.0 17.9 40.4 26.3 31.7 4.8 38.5 33.0 34.8 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.5;Club cells: 59.0;Excitatory neurons: 37.4;Respiratory ciliated cells: 104.6" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.6;CACO-2: 4.6;NTERA-2: 2.1;SCLC-21H: 2.7;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 11.6 3.2 8.2 0.7 8.5 0.1 14.9 5.2 10.2 37.1 2.8 1.6 1.7 2.1 2.7 14.7 9.3 1.6 8.6 8.7 12.1 5.9 10.5 8.8 1.9 4.5 5.6 1.2 1.7 1.7 3.8 1.1 5.7 8.0 1.9 2.3 31.1 2.9 4.6 7.1 1.4 1.9 4.1 0.6 22.3 4.0 9.2 1.1 5.0 4.0 9.1 3.3 7.2 6.4 0.0 0.0 0.0 0.0 2.6 0.2 0.1 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.3 0.0 0.4 0.2 2.7 0.0 0.0 0.2 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 8.5 5.2 10.2 8.7 12.1 4.5 5.6 5.7 4.1 9.2 6.4 4.4 22.4 17.0 2.3 0.0 2.5 26.9 37.5 25.0 2.4 31.0 0.9 0.8 1.5 59.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 8.4 7.6 0.8 4.0 0.0 0.0 37.4 0.7 0.0 7.1 4.1 1.4 0.0 0.0 1.1 2.8 3.9 0.0 29.3 0.2 18.3 0.6 0.7 8.6 10.5 0.5 5.4 4.7 0.0 0.1 0.0 1.0 2.0 0.1 0.0 20.7 0.0 8.4 0.5 1.7 104.6 0.8 0.0 2.0 19.1 0.5 3.6 21.4 1.4 0.1 0.5 0.1 1.9 31.8 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.6;salivary gland: 3.2;vagina: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 5.8;LHCN-M2: 1.7;U-2197: 3.0" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.6 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 124.1" "Group enriched" "Detected in some" 8 "Basal respiratory cells: 79.5;Club cells: 38.3;Exocrine glandular cells: 37.4;Pancreatic endocrine cells: 41.0" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 124.1 0.1 3.6 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 3.2 0.4 0.0 0.0 0.0 7.3 0.0 0.0 5.0 0.0 0.0 7.6 0.2 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.1 0.0 5.6 0.0 4.3 0.0 5.3 0.2 0.0 0.0 0.0 0.0 37.4 0.0 0.0 3.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.0 1.1 0.0 0.0 0.1 0.0 0.1 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.0;lymphoid tissue: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 313.9;vagina: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 197.6;Basal squamous epithelial cells: 101.9;Squamous epithelial cells: 470.6;Suprabasal keratinocytes: 206.4;Urothelial cells: 87.2" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.2" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.2" "Group enriched" "Detected in some" 7 "HaCaT: 204.4;hTCEpi: 494.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" 0.3 0.0 0.1 0.2 0.1 0.2 3.9 0.1 0.2 71.1 0.1 0.0 5.4 0.0 0.0 313.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.4 0.1 0.0 43.6 0.0 0.1 39.9 3.9 0.0 0.0 0.0 0.2 0.1 0.2 14.8 0.0 0.0 72.7 1.2 119.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 204.4 0.0 46.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 494.7 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 28.9 18.5 0.0 0.2 197.6 17.4 32.2 101.9 0.3 0.5 5.0 0.3 0.0 21.1 0.0 0.0 0.4 1.5 0.2 0.0 0.2 0.6 0.1 0.3 2.7 0.0 0.0 2.7 0.4 0.4 2.2 0.0 0.1 12.6 0.0 0.4 0.3 0.4 0.0 0.1 1.3 2.0 0.3 7.7 0.5 0.0 3.2 7.2 0.0 0.7 0.1 0.0 0.0 0.1 1.3 2.5 0.7 1.2 12.3 7.1 0.1 15.9 0.8 6.6 0.0 1.8 3.3 2.8 470.6 206.4 0.3 1.3 0.0 6.5 87.2 DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.5;skin 1: 81.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.3;Alveolar cells type 2: 168.6;Endometrial ciliated cells: 67.1;Glandular and luminal cells: 88.5;Respiratory ciliated cells: 64.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Group enriched" "Detected in many" 6 "cerebellum: 12.4;white matter: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 64.4;hTCEpi: 30.5;RT4: 36.3" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 9.6" HPA023544 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favorable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" 1.5 14.1 0.7 1.0 1.0 0.2 4.5 12.4 1.2 44.5 0.0 1.0 0.6 3.0 50.0 108.5 14.0 3.3 3.3 1.0 0.3 0.7 0.4 70.1 0.3 0.3 0.3 1.8 0.5 5.2 1.3 1.5 0.6 13.8 0.3 0.6 18.7 13.0 0.4 81.7 0.7 0.4 0.1 0.3 64.3 1.6 0.4 1.1 70.4 0.0 14.7 11.1 42.0 3.2 8.3 0.1 0.5 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 64.4 0.0 6.1 0.0 0.8 0.4 0.0 0.9 0.1 0.0 0.0 0.3 0.0 30.5 0.0 1.9 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.1 0.0 0.0 36.3 0.8 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.0 12.4 1.2 1.0 0.3 0.3 0.3 0.6 0.1 0.4 3.2 0.9 83.3 168.6 4.2 4.5 11.1 14.3 22.8 11.4 21.3 4.7 2.8 2.4 8.6 32.5 3.7 8.4 5.3 7.6 2.5 0.0 3.8 0.7 67.1 9.4 3.8 21.7 2.7 5.1 5.4 0.6 5.1 17.9 88.5 8.2 7.9 7.9 1.5 1.2 6.7 3.9 4.0 16.2 3.1 43.5 0.3 3.4 3.3 16.0 1.0 3.2 3.5 33.0 9.5 10.6 4.7 4.0 3.8 0.1 9.5 6.8 0.5 64.9 4.4 0.0 8.5 4.7 11.5 7.5 36.4 18.0 3.7 4.5 0.4 5.6 30.0 DUOXA1 "FLJ32334, mol, NIP, NUMBIP" ENSG00000140254 "Dual oxidase maturation factor 1" Q1HG43 15 45117367-45129938 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 189.0;skin 1: 91.6;thyroid gland: 111.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 118.0;Club cells: 35.5;Glandular and luminal cells: 47.7;Respiratory ciliated cells: 36.9;Squamous epithelial cells: 53.6;Urothelial cells: 44.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041578 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA041578: AB_10795691" "unprognostic (1.28e-1)" "unprognostic (1.32e-3)" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (2.71e-1)" "unprognostic (6.87e-3)" "unprognostic (1.03e-1)" "unprognostic (4.45e-2)" "unprognostic (6.69e-2)" "unprognostic (3.68e-2)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.17e-5)" "unprognostic (8.11e-2)" "unprognostic (1.12e-2)" "unprognostic (4.69e-2)" "unprognostic (5.36e-2)" 1.1 5.0 0.2 1.3 0.5 0.1 4.0 0.7 1.1 32.1 0.0 0.9 0.8 4.6 49.3 189.0 5.7 4.3 2.1 0.5 0.3 0.8 0.3 64.3 0.1 0.6 0.1 1.1 0.4 5.0 0.7 0.8 0.8 21.6 0.5 0.1 27.5 12.0 0.5 91.6 0.8 0.2 0.1 0.1 43.6 0.2 0.7 0.7 111.1 0.0 17.9 23.3 77.4 2.9 10.6 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 103.9 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 14.5 0.0 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.7 1.1 0.5 0.3 0.6 0.1 0.8 0.1 0.7 2.9 0.0 60.9 118.0 1.0 0.0 9.4 18.8 26.9 18.2 0.6 1.4 1.7 0.5 0.0 35.5 0.0 2.1 2.4 0.0 3.3 0.0 2.0 0.1 28.7 4.0 0.8 3.0 0.0 0.7 3.1 0.1 1.6 8.6 47.7 1.3 0.3 0.0 0.0 0.3 0.0 0.4 0.1 4.1 0.0 1.2 0.0 0.3 0.8 0.0 0.0 0.6 0.1 0.0 0.5 1.8 1.9 3.3 0.0 0.0 13.4 0.0 0.0 36.9 0.1 0.0 0.7 1.1 0.0 0.9 53.6 21.9 3.0 0.6 0.1 0.4 44.2 DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 29.3" "Cell type enriched" "Detected in single" 4 "Squamous epithelial cells: 1.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" 0.8 0.4 1.7 0.6 1.3 2.2 0.6 2.2 2.4 0.6 0.0 0.6 0.6 1.0 2.1 29.3 0.5 0.6 1.0 1.4 1.8 0.9 0.8 0.5 1.1 0.9 0.4 0.8 0.4 0.3 0.0 0.4 1.2 0.3 0.7 2.6 1.9 0.5 0.8 1.1 0.5 0.8 0.1 2.4 0.4 1.0 1.5 0.3 0.5 0.4 1.9 0.3 0.2 2.4 0.5 0.2 1.3 0.6 0.6 1.4 1.3 0.3 0.5 1.0 1.0 0.7 0.5 0.7 0.5 0.6 1.1 0.5 0.9 0.0 0.5 0.2 0.2 0.2 0.9 0.4 0.5 0.7 0.6 0.6 0.1 0.9 0.3 0.3 0.2 0.6 1.0 12.9 0.1 0.2 0.5 0.4 2.0 0.2 0.3 0.5 1.5 0.6 0.3 0.7 0.5 0.7 0.2 0.3 2.4 0.9 0.4 0.8 2.2 0.4 2.4 0.5 0.4 0.5 0.4 1.0 0.6 0.3 0.3 0.3 0.3 0.6 0.2 0.3 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.8 0.2 0.8 0.2 0.0 0.0 1.7 1.3 2.2 2.4 1.4 1.8 0.9 0.4 1.2 0.1 1.5 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Macrophages: 1.1;Squamous epithelial cells: 5.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 75 "T-cells: 7.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HaCaT: 10.2;OE19: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042292 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.2 0.6 0.0 1.3 1.1 0.5 0.2 3.6 0.2 0.9 0.0 0.1 0.0 0.6 0.9 0.2 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.7 1.9 0.0 0.6 0.1 0.0 1.4 1.0 0.0 0.0 0.2 0.9 0.1 0.1 1.2 0.0 0.0 1.2 1.5 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.7 0.0 0.4 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 7.5 3.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.4 0.0 0.1 0.6 0.5 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.8 0.0 0.3 0.8 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.9;vagina: 31.0" "Cell type enhanced" "Detected in some" "Adipocytes: 6.9;Glandular and luminal cells: 9.6;Squamous epithelial cells: 5.2;Suprabasal keratinocytes: 9.1;Syncytiotrophoblasts: 34.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.2;SK-BR-3: 4.9;SuSa: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" NA NA 14000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA012388: AB_1854860, HPA067448: AB_2685843" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.29e-4)" "unprognostic (6.50e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" 1.8 0.1 2.5 0.1 2.8 0.2 1.7 2.6 3.1 19.5 1.8 0.7 0.1 0.5 1.0 82.9 0.9 0.5 0.6 2.8 2.1 1.1 0.1 0.7 0.3 2.5 2.6 1.8 0.2 0.0 0.5 2.5 2.7 0.4 0.1 0.1 23.2 0.2 0.5 21.1 0.4 0.5 2.2 0.3 0.6 0.3 2.7 0.1 0.9 0.1 8.8 0.7 31.0 2.3 0.0 0.0 0.0 0.0 0.3 1.1 0.7 0.2 0.9 0.8 0.7 0.1 0.0 2.2 0.5 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 4.6 0.1 0.0 0.1 0.2 0.0 0.6 0.1 1.2 1.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.8 2.6 3.1 2.8 2.1 2.5 2.6 2.7 2.2 2.7 2.3 6.9 0.0 0.0 2.0 0.1 1.7 0.2 0.0 0.0 0.2 0.4 0.4 1.2 0.0 0.7 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.1 2.4 0.8 3.5 0.0 0.0 0.1 0.0 1.0 0.8 0.0 9.6 0.0 0.0 2.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.5 0.1 3.6 1.0 0.1 0.1 0.0 0.5 0.5 0.1 0.0 1.2 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.0 0.0 5.2 9.1 34.3 0.0 0.2 0.0 0.1 EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.0;Basal prostatic cells: 7.3;Basal squamous epithelial cells: 25.6;Urothelial cells: 5.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTCEpi: 157.9;U-2197: 74.8" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" 1.6 0.1 0.2 1.6 0.1 0.3 1.4 0.4 0.6 5.2 0.1 0.1 0.1 0.0 1.1 49.0 1.5 0.1 0.8 0.2 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.1 0.1 2.2 0.1 0.5 0.1 0.2 0.0 0.2 3.6 3.1 0.1 3.5 0.1 0.0 0.1 0.3 0.0 1.1 0.1 0.9 0.0 0.0 3.4 1.3 9.6 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.1 1.8 0.2 3.6 0.0 2.8 0.0 0.0 0.0 0.5 20.2 0.0 0.2 0.0 0.7 0.0 157.9 2.9 11.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.0 0.0 0.3 0.0 3.6 0.4 0.0 0.0 0.3 0.3 0.1 0.0 8.3 3.3 0.0 0.0 0.5 0.0 0.2 0.4 0.1 74.8 0.2 0.0 0.0 0.1 0.7 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.3 0.1 0.7 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 6.0 7.3 0.9 25.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 3.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 3.0 1.6 0.1 0.2 0.0 0.0 5.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;stomach 1: 37.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.9;Distal enterocytes: 27.6;Gastric mucus-secreting cells: 44.9;Intestinal goblet cells: 24.9;Squamous epithelial cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 28.6;HBEC3-KT: 40.3;MCF7: 66.4;OE19: 62.8;RT4: 50.2;SK-BR-3: 25.8;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" 0.2 8.9 2.3 0.8 1.3 0.6 2.3 6.4 6.0 6.5 1.2 7.1 6.8 0.4 3.2 35.9 7.5 5.9 7.1 0.7 2.1 6.0 0.1 0.3 0.0 11.5 5.4 13.5 23.0 21.2 0.8 4.2 13.6 9.9 4.4 0.2 11.1 5.6 0.1 30.5 3.2 0.1 0.5 0.0 37.3 2.8 13.4 3.2 1.1 0.0 3.7 5.5 12.9 1.8 20.5 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 14.7 12.1 0.0 0.2 0.0 0.1 28.6 0.0 40.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.1 21.8 0.1 3.0 0.0 0.0 0.1 0.0 0.0 0.0 66.4 0.3 0.0 0.0 62.8 0.4 0.0 0.0 0.1 0.2 50.2 0.4 0.0 0.0 25.8 0.0 0.4 57.4 0.2 1.5 0.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 6.4 6.0 0.7 2.1 11.5 5.4 13.6 0.5 13.4 1.8 0.2 0.0 0.0 0.0 0.4 2.3 4.4 4.1 10.8 2.9 6.5 3.4 5.4 8.6 8.3 18.4 0.0 77.9 0.0 27.6 5.9 9.2 1.0 3.8 0.6 0.4 3.6 0.0 1.0 11.5 7.4 0.8 44.9 5.5 0.0 3.1 0.0 0.0 5.9 0.0 1.7 24.9 2.0 0.0 0.0 2.1 2.8 0.5 0.0 1.0 0.6 0.6 0.0 0.0 0.0 3.4 10.3 0.0 1.3 4.9 2.1 0.3 4.3 0.9 0.0 0.0 0.8 0.0 0.5 30.0 5.5 10.7 0.2 12.4 19.3 7.8 ERO1A "ERO1-alpha, Ero1alpha, ERO1L" ENSG00000197930 "Endoplasmic reticulum oxidoreductase 1 alpha" Q96HE7 14 52639915-52695900 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 172.5" "Cell type enhanced" "Detected in many" "Ductal cells: 221.3;Extravillous trophoblasts: 215.8;Pancreatic endocrine cells: 264.7;Prostatic glandular cells: 171.4;Urothelial cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026653, HPA030053, CAB034294" Enhanced "Intracellular and membrane" NA NA 110000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB034294: AB_2098744, HPA026653: AB_1848254, HPA030053: AB_10601467" "unprognostic (8.64e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.86e-2)" "unprognostic (5.89e-2)" "unprognostic (5.69e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (7.59e-4)" "prognostic unfavorable (1.10e-5)" "unprognostic (4.98e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.54e-9)" "unprognostic (9.19e-2)" "unprognostic (2.78e-2)" "unprognostic (4.58e-1)" "unprognostic (5.03e-2)" 17.9 8.6 12.2 20.4 11.7 47.0 16.4 11.8 12.9 59.0 11.3 18.5 17.9 12.0 15.1 172.5 10.0 18.9 15.5 12.1 16.6 14.6 31.2 15.2 14.9 11.7 13.3 8.5 18.9 11.1 12.6 44.4 12.8 9.6 17.8 30.6 37.4 14.0 9.1 18.9 16.5 12.0 9.9 14.6 29.0 5.4 15.1 8.3 13.4 8.2 30.4 32.6 62.4 10.9 100.6 24.2 19.9 21.4 54.4 61.3 38.0 42.4 52.7 34.1 56.9 33.4 158.0 26.3 50.7 28.3 42.0 61.1 27.1 84.1 84.9 22.0 14.5 3.6 25.1 42.1 46.2 60.2 72.1 54.5 54.2 43.9 44.5 79.9 48.2 32.3 18.1 50.8 46.2 15.8 36.0 37.8 11.8 46.5 15.5 21.5 59.8 38.1 52.3 97.1 18.5 49.6 28.9 17.8 39.4 25.7 24.8 22.3 40.0 60.7 29.5 49.6 37.4 26.9 28.8 22.7 88.0 30.3 28.7 20.6 5.9 11.7 5.0 6.9 11.0 4.6 9.4 6.3 4.9 3.1 5.5 5.5 14.7 6.7 9.4 3.7 11.9 2.5 12.2 11.7 11.8 12.9 12.1 16.6 11.7 13.3 12.8 9.9 15.1 10.9 33.8 16.0 27.6 0.0 18.8 0.0 79.2 0.0 19.4 23.4 29.7 11.8 0.0 38.6 15.5 38.6 16.7 24.3 23.3 33.4 3.9 221.3 0.6 32.4 23.8 32.6 10.9 9.9 0.0 130.6 215.8 20.5 56.1 64.0 6.3 10.9 21.0 62.5 42.9 42.1 0.0 10.7 0.0 42.7 0.0 1.6 6.2 49.7 0.0 0.0 45.0 12.2 15.5 0.0 0.0 264.7 18.1 12.8 60.0 171.4 29.0 15.1 13.1 26.4 19.7 14.6 20.9 0.6 3.6 25.7 0.0 91.4 32.1 10.4 20.3 145.8 EVPLL ENSG00000214860 "Envoplakin like" A8MZ36 17 18377778-18389647 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 16.9;skin 1: 6.0;vagina: 8.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.1;Basal squamous epithelial cells: 8.0;Spermatogonia: 5.8;Squamous epithelial cells: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.2;HaCaT: 1.1;HeLa: 2.4;hTCEpi: 7.1;RT4: 2.5;SiHa: 1.3;T-47d: 2.1" HPA045728 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA045728: AB_10960394" "unprognostic (1.34e-1)" "unprognostic (4.88e-2)" "unprognostic (2.06e-5)" "unprognostic (1.58e-1)" "unprognostic (2.08e-2)" "unprognostic (1.64e-2)" "unprognostic (3.07e-1)" "unprognostic (3.62e-1)" "unprognostic (4.60e-4)" "unprognostic (5.28e-2)" "unprognostic (2.58e-1)" "unprognostic (1.43e-2)" "unprognostic (5.06e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.1 0.1 0.0 0.2 16.9 0.1 0.0 0.0 0.0 0.0 1.2 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.0 1.9 0.2 0.0 6.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.4 1.1 0.0 0.1 2.2 8.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 1.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.5 1.6 1.3 8.0 0.0 0.1 0.6 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 5.8 10.9 1.3 0.0 0.0 0.0 0.2 1.0 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 143.3;esophagus: 519.5;salivary gland: 140.0;skin 1: 175.0;vagina: 193.1" "Group enriched" "Detected in some" 4 "Suprabasal keratinocytes: 49.6;Syncytiotrophoblasts: 16.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 53.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A-431: 30.3;SK-BR-3: 70.0" "Low region specificity" "Detected in single" HPA044808 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA044808: AB_2679096" "unprognostic (9.94e-2)" "unprognostic (2.57e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-5)" "unprognostic (1.21e-1)" 0.3 2.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 143.3 0.0 0.1 0.0 0.1 0.0 519.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.1 1.5 0.0 0.1 0.0 0.0 140.0 0.0 1.2 175.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 1.4 0.0 0.0 63.6 0.1 193.1 0.1 30.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.3 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.0 0.2 2.0 0.0 0.3 0.0 1.6 1.2 0.0 0.0 0.0 70.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 49.6 16.1 0.0 0.0 0.0 1.9 FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 111.3;vagina: 55.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 71.2;Club cells: 58.2;Pancreatic endocrine cells: 28.7;Squamous epithelial cells: 19.3;Suprabasal keratinocytes: 15.2;Urothelial cells: 25.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 52.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 83.5;HBEC3-KT: 126.3;hTCEpi: 66.4;K-562: 206.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA052615: AB_2797244" "unprognostic (4.48e-2)" "unprognostic (2.03e-3)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.98e-9)" "unprognostic (2.62e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (2.04e-1)" "unprognostic (2.22e-16)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "unprognostic (6.07e-2)" 0.2 0.6 0.0 0.1 0.0 0.2 0.3 0.2 0.1 18.9 0.1 0.1 1.0 0.0 1.3 111.3 4.3 1.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 0.0 0.1 7.5 6.4 0.1 10.2 2.4 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.4 0.0 7.4 3.8 55.8 0.0 83.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.7 10.6 0.0 0.0 25.9 0.0 126.3 0.0 0.0 0.1 0.8 9.2 0.0 0.0 0.1 0.1 0.0 66.4 0.0 16.8 0.0 0.0 0.1 206.3 0.1 0.0 0.3 0.0 0.1 0.0 4.2 0.1 0.0 0.0 0.1 0.0 18.4 0.1 0.0 14.4 9.7 0.1 0.2 1.5 0.2 0.6 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 4.0 71.2 1.2 0.0 4.4 0.9 1.1 0.0 58.2 1.8 0.0 0.1 0.0 1.0 0.0 0.3 1.0 0.0 0.1 0.1 0.0 0.0 0.6 0.7 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 10.2 0.0 0.4 1.6 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 28.7 0.2 0.0 0.1 0.7 1.1 0.1 9.6 0.0 0.0 0.1 1.4 2.2 0.6 19.3 15.2 0.0 0.1 0.0 0.8 25.0 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Vesicles" Cytosol "HPA049390: AB_2680742" "unprognostic (9.02e-3)" "unprognostic (1.01e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (9.33e-2)" "prognostic favorable (5.44e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" "prognostic favorable (8.11e-4)" "unprognostic (9.77e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (5.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (5.09e-6)" 7.5 7.2 10.6 11.1 11.0 9.2 8.9 9.5 12.6 13.5 18.4 11.7 7.6 13.6 7.5 21.4 10.3 5.1 8.5 8.8 12.2 7.9 10.5 7.4 14.7 8.7 9.6 14.1 9.6 5.8 9.4 6.6 11.5 9.8 7.5 9.9 10.1 5.3 11.4 13.4 11.1 6.3 6.0 14.4 10.8 12.3 9.9 11.1 10.4 5.4 13.9 9.3 13.0 20.9 14.0 21.5 16.2 18.9 4.1 7.3 18.3 7.1 4.0 5.6 6.5 17.8 17.9 24.1 9.5 4.0 7.9 19.9 12.1 9.1 4.2 30.0 25.5 19.6 84.1 9.8 6.2 8.7 24.2 6.1 8.1 9.5 5.9 14.0 8.4 29.4 15.6 28.4 4.6 13.2 20.3 10.2 10.2 13.0 7.3 27.3 9.0 22.6 6.7 16.3 16.1 14.1 11.4 23.7 9.4 15.3 20.1 10.7 9.6 11.8 10.6 6.5 12.0 27.2 41.0 16.1 13.1 12.3 9.8 4.6 1.1 1.2 1.8 0.9 1.2 2.1 1.3 1.3 0.8 3.8 1.2 1.4 3.3 0.6 1.2 1.3 1.4 0.7 10.6 11.0 9.5 12.6 8.8 12.2 8.7 9.6 11.5 6.0 9.9 20.9 4.8 9.6 4.8 6.2 6.5 26.0 10.0 5.7 9.1 3.3 12.7 8.5 5.4 10.0 6.1 7.3 2.1 7.9 3.4 16.3 1.9 6.5 2.9 8.0 5.1 5.2 7.3 5.9 6.5 4.9 19.0 3.6 6.1 9.2 3.8 11.4 4.2 21.1 3.7 11.8 5.5 12.7 0.0 5.7 8.8 3.1 5.6 3.3 5.4 5.6 5.6 4.0 7.2 4.0 6.1 6.9 12.2 1.9 5.5 8.0 6.3 2.2 7.2 3.4 0.0 3.6 4.7 6.5 4.6 13.3 35.8 12.4 5.1 4.9 9.3 11.1 FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1044.3;Basal respiratory cells: 596.2;Squamous epithelial cells: 528.5;Suprabasal keratinocytes: 786.2;Urothelial cells: 303.6" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 556.3;HBEC3-KT: 968.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" 0.6 0.1 0.0 1.7 0.0 0.1 13.5 0.0 0.0 117.1 0.0 22.1 1.8 0.5 0.1 421.8 1.2 0.3 0.2 0.0 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.1 0.4 0.0 0.2 1.1 0.0 1.7 15.6 0.0 59.7 0.1 0.1 91.2 7.0 1.1 0.0 0.1 2.0 0.0 0.0 0.3 0.7 0.0 38.4 14.9 172.3 0.0 150.7 10.5 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 189.0 0.0 10.9 0.0 0.2 556.3 0.0 968.2 0.0 0.0 1.2 0.0 2.0 0.0 0.2 0.0 0.4 0.1 141.0 0.0 17.7 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 7.9 75.2 0.0 0.0 0.0 93.4 6.7 0.0 0.0 0.2 0.0 0.2 0.0 0.9 0.5 0.1 0.2 0.3 0.0 0.3 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 8.4 0.0 0.3 1044.3 182.5 596.2 217.4 0.0 11.8 3.2 0.1 0.0 223.2 0.0 0.0 0.2 0.2 49.6 0.0 49.7 0.0 52.8 3.3 6.3 0.0 0.0 0.0 7.5 2.4 6.2 0.0 65.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.1 42.7 0.0 60.6 0.0 0.0 0.9 74.7 0.0 0.6 0.0 1.0 0.0 0.0 139.1 50.8 0.0 0.0 90.8 0.7 0.0 56.8 0.0 0.0 0.0 10.4 0.0 0.0 528.5 786.2 2.3 2.1 0.0 26.1 303.6 FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 51.2;Squamous epithelial cells: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Mitotic spindle" "HPA043478: AB_2678500, HPA060158: AB_2684213" "unprognostic (1.80e-1)" "unprognostic (6.80e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-3)" "unprognostic (1.02e-1)" "unprognostic (7.67e-2)" "unprognostic (8.22e-3)" "unprognostic (2.25e-2)" "unprognostic (1.22e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-2)" "unprognostic (7.32e-2)" "unprognostic (4.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" 3.3 4.2 2.9 2.0 2.5 2.8 4.0 2.2 3.2 3.8 2.2 4.1 1.6 3.1 6.1 10.7 4.3 1.6 2.9 2.6 2.4 4.0 5.2 3.2 3.1 2.9 2.4 3.2 5.5 4.0 2.9 1.7 2.6 3.2 3.4 1.8 6.4 1.1 4.5 9.8 3.6 3.6 2.1 4.7 6.1 6.2 2.5 5.5 5.6 4.4 1.1 2.9 5.1 3.6 0.0 0.9 8.1 13.8 11.6 8.2 3.4 5.4 6.1 10.0 9.7 17.5 7.3 0.0 1.8 9.3 13.1 4.2 11.3 10.5 6.9 0.0 13.7 0.0 11.9 10.2 6.5 0.0 6.6 8.0 5.6 19.3 6.1 7.3 10.6 15.8 11.9 15.0 10.2 6.0 6.9 5.9 6.0 16.1 3.0 0.0 5.0 13.6 10.4 1.5 15.3 1.0 5.5 9.6 10.2 2.4 16.8 11.8 4.7 14.3 4.1 7.5 13.3 7.7 1.5 5.7 5.6 7.1 9.1 6.6 1.8 0.5 0.7 2.5 0.7 2.1 1.1 1.3 1.9 0.5 1.0 1.0 2.6 3.4 0.8 1.6 0.3 1.5 2.9 2.5 2.2 3.2 2.6 2.4 2.9 2.4 2.6 2.1 2.5 3.6 8.8 6.4 5.9 0.3 7.8 11.2 4.7 6.7 51.2 2.9 11.5 8.5 2.0 7.2 6.2 1.8 0.0 9.9 6.1 9.3 5.9 8.1 4.2 11.6 6.1 9.6 6.0 19.8 0.7 6.7 13.3 5.6 6.1 8.1 2.5 12.4 5.0 3.3 5.0 10.1 0.6 7.0 8.2 2.8 8.8 5.5 2.8 4.2 7.2 1.0 3.7 7.3 3.1 0.0 0.5 6.0 6.2 3.4 7.7 5.2 10.3 9.9 3.2 4.9 0.0 5.4 17.4 11.1 8.8 34.1 10.2 14.1 6.8 14.9 6.5 4.1 GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 152.3;esophagus: 171.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 169.0;Breast myoepithelial cells: 113.2;Club cells: 83.1;Endometrial ciliated cells: 146.0;Glandular and luminal cells: 464.0;Urothelial cells: 146.6" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.7" "Cell line enhanced" "Detected in many" "A-431: 215.1;EFO-21: 236.8;HeLa: 166.8;PC-3: 331.3;SuSa: 418.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB014883 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" 4.5 3.6 10.4 7.3 10.5 9.9 152.3 15.8 16.2 13.1 5.4 4.2 15.4 48.6 19.0 171.5 12.9 27.3 5.4 7.6 23.0 6.1 7.1 14.7 5.7 12.5 6.1 3.9 23.8 2.0 2.0 9.1 10.6 12.7 4.9 42.1 35.8 16.6 13.7 19.0 16.2 2.6 2.7 7.4 27.4 8.3 10.4 4.7 6.1 2.7 42.2 5.4 29.4 17.9 215.1 9.9 10.1 7.0 0.7 4.3 23.8 3.8 1.5 0.5 0.6 38.1 23.6 3.3 236.8 1.1 2.3 75.7 6.4 0.5 0.6 3.5 7.6 14.1 166.8 5.7 0.8 5.1 11.2 1.6 3.0 2.8 1.8 8.0 1.4 13.4 57.6 26.5 0.4 6.7 9.5 4.7 84.5 3.7 331.3 13.7 6.6 8.2 13.8 11.6 8.2 4.0 76.5 3.9 2.2 418.8 4.2 2.4 8.8 19.1 69.3 15.7 15.7 10.0 6.7 6.3 2.6 13.9 2.9 11.8 1.9 6.1 0.4 1.5 1.1 0.3 0.4 0.3 0.6 0.7 0.5 0.5 4.5 0.2 5.7 0.9 0.6 2.3 10.4 10.5 15.8 16.2 7.6 23.0 12.5 6.1 10.6 2.7 10.4 17.9 1.1 3.2 0.6 0.0 0.9 0.0 14.9 44.4 0.0 0.0 169.0 113.2 0.7 51.5 83.1 1.8 0.0 5.2 2.3 0.0 0.0 10.4 0.0 146.0 48.8 3.8 0.0 0.0 0.3 13.8 0.6 2.4 2.0 464.0 0.0 0.0 0.0 0.1 2.3 0.0 0.2 0.3 12.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.6 0.1 0.0 0.0 24.2 0.1 0.1 34.0 0.0 0.0 0.2 5.9 0.0 0.0 4.5 0.0 5.7 2.7 0.0 0.6 146.6 GBP6 DKFZp686G0786 ENSG00000183347 "Guanylate binding protein family member 6" Q6ZN66 1 89364059-89388160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 327.3" "Cell type enriched" "Detected in some" 25 "Squamous epithelial cells: 325.0" "Group enriched" "Detected in many" 7 "cervical cancer: 21.7;head and neck cancer: 38.1;lung cancer: 14.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "A-431: 5.4;HaCaT: 11.3" "Low region specificity" "Detected in all" HPA027744 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA027744: AB_10602809" "unprognostic (7.60e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (7.05e-3)" "unprognostic (5.85e-2)" "unprognostic (5.66e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "unprognostic (7.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.04e-6)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (3.91e-3)" 0.0 0.0 0.3 0.2 0.3 0.2 0.2 0.3 0.4 25.9 0.1 0.0 0.0 0.1 0.1 327.3 0.3 0.2 0.1 0.3 0.2 0.0 0.1 0.3 0.1 0.5 0.2 0.4 0.1 0.0 0.8 0.0 0.5 0.1 0.0 0.1 62.8 0.1 0.2 0.9 0.0 0.0 0.3 0.2 0.3 0.0 0.3 1.1 0.2 0.2 55.0 0.1 32.0 0.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 11.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.3 0.3 0.7 0.2 0.1 0.1 0.6 0.1 0.3 0.3 0.3 0.4 0.3 0.2 0.5 0.2 0.5 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 5.2 12.5 0.1 0.0 0.0 0.2 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.5 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.4 0.0 0.0 12.8 0.0 0.0 0.0 1.2 0.0 0.1 325.0 0.0 0.0 0.2 1.2 0.0 1.2 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.6;esophagus: 108.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 141.5;Langerhans cells: 190.6;Macrophages: 78.3;Suprabasal keratinocytes: 95.8;Urothelial cells: 173.8" "Group enriched" "Detected in all" 4 "cervical cancer: 39.9;head and neck cancer: 46.4;lung cancer: 17.3;pancreatic cancer: 11.9;urothelial cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.1" "Group enriched" "Detected in many" 4 "dendritic cells: 67.1;granulocytes: 19.4;monocytes: 29.1" "Cell line enhanced" "Detected in some" "HBEC3-KT: 65.4;HMC-1: 152.1;MOLT-4: 162.4;NB-4: 59.8;REH: 119.3;THP-1: 62.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA043113: AB_10967343" "prognostic favorable (7.57e-5)" "unprognostic (6.06e-2)" "unprognostic (3.43e-1)" "prognostic favorable (2.01e-4)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (1.14e-2)" "unprognostic (5.38e-3)" "unprognostic (1.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (4.26e-6)" "unprognostic (1.04e-1)" "unprognostic (2.16e-3)" "unprognostic (2.36e-1)" "unprognostic (2.07e-1)" 6.8 3.1 4.0 12.4 3.8 75.6 4.6 4.0 7.3 13.3 4.7 2.5 1.7 1.3 0.4 108.8 2.4 4.6 1.9 4.1 4.1 2.0 1.4 13.1 4.2 5.4 4.5 0.8 1.2 0.4 1.4 7.6 5.1 11.6 1.8 0.1 19.5 2.5 0.6 50.8 2.5 3.1 4.9 8.8 4.3 1.4 6.6 32.0 1.2 0.9 12.1 28.1 41.6 6.4 44.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 18.7 0.1 0.1 0.0 0.1 36.2 0.0 65.4 0.0 0.1 0.0 19.1 0.1 0.0 0.0 27.2 152.1 0.0 40.0 0.2 26.2 0.0 0.0 16.6 0.1 0.3 0.0 0.0 162.4 59.8 0.1 2.9 0.0 119.3 0.0 0.2 0.0 23.6 0.2 0.0 4.6 0.2 0.2 0.0 0.0 62.1 0.1 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.3 29.8 0.1 19.4 29.1 14.3 0.0 21.8 1.1 0.0 2.0 0.3 28.8 0.0 0.0 0.0 6.9 4.4 15.5 67.1 8.7 13.3 4.0 3.8 4.0 7.3 4.1 4.1 5.4 4.5 5.1 4.9 6.6 6.4 1.0 9.6 8.8 0.0 2.2 67.2 141.5 65.5 9.1 0.2 7.4 3.7 0.5 0.0 39.0 3.7 0.0 0.5 27.6 0.5 0.0 0.7 0.5 1.4 0.5 3.1 6.6 21.0 1.3 0.0 0.8 2.5 3.6 3.9 34.3 0.0 0.7 0.0 66.5 0.0 0.4 2.2 57.0 36.2 190.6 0.8 0.0 78.3 21.4 7.5 32.0 0.0 0.0 0.0 0.2 13.2 0.3 0.0 3.6 69.3 0.0 0.1 21.7 0.1 19.7 0.3 3.3 4.0 2.0 38.0 95.8 0.4 19.6 0.1 1.4 173.8 GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" 6.8 4.2 4.6 5.9 5.0 5.0 5.1 8.8 6.2 13.4 2.8 4.1 4.8 4.3 4.1 44.9 3.8 3.5 8.2 4.8 6.1 6.2 4.7 9.3 7.2 6.3 5.5 5.4 3.7 6.5 3.0 7.5 6.6 3.9 3.9 5.6 7.2 4.0 8.8 4.5 5.0 3.6 5.3 4.8 5.5 4.6 6.0 5.3 6.5 5.1 11.0 4.9 11.0 5.9 16.3 9.5 12.5 44.2 7.9 8.1 25.2 14.8 11.9 13.5 19.1 22.7 10.6 17.5 15.0 7.6 18.0 12.4 20.3 20.8 18.8 9.0 18.0 21.1 16.0 11.9 22.1 21.2 11.1 12.4 24.5 16.3 26.8 5.9 9.7 22.1 18.5 39.4 9.9 11.2 13.4 17.1 16.0 9.9 34.5 17.3 17.0 22.0 8.8 15.7 25.3 20.7 14.7 25.9 44.5 9.3 23.0 24.5 11.2 14.6 16.3 10.4 21.3 14.7 21.6 16.6 14.3 28.9 14.5 9.9 2.5 3.6 5.1 2.4 6.1 3.9 7.6 5.6 3.9 1.8 9.9 7.5 2.0 3.8 2.8 1.1 15.1 4.8 4.6 5.0 8.8 6.2 4.8 6.1 6.3 5.5 6.6 5.3 6.0 5.9 20.9 9.6 6.4 2.3 3.3 17.8 5.3 9.9 9.6 6.1 7.0 6.0 8.8 4.3 9.3 9.2 8.4 9.2 3.5 5.1 1.9 5.3 11.6 2.3 4.9 36.0 6.0 11.4 4.3 6.0 18.2 6.0 3.6 5.6 2.5 6.6 20.3 7.1 6.0 3.3 5.1 4.5 10.2 9.7 7.4 5.4 4.1 2.7 7.2 5.6 4.5 5.4 2.1 3.0 4.9 7.5 3.1 5.3 4.4 7.1 6.5 6.2 5.0 6.7 0.0 6.1 6.0 22.6 12.0 10.0 19.6 5.6 9.2 5.2 7.2 8.2 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2087.9" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 4033.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 4998.3;OE19: 7810.3" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 290.5 276.2 346.8 232.1 370.3 601.3 288.7 358.9 425.7 641.9 695.8 329.6 394.6 331.9 280.3 2087.9 647.5 435.8 367.2 341.4 381.9 567.7 45.1 468.3 321.8 375.7 379.2 306.9 340.9 737.4 320.2 326.9 378.5 291.7 197.1 137.9 541.2 780.4 355.0 731.4 321.7 214.2 367.0 257.2 535.5 45.8 378.1 296.9 579.0 312.5 380.8 526.5 946.2 377.7 1202.5 1599.4 763.7 1198.9 577.8 645.2 705.3 511.3 678.1 761.2 589.3 2956.3 1225.0 3.3 1144.7 813.5 683.7 1707.8 2073.9 2248.5 214.4 848.0 765.3 59.9 1107.6 0.5 852.2 400.3 667.6 807.2 4998.3 609.9 583.3 560.9 1160.2 847.2 1318.2 321.8 605.7 4.3 918.2 1100.6 1475.2 7810.3 681.3 844.8 129.6 3.8 1236.8 3.6 260.6 754.3 719.1 230.9 2394.0 598.2 3.6 656.3 634.5 351.6 883.8 740.6 378.6 200.0 1353.9 447.1 400.0 652.4 747.8 56.0 3145.4 246.6 720.0 2470.8 271.9 509.2 322.4 597.7 3582.7 476.3 267.8 466.5 130.5 1443.8 1608.5 1435.1 363.3 3948.4 346.8 370.3 358.9 425.7 341.4 381.9 375.7 379.2 378.5 367.0 378.1 377.7 466.7 1153.8 872.3 25.5 296.8 865.6 1914.8 3813.8 767.2 170.0 628.7 838.3 297.3 987.9 2763.5 1230.4 33.3 2116.8 372.4 655.0 1805.9 1811.9 4.9 1381.0 589.0 431.4 368.2 166.3 6.8 1444.4 1703.9 710.5 781.9 1020.9 269.9 795.0 382.3 10.5 861.2 70.7 10.1 992.4 1930.7 597.9 1090.3 25.5 572.3 703.5 1531.5 27.2 2166.5 558.5 459.3 17.6 38.4 1412.1 948.9 400.2 591.6 2266.2 844.4 3495.5 3715.4 274.4 361.6 401.3 941.7 4.8 54.9 4033.7 1061.7 1645.5 342.5 527.8 1118.5 3418.6 HEPHL1 DKFZp686F22190 ENSG00000181333 "Hephaestin like 1" Q6MZM0 11 94021354-94114208 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 4.5;lymphoid tissue: 9.5;skin 1: 3.8;vagina: 4.5" "Cell type enriched" "Detected in some" 5 "Basal keratinocytes: 10.5" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.4;HBEC3-KT: 2.6" "Region enriched" "Detected in single" 12 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA031517 Uncertain NA NA 260000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA031517: AB_10603769" "unprognostic (9.16e-2)" "prognostic unfavorable (4.94e-4)" "unprognostic (2.40e-1)" "unprognostic (3.26e-6)" "unprognostic (3.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-2)" "unprognostic (6.71e-2)" "unprognostic (5.34e-1)" "unprognostic (1.09e-1)" "unprognostic (7.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 9.5 0.0 4.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 10.5 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.1 0.0 0.4 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 HERC6 FLJ20637 ENSG00000138642 "HECT and RLD domain containing E3 ubiquitin protein ligase family member 6" Q8IVU3 4 88378739-88443097 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 116.1;BJ hTERT+ SV40 Large T+ RasG12V: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035846 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "HPA035846: AB_10673487" "unprognostic (1.95e-2)" "unprognostic (2.71e-1)" "unprognostic (2.23e-2)" "unprognostic (2.67e-2)" "unprognostic (8.61e-2)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (5.95e-2)" "unprognostic (1.52e-2)" "unprognostic (6.22e-2)" "prognostic favorable (7.14e-5)" "unprognostic (1.80e-1)" "unprognostic (2.59e-1)" "unprognostic (8.43e-3)" "unprognostic (3.77e-2)" 4.1 5.5 6.5 5.4 7.2 7.9 6.2 5.2 8.8 14.2 4.3 6.1 5.3 8.5 4.2 20.9 9.7 10.7 9.6 7.0 7.6 6.0 4.8 8.1 5.0 8.2 6.6 8.3 5.4 7.1 4.4 5.5 7.3 8.4 6.1 4.4 30.5 5.1 3.0 4.1 5.3 8.0 11.7 8.2 7.2 3.9 6.9 12.3 4.3 4.7 5.3 6.0 11.2 6.8 6.7 4.5 0.3 0.9 0.3 3.8 1.2 0.8 22.1 116.1 85.8 0.4 8.3 0.0 1.5 2.1 18.8 2.5 10.9 5.7 7.6 13.9 2.2 6.3 3.8 0.6 3.7 11.3 4.2 5.2 1.3 9.1 0.3 7.0 3.4 5.2 0.0 1.5 2.6 4.1 5.3 3.6 1.5 6.0 2.2 3.6 0.1 0.5 7.8 8.2 0.3 2.7 8.2 2.7 13.5 5.6 4.8 2.0 1.2 1.6 2.1 0.2 2.1 0.3 0.1 0.0 5.2 2.5 5.4 4.4 3.2 4.7 6.4 3.4 12.8 3.5 8.9 6.3 2.8 3.0 6.9 4.7 1.9 6.0 7.4 0.3 12.5 4.2 6.5 7.2 5.2 8.8 7.0 7.6 8.2 6.6 7.3 11.7 6.9 6.8 11.4 12.8 10.6 14.4 5.8 2.8 5.2 3.3 4.6 18.1 4.9 4.6 13.9 7.2 9.8 5.5 16.7 5.8 5.0 8.3 0.0 7.8 1.3 6.4 3.9 11.5 1.8 4.8 21.5 17.4 1.8 6.6 5.6 5.0 5.7 25.9 5.3 2.2 5.0 1.7 25.8 2.9 4.1 2.2 0.8 1.6 4.4 4.7 5.4 28.1 5.7 3.7 4.1 24.1 2.8 13.3 2.4 5.7 3.8 8.3 6.2 4.1 14.6 1.0 6.6 2.0 3.6 0.8 2.1 18.4 1.1 2.5 8.2 13.3 2.5 8.0 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 113.0;salivary gland: 34.5;vagina: 31.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Basal respiratory cells: 12.5;Prostatic glandular cells: 4.4;Squamous epithelial cells: 2.1;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 6.9;RT4: 25.6;SK-BR-3: 8.6" HPA014001 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA014001: AB_2668919" "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 113.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 34.5 0.0 0.0 3.5 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.8 0.0 0.0 4.8 0.4 31.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 6.9 0.0 1.9 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 12.5 0.0 0.0 0.5 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 0.3 2.1 3.4 0.0 0.0 0.0 0.0 0.2 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 47.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.4 3.7 2.6 16.7 4.6 8.7 3.1 2.0 3.2 4.1 1.9 7.8 7.4 1.7 3.9 14.6 2.8 5.1 1.4 2.7 3.3 3.4 1.6 4.1 24.3 4.1 3.6 1.2 3.4 1.0 1.9 2.6 3.9 3.6 7.7 0.1 6.9 2.1 0.5 15.0 8.0 2.5 2.7 14.2 7.2 0.7 4.4 16.5 4.5 0.3 20.4 8.4 6.8 4.6 17.8 13.9 3.7 0.4 6.7 9.2 3.9 7.1 22.3 9.4 10.4 11.5 26.9 35.3 18.6 14.5 11.5 23.0 0.1 18.1 2.2 5.5 3.5 4.7 8.8 7.6 8.4 29.5 14.8 12.2 3.2 7.7 1.7 10.9 14.2 9.4 2.3 10.0 10.5 3.6 19.2 47.7 5.2 4.3 10.9 9.7 4.3 27.7 10.7 29.4 0.0 0.0 2.9 22.9 4.2 4.5 13.8 20.3 26.5 9.0 5.5 6.9 8.5 3.5 1.8 23.3 17.1 24.2 3.7 12.2 32.8 0.6 21.2 23.3 14.8 26.4 32.4 30.1 9.5 14.0 25.7 27.3 2.2 23.9 13.4 3.2 52.8 28.6 2.6 4.6 2.0 3.2 2.7 3.3 4.1 3.6 3.9 2.7 4.4 4.6 0.4 0.0 4.5 0.7 13.7 1.9 3.6 37.8 1.8 0.0 4.3 3.7 0.9 4.3 16.3 0.0 0.0 4.2 7.9 11.7 0.0 12.1 3.3 1.5 0.9 0.7 3.6 4.4 1.5 12.6 5.2 3.4 17.3 2.4 5.1 3.7 2.2 0.8 13.8 0.0 1.5 6.4 8.2 12.9 0.7 7.0 0.9 16.0 7.2 1.9 9.0 0.0 14.4 1.0 0.2 15.9 21.5 0.7 6.4 3.2 10.7 3.5 14.5 0.0 0.0 0.7 3.1 0.3 0.9 11.1 4.8 1.5 15.8 3.9 10.2 11.6 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "esophagus: 411.3;lymphoid tissue: 115.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 1.2;U-266/70: 1.2" "Not detected" "Not detected" "Secreted to blood" NA NA 327000 "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.37e-1)" "unprognostic (9.66e-3)" "unprognostic (5.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 411.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 115.4 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IQANK1 ENSG00000203499 "IQ motif and ankyrin repeat containing 1" A8MXQ7 8 143734139-143790645 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 41.2;skin 1: 28.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.4;Breast myoepithelial cells: 6.3;Collecting duct cells: 7.3;Cytotrophoblasts: 8.8;Endometrial ciliated cells: 23.2;Extravillous trophoblasts: 6.0;Respiratory ciliated cells: 12.4;Syncytiotrophoblasts: 10.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.5;HaCaT: 29.4;hTCEpi: 35.4;MCF7: 72.3;OE19: 68.6;RT4: 30.3;SK-BR-3: 30.0;T-47d: 64.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.45e-3)" "unprognostic (3.38e-1)" "unprognostic (7.46e-2)" "unprognostic (4.94e-3)" "unprognostic (4.31e-3)" "unprognostic (1.98e-1)" "unprognostic (5.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (4.49e-3)" "unprognostic (1.42e-2)" "unprognostic (1.47e-1)" "unprognostic (1.79e-1)" "unprognostic (9.40e-2)" 0.2 0.3 0.8 0.6 1.2 0.8 6.1 1.2 1.0 8.3 2.2 1.8 1.3 0.8 21.5 41.2 13.6 1.3 0.2 1.1 0.4 3.0 0.5 3.5 0.2 1.5 2.9 0.2 4.7 3.3 1.9 3.5 1.0 7.2 2.4 1.9 8.0 2.0 0.3 28.7 0.9 0.2 0.7 0.3 4.1 8.4 0.6 0.6 2.6 0.0 3.9 6.3 18.5 1.0 17.6 1.1 0.2 0.8 0.1 0.2 19.5 0.3 0.0 0.1 0.2 9.2 26.5 0.1 2.0 0.1 0.1 29.4 0.9 3.4 0.2 0.2 0.8 0.1 2.8 2.1 0.5 0.2 0.2 0.3 35.4 0.2 0.7 0.4 0.0 0.6 1.3 0.2 0.0 72.3 0.1 0.2 1.5 68.6 1.1 0.2 0.1 0.6 1.9 30.3 9.8 0.2 2.6 30.0 1.1 2.3 64.4 0.4 0.2 0.3 1.0 0.5 0.1 0.5 0.2 0.2 0.1 0.3 0.5 0.8 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.1 1.4 0.2 0.2 0.2 0.0 0.0 0.8 1.2 1.2 1.0 1.1 0.4 1.5 2.9 1.0 0.7 0.6 1.0 0.1 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.4 6.3 0.0 0.0 3.7 7.3 0.0 8.8 0.0 0.0 0.0 2.0 0.0 23.2 0.7 0.3 0.0 0.0 0.0 1.6 6.0 0.4 0.0 5.2 1.3 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 1.3 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 0.2 0.0 0.0 JMJD7 ENSG00000243789 "Jumonji domain containing 7" P0C870 15 41828092-41837581 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 5.2;Basal squamous epithelial cells: 1.8;Gastric mucus-secreting cells: 2.0;Squamous epithelial cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 31.2;RT4: 43.5" "Low region specificity" "Detected in all" HPA005726 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA005726: AB_1852017" "unprognostic (2.92e-1)" "unprognostic (7.99e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.77e-1)" "unprognostic (2.42e-1)" "unprognostic (8.74e-3)" "unprognostic (3.13e-1)" "unprognostic (7.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" 6.7 8.4 6.3 4.2 6.2 8.2 9.0 19.9 9.5 13.6 8.0 7.3 4.8 6.5 3.1 35.4 8.6 6.5 11.2 5.8 6.3 10.1 10.3 10.8 7.3 5.8 5.2 11.6 15.9 9.0 9.8 3.0 7.0 14.5 3.0 1.9 21.9 6.8 7.7 33.3 8.0 2.9 5.1 7.9 11.5 6.7 5.9 5.6 15.6 6.6 6.6 11.4 21.0 7.0 7.9 7.5 9.3 2.6 2.5 1.7 5.8 3.1 6.6 5.1 4.1 10.5 5.9 1.0 6.4 2.0 5.3 19.6 4.3 15.6 1.6 7.7 4.6 10.5 10.4 6.5 4.1 5.1 11.0 1.1 13.6 3.4 7.2 4.7 5.8 9.9 7.0 6.2 3.7 10.8 6.6 4.9 4.0 31.2 4.8 2.9 6.3 7.6 11.5 43.5 9.9 3.5 2.6 13.5 4.3 2.7 26.2 5.4 5.4 3.7 8.3 8.0 6.1 10.2 3.7 3.2 4.9 12.4 5.7 6.1 14.8 10.8 14.1 15.8 14.8 7.2 15.7 18.6 10.6 11.1 19.7 15.6 3.9 13.0 15.8 6.7 16.7 12.6 6.3 6.2 19.9 9.5 5.8 6.3 5.8 5.2 7.0 5.1 5.9 7.0 0.1 3.2 5.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.2 2.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 3.4 0.1 0.0 0.6 0.0 0.0 0.0 KCTD5 FLJ20040 ENSG00000167977 "Potassium channel tetramerization domain containing 5" Q9NXV2 16 2682523-2709030 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 62.6" "Group enriched" "Detected in all" 5 "dendritic cells: 62.6;granulocytes: 16.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.48e-2)" "unprognostic (1.87e-1)" "unprognostic (6.72e-2)" "unprognostic (5.15e-3)" "unprognostic (1.60e-1)" "unprognostic (9.95e-3)" "unprognostic (1.47e-3)" "unprognostic (1.45e-3)" "unprognostic (3.74e-1)" "unprognostic (1.52e-1)" "unprognostic (2.43e-3)" "unprognostic (8.21e-2)" "unprognostic (4.06e-3)" "unprognostic (2.15e-2)" "unprognostic (5.52e-3)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" 11.8 12.0 14.0 15.4 14.9 14.8 10.4 14.5 15.8 14.5 11.2 23.3 16.8 10.7 6.5 34.4 9.8 11.0 11.3 13.4 13.5 10.3 17.8 12.0 21.1 15.8 14.8 9.8 9.8 8.2 10.8 11.8 15.0 10.6 15.5 6.4 15.1 6.7 16.1 19.0 17.6 8.3 15.6 18.1 16.5 13.0 15.2 15.7 8.8 10.5 16.6 14.9 16.8 16.0 46.9 27.2 23.0 33.6 17.0 20.1 25.9 37.3 21.2 48.1 37.6 32.2 61.9 39.4 26.8 36.3 27.7 40.2 32.5 37.3 24.4 32.0 27.2 41.1 16.0 40.7 33.1 41.1 53.9 21.5 37.6 43.1 38.2 24.6 22.4 40.1 41.2 44.3 29.5 54.6 49.5 41.2 36.2 30.5 48.4 64.7 30.3 73.8 24.2 15.8 38.3 35.2 47.6 48.3 43.8 14.7 40.6 40.1 27.1 60.2 33.0 38.0 44.6 39.9 27.5 58.7 24.3 36.9 47.5 1.1 7.2 16.5 5.1 7.0 4.6 5.4 4.4 6.0 11.5 7.4 4.3 4.8 3.8 6.3 7.0 62.6 4.3 4.3 14.0 14.9 14.5 15.8 13.4 13.5 15.8 14.8 15.0 15.6 15.2 16.0 13.3 9.6 5.9 2.9 19.5 26.9 13.3 7.3 12.5 10.3 14.8 14.4 8.6 5.7 5.6 3.7 2.1 21.5 55.6 46.3 7.9 17.8 1.2 10.0 11.7 10.1 9.0 16.6 5.2 11.8 27.2 9.7 31.6 17.4 4.5 6.4 4.6 8.3 21.1 18.5 4.7 22.3 8.2 27.7 15.4 2.8 7.5 24.0 17.8 8.4 22.1 16.3 12.3 9.0 9.7 30.5 29.6 8.2 13.0 11.3 18.3 7.7 5.6 8.5 13.1 11.0 12.9 5.8 16.6 17.9 31.3 39.4 17.0 9.4 22.7 18.4 KDM2B "CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2" ENSG00000089094 "Lysine demethylase 2B" Q8NHM5 12 121429096-121581023 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071257 Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA071257: " "unprognostic (7.67e-2)" "unprognostic (3.72e-3)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.74e-6)" "unprognostic (1.16e-1)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-1)" "prognostic favorable (8.64e-4)" "unprognostic (1.77e-1)" "unprognostic (4.44e-3)" "unprognostic (1.44e-2)" "unprognostic (3.90e-2)" "unprognostic (7.07e-2)" "unprognostic (4.82e-2)" 9.7 8.4 7.1 18.9 8.7 16.9 10.0 12.9 10.7 15.6 7.4 12.2 8.2 11.5 5.5 20.2 12.4 7.0 8.7 7.3 5.6 11.1 15.6 13.1 22.9 8.3 6.3 15.2 11.6 10.8 9.4 7.3 9.2 9.5 7.6 9.7 12.6 6.1 15.2 28.0 18.9 8.3 5.4 21.4 10.9 14.0 7.8 23.1 11.2 6.1 21.6 12.3 16.9 9.0 15.2 19.1 31.3 9.8 8.7 7.6 34.8 12.4 19.1 17.8 14.9 24.0 7.7 69.3 20.6 11.2 9.9 13.1 34.3 13.7 14.4 29.3 24.0 38.0 15.9 19.4 10.3 44.0 29.5 6.9 7.4 16.9 12.3 19.1 12.7 33.6 31.4 8.8 8.5 20.4 54.5 51.8 55.8 11.0 15.1 61.0 16.4 34.1 9.8 24.5 37.1 21.4 23.8 14.0 14.4 29.5 25.0 49.2 17.3 19.0 15.4 19.2 13.9 23.9 21.3 64.5 17.6 35.2 12.3 4.5 2.8 2.4 6.3 2.3 4.9 9.5 4.9 3.5 3.9 9.3 4.3 5.8 0.4 2.0 1.7 3.5 4.6 3.4 7.1 8.7 12.9 10.7 7.3 5.6 8.3 6.3 9.2 5.4 7.8 9.0 6.8 0.0 10.6 28.1 36.8 17.0 7.1 4.0 13.6 20.1 10.3 6.7 14.6 14.3 5.4 11.0 12.5 6.7 43.3 3.8 11.7 7.5 57.0 13.0 7.0 8.8 5.4 22.5 36.2 5.8 11.2 8.3 9.2 12.0 14.0 16.5 9.7 15.4 24.4 15.2 41.6 6.1 6.1 21.1 61.0 60.1 7.8 25.5 16.0 26.2 48.0 4.1 24.7 31.2 44.1 5.8 4.7 7.2 34.1 11.2 6.5 4.2 5.7 16.1 19.7 6.5 8.1 11.4 18.3 13.9 15.2 6.6 24.8 6.2 7.4 6.3 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Basal respiratory cells: 61.4;Club cells: 113.9;Pancreatic endocrine cells: 74.8;Prostatic glandular cells: 68.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 67.2;HaCaT: 158.7;OE19: 68.1" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 8.6 0.6 0.7 0.2 0.4 0.6 6.2 1.2 0.4 111.8 1.0 1.5 0.3 1.7 0.2 412.5 8.6 3.5 1.3 0.3 1.4 0.6 0.3 8.7 0.0 2.6 1.7 19.7 0.6 0.2 1.5 0.2 2.8 7.2 0.6 0.3 55.2 0.5 0.2 65.7 2.6 0.6 0.7 0.2 1.8 6.0 1.0 0.3 0.6 0.1 18.8 0.6 190.6 0.4 21.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 67.2 0.0 6.6 0.0 0.1 158.7 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 68.1 0.6 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.4 0.3 1.4 2.6 1.7 2.8 0.7 1.0 0.4 0.3 32.1 2.6 0.0 0.0 7.5 15.6 61.4 9.1 1.0 12.3 14.0 0.7 8.6 113.9 0.0 0.0 0.0 0.2 1.2 0.0 7.5 0.3 2.1 1.0 1.7 0.0 0.0 0.1 15.4 0.0 6.0 1.1 8.0 0.0 0.1 1.1 0.0 0.1 0.0 0.6 0.0 22.4 0.0 0.6 0.6 11.5 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.5 74.8 0.0 6.0 0.0 68.6 0.0 0.0 15.8 0.5 0.0 0.4 2.6 1.0 1.6 28.0 4.3 0.0 0.5 0.5 0.0 29.6 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Enteroendocrine cells: 40.3;Intestinal goblet cells: 24.9;Ionocytes: 14.2;Late spermatids: 34.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 108.5 2.2 2.1 4.0 0.0 0.0 208.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.1 0.5 0.8 0.0 64.7 0.0 0.0 0.6 5.8 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.1 0.0 8.9 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.5 0.5 0.2 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 30.7 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 14.2 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.2 8.4 0.0 0.0 0.0 0.0 1.3 1.7 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 519.9" "Group enriched" "Detected in some" 4 "Late spermatids: 246.9;Squamous epithelial cells: 68.3" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.2 0.2 0.1 0.2 0.1 0.0 1.6 0.1 0.2 96.3 0.9 0.6 1.6 0.5 0.4 519.9 0.5 1.1 0.2 0.1 0.1 0.1 0.2 0.7 0.0 0.2 0.5 0.2 4.4 0.4 0.3 0.0 0.1 0.6 0.1 0.0 74.9 0.0 0.1 10.8 0.8 0.3 0.1 0.1 1.4 4.3 0.1 0.2 0.3 0.0 63.5 0.2 122.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 27.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.6 1.1 4.0 0.0 0.9 1.9 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.1 0.1 0.3 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 246.9 0.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.7 68.3 1.3 0.0 0.4 0.4 0.0 2.1 KLRG2 "CLEC15B, FLJ44186" ENSG00000188883 "Killer cell lectin like receptor G2" A4D1S0 7 139452690-139483673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0;salivary gland: 4.3;thyroid gland: 4.1" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 5.2;Collecting duct cells: 7.3;Squamous epithelial cells: 14.2;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 11 "testis cancer: 42.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.7;HAP1: 15.7;NTERA-2: 8.2;SCLC-21H: 7.4;SK-BR-3: 31.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018199 Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA018199: AB_2133260" "unprognostic (2.50e-2)" "unprognostic (3.05e-2)" "unprognostic (9.82e-2)" "unprognostic (5.38e-8)" "unprognostic (2.41e-1)" "unprognostic (1.97e-2)" "unprognostic (3.13e-2)" "prognostic favorable (8.61e-4)" "unprognostic (2.14e-2)" "unprognostic (2.92e-1)" "unprognostic (5.19e-2)" "unprognostic (8.83e-2)" "unprognostic (1.10e-3)" "unprognostic (5.66e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-2)" "unprognostic (2.34e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.0 0.4 2.5 0.0 2.9 0.0 0.1 0.0 0.0 0.1 2.8 0.3 0.4 0.1 0.1 0.1 0.0 4.3 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.9 4.1 0.1 0.7 0.1 1.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.0 2.0 0.0 0.0 4.3 0.0 0.0 2.2 15.7 0.0 0.0 0.0 3.9 0.0 0.6 0.0 0.1 0.0 0.3 0.0 6.6 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 2.8 2.5 0.0 8.2 0.0 0.1 0.0 0.0 0.0 0.5 0.1 7.4 0.4 2.3 31.9 0.0 6.1 7.1 1.5 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.5 0.8 0.3 5.2 0.0 1.3 1.4 0.5 0.0 0.1 7.3 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 1.6 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 14.2 1.0 7.7 0.0 0.0 0.3 0.5 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.2;esophagus: 1025.8;skin 1: 360.7;vagina: 489.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 906.1;Basal prostatic cells: 596.6;Suprabasal keratinocytes: 1348.4;Urothelial cells: 506.9" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 816.8" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" 7.1 1.4 0.2 0.1 0.3 0.3 17.4 3.9 0.6 307.2 0.0 0.2 0.0 1.0 0.0 1025.8 0.7 2.4 0.5 1.0 0.0 0.8 0.4 0.2 0.1 0.0 0.0 0.3 0.7 0.0 1.4 0.1 0.1 6.3 0.0 0.0 180.6 37.7 0.5 360.7 0.2 0.1 0.0 0.2 0.6 2.6 0.0 16.9 0.3 0.0 112.1 5.5 489.4 0.4 20.0 1.7 0.0 0.0 0.2 0.0 0.2 1.5 0.4 0.5 0.2 0.3 4.9 0.1 2.9 0.1 0.2 24.8 0.0 5.6 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 816.8 0.3 17.6 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.0 0.3 0.0 127.1 0.7 0.0 0.2 98.1 0.8 6.2 0.0 0.0 57.1 1.5 0.0 0.9 0.0 0.0 0.2 0.0 1.6 4.5 0.4 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 3.9 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 906.1 596.6 70.1 16.5 0.0 37.8 27.1 0.1 0.0 94.6 1.8 0.0 0.1 0.6 0.0 0.0 1.0 0.0 2.6 0.6 9.2 0.0 0.0 0.0 5.8 3.2 11.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 94.1 0.0 0.3 1.1 64.0 0.0 0.0 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 127.3 0.0 0.0 17.1 0.0 0.0 0.0 9.3 0.0 0.3 88.1 1348.4 0.1 3.4 0.0 0.0 506.9 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT78 K5B ENSG00000170423 "Keratin 78" Q8N1N4 12 52837804-52849092 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 972.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.4;Glandular and luminal cells: 1.9;Spermatocytes: 2.1;Spermatogonia: 8.0;Squamous epithelial cells: 6.7;Suprabasal keratinocytes: 4.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "EFO-21: 5.5;RT4: 1.6;SK-BR-3: 3.6;U-87 MG: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA039724 Enhanced NA NA 70000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA039724: AB_10795255" "unprognostic (5.36e-2)" "unprognostic (5.89e-2)" "unprognostic (2.95e-2)" "unprognostic (3.25e-2)" "unprognostic (1.88e-1)" "unprognostic (2.18e-2)" "unprognostic (3.01e-3)" "unprognostic (8.88e-16)" "unprognostic (3.50e-2)" "unprognostic (6.92e-1)" "unprognostic (7.55e-2)" "unprognostic (1.25e-1)" 0.4 0.2 0.0 0.0 0.0 0.1 3.4 0.0 0.5 227.1 0.0 0.1 0.0 0.1 0.0 972.7 0.1 0.9 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 141.7 0.0 0.3 126.7 0.2 0.0 0.0 0.1 1.0 1.5 0.3 0.4 0.3 0.0 134.2 0.4 221.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.6 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.5 0.6 0.0 0.8 2.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 8.0 6.7 4.4 0.3 0.0 0.0 0.2 0.5 LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.8;seminal vesicle: 8.0" "Cell type enriched" "Detected in some" 8 "Basal prostatic cells: 8.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 3800000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.50e-3)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-4)" "unprognostic (1.22e-1)" "unprognostic (7.84e-2)" "unprognostic (9.47e-2)" "unprognostic (3.94e-8)" "unprognostic (2.07e-3)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" 0.0 0.0 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.0 0.4 0.0 0.0 0.0 0.0 12.8 1.9 0.0 0.5 1.1 0.4 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.1 0.0 1.9 0.2 0.4 0.0 0.0 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.9 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LEXM "C1orf177, FLJ40201, LEM" ENSG00000162398 "Lymphocyte expansion molecule" Q3ZCV2 1 54806063-54842252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 12.7;testis: 4.8;vagina: 4.0" "Group enriched" "Detected in some" 5 "Early spermatids: 37.7;Late spermatids: 46.0" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035889, HPA035890" Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA035889: AB_2674844, HPA035890: AB_10669535" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (5.01e-2)" "unprognostic (3.69e-2)" "unprognostic (1.50e-2)" "unprognostic (8.32e-2)" "unprognostic (7.28e-2)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (5.13e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (3.64e-1)" "unprognostic (1.81e-1)" 0.0 0.1 0.1 0.0 1.6 0.1 0.1 0.1 0.9 1.5 0.0 0.4 1.6 0.0 0.1 12.7 0.1 0.0 0.0 0.1 0.2 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 1.0 1.3 0.0 0.0 0.1 0.2 4.8 0.1 0.0 0.0 0.0 0.5 0.0 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.2 0.0 0.8 2.0 0.0 0.0 0.1 2.5 0.0 2.0 0.0 0.1 0.2 1.0 0.1 1.6 0.1 0.9 0.1 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 37.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 46.0 0.3 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.1 0.0 0.7 0.3 0.0 4.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.6 0.0 0.0 1.0 0.0 0.6 0.2 LRRC8E FLJ23420 ENSG00000171017 "Leucine rich repeat containing 8 VRAC subunit E" Q6NSJ5 19 7888505-7902021 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9.6;Glandular and luminal cells: 13.0;Squamous epithelial cells: 11.6;Suprabasal keratinocytes: 11.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 36.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020466 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "HPA020466: AB_1853352" "unprognostic (3.79e-2)" "unprognostic (2.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-3)" "unprognostic (8.28e-3)" "unprognostic (7.64e-2)" "unprognostic (1.71e-2)" "unprognostic (3.36e-1)" "unprognostic (8.38e-2)" "unprognostic (3.98e-6)" "unprognostic (1.11e-1)" "unprognostic (2.30e-2)" "unprognostic (3.29e-2)" "unprognostic (3.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-1)" 0.6 4.9 0.4 0.8 0.5 1.9 4.6 1.0 0.6 3.3 0.6 1.0 0.9 1.4 6.2 6.4 2.1 2.3 0.9 0.5 0.1 1.9 4.1 4.3 0.7 0.4 0.2 0.3 7.2 3.3 0.5 1.3 0.7 3.5 1.1 0.4 7.7 2.1 0.5 10.6 0.5 0.4 0.0 0.3 3.6 0.7 0.3 0.1 2.0 0.4 2.8 2.9 4.7 1.4 23.5 6.0 0.2 0.6 1.1 5.6 3.5 10.1 8.7 15.8 12.3 7.7 5.3 0.6 7.5 9.8 22.5 18.3 7.7 9.8 14.9 0.4 8.5 0.3 3.1 8.2 4.1 0.3 0.5 9.1 13.9 10.5 7.8 21.2 2.0 4.1 6.5 0.8 1.9 11.9 0.1 0.5 1.7 4.3 21.9 1.4 0.2 0.6 12.0 21.3 0.5 0.4 7.6 9.6 0.3 1.7 12.8 0.5 2.6 4.8 8.7 13.2 5.8 1.5 2.9 0.3 36.4 0.8 1.7 1.7 0.4 0.5 0.5 0.3 0.6 0.6 0.4 0.4 0.1 0.8 0.5 0.6 1.5 1.1 0.4 0.5 0.4 0.2 0.4 0.5 1.0 0.6 0.5 0.1 0.4 0.2 0.7 0.0 0.3 1.4 0.1 3.2 5.5 0.0 0.1 9.6 5.0 1.5 6.2 0.0 8.2 5.7 0.2 1.5 5.4 1.8 0.0 0.7 0.0 1.1 0.0 6.2 0.0 7.7 2.4 0.5 0.0 0.0 0.1 6.0 1.0 1.0 3.6 13.0 1.3 0.4 0.0 3.2 0.1 0.0 0.1 1.2 4.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.0 5.0 0.1 0.5 6.5 0.0 0.0 0.8 0.9 0.0 0.3 11.6 11.2 1.9 0.5 0.1 1.3 5.9 LYPD2 "LYPDC2, RGTR430, UNQ430" ENSG00000197353 "LY6/PLAUR domain containing 2" Q6UXB3 8 142750150-142752532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 347.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 97.0;Club cells: 378.7;Ionocytes: 71.2;Respiratory ciliated cells: 77.4" "Cancer enhanced" "Detected in many" "cervical cancer: 45.9;ovarian cancer: 46.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "non-classical monocyte: 440.1" "Lineage enriched" "Detected in many" 22 "monocytes: 440.1" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HaCaT: 2.8;OE19: 1.9" "Low region specificity" "Detected in many" HPA028599 Uncertain "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA028599: AB_10603777" "prognostic favorable (2.00e-4)" "unprognostic (3.10e-2)" "prognostic favorable (2.63e-4)" "unprognostic (3.85e-3)" "unprognostic (3.75e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-2)" "unprognostic (3.11e-3)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.12e-1)" "unprognostic (2.04e-1)" 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.4 15.0 0.0 0.0 0.0 0.0 0.0 347.8 0.3 0.2 2.9 0.0 0.0 0.1 1.3 1.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.0 27.0 0.0 0.1 28.8 0.1 0.0 0.0 0.2 23.2 0.0 0.1 2.5 0.0 0.0 26.3 0.0 48.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 33.7 0.4 2.0 0.1 0.2 20.1 0.0 0.2 0.1 0.0 0.0 440.1 1.6 0.1 10.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 97.0 0.0 0.0 0.1 0.0 0.0 0.0 378.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 5.7 0.4 0.4 0.0 0.0 0.0 71.2 1.3 0.0 0.1 0.0 25.3 0.0 0.0 11.2 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 77.4 0.0 0.0 0.0 22.3 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.2 MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 262.6;vagina: 80.4" "Cell type enriched" "Detected in single" 7 "Cytotrophoblasts: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 45.9;HaCaT: 34.3;SK-BR-3: 117.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.86e-3)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (6.46e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" 0.2 0.1 0.3 1.0 0.5 0.0 1.8 0.5 1.3 36.0 0.0 2.9 11.5 0.2 0.1 262.6 0.9 0.5 0.1 0.8 0.0 13.3 13.0 10.0 0.3 0.3 0.0 0.1 1.2 0.0 0.2 0.8 0.5 1.5 2.5 0.3 29.2 0.2 0.3 60.8 4.9 0.1 0.0 0.2 5.8 0.2 0.2 1.1 0.1 0.0 23.5 2.0 80.4 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 45.9 2.7 0.3 0.3 0.0 0.0 34.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 5.7 0.1 0.1 0.2 7.3 0.0 0.1 0.0 11.4 0.3 5.9 2.3 0.0 0.0 117.0 0.0 0.2 0.9 0.7 0.0 0.0 1.2 0.1 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.3 0.8 0.0 0.3 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 373.3;Distal tubular cells: 236.7;Muller glia cells: 91.5;Oligodendrocytes: 168.1;Skeletal myocytes: 82.3;Squamous epithelial cells: 90.9" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cell line enhanced" "Detected in some" "HDLM-2: 516.4;MOLT-4: 722.0;RPMI-8226: 256.7;RPTEC TERT1: 2531.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" 5.3 1.8 251.3 10.8 333.9 12.7 4.4 264.8 400.2 450.7 177.4 50.8 2.2 2.6 8.3 2817.9 8.9 2.9 17.9 260.8 256.7 400.4 1.7 25.3 25.1 281.3 282.1 3.2 3.0 0.4 3.9 3.4 272.9 21.8 6.3 10.1 544.0 11.1 2.8 12.6 17.0 2.4 264.0 9.4 52.7 1.1 303.2 261.2 21.3 4.3 352.8 15.0 863.2 449.3 51.3 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 12.0 0.0 0.3 2.4 0.2 0.0 0.5 516.4 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.4 0.1 0.1 0.0 722.0 0.2 0.2 0.0 0.0 0.7 0.0 256.7 2531.4 65.3 0.6 0.0 0.1 9.4 1.6 2.1 0.3 0.9 0.8 0.0 0.2 0.1 0.5 0.4 0.3 0.3 0.3 0.4 0.1 0.7 0.6 0.1 4.7 0.3 2.1 3.1 217.6 38.4 0.5 3.5 293.3 138.1 2.6 7.7 0.6 1.2 233.6 71.0 251.3 333.9 264.8 400.2 260.8 256.7 281.3 282.1 272.9 264.0 303.2 449.3 0.9 0.0 0.0 12.1 3.1 1.1 0.2 0.0 1.8 1.5 1.2 0.9 11.3 0.0 1.3 373.3 4.2 0.2 0.9 0.0 236.7 0.1 5.3 4.3 0.6 0.5 0.0 46.1 0.5 0.0 0.0 4.7 24.5 8.2 1.3 3.2 2.5 0.0 0.1 5.0 0.5 0.0 14.2 0.0 1.3 19.5 0.9 1.0 17.8 1.9 2.5 91.5 4.1 6.6 168.1 0.1 0.0 0.0 8.9 0.2 0.0 3.2 0.0 2.7 6.6 82.3 5.3 0.0 0.6 90.9 1.0 0.3 35.8 0.0 0.1 0.8 MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 389.9;Distal enterocytes: 433.3;Pancreatic endocrine cells: 329.8;Suprabasal keratinocytes: 455.8;Urothelial cells: 594.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1042.5;HaCaT: 451.8;OE19: 1132.4;RPTEC TERT1: 385.4;SK-BR-3: 1439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" 14.1 1.8 8.5 10.6 13.4 0.0 65.6 15.3 28.0 41.9 0.0 102.9 64.3 6.7 14.2 259.2 54.4 33.1 2.1 22.2 17.0 85.7 47.0 81.6 1.3 0.0 4.2 0.5 37.4 43.5 35.8 12.0 0.0 26.9 94.2 2.6 62.6 41.2 0.4 121.0 53.0 2.6 0.0 0.4 137.6 12.5 8.3 4.3 147.5 0.1 56.0 69.0 102.6 3.4 1042.5 0.0 1.0 0.3 0.2 0.0 92.9 0.1 2.3 1.2 1.6 87.7 329.0 0.3 56.2 0.0 0.4 451.8 0.8 32.9 0.5 0.9 2.6 0.0 13.8 86.1 0.3 0.6 0.3 0.0 225.5 0.0 34.3 1.7 0.3 0.0 0.2 0.5 0.0 244.9 0.8 0.3 8.2 1132.4 309.2 0.6 0.0 0.7 385.4 257.4 56.7 0.3 17.8 1439.4 2.7 6.8 191.4 3.0 0.0 0.6 3.1 1.3 1.9 5.5 0.8 1.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 13.4 15.3 28.0 22.2 17.0 0.0 4.2 0.0 0.0 8.3 3.4 0.5 112.2 130.8 4.2 2.7 114.7 79.9 59.3 19.9 1.5 118.9 50.7 1.6 90.1 119.7 389.9 0.0 25.0 0.4 433.3 109.5 206.0 0.5 71.8 10.3 3.7 41.9 0.0 62.4 178.6 23.5 4.7 149.9 139.4 14.7 0.0 3.6 44.9 2.9 5.0 9.8 145.9 71.2 0.3 14.3 2.2 0.6 2.3 16.0 3.7 3.6 1.0 0.0 3.5 3.6 329.8 252.9 0.0 1.2 285.4 70.2 19.9 107.5 1.0 0.0 0.0 7.0 1.9 9.7 268.8 455.8 9.3 2.8 0.0 122.5 594.5 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MBD2 ENSG00000134046 "Methyl-CpG binding domain protein 2" Q9UBB5 18 54151606-54224669 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037282, HPA067582, HPA067615" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB037282: AB_477234, HPA067582: AB_2685866, HPA067615: AB_2685872" "unprognostic (4.86e-2)" "unprognostic (7.21e-2)" "prognostic favorable (6.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "unprognostic (2.38e-3)" "unprognostic (2.35e-2)" "unprognostic (2.71e-2)" "unprognostic (2.36e-3)" "unprognostic (8.04e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-3)" "unprognostic (5.19e-2)" 26.9 10.5 6.5 19.2 8.9 20.3 19.9 9.5 9.4 16.0 6.5 17.3 12.0 11.3 15.8 29.5 11.3 11.5 14.9 6.8 8.9 16.7 16.9 16.4 32.1 7.6 8.3 11.4 17.4 16.5 9.2 18.8 7.7 13.4 16.4 14.3 19.4 15.1 15.4 25.4 15.5 11.9 7.0 21.2 13.9 31.5 7.9 20.1 31.0 16.8 35.2 21.0 20.1 8.2 29.1 13.2 23.2 11.7 27.3 23.0 22.5 26.5 33.9 30.6 26.6 8.5 15.8 68.7 13.1 42.1 13.5 45.1 20.1 36.6 33.4 50.2 11.1 10.2 20.4 18.3 28.2 32.7 17.7 20.2 40.3 23.5 34.1 20.3 35.9 20.7 8.0 62.0 28.0 14.0 33.1 18.1 24.2 11.3 17.2 21.8 13.9 27.9 44.5 29.9 25.6 10.8 21.0 21.1 14.7 30.3 10.9 16.3 31.2 31.1 14.1 10.9 24.4 65.1 38.3 52.5 27.4 27.4 19.0 0.0 1.4 0.7 0.6 2.6 0.9 0.7 0.7 1.0 0.8 1.3 0.3 0.6 1.2 0.2 5.0 0.7 1.5 0.4 6.5 8.9 9.5 9.4 6.8 8.9 7.6 8.3 7.7 7.0 7.9 8.2 71.1 28.9 21.0 30.3 44.9 49.3 37.3 21.2 13.1 19.3 46.0 35.3 35.8 24.3 23.0 33.1 16.7 14.3 57.6 51.2 7.9 26.3 1.9 62.1 48.9 38.0 16.3 22.7 42.5 58.4 49.4 32.7 21.9 103.3 8.2 32.0 32.2 25.2 30.3 21.9 38.3 35.9 10.2 142.6 38.7 4.8 25.1 82.2 26.6 43.1 69.3 45.9 8.2 32.2 49.5 54.3 28.0 26.4 53.7 51.5 35.7 23.5 30.0 27.0 26.3 39.0 35.2 6.5 6.1 54.6 62.5 18.3 47.7 43.0 38.7 79.5 MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 82.3;Excitatory neurons: 76.7;Suprabasal keratinocytes: 61.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.3;CACO-2: 45.2;CAPAN-2: 27.9;T-47d: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" 3.8 2.7 0.1 5.7 1.0 8.8 9.7 4.7 2.2 6.4 0.1 10.7 6.0 5.1 1.9 37.1 11.8 6.4 6.6 0.4 0.0 12.2 1.9 10.1 2.6 0.0 0.0 3.4 12.1 11.8 2.2 11.7 0.1 8.0 9.3 9.7 7.6 4.8 13.8 24.8 7.2 8.7 0.0 2.4 8.8 9.0 0.0 3.2 14.4 14.3 6.9 9.7 9.6 1.1 5.9 0.1 0.6 0.0 0.1 0.1 23.3 1.2 0.9 4.7 7.4 45.2 27.9 0.0 0.3 3.4 3.4 10.4 3.9 7.5 10.9 0.0 7.5 0.0 1.3 2.8 0.0 0.0 0.0 0.3 11.6 0.7 0.4 0.0 0.0 2.2 1.1 0.0 6.2 10.9 2.3 0.0 1.4 8.9 2.1 1.2 13.3 0.0 0.4 19.0 1.1 0.0 2.3 11.3 0.0 3.6 89.3 1.1 0.0 1.8 12.5 0.0 1.0 0.2 0.0 0.1 0.1 10.7 0.0 0.0 7.7 9.0 3.8 2.5 5.6 0.6 4.2 2.6 7.8 0.5 7.9 5.7 3.1 5.0 1.5 0.1 1.1 5.1 0.1 1.0 4.7 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.1 1.6 44.8 48.3 10.4 5.5 23.1 10.9 9.5 7.4 1.1 14.7 8.6 12.1 10.0 24.3 14.7 16.7 50.0 9.8 15.3 9.8 5.5 82.3 9.3 0.6 11.7 6.7 4.2 76.7 12.9 3.5 2.6 11.2 6.6 1.3 0.7 2.9 3.2 5.4 3.3 30.3 10.4 8.2 4.7 5.3 20.3 0.9 8.1 7.2 12.2 16.2 24.0 4.1 4.5 2.5 6.6 7.8 0.4 5.1 7.5 12.1 9.5 19.3 8.5 0.0 1.5 7.6 5.4 9.5 48.0 61.1 46.5 16.3 0.1 11.3 17.4 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MUC21 "bCX31G15.2, C6orf205" ENSG00000204544 "Mucin 21, cell surface associated" Q5SSG8 6 30983718-30989903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 135.8;esophagus: 696.3;vagina: 244.5" "Group enriched" "Detected in some" 5 "Club cells: 11.8;Squamous epithelial cells: 37.7;Urothelial cells: 32.0" "Group enriched" "Detected in many" 9 "cervical cancer: 6.8;head and neck cancer: 6.6;lung cancer: 13.9;stomach cancer: 7.0;thyroid cancer: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052028 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA052028: AB_2681700" "unprognostic (2.27e-2)" "unprognostic (4.85e-3)" "unprognostic (5.24e-3)" "unprognostic (1.68e-2)" "unprognostic (2.68e-2)" "unprognostic (2.98e-3)" "unprognostic (1.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" "unprognostic (3.24e-2)" "unprognostic (7.81e-2)" 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 135.8 0.0 0.1 0.0 0.1 0.0 696.3 0.2 0.0 0.1 0.0 0.0 0.1 0.3 1.3 0.0 0.0 0.0 0.2 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 106.8 0.0 0.3 0.2 0.1 0.0 0.0 0.1 1.7 0.1 0.1 0.0 0.1 0.0 13.4 0.2 244.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.2 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.3 0.1 0.0 32.0 MUC22 PBMUCL1 ENSG00000261272 "Mucin 22" E2RYF6 6 31010474-31035402 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 17.8" "Cell type enriched" "Detected in single" 6 "Microglial cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (2.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (9.88e-2)" "unprognostic (1.14e-1)" "unprognostic (3.65e-1)" "unprognostic (1.35e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 35.7;Extravillous trophoblasts: 130.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 14.9;MCF7: 21.2;RH-30: 20.3;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA030972: AB_2673680, HPA030973: AB_10603574, HPA061387: " "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (4.96e-3)" "unprognostic (6.64e-3)" "unprognostic (2.06e-1)" "unprognostic (3.18e-3)" "unprognostic (1.88e-6)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (3.28e-3)" "unprognostic (9.55e-2)" "prognostic favorable (2.38e-4)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 1.9 0.8 1.6 1.0 1.0 2.9 2.5 3.0 3.7 2.6 0.6 1.4 0.5 0.8 0.3 15.7 1.0 0.7 2.3 1.0 2.1 3.1 0.1 3.9 1.8 2.6 1.8 0.5 0.7 4.1 2.2 8.3 2.7 1.0 0.4 4.7 6.8 0.8 4.4 7.8 1.8 0.5 0.2 1.8 2.2 0.9 4.1 0.9 1.4 3.0 2.9 1.4 4.0 2.1 0.1 0.1 2.3 1.7 0.2 0.0 14.9 0.0 0.0 0.0 0.0 3.3 1.1 1.4 2.0 0.0 0.1 4.7 0.4 0.1 0.0 2.5 0.8 4.1 1.8 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.1 0.0 12.0 1.3 2.6 0.9 0.0 21.2 0.2 0.3 11.2 3.6 0.1 11.6 20.3 5.4 1.2 2.4 1.7 0.8 0.6 72.2 4.9 2.8 2.8 0.1 2.4 0.0 1.7 0.0 0.0 3.2 2.3 13.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.1 0.1 0.0 1.6 0.4 1.2 0.0 0.1 0.0 2.1 0.0 0.2 1.6 1.0 3.0 3.7 1.0 2.1 2.6 1.8 2.7 0.2 4.1 2.1 7.8 3.2 0.6 0.0 12.7 9.4 13.1 6.7 4.0 35.7 7.3 3.6 1.7 2.8 3.4 1.8 12.5 3.0 10.4 9.4 13.7 3.4 0.4 1.9 1.1 15.7 4.2 0.0 2.9 0.8 130.4 1.6 6.6 5.8 4.5 0.5 0.4 0.2 2.3 1.7 4.9 3.7 6.1 0.0 1.7 0.8 0.6 1.0 12.4 3.7 1.1 2.0 0.0 0.5 0.2 7.3 8.7 1.9 6.1 10.3 0.1 0.8 0.3 9.2 0.0 2.5 0.7 0.2 8.1 14.1 6.8 23.1 3.0 0.7 3.5 12.1 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.9;Syncytiotrophoblasts: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 391.8;granulocytes: 288.7;monocytes: 594.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 1000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 41.2 36.0 47.0 61.2 48.0 21.9 35.1 49.5 52.1 57.5 47.0 37.7 21.0 33.6 40.6 156.2 29.0 44.1 31.4 46.9 52.9 35.1 42.8 39.6 79.6 50.9 50.4 31.0 42.2 80.7 42.3 44.3 53.7 30.0 34.2 16.5 75.0 37.9 26.6 63.0 33.6 50.1 48.3 88.9 33.9 50.2 49.0 60.8 27.4 32.3 98.4 71.7 59.7 52.1 55.9 39.2 22.6 25.8 114.2 67.5 98.3 119.0 65.5 95.6 86.8 54.3 29.5 30.3 29.3 107.4 113.5 25.7 22.4 43.9 62.7 44.9 16.4 17.0 12.6 37.5 91.6 10.5 37.7 60.7 49.6 101.8 16.4 68.3 107.7 31.7 8.1 34.8 143.4 52.2 28.6 40.2 28.7 53.5 38.4 22.1 64.2 15.8 65.5 91.4 25.1 13.0 35.2 62.1 45.1 50.7 30.4 13.9 66.0 99.0 37.8 36.9 44.8 23.0 24.8 18.0 69.6 31.5 54.5 86.6 594.1 245.1 36.9 526.5 39.2 102.5 44.2 37.0 391.8 103.7 36.7 30.0 288.7 65.3 378.2 318.5 54.7 466.2 47.0 48.0 49.5 52.1 46.9 52.9 50.9 50.4 53.7 48.3 49.0 52.1 22.9 38.5 34.2 15.0 48.6 26.9 28.4 60.8 19.4 46.1 27.4 27.6 18.0 17.2 56.9 38.6 22.9 146.0 67.4 13.9 41.1 66.1 151.3 22.5 26.1 31.7 23.4 12.8 11.5 45.7 144.0 35.6 15.8 24.9 51.9 31.1 30.0 12.9 216.9 47.1 15.2 20.4 28.5 121.8 67.5 33.0 30.1 106.0 39.2 26.2 118.6 45.4 17.5 17.1 24.0 59.1 32.3 37.6 51.2 15.5 23.3 64.7 35.2 55.6 19.7 31.8 37.4 68.0 25.6 39.9 41.6 318.8 29.1 32.2 16.2 34.7 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NLRP2 "CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2" ENSG00000022556 "NLR family pyrin domain containing 2" Q9NX02 19 54953130-55001142 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Extravillous trophoblasts: 216.1;Syncytiotrophoblasts: 97.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 78.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 42.2;BEWO: 177.9;OE19: 79.7;SuSa: 80.3;T-47d: 46.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021183 Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA021183: AB_2670615" "unprognostic (1.66e-2)" "unprognostic (9.28e-2)" "unprognostic (6.60e-2)" "unprognostic (6.50e-3)" "unprognostic (1.09e-2)" "unprognostic (4.57e-3)" "unprognostic (4.27e-1)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.63e-1)" "unprognostic (2.34e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.86e-2)" "unprognostic (7.57e-2)" 0.4 0.3 0.9 2.7 0.6 1.0 1.0 0.0 0.8 2.6 0.1 1.7 1.8 1.1 1.8 7.9 1.9 0.9 0.4 0.7 0.1 1.9 0.4 1.6 2.1 0.1 0.2 0.3 1.6 0.4 1.2 7.1 0.1 1.5 1.9 3.1 2.4 1.1 0.6 3.0 1.7 0.8 0.0 2.1 2.5 7.2 0.3 3.4 4.4 0.0 1.9 7.1 4.3 0.2 20.4 42.2 15.8 0.4 0.2 0.1 177.9 0.1 0.0 0.6 0.2 35.9 0.7 14.7 0.1 0.1 0.1 8.1 0.0 24.4 0.3 1.7 0.2 9.8 0.5 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.1 0.1 0.9 0.0 32.7 0.2 0.0 0.3 0.1 1.3 5.0 79.7 0.0 8.8 0.0 24.0 26.4 0.7 5.3 0.7 0.0 8.1 0.0 80.3 46.7 0.2 0.0 0.3 0.7 0.4 0.3 5.2 16.6 0.7 0.4 1.0 0.0 0.1 0.2 0.0 1.8 0.3 1.3 0.6 0.4 0.7 0.2 0.6 0.3 0.8 0.2 3.0 0.1 1.0 1.3 0.4 0.9 0.6 0.0 0.8 0.7 0.1 0.1 0.2 0.1 0.0 0.3 0.2 0.0 9.6 7.3 0.3 1.5 0.5 1.9 8.1 0.0 2.7 1.9 1.5 0.8 4.3 10.1 1.8 4.2 45.2 3.5 2.9 0.0 5.3 23.1 8.6 1.3 0.7 2.4 0.8 3.0 1.9 216.1 1.1 2.0 13.1 4.5 0.7 0.0 0.0 11.6 0.0 1.9 3.0 6.1 0.3 0.5 7.2 0.9 1.1 0.0 0.0 3.0 0.7 8.2 0.5 0.5 6.7 1.0 0.0 1.5 2.5 0.8 0.4 8.4 2.7 0.0 0.3 0.8 16.8 11.7 0.0 1.3 97.3 2.4 0.3 3.0 4.7 NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 43.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061516 Supported Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Plasma membrane, Cell Junctions" "HPA061516: AB_2684548" "unprognostic (7.58e-2)" "unprognostic (3.71e-1)" "unprognostic (6.36e-2)" "prognostic favorable (2.47e-5)" "unprognostic (5.60e-3)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (8.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.59e-6)" "unprognostic (3.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (4.22e-2)" 8.1 10.7 4.9 4.7 5.0 6.5 7.0 4.7 5.5 10.5 6.4 10.8 4.8 10.1 3.4 43.2 9.8 5.2 17.0 4.7 4.6 8.8 9.1 5.5 5.0 5.3 5.1 4.0 9.6 6.0 4.8 4.2 5.4 8.3 3.4 2.7 10.3 6.8 24.1 21.5 6.4 5.8 5.1 8.1 7.3 3.5 5.1 4.7 7.9 13.7 10.5 9.6 16.5 5.2 5.3 15.6 1.6 12.2 5.1 5.9 2.4 7.0 8.0 3.4 5.9 0.9 13.0 9.5 21.0 8.9 5.1 13.1 4.7 4.0 1.1 12.5 5.0 12.6 5.5 8.6 7.7 4.4 7.0 6.6 16.4 4.5 8.7 6.9 7.0 12.5 0.1 6.2 3.6 14.2 7.5 10.7 7.5 6.9 8.6 14.6 2.1 3.1 8.2 6.8 2.3 7.9 10.4 5.5 4.5 2.4 17.7 13.0 8.2 6.8 6.0 6.1 3.6 2.2 2.6 3.3 1.0 13.4 4.9 2.8 3.5 15.4 0.8 1.5 1.0 0.5 0.8 1.2 2.1 0.4 0.9 1.0 8.1 1.4 1.4 0.9 1.4 2.3 4.9 5.0 4.7 5.5 4.7 4.6 5.3 5.1 5.4 5.1 5.1 5.2 3.0 0.0 7.9 5.9 3.2 2.5 1.7 4.5 2.8 1.3 4.1 4.2 12.8 2.8 4.2 7.3 2.1 3.6 1.4 7.3 1.9 7.1 2.0 8.7 2.8 3.8 2.4 3.8 5.9 3.8 2.2 3.5 8.2 4.1 0.0 5.7 5.3 10.2 6.5 0.0 4.0 3.7 2.0 6.0 1.8 4.7 1.2 4.0 1.8 2.8 6.2 6.1 5.2 5.5 2.8 5.5 7.6 1.2 1.8 1.6 3.9 5.3 7.2 3.2 0.0 2.9 2.7 1.9 2.0 10.8 4.7 0.5 2.8 2.1 5.5 1.2 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 46.9;Endometrial ciliated cells: 45.3;Glandular and luminal cells: 52.4;Intestinal goblet cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 44.1;RPMI-8226: 36.1;RPTEC TERT1: 40.9;SuSa: 45.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 2.1 3.7 1.3 7.7 1.9 11.4 0.9 4.6 1.7 31.0 3.2 8.0 16.5 1.6 1.3 56.7 4.0 1.7 1.2 1.2 1.3 28.2 5.1 10.3 11.5 2.1 1.8 1.3 16.0 0.8 3.0 4.4 2.0 1.9 8.8 0.5 15.1 1.6 0.7 22.4 12.5 1.2 1.4 13.1 2.5 3.7 2.2 3.9 16.1 1.1 8.0 3.1 45.3 4.1 4.3 23.1 13.7 0.6 0.3 0.6 44.1 5.5 5.7 14.7 5.9 24.4 0.8 7.0 3.2 1.5 24.1 8.3 3.2 8.3 6.3 0.0 0.4 0.0 1.4 4.2 9.3 0.0 0.1 2.6 6.1 8.6 5.0 3.3 0.7 0.0 0.9 1.7 2.8 1.0 0.0 0.1 8.9 3.1 0.7 0.0 1.0 36.1 40.9 0.1 2.1 0.2 1.6 6.5 0.7 45.6 6.6 0.1 1.7 5.3 2.5 0.6 8.7 12.1 2.0 4.4 0.8 0.0 2.1 11.2 16.5 40.1 10.3 11.8 7.6 37.9 12.7 12.3 10.4 39.3 27.9 21.9 120.4 17.5 13.1 4.1 8.1 17.4 1.3 1.9 4.6 1.7 1.2 1.3 2.1 1.8 2.0 1.4 2.2 4.1 2.0 6.4 6.8 0.3 28.0 1.1 3.2 3.7 13.1 1.1 1.9 2.2 2.7 20.0 2.9 33.1 0.0 9.2 7.1 34.9 5.9 46.9 2.0 45.3 7.5 5.9 10.8 2.7 0.1 1.8 29.1 3.7 7.7 52.4 0.0 2.4 0.7 2.6 4.7 0.0 0.4 43.0 18.3 12.3 11.1 2.1 0.0 8.9 7.2 3.7 38.5 1.3 18.6 0.5 3.5 6.9 7.8 0.0 18.5 2.5 18.3 17.2 7.7 0.5 6.6 2.4 5.5 0.9 1.1 21.5 5.4 4.1 5.7 0.5 22.0 0.5 ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" 37.5 38.1 14.6 24.2 17.0 20.4 31.3 18.3 20.5 30.0 24.7 44.5 27.2 28.4 51.3 75.9 26.3 20.6 30.1 14.8 18.4 40.7 47.5 35.5 23.0 19.0 18.0 16.8 32.9 44.5 29.7 22.3 18.5 30.8 48.4 14.8 40.2 23.2 19.7 36.4 30.2 26.4 17.2 33.2 32.9 42.7 18.3 27.6 27.4 11.1 38.5 41.7 36.8 20.2 55.9 103.5 43.1 22.4 81.2 40.4 47.7 66.5 66.0 57.0 49.9 116.6 133.8 34.5 69.3 80.7 58.5 100.3 34.6 138.7 56.6 35.9 51.4 46.7 89.7 65.9 85.8 56.7 47.4 50.9 125.2 99.9 103.3 73.3 81.0 38.2 25.0 91.1 73.7 89.3 34.8 25.3 20.9 87.8 82.0 22.8 34.5 88.4 149.8 159.1 37.4 23.8 84.9 99.9 38.4 64.8 120.0 40.1 59.4 30.5 42.6 36.4 42.7 43.6 39.1 28.1 48.9 22.4 43.1 50.4 73.0 107.1 86.5 92.8 76.8 93.2 82.1 92.1 73.4 76.1 67.8 81.5 91.8 74.1 108.7 119.9 107.8 72.1 14.6 17.0 18.3 20.5 14.8 18.4 19.0 18.0 18.5 17.2 18.3 20.2 43.1 73.7 38.3 1.3 39.8 23.3 71.9 132.9 15.4 9.9 43.1 30.0 3.9 45.8 99.4 53.3 12.5 74.7 49.6 125.7 29.4 133.7 171.0 77.9 25.7 42.0 46.1 26.5 0.7 168.1 117.5 22.0 28.1 86.0 51.9 14.0 35.3 82.2 125.3 8.4 0.8 66.7 69.2 42.5 49.1 68.0 25.4 57.4 56.9 2.8 111.4 24.8 77.2 1.0 4.0 197.4 133.5 23.3 50.8 95.7 89.7 76.0 149.2 18.4 19.7 13.5 32.9 107.0 61.7 50.6 33.4 151.6 44.6 30.5 56.2 91.3 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 25.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Cholangiocytes: 21.5;Distal enterocytes: 25.4;Kupffer cells: 21.1;Squamous epithelial cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.6" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.6" "Cell line enriched" "Detected in many" 5 "HEL: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015577 Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" 1.6 1.4 6.2 2.3 14.2 5.7 1.4 3.1 6.4 4.5 1.0 9.1 3.2 6.5 0.5 19.2 2.1 2.0 2.9 5.9 6.7 0.8 1.5 7.0 0.8 3.3 4.2 8.8 3.3 0.3 1.6 25.4 8.4 7.7 6.7 9.0 3.2 2.2 7.7 8.9 6.1 4.5 4.9 2.2 0.9 1.1 8.2 1.6 1.3 3.4 2.7 2.4 8.0 4.1 0.0 0.7 7.0 0.0 1.1 0.1 0.0 0.0 0.1 0.2 0.6 9.0 0.1 0.0 0.7 0.0 1.1 1.5 3.9 1.3 0.3 0.0 3.4 45.9 0.1 0.0 0.0 5.4 4.0 0.5 8.7 0.0 0.4 3.5 0.0 1.5 1.4 0.0 0.0 0.1 0.8 0.1 6.4 0.0 5.5 0.0 0.2 1.3 0.0 3.1 1.1 0.0 0.0 0.0 0.9 1.6 0.0 2.4 0.0 0.7 1.8 0.0 3.9 0.0 0.0 0.0 4.5 0.0 5.2 6.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.1 6.2 14.2 3.1 6.4 5.9 6.7 3.3 4.2 8.4 4.9 8.2 4.1 1.0 0.0 0.5 12.7 0.8 1.9 6.7 3.3 15.9 23.3 0.5 0.1 7.1 21.5 1.0 0.0 0.0 0.2 1.6 25.4 0.0 1.3 0.2 1.9 12.0 7.1 0.0 10.8 0.0 0.0 0.3 5.6 0.0 2.7 10.1 0.1 11.7 0.3 7.4 0.0 0.2 8.9 0.0 21.1 0.3 0.8 14.9 15.9 0.0 1.0 1.8 19.1 0.0 0.0 0.6 0.9 12.3 6.0 0.0 6.3 13.4 0.2 0.2 1.5 0.0 1.2 1.0 0.4 2.2 45.4 2.0 0.1 0.5 3.5 8.3 4.9 PADI1 "HPAD10, PAD1, PDI, PDI1" ENSG00000142623 "Peptidyl arginine deiminase 1" Q9ULC6 1 17205128-17246007 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "esophagus: 109.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.8;Extravillous trophoblasts: 14.0;Squamous epithelial cells: 5.6;Urothelial cells: 22.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.2;EFO-21: 2.1;HaCaT: 1.5;RPTEC TERT1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA062294 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA062294: AB_2684741" "unprognostic (9.30e-2)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.40e-1)" "unprognostic (5.22e-2)" "unprognostic (7.27e-2)" "unprognostic (3.84e-1)" "unprognostic (3.37e-2)" "unprognostic (1.41e-1)" "unprognostic (7.75e-2)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "prognostic unfavorable (8.34e-11)" "unprognostic (2.00e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 0.0 109.5 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.2 0.0 0.0 11.5 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.4 1.4 18.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 4.2 0.0 2.1 0.1 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.6 0.9 0.0 0.0 14.8 0.0 3.9 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 14.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.8 0.0 0.0 0.6 0.3 0.0 0.0 0.3 0.2 0.1 5.6 0.0 0.7 0.0 0.1 0.6 22.5 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 17.0;urinary bladder: 25.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Ionocytes: 6.1;Squamous epithelial cells: 1.1;Urothelial cells: 7.9" "Cancer enriched" "Detected in many" 4 "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 14.0;RT4: 17.4;T-47d: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 17.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.9 3.4 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 25.6 3.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 14.0 0.0 1.4 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.5 0.1 0.1 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 7.9 PAX9 ENSG00000198807 "Paired box 9" P55771 14 36657568-36679362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 81.0;lymphoid tissue: 20.5;parathyroid gland: 43.0;salivary gland: 51.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 45.3;Basal squamous epithelial cells: 174.8;Ionocytes: 40.7;Squamous epithelial cells: 172.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.3;HDLM-2: 58.3;PC-3: 18.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001572, CAB016239" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli Nucleoplasm "CAB016239: AB_2159984, HPA001572: " "unprognostic (3.09e-1)" "prognostic favorable (5.38e-4)" "unprognostic (1.56e-2)" "unprognostic (2.80e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-2)" "unprognostic (5.93e-3)" "unprognostic (2.71e-3)" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (2.41e-2)" "unprognostic (9.44e-2)" "unprognostic (2.31e-4)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" 0.1 0.1 0.0 0.1 0.0 0.3 0.6 0.0 0.0 7.3 0.1 0.7 0.0 0.2 0.3 81.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 43.0 2.2 0.0 0.0 3.7 0.1 0.0 51.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 20.5 0.7 0.0 8.5 0.7 7.1 0.0 5.3 2.3 0.0 2.5 2.1 3.8 2.0 0.0 0.3 0.0 0.0 1.6 1.8 1.6 0.8 0.0 0.5 11.4 2.1 12.3 0.0 58.3 7.3 0.9 1.2 0.0 0.0 0.0 4.2 0.7 6.0 0.0 1.9 0.0 0.0 5.3 2.3 0.3 0.2 7.3 0.9 0.0 0.1 1.9 18.9 0.0 0.0 0.0 0.0 6.9 3.4 0.0 1.3 7.0 1.4 0.9 5.1 0.0 0.0 0.0 0.6 2.2 1.0 0.0 0.1 4.4 0.7 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.4 45.3 174.8 0.0 1.6 1.3 0.4 0.0 25.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 40.7 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 20.9 0.0 0.0 26.8 0.0 0.0 0.1 2.0 2.4 0.9 172.0 0.3 0.1 0.1 0.0 0.6 12.1 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826660-37862937 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 334.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" NA NA 1700000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favorable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 8.2 11.2 3.2 9.5 3.2 10.1 8.8 4.6 4.5 10.9 4.5 9.8 7.6 10.1 4.9 36.6 7.9 11.3 5.6 4.9 3.1 8.0 14.8 6.9 10.0 3.4 3.0 6.9 4.4 8.4 3.0 11.7 3.6 7.8 9.0 18.2 7.7 5.2 1.2 17.5 7.8 13.7 3.5 8.3 6.1 5.3 3.1 10.2 9.7 1.9 22.7 18.9 16.4 3.7 27.4 9.5 14.6 16.6 10.2 12.4 19.8 32.6 18.9 27.8 26.4 18.0 19.2 38.0 15.5 17.8 34.9 13.8 36.0 32.0 65.1 23.0 21.0 40.1 15.2 12.3 23.2 44.2 26.5 17.0 36.0 22.0 18.6 16.2 41.6 31.2 53.6 6.2 24.3 15.6 49.8 49.6 17.3 19.2 15.5 35.8 23.1 14.8 15.7 52.3 31.8 10.8 17.5 23.3 12.0 19.5 21.5 45.4 37.0 19.7 24.9 27.3 67.1 14.0 38.4 40.3 10.9 56.2 32.9 19.8 27.5 67.2 9.8 22.4 11.5 9.4 8.0 11.1 31.9 5.5 7.7 9.8 33.6 28.1 18.2 7.1 14.9 17.0 3.2 3.2 4.6 4.5 4.9 3.1 3.4 3.0 3.6 3.5 3.1 3.7 16.9 0.0 8.2 5.2 13.8 14.7 14.3 32.9 17.6 7.8 12.6 6.9 4.5 14.3 23.1 3.7 0.0 31.9 11.9 10.6 5.9 16.0 0.9 9.0 12.7 22.9 7.2 8.0 8.3 11.8 37.8 10.3 5.6 14.7 12.7 56.4 42.5 9.7 37.9 6.7 5.6 9.2 4.1 24.4 15.2 2.0 8.4 24.5 5.4 4.7 46.1 334.1 13.4 8.0 0.9 14.5 6.7 9.8 10.5 17.7 6.9 10.4 9.8 16.0 13.1 5.8 23.8 0.6 2.1 42.5 32.1 79.8 14.7 19.8 12.9 20.4 PHACTR4 "FLJ13171, PPP1R124" ENSG00000204138 "Phosphatase and actin regulator 4" Q8IZ21 1 28369582-28500364 "Predicted intracellular proteins" Neurogenesis "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 212.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028985 Approved Approved "Plasma membrane,Intermediate filaments,Cytosol" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA028985: AB_10602142" "unprognostic (1.55e-1)" "unprognostic (2.61e-2)" "unprognostic (4.50e-3)" "unprognostic (1.73e-1)" "unprognostic (5.27e-1)" "prognostic favorable (1.05e-4)" "unprognostic (9.65e-3)" "unprognostic (8.77e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.94e-2)" "unprognostic (3.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.03e-2)" "unprognostic (2.26e-2)" 7.2 6.5 6.3 8.6 8.1 11.8 10.1 8.2 6.8 13.6 10.2 12.9 9.1 13.7 7.1 33.0 13.2 8.9 8.9 5.8 8.5 14.1 16.3 12.4 7.8 9.1 6.8 13.1 11.7 15.1 4.0 10.4 7.2 11.8 14.1 5.1 11.3 8.2 11.9 16.2 10.3 13.8 5.5 12.0 10.7 8.6 8.0 11.9 12.4 18.3 12.2 9.4 14.8 9.3 26.0 17.2 37.8 27.5 9.6 10.2 5.8 18.1 18.3 38.5 40.0 16.4 28.1 24.5 15.9 21.6 24.3 17.7 26.3 17.4 33.9 18.1 14.9 51.6 28.2 26.5 14.3 31.2 56.7 9.9 16.4 24.7 42.7 14.0 52.0 19.5 26.0 16.9 24.5 8.0 22.3 7.8 28.3 14.0 11.8 23.2 35.7 18.5 20.2 22.8 20.1 26.0 41.0 16.9 20.9 14.9 22.5 11.1 33.3 18.8 34.6 13.4 35.8 12.4 19.7 20.1 18.4 26.2 20.3 1.9 2.0 2.0 3.3 2.0 2.9 1.4 2.6 3.3 2.2 2.2 1.8 2.6 1.4 2.4 3.3 2.6 1.2 1.5 6.3 8.1 8.2 6.8 5.8 8.5 9.1 6.8 7.2 5.5 8.0 9.3 65.9 70.5 49.8 60.7 38.9 38.6 23.6 24.1 46.7 34.6 37.0 35.8 38.5 40.0 53.7 23.9 20.9 17.6 36.7 59.9 17.6 32.4 6.1 125.6 58.6 56.2 49.3 32.2 65.8 36.5 17.3 29.1 35.2 212.6 48.0 38.8 42.5 63.3 22.8 23.5 82.6 57.0 24.4 33.6 32.3 8.5 19.3 40.3 17.8 92.8 33.7 19.8 51.5 117.1 148.1 48.2 33.5 29.7 30.8 24.4 40.0 45.5 63.3 39.8 39.5 45.6 31.0 47.1 39.4 62.1 54.1 15.2 35.7 15.3 50.6 30.9 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 159.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1438.7;Basal squamous epithelial cells: 582.8;Urothelial cells: 760.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 296.3;RPTEC TERT1: 233.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 21.3 31.0 9.9 17.3 10.1 21.8 28.1 8.9 11.0 23.1 6.2 8.9 6.5 13.4 4.4 59.8 7.8 39.3 20.6 10.3 11.3 14.8 67.6 27.1 5.9 10.8 16.9 19.2 17.9 5.3 8.2 14.3 11.3 8.9 10.2 13.8 159.1 8.2 5.8 11.5 8.6 14.8 9.6 19.5 22.5 3.1 11.5 7.4 27.2 1.5 7.5 60.9 33.7 11.3 60.9 71.5 54.9 30.4 25.0 51.6 3.9 50.5 134.7 22.4 30.8 39.7 72.2 0.3 14.8 21.2 73.8 30.7 1.5 84.2 47.9 9.3 1.2 1.5 3.8 68.2 36.3 1.4 15.1 16.2 60.6 93.2 182.6 296.3 54.4 0.1 5.0 1.7 115.8 7.8 0.2 7.9 20.1 36.3 108.7 0.2 14.3 1.8 233.7 135.1 4.0 10.4 8.8 0.8 169.5 67.8 35.5 0.7 50.8 75.8 7.2 89.3 50.4 0.8 0.3 0.2 127.9 0.8 96.7 0.2 0.0 0.0 0.9 0.1 1.5 0.0 0.9 1.0 0.0 0.0 0.1 0.2 0.2 0.0 1.1 0.0 1.6 0.2 9.9 10.1 8.9 11.0 10.3 11.3 10.8 16.9 11.3 9.6 11.5 11.3 98.5 12.8 12.4 7.2 13.0 195.3 1438.7 249.6 582.8 5.2 136.2 140.3 34.8 11.5 44.4 31.3 2.1 4.7 42.9 11.6 84.1 74.8 2.2 11.5 111.2 162.5 117.7 0.0 7.8 43.1 11.5 203.2 55.0 20.4 79.5 7.1 21.4 127.8 94.7 1.7 14.6 41.0 384.5 14.0 123.4 2.1 9.3 110.8 286.4 8.4 24.0 97.8 0.0 142.2 2.7 208.4 27.7 15.4 19.0 116.1 0.2 39.3 12.4 5.2 269.5 59.8 276.3 0.7 3.2 66.3 75.6 7.4 132.8 20.7 18.0 760.3 PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2267.8;lymphoid tissue: 2103.1;vagina: 1595.8" "Group enriched" "Detected in many" 10 "Basal respiratory cells: 5354.5;Club cells: 2170.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 22 "cerebral cortex: 12.0;pons: 7.3;thalamus: 19.0" "Immune cell enriched" "Detected in some" 1021 "neutrophil: 1763.3" "Lineage enriched" "Detected in single" 4377 "granulocytes: 1763.3" "Group enriched" "Detected in many" 5 "EFO-21: 89.3;HaCaT: 109.8;OE19: 103.7;PC-3: 189.9" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 1400000 "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" 6.1 0.7 0.2 101.9 0.5 1.8 8.8 0.2 12.0 180.1 1.2 124.3 1.9 2.3 1.1 2267.8 4.8 56.6 1.7 0.2 0.4 1.5 3.3 32.5 0.4 0.3 0.3 0.7 1.6 0.2 2.8 1.1 7.3 11.7 43.3 0.0 460.8 3.5 0.6 78.6 42.3 7.5 0.3 20.0 9.0 0.5 19.0 90.6 0.8 1.9 2103.1 44.7 1595.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.4 0.0 3.1 2.1 1.4 89.3 0.0 1.1 109.8 0.0 23.2 0.1 1.2 0.0 0.5 6.3 0.9 0.0 0.7 0.0 0.0 21.7 17.8 1.9 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.1 0.2 103.7 189.9 0.0 1.0 0.0 21.9 0.4 0.0 0.0 15.7 2.1 0.1 0.0 0.0 0.0 0.8 1.0 10.9 0.3 0.9 0.3 1.8 0.4 14.3 0.7 0.1 0.3 0.4 1.7 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1763.3 0.0 0.1 0.1 0.1 0.6 0.2 0.5 0.2 12.0 0.2 0.4 0.3 0.3 7.3 0.3 19.0 0.3 0.1 0.0 8.6 0.0 7.4 0.1 4.7 5354.5 0.0 0.0 39.4 8.4 0.2 8.6 2170.2 18.4 0.0 0.2 0.5 375.4 0.0 46.6 0.1 3.7 0.7 3.0 16.6 0.0 0.0 317.3 0.0 0.8 2.6 6.9 4.5 0.0 0.0 0.0 0.1 0.0 0.0 31.8 197.4 0.0 0.4 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.8 219.6 0.0 0.2 29.1 33.9 0.2 152.9 0.0 0.0 0.0 50.5 0.0 0.0 36.2 3.8 0.0 2.5 0.1 154.1 150.4 PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 121.0;Basal squamous epithelial cells: 409.2;Squamous epithelial cells: 1069.0;Urothelial cells: 257.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 141.4;HeLa: 108.9;K-562: 112.1;T-47d: 157.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" 1.5 1.9 0.7 7.7 0.6 0.3 0.6 0.9 0.7 83.5 4.7 11.4 12.1 0.8 0.0 711.6 0.5 1.1 0.2 0.9 1.1 0.1 0.3 0.4 0.1 0.8 0.9 0.6 0.4 0.0 164.7 2.7 0.7 20.1 2.0 0.1 137.5 0.0 14.1 2.0 7.9 0.4 0.5 0.2 41.9 2.2 0.7 0.0 0.2 20.1 12.6 85.0 199.0 0.8 57.5 36.9 0.0 44.7 1.4 0.9 13.4 9.6 14.6 5.1 2.3 141.4 32.5 59.9 17.6 0.9 12.6 17.6 6.4 25.5 0.3 0.7 48.2 13.4 108.9 38.4 15.6 5.8 0.1 1.4 18.4 0.0 4.9 0.3 0.1 10.1 112.1 0.2 1.9 18.4 0.6 12.3 0.1 4.8 31.8 18.5 1.1 1.2 0.6 17.9 20.2 0.1 48.4 24.1 0.0 0.5 157.5 4.2 1.5 6.1 13.4 3.5 17.0 0.1 0.2 40.7 8.1 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.7 0.9 1.1 0.8 0.9 0.7 0.5 0.7 0.8 0.1 0.0 0.0 0.0 0.2 1.3 121.0 12.8 409.2 1.0 2.5 2.7 2.3 1.5 8.6 0.0 0.0 0.8 0.0 4.2 0.0 0.2 4.2 0.3 0.6 1.2 0.0 50.8 0.0 0.4 2.1 28.8 0.5 0.2 0.0 2.7 0.0 0.0 0.9 0.0 0.0 2.4 6.1 0.0 0.3 5.7 0.3 1.0 0.0 0.0 0.0 0.4 1.0 0.0 0.1 16.9 3.4 0.0 3.1 101.6 0.3 0.2 6.1 1.8 0.0 2.1 4.5 2.2 5.6 1069.0 6.8 7.7 0.9 0.7 2.5 257.3 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 44.3 57.9 34.8 43.2 34.7 63.2 42.5 35.9 38.7 42.8 41.0 49.8 47.0 39.6 47.1 88.3 35.9 32.5 45.6 34.0 35.7 49.9 83.2 46.2 58.6 35.5 34.9 29.4 41.0 46.4 33.5 49.6 35.3 37.8 35.2 18.1 44.0 28.5 60.8 60.8 49.0 32.8 35.6 62.5 49.2 65.4 38.4 61.2 35.4 30.2 63.7 56.3 48.9 36.4 132.7 145.9 95.5 134.0 88.4 73.8 148.5 115.8 127.7 148.7 163.8 129.5 167.9 102.7 145.2 137.0 95.5 105.9 119.3 143.2 87.0 130.1 213.0 70.5 86.0 290.4 133.5 100.1 126.8 107.9 124.7 135.9 85.5 88.4 174.9 130.5 139.6 91.0 115.1 382.2 174.4 180.7 182.2 104.7 77.1 190.9 99.4 180.4 142.5 134.5 91.9 136.8 57.1 169.1 101.8 79.4 156.0 166.0 113.3 86.4 90.4 70.6 90.8 155.4 183.8 122.4 123.1 126.9 107.0 100.6 103.5 236.1 66.5 113.2 47.7 68.5 69.6 74.2 115.8 88.3 62.0 54.1 215.2 51.7 100.1 90.6 95.1 48.3 34.8 34.7 35.9 38.7 34.0 35.7 35.5 34.9 35.3 35.6 38.4 36.4 87.8 51.3 33.4 10.7 85.8 147.2 121.7 206.9 71.2 23.3 94.2 82.8 11.1 82.9 133.5 77.3 29.2 313.7 106.0 217.0 158.5 226.9 156.9 80.5 55.5 91.7 125.6 89.2 8.0 193.3 335.3 66.7 106.0 85.2 69.2 66.7 74.6 94.2 239.3 35.3 8.6 159.3 193.3 105.4 138.4 143.8 62.7 124.4 80.0 9.4 221.1 61.1 118.4 8.0 12.9 345.5 220.8 52.3 97.6 161.3 191.0 198.6 119.7 29.5 72.3 43.4 85.9 228.5 157.8 113.2 172.5 421.0 93.0 61.7 175.9 227.2 PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA040905: AB_10794869, HPA041089: AB_10805836" "unprognostic (1.76e-1)" "unprognostic (5.33e-2)" "unprognostic (1.40e-2)" "unprognostic (5.14e-2)" "unprognostic (3.74e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-3)" "unprognostic (9.36e-2)" "unprognostic (1.16e-2)" "unprognostic (4.00e-3)" "unprognostic (3.13e-3)" "unprognostic (4.15e-1)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" 20.7 16.2 16.7 16.8 19.1 32.0 18.8 18.7 17.8 27.2 19.1 24.7 23.2 20.8 17.1 70.7 21.1 20.7 20.7 15.6 17.4 19.6 15.3 34.6 13.0 17.7 17.2 17.0 19.9 23.5 11.7 29.0 17.7 16.6 19.7 13.3 23.3 16.9 16.2 26.1 26.1 23.3 16.9 18.4 24.4 35.7 17.0 19.9 18.7 17.4 24.9 40.7 35.7 20.6 70.3 48.5 115.0 31.6 22.3 33.7 58.3 66.9 44.7 64.9 62.3 44.1 39.6 34.0 47.6 66.1 55.0 29.4 54.0 99.4 87.0 39.8 21.8 32.2 35.0 32.0 34.7 83.0 46.7 30.3 62.8 56.1 52.9 48.5 75.3 22.6 47.5 29.8 70.9 34.5 58.1 31.7 46.1 97.5 30.3 71.5 69.2 21.4 54.6 96.5 33.6 39.5 79.3 35.3 26.4 73.3 19.3 31.5 81.3 113.6 70.2 59.3 83.5 26.5 39.7 60.7 42.5 34.0 52.5 14.6 6.1 10.9 3.9 4.7 5.0 3.8 4.3 3.9 7.0 1.8 1.4 3.2 36.1 4.1 4.7 2.9 4.6 3.5 16.7 19.1 18.7 17.8 15.6 17.4 17.7 17.2 17.7 16.9 17.0 20.6 26.4 99.3 76.1 35.9 11.9 40.4 26.5 30.8 42.7 19.6 20.7 14.7 21.4 7.2 55.4 22.0 10.4 27.0 12.0 31.2 5.9 23.8 77.3 48.1 26.7 29.5 17.4 15.6 43.0 34.9 15.9 19.3 45.3 54.0 3.8 27.0 26.0 12.2 16.8 33.7 54.9 16.4 8.2 19.6 16.7 57.2 17.4 20.7 14.2 34.7 20.5 10.6 13.4 61.9 66.5 49.8 16.2 11.7 10.8 21.0 23.7 10.0 58.9 19.3 13.1 16.5 22.1 20.4 12.3 52.0 42.5 23.0 12.9 9.2 13.6 68.4 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cell line enhanced" "Detected in many" "Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 6.6 2.1 1.6 20.0 1.6 20.3 6.8 5.5 1.8 15.7 3.1 15.2 9.2 17.2 1.3 55.2 5.5 12.7 1.7 1.5 2.8 2.5 4.5 10.1 15.9 3.2 1.8 4.9 1.9 2.5 1.4 5.1 2.7 3.4 17.2 1.3 9.3 2.4 4.3 9.1 12.6 5.5 2.4 13.6 15.2 1.2 2.9 4.2 9.0 2.2 27.8 19.6 20.2 3.4 1.4 0.5 1.1 0.0 1.6 2.1 0.2 7.2 23.3 2.3 3.7 1.4 9.2 2.0 0.4 13.8 0.3 0.5 0.0 3.6 2.5 21.7 0.1 0.4 4.9 0.0 3.6 0.8 1.6 2.3 11.6 3.3 9.7 0.7 2.9 1.0 1.4 212.1 0.4 0.0 0.1 0.5 0.8 1.4 0.0 0.5 0.0 42.4 2.1 0.3 0.0 0.3 1.0 0.9 0.0 1.6 1.0 2.4 1.5 3.1 1.8 2.1 7.2 81.5 57.0 4.9 5.1 1.3 2.1 2.4 0.8 11.1 22.1 1.2 34.0 2.5 20.5 20.2 0.5 1.0 1.8 11.3 12.5 4.7 0.3 0.4 29.4 2.6 1.6 1.6 5.5 1.8 1.5 2.8 3.2 1.8 2.7 2.4 2.9 3.4 93.1 0.0 5.1 0.3 42.1 19.5 8.6 15.0 3.4 0.6 2.8 3.4 1.5 0.0 19.1 3.7 52.1 0.7 199.8 129.8 0.0 0.3 0.9 15.9 101.0 41.1 1.8 6.1 1.8 0.2 0.7 18.5 19.4 62.6 3.8 9.9 6.4 2.5 19.8 0.0 19.2 15.0 10.2 38.0 199.2 0.3 0.0 64.5 37.4 23.4 30.4 0.5 89.6 0.5 0.1 7.8 103.7 1.2 786.9 4.0 3.2 0.3 13.0 1.1 0.0 5.3 30.1 0.5 2.3 43.9 41.5 0.7 184.3 1.6 8.7 91.9 PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Club cells: 39.9;Collecting duct cells: 33.1;Squamous epithelial cells: 37.2;Urothelial cells: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 79.5;CAPAN-2: 135.9;HaCaT: 73.2;hTCEpi: 78.4;MCF7: 62.1;RT4: 83.8;SK-BR-3: 117.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" 0.7 0.3 1.1 1.5 1.3 0.3 10.3 1.0 2.1 16.6 0.2 11.4 10.5 1.9 27.9 88.1 5.5 27.0 1.1 0.9 0.6 32.4 0.8 1.7 0.1 1.4 0.7 1.1 10.2 25.5 1.5 4.5 1.2 24.7 9.8 0.4 35.2 27.7 0.7 60.0 4.8 0.8 0.3 0.6 26.3 0.6 1.4 2.0 11.9 0.2 7.9 25.7 37.9 2.1 79.5 0.1 0.2 0.8 0.3 0.1 38.5 0.1 0.2 0.3 0.4 0.8 135.9 0.0 0.0 0.1 0.1 73.2 0.0 42.4 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 78.4 0.1 0.4 1.9 0.0 0.1 0.0 0.1 0.0 62.1 0.4 0.5 0.1 3.7 0.5 0.2 0.0 0.1 0.2 83.8 0.6 0.2 0.0 117.7 0.1 0.9 37.2 0.1 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.0 2.1 0.9 0.6 1.4 0.7 1.2 0.3 1.4 2.1 0.4 3.2 4.2 1.3 0.1 6.6 25.2 27.6 14.2 0.4 29.1 14.9 1.7 37.1 39.9 33.1 4.2 19.0 0.1 8.0 11.7 15.6 0.5 2.7 0.6 0.9 3.6 0.0 0.6 11.0 3.5 0.6 25.5 5.5 0.0 0.7 0.0 0.0 2.4 0.0 1.2 10.4 12.2 0.0 0.8 1.4 0.3 0.2 7.2 0.0 0.6 0.1 0.0 1.5 3.2 17.5 12.4 0.7 0.0 14.1 0.7 0.1 12.3 1.1 0.0 0.4 2.2 0.6 0.1 37.2 12.8 11.2 0.2 0.8 17.4 37.5 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 221.0;Club cells: 343.9;Ionocytes: 207.5;Pancreatic endocrine cells: 380.6;Urothelial cells: 479.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 17.3;MCF7: 14.6;RT4: 10.4;SK-BR-3: 22.9" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 23.4 0.0 0.5 0.3 0.7 0.4 79.6 1.3 0.8 0.0 0.0 0.0 16.7 0.5 2.9 0.0 0.0 0.0 0.0 5.8 1.5 2.4 1.1 0.0 6.0 0.5 0.0 26.9 0.3 0.0 3.2 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.3 0.0 2.2 2.5 23.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 17.3 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 22.9 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 4.2 0.0 0.2 23.2 221.0 128.8 28.5 0.0 42.8 23.7 0.3 38.6 343.9 16.5 0.0 36.7 1.9 18.5 1.9 113.1 0.0 28.4 4.6 1.8 3.6 0.0 0.0 98.3 37.1 1.3 52.5 56.6 0.0 0.0 0.0 0.1 2.3 0.0 0.0 7.5 207.5 0.0 1.4 0.0 0.0 0.9 7.2 0.0 1.0 0.0 0.0 0.0 0.0 380.6 32.3 0.0 0.3 75.4 0.6 0.2 108.0 0.0 0.0 0.0 13.7 0.1 0.2 22.7 27.6 10.5 2.7 0.0 6.9 479.5 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Enhanced "Vesicles,Centriolar satellite" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Centriolar satellite" "CAB013097: AB_2533987, HPA051697: AB_2732569, HPA060686: AB_2684342" "unprognostic (4.15e-2)" "unprognostic (5.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (3.17e-2)" "unprognostic (7.12e-2)" "unprognostic (8.60e-2)" "unprognostic (4.83e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.29e-2)" "prognostic favorable (1.46e-5)" "unprognostic (9.93e-2)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" 140.0 231.6 79.7 123.9 86.4 126.0 150.1 83.4 105.0 159.3 78.5 223.8 139.8 117.4 130.9 480.0 146.1 185.1 156.3 86.1 97.4 162.9 124.1 148.1 141.2 87.0 83.0 104.9 107.6 192.5 106.8 214.4 101.3 150.3 224.2 99.0 195.1 126.2 119.6 288.5 158.9 149.2 87.2 183.9 216.2 201.8 86.0 143.6 155.3 109.6 246.0 269.8 232.2 86.7 285.2 330.3 330.1 240.8 294.7 275.0 431.1 297.0 300.4 264.4 313.0 305.8 497.4 370.7 295.8 342.6 262.3 429.0 525.0 393.2 248.2 243.7 314.9 445.3 219.9 274.1 224.7 211.5 254.0 282.8 438.1 260.2 214.7 281.7 595.2 197.8 364.5 214.3 378.1 283.7 209.9 167.3 275.9 1057.4 185.9 176.3 250.5 346.3 716.1 734.7 237.4 251.9 214.0 335.6 286.5 387.8 445.0 243.0 453.7 208.4 296.4 203.1 267.8 112.2 289.5 288.8 193.7 353.5 228.8 183.5 154.8 235.2 56.7 133.9 58.8 78.8 85.3 68.6 137.1 64.1 78.9 63.6 232.8 71.3 154.6 87.6 109.5 340.2 79.7 86.4 83.4 105.0 86.1 97.4 87.0 83.0 101.3 87.2 86.0 86.7 155.7 57.7 57.8 15.3 90.2 192.2 180.2 375.2 134.3 42.3 107.5 69.6 89.5 105.8 245.4 187.6 33.3 326.4 76.0 313.4 346.3 360.6 413.1 119.3 72.7 260.7 206.2 91.1 31.3 337.0 340.4 96.9 149.9 194.5 74.9 75.9 235.2 88.4 239.2 57.2 27.7 227.4 244.1 114.8 214.2 80.9 97.3 148.1 186.7 42.2 217.8 137.9 65.9 25.6 21.9 391.1 277.0 86.5 72.1 187.6 205.8 271.5 240.0 36.1 46.0 45.2 161.5 407.5 95.3 225.5 284.4 969.3 96.6 97.6 209.2 360.8 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RABGGTA PTAR3 ENSG00000100949 "Rab geranylgeranyltransferase subunit alpha" Q92696 14 24265538-24271611 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 59.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043488 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043488: AB_10794887" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (2.61e-3)" "unprognostic (1.13e-1)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (5.78e-2)" "unprognostic (3.89e-2)" "unprognostic (7.11e-2)" "unprognostic (3.12e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.51e-4)" "unprognostic (2.01e-1)" 11.3 14.7 6.9 7.7 7.0 10.0 11.3 7.6 9.4 14.7 6.1 12.2 11.0 9.3 10.0 59.2 12.1 9.2 16.3 7.5 8.5 13.7 14.8 13.9 9.8 8.3 7.7 10.6 17.7 16.9 15.2 7.8 8.2 12.2 8.5 3.1 20.1 8.3 19.1 19.9 13.1 6.9 7.4 17.1 16.3 11.8 7.9 9.0 11.9 12.5 12.4 10.0 19.4 8.1 10.6 13.0 6.8 10.6 8.9 17.4 31.9 15.2 12.8 21.4 19.4 12.2 17.4 13.1 11.8 16.3 9.5 20.4 7.0 33.2 9.2 20.8 14.4 8.6 11.0 45.9 17.9 18.8 36.3 19.9 35.9 11.4 13.5 11.6 19.7 16.4 9.0 16.1 16.3 41.0 12.5 10.1 2.3 14.0 19.2 9.3 6.2 14.5 20.5 15.6 16.9 9.7 10.5 29.9 12.8 9.4 12.5 13.7 14.5 11.2 7.8 6.1 10.5 17.2 13.9 8.7 9.5 11.5 17.6 11.9 25.7 17.1 16.0 46.8 13.3 16.3 15.3 12.4 32.0 10.4 12.8 10.0 7.3 16.9 33.1 5.4 18.1 18.4 6.9 7.0 7.6 9.4 7.5 8.5 8.3 7.7 8.2 7.4 7.9 8.1 9.3 9.6 11.6 4.6 18.0 17.7 19.6 61.6 35.9 7.7 13.8 14.0 12.4 15.7 28.1 5.5 6.2 38.0 14.4 25.0 15.6 23.4 3.3 9.7 5.8 9.3 13.1 7.8 5.1 27.1 31.1 10.1 23.4 11.9 36.2 8.3 9.7 7.1 26.5 11.8 4.3 14.5 26.4 17.9 10.4 7.7 9.0 18.3 16.0 3.7 18.8 9.0 12.3 4.0 3.7 39.3 23.7 7.2 20.3 15.4 27.7 20.4 15.5 5.3 6.6 5.8 12.0 3.3 34.2 36.9 12.4 57.3 16.8 10.3 18.0 20.9 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Basal prostatic cells: 11.3;Basal respiratory cells: 6.4;Prostatic glandular cells: 7.1;Squamous epithelial cells: 7.2;Suprabasal keratinocytes: 17.0;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 14.3" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.2 0.3 17.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.7 14.3 0.3 0.4 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 2.6 0.7 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 11.3 6.4 1.2 0.0 0.4 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 0.0 2.8 0.8 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.1 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.0 0.1 7.2 17.0 0.0 0.0 0.0 0.1 8.1 RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 51.2;Intestinal goblet cells: 58.0;Paneth cells: 54.5;Proximal enterocytes: 157.4;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.6;CACO-2: 27.5;MCF7: 11.5;SK-BR-3: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.99e-2)" "unprognostic (6.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-3)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.91e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.3 1.5 0.0 1.7 4.5 0.1 0.7 9.1 0.7 0.5 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.9 2.0 0.4 0.0 3.8 0.6 0.0 4.4 1.0 0.0 4.7 4.7 0.0 0.0 0.0 2.7 2.9 0.0 0.0 3.6 0.0 0.3 1.7 3.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 27.5 2.8 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 12.5 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.3 1.3 0.3 0.0 0.0 3.3 2.2 2.7 7.2 1.7 1.8 0.0 6.0 0.0 51.2 0.0 0.3 13.4 1.0 0.0 0.0 9.6 0.0 0.4 0.2 5.1 0.2 2.0 1.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 58.0 2.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 54.5 0.0 0.0 0.7 157.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.1 1.4 2.6 0.1 0.0 26.2 1.0 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 RHCG "C15orf6, PDRC2, RHGK, SLC42A3" ENSG00000140519 "Rh family C glycoprotein" Q9UBD6 15 89471398-89496589 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 4022.4;vagina: 1728.8" "Cell type enriched" "Detected in many" 21 "Squamous epithelial cells: 1544.7" "Cancer enhanced" "Detected in many" "cervical cancer: 152.9;head and neck cancer: 154.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.8;hTCEpi: 2.0;RT4: 1.2" "Region enriched" "Detected in many" 5 "olfactory bulb: 8.4" "Low region specificity" "Detected in some" "HPA041874, HPA043317" Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA041874: AB_2677719, HPA043317: AB_2678424" "unprognostic (1.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.52e-1)" "unprognostic (3.86e-3)" "unprognostic (1.98e-2)" "unprognostic (9.39e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (9.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.84e-2)" "unprognostic (2.55e-3)" "unprognostic (2.68e-1)" "unprognostic (2.80e-2)" "unprognostic (2.27e-1)" "unprognostic (9.45e-3)" 1.3 2.1 5.3 0.0 5.4 0.0 0.8 4.9 6.9 823.5 3.9 0.5 0.0 0.6 0.0 4022.4 0.7 0.7 1.4 5.1 4.9 117.4 3.4 0.3 0.0 4.8 4.9 0.8 3.2 0.0 4.3 0.0 4.8 3.4 0.0 2.5 593.6 0.8 1.0 14.6 0.9 0.3 5.1 0.6 3.5 1.3 5.0 0.8 0.5 0.0 461.7 3.7 1728.8 5.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.3 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.4 4.9 6.9 5.1 4.9 4.8 4.9 4.8 5.1 5.0 5.2 0.0 0.0 0.0 2.0 0.3 1.3 28.9 22.9 6.2 1.0 0.9 0.5 0.7 0.0 47.6 14.7 0.0 0.0 0.0 0.6 15.6 1.5 2.0 0.0 0.1 0.7 0.0 0.0 6.0 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 2.0 0.0 0.7 1.4 0.0 1.5 0.0 0.0 0.0 64.4 0.0 4.0 0.3 0.7 4.8 0.0 0.0 34.8 0.0 0.0 1.6 2.8 0.0 0.0 5.4 1.5 0.1 1544.7 17.8 0.0 0.3 0.0 0.2 70.5 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 72.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 52.3;Endometrial ciliated cells: 76.5;Gastric mucus-secreting cells: 61.2;Glandular and luminal cells: 174.2;Squamous epithelial cells: 71.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 32.2;GAMG: 41.2;HaCaT: 47.5;hTCEpi: 31.4;RPTEC TERT1: 28.3;RT4: 30.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA030942 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.6 0.0 0.1 0.4 0.0 0.6 4.3 0.0 0.1 11.8 3.7 3.1 9.7 1.1 2.4 72.2 5.8 5.2 1.5 0.1 0.1 11.5 19.1 4.2 0.1 0.3 0.6 0.1 14.3 7.4 10.8 2.3 0.1 10.7 2.0 0.6 14.8 9.8 0.0 21.5 13.6 0.1 0.1 0.0 15.5 2.0 0.1 7.8 7.9 0.0 5.2 6.3 22.3 0.1 14.3 9.0 0.0 0.0 0.0 0.0 13.7 0.1 0.1 0.2 0.2 23.5 32.2 0.0 13.3 2.9 41.2 47.5 0.7 19.2 0.0 0.0 9.4 0.0 6.9 8.8 0.0 0.0 0.0 0.0 31.4 0.2 4.2 0.0 0.0 14.3 0.0 0.0 0.0 10.3 2.0 0.0 0.8 9.3 26.1 0.0 0.0 2.3 28.3 30.8 4.5 0.3 15.5 15.7 15.1 1.3 9.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 4.2 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.1 0.1 0.1 28.9 9.1 0.0 0.1 15.8 27.4 24.0 52.3 0.0 13.0 12.4 1.1 17.2 28.0 3.7 0.0 8.3 0.3 22.8 9.8 12.4 1.5 76.5 16.9 0.9 22.7 0.0 0.0 10.4 5.1 0.6 61.2 174.2 2.5 0.0 0.0 17.0 1.0 0.0 0.0 14.2 16.2 0.6 1.4 1.6 0.0 0.9 7.2 0.0 0.0 0.4 0.0 0.0 0.0 19.0 11.8 0.0 0.0 24.0 26.5 13.5 22.2 0.9 0.0 0.0 1.3 1.4 2.5 71.2 15.2 2.5 1.5 0.0 11.2 24.1 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNF223 ENSG00000237330 "Ring finger protein 223" E7ERA6 1 1070967-1074306 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 10.6;esophagus: 26.2;vagina: 13.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 29.1;Endometrial ciliated cells: 30.9;Extravillous trophoblasts: 19.3;Gastric mucus-secreting cells: 38.2;Glandular and luminal cells: 32.1;Urothelial cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 11.1;HaCaT: 7.0;MCF7: 24.4;OE19: 7.0;SK-BR-3: 16.0;T-47d: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.71e-1)" "unprognostic (2.79e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.08e-5)" "unprognostic (3.50e-1)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (3.91e-1)" "unprognostic (5.09e-2)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.16e-1)" "unprognostic (4.06e-3)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (4.58e-1)" "unprognostic (9.52e-3)" 0.0 0.0 0.3 0.0 0.4 0.2 0.4 1.2 0.5 10.6 0.0 1.1 0.1 0.3 0.0 26.2 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.4 0.0 0.8 0.3 0.0 0.1 0.0 0.0 0.6 1.0 0.4 0.3 0.2 4.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 3.8 0.1 0.3 0.0 0.0 0.0 0.9 3.4 13.0 0.6 15.4 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.5 11.1 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 24.4 0.0 0.1 0.0 7.0 0.3 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.2 16.0 0.3 0.1 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.5 0.1 0.3 0.8 0.3 1.0 0.0 0.3 0.6 0.1 9.6 0.0 0.0 0.1 0.5 8.8 1.3 0.0 0.0 29.1 10.8 0.6 0.0 2.3 1.8 0.0 0.8 0.4 15.6 0.0 7.3 0.0 30.9 3.0 0.5 0.0 0.0 0.0 3.1 19.3 0.3 38.2 32.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 9.7 2.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.6 8.1 0.0 0.0 7.0 0.9 0.1 3.8 0.0 0.0 0.2 0.5 0.0 0.0 11.7 1.4 5.1 0.3 0.0 5.2 32.8 RPL22L1 ENSG00000163584 "Ribosomal protein L22 like 1" Q6P5R6 3 170864875-170870208 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 651.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 912.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048060, HPA056207, HPA068294" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA048060: AB_2732544, HPA056207: AB_2683065, HPA068294: AB_2732781" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.59e-1)" "unprognostic (1.45e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-3)" "unprognostic (1.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.17e-3)" "unprognostic (4.52e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (5.12e-2)" "unprognostic (3.55e-1)" "unprognostic (1.23e-1)" "unprognostic (6.96e-2)" 41.4 32.0 10.4 64.2 12.0 93.6 46.7 10.7 20.6 25.6 9.8 36.1 19.0 24.8 17.8 75.3 32.3 17.2 23.5 10.4 11.6 27.4 47.9 25.9 75.3 11.9 11.5 34.0 47.5 8.3 22.4 17.2 12.1 25.1 33.0 7.7 34.2 15.7 9.9 46.6 32.9 26.5 11.4 67.4 38.6 13.7 11.8 39.8 16.9 6.2 63.2 61.3 38.0 16.4 153.8 169.2 54.4 632.1 156.8 912.4 165.5 152.9 349.5 121.7 78.4 72.8 34.8 472.8 34.5 143.1 379.6 39.3 136.4 390.2 67.7 28.8 24.7 43.2 21.4 166.4 632.4 88.7 60.1 670.6 775.2 38.9 409.7 189.0 418.9 257.7 30.4 29.8 672.0 194.3 650.6 49.7 849.1 58.6 31.0 857.7 19.4 72.7 305.4 337.4 9.2 45.7 15.4 75.6 72.1 29.2 105.6 77.2 196.3 23.3 175.9 47.2 216.8 47.1 36.0 76.2 420.5 53.7 489.4 2.2 9.5 4.3 13.2 12.6 26.9 47.1 19.4 17.9 10.7 34.8 12.9 14.5 2.1 28.8 17.8 51.2 13.1 6.9 10.4 12.0 10.7 20.6 10.4 11.6 11.9 11.5 12.1 11.4 11.8 16.4 153.2 9.6 43.7 4.6 379.6 197.6 240.2 260.8 198.6 13.9 185.1 397.2 18.1 55.8 111.4 20.2 4.2 89.8 241.9 111.5 66.5 160.8 37.6 128.4 279.6 138.5 144.6 266.7 3.3 232.3 297.4 169.0 146.3 116.8 106.5 202.8 103.9 129.5 184.7 8.4 4.5 240.7 93.6 187.4 101.4 36.3 139.4 148.9 78.2 2.8 108.7 54.2 69.0 7.5 10.1 400.8 137.1 89.1 651.0 421.5 99.1 94.1 60.5 21.0 46.0 189.5 472.0 67.2 58.9 511.7 247.8 98.4 173.7 260.4 197.5 356.3 S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4751.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5473.4;Extravillous trophoblasts: 6093.0;Pancreatic endocrine cells: 6926.5;Urothelial cells: 6250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17820.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 7900000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: AB_2183487, HPA042745: AB_2678142" "unprognostic (1.85e-2)" "unprognostic (9.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (3.12e-2)" "unprognostic (7.61e-2)" "prognostic unfavorable (3.64e-5)" "unprognostic (3.34e-2)" "unprognostic (8.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.28e-3)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.24e-6)" "unprognostic (2.91e-1)" "unprognostic (2.75e-1)" "unprognostic (2.43e-3)" "unprognostic (8.86e-2)" 656.7 214.3 92.6 487.2 92.8 415.2 574.7 99.1 222.3 1070.5 106.8 303.0 181.6 297.7 675.4 4751.5 611.1 437.8 354.1 92.3 104.4 882.5 127.6 776.0 206.7 118.1 108.6 152.0 264.1 905.1 210.7 723.2 118.0 536.4 328.7 8.4 1247.1 544.1 91.0 894.7 239.5 468.3 110.2 713.7 482.6 68.9 124.1 303.5 325.3 150.9 959.9 1527.7 1771.1 126.8 1889.0 1483.7 70.5 542.1 1960.9 2451.3 1172.4 1796.3 2626.0 1439.7 1464.8 697.6 2066.0 2.5 1571.4 2355.4 1142.4 2595.4 73.7 3254.0 814.0 913.6 149.2 162.6 830.1 409.1 1511.3 149.6 1098.4 1867.2 3255.1 1577.8 1974.9 826.9 1116.1 0.3 340.9 352.1 2137.7 3058.8 19.8 694.0 513.9 4043.1 1491.9 2.5 757.1 1426.0 4361.1 3196.5 2.5 115.8 1367.7 1797.9 1255.3 1727.2 1378.9 1612.5 1584.8 757.0 533.1 1188.8 975.7 2.5 17.0 8.2 1713.0 490.9 915.2 7956.3 4682.6 7210.4 713.6 4560.1 939.4 354.9 1346.4 845.1 3020.5 252.7 391.5 437.0 17820.3 740.5 4871.8 1042.8 1269.9 5289.9 92.6 92.8 99.1 222.3 92.3 104.4 118.1 108.6 118.0 110.2 124.1 126.8 718.5 137.8 189.4 1.3 136.6 2210.3 3924.9 5473.4 1027.8 0.7 686.8 823.8 30.8 546.2 2673.9 2284.2 0.0 3257.0 384.0 421.7 1019.3 4344.5 277.6 1738.8 561.2 617.8 277.7 52.6 0.0 4330.2 6093.0 890.7 676.4 1503.0 437.6 251.1 372.6 11.6 3806.0 0.0 0.0 479.6 1485.2 1216.7 2054.0 634.0 320.9 1971.8 1243.3 15.9 2265.2 0.8 371.8 0.0 0.0 6926.5 690.2 258.4 153.8 4365.0 343.9 925.4 2674.2 2.4 210.4 536.2 1054.9 14.5 34.8 4207.9 2822.4 3753.1 470.4 334.8 500.2 6250.2 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 995.4;Pancreatic endocrine cells: 1307.3;Prostatic glandular cells: 1141.1;Squamous epithelial cells: 1028.7;Suprabasal keratinocytes: 908.8;Theca cells: 1528.4;Urothelial cells: 1522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1369.9;SK-BR-3: 1618.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" 166.8 79.1 81.3 61.9 79.8 0.8 159.7 78.6 98.0 333.0 70.8 139.7 121.5 78.4 19.8 2477.7 68.2 81.6 122.3 79.8 80.1 219.0 209.9 161.3 28.4 104.2 80.9 83.4 41.0 76.6 42.0 71.8 84.9 77.8 105.0 7.0 438.1 38.1 51.7 474.9 109.8 79.0 84.8 118.5 100.4 60.3 103.4 25.0 72.4 52.1 205.0 163.2 713.3 84.6 670.4 318.1 16.0 36.7 102.5 386.8 42.8 367.9 341.4 302.7 265.2 315.4 366.1 0.3 577.5 553.0 69.0 479.6 1.1 839.2 175.3 1.9 0.6 0.4 260.5 90.8 117.5 0.2 0.9 182.7 787.6 731.6 567.9 390.9 1369.9 0.0 8.5 0.8 677.3 918.7 0.9 1.4 69.0 1171.0 887.9 0.9 187.4 1.8 1150.3 236.1 0.8 1.9 267.6 1618.0 55.7 140.5 504.7 3.5 743.9 178.2 289.5 171.5 848.6 0.5 3.5 2.4 525.0 0.9 122.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 81.3 79.8 78.6 98.0 79.8 80.1 104.2 80.9 84.9 84.8 103.4 84.6 275.6 38.5 25.5 10.4 6.8 633.9 995.4 531.6 157.6 0.5 225.4 191.3 33.0 124.4 290.6 108.5 2.1 20.3 4.4 500.7 72.4 610.9 4.9 50.9 172.5 293.5 139.0 16.0 0.0 193.9 8.7 112.2 96.8 128.5 19.1 154.1 365.9 132.7 5.0 0.0 0.1 286.4 164.8 15.7 95.4 17.4 67.1 7.4 112.1 5.6 7.2 72.5 0.0 7.5 0.7 1307.3 610.0 61.3 5.6 1141.1 353.3 169.7 48.6 2.1 6.6 70.9 91.2 8.0 1.3 1028.7 908.8 8.2 12.9 1528.4 320.2 1522.5 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1065.7;lymphoid tissue: 1239.6;skin 1: 346.5;vagina: 1020.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 59.3;Club cells: 70.4;Ionocytes: 18.3;Suprabasal keratinocytes: 89.6;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.2;SK-BR-3: 16.9" "CAB001453, HPA006997, CAB033766" Enhanced Uncertain Cytosol "Secreted in other tissues" NA NA 14000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" 1.0 0.2 0.9 0.0 0.8 0.8 15.6 1.4 2.1 174.8 0.7 0.3 0.0 1.2 27.6 1065.7 0.3 0.2 0.5 0.8 0.8 0.1 0.5 0.4 0.2 0.9 0.8 0.5 0.4 0.0 0.2 0.2 0.8 0.5 0.0 0.0 55.5 0.2 0.4 346.5 0.2 1.4 0.8 0.3 0.4 0.3 0.7 12.4 0.2 0.0 1239.6 1.2 1020.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 7.2 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.7 16.9 0.0 0.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.4 2.1 0.8 0.8 0.9 0.8 0.8 0.8 0.7 1.1 0.0 0.0 0.0 0.0 0.0 11.7 0.2 59.3 0.0 0.0 1.1 0.0 0.0 0.0 70.4 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 1.9 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.3 0.0 0.0 0.0 4.7 0.2 0.2 3.8 89.6 26.4 0.1 8.4 0.6 0.4 S100A7A "S100A15, S100A7f, S100A7L1" ENSG00000184330 "S100 calcium binding protein A7A" Q86SG5 1 153416520-153423222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.6;lymphoid tissue: 5.9;skin 1: 1.6;vagina: 2.7" "Group enriched" "Detected in some" 8 "Early spermatids: 2.8;Late spermatids: 3.0;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in many" 4 "head and neck cancer: 25.6;melanoma: 12.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006997 Supported Uncertain Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA006997: AB_1079860" "unprognostic (2.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (4.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.7;Distal enterocytes: 104.6;NK-cells: 109.2;Paneth cells: 171.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 28.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 66.7;GAMG: 66.0" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA021318: AB_2183383, HPA021319: AB_1856554" "unprognostic (3.66e-2)" "unprognostic (5.35e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (8.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (4.76e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (8.31e-5)" "unprognostic (6.00e-2)" "prognostic unfavorable (8.40e-7)" "unprognostic (5.91e-2)" "unprognostic (1.37e-2)" "unprognostic (2.18e-2)" "unprognostic (3.64e-1)" 4.1 3.6 1.1 13.2 1.0 9.9 3.5 1.1 1.0 8.0 1.4 11.0 7.5 3.5 2.9 39.1 3.0 7.2 2.4 1.1 1.6 3.2 3.7 7.7 15.8 2.8 1.5 5.8 1.6 1.0 0.9 7.0 2.0 2.0 11.3 0.3 4.3 2.4 0.6 1.9 7.7 4.0 2.9 17.7 10.7 1.0 2.1 20.7 2.0 2.3 15.9 7.0 8.3 2.5 28.5 3.6 1.0 0.2 12.0 15.2 0.3 10.9 45.2 51.0 66.7 0.2 30.9 11.9 16.8 27.1 66.0 32.6 0.1 10.0 17.1 40.5 1.3 17.3 18.0 0.0 5.4 19.5 23.1 6.8 14.1 16.8 4.6 2.8 7.7 13.1 1.2 28.6 10.9 0.1 29.2 15.9 0.1 0.0 7.9 9.5 9.2 13.5 0.3 3.6 4.4 0.4 8.4 3.3 9.1 0.1 1.0 9.5 33.8 11.8 4.2 36.0 6.0 16.9 3.4 10.8 12.3 11.2 12.1 21.8 4.2 15.7 8.3 8.1 7.7 5.6 6.4 7.3 3.6 5.9 6.7 6.1 17.8 8.8 12.8 2.5 8.8 3.2 1.1 1.0 1.1 1.0 1.1 1.6 2.8 1.5 2.0 2.9 2.1 2.5 43.9 9.6 3.7 0.7 53.4 2.3 8.2 40.2 4.0 1.4 4.4 5.1 1.2 5.7 33.7 14.7 0.0 1.9 92.7 104.6 0.0 23.5 0.1 21.1 18.5 29.0 3.0 19.4 0.4 12.3 7.1 14.6 37.8 7.0 43.6 21.8 12.1 1.2 11.5 6.7 1.5 34.9 20.3 29.9 9.6 0.7 15.2 32.7 3.6 21.5 41.6 2.2 109.2 2.0 2.4 50.4 171.0 12.4 35.9 7.0 12.6 2.3 37.5 0.1 13.1 14.4 12.6 0.2 0.0 21.1 1.8 0.4 69.4 25.4 5.6 34.3 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SERPINB11 EPIPIN ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 27.4;prostate: 32.5" "Cell type enhanced" "Detected in some" "Club cells: 6.8;Prostatic glandular cells: 3.3;Respiratory ciliated cells: 4.4;Squamous epithelial cells: 13.7;Urothelial cells: 21.9" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (5.04e-3)" "unprognostic (4.76e-2)" "unprognostic (4.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 32.5 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 9.0 2.9 6.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.2 0.0 0.0 21.9 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SERPINB4 "LEUPIN, PI11, SCCA-2, SCCA1, SCCA2" ENSG00000206073 "Serpin family B member 4" P48594 18 63637259-63644256 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 78.6;esophagus: 93.3;vagina: 150.9" "Cell type enriched" "Detected in some" 4 "Basal respiratory cells: 3577.0" "Group enriched" "Detected in many" 5 "cervical cancer: 104.1;head and neck cancer: 29.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;HSkMC: 1.1;SiHa: 1.7;U-2197: 6.1" "HPA048341, HPA049988, HPA055992" Supported NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (8.81e-3)" "unprognostic (9.43e-2)" "unprognostic (8.96e-3)" "unprognostic (4.38e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (2.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.27e-2)" 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 78.6 0.0 0.0 0.0 0.6 0.0 93.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.0 23.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 4.5 21.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 3577.0 0.0 0.0 0.0 0.0 0.0 0.0 825.8 0.0 0.0 0.0 0.0 0.0 0.0 23.9 1.4 0.1 0.1 0.2 0.0 0.0 0.0 21.7 0.2 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 97.6 0.0 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 32.4 0.0 0.3 53.0 0.0 0.0 0.0 10.7 0.1 0.0 14.8 0.0 0.8 0.0 0.0 0.0 60.5 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967140-104029233 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 201.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 20.5 15.1 10.9 15.2 19.9 28.9 21.7 20.9 13.7 19.9 15.3 20.4 13.3 21.3 16.2 56.4 14.1 21.3 22.4 11.7 10.0 20.6 17.8 24.0 11.8 11.5 11.1 24.0 16.7 26.3 9.6 25.8 11.7 17.6 20.8 15.1 21.9 17.7 23.1 26.3 14.7 20.6 10.3 14.9 24.1 15.2 12.3 15.2 22.4 25.1 17.5 30.5 28.6 18.5 50.5 28.9 33.7 24.3 36.6 50.1 14.2 30.6 40.7 22.5 20.9 18.4 53.7 26.6 18.6 31.8 19.1 53.7 18.0 39.5 33.5 21.3 24.7 27.0 23.5 15.6 26.6 32.7 22.4 25.5 49.5 30.9 87.6 31.7 40.9 16.9 34.6 17.9 29.8 18.6 23.0 18.0 8.4 32.4 18.2 22.2 41.4 13.8 29.0 60.3 8.0 13.8 26.6 25.7 25.8 17.2 13.8 23.4 63.4 16.6 16.9 30.6 36.3 21.6 28.0 16.7 24.2 43.1 10.7 0.6 0.5 1.7 1.4 0.5 1.5 0.4 0.8 1.0 0.5 0.6 0.6 1.0 2.7 0.5 0.4 0.9 0.8 0.3 10.9 19.9 20.9 13.7 11.7 10.0 11.5 11.1 11.7 10.3 12.3 18.5 73.5 179.5 129.5 38.5 19.9 57.0 87.1 30.9 26.7 32.2 32.0 35.1 110.4 30.0 100.9 44.1 25.0 37.4 40.1 70.0 3.9 34.0 8.4 43.3 77.1 80.2 18.5 25.5 35.3 54.0 13.6 52.6 44.9 90.3 35.3 54.6 50.7 25.3 19.9 25.2 39.3 37.2 18.3 24.5 36.9 16.6 46.6 37.5 8.8 34.7 43.9 25.7 27.8 34.2 63.9 85.5 81.6 63.2 22.3 67.8 21.9 11.5 57.9 25.4 6.6 68.1 49.3 46.3 35.3 61.4 68.5 52.4 44.2 71.7 37.4 201.0 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SNX31 MGC39715 ENSG00000174226 "Sorting nexin 31" Q8N9S9 8 100572889-100663415 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 6.5;urinary bladder: 16.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 81.8" "Cancer enriched" "Detected in many" 22 "urothelial cancer: 24.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RT4: 80.7" "Region enriched" "Detected in single" 5 "thalamus: 2.6" "Not detected" "Not detected" "HPA024284, HPA053466" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024284: AB_1853894, HPA053466: AB_2682161" "unprognostic (1.39e-1)" "unprognostic (3.83e-2)" "unprognostic (7.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.20e-5)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "prognostic favorable (1.47e-4)" "unprognostic (2.54e-1)" "unprognostic (4.05e-2)" 0.6 0.1 1.0 0.0 1.2 0.2 0.4 0.8 3.1 0.4 0.6 0.3 0.0 0.3 0.2 6.5 0.3 1.1 1.7 1.0 1.1 0.2 0.5 0.1 0.4 0.0 0.0 0.4 0.3 0.3 0.2 0.0 0.0 1.4 0.1 0.2 1.2 0.2 0.6 0.6 0.1 0.5 0.4 0.1 0.7 4.0 0.7 0.3 0.5 0.5 3.6 16.4 1.7 1.5 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.0 0.0 0.0 80.7 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.0 1.2 0.8 3.1 1.0 1.1 0.0 0.0 0.0 0.4 0.7 1.5 0.5 0.0 0.0 6.2 0.1 0.4 3.3 0.2 9.6 0.0 0.2 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 81.8 0.2 0.1 0.4 0.0 0.0 12.8 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 19.7 0.6 0.2 0.0 1.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 1.2 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.3 3.7 0.3 0.5 9.7 0.4 0.0 0.1 0.0 0.0 6.0 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPRR1A ENSG00000169474 "Small proline rich protein 1A" P35321 1 152985231-152985500 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 8971.2" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 77.2;Club cells: 33.0;Squamous epithelial cells: 41.7;Suprabasal keratinocytes: 144.8" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 1736.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HaCaT: 23.8;hTCEpi: 68.6;RT4: 26.4" CAB011237 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB011237: " "unprognostic (1.39e-1)" "unprognostic (5.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.19e-2)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" 1.1 1.2 0.0 0.0 0.0 0.0 13.2 0.1 0.0 1261.6 0.0 0.7 0.0 1.0 0.0 8971.2 1.2 69.5 3.6 0.0 0.1 1.0 2.1 0.6 0.0 0.1 0.1 1.7 2.4 0.0 2.0 0.0 0.5 1.3 0.0 0.0 892.0 0.0 1.6 244.5 1.0 0.6 0.2 1.3 5.4 0.6 0.0 18.4 0.9 0.0 918.8 223.5 1935.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.8 0.0 0.0 0.0 23.8 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.0 26.4 0.4 0.0 2.2 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 0.1 77.2 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 3.8 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.0 41.7 144.8 0.0 0.1 0.0 0.0 17.1 SPRR1B "GADD33, SPRR1" ENSG00000169469 "Small proline rich protein 1B" P22528 1 153031203-153032900 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1386.5;esophagus: 2237.9;vagina: 1775.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 100.1;Club cells: 167.8;Pancreatic endocrine cells: 67.1;Suprabasal keratinocytes: 380.9;Urothelial cells: 94.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 1812.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "hTCEpi: 364.3" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.73e-1)" "unprognostic (2.39e-1)" "unprognostic (5.59e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (7.66e-5)" "unprognostic (2.22e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (7.64e-5)" "unprognostic (5.71e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.28e-4)" 0.9 0.6 0.0 0.0 0.0 0.3 6.9 0.0 0.0 1386.5 0.0 0.4 0.0 0.6 0.2 2237.9 0.7 16.9 1.0 0.0 0.0 0.5 1.3 0.5 0.0 0.0 0.0 0.8 1.4 0.0 0.9 0.1 0.0 0.6 0.0 0.0 735.5 0.0 1.4 542.0 0.6 0.5 0.0 0.5 1.6 0.4 0.0 7.5 0.6 0.0 447.7 10.7 1775.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.6 0.0 0.0 0.0 39.5 0.0 5.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 364.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.0 2.4 100.1 0.0 0.0 0.0 0.0 0.0 0.0 167.8 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 0.0 8.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 67.1 2.2 0.0 0.0 0.6 0.0 0.0 10.7 0.0 0.0 0.0 5.8 0.0 0.0 14.9 380.9 0.3 0.3 0.0 0.0 94.7 SPRR2A ENSG00000241794 "Small proline rich protein 2A" P35326 1 153056120-153057512 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 5262.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 37.6;Club cells: 23.0;Ductal cells: 20.6;Exocrine glandular cells: 57.1;Squamous epithelial cells: 82.3" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 743.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.4;hTCEpi: 7.8;hTERT-HME1: 10.3;Karpas-707: 12.6" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (3.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-3)" "unprognostic (1.64e-2)" "unprognostic (6.80e-3)" "unprognostic (3.51e-1)" "unprognostic (3.36e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.37e-5)" 1.6 0.9 0.0 0.0 0.0 0.1 0.9 0.0 0.1 1144.4 0.0 0.6 0.0 0.8 0.0 5262.1 0.8 7.8 1.7 0.0 0.0 1.4 1.8 0.6 0.0 0.0 0.0 1.6 2.1 0.0 1.2 0.0 0.0 0.6 0.0 0.0 1135.0 0.0 1.7 28.2 0.8 0.6 0.0 0.9 2.9 0.8 0.0 0.8 0.5 0.0 763.9 1.0 1226.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 7.8 0.0 10.3 0.0 0.0 0.0 0.8 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 2.5 0.3 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.5 0.1 37.6 0.6 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 57.1 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.6 0.0 0.0 82.3 11.8 0.0 0.0 0.4 0.0 2.1 SPRR2D ENSG00000163216 "Small proline rich protein 2D" P22532 1 153039732-153041931 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 2086.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 58.6;Club cells: 20.7;Squamous epithelial cells: 14.4;Suprabasal keratinocytes: 15.6" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 353.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTCEpi: 41.1;hTERT-HME1: 35.8;SK-MEL-30: 18.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.50e-2)" "unprognostic (1.84e-1)" "unprognostic (5.17e-2)" "unprognostic (5.14e-2)" "unprognostic (1.49e-3)" "unprognostic (3.58e-1)" "unprognostic (1.37e-3)" "unprognostic (6.85e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.62e-4)" 0.7 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 347.0 0.0 0.2 0.0 0.3 0.0 2086.0 0.3 0.5 0.8 0.0 0.0 0.4 0.6 0.3 0.0 0.0 0.0 0.6 0.7 0.0 0.4 0.0 0.0 0.2 0.0 0.0 313.0 0.0 0.8 185.7 0.3 0.3 0.0 0.2 1.0 0.3 0.1 2.7 0.2 0.0 383.2 0.4 473.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 41.1 0.0 35.8 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.2 0.2 0.0 0.0 1.2 0.0 0.8 0.0 0.0 1.1 0.1 0.3 6.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 58.6 0.0 0.0 0.0 0.0 0.1 0.0 20.7 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.2 0.0 0.0 14.4 15.6 0.3 0.0 0.1 0.0 0.8 SPRR2F ENSG00000244094 "Small proline rich protein 2F" Q96RM1 1 153112121-153113516 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 264.7;lymphoid tissue: 70.2;ovary: 112.5" "Cell type enriched" "Detected in some" 29 "Granulosa cells: 681.7" "Group enriched" "Detected in many" 5 "cervical cancer: 16.0;head and neck cancer: 53.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "K-562: 2.7" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-2)" "unprognostic (2.41e-2)" "unprognostic (4.37e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.96e-1)" "unprognostic (1.78e-3)" 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.8 0.0 0.0 0.0 0.1 0.0 264.7 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 112.5 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.1 0.0 0.1 70.2 0.1 29.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 18.8 0.0 0.0 0.0 681.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 10.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 23.0 0.0 0.7 0.0 0.0 0.0 0.2 4.5 0.0 0.3 SPRR3 ENSG00000163209 "Small proline rich protein 3" Q9UBC9 1 153001747-153003856 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 4257.2;esophagus: 19480.4;vagina: 6062.0" "Cell type enriched" "Detected in some" 11 "Squamous epithelial cells: 987.1" "Group enriched" "Detected in many" 4 "cervical cancer: 206.3;head and neck cancer: 423.4;stomach cancer: 113.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.5;CAPAN-2: 5.8;hTCEpi: 9.7;OE19: 4.4;RT4: 12.6;TIME: 3.4" "Not detected" "Not detected" HPA044467 Enhanced NA NA 5200 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA044467: AB_2678952" "unprognostic (2.78e-2)" "unprognostic (3.54e-1)" "unprognostic (8.77e-2)" "unprognostic (7.50e-3)" "unprognostic (9.67e-3)" "unprognostic (2.36e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.58e-2)" 4.0 3.5 0.0 0.1 0.0 0.0 3.0 0.0 0.0 4257.2 0.0 2.6 0.1 3.5 0.0 19480.4 3.4 38.1 7.4 0.0 0.0 2.6 5.8 1.7 0.0 0.0 0.0 4.4 8.8 0.0 11.0 0.7 0.0 3.4 0.1 0.0 3157.9 0.0 5.0 7.5 4.2 1.7 0.0 3.4 15.2 2.1 0.0 1.4 2.3 0.0 2399.3 65.1 6062.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 3.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.0 0.0 1.1 0.0 0.0 12.6 0.0 0.0 0.3 2.7 0.0 0.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.0 7.4 0.0 0.0 0.0 0.1 0.0 41.3 0.0 0.0 5.9 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.2 1.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.4 0.0 0.1 2.1 0.0 0.0 0.0 1.0 0.0 0.0 987.1 0.0 7.5 0.4 0.1 0.0 89.6 SRSF9 "SFRS9, SRp30c" ENSG00000111786 "Serine and arginine rich splicing factor 9" Q13242 12 120461672-120469748 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049849 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Nucleoli "HPA049849: AB_2680911" "unprognostic (3.80e-1)" "unprognostic (3.84e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-2)" "unprognostic (2.41e-1)" "unprognostic (2.50e-3)" "prognostic unfavorable (9.85e-7)" "unprognostic (9.65e-3)" "prognostic unfavorable (7.80e-4)" "unprognostic (2.31e-2)" "unprognostic (4.35e-1)" "unprognostic (1.19e-2)" "unprognostic (1.19e-3)" "unprognostic (9.57e-2)" "unprognostic (3.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.60e-1)" 68.2 112.1 71.2 75.5 74.3 95.0 72.0 73.9 75.2 70.3 81.0 88.7 73.0 57.5 85.5 126.6 76.1 48.7 38.8 70.6 75.1 94.7 92.0 62.1 99.3 72.7 77.2 71.2 113.8 94.2 78.2 85.2 74.0 76.9 84.2 21.8 77.1 57.4 30.0 80.6 63.5 58.9 74.4 86.7 82.6 93.3 77.6 110.2 80.6 27.5 129.1 82.9 75.6 72.1 334.7 229.2 344.3 222.7 153.6 153.7 365.3 224.3 200.7 281.5 240.2 276.9 153.1 323.6 254.7 189.4 152.7 194.9 312.0 318.9 308.5 244.7 321.9 276.3 152.8 273.5 197.7 344.7 241.8 163.4 201.8 244.6 211.0 301.2 260.4 207.0 353.6 95.3 245.9 466.8 339.7 668.7 429.6 224.8 198.2 374.2 144.1 312.9 246.4 420.4 303.9 217.3 262.5 137.3 276.2 222.4 415.9 299.4 229.1 207.8 247.0 157.8 246.3 288.6 234.5 404.9 218.8 255.7 221.5 28.7 16.9 49.3 22.5 19.8 17.5 41.2 17.4 19.9 22.5 36.7 17.3 19.1 19.7 26.5 27.7 30.7 20.1 8.7 71.2 74.3 73.9 75.2 70.6 75.1 72.7 77.2 74.0 74.4 77.6 72.1 172.6 25.6 37.2 17.3 190.1 264.9 269.7 81.2 140.0 74.5 235.6 174.4 1.7 157.3 60.4 161.8 29.2 339.2 204.5 119.5 489.1 200.6 68.5 179.1 149.9 143.8 144.7 141.9 24.1 155.1 469.4 148.9 105.5 143.9 33.7 321.3 132.8 150.0 202.9 72.3 23.6 160.5 63.1 136.3 322.0 28.5 124.5 171.3 200.9 11.2 192.7 134.4 129.8 14.1 24.1 152.4 102.2 155.0 317.8 336.8 89.8 404.3 63.6 55.3 52.6 128.1 165.5 288.5 248.8 218.2 313.4 475.4 158.1 433.1 160.6 392.2 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 TGM3 TGE ENSG00000125780 "Transglutaminase 3" Q08188 20 2296001-2341079 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "esophagus: 1838.1" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 46.2;Squamous epithelial cells: 22.5" "Cancer enriched" "Detected in many" 9 "head and neck cancer: 81.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 295 "neutrophil: 30.3" "Lineage enriched" "Detected in single" 303 "granulocytes: 30.3" "Cell line enriched" "Detected in single" 14 "EFO-21: 5.2" HPA004728 Approved NA NA 14000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004728: AB_1080360" "unprognostic (7.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.18e-2)" "unprognostic (3.23e-3)" "unprognostic (4.27e-2)" "unprognostic (4.20e-2)" "unprognostic (8.62e-2)" "unprognostic (4.21e-2)" "unprognostic (1.50e-1)" "unprognostic (8.00e-2)" "unprognostic (4.88e-3)" "unprognostic (1.35e-1)" "unprognostic (7.78e-8)" "unprognostic (1.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (9.67e-2)" 0.6 0.3 0.2 0.2 0.0 1.4 3.9 0.0 0.1 54.3 0.0 0.3 0.0 0.2 0.8 1838.1 1.4 2.2 0.4 0.2 0.0 0.2 0.8 0.5 0.0 0.1 0.3 0.3 1.1 0.0 1.6 0.1 0.1 0.6 0.8 0.0 229.3 0.0 0.4 83.1 0.4 0.0 0.1 0.4 2.2 2.0 0.0 0.1 0.1 0.0 142.9 0.3 31.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 1.9 4.0 0.1 0.1 46.2 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.2 3.7 0.0 0.0 0.3 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.2 0.0 0.0 0.0 0.1 1.2 0.5 22.5 8.2 0.0 0.0 0.1 0.3 0.2 THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex 3" Q96J01 5 175917873-176034680 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 132.1;Early spermatids: 187.0;Squamous epithelial cells: 226.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Enhanced Nucleoplasm,Vesicles No No "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm Vesicles "HPA042764: AB_10965055, HPA044009: AB_10959603, HPA045071: AB_10959461" "unprognostic (1.13e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-3)" "unprognostic (6.48e-3)" "unprognostic (8.60e-2)" "unprognostic (3.57e-2)" "unprognostic (3.06e-3)" "unprognostic (2.02e-2)" "unprognostic (3.41e-2)" "unprognostic (1.11e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-2)" "unprognostic (8.80e-3)" "unprognostic (3.20e-1)" "unprognostic (2.86e-1)" "unprognostic (3.16e-2)" "unprognostic (2.91e-1)" 12.0 14.5 22.0 11.4 15.9 35.1 21.4 23.0 40.6 23.1 19.1 27.0 12.5 13.4 63.2 82.9 15.1 8.0 9.3 40.2 14.9 16.3 22.2 11.9 29.1 15.5 13.3 18.8 15.3 10.0 15.9 17.4 15.9 14.6 21.1 12.1 22.5 14.9 12.6 26.5 16.2 12.2 13.2 17.7 17.5 51.3 15.4 39.2 20.5 17.6 45.5 17.4 33.5 15.9 82.1 44.7 47.0 102.7 44.1 39.3 168.0 48.4 44.6 104.5 120.4 63.5 65.2 105.6 68.3 27.9 112.6 69.2 71.6 206.0 109.7 73.5 103.3 57.3 46.2 70.7 14.6 94.6 49.2 33.3 85.9 90.0 45.2 23.3 58.3 98.0 88.1 46.5 66.9 98.7 64.0 57.9 40.1 82.3 160.3 110.7 59.3 110.4 75.2 60.7 89.5 51.4 100.0 48.5 52.5 67.4 55.3 86.1 45.1 35.9 40.8 55.6 88.2 23.2 44.1 64.4 26.7 90.1 28.5 16.5 26.9 15.1 39.3 33.5 48.4 49.6 81.7 48.9 43.1 70.6 99.7 62.4 3.9 42.3 31.5 39.8 133.6 59.1 22.0 15.9 23.0 40.6 40.2 14.9 15.5 13.3 15.9 13.2 15.4 15.9 14.9 12.8 8.6 2.0 35.8 44.5 34.1 64.5 132.1 12.3 17.7 18.0 4.0 10.0 24.4 25.8 10.4 40.8 25.1 8.1 41.1 25.1 187.0 50.2 18.4 16.1 16.8 63.9 5.2 19.2 84.3 15.2 26.5 44.9 12.0 18.8 13.9 20.3 24.6 6.7 3.7 16.3 26.4 13.2 14.9 122.0 14.6 14.3 8.8 1.9 15.4 8.9 27.8 4.5 2.0 21.9 11.6 19.2 55.9 18.4 10.4 46.8 15.8 12.0 19.7 10.6 22.8 107.9 48.3 226.5 40.9 20.0 33.3 25.0 27.7 31.1 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 94.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 65.9;Intestinal goblet cells: 40.4;Paneth cells: 41.7;Proximal enterocytes: 60.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 34.2;RT4: 37.9;SCLC-21H: 40.8;SK-BR-3: 58.4;T-47d: 53.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" 0.4 0.3 0.1 1.4 0.1 0.7 3.0 0.1 1.0 20.6 0.2 12.1 24.4 1.1 0.3 94.6 7.0 3.6 0.4 0.0 0.2 6.2 24.4 2.2 0.2 0.2 0.0 0.2 22.9 5.2 11.4 1.7 0.1 11.3 6.6 0.1 22.5 4.5 4.9 37.0 23.6 0.3 0.0 0.1 12.6 3.7 0.2 0.6 0.6 0.6 4.3 12.8 41.0 0.1 23.7 15.0 0.1 0.0 0.0 0.1 5.0 0.8 0.3 0.9 0.1 20.9 25.4 0.5 7.6 0.3 7.5 17.0 0.0 9.7 0.3 0.2 0.9 0.1 15.3 9.7 0.2 0.0 0.0 0.0 8.9 0.3 8.0 0.4 0.1 6.3 0.2 0.1 0.0 34.2 0.2 0.1 0.7 13.5 19.3 0.5 0.0 10.9 7.3 37.9 40.8 0.1 6.4 58.4 0.1 0.5 53.7 0.1 0.0 0.0 8.2 9.7 1.1 0.1 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.1 2.9 3.2 4.4 0.0 1.6 4.0 5.8 7.2 2.2 1.1 12.1 5.5 7.5 11.5 18.2 9.2 0.0 7.1 1.4 65.9 1.9 13.2 0.0 19.3 3.4 1.4 7.2 0.0 0.3 11.0 8.7 1.7 23.4 31.7 1.3 0.5 0.0 14.2 0.8 0.0 0.1 40.4 14.2 0.6 2.6 0.0 0.0 1.4 0.0 0.0 0.6 0.5 0.0 0.0 0.0 13.1 41.7 0.0 4.6 10.4 60.5 5.1 28.0 0.6 0.0 1.8 3.0 0.0 0.1 15.4 9.2 16.8 1.2 0.1 19.4 16.0 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" 12.2 7.4 4.8 13.6 4.9 9.7 9.4 4.2 5.3 11.4 6.7 15.4 15.5 9.9 10.3 43.4 13.2 11.8 6.9 4.2 3.7 13.5 13.7 21.7 12.8 5.0 5.2 6.9 8.0 7.3 3.4 21.9 4.9 7.5 15.4 3.6 12.8 9.8 3.4 15.0 16.0 9.6 4.9 13.7 16.9 3.4 5.8 12.6 9.6 6.4 19.5 16.4 18.7 5.0 59.4 56.0 22.3 5.8 21.6 35.9 25.8 26.1 35.5 26.7 23.8 21.8 42.4 13.9 21.7 28.0 18.9 82.3 20.7 58.5 33.9 23.8 9.1 20.6 62.6 17.9 24.0 26.6 22.1 24.2 55.7 21.5 66.2 32.9 47.7 20.0 22.3 20.6 32.6 43.9 17.8 17.7 12.4 36.3 10.3 21.0 26.7 37.8 43.5 41.5 5.4 14.6 43.5 28.9 15.6 29.7 19.7 21.0 53.8 33.9 22.6 27.8 31.3 12.5 39.5 15.6 21.7 48.0 20.4 47.6 27.9 41.4 22.7 34.7 20.2 20.4 19.8 20.3 20.6 23.8 16.7 15.7 45.5 18.8 39.3 29.0 26.0 16.7 4.8 4.9 4.2 5.3 4.2 3.7 5.0 5.2 4.9 4.9 5.8 5.0 147.9 397.4 68.2 23.8 43.5 106.9 91.4 66.3 70.6 8.3 38.8 27.3 45.8 30.0 112.7 42.3 14.6 56.1 63.3 117.4 41.1 85.8 38.9 67.5 87.6 131.6 18.6 50.9 29.4 71.6 66.3 84.1 71.9 91.3 143.0 28.8 101.4 52.9 53.9 15.2 25.5 52.0 36.7 51.7 74.1 99.3 45.1 88.4 32.0 33.7 67.5 19.2 60.8 17.1 17.1 152.6 79.0 44.4 44.1 160.3 65.5 56.5 82.2 12.6 13.1 35.2 58.0 14.5 13.9 137.0 132.1 51.3 74.3 57.4 59.9 215.9 TMPRSS11A "ECRG1, HATL1, HESP" ENSG00000187054 "Transmembrane serine protease 11A" Q6ZMR5 4 67909395-67964140 "Enzymes, Predicted membrane proteins, Transporters" "Cell cycle" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 86.1;lymphoid tissue: 28.4;vagina: 41.7" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 50.7" "Group enriched" "Detected in some" 9 "cervical cancer: 14.4;head and neck cancer: 11.6;lung cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078316 Enhanced NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA078316: " "unprognostic (1.63e-1)" "unprognostic (4.60e-2)" "unprognostic (1.76e-2)" "unprognostic (6.98e-2)" "unprognostic (1.98e-1)" "unprognostic (2.66e-1)" "unprognostic (4.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (3.50e-1)" "unprognostic (2.33e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 19.9 0.0 0.0 0.0 0.0 0.0 86.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.4 12.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.0 28.4 0.3 41.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.3 0.2 0.3 0.9 0.4 1.1 0.1 0.3 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.5 1.2 0.6 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.1 0.2 50.7 0.0 0.0 0.0 0.0 0.0 7.2 TMPRSS11B HATL5 ENSG00000185873 "Transmembrane serine protease 11B" Q86T26 4 68226653-68245694 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 390.7;lymphoid tissue: 82.2;vagina: 118.3" "Group enriched" "Detected in some" 22 "Early spermatids: 10.4;Late spermatids: 14.5;Squamous epithelial cells: 8.2" "Group enriched" "Detected in some" 12 "cervical cancer: 2.6;head and neck cancer: 2.6;stomach cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (4.24e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.92e-1)" "unprognostic (3.96e-1)" 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.2 56.8 0.1 0.0 0.0 0.0 0.0 390.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 58.6 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.2 0.0 0.0 0.0 82.2 0.0 118.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 8.2 0.0 0.0 0.1 0.0 0.0 0.2 TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "cervix: 51.6;esophagus: 71.8;lymphoid tissue: 34.4;salivary gland: 21.0;vagina: 76.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 24.4;Club cells: 13.8;Inhibitory neurons: 3.9;Oligodendrocyte precursor cells: 5.0;Urothelial cells: 12.0" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA077704: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.3 2.6 51.6 1.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 2.6 2.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 21.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.9 0.2 0.0 0.0 34.4 0.6 76.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 2.6 1.1 1.1 2.6 2.0 2.7 0.7 0.9 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.1 24.4 0.6 0.0 0.0 0.0 0.3 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 5.0 1.5 0.5 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 12.0 TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 89.5;esophagus: 220.2;salivary gland: 56.7;vagina: 156.3" "Cell type enriched" "Detected in some" 14 "Ionocytes: 476.0" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;OE19: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Enhanced Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA043816: , HPA051062: AB_2681329" "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 89.5 0.0 0.0 0.0 0.0 18.2 220.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 2.2 0.0 0.0 56.7 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 24.5 6.5 156.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 12.9 0.7 0.0 0.0 0.5 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.3 6.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 476.0 0.0 0.3 1.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.2 6.6 0.3 1.1 0.7 0.0 0.0 32.6 TP53AIP1 p53AIP1 ENSG00000120471 "Tumor protein p53 regulated apoptosis inducing protein 1" Q9HCN2 11 128934731-128943399 "Predicted intracellular proteins" Apoptosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;lymphoid tissue: 29.5;skin 1: 20.4;vagina: 13.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 45.5;Basal respiratory cells: 42.4;Basal squamous epithelial cells: 179.2;Endometrial ciliated cells: 38.7;Respiratory ciliated cells: 27.3;Squamous epithelial cells: 72.1;Suprabasal keratinocytes: 32.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044300, HPA048797" Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA044300: AB_2678888, HPA048797: AB_2680524" "unprognostic (4.12e-7)" "unprognostic (3.00e-2)" "unprognostic (1.48e-1)" "unprognostic (1.64e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-2)" "unprognostic (1.18e-1)" "unprognostic (4.66e-2)" "unprognostic (1.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.94e-1)" "unprognostic (6.57e-6)" "unprognostic (1.10e-2)" "unprognostic (3.71e-1)" "unprognostic (7.75e-2)" "unprognostic (1.78e-2)" 0.0 0.6 0.9 0.0 0.8 0.0 1.3 1.1 1.3 5.6 0.6 0.1 0.0 0.1 2.5 24.5 2.7 0.0 0.0 0.8 0.6 0.8 0.1 0.2 0.0 1.0 1.0 0.0 0.2 0.0 1.8 0.0 0.9 2.0 0.0 0.5 3.9 0.8 0.1 20.4 0.1 0.0 0.5 0.0 0.0 1.6 1.0 29.5 0.0 0.0 1.1 0.0 13.6 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.1 1.3 0.8 0.6 1.0 1.0 0.9 0.5 1.0 0.8 0.2 0.0 0.5 1.0 0.0 45.5 11.4 42.4 179.2 0.7 1.5 23.9 0.3 0.0 5.3 0.0 0.0 0.1 0.0 0.3 7.9 0.0 0.9 38.7 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 1.8 1.1 0.0 0.4 1.8 1.0 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 27.3 0.4 0.0 0.6 1.6 0.2 0.3 72.1 32.7 0.3 0.3 0.0 0.3 2.6 TRAFD1 FLN29 ENSG00000135148 "TRAF-type zinc finger domain containing 1" O14545 12 112125538-112153604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 117.6;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039254, HPA039266" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA039254: AB_10805358, HPA039266: AB_10795142" "unprognostic (7.80e-2)" "prognostic favorable (5.73e-4)" "unprognostic (6.12e-2)" "unprognostic (1.44e-1)" "unprognostic (9.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (9.26e-6)" "unprognostic (1.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.33e-3)" "prognostic favorable (3.92e-5)" 17.1 14.6 15.9 30.4 21.5 30.1 20.3 21.2 18.9 21.2 24.7 40.6 16.7 16.8 15.6 32.0 15.4 17.7 22.3 15.1 17.3 15.7 13.5 26.3 37.1 22.4 20.0 18.7 11.8 15.7 11.7 19.0 23.0 22.0 20.6 18.7 19.0 19.8 12.9 35.9 20.3 25.9 20.5 31.3 17.2 29.1 20.1 32.6 13.8 11.4 40.4 29.9 21.7 30.2 23.8 26.2 41.8 40.8 28.8 27.3 22.1 27.2 38.8 36.5 29.4 29.5 21.9 27.4 22.6 28.9 15.7 49.0 42.0 26.3 24.2 47.3 40.1 44.4 37.7 16.3 50.0 27.1 67.7 34.4 43.5 27.1 35.7 37.2 32.6 16.6 50.1 16.9 23.6 41.2 31.5 39.0 35.4 27.8 31.8 43.8 25.6 46.8 24.3 89.5 36.4 27.3 57.4 55.7 15.1 30.8 35.8 38.7 22.1 17.2 12.2 17.1 14.3 40.3 36.2 29.3 18.5 21.6 19.1 323.7 96.1 226.1 45.1 86.8 30.1 56.7 43.1 40.3 50.1 60.2 39.4 36.6 188.2 70.8 93.1 33.5 63.7 101.2 15.9 21.5 21.2 18.9 15.1 17.3 22.4 20.0 23.0 20.5 20.1 30.2 10.7 19.2 13.1 6.8 12.4 12.2 7.4 18.5 30.7 7.0 14.7 11.8 10.9 5.7 18.9 12.9 25.0 20.1 8.5 15.4 5.9 21.3 1.7 9.0 14.3 11.3 15.6 9.0 8.4 20.8 15.6 15.1 15.3 7.5 12.0 10.0 7.9 5.7 14.8 15.2 12.2 10.3 30.5 11.9 9.9 3.7 11.8 14.0 7.2 7.5 117.6 9.9 19.6 10.6 28.6 25.8 15.5 12.8 8.7 22.7 13.0 6.3 10.2 10.9 0.0 5.6 8.8 75.6 36.0 22.0 15.2 26.4 14.0 10.0 9.4 14.4 TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 153.4;Squamous epithelial cells: 95.5;Urothelial cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Cell line enhanced" "Detected in all" "A549: 283.8;HaCaT: 229.0;HeLa: 203.8;OE19: 364.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" 18.3 32.7 14.1 7.8 16.2 17.4 13.4 17.7 21.5 44.9 10.3 14.1 22.8 6.1 4.9 145.9 8.8 16.3 23.1 13.5 15.8 8.5 5.9 14.5 9.7 16.9 16.0 7.3 6.0 3.6 4.4 34.5 17.2 10.2 11.2 3.6 38.0 11.7 28.1 44.9 12.5 9.0 15.8 6.0 31.7 12.7 17.2 10.1 18.7 27.2 37.3 35.7 70.2 22.1 91.5 283.8 8.6 19.4 40.4 46.1 9.6 14.8 51.9 17.9 25.0 17.2 115.6 9.8 54.7 64.7 106.9 229.0 25.6 65.7 12.0 120.0 16.4 4.5 203.8 9.5 67.1 5.4 9.6 25.7 40.9 39.3 22.3 49.6 38.8 11.4 5.7 45.8 49.2 32.2 20.2 11.7 13.1 364.2 17.0 8.7 71.8 6.9 92.4 116.0 6.4 17.7 64.7 72.2 22.1 49.7 10.9 12.6 61.0 22.5 26.3 10.9 51.3 11.1 12.9 1.0 34.6 12.6 58.3 0.4 3.8 1.0 1.2 1.1 0.8 0.5 4.9 1.5 2.6 0.6 1.3 2.6 0.6 0.9 0.5 0.4 45.1 2.3 14.1 16.2 17.7 21.5 13.5 15.8 16.9 16.0 17.2 15.8 17.2 22.1 34.9 38.5 2.6 14.0 5.3 30.8 59.0 55.6 10.2 7.2 11.8 5.7 12.5 10.0 73.5 11.0 18.8 13.6 2.8 9.9 0.0 49.1 1.1 16.5 9.9 28.7 4.2 9.0 9.6 17.3 8.4 9.6 34.7 25.7 4.5 12.4 3.6 3.2 4.0 3.3 14.0 21.7 28.5 2.9 8.6 3.9 7.2 2.9 7.2 11.2 13.0 6.6 4.1 18.6 19.2 153.4 26.9 4.5 3.7 29.5 4.3 6.2 33.5 8.4 6.6 5.8 14.0 10.3 12.1 95.5 77.6 4.7 5.9 60.9 18.4 111.9 TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.6;vagina: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.4;Gastric mucus-secreting cells: 23.0;Intestinal goblet cells: 27.1;Paneth cells: 36.9;Proximal enterocytes: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 9.0;CAPAN-2: 10.7;HaCaT: 12.3;hTCEpi: 6.9;OE19: 14.7;RPMI-8226: 8.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035072 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" 0.4 0.9 1.0 2.4 3.2 1.4 2.6 0.7 1.9 21.7 2.6 14.5 15.7 1.5 2.7 109.6 3.4 2.7 0.2 1.0 2.4 9.3 6.1 2.1 1.6 0.7 0.7 0.4 9.4 16.5 6.1 0.2 0.7 6.3 11.2 0.2 17.5 1.7 0.6 25.0 17.4 0.7 0.5 2.0 13.1 0.7 2.2 2.3 4.1 0.0 7.2 3.7 48.1 0.7 9.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 10.7 0.1 0.4 0.0 0.0 12.3 0.0 3.6 0.0 4.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.1 14.7 1.1 0.1 0.1 8.1 0.5 2.2 0.3 0.2 0.7 0.1 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.1 0.8 2.2 0.1 0.1 0.1 0.0 1.0 0.0 2.5 3.4 0.0 2.0 0.7 1.6 3.7 0.0 0.5 1.4 1.7 1.3 1.6 0.0 0.0 2.7 0.5 1.0 3.2 0.7 1.9 1.0 2.4 0.7 0.7 0.7 0.5 2.2 0.7 0.0 0.0 3.1 0.0 1.8 1.3 5.9 3.2 3.4 0.0 3.9 3.6 2.7 15.7 4.5 3.7 0.0 0.3 5.9 72.4 7.9 5.0 2.7 3.3 0.4 0.3 2.4 2.7 0.3 9.1 0.4 0.5 23.0 3.2 0.0 0.0 0.4 2.2 0.0 0.0 0.1 27.1 4.1 0.0 0.3 1.1 0.3 0.4 1.8 0.0 0.0 0.0 7.2 0.0 0.1 10.5 36.9 0.0 1.0 6.0 51.7 8.9 5.7 0.0 0.0 0.0 0.4 0.4 0.9 19.7 4.5 0.0 4.1 0.1 15.4 13.9 TTC9 "KIAA0227, TTC9A" ENSG00000133985 "Tetratricopeptide repeat domain 9" Q92623 14 70641916-70675366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.1" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 36.0;Respiratory ciliated cells: 38.1;Urothelial cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 18.2;Daudi: 15.9;RH-30: 21.3;SK-BR-3: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079473 Approved "Nuclear bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies" "HPA079473: " "unprognostic (2.37e-2)" "unprognostic (6.01e-2)" "unprognostic (9.29e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.81e-2)" "unprognostic (2.38e-2)" "unprognostic (2.53e-2)" "unprognostic (7.12e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.18e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.10e-8)" "unprognostic (1.22e-2)" "unprognostic (1.01e-1)" "unprognostic (3.16e-2)" "unprognostic (9.38e-2)" 1.4 1.2 6.4 4.0 6.8 0.9 3.7 3.3 9.8 5.4 1.5 0.8 0.8 1.2 1.4 60.1 10.2 3.4 2.1 6.4 5.9 2.9 1.1 4.4 9.3 5.7 3.9 0.1 1.5 2.9 3.7 4.0 5.5 2.5 0.8 6.0 12.6 1.6 9.5 5.9 2.5 0.8 3.7 5.7 4.1 0.5 4.3 5.1 4.0 5.2 15.4 4.4 13.7 6.5 18.2 2.1 6.7 0.3 0.0 0.0 7.1 0.3 0.1 0.5 2.2 0.4 8.9 15.9 2.4 0.1 1.5 6.6 5.0 0.6 0.3 0.5 1.9 2.2 0.7 5.2 0.0 0.0 4.4 0.6 1.2 0.0 0.1 0.3 0.0 3.5 0.0 1.4 7.3 9.0 0.4 0.2 3.7 13.0 2.3 3.7 21.3 0.1 11.0 4.1 4.1 2.0 2.0 36.4 0.0 4.0 12.7 0.6 0.0 0.0 3.2 0.0 0.3 0.0 0.2 4.9 0.0 0.4 0.1 0.0 0.0 0.6 0.4 0.3 0.9 0.6 0.7 0.5 0.0 1.2 1.1 0.7 0.8 0.0 1.5 0.0 0.4 0.2 6.4 6.8 3.3 9.8 6.4 5.9 5.7 3.9 5.5 3.7 4.3 6.5 3.8 3.2 7.2 1.3 11.3 1.0 4.7 16.3 1.2 3.8 13.7 10.5 1.8 14.3 24.8 9.2 6.2 24.1 1.5 0.2 1.9 21.0 0.4 8.3 2.3 5.9 1.2 0.0 10.5 5.8 2.5 1.2 4.1 19.1 1.3 15.2 0.4 2.2 2.8 0.0 13.6 0.5 16.2 4.1 0.8 0.7 0.0 2.1 7.2 3.7 3.0 15.8 4.1 9.0 0.7 36.0 0.5 0.0 4.4 13.0 0.0 0.3 38.1 5.4 0.0 0.7 2.1 0.1 2.6 9.0 1.7 7.4 7.6 0.2 0.5 56.9 TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 479.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 98.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 4114.3" "Low region specificity" "Detected in all" "HPA039247, HPA043684, HPA063394" Supported Supported Microtubules NA Yes 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-2)" "prognostic favorable (7.37e-5)" "unprognostic (3.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.88e-2)" "prognostic unfavorable (8.48e-8)" "prognostic unfavorable (6.85e-4)" "unprognostic (2.11e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (5.64e-6)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.26e-7)" "unprognostic (2.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (5.45e-3)" 92.6 57.8 12.4 110.5 12.1 148.8 54.7 13.9 18.0 101.0 41.9 158.2 106.9 59.6 62.7 479.4 50.8 92.1 55.3 12.8 16.4 113.5 69.3 74.1 78.6 15.7 14.1 38.3 52.6 22.5 28.0 109.9 15.5 43.7 156.5 2.5 139.0 46.4 45.3 166.1 117.6 129.8 15.7 42.1 115.2 26.3 22.6 103.3 56.3 42.5 170.7 222.5 168.8 15.4 1295.3 987.5 211.7 363.9 220.5 368.4 816.3 1010.1 1126.1 1742.1 927.3 966.9 947.0 578.9 1053.2 1194.2 1047.3 580.5 1246.0 1412.1 1150.2 564.1 449.7 703.4 406.7 943.7 165.2 550.9 498.4 269.8 663.0 1485.6 619.9 550.6 1139.5 320.6 1026.8 308.3 1521.8 811.1 306.5 535.8 639.6 4114.3 1928.6 344.0 414.5 319.7 770.3 602.8 169.8 9.1 875.5 574.4 386.0 828.3 559.4 426.0 835.1 819.3 911.5 821.9 1717.4 101.6 306.5 565.2 431.6 536.1 725.9 98.8 14.6 29.9 12.3 17.3 19.7 10.5 13.1 11.7 27.0 7.4 7.0 7.9 12.2 13.6 13.1 21.6 17.6 20.8 12.4 12.1 13.9 18.0 12.8 16.4 15.7 14.1 15.5 15.7 22.6 15.4 94.3 118.6 136.1 2.6 54.9 194.5 354.2 317.7 306.7 1.3 61.3 75.8 0.9 45.8 150.9 58.8 0.0 291.9 50.1 432.7 70.5 285.8 7.9 107.7 65.8 83.0 77.5 155.5 2.1 559.2 1118.2 109.7 153.4 204.4 67.2 110.8 39.3 55.9 276.8 0.0 1.9 190.5 101.7 65.6 121.7 8.4 68.0 163.3 46.2 2.8 265.5 2.8 6.2 1.0 1.4 465.6 330.2 40.6 71.0 206.3 234.1 137.1 51.9 0.6 39.5 84.3 258.2 9.0 65.5 530.8 183.1 161.6 77.6 46.1 187.9 293.4 TXNDC17 "MGC14353, TRP14, TXNL5" ENSG00000129235 "Thioredoxin domain containing 17" Q9BRA2 17 6640985-6644541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 182.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 785.8;Proximal tubular cells: 814.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022931 Approved NA NA 820000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA022931: AB_1858479" "unprognostic (8.94e-2)" "unprognostic (6.03e-2)" "unprognostic (5.33e-2)" "unprognostic (2.97e-2)" "unprognostic (5.02e-2)" "unprognostic (5.06e-2)" "unprognostic (7.65e-3)" "unprognostic (3.88e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-3)" "unprognostic (1.15e-2)" "unprognostic (9.97e-2)" "prognostic unfavorable (1.15e-5)" "unprognostic (8.86e-2)" "unprognostic (2.27e-1)" "unprognostic (3.09e-2)" "unprognostic (9.01e-2)" 25.9 45.3 16.7 22.6 17.3 21.8 28.0 17.7 24.0 35.5 18.5 54.1 56.8 20.4 40.3 182.9 16.1 27.0 31.3 17.8 18.5 62.3 69.8 23.2 22.1 17.3 17.3 13.3 40.4 24.5 27.6 15.0 17.5 32.2 44.7 7.4 47.5 14.6 21.7 27.7 38.8 20.4 18.2 41.9 54.5 15.5 17.2 25.8 20.7 10.1 27.0 68.7 58.5 18.7 130.8 154.4 62.1 134.1 38.1 54.4 29.1 65.4 56.4 59.2 57.0 84.8 44.0 27.8 62.4 50.6 62.3 200.0 67.6 223.5 73.2 93.0 109.3 33.1 138.6 153.3 43.3 54.1 70.7 55.1 83.6 72.7 72.3 58.2 79.8 88.2 45.1 13.3 83.1 91.8 55.1 69.7 90.3 91.9 123.9 53.2 41.4 69.5 126.7 253.3 28.8 74.9 65.9 66.7 54.6 42.1 63.3 48.2 59.8 48.8 61.7 55.7 117.2 20.0 47.8 43.1 98.9 56.9 57.1 77.2 105.0 93.6 35.3 117.3 37.2 54.9 41.7 42.4 115.8 47.5 32.2 37.8 180.9 35.5 120.9 109.3 66.9 56.7 16.7 17.3 17.7 24.0 17.8 18.5 17.3 17.3 17.5 18.2 17.2 18.7 91.8 93.0 157.2 3.9 66.9 189.3 185.3 785.8 330.6 18.1 141.5 162.6 110.3 175.8 236.4 125.0 2.1 180.7 76.6 560.2 389.4 326.8 362.5 110.0 81.6 99.6 135.1 70.7 3.9 451.8 291.6 84.9 181.0 126.9 50.0 92.2 88.2 371.7 245.0 40.4 3.6 316.4 221.8 114.9 83.7 303.2 74.9 118.9 113.8 1.9 170.2 86.8 80.3 4.0 5.3 534.5 378.6 67.0 112.5 169.9 420.3 814.9 142.9 26.8 26.3 58.5 103.9 34.6 116.4 500.1 143.3 104.9 67.7 151.0 332.1 300.0 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 40.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "SiHa: 112.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 1.3 0.2 0.0 0.2 0.0 0.4 0.5 0.8 1.2 0.4 0.3 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.3 0.2 0.7 4.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 5.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.2 0.4 7.1 1.0 0.0 1.8 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 112.2 7.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.8 0.3 0.2 0.2 0.5 0.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 1.3 4.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 40.7 1.7 0.0 0.0 0.0 0.5 8.5 UPK3BL1 "UPK3BL, UPLP" ENSG00000267368 "Uroplakin 3B like 1" B0FP48 7 102637025-102642791 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 272.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.7;Club cells: 3.1;granulocytes: 7.6;Respiratory ciliated cells: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 113.0" HPA011403 Supported NA NA "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA011403: AB_2668503" "unprognostic (4.63e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-2)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (6.19e-3)" "unprognostic (3.35e-1)" "unprognostic (2.88e-1)" "unprognostic (9.39e-3)" "unprognostic (4.00e-1)" "unprognostic (8.11e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.93e-2)" 40.4 36.9 25.6 9.2 26.3 23.4 38.3 26.9 33.2 86.7 32.3 45.1 9.9 44.3 4.4 272.8 50.2 2.8 50.0 27.5 32.9 82.2 59.4 48.3 21.5 30.4 31.0 45.8 53.4 6.9 56.2 4.8 30.5 74.1 4.0 5.6 94.6 55.5 34.7 52.8 62.5 2.4 25.1 98.8 46.6 22.2 25.2 18.2 81.1 12.6 93.6 98.7 172.8 32.5 17.9 13.5 8.6 3.6 3.6 0.5 11.8 0.0 1.9 1.8 4.7 2.0 9.3 2.6 2.9 2.2 2.8 113.0 2.6 12.8 1.6 15.9 19.8 2.6 7.5 4.3 1.0 4.6 4.3 7.1 16.0 0.0 3.0 15.1 16.1 0.2 6.9 8.9 5.7 40.3 7.3 37.8 3.8 15.4 4.2 7.1 4.8 14.7 16.4 13.9 5.9 13.3 23.4 5.9 6.4 7.0 1.7 6.8 5.3 32.2 14.1 11.6 6.8 9.8 4.8 1.6 6.9 10.5 5.4 15.8 3.9 6.7 6.1 3.6 3.1 3.5 3.4 3.4 5.4 3.0 4.4 3.5 5.0 6.2 1.4 4.9 6.0 4.1 25.6 26.3 26.9 33.2 27.5 32.9 30.4 31.0 30.5 25.1 25.2 32.5 0.6 9.6 13.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 3.1 0.0 0.0 0.2 0.7 0.0 0.0 2.2 0.0 0.1 0.4 1.3 0.0 0.0 0.0 0.7 0.1 0.6 0.0 0.2 7.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.0 0.0 1.8 5.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 250.1;Extravillous trophoblasts: 260.3;Macrophages: 199.5;Paneth cells: 260.8" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 362.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.4 9.4 3.8 7.5 4.4 12.5 10.0 3.0 5.8 16.8 2.0 9.8 4.3 3.9 0.8 66.9 5.7 5.9 8.9 3.1 3.9 39.8 11.9 18.8 3.7 4.2 2.8 1.9 4.6 5.0 7.4 3.8 3.7 4.9 5.3 0.5 14.2 1.1 3.7 3.1 6.5 3.4 1.3 20.3 4.1 2.2 4.4 1.2 8.0 0.9 6.6 9.1 31.2 3.7 19.5 26.0 2.4 5.2 8.9 4.0 29.7 7.9 15.5 14.5 17.5 10.8 9.9 0.0 2.5 9.7 89.9 13.9 5.2 46.1 9.4 4.1 4.5 0.8 4.8 4.6 7.4 0.9 1.3 5.0 21.8 6.4 362.8 5.9 9.1 0.4 1.5 13.5 7.6 2.3 0.0 2.9 9.4 4.2 20.7 0.0 4.8 6.0 33.7 11.5 2.3 1.6 10.2 3.0 63.4 29.3 2.4 0.9 12.4 29.6 22.9 7.3 22.6 21.4 34.7 3.7 29.6 3.0 77.8 11.5 16.0 12.2 11.8 12.1 8.9 0.2 7.8 8.7 6.5 0.6 8.1 8.1 6.2 5.4 14.8 0.5 8.4 10.9 3.8 4.4 3.0 5.8 3.1 3.9 4.2 2.8 3.7 1.3 4.4 3.7 107.4 19.2 58.5 5.2 19.1 46.8 26.3 104.4 19.4 27.6 9.0 16.1 11.6 24.3 51.0 11.0 33.3 15.1 122.9 250.1 70.5 50.5 1.0 42.1 22.4 108.1 13.1 4.4 16.5 40.5 260.3 34.1 5.1 91.1 25.9 3.8 72.5 17.5 110.0 16.8 29.4 35.0 85.5 130.5 118.1 2.4 5.3 199.5 87.2 1.0 61.4 13.3 71.1 4.0 3.6 117.9 260.8 2.2 30.3 30.4 42.8 23.3 11.9 29.2 6.6 21.1 32.2 0.3 9.5 42.9 29.8 78.7 71.0 1.5 29.1 34.9 USH1G "ANKS4A, FLJ33924, Sans" ENSG00000182040 "USH1 protein network component sans" Q495M9 17 74916083-74923256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 7.8;skin 1: 2.8" "Group enriched" "Detected in some" 5 "Early spermatids: 8.2;Late spermatids: 17.9;Muller glia cells: 11.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.8;hTCEpi: 1.6;K-562: 1.3;MCF7: 2.0;OE19: 1.9" "Region enriched" "Detected in single" 12 "olfactory bulb: 9.9" "Not detected" "Not detected" HPA024360 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA024360: AB_1858660" "unprognostic (2.95e-1)" "unprognostic (6.17e-2)" "unprognostic (6.34e-4)" "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.74e-1)" "unprognostic (5.59e-4)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (3.10e-4)" "unprognostic (1.57e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-2)" 0.0 0.9 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.3 0.0 0.0 0.1 0.8 1.9 7.8 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 0.0 2.8 0.2 0.5 0.0 0.0 0.0 1.8 0.6 0.1 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.8 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.2 0.1 0.3 0.1 0.1 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.3 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 2.3 0.4 0.0 0.0 1.7 0.6 0.0 0.2 0.0 0.0 0.1 0.2 0.4 1.6 0.3 0.3 0.0 0.1 0.0 0.1 USP6NL "KIAA0019, RN-tre, RNTRE, TRE2NL, USP6NL-IT1" ENSG00000148429 "USP6 N-terminal like" Q92738 10 11453946-11611754 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 145.2;Oligodendrocyte precursor cells: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.0;naive B-cell: 3.4" "Lineage enriched" "Detected in single" 4 "B-cells: 4.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039196 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "HPA039196: AB_10795031" "unprognostic (1.64e-1)" "unprognostic (2.93e-1)" "unprognostic (6.84e-2)" "unprognostic (3.33e-2)" "unprognostic (1.35e-3)" "prognostic favorable (8.06e-4)" "unprognostic (2.39e-1)" "unprognostic (2.44e-2)" "unprognostic (4.22e-2)" "unprognostic (4.20e-2)" "unprognostic (1.86e-2)" "unprognostic (8.54e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-2)" "unprognostic (3.58e-2)" "unprognostic (1.49e-1)" "unprognostic (8.54e-2)" 5.4 6.8 4.8 7.3 5.2 8.6 5.5 6.5 4.3 6.5 6.0 5.8 5.5 5.9 7.7 22.9 8.9 5.7 4.5 4.8 6.0 5.6 16.3 6.5 14.9 7.5 6.3 7.5 5.1 5.4 4.6 6.8 7.5 4.7 7.4 13.0 6.9 5.2 1.7 8.1 5.8 5.7 6.9 13.6 7.3 24.6 6.4 7.4 5.2 2.2 18.5 5.6 9.7 7.5 26.9 11.6 24.5 10.7 6.1 7.4 11.9 7.3 6.3 8.2 11.3 14.3 24.8 33.5 7.0 6.3 6.7 14.6 11.2 7.9 12.0 0.1 8.7 14.3 6.6 25.5 7.3 4.2 2.0 4.2 11.6 9.5 5.6 9.5 19.8 11.5 22.6 0.8 7.0 18.6 11.6 3.1 12.5 25.0 6.0 22.2 6.4 4.3 11.6 7.9 7.8 13.7 7.9 24.0 25.3 10.2 17.8 4.4 10.8 4.2 15.4 10.9 7.1 0.0 0.9 22.0 7.1 5.1 11.5 0.8 0.5 0.8 0.0 0.9 0.1 4.0 0.1 0.1 0.7 3.4 0.1 0.1 0.3 0.5 0.6 0.6 0.0 0.3 4.8 5.2 6.5 4.3 4.8 6.0 7.5 6.3 7.5 6.9 6.4 7.5 12.0 3.2 17.5 23.2 37.7 6.8 20.6 7.8 13.6 6.0 9.6 6.6 7.8 2.8 12.4 1.8 29.2 7.6 0.5 8.2 7.9 10.8 17.4 32.5 9.7 11.1 13.8 14.3 16.0 10.6 7.5 6.8 20.4 33.2 0.0 11.8 5.7 14.1 8.6 6.7 24.3 14.0 8.2 16.3 8.7 15.4 4.7 12.7 12.4 145.2 7.5 11.2 3.1 68.3 29.4 16.1 6.8 4.9 20.0 20.8 4.2 9.0 15.6 14.6 0.0 5.2 9.1 21.5 7.2 20.1 9.9 7.3 3.9 7.7 7.1 48.3 VSIG10L ENSG00000186806 "V-set and immunoglobulin domain containing 10 like" Q86VR7 19 51331536-51342124 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 20.3;esophagus: 62.3;salivary gland: 23.5;vagina: 22.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 10.1;Melanocytes: 5.4;Sertoli cells: 6.6;Squamous epithelial cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 4.7;OE19: 11.0;T-47d: 8.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA060453, HPA066745" Uncertain Approved Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA060453: AB_2684280, HPA066745: AB_2685712" "unprognostic (1.70e-2)" "unprognostic (1.95e-2)" "unprognostic (1.30e-2)" "unprognostic (2.98e-3)" "unprognostic (1.08e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.75e-4)" "unprognostic (2.40e-3)" "unprognostic (2.78e-1)" "unprognostic (9.87e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.90e-4)" "unprognostic (1.42e-2)" "unprognostic (8.51e-2)" "unprognostic (7.74e-2)" "unprognostic (5.19e-3)" 0.2 0.1 0.1 0.0 0.4 0.1 0.8 0.8 0.5 20.3 0.0 0.1 0.0 0.0 0.0 62.3 0.1 0.3 0.1 0.1 0.7 0.1 0.7 0.1 0.1 0.5 1.0 0.2 0.0 0.0 0.1 0.0 0.8 1.2 0.0 0.0 23.5 0.1 0.1 10.6 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.1 0.1 0.0 6.3 0.2 22.3 0.7 0.0 0.9 0.0 0.3 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.7 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.1 0.2 4.7 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.4 1.3 0.0 0.4 0.0 0.1 0.6 11.0 0.4 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 8.4 0.0 0.0 0.0 0.1 0.7 0.0 1.1 0.7 0.1 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.8 0.5 0.1 0.7 0.5 1.0 0.8 0.1 0.6 0.7 1.2 0.0 0.5 1.3 0.8 0.6 1.1 0.6 1.8 1.6 2.2 1.8 0.9 0.0 0.1 0.0 0.0 0.4 0.2 0.9 0.0 1.1 0.2 0.0 0.3 0.5 1.2 0.0 0.6 0.0 0.9 1.6 1.1 0.2 1.3 1.0 1.4 1.2 4.5 10.1 1.0 0.5 0.0 3.2 0.9 0.7 2.1 2.4 5.4 1.0 1.1 1.4 0.0 0.0 0.9 0.4 1.3 4.1 0.1 1.0 1.6 0.9 0.0 0.6 6.6 1.5 1.2 0.5 2.6 6.1 0.4 0.5 0.4 2.2 0.7 0.7 WDR4 "TRM82, TRMT82" ENSG00000160193 "WD repeat domain 4" P57081 21 42843094-42879568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 25.8;Prostatic glandular cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017381 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA017381: AB_1858807" "unprognostic (3.47e-2)" "unprognostic (2.15e-2)" "unprognostic (4.32e-2)" "unprognostic (2.13e-2)" "unprognostic (2.95e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (5.48e-7)" "unprognostic (2.85e-3)" "unprognostic (5.37e-2)" "unprognostic (2.27e-2)" "unprognostic (4.25e-1)" "unprognostic (4.78e-2)" "unprognostic (2.65e-2)" "unprognostic (1.74e-3)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.46e-2)" 5.1 4.7 4.0 7.2 3.9 6.7 3.9 3.8 4.8 4.3 3.4 3.8 5.0 5.1 1.9 9.1 4.1 1.8 3.5 3.8 3.4 4.8 6.0 3.8 9.3 4.3 3.9 4.3 5.6 2.9 2.3 4.1 4.4 3.4 3.1 1.6 3.6 2.6 6.7 5.0 4.0 3.3 3.9 5.4 3.6 4.7 4.0 5.3 4.1 3.2 7.3 5.7 5.0 4.5 35.7 48.5 12.9 18.5 6.9 8.2 30.7 20.2 7.3 16.9 10.7 48.9 18.1 58.8 11.5 14.5 24.5 19.3 44.7 25.5 11.8 19.2 42.0 59.7 52.0 41.9 13.3 36.8 14.5 4.7 11.2 22.9 16.4 6.3 22.1 20.9 72.6 22.0 14.8 29.4 38.5 20.9 32.3 26.4 47.0 41.6 7.8 58.4 12.8 21.2 30.4 19.5 21.2 31.1 10.2 4.1 20.4 28.2 16.4 25.9 17.3 12.1 41.0 28.9 21.6 48.1 12.5 57.2 31.1 0.0 3.9 0.2 2.4 6.8 3.6 5.4 3.4 3.1 7.1 4.9 3.4 3.5 0.0 3.6 4.2 3.5 4.4 3.5 4.0 3.9 3.8 4.8 3.8 3.4 4.3 3.9 4.4 3.9 4.0 4.5 3.6 0.0 4.8 5.5 10.3 8.5 12.7 7.3 4.0 4.1 5.3 4.6 2.5 0.0 3.2 0.0 2.1 16.3 5.5 5.9 0.0 7.4 4.8 2.8 5.8 5.2 5.4 8.4 4.8 6.7 25.8 4.7 6.1 3.4 10.2 5.4 3.6 7.0 12.5 3.3 4.5 6.0 4.1 3.5 4.0 3.8 2.8 4.7 7.2 2.8 1.9 3.8 2.1 1.5 5.1 6.9 1.0 3.0 15.3 24.6 3.5 6.8 2.1 4.6 6.6 2.7 6.1 10.4 8.4 7.5 10.9 11.5 3.6 8.2 7.7 10.7 YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005065 Approved NA NA 320000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB005065: AB_2218378" "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.28e-5)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" 379.0 262.9 246.2 374.2 324.1 527.2 251.7 147.4 343.0 269.6 88.3 475.2 327.3 275.6 220.9 892.8 243.9 333.0 187.3 366.2 269.6 224.9 190.9 275.8 429.3 163.3 195.7 227.7 191.5 233.3 109.0 339.2 222.5 265.8 445.9 285.3 244.8 291.2 95.0 399.4 375.4 356.5 170.1 272.8 365.4 226.8 276.9 434.8 289.7 168.9 566.1 501.0 343.2 205.0 1902.4 879.2 1605.4 457.7 396.6 490.9 808.0 877.6 1099.2 1124.6 1098.2 602.4 1149.5 816.5 857.1 1349.3 937.2 785.0 1025.5 1213.5 1630.1 765.1 454.2 779.5 579.0 378.1 524.8 311.5 840.3 475.4 1524.0 936.7 1430.1 923.8 1008.7 584.9 887.8 758.9 920.2 660.6 1357.1 535.4 548.0 2269.0 1026.7 569.7 468.6 544.8 1023.1 963.5 889.7 642.7 669.5 609.8 1365.4 1094.7 896.0 374.6 879.0 554.6 834.3 693.7 798.3 503.6 625.3 994.6 925.8 595.2 2303.2 1340.5 427.5 705.8 559.0 589.1 559.3 484.8 463.3 537.3 497.3 395.9 348.3 441.8 616.5 503.7 726.9 313.4 663.9 1087.2 246.2 324.1 147.4 343.0 366.2 269.6 163.3 195.7 222.5 170.1 276.9 205.0 199.4 250.0 228.9 43.1 637.6 1007.0 438.4 309.3 507.6 120.4 285.9 209.9 87.0 188.8 321.3 263.0 89.6 243.4 491.2 552.7 121.3 405.2 1092.9 359.6 245.6 216.0 265.3 137.3 150.2 421.3 551.6 277.4 448.5 578.8 452.9 122.1 183.1 104.5 276.3 134.6 92.5 525.2 244.1 303.5 641.2 2118.0 125.6 456.9 391.3 56.2 334.9 110.9 407.8 51.3 91.5 771.0 452.7 147.1 457.2 427.2 310.6 160.4 292.0 96.3 131.5 229.4 290.4 170.2 92.6 908.0 1184.7 408.9 596.5 116.5 371.7 794.9 ZBTB5 KIAA0354 ENSG00000168795 "Zinc finger and BTB domain containing 5" O15062 9 37438102-37465450 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021521 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA021521: AB_2670736" "unprognostic (2.36e-2)" "unprognostic (2.78e-2)" "unprognostic (5.22e-2)" "unprognostic (6.35e-2)" "unprognostic (1.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.96e-3)" "unprognostic (5.81e-2)" "unprognostic (3.95e-2)" "unprognostic (1.43e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" "unprognostic (1.27e-3)" "unprognostic (5.73e-3)" "unprognostic (2.30e-1)" "unprognostic (2.77e-3)" "unprognostic (1.80e-1)" 4.9 6.2 4.9 5.6 5.8 13.6 7.4 5.9 5.0 6.3 5.0 6.1 6.3 6.3 7.7 17.8 5.9 5.4 5.5 4.7 5.0 7.4 12.9 7.9 9.0 5.7 5.3 8.4 8.4 7.6 4.7 6.2 5.5 7.2 5.8 9.2 7.8 6.7 5.2 11.9 7.2 5.3 5.0 7.2 7.2 8.8 5.2 9.5 10.3 7.2 12.1 5.6 9.3 7.8 9.3 10.5 26.6 16.6 6.7 4.7 11.4 7.5 5.8 9.0 7.4 7.8 6.7 18.8 7.9 5.6 6.6 11.1 17.5 6.2 6.9 13.9 9.1 6.9 28.7 9.1 6.5 8.6 5.8 4.5 15.5 4.5 9.5 10.2 10.2 14.8 16.6 15.6 6.8 5.9 18.2 6.3 6.8 10.0 5.3 16.3 12.8 7.2 8.7 8.2 12.2 21.9 7.3 11.7 5.8 13.3 18.7 8.3 7.0 6.3 17.3 3.7 7.2 8.3 9.8 16.3 5.8 7.3 6.8 0.1 0.4 0.0 0.6 0.2 0.7 0.9 0.5 0.5 0.8 0.7 0.8 0.9 0.0 0.3 0.0 0.2 0.5 0.3 4.9 5.8 5.9 5.0 4.7 5.0 5.7 5.3 5.5 5.0 5.2 7.8 4.0 16.0 6.5 12.7 5.1 14.3 8.8 5.0 11.4 2.0 8.4 6.6 3.2 7.2 9.3 1.8 6.2 3.9 3.7 6.5 0.0 4.0 2.2 7.3 4.2 5.6 8.4 2.1 8.9 3.2 2.2 4.2 5.1 7.3 1.3 6.6 3.6 8.6 2.4 13.5 9.1 5.2 4.1 1.9 4.8 5.3 4.1 3.4 3.6 10.3 3.7 3.3 1.0 13.6 15.5 4.1 3.7 3.8 4.2 12.6 3.1 3.5 6.0 5.1 0.0 5.4 4.0 7.5 7.9 17.9 18.2 5.7 2.7 4.4 5.1 8.2 ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Basal squamous epithelial cells: 45.5;Distal enterocytes: 52.5;Excitatory neurons: 48.8;Gastric mucus-secreting cells: 49.5;Oligodendrocyte precursor cells: 51.3;Squamous epithelial cells: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RT4: 42.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.83e-3)" "unprognostic (6.60e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (3.85e-3)" "unprognostic (2.89e-2)" 5.3 11.2 7.8 2.0 3.9 0.4 6.1 3.6 5.4 8.4 0.0 14.5 1.8 1.7 17.2 40.8 14.0 3.4 1.6 4.6 8.1 1.9 0.9 4.5 0.6 7.6 6.6 6.5 1.0 5.2 1.8 3.7 4.3 3.2 13.4 6.3 14.7 3.9 1.7 22.4 2.9 2.1 5.0 9.2 13.8 9.2 14.7 0.3 16.7 1.6 3.8 11.0 19.5 4.8 0.0 0.0 1.5 1.2 0.2 0.4 0.8 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.5 0.0 1.7 2.7 0.1 0.4 0.2 0.3 1.3 0.2 3.2 0.1 0.0 0.0 0.4 0.1 0.7 0.2 0.4 0.0 0.0 1.2 0.0 0.1 0.6 0.7 1.7 0.5 0.5 8.6 0.0 0.1 0.0 9.7 1.3 42.7 5.4 6.9 0.6 0.3 0.0 1.4 0.9 0.0 0.0 0.1 0.6 0.5 0.0 0.1 0.2 0.0 2.7 0.1 0.2 1.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 7.8 3.9 3.6 5.4 4.6 8.1 7.6 6.6 4.3 5.0 14.7 4.8 0.5 6.4 1.5 47.0 0.1 6.1 5.3 11.6 45.5 1.2 6.0 8.4 3.1 12.8 9.5 1.8 0.0 13.7 0.1 52.5 0.0 1.0 9.6 4.8 1.8 2.9 4.8 0.0 48.8 4.0 0.8 3.4 49.5 6.7 0.0 1.0 0.0 0.6 1.5 1.7 7.0 30.8 6.1 2.1 0.8 4.4 3.7 0.4 3.6 22.5 0.1 1.0 0.0 51.3 2.1 1.2 14.6 12.0 0.0 7.5 3.5 0.0 7.6 2.5 13.1 8.8 11.9 0.9 0.9 96.9 8.8 12.6 0.2 6.6 18.3 13.7 ZNF426 MGC2663 ENSG00000130818 "Zinc finger protein 426" Q9BUY5 19 9523223-9538645 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029342 Approved Approved Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029342: AB_10603007" "unprognostic (3.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-2)" "unprognostic (6.62e-2)" "prognostic favorable (3.74e-4)" "unprognostic (4.34e-2)" "unprognostic (1.77e-2)" "unprognostic (4.75e-3)" "unprognostic (1.05e-3)" "unprognostic (8.89e-3)" "unprognostic (7.41e-3)" "prognostic favorable (2.57e-6)" "unprognostic (1.05e-1)" "unprognostic (3.17e-2)" "unprognostic (2.49e-1)" "prognostic favorable (1.81e-4)" 5.1 3.3 3.1 3.9 4.0 5.7 6.9 5.4 3.4 5.5 4.9 4.1 2.8 7.6 4.5 20.6 5.8 4.3 5.4 3.2 2.9 4.3 2.2 5.1 4.1 3.4 3.4 9.2 4.3 6.3 2.4 5.6 3.4 5.9 3.8 5.1 4.0 5.3 3.7 4.1 2.9 7.8 2.9 4.7 3.7 4.8 3.8 5.7 6.7 5.5 5.7 4.7 5.8 6.0 5.7 1.8 11.2 11.8 7.4 9.7 6.2 7.1 10.8 9.4 11.4 2.4 2.5 5.7 5.6 6.9 6.6 4.8 11.7 8.4 14.0 2.7 9.0 23.7 9.5 4.3 6.7 0.7 7.4 12.4 7.1 10.5 15.0 10.2 10.2 9.7 9.6 0.5 9.1 0.3 13.7 11.4 14.0 1.3 4.4 7.4 13.9 5.9 5.1 14.7 6.3 8.5 12.1 4.3 9.7 9.5 6.0 5.5 8.3 13.2 7.7 6.0 7.7 6.4 9.7 4.8 1.9 0.3 9.6 10.0 3.2 6.1 8.8 4.5 7.8 7.6 6.8 8.7 3.8 6.5 10.0 9.3 6.7 7.8 6.3 3.4 7.1 3.4 3.1 4.0 5.4 3.4 3.2 2.9 3.4 3.4 3.4 2.9 3.8 6.0 15.0 28.9 26.5 3.3 13.2 3.4 15.6 3.2 12.5 24.8 17.1 14.6 10.1 5.7 12.4 7.3 20.9 12.8 13.4 3.8 21.5 10.9 33.5 11.5 14.2 16.4 3.6 12.6 5.4 4.2 10.2 12.4 5.1 15.5 28.4 22.4 14.3 3.0 7.6 37.0 3.9 4.2 12.2 8.9 1.6 8.2 17.1 8.2 3.6 5.6 11.2 20.1 15.5 4.5 4.7 6.9 5.1 22.2 6.7 13.3 4.7 5.4 14.6 22.0 6.6 17.9 13.2 12.2 11.8 14.7 2.8 14.2 12.1 12.3 6.3 17.9 ZSWIM4 FLJ12221 ENSG00000132003 "Zinc finger SWIM-type containing 4" Q9H7M6 19 13795460-13832230 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 16.6" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 34.2;Urothelial cells: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042084 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA042084: AB_10795392" "unprognostic (3.29e-2)" "unprognostic (4.07e-1)" "unprognostic (4.15e-2)" "unprognostic (1.41e-3)" "unprognostic (4.78e-2)" "unprognostic (1.34e-3)" "unprognostic (4.25e-3)" "unprognostic (6.14e-2)" "unprognostic (5.36e-2)" "unprognostic (1.56e-2)" "unprognostic (1.78e-1)" "unprognostic (6.15e-2)" "prognostic unfavorable (7.85e-5)" "unprognostic (3.47e-1)" "unprognostic (4.95e-1)" "unprognostic (1.86e-1)" "unprognostic (8.63e-2)" 3.3 5.3 0.8 2.0 0.8 1.0 4.9 0.9 1.9 5.6 1.4 2.8 1.1 4.2 0.2 16.6 3.3 1.4 4.1 0.8 1.2 6.2 1.9 7.1 1.2 1.5 1.2 3.6 3.9 1.0 4.7 1.6 1.3 5.0 0.3 1.1 14.8 0.8 2.9 8.5 3.0 0.9 0.8 4.1 3.5 1.4 1.4 1.4 5.8 0.8 1.3 3.2 7.6 0.9 4.3 2.4 4.7 2.4 0.6 0.5 4.5 1.8 3.9 1.6 1.7 0.9 2.3 1.5 2.8 1.5 2.5 1.7 0.8 1.6 1.1 5.4 1.5 0.2 3.0 0.5 3.8 0.4 1.2 2.5 0.4 1.8 0.7 3.9 3.8 3.6 1.4 3.2 0.5 2.3 2.4 3.4 5.5 0.8 2.4 5.3 4.4 2.5 2.2 2.0 1.3 9.1 3.1 7.6 3.3 2.7 1.1 2.8 4.5 4.7 1.7 1.4 6.2 3.9 2.5 1.0 3.0 1.8 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.9 1.9 0.8 1.2 1.5 1.2 1.3 0.8 1.4 0.9 5.5 3.2 2.0 4.9 2.4 5.4 17.1 8.6 2.8 5.4 11.9 6.9 3.3 8.6 7.4 3.7 8.4 4.2 2.0 3.3 0.0 13.1 0.2 11.1 5.0 10.4 10.7 1.7 5.8 23.1 3.4 6.0 4.1 23.0 0.0 3.7 4.6 1.8 4.6 6.7 7.0 3.0 2.0 7.0 11.9 0.4 1.2 5.6 3.6 5.6 3.8 2.4 0.0 6.0 1.8 23.8 2.3 1.2 1.5 14.3 3.9 3.2 12.6 3.7 0.0 34.2 6.4 0.3 0.9 4.9 7.0 6.0 6.8 0.7 3.9 26.8