Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Excitatory neurons: 21.4;Inhibitory neurons: 19.9;Microglial cells: 30.9;Skeletal myocytes: 15.9;Smooth muscle cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 7.2;hTERT-RPE1: 7.5;NB-4: 37.0;REH: 9.8" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA040223: AB_10795376" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-4)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (6.86e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-2)" 15.9 8.2 7.1 2.3 7.3 1.8 9.5 5.0 11.9 13.0 5.8 7.3 0.8 12.7 0.7 4.1 10.2 1.9 8.5 7.6 8.7 6.9 6.3 8.2 3.2 7.1 6.8 8.3 7.8 0.8 4.1 1.7 6.7 8.4 0.5 0.4 4.1 1.5 2.8 8.8 6.3 1.5 6.0 5.4 3.8 2.4 8.1 1.4 6.2 0.8 1.3 5.7 8.7 6.5 0.0 4.6 2.5 0.0 0.4 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 7.2 0.0 0.3 0.0 0.1 1.8 0.0 0.0 0.0 7.5 0.1 0.3 0.1 0.0 0.0 0.0 0.3 37.0 1.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.2 0.1 0.4 2.0 3.1 4.4 2.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 7.3 5.0 11.9 7.6 8.7 7.1 6.8 6.7 6.0 8.1 6.5 5.6 0.0 0.0 18.3 0.3 1.7 0.6 0.1 0.0 1.5 1.2 1.5 1.3 5.7 0.1 0.0 0.0 0.1 6.9 0.0 0.0 8.8 5.1 0.4 7.4 5.8 0.0 1.3 21.4 0.5 0.0 6.4 1.1 0.4 0.0 1.8 6.8 2.0 0.9 0.0 19.9 0.3 0.0 2.7 6.0 2.4 7.5 3.3 0.0 30.9 0.6 0.8 11.3 9.5 1.2 0.9 0.0 6.0 1.3 0.2 0.0 0.1 0.0 0.2 6.6 15.9 15.0 0.1 0.4 0.1 0.9 0.4 3.2 0.6 0.1 0.3 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 52.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Cardiomyocytes: 8.3;Collecting duct cells: 5.5;Ionocytes: 2.0" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" 0.1 0.2 2.8 0.1 4.1 0.0 0.1 5.6 2.6 0.3 1.6 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 2.7 2.5 52.7 0.3 0.1 0.0 4.9 4.6 0.0 0.1 0.2 0.2 0.0 5.2 0.2 0.0 0.2 1.0 0.2 0.0 0.3 0.2 0.1 3.4 0.0 0.4 2.4 6.1 0.0 0.0 0.0 0.0 0.1 0.1 3.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 1.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 5.6 2.6 2.7 2.5 4.9 4.6 5.2 3.4 6.1 3.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.6 0.0 0.1 0.4 0.3 8.3 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.2 0.6 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ARHGEF33 ENSG00000214694 "Rho guanine nucleotide exchange factor 33" A8MVX0 2 38889875-38975454 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.8;Excitatory neurons: 15.2;Late spermatids: 26.8;Spermatocytes: 34.7;Spermatogonia: 35.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Group enriched" "Detected in some" 4 "BEWO: 5.6;HeLa: 2.6;SiHa: 7.2" "Region enriched" "Detected in many" 32 "cerebellum: 280.4" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "HPA034661, HPA041051" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA034661: AB_10669679, HPA041051: AB_2677274" "unprognostic (8.38e-2)" "unprognostic (7.05e-4)" "unprognostic (1.95e-1)" "unprognostic (4.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-1)" "unprognostic (3.66e-1)" "unprognostic (3.37e-1)" "unprognostic (5.82e-2)" "unprognostic (2.05e-3)" "unprognostic (4.99e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" 0.4 2.1 4.9 0.6 5.2 0.0 0.9 22.6 5.8 1.5 4.4 1.0 0.1 1.5 2.6 0.4 1.4 0.8 0.5 4.9 4.1 0.9 0.2 0.7 0.3 4.1 5.4 3.5 0.4 0.7 3.4 0.5 4.0 0.9 0.3 4.0 0.5 0.7 0.3 0.8 0.4 0.5 3.1 0.3 0.5 5.7 7.2 0.1 1.1 0.0 0.2 0.7 0.7 5.0 0.2 0.0 0.2 0.1 0.1 0.1 5.6 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.1 2.6 0.1 0.4 0.2 0.1 0.5 0.6 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.3 0.2 7.2 0.3 0.0 0.6 0.0 0.2 0.4 0.1 0.9 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.2 3.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.9 5.2 22.6 5.8 4.9 4.1 4.1 5.4 4.0 3.1 7.2 5.0 0.4 0.0 1.5 7.8 0.1 0.0 0.1 0.0 0.6 2.5 0.3 0.6 0.8 1.5 0.6 0.0 0.0 1.1 0.0 0.1 0.0 0.1 34.8 1.8 1.2 0.4 0.0 2.7 15.2 0.0 1.9 1.2 0.0 0.2 0.0 1.4 0.0 0.2 1.0 0.0 11.4 0.4 0.0 0.0 0.0 26.8 1.2 0.2 0.0 1.9 0.1 3.6 0.0 5.5 3.4 0.0 0.0 3.4 0.0 0.1 0.0 0.4 3.9 2.9 0.0 0.3 1.5 34.7 35.6 0.1 0.1 0.5 0.0 2.0 0.1 0.2 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;liver: 3.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Excitatory neurons: 1.7;Hepatocytes: 1.1;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 7.5" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" HPA027008 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027008: AB_10600783" "unprognostic (7.17e-2)" "unprognostic (2.81e-1)" "unprognostic (7.66e-2)" "unprognostic (1.86e-2)" "unprognostic (2.20e-3)" "unprognostic (7.40e-2)" "unprognostic (7.76e-2)" "unprognostic (6.16e-2)" "unprognostic (2.46e-1)" "unprognostic (9.28e-4)" "unprognostic (4.96e-3)" "unprognostic (1.17e-1)" "unprognostic (5.06e-4)" "unprognostic (1.72e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (7.18e-2)" 0.1 0.2 1.4 0.0 1.5 0.0 0.1 3.0 2.0 0.1 0.7 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 2.0 1.0 1.2 3.0 0.0 0.0 0.8 0.8 0.1 0.4 0.0 0.2 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 7.5 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 3.0 2.0 2.0 1.0 0.8 0.8 0.8 0.8 0.8 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 1.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.3 0.5 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 101.5;salivary gland: 185.3" "Cell type enhanced" "Detected in many" "B-cells: 82.5;Distal enterocytes: 120.7;Enteroendocrine cells: 97.8;Gastric mucus-secreting cells: 153.4;Intestinal goblet cells: 128.4;Plasma cells: 96.0;Undifferentiated cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 186.8;HMC-1: 266.1;JURKAT: 152.1;MOLT-4: 253.2;SK-BR-3: 195.2" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 6.8 13.7 6.8 62.2 8.7 98.3 7.7 20.0 6.1 6.0 15.3 55.0 30.7 9.1 1.6 9.7 6.1 13.7 8.0 3.0 4.5 11.4 4.6 22.4 101.5 2.3 12.8 3.1 64.0 2.1 2.5 2.8 3.9 20.3 33.0 0.2 185.3 19.6 3.3 28.2 75.3 6.3 2.0 98.2 92.8 2.1 11.6 97.5 11.7 3.3 58.7 17.0 7.2 2.3 0.3 7.6 0.3 6.8 0.0 0.0 0.3 0.4 0.9 0.2 0.6 2.5 1.7 186.8 11.0 0.6 0.1 0.8 3.1 0.0 0.0 23.5 2.1 98.0 6.0 0.1 1.7 108.0 266.1 0.2 0.0 0.7 0.0 0.1 0.3 152.1 20.1 117.1 0.1 116.8 253.2 115.5 1.2 53.1 1.6 27.5 0.2 43.3 0.0 3.3 11.5 3.4 1.5 195.2 0.2 1.1 12.2 26.3 0.5 0.0 2.1 0.4 0.1 43.4 14.2 66.0 2.5 75.6 0.1 16.0 1.4 33.7 10.8 0.9 8.3 9.8 6.7 10.3 1.6 11.4 4.8 6.0 13.1 3.8 0.5 15.8 6.4 6.7 6.8 8.7 20.0 6.1 3.0 4.5 2.3 12.8 3.9 2.0 11.6 2.3 7.1 0.0 1.9 0.7 82.5 0.9 0.4 0.7 1.2 0.0 4.7 1.7 3.8 2.8 2.7 23.9 0.0 0.2 59.2 120.7 0.0 1.3 0.1 0.3 0.4 7.8 97.8 22.5 0.5 12.1 0.3 1.9 153.4 0.3 33.0 0.2 8.9 1.0 2.8 0.0 0.6 128.4 36.7 3.1 2.5 0.2 0.0 17.8 12.4 5.6 5.0 0.2 28.8 0.0 0.3 25.2 50.3 0.7 96.0 4.2 14.0 0.4 2.7 0.2 0.0 1.0 3.4 0.0 1.5 0.4 0.3 0.0 38.4 0.4 65.6 4.6 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 BARHL2 ENSG00000143032 "BarH like homeobox 2" Q9NY43 1 90711539-90717302 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 27.4" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 23.5" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 27.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.0;HEK 293: 3.7;HMC-1: 1.0" "Region enriched" "Detected in many" 5 "cerebellum: 12.9" "Region enriched" "Detected in some" 20 "cerebellum: 24.6" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.83e-1)" "unprognostic (1.73e-1)" "unprognostic (6.80e-2)" "unprognostic (3.10e-1)" "unprognostic (1.60e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 27.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 27.4 0.7 0.0 1.2 0.1 1.9 1.9 0.3 2.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2;stomach 1: 18.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 67.6;Exocrine glandular cells: 115.9;Intestinal goblet cells: 39.3;Pancreatic endocrine cells: 74.9;Proximal enterocytes: 133.2;Undifferentiated cells: 54.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 16.9;EFO-21: 5.4;OE19: 15.2;RPTEC TERT1: 5.5" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA029732: AB_10599615, HPA029733: AB_10600422" "unprognostic (5.96e-2)" "unprognostic (6.41e-3)" "unprognostic (5.82e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.16e-1)" "unprognostic (6.23e-3)" "unprognostic (4.97e-4)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-7)" "unprognostic (5.20e-2)" "unprognostic (2.24e-2)" "unprognostic (9.04e-3)" "unprognostic (4.27e-2)" 0.2 0.1 1.2 3.1 1.4 13.2 0.5 2.7 1.9 3.9 0.4 32.5 43.2 1.0 5.2 2.2 0.6 8.3 0.2 1.4 1.4 0.7 0.2 0.5 0.2 1.2 1.7 0.1 9.6 0.1 0.1 0.1 1.1 0.3 26.9 1.3 0.3 0.2 0.3 0.2 41.8 0.8 0.8 0.5 18.4 0.8 1.1 1.2 0.1 0.0 0.2 0.5 0.6 1.3 0.0 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.3 0.1 0.0 15.2 0.0 0.1 0.3 0.6 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.3 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 1.4 2.7 1.9 1.4 1.4 1.2 1.7 1.1 0.8 1.1 1.3 0.6 0.0 1.3 2.0 0.9 0.4 5.0 3.4 2.2 1.6 0.3 0.3 0.4 4.3 12.2 23.9 6.2 0.1 1.0 67.6 0.0 4.1 1.4 4.3 0.5 1.2 2.4 0.0 2.3 115.9 0.0 1.2 29.6 5.5 0.0 0.4 0.0 0.3 0.8 1.7 1.8 39.3 6.1 0.6 5.0 0.2 0.0 1.6 0.0 0.0 2.5 0.3 0.0 0.5 1.6 74.9 23.3 0.0 1.0 2.7 133.2 0.4 6.3 2.6 0.0 6.6 2.2 0.6 0.6 2.0 1.1 0.1 1.8 0.4 54.9 14.9 BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.2;lung: 18.3;pituitary gland: 12.1" "Cell type enriched" "Detected in some" 6 "Club cells: 1205.8" "Cancer enriched" "Detected in many" 27 "lung cancer: 262.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" NA NA 1200000 "Cluster 19: Lung - Lung function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025669: " "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 129.5 0.0 0.0 0.0 0.0 0.0 0.0 1205.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 126.1 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.0 80.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 C1orf232 ENSG00000282872 "Chromosome 1 open reading frame 230" A0A0U1RR37 1 26164101-26168963 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SCLC-21H: 2.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.6" "Not detected" "Not detected" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.6" "Group enriched" "Detected in many" 16 "Adipocytes: 704.2;Distal enterocytes: 1289.3;Paneth cells: 2368.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 99.5" "Lineage enriched" "Detected in single" 995 "granulocytes: 99.5" "Cell line enhanced" "Detected in single" "OE19: 1.1" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" 83.0 2.3 17.8 3.1 18.8 19.5 80.9 86.8 34.2 12.7 13.9 263.6 3.8 6.0 51.9 1.0 5.0 38.3 55.2 22.8 13.9 47.6 0.7 87.2 0.6 13.4 17.8 6.2 31.8 16.9 15.7 8.6 22.8 8.2 172.6 0.1 10.4 36.9 30.5 3.8 11.2 2.7 12.7 16.0 10.0 1.3 15.1 1.6 74.6 42.3 0.1 6.2 5.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 99.5 0.0 0.0 0.0 0.0 0.1 17.8 18.8 86.8 34.2 22.8 13.9 13.4 17.8 22.8 12.7 15.1 14.9 704.2 0.0 2.4 1.3 1.5 1.5 0.3 0.0 2.2 0.0 2.3 2.5 9.1 0.0 0.6 14.7 0.0 0.0 1.2 1289.3 33.2 11.7 0.5 0.6 13.0 88.3 19.3 0.0 3.8 0.2 0.0 4.4 0.0 0.2 11.4 23.2 1.4 0.0 0.6 0.0 1.4 24.6 0.0 0.0 1.2 0.1 0.6 1.1 0.0 23.4 0.0 0.1 0.0 1.0 0.4 0.1 2368.3 0.0 1.2 0.1 14.9 72.4 0.7 0.0 6.6 5.0 23.4 0.1 0.0 0.1 1.1 0.0 2.4 0.4 41.7 0.3 CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Enteroendocrine cells: 35.2;Gastric mucus-secreting cells: 40.2;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cell line enhanced" "Detected in some" "HEK 293: 10.1;JURKAT: 11.0;K-562: 20.3;NB-4: 12.3;OE19: 17.4" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" 1.6 0.9 5.2 0.3 5.8 0.5 4.6 18.3 5.6 4.3 2.0 1.3 1.0 1.9 10.2 0.2 1.5 0.3 4.3 4.4 5.3 5.3 0.0 0.9 0.4 4.7 4.9 0.2 1.9 40.1 8.5 6.2 5.0 1.5 2.0 2.3 3.7 0.2 1.2 0.3 1.0 0.5 3.1 0.8 4.4 4.1 5.1 1.3 0.3 2.3 0.3 0.6 0.3 4.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 10.1 4.5 0.0 0.0 3.6 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 20.3 0.2 0.0 0.0 3.3 12.3 0.2 17.4 0.0 0.0 0.0 0.2 0.4 0.8 5.1 0.0 0.0 1.1 0.0 2.0 4.5 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 76.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 5.2 5.8 18.3 5.6 4.4 5.3 4.7 4.9 5.0 3.1 5.1 4.0 22.0 0.0 4.8 92.7 1.6 1.0 0.4 4.1 0.0 8.2 15.6 10.3 4.7 0.0 5.7 3.7 0.0 8.3 10.9 2.0 3.9 8.1 9.9 9.8 2.4 16.7 35.2 13.5 4.7 6.0 0.3 4.0 40.2 26.2 0.0 1.1 0.0 0.0 9.9 0.0 25.6 25.0 6.1 1.9 1.1 4.9 1.5 1.1 7.2 18.7 0.0 2.6 1.0 129.7 0.4 1.6 3.5 1.5 14.0 2.1 0.3 0.0 1.2 1.0 0.0 0.8 2.3 3.8 5.5 0.2 0.4 1.4 0.7 3.1 3.3 1.5 CABP2 DFNB93 ENSG00000167791 "Calcium binding protein 2" Q9NPB3 11 67518912-67524517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "retina: 7.3" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 100.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 9.3" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 56: Bipolar cells - Visual perception" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.2 0.0 0.0 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CCDC28B "MGC1203, RP4-622L5.5" ENSG00000160050 "Coiled-coil domain containing 28B" Q9BUN5 1 32200595-32205453 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 225.3;tongue: 75.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 90.1;monocytes: 65.5;NK-cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 124.9" "Low region specificity" "Detected in all" HPA028589 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA028589: AB_10602175" "prognostic favorable (2.92e-4)" "unprognostic (6.01e-3)" "unprognostic (1.04e-1)" "unprognostic (2.61e-2)" "unprognostic (2.59e-3)" "unprognostic (5.18e-2)" "unprognostic (7.50e-3)" "unprognostic (7.87e-2)" "unprognostic (5.15e-2)" "unprognostic (1.79e-2)" "prognostic favorable (1.10e-5)" "unprognostic (2.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.44e-2)" "unprognostic (1.67e-1)" "unprognostic (7.83e-2)" "unprognostic (1.07e-2)" 3.8 13.9 14.3 7.1 12.9 6.8 3.3 14.5 18.7 6.6 12.1 7.6 1.7 5.3 1.7 5.5 5.6 4.9 20.8 13.2 13.3 6.5 2.4 3.9 14.1 12.8 13.3 6.0 5.6 19.2 21.1 5.0 12.2 5.3 2.5 5.1 3.6 4.1 225.3 2.7 4.3 6.2 12.6 5.4 3.9 20.8 15.8 12.4 6.3 75.0 9.5 5.0 4.3 13.1 10.6 4.5 20.8 22.7 6.8 8.5 1.2 8.2 11.9 13.2 9.3 9.0 13.2 23.3 14.2 9.3 1.7 0.5 18.7 9.2 2.6 27.0 25.5 29.9 20.7 4.1 10.1 0.2 13.7 10.5 3.5 15.5 0.2 9.2 19.3 40.5 20.5 0.5 9.6 1.3 43.2 8.7 29.4 2.8 5.8 46.5 10.4 19.2 12.2 0.0 45.6 22.9 11.9 3.2 16.3 12.0 12.0 11.5 11.4 7.1 9.5 8.7 7.6 2.1 1.6 0.9 11.7 43.9 10.3 9.7 13.7 3.0 36.3 6.9 17.6 22.0 19.4 34.3 30.6 31.5 28.4 29.3 1.9 46.7 2.1 37.1 26.9 21.8 14.3 12.9 14.5 18.7 13.2 13.3 12.8 13.3 12.2 12.6 15.8 13.1 10.5 0.0 6.1 3.9 11.1 9.1 4.4 17.9 5.7 33.3 9.6 12.7 16.1 11.5 5.3 12.9 22.9 1.9 25.8 1.6 35.2 17.5 13.8 8.1 18.1 15.2 90.1 30.7 3.1 7.6 4.0 19.0 5.6 5.1 3.8 8.0 12.1 0.6 11.7 23.5 3.9 5.7 54.9 4.2 39.2 32.8 20.2 5.7 17.8 0.0 65.5 23.9 106.1 5.5 1.7 7.8 1.7 17.0 1.8 3.4 0.3 4.9 4.2 45.9 0.0 12.5 18.0 3.9 13.3 3.5 7.7 2.2 15.3 48.1 3.4 2.6 CD70 "CD27L, CD27LG, TNFSF7" ENSG00000125726 "CD70 molecule" P32970 19 6583183-6604103 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 4 "monocytes: 239.4" "Cancer enriched" "Detected in many" 4 "renal cancer: 24.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 44.2" "Group enriched" "Detected in many" 35 "B-cells: 24.2;T-cells: 44.2" "Cell line enhanced" "Detected in many" "SiHa: 189.2;THP-1: 157.3;U-251 MG: 234.2;U-266/70: 399.5;U-266/84: 312.7;U-698: 138.1" "Region enriched" "Detected in single" 25 "cerebellum: 11.3" "Low region specificity" "Detected in all" HPA046582 Uncertain Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA046582: " "unprognostic (8.71e-2)" "unprognostic (9.91e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-4)" "unprognostic (1.73e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.57e-2)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" 2.4 0.1 0.1 3.2 0.1 0.8 1.1 0.5 0.3 0.4 0.3 2.2 0.5 0.1 0.0 0.7 0.2 0.4 0.1 0.1 0.2 0.5 0.2 0.8 3.4 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.2 0.2 1.5 0.0 0.2 0.0 0.3 1.4 2.2 0.1 0.0 2.9 1.0 0.3 0.1 1.5 0.3 0.9 1.9 1.1 0.5 0.4 1.3 39.1 0.1 75.6 1.7 1.0 0.1 0.0 0.3 0.3 2.6 0.1 0.5 74.2 4.1 0.4 81.8 53.2 46.5 3.6 0.0 0.2 1.6 0.0 56.8 0.1 0.0 0.0 2.2 0.5 0.4 43.9 31.1 12.2 0.3 0.1 1.3 2.5 1.1 0.2 1.3 94.3 0.9 0.0 70.0 20.3 0.1 16.3 24.6 0.2 0.0 0.0 189.2 0.0 0.8 0.2 0.5 157.3 1.0 0.6 32.6 0.0 234.2 399.5 312.7 138.1 41.0 23.8 14.8 0.8 0.1 0.1 3.3 0.0 8.1 24.2 5.3 8.8 0.1 9.9 0.7 2.1 0.2 0.9 0.0 0.3 44.2 1.6 0.1 0.1 0.5 0.3 0.1 0.2 0.2 0.2 0.2 0.0 0.1 0.4 0.6 0.0 0.0 0.0 50.9 5.7 0.1 11.1 0.0 0.0 0.1 0.3 0.2 0.0 0.3 1.8 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.4 0.0 1.6 1.8 0.0 0.1 0.7 0.0 11.3 0.5 0.2 1.3 0.1 0.7 0.3 0.4 0.0 0.7 0.0 18.3 0.6 14.6 0.0 0.0 3.0 3.6 0.0 239.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 24.9 0.2 0.0 0.2 0.7 0.0 0.0 0.4 0.9 0.2 0.6 0.4 5.4 0.0 14.1 0.0 0.4 0.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.8;Gastric mucus-secreting cells: 23.0;Paneth cells: 18.3;Squamous epithelial cells: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.3;HaCaT: 22.5;MCF7: 30.7;RT4: 18.4;SK-BR-3: 18.4;T-47d: 18.1" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 4.9 0.2 1.4 0.3 2.1 4.8 9.7 1.2 5.4 5.5 8.8 10.6 0.4 2.0 26.5 3.8 2.8 0.4 0.4 0.3 7.7 0.9 7.8 1.3 0.4 0.7 2.2 14.1 6.4 11.0 4.2 1.0 8.5 4.5 0.3 17.7 3.7 0.2 33.7 9.3 0.2 0.3 1.8 12.2 3.3 0.3 2.4 6.0 0.0 2.0 5.8 13.0 0.3 8.9 1.2 0.8 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 11.7 7.5 0.1 4.3 0.0 0.4 22.5 1.3 8.8 0.0 0.4 3.6 0.7 5.3 3.8 0.0 0.3 2.2 0.0 10.9 0.1 0.1 0.1 0.1 3.5 6.1 0.1 0.0 30.7 0.2 1.7 2.7 8.3 1.3 1.3 0.5 4.3 5.5 18.4 15.6 0.7 2.8 18.4 0.5 4.3 18.1 0.4 0.1 0.0 3.1 0.1 0.1 2.1 2.2 2.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 9.7 1.2 0.4 0.3 0.4 0.7 1.0 0.3 0.3 0.3 1.0 9.6 7.9 0.0 1.2 6.5 2.3 3.6 9.6 0.0 5.1 5.8 1.8 2.8 9.6 1.8 0.0 6.4 1.7 14.8 0.0 2.4 0.6 13.2 0.7 0.4 3.6 0.8 0.1 6.2 4.9 0.7 23.0 7.9 1.3 0.4 0.0 0.0 1.0 0.0 0.1 4.8 2.0 0.0 0.4 0.8 0.0 1.3 0.0 0.0 1.2 0.8 1.0 0.0 0.1 2.9 18.3 0.0 0.1 1.6 12.4 0.5 9.5 0.0 0.0 2.2 0.8 1.7 1.3 19.3 8.1 6.7 1.4 0.6 5.7 3.4 CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 24.4;skeletal muscle: 57.0" "Cell type enriched" "Detected in some" 13 "Skeletal myocytes: 76.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 15 "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 145.8" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 17 "cerebellum: 18.7" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" 0.0 0.2 0.1 0.0 0.2 0.0 0.0 24.4 0.8 1.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 1.3 0.4 0.0 0.1 0.8 0.2 1.4 0.0 0.1 0.7 1.6 0.4 0.0 0.0 0.9 0.0 57.0 0.1 0.0 0.0 0.3 1.2 0.2 0.6 0.1 0.0 0.0 5.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.7 0.0 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 31.5 0.1 0.0 0.1 0.0 0.2 0.3 0.0 145.8 0.3 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 24.4 0.8 0.0 0.1 0.1 0.8 1.6 0.3 0.1 0.6 0.2 0.0 2.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 1.0 0.1 1.2 0.0 0.1 0.0 0.3 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.0 76.1 0.4 1.5 5.5 0.0 0.0 0.1 0.2 0.8 0.1 0.1 CEP72 "FLJ10565, KIAA1519" ENSG00000112877 "Centrosomal protein 72" Q9P209 5 612340-667168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.3" "Cell type enriched" "Detected in many" 4 "Melanocytes: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 4.5" "Group enriched" "Detected in many" 4 "B-cells: 1.6;NK-cells: 4.5;T-cells: 1.7" "Cell line enhanced" "Detected in many" "HDLM-2: 46.0;HeLa: 40.0" "Region enriched" "Detected in many" 8 "cerebellum: 14.1" "Not detected" "Not detected" "HPA058235, HPA074879" Approved Approved Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Nucleoplasm, Mitochondria" "HPA058235: AB_2683649, HPA074879: AB_2686720" "unprognostic (2.06e-1)" "unprognostic (3.15e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (8.50e-2)" "unprognostic (9.74e-2)" "unprognostic (2.94e-3)" "unprognostic (3.20e-1)" "unprognostic (1.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.38e-2)" "unprognostic (4.38e-3)" "unprognostic (1.81e-3)" "unprognostic (3.60e-2)" "unprognostic (2.93e-1)" "unprognostic (4.68e-2)" "unprognostic (1.24e-2)" 1.1 0.9 1.3 1.9 1.2 3.1 1.4 1.5 1.3 1.6 0.8 1.2 1.4 1.3 1.0 2.2 1.6 1.5 0.9 1.4 0.6 1.4 2.1 1.4 2.7 0.7 0.8 2.8 1.9 1.2 1.5 0.7 0.8 1.3 0.8 1.1 1.7 0.8 0.7 2.4 1.6 0.9 0.6 1.8 1.8 7.3 0.9 3.0 1.8 0.6 1.4 1.2 1.7 1.8 7.5 11.9 10.6 15.0 0.9 1.0 19.1 3.2 1.4 7.1 6.2 10.8 11.2 8.8 8.2 1.4 13.2 7.1 7.5 5.4 2.8 46.0 11.8 9.7 40.0 4.3 1.3 11.3 6.3 1.1 2.3 6.1 4.1 1.4 2.8 17.0 10.1 10.1 3.5 5.7 17.1 9.8 7.0 6.4 11.1 12.8 6.1 12.2 2.3 5.8 8.1 6.2 23.3 7.6 2.0 3.3 7.6 8.7 0.9 6.8 9.9 6.5 4.6 6.3 6.4 8.8 4.2 15.7 7.3 0.0 0.3 0.3 1.3 0.1 1.7 1.4 1.1 1.2 0.1 1.6 1.6 1.6 0.0 4.5 0.6 0.4 1.5 0.8 1.3 1.2 1.5 1.3 1.4 0.6 0.7 0.8 0.8 0.6 0.9 1.8 0.7 3.2 1.5 1.3 2.9 5.7 0.9 2.4 0.6 2.5 1.1 1.8 2.2 2.8 1.0 0.0 0.0 1.2 1.1 1.1 0.0 2.5 4.0 2.4 1.5 1.1 0.0 4.2 2.5 0.9 5.1 1.0 3.6 1.9 0.0 3.8 0.4 1.7 1.4 3.3 1.3 0.7 4.1 0.8 2.9 2.2 1.2 0.7 135.2 1.0 1.4 0.9 2.1 2.0 3.9 2.3 0.5 2.6 4.7 1.1 0.1 0.5 3.4 2.0 0.0 1.3 1.1 30.7 10.1 2.8 3.7 1.6 1.9 0.9 1.3 2.5 CEP76 "C18orf9, FLJ12542, HsT1705" ENSG00000101624 "Centrosomal protein 76" Q8TAP6 18 12661833-12702777 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 209.7;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 60.5" "Region enriched" "Detected in all" 9 "cerebellum: 55.0" "Region enriched" "Detected in all" 5 "cerebellum: 16.3" HPA039395 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039395: AB_10673357" "unprognostic (3.39e-1)" "unprognostic (2.99e-2)" "unprognostic (2.26e-1)" "unprognostic (9.31e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.00e-4)" "unprognostic (7.88e-3)" "unprognostic (2.45e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-2)" "unprognostic (4.39e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-2)" "unprognostic (8.21e-2)" 3.0 3.4 2.5 2.6 2.5 6.2 3.8 7.7 3.3 3.4 2.6 2.9 2.7 3.3 5.1 5.3 2.7 2.6 2.7 2.3 2.5 3.1 4.8 2.7 3.8 2.3 2.4 3.2 2.3 2.5 2.2 3.4 2.5 2.8 3.9 4.5 2.9 2.8 3.2 4.0 3.1 3.3 2.3 2.5 2.8 8.2 2.6 7.9 3.7 3.5 4.7 3.2 2.8 2.6 7.3 7.2 12.1 5.9 7.1 3.8 11.7 8.4 9.4 16.1 12.5 16.6 8.5 9.7 7.3 5.5 9.4 5.6 12.1 5.3 13.7 6.1 9.8 8.5 8.0 14.1 5.3 20.0 9.5 3.0 5.3 9.5 6.2 4.5 8.5 13.5 14.5 14.3 10.4 5.5 17.5 13.9 8.7 60.5 4.7 12.2 10.5 10.4 8.4 7.1 9.2 8.0 10.5 6.7 6.9 7.9 4.8 11.0 8.0 10.8 21.9 10.6 10.0 8.0 14.8 11.5 5.4 9.7 7.2 0.4 2.3 2.1 2.6 4.4 3.5 1.8 2.9 3.2 2.1 2.3 2.9 3.4 0.7 3.7 1.7 1.2 3.5 2.2 2.5 2.5 7.7 3.3 2.3 2.5 2.3 2.4 2.5 2.3 2.6 2.6 4.3 6.4 5.9 7.5 7.2 9.7 3.9 3.0 5.2 6.3 4.1 4.6 1.8 1.5 5.4 0.0 12.5 5.9 6.7 3.7 1.9 3.0 209.7 5.5 5.8 5.2 6.0 13.9 16.9 2.5 7.5 4.0 2.0 4.6 5.7 14.0 4.2 4.8 4.1 3.3 16.7 5.5 4.1 3.5 4.1 57.8 3.7 3.4 7.2 3.7 2.5 2.9 6.2 7.5 7.9 3.8 0.6 4.5 10.3 5.1 7.8 2.5 3.5 8.0 6.6 7.1 3.7 27.7 22.1 12.4 8.2 6.2 6.4 11.5 4.8 5.7 CNPY1 ENSG00000146910 "Canopy FGF signaling regulator 1" Q3B7I2 7 155474206-155555450 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 23.4" "Group enriched" "Detected in some" 6 "Astrocytes: 2.6;Oligodendrocytes: 2.0;Spermatocytes: 2.3;Spermatogonia: 6.3" "Cancer enriched" "Detected in single" 10 "glioma: 1.6" "Group enriched" "Detected in many" 6 "cerebellum: 23.4;midbrain: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AF22: 30.7" "Region enriched" "Detected in some" 29 "cerebellum: 192.3" "Region enriched" "Detected in some" 10 "cerebellum: 58.6" HPA047400 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA047400: AB_10960413" "unprognostic (4.28e-3)" "unprognostic (2.12e-1)" "unprognostic (4.18e-2)" "unprognostic (8.27e-12)" "unprognostic (1.44e-1)" "unprognostic (2.16e-1)" 0.1 0.1 0.4 0.1 0.7 0.4 0.0 23.4 1.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 0.0 0.1 0.2 0.7 6.6 0.1 3.6 0.0 0.1 0.0 2.5 0.0 0.1 1.1 0.2 0.0 0.0 0.5 0.3 0.0 0.4 0.0 0.1 0.9 0.6 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.0 30.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 2.7 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3.9 0.0 0.0 0.2 0.1 0.0 0.1 0.8 0.2 0.1 0.6 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 23.4 1.1 0.5 0.3 0.7 6.6 2.5 0.4 0.6 1.9 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 CPSF4L ENSG00000187959 "Cleavage and polyadenylation specific factor 4 like" A6NMK7 17 73248449-73262352 "Predicted intracellular proteins" RNA-binding "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Skeletal myocytes: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 3.0" "Region enriched" "Detected in single" 36 "cerebellum: 10.2" "Low region specificity" "Detected in many" HPA044047 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "HPA044047: AB_10961638" "unprognostic (7.30e-2)" "unprognostic (1.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" "unprognostic (1.99e-1)" "unprognostic (7.73e-2)" "unprognostic (2.32e-2)" "unprognostic (5.59e-2)" "unprognostic (6.57e-3)" "unprognostic (9.76e-2)" "unprognostic (1.83e-1)" "unprognostic (3.66e-2)" "unprognostic (9.03e-8)" "unprognostic (6.71e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-2)" "unprognostic (7.44e-3)" 0.1 0.1 0.1 0.0 0.1 0.0 0.4 0.9 0.5 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.9 0.5 0.2 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Group enriched" "Detected in some" 4 "dendritic cells: 63.8;Plasma cells: 16.0;T-cells: 54.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Cell line enriched" "Detected in single" 34 "SCLC-21H: 12.9" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" 0.3 0.3 0.3 2.3 0.5 1.8 0.5 38.2 1.4 0.3 0.3 0.5 0.6 0.8 0.5 0.3 0.3 1.5 0.2 0.2 0.4 0.1 1.0 1.8 8.8 1.1 1.4 0.3 0.1 0.1 0.1 0.2 4.2 0.3 0.6 0.0 0.7 0.2 0.1 0.3 1.2 0.2 0.5 3.6 0.8 0.2 0.7 4.9 0.2 0.0 3.5 0.8 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 4.6 0.6 13.0 5.6 12.9 0.1 1.5 27.0 3.6 0.2 4.3 33.3 1.2 54.0 10.5 0.2 0.1 6.0 0.3 0.5 38.2 1.4 0.2 0.4 1.1 1.4 4.2 0.5 0.7 1.6 1.1 0.0 1.1 0.3 0.8 1.5 0.4 0.1 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.0 0.1 63.8 0.1 0.0 0.0 1.2 0.4 0.4 0.3 0.0 0.4 0.5 0.0 0.2 1.6 2.0 0.6 1.3 0.0 0.4 0.2 5.9 0.0 0.7 0.0 0.0 8.8 8.1 1.2 0.0 10.3 3.6 0.0 9.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.3 0.5 0.0 0.9 0.1 54.1 0.0 0.0 0.5 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 EN2 ENSG00000164778 "Engrailed homeobox 2" P19622 7 155458129-155464831 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "brain: 19.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3.6;Glandular and luminal cells: 8.7" "Cancer enhanced" "Detected in many" "melanoma: 6.3" "Group enriched" "Detected in many" 6 "cerebellum: 19.2;midbrain: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.1;AN3-CA: 15.2;HAP1: 9.0;HEK 293: 25.1;SK-MEL-30: 12.9" "Region enriched" "Detected in some" 8 "cerebellum: 27.8" "Region enriched" "Detected in some" 5 "cerebellum: 52.3" "HPA045646, HPA069809" Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "HPA045646: AB_2679404, HPA069809: AB_2686205" "unprognostic (2.44e-3)" "unprognostic (1.71e-2)" "unprognostic (4.89e-2)" "unprognostic (7.99e-3)" "prognostic unfavorable (1.74e-6)" "unprognostic (2.54e-1)" "unprognostic (8.02e-2)" "unprognostic (7.00e-2)" "unprognostic (1.15e-1)" "unprognostic (9.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.94e-1)" "unprognostic (1.03e-13)" "unprognostic (4.91e-3)" "unprognostic (2.72e-1)" "unprognostic (2.24e-1)" "unprognostic (5.64e-3)" 0.1 0.1 0.1 0.0 0.2 0.0 0.1 19.2 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.2 8.0 0.6 0.3 0.5 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.8 0.7 41.1 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 0.0 1.4 0.0 9.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.3 5.5 0.0 0.0 0.0 0.0 2.0 0.0 3.2 0.0 0.1 0.3 0.0 0.0 3.0 0.0 12.9 0.0 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 19.2 0.7 0.2 0.4 0.2 8.0 2.3 0.3 0.9 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 3.6 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 8.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.4 1.5 0.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 FAT2 "CDHF8, CDHR9, HFAT2, MEGF1" ENSG00000086570 "FAT atypical cadherin 2" Q9NYQ8 5 151504093-151568944 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.4;esophagus: 50.9;skin 1: 56.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.0;Basal respiratory cells: 31.6;Basal squamous epithelial cells: 27.9;Early spermatids: 16.0;Extravillous trophoblasts: 20.6;Squamous epithelial cells: 53.2;Suprabasal keratinocytes: 19.6" "Group enriched" "Detected in many" 6 "cervical cancer: 13.9;head and neck cancer: 21.4;lung cancer: 6.1;urothelial cancer: 5.6" "Region enriched" "Detected in many" 7 "cerebellum: 113.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 35.1;EFO-21: 21.0;HaCaT: 51.7;HBEC3-KT: 23.6;hTCEpi: 70.5" "Region enriched" "Detected in some" 18 "cerebellum: 32.0" "Region enriched" "Detected in many" 56 "cerebellum: 224.4" CAB033680 Enhanced NA NA 300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB033680: AB_2100956" "unprognostic (8.06e-3)" "unprognostic (6.01e-2)" "unprognostic (3.47e-1)" "unprognostic (4.80e-3)" "unprognostic (1.33e-1)" "unprognostic (4.43e-1)" "unprognostic (9.78e-3)" "unprognostic (2.28e-1)" "unprognostic (8.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-7)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (6.77e-2)" "unprognostic (3.64e-3)" 0.4 0.2 0.4 0.0 3.8 0.1 3.6 113.4 4.8 11.5 0.0 0.1 0.1 0.1 1.7 50.9 1.0 0.0 0.1 0.5 0.4 0.6 0.1 0.2 0.0 15.1 2.8 0.1 0.2 0.2 0.5 0.9 17.2 5.3 0.0 0.1 8.9 4.8 0.2 56.0 0.2 0.0 0.4 0.1 0.1 13.2 0.5 2.2 0.1 0.0 3.4 2.9 24.4 2.2 1.7 0.0 0.0 0.1 0.0 0.0 35.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 21.0 0.0 0.2 51.7 0.0 23.6 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 70.5 0.0 3.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.7 0.1 0.0 0.1 1.1 0.2 0.5 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.8 113.4 4.8 0.5 0.4 15.1 2.8 17.2 0.4 0.5 2.2 0.1 0.0 0.0 0.7 0.0 18.0 5.8 31.6 27.9 0.0 3.4 12.8 1.9 0.0 11.1 1.8 0.0 0.4 0.0 0.0 0.0 0.0 16.0 0.1 0.0 0.3 0.0 0.0 5.0 0.0 20.6 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.0 1.5 7.8 0.0 0.0 7.2 0.0 0.0 0.0 0.0 4.0 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.1 3.0 0.0 0.0 0.0 0.4 0.5 0.1 53.2 19.6 1.0 0.1 0.0 0.0 13.0 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 GABRA6 ENSG00000145863 "Gamma-aminobutyric acid type A receptor subunit alpha6" Q16445 5 161547063-161702593 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "brain: 71.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 14 "cerebellum: 71.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 40 "cerebellum: 1073.8" "Region enriched" "Detected in some" 37 "cerebellum: 262.3" CAB022462 Approved NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022462: " "unprognostic (3.79e-2)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 71.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 71.1 2.8 0.1 0.3 0.2 1.8 4.9 0.4 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960754-42963880 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "liver: 296.5;pancreas: 600.1" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 842.9" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;SCLC-21H: 9.5;T-47d: 6.1" "Region enriched" "Detected in some" 4 "cerebellum: 15.7" "Low region specificity" "Detected in many" HPA027501 Enhanced Approved Cytosol NA NA 390000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favorable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.9 0.9 2.3 1.3 2.5 3.8 7.1 2.8 2.4 0.8 2.0 0.7 0.2 0.8 2.2 0.6 1.3 0.5 4.7 2.2 2.2 0.9 296.5 2.0 1.0 1.1 1.0 1.9 600.1 0.2 8.4 0.4 1.1 20.3 0.3 2.2 9.8 1.2 1.8 0.9 1.6 0.5 0.9 2.9 50.8 0.7 1.9 1.8 1.9 0.4 1.2 0.8 0.7 2.1 0.4 0.3 1.4 3.9 0.4 0.1 0.2 0.3 1.6 0.6 0.9 0.0 0.1 1.3 0.1 0.3 0.7 0.4 0.2 0.2 0.2 1.6 1.2 1.0 0.9 8.5 0.0 0.9 1.8 0.3 0.0 0.3 0.1 0.9 0.0 3.0 1.2 1.5 0.2 1.8 1.6 3.0 0.1 0.4 0.4 1.4 1.3 0.8 0.6 0.2 9.5 1.3 0.1 1.3 0.6 0.4 6.1 2.8 0.3 0.7 0.7 0.4 0.8 1.0 1.0 1.1 0.1 1.6 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.0 0.7 0.0 0.1 2.3 2.5 2.8 2.4 2.2 2.2 1.1 1.0 1.1 0.9 1.9 2.1 0.3 0.0 2.2 5.5 2.8 0.3 5.2 0.7 0.0 1.7 10.2 14.7 5.4 24.3 0.2 1.8 0.0 0.1 1.7 0.0 3.9 0.5 0.2 1.6 0.2 2.2 0.0 77.9 18.4 0.9 0.1 0.3 0.5 0.8 0.0 2.6 24.3 842.9 0.7 1.7 18.2 0.0 6.1 28.9 0.7 0.1 0.9 1.1 0.0 11.2 0.3 0.2 0.0 7.1 4.7 0.6 0.0 2.6 0.5 17.9 0.3 3.4 4.6 0.3 0.0 0.2 0.6 0.6 0.7 0.0 0.1 0.1 3.0 0.0 0.2 1.9 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 HES3 bHLHb43 ENSG00000173673 "Hes family bHLH transcription factor 3" Q5TGS1 1 6244179-6245578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "NTERA-2: 11.0" "Region enriched" "Detected in some" 30 "cerebellum: 34.8" "Low region specificity" "Detected in some" "HPA047927, HPA072697" Uncertain Approved Nucleoplasm NA NA "Cluster 5: NTERA-2 - Transcription" Nucleoplasm "HPA047927: AB_2680213, HPA072697: " "unprognostic (7.42e-2)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.2 0.2 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" 22.6 23.0 12.4 13.6 18.1 4.0 15.8 18.2 13.1 20.3 17.7 20.9 19.6 20.1 20.9 21.6 16.2 13.1 27.1 12.5 12.9 25.9 13.6 14.9 10.2 12.6 14.9 9.1 17.4 26.8 22.0 21.0 12.7 17.3 17.4 28.7 17.1 18.9 53.0 19.2 18.3 21.9 12.3 9.1 15.7 5.2 14.5 14.9 18.1 82.6 11.0 17.4 16.0 12.0 35.8 32.6 43.7 43.0 131.2 51.8 18.7 84.9 56.1 48.7 36.9 35.0 28.2 39.0 31.7 66.7 42.0 47.4 50.5 35.6 51.5 78.8 51.3 26.8 46.0 26.8 25.5 42.5 36.4 33.3 23.5 51.2 19.2 32.4 38.5 31.6 26.5 29.8 55.7 22.3 43.2 29.6 29.7 64.1 46.0 35.8 61.5 22.6 59.3 25.8 59.2 28.8 41.3 96.3 37.2 48.4 25.2 35.4 48.1 55.3 21.7 65.4 61.6 27.7 57.8 30.5 27.1 96.5 29.3 2.6 1.9 1.6 3.1 2.2 2.7 1.1 2.5 3.1 1.7 1.8 2.1 1.8 0.6 1.8 1.9 2.7 1.4 1.9 12.4 18.1 18.2 13.1 12.5 12.9 12.6 14.9 12.7 12.3 14.5 12.0 18.0 22.4 12.1 5.9 7.7 6.2 9.6 12.2 7.4 18.0 16.3 9.8 39.3 15.7 19.6 29.5 31.3 57.6 12.3 40.7 13.7 21.9 3.5 19.5 18.8 18.1 22.8 14.9 10.2 22.2 85.7 19.6 12.8 16.9 5.1 13.9 21.8 23.9 29.1 48.8 9.4 21.4 12.2 12.0 7.0 5.1 20.8 9.8 7.2 7.5 12.1 18.9 10.3 2.0 5.4 26.8 12.2 26.4 18.3 14.1 45.5 36.9 41.7 58.8 13.1 9.9 22.1 15.4 26.8 28.2 10.4 32.0 10.4 13.9 23.1 14.7 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT28 KRT25D ENSG00000173908 "Keratin 28" Q7Z3Y7 17 40792196-40799959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 11.7" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.3" "Cancer enhanced" "Detected in some" "cervical cancer: 0.6;endometrial cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.2" "Not detected" "Not detected" HPA066890 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 25: Spermatids - Spermatogenesis" "HPA066890: AB_2685742" 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LDOC1 "BCUR1, Mar7, Mart7, RTL7, SIRH7" ENSG00000182195 "LDOC1 regulator of NFKB signaling" O95751 X 141111605-141177129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 123.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 24.7;MCF7: 31.9;PC-3: 34.3;U-251 MG: 21.9" "Region enriched" "Detected in many" 5 "cerebellum: 19.2" "HPA051768, HPA061842" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA051768: AB_2681599, HPA061842: AB_2684624" "unprognostic (4.09e-1)" "unprognostic (4.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.42e-1)" "unprognostic (4.51e-2)" "unprognostic (2.08e-2)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (6.40e-3)" "unprognostic (1.21e-1)" "unprognostic (1.27e-2)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-3)" "unprognostic (2.76e-2)" 32.3 34.0 4.7 0.9 5.5 0.1 28.0 2.9 8.5 45.8 0.2 18.8 0.9 53.9 1.8 21.4 48.5 1.6 15.1 6.2 5.8 33.2 4.8 19.6 0.8 5.3 5.0 46.8 19.3 10.5 123.3 0.0 5.0 34.3 0.3 3.4 55.1 5.9 5.5 31.5 12.5 2.0 1.2 14.2 18.4 10.8 5.0 0.9 53.7 0.4 0.7 33.1 30.6 6.0 0.0 24.7 3.0 8.4 5.0 6.2 0.0 5.0 5.8 6.3 8.8 0.0 8.0 0.0 4.2 7.7 6.1 10.4 3.4 7.1 4.5 0.0 6.6 0.0 11.7 0.0 2.0 0.0 1.9 10.9 3.6 5.5 2.9 5.1 5.7 0.0 0.1 0.0 5.7 31.9 0.0 0.0 3.3 0.0 34.3 0.0 2.7 0.0 7.7 4.7 0.0 3.2 0.0 4.0 0.0 1.6 5.1 0.0 11.9 0.0 6.8 0.0 21.9 0.0 0.0 0.0 3.5 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.8 0.9 2.5 0.8 0.2 2.1 2.2 1.4 0.0 6.4 0.0 1.4 2.6 1.0 4.7 5.5 2.9 8.5 6.2 5.8 5.3 5.0 5.0 1.2 5.0 6.0 8.6 0.0 5.3 4.2 4.9 6.0 16.8 4.6 16.5 29.3 23.8 20.2 2.2 30.0 8.2 23.9 8.4 2.8 5.7 0.1 43.0 13.8 0.7 7.8 13.5 12.8 5.4 0.8 9.4 14.0 1.8 16.1 3.6 6.0 2.5 8.8 12.8 0.1 0.9 20.2 9.9 0.4 8.2 0.3 1.8 1.1 22.1 1.0 3.6 7.5 0.3 21.2 5.2 7.1 15.0 13.7 0.2 38.7 0.9 11.9 0.0 43.8 4.6 13.0 13.1 15.3 26.2 0.9 7.6 16.7 6.8 1.5 5.2 13.5 0.3 15.0 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MDFI I-mfa ENSG00000112559 "MyoD family inhibitor" Q99750 6 41636882-41654244 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 221.7;Extravillous trophoblasts: 113.7;Pancreatic endocrine cells: 134.9;Syncytiotrophoblasts: 138.7;Urothelial cells: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 80.5;HBEC3-KT: 117.2;OE19: 100.0;REH: 315.3" "Region enriched" "Detected in many" 7 "cerebellum: 17.0" "Low region specificity" "Detected in all" HPA049973 Approved Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA049973: AB_2680975" "unprognostic (9.74e-3)" "unprognostic (4.25e-2)" "unprognostic (6.82e-2)" "unprognostic (6.26e-3)" "unprognostic (9.18e-2)" "unprognostic (1.07e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.32e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.66e-1)" "unprognostic (3.27e-2)" "unprognostic (4.04e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.66e-2)" "unprognostic (6.06e-2)" "unprognostic (1.57e-1)" "unprognostic (8.22e-2)" 33.0 4.3 3.9 5.7 4.2 0.2 23.1 4.1 5.8 23.2 4.3 2.5 1.7 5.8 1.2 44.7 10.0 12.8 8.8 3.5 4.3 5.5 1.5 18.6 1.7 8.2 5.8 15.6 3.2 1.6 9.1 11.0 6.3 14.3 0.4 0.1 22.4 2.2 0.9 15.4 3.2 2.5 3.6 0.3 4.6 5.0 4.6 1.5 4.6 1.1 2.5 13.6 27.1 4.2 60.1 0.2 50.4 0.1 0.1 0.0 80.5 0.0 0.0 0.0 0.0 0.0 28.2 0.1 18.2 0.0 0.3 48.4 13.8 117.2 0.0 0.0 0.0 0.4 0.0 2.5 2.2 0.0 0.3 3.6 53.3 0.6 24.6 0.0 38.4 16.1 0.2 0.3 0.0 0.0 41.8 0.4 34.4 100.0 1.6 315.3 29.6 0.5 3.3 9.2 9.4 23.2 0.6 43.1 0.0 34.5 0.2 4.0 40.3 0.1 44.1 0.5 1.7 0.1 0.3 0.1 0.3 2.8 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.2 4.1 5.8 3.5 4.3 8.2 5.8 6.3 3.6 4.6 4.2 1.8 0.0 0.0 0.0 0.0 24.5 48.6 36.8 12.0 0.5 18.9 16.9 0.9 0.0 8.2 5.5 0.0 221.7 0.2 0.4 0.0 33.8 0.5 0.5 1.7 12.7 0.0 0.0 0.1 51.2 113.7 12.8 0.0 0.7 0.0 10.0 7.9 0.1 19.6 0.0 0.3 1.2 6.1 0.0 4.5 0.5 39.1 0.4 0.0 2.8 0.6 0.0 0.0 4.5 0.2 134.9 0.0 6.0 0.0 55.6 0.0 0.0 3.5 0.0 0.0 19.7 9.1 0.1 7.9 10.7 9.1 138.7 0.6 2.7 0.3 73.5 MEGF11 "DKFZp434L121, KIAA1781" ENSG00000157890 "Multiple EGF like domains 11" A6BM72 15 65895079-66253747 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.0;fallopian tube: 7.8;kidney: 8.4;retina: 14.2" "Group enriched" "Detected in many" 9 "Early spermatids: 175.8;Horizontal cells: 126.2;Late spermatids: 177.8;Oligodendrocyte precursor cells: 460.4" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.7;glioma: 2.3;renal cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.3;HEK 293: 2.7;RPTEC TERT1: 9.2;SCLC-21H: 7.2;U-698: 2.0" "Region enriched" "Detected in all" 4 "cerebellum: 35.0" "Region enriched" "Detected in all" 7 "cerebellum: 25.8" NA NA "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.97e-2)" "unprognostic (1.23e-1)" "unprognostic (7.95e-2)" "unprognostic (1.84e-2)" "unprognostic (9.02e-3)" "unprognostic (6.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.08e-2)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" "unprognostic (6.79e-3)" "unprognostic (6.81e-3)" "unprognostic (5.71e-5)" "unprognostic (7.94e-2)" "unprognostic (9.78e-3)" "unprognostic (2.03e-1)" "unprognostic (4.89e-2)" 0.0 0.1 8.3 0.2 5.3 0.3 0.1 23.0 7.0 0.1 0.4 0.1 0.0 0.1 0.8 0.1 7.8 0.0 0.1 10.5 7.5 8.4 0.0 0.5 0.1 6.6 8.8 0.3 0.2 0.0 3.0 0.0 7.0 0.1 0.0 14.2 0.1 0.1 0.1 1.3 0.1 0.0 4.5 0.2 0.3 3.9 8.0 0.1 0.0 0.0 0.0 0.0 0.1 7.4 0.0 0.1 0.3 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.2 0.0 0.1 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 0.0 0.0 9.2 0.2 7.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 5.3 23.0 7.0 10.5 7.5 6.6 8.8 7.0 4.5 8.0 7.4 0.2 0.0 3.7 5.2 0.4 2.2 0.7 1.0 0.6 5.3 0.8 0.0 1.4 0.0 0.3 3.7 8.4 0.3 0.4 0.0 0.0 0.1 175.8 0.3 0.3 1.5 0.0 0.4 9.5 0.2 0.1 0.7 2.6 0.8 0.0 0.2 2.9 0.0 0.1 126.2 18.4 0.0 0.0 0.3 3.5 177.8 2.5 0.4 0.0 1.0 0.0 4.4 0.0 460.4 1.7 0.1 0.1 1.5 1.3 0.6 0.0 2.2 0.8 25.7 0.0 1.0 0.5 2.9 1.9 0.6 3.8 0.5 0.9 0.1 0.0 0.5 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MRLN "Linc-RAM, LINC00948, M1, MLN, MUSER1" ENSG00000227877 Myoregulin P0DMT0 10 59736692-59756041 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "skeletal muscle: 269.3;tongue: 147.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 118.8;Proximal tubular cells: 25.8;Respiratory ciliated cells: 35.7;Rod photoreceptor cells: 37.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enriched" "Detected in some" 4 "cerebellum: 4.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "RH-30: 13.3" "Region enriched" "Detected in many" 11 "cerebellum: 21.6" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.32e-2)" "unprognostic (1.52e-1)" "unprognostic (2.27e-1)" "unprognostic (4.54e-1)" "unprognostic (3.17e-3)" "unprognostic (9.77e-2)" "unprognostic (1.09e-2)" "unprognostic (8.49e-2)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (6.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" 0.1 0.2 0.4 0.1 0.4 0.3 0.2 4.5 0.7 0.5 0.4 0.2 1.0 0.5 0.8 1.2 5.1 0.7 0.1 0.4 0.2 8.1 0.2 0.7 0.1 0.5 0.3 0.3 2.8 0.0 12.0 0.1 1.0 1.3 0.1 30.6 7.0 0.1 269.3 0.6 1.1 0.1 0.1 0.5 1.0 0.8 0.3 0.3 0.3 147.3 0.1 0.0 0.1 0.6 0.0 0.8 0.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.6 1.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.7 0.2 1.8 1.1 0.1 0.0 0.6 1.0 0.0 0.6 0.0 0.1 0.0 0.1 0.1 1.0 0.0 1.1 0.0 1.0 0.2 0.2 0.8 0.5 13.3 0.0 0.0 0.2 0.6 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.3 0.6 0.2 0.5 0.1 0.1 0.4 0.3 0.0 1.7 0.3 0.4 0.6 0.1 0.4 0.5 0.3 0.3 0.2 0.6 0.2 0.5 1.2 0.3 0.3 0.4 0.3 0.0 0.4 0.4 4.5 0.7 0.4 0.2 0.5 0.3 1.0 0.1 0.3 0.6 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.1 1.0 0.0 1.8 0.0 2.1 0.0 0.1 1.5 0.0 0.2 5.6 118.8 0.8 0.7 0.0 0.0 1.3 0.2 6.4 0.4 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.5 0.6 0.3 0.0 0.4 0.0 0.1 0.0 25.8 35.7 37.8 0.0 10.1 0.2 2.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.8;intestine: 41.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 220.6;Intestinal goblet cells: 114.2;Paneth cells: 157.1;Proximal enterocytes: 360.1;Undifferentiated cells: 129.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.3;CAPAN-2: 2.4;MCF7: 1.6;OE19: 3.7" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" 1.0 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 9.4 41.7 0.0 0.0 0.0 0.0 13.8 3.2 0.0 0.8 0.2 8.7 0.2 0.3 0.0 0.3 0.0 0.5 0.8 0.0 0.0 0.0 3.1 11.9 0.0 0.1 0.0 5.0 0.1 33.5 0.8 0.0 0.1 2.7 0.1 0.1 9.9 0.8 0.5 0.3 0.4 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 7.3 2.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.6 0.0 0.0 1.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 27.2 0.0 0.0 0.0 1.0 0.4 2.1 28.6 0.0 1.8 0.0 0.7 0.0 220.6 0.0 18.8 0.8 0.0 0.1 0.8 10.3 0.0 0.1 28.8 1.1 0.4 15.8 0.0 0.0 0.0 0.4 5.3 0.3 0.0 0.0 114.2 0.0 0.8 0.0 0.4 0.3 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 28.9 157.1 0.0 0.0 65.7 360.1 0.3 0.0 0.0 0.0 0.4 6.4 0.8 6.8 0.0 0.1 0.3 0.4 0.0 129.5 21.3 MYBPC3 "CMH4, cMyBP-C, FHC" ENSG00000134571 "Myosin binding protein C3" Q14896 11 47331406-47352702 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 584 "heart muscle: 1725.4" "Cell type enriched" "Detected in some" 42 "Cardiomyocytes: 1876.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "U-937: 6.4" "Region enriched" "Detected in some" 33 "cerebellum: 34.4" "Low region specificity" "Detected in many" "HPA040147, HPA043898" Enhanced NA NA 21000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA040147: AB_2676861, HPA043898: AB_2678720" "unprognostic (1.06e-1)" "unprognostic (1.47e-6)" "unprognostic (2.17e-1)" "unprognostic (6.16e-2)" "unprognostic (3.00e-3)" "unprognostic (1.40e-4)" "unprognostic (7.47e-2)" "unprognostic (2.72e-2)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (9.53e-2)" "unprognostic (4.22e-2)" "unprognostic (1.11e-3)" "unprognostic (2.11e-1)" "unprognostic (1.96e-1)" "unprognostic (4.15e-1)" "unprognostic (3.21e-2)" 0.4 2.9 0.0 0.7 0.0 1.5 0.7 0.2 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 1725.4 0.0 0.0 0.3 0.3 2.0 0.5 0.2 0.1 0.1 0.7 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.6 0.0 0.4 0.2 0.3 0.1 0.0 2.8 2.8 1.4 0.0 0.0 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.9 0.0 1.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1876.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.3 0.0 0.0 14.3 0.0 0.0 0.2 0.0 0.0 43.9 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.2 0.8 0.0 0.8 0.0 19.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.1 0.9 0.0 0.0 0.3 0.0 17.4 0.6 0.0 NEUROD1 "BETA2, BHF-1, bHLHa3, MODY6, NEUROD" ENSG00000162992 "Neuronal differentiation 1" Q13562 2 181673088-181680547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 61.4;retina: 125.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 77.5;Cone photoreceptor cells: 150.1;Enteroendocrine cells: 424.2;Rod photoreceptor cells: 203.7" "Group enriched" "Detected in some" 4 "glioma: 1.9;pancreatic cancer: 4.3" "Region enriched" "Detected in many" 7 "cerebellum: 61.4" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 74 "SCLC-21H: 321.5" "Region enriched" "Detected in all" 14 "cerebellum: 216.2" "Region enriched" "Detected in many" 19 "cerebellum: 217.0" "HPA003278, CAB022450" Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB022450: , HPA003278: AB_1845331" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" "unprognostic (6.92e-3)" "unprognostic (1.27e-1)" 0.0 0.1 3.0 0.1 2.1 0.1 0.0 61.4 7.2 0.0 0.7 1.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.7 0.0 0.0 0.0 0.0 0.9 2.4 0.0 10.2 0.0 0.7 0.0 5.2 0.0 1.4 125.7 0.0 0.0 0.1 0.0 4.7 0.0 0.9 0.0 5.4 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 321.5 4.3 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.1 3.0 2.1 61.4 7.2 9.2 0.7 0.9 2.4 5.2 0.9 0.8 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 77.5 0.0 0.0 0.5 0.0 0.0 0.0 150.1 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.9 424.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.1 23.8 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.0 25.9 0.0 0.0 0.1 1.7 12.6 0.0 0.0 0.2 0.7 0.1 0.0 203.7 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.0 1.4 0.2 NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913975 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.9;liver: 142.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 97.2;Distal tubular cells: 52.8;Exocrine glandular cells: 42.4;Gastric mucus-secreting cells: 90.2;Hepatocytes: 173.4;Proximal enterocytes: 49.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 52.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 33 "Hep G2: 78.2" "Region enriched" "Detected in single" 6 "cerebellum: 1.7" "Not detected" "Not detected" HPA003983 Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Vesicles "HPA003983: " "unprognostic (2.99e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-3)" "unprognostic (9.21e-2)" "unprognostic (8.22e-2)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (2.11e-2)" "unprognostic (6.74e-3)" "unprognostic (1.04e-1)" "unprognostic (2.03e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" 0.0 21.4 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.5 76.9 0.0 0.0 0.0 0.0 10.1 12.9 0.0 0.0 33.8 142.4 2.4 0.0 0.0 0.0 0.0 30.6 1.6 0.3 0.0 0.1 0.0 0.4 0.2 0.0 0.0 2.7 0.0 26.5 0.0 0.0 11.5 26.4 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 78.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.3 2.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 15.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 8.4 97.2 0.7 12.9 0.0 0.0 0.0 0.9 52.8 31.3 0.4 0.1 0.0 0.2 24.4 8.0 0.0 42.4 0.0 0.3 90.2 0.0 0.0 3.0 2.5 173.4 0.1 28.6 0.0 7.6 16.2 3.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 15.2 0.3 0.0 0.2 0.0 49.8 0.1 0.0 0.4 0.0 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.3 0.1 11.0 0.2 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.1;ovary: 32.5;placenta: 24.2" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 79.4;Leydig cells: 113.4;Syncytiotrophoblasts: 67.9;Theca cells: 70.2" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 11 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 58.1;HSkMC: 10.6;RH-30: 12.8;RPTEC TERT1: 34.8;SuSa: 40.5" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 41.6" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 0.8 16.1 0.0 0.9 0.0 0.0 0.7 7.0 0.3 1.8 0.0 1.4 0.1 1.7 4.6 0.6 0.9 10.1 3.5 0.0 0.1 6.2 0.1 0.2 0.0 0.1 0.6 32.5 0.4 0.1 0.3 24.2 0.5 4.9 0.3 0.1 1.1 0.9 0.2 0.1 0.3 1.7 0.1 0.0 0.5 3.3 0.0 0.1 0.2 3.3 0.0 1.0 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 10.6 0.0 0.1 0.0 3.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 12.8 0.0 34.8 0.7 0.0 0.2 0.0 1.8 0.0 40.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.1 0.1 0.6 0.5 0.1 0.0 0.4 3.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 1.2 1.0 4.8 0.0 0.0 0.0 0.0 79.4 0.0 0.2 19.6 0.2 1.3 0.0 3.2 0.7 0.0 0.0 0.9 0.0 10.1 8.9 0.0 0.0 0.0 2.1 0.0 0.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 2.6 113.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 13.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.7 1.6 1.7 0.1 0.0 67.9 0.0 70.2 0.2 0.1 OSTN ENSG00000188729 Osteocrin P61366 3 191199241-191265615 "Predicted secreted proteins" Differentiation "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Early spermatids: 4.2;Excitatory neurons: 1.0;Inhibitory neurons: 5.9;Late spermatids: 1.4;Oligodendrocyte precursor cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.0;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 9 "B-cells: 4.0" "Cell line enriched" "Detected in some" 24 "U-2197: 39.1" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in single" "CAB024997, CAB025649, HPA030878" Uncertain "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB024997: , CAB025649: , HPA030878: AB_2673642" "unprognostic (2.35e-2)" "unprognostic (9.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (8.11e-3)" "unprognostic (2.90e-1)" "unprognostic (1.45e-1)" 0.3 0.1 0.6 0.7 0.9 0.0 0.1 0.1 1.2 1.2 0.2 0.1 0.0 0.1 1.6 0.0 0.7 0.8 0.4 0.8 0.8 0.1 0.6 0.2 0.6 0.5 0.2 0.2 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.1 0.2 0.1 0.8 1.2 0.1 0.0 0.4 0.2 0.3 0.4 0.3 0.1 0.1 1.0 0.0 1.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.1 0.0 1.6 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.9 0.1 1.2 0.8 0.8 0.5 0.2 0.5 0.4 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 345.0;Extravillous trophoblasts: 176.8;Paneth cells: 248.9;Proximal enterocytes: 195.6;Undifferentiated cells: 142.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 151.3;CAPAN-2: 102.6;HaCaT: 199.1;hTCEpi: 126.9;MCF7: 94.9;SK-BR-3: 148.0" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" 1.1 0.1 0.3 3.7 0.2 0.0 9.1 0.2 0.6 50.2 0.1 34.3 31.1 1.4 4.7 294.4 7.5 4.9 0.8 0.3 0.3 4.2 0.8 9.7 0.1 0.6 0.2 0.3 27.4 9.1 15.8 10.9 0.6 19.8 10.2 0.0 52.8 5.0 1.0 223.0 28.6 0.5 0.2 0.2 29.1 0.7 0.3 2.5 12.8 0.1 8.8 9.2 104.3 0.3 151.3 28.8 0.0 0.6 0.1 0.2 60.3 1.2 1.0 3.1 1.6 59.2 102.6 0.1 6.0 1.1 6.4 199.1 0.0 75.1 0.5 0.1 36.9 0.1 18.0 41.7 0.6 0.0 0.3 0.5 126.9 0.5 30.8 0.5 0.5 0.0 45.3 0.9 0.4 94.9 0.5 0.2 0.3 75.6 49.1 0.8 0.3 0.6 1.6 29.9 41.1 0.7 42.7 148.0 0.2 1.8 53.8 0.4 5.4 1.0 5.2 2.7 0.8 0.2 0.4 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.6 0.3 0.3 0.6 0.2 0.6 0.2 0.3 0.3 0.2 16.0 13.0 0.0 1.1 72.1 52.0 56.1 54.7 0.2 27.7 26.5 1.1 11.5 36.8 12.9 0.0 133.8 0.4 345.0 0.0 83.8 0.0 16.1 1.8 1.8 21.7 0.0 0.2 62.9 176.8 2.3 91.3 27.4 13.4 0.4 0.0 0.3 13.2 0.0 0.0 95.1 36.7 0.3 6.5 0.4 0.9 0.9 1.8 0.0 2.0 0.6 0.0 0.0 0.0 140.2 248.9 0.0 0.2 63.5 195.6 0.9 17.9 0.2 0.0 0.0 2.8 0.2 1.7 114.1 88.7 109.7 1.6 0.0 142.9 60.4 PPP1R17 "C7orf16, GSBS" ENSG00000106341 "Protein phosphatase 1 regulatory subunit 17" O96001 7 31687215-31708455 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.6;brain: 18.1" "Group enriched" "Detected in some" 35 "Early spermatids: 42.9;Late spermatids: 112.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Group enriched" "Detected in many" 6 "amygdala: 7.8;cerebellum: 18.1;hypothalamus: 7.8;midbrain: 9.6;thalamus: 15.1" "Immune cell enriched" "Detected in some" 4 "non-classical monocyte: 51.9" "Lineage enriched" "Detected in many" 21 "monocytes: 51.9" "Group enriched" "Detected in some" 180 "NTERA-2: 40.4;SCLC-21H: 124.1" "Region enriched" "Detected in many" 32 "cerebellum: 430.8" "HPA047819, HPA073123" Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" "HPA047819: AB_2680166, HPA073123: AB_2732219" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (6.56e-2)" "unprognostic (5.55e-2)" "unprognostic (2.33e-1)" 0.2 4.6 7.8 0.2 2.0 0.3 0.0 18.1 1.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 7.8 0.0 0.0 0.5 0.0 1.3 9.6 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 124.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.1 0.0 51.9 0.0 0.0 0.8 7.8 2.0 18.1 1.9 0.1 7.8 1.3 9.6 1.8 0.3 15.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 112.7 0.3 2.2 0.0 0.0 0.9 0.0 1.0 0.5 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.4;endometrium 1: 5.5;intestine: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 199.5;Inhibitory neurons: 160.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 5.7;cerebellum: 14.4;cerebral cortex: 6.5;hippocampal formation: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 20.0;RT4: 37.4" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" 0.0 2.2 3.7 1.0 5.7 0.0 0.0 14.4 6.5 0.3 0.0 7.4 3.2 5.5 0.0 0.0 0.1 1.0 0.0 7.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 5.0 2.5 0.0 1.1 0.0 0.0 7.6 2.9 1.5 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 37.4 0.1 5.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.7 14.4 6.5 7.2 0.5 0.2 0.0 0.1 1.5 0.0 1.5 1.7 0.0 0.0 3.9 0.2 0.5 0.1 0.5 0.0 16.5 0.2 0.1 3.5 0.0 3.4 0.0 0.0 0.0 0.7 43.2 0.0 2.6 1.7 2.2 1.3 4.0 0.0 0.0 199.5 0.2 0.3 0.3 10.2 14.6 0.0 0.0 0.7 0.0 0.0 16.8 160.7 1.8 0.0 0.0 0.3 0.4 0.0 0.2 0.0 3.7 0.0 0.2 1.0 2.0 4.0 2.8 23.0 0.0 0.0 0.4 17.3 0.0 0.1 0.8 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.8 0.4 0.0 0.7 0.4 PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "parathyroid gland: 2129.3" "Group enriched" "Detected in some" 7 "Distal tubular cells: 641.8;Horizontal cells: 1527.7" "Cancer enriched" "Detected in many" 4 "renal cancer: 59.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Cell line enriched" "Detected in some" 291 "RPMI-8226: 1561.0" "Region enriched" "Detected in all" 5 "cerebellum: 2120.1" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: AB_563948, HPA048536: AB_2680433" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "unprognostic (9.75e-2)" "unprognostic (1.79e-3)" "unprognostic (7.80e-2)" "unprognostic (2.49e-2)" "unprognostic (2.52e-2)" "unprognostic (6.53e-2)" "unprognostic (2.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (1.91e-1)" "unprognostic (1.65e-2)" "unprognostic (8.99e-3)" 0.4 1.0 82.5 0.7 40.2 0.1 15.0 255.6 86.5 0.1 8.6 0.3 0.2 1.4 0.8 0.1 0.1 0.3 0.2 9.3 100.5 82.1 5.7 2.2 2.4 127.4 85.7 0.5 0.2 2129.3 1.2 2.4 105.7 0.3 0.3 373.5 2.7 0.7 13.6 0.1 0.3 0.5 50.9 3.2 0.8 1.5 275.5 0.3 5.0 0.4 3.1 3.8 0.2 51.8 0.0 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.1 0.4 1561.0 0.0 5.3 2.3 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 4.6 0.0 0.0 0.9 0.3 15.1 82.5 40.2 255.6 86.5 9.3 100.5 127.4 85.7 105.7 50.9 275.5 51.8 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 0.0 51.3 2.4 2.0 0.6 0.0 0.0 38.6 10.4 0.3 0.0 0.0 641.8 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 11.4 0.2 30.0 0.2 53.8 1527.7 29.7 0.0 0.0 2.9 0.0 0.1 0.6 15.7 0.0 2.8 0.1 37.4 0.0 3.0 3.3 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 150.5 0.0 1.0 0.0 0.0 3.6 0.0 0.0 0.4 0.9 0.0 0.0 0.1 RGL3 FLJ32585 ENSG00000205517 "Ral guanine nucleotide dissociation stimulator like 3" Q3MIN7 19 11384341-11419328 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.1;parathyroid gland: 45.9;thyroid gland: 64.9" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Collecting duct cells: 51.5;Gastric mucus-secreting cells: 48.4;Sertoli cells: 39.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CACO-2: 10.4;RT4: 22.0;SK-BR-3: 9.7;T-47d: 15.9" "Region enriched" "Detected in many" 6 "cerebellum: 9.0" "Low region specificity" "Detected in many" "HPA042763, HPA043615, HPA064578" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA042763: AB_10968569, HPA043615: AB_10959470, HPA064578: " "prognostic favorable (7.35e-4)" "unprognostic (3.12e-2)" "unprognostic (2.92e-1)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (6.60e-2)" "unprognostic (3.82e-2)" "unprognostic (5.31e-2)" "unprognostic (1.24e-2)" "unprognostic (1.48e-2)" "unprognostic (3.19e-3)" "unprognostic (5.99e-2)" "prognostic favorable (6.61e-4)" "unprognostic (4.17e-2)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (7.12e-3)" 7.3 11.5 1.8 0.7 1.6 0.0 7.4 1.9 2.5 13.3 6.9 2.9 1.4 4.8 9.5 1.1 9.5 2.1 9.2 2.2 2.2 41.1 10.6 8.9 0.6 2.7 2.4 2.5 21.0 45.9 15.4 5.6 2.8 6.5 1.3 0.8 5.9 9.4 2.0 1.3 1.8 0.8 1.7 8.2 13.8 0.6 2.9 0.2 64.9 0.6 0.3 5.3 5.7 2.3 0.0 0.6 0.0 0.1 1.1 0.2 17.7 1.1 1.4 0.6 2.0 10.4 7.4 0.0 6.5 1.3 2.6 4.6 0.0 0.0 0.1 0.0 0.0 0.1 4.2 3.3 2.7 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.9 1.4 0.0 0.7 2.2 6.3 22.0 1.0 5.2 0.2 9.7 3.3 3.7 15.9 0.0 0.0 3.3 0.0 2.5 0.9 0.0 0.6 1.0 0.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.9 2.5 2.2 2.2 2.7 2.4 2.8 1.7 2.9 2.3 3.1 19.2 21.0 32.3 1.1 0.1 2.1 0.4 1.8 0.3 3.3 4.6 4.6 12.8 12.4 51.5 0.0 12.9 0.0 2.2 11.7 8.6 0.0 14.8 9.6 5.8 10.3 0.0 0.5 4.2 11.9 4.1 48.4 18.4 1.3 3.1 26.0 5.8 3.0 0.0 0.6 7.7 2.0 7.4 0.3 0.2 3.7 1.5 5.4 4.7 0.0 16.9 0.0 1.5 0.5 5.7 5.3 0.4 0.6 1.4 0.0 4.6 1.7 0.6 39.5 9.9 18.7 0.6 1.7 0.0 0.0 12.0 0.2 0.8 2.4 2.0 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28259246-28323849 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.8;skeletal muscle: 44.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Excitatory neurons: 38.2;Granulosa cells: 26.3;NK-cells: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 28.8;AN3-CA: 20.9;NTERA-2: 29.6;REH: 32.6;SCLC-21H: 45.5;SH-SY5Y: 42.6" "Region enriched" "Detected in all" 5 "cerebellum: 275.9" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.15e-2)" "prognostic favorable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.1 2.4 8.0 0.9 7.0 1.3 0.8 26.8 15.0 0.7 0.0 0.3 0.3 0.9 0.4 0.6 0.7 0.2 2.1 11.6 6.7 1.8 0.2 0.8 1.7 6.6 7.6 0.5 1.9 2.9 5.6 0.0 6.7 1.5 0.3 5.0 2.7 0.2 44.1 1.1 0.6 0.1 3.2 1.9 0.8 2.5 12.8 10.0 2.5 9.1 0.8 0.3 0.3 7.9 0.3 0.4 28.8 20.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.2 1.4 0.7 0.2 0.0 0.4 0.5 8.8 0.2 0.1 3.0 1.2 0.1 0.3 0.9 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.2 0.2 11.2 0.0 1.8 0.0 3.6 14.0 0.3 29.6 1.9 0.2 32.6 1.6 0.6 0.1 1.8 45.5 42.6 0.8 2.7 0.4 3.5 3.3 0.1 0.8 0.1 4.3 0.4 0.2 0.3 0.0 0.5 0.1 0.5 1.6 0.3 0.0 0.0 1.5 0.0 0.5 0.0 0.4 0.8 0.0 0.1 0.4 1.0 0.0 0.7 0.0 0.0 0.5 0.1 8.0 7.0 26.8 15.0 11.6 6.7 6.6 7.6 6.7 3.2 12.8 7.9 0.2 3.2 0.5 1.0 0.6 0.6 0.7 1.4 3.4 13.0 6.3 2.9 3.6 2.8 2.5 0.0 81.3 0.0 11.1 0.1 1.9 8.2 1.2 2.4 0.3 0.3 6.0 0.4 38.2 5.6 0.0 0.4 0.0 1.8 0.0 26.3 0.0 0.2 0.1 0.0 13.8 0.8 4.1 0.0 0.8 3.9 0.6 0.4 0.0 0.0 0.7 4.1 36.0 5.0 1.7 3.6 0.0 0.0 2.3 1.5 0.1 0.7 1.7 2.7 0.0 2.5 2.7 2.4 2.1 1.0 0.1 0.1 5.6 0.2 1.2 0.4 SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Club cells: 64.8;Collecting duct cells: 57.0;Distal enterocytes: 262.8;Ionocytes: 107.8;Paneth cells: 73.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 33.3;RPMI-8226: 9.2;RT4: 18.5;U-266/70: 55.4;U-266/84: 20.2" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" 18.5 0.4 0.0 1.1 0.0 0.2 17.7 1.0 0.0 48.5 0.0 94.2 2.5 2.8 0.1 82.8 3.7 0.5 0.3 0.0 0.0 31.7 0.2 23.9 0.8 0.0 0.0 0.7 2.1 0.3 1.0 3.6 0.1 10.5 35.6 0.0 39.5 2.4 1.4 36.0 4.3 0.8 0.0 3.7 24.1 0.3 0.0 0.7 9.2 0.8 5.4 8.3 56.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 9.2 0.0 18.5 0.2 0.0 0.0 0.5 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 55.4 20.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.7 99.3 28.3 0.0 7.1 3.1 15.4 27.8 5.7 0.0 4.4 3.0 0.7 0.0 64.8 57.0 0.0 0.7 0.1 262.8 0.0 0.0 0.1 11.9 1.6 6.2 7.7 0.0 0.3 0.4 0.3 1.0 36.7 23.4 8.2 0.0 1.1 0.1 0.1 0.0 0.3 21.4 107.8 0.0 0.0 0.2 0.0 1.0 10.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 73.7 0.0 38.7 6.1 0.0 0.1 9.2 0.0 0.0 0.1 0.7 0.1 0.4 29.8 5.4 2.2 1.4 0.0 15.2 19.7 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SHF ENSG00000138606 "Src homology 2 domain containing F" Q7M4L6 15 45167214-45201175 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.6;Granulosa cells: 58.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 143.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 121.0;SH-SY5Y: 54.1" "Region enriched" "Detected in all" 5 "cerebellum: 240.6" "Region enriched" "Detected in all" 4 "cerebellum: 106.2" HPA057381 Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA057381: AB_2683423" "unprognostic (4.05e-2)" "unprognostic (2.02e-3)" "unprognostic (7.59e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" "unprognostic (7.61e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (6.88e-2)" "unprognostic (5.12e-2)" "unprognostic (6.89e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (5.09e-3)" "unprognostic (1.83e-2)" 6.1 22.7 21.9 4.3 20.5 1.0 6.3 143.8 27.8 14.4 0.2 13.4 13.1 11.9 4.7 5.0 10.5 6.6 9.0 21.5 19.5 4.4 38.6 5.6 2.7 12.8 16.9 23.7 3.1 4.4 8.3 1.9 15.9 10.1 5.3 7.1 6.7 5.9 3.8 12.7 8.4 7.5 9.4 4.3 6.7 8.4 21.4 2.4 7.5 4.7 1.9 10.2 11.7 13.4 0.1 1.4 24.0 0.7 1.8 0.9 11.2 3.0 2.1 6.7 9.5 3.6 11.6 1.3 9.5 4.2 6.6 2.1 9.2 0.7 3.2 2.2 4.2 0.8 2.2 24.8 1.0 0.1 8.0 2.2 0.6 0.9 0.2 5.0 5.2 12.0 5.0 0.5 9.5 4.1 5.5 0.9 9.6 4.5 0.6 15.0 19.1 0.5 2.3 0.5 121.0 54.1 0.7 0.8 0.4 7.4 1.2 2.4 0.3 0.8 10.0 0.7 0.4 1.1 0.9 1.1 0.3 0.6 3.8 0.1 0.6 0.5 1.3 0.6 1.4 0.8 0.5 0.8 0.6 1.5 0.7 0.5 0.8 2.0 0.6 0.9 0.1 0.5 21.9 20.5 143.8 27.8 21.5 19.5 12.8 16.9 15.9 9.4 21.4 13.4 4.1 0.0 0.6 3.3 4.2 3.6 5.8 1.7 0.0 50.6 3.6 5.5 2.8 0.0 1.3 0.0 0.0 1.1 2.6 2.1 0.0 0.8 7.9 1.1 3.5 5.7 13.1 0.0 5.9 1.3 0.5 5.8 1.5 2.2 2.5 58.8 5.3 11.7 0.6 10.1 6.9 10.9 2.0 1.0 15.0 15.3 4.4 2.9 8.8 5.6 0.1 5.9 2.1 9.0 1.8 0.7 5.6 4.1 0.7 3.5 18.0 1.1 0.8 5.0 6.6 6.7 9.6 5.4 2.9 1.4 2.6 0.7 2.8 1.8 4.6 9.7 SKOR2 "CORL2, Fussel-18, FUSSEL18" ENSG00000215474 "SKI family transcriptional corepressor 2" Q2VWA4 18 47206169-47251660 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 1.8;Spermatocytes: 2.5;Spermatogonia: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "NTERA-2: 3.9" "Region enriched" "Detected in single" 5 "cerebellum: 2.4" "Not detected" "Not detected" HPA046206 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA046206: AB_2679588" "unprognostic (1.53e-1)" "unprognostic (1.93e-1)" "unprognostic (1.92e-1)" "unprognostic (6.31e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.8 0.6 1.8 0.2 1.1 2.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.2" "Cell type enhanced" "Detected in many" "Adipocytes: 61.8;Extravillous trophoblasts: 239.4;Melanocytes: 60.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 197.2;RPTEC TERT1: 193.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in some" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" 32.4 5.6 26.2 1.8 24.0 1.3 23.4 24.2 35.7 11.1 19.6 9.8 1.2 8.7 0.3 16.7 13.1 1.8 48.6 23.9 25.4 35.8 5.0 57.2 2.4 26.5 24.8 6.5 4.9 3.8 2.9 4.7 28.0 5.9 1.8 21.5 8.5 1.0 18.8 25.6 9.2 0.8 25.7 6.6 13.5 2.1 31.6 1.1 8.6 5.6 3.2 12.0 16.8 24.9 14.8 19.1 0.8 10.8 2.5 2.1 26.5 4.7 16.6 14.1 5.4 32.0 14.9 17.8 44.2 0.5 9.6 22.0 16.4 1.0 5.4 2.1 9.6 21.7 22.1 23.8 0.1 16.6 6.7 0.0 6.5 0.3 6.2 4.2 2.5 10.7 17.1 4.6 0.0 14.8 17.2 63.9 5.4 74.1 197.2 30.6 1.1 26.2 193.9 14.2 17.4 25.1 4.1 4.4 15.7 6.5 1.0 7.5 2.8 0.4 10.5 7.0 27.2 9.2 15.9 11.1 38.1 24.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.9 0.7 0.2 0.1 0.0 0.0 0.0 0.0 1.6 0.2 26.2 24.0 24.2 35.7 23.9 25.4 26.5 24.8 28.0 25.7 31.6 24.9 61.8 3.2 1.3 1.3 13.1 27.3 1.4 19.8 1.2 14.1 1.2 0.8 4.4 1.5 5.9 25.8 31.3 2.1 3.7 7.5 0.0 5.9 0.3 8.7 3.6 40.3 0.0 2.1 7.9 2.5 239.4 4.3 20.9 35.6 0.0 0.0 14.6 0.6 5.5 0.0 6.6 8.4 2.0 9.7 33.5 0.7 0.3 11.9 60.5 3.7 0.0 6.1 0.0 1.5 0.3 11.8 1.9 0.7 19.1 3.5 0.8 9.6 1.3 43.2 0.0 1.9 2.9 0.2 3.0 1.1 16.1 23.5 5.6 0.1 7.5 11.0 STAP1 "BRDG1, STAP-1" ENSG00000035720 "Signal transducing adaptor family member 1" Q9ULZ2 4 67558727-67607337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 51.0" "Group enriched" "Detected in some" 5 "B-cells: 60.8;granulocytes: 80.8;Ionocytes: 65.1;Plasma cells: 147.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 13.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 88.1;naive B-cell: 107.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 185.4;U-698: 83.2" "Region enriched" "Detected in single" 5 "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA038529 Enhanced Uncertain Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "HPA038529: AB_10673011" "unprognostic (1.14e-4)" "unprognostic (1.49e-3)" "unprognostic (2.30e-2)" "unprognostic (2.17e-1)" "unprognostic (1.63e-3)" "unprognostic (6.30e-4)" "unprognostic (1.95e-3)" "unprognostic (6.95e-3)" "unprognostic (5.18e-2)" "unprognostic (6.38e-3)" "unprognostic (1.47e-1)" "unprognostic (8.43e-3)" "unprognostic (3.11e-2)" "unprognostic (1.49e-2)" "unprognostic (4.69e-2)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" 0.4 0.1 0.0 15.5 0.0 5.8 0.8 0.0 0.0 0.3 0.0 2.3 1.8 0.6 1.9 0.7 0.1 1.4 0.2 0.5 0.0 9.2 0.4 1.4 40.8 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.9 2.3 0.0 1.3 2.8 0.1 0.1 8.1 0.4 0.0 16.0 2.3 2.7 0.0 6.4 0.4 0.0 51.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 24.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 83.2 0.0 24.7 0.0 5.3 0.1 24.3 0.9 0.1 1.9 88.1 2.0 0.8 1.2 107.8 7.9 0.2 1.0 38.9 0.1 5.2 0.4 4.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.7 0.0 60.8 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.7 5.5 0.0 0.0 5.8 0.0 9.8 0.0 13.0 0.1 0.0 0.6 0.0 2.5 0.3 0.0 0.0 0.1 0.0 0.0 80.8 0.0 0.4 0.0 0.8 0.0 0.2 0.1 65.1 0.3 0.7 7.1 0.3 1.2 16.0 0.0 0.2 0.0 6.2 0.0 0.3 0.0 0.0 0.4 147.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 3.7 0.2 0.1 0.1 0.0 4.3 0.1 0.0 0.2 STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.5;Paneth cells: 343.4;Proximal enterocytes: 415.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 7.9;T-cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 87.3;HaCaT: 70.3;MCF7: 104.3;RT4: 138.1" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" 5.6 18.1 2.6 7.5 2.7 0.4 16.6 3.6 4.2 18.1 3.5 72.8 77.5 5.7 10.6 91.0 15.1 7.1 4.9 2.7 2.4 28.5 55.3 8.2 3.2 2.4 2.2 11.5 30.6 21.3 4.4 3.4 2.7 37.9 59.7 0.5 45.4 9.8 1.2 73.9 72.0 4.0 2.0 1.5 24.2 2.0 2.5 7.9 15.3 0.7 13.0 16.5 41.0 2.6 87.3 0.4 6.2 5.8 0.4 4.7 35.7 1.6 8.8 2.8 2.2 52.0 34.8 0.1 13.3 2.8 17.9 70.3 1.1 50.3 1.6 14.9 0.7 0.3 0.4 35.1 10.9 0.1 0.7 3.5 41.7 4.8 12.2 7.0 8.9 2.1 3.4 18.6 1.3 104.3 1.3 0.7 4.8 55.3 20.4 3.6 0.8 2.2 29.4 138.1 2.1 3.5 0.1 25.9 14.6 2.2 60.7 0.3 12.5 0.2 1.2 0.7 1.8 0.1 1.4 1.3 0.3 0.4 5.7 0.4 0.1 0.0 0.6 0.0 2.3 0.6 0.8 0.1 0.7 0.1 2.3 1.4 0.1 7.9 0.0 2.2 2.5 0.8 2.6 2.7 3.6 4.2 2.7 2.4 2.4 2.2 2.7 2.0 2.5 2.6 6.7 9.6 14.4 0.3 2.4 40.5 59.8 171.4 42.7 0.6 33.8 30.1 6.9 38.6 87.2 29.5 0.0 16.9 2.3 294.5 25.4 137.5 1.2 9.0 3.6 10.1 85.8 4.4 1.5 101.0 3.0 4.5 55.5 13.4 8.9 5.2 7.5 29.6 1.8 0.0 1.2 147.5 91.6 4.1 9.4 0.9 4.7 1.8 19.6 0.0 12.5 1.0 1.0 0.5 1.8 139.4 343.4 1.9 1.4 92.6 415.7 125.0 44.9 0.8 0.0 1.7 7.9 0.6 2.6 86.0 61.8 12.4 3.3 5.7 173.2 117.0 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 376.2;lymphoid tissue: 113.3" "Cell type enhanced" "Detected in many" "B-cells: 229.3;dendritic cells: 267.7;granulocytes: 195.1;Langerhans cells: 201.3;Macrophages: 198.9;Plasma cells: 191.8;T-cells: 342.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 122.3;HMC-1: 118.9;Karpas-707: 111.6;U-698: 132.1" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 28.2 8.9 2.1 67.0 2.9 376.2 21.5 3.7 5.3 24.2 3.3 19.1 27.8 5.4 1.8 11.9 5.8 20.4 4.6 4.1 3.3 6.5 8.5 23.6 113.3 3.1 2.0 2.2 12.7 2.1 3.0 16.7 3.2 10.5 17.5 0.4 17.0 5.7 2.4 11.2 40.1 16.8 2.2 56.9 20.1 9.5 4.0 60.9 7.2 3.5 111.1 24.4 5.2 2.9 11.0 7.5 11.2 4.2 47.7 18.1 12.4 25.7 38.4 27.7 28.5 22.8 3.9 122.3 23.1 14.8 7.3 7.4 4.7 11.1 33.4 21.8 12.7 11.6 9.1 2.2 14.2 47.0 118.9 23.1 10.9 34.3 17.7 39.2 11.5 28.5 9.1 111.6 69.4 5.9 61.6 106.0 6.3 19.9 17.2 10.1 67.5 37.4 16.3 25.6 4.2 4.2 6.6 6.4 5.4 17.2 4.3 24.3 14.0 26.8 13.1 19.3 14.7 45.5 78.9 132.1 20.2 15.9 12.1 165.1 74.3 163.1 43.7 81.3 55.4 49.2 77.0 52.8 53.0 58.6 98.6 82.4 236.7 40.8 113.1 37.7 73.8 89.3 2.1 2.9 3.7 5.3 4.1 3.3 3.1 2.0 3.2 2.2 4.0 2.9 23.3 89.8 74.0 48.3 229.3 59.9 27.1 15.1 10.8 0.9 28.9 15.2 2.6 12.8 42.5 11.0 0.0 7.9 267.7 54.0 3.9 6.6 6.8 15.3 14.1 11.3 3.0 68.8 3.4 2.8 24.0 27.2 38.2 26.5 195.1 47.4 5.3 2.4 26.1 0.0 3.1 13.9 18.3 151.1 201.3 3.6 5.6 198.9 58.7 11.2 158.0 0.6 118.4 17.6 0.7 10.9 41.6 4.5 191.8 34.3 80.7 2.5 26.9 0.3 6.6 49.7 19.7 41.1 26.3 16.4 63.4 5.1 342.5 22.6 13.2 53.8 SYCP1 "CT8, HOM-TES-14, SCP1" ENSG00000198765 "Synaptonemal complex protein 1" Q15431 1 114854863-114995370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "testis: 40.2" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 1162.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 98 "THP-1: 17.2" "Region enriched" "Detected in single" 51 "cerebellum: 14.7" "Not detected" "Not detected" HPA021083 Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies, Cytosol" "HPA021083: AB_1857685" "unprognostic (2.91e-1)" "unprognostic (6.89e-3)" "unprognostic (4.87e-1)" "unprognostic (8.74e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.5 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 56.7 5.3 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1162.6 32.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SYNE4 "C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4" ENSG00000181392 "Spectrin repeat containing nuclear envelope family member 4" Q8N205 19 36003307-36008813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 32.0;Breast myoepithelial cells: 35.9;Cytotrophoblasts: 32.6;Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 32.5;Hep G2: 29.1;MCF7: 34.2;SK-BR-3: 40.1;T-47d: 31.0" "Region enriched" "Detected in single" 15 "cerebellum: 6.8" "Not detected" "Not detected" HPA060253 Uncertain NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA060253: AB_2684233" "unprognostic (8.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.24e-1)" "unprognostic (5.54e-2)" "unprognostic (2.42e-3)" "unprognostic (3.76e-2)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (3.36e-3)" "unprognostic (6.02e-2)" "prognostic favorable (8.64e-9)" "unprognostic (1.25e-1)" "unprognostic (2.54e-2)" "unprognostic (4.50e-1)" "unprognostic (1.97e-2)" 0.2 0.2 1.2 0.2 1.0 0.2 5.2 6.7 1.5 2.6 2.5 1.9 3.2 0.7 7.7 1.2 3.9 1.6 0.2 0.7 2.9 8.4 12.0 3.1 0.2 3.7 3.0 0.3 5.4 12.1 12.7 1.6 3.6 10.9 1.4 0.2 9.2 4.0 0.3 1.1 1.3 0.2 1.3 0.3 3.4 0.2 2.5 1.7 8.6 0.0 0.3 0.8 1.3 1.2 0.3 0.3 0.2 0.4 0.1 0.2 4.3 0.0 0.0 0.0 0.1 32.5 3.8 0.3 0.4 0.0 0.2 0.0 0.3 0.4 0.0 1.1 0.5 0.1 0.8 29.1 0.5 0.0 0.2 0.2 0.2 1.1 0.0 0.0 0.2 1.6 0.4 0.4 0.0 34.2 0.5 0.1 0.2 0.3 0.2 0.9 0.0 0.4 2.2 1.0 5.0 0.0 0.0 40.1 0.2 0.2 31.0 0.3 0.0 0.3 0.6 0.5 0.2 0.5 0.7 0.6 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 6.7 1.5 0.7 2.9 3.7 3.0 3.6 1.3 2.5 1.2 0.3 6.4 17.5 0.3 0.7 0.5 14.9 19.9 5.2 0.9 32.0 35.9 0.4 24.3 20.2 29.5 4.2 32.6 0.8 5.4 25.4 21.2 0.0 9.1 1.0 0.8 29.8 0.0 0.6 8.6 24.7 0.7 8.2 10.7 1.3 0.5 0.7 12.5 2.6 0.0 0.9 10.6 26.4 0.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.9 11.7 16.9 0.0 0.0 23.9 4.5 24.2 17.3 0.4 0.0 0.3 1.6 0.1 0.4 2.1 0.4 33.9 1.2 0.1 8.8 9.2 TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 127.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 50.3;Exocrine glandular cells: 38.3;Hepatic stellate cells: 32.2;Proximal enterocytes: 37.9;Syncytiotrophoblasts: 34.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 364.1" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" 17.4 5.2 4.2 7.1 3.6 0.4 12.0 5.6 5.5 10.4 4.0 8.1 4.8 9.7 1.0 7.8 8.3 4.5 20.0 3.5 3.9 33.7 4.6 26.0 1.6 5.3 4.8 4.5 51.1 1.6 3.4 10.9 6.1 8.5 4.1 0.5 8.0 5.0 127.3 16.4 8.4 8.9 4.0 9.0 8.1 3.7 6.4 1.6 23.6 46.7 2.4 11.3 7.1 3.6 37.6 51.5 13.0 36.2 4.0 8.7 137.8 29.5 15.6 49.7 27.8 99.6 39.0 0.3 22.2 22.5 34.0 52.5 51.2 364.1 46.1 0.2 41.2 59.1 43.7 87.7 18.8 12.8 10.7 12.2 14.8 43.3 66.7 20.8 42.9 23.4 38.4 0.5 17.5 53.2 0.7 0.3 99.5 48.0 30.0 27.4 73.7 28.9 23.6 15.3 7.4 13.2 36.4 89.9 27.1 93.8 61.2 21.8 49.4 28.7 100.1 20.2 15.7 0.1 0.2 0.4 23.3 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.6 5.6 5.5 3.5 3.9 5.3 4.8 6.1 4.0 6.4 3.6 17.1 12.8 4.7 0.0 0.1 12.2 12.6 6.1 9.1 0.1 6.6 3.7 2.4 5.7 2.3 7.3 0.0 50.3 0.4 3.7 5.9 17.7 0.3 3.0 5.1 25.9 0.0 0.0 1.6 38.3 18.3 6.6 4.1 5.0 5.7 3.4 32.2 0.4 5.2 0.0 0.5 3.7 2.0 0.8 1.5 2.3 0.0 0.5 8.8 3.7 0.0 0.0 0.0 0.0 0.4 21.1 0.9 0.4 1.2 28.9 37.9 21.1 1.5 0.1 0.0 9.3 12.2 0.5 6.4 5.4 7.7 34.6 0.5 0.4 7.1 4.9 TEX36 "bA383C5.1, C10orf122" ENSG00000175018 "Testis expressed 36" Q5VZQ5 10 125576522-125683163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 26.8" "Group enriched" "Detected in some" 53 "Early spermatids: 358.7;Late spermatids: 347.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "U-2197: 8.3" "Region enriched" "Detected in single" 15 "cerebellum: 2.3" "Low region specificity" "Detected in some" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (7.72e-3)" "unprognostic (3.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.7 0.5 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 347.6 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 3.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 TGM5 "TGMX, TGX" ENSG00000104055 "Transglutaminase 5" O43548 15 43232590-43266928 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 12.0;skin 1: 39.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.6;Club cells: 4.3;Early spermatids: 3.2;Late spermatids: 4.0;Suprabasal keratinocytes: 6.7;Urothelial cells: 12.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 16.6" "Region enriched" "Detected in single" 12 "cerebellum: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (3.17e-2)" "unprognostic (1.03e-2)" "unprognostic (5.92e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.44e-15)" "unprognostic (1.94e-1)" "unprognostic (3.14e-1)" "unprognostic (7.22e-3)" "unprognostic (5.71e-2)" 0.8 0.0 0.0 0.0 0.0 0.2 1.7 0.2 0.0 3.9 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 4.3 1.2 0.3 39.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.5 7.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.3 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.2 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 2.6 1.5 0.0 0.0 1.0 0.5 0.2 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.8 6.7 1.9 0.0 0.0 0.0 12.1 TLDC2 "C20orf118, dJ132F21.2" ENSG00000101342 "TBC/LysM-associated domain containing 2" A0PJX2 20 36876121-36894235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 10.2;granulocytes: 15.2;Intestinal goblet cells: 4.9;Paneth cells: 11.5;Proximal enterocytes: 20.4;Undifferentiated cells: 7.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "basophil: 4.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.6" "Cell line enriched" "Detected in some" 6 "HMC-1: 34.7" "Region enriched" "Detected in many" 4 "cerebellum: 5.7" "Low region specificity" "Detected in all" HPA047468 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA047468: AB_2680059" "unprognostic (9.06e-3)" "unprognostic (3.35e-4)" "unprognostic (4.60e-1)" "unprognostic (1.07e-3)" "unprognostic (1.40e-1)" "unprognostic (6.51e-3)" "unprognostic (1.09e-3)" "unprognostic (5.55e-2)" "unprognostic (1.62e-1)" "unprognostic (2.82e-2)" "unprognostic (3.67e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.97e-5)" "unprognostic (7.25e-2)" "unprognostic (6.20e-2)" "unprognostic (5.59e-2)" "unprognostic (4.87e-2)" 10.0 2.6 0.6 4.7 0.9 1.6 6.5 0.1 0.8 6.3 2.7 11.7 18.2 2.7 0.4 3.2 8.0 2.7 7.0 0.4 1.0 5.9 2.3 11.1 2.8 1.5 1.0 5.1 4.3 0.0 2.8 0.2 1.4 3.8 12.3 1.3 4.1 0.2 2.0 4.7 17.1 0.7 0.9 7.9 3.6 3.0 1.7 0.0 4.1 0.0 0.1 5.5 5.6 2.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 1.6 0.5 0.4 0.2 0.7 0.3 0.4 0.0 0.0 0.0 0.1 0.3 1.3 0.6 4.0 0.0 0.4 34.7 0.1 0.2 0.1 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 1.2 0.0 6.2 1.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.6 0.3 0.2 0.1 0.0 0.0 0.2 0.1 4.6 0.5 0.0 0.2 0.6 0.2 0.1 0.2 0.1 0.8 0.6 0.5 0.1 0.0 0.8 0.7 0.4 0.4 0.5 0.6 0.9 0.1 0.8 0.4 1.0 1.5 1.0 1.4 0.9 1.7 2.1 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.4 10.2 0.0 0.5 0.3 0.3 0.1 0.1 3.6 0.8 0.3 0.0 0.0 0.5 1.1 0.3 15.2 0.3 0.0 0.0 0.3 0.0 0.3 4.9 0.0 0.0 0.5 0.4 0.0 0.3 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.5 11.5 0.0 0.1 0.0 20.4 0.2 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.4 0.1 7.3 0.0 TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "brain: 9.0" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 7.7" "Cancer enhanced" "Detected in some" "cervical cancer: 1.7" "Group enriched" "Detected in many" 6 "cerebellum: 9.0;medulla oblongata: 2.3;spinal cord: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 25.9" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 8 "cerebellum: 15.5" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA030504: AB_2732458, HPA060957: AB_2732655, HPA069359: AB_2732130" "unprognostic (3.52e-2)" "unprognostic (2.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (2.76e-2)" "unprognostic (4.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 2.3 0.6 1.0 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.4;skeletal muscle: 5.8;tongue: 2.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Cytotrophoblasts: 16.0;Early spermatids: 7.0;Late spermatids: 19.7;Rod photoreceptor cells: 9.1;Sertoli cells: 6.6;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.3" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in many" 5 "cerebellum: 26.8" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" 0.0 0.9 0.9 0.0 1.0 0.0 0.1 8.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.5 0.0 0.5 0.1 0.6 0.8 0.0 1.1 0.0 1.2 0.9 0.7 0.1 0.0 1.1 0.0 0.0 5.8 0.5 0.0 0.0 0.5 0.1 0.0 0.6 1.4 0.3 0.0 2.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 8.4 1.7 1.2 0.9 0.6 0.8 0.7 0.5 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 4.3 0.5 0.5 0.0 0.0 0.0 1.8 10.4 16.0 0.0 0.0 1.9 0.0 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.2 2.2 0.9 1.5 0.1 0.0 0.2 0.4 0.4 4.5 1.7 0.0 0.0 0.0 0.3 0.0 19.7 0.0 0.4 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.0 0.0 0.7 1.5 9.1 6.6 1.3 0.2 0.5 6.3 0.0 0.0 5.9 0.2 0.5 0.0 0.7 TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.2;Fibroblasts: 168.7;Hofbauer cells: 240.6;Leydig cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" 129.1 37.1 15.8 29.6 14.7 11.8 102.0 17.9 18.7 90.9 44.1 60.3 13.7 84.2 9.2 26.1 85.8 54.1 57.6 15.6 17.4 60.8 37.6 101.4 46.3 17.1 16.7 91.3 32.5 17.6 24.2 61.6 15.6 52.9 10.5 2.5 34.2 33.7 25.7 56.3 43.3 27.5 15.5 85.0 37.0 16.8 18.2 13.2 79.9 22.9 12.7 66.8 71.8 12.9 30.7 238.7 40.8 73.6 61.2 121.4 27.5 153.0 182.5 118.4 81.3 49.5 37.5 2.3 60.4 221.3 68.2 11.3 14.5 145.6 22.2 20.4 17.4 32.5 75.7 71.6 201.4 10.4 38.9 211.5 26.1 42.8 129.0 116.1 78.5 12.5 13.5 184.5 115.8 64.6 7.0 13.0 52.3 39.2 172.7 24.2 29.1 55.4 138.3 2.0 48.0 28.6 75.8 83.6 162.1 17.4 118.5 7.7 116.0 134.2 53.4 27.3 52.2 10.2 1.5 4.5 138.5 11.1 121.8 0.1 146.4 0.1 7.4 143.5 4.6 6.9 3.7 7.2 101.2 5.4 6.2 11.7 3.4 95.6 39.9 7.0 3.6 65.2 15.8 14.7 17.9 18.7 15.6 17.4 17.1 16.7 15.6 15.5 18.2 12.9 194.2 105.8 68.5 6.5 5.6 47.5 22.2 78.8 13.6 9.5 19.4 38.6 9.5 74.4 24.6 31.3 4.2 39.5 8.1 1.7 7.9 82.6 2.1 5.9 43.2 117.3 0.0 12.0 0.6 16.7 31.9 168.7 5.6 10.8 37.2 62.8 97.5 28.2 240.6 13.5 2.9 2.6 4.1 109.9 71.5 7.3 172.7 70.3 147.7 11.2 19.2 43.8 8.2 2.5 0.3 61.3 0.3 95.2 9.3 15.7 0.3 34.7 5.8 6.7 59.2 23.9 67.5 4.7 31.5 6.1 32.8 16.8 10.2 44.7 1.1 6.1 UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844552 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.3;Hofbauer cells: 58.5;NK-cells: 61.8;Pancreatic endocrine cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 245.7;HeLa: 136.3;HMC-1: 245.9;SK-BR-3: 189.7" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1500000 "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Vesicles "HPA067117: AB_2685784, HPA073525: AB_2686615" "unprognostic (6.79e-3)" "unprognostic (4.36e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.93e-1)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (5.28e-12)" "unprognostic (3.27e-2)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (8.59e-2)" 7.7 7.3 5.6 23.5 6.8 58.9 7.8 5.8 7.3 18.6 5.0 10.7 8.0 8.6 2.0 23.6 13.8 6.5 14.3 5.0 5.6 6.6 12.6 38.1 25.9 7.9 6.5 19.3 8.8 0.5 11.6 9.0 7.5 8.1 4.5 5.5 7.7 5.1 8.5 6.0 18.5 4.9 6.2 66.2 13.8 6.1 8.2 20.7 5.9 1.5 17.6 10.7 19.6 8.7 44.0 18.7 0.4 0.3 0.5 1.0 47.6 0.1 0.0 0.0 0.1 41.4 97.0 3.4 46.4 0.0 7.5 15.4 0.0 2.2 0.0 0.4 0.5 245.7 136.3 24.2 3.9 94.1 245.9 0.6 2.0 0.5 2.1 2.3 17.9 42.5 87.1 1.1 0.0 71.2 100.9 50.8 0.9 69.9 1.7 32.8 1.0 1.5 1.6 17.7 0.3 66.7 19.2 189.7 0.9 0.5 47.1 56.5 48.1 0.8 65.9 0.5 0.5 1.3 5.9 4.0 0.6 31.3 0.2 59.1 16.0 31.2 19.3 16.9 17.4 6.7 11.4 13.6 12.3 3.6 8.8 11.9 40.1 14.7 25.6 7.2 10.8 18.1 5.6 6.8 5.8 7.3 5.0 5.6 7.9 6.5 7.5 6.2 8.2 8.7 3.8 44.8 8.3 6.8 16.6 1.1 1.7 1.0 0.6 12.0 4.9 2.4 68.3 7.2 4.4 3.7 20.9 4.7 27.0 40.9 0.0 7.2 5.3 1.3 3.3 6.6 6.0 14.9 1.2 6.0 11.6 2.2 2.0 2.3 45.0 9.9 7.9 1.2 58.5 5.0 1.5 3.6 2.0 21.6 8.2 0.5 2.8 22.2 1.8 5.6 22.5 4.5 61.8 3.0 7.9 47.3 30.7 1.5 27.4 1.6 5.5 0.7 1.6 16.2 0.0 4.5 2.6 1.2 1.4 1.5 1.4 25.9 30.9 2.0 6.3 2.3 UNCX Uncx4.1 ENSG00000164853 "UNC homeobox" A6NJT0 7 1232872-1237326 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 17.5" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "NB-4: 98.5" "Region enriched" "Detected in single" 5 "cerebellum: 3.2" "Region enriched" "Detected in single" 8 "cerebellum: 7.5" HPA063294 Approved Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA063294: AB_2684977" "unprognostic (1.15e-1)" "unprognostic (9.71e-2)" 0.0 0.0 0.7 0.0 0.1 0.0 0.0 17.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.4 0.0 0.0 0.0 2.2 3.0 0.0 0.0 0.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 17.5 0.5 0.0 2.8 2.2 3.0 3.2 0.6 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF385C ENSG00000187595 "Zinc finger protein 385C" Q66K41 17 42025576-42098479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;testis: 8.6" "Cell type enriched" "Detected in many" 4 "Early spermatids: 27.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.5" "Cell line enhanced" "Detected in some" "HDLM-2: 4.3;Hep G2: 16.6;MOLT-4: 4.9;SCLC-21H: 8.6" "Region enriched" "Detected in many" 12 "cerebellum: 28.2" "Region enhanced" "Detected in all" "cerebellum: 19.7" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.58e-3)" "unprognostic (3.38e-2)" "unprognostic (2.02e-3)" "unprognostic (3.95e-2)" "unprognostic (3.95e-2)" "unprognostic (2.61e-1)" "unprognostic (3.07e-1)" "unprognostic (2.64e-1)" "unprognostic (2.48e-1)" "unprognostic (8.67e-3)" "unprognostic (1.10e-1)" "unprognostic (8.90e-2)" "unprognostic (2.59e-1)" "unprognostic (8.71e-2)" "unprognostic (1.50e-1)" "unprognostic (6.22e-2)" "unprognostic (6.05e-2)" 0.5 0.1 2.5 0.3 2.6 0.9 1.6 12.8 3.1 0.8 1.6 0.5 0.1 0.9 1.3 0.6 1.9 0.3 0.3 2.5 3.2 0.9 0.3 0.5 0.5 2.7 3.1 2.5 2.1 0.9 2.5 0.4 3.3 1.2 0.3 4.9 1.5 0.6 2.1 0.7 0.4 0.2 2.1 0.3 0.4 8.6 2.9 1.8 0.5 5.3 0.3 0.4 0.7 2.9 0.3 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.4 1.8 0.0 0.6 0.0 0.0 0.5 0.3 0.1 0.0 4.3 3.2 0.2 0.1 16.6 0.3 0.0 0.4 0.0 2.5 0.0 0.6 0.1 0.0 2.5 0.2 0.0 0.0 0.4 4.9 0.2 0.6 0.8 0.0 0.3 0.0 1.0 0.1 0.2 8.6 0.3 0.1 0.4 0.4 0.9 1.6 1.2 0.0 0.0 0.2 0.1 0.0 1.2 0.4 0.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 2.5 2.6 12.8 3.1 2.5 3.2 2.7 3.1 3.3 2.1 2.9 2.9 0.6 0.0 0.5 1.6 0.5 0.4 1.9 2.2 0.0 5.0 1.2 2.2 0.5 1.5 1.5 1.8 0.0 0.2 2.7 0.4 1.9 0.5 27.3 0.3 0.3 0.3 0.0 0.0 2.1 0.5 0.1 0.5 0.5 0.7 0.0 0.8 0.0 0.0 0.8 1.7 3.0 0.5 2.0 0.6 0.9 5.1 1.5 0.3 0.0 5.6 0.0 3.0 1.0 3.5 4.2 0.2 0.3 0.0 0.0 4.1 0.6 0.1 0.5 2.2 0.0 1.4 0.5 1.0 1.9 0.0 0.6 0.0 0.2 0.0 0.6 1.3