Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "choroid plexus: 144.6;retina: 461.0" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 450.4;Rod photoreceptor cells: 482.9" "Cancer enhanced" "Detected in many" "lung cancer: 3.1" "Region enriched" "Detected in some" 6 "hippocampal formation: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;EFO-21: 6.8;HeLa: 2.3;SK-BR-3: 3.0;SuSa: 3.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Approved Cytosol NA NA "Cluster 79: Retina - Phototransduction" "Cluster 38: EFO-21 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA064420: , HPA078826: " "unprognostic (1.25e-1)" "unprognostic (3.93e-1)" "unprognostic (3.29e-2)" "unprognostic (7.17e-4)" "unprognostic (1.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.45e-4)" "unprognostic (3.77e-2)" "unprognostic (5.25e-1)" "unprognostic (3.70e-1)" "unprognostic (5.18e-2)" "unprognostic (1.17e-9)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.72e-4)" 0.5 0.0 0.4 0.1 0.3 0.0 0.8 1.1 0.7 0.5 144.6 0.2 2.5 0.1 8.4 0.2 0.4 0.1 0.2 9.3 0.1 8.7 0.9 0.3 0.4 0.4 0.5 0.2 0.0 0.0 0.1 0.6 0.2 0.2 0.1 461.0 0.0 1.4 0.1 2.1 2.9 0.0 0.1 0.1 0.1 1.0 1.4 0.3 0.4 0.0 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 6.8 0.3 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 2.3 0.7 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.9 0.5 0.0 1.2 0.0 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.6 3.0 0.1 3.1 0.3 0.0 0.1 0.2 1.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.1 0.7 9.3 0.1 0.4 0.5 0.2 0.1 1.4 0.4 1.2 0.0 1.1 1.3 0.0 0.1 0.2 1.7 0.0 27.9 0.5 1.3 1.1 0.0 1.8 7.3 450.4 0.3 0.0 0.0 0.0 0.0 8.8 0.3 0.1 3.1 0.0 0.0 0.4 0.0 1.5 0.2 0.0 0.9 0.0 0.2 1.4 0.3 0.1 10.1 0.6 16.2 0.0 0.3 0.0 21.9 0.0 0.0 0.0 19.7 0.0 37.3 0.0 0.5 0.0 0.0 0.0 0.4 0.0 2.6 1.3 0.4 2.3 482.9 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.6 0.7 ABCG4 WHITE2 ENSG00000172350 "ATP binding cassette subfamily G member 4" Q9H172 11 119149052-119162653 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 52.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.8;Cone photoreceptor cells: 58.4;Inhibitory neurons: 9.8;Rod photoreceptor cells: 46.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9;HAP1: 1.0;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057635 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA057635: " "unprognostic (3.26e-2)" "unprognostic (4.75e-4)" "unprognostic (6.31e-2)" "unprognostic (1.83e-3)" "unprognostic (3.76e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "unprognostic (9.35e-2)" "unprognostic (1.67e-1)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (8.78e-2)" "unprognostic (2.25e-1)" "unprognostic (4.15e-4)" "unprognostic (2.26e-1)" "unprognostic (6.48e-3)" "unprognostic (2.65e-3)" 0.3 0.4 4.0 0.1 4.4 0.0 0.1 7.5 11.3 0.4 0.0 0.3 0.2 0.5 0.3 0.9 0.2 0.3 0.8 4.2 5.8 0.4 0.1 0.1 0.0 6.9 3.9 0.1 0.3 1.8 0.3 0.1 6.8 0.3 0.1 52.0 0.2 0.6 0.1 0.3 0.2 0.4 1.5 0.1 0.2 5.8 6.2 2.9 0.8 0.2 0.5 0.1 0.6 5.6 0.1 0.4 0.4 1.9 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.0 0.8 0.1 1.0 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.3 0.0 0.2 0.4 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.1 0.1 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 4.4 7.5 11.3 4.2 5.8 6.9 3.9 6.8 1.5 6.2 5.6 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.9 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.1 6.7 9.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 2.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 0.0 0.0 0.3 2.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 AC010319.2 ENSG00000269035 "Novel protein" 19 17436611-17460804 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041580 Approved Uncertain "Nuclear membrane" NA NA "Nuclear membrane" "HPA041580: AB_10795700" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AIPL1 LCA4 ENSG00000129221 "Aryl hydrocarbon receptor interacting protein like 1" Q9NZN9 17 6393693-6435199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1012 "retina: 836.0" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1926.4" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;OE19: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026578 Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 79: Retina - Phototransduction" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA026578: AB_2671905" "unprognostic (2.42e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "unprognostic (1.68e-3)" "unprognostic (3.24e-1)" "unprognostic (1.13e-3)" "unprognostic (3.76e-1)" "unprognostic (5.35e-2)" 0.0 0.0 0.2 0.1 0.3 0.7 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 836.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 2.8 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.3 0.1 0.8 0.2 0.1 0.3 0.0 0.3 0.6 0.0 3.2 1.1 0.0 0.0 0.8 1.0 0.0 0.0 139.2 0.1 0.0 0.6 0.0 1.4 0.0 412.8 0.1 0.1 0.2 0.0 0.0 7.8 0.4 0.2 8.5 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.4 0.0 0.1 1.4 0.0 0.1 65.6 0.2 0.2 0.0 0.3 1.1 1.3 0.0 0.3 1.8 0.0 0.0 256.1 0.0 0.5 0.1 0.1 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1926.4 0.0 1.8 0.3 0.4 0.2 0.0 0.4 0.3 0.4 0.1 0.0 1.7 ANKRD33 "C12orf7, DKFZp686O1689, PANKY" ENSG00000167612 "Ankyrin repeat domain 33" Q7Z3H0 12 51888009-51891727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "retina: 18.3" "Group enriched" "Detected in some" 17 "Cone photoreceptor cells: 166.8;Rod photoreceptor cells: 166.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058753 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA058753: AB_2683808" "unprognostic (4.42e-2)" "unprognostic (2.13e-5)" "unprognostic (8.25e-4)" "unprognostic (2.37e-1)" "unprognostic (3.25e-5)" "unprognostic (2.42e-1)" "unprognostic (4.07e-1)" "unprognostic (6.21e-2)" "unprognostic (5.51e-10)" "unprognostic (4.41e-3)" "unprognostic (5.56e-2)" "unprognostic (2.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.4 0.0 0.0 0.0 166.8 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.1 0.0 0.0 0.0 0.0 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 96.3" "Cell type enhanced" "Detected in all" "Muller glia cells: 289.1;Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported Nucleoplasm,Centrosome NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" Centrosome Nucleoplasm "HPA036292: AB_10673618, HPA063596: AB_2685053" "unprognostic (1.36e-1)" "unprognostic (2.89e-3)" "unprognostic (4.19e-2)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (3.21e-1)" "unprognostic (3.99e-3)" "unprognostic (5.58e-2)" "prognostic favorable (1.71e-6)" "unprognostic (5.62e-2)" "unprognostic (3.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.03e-1)" 8.1 8.9 20.2 4.2 21.3 1.7 8.1 20.8 25.1 12.4 19.1 11.3 4.2 11.5 10.6 4.6 15.2 5.2 13.5 20.8 19.5 15.4 5.2 8.3 3.6 19.3 19.1 16.8 6.4 19.8 21.0 4.9 19.7 8.7 4.6 96.3 6.3 9.0 5.6 7.2 6.1 8.7 18.5 4.5 8.8 11.0 20.5 5.7 11.4 5.9 4.7 9.8 8.3 19.5 14.7 25.0 33.6 24.7 15.2 22.7 5.9 11.4 17.3 13.6 14.7 8.7 7.4 6.1 10.8 18.5 16.4 10.7 12.7 15.3 16.9 16.1 13.4 9.9 16.9 8.3 16.4 4.6 9.5 11.5 12.6 18.8 11.0 36.1 15.8 12.0 4.5 6.0 23.0 15.1 9.5 7.3 13.0 9.2 9.8 7.9 24.8 5.4 18.1 7.7 11.8 25.7 8.7 1.8 14.1 18.5 45.1 4.6 9.1 9.2 12.9 18.9 16.0 4.2 8.9 11.3 24.4 13.6 8.1 2.0 7.2 2.6 3.7 6.1 9.4 4.5 6.5 5.5 7.1 3.9 3.9 4.7 13.4 4.4 5.4 5.2 4.9 5.4 20.2 21.3 20.8 25.1 20.8 19.5 19.3 19.1 19.7 18.5 20.5 19.5 46.0 54.5 39.3 47.7 16.7 32.1 70.4 144.3 29.0 167.6 48.2 57.5 135.5 31.5 85.8 62.5 116.7 45.5 12.1 9.4 234.8 70.7 46.5 250.5 85.2 41.6 74.8 9.4 30.8 43.6 37.8 61.7 19.4 84.6 33.0 94.1 43.9 25.5 64.7 97.6 37.6 31.6 73.2 16.4 33.6 25.8 60.6 26.8 76.5 13.1 67.3 289.1 13.4 31.7 23.4 31.1 13.5 104.2 18.6 54.2 23.1 225.8 268.3 318.6 26.3 50.8 122.0 145.6 43.4 11.9 31.7 32.3 20.8 58.6 25.4 50.5 ARMS2 "ARMD8, LOC387715" ENSG00000254636 "Age-related maculopathy susceptibility 2" P0C7Q2 10 122454653-122457352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 16.9;Late spermatids: 59.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067225 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA067225: AB_2685806" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (2.61e-2)" "unprognostic (2.84e-2)" "unprognostic (3.49e-2)" "unprognostic (1.98e-2)" "unprognostic (3.47e-3)" "unprognostic (3.60e-2)" "unprognostic (5.29e-5)" "unprognostic (2.53e-2)" "unprognostic (9.46e-3)" "unprognostic (2.68e-2)" "unprognostic (5.25e-2)" 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.2 1.3 0.1 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.6 0.4 0.4 0.1 0.2 0.0 0.0 0.3 0.4 0.7 0.0 0.0 0.4 1.3 0.4 0.1 0.0 0.5 0.8 0.0 0.0 0.6 0.0 0.1 0.2 0.0 0.1 2.9 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 1.3 0.4 0.4 0.3 0.4 0.4 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 16.9 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 59.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.0 8.6 0.0 0.0 0.0 0.0 ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "retina: 392.2" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 1538.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA063129: AB_2732696" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-1)" "unprognostic (4.02e-3)" "unprognostic (2.77e-7)" "unprognostic (8.64e-2)" "unprognostic (6.53e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" 0.2 0.3 0.1 0.5 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.3 0.6 0.3 0.0 0.2 0.1 0.4 0.4 0.1 0.1 0.1 0.0 0.2 0.9 0.4 0.3 0.3 0.4 0.0 0.0 0.3 0.3 0.3 0.2 392.2 0.3 0.0 0.3 2.3 0.9 0.0 0.1 0.5 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.1 0.2 1.2 0.8 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.1 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.1 2.2 0.0 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.0 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.7 0.0 0.1 0.9 0.5 0.7 0.5 0.0 0.5 0.3 0.3 0.5 0.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.3 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 46.7 0.0 0.0 0.3 0.0 0.0 0.0 1538.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.2 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 68.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 172.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATP1B2 AMOG ENSG00000129244 "ATPase Na+/K+ transporting subunit beta 2" P14415 17 7646627-7657770 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "brain: 395.1;retina: 614.8" "Group enriched" "Detected in many" 5 "Astrocytes: 207.3;Bipolar cells: 330.2;Cone photoreceptor cells: 250.2;Muller glia cells: 303.2;Rod photoreceptor cells: 226.1" "Cancer enriched" "Detected in many" 17 "glioma: 200.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.6;HAP1: 2.9;K-562: 4.5;SuSa: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010698 Supported NA NA 160000 "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "HPA010698: AB_1845174" "unprognostic (9.39e-2)" "unprognostic (1.86e-2)" "unprognostic (3.89e-3)" "unprognostic (4.96e-3)" "unprognostic (3.90e-3)" "unprognostic (9.33e-2)" "unprognostic (4.86e-1)" "unprognostic (5.93e-2)" "unprognostic (5.43e-2)" "unprognostic (1.29e-2)" "prognostic favorable (1.05e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (4.60e-3)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (3.79e-2)" 6.1 10.1 212.3 0.9 251.6 11.4 5.0 268.1 288.8 13.3 25.8 9.1 1.2 8.8 17.4 2.2 12.3 3.6 8.6 196.9 250.0 10.1 2.7 4.2 1.7 353.9 395.1 29.5 2.5 4.5 45.3 4.5 282.6 6.6 2.7 614.8 1.9 7.5 4.3 2.3 3.5 5.5 256.3 5.0 3.8 5.5 364.8 0.8 4.6 5.3 1.1 4.6 7.7 174.7 0.0 0.0 9.6 0.4 0.3 0.2 0.1 0.1 0.0 0.3 0.2 0.4 0.0 0.3 0.2 0.1 0.2 0.3 2.9 0.2 0.1 0.1 1.2 0.2 0.1 0.1 0.1 0.0 0.9 0.5 0.0 0.3 0.0 0.1 0.0 0.2 4.5 0.5 0.0 0.2 0.2 0.3 2.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 1.8 0.0 0.1 0.0 5.7 0.1 0.2 0.0 0.1 0.7 0.0 0.2 0.4 0.1 0.0 0.9 0.2 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 212.3 251.6 268.1 288.8 196.9 250.0 353.9 395.1 282.6 256.3 364.8 174.7 8.5 0.0 0.0 207.3 1.8 1.9 0.4 0.0 1.8 330.2 2.3 6.2 3.7 2.8 0.0 0.0 250.2 0.0 1.1 6.7 0.0 0.2 0.2 0.8 8.3 7.7 0.0 49.2 2.9 0.0 0.1 5.9 7.7 0.6 0.0 1.0 11.4 0.2 0.3 18.5 38.8 2.4 2.0 0.8 0.9 2.3 18.6 1.6 0.0 7.5 0.2 303.2 0.0 45.8 1.6 0.0 0.0 46.3 0.8 0.5 0.5 0.2 0.0 226.1 26.3 2.4 50.0 1.2 6.1 1.6 1.1 0.3 1.6 0.5 2.6 0.2 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175510-112224699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.2;liver: 52.3;retina: 55.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061542 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA061542: " "unprognostic (2.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (7.60e-3)" "unprognostic (1.88e-1)" "unprognostic (3.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" 3.8 21.3 4.9 0.3 5.8 0.2 0.8 5.0 9.3 2.2 10.0 2.6 0.5 1.6 1.0 3.4 9.7 5.1 47.2 4.8 6.4 2.5 52.3 1.7 0.4 7.4 6.7 1.3 1.1 0.3 4.4 3.8 7.0 1.9 0.5 55.9 0.9 0.9 21.4 1.1 1.7 1.1 5.9 1.1 0.9 3.0 6.5 0.3 2.5 14.3 0.8 2.3 4.6 8.3 0.1 1.0 0.4 0.6 0.4 0.4 0.0 0.3 0.2 0.1 0.5 0.0 5.9 0.4 0.5 0.6 0.6 1.2 0.0 0.2 0.4 0.1 0.1 0.7 0.5 0.4 12.3 0.4 0.2 0.1 2.3 0.1 0.3 1.1 0.0 0.1 0.1 0.3 0.1 0.0 0.5 1.3 0.1 0.6 0.2 0.3 0.1 0.2 0.2 0.2 0.5 0.2 0.4 0.2 0.0 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 2.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 4.9 5.8 5.0 9.3 4.8 6.4 7.4 6.7 7.0 5.9 6.5 8.3 1.7 3.2 3.1 10.1 2.0 3.3 20.3 8.6 6.8 12.6 2.2 1.5 51.3 58.6 8.2 5.5 410.8 0.3 4.4 5.0 0.0 3.7 3.1 26.5 3.0 4.5 8.3 0.0 50.7 2.1 0.4 16.3 1.1 1.2 5.7 4.0 16.4 83.1 1.0 134.6 51.5 1.6 2.0 2.8 3.8 2.4 4.1 7.9 1.8 47.8 3.7 13.9 7.2 7.1 51.3 1.6 2.6 3.8 1.2 10.3 18.2 1.3 67.6 254.6 0.0 5.0 3.8 8.3 2.5 1.8 3.1 0.7 5.2 6.8 3.5 8.7 BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.3;brain: 41.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 272.8" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.6" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 71.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" 9.1 3.7 16.3 8.3 30.5 26.3 5.3 24.9 23.2 5.3 10.2 3.8 1.7 4.1 10.0 2.8 5.9 5.1 5.7 16.5 20.2 3.7 2.6 10.3 2.3 27.9 27.3 4.6 2.5 0.3 3.4 2.4 26.7 4.0 1.0 6.7 2.2 2.0 1.6 2.7 3.9 1.8 19.2 11.0 3.3 5.4 28.6 0.4 2.7 1.4 0.4 5.3 4.7 41.7 0.8 0.8 0.4 0.7 17.7 3.8 1.4 1.0 1.8 0.4 1.3 0.5 0.5 0.1 1.7 1.1 2.0 1.1 0.0 0.0 0.3 0.3 0.2 0.0 6.7 0.9 4.9 0.2 0.5 5.6 1.6 1.9 4.1 1.8 0.0 0.8 0.8 7.6 1.9 0.6 0.1 0.6 0.0 0.8 2.1 0.0 0.1 0.3 0.0 2.0 1.0 0.9 1.6 0.1 71.6 0.8 0.7 2.3 0.2 0.9 0.5 0.7 0.3 10.3 0.8 0.7 4.8 0.6 1.2 2.6 3.9 3.9 0.2 4.6 0.2 0.7 0.2 0.1 2.6 0.2 0.1 0.1 37.6 0.1 5.1 0.4 0.3 1.9 16.3 30.5 24.9 23.2 16.5 20.2 27.9 27.3 26.7 19.2 28.6 41.7 2.7 25.6 59.3 9.1 11.4 36.3 6.3 54.8 18.8 2.0 22.0 7.4 3.3 14.3 57.2 1.8 0.0 14.5 5.6 22.5 0.0 3.8 8.3 5.3 9.0 16.4 10.3 29.0 0.3 3.3 23.4 32.4 9.2 9.0 76.4 1.9 21.0 13.8 37.1 0.0 0.7 10.7 22.4 75.4 272.8 2.9 15.2 49.0 55.2 1.0 14.1 6.0 3.1 17.1 43.0 3.1 21.0 6.8 5.9 11.8 28.0 5.6 37.7 9.6 6.6 16.1 20.8 3.2 4.1 6.2 32.7 20.4 24.5 0.9 11.9 13.2 CABP5 CABP3 ENSG00000105507 "Calcium binding protein 5" Q9NP86 19 48029383-48044079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 509 "retina: 388.6" "Group enriched" "Detected in some" 10 "Bipolar cells: 153.8;Rod photoreceptor cells: 284.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enriched" "Detected in single" 10 "U-2197: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043698 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 18: U-2197 - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA043698: AB_10797147" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 388.6 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 153.8 0.0 0.0 0.3 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 21.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 284.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CACNA1F "AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2" ENSG00000102001 "Calcium voltage-gated channel subunit alpha1 F" O60840 X 49205063-49233371 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Transport, Vision" "Calcium channel, Ion channel, Voltage-gated channel" "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "retina: 125.3" "Group enriched" "Detected in some" 13 "Bipolar cells: 66.5;Cone photoreceptor cells: 133.5;Rod photoreceptor cells: 97.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "U-266/70: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA068379 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 79: Retina - Phototransduction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA068379: AB_2732782" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (4.25e-3)" "unprognostic (1.56e-2)" "unprognostic (8.46e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.04e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (6.08e-7)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.65e-2)" "unprognostic (3.77e-3)" 0.2 0.4 0.7 0.4 0.7 1.9 0.7 2.3 1.4 0.2 0.8 0.6 0.8 0.2 1.0 0.2 0.5 0.2 0.2 0.8 0.4 0.3 0.0 0.6 1.3 0.4 0.1 0.3 0.6 0.0 0.1 0.0 0.5 0.1 0.7 125.3 0.6 0.4 0.0 1.0 1.6 0.2 0.0 0.8 0.6 0.2 0.4 0.8 0.4 0.0 0.5 0.2 0.1 0.8 0.1 0.7 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.3 0.1 0.0 0.8 0.4 0.5 0.4 0.5 0.0 0.0 0.0 0.3 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.3 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.1 0.3 1.3 0.1 0.0 0.7 0.7 2.3 1.4 0.8 0.4 0.4 0.1 0.5 0.0 0.4 0.8 0.2 0.0 0.5 0.0 1.1 0.0 0.1 0.1 0.0 66.5 1.1 0.9 1.9 0.0 0.0 1.8 133.5 0.1 2.8 0.2 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.4 0.9 0.2 0.2 0.1 1.1 0.2 0.0 0.0 0.0 0.0 0.2 6.7 0.4 2.3 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 7.4 0.0 0.0 0.3 0.0 0.1 0.4 0.1 0.1 0.4 0.1 0.1 97.5 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.3 0.1 CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 313.8;skin 1: 214.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 379.5;Rod photoreceptor cells: 240.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cell line enhanced" "Detected in some" "HAP1: 10.2;HEK 293: 5.2;HEL: 6.3;K-562: 4.6;NTERA-2: 4.4;RPTEC TERT1: 16.3" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.0" "Low region specificity" "Detected in all" HPA036819 Enhanced "Intracellular and membrane" NA NA 55000 "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" 0.2 1.9 7.4 1.0 18.3 0.4 4.5 2.3 8.7 5.3 46.2 29.2 0.1 0.6 4.4 10.7 0.5 0.4 1.2 6.6 7.5 0.4 0.5 0.2 0.9 13.4 2.3 1.1 0.1 0.0 3.0 0.2 13.9 1.4 53.2 313.8 1.5 4.2 1.0 214.0 12.2 1.2 0.1 7.0 0.2 0.3 3.2 3.3 0.2 0.0 1.1 0.1 3.5 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 10.2 2.0 0.0 0.0 5.2 6.3 0.0 0.0 0.2 0.0 0.2 0.0 2.2 0.0 0.7 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.5 4.4 0.0 0.0 0.0 0.0 1.4 16.3 0.0 3.4 0.8 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 7.4 18.3 2.3 8.7 6.6 7.5 13.4 2.3 13.9 0.1 3.2 3.5 0.0 0.0 0.5 1.3 0.1 51.2 0.3 1.4 3.4 24.1 0.0 0.1 1.8 0.0 0.7 0.0 379.5 0.0 2.1 47.9 0.0 0.1 0.0 2.7 0.7 1.8 12.7 0.0 4.9 0.0 0.0 0.6 0.0 3.1 0.0 3.7 0.4 0.4 0.0 5.0 7.7 46.9 0.0 0.3 5.2 0.2 0.0 0.1 3.6 1.0 0.0 26.3 1.0 7.5 4.4 0.0 31.2 0.0 0.7 0.3 23.0 0.2 0.1 240.4 0.0 0.2 0.3 0.6 0.3 3.0 67.5 0.0 3.0 0.3 52.9 0.2 CFAP161 "C15orf26, FLJ38615" ENSG00000156206 "Cilia and flagella associated protein 161" Q6P656 15 81007033-81149179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 34.8;fallopian tube: 15.8" "Cell type enhanced" "Detected in some" "Early spermatids: 18.1;Endometrial ciliated cells: 26.5;Late spermatids: 5.4;Respiratory ciliated cells: 23.3;Spermatocytes: 15.6" "Cancer enriched" "Detected in some" 4 "endometrial cancer: 2.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HEL: 84.4;K-562: 29.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076975 Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "HPA076975: " "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.05e-4)" "unprognostic (1.57e-3)" "unprognostic (2.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (3.33e-2)" "unprognostic (3.13e-1)" "unprognostic (1.29e-3)" "unprognostic (8.93e-2)" "unprognostic (1.47e-1)" "unprognostic (9.24e-2)" "unprognostic (6.22e-2)" 0.4 0.1 0.8 0.1 1.2 0.6 0.2 4.3 1.1 0.6 34.8 0.1 0.0 0.6 0.6 0.1 15.8 0.2 0.6 1.2 0.6 0.3 0.2 2.7 0.1 2.5 3.5 0.1 0.2 0.3 1.7 1.3 2.0 0.1 0.0 1.3 0.2 0.2 0.2 0.5 0.1 0.2 3.0 0.5 0.2 6.4 1.2 0.0 0.6 0.8 0.2 0.2 0.1 1.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.2 0.0 0.2 0.2 0.3 0.0 84.4 0.2 0.2 0.0 0.0 11.0 0.0 0.0 0.3 1.0 0.0 1.7 0.0 29.2 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 1.2 0.2 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 1.4 0.1 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 3.4 0.8 1.2 4.3 1.1 1.2 0.6 2.5 3.5 2.0 3.0 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 26.5 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 2.8 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 23.3 0.6 0.0 0.0 0.0 15.6 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 39.3;lymphoid tissue: 65.8;retina: 53.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 164.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 356.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" 0.3 39.3 4.4 5.1 2.0 0.0 0.1 6.3 1.0 1.0 0.3 8.1 1.5 0.5 0.0 0.1 0.0 0.3 0.4 0.7 2.3 0.0 0.0 0.2 0.3 3.1 6.4 0.1 0.2 0.0 1.1 0.1 10.0 0.2 4.0 53.5 0.1 0.0 0.1 0.7 3.0 3.7 0.3 0.1 2.8 1.0 9.2 65.8 0.2 0.0 0.8 0.2 0.7 1.0 0.1 0.3 0.7 0.6 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 1.5 0.0 8.8 0.0 0.0 0.3 1.4 0.5 0.4 0.1 0.0 0.1 4.0 0.0 0.3 0.0 0.0 0.0 0.0 22.6 0.2 0.0 0.0 0.3 7.1 0.0 1.6 0.1 0.2 0.4 0.3 0.1 0.0 0.4 67.7 356.1 0.3 0.1 0.1 0.5 0.4 0.0 0.0 0.1 1.7 0.1 0.4 0.2 0.7 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.0 6.3 1.0 0.7 2.3 3.1 6.4 10.0 0.3 9.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 164.7 0.0 0.0 0.2 1.9 0.0 3.7 0.1 1.2 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.7 0.4 3.6 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.1 0.1 0.3 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.1 CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Club cells: 41.6;Gastric mucus-secreting cells: 26.5;Respiratory ciliated cells: 81.1;Skeletal myocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.6;NTERA-2: 3.6;T-47d: 7.3;THP-1: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" 11.4 0.1 1.2 4.3 0.7 0.1 11.9 2.4 1.0 15.8 235.9 4.0 2.0 2.1 2.7 2.6 11.4 8.8 11.1 11.3 0.7 2.6 0.9 9.8 1.2 3.0 4.5 4.9 3.2 28.3 3.3 0.1 2.6 9.8 2.9 0.2 25.4 7.0 1.6 6.0 3.1 0.7 1.3 1.0 138.5 0.3 4.4 8.4 13.2 4.3 3.8 12.9 5.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.9 7.3 3.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 2.4 1.0 11.3 0.7 3.0 4.5 2.6 1.3 4.4 0.7 0.3 6.4 20.7 1.3 0.0 0.6 5.1 7.3 4.0 0.0 15.6 11.0 11.4 30.0 41.6 9.2 0.0 0.0 0.2 2.2 1.9 8.0 0.1 15.1 0.3 0.4 4.9 0.0 0.3 0.9 0.0 3.7 26.5 2.2 1.3 11.8 0.0 0.0 0.1 0.0 0.6 1.4 16.2 0.0 0.4 0.3 0.3 0.4 7.2 0.0 0.6 0.0 0.0 0.0 0.1 17.2 0.6 3.0 0.4 10.2 0.1 0.2 81.1 0.0 0.0 24.0 2.4 0.2 0.2 0.6 0.4 0.0 0.4 0.0 2.8 20.4 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CNGB3 "ACHM1, ACHM3, RMCH" ENSG00000170289 "Cyclic nucleotide gated channel subunit beta 3" Q9NQW8 8 86553977-86743675 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;retina: 13.1" "Cell type enriched" "Detected in some" 13 "Cone photoreceptor cells: 158.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "SCLC-21H: 18.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057244 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA057244: AB_2683380" "unprognostic (5.35e-1)" "unprognostic (1.68e-3)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (3.62e-2)" "unprognostic (2.58e-1)" "unprognostic (6.25e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (2.17e-1)" "unprognostic (3.82e-1)" "unprognostic (9.28e-2)" "unprognostic (2.77e-4)" "unprognostic (1.40e-4)" "unprognostic (1.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.84e-1)" 0.0 0.0 0.2 0.3 0.3 4.1 0.0 1.2 0.5 0.2 1.7 0.1 0.5 0.2 0.1 0.0 0.9 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.1 0.4 0.4 0.6 0.0 0.0 0.1 0.2 0.1 0.0 13.1 0.3 0.0 0.1 1.2 0.1 0.0 0.1 0.1 0.3 2.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 1.3 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.3 0.0 1.0 18.9 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.2 0.5 0.3 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 158.4 0.1 1.3 0.0 0.0 0.0 5.6 0.1 0.6 0.2 0.0 0.0 2.4 0.0 0.0 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 11.4 0.0 0.1 0.0 1.0 0.2 1.5 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.1 1.6 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 68.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 310.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 25.7;NTERA-2: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" NA NA 120000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074749: AB_2732266" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.48e-3)" "unprognostic (5.72e-2)" "unprognostic (5.32e-4)" "unprognostic (3.24e-3)" "unprognostic (8.79e-2)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (2.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.62e-2)" 0.2 0.0 5.1 0.1 5.3 0.0 0.1 4.5 5.6 0.8 68.8 1.3 0.8 0.3 0.1 0.1 0.2 0.3 9.1 5.6 5.7 1.2 0.0 0.0 0.0 7.1 5.8 0.0 0.3 0.1 5.1 0.0 6.0 15.2 0.5 9.5 1.5 0.3 0.0 0.1 0.9 0.2 5.1 0.0 1.5 4.1 5.3 0.1 0.4 0.3 0.0 1.3 2.9 6.3 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 4.5 5.6 5.6 5.7 7.1 5.8 6.0 5.1 5.3 6.3 0.6 0.0 0.0 2.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 0.0 4.2 0.0 0.0 1.0 1.9 0.0 21.4 1.2 0.1 0.8 1.2 0.0 1.4 0.2 0.0 0.5 0.0 1.7 0.0 1.0 0.0 0.0 0.1 35.3 6.7 0.5 0.0 0.0 0.0 11.6 0.0 0.1 0.0 2.8 0.1 68.5 0.0 310.1 0.6 0.0 0.8 0.4 0.0 2.3 0.0 0.1 0.0 3.2 0.0 0.3 4.2 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.8 0.1 CPLX4 CPX-IV ENSG00000166569 "Complexin 4" Q7Z7G2 18 59275156-59318649 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 287 "retina: 314.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 74.1;Cone photoreceptor cells: 112.6;Muller glia cells: 31.8;Rod photoreceptor cells: 173.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047627 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA047627: " "unprognostic (1.85e-1)" "unprognostic (4.46e-1)" "unprognostic (4.20e-2)" "unprognostic (4.05e-2)" "unprognostic (9.90e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.1 0.0 0.0 0.3 0.0 0.0 0.0 112.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 31.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRABP1 "CRABP, CRABP-I, CRABPI, RBP5" ENSG00000166426 "Cellular retinoic acid binding protein 1" P29762 15 78340353-78348225 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 544.1;thyroid gland: 173.2" "Cell type enriched" "Detected in some" 24 "Muller glia cells: 4845.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 117.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 1022.7;NTERA-2: 307.4" "Group enriched" "Detected in many" 5 "amygdala: 6.4;basal ganglia: 23.4;hypothalamus: 13.3;olfactory bulb: 12.8;pons and medulla: 7.4" "Low region specificity" "Detected in all" HPA017203 Enhanced Supported NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA017203: AB_1846512" "unprognostic (1.23e-1)" "unprognostic (3.76e-3)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (2.01e-1)" "unprognostic (4.35e-2)" "unprognostic (1.05e-1)" "unprognostic (1.35e-1)" "unprognostic (2.45e-2)" "unprognostic (9.79e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (9.37e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (2.69e-1)" 0.9 1.7 14.2 2.5 24.8 0.2 56.1 25.6 26.4 1.3 28.5 6.9 0.8 2.3 2.0 0.6 0.3 1.6 0.4 9.6 39.6 15.5 0.0 0.7 0.2 61.7 62.6 0.4 0.7 0.0 27.6 15.0 58.4 2.6 1.7 544.1 1.1 47.4 0.2 26.7 5.0 1.8 23.8 75.2 7.1 0.5 86.2 1.7 173.2 0.2 1.2 0.6 2.5 13.7 0.0 0.2 1022.7 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 65.3 0.9 0.0 6.3 0.0 0.3 0.0 9.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 57.9 0.4 307.4 1.0 0.8 0.0 0.0 0.0 0.0 1.5 85.5 58.0 0.0 0.2 0.1 24.8 1.4 35.9 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 24.8 25.6 26.4 9.6 39.6 61.7 62.6 58.4 23.8 86.2 13.7 1.0 0.0 0.0 0.3 0.8 9.7 0.1 0.0 0.0 31.1 112.6 199.0 0.0 0.0 0.0 0.0 33.3 1.1 2.9 1.1 70.5 0.0 0.0 0.1 0.1 4.8 0.0 0.0 0.2 0.0 0.8 11.3 0.0 0.1 0.0 4.2 0.0 0.0 1.5 10.1 1.5 0.4 0.0 0.0 5.3 0.0 0.0 0.5 192.1 0.0 0.0 4845.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.4 0.5 0.0 91.2 0.0 0.0 1.0 0.1 2.2 0.0 2.6 1.4 0.9 0.0 1.6 0.1 CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 469.5;Cone photoreceptor cells: 164.7;Inhibitory neurons: 130.1;Muller glia cells: 79.7;Oligodendrocyte precursor cells: 280.0;Oligodendrocytes: 105.6;Rod photoreceptor cells: 149.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 8 "HeLa: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" 0.1 0.1 15.7 0.0 17.6 0.4 0.1 19.8 20.5 0.0 9.6 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.2 15.8 14.2 0.1 0.0 0.1 0.1 18.7 18.4 0.7 0.4 0.0 2.2 0.0 17.5 0.0 0.0 74.7 0.0 0.0 0.7 0.0 0.0 0.0 18.9 0.0 0.2 2.9 16.1 0.0 0.2 0.5 0.0 0.0 0.0 21.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 15.7 17.6 19.8 20.5 15.8 14.2 18.7 18.4 17.5 18.9 16.1 21.3 0.0 0.0 0.0 469.5 0.0 0.3 0.2 0.3 0.0 15.0 0.2 0.1 1.1 0.0 0.2 0.0 164.7 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.7 0.0 11.6 53.2 0.0 0.0 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.7 130.1 0.0 2.0 0.0 0.5 1.6 1.8 0.0 0.0 24.4 0.0 79.7 0.0 280.0 105.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.9 149.3 0.0 0.2 0.1 1.8 0.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.9;choroid plexus: 14.1;retina: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 40.5;Bipolar cells: 29.7;Cone photoreceptor cells: 118.9;Oligodendrocytes: 26.8;Rod photoreceptor cells: 110.1" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "AF22: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043674 Approved Supported "Intracellular and membrane" NA NA 210000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" 1.6 0.0 14.5 0.5 21.5 0.3 0.1 11.0 12.5 0.0 14.1 0.7 0.1 1.5 0.1 0.0 1.0 0.0 0.1 13.8 13.7 5.8 0.0 0.0 0.7 24.0 20.3 0.2 0.0 0.0 1.4 0.0 14.9 0.0 0.4 8.1 0.0 0.0 0.0 0.1 0.3 0.3 22.2 0.5 0.2 0.5 24.9 0.2 0.1 0.0 0.6 0.2 0.0 23.0 0.0 0.1 32.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.6 0.0 0.0 4.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 21.5 11.0 12.5 13.8 13.7 24.0 20.3 14.9 22.2 24.9 23.0 0.0 0.0 0.0 40.5 0.5 0.3 0.1 0.0 0.0 29.7 0.0 2.2 2.8 0.0 0.0 1.8 118.9 0.1 0.0 0.7 0.0 0.0 3.9 0.4 1.3 0.4 3.0 0.0 4.2 0.0 0.1 2.5 0.0 0.1 1.3 0.0 0.0 0.0 0.2 3.3 0.4 2.8 0.0 0.0 1.0 7.7 1.8 0.1 0.0 0.0 0.1 6.1 1.0 2.0 26.8 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 110.1 0.0 0.5 0.3 0.1 0.3 0.0 0.6 0.3 0.1 0.1 5.3 0.1 CROCC "ROLT, rootletin" ENSG00000058453 "Ciliary rootlet coiled-coil, rootletin" Q5TZA2 1 16740273-16972964 "Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021191, HPA021762" Enhanced Supported "Plasma membrane,Centrosome" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Centrosome" "HPA021191: AB_1856395, HPA021762: AB_1856396" "unprognostic (9.07e-3)" "unprognostic (9.03e-2)" "unprognostic (6.04e-2)" "prognostic favorable (8.34e-5)" "unprognostic (3.27e-1)" "unprognostic (1.25e-3)" "unprognostic (1.42e-3)" "prognostic favorable (7.92e-4)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (3.36e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (1.58e-1)" "unprognostic (9.83e-2)" "unprognostic (6.05e-2)" "unprognostic (1.76e-3)" 7.6 7.6 5.2 2.3 5.5 1.6 8.0 10.1 7.2 13.5 29.0 10.2 1.7 10.4 0.7 10.0 22.7 1.4 6.2 5.8 6.2 8.3 3.3 8.4 2.4 9.5 11.5 13.3 10.7 1.7 10.2 1.3 6.1 10.4 0.4 11.3 7.6 1.8 6.2 14.3 7.9 1.1 6.2 10.2 8.9 5.3 6.6 2.8 8.1 1.2 0.7 9.2 11.4 6.9 4.1 1.7 3.1 3.1 2.1 1.9 1.2 2.9 0.9 0.9 1.0 0.2 1.8 10.9 2.7 1.3 0.3 4.9 0.7 2.2 0.1 0.9 5.6 5.0 6.1 0.8 3.7 0.3 4.9 1.7 5.0 0.9 0.8 1.7 1.5 7.7 0.7 2.7 0.3 3.5 3.4 1.2 11.1 0.9 2.6 3.1 4.1 3.8 0.7 1.1 9.4 10.2 3.1 2.0 9.7 0.9 4.1 1.4 4.3 2.6 3.4 6.8 2.3 4.7 3.7 2.2 2.6 0.7 3.3 0.0 0.0 0.3 0.3 0.1 0.5 0.1 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 0.1 5.2 5.5 10.1 7.2 5.8 6.2 9.5 11.5 6.1 6.2 6.6 6.9 9.0 0.0 4.6 14.0 5.4 6.2 4.1 4.4 17.1 26.3 7.9 7.7 5.8 5.7 4.1 5.5 27.1 1.3 8.2 2.3 0.0 4.7 5.5 35.2 6.3 7.1 3.6 2.5 27.9 2.3 6.5 11.3 6.1 5.9 1.3 28.2 6.4 1.8 2.4 3.3 24.0 4.3 4.1 1.6 5.3 2.6 19.3 3.4 5.4 11.2 3.1 11.7 12.3 13.0 19.9 2.4 1.9 12.8 2.1 2.0 0.8 1.5 34.0 109.7 0.0 12.8 9.4 1.2 12.8 13.1 5.1 1.1 8.0 3.5 2.7 2.2 CRX "CORD2, CRD, LCA7, OTX3" ENSG00000105392 "Cone-rod homeobox" O43186 19 47819779-47843330 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Cone-rod dystrophy, Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 136 "retina: 238.5" "Group enriched" "Detected in some" 5 "Bipolar cells: 136.5;Cone photoreceptor cells: 285.7;Rod photoreceptor cells: 501.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036762, HPA036763" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA036762: AB_10673663, HPA036763: AB_10670922" "unprognostic (1.09e-2)" "unprognostic (1.25e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-2)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (3.71e-1)" "unprognostic (3.82e-2)" "unprognostic (1.33e-2)" "unprognostic (1.95e-10)" "unprognostic (9.27e-2)" "unprognostic (1.82e-2)" "unprognostic (8.94e-2)" "unprognostic (1.78e-3)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 238.5 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.3 0.6 0.1 0.1 0.2 0.0 0.1 0.3 0.8 6.4 14.3 0.0 0.6 0.9 2.3 0.1 0.0 136.5 0.3 0.4 0.5 1.5 13.6 0.0 285.7 0.2 1.7 0.1 0.0 0.0 0.7 0.5 0.5 5.5 0.0 0.0 0.4 0.0 0.2 3.9 0.0 0.8 10.1 0.1 1.8 0.5 0.2 32.0 0.3 0.2 0.0 1.0 1.8 0.5 4.7 2.2 0.0 0.0 0.2 59.3 0.0 0.0 0.1 0.0 0.0 0.7 0.3 1.3 0.2 0.0 9.7 501.5 0.0 0.9 0.3 0.2 0.6 0.0 1.1 0.0 1.3 0.1 0.1 1.7 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Early spermatids: 50.7;Late spermatids: 49.1;Leydig cells: 155.4;Sertoli cells: 85.5;Smooth muscle cells: 70.9" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HBEC3-KT: 12.6;hTERT-HME1: 16.4;HUVEC TERT2: 16.1;LHCN-M2: 37.0;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" 41.7 19.8 2.0 2.8 2.5 0.2 47.1 1.9 2.3 15.6 3.5 6.1 1.9 5.6 6.8 4.0 8.2 4.9 26.2 1.5 2.4 6.9 4.7 2.9 14.2 3.2 4.2 23.7 3.1 4.0 5.8 51.6 3.6 14.2 3.2 66.7 6.9 20.6 72.0 5.9 4.7 6.7 1.6 9.8 3.4 15.0 3.6 20.4 9.0 121.2 9.1 7.7 13.0 2.5 3.2 0.0 6.5 0.2 0.8 0.2 0.0 2.9 0.0 0.5 0.1 0.0 0.0 0.1 10.2 0.1 0.1 0.0 0.0 12.6 0.0 0.0 1.6 0.0 6.1 0.0 2.8 0.0 0.1 5.4 0.0 0.1 16.4 0.0 16.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.9 0.0 3.7 0.1 1.3 0.0 0.2 0.0 0.1 15.6 0.6 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.9 2.3 1.5 2.4 3.2 4.2 3.6 1.6 3.6 2.5 11.4 0.0 0.0 0.3 0.0 2.7 0.3 0.0 0.0 1.3 2.4 9.8 2.6 0.0 0.0 0.0 120.9 0.3 0.4 0.0 3.9 0.5 50.7 0.2 3.2 5.4 0.0 0.0 0.6 1.0 0.5 17.8 0.0 0.3 0.0 1.6 1.4 0.0 0.7 0.0 0.9 0.0 0.0 0.0 4.2 49.1 155.4 0.6 5.4 1.9 0.0 3.4 0.0 1.0 0.1 1.3 0.0 30.9 0.0 0.2 0.0 6.5 0.0 33.1 85.5 22.0 70.9 9.8 3.3 0.3 2.0 0.5 0.4 23.5 0.0 0.3 FMN1 "DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289" ENSG00000248905 "Formin 1" Q68DA7 15 32765544-33194714 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;retina: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 117.0;Cone photoreceptor cells: 221.0;Excitatory neurons: 439.4;Inhibitory neurons: 340.0" "Cancer enriched" "Detected in many" 9 "melanoma: 14.5" "Region enriched" "Detected in some" 7 "cerebral cortex: 16.9" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 21.4;RH-30: 26.9;SK-MEL-30: 28.7;T-47d: 24.8;U-138 MG: 17.2;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005465, HPA046786" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA005465: AB_1859515, HPA046786: AB_10963545" "unprognostic (1.57e-1)" "unprognostic (5.92e-3)" "unprognostic (1.96e-1)" "unprognostic (2.10e-3)" "unprognostic (3.67e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-2)" "unprognostic (2.84e-2)" "unprognostic (3.44e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "unprognostic (2.89e-2)" "unprognostic (3.73e-1)" "unprognostic (4.32e-1)" "unprognostic (7.61e-2)" 1.8 0.8 0.0 2.4 0.0 1.2 3.0 0.0 16.9 5.3 0.0 5.7 1.3 1.0 0.7 2.0 3.1 2.4 0.9 0.0 0.0 2.8 0.5 3.4 0.9 2.3 0.0 0.2 1.2 1.4 3.7 3.7 0.0 1.8 4.4 30.0 4.2 1.2 0.7 4.2 1.8 2.2 0.0 1.0 7.9 10.2 1.7 3.8 2.5 0.5 0.6 1.3 3.6 0.0 3.8 4.0 0.8 0.4 0.1 0.4 4.9 5.4 4.1 1.5 4.0 0.6 5.0 0.6 1.8 6.1 3.4 3.7 0.1 3.7 3.9 0.0 0.2 3.1 0.8 0.4 0.2 0.0 0.2 1.5 0.2 7.9 0.1 3.1 0.0 0.1 0.0 21.4 8.8 3.9 0.1 0.0 1.1 7.0 0.3 0.6 26.9 4.9 1.8 1.5 0.3 0.9 0.0 3.3 28.7 0.9 24.8 0.0 4.9 17.2 2.7 17.9 1.6 0.0 0.0 0.9 7.3 0.2 10.1 1.3 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 2.3 0.0 0.0 0.0 1.7 0.0 0.4 41.7 46.9 10.1 1.6 3.7 3.2 2.0 3.4 117.0 7.7 5.1 3.1 14.3 17.3 0.0 221.0 12.0 5.4 13.3 11.7 5.7 16.5 17.4 2.4 2.7 9.0 0.4 439.4 1.8 5.9 2.6 97.9 7.0 24.0 1.8 0.0 0.4 10.9 47.1 340.0 16.8 16.2 28.0 3.9 12.8 0.9 29.6 33.8 64.6 5.8 6.9 0.0 8.0 61.9 11.4 11.4 0.7 2.2 4.5 4.0 1.6 29.4 102.4 0.0 13.0 1.0 18.4 16.0 7.3 3.4 18.3 5.0 0.1 9.9 5.7 FSCN2 "RFSN, RP30" ENSG00000186765 "Fascin actin-bundling protein 2, retinal" O14926 17 81528377-81537130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 4.5;retina: 8.7" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 25.0;Exocrine glandular cells: 12.0;Rod photoreceptor cells: 25.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.9;T-47d: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079270 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA079270: " "unprognostic (3.50e-3)" "unprognostic (6.55e-2)" "unprognostic (2.73e-4)" "unprognostic (1.08e-3)" "unprognostic (1.11e-2)" "unprognostic (2.11e-2)" "unprognostic (6.49e-3)" "unprognostic (3.49e-1)" "unprognostic (1.64e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (3.21e-1)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (1.74e-1)" "unprognostic (2.11e-1)" 0.2 0.2 0.4 0.2 0.5 0.1 0.5 1.2 0.6 1.1 0.2 0.5 0.2 1.3 0.5 0.6 0.8 0.1 0.3 0.1 0.2 0.9 0.1 0.5 0.2 1.0 0.3 0.9 4.5 2.0 1.0 0.1 0.4 0.8 0.1 8.7 1.8 0.4 0.1 0.5 0.5 0.1 0.6 0.6 0.8 0.5 0.3 0.1 4.2 0.1 0.2 0.3 0.5 0.5 0.7 0.4 0.3 0.5 0.1 0.0 0.5 0.3 0.5 0.0 0.0 0.4 0.5 0.5 1.9 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.4 0.0 0.4 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.5 0.0 0.9 0.0 0.2 0.1 0.4 0.1 0.3 0.2 0.2 0.2 0.2 0.5 0.0 0.0 0.0 0.6 0.3 2.0 0.0 0.6 0.6 0.1 0.1 0.2 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.2 0.6 0.1 0.2 1.0 0.3 0.4 0.6 0.3 0.5 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 3.8 0.6 0.4 0.9 0.0 0.0 0.0 25.0 0.1 0.0 0.1 1.9 0.4 0.5 0.1 0.1 0.2 0.0 0.0 0.7 12.0 0.5 0.1 1.1 0.1 0.0 0.5 0.0 0.0 0.1 3.3 0.9 0.0 0.0 0.0 0.0 3.2 0.3 0.3 0.0 0.0 1.0 4.9 0.0 3.5 0.3 3.0 0.1 0.0 0.2 0.1 0.3 0.1 0.0 25.7 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.8 0.1 0.1 0.2 0.0 GNAT1 CSNBAD3 ENSG00000114349 "G protein subunit alpha transducin 1" P11488 3 50191610-50197696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 904 "retina: 1120.2" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 2275.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "hippocampal formation: 6.5" "Not detected" "Not detected" HPA045393 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA045393: AB_2679310" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (8.56e-3)" "unprognostic (3.32e-2)" "unprognostic (2.13e-1)" "unprognostic (7.72e-2)" "unprognostic (2.82e-3)" "unprognostic (6.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.87e-1)" "unprognostic (3.02e-1)" "unprognostic (9.48e-3)" 0.1 0.1 0.3 0.1 0.2 0.7 0.2 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 1120.2 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.1 1.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.9 0.4 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 222.9 0.1 0.1 0.4 0.0 0.0 0.0 241.8 0.0 0.0 0.0 0.0 0.0 14.1 0.1 0.1 13.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 90.9 0.0 0.0 0.0 0.0 0.0 38.2 0.6 0.0 0.0 0.0 0.0 397.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2275.4 0.0 0.0 0.0 4.7 2.1 0.7 0.0 0.1 0.0 0.1 0.1 0.1 GNG13 "G(gamma)13, h2-35" ENSG00000127588 "G protein subunit gamma 13" Q9P2W3 16 798041-800734 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 37 "brain: 47.4;retina: 55.8" "Cell type enriched" "Detected in some" 16 "Bipolar cells: 311.6" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 7 "cerebellum: 47.4;thalamus: 23.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 10.4;HEK 293: 9.0;HeLa: 6.5;MCF7: 12.9" "Region enhanced" "Detected in all" "cerebellum: 940.0" "Group enriched" "Detected in many" 6 "cerebellum: 37.7;olfactory bulb: 14.0" HPA046272 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "HPA046272: AB_10960062" "unprognostic (1.84e-1)" "unprognostic (2.75e-1)" "unprognostic (3.78e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-2)" "unprognostic (5.41e-2)" "unprognostic (8.47e-2)" "unprognostic (9.16e-3)" "unprognostic (4.04e-2)" "unprognostic (1.78e-1)" "unprognostic (6.77e-2)" "unprognostic (7.12e-2)" "unprognostic (1.55e-1)" "unprognostic (3.38e-1)" 0.0 0.0 3.8 0.1 1.2 0.2 0.0 47.4 4.6 0.0 0.0 0.9 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 55.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.3 23.2 0.6 0.0 0.0 0.1 0.0 0.0 4.8 0.2 3.6 0.5 1.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 10.4 0.3 1.1 0.3 0.0 0.1 1.6 0.0 0.0 0.0 1.2 9.0 1.3 6.5 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.8 0.0 12.9 1.3 0.7 1.2 0.1 1.0 2.8 2.8 0.6 0.0 1.5 0.9 0.8 0.9 0.3 0.2 0.3 0.7 0.1 0.0 1.3 1.2 1.7 0.3 0.4 2.5 4.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 1.2 47.4 4.6 0.2 2.4 0.0 4.5 1.9 0.0 23.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 311.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 5.3 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.5 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 GNGT1 GNG1 ENSG00000127928 "G protein subunit gamma transducin 1" P63211 7 93591573-93911265 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 644 "retina: 1902.1" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 3097.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 9.4;HeLa: 3.4;SK-BR-3: 3.0;SuSa: 4.3;T-47d: 5.3;U-266/84: 4.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042721 Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 79: Retina - Phototransduction" "Cluster 38: EFO-21 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA042721: AB_10806370" "unprognostic (1.30e-1)" "unprognostic (2.55e-4)" "unprognostic (3.32e-4)" "unprognostic (5.01e-2)" "unprognostic (2.54e-2)" "unprognostic (1.84e-1)" "unprognostic (3.73e-2)" "unprognostic (4.55e-1)" "unprognostic (2.23e-4)" "unprognostic (1.40e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.9 0.2 0.0 0.0 1902.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 9.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.0 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.4 0.1 1.4 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.4 0.2 1.3 2.6 1.0 0.1 3.0 0.0 4.3 5.3 0.1 0.1 0.0 2.7 0.1 0.0 2.8 4.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.2 0.1 0.6 0.1 0.0 0.2 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 371.1 0.0 0.0 0.1 0.0 0.7 0.0 385.7 0.5 0.0 0.1 1.9 0.4 0.1 0.2 0.0 21.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.2 198.5 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 619.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.8 3097.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 0.0 0.1 0.0 0.0 GNGT2 GNG9 ENSG00000167083 "G protein subunit gamma transducin 2" O14610 17 49202791-49210574 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 157.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 73.0;Kupffer cells: 26.5;NK-cells: 52.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 66.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 64.8;HDLM-2: 54.5;HUVEC TERT2: 19.4;RH-30: 21.6;TIME: 19.9;U-698: 18.2" "Low region specificity" "Detected in all" HPA043381 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA043381: AB_2678455" "unprognostic (9.11e-2)" "unprognostic (4.09e-3)" "unprognostic (1.99e-2)" "unprognostic (4.62e-5)" "unprognostic (1.34e-1)" "unprognostic (3.20e-3)" "unprognostic (1.75e-1)" "unprognostic (7.37e-2)" "unprognostic (1.30e-2)" "unprognostic (2.11e-2)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (1.23e-1)" 3.1 2.6 2.7 7.7 3.0 2.5 1.8 3.4 4.0 2.3 3.0 2.9 3.5 2.4 0.6 2.7 2.0 4.5 3.0 2.7 3.7 4.4 3.4 7.2 14.1 3.9 3.2 1.5 1.6 1.0 1.2 2.7 3.7 2.1 3.8 157.0 1.1 1.3 0.9 0.9 5.2 3.7 3.4 19.9 2.4 0.8 3.3 5.5 2.4 2.7 18.4 3.3 1.6 4.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.5 1.0 0.9 0.3 0.0 64.8 0.7 0.1 0.0 0.0 0.0 0.1 4.6 54.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 19.4 8.8 0.0 0.4 1.5 0.0 4.6 3.6 0.6 0.0 0.0 12.0 21.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 19.9 0.0 12.6 0.0 0.1 0.2 2.9 18.2 0.3 0.2 0.0 0.1 8.8 1.1 30.4 47.3 27.3 3.7 4.6 21.1 20.3 4.5 2.9 11.7 1.9 26.7 66.7 1.9 3.4 12.7 2.7 3.0 3.4 4.0 2.7 3.7 3.9 3.2 3.7 3.4 3.3 4.6 4.5 0.0 1.1 0.0 4.6 0.4 0.0 0.0 0.0 2.7 0.2 0.3 0.8 0.0 0.6 0.0 73.0 0.0 15.5 0.0 3.9 0.0 1.1 0.1 0.1 5.2 0.0 8.0 0.2 0.0 0.1 0.8 0.5 0.1 0.0 0.1 2.5 0.1 11.1 0.0 0.4 0.0 0.0 26.5 2.0 8.2 0.6 13.6 0.0 1.0 9.5 5.9 52.5 0.0 0.1 0.0 0.0 0.0 3.5 0.1 0.0 0.2 0.0 14.8 6.6 0.1 0.3 0.1 0.1 0.0 0.1 0.3 11.4 0.4 0.0 0.0 GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.2;pituitary gland: 3.5;retina: 3.2" "Group enriched" "Detected in some" 5 "Bipolar cells: 18.9;Cone photoreceptor cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007326, HPA026088" Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" "HPA007326: AB_1849308, HPA026088: AB_10602323" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.51e-2)" "unprognostic (3.63e-3)" "unprognostic (2.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.46e-4)" "unprognostic (3.27e-1)" "unprognostic (4.08e-4)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (6.72e-2)" "unprognostic (3.85e-2)" 0.0 0.7 1.2 0.0 1.7 0.0 0.0 0.2 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.3 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.7 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 0.2 3.2 1.3 0.3 0.1 0.4 0.0 0.0 1.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 18.9 0.2 0.0 0.6 0.0 0.0 0.0 6.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.7 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 1.5 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667219-113737736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "retina: 42.6" "Group enriched" "Detected in some" 16 "Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 84.9" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "retina: 11.3" "Cell type enriched" "Detected in some" 73 "Cone photoreceptor cells: 329.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA075093: , HPA078232: " "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 3.9 0.1 0.4 0.2 0.0 0.6 1.0 0.1 0.1 0.2 0.0 0.0 0.0 329.4 0.0 0.2 0.0 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 2.4 0.0 0.1 0.0 1.9 0.1 1.1 0.0 4.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.3 0.1 0.0 GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178977587-178996206 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "retina: 42.6" "Cell type enriched" "Detected in some" 31 "Bipolar cells: 440.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 56: Bipolar cells - Visual perception" "HPA014511: AB_2669025" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-1)" "unprognostic (2.25e-3)" "unprognostic (7.72e-2)" "unprognostic (2.32e-2)" "unprognostic (2.12e-3)" "unprognostic (6.27e-2)" "unprognostic (3.34e-4)" "unprognostic (2.58e-1)" "unprognostic (3.36e-4)" "unprognostic (1.23e-1)" "unprognostic (6.45e-2)" "unprognostic (7.59e-3)" "unprognostic (1.97e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.3 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.3 0.1 0.0 440.5 0.1 0.0 1.9 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 1.0 0.2 0.4 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 3.3 0.4 0.0 0.0 0.0 0.9 1.1 0.0 0.1 0.0 0.0 0.6 4.2 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 14.2 0.0 0.3 0.2 0.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42155406-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 91 "retina: 804.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 667.2;Late spermatids: 432.4;Muller glia cells: 219.9;Rod photoreceptor cells: 1191.6" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.9" "Group enriched" "Detected in some" 8 "NTERA-2: 3.8;SH-SY5Y: 4.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA005561: AB_2667361, HPA075056: " "unprognostic (1.91e-2)" "unprognostic (3.92e-3)" "unprognostic (2.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.04e-4)" "unprognostic (9.70e-2)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (3.08e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" 0.0 0.0 1.5 0.1 3.5 0.1 0.0 0.9 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 5.4 0.0 0.0 0.0 0.1 1.5 1.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 804.8 0.0 0.0 0.1 0.1 0.1 0.1 0.8 0.0 0.0 8.8 6.2 0.0 0.0 0.0 0.2 0.0 0.1 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.0 0.0 4.9 0.0 0.0 1.5 3.5 0.9 1.8 1.3 5.4 1.5 1.4 1.4 0.8 6.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 140.7 0.0 0.0 0.3 0.0 0.0 0.0 667.2 0.6 1.3 0.0 0.0 0.0 106.5 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 65.6 1.0 0.0 4.1 0.0 0.0 432.4 1.8 0.1 0.0 0.0 5.2 219.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 1191.6 0.0 0.0 1.2 3.2 3.9 0.0 0.0 0.3 0.0 0.1 0.0 0.1 GUCA1B "GCAP2, RP48" ENSG00000112599 "Guanylate cyclase activator 1B" Q9UMX6 6 42183284-42194956 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 99 "retina: 466.0" "Group enriched" "Detected in some" 4 "Astrocytes: 23.2;Cone photoreceptor cells: 83.4;Oligodendrocytes: 28.2;Rod photoreceptor cells: 53.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 4.3;U-698: 3.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA055479 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA055479: AB_2732598" "unprognostic (1.61e-1)" "unprognostic (3.28e-1)" "unprognostic (1.14e-6)" "unprognostic (5.39e-2)" "unprognostic (1.73e-2)" "unprognostic (2.87e-3)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (5.57e-1)" "unprognostic (1.66e-1)" "unprognostic (1.72e-2)" "unprognostic (3.28e-7)" "unprognostic (4.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.76e-2)" "unprognostic (2.59e-3)" 1.5 0.9 3.5 0.8 3.6 1.3 1.4 3.8 4.1 2.3 2.2 1.3 0.3 1.9 1.0 0.8 2.3 0.2 1.6 3.2 3.2 1.0 1.9 1.1 0.7 3.3 3.2 2.7 0.9 0.2 1.0 0.4 3.6 1.5 0.5 466.0 1.1 0.5 2.6 2.8 1.4 1.0 3.0 2.1 0.8 2.6 3.5 1.0 1.0 0.9 0.9 1.1 1.4 4.6 0.1 0.6 1.3 0.5 1.0 0.9 0.3 0.5 0.8 0.8 0.7 1.1 0.4 1.6 0.8 0.1 0.2 0.4 1.4 0.2 1.4 1.3 0.6 0.4 0.1 0.2 0.4 1.5 0.5 0.3 4.3 0.8 1.1 0.4 0.1 1.2 1.0 1.5 0.2 1.3 0.6 1.0 0.0 0.3 0.3 0.2 0.8 0.1 0.8 0.5 0.6 0.9 0.0 0.2 0.1 0.2 0.1 0.9 0.0 0.2 1.7 0.6 0.7 2.7 1.3 3.9 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.5 3.6 3.8 4.1 3.2 3.2 3.3 3.2 3.6 3.0 3.5 4.6 0.2 0.0 0.0 23.2 0.0 0.3 0.1 0.0 0.0 4.0 0.2 0.1 0.3 0.0 0.0 0.0 83.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.3 0.3 0.0 0.0 8.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 6.7 11.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.8 2.8 0.1 8.1 0.0 11.6 28.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 53.0 0.0 0.5 0.4 0.5 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 HCN1 "BCNG-1, BCNG1, HAC-2" ENSG00000164588 "Hyperpolarization activated cyclic nucleotide gated potassium channel 1" O60741 5 45254948-45696498 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 7.2;retina: 17.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 671.7;Inhibitory neurons: 766.5;Rod photoreceptor cells: 199.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019195 Enhanced NA NA "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019195: AB_2670094" "unprognostic (1.30e-1)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (6.82e-2)" "unprognostic (1.10e-1)" "unprognostic (9.63e-3)" "unprognostic (4.11e-3)" "unprognostic (6.78e-2)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (3.68e-3)" 0.0 0.4 1.8 0.0 2.5 0.1 0.0 2.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.5 2.4 7.2 2.5 1.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 24.5 0.0 0.1 0.1 0.0 0.0 29.4 0.0 0.0 7.4 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 671.7 0.7 0.0 0.6 0.0 0.1 0.0 0.6 0.0 0.0 0.0 6.7 766.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.5 0.0 14.8 0.0 21.1 14.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 199.4 0.0 0.3 0.1 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 267 "retina: 670.7" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 673.5;Rod photoreceptor cells: 694.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.2" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Not detected" "Not detected" "HPA027142, HPA030332, HPA030333" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA027142: AB_2672132, HPA030332: AB_2673432, HPA030333: AB_2673433" "unprognostic (6.65e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.49e-3)" "unprognostic (5.97e-2)" "unprognostic (3.56e-3)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-3)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (6.01e-2)" "unprognostic (1.96e-2)" 0.3 0.1 0.5 0.0 2.5 0.0 0.5 1.0 1.4 0.3 0.8 0.3 1.0 0.2 0.0 0.2 0.1 0.4 0.2 0.5 0.4 0.6 0.2 0.6 0.1 0.6 0.6 0.1 1.8 0.0 0.3 0.2 0.6 0.2 0.0 670.7 0.5 0.0 0.2 1.4 0.8 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.4 0.0 0.0 0.2 0.3 1.6 0.6 0.0 0.8 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 1.0 1.4 0.5 0.4 0.6 0.6 0.6 0.1 0.6 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 53.2 0.0 0.0 0.2 0.0 0.0 0.0 673.5 0.2 0.0 0.0 3.9 0.0 1.9 0.2 0.0 3.0 0.0 0.0 1.6 0.0 9.4 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 30.3 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 85.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 694.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "retina: 305.4" "Group enriched" "Detected in some" 18 "Cone photoreceptor cells: 517.1;Rod photoreceptor cells: 329.1" "Cancer enriched" "Detected in single" 12 "ovarian cancer: 2.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA008779: AB_2668138, HPA015907: AB_2669323" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.80e-5)" "unprognostic (6.66e-4)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.59e-2)" "unprognostic (7.51e-3)" "unprognostic (1.28e-1)" "unprognostic (4.50e-9)" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (6.08e-2)" 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.1 1.7 0.1 0.0 0.1 0.1 0.0 9.6 0.1 0.1 0.2 1.1 0.3 0.0 0.0 0.2 0.9 0.3 0.1 0.1 0.0 0.1 0.0 1.1 0.1 0.1 305.4 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 1.1 0.9 0.3 1.1 0.2 0.3 0.2 0.3 0.0 0.0 5.9 0.4 0.1 0.0 0.1 0.0 22.8 0.1 0.5 0.6 0.0 0.1 0.0 517.1 0.0 0.3 0.0 1.9 0.1 0.3 0.7 0.5 2.4 0.0 0.0 7.5 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.1 13.5 14.0 0.0 0.0 0.3 0.0 0.0 0.6 0.3 0.0 4.7 1.2 23.4 0.0 8.5 2.6 0.1 0.0 0.7 0.6 0.1 0.0 0.0 0.5 329.1 0.0 0.6 0.3 0.1 0.3 0.0 0.3 0.0 0.2 1.2 0.0 0.0 IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 155.3;Spermatogonia: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 131.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" 11.6 11.2 9.6 14.7 10.0 20.4 23.1 11.0 10.5 15.7 10.8 13.0 12.0 15.5 19.7 12.5 16.6 12.1 9.7 10.1 10.1 12.2 8.9 12.3 24.3 9.7 9.5 17.9 18.3 13.9 15.3 11.5 9.5 15.9 16.2 18.9 15.6 15.5 11.4 15.5 14.1 11.8 9.7 18.3 12.3 28.9 10.4 22.1 10.5 5.7 25.7 14.2 13.7 11.0 38.3 10.1 48.9 55.5 7.5 11.6 57.2 17.4 10.8 19.7 23.8 33.6 18.1 76.8 23.9 10.1 30.2 28.7 30.5 14.5 29.3 15.1 23.8 51.2 22.2 28.7 20.0 64.1 14.8 7.4 27.2 13.7 30.3 10.2 15.2 32.4 31.0 27.9 22.3 19.3 41.7 44.5 40.1 22.6 18.1 40.4 23.4 24.9 11.4 16.9 26.0 20.9 17.3 12.2 31.3 16.0 10.8 49.4 12.9 18.5 22.4 9.1 23.4 66.4 44.9 131.2 17.9 29.0 17.1 3.2 6.6 11.7 7.2 12.3 10.5 22.8 9.8 9.0 9.6 21.6 11.5 7.2 2.8 12.2 14.1 8.7 11.7 6.4 9.6 10.0 11.0 10.5 10.1 10.1 9.7 9.5 9.5 9.7 10.4 11.0 15.8 6.4 15.0 48.3 28.4 18.9 19.2 20.0 19.9 15.2 19.6 17.3 8.4 11.5 26.5 11.0 27.1 26.6 21.9 7.7 3.9 11.1 3.7 31.1 12.7 11.2 7.2 21.5 60.1 12.9 8.2 15.4 11.7 12.6 8.8 21.9 6.8 6.2 10.5 13.5 66.8 8.6 20.3 9.8 14.1 7.4 15.5 11.3 14.2 51.5 15.8 12.8 17.5 49.3 59.5 13.9 8.2 13.5 45.2 15.7 7.9 7.5 69.2 27.7 13.1 17.8 15.9 155.3 96.5 16.2 20.6 14.1 19.9 8.4 11.9 16.3 ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9;choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 376.2;Glandular and luminal cells: 551.9;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 133 "basophil: 16.5" "Lineage enriched" "Detected in single" 133 "granulocytes: 16.5" "Cell line enhanced" "Detected in many" "AF22: 44.3;EFO-21: 54.6;RPTEC TERT1: 88.1;WM-115: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" 3.8 2.6 25.7 4.2 41.8 0.3 9.6 53.9 19.2 15.4 39.4 3.7 3.2 7.7 14.0 6.4 7.5 8.7 2.9 19.5 37.5 21.6 0.8 2.4 0.5 38.9 48.4 4.7 13.3 5.1 5.4 5.2 42.7 6.7 2.8 4.6 13.6 9.0 0.2 6.3 4.2 3.0 39.7 0.0 4.2 6.5 35.6 0.8 2.1 0.9 6.9 7.2 9.0 48.6 28.2 1.1 44.3 5.6 3.7 15.2 0.0 0.1 0.5 0.2 1.5 0.3 6.9 0.0 54.6 2.0 1.7 30.1 1.9 4.5 0.5 0.0 0.7 0.0 23.1 0.0 1.8 0.0 0.1 1.8 12.6 0.5 2.4 27.1 2.4 0.0 0.0 8.3 0.8 0.1 0.0 0.0 3.3 0.4 4.8 0.0 3.7 0.0 88.1 2.5 0.7 1.9 8.6 0.2 23.5 0.8 0.7 0.1 3.0 11.2 7.1 3.2 5.8 10.2 0.1 0.0 2.7 0.0 127.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 25.7 41.8 53.9 19.2 19.5 37.5 38.9 48.4 42.7 39.7 35.6 48.6 0.7 12.8 4.8 106.4 2.5 33.1 117.2 39.4 34.7 13.3 26.3 18.7 3.0 38.6 57.9 38.6 0.0 20.0 0.4 5.0 7.9 26.3 3.0 376.2 150.6 5.2 34.0 0.0 28.1 17.4 1.2 15.5 7.7 551.9 1.3 0.9 1.4 0.2 3.3 1.7 8.2 7.4 34.6 1.0 4.7 6.5 44.1 9.8 3.6 4.7 31.6 24.3 0.0 192.0 119.2 35.8 6.1 44.8 2.0 149.7 14.5 76.7 100.1 1.4 0.0 4.8 7.0 1.4 1.1 34.6 12.4 4.9 5.5 1.9 9.6 150.7 KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 113.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 115.6;Cone photoreceptor cells: 212.7;Excitatory neurons: 150.6;Inhibitory neurons: 89.9;Rod photoreceptor cells: 386.9" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;CACO-2: 2.2;HL-60: 1.1;hTCEpi: 1.2;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" 10.7 1.5 4.3 0.3 6.6 0.0 2.8 0.0 17.8 1.2 0.0 6.2 0.2 7.3 0.8 1.7 6.0 0.6 1.2 6.6 0.0 0.3 2.4 0.3 0.0 0.0 0.0 0.4 0.3 0.2 2.7 0.1 0.0 2.2 0.6 113.3 1.6 3.1 7.3 0.5 2.0 5.0 0.0 0.3 3.4 0.4 0.0 0.1 0.1 4.4 0.0 3.8 0.9 7.9 0.0 0.0 0.3 0.0 1.4 0.1 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.9 0.7 0.6 0.9 0.0 0.0 0.7 0.0 0.0 0.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.6 0.0 17.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 7.9 20.2 0.0 2.2 7.8 0.5 0.8 0.2 0.0 0.0 115.6 0.9 0.5 3.4 1.5 0.7 0.0 212.7 0.0 0.4 0.0 0.0 0.0 0.7 19.8 2.9 8.0 0.0 0.0 150.6 0.0 0.0 1.4 0.0 4.2 3.8 1.5 0.0 5.7 0.1 18.5 89.9 0.0 0.0 0.0 0.3 0.8 4.4 0.4 0.0 12.2 0.0 38.2 0.0 43.2 3.3 0.1 0.0 34.6 0.1 0.1 0.0 0.2 4.0 386.9 0.0 0.9 7.0 0.2 0.5 0.2 0.3 0.1 0.4 0.2 0.0 0.1 KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 47.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 79.6;Excitatory neurons: 48.2;Inhibitory neurons: 120.2" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.2;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "HeLa: 1.6;RH-30: 3.7;SCLC-21H: 3.5;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" 0.1 0.8 1.1 0.1 3.3 0.9 0.2 41.0 47.3 0.9 0.0 0.3 0.3 0.3 0.0 0.2 0.1 0.2 0.1 4.5 8.0 0.1 0.2 0.1 0.2 8.8 3.0 0.2 0.4 0.0 2.2 0.0 9.3 0.2 0.0 7.0 0.3 0.0 0.5 0.5 0.3 0.0 1.0 0.2 0.3 1.4 12.3 0.1 0.3 1.2 0.0 0.3 0.5 18.8 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.1 0.2 1.1 0.3 1.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.4 3.7 0.4 0.0 0.2 3.5 2.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 1.0 0.1 0.0 0.2 0.3 0.4 0.2 0.2 0.4 3.2 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.2 0.0 0.5 0.2 0.2 1.4 0.2 0.3 0.3 0.1 0.1 1.1 3.3 41.0 47.3 4.5 8.0 8.8 3.0 9.3 1.0 12.3 18.8 0.2 0.0 0.0 5.5 1.1 0.0 0.2 0.0 0.0 79.6 0.3 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 9.5 0.2 0.5 0.4 7.7 0.0 48.2 0.2 0.0 0.3 0.0 0.3 0.0 2.8 0.0 0.0 0.0 1.7 120.2 0.0 0.0 0.0 0.0 10.2 0.3 0.2 0.0 7.5 0.6 1.5 0.0 16.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.2 0.5 6.1 5.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717510-2730037 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 289.1" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 515.0;Rod photoreceptor cells: 530.1" "Cancer enriched" "Detected in single" 78 "testis cancer: 6.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA031131: AB_10609996" "unprognostic (5.06e-2)" "unprognostic (1.47e-3)" "unprognostic (3.45e-3)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.12e-3)" "unprognostic (5.38e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.35e-1)" "unprognostic (7.96e-8)" "unprognostic (3.01e-1)" "unprognostic (4.90e-2)" "unprognostic (9.90e-2)" "unprognostic (1.06e-2)" 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.1 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.9 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 289.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.1 1.3 0.9 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.0 0.2 0.0 0.0 0.0 515.0 0.0 0.0 0.0 0.0 0.0 81.5 0.0 0.0 2.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 1.3 0.0 0.0 0.0 0.0 25.3 0.6 0.0 0.0 0.0 0.0 69.1 0.0 0.5 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 530.1 13.1 0.0 0.0 7.4 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRIT2 "AC022389.4, LRRC22" ENSG00000204033 "Leucine rich repeat, Ig-like and transmembrane domains 2" A6NDA9 10 84220571-84225544 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "retina: 59.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.5;Cone photoreceptor cells: 8.4;Rod photoreceptor cells: 24.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA037788 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA037788: AB_10672393" "unprognostic (3.12e-1)" "unprognostic (1.09e-3)" "unprognostic (3.99e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 59.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "retina: 17.6" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 33.3;Muller glia cells: 10.2;Rod photoreceptor cells: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" 0.2 0.2 0.4 0.0 0.5 0.1 0.3 0.3 0.6 0.4 0.2 0.2 0.0 0.2 0.3 0.2 0.3 0.0 0.1 0.4 0.2 0.7 0.3 0.2 0.1 0.3 0.3 0.2 0.3 0.0 0.2 0.0 0.4 0.3 0.0 17.6 0.2 0.1 0.3 0.6 0.2 0.0 0.2 0.3 0.2 0.5 0.3 0.1 0.3 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.0 0.0 33.3 0.0 0.0 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 10.2 0.0 0.5 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MLANA MART1 ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 42.9" "Cell type enriched" "Detected in some" 23 "Melanocytes: 1718.2" "Cancer enriched" "Detected in single" 556 "melanoma: 277.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 406 "SK-MEL-30: 703.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000057, HPA048662" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "CAB000057: AB_442107, HPA048662: AB_2680485" "unprognostic (2.52e-2)" "unprognostic (6.87e-2)" "unprognostic (5.20e-2)" "unprognostic (5.61e-2)" "unprognostic (2.58e-2)" "unprognostic (1.46e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-3)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (8.01e-2)" "unprognostic (5.78e-2)" "unprognostic (9.43e-2)" 0.1 0.2 0.3 0.4 0.5 0.7 1.4 2.0 0.6 0.1 5.9 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.3 0.4 0.1 0.4 0.5 0.3 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.3 1.1 0.0 0.3 42.9 0.1 0.0 0.1 0.2 0.2 0.3 0.6 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.8 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.2 1.7 1.3 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.3 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.1 0.4 0.1 703.0 0.1 0.1 0.3 0.6 0.2 0.4 0.1 0.7 0.2 0.7 0.3 0.2 0.4 0.1 0.8 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.2 0.1 0.0 0.3 0.5 2.0 0.6 0.2 0.1 0.5 0.3 0.5 0.1 0.6 0.8 0.0 0.0 0.0 0.3 0.0 73.7 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.9 0.0 0.0 1.3 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 15.5 0.9 0.0 0.2 1718.2 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.3 14.5 0.0 0.5 0.1 0.0 0.0 MPP1 "DXS552E, PEMP" ENSG00000130830 "Membrane palmitoylated protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 116.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.9;Erythroid cells: 393.8;Hofbauer cells: 291.9;Macrophages: 155.9;Syncytiotrophoblasts: 454.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 215.7;neutrophil: 202.1" "Group enriched" "Detected in all" 8 "dendritic cells: 57.7;granulocytes: 215.7;monocytes: 98.8" "Cell line enhanced" "Detected in many" "HEL: 218.0;REH: 136.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 650000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (2.15e-1)" "unprognostic (4.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.83e-3)" "unprognostic (7.14e-2)" "unprognostic (2.60e-2)" "unprognostic (7.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (7.79e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-3)" "prognostic favorable (4.60e-6)" "unprognostic (6.69e-2)" "unprognostic (2.53e-2)" "unprognostic (4.68e-2)" "unprognostic (6.67e-3)" 24.1 27.2 21.0 27.1 22.0 116.8 16.5 26.2 29.7 11.6 18.6 17.2 59.4 13.4 5.3 10.5 15.7 24.3 26.0 22.5 25.2 42.9 37.5 28.3 24.9 28.3 21.9 10.6 34.6 30.7 9.7 86.5 30.7 15.5 17.6 10.6 23.7 18.1 29.2 10.2 47.3 19.7 22.5 40.9 11.8 7.1 27.3 72.8 14.0 27.2 12.5 21.3 10.0 28.2 41.4 8.3 18.7 18.7 19.0 20.1 59.5 15.3 23.3 25.3 30.8 23.7 3.7 32.8 29.3 17.1 67.9 4.6 21.6 6.9 19.9 34.9 38.0 218.0 5.7 25.3 28.6 44.4 121.4 19.4 9.0 28.2 7.0 25.9 58.5 42.1 96.1 5.3 28.7 0.2 102.6 60.3 1.9 3.8 28.2 136.0 4.8 15.5 14.8 3.3 4.7 7.5 12.7 1.2 13.3 18.5 3.2 25.8 26.6 23.2 12.5 51.8 41.7 36.6 52.9 12.5 32.7 61.7 11.1 49.7 95.6 215.7 5.1 76.6 6.0 7.8 5.9 5.7 57.7 2.7 15.4 7.9 202.1 10.1 98.8 15.5 3.5 79.1 21.0 22.0 26.2 29.7 22.5 25.2 28.3 21.9 30.7 22.5 27.3 28.2 18.3 3.2 11.2 8.1 6.3 8.7 4.8 0.2 8.0 10.2 7.1 5.1 17.0 41.5 6.2 7.3 4.2 410.9 6.9 16.3 21.5 11.7 0.6 3.5 5.7 18.9 11.5 393.8 16.1 2.8 27.0 11.4 1.1 6.4 90.6 9.6 11.7 10.6 291.9 16.8 17.1 4.4 0.0 104.7 30.2 2.4 8.7 155.9 10.6 15.9 52.5 15.4 9.2 6.0 5.9 3.7 4.1 13.2 8.1 3.1 57.4 66.3 2.2 8.2 0.0 8.6 10.3 0.7 6.8 6.4 6.0 454.4 9.9 14.5 5.8 1.2 MPP5 "FLJ12615, PALS1" ENSG00000072415 "Membrane palmitoylated protein 5" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA000993: AB_1079407, HPA063890: AB_2732707" "unprognostic (3.65e-1)" "unprognostic (3.82e-3)" "unprognostic (4.56e-2)" "unprognostic (9.20e-2)" "unprognostic (9.86e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-3)" "unprognostic (9.89e-3)" "prognostic favorable (1.71e-12)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (6.90e-2)" "unprognostic (6.87e-2)" 7.4 8.7 13.9 6.3 20.9 5.6 10.6 17.6 16.5 8.8 26.6 12.7 20.4 6.3 21.1 13.6 7.3 7.9 7.4 11.9 17.4 31.4 19.6 12.3 4.8 18.2 18.2 6.1 8.7 19.6 7.2 9.8 18.3 16.2 12.0 17.2 18.4 12.7 18.0 8.4 20.7 7.2 18.1 6.6 9.4 8.8 17.5 10.3 25.1 13.6 6.1 9.0 8.4 27.5 156.4 24.4 24.1 18.5 13.3 12.3 20.6 46.4 23.6 33.2 21.6 23.8 45.9 12.7 21.5 37.8 11.0 31.0 13.9 26.1 50.2 5.5 9.5 11.8 23.6 16.8 15.5 4.5 8.5 13.1 10.0 17.9 23.7 24.2 19.0 13.5 12.6 4.7 53.9 20.4 14.4 5.0 7.7 22.2 16.2 12.2 37.1 15.2 30.1 36.8 13.2 9.4 28.2 27.0 15.5 21.1 28.6 9.2 29.2 41.4 87.2 13.8 19.9 7.8 7.6 19.3 27.2 10.1 14.7 0.1 0.5 0.8 0.4 1.0 0.3 1.1 0.5 0.6 0.8 0.4 1.1 0.6 0.0 2.2 0.7 0.6 0.3 0.4 13.9 20.9 17.6 16.5 11.9 17.4 18.2 18.2 18.3 18.1 17.5 27.5 13.2 64.1 28.9 37.2 8.8 21.0 26.0 14.6 22.2 8.5 22.4 12.8 24.7 11.5 21.1 22.0 43.8 23.1 5.2 47.2 13.7 21.7 5.9 29.5 15.0 17.7 5.4 6.7 24.8 26.9 11.3 17.3 18.3 46.2 5.1 15.8 17.2 20.7 17.6 3.3 34.7 21.2 12.2 11.9 13.4 4.5 8.1 9.2 3.6 22.5 6.6 23.4 3.1 41.2 129.8 26.7 32.5 11.3 13.1 30.1 54.3 33.5 14.9 34.3 6.6 17.7 22.2 22.4 36.1 29.2 17.3 17.5 7.7 7.5 22.4 38.7 MSI1 ENSG00000135097 "Musashi RNA binding protein 1" O43347 12 120341330-120369164 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 104.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Early spermatids: 55.4;Late spermatids: 58.2;Muller glia cells: 82.4;Rod photoreceptor cells: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 119.7;HAP1: 55.3;NTERA-2: 62.6;SCLC-21H: 88.4;SH-SY5Y: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074923, HPA075573" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074923: , HPA075573: " "unprognostic (1.21e-1)" "unprognostic (3.46e-3)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (3.89e-1)" "unprognostic (3.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.75e-2)" "prognostic favorable (5.99e-4)" "unprognostic (3.66e-1)" "unprognostic (1.46e-3)" "unprognostic (7.61e-2)" "unprognostic (7.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" 0.5 5.1 11.3 0.3 10.6 0.1 0.8 8.8 11.6 3.2 18.2 1.5 6.1 3.5 1.1 0.9 2.6 0.9 3.3 11.6 10.7 1.0 0.6 0.5 0.3 13.0 13.3 1.8 5.0 1.5 13.7 0.9 9.9 4.0 1.0 104.3 0.7 1.7 22.5 0.7 4.1 1.4 11.0 0.3 4.3 16.2 11.9 0.0 0.8 0.1 0.0 0.5 1.1 8.4 0.1 1.4 119.7 30.5 0.0 0.0 15.2 0.1 0.0 0.8 1.3 21.7 0.6 0.1 1.7 0.0 0.7 0.4 55.3 0.0 0.4 0.6 12.6 0.1 0.5 2.6 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.0 16.2 0.2 0.3 62.6 0.6 0.7 0.3 0.0 0.5 0.0 0.1 88.4 42.9 0.1 1.0 1.0 11.4 18.5 0.1 0.1 0.5 15.9 0.2 0.1 1.6 0.5 0.2 0.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 10.6 8.8 11.6 11.6 10.7 13.0 13.3 9.9 11.0 11.9 8.4 0.1 0.0 0.0 23.8 0.0 1.0 1.4 0.0 1.8 18.4 4.8 2.8 3.3 0.0 0.0 0.0 54.2 0.2 0.0 1.1 1.9 1.2 55.4 3.8 2.1 1.3 10.1 0.0 1.1 5.2 0.6 2.0 0.0 3.5 0.0 1.2 0.0 0.0 0.1 3.3 2.5 3.5 0.0 0.0 0.4 58.2 0.3 0.1 0.0 1.9 0.6 82.4 0.0 9.5 0.5 1.2 12.0 0.4 0.0 8.3 1.2 0.0 0.0 109.9 13.1 4.6 3.2 7.6 3.1 0.1 0.0 0.4 0.1 0.1 8.6 0.6 MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969651-92985066 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.1;placenta: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "GAMG: 4.9;SuSa: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074024 Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA074024: " "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" 0.0 0.0 2.2 0.0 2.8 0.0 0.0 0.7 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 3.0 2.8 0.0 0.0 0.0 0.0 1.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 0.7 1.1 2.3 1.2 3.0 2.8 3.1 2.1 1.2 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 NPVF "C7orf9, RFRP" ENSG00000105954 "Neuropeptide VF precursor" Q9HCQ7 7 25224570-25228486 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "retina: 220.5" "Cell type enriched" "Detected in some" 40 "Muller glia cells: 526.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "hypothalamus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "hypothalamus: 6.1" "Region enriched" "Detected in single" 8 "hypothalamus: 3.0" HPA041733 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 5: Muller glia cells - Visual perception" "HPA041733: AB_10794524" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 526.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NRL "D14S46E, NRL-MAF, RP27" ENSG00000129535 "Neural retina leucine zipper" P54845 14 24078662-24115010 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 75 "retina: 317.3" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 3720.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 4.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB026066, HPA064599" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 79: Retina - Phototransduction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "CAB026066: , HPA064599: AB_2685295" "unprognostic (2.71e-2)" "unprognostic (8.17e-4)" "unprognostic (4.60e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (1.99e-2)" "unprognostic (5.29e-2)" "unprognostic (1.88e-5)" "unprognostic (3.59e-2)" "unprognostic (7.84e-3)" "unprognostic (1.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.38e-5)" "unprognostic (2.56e-2)" "unprognostic (1.10e-1)" "unprognostic (1.73e-1)" "unprognostic (1.35e-3)" 0.8 2.5 1.7 0.5 1.5 0.5 1.0 2.3 2.2 1.1 0.6 0.9 1.1 1.1 0.7 1.1 1.0 0.9 2.2 1.5 1.5 3.1 3.6 1.0 1.0 2.3 1.8 1.2 1.7 1.9 2.4 0.3 1.7 1.5 0.3 317.3 1.0 0.7 2.5 0.7 1.3 0.3 1.7 2.1 1.2 4.2 1.6 1.2 2.7 1.4 0.7 1.1 0.8 1.7 0.3 1.2 1.6 1.6 0.3 0.2 0.4 0.3 0.3 0.5 0.3 0.7 0.5 1.2 0.4 0.5 1.0 0.5 0.6 0.3 0.2 0.6 0.5 0.7 0.6 2.2 0.6 1.4 1.6 0.4 0.5 0.2 0.7 0.7 0.5 2.2 0.7 1.2 0.3 0.9 1.2 0.6 1.8 1.8 0.9 1.2 1.5 0.0 0.4 1.3 1.7 1.2 0.8 0.7 0.8 4.8 0.9 1.5 0.4 1.1 0.5 0.1 0.7 3.6 1.9 1.5 0.3 0.9 1.1 0.2 0.3 1.3 0.2 0.4 0.1 1.0 0.2 0.4 0.3 0.7 0.8 0.6 0.1 0.5 0.3 0.4 0.2 0.3 1.7 1.5 2.3 2.2 1.5 1.5 2.3 1.8 1.7 1.7 1.6 1.7 1.4 0.0 0.5 5.5 6.2 0.8 1.6 0.1 1.2 434.4 2.0 1.9 2.1 0.0 0.7 7.3 431.6 1.4 3.2 1.5 13.7 0.6 2.7 1.3 0.7 24.1 1.8 3.2 1.8 1.1 0.9 0.7 2.6 1.0 0.0 0.7 0.7 3.3 2.0 250.7 2.6 1.7 0.0 1.3 0.4 4.2 1.2 1.4 1.8 0.0 1.1 636.4 5.2 2.0 4.4 0.3 5.3 1.9 1.7 2.0 5.6 6.7 0.1 3720.7 0.0 1.2 0.7 9.7 4.3 2.2 0.4 2.5 2.6 2.3 1.0 2.1 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654547-86666848 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9;skeletal muscle: 2.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 4.6;Excitatory neurons: 2.8;Inhibitory neurons: 1.9;Smooth muscle cells: 2.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039147: AB_10673304" "unprognostic (3.67e-3)" "unprognostic (1.40e-2)" "unprognostic (3.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.03e-3)" "unprognostic (2.89e-2)" "unprognostic (3.26e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (8.88e-3)" "unprognostic (1.93e-6)" "unprognostic (4.10e-2)" "unprognostic (5.58e-2)" "unprognostic (6.76e-2)" 2.0 0.1 1.5 0.0 7.9 0.0 0.7 0.0 3.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.2 0.0 0.1 1.1 0.6 0.0 2.5 0.7 0.4 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.8 0.4 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.9 0.0 3.0 1.6 0.0 0.1 0.1 0.2 0.1 1.4 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.6" "Group enriched" "Detected in some" 11 "Early spermatids: 27.1;Late spermatids: 25.6;Spermatocytes: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA026084: AB_2671807" "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 13.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 61.6;retina: 68.9" "Group enriched" "Detected in some" 4 "Horizontal cells: 264.2;Muller glia cells: 462.6" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;AN3-CA: 20.1;HEK 293: 18.0;HeLa: 14.9;hTERT-RPE1: 50.6;U-251 MG: 16.5" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB034143: AB_1127044, HPA030775: AB_10601243" "unprognostic (2.89e-1)" "unprognostic (2.98e-2)" "unprognostic (8.34e-2)" "unprognostic (3.85e-2)" "unprognostic (4.42e-2)" "unprognostic (7.82e-2)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.24e-3)" "unprognostic (1.68e-1)" "unprognostic (1.20e-2)" "unprognostic (3.91e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (3.42e-3)" 0.0 0.6 21.7 0.0 22.9 0.2 0.1 61.6 34.1 0.0 16.5 0.2 1.7 0.0 0.6 0.0 0.0 0.0 0.0 23.6 20.7 0.8 0.1 0.0 0.0 22.0 18.1 0.0 9.2 0.0 4.3 0.0 21.7 0.0 0.3 68.9 0.1 0.0 0.8 0.5 0.9 0.0 21.4 0.0 9.4 1.6 19.6 0.4 0.0 0.0 0.1 0.1 0.1 25.8 0.0 0.2 15.1 20.1 4.6 6.6 5.9 0.0 0.0 0.2 0.0 1.3 3.7 0.1 6.3 2.3 9.0 0.4 1.8 0.0 0.3 0.0 18.0 8.9 14.9 8.4 0.0 0.5 0.0 0.1 0.7 0.1 0.5 50.6 0.0 5.2 7.6 0.0 0.2 0.0 3.7 0.6 0.3 0.0 10.1 0.0 7.3 0.1 0.8 0.6 0.7 0.0 0.4 0.1 0.0 0.0 4.7 0.0 0.0 5.3 0.4 0.0 16.5 0.1 0.2 0.1 8.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.7 22.9 61.6 34.1 23.6 20.7 22.0 18.1 21.7 21.4 19.6 25.8 0.2 0.0 0.0 76.7 0.1 0.5 0.0 0.0 0.0 78.8 0.5 0.0 3.8 0.0 0.0 0.0 12.5 0.1 0.1 0.2 0.0 0.0 0.7 0.2 0.5 1.0 74.6 0.0 3.6 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 264.2 1.6 3.1 0.0 0.0 0.4 0.6 0.0 0.2 0.0 3.7 0.6 462.6 0.0 3.5 0.6 2.5 1.3 0.0 0.0 0.0 0.1 0.2 0.0 30.6 0.0 0.9 0.5 21.4 7.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 PDC MEKA ENSG00000116703 Phosducin P20941 1 186443566-186461114 "Predicted intracellular proteins" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 478 "retina: 668.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 99.1;Cone photoreceptor cells: 362.8;Muller glia cells: 179.8;Rod photoreceptor cells: 999.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 1.3;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.0" "Low region specificity" "Detected in all" HPA062235 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA062235: AB_2684720" "unprognostic (2.06e-2)" "unprognostic (3.31e-1)" "unprognostic (1.89e-1)" "unprognostic (5.90e-4)" "unprognostic (2.18e-1)" "unprognostic (7.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (2.39e-2)" "unprognostic (8.28e-3)" "unprognostic (4.07e-7)" "unprognostic (3.48e-2)" "unprognostic (2.11e-2)" "unprognostic (1.61e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 668.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 99.1 0.0 0.0 0.1 0.0 0.0 0.0 362.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 6.2 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 57.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 179.8 0.0 2.5 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 999.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857953-149944793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "retina: 1119.5" "Cell type enriched" "Detected in many" 11 "Rod photoreceptor cells: 2946.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "CACO-2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.1 0.7 0.5 0.2 0.5 0.9 0.2 1.4 0.7 0.1 0.2 1.2 0.2 0.1 16.3 0.9 0.2 0.2 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.3 0.3 0.2 0.2 0.2 1.7 0.1 0.5 0.3 0.9 1119.5 0.4 0.2 0.3 0.6 0.1 0.1 0.2 0.2 0.2 1.5 0.6 0.0 0.4 0.0 0.2 0.0 0.1 1.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 2.5 0.2 0.3 0.4 0.0 0.4 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.2 0.2 0.0 0.0 0.1 0.4 0.4 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.5 0.5 1.4 0.7 0.5 0.5 0.3 0.3 0.5 0.2 0.6 1.2 0.9 0.0 5.8 0.0 0.4 1.1 0.6 0.8 0.0 150.5 0.5 0.4 6.7 0.0 2.8 0.0 244.0 1.1 1.6 14.3 0.0 0.1 18.4 1.5 0.5 11.6 0.0 0.0 1.2 0.2 2.2 1.2 0.0 2.5 3.8 1.9 2.2 0.6 0.3 75.7 0.6 0.4 2.0 1.9 0.4 5.5 1.2 1.5 0.0 0.0 1.4 263.1 5.2 0.5 0.2 0.1 2.8 0.4 0.3 0.4 0.4 0.1 3.2 2946.4 0.0 1.0 1.2 2.3 0.8 5.4 0.6 2.9 1.5 2.2 2.7 0.2 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625573-670782 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 385.0" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 460.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 11.5;JURKAT: 17.3;MOLT-4: 31.3;REH: 16.8;SCLC-21H: 20.2;SH-SY5Y: 11.9;U-266/84: 24.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA054148: AB_2682401, HPA059929: AB_2684166" "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favorable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.9 2.2 13.5 5.5 25.7 8.4 4.1 8.2 22.3 2.5 1.9 1.7 1.2 2.7 4.0 1.7 10.2 3.7 5.9 11.2 22.6 4.9 1.0 4.6 14.3 22.8 19.9 2.8 1.8 8.2 4.1 3.1 25.5 2.8 1.3 385.0 3.8 3.0 1.1 2.1 3.0 2.5 9.3 10.1 2.9 4.4 24.1 12.2 12.0 0.1 9.3 3.8 1.4 39.3 0.1 0.0 1.2 0.5 0.3 0.4 0.4 0.0 0.1 0.8 2.0 0.0 0.1 0.3 11.5 0.3 0.9 0.1 2.5 0.6 0.0 0.1 0.0 1.0 0.3 0.1 5.8 0.2 0.4 0.7 0.0 3.5 0.0 0.8 1.1 17.3 0.1 1.0 0.1 0.3 31.3 0.1 9.4 0.7 0.0 16.8 0.2 0.2 2.1 1.3 20.2 11.9 0.0 0.3 0.1 4.2 0.6 0.0 0.4 0.2 1.2 0.2 0.4 7.7 24.0 0.3 0.3 0.3 0.2 16.8 5.4 0.9 14.0 7.7 12.6 12.8 9.3 9.8 8.5 21.4 14.6 15.8 1.4 14.4 8.1 18.2 15.5 9.4 13.5 25.7 8.2 22.3 11.2 22.6 22.8 19.9 25.5 9.3 24.1 39.3 0.5 3.2 5.0 4.2 6.4 0.4 2.1 1.2 2.8 20.7 3.9 2.4 4.4 0.0 3.5 0.0 83.4 0.1 8.4 0.2 1.9 6.9 0.4 7.0 2.2 2.9 1.8 7.4 40.3 0.6 0.3 1.3 1.5 2.5 3.8 5.4 2.2 0.0 11.3 11.8 27.3 0.5 4.1 5.1 1.4 0.3 1.5 3.3 3.6 4.7 6.2 31.1 7.2 10.1 33.9 0.8 0.2 1.5 7.5 1.9 0.0 8.4 11.2 460.1 0.0 1.6 1.1 4.3 11.0 1.9 0.3 0.3 5.9 3.5 0.4 1.3 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 99 "retina: 2050.3" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 4448.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basophil: 127.0;NK-cell: 220.2" "Group enriched" "Detected in all" 6 "granulocytes: 127.0;NK-cells: 220.2" "Cell line enhanced" "Detected in some" "Hep G2: 5.2;NB-4: 5.8;NTERA-2: 8.9;REH: 11.9;SuSa: 6.2" "Region enhanced" "Detected in some" "hippocampal formation: 4.7" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 1.5 0.3 0.0 4.7 0.1 7.8 0.9 0.2 0.5 1.0 0.2 1.6 0.6 0.2 0.1 0.8 0.7 2.5 0.4 0.1 0.7 2.1 4.2 3.0 20.6 0.1 0.2 0.0 0.0 0.1 0.1 12.0 0.2 0.2 1.0 2050.3 0.5 0.4 1.2 0.3 1.6 0.9 0.1 19.9 1.7 0.8 0.3 8.3 0.4 0.3 7.1 3.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.3 0.1 0.2 0.0 0.9 0.0 0.0 0.0 0.0 5.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.8 0.2 0.1 0.2 0.4 0.3 0.0 5.8 8.9 0.0 0.0 11.9 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.1 0.1 6.2 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.1 0.6 0.9 0.4 3.1 0.1 127.0 18.1 30.5 4.1 26.2 1.3 2.7 0.8 2.3 28.9 5.1 2.1 7.4 2.4 220.2 15.5 2.9 0.1 13.5 0.0 0.1 0.2 0.5 0.1 0.7 0.1 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.6 0.3 1.1 0.9 0.0 0.0 0.6 422.5 0.3 0.4 0.2 0.0 0.0 5.5 517.1 0.2 4.3 0.1 1.9 0.4 0.8 1.5 0.3 27.2 0.0 1.7 0.2 0.2 0.4 0.2 0.0 0.5 23.6 0.1 2.9 0.2 22.6 262.5 0.1 0.2 0.0 4.8 8.0 2.3 0.0 4.4 3.6 0.0 13.3 709.0 11.3 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.1 1.0 0.0 4448.6 0.0 0.1 0.1 1.1 0.2 0.3 1.4 0.3 1.7 2.1 0.0 0.1 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973042-14981865 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "retina: 911.3" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 831.9;Rod photoreceptor cells: 218.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.0" "Low region specificity" "Detected in single" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 79: Retina - Phototransduction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.0 0.4 0.3 0.0 0.4 4.0 0.0 0.1 1.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 911.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 1.0 0.3 2.3 0.3 0.4 0.5 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.9 0.0 0.0 0.1 0.0 0.0 0.0 831.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.5 0.0 21.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 23.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.6 81.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 132.7;ovary: 47.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 75.3;Cone photoreceptor cells: 70.9;Leydig cells: 81.4;Peritubular cells: 73.4;Sertoli cells: 263.0;Smooth muscle cells: 63.1" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053361 Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 8.9 1.5 8.7 1.4 10.9 0.0 3.4 10.5 14.4 1.2 22.1 33.7 0.7 1.8 0.9 4.4 6.4 2.0 132.7 9.1 9.7 0.1 6.1 8.0 0.6 10.2 10.9 47.6 0.9 0.0 0.8 4.7 9.2 14.9 2.3 18.9 2.7 7.7 0.5 1.7 3.0 3.3 9.5 1.6 6.3 10.1 11.8 0.0 2.4 0.3 1.2 17.6 1.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 10.9 10.5 14.4 9.1 9.7 10.2 10.9 9.2 9.5 11.8 8.6 0.7 0.0 0.5 25.8 0.0 0.4 0.0 0.0 0.0 11.6 0.2 1.3 75.3 0.0 0.0 0.0 70.9 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.1 0.0 0.0 0.2 0.0 0.1 30.8 0.0 0.0 0.0 6.7 10.8 0.1 0.3 0.0 0.2 0.0 0.0 1.2 0.7 4.9 81.4 0.5 0.0 1.9 0.0 30.8 0.0 0.5 0.1 0.0 0.0 73.4 0.0 1.3 0.0 0.0 0.0 32.1 263.0 0.5 63.1 0.6 0.7 0.0 0.4 0.3 0.1 0.0 0.0 0.1 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.6;salivary gland: 57.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.9;Horizontal cells: 164.9;Inhibitory neurons: 113.8;Microglial cells: 183.6;Oligodendrocyte precursor cells: 168.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Region enhanced" "Detected in all" "cerebellum: 55.6" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 18 "dendritic cells: 3.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 91.4;hTERT-HME1: 45.9;LHCN-M2: 77.6;OE19: 48.2;RPTEC TERT1: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoplasm "HPA007951: AB_2667944" "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 6.3 7.2 8.6 3.4 3.7 0.5 7.0 55.6 6.3 4.6 31.0 20.5 2.6 8.2 24.4 9.0 15.0 5.9 17.9 2.5 10.8 3.0 0.3 5.4 1.7 13.4 17.8 2.1 2.1 0.7 8.2 6.5 12.0 9.7 17.9 15.1 57.4 6.1 2.7 4.6 4.2 9.1 5.3 1.3 14.4 2.4 23.3 4.5 32.7 6.8 2.3 8.2 5.3 6.5 0.0 15.1 7.9 0.0 0.0 0.4 0.1 35.8 9.5 10.9 6.1 3.4 2.6 0.0 0.6 91.4 39.0 0.1 2.3 7.6 14.7 0.0 5.3 3.8 5.7 0.0 1.6 0.0 0.0 2.3 3.0 12.7 45.9 18.7 0.1 0.0 4.3 0.4 77.6 5.0 0.0 0.0 8.8 48.2 10.4 0.0 0.0 0.7 96.9 5.8 25.5 18.4 0.0 23.8 15.1 10.5 19.2 0.2 0.5 11.2 0.9 1.2 14.2 0.0 0.0 0.0 1.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 8.6 3.7 55.6 6.3 2.5 10.8 13.4 17.8 12.0 5.3 23.3 6.5 37.8 6.4 0.5 60.1 0.3 2.4 3.8 1.5 2.2 82.9 5.7 5.3 72.6 0.0 8.9 5.5 0.0 0.0 4.5 17.9 0.0 0.7 1.4 46.2 4.6 40.4 42.0 0.0 105.9 0.2 0.0 9.0 18.8 53.5 0.0 36.6 1.8 0.0 0.1 164.9 113.8 36.4 14.2 0.0 2.1 1.2 1.5 0.8 7.2 183.6 0.6 2.9 0.0 168.9 2.9 7.1 9.7 20.7 0.2 8.5 2.1 1.2 39.5 6.6 13.1 10.5 36.0 1.5 2.0 0.5 1.0 0.1 1.4 4.8 40.4 2.5 POU4F1 "BRN3A, RDC-1" ENSG00000152192 "POU class 4 homeobox 1" Q01851 13 78598362-78603552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.3;retina: 2.6" "Cell type enriched" "Detected in some" 10 "Skeletal myocytes: 28.6" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 4 "medulla oblongata: 9.3;midbrain: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.1;HEL: 15.5;JURKAT: 12.2;REH: 10.9;RH-30: 17.9;SCLC-21H: 17.1;U-266/70: 16.1" "Group enriched" "Detected in some" 23 "midbrain: 2.5;pons and medulla: 2.1;thalamus: 2.2" "Region enhanced" "Detected in some" "medulla oblongata: 4.1" HPA068024 Enhanced Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA068024: AB_2685943" "unprognostic (6.70e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (6.30e-2)" "unprognostic (6.00e-2)" "unprognostic (1.70e-2)" "unprognostic (9.17e-2)" "unprognostic (8.98e-2)" "unprognostic (9.95e-2)" "unprognostic (1.53e-1)" "unprognostic (4.75e-3)" 0.0 0.0 0.4 0.1 0.3 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.5 9.3 5.2 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.0 1.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.7 2.7 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.6 0.0 5.1 0.0 0.0 0.0 14.1 15.5 0.0 2.0 0.0 7.7 4.4 0.0 0.1 0.0 0.0 0.0 0.0 12.2 3.1 0.0 0.7 0.0 1.2 1.4 0.0 2.1 0.0 10.9 17.9 0.0 0.0 0.0 17.1 0.2 0.0 0.0 0.7 0.2 0.0 1.5 0.2 0.0 0.0 0.3 0.0 16.1 5.1 0.0 0.0 8.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.2 0.4 0.6 9.3 5.2 1.6 1.7 0.8 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.1 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 2.0 0.0 28.6 0.1 2.5 2.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "retina: 641.4" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 260.6;Rod photoreceptor cells: 482.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.0;ASC TERT1: 3.4;fHDF/TERT166: 5.3;HHSteC: 7.8;HSkMC: 6.0;LHCN-M2: 3.5" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" 1.1 0.8 2.1 0.5 1.5 0.0 0.5 0.4 1.8 2.0 0.1 2.2 0.4 2.1 1.8 0.7 1.3 1.1 1.5 3.1 2.1 1.4 0.2 1.5 0.1 0.9 1.0 3.1 2.3 4.3 2.5 0.9 1.2 1.5 0.8 641.4 0.7 1.1 13.2 0.3 1.4 1.9 0.4 0.8 1.2 3.7 2.7 0.2 4.1 2.9 0.1 1.2 1.1 1.2 0.0 0.0 0.0 0.0 3.0 3.4 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 7.8 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.2 0.0 0.1 0.0 2.1 1.5 0.4 1.8 3.1 2.1 0.9 1.0 1.2 0.4 2.7 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 39.3 0.1 0.0 0.9 0.0 0.1 0.0 260.6 0.1 0.0 0.0 3.9 0.3 0.2 0.1 0.9 2.3 0.0 0.0 2.3 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.4 0.2 0.0 11.8 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.9 0.0 42.6 1.0 0.5 0.6 0.5 0.0 1.9 0.0 0.2 0.0 0.2 0.0 482.7 0.0 0.9 0.8 2.3 0.5 0.1 0.3 0.1 0.0 1.3 0.0 0.1 RARB "HAP, NR1B2, RRB2" ENSG00000077092 "Retinoic acid receptor beta" P10826 3 25174332-25597932 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Microphthalmia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 41.4;Excitatory neurons: 66.8;Inhibitory neurons: 92.6;Microglial cells: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 13.7;HEK 293: 16.0;hTERT-RPE1: 82.3;WM-115: 36.5" "Region enriched" "Detected in all" 9 "basal ganglia: 109.2" "CAB002617, HPA004174" Enhanced Enhanced Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB002617: , HPA004174: AB_1079744" "unprognostic (2.04e-2)" "unprognostic (3.53e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.43e-1)" "unprognostic (4.71e-2)" "unprognostic (1.62e-1)" "unprognostic (2.86e-1)" "prognostic favorable (3.43e-5)" "unprognostic (9.24e-3)" "unprognostic (2.28e-1)" "unprognostic (9.99e-2)" "unprognostic (6.56e-3)" 4.1 7.0 3.5 2.6 15.0 0.0 6.9 2.2 6.6 9.3 7.2 6.0 1.7 7.4 6.7 7.9 6.0 5.3 14.0 3.5 1.4 15.1 6.5 5.3 6.7 3.4 1.7 11.5 1.3 6.0 7.5 14.4 0.9 12.5 2.2 13.6 13.1 11.2 2.4 1.1 2.0 5.9 1.4 4.9 3.9 0.6 2.4 1.2 9.1 5.3 4.2 7.2 6.1 3.7 0.0 1.9 1.2 6.4 13.7 3.6 0.0 1.6 0.8 0.0 0.6 0.3 0.1 0.1 0.2 2.5 0.3 0.4 0.0 0.3 0.0 0.1 16.0 0.1 0.1 1.1 0.3 0.2 0.1 7.1 0.0 0.0 0.0 82.3 13.4 0.1 0.1 5.6 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.6 8.3 0.0 0.2 0.1 9.1 0.0 0.1 0.0 1.1 0.1 2.1 7.0 0.2 0.0 0.1 5.6 0.2 36.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 15.0 2.2 6.6 3.5 1.4 3.4 1.7 0.9 1.4 2.4 3.7 2.4 0.0 0.5 41.4 0.3 0.1 18.0 6.4 1.8 4.5 1.7 7.5 12.0 12.8 14.9 11.0 25.0 0.2 0.8 0.0 0.0 1.6 1.5 8.3 4.2 10.5 0.0 0.0 66.8 0.9 0.1 6.8 7.7 3.0 0.0 0.1 22.1 2.1 0.4 5.0 92.6 0.0 2.0 1.9 0.4 1.2 0.0 0.3 0.0 29.0 0.0 24.8 0.0 19.6 2.9 1.4 0.0 0.0 0.2 10.2 0.6 0.6 9.2 6.3 0.0 2.9 9.7 0.2 1.0 6.6 0.1 0.3 0.5 0.2 0.2 9.7 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 20.7 18.7 8.9 22.8 9.7 19.3 17.8 12.0 13.0 18.8 10.9 15.1 14.6 15.7 21.2 21.9 13.1 17.3 17.8 8.5 10.9 18.4 14.5 18.1 30.7 13.9 10.3 11.5 9.2 20.5 6.5 24.9 13.4 15.1 17.1 12.5 16.9 15.9 19.0 23.6 15.6 18.3 11.6 24.8 16.3 12.9 9.3 34.2 22.4 21.2 30.1 19.8 10.6 15.1 29.1 15.8 40.9 44.2 19.8 22.8 18.5 56.6 45.9 57.4 48.3 13.4 49.8 37.3 12.8 37.4 31.7 39.6 53.7 44.8 86.6 53.0 20.8 68.5 29.4 22.7 21.1 59.5 62.0 12.9 27.0 37.3 47.1 47.8 40.1 90.1 23.4 29.6 66.4 13.7 187.2 29.8 20.0 65.6 17.3 79.8 41.1 43.0 59.6 27.6 2.0 41.8 55.1 27.3 46.2 36.2 29.8 76.3 32.1 35.3 23.3 43.7 51.2 13.1 3.9 0.4 18.8 36.7 48.9 23.8 14.9 8.8 6.9 19.9 5.6 30.2 5.7 6.9 15.2 29.4 4.8 5.6 20.6 5.9 20.9 16.9 7.4 7.1 8.9 9.7 12.0 13.0 8.5 10.9 13.9 10.3 13.4 11.6 9.3 15.1 59.2 3.2 19.6 75.4 97.3 28.4 23.3 27.6 63.2 17.3 26.9 21.0 18.3 14.3 19.2 31.3 29.2 7.1 50.1 17.8 15.6 19.3 28.1 40.1 36.2 46.4 17.5 50.7 99.5 11.9 9.6 22.2 29.0 40.4 12.0 25.9 35.7 17.3 77.4 18.5 98.9 20.0 8.2 105.3 198.9 13.9 26.1 104.2 26.6 152.7 93.7 20.4 22.6 101.0 98.3 17.4 10.7 28.6 69.9 24.0 15.7 23.6 25.3 19.6 19.7 28.5 32.3 33.0 21.3 72.1 38.2 4.4 38.3 21.2 16.6 18.0 RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 335 "retina: 542.3" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 2070.4;Rod photoreceptor cells: 1610.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 542.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.3 1.2 1.6 0.5 0.3 0.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.7 0.0 0.0 0.5 0.0 0.0 0.0 2070.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1610.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RCVRN RCV1 ENSG00000109047 Recoverin P35243 17 9896320-9905271 "Plasma proteins, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 434 "retina: 463.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1926.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "WM-115: 1.8" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA015783, CAB022363" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB022363: , HPA015783: AB_2669298" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" "unprognostic (7.95e-3)" "unprognostic (4.82e-2)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-4)" "unprognostic (1.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.41e-2)" "unprognostic (9.23e-2)" 0.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 1.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 463.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 230.5 0.0 0.0 0.5 0.0 0.0 0.0 475.4 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 11.5 0.0 0.0 1.5 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 107.7 0.7 0.0 0.0 0.0 0.9 0.7 2.5 0.5 1.8 0.0 0.1 393.9 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1926.6 0.0 1.7 0.3 0.1 0.5 0.0 0.3 0.1 0.1 0.0 0.0 0.0 RD3 "C1orf36, LCA12" ENSG00000198570 "Retinal degeneration 3, GUCY2D regulator" Q7Z3Z2 1 211476522-211492162 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "retina: 47.2" "Group enriched" "Detected in some" 10 "Bipolar cells: 82.7;Cone photoreceptor cells: 100.1;Rod photoreceptor cells: 66.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 4.6;HMC-1: 14.4;SH-SY5Y: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029941, HPA029943" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA029941: AB_2732449, HPA029943: AB_2732450" "unprognostic (1.42e-1)" "unprognostic (2.75e-2)" "unprognostic (1.14e-2)" "unprognostic (6.07e-2)" "unprognostic (2.96e-2)" "unprognostic (2.18e-1)" "unprognostic (9.54e-2)" "unprognostic (7.87e-2)" "unprognostic (1.15e-1)" "unprognostic (4.80e-2)" "unprognostic (4.58e-2)" "unprognostic (2.86e-2)" 0.0 0.7 0.1 0.0 0.2 0.2 0.0 0.5 0.3 0.2 0.8 0.0 0.1 0.1 0.7 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.7 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.7 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.5 0.0 0.0 0.0 100.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RGS9 "MGC111763, MGC26458, PERRS, RGS9L" ENSG00000108370 "Regulator of G protein signaling 9" O75916 17 65100812-65227703 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.5" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 325.2;Rod photoreceptor cells: 480.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 9.7;MAIT T-cell: 2.5;memory CD8 T-cell: 6.8;naive CD8 T-cell: 3.2;NK-cell: 4.0" "Group enriched" "Detected in many" 42 "NK-cells: 4.0;T-cells: 9.7" "Cell line enhanced" "Detected in some" "HDLM-2: 25.9;HEL: 11.7;hTERT-RPE1: 4.7;SuSa: 4.1" "Region enriched" "Detected in all" 9 "basal ganglia: 248.1" "Region enriched" "Detected in all" 10 "basal ganglia: 110.0" "HPA013550, HPA014137" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "HPA013550: , HPA014137: AB_2668943" "unprognostic (4.43e-3)" "unprognostic (7.49e-3)" "unprognostic (5.12e-2)" "unprognostic (3.09e-5)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (4.88e-2)" "prognostic favorable (1.35e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-2)" "unprognostic (4.94e-2)" "unprognostic (3.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" 0.8 1.5 6.2 1.2 23.5 0.2 0.8 4.3 9.4 1.6 3.8 8.5 1.1 1.7 2.5 1.5 10.3 1.0 0.8 5.1 9.3 2.4 2.3 5.1 2.1 5.3 5.9 2.6 1.4 5.5 12.1 1.2 6.9 4.6 1.3 1.3 1.3 3.3 0.1 1.4 3.8 1.4 5.2 1.7 3.8 0.4 7.4 0.6 0.6 0.3 3.0 2.9 2.8 4.6 0.4 0.0 1.3 0.1 0.1 0.2 0.0 0.1 2.6 0.0 0.3 0.2 0.0 1.2 1.8 0.0 0.0 0.1 0.0 0.1 0.1 25.9 0.6 11.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.2 4.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.7 0.0 2.5 0.0 0.8 6.8 0.0 0.0 0.0 3.2 0.1 4.0 0.0 0.1 0.0 1.7 6.2 23.5 4.3 9.4 5.1 9.3 5.3 5.9 6.9 5.2 7.4 4.6 1.3 3.2 1.5 33.3 0.4 0.4 1.4 0.9 0.6 25.0 7.8 14.5 0.4 0.0 1.3 1.8 325.2 0.0 27.5 0.1 3.9 8.9 0.6 2.5 1.8 2.6 59.7 0.0 2.3 3.1 0.1 5.8 1.1 4.2 0.0 3.3 1.1 0.0 0.1 52.2 2.3 2.3 0.0 0.0 3.0 2.4 0.9 2.9 1.8 1.9 19.4 39.2 18.6 2.5 1.2 2.7 0.1 4.9 6.3 0.1 0.1 14.2 0.8 480.2 0.0 0.5 1.9 0.1 0.4 0.0 0.1 0.1 10.3 12.8 0.6 0.3 RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 28.9;retina: 17.4;skeletal muscle: 9.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 29.0;Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.3;HMC-1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" 0.0 0.1 0.8 0.0 0.7 0.0 0.0 0.8 0.8 0.0 28.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.3 3.3 0.9 0.3 0.0 0.3 0.0 1.1 1.4 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 17.4 0.1 0.1 9.0 0.1 0.0 0.0 0.5 0.0 0.1 0.4 1.5 0.1 0.0 3.2 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.1 6.3 0.1 0.0 0.1 0.1 1.6 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.8 0.1 0.2 0.0 1.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.3 0.0 0.2 0.3 0.1 0.1 0.3 0.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.8 0.8 3.3 0.9 1.1 1.4 0.9 0.5 1.5 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 29.0 0.4 0.4 4.6 0.0 0.0 1.8 56.3 0.3 0.6 0.5 0.0 0.0 5.1 0.2 0.1 0.7 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.8 0.7 0.0 0.2 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.4 0.9 0.0 75.4 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.1 1.1 0.4 0.0 RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528639-129535344 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5994 "retina: 4062.1" "Cell type enriched" "Detected in some" 7 "Rod photoreceptor cells: 4509.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: AB_2668844" "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-11)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4062.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 369.9 0.0 0.0 0.6 0.0 0.0 0.0 454.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 26.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 218.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 590.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4509.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "retina: 265.6" "Cell type enriched" "Detected in some" 34 "Muller glia cells: 3148.2" "Group enriched" "Detected in some" 30 "glioma: 3.7;melanoma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 53 "SK-MEL-30: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoplasm, Centrosome" "HPA042051: AB_2732495, HPA044083: AB_2678802" "unprognostic (3.19e-2)" "unprognostic (2.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (5.21e-2)" "unprognostic (3.17e-1)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (8.42e-2)" 0.0 0.2 14.9 0.1 16.9 0.1 0.0 15.0 20.8 0.0 16.7 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.0 15.7 14.5 0.0 0.0 0.0 0.0 14.5 14.2 0.0 0.0 0.0 2.6 0.0 14.3 0.0 0.1 265.6 0.0 0.0 0.1 0.0 0.4 0.1 14.0 0.0 0.2 0.9 14.9 0.0 0.0 0.1 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.9 16.9 15.0 20.8 15.7 14.5 14.5 14.2 14.3 14.0 14.9 14.9 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.3 0.0 0.0 0.0 39.6 4.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.0 3148.2 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 20.0 0.0 0.0 0.0 0.0 ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "retina: 1186.9" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 3239.7" "Cancer enriched" "Detected in all" 6 "glioma: 14.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Cell line enhanced" "Detected in many" "HSkMC: 25.2;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028910, HPA073279" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA028910: AB_2672824, HPA073279: " "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (4.05e-1)" "prognostic favorable (2.20e-4)" "unprognostic (2.20e-1)" "unprognostic (9.87e-2)" "unprognostic (7.65e-3)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.61e-1)" "unprognostic (4.65e-1)" "unprognostic (1.02e-1)" "unprognostic (7.24e-2)" 12.8 7.9 57.9 2.2 60.5 1.2 9.3 56.8 67.4 9.1 48.1 9.8 1.8 7.7 4.7 7.6 10.7 4.6 8.1 54.5 59.0 7.0 7.1 6.0 2.5 67.4 61.0 13.5 3.6 5.2 7.0 1.4 62.1 8.2 2.6 1186.9 4.2 5.0 3.3 5.4 5.3 5.4 60.0 7.5 7.0 6.2 63.1 1.6 6.0 3.7 2.5 9.6 7.3 62.1 3.2 1.9 3.1 6.6 4.5 22.0 0.6 2.1 3.7 4.3 2.8 0.9 5.3 3.0 15.9 12.2 2.0 4.1 1.5 4.2 1.1 5.3 3.0 3.1 8.6 4.0 13.0 1.1 0.9 25.2 5.9 4.5 9.1 15.1 7.0 1.2 4.0 6.5 9.1 8.3 1.7 2.3 0.8 1.7 5.9 1.6 2.6 19.1 5.0 1.8 3.3 5.1 5.0 5.8 2.5 0.5 8.1 1.4 8.3 7.2 2.7 8.3 2.5 2.9 31.9 2.4 14.2 3.1 1.5 0.0 0.4 0.3 0.3 0.1 0.9 0.2 1.2 0.3 0.2 0.3 0.5 0.6 0.1 2.7 0.4 0.3 0.4 0.5 57.9 60.5 56.8 67.4 54.5 59.0 67.4 61.0 62.1 60.0 63.1 62.1 19.9 0.0 4.4 4.9 0.6 3.7 5.7 5.0 7.4 356.6 3.8 7.2 2.5 2.8 2.3 5.5 594.2 1.0 0.6 2.4 1.9 1.6 2.0 1.0 4.1 31.3 4.2 0.0 0.2 3.1 0.2 4.1 1.1 1.0 1.3 1.2 21.8 1.7 1.1 171.6 0.5 2.8 0.0 1.9 0.8 7.9 19.0 1.2 3.6 1.9 1.3 516.9 1.0 1.0 6.5 2.1 2.5 5.7 0.6 3.1 3.1 4.7 2.7 3239.7 0.0 2.5 4.3 1.6 5.1 5.3 1.0 0.7 1.5 4.0 2.9 3.1 RP1 "DCDC4A, ORP1" ENSG00000104237 "RP1 axonemal microtubule associated" P56715 8 54509422-54871720 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "retina: 236.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 333.6;Rod photoreceptor cells: 1115.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.6;HDLM-2: 5.2;hTERT-RPE1: 2.0;RPTEC TERT1: 10.2;U-2197: 2.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.3" HPA042257 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA042257: AB_10797385" "unprognostic (3.19e-3)" "unprognostic (2.63e-3)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.70e-1)" "unprognostic (9.16e-3)" "unprognostic (6.24e-2)" "unprognostic (4.56e-2)" "unprognostic (4.13e-5)" "unprognostic (2.48e-1)" "unprognostic (2.16e-5)" "unprognostic (8.92e-2)" "unprognostic (6.18e-2)" "unprognostic (1.89e-2)" "unprognostic (8.96e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.7 0.1 3.5 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 236.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.6 0.0 0.1 0.0 0.7 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.1 0.5 16.0 4.8 0.0 0.0 0.0 0.0 1.2 0.0 72.5 3.0 1.4 0.4 0.0 31.1 5.5 333.6 0.0 0.0 0.0 3.9 0.0 0.3 81.9 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 32.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.5 1.8 0.0 0.0 130.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 149.0 1115.8 0.0 0.0 0.4 3.2 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 RP1L1 DCDC4B ENSG00000183638 "RP1 like 1" Q8IWN7 8 10606349-10712187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "retina: 44.1" "Group enriched" "Detected in some" 20 "Cone photoreceptor cells: 93.8;Rod photoreceptor cells: 68.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024686, HPA024744" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA024686: AB_2671650, HPA024744: AB_2671668" "unprognostic (3.27e-1)" "unprognostic (9.97e-2)" "unprognostic (1.24e-1)" "unprognostic (6.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-5)" "unprognostic (3.57e-1)" "unprognostic (5.22e-2)" "unprognostic (2.08e-4)" "unprognostic (8.52e-2)" "unprognostic (5.77e-2)" "unprognostic (6.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.82e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 44.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.6 0.8 0.1 0.0 4.0 0.2 0.3 0.8 0.0 0.0 0.0 93.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 3.3 0.0 0.5 0.6 0.1 0.0 0.4 0.0 0.7 0.0 0.1 0.0 68.0 0.0 1.6 0.5 0.0 0.5 0.0 0.9 0.0 0.1 0.1 0.0 1.0 RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 146.1;Hepatic stellate cells: 121.7;Respiratory ciliated cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.6" "Cell line enhanced" "Detected in many" "HL-60: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" 19.2 5.7 4.7 4.4 4.6 12.2 16.8 5.2 5.5 10.2 15.5 9.1 3.0 11.6 2.5 5.5 15.0 5.5 9.8 4.6 6.3 6.2 3.7 14.8 3.7 7.6 7.0 6.2 7.5 2.6 32.9 3.7 5.8 6.9 3.6 12.1 5.2 2.6 12.1 6.0 9.4 4.5 6.6 5.1 6.8 8.1 5.3 4.7 9.7 3.7 3.2 8.7 8.2 5.4 4.7 6.0 3.4 3.2 3.6 5.2 2.7 5.8 6.5 4.1 4.8 2.7 2.6 7.1 1.8 3.9 3.4 4.4 4.1 1.8 5.6 7.5 7.9 2.5 2.7 5.5 3.3 31.8 5.8 8.0 2.4 8.7 9.2 1.6 18.9 7.5 3.3 0.0 5.7 1.5 9.1 17.7 8.7 2.9 7.5 6.8 11.7 6.4 3.6 3.0 2.7 5.2 6.4 2.6 7.2 5.1 1.7 5.4 22.4 4.5 8.0 10.7 7.2 1.9 3.9 6.0 10.6 6.1 6.2 1.3 2.6 5.9 1.3 2.4 2.9 1.9 1.5 1.8 2.6 1.5 2.2 1.8 14.6 1.7 2.0 1.8 1.9 1.8 4.7 4.6 5.2 5.5 4.6 6.3 7.6 7.0 5.8 6.6 5.3 5.4 75.2 16.0 32.6 21.2 21.8 7.9 13.5 6.6 7.4 29.5 8.8 8.8 8.0 8.6 18.0 1.8 62.6 5.8 14.0 12.6 3.9 15.3 51.4 146.1 30.4 61.3 17.4 5.5 21.8 8.6 9.5 11.8 9.2 21.0 20.3 73.5 121.7 9.7 7.8 35.3 20.0 13.5 10.2 16.2 8.4 9.1 7.8 14.5 5.4 18.7 15.5 9.4 14.4 9.0 17.1 9.9 8.9 4.5 11.0 10.2 5.0 3.1 119.2 85.7 0.0 23.1 12.9 24.9 25.3 4.8 5.8 8.2 17.2 6.6 8.9 11.2 RPGRIP1 "CORD13, LCA6, RGI1, RPGRIP" ENSG00000092200 "RPGR interacting protein 1" Q96KN7 14 21280083-21351301 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Glaucoma, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 80 "retina: 185.3;testis: 59.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 231.4;Early spermatids: 177.3;Late spermatids: 108.9;Rod photoreceptor cells: 117.5;Spermatocytes: 51.7" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 8.8" "Group enriched" "Detected in many" 18 "dendritic cells: 3.3;granulocytes: 8.8;monocytes: 3.7" "Cell line enhanced" "Detected in some" "RT4: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042955, HPA060190" Supported Supported NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042955: AB_2678239, HPA060190: AB_2684218" "unprognostic (9.02e-4)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" "unprognostic (1.86e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (2.92e-1)" "unprognostic (1.99e-1)" "unprognostic (3.94e-3)" "unprognostic (2.33e-1)" "unprognostic (7.31e-3)" "unprognostic (2.86e-2)" "unprognostic (2.87e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-2)" 0.2 0.1 0.5 0.7 0.3 1.2 0.6 0.8 0.6 0.3 0.4 0.5 0.9 0.2 0.0 0.2 0.1 0.3 0.2 0.4 0.3 0.2 0.8 0.5 0.5 0.4 0.2 0.1 0.1 0.2 0.1 1.2 0.6 0.4 0.6 185.3 0.1 0.1 0.1 0.5 0.8 0.0 0.1 1.5 0.2 59.6 0.5 0.1 0.3 0.2 0.3 0.5 0.1 0.3 0.3 0.8 0.8 0.4 0.0 0.0 1.1 0.3 0.0 0.0 0.4 0.5 0.5 1.1 0.2 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.5 0.4 0.8 0.2 0.0 0.9 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.8 0.7 0.1 0.0 0.3 0.3 0.5 1.2 0.5 0.3 0.4 0.7 0.9 0.0 3.8 0.6 0.5 0.7 0.8 0.2 0.6 0.3 0.5 0.3 0.2 0.2 0.8 0.6 0.9 0.9 1.0 0.4 0.6 0.2 0.7 3.7 0.0 0.0 1.7 0.1 0.0 0.0 0.0 3.3 0.1 0.1 0.0 8.8 0.3 0.0 0.0 0.0 1.0 0.5 0.3 0.8 0.6 0.4 0.3 0.4 0.2 0.6 0.1 0.5 0.3 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.2 0.3 1.0 0.0 0.0 0.0 231.4 0.9 0.0 0.0 0.0 0.0 177.3 0.1 0.1 0.6 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.9 0.0 1.2 0.0 0.0 2.7 0.9 108.9 1.8 0.8 0.0 1.0 0.5 4.8 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.7 117.5 0.0 0.1 0.1 51.7 2.2 0.0 0.1 1.5 0.1 0.1 0.0 0.1 RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 207 "retina: 213.7" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 160.6;Rod photoreceptor cells: 162.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA059546: AB_2684058" "unprognostic (8.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.80e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.77e-3)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.06e-1)" "unprognostic (3.06e-2)" "unprognostic (5.12e-2)" "unprognostic (2.04e-4)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 213.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 6.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 1.9 0.0 0.0 0.0 160.6 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 SAG "ARRESTIN, RP47" ENSG00000130561 "S-antigen visual arrestin" P10523 2 233307816-233347055 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital stationary night blindness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 474 "retina: 1466.0" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 6946.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA004946 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA004946: AB_2667304" "unprognostic (4.76e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (3.95e-1)" "unprognostic (8.54e-2)" "unprognostic (2.89e-2)" "unprognostic (3.86e-2)" "unprognostic (2.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.54e-1)" "unprognostic (4.57e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-9)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-5)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1466.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 1.6 0.2 0.0 651.7 0.2 0.3 1.0 0.0 0.0 0.0 869.5 1.5 0.7 0.6 0.0 0.0 40.4 0.9 0.2 41.6 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 338.2 0.5 0.0 0.0 1.5 2.3 121.5 0.9 0.5 0.0 0.0 0.7 1191.9 0.0 0.5 0.2 0.0 0.0 0.0 0.4 1.2 0.9 0.0 0.2 6946.1 13.1 1.7 0.4 2.1 1.6 0.0 0.6 0.4 0.9 0.1 0.2 1.2 SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 13.3;Granulosa cells: 37.2;Peritubular cells: 45.5;Theca cells: 14.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 49.8;THP-1: 20.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003190 Approved "Secreted to blood" NA NA 2170000 190000 "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA003190: AB_1079882" "unprognostic (5.29e-2)" "unprognostic (7.15e-6)" "unprognostic (6.03e-3)" "unprognostic (8.33e-2)" "unprognostic (3.65e-1)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (1.02e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-3)" 1.8 6.1 0.8 0.8 1.1 0.1 1.2 0.1 1.4 0.9 4.1 3.8 5.9 1.1 0.1 3.6 1.2 0.8 0.2 0.6 3.8 3.5 5.1 6.8 0.0 1.7 10.2 26.4 0.1 9.1 3.8 2.6 7.0 1.9 2.0 0.4 3.6 0.5 9.6 0.6 7.7 0.5 0.3 5.7 7.0 7.1 1.2 0.1 3.1 1.9 0.0 3.3 0.7 0.4 0.0 0.0 2.2 7.8 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.1 0.1 0.3 0.1 0.7 0.0 0.0 0.1 0.7 0.0 0.1 0.7 0.2 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.3 0.1 20.4 0.0 0.3 0.2 0.6 0.0 2.1 4.3 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.1 1.4 0.6 3.8 1.7 10.2 7.0 0.3 1.2 0.4 0.2 9.6 1.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.9 0.1 1.4 0.0 0.6 0.0 0.0 0.2 0.2 0.0 1.9 0.1 3.0 1.3 1.2 1.3 0.0 0.0 0.4 0.0 13.3 2.6 0.5 3.4 1.3 37.2 0.4 1.9 0.8 0.0 0.3 0.2 0.0 0.0 0.4 4.6 7.8 0.2 0.0 0.0 0.1 4.1 0.0 0.0 0.3 0.1 0.0 45.5 0.4 0.0 0.0 0.4 0.7 0.2 0.0 0.4 1.2 3.8 2.0 0.0 0.1 0.4 2.8 14.3 0.0 0.1 SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.5;Inhibitory neurons: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064095, HPA065969" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA064095: AB_2732710, HPA065969: AB_2685590" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" 3.2 2.3 5.4 0.9 7.0 0.4 3.2 3.2 8.2 4.1 0.1 2.5 0.5 3.6 1.7 1.3 3.3 0.8 2.7 8.0 6.3 3.5 1.0 2.5 1.5 4.2 2.1 5.3 2.6 3.0 7.2 0.9 3.9 3.1 1.0 4.7 2.7 1.4 1.4 1.9 2.1 1.6 1.5 2.6 2.2 4.1 8.1 1.2 3.1 1.3 1.4 2.6 3.2 3.8 6.1 3.4 3.7 5.5 5.8 3.3 2.6 3.9 8.9 7.4 6.5 1.4 3.3 2.3 5.0 6.2 14.4 1.9 6.7 5.7 7.5 5.3 7.0 4.4 1.4 3.8 2.3 1.0 5.4 2.6 6.0 4.9 2.4 14.1 2.9 4.4 0.2 0.2 4.8 2.1 3.3 0.8 2.6 2.7 4.0 0.0 5.4 0.0 6.0 2.6 2.9 5.8 7.0 1.8 6.5 5.0 2.6 0.7 4.9 11.5 5.8 2.9 7.1 5.2 5.6 0.3 13.4 0.3 5.6 0.3 0.1 0.7 1.9 0.0 1.2 1.1 1.1 1.7 0.0 0.8 1.1 1.3 0.3 1.0 0.2 0.0 0.9 0.8 5.4 7.0 3.2 8.2 8.0 6.3 4.2 2.1 3.9 1.5 8.1 3.8 2.2 0.0 6.5 4.9 2.7 0.4 1.8 1.8 2.2 8.8 1.8 2.5 2.4 5.7 4.8 5.5 12.5 0.8 1.4 0.7 1.9 2.1 3.2 0.6 0.6 2.2 7.2 0.8 44.5 1.6 2.4 3.3 1.5 1.0 2.5 3.0 3.3 0.6 0.8 11.8 22.7 0.6 2.0 0.0 0.7 3.7 0.9 0.7 0.0 4.7 1.5 3.3 4.1 4.5 5.8 2.7 1.4 1.5 0.7 1.3 0.4 0.3 1.3 6.7 6.6 3.1 1.4 5.6 11.2 0.5 0.4 0.4 3.5 0.5 1.0 1.6 SIX6 "OPTX2, Six9" ENSG00000184302 "SIX homeobox 6" O95475 14 60509146-60512850 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pituitary gland: 28.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 29.2;Horizontal cells: 48.8;Muller glia cells: 160.9" "Cancer enriched" "Detected in single" 8 "glioma: 1.0" "Group enriched" "Detected in some" 18 "hypothalamus: 3.9;thalamus: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 13.4;MOLT-4: 44.0" "Region enriched" "Detected in single" 14 "hypothalamus: 3.6" "Region enriched" "Detected in single" 12 "hypothalamus: 1.6" HPA001403 Approved Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA001403: AB_1079993" "unprognostic (2.76e-1)" "unprognostic (6.14e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.1 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 44.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.0 1.3 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 1.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SLC13A4 "SUT-1, SUT1" ENSG00000164707 "Solute carrier family 13 member 4" Q9UKG4 7 135681237-135729258 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "choroid plexus: 809.0" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 786.0" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Region enhanced" "Detected in many" "hippocampal formation: 45.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048582 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA048582: AB_2680450" "unprognostic (2.40e-1)" "unprognostic (2.51e-1)" "unprognostic (9.70e-3)" "unprognostic (1.78e-1)" "unprognostic (7.69e-2)" "unprognostic (3.96e-6)" "unprognostic (3.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.56e-3)" "unprognostic (9.23e-2)" "unprognostic (2.89e-1)" "unprognostic (1.87e-1)" "unprognostic (2.30e-6)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (2.00e-1)" "unprognostic (6.73e-2)" 0.0 0.0 1.6 0.0 0.7 0.0 0.0 9.2 3.4 0.7 809.0 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.1 45.4 0.7 0.0 0.0 0.0 0.0 0.9 1.7 0.0 0.2 0.0 1.4 54.4 0.6 0.0 0.0 2.3 0.5 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 3.9 12.9 0.0 0.0 0.0 2.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 30.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.1 0.0 2.4 0.1 0.1 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 9.2 3.4 45.4 0.7 0.9 1.7 0.6 0.7 12.9 0.9 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.1 0.0 3.4 0.1 0.1 1.9 0.0 0.1 0.0 4.2 189.9 0.0 0.0 0.0 0.2 0.6 0.5 0.5 1.0 0.0 0.0 2.7 0.0 9.5 1.2 0.0 0.1 0.0 0.1 0.0 0.0 14.9 3.3 3.0 0.0 0.0 0.0 0.3 0.5 0.3 0.4 0.0 1.0 0.0 2.1 0.0 3.5 2.5 0.1 0.0 0.0 0.1 0.5 0.0 0.1 4.3 14.9 0.0 0.6 0.3 0.3 0.5 0.0 0.1 786.0 0.1 0.1 0.0 0.4 SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084093 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.1" "Cell type enhanced" "Detected in some" "Leydig cells: 4.4;Melanocytes: 5.4;Oligodendrocytes: 4.0;Spermatogonia: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;SiHa: 2.1;T-47d: 1.3;U-2 OS: 1.2;U-266/70: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" 0.5 0.3 1.1 0.0 3.3 0.2 0.6 0.2 6.0 0.7 0.0 0.3 0.1 0.4 0.0 0.3 0.9 0.1 0.6 0.8 1.1 0.4 0.2 0.3 0.0 4.0 1.4 0.3 0.4 0.0 1.6 0.0 3.6 1.7 0.0 0.1 1.2 0.0 0.5 0.7 0.2 0.0 0.3 0.3 0.4 0.8 2.8 0.0 0.7 0.0 0.0 0.4 0.7 9.1 0.3 0.0 0.1 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.4 0.1 2.1 0.0 0.2 0.1 1.3 0.0 0.0 0.0 1.2 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.3 0.2 6.0 0.8 1.1 4.0 1.4 3.6 0.3 2.8 9.1 0.6 0.0 0.0 0.7 0.0 1.3 0.5 0.6 0.6 0.1 0.6 0.8 0.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.3 0.1 0.9 0.2 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.0 1.7 0.7 0.1 1.0 0.0 0.4 0.2 0.0 0.8 1.4 2.5 4.4 0.7 5.4 0.0 0.0 1.4 0.0 0.5 4.0 0.3 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 1.5 2.4 2.1 7.7 0.5 0.9 0.0 0.3 0.6 0.1 0.7 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC24A1 "CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX" ENSG00000074621 "Solute carrier family 24 member 1" O60721 15 65611366-65660995 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Symport, Transport, Vision" "Congenital stationary night blindness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 34 "retina: 193.5" "Cell type enriched" "Detected in many" 11 "Rod photoreceptor cells: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039370 Enhanced Approved Microtubules NA NA "Cluster 6: Non-specific - Transcription" "Cluster 79: Retina - Phototransduction" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA039370: AB_10960279" "unprognostic (9.47e-2)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.66e-3)" "unprognostic (6.39e-3)" "unprognostic (4.64e-1)" "unprognostic (8.82e-2)" "unprognostic (1.86e-1)" "unprognostic (4.69e-2)" "unprognostic (3.94e-1)" "unprognostic (2.01e-1)" "unprognostic (9.91e-2)" "prognostic favorable (2.33e-6)" "unprognostic (8.45e-2)" "unprognostic (9.22e-2)" "unprognostic (3.04e-2)" "unprognostic (1.96e-2)" 4.0 3.0 2.4 1.9 2.2 1.8 4.9 5.7 2.7 4.8 2.5 2.6 2.2 3.8 4.7 2.4 5.1 3.8 1.6 2.1 2.1 5.1 2.9 3.1 3.3 2.3 2.3 5.4 2.9 3.8 2.7 3.6 2.3 3.2 2.4 193.5 2.6 3.1 1.0 5.1 3.0 2.9 2.3 3.9 2.5 4.1 2.1 2.4 5.1 1.3 1.8 3.0 3.2 2.5 1.5 3.0 3.2 2.9 4.7 7.9 4.0 3.7 4.2 3.7 2.4 1.4 6.5 2.1 12.4 3.7 1.3 4.1 3.9 4.2 2.1 2.2 2.8 4.6 2.5 6.8 6.8 3.1 6.0 6.7 5.9 2.1 12.3 5.1 6.4 4.8 5.0 7.0 6.0 6.4 2.0 2.8 4.1 13.5 1.2 2.0 1.0 1.4 5.6 6.0 1.5 2.1 1.0 2.8 8.0 4.4 6.0 4.2 9.3 3.7 3.7 1.4 2.6 2.8 5.5 2.4 3.9 6.4 3.1 2.6 0.4 0.7 0.4 0.4 0.5 0.4 0.4 0.4 0.3 1.0 0.3 0.4 0.6 0.8 0.2 0.8 0.1 0.1 2.4 2.2 5.7 2.7 2.1 2.1 2.3 2.3 2.3 2.3 2.1 2.5 4.0 6.4 5.1 5.2 3.4 1.5 1.4 1.2 1.8 29.8 3.5 2.8 2.3 0.0 3.8 0.0 27.1 4.2 1.6 2.9 0.0 1.5 1.6 6.3 5.4 15.6 1.8 1.7 2.2 1.3 2.7 2.6 4.1 7.9 2.5 4.7 3.6 1.4 1.9 20.2 2.0 2.5 2.0 3.1 1.6 2.5 3.1 2.7 1.8 4.7 1.2 26.1 2.1 3.0 1.4 2.6 0.5 2.2 3.3 1.4 2.6 0.7 4.1 338.3 0.0 3.4 2.5 20.3 10.1 2.9 1.0 2.5 2.5 8.3 2.6 0.9 SLC32A1 "bA122O1.1, VGAT, VIAAT" ENSG00000101438 "Solute carrier family 32 member 1" Q9H598 20 38724486-38729372 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 39.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.7;Horizontal cells: 58.9;Inhibitory neurons: 20.7" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037156, HPA058859, HPA059985" Enhanced Supported Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "CAB037156: AB_532294, HPA058859: AB_2683836, HPA059985: AB_2684187" "unprognostic (1.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" 0.0 0.0 12.4 0.0 39.8 0.2 0.0 3.4 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 36.5 0.3 0.0 0.0 0.0 14.2 6.8 0.0 0.0 0.0 7.6 0.0 8.7 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.4 39.8 3.4 22.0 2.4 36.5 14.2 6.8 8.7 6.3 5.1 1.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 14.7 0.0 0.0 0.4 0.0 0.1 0.0 4.2 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.9 20.7 0.0 0.0 0.0 0.4 0.6 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 3.1 0.0 0.0 0.1 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC6A6 TAUT ENSG00000131389 "Solute carrier family 6 member 6" P31641 3 14402576-14489349 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 68.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 571.3;Rod photoreceptor cells: 547.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 59.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 59.2" "Cell line enhanced" "Detected in many" "HeLa: 66.6;RPTEC TERT1: 111.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015028, HPA016488" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions, Cytosol" "HPA015028: AB_1857200, HPA016488: AB_1857202" "unprognostic (8.25e-2)" "unprognostic (7.29e-3)" "unprognostic (2.63e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (5.75e-8)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.58e-1)" "unprognostic (2.56e-1)" "unprognostic (3.81e-1)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-2)" "unprognostic (9.65e-2)" "unprognostic (1.90e-1)" 10.9 25.6 1.7 8.4 6.9 54.7 8.5 5.0 7.7 11.3 0.0 3.9 0.9 10.4 0.0 6.7 6.7 9.4 24.4 3.5 3.8 12.2 1.5 20.5 7.5 9.6 6.6 28.9 2.3 2.5 7.4 7.9 6.7 4.3 2.4 68.5 17.1 7.2 30.9 18.3 17.1 6.9 1.7 15.6 9.4 3.7 11.0 4.5 9.3 8.7 9.1 8.1 6.1 6.8 4.1 18.4 4.6 10.1 11.6 5.7 15.9 4.3 26.4 8.4 6.2 8.8 5.6 12.6 4.5 10.9 11.7 4.3 4.5 10.1 16.5 3.7 9.7 8.8 66.6 24.2 0.0 3.7 22.3 1.9 2.6 7.8 1.6 7.7 14.5 6.2 10.1 3.5 18.6 8.1 9.4 20.3 6.1 7.1 10.8 6.1 7.3 24.9 111.8 28.5 7.2 4.6 3.1 3.2 0.6 36.8 11.5 4.5 15.3 9.7 3.9 5.2 6.2 3.9 6.0 7.1 19.3 6.6 23.2 5.6 9.2 8.6 2.5 7.3 1.3 4.0 2.7 3.0 2.8 2.1 0.5 0.6 59.2 1.8 9.4 1.4 8.7 4.6 1.7 6.9 5.0 7.7 3.5 3.8 9.6 6.6 6.7 1.7 11.0 6.8 42.7 6.4 21.5 1.3 16.4 49.3 17.1 51.5 43.9 126.1 9.5 6.9 4.2 7.2 52.8 20.2 571.3 3.0 14.5 0.5 0.0 12.0 19.6 82.1 23.0 29.4 14.4 9.4 17.4 8.2 15.8 13.5 29.0 126.9 13.3 2.5 11.7 0.6 27.2 10.1 18.5 3.5 46.8 60.1 59.5 16.6 17.4 58.8 17.8 32.8 110.9 30.8 10.3 3.0 23.9 31.1 12.6 17.3 13.3 17.6 51.3 23.3 69.5 547.8 0.0 11.4 8.3 0.4 1.3 15.7 23.9 5.1 25.5 46.8 3.6 16.8 SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.0" "Group enriched" "Detected in many" 9 "Early spermatids: 946.9;Late spermatids: 1152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038082, HPA038083" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA038082: AB_10671738, HPA038083: AB_10671519" "unprognostic (2.09e-2)" "unprognostic (6.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.50e-3)" "unprognostic (3.22e-2)" "unprognostic (6.75e-2)" "unprognostic (1.29e-3)" "unprognostic (4.70e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-3)" "prognostic favorable (4.16e-5)" "unprognostic (2.88e-1)" "prognostic favorable (2.50e-5)" "unprognostic (8.41e-2)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (2.81e-2)" 5.8 6.0 8.6 1.6 10.4 1.7 6.0 28.4 9.5 7.2 6.7 5.8 2.2 6.6 7.0 2.8 8.3 5.5 5.4 8.6 10.4 9.5 5.1 4.6 1.8 8.6 9.2 12.3 7.9 7.6 11.1 2.8 8.6 6.6 3.1 10.2 4.1 4.6 5.0 5.6 3.2 4.7 8.9 3.6 5.0 57.0 9.2 3.0 12.1 4.5 1.2 5.4 4.9 11.2 2.3 3.7 5.5 7.5 8.8 16.5 6.0 5.2 9.3 5.1 3.4 1.2 4.5 2.2 2.5 5.7 3.8 2.3 2.5 4.0 4.8 3.2 1.8 0.5 1.9 2.1 12.7 3.9 0.5 7.8 6.6 2.1 3.9 16.8 9.4 5.0 1.3 2.7 4.8 2.8 2.8 3.7 1.4 2.9 4.6 3.9 5.6 1.3 8.1 1.9 3.9 4.9 5.1 6.7 5.0 6.5 6.0 4.2 4.9 3.7 4.0 5.2 2.9 2.6 2.1 1.3 6.2 1.1 2.6 0.0 1.0 0.2 2.1 1.4 2.5 1.9 1.7 1.0 2.1 0.4 1.0 1.8 0.8 0.4 0.9 2.1 0.7 1.0 8.6 10.4 28.4 9.5 8.6 10.4 8.6 9.2 8.6 8.9 9.2 11.2 7.8 12.8 7.3 38.5 1.5 2.4 7.6 9.8 7.4 10.8 6.3 8.5 12.0 7.2 8.8 3.7 20.9 2.6 5.3 1.1 9.8 11.0 946.9 22.3 13.2 6.8 16.3 1.3 113.0 7.2 3.6 11.8 4.1 4.2 1.3 19.4 7.9 4.5 5.7 15.2 91.6 4.0 12.2 17.2 2.8 1152.6 20.5 6.7 8.8 25.3 4.0 12.5 2.1 49.8 54.7 5.6 4.3 17.0 0.9 3.0 1.4 26.0 32.7 20.5 6.6 15.0 7.9 37.5 14.7 3.0 2.0 1.1 3.3 20.5 4.5 3.3 SPTBN5 "BSPECV, HUBSPECV, HUSPECV" ENSG00000137877 "Spectrin beta, non-erythrocytic 5" Q9NRC6 15 41848146-41894053 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 8.8;retina: 26.9" "Group enriched" "Detected in many" 22 "Cone photoreceptor cells: 210.6;Rod photoreceptor cells: 211.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.7;SCLC-21H: 5.1;TIME: 13.6;WM-115: 4.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "spinal cord: 3.6" HPA055283 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA055283: " "unprognostic (5.46e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-2)" "unprognostic (5.84e-3)" "unprognostic (1.12e-1)" "unprognostic (6.84e-3)" "unprognostic (6.40e-3)" "unprognostic (2.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.37e-2)" "unprognostic (1.11e-2)" 1.0 0.3 0.4 0.7 1.3 0.4 1.1 8.8 1.4 0.6 0.1 0.5 0.3 0.4 0.8 1.7 0.5 0.9 2.0 0.6 0.1 1.7 1.6 1.2 0.6 0.8 0.3 0.6 1.1 0.5 1.9 0.2 1.0 1.6 0.2 26.9 2.7 0.3 0.4 1.7 0.5 0.2 0.1 0.5 1.0 0.8 0.1 0.0 2.1 0.4 0.1 2.6 0.7 0.8 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.8 0.0 1.5 0.4 0.0 0.2 0.0 0.8 0.1 0.0 1.6 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 0.3 1.4 5.1 0.1 0.2 0.4 0.1 0.4 0.8 0.0 13.6 0.0 1.3 0.3 1.7 1.5 2.3 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 8.8 1.4 0.6 0.1 0.8 0.3 1.0 0.1 0.1 0.8 1.9 0.0 2.4 2.9 0.2 0.8 0.9 0.4 1.2 7.9 1.8 2.0 4.0 0.0 1.5 0.0 210.6 0.1 0.8 0.7 0.0 0.5 1.1 1.1 0.3 3.7 0.0 0.0 2.3 0.2 0.3 0.6 2.0 3.8 1.3 1.0 0.4 0.5 2.0 3.3 0.5 0.5 0.0 0.0 0.6 0.9 0.0 1.0 1.8 0.0 0.8 9.6 1.0 6.0 0.5 1.0 1.4 0.0 0.9 0.2 0.2 0.6 0.8 211.8 0.0 0.2 0.3 0.5 0.5 3.9 1.3 0.0 0.5 0.2 0.6 1.0 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TMEM221 ENSG00000188051 "Transmembrane protein 221" A6NGB7 19 17435509-17448668 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 7.9;retina: 9.4" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 14.6;Muller glia cells: 49.2;Rod photoreceptor cells: 24.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.6;PC-3: 6.8;REH: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041580, HPA062945" Supported Approved "Nuclear membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane" "HPA041580: AB_10795700, HPA062945: " "unprognostic (3.60e-2)" "unprognostic (7.86e-2)" "unprognostic (4.51e-4)" "unprognostic (2.09e-2)" "unprognostic (2.61e-2)" "unprognostic (9.14e-3)" "unprognostic (3.19e-1)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.20e-2)" "unprognostic (1.98e-1)" "unprognostic (9.47e-4)" "unprognostic (2.37e-2)" "unprognostic (6.67e-2)" "unprognostic (2.76e-1)" "unprognostic (2.42e-2)" "unprognostic (1.23e-1)" 0.6 4.2 3.6 0.2 3.6 0.1 1.2 3.2 4.4 0.8 2.7 0.7 0.1 0.6 0.7 0.5 2.7 0.2 0.6 3.7 3.2 0.6 0.4 0.3 0.2 3.6 3.1 7.9 2.2 5.4 1.7 0.1 3.1 1.3 0.0 9.4 0.8 1.0 0.2 0.4 0.4 0.1 3.4 0.4 0.4 0.5 3.8 0.5 0.7 0.1 0.1 0.4 1.0 3.4 0.5 1.5 0.6 4.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.4 0.2 1.3 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 1.0 0.3 6.8 3.9 0.1 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.2 4.4 3.7 3.2 3.6 3.1 3.1 3.4 3.8 3.4 0.5 0.0 0.5 1.0 0.1 0.0 0.1 0.0 0.0 1.3 0.3 0.3 0.3 1.5 0.0 0.0 14.6 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 2.0 0.0 0.0 2.2 0.0 0.2 0.0 0.2 3.3 0.0 3.7 1.7 3.9 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.1 49.2 0.0 0.0 0.2 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.5 0.4 0.2 0.5 0.0 0.1 0.0 0.0 0.2 0.1 0.1 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 UNC119 "HRG4, POC7, POC7A" ENSG00000109103 "Unc-119 lipid binding chaperone" Q13432 17 28546708-28552631 "Disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 20 "retina: 1168.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 671.1;Cone photoreceptor cells: 856.9;Muller glia cells: 301.5;Rod photoreceptor cells: 2038.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041912 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041912: AB_10795267" "unprognostic (8.93e-2)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (4.95e-3)" "unprognostic (2.10e-1)" "unprognostic (1.44e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.76e-3)" "prognostic favorable (8.09e-5)" "unprognostic (2.65e-1)" "unprognostic (8.08e-3)" "unprognostic (5.51e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (9.82e-4)" "unprognostic (1.71e-3)" 17.7 29.3 48.1 23.6 47.8 55.9 20.7 44.0 59.2 25.9 54.7 19.9 12.0 21.3 17.8 25.3 19.1 14.3 24.5 49.7 49.5 36.6 32.9 21.1 29.7 49.3 45.9 21.3 24.5 22.2 28.8 11.0 49.7 29.8 10.9 1168.7 26.7 20.1 6.1 32.6 26.0 13.7 43.9 55.5 20.3 53.1 51.4 17.5 23.1 6.2 29.6 22.9 25.9 45.6 24.9 30.7 30.0 42.0 31.1 30.2 14.7 20.0 27.4 35.7 33.4 42.7 8.1 20.2 21.2 30.9 24.5 39.7 25.6 29.8 19.0 37.6 47.8 14.0 15.5 13.2 21.3 20.9 42.1 27.8 40.4 25.7 12.7 33.4 28.9 21.5 14.6 16.3 22.1 39.1 20.8 20.8 29.3 21.0 21.9 32.8 49.2 9.0 27.2 27.2 11.7 41.1 28.8 46.4 31.1 34.5 36.7 35.7 22.1 20.4 38.5 33.3 19.8 18.6 20.7 4.6 33.7 33.5 19.1 21.6 48.7 120.2 8.9 122.1 8.9 29.1 16.9 13.7 82.3 42.6 18.7 13.4 131.5 18.2 212.4 93.4 16.5 36.3 48.1 47.8 44.0 59.2 49.7 49.5 49.3 45.9 49.7 43.9 51.4 45.6 10.4 0.0 5.4 5.2 34.5 13.4 16.3 38.8 34.1 671.1 25.2 33.8 12.6 18.6 17.9 12.9 856.9 25.3 48.7 22.9 33.2 20.4 3.0 5.5 8.4 24.0 25.3 4.8 8.8 18.3 9.0 13.6 11.2 7.8 12.7 14.1 8.9 13.8 34.6 146.4 11.3 14.3 34.6 41.0 89.8 6.6 14.6 44.6 19.6 4.7 56.8 301.5 59.8 4.5 1.2 17.8 16.4 21.4 19.6 22.1 23.8 20.6 6.7 2038.5 46.0 6.6 15.8 1.5 16.6 20.6 14.3 20.0 25.3 14.1 13.7 18.9 VAT1L KIAA1576 ENSG00000171724 "Vesicle amine transport 1 like" Q9HCJ6 16 77788564-77980107 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "adrenal gland: 70.1;brain: 186.9;choroid plexus: 232.4;retina: 188.7" "Group enriched" "Detected in some" 4 "Horizontal cells: 297.8;Muller glia cells: 106.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.1;BJ hTERT+: 68.7;fHDF/TERT166: 38.1;NTERA-2: 79.9;U-87 MG: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044061, CAB046032, HPA061138" Enhanced Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB046032: AB_11126308, HPA044061: AB_10959610, HPA061138: " "unprognostic (1.49e-2)" "unprognostic (8.74e-3)" "unprognostic (8.80e-3)" "unprognostic (3.39e-2)" "unprognostic (3.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (8.57e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.01e-6)" "unprognostic (2.50e-2)" "unprognostic (6.53e-2)" "unprognostic (1.19e-1)" "unprognostic (5.96e-2)" 1.8 70.1 30.0 3.3 38.1 0.8 0.5 45.7 24.1 0.7 232.4 3.6 2.3 5.4 6.8 1.7 0.9 4.0 15.2 19.6 186.9 5.3 1.0 0.3 0.4 60.2 53.2 0.3 1.8 0.7 4.5 1.9 84.0 0.3 5.6 188.7 1.4 0.4 0.2 0.1 3.2 2.5 49.9 0.0 1.9 1.9 67.4 0.1 2.4 0.3 2.3 1.4 1.2 37.4 0.0 0.0 23.1 0.0 7.8 0.0 0.0 2.8 68.7 0.9 0.7 0.0 0.0 0.0 0.0 38.1 0.7 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.5 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.4 79.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.0 3.7 0.0 1.1 0.0 14.1 0.1 18.6 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 82.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 38.1 45.7 24.1 19.6 186.9 60.2 53.2 84.0 49.9 67.4 37.4 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 7.0 0.1 0.5 9.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.2 4.4 0.0 0.2 0.9 3.0 0.0 20.7 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.0 0.2 297.8 31.3 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 1.0 0.6 106.9 0.0 44.7 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 VSX2 "CHX10, HOX10, RET1" ENSG00000119614 "Visual system homeobox 2" P58304 14 74239449-74262738 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding, Repressor" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 43 "retina: 73.6" "Group enriched" "Detected in some" 10 "Bipolar cells: 152.4;Muller glia cells: 86.0" "Cancer enriched" "Detected in single" 34 "testis cancer: 2.5" "Region enhanced" "Detected in some" "pons: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "midbrain: 1.3;pons and medulla: 1.7" "Region enhanced" "Detected in single" "pons: 1.7" HPA003436 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 56: Bipolar cells - Visual perception" "HPA003436: AB_1078523" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-1)" "unprognostic (3.21e-4)" "unprognostic (7.77e-2)" "unprognostic (8.39e-4)" "unprognostic (3.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 73.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.2 0.5 1.7 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 152.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.6 86.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0