Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
AKR1C1	"DD1, DDH, DDH1, HAKRC, MBAB"	ENSG00000187134	"Aldo-keto reductase family 1 member C1"	Q04828	10	4963253-4983283	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 623.2"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0"	"Cancer enhanced"	"Detected in many"		"liver cancer: 64.2;lung cancer: 53.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.5"	"Low lineage specificity"	"Detected in single"			"Group enriched"	"Detected in many"	8	"ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1"									"CAB047303, HPA068265"	Enhanced		Enhanced	"Endoplasmic reticulum,Cytosol"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Endoplasmic reticulum, Cytosol"		"CAB047303: , HPA068265: AB_2685966"	"unprognostic (1.54e-2)"	"prognostic favorable (3.05e-4)"	"unprognostic (4.04e-2)"	"unprognostic (8.38e-2)"	"unprognostic (3.18e-2)"	"unprognostic (7.05e-2)"	"prognostic unfavorable (1.56e-4)"	"unprognostic (1.70e-1)"	"unprognostic (1.63e-1)"	"unprognostic (8.38e-2)"	"unprognostic (4.65e-1)"	"unprognostic (1.82e-2)"	"prognostic favorable (8.03e-9)"	"unprognostic (1.19e-1)"	"unprognostic (1.22e-1)"	"unprognostic (5.72e-2)"	"unprognostic (6.30e-2)"	185.7	14.3	12.3	13.5	16.5	5.8	116.2	16.0	11.5	12.9	6.9	23.2	25.3	6.6	6.6	103.9	11.5	65.7	135.5	10.9	18.7	45.4	623.2	28.9	4.7	22.1	18.4	15.5	23.3	0.8	9.7	1.7	23.2	17.3	12.2	11.5	73.7	12.5	120.4	35.3	23.4	8.7	19.6	4.1	142.9	13.0	22.2	4.6	46.7	27.3	7.8	71.1	31.3	20.3	0.0	429.6	2.4	426.7	2988.3	358.2	0.2	13.7	95.9	5.4	4.1	8.4	0.5	0.0	6.1	97.7	72.5	3.6	1.6	22.4	2.5	0.1	0.2	12.6	65.6	5415.7	30.0	1.8	0.0	183.9	27.3	44.2	26.7	0.4	10.2	2.9	95.8	0.4	74.7	2.4	0.1	0.4	1.2	2297.1	1.5	0.1	0.8	4.2	24.3	81.4	0.4	1.7	23.8	0.7	0.8	1.3	0.5	7.8	85.3	36.0	2.3	97.6	4.5	1.6	0.5	0.3	129.3	12.1	0.9	1.5	0.0	0.3	0.5	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.1	0.4	0.3	0.1	0.0	0.2	0.1	0.2	12.3	16.5	16.0	11.5	10.9	18.7	22.1	18.4	23.2	19.6	22.2	20.3	21.6	67.3	34.4	2.0	2.4	21.2	27.8	253.8	262.4	3.1	7.6	1.0	3.2	284.5	144.5	62.5	0.0	0.1	0.2	5.9	13.7	67.0	24.0	3.3	1.7	17.1	1.8	52.6	3.4	328.0	0.1	176.3	139.1	4.6	4.5	0.8	21.0	597.7	0.4	0.0	3.1	6.8	20.3	16.1	15.6	9.9	151.6	3.3	106.7	13.1	4.6	51.5	0.0	4.5	0.5	120.2	3.6	147.4	0.4	41.3	20.2	61.9	72.2	4.5	0.0	16.4	24.3	1.9	1.1	229.3	20.5	0.1	2.1	6.4	20.3	306.0
AKR1C2	"BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD"	ENSG00000151632	"Aldo-keto reductase family 1 member C2"	P52895	10	4987400-5018031	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 341.5;liver: 481.9"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9"	"Group enriched"	"Detected in many"	6	"cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	5	"A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9"									"CAB047304, HPA068265"	Enhanced		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"CAB047304: , HPA068265: AB_2685966"	"unprognostic (6.77e-2)"	"unprognostic (8.88e-3)"	"unprognostic (3.02e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.72e-2)"	"unprognostic (2.86e-2)"	"unprognostic (8.65e-2)"	"unprognostic (5.03e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.02e-1)"	"unprognostic (6.25e-3)"	"unprognostic (8.58e-2)"	"unprognostic (1.09e-2)"	"unprognostic (8.60e-3)"	"unprognostic (1.46e-2)"	"unprognostic (8.30e-2)"	341.5	20.8	9.8	10.0	11.6	1.0	205.6	10.7	12.9	17.4	8.1	37.1	29.6	5.6	3.3	202.5	8.6	98.1	83.8	7.2	16.6	43.0	481.9	23.5	2.1	18.7	13.7	10.4	11.8	1.1	8.1	0.8	17.1	11.7	13.3	15.2	116.5	12.9	286.9	42.5	33.7	9.2	11.5	2.1	137.0	11.8	16.8	4.4	38.3	36.5	9.3	253.9	47.0	9.7	0.0	2054.8	2.4	214.1	2439.5	83.4	0.1	0.7	8.6	0.9	2.0	8.1	0.2	0.4	11.5	14.2	10.0	57.8	0.2	10.7	1.2	0.6	0.2	0.7	516.4	3926.2	4.6	0.4	0.9	218.3	126.4	10.5	10.4	0.7	0.9	0.3	81.9	0.3	20.4	3.3	0.2	0.0	0.7	2684.9	0.8	0.3	0.6	34.6	19.0	1178.9	1.2	0.4	21.2	0.3	0.1	0.4	0.5	4.0	8.6	5.1	1.8	74.6	0.8	0.6	0.6	0.3	25.9	30.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	9.8	11.6	10.7	12.9	7.2	16.6	18.7	13.7	17.1	11.5	16.8	9.7	15.2	12.8	2.8	0.0	0.9	11.9	9.5	141.7	20.5	1.9	0.8	1.4	5.5	102.9	128.8	0.0	0.0	0.0	0.0	10.3	0.0	18.3	17.3	0.7	0.5	7.5	1.8	8.0	2.6	103.3	0.1	44.2	133.5	0.8	0.0	0.1	10.8	397.4	0.1	3.3	4.2	5.4	46.8	12.0	7.8	7.8	79.2	1.0	8.8	19.7	0.6	39.6	0.0	5.5	0.3	90.0	6.6	78.6	0.8	23.7	15.9	3.6	40.3	3.0	0.0	5.3	13.9	0.2	0.3	112.9	13.5	0.0	1.3	0.4	8.5	271.9
AKR1C3	"DDX, HAKRB, HSD17B5, KIAA0119, PGFS"	ENSG00000196139	"Aldo-keto reductase family 1 member C3"	P42330	10	5035354-5107686	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 441.3"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8"	"Cancer enhanced"	"Detected in all"		"liver cancer: 83.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 244.0;gdT-cell: 102.6"	"Group enriched"	"Detected in many"	4	"granulocytes: 244.0;T-cells: 102.6"	"Cell line enhanced"	"Detected in many"		"A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2"									"CAB010874, HPA068265"	Enhanced		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA		19000000	"Cluster 38: Basophils - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 21: OE19 - Mitochondria"	"Cluster 1: Pancreatic cells - Digestion"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"CAB010874: AB_476751, HPA068265: AB_2685966"	"unprognostic (4.20e-3)"	"unprognostic (2.70e-2)"	"unprognostic (8.92e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.81e-3)"	"prognostic unfavorable (1.96e-4)"	"unprognostic (1.41e-1)"	"unprognostic (6.74e-2)"	"unprognostic (5.08e-2)"	"unprognostic (1.31e-1)"	"unprognostic (4.33e-2)"	"prognostic unfavorable (1.22e-4)"	"unprognostic (4.45e-1)"	"unprognostic (3.70e-2)"	"unprognostic (1.79e-3)"	"unprognostic (4.24e-3)"	164.4	50.2	31.1	25.4	34.6	42.3	115.2	32.1	42.4	21.9	30.2	185.9	441.3	25.9	4.4	53.2	42.1	261.1	42.9	31.5	35.6	177.7	268.0	48.3	7.6	30.3	33.9	17.8	36.4	22.5	10.4	4.7	32.3	10.3	98.0	19.1	40.5	19.4	116.9	27.0	270.9	39.2	30.3	3.8	237.4	10.0	31.5	37.4	26.4	34.8	6.6	84.7	22.2	31.1	0.1	1615.1	1.1	413.0	811.9	292.2	1.0	0.0	21.4	0.4	1.4	47.6	24.5	0.2	78.7	19.4	45.0	11.5	1.5	28.8	1.1	3.0	0.5	3.2	438.4	699.6	4.3	0.7	0.2	160.9	57.1	20.0	0.7	25.8	28.1	3.4	10.8	0.0	42.6	3.8	9.8	2.6	0.7	3025.3	4.3	3.3	9.6	43.7	149.0	639.2	1.0	2.9	232.2	0.0	0.3	0.9	0.5	0.2	221.7	5.2	4.7	87.8	3.1	0.7	0.7	0.3	45.8	62.8	4.4	244.0	2.9	4.8	102.6	0.9	6.9	0.0	19.0	18.7	2.1	0.5	11.6	8.9	7.3	21.1	1.4	39.6	21.4	42.4	31.1	34.6	32.1	42.4	31.5	35.6	30.3	33.9	32.3	30.3	31.5	31.1	144.2	44.8	5.3	4.9	4.3	12.0	3.7	393.1	2.8	2.0	15.8	5.5	3.9	0.0	172.9	36.8	0.0	0.4	64.4	133.8	43.0	114.6	3.3	67.5	4.5	67.5	19.2	34.9	2.5	722.5	0.0	44.3	158.0	66.4	5.7	0.1	0.0	0.0	1.6	1.7	3.2	65.9	61.1	0.0	14.0	4.9	78.3	14.8	21.4	7.5	4.1	132.7	202.9	14.6	0.0	266.1	219.6	106.8	3.1	1.3	576.9	601.8	112.8	5.3	26.3	15.5	20.3	0.5	4.3	20.2	10.7	0.0	14.4	7.8	196.9	46.4
AKR1C4	"3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581"	ENSG00000198610	"Aldo-keto reductase family 1 member C4"	P17516	10	5195462-5218949	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	17	"liver: 717.5"	"Cell type enriched"	"Detected in some"	16	"Hepatocytes: 613.3"	"Cancer enriched"	"Detected in some"	86	"liver cancer: 108.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"HDLM-2: 6.6;OE19: 2.9"									"HPA044720, HPA068265"	Uncertain		Approved	"Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol"		NA	NA		3800000		"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Cytosol"	"Nucleoli fibrillar center, Endoplasmic reticulum"	"HPA044720: AB_2679058, HPA068265: AB_2685966"	"unprognostic (2.21e-1)"	"unprognostic (3.04e-1)"	"unprognostic (5.15e-2)"	"unprognostic (1.25e-1)"		"unprognostic (5.99e-2)"	"unprognostic (9.40e-2)"	"unprognostic (2.32e-1)"		"unprognostic (1.26e-1)"	"unprognostic (1.52e-2)"		"unprognostic (1.29e-1)"	"unprognostic (3.31e-1)"	"unprognostic (7.34e-2)"		"unprognostic (1.45e-2)"	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	2.5	0.0	0.2	0.0	0.4	41.8	0.0	0.0	0.0	0.3	717.5	0.0	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.1	1.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.0	0.3	0.2	1.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	2.9	0.0	0.0	0.4	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	37.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.2	7.2	0.2	0.0	0.8	0.0	13.5	0.0	0.7	0.0	0.7	0.0	0.0	0.0	0.0	13.6	613.3	0.0	0.0	0.0	0.6	0.0	14.5	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.1	0.0	0.2	1.0	1.5	0.0	0.0	0.1	0.0	2.1	0.4	0.0	0.0	0.0	0.8	0.0	0.0	0.1
AKR1D1	SRD5B1	ENSG00000122787	"Aldo-keto reductase family 1 member D1"	P51857	7	138002324-138118305	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism"	Oxidoreductase	"Disease variant, FDA approved drug targets, Intrahepatic cholestasis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	83	"liver: 426.9"	"Group enriched"	"Detected in some"	31	"Early spermatids: 65.4;Hepatocytes: 110.3;Late spermatids: 126.1"	"Cancer enriched"	"Detected in single"	77	"liver cancer: 20.1"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	21	"Hep G2: 12.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA057002	Enhanced		Approved	Nucleoplasm,Cytosol		No	NA		61000	"Cluster 17: Basophils - Unknown function"	"Cluster 62: Liver - Hemostasis"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 2: Hepatocytes - Metabolism"	Nucleoplasm	Cytosol	"HPA057002: AB_2683308"	"unprognostic (2.38e-1)"	"unprognostic (1.65e-2)"			"unprognostic (1.02e-2)"	"unprognostic (1.52e-2)"	"prognostic favorable (9.91e-5)"	"unprognostic (6.11e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.30e-1)"	"unprognostic (6.87e-2)"	"unprognostic (2.94e-1)"	"unprognostic (9.68e-3)"	"unprognostic (2.90e-1)"	"unprognostic (5.80e-2)"	"unprognostic (3.11e-1)"	"unprognostic (1.67e-2)"	0.0	0.1	0.2	0.0	0.1	0.2	5.1	0.3	0.3	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.2	0.0	0.1	426.9	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.1	12.6	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.7	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.6	0.1	0.1	0.1	0.0	0.0	0.2	0.1	0.3	0.3	0.2	0.0	0.2	0.1	0.2	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.1	0.3	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	65.4	0.0	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.2	0.0	0.1	0.0	0.0	1.4	110.3	0.4	0.0	0.2	0.2	0.0	3.2	0.4	126.1	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.4	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.9	0.1	1.6	0.3	0.0	0.0	0.3	0.3	0.0	0.0	0.2
BCO2	"B-DIOX-II, BCDO2, FLJ34464"	ENSG00000197580	"Beta-carotene oxygenase 2"	Q9BYV7	11	112175510-112224699	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 47.2;liver: 52.3;retina: 55.9"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA061542	Supported					NA	NA			"Cluster 22: NK-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 9: Photoreceptor cells - Phototransduction"			"HPA061542: "	"unprognostic (2.92e-1)"	"unprognostic (1.89e-1)"	"unprognostic (3.76e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.91e-1)"	"unprognostic (1.50e-2)"	"unprognostic (7.60e-3)"	"unprognostic (1.88e-1)"	"unprognostic (3.18e-2)"	"unprognostic (6.40e-2)"	"unprognostic (2.39e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.36e-4)"	"unprognostic (2.31e-2)"	"unprognostic (9.86e-2)"	"unprognostic (1.07e-2)"	"unprognostic (1.34e-1)"	3.8	21.3	4.9	0.3	5.8	0.2	0.8	5.0	9.3	2.2	10.0	2.6	0.5	1.6	1.0	3.4	9.7	5.1	47.2	4.8	6.4	2.5	52.3	1.7	0.4	7.4	6.7	1.3	1.1	0.3	4.4	3.8	7.0	1.9	0.5	55.9	0.9	0.9	21.4	1.1	1.7	1.1	5.9	1.1	0.9	3.0	6.5	0.3	2.5	14.3	0.8	2.3	4.6	8.3	0.1	1.0	0.4	0.6	0.4	0.4	0.0	0.3	0.2	0.1	0.5	0.0	5.9	0.4	0.5	0.6	0.6	1.2	0.0	0.2	0.4	0.1	0.1	0.7	0.5	0.4	12.3	0.4	0.2	0.1	2.3	0.1	0.3	1.1	0.0	0.1	0.1	0.3	0.1	0.0	0.5	1.3	0.1	0.6	0.2	0.3	0.1	0.2	0.2	0.2	0.5	0.2	0.4	0.2	0.0	0.1	0.3	0.2	0.0	0.1	0.2	0.1	0.1	0.1	0.0	0.3	0.0	2.6	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.1	0.0	0.0	0.0	4.9	5.8	5.0	9.3	4.8	6.4	7.4	6.7	7.0	5.9	6.5	8.3	1.7	3.2	3.1	10.1	2.0	3.3	20.3	8.6	6.8	12.6	2.2	1.5	51.3	58.6	8.2	5.5	410.8	0.3	4.4	5.0	0.0	3.7	3.1	26.5	3.0	4.5	8.3	0.0	50.7	2.1	0.4	16.3	1.1	1.2	5.7	4.0	16.4	83.1	1.0	134.6	51.5	1.6	2.0	2.8	3.8	2.4	4.1	7.9	1.8	47.8	3.7	13.9	7.2	7.1	51.3	1.6	2.6	3.8	1.2	10.3	18.2	1.3	67.6	254.6	0.0	5.0	3.8	8.3	2.5	1.8	3.1	0.7	5.2	6.8	3.5	8.7
CYP17A1	"CPT7, CYP17, P450C17, S17AH"	ENSG00000148795	"Cytochrome P450 family 17 subfamily A member 1"	P05093	10	102830531-102837472	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Steroidogenesis	"Lyase, Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	84	"adrenal gland: 8229.5"	"Cell type enriched"	"Detected in some"	17	"Theca cells: 1871.0"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 22.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HMC-1: 3.0;SCLC-21H: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA048533	Enhanced		Approved	Vesicles	"Intracellular and membrane"	NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 52: Non-specific - Transcription"	Vesicles		"HPA048533: AB_2680432"	"unprognostic (1.07e-2)"	"unprognostic (8.84e-2)"	"unprognostic (3.01e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.91e-1)"	"unprognostic (6.29e-2)"	"unprognostic (2.92e-3)"	"unprognostic (2.39e-4)"	"unprognostic (8.26e-2)"	"unprognostic (2.35e-1)"	"unprognostic (5.92e-3)"	"unprognostic (1.13e-1)"	"prognostic favorable (5.43e-7)"	"unprognostic (1.07e-1)"	"unprognostic (5.56e-2)"	"unprognostic (1.66e-2)"	"unprognostic (2.94e-4)"	0.4	8229.5	0.0	2.1	0.0	0.0	0.4	0.1	0.1	1.1	0.0	0.5	0.0	0.8	0.1	0.9	1.0	0.4	1.0	0.0	0.0	52.9	6.7	1.4	0.0	0.0	0.1	16.6	1.7	10.5	0.7	0.0	0.0	0.7	0.0	0.2	3.4	0.0	1.0	0.7	0.6	0.0	0.0	0.9	1.3	98.3	0.0	0.0	2.9	0.0	0.0	0.8	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	2.2	0.1	0.4	0.1	0.0	0.5	0.0	0.1	0.7	0.0	0.0	1.8	0.0	0.4	0.1	0.1	21.5	0.0	41.6	0.1	0.0	0.7	0.0	2.7	0.1	0.2	0.0	1.3	0.0	0.1	0.0	0.1	0.4	6.1	0.1	1.7	0.1	0.0	0.0	0.6	0.7	10.6	1.8	0.9	0.0	0.0	0.1	0.2	3.1	0.5	0.1	0.7	0.0	0.0	0.0	0.3	0.0	104.3	0.0	1.2	0.0	1.2	0.6	0.3	0.1	0.0	0.0	0.3	0.4	1871.0	0.0	0.1
HSD17B1	"EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1"	ENSG00000108786	"Hydroxysteroid 17-beta dehydrogenase 1"	P14061	17	42552922-42555214	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	12	"placenta: 82.3"	"Group enriched"	"Detected in many"	4	"Granulosa cells: 1574.2;Syncytiotrophoblasts: 1495.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in many"	8	"BEWO: 399.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"HPA021032, HPA065296"	Enhanced		Supported	Cytosol		NA	NA		19000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 28: Placenta - Pregnancy"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 40: Granulosa cells - Unknown function"	Cytosol		"HPA021032: AB_1844345, HPA065296: AB_2685457"	"unprognostic (1.13e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.68e-2)"	"unprognostic (9.25e-2)"	"unprognostic (1.73e-1)"	"unprognostic (3.88e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (9.35e-2)"	"unprognostic (6.04e-2)"	"unprognostic (2.88e-5)"	"unprognostic (2.17e-1)"	"unprognostic (1.30e-1)"	"unprognostic (2.60e-2)"	"unprognostic (5.09e-1)"	"unprognostic (4.98e-1)"	"unprognostic (1.32e-2)"	4.4	1.9	3.8	1.7	4.2	0.8	3.0	3.9	4.6	3.0	2.7	2.2	2.1	2.1	0.7	6.0	3.2	0.5	2.1	3.8	3.5	2.4	2.0	1.5	1.0	4.8	3.5	6.8	3.0	0.6	2.4	82.3	4.4	2.6	0.1	0.6	3.7	0.5	4.4	6.3	2.1	0.2	3.2	2.0	2.2	3.8	3.9	0.4	2.8	0.0	0.4	1.7	3.1	6.1	7.0	6.0	1.8	20.2	1.0	0.3	399.0	4.3	0.0	0.0	0.0	2.9	2.8	0.1	4.0	0.2	1.8	9.7	0.7	3.9	0.0	7.6	10.7	3.7	3.8	4.3	0.9	2.7	3.9	0.9	13.2	0.5	2.7	1.5	0.1	2.6	5.7	1.2	0.0	4.8	3.2	2.3	0.4	1.4	2.8	3.9	3.0	2.5	0.5	3.4	4.3	5.6	2.4	41.4	4.2	0.9	48.5	1.1	4.3	2.7	5.4	2.4	2.7	7.7	4.6	1.5	1.9	1.9	2.8	1.0	2.2	2.5	1.1	2.4	1.3	1.2	1.4	1.1	1.3	1.4	1.0	1.0	2.2	1.6	1.5	0.9	0.8	2.0	3.8	4.2	3.9	4.6	3.8	3.5	4.8	3.5	4.4	3.2	3.9	6.1	2.3	0.0	2.2	6.5	2.2	3.1	8.0	14.9	6.2	8.3	11.6	10.7	3.0	4.3	5.3	5.5	12.5	333.0	3.3	4.7	23.5	1.7	1.4	3.3	9.3	4.2	4.2	0.8	1.4	5.6	30.4	11.6	1.5	3.8	2.5	1574.2	3.6	6.4	29.7	10.1	1.6	2.7	8.2	0.6	1.2	1.9	1.8	3.6	1.8	1.9	1.0	11.2	2.1	2.0	3.3	2.0	2.0	3.4	1.4	11.6	2.5	20.5	4.2	8.9	0.0	6.7	29.2	0.8	2.7	14.6	7.4	1495.8	2.6	30.0	2.6	10.4
HSD17B11	"17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2"	ENSG00000198189	"Hydroxysteroid 17-beta dehydrogenase 11"	Q8NBQ5	4	87336515-87391188	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 288.6;liver: 241.6"	"Cell type enhanced"	"Detected in all"		"Paneth cells: 498.6;Proximal enterocytes: 1134.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 768.7"	"Group enriched"	"Detected in all"	4	"granulocytes: 768.7;monocytes: 202.0"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 295.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA021608	Enhanced		Supported	"Lipid droplets"	"Intracellular and membrane"	NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 45: Enterocytes - Digestion"	"Lipid droplets"		"HPA021608: AB_1847660"	"unprognostic (4.53e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.35e-2)"	"unprognostic (4.14e-2)"	"unprognostic (9.68e-2)"	"unprognostic (1.92e-1)"	"unprognostic (3.35e-1)"	"unprognostic (3.70e-2)"	"unprognostic (1.78e-1)"	"unprognostic (8.53e-2)"	"unprognostic (1.24e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.65e-3)"	"unprognostic (5.53e-2)"	"unprognostic (2.13e-2)"	"unprognostic (2.44e-2)"	"unprognostic (1.04e-2)"	56.0	64.1	15.0	33.0	15.7	109.9	45.5	19.7	18.6	44.0	18.8	139.6	216.7	57.5	28.2	21.5	44.2	107.7	21.0	15.6	18.4	75.9	241.6	104.4	41.5	20.1	17.5	60.6	54.5	10.9	13.1	47.2	18.9	25.5	145.8	8.2	14.8	34.2	12.1	14.5	288.6	49.4	19.3	42.7	36.6	10.1	16.7	36.3	19.3	26.3	34.9	41.8	33.5	22.8	1.0	45.4	22.2	56.1	66.5	92.4	31.2	23.4	39.3	16.1	29.9	38.2	295.2	0.0	45.8	26.2	14.8	0.9	65.6	5.2	18.0	72.1	13.8	63.3	22.9	131.0	37.6	114.8	114.0	65.3	1.7	22.5	7.4	51.3	31.5	27.4	67.9	32.7	30.1	1.8	24.0	144.8	37.8	146.7	7.6	63.2	20.4	77.7	45.5	70.0	7.2	69.3	47.5	1.6	87.0	28.2	0.1	112.7	24.9	11.0	47.9	43.1	13.0	15.0	6.6	7.1	20.1	80.6	77.0	591.1	202.0	442.9	62.5	142.7	74.8	57.1	62.6	64.6	108.2	47.6	55.8	64.2	768.7	82.3	125.8	36.8	77.4	171.6	15.0	15.7	19.7	18.6	15.6	18.4	20.1	17.5	18.9	19.3	16.7	22.8	169.0	314.1	179.5	13.4	89.0	28.0	77.0	16.0	10.8	1.8	5.0	6.2	5.3	368.9	83.7	44.1	2.1	30.6	63.1	356.8	25.4	53.9	1.2	9.0	28.1	101.8	93.7	68.8	16.8	58.6	59.7	77.3	28.1	18.8	100.1	34.1	112.5	337.3	129.1	18.5	14.7	180.8	18.3	220.4	176.2	5.1	104.1	139.1	67.6	43.1	197.3	36.3	113.3	16.6	19.0	65.9	498.6	59.5	60.8	39.5	1134.9	173.6	62.2	3.9	72.3	77.9	43.0	2.7	15.4	10.4	21.5	14.9	93.8	65.4	281.0	93.9
HSD17B12	"KAR, SDR12C1"	ENSG00000149084	"Hydroxysteroid 17-beta dehydrogenase 12"	Q53GQ0	11	43680680-43856617	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA016427	Approved					NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA016427: AB_1844347"	"unprognostic (1.93e-1)"	"unprognostic (1.92e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.62e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.14e-3)"	"prognostic unfavorable (2.76e-4)"	"unprognostic (2.99e-1)"	"unprognostic (3.31e-2)"	"unprognostic (9.16e-3)"	"unprognostic (5.16e-2)"	"unprognostic (7.54e-2)"	"prognostic favorable (2.10e-8)"	"unprognostic (6.87e-2)"	"unprognostic (1.49e-1)"	"unprognostic (2.43e-1)"	"unprognostic (2.28e-2)"	60.9	65.4	42.0	31.4	50.4	25.1	48.8	58.1	63.0	51.3	71.5	65.8	67.3	37.4	50.6	36.3	41.3	35.6	69.5	42.0	54.3	91.3	122.9	51.4	28.5	58.8	52.1	45.3	43.5	134.3	28.5	41.6	58.9	52.8	59.5	47.0	46.9	41.5	27.8	30.0	41.7	48.6	52.8	34.8	56.1	33.5	48.9	22.3	66.8	51.6	32.3	31.4	26.8	61.9	40.2	64.3	68.4	69.6	226.8	211.5	45.0	96.7	97.8	67.3	73.0	75.7	80.7	97.4	69.4	91.5	111.7	151.6	48.7	125.5	82.6	19.0	89.2	46.4	28.3	66.2	114.6	132.3	125.4	131.1	93.6	68.1	193.6	85.9	96.1	60.4	43.9	157.9	59.4	22.9	38.6	63.1	126.0	49.9	45.3	63.9	102.3	110.8	129.5	95.9	24.5	56.5	132.0	110.7	100.2	64.6	80.2	112.5	92.4	73.9	28.3	189.3	117.6	81.6	110.3	58.3	78.5	25.0	55.4	8.8	13.4	7.0	12.1	14.8	13.5	12.7	9.6	10.5	21.3	15.2	15.6	13.9	11.2	16.4	8.2	18.4	6.2	11.6	42.0	50.4	58.1	63.0	42.0	54.3	58.8	52.1	58.9	52.8	48.9	61.9	73.6	64.1	111.1	96.6	45.4	31.7	47.1	92.8	57.5	77.1	46.1	36.4	80.7	74.4	81.4	51.5	77.2	60.4	30.6	82.2	27.4	100.2	61.8	36.9	47.5	70.9	138.2	40.8	126.9	82.3	42.1	59.7	60.6	37.0	155.9	37.3	76.1	214.0	63.5	121.1	155.6	75.5	87.5	50.9	43.7	24.1	34.2	45.3	39.2	59.0	37.2	128.2	30.9	128.7	97.5	71.4	62.5	56.8	61.4	61.3	54.2	50.1	75.8	67.8	78.9	45.4	60.2	17.5	14.5	66.0	45.7	74.8	29.4	95.5	115.5	48.6
HSD17B2	"HSD17, SDR9C2"	ENSG00000086696	"Hydroxysteroid 17-beta dehydrogenase 2"	P37059	16	82035004-82098534	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"intestine: 429.0;liver: 217.9;placenta: 381.8"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 155.8;Distal enterocytes: 203.4;Hepatocytes: 121.9;Paneth cells: 284.2;Proximal enterocytes: 390.7"	"Group enriched"	"Detected in many"	4	"liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 57.9;Hep G2: 47.5;hTERT-HME1: 27.1;OE19: 87.1;RT4: 96.8;TIME: 54.0"	"Group enriched"	"Detected in some"	5	"midbrain: 2.2;pons and medulla: 3.4"	"Not detected"	"Not detected"			"HPA021826, HPA050235"	Enhanced		Approved	"Endoplasmic reticulum"		NA	NA				"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 21: OE19 - Mitochondria"	"Cluster 45: Enterocytes - Digestion"	"Endoplasmic reticulum"		"HPA021826: AB_10961148, HPA050235: AB_2681059"	"unprognostic (1.50e-1)"	"unprognostic (2.53e-2)"	"unprognostic (1.42e-1)"	"unprognostic (6.48e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.77e-1)"	"unprognostic (4.29e-2)"	"unprognostic (2.60e-1)"	"unprognostic (7.35e-2)"	"unprognostic (6.05e-3)"	"unprognostic (4.98e-2)"	"unprognostic (7.35e-2)"	"unprognostic (6.31e-4)"	"unprognostic (5.39e-2)"	"unprognostic (1.14e-1)"	"unprognostic (4.30e-2)"	"prognostic favorable (3.83e-4)"	1.6	0.0	0.4	4.2	0.2	0.7	26.4	0.9	0.4	4.3	0.2	74.8	429.0	1.2	0.1	9.6	0.1	21.1	0.2	0.3	0.2	9.6	217.9	2.3	0.3	0.1	0.0	0.3	23.2	0.0	1.2	381.8	0.1	2.0	56.9	17.4	22.1	0.2	0.1	4.2	188.6	2.4	0.0	0.2	20.1	0.3	0.1	0.4	0.1	0.0	3.4	78.6	1.4	0.3	0.4	0.1	0.4	0.0	0.0	0.7	0.7	0.2	57.9	0.0	0.0	10.9	1.7	0.1	11.4	0.0	0.1	0.4	0.0	2.4	0.0	0.1	0.1	0.3	0.3	47.5	0.4	0.3	0.3	0.0	3.1	0.0	27.1	0.6	0.9	0.1	0.1	0.4	8.6	0.1	0.0	0.9	0.2	87.1	21.4	0.1	0.2	1.3	1.0	96.8	0.4	1.5	0.0	2.7	0.2	0.0	0.1	0.1	54.0	0.6	0.5	0.3	0.0	0.2	0.2	0.3	0.0	0.2	0.0	0.3	0.1	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.5	0.1	0.1	0.2	0.0	0.0	0.4	0.2	0.9	0.4	0.3	0.2	0.1	0.0	0.1	0.0	0.1	0.3	1.0	3.2	3.9	0.3	0.7	0.4	2.7	16.4	2.2	0.5	45.7	12.3	0.6	155.8	21.4	0.0	0.0	2.7	0.3	203.4	0.0	73.6	0.5	5.9	5.4	21.3	3.0	2.7	0.1	6.0	1.8	38.3	15.3	41.3	0.0	0.0	2.5	121.9	3.5	0.0	0.1	26.3	6.1	3.1	0.0	0.9	0.0	0.4	1.8	0.0	0.0	45.1	0.0	0.0	0.1	20.1	284.2	0.0	0.1	2.7	390.7	1.4	5.6	0.7	0.0	0.4	2.0	0.0	0.1	0.8	1.1	6.4	0.7	0.0	47.1	14.8
HSD17B3	SDR12C2	ENSG00000130948	"Hydroxysteroid 17-beta dehydrogenase 3"	P37058	9	96235306-96302176	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase	"Disease variant, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 15.1;testis: 36.7"	"Group enriched"	"Detected in some"	6	"Leydig cells: 108.1;Oligodendrocytes: 93.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HBEC3-KT: 2.3;HEL: 1.0;U-2 OS: 4.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA056833	Enhanced		Approved	Vesicles		NA	NA				"Cluster 78: Testis - Spermatogenesis"	"Cluster 9: U-2 OS - Unknown function"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Vesicles		"HPA056833: AB_2683252"	"unprognostic (2.78e-1)"	"unprognostic (6.61e-3)"	"unprognostic (1.03e-1)"	"unprognostic (5.76e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.55e-1)"	"unprognostic (3.08e-2)"	"unprognostic (6.15e-2)"	"unprognostic (1.74e-1)"	"unprognostic (5.13e-2)"	"unprognostic (3.26e-4)"	"unprognostic (3.45e-1)"	"unprognostic (5.48e-8)"	"unprognostic (8.47e-3)"	"unprognostic (1.15e-1)"	"unprognostic (7.24e-2)"	"unprognostic (3.11e-2)"	1.6	0.8	3.1	0.2	4.3	0.0	1.7	3.4	5.9	3.1	2.4	2.7	0.5	1.5	0.9	0.7	3.5	0.2	2.1	3.1	3.6	4.7	15.1	1.8	0.0	4.3	3.9	1.4	4.2	0.0	1.7	0.1	4.2	3.2	0.1	0.7	1.0	0.1	0.5	0.9	3.7	0.0	3.3	0.9	1.4	36.7	4.2	0.1	10.0	0.1	0.0	1.6	1.8	5.4	0.0	0.0	0.0	0.1	0.0	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	2.3	0.0	0.0	0.0	1.0	0.0	0.1	0.2	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.1	0.1	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	4.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	3.1	4.3	3.4	5.9	3.1	3.6	4.3	3.9	4.2	3.3	4.2	5.4	0.0	0.0	0.0	15.3	0.2	0.0	0.1	0.8	0.0	0.2	0.1	0.0	0.6	0.0	0.2	0.0	0.0	0.0	0.0	0.4	0.0	0.2	4.0	0.2	0.0	0.4	1.8	0.0	0.5	0.4	0.0	0.1	0.0	0.2	0.0	0.0	0.0	2.5	0.0	0.0	0.5	0.5	0.0	0.0	0.4	14.4	108.1	1.1	0.0	4.7	0.1	0.6	0.0	1.0	93.2	0.2	0.1	12.8	0.0	0.1	0.6	0.0	0.5	0.2	0.0	0.1	0.5	1.9	1.8	0.0	0.3	0.1	0.0	0.0	0.3	0.0
HSD17B6	"HSE, RODH, SDR9C6"	ENSG00000025423	"Hydroxysteroid 17-beta dehydrogenase 6"	O14756	12	56752161-56787790	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	26	"liver: 1804.3"	"Cell type enriched"	"Detected in many"	11	"Hepatocytes: 1969.3"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 170.3"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"Karpas-707: 13.4;U-266/84: 18.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA059141	Enhanced		Approved	Nucleoplasm,Vesicles		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 62: Liver - Hemostasis"	"Cluster 16: U-266 - Nucleosome"	"Cluster 2: Hepatocytes - Metabolism"	"Nucleoplasm, Vesicles"		"HPA059141: AB_2683922"	"unprognostic (7.70e-2)"	"unprognostic (8.76e-2)"	"unprognostic (5.08e-2)"	"unprognostic (1.92e-2)"	"unprognostic (2.01e-1)"	"unprognostic (3.79e-2)"	"prognostic favorable (6.32e-4)"	"unprognostic (1.06e-2)"	"unprognostic (3.21e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.35e-1)"	"unprognostic (6.74e-2)"	"unprognostic (2.50e-10)"	"unprognostic (1.26e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.05e-1)"	8.5	2.5	13.1	6.9	16.2	0.5	0.7	13.4	18.9	28.0	9.4	24.7	3.2	20.9	1.6	9.9	6.5	9.1	0.8	12.3	12.6	2.5	1804.3	63.2	0.8	12.0	14.6	6.0	0.6	0.5	0.6	5.4	11.5	51.2	7.6	0.8	0.4	69.2	0.4	1.2	4.8	13.1	12.4	47.5	5.7	23.3	13.7	0.9	31.4	0.5	0.9	36.7	14.6	12.8	0.3	0.8	1.9	0.4	1.9	1.4	2.3	4.1	3.5	1.9	1.9	0.4	0.4	12.0	1.7	0.5	0.5	0.3	6.1	1.1	1.1	7.7	2.2	3.7	1.2	0.6	1.2	1.9	6.0	1.0	0.4	1.2	0.6	0.6	0.0	10.3	1.1	13.4	0.9	2.4	5.6	1.3	7.5	0.7	0.7	7.4	0.8	2.9	0.2	1.4	11.0	2.3	2.0	3.6	0.9	0.7	0.6	1.5	0.3	0.9	0.8	4.0	1.0	11.7	18.0	7.8	1.3	6.9	0.6	0.0	0.0	0.0	1.0	0.2	1.2	0.7	0.8	0.8	0.2	0.3	1.1	0.7	0.0	0.0	0.5	0.7	1.0	0.3	13.1	16.2	13.4	18.9	12.3	12.6	12.0	14.6	11.5	12.4	13.7	12.8	0.4	173.1	130.6	21.2	6.1	1.3	3.1	0.6	0.6	0.4	0.7	0.6	0.2	27.1	9.3	0.0	0.0	1.4	0.4	0.0	0.0	0.1	4.6	0.7	3.5	1.3	0.0	29.5	1.4	0.0	2.6	5.0	0.0	0.1	0.0	1.6	26.0	1969.3	0.4	0.0	2.1	0.4	0.0	40.2	0.3	4.5	12.5	0.5	0.0	1.0	1.0	1.3	0.0	3.0	5.5	0.1	0.0	1.5	0.8	16.1	0.0	0.3	1.5	0.6	13.1	0.6	3.5	16.4	11.4	1.2	1.6	0.4	2.2	36.0	0.7	1.1
HSD17B7	"PRAP, SDR37C1"	ENSG00000132196	"Hydroxysteroid 17-beta dehydrogenase 7"	P56937	1	162790702-162812817	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 30.2"	"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047496	Approved					NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 85: Liver - Metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA047496: AB_2680068"	"unprognostic (2.93e-1)"	"unprognostic (1.36e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.34e-1)"	"unprognostic (1.63e-3)"	"unprognostic (2.57e-1)"	"unprognostic (2.51e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.38e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (8.47e-5)"	"unprognostic (6.25e-2)"	"unprognostic (1.90e-1)"	"unprognostic (6.35e-2)"	"unprognostic (3.17e-2)"	4.3	16.1	3.3	5.1	3.1	2.8	8.2	3.0	6.0	5.6	3.8	6.4	6.7	4.0	7.2	8.9	5.1	4.2	3.5	2.9	4.0	5.2	30.2	7.6	8.3	3.8	3.7	6.8	5.3	5.1	7.7	4.6	3.9	5.9	8.0	4.0	6.2	3.5	6.0	7.6	6.6	4.4	3.3	5.6	5.9	2.6	3.7	8.1	6.1	2.8	8.1	5.5	5.6	3.7	12.6	12.2	32.4	13.8	18.4	18.3	20.2	4.6	15.9	9.4	19.0	17.0	35.7	29.6	10.6	4.4	58.3	19.1	30.6	43.4	9.9	12.4	15.5	7.7	8.2	26.8	15.2	13.9	12.7	11.6	23.5	36.8	11.6	7.4	15.7	19.4	14.5	19.0	8.3	8.9	17.7	13.7	20.5	24.4	15.3	9.5	19.3	18.5	33.3	19.5	27.6	14.6	8.0	7.7	7.9	27.5	12.3	17.1	9.8	4.4	10.2	6.7	10.0	11.2	12.7	29.4	6.6	1.2	11.1	21.7	6.7	12.1	13.6	6.8	14.8	12.6	10.1	13.7	6.9	11.9	12.9	12.4	5.5	8.2	8.5	10.0	17.9	12.2	3.3	3.1	3.0	6.0	2.9	4.0	3.8	3.7	3.9	3.3	3.7	3.7	8.8	0.0	25.5	22.5	22.6	11.0	19.5	48.3	35.9	23.6	24.9	11.9	2.4	12.8	26.1	11.0	62.6	17.2	19.9	14.9	3.9	16.9	2.0	9.4	7.9	12.0	6.0	4.2	8.4	27.1	15.1	13.1	8.6	9.3	5.1	32.8	8.9	62.0	13.4	11.8	9.1	14.5	18.3	5.0	16.9	1.9	6.8	12.2	17.8	5.6	10.6	14.3	16.5	12.5	22.6	15.0	17.9	7.2	18.1	19.0	12.1	10.2	19.9	44.1	0.0	5.9	10.5	4.9	6.6	15.6	12.6	19.2	23.5	34.1	11.6	12.6
HSD17B8	"D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1"	ENSG00000204228	"Hydroxysteroid 17-beta dehydrogenase 8"	Q92506	6	33204655-33206831	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 125.2;Proximal tubular cells: 137.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042132	Enhanced					NA	NA		97000	"Cluster 35: T-regs - Unknown function"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"HPA042132: AB_10793978"	"prognostic favorable (9.99e-4)"	"unprognostic (4.24e-1)"	"unprognostic (2.43e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.10e-1)"	"unprognostic (8.11e-2)"	"prognostic favorable (1.90e-5)"	"unprognostic (1.50e-3)"	"unprognostic (3.12e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.89e-1)"	"prognostic favorable (2.18e-12)"	"unprognostic (2.82e-2)"	"unprognostic (5.57e-1)"	"unprognostic (3.09e-1)"	"unprognostic (3.23e-2)"	9.6	24.6	10.1	6.5	10.5	9.7	17.0	9.9	11.3	13.7	10.9	18.0	19.7	7.2	29.4	25.5	23.6	7.9	20.3	9.6	10.8	30.7	67.4	11.2	10.5	11.3	11.9	8.6	55.3	42.2	14.1	5.6	12.3	11.3	16.2	11.8	25.1	16.5	20.8	25.9	18.8	7.3	11.4	12.1	15.1	5.9	10.8	13.3	32.9	25.0	15.1	9.8	12.8	11.3	7.0	15.0	6.8	9.3	2.3	4.4	1.3	0.8	4.7	0.1	0.1	5.8	17.5	45.4	11.2	1.2	2.2	29.1	7.2	11.7	1.0	8.6	0.0	2.6	14.0	27.1	20.0	0.0	3.8	5.0	28.9	0.2	49.4	0.4	2.1	13.6	0.3	46.2	4.1	9.4	31.2	1.3	2.1	23.3	2.9	11.0	1.2	79.5	27.8	1.3	12.1	7.6	2.9	34.3	7.6	4.6	62.0	1.8	1.3	0.7	7.3	0.6	0.4	65.5	42.4	16.6	3.1	1.0	1.7	0.1	5.8	2.0	18.7	13.4	30.0	16.6	24.0	29.2	11.6	13.1	26.4	28.5	0.7	16.8	14.6	20.8	21.8	26.7	10.1	10.5	9.9	11.3	9.6	10.8	11.3	11.9	12.3	11.4	10.8	11.3	12.5	19.2	21.6	3.3	18.6	29.7	28.3	55.0	21.6	12.4	31.3	34.8	31.8	48.6	25.9	22.0	6.2	29.9	9.7	21.2	125.2	27.9	6.3	20.0	6.0	10.1	18.0	12.8	0.3	32.4	12.9	9.1	16.3	13.7	7.0	9.8	10.0	83.2	17.4	1.7	0.5	26.6	20.3	10.3	16.4	18.1	7.5	7.9	49.8	1.0	8.1	32.6	6.2	1.0	0.7	21.9	21.1	6.0	47.6	15.4	74.8	137.2	33.3	14.8	0.0	11.3	9.8	8.1	8.5	40.0	37.2	17.4	18.0	29.8	44.4	31.5
HSD3B1	"HSD3B, HSDB3, SDR11E1"	ENSG00000203857	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1"	P14060	1	119507198-119515054	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism, Steroidogenesis"	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	9	"placenta: 77.7"	"Group enriched"	"Detected in some"	8	"Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0"	"Cancer enriched"	"Detected in single"	4	"urothelial cancer: 1.6"	"Region enhanced"	"Detected in some"		"basal ganglia: 1.0;cerebral cortex: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	6	"CACO-2: 64.1;SuSa: 26.5"									"HPA043261, HPA043264, HPA044028"	Supported		Approved	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 28: Placenta - Pregnancy"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"			"unprognostic (1.53e-1)"				"unprognostic (7.11e-2)"					"unprognostic (1.15e-1)"		"unprognostic (1.04e-1)"			"prognostic favorable (4.59e-5)"	0.1	1.2	0.2	0.0	1.0	0.0	1.5	0.0	1.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	77.7	0.0	0.1	0.5	0.0	0.1	0.0	0.1	4.5	8.7	0.5	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.7	0.2	0.0	0.0	0.0	64.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.8	0.0	0.0	0.0	0.0	0.0	3.9	0.0	0.0	7.0	0.7	0.8	26.5	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	1.0	0.0	1.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	23.6	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	0.0	140.8	0.8	0.0	0.0	0.0	0.0	0.0	0.0	7.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.0	37.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	502.0	0.0	0.1	1.0	0.0
HSD3B2	SDR11E2	ENSG00000203859	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2"	P26439	1	119414931-119423035	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	Steroidogenesis	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	56	"adrenal gland: 2174.8"	"Group enriched"	"Detected in some"	4	"Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9"	"Cancer enhanced"	"Detected in single"		"testis cancer: 0.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"SK-MEL-30: 1.4"									"HPA043261, HPA043264, HPA044028"	Supported		Uncertain	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 52: Non-specific - Transcription"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"	"unprognostic (3.56e-1)"		"unprognostic (1.85e-1)"		"unprognostic (2.80e-1)"		"unprognostic (2.72e-2)"		"unprognostic (8.87e-2)"	"unprognostic (3.91e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.94e-1)"	"unprognostic (6.51e-2)"	"unprognostic (1.97e-2)"	"unprognostic (1.55e-1)"			0.2	2174.8	0.3	2.1	0.8	0.0	0.1	0.0	0.7	0.2	0.0	7.7	0.0	0.2	0.0	0.2	0.4	0.0	0.3	0.2	0.0	0.9	1.0	0.5	0.0	0.0	0.0	0.9	0.5	0.0	0.1	3.6	0.1	0.4	1.0	0.0	1.0	0.0	0.1	0.2	38.7	0.1	0.0	0.2	0.3	2.9	0.2	0.5	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.4	0.0	0.0	1.4	0.5	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.8	0.0	0.7	0.2	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	11.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.1	3.5	0.0	0.0	0.0	40.6	0.0	0.0	0.1	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	2.6	0.0	0.0	38.8	0.4	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	68.9	1.7	0.0
SRD5A1		ENSG00000145545	"Steroid 5 alpha-reductase 1"	P18405	5	6633427-6674386	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins"	"Differentiation, Sexual differentiation"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 29.0"	"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 3.5"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA051402	Approved					NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 20: HeLa - Mitochondria"	"Cluster 61: Squamous epithelial cells - Keratinization"			"HPA051402: AB_2681470"	"unprognostic (1.40e-2)"	"unprognostic (1.33e-2)"	"unprognostic (2.30e-3)"	"prognostic unfavorable (8.73e-6)"	"unprognostic (9.38e-3)"	"unprognostic (8.90e-2)"	"unprognostic (3.78e-2)"	"unprognostic (5.90e-2)"	"unprognostic (3.83e-1)"	"unprognostic (1.42e-1)"	"unprognostic (7.70e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.56e-3)"	"unprognostic (3.01e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.59e-1)"	"unprognostic (5.47e-2)"	1.5	2.0	4.7	1.9	5.3	2.2	11.0	7.4	8.8	3.9	0.1	2.4	4.1	1.7	3.0	11.0	1.7	1.7	1.0	5.5	3.2	4.6	29.0	1.9	2.3	6.0	3.3	2.5	2.3	1.4	1.1	1.0	6.3	1.5	2.3	3.8	2.7	1.1	1.3	13.6	4.1	1.6	1.8	1.4	2.5	1.5	6.9	1.6	1.3	0.7	4.1	1.1	6.6	8.3	5.2	6.1	8.0	6.7	7.6	7.3	3.5	5.7	4.5	5.7	3.5	6.0	5.3	7.1	8.1	8.7	9.1	9.8	6.6	4.0	6.0	4.3	2.6	2.2	15.3	3.7	3.4	3.3	1.8	5.4	11.3	4.1	3.2	4.2	2.9	2.7	3.7	6.2	7.5	7.1	1.4	3.6	4.5	4.1	4.7	5.1	5.8	2.0	7.6	5.4	14.0	6.4	18.2	7.6	5.8	6.1	2.6	0.9	5.8	8.6	3.4	14.2	7.6	2.3	3.6	2.6	7.2	3.6	8.0	3.5	1.3	0.5	0.3	1.0	0.2	0.5	0.3	0.5	1.6	0.6	0.2	0.3	0.7	0.5	1.1	0.7	0.4	0.5	4.7	5.3	7.4	8.8	5.5	3.2	6.0	3.3	6.3	1.8	6.9	8.3	3.7	3.2	2.7	7.8	11.9	18.5	6.7	19.0	67.2	5.0	14.5	9.1	2.6	11.5	12.8	5.5	4.2	0.9	5.0	8.3	7.9	9.8	8.1	2.6	4.3	3.2	2.4	4.4	15.5	4.7	7.4	4.7	16.3	3.2	1.3	6.0	4.6	103.4	13.0	6.7	14.9	7.2	52.9	19.4	11.6	2.6	3.4	11.6	7.2	6.5	50.7	5.1	10.3	9.0	7.6	6.7	10.4	7.9	7.2	9.4	24.9	23.4	10.4	3.8	0.0	3.7	6.1	3.4	4.4	139.2	30.4	0.8	5.9	5.2	12.0	10.2
SRD5A2		ENSG00000277893	"Steroid 5 alpha-reductase 2"	P31213	2	31522480-31580938	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters"	"Differentiation, Sexual differentiation"	Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	15	"epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0"	"Group enriched"	"Detected in some"	5	"Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9"	"Group enriched"	"Detected in some"	6	"endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2"	"Region enriched"	"Detected in single"	11	"midbrain: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"RT4: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 34: Spermatids - Unknown function"				"unprognostic (6.75e-3)"	"unprognostic (2.00e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.08e-3)"	"unprognostic (5.92e-3)"	"unprognostic (3.37e-2)"	"unprognostic (2.79e-3)"	"unprognostic (6.56e-2)"	"unprognostic (9.10e-2)"	"unprognostic (1.39e-2)"	"unprognostic (3.06e-2)"	"unprognostic (9.79e-3)"	"unprognostic (6.61e-6)"	"unprognostic (4.37e-2)"	"unprognostic (2.04e-1)"	"unprognostic (3.85e-1)"	"unprognostic (3.48e-3)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.2	23.5	0.0	20.4	0.0	0.0	0.0	0.0	0.3	60.8	0.7	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	16.8	0.0	0.1	0.0	18.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	1.4	0.0	0.2	0.0	0.0	0.0	1.6	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.1	0.0	6.2	0.0	0.0	0.0	0.0	0.0	0.6	2.8	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	71.7	29.6	0.2	0.2	0.0	0.0	0.9	0.0	0.0	1.9	0.0	0.5	0.0	0.0	0.4	20.0	0.0	0.0	1.0	0.0	0.0	0.3	0.0	59.9	0.6	0.1	0.0	3.7	0.0	0.0	0.0	0.5	0.9	0.1	0.0	1.2	0.0	0.7	0.0	0.3	7.3	0.0	0.0	0.0	0.2	1.2	0.8	0.0	0.0	0.0	0.1	0.0	0.0	8.6
SRD5A3	"FLJ13352, SRD5A2L, SRD5A2L1"	ENSG00000128039	"Steroid 5 alpha-reductase 3"	Q9H8P0	4	55346213-55373100	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		Oxidoreductase	"Cataract, Congenital disorder of glycosylation, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 79.6"					"Low region specificity"	"Detected in all"			HPA027006	Uncertain		Approved	"Plasma membrane,Cytosol"		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Plasma membrane, Cytosol"		"HPA027006: AB_1857469"	"unprognostic (1.12e-2)"	"unprognostic (1.01e-1)"	"unprognostic (4.02e-2)"	"prognostic favorable (9.39e-4)"	"unprognostic (1.50e-2)"	"unprognostic (4.81e-2)"	"prognostic unfavorable (1.80e-6)"	"unprognostic (9.31e-2)"	"unprognostic (5.28e-2)"	"unprognostic (1.81e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (4.85e-10)"	"unprognostic (4.16e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.43e-2)"	"unprognostic (9.52e-2)"	12.5	12.0	10.4	2.5	11.5	3.7	12.2	11.0	12.4	12.9	9.2	7.3	3.8	6.8	4.2	26.1	5.6	10.3	9.3	10.7	10.1	9.6	14.5	10.5	2.5	11.0	11.2	3.1	20.2	7.0	5.9	4.0	10.8	7.4	4.1	1.5	16.4	2.9	6.3	15.4	7.0	2.6	10.9	6.8	9.7	3.3	10.9	6.0	7.6	5.4	6.0	10.0	14.7	12.7	9.7	4.3	10.3	10.1	29.4	20.4	5.6	10.4	9.3	2.4	5.4	6.5	19.5	21.2	11.7	11.0	11.1	7.0	5.3	7.9	3.9	6.6	17.1	12.3	5.2	15.8	9.2	23.7	6.1	17.6	14.5	5.4	5.3	7.8	14.4	38.5	21.2	47.7	21.1	10.8	36.0	10.3	13.0	53.2	9.3	11.4	3.3	14.0	12.8	7.9	16.0	9.1	10.7	79.6	8.3	9.0	9.4	17.9	8.3	25.0	4.7	2.0	8.1	28.6	15.8	7.9	34.1	29.5	25.9	25.6	35.8	11.7	16.1	56.5	18.6	12.5	12.0	15.2	30.2	12.7	10.2	14.4	1.8	8.6	59.5	61.7	12.5	23.1	10.4	11.5	11.0	12.4	10.7	10.1	11.0	11.2	10.8	10.9	10.9	12.7	25.4	9.6	15.9	4.6	7.8	13.6	13.3	245.5	5.2	4.9	43.8	29.3	5.3	34.3	245.2	5.5	4.2	27.0	21.2	12.2	3.9	93.4	3.2	51.2	31.0	19.6	12.0	14.9	11.1	105.4	106.0	16.2	13.3	105.9	14.0	6.7	17.5	18.6	63.4	10.1	17.1	22.6	57.0	32.4	34.1	0.5	1.8	27.6	24.9	4.7	31.3	21.9	18.6	8.5	23.4	155.5	10.0	5.7	16.8	17.5	9.4	18.4	195.0	3.9	13.1	13.3	28.2	3.5	20.1	32.7	29.7	7.5	7.2	15.4	23.3	108.6
STS	"ARSC, ARSC1"	ENSG00000101846	"Steroid sulfatase"	P08842	X	7147237-7804358	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Lipid metabolism, Pregnancy, Steroid metabolism"	Hydrolase	"Disease variant, Ichthyosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"placenta: 26.6"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 41.8;Excitatory neurons: 32.2;Inhibitory neurons: 39.3;Syncytiotrophoblasts: 94.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"ASC diff: 48.5;RPMI-8226: 69.8;U-266/70: 110.2;U-698: 47.2"					"Low region specificity"	"Detected in all"			HPA002904	Enhanced					NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"			"HPA002904: AB_1080116"	"unprognostic (1.09e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.44e-2)"	"unprognostic (2.75e-1)"	"unprognostic (6.72e-2)"	"unprognostic (1.94e-2)"	"unprognostic (2.62e-1)"	"unprognostic (1.84e-1)"	"unprognostic (8.23e-2)"	"unprognostic (4.67e-2)"	"prognostic unfavorable (3.47e-4)"	"unprognostic (4.05e-2)"	"unprognostic (2.78e-2)"	"unprognostic (2.77e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.92e-2)"	"unprognostic (1.34e-1)"	18.2	4.6	3.7	4.5	4.8	2.1	5.8	4.0	12.1	5.6	1.3	6.8	2.8	4.3	2.4	3.1	4.8	7.3	6.6	4.2	3.7	4.8	8.7	8.7	4.1	5.8	6.1	4.7	3.0	2.8	1.2	26.6	5.5	5.2	5.9	6.1	3.1	5.6	5.2	4.9	3.2	6.8	1.3	4.7	12.0	2.4	12.1	4.4	3.9	6.6	3.6	9.4	3.9	7.8	11.5	3.7	7.5	3.0	48.5	24.9	37.5	22.3	7.8	5.8	5.3	19.2	11.2	21.4	5.0	15.5	5.0	3.0	5.4	3.9	5.8	3.3	8.6	1.8	12.7	5.7	2.7	3.8	11.5	8.3	0.7	3.8	2.3	4.0	8.8	2.0	1.4	23.5	15.2	2.9	2.2	3.1	3.3	0.2	4.8	3.9	4.8	69.8	14.2	16.0	5.6	4.8	4.7	8.3	3.0	11.8	3.8	1.6	15.8	22.5	2.2	30.0	4.4	110.2	0.8	47.2	5.9	3.0	6.5	0.9	1.7	0.4	0.4	2.0	0.2	0.4	0.2	0.2	0.9	0.7	0.1	0.3	1.3	0.7	1.3	0.3	0.3	0.6	3.7	4.8	4.0	12.1	4.2	3.7	5.8	6.1	5.5	1.3	12.1	7.8	10.2	12.8	2.2	10.4	1.8	0.9	1.8	2.9	0.6	3.5	3.3	1.5	7.5	1.5	8.5	1.8	0.0	41.8	1.6	16.7	0.0	8.6	0.3	4.5	4.5	4.2	3.6	3.2	32.2	19.9	18.9	6.1	5.1	5.2	7.0	6.7	3.6	8.2	7.7	1.7	39.3	4.6	10.2	7.5	1.7	0.4	2.8	2.8	1.8	10.3	4.7	2.6	0.0	19.1	12.1	10.2	6.5	6.8	1.9	7.8	4.6	3.0	7.5	0.8	0.0	17.5	5.7	0.5	1.7	0.4	1.0	94.0	1.0	4.0	4.3	8.9
SULT1E1	"EST, STE"	ENSG00000109193	"Sulfotransferase family 1E member 1"	P49888	4	69841212-69860145	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 27.5;liver: 37.2;skin 1: 19.3;vagina: 30.4"	"Cell type enhanced"	"Detected in some"		"Endometrial ciliated cells: 65.8;Glandular and luminal cells: 35.1;Hepatocytes: 51.4;Paneth cells: 66.3;Proximal enterocytes: 21.5"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	16	"HHSteC: 71.1;HSkMC: 32.3;hTCEpi: 27.3;HUVEC TERT2: 20.4"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in some"		"cerebral cortex: 7.8"	"HPA028213, HPA028728, CAB047344"	Enhanced		Uncertain	"Nuclear membrane,Cytosol"		NA	NA				"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 44: Endometrium - Transcription"	"Nuclear membrane, Cytosol"		"CAB047344: , HPA028213: AB_10599848, HPA028728: AB_10601894"	"unprognostic (5.60e-2)"	"prognostic favorable (4.06e-4)"	"unprognostic (2.48e-1)"	"unprognostic (1.07e-3)"	"unprognostic (2.42e-1)"	"unprognostic (1.95e-1)"	"unprognostic (1.70e-1)"	"unprognostic (1.72e-1)"	"unprognostic (1.41e-1)"	"unprognostic (2.89e-1)"	"unprognostic (3.22e-3)"	"unprognostic (8.62e-2)"	"unprognostic (6.48e-5)"	"unprognostic (2.48e-1)"	"unprognostic (4.11e-2)"		"unprognostic (5.55e-2)"	0.1	14.5	0.1	0.0	0.1	0.1	0.1	0.1	0.2	13.5	4.1	0.2	27.5	0.3	1.0	0.8	0.2	0.2	0.0	0.1	0.0	0.3	37.2	2.3	0.0	0.1	0.1	0.0	0.2	0.0	0.6	0.1	0.1	0.7	0.1	0.0	6.6	0.4	0.0	19.3	27.3	0.1	0.0	0.0	2.1	0.1	0.1	0.5	0.0	0.0	1.5	0.7	30.4	0.2	0.0	0.0	0.0	0.0	0.6	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	71.1	0.0	0.0	32.3	27.3	0.0	0.9	0.0	20.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.2	0.1	0.0	0.1	0.1	0.1	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	11.9	1.0	8.7	0.0	0.0	0.1	0.0	0.1	1.5	2.8	1.8	0.0	0.2	0.0	0.2	0.0	0.0	0.0	65.8	1.3	0.3	0.0	0.0	0.1	1.3	0.1	0.2	0.0	35.1	0.0	0.0	2.5	51.4	0.3	0.0	0.0	4.7	0.0	0.8	0.7	0.0	0.3	0.2	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.6	66.3	0.0	0.0	0.0	21.5	0.0	0.3	0.0	0.0	0.0	0.5	0.0	0.1	0.0	3.4	1.5	0.1	0.0	13.8	0.2
SULT2B1	HSST2	ENSG00000088002	"Sulfotransferase family 2B member 1"	O00204	19	48552172-48599425	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Transferase	"Disease variant, Ichthyosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 286.0;skin 1: 186.5;vagina: 145.9"	"Cell type enhanced"	"Detected in many"		"Prostatic glandular cells: 62.3;Proximal enterocytes: 75.9;Squamous epithelial cells: 56.0;Suprabasal keratinocytes: 137.4;Urothelial cells: 114.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	4	"CAPAN-2: 74.2;MCF7: 46.8;OE19: 122.9;T-47d: 36.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA041724, HPA043539, HPA076510"	Enhanced		Enhanced	Vesicles,Cytosol		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 22: Epithelial cell types - Mixed function"	Vesicles	Cytosol	"HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: "	"unprognostic (6.55e-2)"	"unprognostic (1.47e-1)"	"unprognostic (5.28e-3)"	"unprognostic (8.74e-2)"	"unprognostic (5.00e-2)"	"unprognostic (5.97e-2)"	"unprognostic (4.43e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.62e-1)"	"unprognostic (1.11e-2)"	"unprognostic (2.54e-2)"	"unprognostic (4.42e-2)"	"unprognostic (5.01e-6)"	"unprognostic (7.96e-3)"	"unprognostic (1.32e-1)"	"unprognostic (8.04e-2)"	"unprognostic (2.77e-2)"	0.3	0.2	0.5	0.4	0.4	0.1	11.5	0.6	0.8	74.4	0.4	0.8	9.3	0.5	6.8	286.0	1.2	2.7	0.2	0.5	0.5	13.0	0.3	9.4	0.0	0.5	0.7	0.1	0.7	7.9	0.4	1.5	0.5	22.6	0.2	0.0	53.6	3.7	0.4	186.5	18.2	0.1	0.4	0.1	3.5	0.5	0.9	0.4	1.9	0.0	28.3	0.7	145.9	0.5	12.6	15.8	0.0	0.3	0.0	0.0	0.4	0.0	0.1	0.0	0.1	0.9	74.2	0.1	0.1	0.0	0.7	3.9	0.1	0.3	0.0	0.5	0.4	0.0	0.5	0.5	0.0	0.0	7.2	0.2	2.1	0.0	0.0	0.1	0.0	0.8	0.1	0.1	0.0	46.8	0.0	0.5	0.0	122.9	0.0	0.1	0.0	0.1	0.0	3.5	0.2	0.1	0.0	6.2	0.3	0.0	36.7	0.1	0.2	0.0	0.3	0.1	0.0	0.1	0.1	0.1	0.0	0.4	0.3	0.5	0.1	0.0	0.3	0.2	0.6	0.0	0.2	0.1	0.1	0.0	0.0	0.1	0.1	0.2	0.2	0.2	0.1	0.2	0.5	0.4	0.6	0.8	0.5	0.5	0.5	0.7	0.5	0.4	0.9	0.5	0.4	19.2	0.5	1.0	0.0	24.1	30.5	11.6	0.0	0.0	16.8	12.4	0.6	5.7	40.2	9.2	0.0	3.2	0.0	4.4	0.0	12.2	0.0	15.7	1.4	0.9	4.8	0.0	1.0	1.2	3.1	1.2	2.6	17.5	0.0	0.1	0.0	0.3	0.7	0.0	0.9	12.6	24.4	0.0	4.8	0.9	0.3	0.4	12.4	1.0	0.0	1.6	0.0	0.5	0.8	18.5	7.9	0.0	0.0	62.3	75.9	1.3	6.7	0.6	0.0	0.1	2.2	0.2	11.1	56.0	137.4	1.9	0.6	2.0	9.2	114.6
