Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 46.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Breast glandular cells: 4.4;Early spermatids: 3.3;Hepatocytes: 2.5;Late spermatids: 1.9;Spermatocytes: 4.0" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 67.1" "Not detected" "Not detected" NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" 0.1 0.0 0.2 0.0 0.3 0.1 46.4 0.4 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.2 0.0 1.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.4 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 16.0 0.1 0.0 67.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 3.3 0.2 0.0 0.0 0.0 0.0 0.4 4.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.3 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.0 0.4 0.5 0.0 0.3 0.2 0.1 0.0 0.1 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 19.5;Proximal enterocytes: 39.2;Syncytiotrophoblasts: 27.4" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 69.7;PC-3: 50.0;SK-BR-3: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" 14.6 33.3 3.1 5.4 3.9 4.7 12.5 3.4 3.8 7.5 2.2 14.7 10.6 33.2 1.7 3.7 9.3 3.4 11.9 2.9 3.4 7.0 13.3 7.6 3.9 4.4 3.6 5.4 11.9 2.1 10.0 4.7 4.8 9.9 1.8 0.5 6.2 5.6 20.5 4.4 17.4 4.8 3.1 13.8 7.2 19.0 5.5 4.3 6.0 4.6 1.7 11.9 6.1 4.2 13.2 4.0 2.6 11.2 7.4 3.2 34.3 6.3 6.8 4.2 7.4 2.6 7.1 3.5 69.7 8.6 11.3 1.7 1.6 1.4 0.5 11.8 2.1 10.3 42.1 34.1 9.8 6.4 22.4 6.2 1.7 4.8 0.4 4.4 6.7 4.7 6.0 12.4 5.9 4.7 4.5 6.1 3.3 3.2 50.0 7.8 6.2 5.7 3.2 1.4 2.8 11.5 16.4 49.2 26.4 3.0 3.7 10.8 7.9 5.5 7.4 14.3 7.0 12.2 5.7 8.4 6.9 21.7 7.8 0.4 3.2 2.5 0.8 3.0 4.0 1.0 1.0 1.2 2.7 0.7 1.1 0.8 1.7 0.7 2.8 1.7 0.3 2.5 3.1 3.9 3.4 3.8 2.9 3.4 4.4 3.6 4.8 3.1 5.5 4.2 5.0 0.0 1.1 3.6 3.8 3.2 1.6 1.6 0.6 2.2 2.7 2.8 2.4 2.8 2.2 3.7 2.1 12.2 4.8 9.5 0.0 3.8 0.7 2.0 3.5 3.4 6.0 3.6 0.5 6.9 19.5 4.5 3.6 4.0 0.0 6.9 5.7 6.8 12.6 8.4 0.9 5.0 2.0 15.9 8.4 2.7 4.1 12.3 1.8 0.0 5.9 2.4 0.0 0.0 1.2 5.0 2.1 5.7 2.4 0.8 39.2 2.8 1.2 0.7 6.6 2.3 2.8 3.8 4.8 0.8 1.3 27.4 4.0 7.8 5.5 1.4 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;kidney: 3.7;liver: 3.1;skeletal muscle: 4.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Excitatory neurons: 2.7;Hepatocytes: 3.4;Inhibitory neurons: 2.8;Proximal tubular cells: 5.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "T-47d: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA058258: AB_2683656" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-2)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" 1.7 0.6 0.8 0.1 1.3 0.0 0.1 5.0 2.5 0.0 2.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.8 1.2 0.0 3.7 3.1 0.1 0.1 0.6 0.3 0.5 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.2 0.0 4.0 0.0 0.1 0.0 0.4 0.2 0.0 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 1.8 0.1 0.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 5.0 2.5 1.2 0.0 0.6 0.3 1.0 0.4 0.5 0.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7" "Cell type enhanced" "Detected in many" "granulocytes: 137.2;Late spermatids: 160.8;Proximal enterocytes: 179.4;Proximal tubular cells: 253.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.2;plasmacytoid DC: 35.7" "Group enriched" "Detected in many" 5 "dendritic cells: 35.7;NK-cells: 40.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 11.3 20.4 72.8 18.7 72.8 14.7 9.9 56.2 108.2 17.8 16.7 32.7 55.1 18.2 5.5 35.0 11.0 8.2 17.3 75.1 107.2 47.8 22.0 17.9 22.4 96.1 88.5 11.2 9.0 3.8 65.1 10.4 128.7 12.9 21.4 24.5 11.9 6.9 5.2 27.1 56.1 23.5 46.9 20.7 19.2 38.1 83.9 28.3 6.1 4.7 19.4 18.0 23.5 68.4 117.6 100.0 96.6 104.6 21.7 35.6 36.4 98.6 50.6 142.7 85.1 347.7 37.0 142.4 70.6 80.4 110.3 113.0 156.9 263.2 53.2 126.0 136.7 75.2 74.4 124.9 88.7 88.8 59.9 32.1 49.6 118.2 139.2 38.1 81.2 174.8 62.3 29.8 76.8 136.6 187.0 94.0 48.5 116.9 228.2 219.9 110.6 95.6 80.9 44.2 52.6 149.1 88.9 134.5 317.9 47.3 47.9 41.2 133.0 129.1 75.4 129.6 158.9 24.9 110.6 202.1 81.8 153.7 80.3 0.0 0.3 0.2 7.3 1.2 1.8 2.1 5.8 6.2 5.4 0.7 2.0 3.9 0.7 40.2 0.9 35.7 8.2 5.3 72.8 72.8 56.2 108.2 75.1 107.2 96.1 88.5 128.7 46.9 83.9 68.4 3.4 6.4 16.4 9.4 4.9 31.7 16.5 24.2 12.5 46.8 4.1 7.5 9.8 8.6 14.9 9.2 10.4 20.9 14.4 45.4 15.6 22.7 95.5 4.0 6.1 19.1 4.8 26.5 38.6 7.2 29.7 11.5 19.9 7.6 137.2 13.2 8.6 16.8 30.1 47.1 38.9 110.2 36.7 4.8 85.9 160.8 3.7 13.4 39.2 5.6 15.7 12.8 8.2 22.6 21.0 23.2 41.8 7.2 9.3 9.5 179.4 253.7 7.1 24.4 0.0 6.7 17.6 37.8 28.0 26.2 29.5 17.2 21.7 13.7 51.3 19.6 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 191.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 199.8;Hepatocytes: 287.4;Proximal enterocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 77.2;neutrophil: 113.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 113.7" "Cell line enhanced" "Detected in all" "BEWO: 96.9;RT4: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" 37.8 18.1 16.1 10.6 18.2 8.8 17.1 17.4 15.1 11.0 21.3 40.9 62.5 9.3 9.8 30.4 9.9 14.9 23.0 14.3 17.5 40.3 191.5 13.6 6.2 16.6 17.9 9.5 39.7 18.8 12.6 17.3 15.9 18.4 27.1 16.1 15.4 11.8 30.1 24.8 51.4 11.1 17.5 10.5 27.4 9.3 20.6 8.3 17.0 29.2 12.1 19.5 12.7 18.9 16.3 24.5 7.2 9.9 34.0 14.4 96.9 11.8 11.3 12.9 14.8 16.4 24.0 9.1 14.0 17.9 12.5 9.9 28.7 12.4 19.2 10.0 9.5 10.9 13.1 47.2 19.4 9.7 7.8 24.0 9.4 15.7 9.2 13.1 32.3 13.6 12.3 8.9 14.0 45.3 26.3 7.0 4.9 36.8 19.8 13.4 21.3 10.2 20.7 129.1 8.7 12.6 30.6 46.5 11.4 21.2 32.6 11.3 20.9 18.2 13.4 15.2 11.5 14.4 11.0 4.0 10.0 9.7 11.4 77.2 18.3 5.2 6.9 14.2 8.2 5.4 6.6 8.8 10.3 4.5 7.2 7.1 113.7 7.2 9.4 9.4 9.3 8.0 16.1 18.2 17.4 15.1 14.3 17.5 16.6 17.9 15.9 17.5 20.6 18.9 28.0 28.9 25.0 25.1 10.8 13.5 15.9 26.1 21.1 27.4 19.4 13.5 47.4 51.5 23.4 23.9 22.9 37.7 12.1 199.8 21.5 22.9 11.6 18.1 16.7 18.8 34.4 21.5 17.8 40.6 46.5 19.8 88.7 24.1 17.1 21.4 21.8 287.4 25.4 18.5 18.8 44.5 24.4 35.4 14.1 7.1 29.8 23.7 14.2 15.0 36.3 61.9 9.2 22.1 18.2 34.2 100.0 47.0 18.3 24.0 238.7 107.8 17.4 28.4 0.0 18.4 17.2 5.5 11.0 28.5 30.3 43.2 13.2 17.1 41.9 31.7 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Supported Peroxisomes NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" 7.7 8.8 5.8 6.4 5.2 4.4 12.2 3.8 7.2 9.5 5.9 8.4 8.9 5.6 4.3 26.6 6.6 5.9 16.2 5.3 4.9 6.5 14.9 7.2 6.6 5.9 4.6 7.5 12.0 7.1 4.5 8.4 4.7 10.5 6.3 3.8 15.4 8.4 6.4 12.5 8.9 11.4 4.2 5.3 10.1 2.9 5.0 4.6 8.5 5.6 8.5 10.1 13.7 7.1 8.9 9.6 10.5 14.1 11.0 18.7 17.2 11.1 15.1 18.5 16.1 4.8 11.7 11.9 11.7 22.8 25.0 5.4 4.6 14.4 14.3 4.1 4.5 5.2 8.2 14.8 18.3 10.7 9.4 18.9 12.1 16.7 6.5 13.3 22.1 13.1 7.0 10.6 16.1 8.2 11.4 15.6 5.9 11.3 16.4 11.8 17.3 14.3 11.2 12.4 5.1 11.7 14.2 7.2 7.3 8.6 7.2 14.9 21.7 18.2 5.9 7.5 11.8 7.9 5.6 5.4 23.2 13.1 11.8 0.1 13.2 3.3 6.1 15.2 6.3 5.4 7.1 7.8 17.8 4.9 6.5 6.7 3.1 9.5 14.4 21.4 10.4 9.4 5.8 5.2 3.8 7.2 5.3 4.9 5.9 4.6 4.7 4.2 5.0 7.1 6.2 6.4 5.9 14.7 4.8 4.5 7.6 12.3 8.6 8.2 11.6 7.6 9.4 10.0 9.8 11.0 33.3 23.9 7.7 10.9 3.9 17.3 4.4 13.1 4.2 5.6 1.8 3.0 13.2 13.7 9.3 6.6 10.2 10.0 0.0 21.7 4.6 14.2 10.2 1.7 14.2 4.9 14.2 4.1 4.4 3.3 6.8 5.3 5.4 6.5 7.6 3.8 2.1 12.5 14.5 16.9 7.4 11.3 5.6 9.1 18.3 8.2 11.2 18.6 0.0 3.8 6.9 2.4 2.3 14.1 5.8 74.6 6.0 6.0 7.5 11.4 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 5151.4" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 975.2" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "Hep G2: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 20000000 "Cluster 34: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favorable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" 2.1 0.8 0.5 0.4 0.4 0.4 4.3 1.2 1.0 1.5 0.0 0.6 164.1 0.2 0.5 0.8 0.3 0.4 0.2 0.4 0.7 1.5 5151.4 0.2 0.2 0.1 0.1 0.1 0.4 0.1 0.0 0.2 0.1 0.3 0.6 0.8 2.6 0.5 0.6 0.9 22.9 0.1 0.0 0.6 0.6 1.0 0.5 0.0 0.4 2.1 0.1 0.3 3.4 0.2 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.4 22.2 0.0 1.6 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.8 0.0 0.1 0.1 0.5 0.3 0.0 0.1 0.1 1.6 0.5 0.0 0.1 0.1 0.2 1.5 0.3 0.0 0.1 0.4 0.0 0.1 0.4 0.1 0.3 0.0 0.4 0.4 0.6 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 1.2 1.0 0.4 0.7 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 21.5 0.2 1.8 0.0 0.0 0.0 0.8 0.0 0.0 26.9 0.7 0.6 1.1 0.0 45.5 0.1 0.6 0.0 1.0 0.0 0.3 0.0 0.0 16.1 975.2 0.0 0.0 0.0 1.1 0.0 27.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.8 0.0 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 141.5 71.3 48.3 52.5 48.2 28.5 111.9 48.0 56.0 92.7 55.8 158.8 94.2 134.8 142.2 114.4 95.9 69.3 124.3 45.9 54.6 175.4 264.1 73.5 51.3 47.6 48.5 118.4 49.4 50.1 41.4 60.9 47.9 116.2 100.8 36.0 65.4 124.6 80.9 54.8 94.3 118.0 49.7 51.6 91.3 52.2 48.6 83.3 79.2 75.8 55.5 158.9 73.9 51.4 84.0 66.9 194.8 110.0 344.7 316.0 116.6 136.6 237.6 143.8 125.2 77.1 96.7 96.5 77.5 197.8 92.8 69.8 135.0 188.7 137.7 69.9 56.6 67.1 83.3 306.7 332.2 118.4 51.9 287.3 143.1 108.3 84.7 151.0 112.8 99.8 125.8 53.3 192.3 94.9 160.4 105.4 156.7 20.6 79.8 115.4 108.9 50.9 230.2 96.0 74.0 97.0 82.7 96.6 155.9 141.8 78.2 82.2 85.4 130.5 82.9 86.4 95.2 55.9 74.4 135.4 134.2 77.4 135.7 21.8 21.2 35.8 32.6 18.9 29.5 26.0 35.3 30.4 23.8 26.2 34.0 31.9 3.0 51.3 14.1 20.5 49.5 32.8 48.3 48.2 48.0 56.0 45.9 54.6 47.6 48.5 47.9 49.7 48.6 51.4 69.0 105.8 78.2 22.9 48.1 39.6 85.9 257.5 109.3 31.8 32.1 74.3 127.4 78.6 94.3 55.2 10.4 290.1 51.8 80.4 197.6 94.8 24.0 146.9 159.1 56.3 79.7 45.8 14.3 83.8 277.2 131.2 37.8 113.0 26.6 83.3 47.2 188.0 118.1 38.7 12.0 101.8 87.5 48.6 27.1 22.0 187.4 43.4 53.4 15.9 63.2 152.4 77.2 27.6 13.9 78.4 86.0 255.1 41.5 34.9 95.2 316.0 56.8 46.5 111.7 55.6 127.7 30.5 48.5 74.9 23.0 83.0 58.5 147.0 104.8 68.1 ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Group enriched" "Detected in some" 6 "Hepatocytes: 325.5;Proximal tubular cells: 92.4" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Hep G2: 44.7" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" 0.2 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 8.2 41.5 0.3 0.0 0.3 9.2 7.7 0.0 0.0 0.0 52.3 703.8 0.2 0.2 0.1 0.2 0.0 0.3 0.0 0.0 0.2 0.1 0.1 8.6 0.0 0.0 0.1 0.0 1.8 22.6 0.3 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 44.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 9.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.5 0.1 0.5 0.0 0.0 0.0 0.0 0.3 15.7 1.1 5.5 0.0 0.0 0.0 7.8 7.9 0.3 0.0 11.2 0.3 0.4 12.1 0.0 0.1 0.2 0.0 0.1 0.0 0.4 0.0 0.0 7.1 325.5 0.0 0.0 0.1 8.9 8.2 5.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 31.1 92.4 15.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 12.7 0.1 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 ADO "C10orf22, FLJ14547" ENSG00000181915 "2-aminoethanethiol dioxygenase" Q96SZ5 10 62804720-62808479 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 186.2;Late spermatids: 317.6;Spermatocytes: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039194, HPA040437" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA039194: AB_10794994, HPA040437: AB_10795633" "unprognostic (4.41e-2)" "unprognostic (1.44e-1)" "unprognostic (9.25e-2)" "unprognostic (1.73e-2)" "unprognostic (1.54e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.01e-5)" "unprognostic (4.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (4.24e-2)" "unprognostic (8.64e-2)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "unprognostic (7.46e-2)" "unprognostic (2.64e-1)" "unprognostic (4.59e-2)" 8.9 8.4 12.8 7.6 17.8 5.1 9.2 20.5 17.0 8.4 7.5 7.2 7.0 8.7 13.1 6.7 7.0 7.4 14.5 11.8 14.6 11.3 7.4 7.7 10.0 19.7 17.7 10.5 7.9 12.4 4.0 7.2 18.3 9.7 6.3 10.5 6.4 8.8 11.7 6.1 6.5 9.3 19.0 8.5 7.4 37.6 16.3 8.9 11.9 17.4 9.9 8.6 4.9 28.0 14.3 10.3 20.1 33.2 21.6 16.3 11.9 17.3 20.5 18.2 19.7 16.2 11.2 13.3 8.9 17.8 14.4 21.6 21.0 13.3 19.3 18.3 15.8 9.1 10.8 13.7 22.3 31.3 22.8 14.0 25.3 19.1 30.7 27.8 14.0 17.3 16.8 12.5 24.4 13.6 20.5 30.5 18.7 13.7 99.1 23.9 16.1 8.2 17.6 9.0 20.9 34.3 17.4 23.8 36.4 16.1 15.5 21.5 12.1 18.3 18.9 15.0 29.0 22.8 44.8 21.1 22.2 32.8 12.0 0.8 0.8 0.2 0.4 1.3 0.8 1.3 0.5 0.6 0.9 0.8 0.4 0.8 0.0 0.8 0.9 0.6 0.3 0.4 12.8 17.8 20.5 17.0 11.8 14.6 19.7 17.7 18.3 19.0 16.3 28.0 7.6 9.6 7.3 3.9 7.2 15.9 11.9 4.3 9.6 23.4 9.9 7.1 32.2 5.7 4.3 14.7 6.2 9.1 8.5 5.3 19.6 6.6 186.2 2.7 13.2 9.0 4.9 4.0 9.5 5.3 7.9 11.5 8.2 4.4 2.5 9.2 10.8 3.7 12.7 32.0 7.8 6.8 0.0 11.9 13.3 317.6 10.5 10.9 12.4 3.7 11.3 12.5 7.2 6.0 22.4 7.5 3.4 26.7 3.2 12.1 4.8 15.8 5.6 17.7 13.1 13.0 11.7 90.5 8.4 9.4 21.7 3.8 8.9 12.5 8.4 10.8 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 185.7 14.3 12.3 13.5 16.5 5.8 116.2 16.0 11.5 12.9 6.9 23.2 25.3 6.6 6.6 103.9 11.5 65.7 135.5 10.9 18.7 45.4 623.2 28.9 4.7 22.1 18.4 15.5 23.3 0.8 9.7 1.7 23.2 17.3 12.2 11.5 73.7 12.5 120.4 35.3 23.4 8.7 19.6 4.1 142.9 13.0 22.2 4.6 46.7 27.3 7.8 71.1 31.3 20.3 0.0 429.6 2.4 426.7 2988.3 358.2 0.2 13.7 95.9 5.4 4.1 8.4 0.5 0.0 6.1 97.7 72.5 3.6 1.6 22.4 2.5 0.1 0.2 12.6 65.6 5415.7 30.0 1.8 0.0 183.9 27.3 44.2 26.7 0.4 10.2 2.9 95.8 0.4 74.7 2.4 0.1 0.4 1.2 2297.1 1.5 0.1 0.8 4.2 24.3 81.4 0.4 1.7 23.8 0.7 0.8 1.3 0.5 7.8 85.3 36.0 2.3 97.6 4.5 1.6 0.5 0.3 129.3 12.1 0.9 1.5 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 0.1 0.2 12.3 16.5 16.0 11.5 10.9 18.7 22.1 18.4 23.2 19.6 22.2 20.3 21.6 67.3 34.4 2.0 2.4 21.2 27.8 253.8 262.4 3.1 7.6 1.0 3.2 284.5 144.5 62.5 0.0 0.1 0.2 5.9 13.7 67.0 24.0 3.3 1.7 17.1 1.8 52.6 3.4 328.0 0.1 176.3 139.1 4.6 4.5 0.8 21.0 597.7 0.4 0.0 3.1 6.8 20.3 16.1 15.6 9.9 151.6 3.3 106.7 13.1 4.6 51.5 0.0 4.5 0.5 120.2 3.6 147.4 0.4 41.3 20.2 61.9 72.2 4.5 0.0 16.4 24.3 1.9 1.1 229.3 20.5 0.1 2.1 6.4 20.3 306.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 613.3" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 6.6;OE19: 2.9" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 0.4 41.8 0.0 0.0 0.0 0.3 717.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.2 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 37.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.2 0.0 0.8 0.0 13.5 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 13.6 613.3 0.0 0.0 0.0 0.6 0.0 14.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.2 1.0 1.5 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138118305 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "liver: 426.9" "Group enriched" "Detected in some" 31 "Early spermatids: 65.4;Hepatocytes: 110.3;Late spermatids: 126.1" "Cancer enriched" "Detected in single" 77 "liver cancer: 20.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "Hep G2: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA057002 Enhanced Approved Nucleoplasm,Cytosol No NA 61000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA057002: AB_2683308" "unprognostic (2.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "prognostic favorable (9.91e-5)" "unprognostic (6.11e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (6.87e-2)" "unprognostic (2.94e-1)" "unprognostic (9.68e-3)" "unprognostic (2.90e-1)" "unprognostic (5.80e-2)" "unprognostic (3.11e-1)" "unprognostic (1.67e-2)" 0.0 0.1 0.2 0.0 0.1 0.2 5.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 426.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 12.6 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 65.4 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.4 110.3 0.4 0.0 0.2 0.2 0.0 3.2 0.4 126.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.1 1.6 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.2 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 996.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.4;CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.1 0.0 0.5 0.0 0.5 1.2 0.0 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 17.4 0.1 0.5 0.4 0.3 721.0 0.4 0.0 0.4 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.4 0.8 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.5 1.0 0.5 0.4 0.4 0.3 0.5 0.1 0.3 0.8 0.3 0.0 0.0 0.7 2.4 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.1 0.7 0.0 16.0 9.7 0.2 0.0 0.1 0.0 0.1 0.0 0.0 12.1 996.7 0.0 0.0 7.2 0.0 0.0 18.2 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 3.0 0.9 1.8 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.4 0.0 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Proximal tubular cells: 795.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 46.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" 45.0 96.6 23.3 4.3 25.8 3.5 39.7 27.0 27.3 46.6 27.1 31.8 39.4 31.2 16.6 27.2 43.4 14.9 46.6 20.3 27.8 162.1 70.5 35.9 6.7 28.4 26.5 54.8 23.2 30.8 29.2 7.7 27.0 31.9 10.3 8.5 32.8 14.1 24.6 26.1 39.6 9.6 25.2 21.2 38.9 14.8 28.2 17.5 62.9 16.7 7.3 37.1 37.3 26.5 3.1 5.3 26.5 10.0 30.4 29.4 3.4 6.7 17.8 6.9 10.6 3.4 11.8 12.4 11.1 10.2 2.1 1.5 17.3 10.1 8.2 8.2 8.5 1.5 6.4 8.1 15.0 7.4 2.1 24.8 9.1 10.6 2.6 23.0 20.7 14.3 8.0 5.5 24.1 1.0 37.2 6.3 9.6 2.0 2.1 24.5 30.7 7.9 46.4 3.6 4.5 12.0 12.8 6.7 7.9 9.6 5.7 5.3 9.9 10.7 3.4 5.5 3.7 8.1 7.9 12.5 11.8 8.9 5.4 2.6 2.5 0.2 7.6 1.4 8.8 4.8 6.6 6.0 3.2 6.7 9.8 10.4 0.4 6.5 0.2 5.0 10.2 4.0 23.3 25.8 27.0 27.3 20.3 27.8 28.4 26.5 27.0 25.2 28.2 26.5 37.7 32.1 57.8 33.6 10.2 30.3 47.1 59.4 36.5 2.5 31.9 36.1 9.6 64.3 46.9 108.5 0.0 7.9 19.0 18.0 211.3 58.2 1.9 60.6 45.5 30.3 22.9 16.4 1.2 21.3 18.5 75.2 41.8 27.9 19.6 39.1 27.8 71.6 20.4 3.3 3.8 24.4 46.8 10.9 16.9 4.8 69.9 12.5 23.2 14.0 14.9 50.4 14.4 3.5 21.8 23.0 18.6 77.8 8.0 18.9 162.3 795.7 48.7 3.8 13.1 40.9 36.5 0.9 4.0 25.9 26.7 3.4 18.2 52.6 37.6 37.5 CBR4 "FLJ14431, SDR45C1" ENSG00000145439 "Carbonyl reductase 4" Q8N4T8 4 168863770-169010275 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037499 Supported NA NA 51000 "Cluster 18: Basophils - Vesicular transport" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA037499: AB_10672386" "unprognostic (1.60e-1)" "unprognostic (8.25e-2)" "unprognostic (1.37e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (2.39e-2)" "unprognostic (2.41e-3)" "unprognostic (4.06e-2)" "unprognostic (1.29e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-1)" "unprognostic (6.64e-2)" "prognostic favorable (3.64e-14)" "unprognostic (1.97e-2)" "unprognostic (2.00e-1)" "unprognostic (1.81e-2)" "unprognostic (7.38e-3)" 9.1 14.1 11.2 7.9 13.1 6.7 14.1 13.1 14.4 9.4 12.4 12.1 12.8 9.9 20.1 8.3 9.3 8.1 17.8 11.1 12.4 27.3 49.6 7.3 11.0 12.8 12.3 11.0 10.0 11.7 9.9 8.1 13.4 11.7 13.9 17.5 13.2 11.2 17.3 15.7 11.8 8.8 11.7 9.4 10.8 7.5 12.7 9.7 15.6 15.9 11.5 8.4 8.4 15.9 9.0 6.6 20.2 12.8 17.2 20.3 4.1 6.3 8.6 7.5 6.9 7.9 9.3 18.3 3.4 4.9 7.0 9.4 18.8 20.1 8.2 7.0 9.3 32.3 16.9 10.7 10.3 12.9 10.9 13.4 17.1 5.4 9.1 17.8 22.4 15.3 17.8 14.4 12.0 4.6 13.5 21.0 7.3 6.2 10.0 11.6 7.1 8.0 26.5 9.4 17.9 13.4 7.7 10.9 16.7 16.7 11.7 8.2 13.4 7.8 4.2 8.8 6.4 14.2 10.2 8.8 13.6 15.6 4.9 7.9 4.0 6.4 6.6 3.6 3.9 5.7 4.5 6.4 3.5 7.5 4.9 6.4 3.0 5.8 5.3 4.8 4.0 2.1 11.2 13.1 13.1 14.4 11.1 12.4 12.8 12.3 13.4 11.7 12.7 15.9 16.1 0.0 9.4 86.2 24.2 23.1 32.2 27.7 10.8 37.3 20.7 12.1 30.0 28.6 19.9 49.7 39.6 40.6 19.8 24.2 50.9 66.5 16.1 22.5 17.5 20.5 29.3 34.9 68.0 42.9 27.5 17.8 16.8 15.8 2.5 36.0 24.7 81.6 24.9 62.2 82.3 26.5 34.6 26.6 8.9 34.6 44.4 16.8 35.6 61.8 26.1 28.3 46.4 150.3 135.8 37.6 39.8 31.2 8.7 24.6 31.7 93.4 19.8 51.3 59.2 18.5 16.3 56.6 41.6 15.3 20.2 20.2 15.9 38.3 27.4 29.6 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CH25H ENSG00000138135 "Cholesterol 25-hydroxylase" O95992 10 89205629-89207317 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Adipocytes: 125.9;Basal squamous epithelial cells: 224.3;Macrophages: 47.3;Microglial cells: 40.3;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 8.8;ASC TERT1: 4.4;fHDF/TERT166: 32.8;HSkMC: 8.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "spinal cord: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (6.07e-3)" "unprognostic (2.96e-3)" "unprognostic (1.57e-1)" "unprognostic (5.11e-2)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "unprognostic (8.65e-3)" "unprognostic (7.74e-2)" "unprognostic (4.76e-2)" "unprognostic (2.62e-5)" "unprognostic (2.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.29e-2)" 21.5 5.1 4.3 7.0 5.0 3.1 7.4 6.5 6.6 3.5 4.4 3.6 3.2 1.3 12.6 14.7 6.0 14.6 4.5 4.2 8.4 7.8 3.6 17.2 4.0 18.4 9.5 2.1 1.6 1.1 9.0 4.2 11.4 4.1 5.5 0.4 2.1 1.3 1.8 3.0 5.6 5.5 8.6 2.0 5.8 0.1 6.0 35.3 2.8 1.0 3.7 18.5 2.1 8.2 0.0 0.0 0.0 0.0 8.8 4.4 0.0 0.1 3.1 0.8 0.9 0.0 0.0 0.0 1.1 32.8 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 8.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 4.2 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 6.5 6.6 4.2 8.4 18.4 9.5 11.4 8.6 6.0 8.2 125.9 3.2 3.4 0.3 1.8 6.9 4.4 11.7 224.3 0.0 6.4 1.0 0.6 0.0 10.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 1.5 0.9 23.6 0.0 0.0 2.9 0.0 0.2 33.4 2.0 3.1 1.3 0.0 2.5 0.0 10.2 1.7 0.5 0.0 2.0 12.9 8.2 0.0 0.3 47.3 7.2 40.3 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.7 4.4 1.0 0.0 0.0 4.5 0.5 6.6 3.6 59.3 0.0 0.0 30.8 6.7 0.1 11.6 0.5 0.0 6.2 CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "ASC diff: 84.5;T-47d: 52.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039487 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA039487: AB_10672776" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" 68.0 28.3 24.3 15.9 25.4 39.1 62.4 25.2 25.7 54.9 33.8 34.3 17.3 31.2 52.3 29.3 41.5 19.2 25.2 24.0 24.5 39.2 101.7 30.8 19.1 26.1 23.0 54.0 35.9 14.9 40.9 13.0 24.8 50.3 16.0 16.8 34.7 19.8 19.6 59.6 28.5 19.6 20.2 37.5 31.9 27.7 24.7 14.2 36.0 7.7 14.1 25.8 37.6 36.7 3.7 6.8 16.0 6.8 84.5 34.4 5.7 14.5 3.2 6.0 5.0 4.1 8.8 4.9 10.6 7.7 2.0 12.6 7.1 11.2 3.5 6.6 8.6 7.8 19.4 8.8 7.6 3.3 4.9 42.6 13.8 9.0 11.2 30.8 5.6 10.4 8.4 42.8 5.7 30.8 1.8 9.2 3.1 1.9 6.3 6.6 1.0 11.4 8.0 9.6 8.0 6.3 14.3 19.9 5.7 9.9 52.7 6.5 12.6 17.5 3.4 5.2 4.2 12.2 3.4 2.6 14.7 8.3 7.1 3.7 2.0 2.5 1.3 1.1 0.8 1.1 1.8 0.8 1.0 1.8 2.4 1.4 16.3 1.6 1.3 2.3 3.4 0.5 24.3 25.4 25.2 25.7 24.0 24.5 26.1 23.0 24.8 20.2 24.7 36.7 23.5 3.2 22.0 40.1 15.6 16.6 28.3 18.3 4.0 29.0 27.9 43.4 8.9 20.0 17.4 23.9 16.7 12.2 18.5 19.3 3.9 12.6 0.7 11.6 20.4 22.5 14.4 0.4 47.0 9.1 6.9 23.0 19.4 14.3 9.5 22.0 21.4 38.2 8.4 26.9 51.1 21.3 14.2 11.9 12.8 3.5 27.1 11.1 14.2 30.0 15.6 18.3 20.6 34.2 62.4 10.0 25.5 30.9 6.9 28.8 22.5 5.1 15.4 30.0 39.5 22.5 27.9 48.0 64.4 5.5 18.3 8.9 13.0 17.9 15.4 24.2 CTBP1 BARS ENSG00000159692 "C-terminal binding protein 1" Q13363 4 1211445-1249953 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004217, HPA018987, HPA044971" Approved Enhanced Nucleoplasm NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB004217: AB_627312, HPA018987: AB_1847307, HPA044971: AB_2679161" "unprognostic (6.19e-2)" "unprognostic (4.78e-2)" "unprognostic (9.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (3.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.52e-2)" "unprognostic (1.04e-2)" "unprognostic (9.65e-2)" "unprognostic (2.24e-2)" "unprognostic (6.35e-3)" "unprognostic (3.58e-2)" "unprognostic (3.36e-1)" "unprognostic (2.46e-2)" "unprognostic (3.00e-1)" "unprognostic (3.22e-2)" "prognostic favorable (8.94e-4)" 76.1 88.1 92.3 86.1 91.2 71.5 72.7 96.6 104.3 94.7 73.6 94.6 91.0 98.4 47.5 85.0 89.2 61.4 100.0 92.7 98.1 88.4 109.2 82.6 108.7 99.2 94.1 93.5 141.1 58.8 140.0 45.7 94.6 94.8 41.9 38.8 90.9 50.8 170.1 74.3 97.1 48.1 77.1 118.7 79.5 47.3 90.0 98.1 86.2 91.5 62.4 87.5 79.8 89.8 108.5 156.8 118.4 146.6 81.5 58.6 101.7 83.4 76.8 101.8 102.8 135.0 255.1 131.0 93.8 97.5 156.6 84.1 72.3 109.9 30.4 101.0 86.6 119.1 185.6 177.1 135.7 108.4 163.3 101.3 82.5 86.5 49.8 97.8 76.8 147.1 138.1 219.6 56.9 178.1 351.4 338.3 140.5 87.8 148.4 244.4 71.4 173.2 65.8 135.9 222.0 138.1 79.6 85.2 114.5 70.9 187.2 164.5 99.7 168.5 94.2 97.8 182.1 157.7 164.3 155.2 133.4 166.4 135.6 12.6 15.6 17.4 31.8 23.1 24.0 20.1 22.3 27.4 20.6 19.3 17.1 25.1 12.7 23.9 23.9 34.6 20.9 16.1 92.3 91.2 96.6 104.3 92.7 98.1 99.2 94.1 94.6 77.1 90.0 89.8 33.3 41.7 39.0 17.9 36.8 34.2 21.1 22.1 13.1 32.1 52.0 39.5 54.9 37.1 19.2 36.8 4.2 25.4 72.4 57.2 11.7 29.4 4.0 34.0 46.4 35.7 46.1 42.3 19.4 40.6 32.0 37.5 37.8 41.6 24.1 31.2 45.0 85.0 43.0 40.4 21.2 49.7 20.3 72.9 31.8 5.5 45.1 37.7 46.2 21.5 45.9 46.8 82.4 19.6 17.7 45.0 35.7 35.7 42.0 36.9 42.8 37.4 25.7 17.8 6.6 31.2 32.9 10.8 13.4 30.3 37.8 19.8 41.1 32.0 57.5 27.9 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.2" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Cone photoreceptor cells: 66.7;Excitatory neurons: 53.0;Inhibitory neurons: 41.6;Rod photoreceptor cells: 28.4" "Cancer enriched" "Detected in single" 5 "glioma: 1.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Group enriched" "Detected in some" 4 "AF22: 2.4;U-937: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.16e-1)" "unprognostic (4.30e-1)" "unprognostic (2.50e-5)" "unprognostic (9.48e-5)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (4.01e-2)" "unprognostic (1.32e-5)" "unprognostic (5.21e-2)" "unprognostic (2.44e-4)" "unprognostic (5.97e-4)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (3.88e-3)" 1.9 2.0 45.7 0.3 96.2 0.0 0.8 20.1 66.7 1.4 17.5 0.7 0.2 1.5 0.9 0.2 1.0 0.4 4.7 52.7 34.0 1.4 1.3 0.6 0.6 25.3 32.0 1.6 2.1 1.9 16.6 0.0 26.2 1.4 0.2 5.1 1.4 0.6 1.1 0.4 0.5 0.8 23.5 0.2 0.7 2.5 38.2 0.4 1.7 0.5 0.1 0.9 0.7 39.0 0.0 0.0 2.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 45.7 96.2 20.1 66.7 52.7 34.0 25.3 32.0 26.2 23.5 38.2 39.0 3.5 3.2 6.0 58.1 0.7 1.7 6.4 0.0 1.2 11.5 1.8 3.3 7.0 2.8 1.8 1.8 66.7 0.2 8.7 0.0 1.9 0.2 0.7 0.9 5.0 7.6 0.0 0.0 53.0 1.1 0.3 4.0 0.5 0.6 1.3 2.1 2.9 3.4 0.6 8.4 41.6 0.0 0.0 2.1 3.0 1.3 4.7 0.9 3.6 6.5 1.1 20.8 0.0 23.6 11.8 0.1 0.1 4.1 2.2 4.1 0.0 7.4 0.9 28.4 0.0 8.1 3.9 9.4 5.3 0.0 1.4 0.1 1.5 2.7 0.1 3.5 CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "liver: 49.5" "Cell type enriched" "Detected in single" 17 "Hepatocytes: 7.0" "Cancer enriched" "Detected in single" 96 "liver cancer: 28.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-2)" "prognostic favorable (3.19e-4)" "unprognostic (7.60e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (8.43e-3)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.7;Oligodendrocyte precursor cells: 94.5;Oligodendrocytes: 119.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Group enriched" "Detected in some" 4 "HSkMC: 16.5;SH-SY5Y: 5.5;WM-115: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" 8.4 5.4 5.7 5.6 11.4 0.3 6.3 8.2 6.6 5.7 8.6 2.3 1.8 2.8 2.0 7.3 2.7 5.8 3.6 5.3 6.8 7.9 21.5 4.6 2.4 11.8 7.3 4.2 6.7 11.4 0.8 0.5 11.4 4.4 3.5 1.9 4.6 5.6 0.2 5.9 1.8 4.3 8.4 9.2 2.4 1.7 8.1 2.1 12.2 1.7 2.9 7.9 3.0 27.2 1.5 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 5.5 0.0 0.0 2.2 0.8 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.7 11.4 8.2 6.6 5.3 6.8 11.8 7.3 11.4 8.4 8.1 27.2 3.3 0.0 3.4 93.7 0.1 10.6 6.6 1.0 7.4 4.9 4.2 5.5 3.0 2.8 0.9 7.3 2.1 0.1 0.4 0.0 3.9 4.4 7.4 0.2 6.9 2.1 1.8 1.3 29.3 4.9 0.2 15.9 0.5 0.1 12.7 0.6 2.5 8.2 0.2 3.3 30.6 0.5 0.0 0.3 4.9 8.6 5.9 0.5 17.8 30.0 1.0 6.9 0.0 94.5 119.2 1.2 0.0 4.9 0.0 4.2 0.0 2.9 0.8 0.5 13.1 1.1 16.8 4.1 3.4 6.2 12.6 0.0 1.3 7.6 0.0 3.1 CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 920.2" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;SK-BR-3: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" 0.3 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.9 0.2 0.1 0.5 0.1 0.2 0.1 14.4 404.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 1.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.9 920.2 0.1 0.0 0.0 0.0 0.0 10.7 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 56.9;placenta: 72.6" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 1171.5;Distal tubular cells: 727.8;Syncytiotrophoblasts: 1735.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Hep G2: 372.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.0 4.1 0.0 3.3 0.0 0.2 1.7 3.8 0.1 1.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 4.0 1.9 56.9 1.1 0.0 0.0 2.1 2.5 0.8 0.5 0.7 0.0 72.6 2.2 0.1 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 1.9 0.0 0.0 1.6 2.8 0.0 0.0 0.0 0.0 0.7 0.1 2.6 1.6 0.8 0.1 32.6 0.0 0.0 10.3 0.1 0.0 0.0 0.0 6.5 2.0 0.0 15.8 0.0 1.2 7.5 39.9 1.0 0.0 1.1 7.3 0.0 3.0 372.7 0.0 0.0 5.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 9.7 0.0 0.0 2.1 0.1 0.8 1.1 1.8 14.8 0.0 0.0 0.0 0.1 9.4 0.4 1.2 2.3 2.8 1.6 0.9 0.6 3.9 0.2 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.3 1.7 3.8 4.0 1.9 2.1 2.5 2.2 1.9 2.8 2.6 0.0 0.0 0.0 3.6 0.5 0.6 1.0 0.6 2.8 0.0 0.2 3.4 2.3 1.5 0.0 11.0 0.0 1171.5 0.0 0.0 727.8 0.1 0.0 0.1 0.1 3.1 0.0 0.0 0.7 0.0 84.0 6.1 0.0 0.0 0.0 3.8 0.0 0.9 84.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.4 0.0 0.8 0.0 3.2 0.4 0.0 0.0 0.0 0.4 0.8 8.9 0.2 0.0 1735.1 0.2 10.8 0.1 1.1 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 8 "Inhibitory neurons: 392.8;Oligodendrocyte precursor cells: 146.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 20.1;HEL: 64.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 0.2 3.0 22.1 0.0 29.9 3.3 0.1 15.5 33.0 1.0 0.0 0.0 0.0 1.6 4.3 0.4 0.2 0.1 0.0 17.1 98.5 4.8 0.1 0.2 0.1 12.4 41.6 0.2 0.2 46.3 5.0 0.4 17.6 0.8 0.1 29.7 0.1 0.3 0.0 0.2 0.1 0.0 12.7 0.1 0.0 3.2 31.1 0.8 0.1 0.0 0.2 0.6 0.4 14.2 18.2 0.7 0.0 7.3 0.0 0.0 0.1 0.4 0.0 2.6 1.7 4.6 6.7 0.0 0.9 0.5 2.9 20.1 2.3 0.6 1.6 2.8 13.4 64.5 6.0 0.2 0.0 0.3 1.1 0.0 5.5 0.0 2.3 0.6 0.1 0.5 17.0 0.3 0.8 1.5 0.0 0.0 8.1 9.7 6.7 1.0 4.6 0.4 8.5 9.4 6.7 2.1 12.6 0.0 3.5 0.6 0.2 0.0 0.0 12.0 1.7 2.4 7.0 0.0 0.0 0.1 11.5 3.2 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 29.9 15.5 33.0 17.1 98.5 12.4 41.6 17.6 12.7 31.1 14.2 0.0 0.0 0.0 14.7 0.0 0.3 2.1 7.7 2.2 32.5 0.1 0.1 1.3 0.0 3.6 0.0 10.4 0.0 0.0 0.2 7.9 4.5 5.6 4.4 0.4 0.4 3.0 5.5 2.6 5.6 0.1 0.2 0.0 2.9 0.0 5.5 0.0 0.0 4.0 5.0 392.8 0.3 2.0 0.8 0.4 6.2 0.6 0.5 0.0 7.5 0.0 4.9 0.0 146.8 7.6 2.9 0.0 0.0 0.1 0.9 0.0 0.0 4.7 6.0 0.0 0.0 1.2 4.4 7.7 0.6 0.1 0.5 0.0 0.1 0.1 0.4 GAD2 GAD65 ENSG00000136750 "Glutamate decarboxylase 2" Q05329 10 26216665-26304558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 37.6;retina: 9.5" "Cell type enriched" "Detected in some" 13 "Inhibitory neurons: 293.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "SCLC-21H: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044637, CAB078177" Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB078177: AB_2665779, HPA044637: AB_10794053" "unprognostic (8.67e-2)" "unprognostic (1.11e-1)" "unprognostic (4.93e-2)" "unprognostic (2.52e-5)" "unprognostic (5.44e-2)" "unprognostic (8.08e-2)" 0.0 0.0 13.1 0.0 37.3 0.0 0.0 6.9 16.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.0 37.6 0.0 0.0 0.0 0.0 6.6 14.8 0.0 3.6 0.0 0.4 0.0 7.7 0.0 0.0 9.5 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 0.1 0.4 11.9 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 37.3 6.9 16.2 6.0 37.6 6.6 14.8 7.7 3.1 11.9 3.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 1.8 0.0 1.6 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 293.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.6 0.0 0.3 0.0 2.0 6.1 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 191.3;Distal enterocytes: 476.1;Intestinal goblet cells: 288.8;Paneth cells: 226.2;Proximal enterocytes: 270.2;Syncytiotrophoblasts: 114.5;Undifferentiated cells: 170.9" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 11.4;OE19: 29.0;RPMI-8226: 13.9;RT4: 13.9;SCLC-21H: 14.9;SK-BR-3: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 2.1 5.4 1.6 13.4 4.6 0.1 14.0 2.8 2.8 15.5 0.7 249.9 40.0 11.8 4.0 10.9 10.4 6.8 1.9 1.6 1.3 335.2 5.5 3.2 1.0 2.7 1.3 9.3 7.4 3.6 0.5 13.0 3.3 12.9 102.2 0.0 260.2 6.2 0.9 66.1 141.8 18.3 1.5 7.0 9.8 2.5 2.0 0.4 11.1 0.2 0.9 5.3 23.6 2.4 3.6 1.1 0.4 1.4 0.1 1.7 3.6 0.0 0.0 0.1 0.1 6.1 1.3 0.0 2.7 0.1 0.1 7.8 5.1 0.5 0.0 0.0 1.8 0.0 0.7 6.6 0.6 0.7 0.0 1.7 3.0 0.3 0.1 0.0 0.0 4.6 0.4 0.0 0.0 3.8 0.2 0.2 11.4 29.0 1.0 0.0 0.2 13.9 0.5 13.9 14.9 1.0 0.8 13.4 0.6 1.3 6.5 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.6 2.8 2.8 1.6 1.3 2.7 1.3 3.3 1.5 2.0 2.4 0.7 0.0 0.5 0.0 1.1 1.5 7.2 1.3 1.2 0.0 4.8 2.2 0.5 30.0 2.3 191.3 0.0 1.2 0.3 476.1 45.0 2.1 0.2 17.4 25.2 0.5 26.9 0.0 1.1 3.0 0.7 7.1 7.1 43.5 8.9 43.4 1.1 1.2 1.4 0.0 0.8 288.8 4.1 0.3 0.5 0.5 25.4 0.7 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.6 226.2 6.8 0.2 13.5 270.2 16.3 0.4 0.0 13.1 0.3 3.9 0.2 1.6 3.5 3.4 114.5 1.2 16.7 170.9 10.5 HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 288.6;liver: 241.6" "Cell type enhanced" "Detected in all" "Paneth cells: 498.6;Proximal enterocytes: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 768.7" "Group enriched" "Detected in all" 4 "granulocytes: 768.7;monocytes: 202.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 295.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" 56.0 64.1 15.0 33.0 15.7 109.9 45.5 19.7 18.6 44.0 18.8 139.6 216.7 57.5 28.2 21.5 44.2 107.7 21.0 15.6 18.4 75.9 241.6 104.4 41.5 20.1 17.5 60.6 54.5 10.9 13.1 47.2 18.9 25.5 145.8 8.2 14.8 34.2 12.1 14.5 288.6 49.4 19.3 42.7 36.6 10.1 16.7 36.3 19.3 26.3 34.9 41.8 33.5 22.8 1.0 45.4 22.2 56.1 66.5 92.4 31.2 23.4 39.3 16.1 29.9 38.2 295.2 0.0 45.8 26.2 14.8 0.9 65.6 5.2 18.0 72.1 13.8 63.3 22.9 131.0 37.6 114.8 114.0 65.3 1.7 22.5 7.4 51.3 31.5 27.4 67.9 32.7 30.1 1.8 24.0 144.8 37.8 146.7 7.6 63.2 20.4 77.7 45.5 70.0 7.2 69.3 47.5 1.6 87.0 28.2 0.1 112.7 24.9 11.0 47.9 43.1 13.0 15.0 6.6 7.1 20.1 80.6 77.0 591.1 202.0 442.9 62.5 142.7 74.8 57.1 62.6 64.6 108.2 47.6 55.8 64.2 768.7 82.3 125.8 36.8 77.4 171.6 15.0 15.7 19.7 18.6 15.6 18.4 20.1 17.5 18.9 19.3 16.7 22.8 169.0 314.1 179.5 13.4 89.0 28.0 77.0 16.0 10.8 1.8 5.0 6.2 5.3 368.9 83.7 44.1 2.1 30.6 63.1 356.8 25.4 53.9 1.2 9.0 28.1 101.8 93.7 68.8 16.8 58.6 59.7 77.3 28.1 18.8 100.1 34.1 112.5 337.3 129.1 18.5 14.7 180.8 18.3 220.4 176.2 5.1 104.1 139.1 67.6 43.1 197.3 36.3 113.3 16.6 19.0 65.9 498.6 59.5 60.8 39.5 1134.9 173.6 62.2 3.9 72.3 77.9 43.0 2.7 15.4 10.4 21.5 14.9 93.8 65.4 281.0 93.9 HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" 9.2 39.5 38.1 3.2 36.3 1.2 11.2 42.8 47.7 34.1 72.5 10.5 3.3 31.6 5.6 4.2 22.7 11.6 8.1 37.2 38.2 58.2 78.8 13.1 8.0 35.6 41.2 56.2 6.2 46.7 24.1 7.3 35.3 15.0 1.9 10.0 6.4 9.2 1.3 7.7 8.2 8.5 35.8 8.7 8.6 4.8 43.6 9.6 25.3 2.2 3.8 15.8 14.6 37.0 0.1 14.0 14.1 2.4 15.8 2.6 0.3 2.6 19.9 1.1 1.2 13.4 0.2 8.0 14.2 0.6 53.9 0.1 1.3 0.1 1.3 0.5 1.0 4.1 0.3 1.8 49.5 0.0 20.9 19.0 0.5 1.2 0.5 37.9 18.1 4.8 0.1 50.7 0.1 0.5 1.1 0.4 1.2 8.2 9.3 7.9 0.1 1.5 0.0 40.5 3.5 9.0 0.0 1.8 10.9 6.0 0.4 0.5 0.0 0.3 5.2 0.5 0.1 8.9 18.9 0.6 11.9 1.2 0.1 0.0 0.0 0.0 0.9 0.0 1.5 3.7 1.5 0.7 0.0 2.5 3.1 2.3 0.0 4.7 0.0 0.5 0.5 0.8 38.1 36.3 42.8 47.7 37.2 38.2 35.6 41.2 35.3 35.8 43.6 37.0 3.3 3.2 11.5 21.5 6.0 2.5 3.6 1.7 0.0 5.5 1.3 5.0 2.0 1.5 4.4 7.3 0.0 1.4 0.3 0.0 78.2 1.9 0.4 0.3 3.5 8.2 13.2 5.3 5.0 1.1 3.0 14.1 2.0 0.7 7.0 7.4 28.5 32.0 149.9 11.8 5.0 0.3 8.2 13.4 9.5 1.4 4.1 17.3 21.4 6.5 8.0 53.5 1.0 4.5 0.8 2.6 0.0 7.2 0.1 3.8 2.2 434.5 0.7 1.6 0.0 2.4 2.9 5.6 15.7 0.3 1.8 2.2 2.8 7.5 0.2 2.9 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 42.5;Hepatocytes: 68.9;Hofbauer cells: 53.9;Proximal enterocytes: 45.3;Proximal tubular cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Cell line enhanced" "Detected in many" "HDLM-2: 91.0;Hep G2: 66.2;HMC-1: 98.1;U-2197: 96.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" 27.3 25.7 5.7 10.9 6.2 4.4 17.1 14.7 9.1 8.5 3.5 15.9 19.5 9.5 2.1 12.3 9.4 11.5 11.7 5.9 5.9 27.7 136.5 11.2 8.4 6.3 5.4 8.6 25.6 8.0 5.4 4.5 6.6 8.2 5.8 1.6 10.0 4.5 7.0 18.5 18.4 9.8 5.6 16.3 11.1 6.0 7.1 2.8 6.3 4.5 5.5 13.9 8.7 6.9 20.3 23.2 2.4 11.5 7.9 28.5 1.4 24.8 38.7 4.8 10.0 1.7 34.4 1.2 8.1 30.3 0.8 6.1 2.2 3.6 2.4 91.0 5.4 1.6 18.6 66.2 7.4 0.5 98.1 13.7 6.0 23.1 4.6 11.2 2.2 1.2 4.9 1.0 18.3 43.6 0.6 14.4 1.9 8.5 3.2 2.5 7.8 22.3 15.1 1.3 8.4 4.1 3.2 15.9 2.2 1.1 31.1 1.6 11.5 10.0 2.8 96.1 2.7 1.6 15.4 1.1 39.1 2.5 0.8 61.8 1.4 27.3 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.2 0.0 0.1 1.2 0.5 0.0 0.6 0.0 0.7 5.7 6.2 14.7 9.1 5.9 5.9 6.3 5.4 6.6 5.6 7.1 6.9 7.6 3.2 4.2 3.3 1.2 7.9 2.6 4.1 4.0 0.7 13.6 9.8 1.7 27.1 2.2 14.7 0.0 2.0 0.5 10.8 15.6 42.5 37.5 1.9 7.1 11.1 7.8 4.8 0.2 30.3 3.5 26.0 8.2 4.2 9.5 9.0 6.8 68.9 53.9 1.7 0.4 11.4 6.1 7.3 15.9 2.2 6.5 11.4 14.2 0.0 12.8 2.1 0.0 0.5 1.2 20.7 14.0 5.3 1.9 1.8 45.3 46.7 1.3 0.5 13.1 9.4 6.3 0.8 1.2 4.9 12.6 1.4 1.7 6.5 23.5 2.8 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" 52.0 67.1 45.5 38.5 50.0 60.3 49.9 47.8 61.3 44.1 46.5 57.2 52.3 50.7 23.5 50.2 44.8 35.0 91.9 54.9 48.8 68.5 49.2 42.0 40.3 50.5 45.7 49.3 48.3 45.5 47.9 28.3 52.3 43.8 34.6 24.4 51.7 39.9 100.5 51.7 54.7 34.5 43.9 51.8 52.2 32.1 49.1 35.2 48.0 82.9 34.9 44.3 43.2 47.2 94.9 90.0 47.3 65.9 74.4 59.4 62.0 47.3 64.1 80.5 84.3 76.0 66.5 121.4 80.2 74.7 68.2 67.2 72.6 69.2 30.0 38.9 101.7 43.0 118.9 59.0 85.5 61.6 87.5 76.1 48.0 64.4 69.4 50.4 65.3 50.3 24.7 60.4 64.7 138.5 72.0 76.0 21.6 84.2 118.0 62.7 43.3 105.8 94.4 61.1 59.5 42.8 30.2 96.3 48.0 20.8 39.6 51.9 56.0 49.9 34.1 76.8 112.5 89.0 22.6 152.1 81.8 75.8 57.6 178.1 159.3 165.8 71.8 163.9 68.0 68.5 73.2 71.2 163.1 78.9 57.9 63.7 57.8 86.5 169.6 101.3 107.5 140.1 45.5 50.0 47.8 61.3 54.9 48.8 50.5 45.7 52.3 43.9 49.1 47.2 44.4 35.3 33.8 5.5 49.2 80.9 67.5 103.9 37.5 34.9 48.4 57.9 55.1 50.1 55.0 51.5 29.2 99.8 48.2 145.0 207.4 93.4 132.0 42.2 39.4 44.6 62.3 41.4 5.6 90.5 98.7 48.2 47.9 39.8 93.8 43.6 43.2 35.4 131.0 18.5 6.4 107.0 79.3 98.0 77.0 284.2 53.4 75.6 67.6 3.7 116.4 50.8 64.9 3.0 5.0 73.5 133.8 58.6 49.7 35.6 222.4 253.1 50.7 49.3 52.6 47.4 68.2 15.9 18.3 50.3 77.4 110.8 55.2 103.0 112.7 64.2 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.7;fallopian tube: 22.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Early spermatids: 186.0;Endometrial ciliated cells: 50.1;Late spermatids: 33.7;Respiratory ciliated cells: 100.5;Spermatocytes: 114.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 3.6;SCLC-21H: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA073761 Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA073761: AB_2732241" "unprognostic (1.03e-2)" "unprognostic (9.44e-2)" "unprognostic (1.58e-1)" "unprognostic (9.84e-2)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (2.01e-1)" "unprognostic (3.66e-2)" "unprognostic (3.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (7.84e-3)" "unprognostic (3.01e-1)" 0.4 1.5 2.2 0.2 2.5 0.1 1.2 1.9 2.4 1.7 15.7 1.2 0.0 1.7 1.7 0.5 22.5 0.8 1.3 2.4 2.8 3.1 0.3 2.0 0.3 4.2 5.3 1.0 0.9 4.2 9.3 0.0 3.9 0.9 0.5 8.5 1.0 1.3 0.4 0.4 0.3 0.8 3.5 0.2 0.7 24.5 2.8 0.5 4.8 0.5 0.2 0.5 0.4 3.0 0.3 1.2 0.9 2.5 0.1 1.1 0.3 0.0 0.4 0.5 0.3 0.1 0.8 0.5 0.5 0.1 1.1 0.6 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.8 0.5 0.4 1.2 0.7 0.2 0.0 0.1 0.5 0.7 1.1 0.0 0.7 0.3 1.5 0.8 0.3 1.6 0.1 1.4 1.6 0.9 0.0 3.6 0.2 3.5 0.7 1.1 0.5 0.3 0.5 1.1 0.0 0.0 0.6 0.6 0.1 0.3 0.3 1.6 0.2 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 1.9 2.4 2.4 2.8 4.2 5.3 3.9 3.5 2.8 3.0 0.2 6.4 1.5 6.8 0.0 0.8 1.4 3.9 1.8 3.0 2.1 2.4 1.3 2.8 6.4 0.0 0.0 0.1 0.0 0.0 13.7 1.3 186.0 50.1 1.2 0.6 1.2 0.0 8.9 0.0 0.1 1.3 1.5 1.6 0.0 1.1 0.0 0.0 0.1 3.3 6.3 0.0 10.2 0.0 0.2 33.7 1.8 0.5 1.8 1.9 0.0 9.6 0.0 1.0 1.3 0.1 0.0 3.0 0.0 0.4 0.0 6.0 100.5 10.2 0.0 0.5 1.7 114.9 5.1 0.5 0.3 0.0 0.2 1.6 0.1 0.9 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 PDZD4 "FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L" ENSG00000067840 "PDZ domain containing 4" Q76G19 X 153802166-153830565 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 150.1" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Bipolar cells: 18.0;dendritic cells: 14.0;Excitatory neurons: 11.0;NK-cells: 26.8;Rod photoreceptor cells: 14.1" "Group enriched" "Detected in many" 4 "glioma: 20.1;testis cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.4;NTERA-2: 12.4;RH-30: 17.3;SCLC-21H: 29.5;SH-SY5Y: 28.7;U-2 OS: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003878 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003878: AB_2162807" "unprognostic (9.18e-3)" "unprognostic (1.25e-1)" "unprognostic (1.11e-4)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (1.85e-2)" "unprognostic (1.92e-3)" "unprognostic (2.17e-1)" "unprognostic (2.32e-3)" "unprognostic (5.90e-2)" "prognostic favorable (2.96e-5)" "unprognostic (2.27e-1)" "unprognostic (2.54e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.83e-2)" "unprognostic (2.87e-2)" 3.7 5.0 98.2 1.9 102.8 2.1 3.4 76.6 150.1 9.5 42.3 23.4 1.6 11.9 1.2 3.8 13.9 2.0 6.1 132.0 46.9 3.9 2.6 4.8 2.0 57.6 48.0 2.7 2.3 2.8 44.1 0.1 59.5 10.4 1.3 14.8 4.1 9.8 3.3 4.3 5.9 4.3 38.2 14.0 7.6 6.0 46.7 1.1 3.5 1.3 0.6 10.0 9.2 89.8 0.0 1.6 24.4 6.4 0.0 0.1 0.0 0.7 0.0 0.7 0.8 0.6 0.0 0.0 0.3 0.0 7.9 0.1 4.5 0.0 0.1 0.0 0.8 0.0 1.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.3 5.0 0.2 0.9 12.4 0.0 0.3 0.1 17.3 0.0 0.0 0.1 29.5 28.7 1.3 0.0 9.2 8.2 2.8 0.3 0.0 0.0 14.1 0.3 1.8 0.0 0.1 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.2 98.2 102.8 76.6 150.1 132.0 46.9 57.6 48.0 59.5 38.2 46.7 89.8 1.8 0.0 0.0 12.1 0.1 0.3 0.0 0.0 0.6 18.0 0.1 2.4 3.7 0.0 1.3 0.0 6.2 0.0 14.0 0.0 0.0 0.0 0.1 0.2 1.5 3.5 1.8 0.8 11.0 0.2 0.0 0.8 0.5 0.1 1.3 0.2 4.6 0.1 0.0 1.7 8.6 0.0 0.0 1.0 0.0 0.2 0.6 0.1 3.6 4.7 0.2 3.9 26.8 5.5 0.7 0.3 0.0 3.8 3.6 0.2 0.0 0.0 4.4 14.1 0.0 1.7 2.1 0.3 4.1 0.5 0.9 0.0 4.1 0.0 0.0 0.2 PLXNB3 "PLEXB3, PLEXR, PLXN6" ENSG00000198753 "Plexin B3" Q9ULL4 X 153764196-153779346 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 210.2;intestine: 57.2" "Group enriched" "Detected in some" 8 "Astrocytes: 43.8;Oligodendrocytes: 72.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "WM-115: 70.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048046 Enhanced NA NA 390000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA048046: AB_2680239" "prognostic unfavorable (6.13e-4)" "unprognostic (2.60e-1)" "unprognostic (9.10e-4)" "unprognostic (2.30e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-3)" "unprognostic (1.29e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-1)" "unprognostic (2.66e-1)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (9.73e-3)" "unprognostic (1.98e-2)" 14.7 28.8 74.4 2.0 122.8 0.7 16.0 86.1 110.8 10.8 28.7 57.2 2.3 23.6 3.9 7.0 11.9 4.9 9.6 77.4 83.0 1.8 1.1 2.8 0.5 105.0 102.2 1.8 6.5 0.2 3.1 0.4 101.5 16.6 2.0 2.4 26.3 8.5 0.8 10.0 9.3 6.5 71.3 0.7 13.6 11.5 123.9 0.1 1.7 0.4 0.3 20.8 13.0 210.2 9.3 1.1 1.1 0.7 1.2 0.7 0.7 8.5 1.7 1.1 3.0 0.0 0.1 0.0 5.4 2.4 1.6 1.0 0.0 7.2 0.9 0.1 0.0 5.8 12.0 6.6 2.3 0.0 0.6 1.8 5.2 5.2 3.2 19.8 3.4 0.2 0.5 3.1 2.3 7.6 0.1 1.4 0.2 6.3 14.0 2.8 0.9 0.1 1.4 4.2 2.4 7.5 0.4 7.8 20.2 0.2 10.4 0.0 15.0 8.6 4.4 6.8 10.9 3.0 0.8 0.2 18.6 0.5 70.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 74.4 122.8 86.1 110.8 77.4 83.0 105.0 102.2 101.5 71.3 123.9 210.2 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 1.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 6.6 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 40.9;Excitatory neurons: 29.0;Extravillous trophoblasts: 63.9;Granulosa cells: 46.9;Syncytiotrophoblasts: 49.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AN3-CA: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.2 43.7 1.9 48.8 0.0 0.6 6.5 53.3 1.3 4.8 81.7 3.4 6.5 1.7 14.0 4.1 2.6 6.5 49.8 40.8 1.9 0.2 0.6 0.0 19.6 22.8 0.9 0.3 0.5 1.8 2.0 21.1 17.2 3.8 7.9 0.4 37.6 2.0 1.8 13.4 15.7 15.0 0.2 15.9 8.8 65.1 1.4 0.3 0.3 0.1 27.4 2.2 28.5 0.3 0.1 0.4 33.9 0.0 0.0 3.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.3 0.4 0.3 0.2 0.7 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.7 0.0 0.1 2.7 0.9 0.3 0.4 0.0 0.2 1.2 0.0 0.2 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 48.8 6.5 53.3 49.8 40.8 19.6 22.8 21.1 15.0 65.1 28.5 0.0 0.0 0.0 18.9 0.0 0.6 0.4 40.9 0.0 21.6 0.3 0.9 3.0 0.0 18.0 0.0 22.9 13.5 0.1 1.7 0.0 0.4 0.3 0.3 4.4 0.3 0.0 0.0 29.0 0.4 63.9 0.5 0.0 0.3 0.0 46.9 0.0 0.0 2.4 0.0 24.2 1.1 12.2 0.0 0.0 0.8 0.0 0.3 1.8 1.0 0.0 3.2 0.0 11.1 13.2 2.9 0.1 0.4 0.0 0.3 20.3 0.4 2.6 19.4 0.0 0.0 4.0 0.6 0.9 0.0 0.6 49.5 0.1 0.6 0.4 1.0 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1116.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 1240.7;Proximal enterocytes: 769.0;Proximal tubular cells: 881.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 640000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes Nucleoplasm "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favorable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favorable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" 203.7 125.5 68.5 92.7 71.6 111.2 196.6 74.2 90.1 153.8 79.2 256.7 336.3 94.6 165.5 140.2 119.7 144.6 162.4 65.8 76.1 319.8 1116.8 140.6 106.0 75.4 72.3 94.5 119.2 130.9 64.7 79.0 77.9 150.9 270.5 76.6 114.0 97.3 142.0 130.6 305.7 112.9 75.6 83.9 234.4 63.4 74.7 131.9 140.9 152.8 125.5 139.2 76.9 78.9 120.6 64.8 85.5 157.9 273.6 232.6 92.7 140.0 208.9 90.1 129.2 58.7 127.5 114.7 147.6 206.6 105.3 82.5 59.6 131.0 136.5 168.2 86.4 123.4 88.8 122.1 182.0 179.9 197.5 190.2 175.0 107.1 52.9 196.2 260.0 132.6 111.5 58.2 184.7 70.1 200.7 155.2 94.6 304.4 126.0 101.9 150.9 158.3 252.2 192.2 70.9 85.3 122.0 246.3 121.6 189.6 125.9 201.4 203.8 122.4 63.4 213.2 114.9 95.9 131.0 134.2 159.0 175.7 113.8 285.6 193.7 286.0 185.9 208.8 152.1 150.8 144.9 184.6 230.5 132.6 120.8 171.4 29.4 176.8 204.2 150.9 195.2 289.5 68.5 71.6 74.2 90.1 65.8 76.1 75.4 72.3 77.9 75.6 74.7 78.9 167.0 134.6 198.4 52.2 91.1 150.4 123.8 222.2 110.4 37.5 189.8 86.0 157.4 258.7 166.2 185.8 31.3 182.7 128.3 512.7 473.5 168.1 57.4 150.4 81.6 126.8 235.1 93.4 45.0 162.4 156.5 124.3 180.4 125.3 138.4 54.0 146.7 1240.7 203.5 42.1 54.4 462.7 250.3 230.1 173.1 51.4 184.2 148.8 192.1 42.2 154.6 132.0 181.3 48.2 44.3 157.4 503.4 171.9 76.6 118.1 769.0 881.0 178.2 34.1 78.9 72.0 110.6 20.4 19.4 150.0 170.8 133.9 132.9 110.3 336.4 187.8 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SDR42E2 ENSG00000183921 "Short chain dehydrogenase/reductase family 42E, member 2" A6NKP2 16 22165583-22191754 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 3.2;choroid plexus: 1.8;fallopian tube: 2.1;pituitary gland: 1.2;testis: 2.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 38.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 4.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.9" "Cell line enriched" "Detected in single" 6 "RPMI-8226: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.03e-3)" "unprognostic (2.80e-1)" "unprognostic (2.06e-1)" "unprognostic (1.72e-4)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (8.77e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.32e-3)" "unprognostic (2.01e-1)" "unprognostic (7.09e-2)" "unprognostic (4.76e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (6.61e-2)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.4 1.2 0.4 1.8 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.6 0.2 0.0 0.0 0.4 0.0 1.5 3.2 0.1 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 0.3 0.5 0.3 0.3 0.1 0.8 0.5 0.3 4.9 0.4 0.1 0.3 0.3 0.2 0.6 0.7 0.4 1.2 0.6 0.2 1.5 3.2 1.0 1.2 0.4 0.8 8.9 0.0 2.4 2.6 8.7 0.8 0.7 0.9 0.6 7.7 5.2 11.6 1.9 10.0 0.4 0.0 0.0 0.9 7.4 15.6 0.0 0.9 1.8 3.9 8.4 2.6 2.4 5.7 2.0 0.5 0.3 2.6 12.8 3.2 2.5 1.7 5.0 3.4 2.3 5.0 0.7 15.1 4.1 13.1 3.8 1.4 5.9 5.1 1.8 0.0 6.4 14.7 10.3 0.5 0.4 0.3 3.2 1.5 5.9 1.1 38.2 0.6 3.5 3.7 0.0 0.9 3.0 0.6 0.6 1.4 1.7 1.4 11.1 2.6 8.8 0.3 SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Suprabasal keratinocytes: 4.0" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" 0.1 0.0 0.1 0.0 0.1 0.0 2.6 0.2 0.3 11.3 0.0 0.3 0.0 0.4 0.0 14.5 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.1 0.0 0.8 58.5 0.1 0.0 0.0 0.2 0.1 0.8 0.0 0.5 0.0 0.0 7.5 0.2 21.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.0 0.0 0.0 0.0 0.0 0.0 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC27A5 "ACSB, ACSVL6, FACVL3, FATP5, FLJ22987, VLACSR, VLCS-H2, VLCSH2" ENSG00000083807 "Solute carrier family 27 member 5" Q9Y2P5 19 58479512-58512413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Ligase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 1023.6" "Group enriched" "Detected in many" 4 "Early spermatids: 144.4;Hepatocytes: 439.9;Late spermatids: 464.4" "Cancer enriched" "Detected in all" 26 "liver cancer: 49.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA007292, CAB056160, CAB068239" Enhanced NA NA "Cluster 30: Non-specific - Translation" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "CAB056160: AB_2665590, CAB068239: AB_2665592, HPA007292: AB_1857064" "unprognostic (5.97e-2)" "unprognostic (9.12e-2)" "unprognostic (9.95e-2)" "unprognostic (6.36e-3)" "unprognostic (2.52e-1)" "unprognostic (7.46e-2)" "prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.66e-4)" "unprognostic (2.27e-1)" "unprognostic (3.33e-2)" "unprognostic (7.80e-2)" "unprognostic (2.16e-1)" 5.9 9.9 35.8 3.3 36.3 3.7 6.5 34.5 49.9 7.5 32.7 7.7 2.5 5.4 2.9 5.4 9.1 2.9 6.6 35.4 36.0 11.0 1023.6 4.0 4.4 35.3 36.7 6.8 10.6 7.1 10.8 1.6 35.2 8.0 1.7 3.0 9.9 4.5 4.8 6.6 3.9 4.4 35.4 5.2 7.2 20.7 38.2 6.2 6.6 4.3 4.6 8.2 6.2 34.9 41.2 55.0 9.6 10.2 9.0 9.3 6.1 2.3 5.3 7.5 10.3 4.4 8.7 52.9 6.5 2.8 1.4 8.4 11.0 35.3 3.2 24.8 37.0 35.8 58.3 46.7 13.5 18.9 12.2 10.9 5.9 1.2 20.5 12.9 3.9 39.4 33.5 0.0 9.1 33.4 47.2 39.8 5.8 34.4 31.9 23.4 0.2 72.6 25.0 19.3 13.1 17.8 0.1 53.5 12.1 2.7 15.8 16.3 3.1 0.0 6.8 0.0 4.7 33.5 41.0 22.7 10.9 35.0 2.0 0.1 4.0 3.8 13.5 5.3 29.6 24.3 17.5 18.0 10.8 15.8 21.3 21.7 0.5 18.1 4.0 18.2 23.3 13.9 35.8 36.3 34.5 49.9 35.4 36.0 35.3 36.7 35.2 35.4 38.2 34.9 12.5 0.0 7.3 3.3 9.8 9.1 15.5 16.0 14.2 11.8 50.1 73.2 8.3 20.0 9.9 5.5 0.0 7.3 6.9 4.6 39.2 9.6 144.4 12.4 10.1 11.3 10.1 25.0 4.3 15.4 3.3 8.9 8.6 8.0 5.1 20.2 16.8 439.9 10.5 10.1 5.3 4.7 6.1 16.7 9.6 464.4 10.8 6.7 16.0 1.9 3.4 12.0 12.3 5.0 7.4 8.0 1.2 9.4 8.9 32.2 1.8 57.6 11.5 8.5 6.6 7.4 18.4 50.9 12.7 15.5 14.1 3.4 11.3 26.7 6.1 15.0 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 211.4;tongue: 76.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 25.0;Cone photoreceptor cells: 8.4;Oligodendrocytes: 7.4;Skeletal myocytes: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 47.0;U-266/70: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 4.3 12.5 2.2 15.8 2.1 1.4 20.2 19.2 3.2 8.7 17.0 3.3 8.4 1.6 6.5 2.9 1.5 47.3 12.2 12.8 1.6 0.7 1.1 2.2 14.6 14.3 2.3 1.6 1.4 18.7 0.5 14.5 7.8 1.7 1.7 7.6 1.1 211.4 5.7 3.9 3.1 11.4 1.9 5.0 1.1 16.0 0.3 0.6 76.8 0.1 6.7 2.7 23.4 5.1 6.7 1.2 3.3 0.0 0.2 1.5 0.6 0.0 0.3 0.1 5.7 0.9 5.1 0.6 0.6 0.5 1.4 0.0 0.1 0.0 4.4 4.6 2.7 5.1 0.9 0.1 1.3 7.6 4.1 0.0 0.0 0.0 0.3 0.0 7.1 3.5 5.8 1.3 10.8 1.0 7.5 1.2 0.3 1.8 2.3 47.0 1.5 0.1 2.3 8.0 3.8 0.0 3.5 1.6 0.5 4.4 5.8 0.1 1.8 4.2 3.5 0.7 19.4 3.5 3.3 1.0 9.5 2.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 12.5 15.8 20.2 19.2 12.2 12.8 14.6 14.3 14.5 11.4 16.0 23.4 0.1 0.0 0.0 3.3 0.0 0.6 1.0 0.1 0.0 4.3 2.5 1.0 25.0 0.0 0.1 0.0 8.4 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.2 0.5 1.2 0.0 0.7 0.0 0.1 1.1 1.5 0.2 0.0 0.2 0.0 0.0 0.0 1.7 1.8 4.0 0.0 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.1 0.5 0.0 0.5 7.4 0.0 0.0 3.0 0.2 0.7 0.0 0.0 0.1 0.5 0.0 18.9 2.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.6 0.4 SSR4 TRAPD ENSG00000180879 "Signal sequence receptor subunit 4" P51571 X 153793516-153798499 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 3119.7" "Cell type enhanced" "Detected in all" "Plasma cells: 6002.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045209 Enhanced Supported "Endoplasmic reticulum" NA NA 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA045209: AB_10961407" "unprognostic (3.56e-2)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" "prognostic favorable (1.76e-4)" "unprognostic (8.74e-2)" "unprognostic (5.57e-2)" "unprognostic (7.99e-2)" "unprognostic (4.58e-2)" "unprognostic (2.10e-1)" "unprognostic (5.04e-3)" "unprognostic (5.74e-3)" "unprognostic (8.76e-2)" "prognostic unfavorable (5.51e-6)" "unprognostic (8.18e-2)" "unprognostic (2.24e-1)" "unprognostic (6.01e-2)" "unprognostic (5.33e-2)" 213.5 311.6 152.0 232.1 153.6 498.9 252.7 157.1 186.5 319.0 195.6 366.6 341.6 192.4 885.6 233.5 201.7 185.2 295.2 148.9 190.3 203.4 397.6 236.5 319.0 161.8 156.3 182.8 3119.7 157.1 676.5 120.5 159.2 263.8 267.7 37.1 922.8 416.4 127.4 191.5 256.6 120.5 162.7 396.6 495.0 160.9 158.1 158.0 221.0 74.1 324.6 243.8 217.3 171.5 344.2 428.9 148.7 834.4 785.2 412.4 299.5 278.6 431.1 299.9 407.3 547.9 298.3 476.9 721.8 450.4 262.4 332.8 259.2 270.6 111.8 192.6 212.0 128.4 380.1 446.0 669.0 370.7 352.6 511.9 376.6 256.9 353.2 265.3 327.4 240.8 145.4 1027.1 239.8 616.8 222.3 578.1 90.8 941.3 685.7 247.3 178.4 922.7 394.2 413.9 285.8 228.8 159.3 301.7 333.1 161.9 188.8 821.6 263.9 174.4 189.9 324.4 377.5 1449.6 774.0 576.4 364.7 630.8 295.7 652.3 594.6 286.7 616.7 476.9 762.6 695.6 629.2 613.7 598.0 644.7 538.8 555.2 93.8 697.3 396.5 1751.9 515.9 1330.5 152.0 153.6 157.1 186.5 148.9 190.3 161.8 156.3 159.2 162.7 158.1 171.5 228.6 166.7 301.9 7.5 824.1 257.2 372.4 566.8 167.9 53.6 451.1 380.1 334.8 357.4 464.7 318.2 56.3 311.4 521.0 473.2 168.3 544.9 476.1 276.9 513.6 263.0 747.5 175.3 3.6 627.4 700.6 357.3 344.0 454.8 352.2 257.0 241.3 723.3 439.0 35.3 5.3 967.6 547.3 339.1 416.6 1753.1 336.7 344.5 1428.3 4.7 409.3 174.7 432.5 8.0 11.1 487.0 595.8 247.1 6002.3 633.3 581.0 414.8 340.6 83.4 118.3 174.3 300.7 199.4 207.9 306.1 322.2 564.6 473.4 600.1 548.8 490.0 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7147237-7804358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.8;Excitatory neurons: 32.2;Inhibitory neurons: 39.3;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.5;RPMI-8226: 69.8;U-266/70: 110.2;U-698: 47.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 18.2 4.6 3.7 4.5 4.8 2.1 5.8 4.0 12.1 5.6 1.3 6.8 2.8 4.3 2.4 3.1 4.8 7.3 6.6 4.2 3.7 4.8 8.7 8.7 4.1 5.8 6.1 4.7 3.0 2.8 1.2 26.6 5.5 5.2 5.9 6.1 3.1 5.6 5.2 4.9 3.2 6.8 1.3 4.7 12.0 2.4 12.1 4.4 3.9 6.6 3.6 9.4 3.9 7.8 11.5 3.7 7.5 3.0 48.5 24.9 37.5 22.3 7.8 5.8 5.3 19.2 11.2 21.4 5.0 15.5 5.0 3.0 5.4 3.9 5.8 3.3 8.6 1.8 12.7 5.7 2.7 3.8 11.5 8.3 0.7 3.8 2.3 4.0 8.8 2.0 1.4 23.5 15.2 2.9 2.2 3.1 3.3 0.2 4.8 3.9 4.8 69.8 14.2 16.0 5.6 4.8 4.7 8.3 3.0 11.8 3.8 1.6 15.8 22.5 2.2 30.0 4.4 110.2 0.8 47.2 5.9 3.0 6.5 0.9 1.7 0.4 0.4 2.0 0.2 0.4 0.2 0.2 0.9 0.7 0.1 0.3 1.3 0.7 1.3 0.3 0.3 0.6 3.7 4.8 4.0 12.1 4.2 3.7 5.8 6.1 5.5 1.3 12.1 7.8 10.2 12.8 2.2 10.4 1.8 0.9 1.8 2.9 0.6 3.5 3.3 1.5 7.5 1.5 8.5 1.8 0.0 41.8 1.6 16.7 0.0 8.6 0.3 4.5 4.5 4.2 3.6 3.2 32.2 19.9 18.9 6.1 5.1 5.2 7.0 6.7 3.6 8.2 7.7 1.7 39.3 4.6 10.2 7.5 1.7 0.4 2.8 2.8 1.8 10.3 4.7 2.6 0.0 19.1 12.1 10.2 6.5 6.8 1.9 7.8 4.6 3.0 7.5 0.8 0.0 17.5 5.7 0.5 1.7 0.4 1.0 94.0 1.0 4.0 4.3 8.9 SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1072.1" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1578.7" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Group enriched" "Detected in some" 34 "Hep G2: 39.6;RT4: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 1200000 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" 0.1 235.6 0.3 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.5 0.6 59.5 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.2 1072.1 0.0 0.2 0.2 0.3 0.1 0.1 36.9 0.0 0.1 0.2 0.1 0.9 1.0 0.1 3.1 0.1 0.3 86.6 0.0 0.0 0.4 24.4 4.2 0.2 0.0 0.1 0.0 0.1 2.0 0.1 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 39.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 26.7 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.0 0.2 0.1 2.9 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.4 0.3 0.8 0.5 0.1 0.3 0.2 0.2 0.3 0.2 0.7 0.4 0.2 0.1 0.2 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.0 0.3 2.9 0.1 0.6 0.0 0.0 1.3 0.0 0.0 0.6 18.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 18.7 0.3 0.0 0.0 0.3 5.1 0.1 0.0 0.1 30.0 1578.7 0.0 0.0 0.3 2.8 0.0 31.8 0.4 0.2 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 8.8 0.4 0.0 0.3 171.7 0.1 0.0 2.7 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.5 1.8 81.7 2.2 0.3 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enriched" "Detected in some" 18 "Proximal tubular cells: 107.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 31.4;kidney: 21.0;liver: 13.3;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 91.5;Distal enterocytes: 89.8;Hepatocytes: 53.5;Paneth cells: 54.7;Proximal enterocytes: 248.9;Proximal tubular cells: 130.8;Undifferentiated cells: 101.1" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 59 "Hep G2: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045108 Supported NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.7 9.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 21.0 13.3 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 91.5 0.0 3.7 0.0 0.0 0.0 89.8 11.7 26.3 0.0 0.0 0.0 0.0 12.2 2.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 53.5 0.0 0.0 0.0 34.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 54.7 0.0 0.0 0.0 248.9 130.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 101.1 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 883.5" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "RH-30: 4.6" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.9 0.0 0.0 1.3 1273.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 10.7 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 11.7 883.5 0.1 0.0 0.1 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.6;Glandular and luminal cells: 234.7;Hepatocytes: 550.8;Proximal tubular cells: 1249.5" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 310.8" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.2 0.0 0.0 0.3 0.0 0.0 2.3 0.0 0.0 32.0 0.0 3.8 68.7 8.9 24.2 0.2 49.9 10.4 0.0 0.0 0.0 1299.8 1612.1 0.4 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.1 0.0 0.3 6.9 0.0 3.6 27.5 0.0 0.3 66.6 0.3 0.0 0.0 0.9 0.1 0.0 0.9 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.3 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 41.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.6 0.1 310.8 2.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 43.2 0.0 0.0 0.0 0.2 0.3 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.6 1.6 0.0 0.0 1.2 0.6 0.1 38.6 2.1 125.0 0.0 0.0 0.0 5.7 97.8 6.6 0.3 150.6 14.0 1.0 3.5 2.7 0.4 10.6 0.0 0.1 0.0 234.7 0.0 0.0 8.9 550.8 0.1 0.0 0.3 37.3 0.0 13.8 0.0 0.0 1.8 7.6 3.6 0.0 0.0 0.0 0.0 1.5 0.4 13.0 10.7 0.0 0.0 0.6 70.6 1249.5 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 6.3 0.1 5.9 2.3 WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099430-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Astrocytes: 927.8;Excitatory neurons: 270.5;Inhibitory neurons: 540.9;Microglial cells: 471.2;Oligodendrocyte precursor cells: 914.9;Oligodendrocytes: 793.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA050992: AB_2681299" "prognostic unfavorable (9.07e-5)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-2)" "unprognostic (2.32e-1)" "unprognostic (1.81e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (4.33e-2)" "unprognostic (3.50e-2)" "prognostic favorable (4.49e-5)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.77e-1)" 8.6 6.3 18.6 4.0 23.9 4.2 7.4 24.0 20.3 8.6 21.2 5.2 5.3 8.2 10.1 7.7 9.0 7.4 5.2 18.8 22.5 12.7 12.0 5.3 4.6 24.0 22.4 7.6 8.3 12.1 9.8 5.3 25.3 7.7 3.2 6.9 8.5 6.4 3.3 7.1 4.5 5.1 22.0 4.7 6.0 9.3 21.0 9.0 21.8 2.1 6.0 6.7 7.1 30.0 11.1 9.5 9.2 7.7 11.0 5.3 11.1 1.6 3.2 3.7 3.2 7.0 9.6 19.5 8.6 1.5 5.2 10.0 5.1 1.3 2.6 11.0 26.8 6.0 1.9 15.7 7.5 16.7 3.4 5.9 3.8 2.3 2.4 0.9 4.4 25.9 9.2 4.2 2.6 85.7 27.7 21.9 8.6 5.9 5.7 32.2 3.9 19.1 5.3 3.9 17.6 10.0 7.1 11.9 4.0 9.3 12.8 12.0 1.6 2.7 10.4 2.2 6.4 0.0 18.3 41.2 10.4 8.4 4.6 7.0 9.1 2.1 11.4 7.9 13.4 9.3 8.2 9.1 7.7 6.6 8.4 8.3 0.7 9.1 5.8 14.5 13.5 6.0 18.6 23.9 24.0 20.3 18.8 22.5 24.0 22.4 25.3 22.0 21.0 30.0 12.0 6.4 6.9 927.8 9.0 9.2 21.2 8.0 19.4 7.4 12.1 16.1 8.8 17.2 13.3 14.7 4.2 25.7 10.9 4.5 33.2 12.4 43.1 18.2 13.9 9.5 9.6 13.3 270.5 10.3 11.9 12.0 9.2 7.6 12.7 18.7 13.2 18.9 9.2 5.0 540.9 5.1 0.0 5.6 5.7 38.2 14.0 7.7 5.4 471.2 5.9 46.3 9.2 914.9 793.5 4.5 5.9 17.7 18.4 11.5 8.7 28.3 18.7 12.2 6.6 10.3 11.8 19.7 17.9 13.3 6.8 17.4 9.9 12.1 6.8 13.0