[{"Gene":"AACS","Gene synonym":["ACSF1","FLJ12389","SUR-5"],"Ensembl":"ENSG00000081760","Gene description":"Acetoacetyl-CoA synthetase","Uniprot":["Q86V21"],"Chromosome":"12","Position":"125065434-125143333","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"67.1","Excitatory neurons":"59.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058815"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA058815":"AB_2683826"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.7","Tissue RNA - adrenal gland [nTPM]":"7.8","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"43.4","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"14.6","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"17.9","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"30.9","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"6.1","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"48.2","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"40.4","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"16.9","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"10.4","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"6.1","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"26.8","Cell RNA - A549 [nTPM]":"26.2","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"15.3","Cell RNA - ASC diff [nTPM]":"40.3","Cell RNA - ASC TERT1 [nTPM]":"26.1","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"34.0","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"16.5","Cell RNA - EFO-21 [nTPM]":"21.3","Cell RNA - fHDF\/TERT166 [nTPM]":"25.7","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"28.4","Cell RNA - HAP1 [nTPM]":"21.0","Cell RNA - HBEC3-KT [nTPM]":"22.8","Cell RNA - HBF TERT88 [nTPM]":"13.2","Cell RNA - HDLM-2 [nTPM]":"17.8","Cell RNA - HEK 293 [nTPM]":"19.2","Cell RNA - HEL [nTPM]":"13.1","Cell RNA - HeLa [nTPM]":"16.9","Cell RNA - Hep G2 [nTPM]":"26.2","Cell RNA - HHSteC [nTPM]":"33.5","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"29.1","Cell RNA - hTCEpi [nTPM]":"18.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.0","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"30.8","Cell RNA - HUVEC TERT2 [nTPM]":"18.1","Cell RNA - JURKAT [nTPM]":"9.5","Cell RNA - K-562 [nTPM]":"9.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"15.9","Cell RNA - MCF7 [nTPM]":"49.1","Cell RNA - MOLT-4 [nTPM]":"10.8","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"14.2","Cell RNA - OE19 [nTPM]":"28.0","Cell RNA - PC-3 [nTPM]":"30.4","Cell RNA - REH [nTPM]":"2.1","Cell RNA - RH-30 [nTPM]":"28.2","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"40.2","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"8.6","Cell RNA - SiHa [nTPM]":"22.4","Cell RNA - SK-BR-3 [nTPM]":"35.0","Cell RNA - SK-MEL-30 [nTPM]":"16.6","Cell RNA - SuSa [nTPM]":"10.8","Cell RNA - T-47d [nTPM]":"26.2","Cell RNA - THP-1 [nTPM]":"20.7","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"11.8","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"13.4","Cell RNA - U-251 MG [nTPM]":"16.4","Cell RNA - U-266\/70 [nTPM]":"22.0","Cell RNA - U-266\/84 [nTPM]":"13.6","Cell RNA - U-698 [nTPM]":"18.0","Cell RNA - U-87 MG [nTPM]":"14.8","Cell RNA - U-937 [nTPM]":"15.4","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"5.4","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"9.9","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.3","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"4.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"12.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.0","Single Cell Type RNA - Early spermatids [nTPM]":"67.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"22.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"5.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"22.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"20.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"ACAT2","Gene synonym":[],"Ensembl":"ENSG00000120437","Gene description":"Acetyl-CoA acetyltransferase 2","Uniprot":["Q9BWD1"],"Chromosome":"6","Position":"159762045-159779112","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"231.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"262.1","Early spermatids":"187.0","Exocrine glandular cells":"176.6","Hepatocytes":"214.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021106","HPA025736","HPA025765","HPA025811"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB021106":"AB_10058215","HPA025736":"AB_1844487","HPA025765":"AB_1844485","HPA025811":"AB_1844488"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"21.6","Tissue RNA - amygdala [nTPM]":"22.2","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"24.4","Tissue RNA - bone marrow [nTPM]":"22.4","Tissue RNA - breast [nTPM]":"23.6","Tissue RNA - cerebellum [nTPM]":"30.2","Tissue RNA - cerebral cortex [nTPM]":"30.0","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"20.1","Tissue RNA - colon [nTPM]":"38.5","Tissue RNA - duodenum [nTPM]":"31.2","Tissue RNA - endometrium 1 [nTPM]":"10.9","Tissue RNA - epididymis [nTPM]":"40.0","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"22.7","Tissue RNA - hypothalamus [nTPM]":"27.6","Tissue RNA - kidney [nTPM]":"27.0","Tissue RNA - liver [nTPM]":"231.3","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"25.0","Tissue RNA - medulla oblongata [nTPM]":"39.4","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"17.3","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"12.5","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"39.1","Tissue RNA - prostate [nTPM]":"35.6","Tissue RNA - rectum [nTPM]":"33.8","Tissue RNA - retina [nTPM]":"19.5","Tissue RNA - salivary gland [nTPM]":"15.5","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"18.1","Tissue RNA - small intestine [nTPM]":"17.9","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"24.8","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"28.6","Tissue RNA - thalamus [nTPM]":"24.4","Tissue RNA - thymus [nTPM]":"39.4","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"36.7","Tissue RNA - urinary bladder [nTPM]":"13.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"28.1","Cell RNA - A-431 [nTPM]":"70.1","Cell RNA - A549 [nTPM]":"58.8","Cell RNA - AF22 [nTPM]":"451.9","Cell RNA - AN3-CA [nTPM]":"160.8","Cell RNA - ASC diff [nTPM]":"57.2","Cell RNA - ASC TERT1 [nTPM]":"111.6","Cell RNA - BEWO [nTPM]":"14.4","Cell RNA - BJ [nTPM]":"57.4","Cell RNA - BJ hTERT+ [nTPM]":"70.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"141.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"244.5","Cell RNA - CACO-2 [nTPM]":"234.0","Cell RNA - CAPAN-2 [nTPM]":"87.1","Cell RNA - Daudi [nTPM]":"55.9","Cell RNA - EFO-21 [nTPM]":"29.0","Cell RNA - fHDF\/TERT166 [nTPM]":"48.7","Cell RNA - GAMG [nTPM]":"458.2","Cell RNA - HaCaT [nTPM]":"64.5","Cell RNA - HAP1 [nTPM]":"174.8","Cell RNA - HBEC3-KT [nTPM]":"465.8","Cell RNA - HBF TERT88 [nTPM]":"166.7","Cell RNA - HDLM-2 [nTPM]":"35.2","Cell RNA - HEK 293 [nTPM]":"174.4","Cell RNA - HEL [nTPM]":"127.4","Cell RNA - HeLa [nTPM]":"97.2","Cell RNA - Hep G2 [nTPM]":"418.8","Cell RNA - HHSteC [nTPM]":"62.0","Cell RNA - HL-60 [nTPM]":"81.4","Cell RNA - HMC-1 [nTPM]":"35.8","Cell RNA - HSkMC [nTPM]":"62.2","Cell RNA - hTCEpi [nTPM]":"40.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"231.1","Cell RNA - hTERT-HME1 [nTPM]":"92.9","Cell RNA - hTERT-RPE1 [nTPM]":"21.4","Cell RNA - HUVEC TERT2 [nTPM]":"68.8","Cell RNA - JURKAT [nTPM]":"160.1","Cell RNA - K-562 [nTPM]":"139.9","Cell RNA - Karpas-707 [nTPM]":"104.3","Cell RNA - LHCN-M2 [nTPM]":"85.5","Cell RNA - MCF7 [nTPM]":"113.0","Cell RNA - MOLT-4 [nTPM]":"137.0","Cell RNA - NB-4 [nTPM]":"154.0","Cell RNA - NTERA-2 [nTPM]":"142.8","Cell RNA - OE19 [nTPM]":"65.5","Cell RNA - PC-3 [nTPM]":"41.7","Cell RNA - REH [nTPM]":"83.9","Cell RNA - RH-30 [nTPM]":"94.4","Cell RNA - RPMI-8226 [nTPM]":"173.1","Cell RNA - RPTEC TERT1 [nTPM]":"377.2","Cell RNA - RT4 [nTPM]":"93.7","Cell RNA - SCLC-21H [nTPM]":"107.8","Cell RNA - SH-SY5Y [nTPM]":"63.2","Cell RNA - SiHa [nTPM]":"67.5","Cell RNA - SK-BR-3 [nTPM]":"43.3","Cell RNA - SK-MEL-30 [nTPM]":"26.2","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"83.4","Cell RNA - THP-1 [nTPM]":"157.3","Cell RNA - TIME [nTPM]":"39.2","Cell RNA - U-138 MG [nTPM]":"50.3","Cell RNA - U-2 OS [nTPM]":"45.7","Cell RNA - U-2197 [nTPM]":"72.1","Cell RNA - U-251 MG [nTPM]":"154.0","Cell RNA - U-266\/70 [nTPM]":"47.7","Cell RNA - U-266\/84 [nTPM]":"89.0","Cell RNA - U-698 [nTPM]":"142.0","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"151.2","Cell RNA - WM-115 [nTPM]":"77.1","Blood RNA - basophil [nTPM]":"30.1","Blood RNA - classical monocyte [nTPM]":"24.9","Blood RNA - eosinophil [nTPM]":"46.7","Blood RNA - gdT-cell [nTPM]":"47.9","Blood RNA - intermediate monocyte [nTPM]":"33.9","Blood RNA - MAIT T-cell [nTPM]":"47.3","Blood RNA - memory B-cell [nTPM]":"46.6","Blood RNA - memory CD4 T-cell [nTPM]":"54.1","Blood RNA - memory CD8 T-cell [nTPM]":"47.8","Blood RNA - myeloid DC [nTPM]":"34.7","Blood RNA - naive B-cell [nTPM]":"51.4","Blood RNA - naive CD4 T-cell [nTPM]":"53.3","Blood RNA - naive CD8 T-cell [nTPM]":"43.2","Blood RNA - neutrophil [nTPM]":"11.0","Blood RNA - NK-cell [nTPM]":"41.3","Blood RNA - non-classical monocyte [nTPM]":"23.6","Blood RNA - plasmacytoid DC [nTPM]":"30.4","Blood RNA - T-reg [nTPM]":"79.0","Blood RNA - total PBMC [nTPM]":"46.2","Brain RNA - amygdala [nTPM]":"22.2","Brain RNA - basal ganglia [nTPM]":"24.4","Brain RNA - cerebellum [nTPM]":"30.2","Brain RNA - cerebral cortex [nTPM]":"30.0","Brain RNA - hippocampal formation [nTPM]":"22.7","Brain RNA - hypothalamus [nTPM]":"27.6","Brain RNA - medulla oblongata [nTPM]":"39.4","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"39.1","Brain RNA - spinal cord [nTPM]":"24.8","Brain RNA - thalamus [nTPM]":"24.4","Brain RNA - white matter [nTPM]":"28.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.4","Single Cell Type RNA - Astrocytes [nTPM]":"15.3","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"19.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"115.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"53.7","Single Cell Type RNA - dendritic cells [nTPM]":"28.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"78.8","Single Cell Type RNA - Early spermatids [nTPM]":"187.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.2","Single Cell Type RNA - Erythroid cells [nTPM]":"38.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"176.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"97.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"47.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"214.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.6","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"29.8","Single Cell Type RNA - Late spermatids [nTPM]":"128.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"25.7","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"58.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.5","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.6","Single Cell Type RNA - Paneth cells [nTPM]":"28.8","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"25.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.9","Single Cell Type RNA - Spermatocytes [nTPM]":"28.5","Single Cell Type RNA - Spermatogonia [nTPM]":"45.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - T-cells [nTPM]":"31.0","Single Cell Type RNA - Theca cells [nTPM]":"102.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.0","Single Cell Type RNA - Urothelial cells [nTPM]":"38.9"},{"Gene":"CEL","Gene synonym":["BSSL","MODY8"],"Ensembl":"ENSG00000170835","Gene description":"Carboxyl ester lipase","Uniprot":["P19835"],"Chromosome":"9","Position":"133061981-133071861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"548","RNA tissue specific nTPM":{"pancreas":"110578.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Breast glandular cells":"390.7","Exocrine glandular cells":"943.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"29","RNA cancer specific FPKM":{"pancreatic cancer":"469.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"7.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008023","HPA052701"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008023":"AB_1846509","HPA052701":"AB_2681921"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"10.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"6.4","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"21.6","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"200.8","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"57.2","Tissue RNA - pancreas [nTPM]":"110578.0","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"201.7","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"3.1","Cell RNA - AN3-CA [nTPM]":"1.9","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"7.5","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"2.7","Cell RNA - SCLC-21H [nTPM]":"5.3","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.9","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"3.4","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"390.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"943.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"CYP27A1","Gene synonym":["CP27","CTX","CYP27"],"Ensembl":"ENSG00000135929","Gene description":"Cytochrome P450 family 27 subfamily A member 1","Uniprot":["Q02318"],"Chromosome":"2","Position":"218781749-218815293","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"594.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"404.3","Hofbauer cells":"148.9","Proximal enterocytes":"206.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"176.9","melanoma":"85.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"151.5","neutrophil":"126.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"granulocytes":"126.3","monocytes":"151.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"299.6","HSkMC":"54.7","RPTEC TERT1":"78.5","SK-MEL-30":"103.6","WM-115":"42.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059155"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA059155":"AB_2683933"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.62e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"50.3","Tissue RNA - amygdala [nTPM]":"45.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"59.0","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"21.8","Tissue RNA - cerebellum [nTPM]":"57.0","Tissue RNA - cerebral cortex [nTPM]":"59.3","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"75.6","Tissue RNA - colon [nTPM]":"27.6","Tissue RNA - duodenum [nTPM]":"77.8","Tissue RNA - endometrium 1 [nTPM]":"19.8","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"11.9","Tissue RNA - fallopian tube [nTPM]":"34.0","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"30.7","Tissue RNA - hippocampal formation [nTPM]":"42.2","Tissue RNA - hypothalamus [nTPM]":"49.3","Tissue RNA - kidney [nTPM]":"46.4","Tissue RNA - liver [nTPM]":"594.4","Tissue RNA - lung [nTPM]":"71.7","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"63.0","Tissue RNA - midbrain [nTPM]":"56.1","Tissue RNA - ovary [nTPM]":"32.6","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"29.6","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"62.7","Tissue RNA - prostate [nTPM]":"41.8","Tissue RNA - rectum [nTPM]":"20.7","Tissue RNA - retina [nTPM]":"22.5","Tissue RNA - salivary gland [nTPM]":"40.4","Tissue RNA - seminal vesicle [nTPM]":"29.5","Tissue RNA - skeletal muscle [nTPM]":"37.9","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"81.9","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"50.6","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"12.6","Tissue RNA - thalamus [nTPM]":"58.8","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"12.6","Tissue RNA - tongue [nTPM]":"49.2","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"24.3","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"69.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"4.6","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.8","Cell RNA - CACO-2 [nTPM]":"13.7","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"7.6","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"299.6","Cell RNA - HHSteC [nTPM]":"16.2","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"54.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"5.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"78.5","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"103.6","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"42.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"151.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"17.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"126.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"44.1","Brain RNA - amygdala [nTPM]":"45.2","Brain RNA - basal ganglia [nTPM]":"59.0","Brain RNA - cerebellum [nTPM]":"57.0","Brain RNA - cerebral cortex [nTPM]":"59.3","Brain RNA - hippocampal formation [nTPM]":"42.2","Brain RNA - hypothalamus [nTPM]":"49.3","Brain RNA - medulla oblongata [nTPM]":"63.0","Brain RNA - midbrain [nTPM]":"56.1","Brain RNA - pons [nTPM]":"62.7","Brain RNA - spinal cord [nTPM]":"50.6","Brain RNA - thalamus [nTPM]":"58.8","Brain RNA - white matter [nTPM]":"69.2","Single Cell Type RNA - Adipocytes [nTPM]":"10.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.9","Single Cell Type RNA - Astrocytes [nTPM]":"33.6","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"12.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"404.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"148.9","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"47.5","Single Cell Type RNA - Macrophages [nTPM]":"104.3","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"92.4","Single Cell Type RNA - Muller glia cells [nTPM]":"28.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"108.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"44.0","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"206.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"76.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"CYP4F8","Gene synonym":[],"Ensembl":"ENSG00000186526","Gene description":"Cytochrome P450 family 4 subfamily F member 8","Uniprot":["P98187"],"Chromosome":"19","Position":"15615218-15630639","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"seminal vesicle":"215.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"1.2","Breast glandular cells":"1.7","granulocytes":"1.3","NK-cells":"1.0","Prostatic glandular cells":"1.3","Skeletal myocytes":"1.7","Urothelial cells":"2.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"10.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"1.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058960":"AB_2683862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-6"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"14.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"215.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"CYP51A1","Gene synonym":["CP51","CYP51","CYPL1","LDM","P450-14DM","P450L1"],"Ensembl":"ENSG00000001630","Gene description":"Cytochrome P450 family 51 subfamily A member 1","Uniprot":["Q16850"],"Chromosome":"7","Position":"92112153-92134803","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"204.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"67.3","Alveolar cells type 2":"169.7","Early spermatids":"74.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"481.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041325","HPA043508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA041325":"AB_2677411","HPA043508":"AB_2678520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.12e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.4","Tissue RNA - adrenal gland [nTPM]":"58.2","Tissue RNA - amygdala [nTPM]":"22.3","Tissue RNA - appendix [nTPM]":"20.6","Tissue RNA - basal ganglia [nTPM]":"24.9","Tissue RNA - bone marrow [nTPM]":"30.3","Tissue RNA - breast [nTPM]":"30.6","Tissue RNA - cerebellum [nTPM]":"39.8","Tissue RNA - cerebral cortex [nTPM]":"32.3","Tissue RNA - cervix [nTPM]":"26.4","Tissue RNA - choroid plexus [nTPM]":"21.0","Tissue RNA - colon [nTPM]":"52.7","Tissue RNA - duodenum [nTPM]":"86.6","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"35.8","Tissue RNA - esophagus [nTPM]":"43.7","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"24.3","Tissue RNA - heart muscle [nTPM]":"20.7","Tissue RNA - hippocampal formation [nTPM]":"24.2","Tissue RNA - hypothalamus [nTPM]":"39.0","Tissue RNA - kidney [nTPM]":"38.7","Tissue RNA - liver [nTPM]":"204.7","Tissue RNA - lung [nTPM]":"53.2","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"60.1","Tissue RNA - midbrain [nTPM]":"42.3","Tissue RNA - ovary [nTPM]":"29.0","Tissue RNA - pancreas [nTPM]":"48.7","Tissue RNA - parathyroid gland [nTPM]":"59.6","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"21.9","Tissue RNA - pons [nTPM]":"50.6","Tissue RNA - prostate [nTPM]":"43.8","Tissue RNA - rectum [nTPM]":"41.5","Tissue RNA - retina [nTPM]":"31.4","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"17.5","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"26.5","Tissue RNA - small intestine [nTPM]":"40.0","Tissue RNA - smooth muscle [nTPM]":"20.4","Tissue RNA - spinal cord [nTPM]":"46.6","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"86.4","Tissue RNA - thalamus [nTPM]":"31.8","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"33.6","Tissue RNA - tongue [nTPM]":"11.7","Tissue RNA - tonsil [nTPM]":"16.6","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"26.2","Tissue RNA - white matter [nTPM]":"57.0","Cell RNA - A-431 [nTPM]":"113.7","Cell RNA - A549 [nTPM]":"54.3","Cell RNA - AF22 [nTPM]":"134.0","Cell RNA - AN3-CA [nTPM]":"86.4","Cell RNA - ASC diff [nTPM]":"92.0","Cell RNA - ASC TERT1 [nTPM]":"149.6","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"37.7","Cell RNA - BJ hTERT+ [nTPM]":"112.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"128.8","Cell RNA - CACO-2 [nTPM]":"131.8","Cell RNA - CAPAN-2 [nTPM]":"201.7","Cell RNA - Daudi [nTPM]":"98.1","Cell RNA - EFO-21 [nTPM]":"57.9","Cell RNA - fHDF\/TERT166 [nTPM]":"65.3","Cell RNA - GAMG [nTPM]":"481.6","Cell RNA - HaCaT [nTPM]":"96.2","Cell RNA - HAP1 [nTPM]":"118.1","Cell RNA - HBEC3-KT [nTPM]":"237.0","Cell RNA - HBF TERT88 [nTPM]":"55.3","Cell RNA - HDLM-2 [nTPM]":"40.3","Cell RNA - HEK 293 [nTPM]":"82.6","Cell RNA - HEL [nTPM]":"27.9","Cell RNA - HeLa [nTPM]":"51.1","Cell RNA - Hep G2 [nTPM]":"99.7","Cell RNA - HHSteC [nTPM]":"125.7","Cell RNA - HL-60 [nTPM]":"56.0","Cell RNA - HMC-1 [nTPM]":"39.4","Cell RNA - HSkMC [nTPM]":"109.1","Cell RNA - hTCEpi [nTPM]":"105.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"185.6","Cell RNA - hTERT-HME1 [nTPM]":"194.0","Cell RNA - hTERT-RPE1 [nTPM]":"42.2","Cell RNA - HUVEC TERT2 [nTPM]":"49.4","Cell RNA - JURKAT [nTPM]":"19.8","Cell RNA - K-562 [nTPM]":"108.2","Cell RNA - Karpas-707 [nTPM]":"217.8","Cell RNA - LHCN-M2 [nTPM]":"56.4","Cell RNA - MCF7 [nTPM]":"115.6","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"53.8","Cell RNA - NTERA-2 [nTPM]":"100.7","Cell RNA - OE19 [nTPM]":"45.9","Cell RNA - PC-3 [nTPM]":"53.4","Cell RNA - REH [nTPM]":"40.3","Cell RNA - RH-30 [nTPM]":"27.8","Cell RNA - RPMI-8226 [nTPM]":"222.8","Cell RNA - RPTEC TERT1 [nTPM]":"216.7","Cell RNA - RT4 [nTPM]":"187.9","Cell RNA - SCLC-21H [nTPM]":"94.1","Cell RNA - SH-SY5Y [nTPM]":"62.5","Cell RNA - SiHa [nTPM]":"80.0","Cell RNA - SK-BR-3 [nTPM]":"156.3","Cell RNA - SK-MEL-30 [nTPM]":"117.2","Cell RNA - SuSa [nTPM]":"60.6","Cell RNA - T-47d [nTPM]":"56.9","Cell RNA - THP-1 [nTPM]":"69.5","Cell RNA - TIME [nTPM]":"59.5","Cell RNA - U-138 MG [nTPM]":"65.0","Cell RNA - U-2 OS [nTPM]":"70.6","Cell RNA - U-2197 [nTPM]":"95.2","Cell RNA - U-251 MG [nTPM]":"49.8","Cell RNA - U-266\/70 [nTPM]":"72.8","Cell RNA - U-266\/84 [nTPM]":"70.5","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"49.8","Cell RNA - U-937 [nTPM]":"75.5","Cell RNA - WM-115 [nTPM]":"85.2","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"11.1","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"16.3","Blood RNA - MAIT T-cell [nTPM]":"7.7","Blood RNA - memory B-cell [nTPM]":"15.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.0","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"16.3","Blood RNA - naive B-cell [nTPM]":"12.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.1","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"10.3","Blood RNA - plasmacytoid DC [nTPM]":"14.3","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"8.2","Brain RNA - amygdala [nTPM]":"22.3","Brain RNA - basal ganglia [nTPM]":"24.9","Brain RNA - cerebellum [nTPM]":"39.8","Brain RNA - cerebral cortex [nTPM]":"32.3","Brain RNA - hippocampal formation [nTPM]":"24.2","Brain RNA - hypothalamus [nTPM]":"39.0","Brain RNA - medulla oblongata [nTPM]":"60.1","Brain RNA - midbrain [nTPM]":"42.3","Brain RNA - pons [nTPM]":"50.6","Brain RNA - spinal cord [nTPM]":"46.6","Brain RNA - thalamus [nTPM]":"31.8","Brain RNA - white matter [nTPM]":"57.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"169.7","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"24.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"44.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"8.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"74.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.4","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"45.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"34.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.2","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"34.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.8","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"CYP7A1","Gene synonym":["CYP7"],"Ensembl":"ENSG00000167910","Gene description":"Cytochrome P450 family 7 subfamily A member 1","Uniprot":["P22680"],"Chromosome":"8","Position":"58490178-58500163","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"80","RNA tissue specific nTPM":{"liver":"49.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Hepatocytes":"7.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"28.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"49.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DHCR24","Gene synonym":["DCE","KIAA0018","seladin-1"],"Ensembl":"ENSG00000116133","Gene description":"24-dehydrocholesterol reductase","Uniprot":["Q15392"],"Chromosome":"1","Position":"54849627-54887195","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1129.5","liver":"623.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"298.1","Alveolar cells type 2":"682.3","Hepatocytes":"1091.4","Theca cells":"442.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1031.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017981","CAB037247","HPA063005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037247":"AB_796187","HPA017981":"AB_2732422","HPA063005":"AB_2684919"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"58.3","Tissue RNA - adrenal gland [nTPM]":"1129.5","Tissue RNA - amygdala [nTPM]":"35.7","Tissue RNA - appendix [nTPM]":"19.8","Tissue RNA - basal ganglia [nTPM]":"58.5","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"104.8","Tissue RNA - cerebellum [nTPM]":"125.3","Tissue RNA - cerebral cortex [nTPM]":"73.0","Tissue RNA - cervix [nTPM]":"54.9","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"55.6","Tissue RNA - duodenum [nTPM]":"62.2","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"296.1","Tissue RNA - fallopian tube [nTPM]":"60.4","Tissue RNA - gallbladder [nTPM]":"42.2","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"55.9","Tissue RNA - hypothalamus [nTPM]":"63.9","Tissue RNA - kidney [nTPM]":"48.6","Tissue RNA - liver [nTPM]":"623.5","Tissue RNA - lung [nTPM]":"215.9","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"216.2","Tissue RNA - midbrain [nTPM]":"91.3","Tissue RNA - ovary [nTPM]":"28.5","Tissue RNA - pancreas [nTPM]":"30.5","Tissue RNA - parathyroid gland [nTPM]":"157.9","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"21.6","Tissue RNA - pons [nTPM]":"158.9","Tissue RNA - prostate [nTPM]":"128.6","Tissue RNA - rectum [nTPM]":"40.5","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"136.2","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"197.7","Tissue RNA - skin 1 [nTPM]":"247.6","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"12.6","Tissue RNA - spinal cord [nTPM]":"129.3","Tissue RNA - spleen [nTPM]":"134.1","Tissue RNA - stomach 1 [nTPM]":"98.9","Tissue RNA - testis [nTPM]":"74.2","Tissue RNA - thalamus [nTPM]":"87.9","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"11.1","Tissue RNA - tonsil [nTPM]":"33.9","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"103.9","Tissue RNA - white matter [nTPM]":"280.7","Cell RNA - A-431 [nTPM]":"342.1","Cell RNA - A549 [nTPM]":"58.5","Cell RNA - AF22 [nTPM]":"210.6","Cell RNA - AN3-CA [nTPM]":"257.1","Cell RNA - ASC diff [nTPM]":"1031.9","Cell RNA - ASC TERT1 [nTPM]":"219.0","Cell RNA - BEWO [nTPM]":"50.5","Cell RNA - BJ [nTPM]":"94.8","Cell RNA - BJ hTERT+ [nTPM]":"160.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"130.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"268.6","Cell RNA - CACO-2 [nTPM]":"341.6","Cell RNA - CAPAN-2 [nTPM]":"210.2","Cell RNA - Daudi [nTPM]":"55.3","Cell RNA - EFO-21 [nTPM]":"191.5","Cell RNA - fHDF\/TERT166 [nTPM]":"82.4","Cell RNA - GAMG [nTPM]":"427.4","Cell RNA - HaCaT [nTPM]":"319.2","Cell RNA - HAP1 [nTPM]":"250.5","Cell RNA - HBEC3-KT [nTPM]":"501.3","Cell RNA - HBF TERT88 [nTPM]":"118.3","Cell RNA - HDLM-2 [nTPM]":"8.3","Cell RNA - HEK 293 [nTPM]":"159.6","Cell RNA - HEL [nTPM]":"303.3","Cell RNA - HeLa [nTPM]":"131.8","Cell RNA - Hep G2 [nTPM]":"421.7","Cell RNA - HHSteC [nTPM]":"168.9","Cell RNA - HL-60 [nTPM]":"126.7","Cell RNA - HMC-1 [nTPM]":"68.2","Cell RNA - HSkMC [nTPM]":"161.0","Cell RNA - hTCEpi [nTPM]":"429.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"397.6","Cell RNA - hTERT-HME1 [nTPM]":"74.7","Cell RNA - hTERT-RPE1 [nTPM]":"66.7","Cell RNA - HUVEC TERT2 [nTPM]":"67.2","Cell RNA - JURKAT [nTPM]":"124.5","Cell RNA - K-562 [nTPM]":"224.7","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"50.2","Cell RNA - MCF7 [nTPM]":"143.5","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"111.4","Cell RNA - NTERA-2 [nTPM]":"592.0","Cell RNA - OE19 [nTPM]":"90.7","Cell RNA - PC-3 [nTPM]":"164.2","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"54.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"735.3","Cell RNA - RT4 [nTPM]":"257.1","Cell RNA - SCLC-21H [nTPM]":"144.5","Cell RNA - SH-SY5Y [nTPM]":"53.2","Cell RNA - SiHa [nTPM]":"185.0","Cell RNA - SK-BR-3 [nTPM]":"337.5","Cell RNA - SK-MEL-30 [nTPM]":"123.1","Cell RNA - SuSa [nTPM]":"221.6","Cell RNA - T-47d [nTPM]":"441.5","Cell RNA - THP-1 [nTPM]":"143.3","Cell RNA - TIME [nTPM]":"62.2","Cell RNA - U-138 MG [nTPM]":"45.3","Cell RNA - U-2 OS [nTPM]":"130.0","Cell RNA - U-2197 [nTPM]":"66.1","Cell RNA - U-251 MG [nTPM]":"183.9","Cell RNA - U-266\/70 [nTPM]":"22.7","Cell RNA - U-266\/84 [nTPM]":"55.0","Cell RNA - U-698 [nTPM]":"91.2","Cell RNA - U-87 MG [nTPM]":"32.8","Cell RNA - U-937 [nTPM]":"215.3","Cell RNA - WM-115 [nTPM]":"60.4","Blood RNA - basophil [nTPM]":"5.1","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"1.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"35.7","Brain RNA - basal ganglia [nTPM]":"58.5","Brain RNA - cerebellum [nTPM]":"125.3","Brain RNA - cerebral cortex [nTPM]":"73.0","Brain RNA - hippocampal formation [nTPM]":"55.9","Brain RNA - hypothalamus [nTPM]":"63.9","Brain RNA - medulla oblongata [nTPM]":"216.2","Brain RNA - midbrain [nTPM]":"91.3","Brain RNA - pons [nTPM]":"158.9","Brain RNA - spinal cord [nTPM]":"129.3","Brain RNA - thalamus [nTPM]":"87.9","Brain RNA - white matter [nTPM]":"280.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"298.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"682.3","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"150.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"79.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"145.8","Single Cell Type RNA - Club cells [nTPM]":"205.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"55.3","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.0","Single Cell Type RNA - Erythroid cells [nTPM]":"71.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"76.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.7","Single Cell Type RNA - granulocytes [nTPM]":"32.2","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"111.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1091.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.2","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"68.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"77.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"6.8","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.6","Single Cell Type RNA - Paneth cells [nTPM]":"27.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"136.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"145.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"442.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.2","Single Cell Type RNA - Urothelial cells [nTPM]":"45.2"},{"Gene":"DHCR7","Gene synonym":["SLOS"],"Ensembl":"ENSG00000172893","Gene description":"7-dehydrocholesterol reductase","Uniprot":["Q9UBM7"],"Chromosome":"11","Position":"71428193-71452868","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"161.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"77.9","Granulosa cells":"81.3","Hepatocytes":"156.1","Theca cells":"103.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044280"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044280":"AB_10794893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"97.2","Tissue RNA - amygdala [nTPM]":"28.1","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"35.4","Tissue RNA - bone marrow [nTPM]":"46.7","Tissue RNA - breast [nTPM]":"36.3","Tissue RNA - cerebellum [nTPM]":"42.4","Tissue RNA - cerebral cortex [nTPM]":"37.0","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"21.1","Tissue RNA - duodenum [nTPM]":"48.1","Tissue RNA - endometrium 1 [nTPM]":"10.6","Tissue RNA - epididymis [nTPM]":"59.2","Tissue RNA - esophagus [nTPM]":"42.2","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"8.9","Tissue RNA - heart muscle [nTPM]":"28.8","Tissue RNA - hippocampal formation [nTPM]":"28.8","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"161.1","Tissue RNA - lung [nTPM]":"21.8","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"55.3","Tissue RNA - midbrain [nTPM]":"38.8","Tissue RNA - ovary [nTPM]":"54.4","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"24.4","Tissue RNA - pituitary gland [nTPM]":"18.4","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"55.8","Tissue RNA - prostate [nTPM]":"21.6","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"13.6","Tissue RNA - skin 1 [nTPM]":"68.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"34.4","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"31.0","Tissue RNA - thalamus [nTPM]":"38.0","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"9.4","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"22.7","Tissue RNA - white matter [nTPM]":"58.9","Cell RNA - A-431 [nTPM]":"126.4","Cell RNA - A549 [nTPM]":"112.3","Cell RNA - AF22 [nTPM]":"106.7","Cell RNA - AN3-CA [nTPM]":"118.9","Cell RNA - ASC diff [nTPM]":"49.0","Cell RNA - ASC TERT1 [nTPM]":"75.8","Cell RNA - BEWO [nTPM]":"33.7","Cell RNA - BJ [nTPM]":"50.9","Cell RNA - BJ hTERT+ [nTPM]":"134.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"114.5","Cell RNA - CACO-2 [nTPM]":"419.8","Cell RNA - CAPAN-2 [nTPM]":"401.5","Cell RNA - Daudi [nTPM]":"87.1","Cell RNA - EFO-21 [nTPM]":"79.0","Cell RNA - fHDF\/TERT166 [nTPM]":"48.6","Cell RNA - GAMG [nTPM]":"376.2","Cell RNA - HaCaT [nTPM]":"235.9","Cell RNA - HAP1 [nTPM]":"128.8","Cell RNA - HBEC3-KT [nTPM]":"276.7","Cell RNA - HBF TERT88 [nTPM]":"44.5","Cell RNA - HDLM-2 [nTPM]":"33.5","Cell RNA - HEK 293 [nTPM]":"98.7","Cell RNA - HEL [nTPM]":"33.4","Cell RNA - HeLa [nTPM]":"89.3","Cell RNA - Hep G2 [nTPM]":"183.1","Cell RNA - HHSteC [nTPM]":"127.8","Cell RNA - HL-60 [nTPM]":"63.7","Cell RNA - HMC-1 [nTPM]":"15.6","Cell RNA - HSkMC [nTPM]":"89.2","Cell RNA - hTCEpi [nTPM]":"122.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"159.3","Cell RNA - hTERT-HME1 [nTPM]":"108.4","Cell RNA - hTERT-RPE1 [nTPM]":"34.6","Cell RNA - HUVEC TERT2 [nTPM]":"63.8","Cell RNA - JURKAT [nTPM]":"112.7","Cell RNA - K-562 [nTPM]":"159.6","Cell RNA - Karpas-707 [nTPM]":"180.7","Cell RNA - LHCN-M2 [nTPM]":"43.2","Cell RNA - MCF7 [nTPM]":"341.1","Cell RNA - MOLT-4 [nTPM]":"52.4","Cell RNA - NB-4 [nTPM]":"72.6","Cell RNA - NTERA-2 [nTPM]":"154.1","Cell RNA - OE19 [nTPM]":"124.9","Cell RNA - PC-3 [nTPM]":"67.4","Cell RNA - REH [nTPM]":"46.9","Cell RNA - RH-30 [nTPM]":"150.6","Cell RNA - RPMI-8226 [nTPM]":"377.3","Cell RNA - RPTEC TERT1 [nTPM]":"162.3","Cell RNA - RT4 [nTPM]":"187.3","Cell RNA - SCLC-21H [nTPM]":"144.7","Cell RNA - SH-SY5Y [nTPM]":"53.9","Cell RNA - SiHa [nTPM]":"48.4","Cell RNA - SK-BR-3 [nTPM]":"157.6","Cell RNA - SK-MEL-30 [nTPM]":"113.9","Cell RNA - SuSa [nTPM]":"51.4","Cell RNA - T-47d [nTPM]":"153.2","Cell RNA - THP-1 [nTPM]":"34.5","Cell RNA - TIME [nTPM]":"60.4","Cell RNA - U-138 MG [nTPM]":"11.5","Cell RNA - U-2 OS [nTPM]":"62.4","Cell RNA - U-2197 [nTPM]":"3.7","Cell RNA - U-251 MG [nTPM]":"61.5","Cell RNA - U-266\/70 [nTPM]":"59.3","Cell RNA - U-266\/84 [nTPM]":"78.7","Cell RNA - U-698 [nTPM]":"95.8","Cell RNA - U-87 MG [nTPM]":"33.8","Cell RNA - U-937 [nTPM]":"110.9","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"10.5","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"9.8","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"11.0","Blood RNA - naive CD8 T-cell [nTPM]":"13.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"7.1","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"28.1","Brain RNA - basal ganglia [nTPM]":"35.4","Brain RNA - cerebellum [nTPM]":"42.4","Brain RNA - cerebral cortex [nTPM]":"37.0","Brain RNA - hippocampal formation [nTPM]":"28.8","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"55.3","Brain RNA - midbrain [nTPM]":"38.8","Brain RNA - pons [nTPM]":"55.8","Brain RNA - spinal cord [nTPM]":"34.4","Brain RNA - thalamus [nTPM]":"38.0","Brain RNA - white matter [nTPM]":"58.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"77.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"39.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"11.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"81.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"156.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.8","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.2","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"103.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"EBP","Gene synonym":["CDPX2","CHO2","CPX","CPXD"],"Ensembl":"ENSG00000147155","Gene description":"EBP cholestenol delta-isomerase","Uniprot":["Q15125"],"Chromosome":"X","Position":"48521799-48528716","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Dwarfism","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"328.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"674.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003130":"AB_1078717"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"73.3","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"48.3","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"17.8","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"22.0","Tissue RNA - colon [nTPM]":"50.6","Tissue RNA - duodenum [nTPM]":"85.5","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"41.3","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"32.5","Tissue RNA - hippocampal formation [nTPM]":"16.8","Tissue RNA - hypothalamus [nTPM]":"18.7","Tissue RNA - kidney [nTPM]":"44.0","Tissue RNA - liver [nTPM]":"328.5","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"24.4","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"44.0","Tissue RNA - pituitary gland [nTPM]":"7.2","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"24.2","Tissue RNA - prostate [nTPM]":"40.6","Tissue RNA - rectum [nTPM]":"57.5","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"25.0","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"9.5","Tissue RNA - skin 1 [nTPM]":"27.8","Tissue RNA - small intestine [nTPM]":"54.2","Tissue RNA - smooth muscle [nTPM]":"14.9","Tissue RNA - spinal cord [nTPM]":"15.8","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"31.6","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"28.2","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"32.7","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"23.3","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"224.5","Cell RNA - A549 [nTPM]":"96.4","Cell RNA - AF22 [nTPM]":"107.4","Cell RNA - AN3-CA [nTPM]":"77.0","Cell RNA - ASC diff [nTPM]":"74.5","Cell RNA - ASC TERT1 [nTPM]":"39.2","Cell RNA - BEWO [nTPM]":"50.5","Cell RNA - BJ [nTPM]":"48.2","Cell RNA - BJ hTERT+ [nTPM]":"43.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.9","Cell RNA - CACO-2 [nTPM]":"169.9","Cell RNA - CAPAN-2 [nTPM]":"382.7","Cell RNA - Daudi [nTPM]":"115.9","Cell RNA - EFO-21 [nTPM]":"35.2","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"83.5","Cell RNA - HaCaT [nTPM]":"230.3","Cell RNA - HAP1 [nTPM]":"217.5","Cell RNA - HBEC3-KT [nTPM]":"293.8","Cell RNA - HBF TERT88 [nTPM]":"49.8","Cell RNA - HDLM-2 [nTPM]":"85.8","Cell RNA - HEK 293 [nTPM]":"149.7","Cell RNA - HEL [nTPM]":"50.1","Cell RNA - HeLa [nTPM]":"115.2","Cell RNA - Hep G2 [nTPM]":"139.3","Cell RNA - HHSteC [nTPM]":"57.8","Cell RNA - HL-60 [nTPM]":"179.2","Cell RNA - HMC-1 [nTPM]":"138.2","Cell RNA - HSkMC [nTPM]":"51.3","Cell RNA - hTCEpi [nTPM]":"108.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.9","Cell RNA - hTERT-HME1 [nTPM]":"86.4","Cell RNA - hTERT-RPE1 [nTPM]":"22.5","Cell RNA - HUVEC TERT2 [nTPM]":"46.5","Cell RNA - JURKAT [nTPM]":"98.1","Cell RNA - K-562 [nTPM]":"77.6","Cell RNA - Karpas-707 [nTPM]":"119.5","Cell RNA - LHCN-M2 [nTPM]":"50.7","Cell RNA - MCF7 [nTPM]":"163.7","Cell RNA - MOLT-4 [nTPM]":"119.1","Cell RNA - NB-4 [nTPM]":"199.9","Cell RNA - NTERA-2 [nTPM]":"118.2","Cell RNA - OE19 [nTPM]":"88.3","Cell RNA - PC-3 [nTPM]":"199.1","Cell RNA - REH [nTPM]":"93.8","Cell RNA - RH-30 [nTPM]":"10.3","Cell RNA - RPMI-8226 [nTPM]":"363.7","Cell RNA - RPTEC TERT1 [nTPM]":"175.6","Cell RNA - RT4 [nTPM]":"68.8","Cell RNA - SCLC-21H [nTPM]":"110.0","Cell RNA - SH-SY5Y [nTPM]":"59.6","Cell RNA - SiHa [nTPM]":"175.4","Cell RNA - SK-BR-3 [nTPM]":"122.6","Cell RNA - SK-MEL-30 [nTPM]":"31.2","Cell RNA - SuSa [nTPM]":"91.5","Cell RNA - T-47d [nTPM]":"122.9","Cell RNA - THP-1 [nTPM]":"71.1","Cell RNA - TIME [nTPM]":"46.6","Cell RNA - U-138 MG [nTPM]":"33.1","Cell RNA - U-2 OS [nTPM]":"56.2","Cell RNA - U-2197 [nTPM]":"132.9","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"47.5","Cell RNA - U-266\/84 [nTPM]":"72.1","Cell RNA - U-698 [nTPM]":"107.7","Cell RNA - U-87 MG [nTPM]":"78.7","Cell RNA - U-937 [nTPM]":"239.7","Cell RNA - WM-115 [nTPM]":"40.6","Blood RNA - basophil [nTPM]":"96.1","Blood RNA - classical monocyte [nTPM]":"37.7","Blood RNA - eosinophil [nTPM]":"97.1","Blood RNA - gdT-cell [nTPM]":"129.4","Blood RNA - intermediate monocyte [nTPM]":"53.4","Blood RNA - MAIT T-cell [nTPM]":"104.5","Blood RNA - memory B-cell [nTPM]":"71.5","Blood RNA - memory CD4 T-cell [nTPM]":"90.5","Blood RNA - memory CD8 T-cell [nTPM]":"116.7","Blood RNA - myeloid DC [nTPM]":"53.5","Blood RNA - naive B-cell [nTPM]":"57.2","Blood RNA - naive CD4 T-cell [nTPM]":"76.5","Blood RNA - naive CD8 T-cell [nTPM]":"99.7","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"63.9","Blood RNA - non-classical monocyte [nTPM]":"57.2","Blood RNA - plasmacytoid DC [nTPM]":"105.4","Blood RNA - T-reg [nTPM]":"103.1","Blood RNA - total PBMC [nTPM]":"93.6","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"17.8","Brain RNA - hippocampal formation [nTPM]":"16.8","Brain RNA - hypothalamus [nTPM]":"18.7","Brain RNA - medulla oblongata [nTPM]":"24.4","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"24.2","Brain RNA - spinal cord [nTPM]":"15.8","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"15.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"38.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"245.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"23.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"57.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"77.2","Single Cell Type RNA - Club cells [nTPM]":"116.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.9","Single Cell Type RNA - dendritic cells [nTPM]":"74.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"140.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"91.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.7","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"48.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"239.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"113.0","Single Cell Type RNA - Fibroblasts [nTPM]":"21.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.5","Single Cell Type RNA - granulocytes [nTPM]":"40.6","Single Cell Type RNA - Granulosa cells [nTPM]":"41.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"674.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"65.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.8","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"30.2","Single Cell Type RNA - Langerhans cells [nTPM]":"36.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"31.9","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"34.8","Single Cell Type RNA - Muller glia cells [nTPM]":"19.3","Single Cell Type RNA - NK-cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"156.7","Single Cell Type RNA - Paneth cells [nTPM]":"137.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"54.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"171.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"99.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"22.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - T-cells [nTPM]":"57.1","Single Cell Type RNA - Theca cells [nTPM]":"128.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"149.1","Single Cell Type RNA - Urothelial cells [nTPM]":"71.1"},{"Gene":"FDFT1","Gene synonym":["SQS"],"Ensembl":"ENSG00000079459","Gene description":"Farnesyl-diphosphate farnesyltransferase 1","Uniprot":["P37268"],"Chromosome":"8","Position":"11795573-11839304","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"479.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Daudi":"133.1","RPMI-8226":"361.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008874"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA008874":"AB_1078844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"69.1","Tissue RNA - adrenal gland [nTPM]":"126.7","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"15.0","Tissue RNA - breast [nTPM]":"69.5","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"11.6","Tissue RNA - cervix [nTPM]":"93.3","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"113.4","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"80.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"165.7","Tissue RNA - fallopian tube [nTPM]":"59.4","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"62.9","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"71.3","Tissue RNA - liver [nTPM]":"118.3","Tissue RNA - lung [nTPM]":"88.0","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"29.9","Tissue RNA - midbrain [nTPM]":"14.1","Tissue RNA - ovary [nTPM]":"66.9","Tissue RNA - pancreas [nTPM]":"58.6","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"51.2","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"23.1","Tissue RNA - prostate [nTPM]":"64.5","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"141.7","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"160.3","Tissue RNA - skin 1 [nTPM]":"129.0","Tissue RNA - small intestine [nTPM]":"92.2","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"15.4","Tissue RNA - spleen [nTPM]":"50.4","Tissue RNA - stomach 1 [nTPM]":"113.2","Tissue RNA - testis [nTPM]":"118.7","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"4.5","Tissue RNA - urinary bladder [nTPM]":"70.4","Tissue RNA - vagina [nTPM]":"107.8","Tissue RNA - white matter [nTPM]":"31.9","Cell RNA - A-431 [nTPM]":"19.1","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"28.8","Cell RNA - AN3-CA [nTPM]":"19.4","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"5.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.6","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"133.1","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.2","Cell RNA - GAMG [nTPM]":"34.6","Cell RNA - HaCaT [nTPM]":"17.8","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"24.7","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"17.2","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"21.7","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"6.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.2","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"2.1","Cell RNA - JURKAT [nTPM]":"24.5","Cell RNA - K-562 [nTPM]":"12.1","Cell RNA - Karpas-707 [nTPM]":"60.0","Cell RNA - LHCN-M2 [nTPM]":"4.6","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"16.7","Cell RNA - NB-4 [nTPM]":"12.9","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"11.3","Cell RNA - RPMI-8226 [nTPM]":"361.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.9","Cell RNA - RT4 [nTPM]":"61.5","Cell RNA - SCLC-21H [nTPM]":"9.6","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"4.3","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"35.9","Cell RNA - SuSa [nTPM]":"12.3","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"6.8","Cell RNA - TIME [nTPM]":"11.3","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"21.6","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"5.8","Cell RNA - U-266\/70 [nTPM]":"17.0","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"26.3","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"18.7","Cell RNA - WM-115 [nTPM]":"19.7","Blood RNA - basophil [nTPM]":"52.1","Blood RNA - classical monocyte [nTPM]":"19.5","Blood RNA - eosinophil [nTPM]":"25.5","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"23.6","Blood RNA - MAIT T-cell [nTPM]":"20.7","Blood RNA - memory B-cell [nTPM]":"60.5","Blood RNA - memory CD4 T-cell [nTPM]":"25.3","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"29.1","Blood RNA - naive B-cell [nTPM]":"45.6","Blood RNA - naive CD4 T-cell [nTPM]":"25.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.3","Blood RNA - neutrophil [nTPM]":"22.3","Blood RNA - NK-cell [nTPM]":"26.7","Blood RNA - non-classical monocyte [nTPM]":"15.1","Blood RNA - plasmacytoid DC [nTPM]":"27.9","Blood RNA - T-reg [nTPM]":"45.7","Blood RNA - total PBMC [nTPM]":"43.9","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"11.6","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"29.9","Brain RNA - midbrain [nTPM]":"14.1","Brain RNA - pons [nTPM]":"23.1","Brain RNA - spinal cord [nTPM]":"15.4","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"31.9","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"164.1","Single Cell Type RNA - Astrocytes [nTPM]":"67.6","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"94.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"479.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"87.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"79.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"78.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"325.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"266.2","Single Cell Type RNA - dendritic cells [nTPM]":"49.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"134.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"165.6","Single Cell Type RNA - Early spermatids [nTPM]":"294.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"45.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"79.1","Single Cell Type RNA - Erythroid cells [nTPM]":"113.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"284.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"153.3","Single Cell Type RNA - Fibroblasts [nTPM]":"37.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.1","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"86.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"221.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"94.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"117.4","Single Cell Type RNA - Ionocytes [nTPM]":"284.8","Single Cell Type RNA - Kupffer cells [nTPM]":"41.9","Single Cell Type RNA - Langerhans cells [nTPM]":"32.2","Single Cell Type RNA - Late spermatids [nTPM]":"228.8","Single Cell Type RNA - Leydig cells [nTPM]":"77.0","Single Cell Type RNA - Macrophages [nTPM]":"54.3","Single Cell Type RNA - Melanocytes [nTPM]":"101.4","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"97.1","Single Cell Type RNA - Muller glia cells [nTPM]":"61.9","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"163.6","Single Cell Type RNA - Paneth cells [nTPM]":"108.4","Single Cell Type RNA - Peritubular cells [nTPM]":"53.4","Single Cell Type RNA - Plasma cells [nTPM]":"50.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"101.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"87.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"142.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"74.4","Single Cell Type RNA - Spermatocytes [nTPM]":"215.5","Single Cell Type RNA - Spermatogonia [nTPM]":"76.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"112.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"175.0","Single Cell Type RNA - T-cells [nTPM]":"55.7","Single Cell Type RNA - Theca cells [nTPM]":"131.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"100.4","Single Cell Type RNA - Urothelial cells [nTPM]":"167.2"},{"Gene":"FDPS","Gene synonym":[],"Ensembl":"ENSG00000160752","Gene description":"Farnesyl diphosphate synthase","Uniprot":["P14324"],"Chromosome":"1","Position":"155308748-155320666","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Host-virus interaction","Isoprene biosynthesis","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"355.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"927.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"1187.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA028200":"AB_10612109"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"73.5","Tissue RNA - adrenal gland [nTPM]":"188.2","Tissue RNA - amygdala [nTPM]":"48.2","Tissue RNA - appendix [nTPM]":"66.5","Tissue RNA - basal ganglia [nTPM]":"50.4","Tissue RNA - bone marrow [nTPM]":"69.5","Tissue RNA - breast [nTPM]":"68.8","Tissue RNA - cerebellum [nTPM]":"60.1","Tissue RNA - cerebral cortex [nTPM]":"58.8","Tissue RNA - cervix [nTPM]":"63.4","Tissue RNA - choroid plexus [nTPM]":"51.1","Tissue RNA - colon [nTPM]":"88.7","Tissue RNA - duodenum [nTPM]":"167.2","Tissue RNA - endometrium 1 [nTPM]":"57.5","Tissue RNA - epididymis [nTPM]":"73.0","Tissue RNA - esophagus [nTPM]":"142.5","Tissue RNA - fallopian tube [nTPM]":"57.4","Tissue RNA - gallbladder [nTPM]":"39.8","Tissue RNA - heart muscle [nTPM]":"72.2","Tissue RNA - hippocampal formation [nTPM]":"49.9","Tissue RNA - hypothalamus [nTPM]":"64.6","Tissue RNA - kidney [nTPM]":"78.0","Tissue RNA - liver [nTPM]":"355.7","Tissue RNA - lung [nTPM]":"86.1","Tissue RNA - lymph node [nTPM]":"76.1","Tissue RNA - medulla oblongata [nTPM]":"71.1","Tissue RNA - midbrain [nTPM]":"62.5","Tissue RNA - ovary [nTPM]":"45.0","Tissue RNA - pancreas [nTPM]":"75.7","Tissue RNA - parathyroid gland [nTPM]":"67.9","Tissue RNA - pituitary gland [nTPM]":"40.4","Tissue RNA - placenta [nTPM]":"72.5","Tissue RNA - pons [nTPM]":"77.5","Tissue RNA - prostate [nTPM]":"56.1","Tissue RNA - rectum [nTPM]":"102.9","Tissue RNA - retina [nTPM]":"45.9","Tissue RNA - salivary gland [nTPM]":"82.6","Tissue RNA - seminal vesicle [nTPM]":"42.7","Tissue RNA - skeletal muscle [nTPM]":"60.9","Tissue RNA - skin 1 [nTPM]":"107.1","Tissue RNA - small intestine [nTPM]":"81.1","Tissue RNA - smooth muscle [nTPM]":"66.0","Tissue RNA - spinal cord [nTPM]":"53.6","Tissue RNA - spleen [nTPM]":"59.3","Tissue RNA - stomach 1 [nTPM]":"81.5","Tissue RNA - testis [nTPM]":"42.0","Tissue RNA - thalamus [nTPM]":"55.0","Tissue RNA - thymus [nTPM]":"72.6","Tissue RNA - thyroid gland [nTPM]":"46.8","Tissue RNA - tongue [nTPM]":"66.7","Tissue RNA - tonsil [nTPM]":"102.3","Tissue RNA - urinary bladder [nTPM]":"47.0","Tissue RNA - vagina [nTPM]":"76.8","Tissue RNA - white matter [nTPM]":"55.0","Cell RNA - A-431 [nTPM]":"293.9","Cell RNA - A549 [nTPM]":"156.2","Cell RNA - AF22 [nTPM]":"561.5","Cell RNA - AN3-CA [nTPM]":"204.4","Cell RNA - ASC diff [nTPM]":"128.7","Cell RNA - ASC TERT1 [nTPM]":"467.7","Cell RNA - BEWO [nTPM]":"199.6","Cell RNA - BJ [nTPM]":"136.8","Cell RNA - BJ hTERT+ [nTPM]":"268.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"213.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"344.2","Cell RNA - CACO-2 [nTPM]":"255.4","Cell RNA - CAPAN-2 [nTPM]":"677.7","Cell RNA - Daudi [nTPM]":"222.3","Cell RNA - EFO-21 [nTPM]":"323.6","Cell RNA - fHDF\/TERT166 [nTPM]":"120.6","Cell RNA - GAMG [nTPM]":"506.9","Cell RNA - HaCaT [nTPM]":"319.1","Cell RNA - HAP1 [nTPM]":"338.9","Cell RNA - HBEC3-KT [nTPM]":"1187.5","Cell RNA - HBF TERT88 [nTPM]":"198.9","Cell RNA - HDLM-2 [nTPM]":"122.4","Cell RNA - HEK 293 [nTPM]":"242.5","Cell RNA - HEL [nTPM]":"129.4","Cell RNA - HeLa [nTPM]":"260.1","Cell RNA - Hep G2 [nTPM]":"311.5","Cell RNA - HHSteC [nTPM]":"210.8","Cell RNA - HL-60 [nTPM]":"212.1","Cell RNA - HMC-1 [nTPM]":"142.0","Cell RNA - HSkMC [nTPM]":"335.5","Cell RNA - hTCEpi [nTPM]":"184.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"339.6","Cell RNA - hTERT-HME1 [nTPM]":"168.8","Cell RNA - hTERT-RPE1 [nTPM]":"96.4","Cell RNA - HUVEC TERT2 [nTPM]":"377.6","Cell RNA - JURKAT [nTPM]":"322.3","Cell RNA - K-562 [nTPM]":"235.1","Cell RNA - Karpas-707 [nTPM]":"579.9","Cell RNA - LHCN-M2 [nTPM]":"225.3","Cell RNA - MCF7 [nTPM]":"315.1","Cell RNA - MOLT-4 [nTPM]":"273.6","Cell RNA - NB-4 [nTPM]":"205.0","Cell RNA - NTERA-2 [nTPM]":"338.9","Cell RNA - OE19 [nTPM]":"216.4","Cell RNA - PC-3 [nTPM]":"225.5","Cell RNA - REH [nTPM]":"231.6","Cell RNA - RH-30 [nTPM]":"243.2","Cell RNA - RPMI-8226 [nTPM]":"620.0","Cell RNA - RPTEC TERT1 [nTPM]":"567.7","Cell RNA - RT4 [nTPM]":"193.0","Cell RNA - SCLC-21H [nTPM]":"217.4","Cell RNA - SH-SY5Y [nTPM]":"185.6","Cell RNA - SiHa [nTPM]":"140.7","Cell RNA - SK-BR-3 [nTPM]":"253.0","Cell RNA - SK-MEL-30 [nTPM]":"243.0","Cell RNA - SuSa [nTPM]":"317.3","Cell RNA - T-47d [nTPM]":"182.6","Cell RNA - THP-1 [nTPM]":"567.6","Cell RNA - TIME [nTPM]":"277.1","Cell RNA - U-138 MG [nTPM]":"118.4","Cell RNA - U-2 OS [nTPM]":"144.3","Cell RNA - U-2197 [nTPM]":"74.3","Cell RNA - U-251 MG [nTPM]":"254.9","Cell RNA - U-266\/70 [nTPM]":"244.3","Cell RNA - U-266\/84 [nTPM]":"202.3","Cell RNA - U-698 [nTPM]":"401.1","Cell RNA - U-87 MG [nTPM]":"115.3","Cell RNA - U-937 [nTPM]":"221.7","Cell RNA - WM-115 [nTPM]":"191.1","Blood RNA - basophil [nTPM]":"90.6","Blood RNA - classical monocyte [nTPM]":"85.5","Blood RNA - eosinophil [nTPM]":"124.1","Blood RNA - gdT-cell [nTPM]":"89.2","Blood RNA - intermediate monocyte [nTPM]":"92.9","Blood RNA - MAIT T-cell [nTPM]":"79.7","Blood RNA - memory B-cell [nTPM]":"102.8","Blood RNA - memory CD4 T-cell [nTPM]":"77.8","Blood RNA - memory CD8 T-cell [nTPM]":"91.1","Blood RNA - myeloid DC [nTPM]":"95.6","Blood RNA - naive B-cell [nTPM]":"95.1","Blood RNA - naive CD4 T-cell [nTPM]":"69.9","Blood RNA - naive CD8 T-cell [nTPM]":"87.1","Blood RNA - neutrophil [nTPM]":"38.9","Blood RNA - NK-cell [nTPM]":"115.2","Blood RNA - non-classical monocyte [nTPM]":"70.0","Blood RNA - plasmacytoid DC [nTPM]":"76.2","Blood RNA - T-reg [nTPM]":"113.7","Blood RNA - total PBMC [nTPM]":"134.7","Brain RNA - amygdala [nTPM]":"48.2","Brain RNA - basal ganglia [nTPM]":"50.4","Brain RNA - cerebellum [nTPM]":"60.1","Brain RNA - cerebral cortex [nTPM]":"58.8","Brain RNA - hippocampal formation [nTPM]":"49.9","Brain RNA - hypothalamus [nTPM]":"64.6","Brain RNA - medulla oblongata [nTPM]":"71.1","Brain RNA - midbrain [nTPM]":"62.5","Brain RNA - pons [nTPM]":"77.5","Brain RNA - spinal cord [nTPM]":"53.6","Brain RNA - thalamus [nTPM]":"55.0","Brain RNA - white matter [nTPM]":"55.0","Single Cell Type RNA - Adipocytes [nTPM]":"154.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"181.6","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"68.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"83.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"927.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.1","Single Cell Type RNA - Bipolar cells [nTPM]":"69.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"84.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"56.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"97.2","Single Cell Type RNA - Club cells [nTPM]":"431.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"207.8","Single Cell Type RNA - dendritic cells [nTPM]":"74.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"343.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"180.9","Single Cell Type RNA - Early spermatids [nTPM]":"216.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"56.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"161.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.4","Single Cell Type RNA - Erythroid cells [nTPM]":"133.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"329.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"198.7","Single Cell Type RNA - Fibroblasts [nTPM]":"59.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"77.8","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"116.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"168.1","Single Cell Type RNA - Hepatocytes [nTPM]":"361.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"112.0","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"28.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"135.7","Single Cell Type RNA - Ionocytes [nTPM]":"299.1","Single Cell Type RNA - Kupffer cells [nTPM]":"54.8","Single Cell Type RNA - Langerhans cells [nTPM]":"44.4","Single Cell Type RNA - Late spermatids [nTPM]":"67.9","Single Cell Type RNA - Leydig cells [nTPM]":"60.9","Single Cell Type RNA - Macrophages [nTPM]":"52.8","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"144.7","Single Cell Type RNA - Muller glia cells [nTPM]":"81.1","Single Cell Type RNA - NK-cells [nTPM]":"87.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"256.7","Single Cell Type RNA - Paneth cells [nTPM]":"324.3","Single Cell Type RNA - Peritubular cells [nTPM]":"70.3","Single Cell Type RNA - Plasma cells [nTPM]":"91.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"206.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"194.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"145.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"129.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"90.8","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"177.5","Single Cell Type RNA - Spermatocytes [nTPM]":"42.0","Single Cell Type RNA - Spermatogonia [nTPM]":"14.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"49.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.5","Single Cell Type RNA - T-cells [nTPM]":"68.3","Single Cell Type RNA - Theca cells [nTPM]":"230.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"165.4","Single Cell Type RNA - Urothelial cells [nTPM]":"148.2"},{"Gene":"GGPS1","Gene synonym":["GGPPS1"],"Ensembl":"ENSG00000152904","Gene description":"Geranylgeranyl diphosphate synthase 1","Uniprot":["O95749"],"Chromosome":"1","Position":"235327350-235344532","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Isoprene biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"212.7","Late spermatids":"290.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029472","HPA050727"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA029472":"AB_10696206","HPA050727":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.69e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.0","Tissue RNA - adrenal gland [nTPM]":"23.5","Tissue RNA - amygdala [nTPM]":"20.4","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"21.4","Tissue RNA - bone marrow [nTPM]":"7.8","Tissue RNA - breast [nTPM]":"34.1","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"27.6","Tissue RNA - cervix [nTPM]":"24.5","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"24.8","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"23.3","Tissue RNA - epididymis [nTPM]":"30.4","Tissue RNA - esophagus [nTPM]":"22.4","Tissue RNA - fallopian tube [nTPM]":"21.2","Tissue RNA - gallbladder [nTPM]":"20.0","Tissue RNA - heart muscle [nTPM]":"23.5","Tissue RNA - hippocampal formation [nTPM]":"21.1","Tissue RNA - hypothalamus [nTPM]":"22.5","Tissue RNA - kidney [nTPM]":"27.8","Tissue RNA - liver [nTPM]":"21.7","Tissue RNA - lung [nTPM]":"20.1","Tissue RNA - lymph node [nTPM]":"21.3","Tissue RNA - medulla oblongata [nTPM]":"21.8","Tissue RNA - midbrain [nTPM]":"20.6","Tissue RNA - ovary [nTPM]":"23.3","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"21.1","Tissue RNA - pituitary gland [nTPM]":"17.6","Tissue RNA - placenta [nTPM]":"19.2","Tissue RNA - pons [nTPM]":"22.3","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"23.9","Tissue RNA - retina [nTPM]":"38.8","Tissue RNA - salivary gland [nTPM]":"31.2","Tissue RNA - seminal vesicle [nTPM]":"19.7","Tissue RNA - skeletal muscle [nTPM]":"29.8","Tissue RNA - skin 1 [nTPM]":"20.3","Tissue RNA - small intestine [nTPM]":"20.6","Tissue RNA - smooth muscle [nTPM]":"25.7","Tissue RNA - spinal cord [nTPM]":"22.3","Tissue RNA - spleen [nTPM]":"20.5","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"48.2","Tissue RNA - thalamus [nTPM]":"20.9","Tissue RNA - thymus [nTPM]":"27.6","Tissue RNA - thyroid gland [nTPM]":"27.4","Tissue RNA - tongue [nTPM]":"28.9","Tissue RNA - tonsil [nTPM]":"21.9","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"25.7","Cell RNA - A-431 [nTPM]":"41.3","Cell RNA - A549 [nTPM]":"22.3","Cell RNA - AF22 [nTPM]":"54.5","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"41.7","Cell RNA - ASC TERT1 [nTPM]":"59.9","Cell RNA - BEWO [nTPM]":"20.5","Cell RNA - BJ [nTPM]":"36.2","Cell RNA - BJ hTERT+ [nTPM]":"50.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.1","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"64.5","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"51.3","Cell RNA - fHDF\/TERT166 [nTPM]":"40.6","Cell RNA - GAMG [nTPM]":"38.1","Cell RNA - HaCaT [nTPM]":"33.5","Cell RNA - HAP1 [nTPM]":"29.4","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"31.2","Cell RNA - HDLM-2 [nTPM]":"28.8","Cell RNA - HEK 293 [nTPM]":"54.4","Cell RNA - HEL [nTPM]":"24.0","Cell RNA - HeLa [nTPM]":"19.7","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"46.9","Cell RNA - HL-60 [nTPM]":"30.0","Cell RNA - HMC-1 [nTPM]":"19.7","Cell RNA - HSkMC [nTPM]":"39.3","Cell RNA - hTCEpi [nTPM]":"66.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.2","Cell RNA - hTERT-HME1 [nTPM]":"43.0","Cell RNA - hTERT-RPE1 [nTPM]":"41.8","Cell RNA - HUVEC TERT2 [nTPM]":"42.5","Cell RNA - JURKAT [nTPM]":"46.2","Cell RNA - K-562 [nTPM]":"58.5","Cell RNA - Karpas-707 [nTPM]":"24.7","Cell RNA - LHCN-M2 [nTPM]":"31.5","Cell RNA - MCF7 [nTPM]":"24.6","Cell RNA - MOLT-4 [nTPM]":"37.0","Cell RNA - NB-4 [nTPM]":"35.7","Cell RNA - NTERA-2 [nTPM]":"46.4","Cell RNA - OE19 [nTPM]":"109.9","Cell RNA - PC-3 [nTPM]":"11.5","Cell RNA - REH [nTPM]":"22.6","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"32.6","Cell RNA - RPTEC TERT1 [nTPM]":"66.2","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"43.3","Cell RNA - SH-SY5Y [nTPM]":"59.8","Cell RNA - SiHa [nTPM]":"27.3","Cell RNA - SK-BR-3 [nTPM]":"61.5","Cell RNA - SK-MEL-30 [nTPM]":"54.7","Cell RNA - SuSa [nTPM]":"20.1","Cell RNA - T-47d [nTPM]":"76.7","Cell RNA - THP-1 [nTPM]":"46.5","Cell RNA - TIME [nTPM]":"35.9","Cell RNA - U-138 MG [nTPM]":"27.9","Cell RNA - U-2 OS [nTPM]":"20.8","Cell RNA - U-2197 [nTPM]":"47.6","Cell RNA - U-251 MG [nTPM]":"34.7","Cell RNA - U-266\/70 [nTPM]":"42.0","Cell RNA - U-266\/84 [nTPM]":"55.8","Cell RNA - U-698 [nTPM]":"34.3","Cell RNA - U-87 MG [nTPM]":"35.4","Cell RNA - U-937 [nTPM]":"33.3","Cell RNA - WM-115 [nTPM]":"51.4","Blood RNA - basophil [nTPM]":"43.7","Blood RNA - classical monocyte [nTPM]":"31.0","Blood RNA - eosinophil [nTPM]":"48.5","Blood RNA - gdT-cell [nTPM]":"31.5","Blood RNA - intermediate monocyte [nTPM]":"37.3","Blood RNA - MAIT T-cell [nTPM]":"32.1","Blood RNA - memory B-cell [nTPM]":"38.6","Blood RNA - memory CD4 T-cell [nTPM]":"39.5","Blood RNA - memory CD8 T-cell [nTPM]":"33.8","Blood RNA - myeloid DC [nTPM]":"30.4","Blood RNA - naive B-cell [nTPM]":"32.8","Blood RNA - naive CD4 T-cell [nTPM]":"36.2","Blood RNA - naive CD8 T-cell [nTPM]":"33.4","Blood RNA - neutrophil [nTPM]":"27.8","Blood RNA - NK-cell [nTPM]":"31.9","Blood RNA - non-classical monocyte [nTPM]":"54.2","Blood RNA - plasmacytoid DC [nTPM]":"25.2","Blood RNA - T-reg [nTPM]":"42.5","Blood RNA - total PBMC [nTPM]":"36.8","Brain RNA - amygdala [nTPM]":"20.4","Brain RNA - basal ganglia [nTPM]":"21.4","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"27.6","Brain RNA - hippocampal formation [nTPM]":"21.1","Brain RNA - hypothalamus [nTPM]":"22.5","Brain RNA - medulla oblongata [nTPM]":"21.8","Brain RNA - midbrain [nTPM]":"20.6","Brain RNA - pons [nTPM]":"22.3","Brain RNA - spinal cord [nTPM]":"22.3","Brain RNA - thalamus [nTPM]":"20.9","Brain RNA - white matter [nTPM]":"25.7","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"27.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"32.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"39.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"212.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.4","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.7","Single Cell Type RNA - Fibroblasts [nTPM]":"31.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"16.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.1","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.0","Single Cell Type RNA - Late spermatids [nTPM]":"290.7","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"24.3","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"36.7","Single Cell Type RNA - Muller glia cells [nTPM]":"55.4","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.8","Single Cell Type RNA - Paneth cells [nTPM]":"23.3","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"8.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.5","Single Cell Type RNA - Spermatocytes [nTPM]":"111.6","Single Cell Type RNA - Spermatogonia [nTPM]":"50.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.1","Single Cell Type RNA - T-cells [nTPM]":"33.0","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.7","Single Cell Type RNA - Urothelial cells [nTPM]":"55.9"},{"Gene":"HMGCL","Gene synonym":["HL"],"Ensembl":"ENSG00000117305","Gene description":"3-hydroxy-3-methylglutaryl-CoA lyase","Uniprot":["P35914"],"Chromosome":"1","Position":"23801885-23838620","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"322.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"172.4","Proximal tubular cells":"216.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004727"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004727":"AB_1079074"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.67e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"63.0","Tissue RNA - amygdala [nTPM]":"26.3","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"7.5","Tissue RNA - breast [nTPM]":"25.8","Tissue RNA - cerebellum [nTPM]":"27.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"33.0","Tissue RNA - colon [nTPM]":"53.3","Tissue RNA - duodenum [nTPM]":"45.7","Tissue RNA - endometrium 1 [nTPM]":"20.2","Tissue RNA - epididymis [nTPM]":"47.2","Tissue RNA - esophagus [nTPM]":"32.8","Tissue RNA - fallopian tube [nTPM]":"35.6","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"42.5","Tissue RNA - hippocampal formation [nTPM]":"24.6","Tissue RNA - hypothalamus [nTPM]":"26.9","Tissue RNA - kidney [nTPM]":"115.5","Tissue RNA - liver [nTPM]":"322.5","Tissue RNA - lung [nTPM]":"23.6","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"28.0","Tissue RNA - midbrain [nTPM]":"26.2","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"33.4","Tissue RNA - parathyroid gland [nTPM]":"60.2","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"19.9","Tissue RNA - pons [nTPM]":"27.7","Tissue RNA - prostate [nTPM]":"31.7","Tissue RNA - rectum [nTPM]":"52.9","Tissue RNA - retina [nTPM]":"16.1","Tissue RNA - salivary gland [nTPM]":"30.3","Tissue RNA - seminal vesicle [nTPM]":"27.9","Tissue RNA - skeletal muscle [nTPM]":"63.7","Tissue RNA - skin 1 [nTPM]":"25.5","Tissue RNA - small intestine [nTPM]":"40.0","Tissue RNA - smooth muscle [nTPM]":"23.3","Tissue RNA - spinal cord [nTPM]":"27.4","Tissue RNA - spleen [nTPM]":"26.8","Tissue RNA - stomach 1 [nTPM]":"40.9","Tissue RNA - testis [nTPM]":"17.9","Tissue RNA - thalamus [nTPM]":"30.1","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"70.2","Tissue RNA - tonsil [nTPM]":"25.1","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"24.2","Tissue RNA - white matter [nTPM]":"29.6","Cell RNA - A-431 [nTPM]":"28.5","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"17.7","Cell RNA - AN3-CA [nTPM]":"13.4","Cell RNA - ASC diff [nTPM]":"70.6","Cell RNA - ASC TERT1 [nTPM]":"53.5","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"22.0","Cell RNA - BJ hTERT+ [nTPM]":"38.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"53.7","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"44.3","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"22.4","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"35.7","Cell RNA - HBF TERT88 [nTPM]":"25.2","Cell RNA - HDLM-2 [nTPM]":"30.4","Cell RNA - HEK 293 [nTPM]":"16.1","Cell RNA - HEL [nTPM]":"19.8","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"90.9","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"62.4","Cell RNA - hTCEpi [nTPM]":"52.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.8","Cell RNA - hTERT-HME1 [nTPM]":"58.5","Cell RNA - hTERT-RPE1 [nTPM]":"62.5","Cell RNA - HUVEC TERT2 [nTPM]":"32.2","Cell RNA - JURKAT [nTPM]":"27.4","Cell RNA - K-562 [nTPM]":"20.6","Cell RNA - Karpas-707 [nTPM]":"20.3","Cell RNA - LHCN-M2 [nTPM]":"43.3","Cell RNA - MCF7 [nTPM]":"29.3","Cell RNA - MOLT-4 [nTPM]":"12.2","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"77.4","Cell RNA - PC-3 [nTPM]":"22.1","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"14.5","Cell RNA - RPMI-8226 [nTPM]":"27.9","Cell RNA - RPTEC TERT1 [nTPM]":"55.4","Cell RNA - RT4 [nTPM]":"14.5","Cell RNA - SCLC-21H [nTPM]":"14.8","Cell RNA - SH-SY5Y [nTPM]":"13.2","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"10.8","Cell RNA - SK-MEL-30 [nTPM]":"49.3","Cell RNA - SuSa [nTPM]":"23.3","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"35.5","Cell RNA - U-251 MG [nTPM]":"9.7","Cell RNA - U-266\/70 [nTPM]":"28.7","Cell RNA - U-266\/84 [nTPM]":"15.2","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"47.7","Cell RNA - U-937 [nTPM]":"28.7","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"103.5","Blood RNA - classical monocyte [nTPM]":"67.0","Blood RNA - eosinophil [nTPM]":"66.0","Blood RNA - gdT-cell [nTPM]":"36.3","Blood RNA - intermediate monocyte [nTPM]":"66.0","Blood RNA - MAIT T-cell [nTPM]":"39.8","Blood RNA - memory B-cell [nTPM]":"45.9","Blood RNA - memory CD4 T-cell [nTPM]":"39.1","Blood RNA - memory CD8 T-cell [nTPM]":"42.1","Blood RNA - myeloid DC [nTPM]":"58.0","Blood RNA - naive B-cell [nTPM]":"51.2","Blood RNA - naive CD4 T-cell [nTPM]":"39.6","Blood RNA - naive CD8 T-cell [nTPM]":"37.7","Blood RNA - neutrophil [nTPM]":"25.5","Blood RNA - NK-cell [nTPM]":"54.4","Blood RNA - non-classical monocyte [nTPM]":"77.5","Blood RNA - plasmacytoid DC [nTPM]":"43.9","Blood RNA - T-reg [nTPM]":"45.5","Blood RNA - total PBMC [nTPM]":"61.7","Brain RNA - amygdala [nTPM]":"26.3","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"27.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"24.6","Brain RNA - hypothalamus [nTPM]":"26.9","Brain RNA - medulla oblongata [nTPM]":"28.0","Brain RNA - midbrain [nTPM]":"26.2","Brain RNA - pons [nTPM]":"27.7","Brain RNA - spinal cord [nTPM]":"27.4","Brain RNA - thalamus [nTPM]":"30.1","Brain RNA - white matter [nTPM]":"29.6","Single Cell Type RNA - Adipocytes [nTPM]":"19.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"16.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"24.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"30.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.0","Single Cell Type RNA - dendritic cells [nTPM]":"10.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"119.3","Single Cell Type RNA - Ductal cells [nTPM]":"57.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.3","Single Cell Type RNA - Fibroblasts [nTPM]":"20.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"172.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"61.6","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"23.5","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"41.4","Single Cell Type RNA - Muller glia cells [nTPM]":"37.1","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.2","Single Cell Type RNA - Paneth cells [nTPM]":"53.8","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"70.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"216.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.3","Single Cell Type RNA - T-cells [nTPM]":"15.2","Single Cell Type RNA - Theca cells [nTPM]":"65.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.9","Single Cell Type RNA - Urothelial cells [nTPM]":"24.3"},{"Gene":"HMGCLL1","Gene synonym":["bA418P12.1","DKFZP434G1411"],"Ensembl":"ENSG00000146151","Gene description":"3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1","Uniprot":["Q8TB92"],"Chromosome":"6","Position":"55434373-55579197","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"49.9","Excitatory neurons":"80.7","Inhibitory neurons":"76.2","Oligodendrocytes":"23.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SCLC-21H":"5.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"8.3","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"8.3","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"49.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"80.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HMGCR","Gene synonym":[],"Ensembl":"ENSG00000113161","Gene description":"3-hydroxy-3-methylglutaryl-CoA reductase","Uniprot":["P04035"],"Chromosome":"5","Position":"75336329-75364001","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"105.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"239.5","Theca cells":"148.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008338","CAB016797","CAB078688"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016797":null,"CAB078688":"AB_2665607","HPA008338":"AB_10960401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"39.5","Tissue RNA - amygdala [nTPM]":"19.8","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"20.7","Tissue RNA - bone marrow [nTPM]":"24.6","Tissue RNA - breast [nTPM]":"30.8","Tissue RNA - cerebellum [nTPM]":"15.7","Tissue RNA - cerebral cortex [nTPM]":"23.0","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"45.2","Tissue RNA - duodenum [nTPM]":"38.1","Tissue RNA - endometrium 1 [nTPM]":"16.8","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"49.1","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"15.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"25.0","Tissue RNA - kidney [nTPM]":"21.1","Tissue RNA - liver [nTPM]":"105.7","Tissue RNA - lung [nTPM]":"24.2","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"26.6","Tissue RNA - midbrain [nTPM]":"21.3","Tissue RNA - ovary [nTPM]":"9.7","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"24.8","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"25.2","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"37.3","Tissue RNA - retina [nTPM]":"18.7","Tissue RNA - salivary gland [nTPM]":"15.5","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"55.2","Tissue RNA - small intestine [nTPM]":"26.5","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"23.3","Tissue RNA - thalamus [nTPM]":"20.5","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"23.4","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"26.7","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"68.5","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"260.7","Cell RNA - AN3-CA [nTPM]":"89.2","Cell RNA - ASC diff [nTPM]":"54.9","Cell RNA - ASC TERT1 [nTPM]":"103.4","Cell RNA - BEWO [nTPM]":"65.5","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"53.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"85.0","Cell RNA - CACO-2 [nTPM]":"95.8","Cell RNA - CAPAN-2 [nTPM]":"163.7","Cell RNA - Daudi [nTPM]":"60.3","Cell RNA - EFO-21 [nTPM]":"68.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.7","Cell RNA - GAMG [nTPM]":"245.2","Cell RNA - HaCaT [nTPM]":"84.5","Cell RNA - HAP1 [nTPM]":"136.4","Cell RNA - HBEC3-KT [nTPM]":"225.9","Cell RNA - HBF TERT88 [nTPM]":"39.4","Cell RNA - HDLM-2 [nTPM]":"20.8","Cell RNA - HEK 293 [nTPM]":"50.8","Cell RNA - HEL [nTPM]":"47.0","Cell RNA - HeLa [nTPM]":"36.7","Cell RNA - Hep G2 [nTPM]":"78.6","Cell RNA - HHSteC [nTPM]":"80.8","Cell RNA - HL-60 [nTPM]":"39.8","Cell RNA - HMC-1 [nTPM]":"32.9","Cell RNA - HSkMC [nTPM]":"66.8","Cell RNA - hTCEpi [nTPM]":"130.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.6","Cell RNA - hTERT-HME1 [nTPM]":"65.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"84.8","Cell RNA - K-562 [nTPM]":"50.4","Cell RNA - Karpas-707 [nTPM]":"86.4","Cell RNA - LHCN-M2 [nTPM]":"61.0","Cell RNA - MCF7 [nTPM]":"45.2","Cell RNA - MOLT-4 [nTPM]":"72.7","Cell RNA - NB-4 [nTPM]":"39.9","Cell RNA - NTERA-2 [nTPM]":"112.5","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"19.7","Cell RNA - REH [nTPM]":"50.7","Cell RNA - RH-30 [nTPM]":"78.7","Cell RNA - RPMI-8226 [nTPM]":"86.5","Cell RNA - RPTEC TERT1 [nTPM]":"155.2","Cell RNA - RT4 [nTPM]":"154.5","Cell RNA - SCLC-21H [nTPM]":"91.0","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"43.7","Cell RNA - SK-MEL-30 [nTPM]":"38.3","Cell RNA - SuSa [nTPM]":"89.6","Cell RNA - T-47d [nTPM]":"43.1","Cell RNA - THP-1 [nTPM]":"102.4","Cell RNA - TIME [nTPM]":"37.2","Cell RNA - U-138 MG [nTPM]":"20.5","Cell RNA - U-2 OS [nTPM]":"30.0","Cell RNA - U-2197 [nTPM]":"22.4","Cell RNA - U-251 MG [nTPM]":"32.8","Cell RNA - U-266\/70 [nTPM]":"28.1","Cell RNA - U-266\/84 [nTPM]":"38.1","Cell RNA - U-698 [nTPM]":"83.2","Cell RNA - U-87 MG [nTPM]":"29.7","Cell RNA - U-937 [nTPM]":"75.2","Cell RNA - WM-115 [nTPM]":"43.7","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"14.8","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"8.9","Blood RNA - MAIT T-cell [nTPM]":"6.2","Blood RNA - memory B-cell [nTPM]":"5.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"16.9","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.3","Blood RNA - naive CD8 T-cell [nTPM]":"7.2","Blood RNA - neutrophil [nTPM]":"28.8","Blood RNA - NK-cell [nTPM]":"12.5","Blood RNA - non-classical monocyte [nTPM]":"10.5","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"9.0","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"19.8","Brain RNA - basal ganglia [nTPM]":"20.7","Brain RNA - cerebellum [nTPM]":"15.7","Brain RNA - cerebral cortex [nTPM]":"23.0","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"25.0","Brain RNA - medulla oblongata [nTPM]":"26.6","Brain RNA - midbrain [nTPM]":"21.3","Brain RNA - pons [nTPM]":"25.2","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"20.5","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.3","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"14.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"23.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"33.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.7","Single Cell Type RNA - dendritic cells [nTPM]":"25.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"80.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"46.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"124.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"239.5","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"71.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"97.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.1","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"11.8","Single Cell Type RNA - Late spermatids [nTPM]":"22.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"19.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"12.1","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"40.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"23.4","Single Cell Type RNA - Spermatogonia [nTPM]":"12.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"69.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"91.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.7","Single Cell Type RNA - T-cells [nTPM]":"19.2","Single Cell Type RNA - Theca cells [nTPM]":"148.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.4","Single Cell Type RNA - Urothelial cells [nTPM]":"18.8"},{"Gene":"HMGCS1","Gene synonym":["HMGCS"],"Ensembl":"ENSG00000112972","Gene description":"3-hydroxy-3-methylglutaryl-CoA synthase 1","Uniprot":["Q01581"],"Chromosome":"5","Position":"43287470-43313512","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"390.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"511.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"797.7","GAMG":"523.5","HBEC3-KT":"467.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032907","HPA036913","HPA036914"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB032907":"AB_2118319","HPA036913":"AB_2675380","HPA036914":"AB_10671751"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.2","Tissue RNA - adrenal gland [nTPM]":"55.2","Tissue RNA - amygdala [nTPM]":"25.2","Tissue RNA - appendix [nTPM]":"27.2","Tissue RNA - basal ganglia [nTPM]":"32.9","Tissue RNA - bone marrow [nTPM]":"15.8","Tissue RNA - breast [nTPM]":"40.1","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"38.6","Tissue RNA - cervix [nTPM]":"56.4","Tissue RNA - choroid plexus [nTPM]":"16.8","Tissue RNA - colon [nTPM]":"50.2","Tissue RNA - duodenum [nTPM]":"93.6","Tissue RNA - endometrium 1 [nTPM]":"19.8","Tissue RNA - epididymis [nTPM]":"36.1","Tissue RNA - esophagus [nTPM]":"137.5","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"23.3","Tissue RNA - heart muscle [nTPM]":"16.1","Tissue RNA - hippocampal formation [nTPM]":"36.1","Tissue RNA - hypothalamus [nTPM]":"44.6","Tissue RNA - kidney [nTPM]":"32.8","Tissue RNA - liver [nTPM]":"390.2","Tissue RNA - lung [nTPM]":"51.4","Tissue RNA - lymph node [nTPM]":"21.5","Tissue RNA - medulla oblongata [nTPM]":"46.5","Tissue RNA - midbrain [nTPM]":"34.7","Tissue RNA - ovary [nTPM]":"21.6","Tissue RNA - pancreas [nTPM]":"26.6","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"22.5","Tissue RNA - pons [nTPM]":"47.2","Tissue RNA - prostate [nTPM]":"40.5","Tissue RNA - rectum [nTPM]":"45.4","Tissue RNA - retina [nTPM]":"34.2","Tissue RNA - salivary gland [nTPM]":"53.2","Tissue RNA - seminal vesicle [nTPM]":"15.7","Tissue RNA - skeletal muscle [nTPM]":"17.8","Tissue RNA - skin 1 [nTPM]":"85.9","Tissue RNA - small intestine [nTPM]":"47.2","Tissue RNA - smooth muscle [nTPM]":"19.9","Tissue RNA - spinal cord [nTPM]":"24.7","Tissue RNA - spleen [nTPM]":"14.8","Tissue RNA - stomach 1 [nTPM]":"43.4","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"35.3","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"23.6","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"31.5","Tissue RNA - urinary bladder [nTPM]":"18.3","Tissue RNA - vagina [nTPM]":"69.5","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"103.4","Cell RNA - A549 [nTPM]":"48.8","Cell RNA - AF22 [nTPM]":"797.7","Cell RNA - AN3-CA [nTPM]":"93.0","Cell RNA - ASC diff [nTPM]":"45.8","Cell RNA - ASC TERT1 [nTPM]":"178.4","Cell RNA - BEWO [nTPM]":"54.1","Cell RNA - BJ [nTPM]":"16.2","Cell RNA - BJ hTERT+ [nTPM]":"63.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.2","Cell RNA - CACO-2 [nTPM]":"86.6","Cell RNA - CAPAN-2 [nTPM]":"146.6","Cell RNA - Daudi [nTPM]":"108.4","Cell RNA - EFO-21 [nTPM]":"35.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.3","Cell RNA - GAMG [nTPM]":"523.5","Cell RNA - HaCaT [nTPM]":"80.2","Cell RNA - HAP1 [nTPM]":"199.7","Cell RNA - HBEC3-KT [nTPM]":"467.2","Cell RNA - HBF TERT88 [nTPM]":"24.1","Cell RNA - HDLM-2 [nTPM]":"23.5","Cell RNA - HEK 293 [nTPM]":"240.7","Cell RNA - HEL [nTPM]":"40.1","Cell RNA - HeLa [nTPM]":"45.3","Cell RNA - Hep G2 [nTPM]":"119.3","Cell RNA - HHSteC [nTPM]":"71.3","Cell RNA - HL-60 [nTPM]":"88.0","Cell RNA - HMC-1 [nTPM]":"28.0","Cell RNA - HSkMC [nTPM]":"98.5","Cell RNA - hTCEpi [nTPM]":"56.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"119.5","Cell RNA - hTERT-HME1 [nTPM]":"47.9","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"23.7","Cell RNA - JURKAT [nTPM]":"98.4","Cell RNA - K-562 [nTPM]":"73.1","Cell RNA - Karpas-707 [nTPM]":"291.7","Cell RNA - LHCN-M2 [nTPM]":"19.4","Cell RNA - MCF7 [nTPM]":"48.9","Cell RNA - MOLT-4 [nTPM]":"81.3","Cell RNA - NB-4 [nTPM]":"111.9","Cell RNA - NTERA-2 [nTPM]":"143.1","Cell RNA - OE19 [nTPM]":"41.7","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"57.5","Cell RNA - RH-30 [nTPM]":"111.9","Cell RNA - RPMI-8226 [nTPM]":"121.8","Cell RNA - RPTEC TERT1 [nTPM]":"357.7","Cell RNA - RT4 [nTPM]":"158.2","Cell RNA - SCLC-21H [nTPM]":"68.2","Cell RNA - SH-SY5Y [nTPM]":"33.0","Cell RNA - SiHa [nTPM]":"83.6","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"25.9","Cell RNA - SuSa [nTPM]":"114.5","Cell RNA - T-47d [nTPM]":"63.6","Cell RNA - THP-1 [nTPM]":"116.7","Cell RNA - TIME [nTPM]":"28.3","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"85.7","Cell RNA - U-2197 [nTPM]":"18.0","Cell RNA - U-251 MG [nTPM]":"15.5","Cell RNA - U-266\/70 [nTPM]":"38.8","Cell RNA - U-266\/84 [nTPM]":"64.0","Cell RNA - U-698 [nTPM]":"148.3","Cell RNA - U-87 MG [nTPM]":"15.0","Cell RNA - U-937 [nTPM]":"106.2","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"25.2","Brain RNA - basal ganglia [nTPM]":"32.9","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"38.6","Brain RNA - hippocampal formation [nTPM]":"36.1","Brain RNA - hypothalamus [nTPM]":"44.6","Brain RNA - medulla oblongata [nTPM]":"46.5","Brain RNA - midbrain [nTPM]":"34.7","Brain RNA - pons [nTPM]":"47.2","Brain RNA - spinal cord [nTPM]":"24.7","Brain RNA - thalamus [nTPM]":"35.3","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"27.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"172.6","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"44.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"108.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"93.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"68.3","Single Cell Type RNA - Bipolar cells [nTPM]":"43.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"46.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"79.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.3","Single Cell Type RNA - dendritic cells [nTPM]":"43.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"211.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"43.0","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"31.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"92.1","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.1","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"100.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"98.6","Single Cell Type RNA - granulocytes [nTPM]":"58.5","Single Cell Type RNA - Granulosa cells [nTPM]":"56.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"511.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"101.9","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"21.9","Single Cell Type RNA - Langerhans cells [nTPM]":"38.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"27.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"49.1","Single Cell Type RNA - Muller glia cells [nTPM]":"26.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"53.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.4","Single Cell Type RNA - Paneth cells [nTPM]":"132.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"38.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"149.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.8","Single Cell Type RNA - Spermatocytes [nTPM]":"20.0","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"197.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"236.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.5","Single Cell Type RNA - T-cells [nTPM]":"36.4","Single Cell Type RNA - Theca cells [nTPM]":"129.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"62.9","Single Cell Type RNA - Urothelial cells [nTPM]":"74.5"},{"Gene":"HSD17B4","Gene synonym":["DBP","MFE-2","SDR8C1"],"Ensembl":"ENSG00000133835","Gene description":"Hydroxysteroid 17-beta dehydrogenase 4","Uniprot":["P51659"],"Chromosome":"5","Position":"119452473-119637199","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Isomerase","Lyase","Oxidoreductase"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"320.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"225.1","Oligodendrocytes":"221.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"75.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021302","HPA021311","HPA021479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA021302":"AB_1844350","HPA021311":"AB_1844351","HPA021479":"AB_1844352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-3"},"Tissue RNA - adipose tissue [nTPM]":"74.4","Tissue RNA - adrenal gland [nTPM]":"85.0","Tissue RNA - amygdala [nTPM]":"37.2","Tissue RNA - appendix [nTPM]":"41.9","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"44.4","Tissue RNA - cerebellum [nTPM]":"51.1","Tissue RNA - cerebral cortex [nTPM]":"50.0","Tissue RNA - cervix [nTPM]":"68.8","Tissue RNA - choroid plexus [nTPM]":"47.2","Tissue RNA - colon [nTPM]":"64.5","Tissue RNA - duodenum [nTPM]":"79.3","Tissue RNA - endometrium 1 [nTPM]":"34.1","Tissue RNA - epididymis [nTPM]":"53.0","Tissue RNA - esophagus [nTPM]":"50.9","Tissue RNA - fallopian tube [nTPM]":"39.1","Tissue RNA - gallbladder [nTPM]":"52.5","Tissue RNA - heart muscle [nTPM]":"68.6","Tissue RNA - hippocampal formation [nTPM]":"34.9","Tissue RNA - hypothalamus [nTPM]":"50.7","Tissue RNA - kidney [nTPM]":"84.4","Tissue RNA - liver [nTPM]":"320.0","Tissue RNA - lung [nTPM]":"75.6","Tissue RNA - lymph node [nTPM]":"33.2","Tissue RNA - medulla oblongata [nTPM]":"50.6","Tissue RNA - midbrain [nTPM]":"49.5","Tissue RNA - ovary [nTPM]":"34.8","Tissue RNA - pancreas [nTPM]":"55.2","Tissue RNA - parathyroid gland [nTPM]":"75.5","Tissue RNA - pituitary gland [nTPM]":"26.5","Tissue RNA - placenta [nTPM]":"53.4","Tissue RNA - pons [nTPM]":"49.2","Tissue RNA - prostate [nTPM]":"56.8","Tissue RNA - rectum [nTPM]":"65.9","Tissue RNA - retina [nTPM]":"27.2","Tissue RNA - salivary gland [nTPM]":"44.9","Tissue RNA - seminal vesicle [nTPM]":"79.0","Tissue RNA - skeletal muscle [nTPM]":"59.8","Tissue RNA - skin 1 [nTPM]":"51.8","Tissue RNA - small intestine [nTPM]":"87.6","Tissue RNA - smooth muscle [nTPM]":"39.5","Tissue RNA - spinal cord [nTPM]":"44.7","Tissue RNA - spleen [nTPM]":"36.6","Tissue RNA - stomach 1 [nTPM]":"53.8","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"49.9","Tissue RNA - thymus [nTPM]":"31.9","Tissue RNA - thyroid gland [nTPM]":"133.9","Tissue RNA - tongue [nTPM]":"52.8","Tissue RNA - tonsil [nTPM]":"39.7","Tissue RNA - urinary bladder [nTPM]":"57.7","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"56.3","Cell RNA - A-431 [nTPM]":"68.8","Cell RNA - A549 [nTPM]":"59.8","Cell RNA - AF22 [nTPM]":"104.1","Cell RNA - AN3-CA [nTPM]":"143.7","Cell RNA - ASC diff [nTPM]":"261.8","Cell RNA - ASC TERT1 [nTPM]":"120.3","Cell RNA - BEWO [nTPM]":"57.9","Cell RNA - BJ [nTPM]":"63.4","Cell RNA - BJ hTERT+ [nTPM]":"80.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"103.0","Cell RNA - CACO-2 [nTPM]":"49.4","Cell RNA - CAPAN-2 [nTPM]":"112.8","Cell RNA - Daudi [nTPM]":"84.4","Cell RNA - EFO-21 [nTPM]":"128.0","Cell RNA - fHDF\/TERT166 [nTPM]":"70.6","Cell RNA - GAMG [nTPM]":"81.0","Cell RNA - HaCaT [nTPM]":"68.7","Cell RNA - HAP1 [nTPM]":"77.0","Cell RNA - HBEC3-KT [nTPM]":"144.4","Cell RNA - HBF TERT88 [nTPM]":"84.3","Cell RNA - HDLM-2 [nTPM]":"94.6","Cell RNA - HEK 293 [nTPM]":"79.8","Cell RNA - HEL [nTPM]":"118.1","Cell RNA - HeLa [nTPM]":"62.0","Cell RNA - Hep G2 [nTPM]":"96.9","Cell RNA - HHSteC [nTPM]":"65.8","Cell RNA - HL-60 [nTPM]":"38.0","Cell RNA - HMC-1 [nTPM]":"169.9","Cell RNA - HSkMC [nTPM]":"110.0","Cell RNA - hTCEpi [nTPM]":"56.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.9","Cell RNA - hTERT-HME1 [nTPM]":"54.7","Cell RNA - hTERT-RPE1 [nTPM]":"69.3","Cell RNA - HUVEC TERT2 [nTPM]":"103.9","Cell RNA - JURKAT [nTPM]":"59.4","Cell RNA - K-562 [nTPM]":"41.0","Cell RNA - Karpas-707 [nTPM]":"48.9","Cell RNA - LHCN-M2 [nTPM]":"64.2","Cell RNA - MCF7 [nTPM]":"64.0","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"82.1","Cell RNA - OE19 [nTPM]":"161.1","Cell RNA - PC-3 [nTPM]":"43.1","Cell RNA - REH [nTPM]":"68.7","Cell RNA - RH-30 [nTPM]":"103.0","Cell RNA - RPMI-8226 [nTPM]":"104.8","Cell RNA - RPTEC TERT1 [nTPM]":"92.2","Cell RNA - RT4 [nTPM]":"192.7","Cell RNA - SCLC-21H [nTPM]":"81.1","Cell RNA - SH-SY5Y [nTPM]":"70.6","Cell RNA - SiHa [nTPM]":"149.0","Cell RNA - SK-BR-3 [nTPM]":"23.4","Cell RNA - SK-MEL-30 [nTPM]":"78.7","Cell RNA - SuSa [nTPM]":"93.3","Cell RNA - T-47d [nTPM]":"88.7","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"67.6","Cell RNA - U-138 MG [nTPM]":"52.7","Cell RNA - U-2 OS [nTPM]":"38.1","Cell RNA - U-2197 [nTPM]":"66.5","Cell RNA - U-251 MG [nTPM]":"53.1","Cell RNA - U-266\/70 [nTPM]":"26.3","Cell RNA - U-266\/84 [nTPM]":"55.3","Cell RNA - U-698 [nTPM]":"32.6","Cell RNA - U-87 MG [nTPM]":"63.7","Cell RNA - U-937 [nTPM]":"104.4","Cell RNA - WM-115 [nTPM]":"56.7","Blood RNA - basophil [nTPM]":"75.5","Blood RNA - classical monocyte [nTPM]":"27.3","Blood RNA - eosinophil [nTPM]":"49.9","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"15.5","Blood RNA - MAIT T-cell [nTPM]":"7.3","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"21.3","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.2","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"17.1","Blood RNA - plasmacytoid DC [nTPM]":"13.8","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"37.2","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"51.1","Brain RNA - cerebral cortex [nTPM]":"50.0","Brain RNA - hippocampal formation [nTPM]":"34.9","Brain RNA - hypothalamus [nTPM]":"50.7","Brain RNA - medulla oblongata [nTPM]":"50.6","Brain RNA - midbrain [nTPM]":"49.5","Brain RNA - pons [nTPM]":"49.2","Brain RNA - spinal cord [nTPM]":"44.7","Brain RNA - thalamus [nTPM]":"49.9","Brain RNA - white matter [nTPM]":"56.3","Single Cell Type RNA - Adipocytes [nTPM]":"38.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"125.2","Single Cell Type RNA - Astrocytes [nTPM]":"47.3","Single Cell Type RNA - B-cells [nTPM]":"28.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"19.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"76.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"52.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"19.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"39.9","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"48.9","Single Cell Type RNA - Endothelial cells [nTPM]":"32.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.8","Single Cell Type RNA - granulocytes [nTPM]":"68.4","Single Cell Type RNA - Granulosa cells [nTPM]":"25.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"225.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"102.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.8","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"51.8","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.4","Single Cell Type RNA - Leydig cells [nTPM]":"34.5","Single Cell Type RNA - Macrophages [nTPM]":"46.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"85.7","Single Cell Type RNA - Muller glia cells [nTPM]":"47.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"221.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.6","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"85.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"65.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.2","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"65.0","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"57.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.3","Single Cell Type RNA - Urothelial cells [nTPM]":"39.7"},{"Gene":"HSD17B7","Gene synonym":["PRAP","SDR37C1"],"Ensembl":"ENSG00000132196","Gene description":"Hydroxysteroid 17-beta dehydrogenase 7","Uniprot":["P56937"],"Chromosome":"1","Position":"162790702-162812817","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"30.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047496":"AB_2680068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"16.1","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"6.0","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"30.2","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"8.3","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"5.9","Tissue RNA - rectum [nTPM]":"8.0","Tissue RNA - retina [nTPM]":"4.0","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"6.1","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"32.4","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"18.4","Cell RNA - ASC TERT1 [nTPM]":"18.3","Cell RNA - BEWO [nTPM]":"20.2","Cell RNA - BJ [nTPM]":"4.6","Cell RNA - BJ hTERT+ [nTPM]":"15.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.0","Cell RNA - CACO-2 [nTPM]":"17.0","Cell RNA - CAPAN-2 [nTPM]":"35.7","Cell RNA - Daudi [nTPM]":"29.6","Cell RNA - EFO-21 [nTPM]":"10.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"58.3","Cell RNA - HaCaT [nTPM]":"19.1","Cell RNA - HAP1 [nTPM]":"30.6","Cell RNA - HBEC3-KT [nTPM]":"43.4","Cell RNA - HBF TERT88 [nTPM]":"9.9","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"26.8","Cell RNA - HHSteC [nTPM]":"15.2","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"11.6","Cell RNA - hTCEpi [nTPM]":"23.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.8","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"7.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.7","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"8.9","Cell RNA - MOLT-4 [nTPM]":"17.7","Cell RNA - NB-4 [nTPM]":"13.7","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"24.4","Cell RNA - PC-3 [nTPM]":"15.3","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"19.3","Cell RNA - RPMI-8226 [nTPM]":"18.5","Cell RNA - RPTEC TERT1 [nTPM]":"33.3","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"27.6","Cell RNA - SH-SY5Y [nTPM]":"14.6","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"7.9","Cell RNA - SuSa [nTPM]":"27.5","Cell RNA - T-47d [nTPM]":"12.3","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"4.4","Cell RNA - U-2 OS [nTPM]":"10.2","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"10.0","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"12.7","Cell RNA - U-698 [nTPM]":"29.4","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"11.1","Blood RNA - basophil [nTPM]":"21.7","Blood RNA - classical monocyte [nTPM]":"6.7","Blood RNA - eosinophil [nTPM]":"12.1","Blood RNA - gdT-cell [nTPM]":"13.6","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"14.8","Blood RNA - memory B-cell [nTPM]":"12.6","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.7","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"8.5","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"17.9","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"6.0","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.5","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"22.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"26.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - dendritic cells [nTPM]":"19.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"13.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"32.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"62.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"16.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"12.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"10.6","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"4.9","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.2","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"34.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"IDI1","Gene synonym":[],"Ensembl":"ENSG00000067064","Gene description":"Isopentenyl-diphosphate delta isomerase 1","Uniprot":["Q13907"],"Chromosome":"10","Position":"1039152-1049119","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Isoprene biosynthesis","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039169"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039169":"AB_10674280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.2","Tissue RNA - adrenal gland [nTPM]":"93.7","Tissue RNA - amygdala [nTPM]":"36.9","Tissue RNA - appendix [nTPM]":"36.6","Tissue RNA - basal ganglia [nTPM]":"38.9","Tissue RNA - bone marrow [nTPM]":"133.9","Tissue RNA - breast [nTPM]":"152.1","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"44.2","Tissue RNA - cervix [nTPM]":"24.5","Tissue RNA - choroid plexus [nTPM]":"36.9","Tissue RNA - colon [nTPM]":"37.3","Tissue RNA - duodenum [nTPM]":"66.7","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"28.5","Tissue RNA - esophagus [nTPM]":"50.5","Tissue RNA - fallopian tube [nTPM]":"16.7","Tissue RNA - gallbladder [nTPM]":"21.9","Tissue RNA - heart muscle [nTPM]":"24.6","Tissue RNA - hippocampal formation [nTPM]":"39.9","Tissue RNA - hypothalamus [nTPM]":"46.8","Tissue RNA - kidney [nTPM]":"41.3","Tissue RNA - liver [nTPM]":"160.2","Tissue RNA - lung [nTPM]":"39.9","Tissue RNA - lymph node [nTPM]":"39.0","Tissue RNA - medulla oblongata [nTPM]":"49.4","Tissue RNA - midbrain [nTPM]":"46.9","Tissue RNA - ovary [nTPM]":"26.7","Tissue RNA - pancreas [nTPM]":"31.3","Tissue RNA - parathyroid gland [nTPM]":"25.9","Tissue RNA - pituitary gland [nTPM]":"43.9","Tissue RNA - placenta [nTPM]":"23.4","Tissue RNA - pons [nTPM]":"51.1","Tissue RNA - prostate [nTPM]":"50.2","Tissue RNA - rectum [nTPM]":"34.3","Tissue RNA - retina [nTPM]":"37.5","Tissue RNA - salivary gland [nTPM]":"26.3","Tissue RNA - seminal vesicle [nTPM]":"13.4","Tissue RNA - skeletal muscle [nTPM]":"105.9","Tissue RNA - skin 1 [nTPM]":"37.9","Tissue RNA - small intestine [nTPM]":"34.8","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"42.4","Tissue RNA - spleen [nTPM]":"44.0","Tissue RNA - stomach 1 [nTPM]":"37.2","Tissue RNA - testis [nTPM]":"25.3","Tissue RNA - thalamus [nTPM]":"44.0","Tissue RNA - thymus [nTPM]":"26.3","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"44.7","Tissue RNA - tonsil [nTPM]":"39.8","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"30.8","Tissue RNA - white matter [nTPM]":"47.0","Cell RNA - A-431 [nTPM]":"89.5","Cell RNA - A549 [nTPM]":"33.4","Cell RNA - AF22 [nTPM]":"173.4","Cell RNA - AN3-CA [nTPM]":"42.0","Cell RNA - ASC diff [nTPM]":"71.1","Cell RNA - ASC TERT1 [nTPM]":"154.1","Cell RNA - BEWO [nTPM]":"25.2","Cell RNA - BJ [nTPM]":"36.7","Cell RNA - BJ hTERT+ [nTPM]":"41.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"88.7","Cell RNA - CACO-2 [nTPM]":"89.6","Cell RNA - CAPAN-2 [nTPM]":"136.8","Cell RNA - Daudi [nTPM]":"80.9","Cell RNA - EFO-21 [nTPM]":"23.6","Cell RNA - fHDF\/TERT166 [nTPM]":"40.8","Cell RNA - GAMG [nTPM]":"101.7","Cell RNA - HaCaT [nTPM]":"75.8","Cell RNA - HAP1 [nTPM]":"97.8","Cell RNA - HBEC3-KT [nTPM]":"177.8","Cell RNA - HBF TERT88 [nTPM]":"38.3","Cell RNA - HDLM-2 [nTPM]":"27.9","Cell RNA - HEK 293 [nTPM]":"93.8","Cell RNA - HEL [nTPM]":"78.2","Cell RNA - HeLa [nTPM]":"50.1","Cell RNA - Hep G2 [nTPM]":"103.2","Cell RNA - HHSteC [nTPM]":"83.9","Cell RNA - HL-60 [nTPM]":"30.4","Cell RNA - HMC-1 [nTPM]":"37.5","Cell RNA - HSkMC [nTPM]":"99.3","Cell RNA - hTCEpi [nTPM]":"73.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"119.3","Cell RNA - hTERT-HME1 [nTPM]":"15.6","Cell RNA - hTERT-RPE1 [nTPM]":"18.1","Cell RNA - HUVEC TERT2 [nTPM]":"33.4","Cell RNA - JURKAT [nTPM]":"75.0","Cell RNA - K-562 [nTPM]":"54.5","Cell RNA - Karpas-707 [nTPM]":"111.1","Cell RNA - LHCN-M2 [nTPM]":"72.2","Cell RNA - MCF7 [nTPM]":"72.4","Cell RNA - MOLT-4 [nTPM]":"59.1","Cell RNA - NB-4 [nTPM]":"51.9","Cell RNA - NTERA-2 [nTPM]":"69.0","Cell RNA - OE19 [nTPM]":"74.6","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"67.2","Cell RNA - RH-30 [nTPM]":"82.0","Cell RNA - RPMI-8226 [nTPM]":"89.5","Cell RNA - RPTEC TERT1 [nTPM]":"185.7","Cell RNA - RT4 [nTPM]":"79.7","Cell RNA - SCLC-21H [nTPM]":"26.6","Cell RNA - SH-SY5Y [nTPM]":"31.6","Cell RNA - SiHa [nTPM]":"46.4","Cell RNA - SK-BR-3 [nTPM]":"96.5","Cell RNA - SK-MEL-30 [nTPM]":"100.7","Cell RNA - SuSa [nTPM]":"53.5","Cell RNA - T-47d [nTPM]":"99.3","Cell RNA - THP-1 [nTPM]":"103.8","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"22.7","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"66.8","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"64.3","Cell RNA - U-266\/84 [nTPM]":"64.7","Cell RNA - U-698 [nTPM]":"151.3","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"89.4","Cell RNA - WM-115 [nTPM]":"20.4","Blood RNA - basophil [nTPM]":"76.0","Blood RNA - classical monocyte [nTPM]":"15.1","Blood RNA - eosinophil [nTPM]":"37.6","Blood RNA - gdT-cell [nTPM]":"27.6","Blood RNA - intermediate monocyte [nTPM]":"28.3","Blood RNA - MAIT T-cell [nTPM]":"27.5","Blood RNA - memory B-cell [nTPM]":"25.8","Blood RNA - memory CD4 T-cell [nTPM]":"21.0","Blood RNA - memory CD8 T-cell [nTPM]":"22.7","Blood RNA - myeloid DC [nTPM]":"13.9","Blood RNA - naive B-cell [nTPM]":"26.0","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"22.6","Blood RNA - neutrophil [nTPM]":"41.4","Blood RNA - NK-cell [nTPM]":"24.2","Blood RNA - non-classical monocyte [nTPM]":"33.5","Blood RNA - plasmacytoid DC [nTPM]":"14.4","Blood RNA - T-reg [nTPM]":"24.8","Blood RNA - total PBMC [nTPM]":"26.6","Brain RNA - amygdala [nTPM]":"36.9","Brain RNA - basal ganglia [nTPM]":"38.9","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"44.2","Brain RNA - hippocampal formation [nTPM]":"39.9","Brain RNA - hypothalamus [nTPM]":"46.8","Brain RNA - medulla oblongata [nTPM]":"49.4","Brain RNA - midbrain [nTPM]":"46.9","Brain RNA - pons [nTPM]":"51.1","Brain RNA - spinal cord [nTPM]":"42.4","Brain RNA - thalamus [nTPM]":"44.0","Brain RNA - white matter [nTPM]":"47.0","Single Cell Type RNA - Adipocytes [nTPM]":"119.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"144.3","Single Cell Type RNA - Astrocytes [nTPM]":"53.8","Single Cell Type RNA - B-cells [nTPM]":"176.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"80.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"175.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.1","Single Cell Type RNA - Bipolar cells [nTPM]":"77.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"110.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"70.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"109.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.3","Single Cell Type RNA - dendritic cells [nTPM]":"233.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"167.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"150.6","Single Cell Type RNA - Ductal cells [nTPM]":"62.9","Single Cell Type RNA - Early spermatids [nTPM]":"277.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.6","Single Cell Type RNA - Endothelial cells [nTPM]":"64.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.0","Single Cell Type RNA - Erythroid cells [nTPM]":"31.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"102.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.6","Single Cell Type RNA - Fibroblasts [nTPM]":"62.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"108.2","Single Cell Type RNA - granulocytes [nTPM]":"100.7","Single Cell Type RNA - Granulosa cells [nTPM]":"60.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"67.1","Single Cell Type RNA - Hepatocytes [nTPM]":"322.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.9","Single Cell Type RNA - Horizontal cells [nTPM]":"63.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"107.6","Single Cell Type RNA - Ionocytes [nTPM]":"156.6","Single Cell Type RNA - Kupffer cells [nTPM]":"59.1","Single Cell Type RNA - Langerhans cells [nTPM]":"63.2","Single Cell Type RNA - Late spermatids [nTPM]":"101.5","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"88.8","Single Cell Type RNA - Melanocytes [nTPM]":"133.4","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"55.8","Single Cell Type RNA - Muller glia cells [nTPM]":"130.9","Single Cell Type RNA - NK-cells [nTPM]":"118.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.9","Single Cell Type RNA - Paneth cells [nTPM]":"130.9","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"60.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"116.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"70.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"63.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"70.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.4","Single Cell Type RNA - Spermatocytes [nTPM]":"82.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"79.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"144.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"187.2","Single Cell Type RNA - T-cells [nTPM]":"154.9","Single Cell Type RNA - Theca cells [nTPM]":"171.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.0","Single Cell Type RNA - Urothelial cells [nTPM]":"121.2"},{"Gene":"IDI2","Gene synonym":["IPPI2"],"Ensembl":"ENSG00000148377","Gene description":"Isopentenyl-diphosphate delta isomerase 2","Uniprot":["Q9BXS1"],"Chromosome":"10","Position":"1018910-1025859","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Isoprene biosynthesis","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skeletal muscle":"273.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"1.1","Glandular and luminal cells":"1.1","Horizontal cells":"1.7","Skeletal myocytes":"3.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041254"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041254":"AB_10794270"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"273.8","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"LIPA","Gene synonym":["CESD","LAL"],"Ensembl":"ENSG00000107798","Gene description":"Lipase A, lysosomal acid type","Uniprot":["P38571"],"Chromosome":"10","Position":"89213569-89414557","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"398.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"515.0","Kupffer cells":"714.8","Macrophages":"303.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"167.3","intermediate monocyte":"355.1","myeloid DC":"123.6","non-classical monocyte":"198.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"123.6","monocytes":"355.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"354.4","AN3-CA":"367.8","ASC TERT1":"450.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034892","HPA057052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli fibrillar center"],"Antibody RRID":{"CAB034892":"AB_784329","HPA057052":"AB_2683322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.0","Tissue RNA - adrenal gland [nTPM]":"46.3","Tissue RNA - amygdala [nTPM]":"43.5","Tissue RNA - appendix [nTPM]":"66.7","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"39.8","Tissue RNA - breast [nTPM]":"47.8","Tissue RNA - cerebellum [nTPM]":"64.1","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"54.0","Tissue RNA - choroid plexus [nTPM]":"39.0","Tissue RNA - colon [nTPM]":"67.7","Tissue RNA - duodenum [nTPM]":"167.6","Tissue RNA - endometrium 1 [nTPM]":"38.8","Tissue RNA - epididymis [nTPM]":"21.7","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"83.5","Tissue RNA - heart muscle [nTPM]":"24.2","Tissue RNA - hippocampal formation [nTPM]":"43.5","Tissue RNA - hypothalamus [nTPM]":"53.1","Tissue RNA - kidney [nTPM]":"44.9","Tissue RNA - liver [nTPM]":"218.9","Tissue RNA - lung [nTPM]":"169.5","Tissue RNA - lymph node [nTPM]":"159.3","Tissue RNA - medulla oblongata [nTPM]":"74.7","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"68.9","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"79.1","Tissue RNA - pons [nTPM]":"82.2","Tissue RNA - prostate [nTPM]":"30.7","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"22.5","Tissue RNA - seminal vesicle [nTPM]":"33.8","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"227.5","Tissue RNA - smooth muscle [nTPM]":"47.7","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"398.4","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"57.0","Tissue RNA - thymus [nTPM]":"44.5","Tissue RNA - thyroid gland [nTPM]":"31.6","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"45.5","Tissue RNA - urinary bladder [nTPM]":"58.4","Tissue RNA - vagina [nTPM]":"19.3","Tissue RNA - white matter [nTPM]":"115.5","Cell RNA - A-431 [nTPM]":"354.4","Cell RNA - A549 [nTPM]":"49.4","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"367.8","Cell RNA - ASC diff [nTPM]":"343.5","Cell RNA - ASC TERT1 [nTPM]":"450.8","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"171.4","Cell RNA - BJ hTERT+ [nTPM]":"194.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.5","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"176.6","Cell RNA - Daudi [nTPM]":"63.9","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"264.4","Cell RNA - GAMG [nTPM]":"73.7","Cell RNA - HaCaT [nTPM]":"338.7","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"92.8","Cell RNA - HBF TERT88 [nTPM]":"53.6","Cell RNA - HDLM-2 [nTPM]":"86.1","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"25.1","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"87.6","Cell RNA - HL-60 [nTPM]":"48.8","Cell RNA - HMC-1 [nTPM]":"48.9","Cell RNA - HSkMC [nTPM]":"190.4","Cell RNA - hTCEpi [nTPM]":"69.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"88.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"108.5","Cell RNA - LHCN-M2 [nTPM]":"58.3","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"45.7","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"62.4","Cell RNA - PC-3 [nTPM]":"60.0","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"39.0","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"69.2","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"49.9","Cell RNA - SK-MEL-30 [nTPM]":"133.9","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"64.4","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"132.1","Cell RNA - U-251 MG [nTPM]":"44.6","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"65.7","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"71.4","Cell RNA - U-937 [nTPM]":"112.9","Cell RNA - WM-115 [nTPM]":"82.1","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"167.3","Blood RNA - eosinophil [nTPM]":"16.9","Blood RNA - gdT-cell [nTPM]":"40.0","Blood RNA - intermediate monocyte [nTPM]":"355.1","Blood RNA - MAIT T-cell [nTPM]":"40.6","Blood RNA - memory B-cell [nTPM]":"31.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.8","Blood RNA - myeloid DC [nTPM]":"123.6","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"36.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.4","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"198.5","Blood RNA - plasmacytoid DC [nTPM]":"25.0","Blood RNA - T-reg [nTPM]":"38.2","Blood RNA - total PBMC [nTPM]":"159.6","Brain RNA - amygdala [nTPM]":"43.5","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"64.1","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"43.5","Brain RNA - hypothalamus [nTPM]":"53.1","Brain RNA - medulla oblongata [nTPM]":"74.7","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"82.2","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"57.0","Brain RNA - white matter [nTPM]":"115.5","Single Cell Type RNA - Adipocytes [nTPM]":"75.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"31.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"66.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"515.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"714.8","Single Cell Type RNA - Langerhans cells [nTPM]":"69.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"303.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"71.7","Single Cell Type RNA - Muller glia cells [nTPM]":"33.1","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"161.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"33.1","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"LSS","Gene synonym":["OSC"],"Ensembl":"ENSG00000160285","Gene description":"Lanosterol synthase","Uniprot":["P48449"],"Chromosome":"21","Position":"46188141-46228824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Hypotrichosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"132.0","Oligodendrocytes":"158.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"234.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032060","HPA032062","CAB034116"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034116":"AB_2138611","HPA032060":"AB_10671085","HPA032062":"AB_2674134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"38.9","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"28.5","Tissue RNA - endometrium 1 [nTPM]":"26.6","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"25.1","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"62.3","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"19.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"65.7","Tissue RNA - prostate [nTPM]":"24.0","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"29.0","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"28.4","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"40.4","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"58.7","Cell RNA - A-431 [nTPM]":"70.4","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"70.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"94.1","Cell RNA - ASC TERT1 [nTPM]":"90.6","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"186.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.7","Cell RNA - CACO-2 [nTPM]":"73.9","Cell RNA - CAPAN-2 [nTPM]":"54.4","Cell RNA - Daudi [nTPM]":"15.4","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"51.7","Cell RNA - GAMG [nTPM]":"234.6","Cell RNA - HaCaT [nTPM]":"32.7","Cell RNA - HAP1 [nTPM]":"63.2","Cell RNA - HBEC3-KT [nTPM]":"110.9","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"14.9","Cell RNA - HEK 293 [nTPM]":"34.5","Cell RNA - HEL [nTPM]":"37.7","Cell RNA - HeLa [nTPM]":"38.6","Cell RNA - Hep G2 [nTPM]":"48.3","Cell RNA - HHSteC [nTPM]":"85.5","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"89.0","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"72.1","Cell RNA - K-562 [nTPM]":"37.4","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"23.8","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"115.4","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"34.9","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"92.2","Cell RNA - RPTEC TERT1 [nTPM]":"82.8","Cell RNA - RT4 [nTPM]":"38.1","Cell RNA - SCLC-21H [nTPM]":"41.4","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"38.0","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"40.8","Cell RNA - U-138 MG [nTPM]":"37.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"31.8","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"30.6","Cell RNA - U-87 MG [nTPM]":"39.7","Cell RNA - U-937 [nTPM]":"59.4","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"62.3","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"65.7","Brain RNA - spinal cord [nTPM]":"28.4","Brain RNA - thalamus [nTPM]":"40.4","Brain RNA - white matter [nTPM]":"58.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"132.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"MSMO1","Gene synonym":["DESP4","ERG25","SC4MOL"],"Ensembl":"ENSG00000052802","Gene description":"Methylsterol monooxygenase 1","Uniprot":["Q15800"],"Chromosome":"4","Position":"165327667-165343164","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"575.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"532.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"416.2","Karpas-707":"412.3","RPTEC TERT1":"399.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055073","HPA056127"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA055073":null,"HPA056127":"AB_2683045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.3","Tissue RNA - adrenal gland [nTPM]":"95.2","Tissue RNA - amygdala [nTPM]":"36.7","Tissue RNA - appendix [nTPM]":"20.9","Tissue RNA - basal ganglia [nTPM]":"48.2","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"66.2","Tissue RNA - cerebellum [nTPM]":"45.1","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"57.1","Tissue RNA - choroid plexus [nTPM]":"37.4","Tissue RNA - colon [nTPM]":"39.2","Tissue RNA - duodenum [nTPM]":"75.7","Tissue RNA - endometrium 1 [nTPM]":"19.1","Tissue RNA - epididymis [nTPM]":"97.0","Tissue RNA - esophagus [nTPM]":"145.7","Tissue RNA - fallopian tube [nTPM]":"20.9","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"18.5","Tissue RNA - hippocampal formation [nTPM]":"43.9","Tissue RNA - hypothalamus [nTPM]":"59.2","Tissue RNA - kidney [nTPM]":"52.6","Tissue RNA - liver [nTPM]":"575.6","Tissue RNA - lung [nTPM]":"70.3","Tissue RNA - lymph node [nTPM]":"20.7","Tissue RNA - medulla oblongata [nTPM]":"90.5","Tissue RNA - midbrain [nTPM]":"58.4","Tissue RNA - ovary [nTPM]":"25.7","Tissue RNA - pancreas [nTPM]":"22.6","Tissue RNA - parathyroid gland [nTPM]":"42.9","Tissue RNA - pituitary gland [nTPM]":"18.4","Tissue RNA - placenta [nTPM]":"22.9","Tissue RNA - pons [nTPM]":"78.6","Tissue RNA - prostate [nTPM]":"58.9","Tissue RNA - rectum [nTPM]":"32.9","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"12.1","Tissue RNA - skeletal muscle [nTPM]":"5.5","Tissue RNA - skin 1 [nTPM]":"82.5","Tissue RNA - small intestine [nTPM]":"38.1","Tissue RNA - smooth muscle [nTPM]":"16.5","Tissue RNA - spinal cord [nTPM]":"45.0","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"31.5","Tissue RNA - testis [nTPM]":"52.8","Tissue RNA - thalamus [nTPM]":"48.4","Tissue RNA - thymus [nTPM]":"13.4","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"67.0","Tissue RNA - white matter [nTPM]":"61.1","Cell RNA - A-431 [nTPM]":"89.1","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"198.8","Cell RNA - AN3-CA [nTPM]":"36.4","Cell RNA - ASC diff [nTPM]":"97.7","Cell RNA - ASC TERT1 [nTPM]":"312.0","Cell RNA - BEWO [nTPM]":"37.5","Cell RNA - BJ [nTPM]":"35.3","Cell RNA - BJ hTERT+ [nTPM]":"159.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"123.4","Cell RNA - CACO-2 [nTPM]":"41.5","Cell RNA - CAPAN-2 [nTPM]":"372.9","Cell RNA - Daudi [nTPM]":"43.4","Cell RNA - EFO-21 [nTPM]":"20.6","Cell RNA - fHDF\/TERT166 [nTPM]":"43.1","Cell RNA - GAMG [nTPM]":"416.2","Cell RNA - HaCaT [nTPM]":"71.7","Cell RNA - HAP1 [nTPM]":"101.6","Cell RNA - HBEC3-KT [nTPM]":"366.3","Cell RNA - HBF TERT88 [nTPM]":"49.4","Cell RNA - HDLM-2 [nTPM]":"37.7","Cell RNA - HEK 293 [nTPM]":"63.0","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"20.0","Cell RNA - Hep G2 [nTPM]":"127.6","Cell RNA - HHSteC [nTPM]":"194.9","Cell RNA - HL-60 [nTPM]":"35.8","Cell RNA - HMC-1 [nTPM]":"26.8","Cell RNA - HSkMC [nTPM]":"192.6","Cell RNA - hTCEpi [nTPM]":"237.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"163.6","Cell RNA - hTERT-HME1 [nTPM]":"100.6","Cell RNA - hTERT-RPE1 [nTPM]":"61.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.8","Cell RNA - JURKAT [nTPM]":"55.7","Cell RNA - K-562 [nTPM]":"35.3","Cell RNA - Karpas-707 [nTPM]":"412.3","Cell RNA - LHCN-M2 [nTPM]":"74.6","Cell RNA - MCF7 [nTPM]":"45.7","Cell RNA - MOLT-4 [nTPM]":"32.6","Cell RNA - NB-4 [nTPM]":"58.2","Cell RNA - NTERA-2 [nTPM]":"115.6","Cell RNA - OE19 [nTPM]":"46.9","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"132.3","Cell RNA - RPTEC TERT1 [nTPM]":"399.5","Cell RNA - RT4 [nTPM]":"102.5","Cell RNA - SCLC-21H [nTPM]":"39.7","Cell RNA - SH-SY5Y [nTPM]":"30.0","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"77.9","Cell RNA - SK-MEL-30 [nTPM]":"33.9","Cell RNA - SuSa [nTPM]":"121.7","Cell RNA - T-47d [nTPM]":"36.1","Cell RNA - THP-1 [nTPM]":"44.7","Cell RNA - TIME [nTPM]":"67.6","Cell RNA - U-138 MG [nTPM]":"20.6","Cell RNA - U-2 OS [nTPM]":"36.1","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"24.7","Cell RNA - U-266\/70 [nTPM]":"75.9","Cell RNA - U-266\/84 [nTPM]":"86.5","Cell RNA - U-698 [nTPM]":"58.6","Cell RNA - U-87 MG [nTPM]":"43.9","Cell RNA - U-937 [nTPM]":"36.0","Cell RNA - WM-115 [nTPM]":"28.5","Blood RNA - basophil [nTPM]":"13.7","Blood RNA - classical monocyte [nTPM]":"8.6","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"34.0","Blood RNA - intermediate monocyte [nTPM]":"11.6","Blood RNA - MAIT T-cell [nTPM]":"25.4","Blood RNA - memory B-cell [nTPM]":"40.6","Blood RNA - memory CD4 T-cell [nTPM]":"31.8","Blood RNA - memory CD8 T-cell [nTPM]":"31.4","Blood RNA - myeloid DC [nTPM]":"15.0","Blood RNA - naive B-cell [nTPM]":"37.6","Blood RNA - naive CD4 T-cell [nTPM]":"34.3","Blood RNA - naive CD8 T-cell [nTPM]":"35.6","Blood RNA - neutrophil [nTPM]":"6.1","Blood RNA - NK-cell [nTPM]":"24.9","Blood RNA - non-classical monocyte [nTPM]":"20.5","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"31.0","Blood RNA - total PBMC [nTPM]":"29.2","Brain RNA - amygdala [nTPM]":"36.7","Brain RNA - basal ganglia [nTPM]":"48.2","Brain RNA - cerebellum [nTPM]":"45.1","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"43.9","Brain RNA - hypothalamus [nTPM]":"59.2","Brain RNA - medulla oblongata [nTPM]":"90.5","Brain RNA - midbrain [nTPM]":"58.4","Brain RNA - pons [nTPM]":"78.6","Brain RNA - spinal cord [nTPM]":"45.0","Brain RNA - thalamus [nTPM]":"48.4","Brain RNA - white matter [nTPM]":"61.1","Single Cell Type RNA - Adipocytes [nTPM]":"16.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"168.0","Single Cell Type RNA - Astrocytes [nTPM]":"70.5","Single Cell Type RNA - B-cells [nTPM]":"28.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"36.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"189.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"33.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"160.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"130.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"67.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"30.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"60.7","Single Cell Type RNA - Erythroid cells [nTPM]":"53.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"87.0","Single Cell Type RNA - Fibroblasts [nTPM]":"24.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.4","Single Cell Type RNA - granulocytes [nTPM]":"47.7","Single Cell Type RNA - Granulosa cells [nTPM]":"83.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"532.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"72.8","Single Cell Type RNA - Ionocytes [nTPM]":"170.9","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"18.3","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"23.6","Single Cell Type RNA - Muller glia cells [nTPM]":"27.2","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"42.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"86.8","Single Cell Type RNA - Paneth cells [nTPM]":"85.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"138.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"103.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"115.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"123.0","Single Cell Type RNA - T-cells [nTPM]":"22.3","Single Cell Type RNA - Theca cells [nTPM]":"136.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.9","Single Cell Type RNA - Urothelial cells [nTPM]":"129.0"},{"Gene":"MVD","Gene synonym":["MPD"],"Ensembl":"ENSG00000167508","Gene description":"Mevalonate diphosphate decarboxylase","Uniprot":["P53602"],"Chromosome":"16","Position":"88651935-88663161","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"147.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041404","HPA048250"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041404":"AB_2677457","HPA048250":"AB_2680329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.3","Tissue RNA - adrenal gland [nTPM]":"51.1","Tissue RNA - amygdala [nTPM]":"24.2","Tissue RNA - appendix [nTPM]":"15.7","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"7.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"26.2","Tissue RNA - cerebral cortex [nTPM]":"37.5","Tissue RNA - cervix [nTPM]":"30.5","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"32.3","Tissue RNA - duodenum [nTPM]":"35.1","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"77.8","Tissue RNA - fallopian tube [nTPM]":"13.5","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"24.7","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"28.8","Tissue RNA - liver [nTPM]":"78.8","Tissue RNA - lung [nTPM]":"31.0","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"32.4","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"25.3","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"18.9","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"39.3","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"25.1","Tissue RNA - seminal vesicle [nTPM]":"6.5","Tissue RNA - skeletal muscle [nTPM]":"27.2","Tissue RNA - skin 1 [nTPM]":"52.3","Tissue RNA - small intestine [nTPM]":"26.6","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"24.0","Tissue RNA - spleen [nTPM]":"24.6","Tissue RNA - stomach 1 [nTPM]":"31.5","Tissue RNA - testis [nTPM]":"42.3","Tissue RNA - thalamus [nTPM]":"24.7","Tissue RNA - thymus [nTPM]":"7.0","Tissue RNA - thyroid gland [nTPM]":"21.1","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"36.9","Tissue RNA - white matter [nTPM]":"25.6","Cell RNA - A-431 [nTPM]":"50.6","Cell RNA - A549 [nTPM]":"34.2","Cell RNA - AF22 [nTPM]":"52.4","Cell RNA - AN3-CA [nTPM]":"33.1","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"38.7","Cell RNA - BEWO [nTPM]":"29.5","Cell RNA - BJ [nTPM]":"25.1","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.6","Cell RNA - CACO-2 [nTPM]":"86.1","Cell RNA - CAPAN-2 [nTPM]":"119.7","Cell RNA - Daudi [nTPM]":"24.4","Cell RNA - EFO-21 [nTPM]":"39.8","Cell RNA - fHDF\/TERT166 [nTPM]":"15.7","Cell RNA - GAMG [nTPM]":"63.7","Cell RNA - HaCaT [nTPM]":"72.8","Cell RNA - HAP1 [nTPM]":"25.0","Cell RNA - HBEC3-KT [nTPM]":"133.1","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"15.7","Cell RNA - HEK 293 [nTPM]":"38.3","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"18.2","Cell RNA - Hep G2 [nTPM]":"127.0","Cell RNA - HHSteC [nTPM]":"35.9","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"30.9","Cell RNA - hTCEpi [nTPM]":"24.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.6","Cell RNA - hTERT-HME1 [nTPM]":"13.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"58.0","Cell RNA - K-562 [nTPM]":"51.7","Cell RNA - Karpas-707 [nTPM]":"13.1","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"115.9","Cell RNA - MOLT-4 [nTPM]":"39.3","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"61.5","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"31.3","Cell RNA - REH [nTPM]":"40.2","Cell RNA - RH-30 [nTPM]":"15.0","Cell RNA - RPMI-8226 [nTPM]":"62.3","Cell RNA - RPTEC TERT1 [nTPM]":"49.8","Cell RNA - RT4 [nTPM]":"33.0","Cell RNA - SCLC-21H [nTPM]":"52.2","Cell RNA - SH-SY5Y [nTPM]":"17.9","Cell RNA - SiHa [nTPM]":"62.0","Cell RNA - SK-BR-3 [nTPM]":"13.3","Cell RNA - SK-MEL-30 [nTPM]":"18.5","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"67.8","Cell RNA - THP-1 [nTPM]":"51.3","Cell RNA - TIME [nTPM]":"39.0","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"29.8","Cell RNA - U-2197 [nTPM]":"27.2","Cell RNA - U-251 MG [nTPM]":"14.2","Cell RNA - U-266\/70 [nTPM]":"34.9","Cell RNA - U-266\/84 [nTPM]":"17.6","Cell RNA - U-698 [nTPM]":"83.2","Cell RNA - U-87 MG [nTPM]":"17.9","Cell RNA - U-937 [nTPM]":"55.7","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"26.8","Blood RNA - intermediate monocyte [nTPM]":"13.7","Blood RNA - MAIT T-cell [nTPM]":"20.4","Blood RNA - memory B-cell [nTPM]":"16.1","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"17.9","Blood RNA - myeloid DC [nTPM]":"15.0","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"13.2","Blood RNA - naive CD8 T-cell [nTPM]":"16.6","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"28.3","Blood RNA - non-classical monocyte [nTPM]":"15.4","Blood RNA - plasmacytoid DC [nTPM]":"28.0","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"15.4","Brain RNA - amygdala [nTPM]":"24.2","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"26.2","Brain RNA - cerebral cortex [nTPM]":"37.5","Brain RNA - hippocampal formation [nTPM]":"24.7","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"32.4","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"39.3","Brain RNA - spinal cord [nTPM]":"24.0","Brain RNA - thalamus [nTPM]":"24.7","Brain RNA - white matter [nTPM]":"25.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.2","Single Cell Type RNA - Astrocytes [nTPM]":"22.2","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"106.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"27.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"56.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"79.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"117.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"30.8","Single Cell Type RNA - Early spermatids [nTPM]":"61.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.9","Single Cell Type RNA - Erythroid cells [nTPM]":"26.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"15.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.5","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"147.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"75.3","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"25.5","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"96.2","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"32.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.0","Single Cell Type RNA - Paneth cells [nTPM]":"79.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"46.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.7","Single Cell Type RNA - Spermatocytes [nTPM]":"50.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.8","Single Cell Type RNA - T-cells [nTPM]":"36.3","Single Cell Type RNA - Theca cells [nTPM]":"35.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.2","Single Cell Type RNA - Urothelial cells [nTPM]":"20.6"},{"Gene":"MVK","Gene synonym":["LRBP","MK"],"Ensembl":"ENSG00000110921","Gene description":"Mevalonate kinase","Uniprot":["Q03426"],"Chromosome":"12","Position":"109573255-109598125","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"69.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"60.5","Horizontal cells":"62.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016961","HPA044110"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016961":"AB_1854220","HPA044110":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"29.8","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"11.2","Tissue RNA - duodenum [nTPM]":"13.9","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"45.5","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"13.2","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"69.1","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"36.1","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"10.7","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"38.6","Tissue RNA - prostate [nTPM]":"12.3","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"5.0","Tissue RNA - spinal cord [nTPM]":"15.3","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"28.5","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"15.1","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"9.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"24.4","Cell RNA - A-431 [nTPM]":"30.1","Cell RNA - A549 [nTPM]":"25.0","Cell RNA - AF22 [nTPM]":"29.9","Cell RNA - AN3-CA [nTPM]":"13.7","Cell RNA - ASC diff [nTPM]":"11.2","Cell RNA - ASC TERT1 [nTPM]":"27.3","Cell RNA - BEWO [nTPM]":"14.4","Cell RNA - BJ [nTPM]":"9.5","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.8","Cell RNA - CACO-2 [nTPM]":"31.4","Cell RNA - CAPAN-2 [nTPM]":"33.8","Cell RNA - Daudi [nTPM]":"17.7","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"48.1","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"50.0","Cell RNA - HBF TERT88 [nTPM]":"13.2","Cell RNA - HDLM-2 [nTPM]":"19.0","Cell RNA - HEK 293 [nTPM]":"18.1","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"15.7","Cell RNA - Hep G2 [nTPM]":"53.7","Cell RNA - HHSteC [nTPM]":"31.5","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"27.2","Cell RNA - hTCEpi [nTPM]":"42.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.8","Cell RNA - hTERT-HME1 [nTPM]":"13.6","Cell RNA - hTERT-RPE1 [nTPM]":"12.6","Cell RNA - HUVEC TERT2 [nTPM]":"20.9","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"18.7","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"13.6","Cell RNA - MCF7 [nTPM]":"34.5","Cell RNA - MOLT-4 [nTPM]":"12.0","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"14.9","Cell RNA - PC-3 [nTPM]":"32.3","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"22.1","Cell RNA - RPMI-8226 [nTPM]":"37.0","Cell RNA - RPTEC TERT1 [nTPM]":"67.4","Cell RNA - RT4 [nTPM]":"40.9","Cell RNA - SCLC-21H [nTPM]":"25.1","Cell RNA - SH-SY5Y [nTPM]":"18.7","Cell RNA - SiHa [nTPM]":"19.8","Cell RNA - SK-BR-3 [nTPM]":"58.7","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"59.7","Cell RNA - THP-1 [nTPM]":"21.1","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"13.2","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"13.3","Cell RNA - U-266\/84 [nTPM]":"20.6","Cell RNA - U-698 [nTPM]":"28.2","Cell RNA - U-87 MG [nTPM]":"16.1","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"6.9","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"12.6","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"11.3","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.4","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"8.6","Blood RNA - naive B-cell [nTPM]":"14.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.9","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"13.2","Brain RNA - medulla oblongata [nTPM]":"36.1","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"38.6","Brain RNA - spinal cord [nTPM]":"15.3","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"24.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"25.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"15.6","Single Cell Type RNA - Early spermatids [nTPM]":"60.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"32.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"42.5","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"33.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"44.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"NSDHL","Gene synonym":["H105e3","SDR31E1","XAP104"],"Ensembl":"ENSG00000147383","Gene description":"NAD(P) dependent steroid dehydrogenase-like","Uniprot":["Q15738"],"Chromosome":"X","Position":"152830967-152869729","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"53.0","Hepatocytes":"55.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000248","HPA000571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA000248":"AB_1079507","HPA000571":"AB_1079506"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.0","Tissue RNA - adrenal gland [nTPM]":"38.8","Tissue RNA - amygdala [nTPM]":"13.2","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"20.2","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"20.3","Tissue RNA - choroid plexus [nTPM]":"13.7","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"17.6","Tissue RNA - endometrium 1 [nTPM]":"13.6","Tissue RNA - epididymis [nTPM]":"44.5","Tissue RNA - esophagus [nTPM]":"51.7","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"22.4","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"14.3","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"50.4","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"16.8","Tissue RNA - midbrain [nTPM]":"15.4","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"10.6","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"14.8","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"10.4","Tissue RNA - salivary gland [nTPM]":"16.7","Tissue RNA - seminal vesicle [nTPM]":"21.3","Tissue RNA - skeletal muscle [nTPM]":"10.1","Tissue RNA - skin 1 [nTPM]":"22.6","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"13.4","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"13.3","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"12.1","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"135.6","Cell RNA - A549 [nTPM]":"48.9","Cell RNA - AF22 [nTPM]":"65.5","Cell RNA - AN3-CA [nTPM]":"33.8","Cell RNA - ASC diff [nTPM]":"54.9","Cell RNA - ASC TERT1 [nTPM]":"41.5","Cell RNA - BEWO [nTPM]":"36.2","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.3","Cell RNA - CACO-2 [nTPM]":"68.5","Cell RNA - CAPAN-2 [nTPM]":"71.7","Cell RNA - Daudi [nTPM]":"67.0","Cell RNA - EFO-21 [nTPM]":"86.0","Cell RNA - fHDF\/TERT166 [nTPM]":"35.9","Cell RNA - GAMG [nTPM]":"174.2","Cell RNA - HaCaT [nTPM]":"67.6","Cell RNA - HAP1 [nTPM]":"85.5","Cell RNA - HBEC3-KT [nTPM]":"122.1","Cell RNA - HBF TERT88 [nTPM]":"41.3","Cell RNA - HDLM-2 [nTPM]":"22.0","Cell RNA - HEK 293 [nTPM]":"49.5","Cell RNA - HEL [nTPM]":"27.9","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"70.3","Cell RNA - HHSteC [nTPM]":"39.8","Cell RNA - HL-60 [nTPM]":"27.6","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"46.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.2","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.2","Cell RNA - HUVEC TERT2 [nTPM]":"44.2","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"46.4","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"36.1","Cell RNA - MCF7 [nTPM]":"60.1","Cell RNA - MOLT-4 [nTPM]":"27.3","Cell RNA - NB-4 [nTPM]":"35.8","Cell RNA - NTERA-2 [nTPM]":"26.0","Cell RNA - OE19 [nTPM]":"67.4","Cell RNA - PC-3 [nTPM]":"58.1","Cell RNA - REH [nTPM]":"19.9","Cell RNA - RH-30 [nTPM]":"47.4","Cell RNA - RPMI-8226 [nTPM]":"54.6","Cell RNA - RPTEC TERT1 [nTPM]":"98.9","Cell RNA - RT4 [nTPM]":"55.7","Cell RNA - SCLC-21H [nTPM]":"23.4","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"34.6","Cell RNA - SK-MEL-30 [nTPM]":"28.4","Cell RNA - SuSa [nTPM]":"44.9","Cell RNA - T-47d [nTPM]":"23.1","Cell RNA - THP-1 [nTPM]":"35.0","Cell RNA - TIME [nTPM]":"38.7","Cell RNA - U-138 MG [nTPM]":"21.6","Cell RNA - U-2 OS [nTPM]":"35.4","Cell RNA - U-2197 [nTPM]":"52.3","Cell RNA - U-251 MG [nTPM]":"51.0","Cell RNA - U-266\/70 [nTPM]":"40.9","Cell RNA - U-266\/84 [nTPM]":"29.4","Cell RNA - U-698 [nTPM]":"114.9","Cell RNA - U-87 MG [nTPM]":"40.0","Cell RNA - U-937 [nTPM]":"42.4","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"21.0","Blood RNA - classical monocyte [nTPM]":"19.6","Blood RNA - eosinophil [nTPM]":"18.7","Blood RNA - gdT-cell [nTPM]":"16.3","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"16.4","Blood RNA - memory B-cell [nTPM]":"19.1","Blood RNA - memory CD4 T-cell [nTPM]":"16.1","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"19.4","Blood RNA - naive B-cell [nTPM]":"15.1","Blood RNA - naive CD4 T-cell [nTPM]":"11.6","Blood RNA - naive CD8 T-cell [nTPM]":"12.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"19.7","Blood RNA - non-classical monocyte [nTPM]":"14.2","Blood RNA - plasmacytoid DC [nTPM]":"17.4","Blood RNA - T-reg [nTPM]":"20.4","Blood RNA - total PBMC [nTPM]":"15.2","Brain RNA - amygdala [nTPM]":"13.2","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"14.3","Brain RNA - medulla oblongata [nTPM]":"16.8","Brain RNA - midbrain [nTPM]":"15.4","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"13.4","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.7","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"29.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"20.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"14.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"55.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"9.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"25.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"16.4"},{"Gene":"PMVK","Gene synonym":["HUMPMKI","PMK","PMKA"],"Ensembl":"ENSG00000163344","Gene description":"Phosphomevalonate kinase","Uniprot":["Q15126"],"Chromosome":"1","Position":"154924740-154936719","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"266.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029900"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029900":"AB_10601390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.70e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"39.9","Tissue RNA - adrenal gland [nTPM]":"56.4","Tissue RNA - amygdala [nTPM]":"99.0","Tissue RNA - appendix [nTPM]":"29.8","Tissue RNA - basal ganglia [nTPM]":"100.1","Tissue RNA - bone marrow [nTPM]":"15.3","Tissue RNA - breast [nTPM]":"35.0","Tissue RNA - cerebellum [nTPM]":"97.9","Tissue RNA - cerebral cortex [nTPM]":"108.9","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"95.0","Tissue RNA - colon [nTPM]":"39.9","Tissue RNA - duodenum [nTPM]":"45.9","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"17.7","Tissue RNA - esophagus [nTPM]":"77.7","Tissue RNA - fallopian tube [nTPM]":"37.2","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"63.1","Tissue RNA - hippocampal formation [nTPM]":"93.9","Tissue RNA - hypothalamus [nTPM]":"96.4","Tissue RNA - kidney [nTPM]":"53.8","Tissue RNA - liver [nTPM]":"91.9","Tissue RNA - lung [nTPM]":"30.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"98.6","Tissue RNA - midbrain [nTPM]":"97.4","Tissue RNA - ovary [nTPM]":"35.8","Tissue RNA - pancreas [nTPM]":"41.6","Tissue RNA - parathyroid gland [nTPM]":"58.2","Tissue RNA - pituitary gland [nTPM]":"60.3","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"96.0","Tissue RNA - prostate [nTPM]":"32.4","Tissue RNA - rectum [nTPM]":"22.2","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"34.0","Tissue RNA - seminal vesicle [nTPM]":"27.1","Tissue RNA - skeletal muscle [nTPM]":"79.1","Tissue RNA - skin 1 [nTPM]":"69.2","Tissue RNA - small intestine [nTPM]":"44.2","Tissue RNA - smooth muscle [nTPM]":"27.7","Tissue RNA - spinal cord [nTPM]":"96.4","Tissue RNA - spleen [nTPM]":"45.7","Tissue RNA - stomach 1 [nTPM]":"40.5","Tissue RNA - testis [nTPM]":"26.6","Tissue RNA - thalamus [nTPM]":"102.3","Tissue RNA - thymus [nTPM]":"27.9","Tissue RNA - thyroid gland [nTPM]":"31.5","Tissue RNA - tongue [nTPM]":"47.4","Tissue RNA - tonsil [nTPM]":"36.8","Tissue RNA - urinary bladder [nTPM]":"31.9","Tissue RNA - vagina [nTPM]":"37.9","Tissue RNA - white matter [nTPM]":"99.8","Cell RNA - A-431 [nTPM]":"51.8","Cell RNA - A549 [nTPM]":"72.9","Cell RNA - AF22 [nTPM]":"46.7","Cell RNA - AN3-CA [nTPM]":"72.5","Cell RNA - ASC diff [nTPM]":"43.6","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"48.5","Cell RNA - BJ [nTPM]":"40.5","Cell RNA - BJ hTERT+ [nTPM]":"29.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.0","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"101.0","Cell RNA - Daudi [nTPM]":"75.1","Cell RNA - EFO-21 [nTPM]":"75.9","Cell RNA - fHDF\/TERT166 [nTPM]":"49.3","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"49.4","Cell RNA - HAP1 [nTPM]":"65.3","Cell RNA - HBEC3-KT [nTPM]":"63.9","Cell RNA - HBF TERT88 [nTPM]":"17.8","Cell RNA - HDLM-2 [nTPM]":"103.3","Cell RNA - HEK 293 [nTPM]":"28.9","Cell RNA - HEL [nTPM]":"34.1","Cell RNA - HeLa [nTPM]":"104.1","Cell RNA - Hep G2 [nTPM]":"29.0","Cell RNA - HHSteC [nTPM]":"40.0","Cell RNA - HL-60 [nTPM]":"51.4","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"36.3","Cell RNA - hTCEpi [nTPM]":"58.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.2","Cell RNA - hTERT-HME1 [nTPM]":"49.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.5","Cell RNA - HUVEC TERT2 [nTPM]":"40.0","Cell RNA - JURKAT [nTPM]":"65.9","Cell RNA - K-562 [nTPM]":"36.8","Cell RNA - Karpas-707 [nTPM]":"221.7","Cell RNA - LHCN-M2 [nTPM]":"41.3","Cell RNA - MCF7 [nTPM]":"108.3","Cell RNA - MOLT-4 [nTPM]":"40.8","Cell RNA - NB-4 [nTPM]":"51.0","Cell RNA - NTERA-2 [nTPM]":"41.0","Cell RNA - OE19 [nTPM]":"121.7","Cell RNA - PC-3 [nTPM]":"95.0","Cell RNA - REH [nTPM]":"60.3","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"171.1","Cell RNA - RPTEC TERT1 [nTPM]":"66.1","Cell RNA - RT4 [nTPM]":"38.4","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"91.1","Cell RNA - SiHa [nTPM]":"44.1","Cell RNA - SK-BR-3 [nTPM]":"75.7","Cell RNA - SK-MEL-30 [nTPM]":"51.9","Cell RNA - SuSa [nTPM]":"35.0","Cell RNA - T-47d [nTPM]":"146.7","Cell RNA - THP-1 [nTPM]":"91.1","Cell RNA - TIME [nTPM]":"32.7","Cell RNA - U-138 MG [nTPM]":"35.8","Cell RNA - U-2 OS [nTPM]":"29.2","Cell RNA - U-2197 [nTPM]":"84.4","Cell RNA - U-251 MG [nTPM]":"62.1","Cell RNA - U-266\/70 [nTPM]":"174.0","Cell RNA - U-266\/84 [nTPM]":"153.2","Cell RNA - U-698 [nTPM]":"131.8","Cell RNA - U-87 MG [nTPM]":"58.9","Cell RNA - U-937 [nTPM]":"83.9","Cell RNA - WM-115 [nTPM]":"46.7","Blood RNA - basophil [nTPM]":"28.0","Blood RNA - classical monocyte [nTPM]":"80.9","Blood RNA - eosinophil [nTPM]":"91.8","Blood RNA - gdT-cell [nTPM]":"68.2","Blood RNA - intermediate monocyte [nTPM]":"205.6","Blood RNA - MAIT T-cell [nTPM]":"110.1","Blood RNA - memory B-cell [nTPM]":"114.8","Blood RNA - memory CD4 T-cell [nTPM]":"93.1","Blood RNA - memory CD8 T-cell [nTPM]":"70.6","Blood RNA - myeloid DC [nTPM]":"93.6","Blood RNA - naive B-cell [nTPM]":"111.1","Blood RNA - naive CD4 T-cell [nTPM]":"59.1","Blood RNA - naive CD8 T-cell [nTPM]":"59.1","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"59.7","Blood RNA - non-classical monocyte [nTPM]":"219.4","Blood RNA - plasmacytoid DC [nTPM]":"96.5","Blood RNA - T-reg [nTPM]":"134.3","Blood RNA - total PBMC [nTPM]":"80.0","Brain RNA - amygdala [nTPM]":"99.0","Brain RNA - basal ganglia [nTPM]":"100.1","Brain RNA - cerebellum [nTPM]":"97.9","Brain RNA - cerebral cortex [nTPM]":"108.9","Brain RNA - hippocampal formation [nTPM]":"93.9","Brain RNA - hypothalamus [nTPM]":"96.4","Brain RNA - medulla oblongata [nTPM]":"98.6","Brain RNA - midbrain [nTPM]":"97.4","Brain RNA - pons [nTPM]":"96.0","Brain RNA - spinal cord [nTPM]":"96.4","Brain RNA - thalamus [nTPM]":"102.3","Brain RNA - white matter [nTPM]":"99.8","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"42.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"69.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"95.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"38.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"68.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"57.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"42.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"235.7","Single Cell Type RNA - dendritic cells [nTPM]":"31.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"266.1","Single Cell Type RNA - Ductal cells [nTPM]":"69.6","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"29.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"35.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"108.1","Single Cell Type RNA - Fibroblasts [nTPM]":"45.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"44.2","Single Cell Type RNA - granulocytes [nTPM]":"22.2","Single Cell Type RNA - Granulosa cells [nTPM]":"49.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.3","Single Cell Type RNA - Hepatocytes [nTPM]":"146.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"141.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.9","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"67.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.5","Single Cell Type RNA - Late spermatids [nTPM]":"13.5","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"47.8","Single Cell Type RNA - Melanocytes [nTPM]":"65.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"49.5","Single Cell Type RNA - Muller glia cells [nTPM]":"119.1","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.7","Single Cell Type RNA - Paneth cells [nTPM]":"61.7","Single Cell Type RNA - Peritubular cells [nTPM]":"47.8","Single Cell Type RNA - Plasma cells [nTPM]":"58.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"219.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"246.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.4","Single Cell Type RNA - Spermatocytes [nTPM]":"51.3","Single Cell Type RNA - Spermatogonia [nTPM]":"51.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"81.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"227.7","Single Cell Type RNA - T-cells [nTPM]":"45.1","Single Cell Type RNA - Theca cells [nTPM]":"162.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"79.9","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"SC5D","Gene synonym":["SC5DL"],"Ensembl":"ENSG00000109929","Gene description":"Sterol-C5-desaturase","Uniprot":["O75845"],"Chromosome":"11","Position":"121292681-121313410","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"393.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"141.0","Hepatocytes":"307.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066283","HPA070248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA066283":"AB_2685648","HPA070248":"AB_2686240"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.6","Tissue RNA - adrenal gland [nTPM]":"35.3","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"56.6","Tissue RNA - cerebellum [nTPM]":"37.1","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"20.7","Tissue RNA - choroid plexus [nTPM]":"17.6","Tissue RNA - colon [nTPM]":"23.2","Tissue RNA - duodenum [nTPM]":"48.2","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"73.2","Tissue RNA - esophagus [nTPM]":"39.6","Tissue RNA - fallopian tube [nTPM]":"16.5","Tissue RNA - gallbladder [nTPM]":"18.2","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"19.9","Tissue RNA - hypothalamus [nTPM]":"29.9","Tissue RNA - kidney [nTPM]":"49.1","Tissue RNA - liver [nTPM]":"393.6","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"42.9","Tissue RNA - midbrain [nTPM]":"28.0","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"21.5","Tissue RNA - parathyroid gland [nTPM]":"48.6","Tissue RNA - pituitary gland [nTPM]":"15.6","Tissue RNA - placenta [nTPM]":"14.7","Tissue RNA - pons [nTPM]":"39.1","Tissue RNA - prostate [nTPM]":"101.4","Tissue RNA - rectum [nTPM]":"19.9","Tissue RNA - retina [nTPM]":"29.5","Tissue RNA - salivary gland [nTPM]":"22.4","Tissue RNA - seminal vesicle [nTPM]":"56.6","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"24.7","Tissue RNA - smooth muscle [nTPM]":"16.2","Tissue RNA - spinal cord [nTPM]":"32.2","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"21.7","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"24.6","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"19.5","Tissue RNA - urinary bladder [nTPM]":"21.5","Tissue RNA - vagina [nTPM]":"27.1","Tissue RNA - white matter [nTPM]":"36.5","Cell RNA - A-431 [nTPM]":"26.5","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"184.8","Cell RNA - AN3-CA [nTPM]":"39.5","Cell RNA - ASC diff [nTPM]":"72.1","Cell RNA - ASC TERT1 [nTPM]":"59.9","Cell RNA - BEWO [nTPM]":"27.8","Cell RNA - BJ [nTPM]":"27.8","Cell RNA - BJ hTERT+ [nTPM]":"53.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"83.1","Cell RNA - CAPAN-2 [nTPM]":"95.9","Cell RNA - Daudi [nTPM]":"25.4","Cell RNA - EFO-21 [nTPM]":"89.0","Cell RNA - fHDF\/TERT166 [nTPM]":"32.3","Cell RNA - GAMG [nTPM]":"156.6","Cell RNA - HaCaT [nTPM]":"100.8","Cell RNA - HAP1 [nTPM]":"59.2","Cell RNA - HBEC3-KT [nTPM]":"70.9","Cell RNA - HBF TERT88 [nTPM]":"18.1","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"80.0","Cell RNA - HEL [nTPM]":"34.6","Cell RNA - HeLa [nTPM]":"73.4","Cell RNA - Hep G2 [nTPM]":"64.4","Cell RNA - HHSteC [nTPM]":"57.9","Cell RNA - HL-60 [nTPM]":"24.8","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"51.0","Cell RNA - hTCEpi [nTPM]":"57.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.4","Cell RNA - hTERT-HME1 [nTPM]":"60.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.8","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"25.0","Cell RNA - Karpas-707 [nTPM]":"34.6","Cell RNA - LHCN-M2 [nTPM]":"89.0","Cell RNA - MCF7 [nTPM]":"27.4","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"29.2","Cell RNA - NTERA-2 [nTPM]":"59.8","Cell RNA - OE19 [nTPM]":"74.4","Cell RNA - PC-3 [nTPM]":"39.7","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"51.0","Cell RNA - RPMI-8226 [nTPM]":"21.6","Cell RNA - RPTEC TERT1 [nTPM]":"133.6","Cell RNA - RT4 [nTPM]":"116.5","Cell RNA - SCLC-21H [nTPM]":"51.1","Cell RNA - SH-SY5Y [nTPM]":"28.8","Cell RNA - SiHa [nTPM]":"73.4","Cell RNA - SK-BR-3 [nTPM]":"14.6","Cell RNA - SK-MEL-30 [nTPM]":"38.0","Cell RNA - SuSa [nTPM]":"125.4","Cell RNA - T-47d [nTPM]":"62.2","Cell RNA - THP-1 [nTPM]":"38.6","Cell RNA - TIME [nTPM]":"58.3","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"29.7","Cell RNA - U-2197 [nTPM]":"32.5","Cell RNA - U-251 MG [nTPM]":"14.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"11.2","Cell RNA - U-698 [nTPM]":"33.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"49.5","Cell RNA - WM-115 [nTPM]":"33.5","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.5","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"4.2","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"37.1","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"19.9","Brain RNA - hypothalamus [nTPM]":"29.9","Brain RNA - medulla oblongata [nTPM]":"42.9","Brain RNA - midbrain [nTPM]":"28.0","Brain RNA - pons [nTPM]":"39.1","Brain RNA - spinal cord [nTPM]":"32.2","Brain RNA - thalamus [nTPM]":"24.6","Brain RNA - white matter [nTPM]":"36.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"62.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"40.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"47.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.6","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"141.0","Single Cell Type RNA - Hepatocytes [nTPM]":"307.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.0","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.3","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"17.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"38.7","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.8","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"20.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - T-cells [nTPM]":"56.5","Single Cell Type RNA - Theca cells [nTPM]":"42.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.3","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"SQLE","Gene synonym":[],"Ensembl":"ENSG00000104549","Gene description":"Squalene epoxidase","Uniprot":["Q14534"],"Chromosome":"8","Position":"124998497-125022283","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018038","HPA020762"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018038":"AB_2669753","HPA020762":"AB_2670512"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.42e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"31.1","Tissue RNA - amygdala [nTPM]":"17.5","Tissue RNA - appendix [nTPM]":"19.6","Tissue RNA - basal ganglia [nTPM]":"27.0","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"22.1","Tissue RNA - cerebellum [nTPM]":"26.8","Tissue RNA - cerebral cortex [nTPM]":"24.0","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"25.4","Tissue RNA - colon [nTPM]":"21.6","Tissue RNA - duodenum [nTPM]":"31.0","Tissue RNA - endometrium 1 [nTPM]":"16.4","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"78.7","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"18.6","Tissue RNA - hypothalamus [nTPM]":"24.4","Tissue RNA - kidney [nTPM]":"17.1","Tissue RNA - liver [nTPM]":"72.3","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"47.3","Tissue RNA - midbrain [nTPM]":"27.7","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"47.5","Tissue RNA - pons [nTPM]":"35.1","Tissue RNA - prostate [nTPM]":"25.0","Tissue RNA - rectum [nTPM]":"18.6","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"19.1","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"49.4","Tissue RNA - small intestine [nTPM]":"14.0","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"27.6","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"59.4","Tissue RNA - thalamus [nTPM]":"21.8","Tissue RNA - thymus [nTPM]":"14.2","Tissue RNA - thyroid gland [nTPM]":"10.5","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"29.4","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"46.2","Tissue RNA - white matter [nTPM]":"34.6","Cell RNA - A-431 [nTPM]":"135.5","Cell RNA - A549 [nTPM]":"51.5","Cell RNA - AF22 [nTPM]":"301.6","Cell RNA - AN3-CA [nTPM]":"87.2","Cell RNA - ASC diff [nTPM]":"91.7","Cell RNA - ASC TERT1 [nTPM]":"154.1","Cell RNA - BEWO [nTPM]":"30.5","Cell RNA - BJ [nTPM]":"34.9","Cell RNA - BJ hTERT+ [nTPM]":"106.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"84.7","Cell RNA - CACO-2 [nTPM]":"70.6","Cell RNA - CAPAN-2 [nTPM]":"192.3","Cell RNA - Daudi [nTPM]":"92.7","Cell RNA - EFO-21 [nTPM]":"49.2","Cell RNA - fHDF\/TERT166 [nTPM]":"43.2","Cell RNA - GAMG [nTPM]":"186.0","Cell RNA - HaCaT [nTPM]":"101.0","Cell RNA - HAP1 [nTPM]":"127.3","Cell RNA - HBEC3-KT [nTPM]":"192.4","Cell RNA - HBF TERT88 [nTPM]":"53.6","Cell RNA - HDLM-2 [nTPM]":"77.1","Cell RNA - HEK 293 [nTPM]":"268.3","Cell RNA - HEL [nTPM]":"265.2","Cell RNA - HeLa [nTPM]":"32.6","Cell RNA - Hep G2 [nTPM]":"181.1","Cell RNA - HHSteC [nTPM]":"134.6","Cell RNA - HL-60 [nTPM]":"31.5","Cell RNA - HMC-1 [nTPM]":"74.6","Cell RNA - HSkMC [nTPM]":"106.1","Cell RNA - hTCEpi [nTPM]":"201.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"138.8","Cell RNA - hTERT-HME1 [nTPM]":"113.3","Cell RNA - hTERT-RPE1 [nTPM]":"29.8","Cell RNA - HUVEC TERT2 [nTPM]":"51.5","Cell RNA - JURKAT [nTPM]":"64.2","Cell RNA - K-562 [nTPM]":"153.8","Cell RNA - Karpas-707 [nTPM]":"174.8","Cell RNA - LHCN-M2 [nTPM]":"38.1","Cell RNA - MCF7 [nTPM]":"223.7","Cell RNA - MOLT-4 [nTPM]":"109.6","Cell RNA - NB-4 [nTPM]":"39.3","Cell RNA - NTERA-2 [nTPM]":"125.2","Cell RNA - OE19 [nTPM]":"92.6","Cell RNA - PC-3 [nTPM]":"35.2","Cell RNA - REH [nTPM]":"47.5","Cell RNA - RH-30 [nTPM]":"55.4","Cell RNA - RPMI-8226 [nTPM]":"126.6","Cell RNA - RPTEC TERT1 [nTPM]":"329.3","Cell RNA - RT4 [nTPM]":"153.3","Cell RNA - SCLC-21H [nTPM]":"93.9","Cell RNA - SH-SY5Y [nTPM]":"47.6","Cell RNA - SiHa [nTPM]":"71.6","Cell RNA - SK-BR-3 [nTPM]":"226.3","Cell RNA - SK-MEL-30 [nTPM]":"74.1","Cell RNA - SuSa [nTPM]":"96.5","Cell RNA - T-47d [nTPM]":"60.7","Cell RNA - THP-1 [nTPM]":"81.3","Cell RNA - TIME [nTPM]":"50.8","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"66.0","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"31.6","Cell RNA - U-266\/70 [nTPM]":"31.6","Cell RNA - U-266\/84 [nTPM]":"69.6","Cell RNA - U-698 [nTPM]":"126.6","Cell RNA - U-87 MG [nTPM]":"32.0","Cell RNA - U-937 [nTPM]":"93.7","Cell RNA - WM-115 [nTPM]":"33.8","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"10.6","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"5.0","Blood RNA - memory B-cell [nTPM]":"16.6","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.5","Blood RNA - myeloid DC [nTPM]":"15.2","Blood RNA - naive B-cell [nTPM]":"17.1","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"12.6","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"7.1","Blood RNA - total PBMC [nTPM]":"7.7","Brain RNA - amygdala [nTPM]":"17.5","Brain RNA - basal ganglia [nTPM]":"27.0","Brain RNA - cerebellum [nTPM]":"26.8","Brain RNA - cerebral cortex [nTPM]":"24.0","Brain RNA - hippocampal formation [nTPM]":"18.6","Brain RNA - hypothalamus [nTPM]":"24.4","Brain RNA - medulla oblongata [nTPM]":"47.3","Brain RNA - midbrain [nTPM]":"27.7","Brain RNA - pons [nTPM]":"35.1","Brain RNA - spinal cord [nTPM]":"27.6","Brain RNA - thalamus [nTPM]":"21.8","Brain RNA - white matter [nTPM]":"34.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"97.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"34.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"64.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"199.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"41.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"129.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"99.7","Single Cell Type RNA - dendritic cells [nTPM]":"20.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"81.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.3","Single Cell Type RNA - Early spermatids [nTPM]":"21.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"95.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.3","Single Cell Type RNA - Endothelial cells [nTPM]":"39.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.7","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"83.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"133.7","Single Cell Type RNA - Fibroblasts [nTPM]":"35.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"51.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"80.5","Single Cell Type RNA - granulocytes [nTPM]":"41.3","Single Cell Type RNA - Granulosa cells [nTPM]":"77.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"127.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"61.1","Single Cell Type RNA - Horizontal cells [nTPM]":"148.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"58.0","Single Cell Type RNA - Ionocytes [nTPM]":"126.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.1","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"22.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"91.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.3","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"77.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"98.6","Single Cell Type RNA - Paneth cells [nTPM]":"38.4","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"30.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"123.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.0","Single Cell Type RNA - Spermatocytes [nTPM]":"179.5","Single Cell Type RNA - Spermatogonia [nTPM]":"128.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"69.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"89.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"217.1","Single Cell Type RNA - T-cells [nTPM]":"21.1","Single Cell Type RNA - Theca cells [nTPM]":"171.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.0","Single Cell Type RNA - Urothelial cells [nTPM]":"114.8"},{"Gene":"TM7SF2","Gene synonym":["ANG1","DHCR14A","NET47"],"Ensembl":"ENSG00000149809","Gene description":"Transmembrane 7 superfamily member 2","Uniprot":["O76062"],"Chromosome":"11","Position":"65111845-65116384","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"246.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"482.7","Hepatocytes":"220.6","Muller glia cells":"204.7","Theca cells":"204.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"38.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"69.2","RPTEC TERT1":"86.2","T-47d":"143.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030691","HPA072704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA030691":"AB_10602480","HPA072704":"AB_2686551"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"63.4","Tissue RNA - adrenal gland [nTPM]":"246.0","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"28.5","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"29.1","Tissue RNA - cerebellum [nTPM]":"32.8","Tissue RNA - cerebral cortex [nTPM]":"33.9","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"64.1","Tissue RNA - colon [nTPM]":"7.8","Tissue RNA - duodenum [nTPM]":"9.4","Tissue RNA - endometrium 1 [nTPM]":"3.4","Tissue RNA - epididymis [nTPM]":"17.0","Tissue RNA - esophagus [nTPM]":"39.6","Tissue RNA - fallopian tube [nTPM]":"12.8","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"47.3","Tissue RNA - hippocampal formation [nTPM]":"30.0","Tissue RNA - hypothalamus [nTPM]":"29.7","Tissue RNA - kidney [nTPM]":"18.9","Tissue RNA - liver [nTPM]":"86.4","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"34.0","Tissue RNA - midbrain [nTPM]":"32.0","Tissue RNA - ovary [nTPM]":"36.5","Tissue RNA - pancreas [nTPM]":"69.9","Tissue RNA - parathyroid gland [nTPM]":"36.3","Tissue RNA - pituitary gland [nTPM]":"19.5","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"32.5","Tissue RNA - prostate [nTPM]":"41.1","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"46.9","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"68.2","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"30.1","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"35.6","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"32.6","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"22.1","Tissue RNA - white matter [nTPM]":"35.1","Cell RNA - A-431 [nTPM]":"7.7","Cell RNA - A549 [nTPM]":"10.9","Cell RNA - AF22 [nTPM]":"27.3","Cell RNA - AN3-CA [nTPM]":"35.1","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"15.4","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"26.0","Cell RNA - CAPAN-2 [nTPM]":"35.8","Cell RNA - Daudi [nTPM]":"16.3","Cell RNA - EFO-21 [nTPM]":"26.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.2","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"13.3","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"21.2","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"16.7","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"54.5","Cell RNA - HHSteC [nTPM]":"18.8","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"3.7","Cell RNA - hTCEpi [nTPM]":"5.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.6","Cell RNA - hTERT-HME1 [nTPM]":"3.9","Cell RNA - hTERT-RPE1 [nTPM]":"12.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"13.9","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"69.2","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"18.6","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"18.4","Cell RNA - PC-3 [nTPM]":"11.2","Cell RNA - REH [nTPM]":"22.4","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"39.9","Cell RNA - RPTEC TERT1 [nTPM]":"86.2","Cell RNA - RT4 [nTPM]":"12.6","Cell RNA - SCLC-21H [nTPM]":"27.2","Cell RNA - SH-SY5Y [nTPM]":"30.5","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"28.2","Cell RNA - SK-MEL-30 [nTPM]":"6.1","Cell RNA - SuSa [nTPM]":"19.5","Cell RNA - T-47d [nTPM]":"143.9","Cell RNA - THP-1 [nTPM]":"11.4","Cell RNA - TIME [nTPM]":"3.1","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.3","Cell RNA - U-266\/70 [nTPM]":"27.1","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"8.4","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"12.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"11.8","Blood RNA - naive CD8 T-cell [nTPM]":"9.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"12.5","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"38.1","Blood RNA - T-reg [nTPM]":"5.6","Blood RNA - total PBMC [nTPM]":"4.9","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"28.5","Brain RNA - cerebellum [nTPM]":"32.8","Brain RNA - cerebral cortex [nTPM]":"33.9","Brain RNA - hippocampal formation [nTPM]":"30.0","Brain RNA - hypothalamus [nTPM]":"29.7","Brain RNA - medulla oblongata [nTPM]":"34.0","Brain RNA - midbrain [nTPM]":"32.0","Brain RNA - pons [nTPM]":"32.5","Brain RNA - spinal cord [nTPM]":"30.1","Brain RNA - thalamus [nTPM]":"32.6","Brain RNA - white matter [nTPM]":"35.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"12.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"99.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"36.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.9","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"59.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"482.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"220.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.8","Single Cell Type RNA - Ionocytes [nTPM]":"52.9","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.7","Single Cell Type RNA - Late spermatids [nTPM]":"59.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.4","Single Cell Type RNA - Muller glia cells [nTPM]":"204.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.7","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"77.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.8","Single Cell Type RNA - Spermatocytes [nTPM]":"13.3","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.1","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"204.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.0","Single Cell Type RNA - Urothelial cells [nTPM]":"10.4"}]