[{"Gene":"ALDH1L1","Gene synonym":["10-fTHF","FDH","FTHFD"],"Ensembl":"ENSG00000144908","Gene description":"Aldehyde dehydrogenase 1 family member L1","Uniprot":["O75891"],"Chromosome":"3","Position":"126103562-126197994","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"369.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"633.3","Proximal tubular cells":"197.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"40.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"36.5","Hep G2":"78.1","Karpas-707":"82.0","RPMI-8226":"45.0","RT4":"219.1","U-266\/70":"44.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036900","HPA050139"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036900":"AB_10672273","HPA050139":"AB_2681031"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.42e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.4","Tissue RNA - adrenal gland [nTPM]":"37.2","Tissue RNA - amygdala [nTPM]":"53.4","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"28.8","Tissue RNA - cerebellum [nTPM]":"55.9","Tissue RNA - cerebral cortex [nTPM]":"63.6","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"37.7","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"26.5","Tissue RNA - hippocampal formation [nTPM]":"47.5","Tissue RNA - hypothalamus [nTPM]":"56.2","Tissue RNA - kidney [nTPM]":"116.6","Tissue RNA - liver [nTPM]":"369.7","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"56.7","Tissue RNA - midbrain [nTPM]":"52.9","Tissue RNA - ovary [nTPM]":"45.3","Tissue RNA - pancreas [nTPM]":"44.3","Tissue RNA - parathyroid gland [nTPM]":"15.1","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"53.0","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"88.6","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"90.7","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"48.4","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"53.9","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"59.9","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"28.3","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"46.0","Cell RNA - A-431 [nTPM]":"1.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"36.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"2.6","Cell RNA - EFO-21 [nTPM]":"10.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"78.1","Cell RNA - HHSteC [nTPM]":"10.6","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"82.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"45.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"219.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"10.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"1.4","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"44.8","Cell RNA - U-266\/84 [nTPM]":"14.8","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"53.4","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"55.9","Brain RNA - cerebral cortex [nTPM]":"63.6","Brain RNA - hippocampal formation [nTPM]":"47.5","Brain RNA - hypothalamus [nTPM]":"56.2","Brain RNA - medulla oblongata [nTPM]":"56.7","Brain RNA - midbrain [nTPM]":"52.9","Brain RNA - pons [nTPM]":"53.0","Brain RNA - spinal cord [nTPM]":"48.4","Brain RNA - thalamus [nTPM]":"53.9","Brain RNA - white matter [nTPM]":"46.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"92.7","Single Cell Type RNA - B-cells [nTPM]":"4.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"53.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"44.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"22.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"34.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"633.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"35.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"9.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"40.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"197.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"61.7"},{"Gene":"ALDH1L2","Gene synonym":["FLJ38508","mtFDH"],"Ensembl":"ENSG00000136010","Gene description":"Aldehyde dehydrogenase 1 family member L2","Uniprot":["Q3SY69"],"Chromosome":"12","Position":"105019784-105107643","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"40.7","salivary gland":"13.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"23.1","Inhibitory neurons":"24.0","Oligodendrocyte precursor cells":"25.1","Plasma cells":"14.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"62.8","ASC TERT1":"85.2","fHDF\/TERT166":"102.4","HHSteC":"55.6","HSkMC":"69.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039481","HPA059282"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039481":"AB_10795465","HPA059282":"AB_2732633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-5"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"40.7","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"3.3","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"27.3","Cell RNA - ASC diff [nTPM]":"62.8","Cell RNA - ASC TERT1 [nTPM]":"85.2","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"40.8","Cell RNA - BJ hTERT+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.5","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"102.4","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"55.6","Cell RNA - HL-60 [nTPM]":"5.3","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"69.7","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"25.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"37.7","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"20.5","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"6.0","Cell RNA - THP-1 [nTPM]":"44.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"3.9","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"45.5","Cell RNA - U-266\/84 [nTPM]":"12.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"16.2","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"AMT","Gene synonym":["GCST","NKH"],"Ensembl":"ENSG00000145020","Gene description":"Aminomethyltransferase","Uniprot":["P48728"],"Chromosome":"3","Position":"49416778-49422685","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"49.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"42.4","Proximal enterocytes":"33.3","Undifferentiated cells":"31.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"7.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"17.1","Hep G2":"47.5","NTERA-2":"8.0","SH-SY5Y":"14.9","SuSa":"9.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005566"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005566":"AB_1844811"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"13.1","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"13.8","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"49.1","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"12.5","Tissue RNA - pancreas [nTPM]":"19.5","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"11.9","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"11.8","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"8.0","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"47.5","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.1","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.6","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.7","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"2.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"42.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"26.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.3","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.6","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"DHFR","Gene synonym":[],"Ensembl":"ENSG00000228716","Gene description":"Dihydrofolate reductase","Uniprot":["P00374"],"Chromosome":"5","Position":"80626226-80654983","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Methotrexate resistance","One-carbon metabolism"],"Molecular function":["Oxidoreductase","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"145.8","Spermatocytes":"132.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037129","HPA051465"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB037129":"AB_439683","HPA051465":"AB_2681494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.2","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"15.3","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"16.5","Tissue RNA - bone marrow [nTPM]":"54.3","Tissue RNA - breast [nTPM]":"12.0","Tissue RNA - cerebellum [nTPM]":"15.8","Tissue RNA - cerebral cortex [nTPM]":"21.9","Tissue RNA - cervix [nTPM]":"8.0","Tissue RNA - choroid plexus [nTPM]":"13.3","Tissue RNA - colon [nTPM]":"21.4","Tissue RNA - duodenum [nTPM]":"24.5","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"14.1","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"15.5","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"60.1","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"41.5","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"9.1","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"14.4","Tissue RNA - pons [nTPM]":"16.6","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"25.3","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"19.6","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"25.1","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"60.7","Tissue RNA - thyroid gland [nTPM]":"8.2","Tissue RNA - tongue [nTPM]":"25.8","Tissue RNA - tonsil [nTPM]":"39.5","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"5.7","Tissue RNA - white matter [nTPM]":"17.7","Cell RNA - A-431 [nTPM]":"98.1","Cell RNA - A549 [nTPM]":"66.6","Cell RNA - AF22 [nTPM]":"164.8","Cell RNA - AN3-CA [nTPM]":"122.7","Cell RNA - ASC diff [nTPM]":"30.7","Cell RNA - ASC TERT1 [nTPM]":"32.0","Cell RNA - BEWO [nTPM]":"60.6","Cell RNA - BJ [nTPM]":"76.5","Cell RNA - BJ hTERT+ [nTPM]":"58.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"130.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"149.0","Cell RNA - CACO-2 [nTPM]":"63.8","Cell RNA - CAPAN-2 [nTPM]":"114.6","Cell RNA - Daudi [nTPM]":"196.9","Cell RNA - EFO-21 [nTPM]":"32.5","Cell RNA - fHDF\/TERT166 [nTPM]":"44.6","Cell RNA - GAMG [nTPM]":"106.0","Cell RNA - HaCaT [nTPM]":"67.0","Cell RNA - HAP1 [nTPM]":"214.4","Cell RNA - HBEC3-KT [nTPM]":"98.6","Cell RNA - HBF TERT88 [nTPM]":"208.5","Cell RNA - HDLM-2 [nTPM]":"88.2","Cell RNA - HEK 293 [nTPM]":"132.1","Cell RNA - HEL [nTPM]":"94.8","Cell RNA - HeLa [nTPM]":"104.5","Cell RNA - Hep G2 [nTPM]":"59.5","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"111.7","Cell RNA - HMC-1 [nTPM]":"40.3","Cell RNA - HSkMC [nTPM]":"22.3","Cell RNA - hTCEpi [nTPM]":"9.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.9","Cell RNA - hTERT-HME1 [nTPM]":"13.0","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"63.9","Cell RNA - JURKAT [nTPM]":"142.0","Cell RNA - K-562 [nTPM]":"108.3","Cell RNA - Karpas-707 [nTPM]":"146.7","Cell RNA - LHCN-M2 [nTPM]":"133.5","Cell RNA - MCF7 [nTPM]":"98.2","Cell RNA - MOLT-4 [nTPM]":"276.5","Cell RNA - NB-4 [nTPM]":"44.9","Cell RNA - NTERA-2 [nTPM]":"83.6","Cell RNA - OE19 [nTPM]":"48.3","Cell RNA - PC-3 [nTPM]":"38.5","Cell RNA - REH [nTPM]":"176.7","Cell RNA - RH-30 [nTPM]":"323.3","Cell RNA - RPMI-8226 [nTPM]":"194.1","Cell RNA - RPTEC TERT1 [nTPM]":"75.1","Cell RNA - RT4 [nTPM]":"61.5","Cell RNA - SCLC-21H [nTPM]":"134.3","Cell RNA - SH-SY5Y [nTPM]":"93.7","Cell RNA - SiHa [nTPM]":"107.9","Cell RNA - SK-BR-3 [nTPM]":"49.9","Cell RNA - SK-MEL-30 [nTPM]":"54.6","Cell RNA - SuSa [nTPM]":"83.5","Cell RNA - T-47d [nTPM]":"98.5","Cell RNA - THP-1 [nTPM]":"108.6","Cell RNA - TIME [nTPM]":"38.5","Cell RNA - U-138 MG [nTPM]":"41.0","Cell RNA - U-2 OS [nTPM]":"62.0","Cell RNA - U-2197 [nTPM]":"116.0","Cell RNA - U-251 MG [nTPM]":"148.3","Cell RNA - U-266\/70 [nTPM]":"68.2","Cell RNA - U-266\/84 [nTPM]":"146.6","Cell RNA - U-698 [nTPM]":"210.3","Cell RNA - U-87 MG [nTPM]":"91.5","Cell RNA - U-937 [nTPM]":"222.1","Cell RNA - WM-115 [nTPM]":"107.7","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"15.3","Brain RNA - basal ganglia [nTPM]":"16.5","Brain RNA - cerebellum [nTPM]":"15.8","Brain RNA - cerebral cortex [nTPM]":"21.9","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"15.5","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"16.6","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"17.7","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"21.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - dendritic cells [nTPM]":"7.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"7.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.7","Single Cell Type RNA - Endothelial cells [nTPM]":"7.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"145.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"48.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"7.1","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"60.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"132.2","Single Cell Type RNA - Spermatogonia [nTPM]":"49.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.3","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.1"},{"Gene":"DHFR2","Gene synonym":["DHFRL1","DHFRP4","FLJ16119"],"Ensembl":"ENSG00000178700","Gene description":"Dihydrofolate reductase 2","Uniprot":["Q86XF0"],"Chromosome":"3","Position":"94047836-94063389","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"12.8","Ductal cells":"6.3","Respiratory ciliated cells":"8.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"hTERT-RPE1":"154.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051465"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051465":"AB_2681494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"6.0","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"6.4","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"5.9","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"4.5","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"4.2","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"2.1","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"3.8","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"4.4","Cell RNA - ASC diff [nTPM]":"5.7","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.2","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"5.7","Cell RNA - Daudi [nTPM]":"2.5","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"3.7","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"3.3","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"4.4","Cell RNA - HDLM-2 [nTPM]":"8.5","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"3.6","Cell RNA - HSkMC [nTPM]":"7.6","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"154.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"11.9","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"5.6","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"4.5","Cell RNA - MOLT-4 [nTPM]":"10.8","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"3.7","Cell RNA - OE19 [nTPM]":"10.8","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"5.7","Cell RNA - RPMI-8226 [nTPM]":"4.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"5.3","Cell RNA - SiHa [nTPM]":"8.3","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"9.6","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"4.8","Cell RNA - U-138 MG [nTPM]":"4.4","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"4.1","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"4.4","Cell RNA - U-937 [nTPM]":"5.5","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"6.0","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"3.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"DLD","Gene synonym":["DLDH","E3","GCSL","LAD","OGDC-E3"],"Ensembl":"ENSG00000091140","Gene description":"Dihydrolipoamide dehydrogenase","Uniprot":["P09622"],"Chromosome":"7","Position":"107891162-107931730","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"357.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"356.2","Distal tubular cells":"226.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044849"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044849":"AB_2679111"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.58e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Tissue RNA - adipose tissue [nTPM]":"108.7","Tissue RNA - adrenal gland [nTPM]":"98.9","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"42.1","Tissue RNA - basal ganglia [nTPM]":"23.7","Tissue RNA - bone marrow [nTPM]":"54.0","Tissue RNA - breast [nTPM]":"49.0","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"29.1","Tissue RNA - cervix [nTPM]":"36.3","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"109.0","Tissue RNA - duodenum [nTPM]":"81.8","Tissue RNA - endometrium 1 [nTPM]":"45.3","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"94.1","Tissue RNA - fallopian tube [nTPM]":"34.3","Tissue RNA - gallbladder [nTPM]":"48.5","Tissue RNA - heart muscle [nTPM]":"264.1","Tissue RNA - hippocampal formation [nTPM]":"23.1","Tissue RNA - hypothalamus [nTPM]":"29.5","Tissue RNA - kidney [nTPM]":"153.3","Tissue RNA - liver [nTPM]":"112.8","Tissue RNA - lung [nTPM]":"39.3","Tissue RNA - lymph node [nTPM]":"50.1","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"27.4","Tissue RNA - ovary [nTPM]":"30.0","Tissue RNA - pancreas [nTPM]":"49.2","Tissue RNA - parathyroid gland [nTPM]":"136.7","Tissue RNA - pituitary gland [nTPM]":"27.8","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"26.6","Tissue RNA - prostate [nTPM]":"45.7","Tissue RNA - rectum [nTPM]":"99.3","Tissue RNA - retina [nTPM]":"35.0","Tissue RNA - salivary gland [nTPM]":"50.2","Tissue RNA - seminal vesicle [nTPM]":"50.3","Tissue RNA - skeletal muscle [nTPM]":"295.0","Tissue RNA - skin 1 [nTPM]":"38.9","Tissue RNA - small intestine [nTPM]":"71.9","Tissue RNA - smooth muscle [nTPM]":"67.7","Tissue RNA - spinal cord [nTPM]":"24.9","Tissue RNA - spleen [nTPM]":"38.4","Tissue RNA - stomach 1 [nTPM]":"80.5","Tissue RNA - testis [nTPM]":"31.3","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"43.2","Tissue RNA - thyroid gland [nTPM]":"64.2","Tissue RNA - tongue [nTPM]":"357.0","Tissue RNA - tonsil [nTPM]":"67.5","Tissue RNA - urinary bladder [nTPM]":"66.1","Tissue RNA - vagina [nTPM]":"32.7","Tissue RNA - white matter [nTPM]":"23.4","Cell RNA - A-431 [nTPM]":"171.4","Cell RNA - A549 [nTPM]":"134.5","Cell RNA - AF22 [nTPM]":"74.8","Cell RNA - AN3-CA [nTPM]":"127.9","Cell RNA - ASC diff [nTPM]":"104.6","Cell RNA - ASC TERT1 [nTPM]":"91.4","Cell RNA - BEWO [nTPM]":"88.4","Cell RNA - BJ [nTPM]":"96.5","Cell RNA - BJ hTERT+ [nTPM]":"80.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"110.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.2","Cell RNA - CACO-2 [nTPM]":"159.5","Cell RNA - CAPAN-2 [nTPM]":"95.5","Cell RNA - Daudi [nTPM]":"165.9","Cell RNA - EFO-21 [nTPM]":"159.6","Cell RNA - fHDF\/TERT166 [nTPM]":"103.0","Cell RNA - GAMG [nTPM]":"177.7","Cell RNA - HaCaT [nTPM]":"110.9","Cell RNA - HAP1 [nTPM]":"150.2","Cell RNA - HBEC3-KT [nTPM]":"135.8","Cell RNA - HBF TERT88 [nTPM]":"166.1","Cell RNA - HDLM-2 [nTPM]":"111.1","Cell RNA - HEK 293 [nTPM]":"88.4","Cell RNA - HEL [nTPM]":"116.9","Cell RNA - HeLa [nTPM]":"175.6","Cell RNA - Hep G2 [nTPM]":"116.7","Cell RNA - HHSteC [nTPM]":"80.3","Cell RNA - HL-60 [nTPM]":"194.7","Cell RNA - HMC-1 [nTPM]":"116.0","Cell RNA - HSkMC [nTPM]":"104.8","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.4","Cell RNA - hTERT-HME1 [nTPM]":"63.4","Cell RNA - hTERT-RPE1 [nTPM]":"72.3","Cell RNA - HUVEC TERT2 [nTPM]":"134.0","Cell RNA - JURKAT [nTPM]":"137.0","Cell RNA - K-562 [nTPM]":"298.5","Cell RNA - Karpas-707 [nTPM]":"119.7","Cell RNA - LHCN-M2 [nTPM]":"121.8","Cell RNA - MCF7 [nTPM]":"188.1","Cell RNA - MOLT-4 [nTPM]":"161.8","Cell RNA - NB-4 [nTPM]":"138.9","Cell RNA - NTERA-2 [nTPM]":"87.4","Cell RNA - OE19 [nTPM]":"206.0","Cell RNA - PC-3 [nTPM]":"98.2","Cell RNA - REH [nTPM]":"113.1","Cell RNA - RH-30 [nTPM]":"117.8","Cell RNA - RPMI-8226 [nTPM]":"225.9","Cell RNA - RPTEC TERT1 [nTPM]":"151.8","Cell RNA - RT4 [nTPM]":"250.8","Cell RNA - SCLC-21H [nTPM]":"92.3","Cell RNA - SH-SY5Y [nTPM]":"99.9","Cell RNA - SiHa [nTPM]":"156.3","Cell RNA - SK-BR-3 [nTPM]":"262.1","Cell RNA - SK-MEL-30 [nTPM]":"143.9","Cell RNA - SuSa [nTPM]":"149.9","Cell RNA - T-47d [nTPM]":"100.5","Cell RNA - THP-1 [nTPM]":"165.8","Cell RNA - TIME [nTPM]":"87.9","Cell RNA - U-138 MG [nTPM]":"120.7","Cell RNA - U-2 OS [nTPM]":"97.3","Cell RNA - U-2197 [nTPM]":"238.1","Cell RNA - U-251 MG [nTPM]":"149.4","Cell RNA - U-266\/70 [nTPM]":"89.3","Cell RNA - U-266\/84 [nTPM]":"187.1","Cell RNA - U-698 [nTPM]":"114.6","Cell RNA - U-87 MG [nTPM]":"115.0","Cell RNA - U-937 [nTPM]":"204.1","Cell RNA - WM-115 [nTPM]":"130.2","Blood RNA - basophil [nTPM]":"132.7","Blood RNA - classical monocyte [nTPM]":"63.9","Blood RNA - eosinophil [nTPM]":"136.0","Blood RNA - gdT-cell [nTPM]":"46.9","Blood RNA - intermediate monocyte [nTPM]":"81.6","Blood RNA - MAIT T-cell [nTPM]":"49.4","Blood RNA - memory B-cell [nTPM]":"37.8","Blood RNA - memory CD4 T-cell [nTPM]":"46.8","Blood RNA - memory CD8 T-cell [nTPM]":"46.8","Blood RNA - myeloid DC [nTPM]":"87.2","Blood RNA - naive B-cell [nTPM]":"38.5","Blood RNA - naive CD4 T-cell [nTPM]":"47.9","Blood RNA - naive CD8 T-cell [nTPM]":"50.5","Blood RNA - neutrophil [nTPM]":"39.9","Blood RNA - NK-cell [nTPM]":"68.1","Blood RNA - non-classical monocyte [nTPM]":"116.9","Blood RNA - plasmacytoid DC [nTPM]":"29.9","Blood RNA - T-reg [nTPM]":"49.0","Blood RNA - total PBMC [nTPM]":"64.2","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"23.7","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"29.1","Brain RNA - hippocampal formation [nTPM]":"23.1","Brain RNA - hypothalamus [nTPM]":"29.5","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"27.4","Brain RNA - pons [nTPM]":"26.6","Brain RNA - spinal cord [nTPM]":"24.9","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"23.4","Single Cell Type RNA - Adipocytes [nTPM]":"26.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"26.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"42.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"124.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"47.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"356.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"70.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.2","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"226.9","Single Cell Type RNA - Ductal cells [nTPM]":"69.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.2","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.6","Single Cell Type RNA - Erythroid cells [nTPM]":"53.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.0","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"35.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"86.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.1","Single Cell Type RNA - Ionocytes [nTPM]":"114.0","Single Cell Type RNA - Kupffer cells [nTPM]":"41.0","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"23.3","Single Cell Type RNA - Macrophages [nTPM]":"37.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"62.2","Single Cell Type RNA - Muller glia cells [nTPM]":"36.0","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.4","Single Cell Type RNA - Peritubular cells [nTPM]":"42.2","Single Cell Type RNA - Plasma cells [nTPM]":"30.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"178.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.8","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"108.4","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"73.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.7","Single Cell Type RNA - Urothelial cells [nTPM]":"39.2"},{"Gene":"FPGS","Gene synonym":[],"Ensembl":"ENSG00000136877","Gene description":"Folylpolyglutamate synthase","Uniprot":["Q05932"],"Chromosome":"9","Position":"127794597-127814327","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050488"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050488":"AB_2681143"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.08e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"37.3","Tissue RNA - adrenal gland [nTPM]":"49.1","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"15.5","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"19.7","Tissue RNA - breast [nTPM]":"32.6","Tissue RNA - cerebellum [nTPM]":"9.1","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"26.6","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"19.5","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"29.6","Tissue RNA - epididymis [nTPM]":"8.4","Tissue RNA - esophagus [nTPM]":"22.1","Tissue RNA - fallopian tube [nTPM]":"35.5","Tissue RNA - gallbladder [nTPM]":"9.1","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"66.1","Tissue RNA - lung [nTPM]":"30.6","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"9.6","Tissue RNA - ovary [nTPM]":"55.4","Tissue RNA - pancreas [nTPM]":"28.0","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"26.6","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"20.4","Tissue RNA - seminal vesicle [nTPM]":"11.6","Tissue RNA - skeletal muscle [nTPM]":"48.2","Tissue RNA - skin 1 [nTPM]":"15.5","Tissue RNA - small intestine [nTPM]":"22.8","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"29.9","Tissue RNA - stomach 1 [nTPM]":"25.8","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"13.4","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"19.0","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"25.6","Tissue RNA - vagina [nTPM]":"18.2","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"36.2","Cell RNA - A549 [nTPM]":"24.4","Cell RNA - AF22 [nTPM]":"14.2","Cell RNA - AN3-CA [nTPM]":"29.7","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"42.6","Cell RNA - BJ [nTPM]":"28.0","Cell RNA - BJ hTERT+ [nTPM]":"33.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.0","Cell RNA - CACO-2 [nTPM]":"26.4","Cell RNA - CAPAN-2 [nTPM]":"56.7","Cell RNA - Daudi [nTPM]":"44.4","Cell RNA - EFO-21 [nTPM]":"35.8","Cell RNA - fHDF\/TERT166 [nTPM]":"38.9","Cell RNA - GAMG [nTPM]":"24.4","Cell RNA - HaCaT [nTPM]":"67.0","Cell RNA - HAP1 [nTPM]":"17.7","Cell RNA - HBEC3-KT [nTPM]":"39.4","Cell RNA - HBF TERT88 [nTPM]":"11.4","Cell RNA - HDLM-2 [nTPM]":"48.5","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"34.5","Cell RNA - HeLa [nTPM]":"30.4","Cell RNA - Hep G2 [nTPM]":"32.1","Cell RNA - HHSteC [nTPM]":"50.5","Cell RNA - HL-60 [nTPM]":"64.2","Cell RNA - HMC-1 [nTPM]":"28.1","Cell RNA - HSkMC [nTPM]":"32.2","Cell RNA - hTCEpi [nTPM]":"21.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.7","Cell RNA - hTERT-HME1 [nTPM]":"43.8","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"43.3","Cell RNA - JURKAT [nTPM]":"41.6","Cell RNA - K-562 [nTPM]":"39.8","Cell RNA - Karpas-707 [nTPM]":"27.7","Cell RNA - LHCN-M2 [nTPM]":"36.2","Cell RNA - MCF7 [nTPM]":"45.8","Cell RNA - MOLT-4 [nTPM]":"56.6","Cell RNA - NB-4 [nTPM]":"47.8","Cell RNA - NTERA-2 [nTPM]":"39.9","Cell RNA - OE19 [nTPM]":"39.2","Cell RNA - PC-3 [nTPM]":"74.0","Cell RNA - REH [nTPM]":"116.0","Cell RNA - RH-30 [nTPM]":"23.0","Cell RNA - RPMI-8226 [nTPM]":"77.7","Cell RNA - RPTEC TERT1 [nTPM]":"52.2","Cell RNA - RT4 [nTPM]":"29.3","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"35.0","Cell RNA - SiHa [nTPM]":"80.1","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"5.8","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"23.7","Cell RNA - THP-1 [nTPM]":"26.8","Cell RNA - TIME [nTPM]":"65.4","Cell RNA - U-138 MG [nTPM]":"18.6","Cell RNA - U-2 OS [nTPM]":"26.0","Cell RNA - U-2197 [nTPM]":"54.1","Cell RNA - U-251 MG [nTPM]":"56.8","Cell RNA - U-266\/70 [nTPM]":"31.0","Cell RNA - U-266\/84 [nTPM]":"14.2","Cell RNA - U-698 [nTPM]":"36.0","Cell RNA - U-87 MG [nTPM]":"40.7","Cell RNA - U-937 [nTPM]":"29.4","Cell RNA - WM-115 [nTPM]":"26.7","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"38.8","Blood RNA - intermediate monocyte [nTPM]":"23.9","Blood RNA - MAIT T-cell [nTPM]":"35.1","Blood RNA - memory B-cell [nTPM]":"23.2","Blood RNA - memory CD4 T-cell [nTPM]":"22.9","Blood RNA - memory CD8 T-cell [nTPM]":"34.0","Blood RNA - myeloid DC [nTPM]":"30.8","Blood RNA - naive B-cell [nTPM]":"27.6","Blood RNA - naive CD4 T-cell [nTPM]":"18.5","Blood RNA - naive CD8 T-cell [nTPM]":"25.2","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"43.6","Blood RNA - non-classical monocyte [nTPM]":"23.9","Blood RNA - plasmacytoid DC [nTPM]":"38.9","Blood RNA - T-reg [nTPM]":"26.6","Blood RNA - total PBMC [nTPM]":"22.4","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"9.1","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"9.6","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"28.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"21.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - dendritic cells [nTPM]":"21.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"49.6","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.9","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.9","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"73.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"18.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"46.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.9","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"32.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.8","Single Cell Type RNA - T-cells [nTPM]":"22.2","Single Cell Type RNA - Theca cells [nTPM]":"14.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.5"},{"Gene":"FTCD","Gene synonym":[],"Ensembl":"ENSG00000160282","Gene description":"Formimidoyltransferase cyclodeaminase","Uniprot":["O95954"],"Chromosome":"21","Position":"46136262-46155579","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Histidine metabolism"],"Molecular function":["Lyase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"939.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"131.5","Early spermatids":"104.7","Hepatocytes":"444.9","Late spermatids":"124.3","Proximal tubular cells":"395.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"87.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Hep G2":"92.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020073","HPA030928","HPA030929","HPA036114"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA020073":"AB_1849005","HPA030928":"AB_2673664","HPA030929":"AB_2673665","HPA036114":"AB_2674947"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"155.7","Tissue RNA - liver [nTPM]":"939.8","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"92.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"8.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"104.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"61.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"444.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"124.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"395.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"39.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GCSH","Gene synonym":[],"Ensembl":"ENSG00000140905","Gene description":"Glycine cleavage system protein H","Uniprot":["P23434"],"Chromosome":"16","Position":"81081945-81096395","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"553.4","Extravillous trophoblasts":"1476.4","Proximal tubular cells":"655.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041368","HPA057079"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041368":"AB_10804001","HPA057079":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.7","Tissue RNA - adrenal gland [nTPM]":"20.1","Tissue RNA - amygdala [nTPM]":"58.9","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"66.5","Tissue RNA - bone marrow [nTPM]":"6.3","Tissue RNA - breast [nTPM]":"24.2","Tissue RNA - cerebellum [nTPM]":"62.9","Tissue RNA - cerebral cortex [nTPM]":"113.8","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"50.8","Tissue RNA - colon [nTPM]":"16.0","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"17.5","Tissue RNA - epididymis [nTPM]":"68.9","Tissue RNA - esophagus [nTPM]":"15.5","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"38.1","Tissue RNA - hippocampal formation [nTPM]":"55.8","Tissue RNA - hypothalamus [nTPM]":"60.9","Tissue RNA - kidney [nTPM]":"78.2","Tissue RNA - liver [nTPM]":"118.9","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"6.7","Tissue RNA - medulla oblongata [nTPM]":"60.1","Tissue RNA - midbrain [nTPM]":"66.0","Tissue RNA - ovary [nTPM]":"18.4","Tissue RNA - pancreas [nTPM]":"19.7","Tissue RNA - parathyroid gland [nTPM]":"31.0","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"26.0","Tissue RNA - pons [nTPM]":"61.1","Tissue RNA - prostate [nTPM]":"18.7","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"59.3","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"61.7","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"17.5","Tissue RNA - testis [nTPM]":"7.4","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"10.4","Tissue RNA - thyroid gland [nTPM]":"96.4","Tissue RNA - tongue [nTPM]":"63.6","Tissue RNA - tonsil [nTPM]":"9.3","Tissue RNA - urinary bladder [nTPM]":"18.3","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"67.8","Cell RNA - A-431 [nTPM]":"63.6","Cell RNA - A549 [nTPM]":"28.3","Cell RNA - AF22 [nTPM]":"82.4","Cell RNA - AN3-CA [nTPM]":"37.0","Cell RNA - ASC diff [nTPM]":"40.4","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"175.5","Cell RNA - BJ [nTPM]":"35.9","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.6","Cell RNA - CACO-2 [nTPM]":"37.0","Cell RNA - CAPAN-2 [nTPM]":"57.2","Cell RNA - Daudi [nTPM]":"17.2","Cell RNA - EFO-21 [nTPM]":"32.3","Cell RNA - fHDF\/TERT166 [nTPM]":"15.9","Cell RNA - GAMG [nTPM]":"31.9","Cell RNA - HaCaT [nTPM]":"33.3","Cell RNA - HAP1 [nTPM]":"64.5","Cell RNA - HBEC3-KT [nTPM]":"36.5","Cell RNA - HBF TERT88 [nTPM]":"71.6","Cell RNA - HDLM-2 [nTPM]":"4.7","Cell RNA - HEK 293 [nTPM]":"86.7","Cell RNA - HEL [nTPM]":"21.8","Cell RNA - HeLa [nTPM]":"34.9","Cell RNA - Hep G2 [nTPM]":"114.6","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"70.3","Cell RNA - HMC-1 [nTPM]":"24.1","Cell RNA - HSkMC [nTPM]":"32.0","Cell RNA - hTCEpi [nTPM]":"47.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.8","Cell RNA - hTERT-HME1 [nTPM]":"53.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.0","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"45.1","Cell RNA - K-562 [nTPM]":"86.3","Cell RNA - Karpas-707 [nTPM]":"3.4","Cell RNA - LHCN-M2 [nTPM]":"42.9","Cell RNA - MCF7 [nTPM]":"67.7","Cell RNA - MOLT-4 [nTPM]":"45.9","Cell RNA - NB-4 [nTPM]":"138.8","Cell RNA - NTERA-2 [nTPM]":"113.0","Cell RNA - OE19 [nTPM]":"49.6","Cell RNA - PC-3 [nTPM]":"57.5","Cell RNA - REH [nTPM]":"72.7","Cell RNA - RH-30 [nTPM]":"44.1","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"98.4","Cell RNA - RT4 [nTPM]":"56.4","Cell RNA - SCLC-21H [nTPM]":"43.7","Cell RNA - SH-SY5Y [nTPM]":"45.3","Cell RNA - SiHa [nTPM]":"53.3","Cell RNA - SK-BR-3 [nTPM]":"32.9","Cell RNA - SK-MEL-30 [nTPM]":"70.8","Cell RNA - SuSa [nTPM]":"63.9","Cell RNA - T-47d [nTPM]":"48.3","Cell RNA - THP-1 [nTPM]":"33.2","Cell RNA - TIME [nTPM]":"19.8","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"37.8","Cell RNA - U-266\/70 [nTPM]":"14.7","Cell RNA - U-266\/84 [nTPM]":"31.8","Cell RNA - U-698 [nTPM]":"102.1","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"41.3","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"5.9","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"7.0","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"10.8","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"58.9","Brain RNA - basal ganglia [nTPM]":"66.5","Brain RNA - cerebellum [nTPM]":"62.9","Brain RNA - cerebral cortex [nTPM]":"113.8","Brain RNA - hippocampal formation [nTPM]":"55.8","Brain RNA - hypothalamus [nTPM]":"60.9","Brain RNA - medulla oblongata [nTPM]":"60.1","Brain RNA - midbrain [nTPM]":"66.0","Brain RNA - pons [nTPM]":"61.1","Brain RNA - spinal cord [nTPM]":"61.7","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"67.8","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.9","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"24.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"94.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"43.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"97.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"115.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"31.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"80.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"553.4","Single Cell Type RNA - dendritic cells [nTPM]":"13.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"295.4","Single Cell Type RNA - Ductal cells [nTPM]":"70.0","Single Cell Type RNA - Early spermatids [nTPM]":"32.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"128.3","Single Cell Type RNA - Endothelial cells [nTPM]":"31.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.4","Single Cell Type RNA - Erythroid cells [nTPM]":"71.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1476.4","Single Cell Type RNA - Fibroblasts [nTPM]":"61.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.2","Single Cell Type RNA - granulocytes [nTPM]":"36.3","Single Cell Type RNA - Granulosa cells [nTPM]":"38.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"352.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"118.8","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.3","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"34.6","Single Cell Type RNA - Late spermatids [nTPM]":"19.5","Single Cell Type RNA - Leydig cells [nTPM]":"140.8","Single Cell Type RNA - Macrophages [nTPM]":"18.8","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"17.7","Single Cell Type RNA - Muller glia cells [nTPM]":"215.8","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"42.3","Single Cell Type RNA - Paneth cells [nTPM]":"17.8","Single Cell Type RNA - Peritubular cells [nTPM]":"141.1","Single Cell Type RNA - Plasma cells [nTPM]":"51.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"123.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"655.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.2","Single Cell Type RNA - Spermatocytes [nTPM]":"20.7","Single Cell Type RNA - Spermatogonia [nTPM]":"77.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"228.8","Single Cell Type RNA - T-cells [nTPM]":"16.3","Single Cell Type RNA - Theca cells [nTPM]":"114.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"69.8"},{"Gene":"GGH","Gene synonym":[],"Ensembl":"ENSG00000137563","Gene description":"Gamma-glutamyl hydrolase","Uniprot":["Q92820"],"Chromosome":"8","Position":"63014881-63039407","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"125.7","liver":"188.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"510.3","Early spermatids":"471.0","Extravillous trophoblasts":"273.4","Proximal tubular cells":"340.8","Syncytiotrophoblasts":"754.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"30.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"30.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019296","HPA025226"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB019296":null,"HPA025226":"AB_1849645"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.8","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"11.1","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"43.7","Tissue RNA - breast [nTPM]":"16.5","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"14.3","Tissue RNA - cervix [nTPM]":"5.9","Tissue RNA - choroid plexus [nTPM]":"13.1","Tissue RNA - colon [nTPM]":"54.3","Tissue RNA - duodenum [nTPM]":"11.3","Tissue RNA - endometrium 1 [nTPM]":"6.3","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"4.3","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"12.3","Tissue RNA - kidney [nTPM]":"125.7","Tissue RNA - liver [nTPM]":"188.6","Tissue RNA - lung [nTPM]":"8.0","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"11.1","Tissue RNA - ovary [nTPM]":"3.1","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"54.9","Tissue RNA - pons [nTPM]":"13.7","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"74.4","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"27.2","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"11.6","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"33.9","Tissue RNA - thalamus [nTPM]":"14.4","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"22.5","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"110.5","Cell RNA - A549 [nTPM]":"97.6","Cell RNA - AF22 [nTPM]":"97.4","Cell RNA - AN3-CA [nTPM]":"15.7","Cell RNA - ASC diff [nTPM]":"94.1","Cell RNA - ASC TERT1 [nTPM]":"39.6","Cell RNA - BEWO [nTPM]":"69.6","Cell RNA - BJ [nTPM]":"64.3","Cell RNA - BJ hTERT+ [nTPM]":"105.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"94.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.7","Cell RNA - CACO-2 [nTPM]":"144.5","Cell RNA - CAPAN-2 [nTPM]":"183.8","Cell RNA - Daudi [nTPM]":"69.8","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"77.1","Cell RNA - GAMG [nTPM]":"166.8","Cell RNA - HaCaT [nTPM]":"87.2","Cell RNA - HAP1 [nTPM]":"97.2","Cell RNA - HBEC3-KT [nTPM]":"101.9","Cell RNA - HBF TERT88 [nTPM]":"138.9","Cell RNA - HDLM-2 [nTPM]":"139.0","Cell RNA - HEK 293 [nTPM]":"71.6","Cell RNA - HEL [nTPM]":"112.3","Cell RNA - HeLa [nTPM]":"50.3","Cell RNA - Hep G2 [nTPM]":"105.1","Cell RNA - HHSteC [nTPM]":"17.6","Cell RNA - HL-60 [nTPM]":"53.5","Cell RNA - HMC-1 [nTPM]":"65.9","Cell RNA - HSkMC [nTPM]":"29.1","Cell RNA - hTCEpi [nTPM]":"29.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.9","Cell RNA - hTERT-HME1 [nTPM]":"50.7","Cell RNA - hTERT-RPE1 [nTPM]":"59.4","Cell RNA - HUVEC TERT2 [nTPM]":"116.1","Cell RNA - JURKAT [nTPM]":"66.9","Cell RNA - K-562 [nTPM]":"62.4","Cell RNA - Karpas-707 [nTPM]":"255.2","Cell RNA - LHCN-M2 [nTPM]":"177.3","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"28.8","Cell RNA - NB-4 [nTPM]":"71.1","Cell RNA - NTERA-2 [nTPM]":"51.0","Cell RNA - OE19 [nTPM]":"231.6","Cell RNA - PC-3 [nTPM]":"86.0","Cell RNA - REH [nTPM]":"77.6","Cell RNA - RH-30 [nTPM]":"95.2","Cell RNA - RPMI-8226 [nTPM]":"98.1","Cell RNA - RPTEC TERT1 [nTPM]":"75.8","Cell RNA - RT4 [nTPM]":"40.3","Cell RNA - SCLC-21H [nTPM]":"38.6","Cell RNA - SH-SY5Y [nTPM]":"69.9","Cell RNA - SiHa [nTPM]":"91.8","Cell RNA - SK-BR-3 [nTPM]":"103.6","Cell RNA - SK-MEL-30 [nTPM]":"98.5","Cell RNA - SuSa [nTPM]":"91.6","Cell RNA - T-47d [nTPM]":"116.6","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"65.5","Cell RNA - U-138 MG [nTPM]":"104.2","Cell RNA - U-2 OS [nTPM]":"115.6","Cell RNA - U-2197 [nTPM]":"99.4","Cell RNA - U-251 MG [nTPM]":"111.3","Cell RNA - U-266\/70 [nTPM]":"112.6","Cell RNA - U-266\/84 [nTPM]":"127.2","Cell RNA - U-698 [nTPM]":"88.3","Cell RNA - U-87 MG [nTPM]":"158.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"185.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"30.6","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"11.1","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"14.3","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"12.3","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"11.1","Brain RNA - pons [nTPM]":"13.7","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"14.4","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.3","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"26.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"66.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"31.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"510.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"471.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"62.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"273.4","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"21.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"219.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"70.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.5","Single Cell Type RNA - Late spermatids [nTPM]":"154.2","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"32.1","Single Cell Type RNA - Muller glia cells [nTPM]":"23.1","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"23.7","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"106.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"340.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"80.3","Single Cell Type RNA - Spermatogonia [nTPM]":"133.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"754.5","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"102.0","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"GLDC","Gene synonym":["GCSP","NKH"],"Ensembl":"ENSG00000178445","Gene description":"Glycine decarboxylase","Uniprot":["P23378"],"Chromosome":"9","Position":"6532467-6645729","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"173.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"31.3","Cytotrophoblasts":"79.0","Extravillous trophoblasts":"41.6","Hepatocytes":"120.5","Oligodendrocyte precursor cells":"52.3","Proximal tubular cells":"31.6","Syncytiotrophoblasts":"46.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"41.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"235.7","CACO-2":"58.2","HMC-1":"45.6","RPTEC TERT1":"95.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002318","HPA052887"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA002318":"AB_1849700","HPA052887":"AB_2681980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"15.3","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"14.8","Tissue RNA - hypothalamus [nTPM]":"14.4","Tissue RNA - kidney [nTPM]":"38.2","Tissue RNA - liver [nTPM]":"173.5","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"14.0","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"13.1","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"235.7","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"58.2","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"5.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"38.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"45.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"95.4","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"22.6","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"13.9","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"34.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"15.3","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"14.8","Brain RNA - hypothalamus [nTPM]":"14.4","Brain RNA - medulla oblongata [nTPM]":"14.0","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"13.1","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"120.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"GPHN","Gene synonym":["KIAA1385"],"Ensembl":"ENSG00000171723","Gene description":"Gephyrin","Uniprot":["Q9NQX3"],"Chromosome":"14","Position":"66507407-67181803","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"62.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"493.0","Excitatory neurons":"686.5","Inhibitory neurons":"866.7","Oligodendrocyte precursor cells":"576.1","Oligodendrocytes":"597.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003116","CAB004419","HPA024694"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6900","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004419":"AB_627670","HPA003116":"AB_1078963","HPA024694":"AB_1849616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.61e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"11.1","Tissue RNA - amygdala [nTPM]":"35.5","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"36.0","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"48.4","Tissue RNA - cerebral cortex [nTPM]":"54.1","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"36.1","Tissue RNA - hypothalamus [nTPM]":"37.6","Tissue RNA - kidney [nTPM]":"25.3","Tissue RNA - liver [nTPM]":"62.4","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"3.8","Tissue RNA - medulla oblongata [nTPM]":"32.7","Tissue RNA - midbrain [nTPM]":"35.3","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"13.6","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"32.3","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"24.5","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"9.0","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"14.7","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"34.6","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"39.5","Cell RNA - A-431 [nTPM]":"39.9","Cell RNA - A549 [nTPM]":"8.8","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"15.9","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"11.1","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.2","Cell RNA - CACO-2 [nTPM]":"2.8","Cell RNA - CAPAN-2 [nTPM]":"17.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"13.1","Cell RNA - HAP1 [nTPM]":"17.0","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"18.9","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"15.8","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"9.1","Cell RNA - HMC-1 [nTPM]":"15.8","Cell RNA - HSkMC [nTPM]":"13.3","Cell RNA - hTCEpi [nTPM]":"13.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.9","Cell RNA - hTERT-HME1 [nTPM]":"16.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.8","Cell RNA - JURKAT [nTPM]":"13.8","Cell RNA - K-562 [nTPM]":"9.3","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"7.1","Cell RNA - MCF7 [nTPM]":"19.2","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"28.3","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"32.5","Cell RNA - RPMI-8226 [nTPM]":"13.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.7","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"10.2","Cell RNA - SK-BR-3 [nTPM]":"31.6","Cell RNA - SK-MEL-30 [nTPM]":"12.4","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"18.5","Cell RNA - THP-1 [nTPM]":"11.5","Cell RNA - TIME [nTPM]":"6.7","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"11.3","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"22.8","Cell RNA - U-266\/84 [nTPM]":"9.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"10.5","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"3.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"35.5","Brain RNA - basal ganglia [nTPM]":"36.0","Brain RNA - cerebellum [nTPM]":"48.4","Brain RNA - cerebral cortex [nTPM]":"54.1","Brain RNA - hippocampal formation [nTPM]":"36.1","Brain RNA - hypothalamus [nTPM]":"37.6","Brain RNA - medulla oblongata [nTPM]":"32.7","Brain RNA - midbrain [nTPM]":"35.3","Brain RNA - pons [nTPM]":"32.3","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"34.6","Brain RNA - white matter [nTPM]":"39.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"493.0","Single Cell Type RNA - B-cells [nTPM]":"11.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"34.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"686.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"47.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"866.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"4.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"148.0","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"576.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"597.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.8","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"MOCS1","Gene synonym":["MOCOD"],"Ensembl":"ENSG00000124615","Gene description":"Molybdenum cofactor synthesis 1","Uniprot":["Q9NZB8"],"Chromosome":"6","Position":"39899578-39934551","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"33.7","Hepatocytes":"36.2","Sertoli cells":"78.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"40.4","JURKAT":"51.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045783","HPA058177","HPA075505"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045783":"AB_10960058","HPA058177":"AB_2683629","HPA075505":"AB_2686751"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.7","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"17.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"26.8","Tissue RNA - cerebellum [nTPM]":"16.8","Tissue RNA - cerebral cortex [nTPM]":"14.7","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"11.7","Tissue RNA - duodenum [nTPM]":"16.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"10.1","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"22.0","Tissue RNA - hippocampal formation [nTPM]":"12.7","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"40.3","Tissue RNA - lung [nTPM]":"22.9","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"18.8","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"35.6","Tissue RNA - pons [nTPM]":"16.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"25.7","Tissue RNA - skin 1 [nTPM]":"7.3","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"15.6","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"17.3","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"45.0","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"11.4","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"8.7","Cell RNA - BJ hTERT+ [nTPM]":"15.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"40.4","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.4","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"8.2","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"13.7","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"12.0","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"4.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"10.1","Cell RNA - JURKAT [nTPM]":"51.1","Cell RNA - K-562 [nTPM]":"8.4","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"16.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"6.3","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"7.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"5.2","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"16.2","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"7.7","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"17.9","Brain RNA - cerebellum [nTPM]":"16.8","Brain RNA - cerebral cortex [nTPM]":"14.7","Brain RNA - hippocampal formation [nTPM]":"12.7","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"18.8","Brain RNA - pons [nTPM]":"16.2","Brain RNA - spinal cord [nTPM]":"15.6","Brain RNA - thalamus [nTPM]":"17.3","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"36.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.9","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"MOCS2","Gene synonym":["MOCO1","MOCS2A","MOCS2B"],"Ensembl":"ENSG00000164172","Gene description":"Molybdenum cofactor synthesis 2","Uniprot":["O96007","O96033"],"Chromosome":"5","Position":"53095679-53110063","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"573.2","Proximal tubular cells":"281.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037679","HPA037680"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear speckles"],"Antibody RRID":{"HPA037679":"AB_2675604","HPA037680":"AB_10673635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.7","Tissue RNA - adrenal gland [nTPM]":"79.4","Tissue RNA - amygdala [nTPM]":"79.1","Tissue RNA - appendix [nTPM]":"24.9","Tissue RNA - basal ganglia [nTPM]":"84.9","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"42.1","Tissue RNA - cerebellum [nTPM]":"80.3","Tissue RNA - cerebral cortex [nTPM]":"107.6","Tissue RNA - cervix [nTPM]":"34.7","Tissue RNA - choroid plexus [nTPM]":"74.4","Tissue RNA - colon [nTPM]":"41.9","Tissue RNA - duodenum [nTPM]":"40.8","Tissue RNA - endometrium 1 [nTPM]":"30.0","Tissue RNA - epididymis [nTPM]":"45.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"26.5","Tissue RNA - gallbladder [nTPM]":"31.3","Tissue RNA - heart muscle [nTPM]":"87.0","Tissue RNA - hippocampal formation [nTPM]":"84.3","Tissue RNA - hypothalamus [nTPM]":"86.3","Tissue RNA - kidney [nTPM]":"114.8","Tissue RNA - liver [nTPM]":"126.2","Tissue RNA - lung [nTPM]":"28.2","Tissue RNA - lymph node [nTPM]":"26.1","Tissue RNA - medulla oblongata [nTPM]":"79.2","Tissue RNA - midbrain [nTPM]":"80.5","Tissue RNA - ovary [nTPM]":"43.5","Tissue RNA - pancreas [nTPM]":"42.4","Tissue RNA - parathyroid gland [nTPM]":"89.6","Tissue RNA - pituitary gland [nTPM]":"30.5","Tissue RNA - placenta [nTPM]":"35.9","Tissue RNA - pons [nTPM]":"82.4","Tissue RNA - prostate [nTPM]":"36.8","Tissue RNA - rectum [nTPM]":"32.3","Tissue RNA - retina [nTPM]":"59.3","Tissue RNA - salivary gland [nTPM]":"48.9","Tissue RNA - seminal vesicle [nTPM]":"44.9","Tissue RNA - skeletal muscle [nTPM]":"109.3","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"40.2","Tissue RNA - smooth muscle [nTPM]":"34.4","Tissue RNA - spinal cord [nTPM]":"85.6","Tissue RNA - spleen [nTPM]":"23.6","Tissue RNA - stomach 1 [nTPM]":"37.2","Tissue RNA - testis [nTPM]":"26.0","Tissue RNA - thalamus [nTPM]":"88.0","Tissue RNA - thymus [nTPM]":"28.3","Tissue RNA - thyroid gland [nTPM]":"55.4","Tissue RNA - tongue [nTPM]":"111.8","Tissue RNA - tonsil [nTPM]":"25.2","Tissue RNA - urinary bladder [nTPM]":"30.8","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"87.4","Cell RNA - A-431 [nTPM]":"79.4","Cell RNA - A549 [nTPM]":"62.7","Cell RNA - AF22 [nTPM]":"42.9","Cell RNA - AN3-CA [nTPM]":"109.9","Cell RNA - ASC diff [nTPM]":"85.0","Cell RNA - ASC TERT1 [nTPM]":"83.2","Cell RNA - BEWO [nTPM]":"51.6","Cell RNA - BJ [nTPM]":"99.5","Cell RNA - BJ hTERT+ [nTPM]":"91.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.8","Cell RNA - CACO-2 [nTPM]":"79.7","Cell RNA - CAPAN-2 [nTPM]":"56.5","Cell RNA - Daudi [nTPM]":"76.7","Cell RNA - EFO-21 [nTPM]":"143.5","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"127.1","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"91.7","Cell RNA - HBEC3-KT [nTPM]":"96.7","Cell RNA - HBF TERT88 [nTPM]":"117.2","Cell RNA - HDLM-2 [nTPM]":"19.6","Cell RNA - HEK 293 [nTPM]":"84.8","Cell RNA - HEL [nTPM]":"61.7","Cell RNA - HeLa [nTPM]":"58.2","Cell RNA - Hep G2 [nTPM]":"75.9","Cell RNA - HHSteC [nTPM]":"94.4","Cell RNA - HL-60 [nTPM]":"65.0","Cell RNA - HMC-1 [nTPM]":"43.0","Cell RNA - HSkMC [nTPM]":"65.1","Cell RNA - hTCEpi [nTPM]":"41.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.7","Cell RNA - hTERT-HME1 [nTPM]":"83.5","Cell RNA - hTERT-RPE1 [nTPM]":"81.0","Cell RNA - HUVEC TERT2 [nTPM]":"85.1","Cell RNA - JURKAT [nTPM]":"101.4","Cell RNA - K-562 [nTPM]":"58.7","Cell RNA - Karpas-707 [nTPM]":"44.2","Cell RNA - LHCN-M2 [nTPM]":"129.5","Cell RNA - MCF7 [nTPM]":"115.5","Cell RNA - MOLT-4 [nTPM]":"72.7","Cell RNA - NB-4 [nTPM]":"31.8","Cell RNA - NTERA-2 [nTPM]":"37.0","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"130.1","Cell RNA - REH [nTPM]":"36.0","Cell RNA - RH-30 [nTPM]":"93.0","Cell RNA - RPMI-8226 [nTPM]":"67.0","Cell RNA - RPTEC TERT1 [nTPM]":"144.1","Cell RNA - RT4 [nTPM]":"56.6","Cell RNA - SCLC-21H [nTPM]":"29.4","Cell RNA - SH-SY5Y [nTPM]":"33.7","Cell RNA - SiHa [nTPM]":"69.4","Cell RNA - SK-BR-3 [nTPM]":"57.3","Cell RNA - SK-MEL-30 [nTPM]":"72.9","Cell RNA - SuSa [nTPM]":"56.9","Cell RNA - T-47d [nTPM]":"107.2","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"55.6","Cell RNA - U-138 MG [nTPM]":"76.9","Cell RNA - U-2 OS [nTPM]":"81.0","Cell RNA - U-2197 [nTPM]":"69.1","Cell RNA - U-251 MG [nTPM]":"120.5","Cell RNA - U-266\/70 [nTPM]":"49.4","Cell RNA - U-266\/84 [nTPM]":"84.8","Cell RNA - U-698 [nTPM]":"91.5","Cell RNA - U-87 MG [nTPM]":"106.7","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"125.1","Blood RNA - basophil [nTPM]":"14.5","Blood RNA - classical monocyte [nTPM]":"21.8","Blood RNA - eosinophil [nTPM]":"15.6","Blood RNA - gdT-cell [nTPM]":"36.9","Blood RNA - intermediate monocyte [nTPM]":"26.9","Blood RNA - MAIT T-cell [nTPM]":"46.2","Blood RNA - memory B-cell [nTPM]":"37.5","Blood RNA - memory CD4 T-cell [nTPM]":"42.7","Blood RNA - memory CD8 T-cell [nTPM]":"42.8","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"40.5","Blood RNA - naive CD4 T-cell [nTPM]":"55.3","Blood RNA - naive CD8 T-cell [nTPM]":"49.2","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"43.5","Blood RNA - non-classical monocyte [nTPM]":"25.4","Blood RNA - plasmacytoid DC [nTPM]":"27.8","Blood RNA - T-reg [nTPM]":"44.9","Blood RNA - total PBMC [nTPM]":"28.9","Brain RNA - amygdala [nTPM]":"79.1","Brain RNA - basal ganglia [nTPM]":"84.9","Brain RNA - cerebellum [nTPM]":"80.3","Brain RNA - cerebral cortex [nTPM]":"107.6","Brain RNA - hippocampal formation [nTPM]":"84.3","Brain RNA - hypothalamus [nTPM]":"86.3","Brain RNA - medulla oblongata [nTPM]":"79.2","Brain RNA - midbrain [nTPM]":"80.5","Brain RNA - pons [nTPM]":"82.4","Brain RNA - spinal cord [nTPM]":"85.6","Brain RNA - thalamus [nTPM]":"88.0","Brain RNA - white matter [nTPM]":"87.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"23.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"30.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"122.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"37.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"95.4","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"573.2","Single Cell Type RNA - Ductal cells [nTPM]":"43.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"37.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.4","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.3","Single Cell Type RNA - Fibroblasts [nTPM]":"55.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.8","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"38.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"132.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.7","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"31.2","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"50.7","Single Cell Type RNA - Macrophages [nTPM]":"28.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"67.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.1","Single Cell Type RNA - Paneth cells [nTPM]":"18.2","Single Cell Type RNA - Peritubular cells [nTPM]":"68.8","Single Cell Type RNA - Plasma cells [nTPM]":"26.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"65.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"281.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.4","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"62.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - T-cells [nTPM]":"25.8","Single Cell Type RNA - Theca cells [nTPM]":"64.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.9","Single Cell Type RNA - Urothelial cells [nTPM]":"34.5"},{"Gene":"MTHFD1","Gene synonym":["MTHFC","MTHFD"],"Ensembl":"ENSG00000100714","Gene description":"Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1","Uniprot":[],"Chromosome":"14","Position":"64388031-64463457","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"356.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"142.9","Proximal tubular cells":"75.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000704","HPA001290","HPA015006","HPA050052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000704":"AB_1079424","HPA001290":"AB_1854177","HPA015006":"AB_1854178","HPA050052":"AB_2680998"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.4","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"27.0","Tissue RNA - breast [nTPM]":"29.8","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"15.0","Tissue RNA - colon [nTPM]":"23.3","Tissue RNA - duodenum [nTPM]":"19.7","Tissue RNA - endometrium 1 [nTPM]":"16.1","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"25.1","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"28.1","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"55.3","Tissue RNA - liver [nTPM]":"356.9","Tissue RNA - lung [nTPM]":"15.4","Tissue RNA - lymph node [nTPM]":"23.6","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"27.5","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"7.0","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"13.8","Tissue RNA - skeletal muscle [nTPM]":"64.1","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"20.0","Tissue RNA - spinal cord [nTPM]":"7.2","Tissue RNA - spleen [nTPM]":"14.5","Tissue RNA - stomach 1 [nTPM]":"17.9","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"30.2","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"61.9","Tissue RNA - tonsil [nTPM]":"27.7","Tissue RNA - urinary bladder [nTPM]":"18.6","Tissue RNA - vagina [nTPM]":"16.6","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"294.1","Cell RNA - A549 [nTPM]":"164.9","Cell RNA - AF22 [nTPM]":"58.5","Cell RNA - AN3-CA [nTPM]":"143.6","Cell RNA - ASC diff [nTPM]":"70.5","Cell RNA - ASC TERT1 [nTPM]":"53.4","Cell RNA - BEWO [nTPM]":"95.7","Cell RNA - BJ [nTPM]":"106.4","Cell RNA - BJ hTERT+ [nTPM]":"83.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"148.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"147.4","Cell RNA - CACO-2 [nTPM]":"161.2","Cell RNA - CAPAN-2 [nTPM]":"144.2","Cell RNA - Daudi [nTPM]":"103.3","Cell RNA - EFO-21 [nTPM]":"49.6","Cell RNA - fHDF\/TERT166 [nTPM]":"67.1","Cell RNA - GAMG [nTPM]":"68.3","Cell RNA - HaCaT [nTPM]":"146.0","Cell RNA - HAP1 [nTPM]":"177.6","Cell RNA - HBEC3-KT [nTPM]":"111.2","Cell RNA - HBF TERT88 [nTPM]":"160.4","Cell RNA - HDLM-2 [nTPM]":"107.3","Cell RNA - HEK 293 [nTPM]":"117.9","Cell RNA - HEL [nTPM]":"122.2","Cell RNA - HeLa [nTPM]":"143.5","Cell RNA - Hep G2 [nTPM]":"131.8","Cell RNA - HHSteC [nTPM]":"50.6","Cell RNA - HL-60 [nTPM]":"104.5","Cell RNA - HMC-1 [nTPM]":"81.2","Cell RNA - HSkMC [nTPM]":"43.0","Cell RNA - hTCEpi [nTPM]":"37.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"124.3","Cell RNA - hTERT-HME1 [nTPM]":"66.4","Cell RNA - hTERT-RPE1 [nTPM]":"57.5","Cell RNA - HUVEC TERT2 [nTPM]":"93.1","Cell RNA - JURKAT [nTPM]":"98.1","Cell RNA - K-562 [nTPM]":"108.5","Cell RNA - Karpas-707 [nTPM]":"98.7","Cell RNA - LHCN-M2 [nTPM]":"114.7","Cell RNA - MCF7 [nTPM]":"270.1","Cell RNA - MOLT-4 [nTPM]":"179.9","Cell RNA - NB-4 [nTPM]":"62.3","Cell RNA - NTERA-2 [nTPM]":"118.0","Cell RNA - OE19 [nTPM]":"186.5","Cell RNA - PC-3 [nTPM]":"160.4","Cell RNA - REH [nTPM]":"138.3","Cell RNA - RH-30 [nTPM]":"201.2","Cell RNA - RPMI-8226 [nTPM]":"114.4","Cell RNA - RPTEC TERT1 [nTPM]":"110.5","Cell RNA - RT4 [nTPM]":"160.9","Cell RNA - SCLC-21H [nTPM]":"128.7","Cell RNA - SH-SY5Y [nTPM]":"49.0","Cell RNA - SiHa [nTPM]":"183.7","Cell RNA - SK-BR-3 [nTPM]":"111.4","Cell RNA - SK-MEL-30 [nTPM]":"58.3","Cell RNA - SuSa [nTPM]":"54.0","Cell RNA - T-47d [nTPM]":"164.4","Cell RNA - THP-1 [nTPM]":"58.6","Cell RNA - TIME [nTPM]":"51.5","Cell RNA - U-138 MG [nTPM]":"115.1","Cell RNA - U-2 OS [nTPM]":"184.1","Cell RNA - U-2197 [nTPM]":"102.2","Cell RNA - U-251 MG [nTPM]":"134.2","Cell RNA - U-266\/70 [nTPM]":"58.8","Cell RNA - U-266\/84 [nTPM]":"65.6","Cell RNA - U-698 [nTPM]":"177.9","Cell RNA - U-87 MG [nTPM]":"107.4","Cell RNA - U-937 [nTPM]":"125.2","Cell RNA - WM-115 [nTPM]":"134.8","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"9.7","Blood RNA - intermediate monocyte [nTPM]":"19.5","Blood RNA - MAIT T-cell [nTPM]":"13.0","Blood RNA - memory B-cell [nTPM]":"27.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"12.3","Blood RNA - myeloid DC [nTPM]":"17.7","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"10.7","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"16.7","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"19.5","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.0","Brain RNA - spinal cord [nTPM]":"7.2","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"16.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.6","Single Cell Type RNA - dendritic cells [nTPM]":"10.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"50.7","Single Cell Type RNA - Granulosa cells [nTPM]":"27.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"142.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"12.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"24.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"75.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"8.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"MTHFD1L","Gene synonym":["DKFZP586G1517","FLJ21145","FTHFSDC1"],"Ensembl":"ENSG00000120254","Gene description":"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like","Uniprot":["Q6UB35"],"Chromosome":"6","Position":"150865679-151101887","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"84.0","Extravillous trophoblasts":"166.5","Granulosa cells":"86.9","Microglial cells":"126.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1.1","T-cells":"1.8"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015006","HPA029040","HPA029041","HPA050052","HPA074911"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"89000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015006":"AB_1854178","HPA029040":"AB_2672879","HPA029041":"AB_2672880","HPA050052":"AB_2680998","HPA074911":"AB_2686723"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-5"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"13.2","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"25.1","Tissue RNA - cerebral cortex [nTPM]":"7.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"10.1","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"6.8","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"14.3","Tissue RNA - pons [nTPM]":"11.0","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"7.5","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"15.4","Cell RNA - A-431 [nTPM]":"40.6","Cell RNA - A549 [nTPM]":"35.1","Cell RNA - AF22 [nTPM]":"44.9","Cell RNA - AN3-CA [nTPM]":"110.0","Cell RNA - ASC diff [nTPM]":"11.5","Cell RNA - ASC TERT1 [nTPM]":"40.0","Cell RNA - BEWO [nTPM]":"108.4","Cell RNA - BJ [nTPM]":"63.0","Cell RNA - BJ hTERT+ [nTPM]":"68.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"75.7","Cell RNA - CACO-2 [nTPM]":"71.8","Cell RNA - CAPAN-2 [nTPM]":"37.4","Cell RNA - Daudi [nTPM]":"152.3","Cell RNA - EFO-21 [nTPM]":"41.1","Cell RNA - fHDF\/TERT166 [nTPM]":"96.9","Cell RNA - GAMG [nTPM]":"36.8","Cell RNA - HaCaT [nTPM]":"42.7","Cell RNA - HAP1 [nTPM]":"72.4","Cell RNA - HBEC3-KT [nTPM]":"61.8","Cell RNA - HBF TERT88 [nTPM]":"76.8","Cell RNA - HDLM-2 [nTPM]":"63.4","Cell RNA - HEK 293 [nTPM]":"65.3","Cell RNA - HEL [nTPM]":"62.7","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"66.1","Cell RNA - HHSteC [nTPM]":"72.4","Cell RNA - HL-60 [nTPM]":"115.7","Cell RNA - HMC-1 [nTPM]":"9.8","Cell RNA - HSkMC [nTPM]":"47.7","Cell RNA - hTCEpi [nTPM]":"76.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.6","Cell RNA - hTERT-HME1 [nTPM]":"109.8","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"105.5","Cell RNA - JURKAT [nTPM]":"81.6","Cell RNA - K-562 [nTPM]":"150.9","Cell RNA - Karpas-707 [nTPM]":"76.2","Cell RNA - LHCN-M2 [nTPM]":"65.0","Cell RNA - MCF7 [nTPM]":"86.1","Cell RNA - MOLT-4 [nTPM]":"57.1","Cell RNA - NB-4 [nTPM]":"23.9","Cell RNA - NTERA-2 [nTPM]":"45.5","Cell RNA - OE19 [nTPM]":"40.7","Cell RNA - PC-3 [nTPM]":"32.1","Cell RNA - REH [nTPM]":"67.2","Cell RNA - RH-30 [nTPM]":"33.2","Cell RNA - RPMI-8226 [nTPM]":"67.1","Cell RNA - RPTEC TERT1 [nTPM]":"42.1","Cell RNA - RT4 [nTPM]":"19.6","Cell RNA - SCLC-21H [nTPM]":"44.1","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"83.9","Cell RNA - SK-BR-3 [nTPM]":"36.7","Cell RNA - SK-MEL-30 [nTPM]":"53.0","Cell RNA - SuSa [nTPM]":"40.6","Cell RNA - T-47d [nTPM]":"11.5","Cell RNA - THP-1 [nTPM]":"79.5","Cell RNA - TIME [nTPM]":"80.6","Cell RNA - U-138 MG [nTPM]":"41.4","Cell RNA - U-2 OS [nTPM]":"90.6","Cell RNA - U-2197 [nTPM]":"91.9","Cell RNA - U-251 MG [nTPM]":"90.5","Cell RNA - U-266\/70 [nTPM]":"62.3","Cell RNA - U-266\/84 [nTPM]":"63.5","Cell RNA - U-698 [nTPM]":"154.0","Cell RNA - U-87 MG [nTPM]":"68.8","Cell RNA - U-937 [nTPM]":"105.7","Cell RNA - WM-115 [nTPM]":"54.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"25.1","Brain RNA - cerebral cortex [nTPM]":"7.4","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"10.1","Brain RNA - pons [nTPM]":"11.0","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"15.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"47.7","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"44.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"84.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"166.5","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"86.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"3.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"59.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"73.6","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"42.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"35.1"},{"Gene":"MTHFD2","Gene synonym":[],"Ensembl":"ENSG00000065911","Gene description":"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase","Uniprot":["P13995"],"Chromosome":"2","Position":"74186172-74217565","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Hydrolase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"243.6","monocytes":"184.1","Smooth muscle cells":"239.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003684","HPA049657"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003684":"AB_425867","HPA049657":"AB_2680842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.07e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Tissue RNA - adipose tissue [nTPM]":"40.0","Tissue RNA - adrenal gland [nTPM]":"12.3","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"54.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"25.8","Tissue RNA - breast [nTPM]":"34.8","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"14.7","Tissue RNA - cervix [nTPM]":"28.5","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"30.6","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"21.5","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"23.0","Tissue RNA - fallopian tube [nTPM]":"34.2","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"16.6","Tissue RNA - kidney [nTPM]":"19.6","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"23.0","Tissue RNA - lymph node [nTPM]":"45.6","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"65.9","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"33.7","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"16.7","Tissue RNA - skeletal muscle [nTPM]":"36.7","Tissue RNA - skin 1 [nTPM]":"11.8","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"27.3","Tissue RNA - spinal cord [nTPM]":"14.8","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"36.1","Tissue RNA - testis [nTPM]":"17.7","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"28.5","Tissue RNA - thyroid gland [nTPM]":"18.5","Tissue RNA - tongue [nTPM]":"55.3","Tissue RNA - tonsil [nTPM]":"57.8","Tissue RNA - urinary bladder [nTPM]":"48.0","Tissue RNA - vagina [nTPM]":"20.5","Tissue RNA - white matter [nTPM]":"15.7","Cell RNA - A-431 [nTPM]":"197.4","Cell RNA - A549 [nTPM]":"107.8","Cell RNA - AF22 [nTPM]":"89.2","Cell RNA - AN3-CA [nTPM]":"235.6","Cell RNA - ASC diff [nTPM]":"90.0","Cell RNA - ASC TERT1 [nTPM]":"113.9","Cell RNA - BEWO [nTPM]":"186.1","Cell RNA - BJ [nTPM]":"286.2","Cell RNA - BJ hTERT+ [nTPM]":"185.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"156.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"216.7","Cell RNA - CACO-2 [nTPM]":"242.8","Cell RNA - CAPAN-2 [nTPM]":"81.8","Cell RNA - Daudi [nTPM]":"391.0","Cell RNA - EFO-21 [nTPM]":"65.4","Cell RNA - fHDF\/TERT166 [nTPM]":"154.2","Cell RNA - GAMG [nTPM]":"167.5","Cell RNA - HaCaT [nTPM]":"70.7","Cell RNA - HAP1 [nTPM]":"296.7","Cell RNA - HBEC3-KT [nTPM]":"142.0","Cell RNA - HBF TERT88 [nTPM]":"314.9","Cell RNA - HDLM-2 [nTPM]":"248.9","Cell RNA - HEK 293 [nTPM]":"100.9","Cell RNA - HEL [nTPM]":"424.6","Cell RNA - HeLa [nTPM]":"55.4","Cell RNA - Hep G2 [nTPM]":"181.9","Cell RNA - HHSteC [nTPM]":"319.8","Cell RNA - HL-60 [nTPM]":"360.1","Cell RNA - HMC-1 [nTPM]":"234.8","Cell RNA - HSkMC [nTPM]":"202.9","Cell RNA - hTCEpi [nTPM]":"423.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"188.5","Cell RNA - hTERT-HME1 [nTPM]":"794.4","Cell RNA - hTERT-RPE1 [nTPM]":"74.8","Cell RNA - HUVEC TERT2 [nTPM]":"99.0","Cell RNA - JURKAT [nTPM]":"636.5","Cell RNA - K-562 [nTPM]":"192.2","Cell RNA - Karpas-707 [nTPM]":"548.0","Cell RNA - LHCN-M2 [nTPM]":"157.5","Cell RNA - MCF7 [nTPM]":"159.6","Cell RNA - MOLT-4 [nTPM]":"209.5","Cell RNA - NB-4 [nTPM]":"261.0","Cell RNA - NTERA-2 [nTPM]":"161.1","Cell RNA - OE19 [nTPM]":"293.3","Cell RNA - PC-3 [nTPM]":"95.8","Cell RNA - REH [nTPM]":"222.6","Cell RNA - RH-30 [nTPM]":"266.3","Cell RNA - RPMI-8226 [nTPM]":"339.4","Cell RNA - RPTEC TERT1 [nTPM]":"72.0","Cell RNA - RT4 [nTPM]":"80.8","Cell RNA - SCLC-21H [nTPM]":"198.2","Cell RNA - SH-SY5Y [nTPM]":"143.8","Cell RNA - SiHa [nTPM]":"97.4","Cell RNA - SK-BR-3 [nTPM]":"238.3","Cell RNA - SK-MEL-30 [nTPM]":"549.7","Cell RNA - SuSa [nTPM]":"56.9","Cell RNA - T-47d [nTPM]":"208.5","Cell RNA - THP-1 [nTPM]":"324.4","Cell RNA - TIME [nTPM]":"52.9","Cell RNA - U-138 MG [nTPM]":"39.1","Cell RNA - U-2 OS [nTPM]":"359.9","Cell RNA - U-2197 [nTPM]":"97.7","Cell RNA - U-251 MG [nTPM]":"286.5","Cell RNA - U-266\/70 [nTPM]":"484.5","Cell RNA - U-266\/84 [nTPM]":"257.6","Cell RNA - U-698 [nTPM]":"379.2","Cell RNA - U-87 MG [nTPM]":"111.4","Cell RNA - U-937 [nTPM]":"304.1","Cell RNA - WM-115 [nTPM]":"132.5","Blood RNA - basophil [nTPM]":"43.9","Blood RNA - classical monocyte [nTPM]":"24.0","Blood RNA - eosinophil [nTPM]":"31.1","Blood RNA - gdT-cell [nTPM]":"8.5","Blood RNA - intermediate monocyte [nTPM]":"56.6","Blood RNA - MAIT T-cell [nTPM]":"13.0","Blood RNA - memory B-cell [nTPM]":"13.4","Blood RNA - memory CD4 T-cell [nTPM]":"15.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"34.9","Blood RNA - naive B-cell [nTPM]":"12.2","Blood RNA - naive CD4 T-cell [nTPM]":"11.5","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"57.0","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"36.8","Blood RNA - total PBMC [nTPM]":"22.0","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"14.7","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"16.6","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"14.8","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"15.7","Single Cell Type RNA - Adipocytes [nTPM]":"19.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"49.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"28.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.5","Single Cell Type RNA - dendritic cells [nTPM]":"48.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"55.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"104.7","Single Cell Type RNA - Endothelial cells [nTPM]":"35.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.1","Single Cell Type RNA - Erythroid cells [nTPM]":"104.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"56.9","Single Cell Type RNA - Fibroblasts [nTPM]":"45.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.7","Single Cell Type RNA - granulocytes [nTPM]":"53.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"66.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.0","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"61.6","Single Cell Type RNA - Langerhans cells [nTPM]":"243.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"100.6","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"184.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.5","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"141.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"126.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"239.0","Single Cell Type RNA - Spermatocytes [nTPM]":"36.5","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"71.4","Single Cell Type RNA - Theca cells [nTPM]":"21.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.0","Single Cell Type RNA - Urothelial cells [nTPM]":"64.2"},{"Gene":"MTHFD2L","Gene synonym":["MGC72244"],"Ensembl":"ENSG00000163738","Gene description":"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like","Uniprot":["Q9H903"],"Chromosome":"4","Position":"74114174-74303099","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Amino-acid biosynthesis","Histidine biosynthesis","Methionine biosynthesis","One-carbon metabolism","Purine biosynthesis"],"Molecular function":["Hydrolase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035434"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035434":"AB_10601038"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"3.3","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"1.4","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"8.5","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"1.3","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"3.6","Cell RNA - ASC diff [nTPM]":"1.4","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.4","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"3.7","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"2.6","Cell RNA - HHSteC [nTPM]":"2.4","Cell RNA - HL-60 [nTPM]":"5.8","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"6.7","Cell RNA - K-562 [nTPM]":"6.6","Cell RNA - Karpas-707 [nTPM]":"3.6","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"2.7","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"8.3","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"10.9","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.2","Cell RNA - RT4 [nTPM]":"1.4","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"8.0","Cell RNA - SiHa [nTPM]":"1.8","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"4.3","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"4.9","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"5.6","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"5.0","Cell RNA - U-698 [nTPM]":"8.8","Cell RNA - U-87 MG [nTPM]":"15.5","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"8.5","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.6","Single Cell Type RNA - Astrocytes [nTPM]":"57.5","Single Cell Type RNA - B-cells [nTPM]":"18.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"90.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"27.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"49.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"24.0","Single Cell Type RNA - Early spermatids [nTPM]":"85.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"19.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.2","Single Cell Type RNA - Erythroid cells [nTPM]":"44.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.4","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"35.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"104.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.7","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"23.0","Single Cell Type RNA - Late spermatids [nTPM]":"23.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"17.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"73.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"19.4","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"20.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"69.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"30.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.1","Single Cell Type RNA - Spermatocytes [nTPM]":"8.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"11.1","Single Cell Type RNA - Theca cells [nTPM]":"36.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.4","Single Cell Type RNA - Urothelial cells [nTPM]":"71.9"},{"Gene":"MTHFR","Gene synonym":[],"Ensembl":"ENSG00000177000","Gene description":"Methylenetetrahydrofolate reductase","Uniprot":["P42898"],"Chromosome":"1","Position":"11785723-11806455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Oxidoreductase"],"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"44.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063389","HPA076180","HPA077255"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA063389":"AB_2685001","HPA076180":null,"HPA077255":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.97e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.3","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"28.9","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"12.8","Tissue RNA - cerebral cortex [nTPM]":"8.8","Tissue RNA - cervix [nTPM]":"9.0","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"11.1","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"53.5","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"10.1","Tissue RNA - heart muscle [nTPM]":"23.9","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"19.7","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"7.1","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"8.7","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"17.9","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"5.1","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"16.8","Tissue RNA - tonsil [nTPM]":"12.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"2.2","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"12.3","Cell RNA - ASC diff [nTPM]":"10.2","Cell RNA - ASC TERT1 [nTPM]":"15.1","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"18.0","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"7.5","Cell RNA - GAMG [nTPM]":"16.3","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"7.7","Cell RNA - HBF TERT88 [nTPM]":"2.4","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"13.3","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"13.7","Cell RNA - HL-60 [nTPM]":"7.4","Cell RNA - HMC-1 [nTPM]":"16.4","Cell RNA - HSkMC [nTPM]":"13.6","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.0","Cell RNA - hTERT-HME1 [nTPM]":"6.4","Cell RNA - hTERT-RPE1 [nTPM]":"10.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"44.1","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"6.7","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"3.5","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"9.5","Cell RNA - PC-3 [nTPM]":"3.0","Cell RNA - REH [nTPM]":"8.9","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"20.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"11.7","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"17.6","Cell RNA - SiHa [nTPM]":"8.1","Cell RNA - SK-BR-3 [nTPM]":"7.8","Cell RNA - SK-MEL-30 [nTPM]":"10.9","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"7.2","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"9.4","Cell RNA - U-698 [nTPM]":"32.8","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"12.8","Brain RNA - cerebral cortex [nTPM]":"8.8","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"5.1","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"15.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"48.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"18.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"21.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"23.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"39.3","Single Cell Type RNA - Langerhans cells [nTPM]":"39.9","Single Cell Type RNA - Late spermatids [nTPM]":"42.4","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"32.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"26.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.9","Single Cell Type RNA - Paneth cells [nTPM]":"20.6","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"MTHFS","Gene synonym":["HsT19268"],"Ensembl":"ENSG00000136371","Gene description":"Methenyltetrahydrofolate synthetase","Uniprot":["P49914"],"Chromosome":"15","Position":"79833585-79897379","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"253.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"205.5","monocytes":"150.8","Proximal tubular cells":"201.6","Syncytiotrophoblasts":"253.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"134.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"134.1","monocytes":"49.1"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008067","HPA054177"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008067":"AB_1078882","HPA054177":"AB_2682405"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"19.0","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"9.9","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"9.0","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"19.0","Tissue RNA - hippocampal formation [nTPM]":"8.0","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"253.4","Tissue RNA - lung [nTPM]":"17.8","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"8.6","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"21.5","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"20.2","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"15.9","Tissue RNA - tongue [nTPM]":"11.1","Tissue RNA - tonsil [nTPM]":"10.8","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"12.6","Cell RNA - A549 [nTPM]":"35.8","Cell RNA - AF22 [nTPM]":"5.0","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"15.8","Cell RNA - ASC TERT1 [nTPM]":"12.0","Cell RNA - BEWO [nTPM]":"11.9","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"34.5","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"15.0","Cell RNA - HaCaT [nTPM]":"19.5","Cell RNA - HAP1 [nTPM]":"31.9","Cell RNA - HBEC3-KT [nTPM]":"10.7","Cell RNA - HBF TERT88 [nTPM]":"15.4","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"28.4","Cell RNA - HEL [nTPM]":"14.8","Cell RNA - HeLa [nTPM]":"22.9","Cell RNA - Hep G2 [nTPM]":"39.8","Cell RNA - HHSteC [nTPM]":"25.3","Cell RNA - HL-60 [nTPM]":"7.8","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"27.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.1","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"16.0","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"12.0","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"36.0","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"36.1","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"51.4","Cell RNA - PC-3 [nTPM]":"17.0","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"17.2","Cell RNA - RPMI-8226 [nTPM]":"25.8","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"34.3","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"25.1","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"43.8","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"17.3","Cell RNA - THP-1 [nTPM]":"13.0","Cell RNA - TIME [nTPM]":"3.3","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"11.1","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"7.1","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"20.2","Cell RNA - U-698 [nTPM]":"17.8","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"6.2","Blood RNA - basophil [nTPM]":"17.5","Blood RNA - classical monocyte [nTPM]":"25.7","Blood RNA - eosinophil [nTPM]":"73.5","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"35.3","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"13.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.9","Blood RNA - myeloid DC [nTPM]":"12.3","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"16.5","Blood RNA - naive CD8 T-cell [nTPM]":"12.6","Blood RNA - neutrophil [nTPM]":"134.1","Blood RNA - NK-cell [nTPM]":"17.8","Blood RNA - non-classical monocyte [nTPM]":"49.1","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"15.7","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"8.0","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"11.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"34.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"68.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"55.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.6","Single Cell Type RNA - Erythroid cells [nTPM]":"36.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.1","Single Cell Type RNA - Fibroblasts [nTPM]":"13.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"205.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"22.1","Single Cell Type RNA - Langerhans cells [nTPM]":"34.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"29.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"150.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"75.3","Single Cell Type RNA - Paneth cells [nTPM]":"35.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"13.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"101.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"201.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"253.8","Single Cell Type RNA - T-cells [nTPM]":"22.2","Single Cell Type RNA - Theca cells [nTPM]":"9.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.9","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"QDPR","Gene synonym":["DHPR","PKU2","SDR33C1"],"Ensembl":"ENSG00000151552","Gene description":"Quinoid dihydropteridine reductase","Uniprot":["P09417"],"Chromosome":"4","Position":"17460261-17512206","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tetrahydrobiopterin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Phenylketonuria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"752.2","choroid plexus":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"337.6","Muller glia cells":"387.2","Oligodendrocytes":"481.3","Proximal tubular cells":"527.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058951","HPA065649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA058951":"AB_2683861","HPA065649":"AB_2685526"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Tissue RNA - adipose tissue [nTPM]":"66.6","Tissue RNA - adrenal gland [nTPM]":"74.3","Tissue RNA - amygdala [nTPM]":"515.1","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"720.1","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"696.9","Tissue RNA - cerebral cortex [nTPM]":"571.9","Tissue RNA - cervix [nTPM]":"15.8","Tissue RNA - choroid plexus [nTPM]":"301.8","Tissue RNA - colon [nTPM]":"21.2","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"16.5","Tissue RNA - epididymis [nTPM]":"40.1","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"17.3","Tissue RNA - gallbladder [nTPM]":"17.7","Tissue RNA - heart muscle [nTPM]":"43.4","Tissue RNA - hippocampal formation [nTPM]":"457.6","Tissue RNA - hypothalamus [nTPM]":"578.5","Tissue RNA - kidney [nTPM]":"110.1","Tissue RNA - liver [nTPM]":"197.2","Tissue RNA - lung [nTPM]":"23.3","Tissue RNA - lymph node [nTPM]":"11.9","Tissue RNA - medulla oblongata [nTPM]":"663.0","Tissue RNA - midbrain [nTPM]":"752.2","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"28.8","Tissue RNA - parathyroid gland [nTPM]":"49.9","Tissue RNA - pituitary gland [nTPM]":"32.7","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"688.6","Tissue RNA - prostate [nTPM]":"28.7","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"40.1","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"19.5","Tissue RNA - skeletal muscle [nTPM]":"108.6","Tissue RNA - skin 1 [nTPM]":"16.2","Tissue RNA - small intestine [nTPM]":"23.9","Tissue RNA - smooth muscle [nTPM]":"17.9","Tissue RNA - spinal cord [nTPM]":"524.9","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"23.7","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"602.6","Tissue RNA - thymus [nTPM]":"13.6","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"61.2","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"15.1","Tissue RNA - white matter [nTPM]":"663.7","Cell RNA - A-431 [nTPM]":"33.1","Cell RNA - A549 [nTPM]":"62.5","Cell RNA - AF22 [nTPM]":"30.2","Cell RNA - AN3-CA [nTPM]":"35.8","Cell RNA - ASC diff [nTPM]":"66.1","Cell RNA - ASC TERT1 [nTPM]":"32.3","Cell RNA - BEWO [nTPM]":"41.5","Cell RNA - BJ [nTPM]":"43.2","Cell RNA - BJ hTERT+ [nTPM]":"22.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"52.2","Cell RNA - CAPAN-2 [nTPM]":"46.4","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"28.0","Cell RNA - fHDF\/TERT166 [nTPM]":"30.3","Cell RNA - GAMG [nTPM]":"50.8","Cell RNA - HaCaT [nTPM]":"18.4","Cell RNA - HAP1 [nTPM]":"40.3","Cell RNA - HBEC3-KT [nTPM]":"58.4","Cell RNA - HBF TERT88 [nTPM]":"33.7","Cell RNA - HDLM-2 [nTPM]":"35.3","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"128.3","Cell RNA - HHSteC [nTPM]":"37.3","Cell RNA - HL-60 [nTPM]":"46.2","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"40.8","Cell RNA - hTCEpi [nTPM]":"35.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.6","Cell RNA - hTERT-HME1 [nTPM]":"40.3","Cell RNA - hTERT-RPE1 [nTPM]":"25.9","Cell RNA - HUVEC TERT2 [nTPM]":"24.5","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"37.0","Cell RNA - Karpas-707 [nTPM]":"29.0","Cell RNA - LHCN-M2 [nTPM]":"50.6","Cell RNA - MCF7 [nTPM]":"19.2","Cell RNA - MOLT-4 [nTPM]":"65.0","Cell RNA - NB-4 [nTPM]":"77.8","Cell RNA - NTERA-2 [nTPM]":"44.8","Cell RNA - OE19 [nTPM]":"36.7","Cell RNA - PC-3 [nTPM]":"45.4","Cell RNA - REH [nTPM]":"27.0","Cell RNA - RH-30 [nTPM]":"21.0","Cell RNA - RPMI-8226 [nTPM]":"52.2","Cell RNA - RPTEC TERT1 [nTPM]":"48.2","Cell RNA - RT4 [nTPM]":"17.5","Cell RNA - SCLC-21H [nTPM]":"47.1","Cell RNA - SH-SY5Y [nTPM]":"64.3","Cell RNA - SiHa [nTPM]":"31.9","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"156.6","Cell RNA - SuSa [nTPM]":"35.0","Cell RNA - T-47d [nTPM]":"15.7","Cell RNA - THP-1 [nTPM]":"19.0","Cell RNA - TIME [nTPM]":"37.7","Cell RNA - U-138 MG [nTPM]":"23.6","Cell RNA - U-2 OS [nTPM]":"41.1","Cell RNA - U-2197 [nTPM]":"26.5","Cell RNA - U-251 MG [nTPM]":"38.2","Cell RNA - U-266\/70 [nTPM]":"43.1","Cell RNA - U-266\/84 [nTPM]":"67.7","Cell RNA - U-698 [nTPM]":"85.3","Cell RNA - U-87 MG [nTPM]":"52.0","Cell RNA - U-937 [nTPM]":"43.1","Cell RNA - WM-115 [nTPM]":"41.7","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"38.9","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"31.3","Blood RNA - intermediate monocyte [nTPM]":"61.3","Blood RNA - MAIT T-cell [nTPM]":"29.8","Blood RNA - memory B-cell [nTPM]":"18.6","Blood RNA - memory CD4 T-cell [nTPM]":"33.1","Blood RNA - memory CD8 T-cell [nTPM]":"32.3","Blood RNA - myeloid DC [nTPM]":"48.3","Blood RNA - naive B-cell [nTPM]":"18.3","Blood RNA - naive CD4 T-cell [nTPM]":"37.4","Blood RNA - naive CD8 T-cell [nTPM]":"32.6","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"48.4","Blood RNA - plasmacytoid DC [nTPM]":"115.1","Blood RNA - T-reg [nTPM]":"20.3","Blood RNA - total PBMC [nTPM]":"34.4","Brain RNA - amygdala [nTPM]":"515.1","Brain RNA - basal ganglia [nTPM]":"720.1","Brain RNA - cerebellum [nTPM]":"696.9","Brain RNA - cerebral cortex [nTPM]":"571.9","Brain RNA - hippocampal formation [nTPM]":"457.6","Brain RNA - hypothalamus [nTPM]":"578.5","Brain RNA - medulla oblongata [nTPM]":"663.0","Brain RNA - midbrain [nTPM]":"752.2","Brain RNA - pons [nTPM]":"688.6","Brain RNA - spinal cord [nTPM]":"524.9","Brain RNA - thalamus [nTPM]":"602.6","Brain RNA - white matter [nTPM]":"663.7","Single Cell Type RNA - Adipocytes [nTPM]":"20.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"14.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"36.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"74.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"174.3","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"42.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.7","Single Cell Type RNA - Hepatocytes [nTPM]":"337.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"80.3","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.1","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"38.1","Single Cell Type RNA - Langerhans cells [nTPM]":"23.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"32.2","Single Cell Type RNA - Melanocytes [nTPM]":"152.9","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"23.4","Single Cell Type RNA - Muller glia cells [nTPM]":"387.2","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"481.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"38.0","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"527.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"58.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"90.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.3"}]