Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ALDH1L1	"10-fTHF, FDH, FTHFD"	ENSG00000144908	"Aldehyde dehydrogenase 1 family member L1"	O75891	3	126103562-126197994	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 369.7"	"Group enriched"	"Detected in many"	4	"Hepatocytes: 633.3;Proximal tubular cells: 197.4"	"Cancer enriched"	"Detected in many"	4	"liver cancer: 40.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036900, HPA050139"	Enhanced	Supported	Supported	Cytosol		No	No		3000000		"Cluster 15: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 2: Hepatocytes - Metabolism"	Cytosol		"HPA036900: AB_10672273, HPA050139: AB_2681031"	"unprognostic (5.93e-2)"	"unprognostic (1.22e-1)"	"unprognostic (9.12e-2)"	"unprognostic (2.68e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.12e-2)"	"unprognostic (1.29e-1)"	"unprognostic (3.05e-2)"	"unprognostic (4.73e-2)"	"unprognostic (3.05e-3)"	"unprognostic (8.40e-2)"	"prognostic favorable (2.42e-8)"	"unprognostic (3.60e-1)"	"unprognostic (1.47e-1)"	"unprognostic (7.03e-3)"	"unprognostic (7.93e-2)"	76.4	37.2	53.4	2.0	63.2	0.4	28.8	55.9	63.6	15.6	37.7	10.1	0.2	7.2	2.5	6.6	16.0	2.3	26.5	47.5	56.2	116.6	369.7	3.1	0.3	56.7	52.9	45.3	44.3	15.1	4.5	0.0	53.0	14.6	5.4	8.7	88.6	6.9	90.7	3.5	5.6	2.0	48.4	0.4	9.5	15.0	53.9	3.7	2.6	59.9	4.6	28.3	6.4	46.0	1.3	0.0	0.0	0.0	36.5	0.0	0.4	0.3	1.5	0.4	0.6	0.0	3.2	2.6	10.2	0.0	2.1	0.4	0.6	1.5	0.7	0.0	0.2	0.1	0.3	78.1	10.6	10.6	0.2	0.3	0.8	0.0	0.0	0.3	0.0	0.0	0.0	82.0	1.6	0.0	0.0	0.2	0.3	1.1	0.0	0.1	0.2	45.0	0.7	219.1	0.4	0.3	1.3	10.6	0.0	0.6	0.1	0.0	0.3	1.4	6.2	0.0	0.1	44.8	14.8	0.4	0.2	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	53.4	63.2	55.9	63.6	47.5	56.2	56.7	52.9	53.0	48.4	53.9	46.0	0.8	0.0	6.0	92.7	4.6	0.1	53.5	9.1	1.8	0.2	14.4	2.2	16.1	38.6	44.0	12.9	0.0	0.0	0.1	7.2	72.4	2.9	22.3	57.2	5.2	4.6	1.2	34.7	0.6	5.6	0.2	9.1	0.0	3.6	27.8	12.4	17.2	633.3	0.1	0.0	3.0	17.6	2.0	24.5	1.9	35.0	26.4	9.3	3.6	3.7	0.0	40.0	0.0	11.1	0.2	2.2	0.4	22.6	0.0	12.2	0.8	197.4	32.2	1.4	6.6	10.5	5.3	1.6	4.3	1.7	0.0	0.1	2.8	0.9	5.6	61.7
ALDH1L2	"FLJ38508, mtFDH"	ENSG00000136010	"Aldehyde dehydrogenase 1 family member L2"	Q3SY69	12	105019784-105107643	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"pancreas: 40.7;salivary gland: 13.0"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA039481, HPA059282"	Approved		Enhanced	Mitochondria		No	No				"Cluster 25: Pancreas - Digestion"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 50: Fibroblasts - ECM organization"	Mitochondria		"HPA039481: AB_10795465, HPA059282: AB_2732633"	"unprognostic (5.99e-2)"	"unprognostic (1.42e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.36e-3)"	"unprognostic (1.76e-1)"	"unprognostic (8.86e-2)"	"unprognostic (1.75e-1)"	"unprognostic (2.92e-1)"	"unprognostic (5.74e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.61e-1)"	"unprognostic (8.19e-8)"	"unprognostic (3.21e-3)"	"unprognostic (1.33e-1)"	"unprognostic (2.53e-3)"	"unprognostic (2.52e-5)"	3.7	0.6	1.3	3.1	1.2	0.6	2.3	2.3	1.6	5.3	0.7	2.2	2.6	2.0	1.0	1.3	1.5	2.8	1.9	1.1	1.6	0.4	0.2	1.8	1.0	1.4	1.3	0.6	40.7	0.6	1.3	1.1	1.5	3.6	2.3	0.7	13.0	4.6	0.8	1.0	1.4	4.2	1.8	0.7	3.3	1.1	1.6	0.5	2.1	1.2	1.7	3.4	1.5	2.5	13.0	1.3	0.7	27.3	62.8	85.2	1.6	40.8	26.0	5.2	13.5	1.6	0.0	0.0	1.6	102.4	0.2	0.1	0.1	1.0	6.5	0.0	0.3	0.8	0.1	3.4	55.6	5.3	0.1	69.7	3.1	13.6	25.2	0.0	3.0	0.2	2.1	37.7	10.6	0.0	0.0	0.3	1.6	0.0	0.3	0.0	0.1	4.3	0.0	0.0	9.4	4.5	0.0	8.3	20.5	0.4	6.0	44.0	0.3	3.9	3.8	0.0	2.2	45.5	12.8	0.1	16.2	19.2	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.3	1.2	2.3	1.6	1.1	1.6	1.4	1.3	1.5	1.8	1.6	2.5	1.4	0.0	0.6	3.3	2.6	0.5	0.1	0.7	0.0	1.7	0.3	1.1	1.6	0.0	0.2	0.0	0.0	0.2	1.5	0.1	0.0	0.3	4.1	0.7	8.5	0.9	0.0	0.0	23.1	9.8	0.6	10.5	1.5	1.6	0.0	0.1	1.1	0.0	0.4	5.0	24.0	0.0	0.0	0.6	1.7	5.9	3.7	1.0	5.4	1.0	4.0	1.3	0.0	25.1	8.5	3.7	0.0	6.8	14.6	0.4	0.0	0.1	0.2	0.8	0.0	3.6	8.4	1.7	0.1	0.0	0.6	0.3	0.9	0.1	0.1	0.2
AMT	"GCST, NKH"	ENSG00000145020	Aminomethyltransferase	P48728	3	49416778-49422685	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Aminotransferase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 49.1"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 42.4;Proximal enterocytes: 33.3;Undifferentiated cells: 31.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"NK-cell: 7.9"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"BEWO: 17.1;Hep G2: 47.5;NTERA-2: 8.0;SH-SY5Y: 14.9;SuSa: 9.0"									HPA005566	Supported		Supported	Nucleoplasm,Mitochondria		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 35: Non-specific - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Mitochondria	Nucleoplasm	"HPA005566: AB_1844811"	"unprognostic (2.10e-2)"	"unprognostic (1.65e-2)"	"unprognostic (1.82e-1)"	"unprognostic (9.14e-3)"	"unprognostic (4.04e-1)"	"unprognostic (1.11e-2)"	"unprognostic (2.81e-1)"	"unprognostic (2.17e-3)"	"unprognostic (1.94e-1)"	"unprognostic (3.29e-1)"	"unprognostic (7.17e-3)"	"unprognostic (1.88e-1)"	"prognostic favorable (3.90e-8)"	"unprognostic (4.40e-1)"	"unprognostic (1.91e-1)"	"unprognostic (3.60e-1)"	"unprognostic (1.98e-3)"	4.7	12.8	9.8	1.2	10.3	8.8	5.6	10.7	11.7	11.8	13.1	12.2	13.8	6.8	8.2	3.5	10.1	5.8	21.6	9.4	9.6	23.2	49.1	5.4	2.1	9.8	10.2	12.5	19.5	14.2	11.9	2.3	9.8	11.3	11.8	6.5	10.6	8.5	3.1	4.8	12.1	3.7	9.9	6.3	11.1	3.0	10.0	3.8	5.8	4.2	1.5	8.0	6.4	9.9	0.1	0.7	1.4	0.4	0.6	0.0	17.1	0.0	0.4	0.1	0.3	0.5	0.6	0.0	0.2	0.4	0.0	0.3	0.1	0.7	0.1	0.3	0.0	0.0	0.5	47.5	1.8	0.0	0.0	0.6	1.8	0.0	0.7	1.3	0.6	0.2	0.0	0.0	0.2	0.4	0.1	0.1	8.0	0.0	0.2	0.0	0.5	1.0	0.8	0.4	0.0	14.9	0.2	0.0	1.1	9.0	0.1	0.3	0.6	0.1	0.0	0.3	0.0	1.0	0.0	0.0	0.0	0.3	0.0	0.0	2.1	3.2	0.0	1.7	0.0	0.5	0.0	0.0	4.2	0.2	1.2	0.9	0.1	7.9	0.5	0.3	0.0	1.3	9.8	10.3	10.7	11.7	9.4	9.6	9.8	10.2	9.8	9.9	10.0	9.9	1.2	3.2	9.2	11.4	3.6	2.8	12.1	3.1	3.4	17.4	1.2	1.3	21.8	14.3	6.3	0.0	20.9	25.6	1.4	13.8	0.0	0.8	2.5	0.7	1.6	3.2	12.7	8.8	8.7	0.7	8.8	4.5	15.8	1.0	7.6	2.0	3.9	42.4	5.0	8.4	8.5	18.4	2.0	3.8	2.9	1.6	10.5	2.6	5.4	7.5	1.8	26.0	7.2	6.0	6.6	0.6	18.9	6.4	1.1	6.7	33.3	1.1	6.6	19.3	6.6	5.2	3.1	1.9	0.3	2.2	2.7	10.3	3.8	1.0	31.6	10.9
DHFR		ENSG00000228716	"Dihydrofolate reductase"	P00374	5	80626226-80654983	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Methotrexate resistance, One-carbon metabolism"	"Oxidoreductase, RNA-binding"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 145.8;Spermatocytes: 132.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037129, HPA051465"	Uncertain		Approved	Mitochondria		NA	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Mitochondria		"CAB037129: AB_439683, HPA051465: AB_2681494"	"unprognostic (1.44e-2)"	"unprognostic (1.03e-2)"	"unprognostic (2.24e-3)"	"unprognostic (2.91e-3)"	"unprognostic (3.27e-1)"	"unprognostic (1.32e-1)"	"unprognostic (2.83e-2)"	"unprognostic (2.35e-2)"	"unprognostic (2.02e-2)"	"unprognostic (4.19e-3)"	"unprognostic (1.83e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.15e-2)"	"unprognostic (1.82e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.09e-1)"	25.2	5.3	15.3	20.7	16.5	54.3	12.0	15.8	21.9	8.0	13.3	21.4	24.5	8.6	7.0	14.1	7.4	8.5	7.2	13.8	15.5	21.3	60.1	7.5	41.5	16.6	16.6	6.6	3.2	9.1	6.3	14.4	16.6	8.9	25.3	10.3	6.8	9.5	19.6	9.8	25.1	12.0	16.5	10.3	12.2	18.5	15.8	60.7	8.2	25.8	39.5	10.3	5.7	17.7	98.1	66.6	164.8	122.7	30.7	32.0	60.6	76.5	58.1	130.2	149.0	63.8	114.6	196.9	32.5	44.6	106.0	67.0	214.4	98.6	208.5	88.2	132.1	94.8	104.5	59.5	6.6	111.7	40.3	22.3	9.9	116.9	13.0	22.2	63.9	142.0	108.3	146.7	133.5	98.2	276.5	44.9	83.6	48.3	38.5	176.7	323.3	194.1	75.1	61.5	134.3	93.7	107.9	49.9	54.6	83.5	98.5	108.6	38.5	41.0	62.0	116.0	148.3	68.2	146.6	210.3	91.5	222.1	107.7	0.2	0.3	0.2	0.5	0.6	0.2	0.5	0.6	0.8	0.5	0.5	0.5	0.6	0.8	0.5	0.5	0.8	0.9	0.6	15.3	16.5	15.8	21.9	13.8	15.5	16.6	16.6	16.6	16.5	15.8	17.7	4.1	6.4	11.7	4.9	21.4	6.9	6.5	6.0	4.0	3.5	8.9	8.9	13.0	4.3	6.1	14.7	2.1	35.2	7.4	19.3	9.8	7.4	7.4	10.8	7.7	7.7	4.9	145.8	7.3	3.7	47.3	12.0	11.7	8.0	2.5	22.0	10.0	48.3	44.7	3.3	7.2	19.1	4.1	18.9	4.4	6.4	14.0	12.8	0.0	4.7	7.1	14.5	13.4	3.5	6.0	4.7	10.3	16.1	60.9	2.9	26.6	40.0	6.9	3.2	13.1	9.0	12.5	132.2	49.8	21.2	5.5	13.3	11.8	12.3	38.1	12.1
DHFR2	"DHFRL1, DHFRP4, FLJ16119"	ENSG00000178700	"Dihydrofolate reductase 2"	Q86XF0	3	94047836-94063389	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 12.8;Ductal cells: 6.3;Respiratory ciliated cells: 8.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in all"	13	"hTERT-RPE1: 154.6"									HPA051465	Uncertain		Approved	Mitochondria		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 7: Non-specific - Mitochondria"	Mitochondria		"HPA051465: AB_2681494"	"unprognostic (1.16e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.10e-2)"	"unprognostic (3.50e-2)"	"unprognostic (2.07e-1)"	"unprognostic (1.38e-1)"	"unprognostic (5.92e-2)"	"unprognostic (1.33e-1)"	"unprognostic (1.12e-1)"	"unprognostic (4.62e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.52e-1)"	"prognostic favorable (2.30e-6)"	"unprognostic (1.63e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.96e-2)"	3.3	4.9	3.9	3.8	5.2	1.8	5.3	6.0	5.2	5.2	4.8	4.2	4.1	7.9	6.4	3.5	6.3	5.1	3.7	4.1	4.1	5.9	6.7	4.5	5.7	4.8	4.2	10.1	5.3	6.5	2.5	3.2	5.0	6.4	4.6	3.2	4.4	4.9	1.4	4.2	4.9	5.4	4.2	4.9	4.7	4.7	4.4	5.7	6.7	2.1	4.6	3.3	2.4	6.5	3.8	6.5	4.2	4.4	5.7	7.2	1.7	5.7	6.0	2.8	3.2	1.4	5.7	2.5	3.8	3.0	3.7	5.0	3.3	3.9	4.4	8.5	1.8	3.1	2.9	3.4	6.0	2.2	3.6	7.6	5.1	3.3	4.2	154.6	2.9	11.9	1.6	5.6	3.7	4.5	10.8	1.2	3.7	10.8	6.7	2.7	5.7	4.1	4.1	1.9	5.4	5.3	8.3	2.2	9.6	3.3	5.6	3.1	4.8	4.4	7.4	1.8	2.2	4.1	4.4	3.5	4.4	5.5	6.2	2.2	1.1	2.0	1.8	1.7	3.3	1.8	2.4	2.9	0.7	2.2	3.2	3.0	1.7	1.4	1.8	2.1	3.2	1.3	3.9	5.2	6.0	5.2	4.1	4.1	4.8	4.2	5.0	4.2	4.4	6.5	2.8	12.8	5.8	0.0	0.9	0.0	0.0	0.0	0.0	0.0	3.6	3.4	0.0	0.0	1.8	3.7	0.0	2.4	2.3	0.0	3.9	6.3	0.0	3.5	4.4	2.5	0.0	0.0	0.0	5.5	1.7	2.5	0.0	2.9	2.5	4.9	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	2.6	0.0	0.0	0.0	0.0	4.6	0.0	0.0	0.4	0.0	0.0	5.6	8.7	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.8	1.3	3.5	0.0	0.0
DLD	"DLDH, E3, GCSL, LAD, OGDC-E3"	ENSG00000091140	"Dihydrolipoamide dehydrogenase"	P09622	7	107891162-107931730	"Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"tongue: 357.0"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 356.2;Distal tubular cells: 226.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044849	Supported		Approved	Nucleoplasm,Mitochondria		NA	NA		10000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoplasm	"HPA044849: AB_2679111"	"unprognostic (2.01e-3)"	"unprognostic (2.26e-1)"	"unprognostic (1.27e-2)"	"unprognostic (9.27e-2)"	"unprognostic (5.01e-3)"	"unprognostic (9.27e-2)"	"unprognostic (2.48e-1)"	"unprognostic (2.83e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.95e-2)"	"unprognostic (9.43e-2)"	"unprognostic (7.35e-2)"	"prognostic favorable (7.58e-9)"	"unprognostic (4.08e-2)"	"unprognostic (1.88e-1)"	"unprognostic (4.45e-3)"	"unprognostic (1.18e-1)"	108.7	98.9	22.7	42.1	23.7	54.0	49.0	27.1	29.1	36.3	35.6	109.0	81.8	45.3	21.2	94.1	34.3	48.5	264.1	23.1	29.5	153.3	112.8	39.3	50.1	27.1	27.4	30.0	49.2	136.7	27.8	43.1	26.6	45.7	99.3	35.0	50.2	50.3	295.0	38.9	71.9	67.7	24.9	38.4	80.5	31.3	25.7	43.2	64.2	357.0	67.5	66.1	32.7	23.4	171.4	134.5	74.8	127.9	104.6	91.4	88.4	96.5	80.8	110.6	86.2	159.5	95.5	165.9	159.6	103.0	177.7	110.9	150.2	135.8	166.1	111.1	88.4	116.9	175.6	116.7	80.3	194.7	116.0	104.8	97.6	116.4	63.4	72.3	134.0	137.0	298.5	119.7	121.8	188.1	161.8	138.9	87.4	206.0	98.2	113.1	117.8	225.9	151.8	250.8	92.3	99.9	156.3	262.1	143.9	149.9	100.5	165.8	87.9	120.7	97.3	238.1	149.4	89.3	187.1	114.6	115.0	204.1	130.2	132.7	63.9	136.0	46.9	81.6	49.4	37.8	46.8	46.8	87.2	38.5	47.9	50.5	39.9	68.1	116.9	29.9	49.0	64.2	22.7	23.7	27.1	29.1	23.1	29.5	27.1	27.4	26.6	24.9	25.7	23.4	26.7	28.9	20.7	14.7	26.3	31.4	42.7	124.7	31.3	47.1	24.0	19.2	356.2	51.5	70.5	79.1	22.9	110.2	27.3	56.1	226.9	69.3	10.2	27.6	26.2	32.2	30.6	53.9	23.9	55.9	62.7	36.3	36.7	28.0	26.6	35.3	26.0	86.8	69.2	21.9	25.3	44.1	114.0	41.0	26.5	7.3	23.3	37.5	37.4	15.9	62.2	36.0	38.1	21.1	16.7	42.6	51.4	42.2	30.7	24.3	60.0	178.9	55.5	45.5	26.3	28.4	44.8	55.2	51.5	48.0	32.4	108.4	29.5	73.7	78.7	39.2
FPGS		ENSG00000136877	"Folylpolyglutamate synthase"	Q05932	9	127794597-127814327	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	Ligase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050488	Approved				"Intracellular and membrane"	NA	NA			"Cluster 22: NK-cells - Unknown function"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 14: REH - Unknown function"	"Cluster 3: Monocytes - Immune response regulation"			"HPA050488: AB_2681143"	"unprognostic (6.37e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.02e-1)"	"prognostic favorable (9.08e-4)"	"unprognostic (1.25e-1)"	"unprognostic (2.67e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.89e-1)"	"unprognostic (6.25e-2)"	"unprognostic (2.63e-1)"	"unprognostic (1.16e-1)"	"unprognostic (6.97e-2)"	"unprognostic (1.76e-1)"	"unprognostic (8.54e-3)"	"unprognostic (2.61e-1)"	"unprognostic (1.58e-1)"	"unprognostic (1.55e-2)"	37.3	49.1	8.7	15.5	9.7	19.7	32.6	9.1	9.3	26.6	9.2	19.5	10.5	29.6	8.4	22.1	35.5	9.1	31.2	8.3	9.2	24.8	66.1	30.6	17.7	10.3	9.6	55.4	28.0	10.2	18.0	7.7	9.3	26.6	6.9	2.2	20.4	11.6	48.2	15.5	22.8	9.4	10.2	29.9	25.8	12.9	9.2	13.4	22.1	19.0	13.2	25.6	18.2	10.1	36.2	24.4	14.2	29.7	21.2	23.1	42.6	28.0	33.0	34.4	28.0	26.4	56.7	44.4	35.8	38.9	24.4	67.0	17.7	39.4	11.4	48.5	22.6	34.5	30.4	32.1	50.5	64.2	28.1	32.2	21.2	34.7	43.8	29.4	43.3	41.6	39.8	27.7	36.2	45.8	56.6	47.8	39.9	39.2	74.0	116.0	23.0	77.7	52.2	29.3	20.5	35.0	80.1	38.6	5.8	5.7	23.7	26.8	65.4	18.6	26.0	54.1	56.8	31.0	14.2	36.0	40.7	29.4	26.7	0.2	15.4	2.3	38.8	23.9	35.1	23.2	22.9	34.0	30.8	27.6	18.5	25.2	0.8	43.6	23.9	38.9	26.6	22.4	8.7	9.7	9.1	9.3	8.3	9.2	10.3	9.6	9.3	10.2	9.2	10.1	11.3	22.4	28.1	8.8	28.6	10.5	23.7	31.1	8.6	5.5	15.7	13.3	19.5	34.3	21.6	9.2	14.6	15.5	21.8	11.6	11.7	49.6	5.0	18.0	19.9	18.7	22.9	26.7	5.8	52.9	22.0	18.0	31.6	23.9	31.0	14.6	19.2	73.2	29.8	5.0	6.4	13.8	16.2	19.5	18.4	2.2	19.0	18.9	8.8	4.7	46.2	6.5	22.6	6.0	6.2	66.9	9.9	7.2	32.7	30.8	22.1	20.1	11.2	8.5	13.1	21.9	15.2	6.0	16.0	19.9	8.8	14.8	22.2	14.5	24.2	36.5
FTCD		ENSG00000160282	"Formimidoyltransferase cyclodeaminase"	O95954	21	46136262-46155579	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Histidine metabolism"	"Lyase, Multifunctional enzyme, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"liver: 939.8"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 131.5;Early spermatids: 104.7;Hepatocytes: 444.9;Late spermatids: 124.3;Proximal tubular cells: 395.1"	"Cancer enriched"	"Detected in some"	8	"liver cancer: 87.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	30	"Hep G2: 92.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA020073, HPA030928, HPA030929, HPA036114"	Enhanced		Approved	"Plasma membrane,Cytosol"		No	NA		1600000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol	"Plasma membrane"	"HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947"	"unprognostic (1.71e-1)"	"unprognostic (2.27e-1)"	"unprognostic (4.62e-5)"	"unprognostic (2.90e-2)"	"unprognostic (1.13e-1)"	"unprognostic (2.96e-1)"	"prognostic favorable (1.70e-4)"	"unprognostic (1.85e-1)"	"unprognostic (2.67e-1)"	"unprognostic (1.99e-1)"	"prognostic favorable (6.78e-5)"	"unprognostic (1.80e-1)"	"prognostic favorable (5.78e-4)"	"unprognostic (3.80e-2)"	"unprognostic (3.60e-1)"	"unprognostic (9.37e-2)"	"unprognostic (2.10e-1)"	0.4	1.7	5.4	0.2	6.8	0.0	0.4	3.6	8.4	1.3	3.0	1.3	1.3	1.2	0.4	0.3	0.9	0.1	1.6	4.9	4.7	155.7	939.8	0.2	0.2	4.6	3.9	3.0	4.0	0.0	3.4	0.0	5.6	4.2	0.0	0.0	0.2	0.6	0.4	0.3	1.7	0.0	3.5	0.5	0.5	13.9	4.4	0.0	0.9	0.0	0.0	1.3	1.0	5.5	0.0	0.0	0.0	0.0	0.4	0.0	0.1	0.0	0.0	0.1	0.0	3.1	0.0	0.3	0.2	0.0	0.7	0.0	0.0	0.0	0.0	0.1	0.6	0.6	0.0	92.9	0.0	0.6	0.3	0.1	0.0	0.2	0.0	0.0	0.0	0.2	0.7	0.0	0.0	0.7	0.0	0.0	1.9	0.0	0.1	0.2	0.2	0.0	0.2	0.0	0.9	0.3	0.0	0.1	0.1	0.1	0.1	0.0	0.0	0.3	0.4	0.5	0.0	0.3	0.1	0.0	0.4	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	5.4	6.8	3.6	8.4	4.9	4.7	4.6	3.9	5.6	3.5	4.4	5.5	0.0	0.0	0.0	1.0	8.1	0.1	0.0	0.0	0.0	1.3	0.2	0.5	1.5	131.5	0.0	9.2	0.0	0.0	0.1	0.0	46.9	0.0	104.7	0.1	0.4	1.8	0.0	61.5	10.5	0.0	0.0	0.6	0.0	0.2	0.0	0.6	30.4	444.9	0.1	3.3	5.9	0.1	0.0	28.9	0.0	124.3	3.1	1.6	0.0	1.0	0.0	0.2	0.0	1.0	18.5	0.0	0.1	2.6	0.0	0.5	0.3	395.1	0.0	0.4	0.0	0.2	0.5	39.2	17.9	0.2	0.4	0.0	3.6	0.1	0.2	0.1
GCSH		ENSG00000140905	"Glycine cleavage system protein H"	P23434	16	81081945-81096395	"Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"HPA041368, HPA057079"	Supported		Approved	Vesicles	"Intracellular and membrane"	NA	NA		50000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Vesicles		"HPA041368: AB_10804001, HPA057079: "	"unprognostic (4.09e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.47e-3)"	"unprognostic (2.55e-3)"	"unprognostic (4.87e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.75e-1)"	"unprognostic (1.96e-2)"	"unprognostic (6.92e-2)"	"unprognostic (2.80e-2)"	"prognostic favorable (6.26e-6)"	"unprognostic (1.12e-2)"	"unprognostic (2.59e-1)"	"unprognostic (6.31e-2)"	"unprognostic (6.47e-2)"	28.7	20.1	58.9	6.9	66.5	6.3	24.2	62.9	113.8	18.2	50.8	16.0	7.2	17.5	68.9	15.5	19.8	11.7	38.1	55.8	60.9	78.2	118.9	10.8	6.7	60.1	66.0	18.4	19.7	31.0	14.3	26.0	61.1	18.7	13.0	15.6	15.6	16.7	59.3	10.1	9.5	11.8	61.7	6.3	17.5	7.4	63.7	10.4	96.4	63.6	9.3	18.3	15.2	67.8	63.6	28.3	82.4	37.0	40.4	30.9	175.5	35.9	26.4	43.3	20.6	37.0	57.2	17.2	32.3	15.9	31.9	33.3	64.5	36.5	71.6	4.7	86.7	21.8	34.9	114.6	45.7	70.3	24.1	32.0	47.8	26.8	53.7	13.0	22.3	45.1	86.3	3.4	42.9	67.7	45.9	138.8	113.0	49.6	57.5	72.7	44.1	25.5	98.4	56.4	43.7	45.3	53.3	32.9	70.8	63.9	48.3	33.2	19.8	27.6	49.3	44.0	37.8	14.7	31.8	102.1	18.2	41.3	22.6	3.6	1.3	1.3	2.8	2.1	4.6	3.5	2.6	4.0	3.9	2.5	4.4	5.9	1.7	7.0	1.7	10.8	2.2	2.4	58.9	66.5	62.9	113.8	55.8	60.9	60.1	66.0	61.1	61.7	63.7	67.8	31.1	3.2	5.9	16.3	24.8	29.1	94.6	73.6	52.3	43.7	97.9	115.6	12.9	44.3	31.4	80.9	37.5	553.4	13.8	15.3	295.4	70.0	32.4	34.8	128.3	31.9	26.4	71.1	12.6	42.5	1476.4	61.6	31.1	55.2	36.3	38.5	33.2	352.0	118.8	38.7	11.9	34.3	67.1	19.7	34.6	19.5	140.8	18.8	85.4	4.7	17.7	215.8	19.6	19.6	35.2	42.3	17.8	141.1	51.7	123.9	13.7	655.9	20.0	45.7	32.9	46.2	50.2	20.7	77.3	78.4	27.1	228.8	16.3	114.5	49.4	69.8
GGH		ENSG00000137563	"Gamma-glutamyl hydrolase"	Q92820	8	63014881-63039407	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 125.7;liver: 188.6"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	5	"plasmacytoid DC: 30.6"	"Lineage enriched"	"Detected in all"	5	"dendritic cells: 30.6"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019296, HPA025226"	Approved				"Intracellular and membrane"	NA	NA		1200000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"			"CAB019296: , HPA025226: AB_1849645"	"unprognostic (9.29e-2)"	"unprognostic (1.22e-1)"	"unprognostic (5.48e-3)"	"prognostic unfavorable (3.99e-7)"	"unprognostic (5.57e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (1.65e-4)"	"unprognostic (1.95e-2)"	"unprognostic (1.60e-1)"	"unprognostic (2.11e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.69e-2)"	"unprognostic (9.62e-3)"	"unprognostic (1.50e-1)"	"unprognostic (2.36e-1)"	"unprognostic (6.50e-2)"	9.8	5.4	11.1	14.2	11.1	43.7	16.5	10.7	14.3	5.9	13.1	54.3	11.3	6.3	4.4	20.7	3.5	4.3	3.1	11.1	12.3	125.7	188.6	8.0	10.9	13.3	11.1	3.1	9.9	13.1	1.9	54.9	13.7	4.4	74.4	2.1	13.0	3.7	2.1	27.2	9.9	11.6	10.1	5.5	8.2	33.9	14.4	17.8	2.4	3.2	22.5	8.5	10.8	11.1	110.5	97.6	97.4	15.7	94.1	39.6	69.6	64.3	105.1	94.2	137.7	144.5	183.8	69.8	18.0	77.1	166.8	87.2	97.2	101.9	138.9	139.0	71.6	112.3	50.3	105.1	17.6	53.5	65.9	29.1	29.2	93.9	50.7	59.4	116.1	66.9	62.4	255.2	177.3	64.3	28.8	71.1	51.0	231.6	86.0	77.6	95.2	98.1	75.8	40.3	38.6	69.9	91.8	103.6	98.5	91.6	116.6	65.8	65.5	104.2	115.6	99.4	111.3	112.6	127.2	88.3	158.0	0.1	185.0	0.0	2.1	2.3	1.1	1.7	0.8	6.5	1.5	1.7	0.9	2.7	1.8	1.9	3.0	4.4	2.0	30.6	2.7	1.9	11.1	11.1	10.7	14.3	11.1	12.3	13.3	11.1	13.7	10.1	14.4	11.1	13.1	16.0	7.3	11.1	26.1	30.2	23.2	66.6	9.1	2.0	14.9	21.0	3.2	17.2	31.1	22.0	0.0	510.3	11.7	49.2	37.2	19.7	471.0	5.4	11.5	13.1	13.2	62.5	11.5	7.4	273.4	27.2	11.7	7.6	10.8	21.4	13.6	219.5	72.4	0.0	8.7	70.7	44.7	21.0	15.5	154.2	5.9	12.0	24.9	1.0	32.1	23.1	2.1	3.5	2.9	4.3	23.7	8.2	106.9	10.5	4.3	340.8	18.3	1.3	26.3	12.8	20.4	80.3	133.0	35.9	43.0	754.5	8.5	9.3	102.0	23.1
GLDC	"GCSP, NKH"	ENSG00000178445	"Glycine decarboxylase"	P23378	9	6532467-6645729	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"liver: 173.5"	"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0"	"Cancer enhanced"	"Detected in many"		"testis cancer: 41.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002318, HPA052887"	Enhanced		Supported	Nucleoplasm,Mitochondria		NA	NA		740000	"Cluster 37: B-cells - Transcription"	"Cluster 15: Liver - Metabolism"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria	Nucleoplasm	"HPA002318: AB_1849700, HPA052887: AB_2681980"	"unprognostic (6.73e-2)"	"unprognostic (1.19e-1)"	"unprognostic (6.50e-2)"	"prognostic unfavorable (5.24e-5)"	"unprognostic (1.50e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.40e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.47e-2)"	"unprognostic (2.69e-1)"	"prognostic favorable (3.50e-4)"	"unprognostic (1.65e-2)"	"unprognostic (1.27e-1)"	"unprognostic (5.62e-3)"	"unprognostic (1.17e-2)"	0.3	0.3	15.3	1.4	15.5	0.5	0.8	14.7	23.7	0.4	12.9	1.0	0.8	0.4	5.2	3.2	0.7	0.8	0.1	14.8	14.4	38.2	173.5	1.0	1.6	14.0	13.6	0.3	0.1	0.0	4.9	15.2	13.4	0.5	0.4	1.6	1.1	1.0	1.3	4.5	0.8	0.0	13.1	1.2	1.0	3.5	15.8	0.0	5.1	0.1	1.2	1.1	0.1	15.3	0.6	4.9	2.1	25.6	0.2	0.4	235.7	0.1	0.0	0.0	0.1	58.2	0.5	0.3	5.6	0.1	0.7	0.4	0.0	0.7	0.2	1.2	13.4	0.2	0.3	38.3	0.0	0.1	45.6	0.0	0.1	1.8	0.3	1.0	9.0	4.3	0.0	0.5	1.2	1.5	0.9	0.2	27.5	4.6	3.8	1.3	0.0	0.5	95.4	1.0	22.6	11.7	0.0	21.4	0.3	13.9	5.3	0.1	3.0	0.6	0.6	2.6	1.3	1.1	34.4	0.1	0.8	2.4	5.1	0.4	0.1	0.1	0.1	0.0	0.1	0.8	0.1	0.0	0.0	0.1	0.0	0.1	0.4	0.1	0.1	0.1	0.0	0.3	15.3	15.5	14.7	23.7	14.8	14.4	14.0	13.6	13.4	13.1	15.8	15.3	0.2	0.0	0.0	17.6	1.9	0.0	0.0	0.2	1.2	0.4	1.5	0.6	0.7	11.5	0.1	31.3	0.0	79.0	0.2	0.0	5.9	0.0	12.6	5.4	0.5	0.6	0.0	0.0	21.6	0.2	41.6	0.3	0.0	10.7	0.0	1.1	2.2	120.5	7.0	0.0	15.9	0.0	0.0	2.8	0.3	10.8	0.3	0.4	0.0	1.9	0.0	9.6	0.0	52.3	1.8	0.1	0.0	0.0	15.1	0.0	0.0	31.6	0.0	0.4	0.0	1.7	0.8	4.5	5.1	0.4	0.0	46.0	0.8	0.0	0.0	0.1
GPHN	KIAA1385	ENSG00000171723	Gephyrin	Q9NQX3	14	66507407-67181803	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Molybdenum cofactor biosynthesis"	"Multifunctional enzyme, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 62.4"	"Group enriched"	"Detected in many"	4	"Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003116, CAB004419, HPA024694"	Enhanced		Approved	Vesicles,Cytosol		NA	NA		6900	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Vesicles	Cytosol	"CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616"	"unprognostic (8.37e-2)"	"unprognostic (2.53e-2)"	"unprognostic (2.42e-1)"	"unprognostic (1.20e-1)"	"unprognostic (5.14e-2)"	"unprognostic (4.89e-3)"	"unprognostic (8.29e-2)"	"unprognostic (1.41e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.23e-1)"	"unprognostic (2.49e-2)"	"unprognostic (8.54e-2)"	"prognostic favorable (5.25e-12)"	"unprognostic (9.81e-2)"	"unprognostic (2.27e-1)"	"unprognostic (7.50e-2)"	"prognostic unfavorable (4.61e-5)"	13.8	11.1	35.5	3.5	36.0	2.6	13.4	48.4	54.1	9.7	20.9	11.8	7.4	9.9	11.6	12.2	11.1	6.2	17.1	36.1	37.6	25.3	62.4	9.3	3.8	32.7	35.3	8.9	23.9	11.7	13.6	3.6	32.3	11.3	10.1	23.1	9.4	6.6	24.5	15.2	9.0	6.2	32.4	6.7	14.7	6.2	34.6	5.8	11.9	13.8	4.3	11.4	10.7	39.5	39.9	8.8	13.7	15.9	14.2	17.5	9.5	11.1	5.7	12.7	12.2	2.8	17.9	0.0	1.8	7.7	5.5	13.1	17.0	19.9	18.9	15.0	14.9	15.8	9.4	22.3	7.8	9.1	15.8	13.3	13.8	2.9	16.0	4.8	11.8	13.8	9.3	14.2	7.1	19.2	11.9	22.2	5.0	28.3	17.0	0.0	32.5	13.2	16.7	7.5	25.8	10.3	10.2	31.6	12.4	3.3	18.5	11.5	6.7	14.1	24.8	11.3	13.0	22.8	9.1	0.3	10.5	0.8	11.2	0.0	0.7	0.3	2.0	1.2	3.2	1.2	2.5	1.7	1.1	1.9	1.7	1.6	0.0	1.3	1.0	1.5	3.0	0.7	35.5	36.0	48.4	54.1	36.1	37.6	32.7	35.3	32.3	32.4	34.6	39.5	11.5	6.4	13.1	493.0	11.8	4.7	9.2	5.8	27.9	34.3	12.4	6.7	12.7	8.6	10.8	1.8	52.1	3.9	3.5	8.6	13.7	4.0	3.8	7.2	13.5	10.7	6.0	7.6	686.5	5.3	2.3	8.7	19.9	13.6	0.0	3.9	15.7	47.6	3.7	43.7	866.7	15.0	8.2	5.8	1.7	5.0	11.1	4.5	1.8	148.0	1.3	8.9	1.0	576.1	597.5	3.1	7.8	5.7	15.1	11.5	7.1	20.1	2.4	34.9	0.0	12.5	11.8	11.8	8.9	26.7	5.8	2.1	7.9	9.0	10.4	6.5
MOCS1	MOCOD	ENSG00000124615	"Molybdenum cofactor synthesis 1"	Q9NZB8	6	39899578-39934551	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Molybdenum cofactor biosynthesis"	Lyase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 33.7;Hepatocytes: 36.2;Sertoli cells: 78.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"CACO-2: 40.4;JURKAT: 51.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA045783, HPA058177, HPA075505"	Uncertain		Enhanced	Cytosol		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 15: Liver - Metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 47: Cytotrophoblasts - Unknown function"	Cytosol		"HPA045783: AB_10960058, HPA058177: AB_2683629, HPA075505: AB_2686751"	"unprognostic (1.22e-1)"	"prognostic unfavorable (1.07e-5)"	"unprognostic (3.26e-2)"	"unprognostic (1.44e-1)"	"unprognostic (9.03e-2)"	"unprognostic (1.99e-1)"	"unprognostic (2.61e-2)"	"unprognostic (4.85e-2)"	"unprognostic (3.14e-2)"	"unprognostic (1.08e-1)"	"prognostic favorable (6.07e-5)"	"unprognostic (5.34e-3)"	"unprognostic (1.21e-1)"	"unprognostic (3.97e-3)"	"unprognostic (2.78e-1)"	"unprognostic (2.93e-1)"	"unprognostic (6.21e-2)"	33.7	9.5	14.6	3.2	17.9	0.0	26.8	16.8	14.7	8.8	11.2	11.7	16.2	10.0	10.1	6.7	10.3	5.5	22.0	12.7	16.0	20.4	40.3	22.9	4.5	17.4	18.8	9.0	11.9	9.6	5.3	35.6	16.2	5.3	5.6	3.0	6.1	7.5	25.7	7.3	12.7	9.2	15.6	2.6	7.6	3.2	17.3	3.3	16.0	45.0	3.4	10.0	6.6	16.4	0.0	2.1	7.0	11.4	19.3	7.2	15.2	8.7	15.0	12.1	10.0	40.4	0.1	0.0	8.4	7.4	7.0	0.4	8.2	9.8	8.7	0.0	8.6	0.0	0.0	13.7	12.2	0.0	3.1	12.0	3.7	7.9	4.2	7.2	10.1	51.1	8.4	0.7	11.7	5.0	16.0	0.0	7.9	0.1	4.6	0.0	6.3	1.1	7.6	8.2	6.1	8.5	0.0	4.2	7.0	6.3	5.2	1.4	16.2	12.2	9.8	7.7	4.1	0.0	1.7	0.0	1.3	0.0	4.3	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.6	0.5	0.0	0.3	0.0	0.0	0.0	0.2	14.6	17.9	16.8	14.7	12.7	16.0	17.4	18.8	16.2	15.6	17.3	16.4	5.7	6.4	1.5	6.2	0.1	0.6	0.6	0.7	1.2	1.6	9.3	6.5	11.6	8.6	0.3	9.2	12.5	33.7	0.5	3.6	5.9	4.4	0.8	0.9	1.6	3.3	0.0	0.0	3.2	4.1	2.3	4.3	1.1	1.4	1.3	6.3	3.3	36.2	2.9	3.3	2.6	3.5	0.0	2.8	1.0	1.8	3.7	0.4	1.8	2.8	0.0	4.6	0.0	1.0	4.4	1.0	9.1	3.0	1.3	0.2	13.2	17.8	0.0	2.2	78.9	3.9	20.3	1.6	1.9	1.2	1.1	6.2	0.3	0.8	5.5	0.6
MOCS2	"MOCO1, MOCS2A, MOCS2B"	ENSG00000164172	"Molybdenum cofactor synthesis 2"	"O96007, O96033"	5	53095679-53110063	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Molybdenum cofactor biosynthesis"	Transferase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 573.2;Proximal tubular cells: 281.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037679, HPA037680"	Approved		Supported	"Nucleoplasm,Nuclear speckles,Cytosol"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	"Nucleoplasm, Nuclear speckles"	"HPA037679: AB_2675604, HPA037680: AB_10673635"	"unprognostic (3.27e-1)"	"unprognostic (3.11e-2)"	"unprognostic (2.82e-1)"	"unprognostic (8.37e-3)"	"unprognostic (2.12e-1)"	"unprognostic (3.48e-2)"	"unprognostic (1.60e-2)"	"unprognostic (1.33e-1)"	"unprognostic (6.66e-2)"	"unprognostic (7.59e-2)"	"unprognostic (2.41e-3)"	"unprognostic (1.85e-1)"	"prognostic favorable (3.68e-6)"	"unprognostic (1.04e-1)"	"unprognostic (1.04e-2)"	"unprognostic (2.04e-1)"	"unprognostic (5.86e-2)"	48.7	79.4	79.1	24.9	84.9	9.1	42.1	80.3	107.6	34.7	74.4	41.9	40.8	30.0	45.9	35.2	26.5	31.3	87.0	84.3	86.3	114.8	126.2	28.2	26.1	79.2	80.5	43.5	42.4	89.6	30.5	35.9	82.4	36.8	32.3	59.3	48.9	44.9	109.3	16.6	40.2	34.4	85.6	23.6	37.2	26.0	88.0	28.3	55.4	111.8	25.2	30.8	24.6	87.4	79.4	62.7	42.9	109.9	85.0	83.2	51.6	99.5	91.9	74.4	89.8	79.7	56.5	76.7	143.5	69.9	127.1	45.0	91.7	96.7	117.2	19.6	84.8	61.7	58.2	75.9	94.4	65.0	43.0	65.1	41.7	91.7	83.5	81.0	85.1	101.4	58.7	44.2	129.5	115.5	72.7	31.8	37.0	34.2	130.1	36.0	93.0	67.0	144.1	56.6	29.4	33.7	69.4	57.3	72.9	56.9	107.2	15.4	55.6	76.9	81.0	69.1	120.5	49.4	84.8	91.5	106.7	16.8	125.1	14.5	21.8	15.6	36.9	26.9	46.2	37.5	42.7	42.8	29.8	40.5	55.3	49.2	3.8	43.5	25.4	27.8	44.9	28.9	79.1	84.9	80.3	107.6	84.3	86.3	79.2	80.5	82.4	85.6	88.0	87.4	51.7	54.5	29.7	14.4	23.5	13.4	40.1	48.5	19.9	30.2	55.7	50.5	122.9	62.9	37.9	69.9	27.1	95.4	19.4	18.2	573.2	43.7	7.3	22.6	29.0	37.6	26.4	18.7	19.1	43.7	37.3	55.7	19.9	26.8	10.1	38.8	26.0	132.6	41.3	6.7	18.4	22.7	44.7	31.2	20.1	14.6	50.7	28.7	23.2	6.5	12.2	67.5	29.9	4.5	11.9	22.1	18.2	68.8	26.7	34.5	65.7	281.7	32.9	21.7	32.9	73.8	49.4	46.7	62.9	37.5	15.6	32.3	25.8	64.2	30.9	34.5
MTHFD1	"MTHFC, MTHFD"	ENSG00000100714	"Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1"		14	64388031-64463457	"Human disease related genes, Metabolic proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"			"Tissue enriched"	"Detected in all"	6	"liver: 356.9"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 142.9;Proximal tubular cells: 75.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000704, HPA001290, HPA015006, HPA050052"	Approved		Enhanced	Cytosol		NA	Yes			"Cluster 43: B-cells - Humoral immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol		"HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998"	"unprognostic (3.58e-2)"	"unprognostic (5.50e-3)"	"unprognostic (1.24e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.37e-1)"	"unprognostic (7.01e-2)"	"unprognostic (8.85e-3)"	"unprognostic (7.62e-3)"	"unprognostic (1.28e-1)"	"unprognostic (2.29e-2)"	"prognostic unfavorable (6.96e-4)"	"unprognostic (1.84e-1)"	"prognostic favorable (5.93e-5)"	"unprognostic (2.45e-2)"	"unprognostic (1.75e-1)"	"unprognostic (7.30e-2)"	"unprognostic (2.29e-2)"	56.4	18.0	8.6	20.0	17.4	27.0	29.8	8.3	12.3	16.9	15.0	23.3	19.7	16.1	9.9	25.1	16.0	13.1	28.1	12.9	8.1	55.3	356.9	15.4	23.6	7.5	7.8	24.9	23.8	27.5	9.2	13.3	7.0	12.9	27.5	3.6	15.6	13.8	64.1	17.1	18.9	20.0	7.2	14.5	17.9	4.7	8.9	30.2	20.5	61.9	27.7	18.6	16.6	8.3	294.1	164.9	58.5	143.6	70.5	53.4	95.7	106.4	83.3	148.1	147.4	161.2	144.2	103.3	49.6	67.1	68.3	146.0	177.6	111.2	160.4	107.3	117.9	122.2	143.5	131.8	50.6	104.5	81.2	43.0	37.3	124.3	66.4	57.5	93.1	98.1	108.5	98.7	114.7	270.1	179.9	62.3	118.0	186.5	160.4	138.3	201.2	114.4	110.5	160.9	128.7	49.0	183.7	111.4	58.3	54.0	164.4	58.6	51.5	115.1	184.1	102.2	134.2	58.8	65.6	177.9	107.4	125.2	134.8	0.4	11.7	0.1	9.7	19.5	13.0	27.0	10.1	12.3	17.7	15.3	7.8	10.7	0.9	17.8	16.7	4.0	19.5	12.2	8.6	17.4	8.3	12.3	12.9	8.1	7.5	7.8	7.0	7.2	8.9	8.3	8.1	19.2	23.5	15.0	16.2	13.8	14.2	14.7	13.6	0.0	9.8	8.1	43.9	15.7	19.5	16.5	0.0	30.6	10.8	7.9	41.1	16.9	1.4	6.8	11.7	12.3	3.0	42.3	19.5	10.3	30.9	14.9	15.3	8.7	50.7	27.2	12.8	142.9	25.3	0.0	15.6	14.3	2.0	13.0	11.0	1.5	13.1	12.3	14.2	8.4	13.3	0.0	8.2	14.1	10.9	11.7	6.3	13.2	24.1	10.2	8.2	75.3	11.5	0.0	19.7	13.1	19.3	0.9	8.9	19.5	10.7	9.9	16.6	21.4	24.6	12.7
MTHFD1L	"DKFZP586G1517, FLJ21145, FTHFSDC1"	ENSG00000120254	"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"	Q6UB35	6	150865679-151101887	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"One-carbon metabolism"	Ligase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 84.0;Extravillous trophoblasts: 166.5;Granulosa cells: 86.9;Microglial cells: 126.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Group enriched"	"Detected in many"	4	"dendritic cells: 1.1;T-cells: 1.8"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015006, HPA029040, HPA029041, HPA050052, HPA074911"	Approved		Enhanced	Mitochondria		NA	NA		89000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 21: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Mitochondria		"HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723"	"unprognostic (3.66e-2)"	"prognostic unfavorable (1.68e-5)"	"unprognostic (1.02e-1)"	"prognostic unfavorable (7.28e-4)"	"unprognostic (3.25e-1)"	"prognostic unfavorable (5.10e-4)"	"prognostic unfavorable (8.33e-5)"	"unprognostic (6.35e-3)"	"unprognostic (2.45e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.11e-2)"	"unprognostic (2.93e-2)"	"unprognostic (3.51e-1)"	"unprognostic (2.91e-1)"	"prognostic unfavorable (8.69e-5)"	12.5	12.2	7.1	11.4	6.7	13.2	7.9	25.1	7.4	7.1	8.3	7.4	3.2	8.4	6.2	6.7	7.1	5.9	11.5	6.4	9.8	12.7	5.6	19.5	11.1	11.5	10.1	14.6	10.7	6.8	9.2	14.3	11.0	5.5	7.9	7.5	3.2	7.0	1.3	6.0	5.2	10.0	11.6	9.2	6.0	9.9	8.4	8.6	10.9	0.5	10.8	12.8	4.2	15.4	40.6	35.1	44.9	110.0	11.5	40.0	108.4	63.0	68.3	62.1	75.7	71.8	37.4	152.3	41.1	96.9	36.8	42.7	72.4	61.8	76.8	63.4	65.3	62.7	60.4	66.1	72.4	115.7	9.8	47.7	76.9	60.6	109.8	55.5	105.5	81.6	150.9	76.2	65.0	86.1	57.1	23.9	45.5	40.7	32.1	67.2	33.2	67.1	42.1	19.6	44.1	32.5	83.9	36.7	53.0	40.6	11.5	79.5	80.6	41.4	90.6	91.9	90.5	62.3	63.5	154.0	68.8	105.7	54.0	0.0	0.2	0.0	0.2	0.3	0.4	0.2	0.6	0.7	1.1	0.3	0.5	0.6	0.0	0.3	0.3	0.5	1.8	0.2	7.1	6.7	25.1	7.4	6.4	9.8	11.5	10.1	11.0	11.6	8.4	15.4	6.9	0.0	1.7	47.7	6.9	6.5	8.0	15.7	1.8	0.0	3.3	4.1	2.4	1.5	9.8	14.7	0.0	25.8	1.4	2.6	7.9	9.0	44.9	11.3	18.4	10.7	1.2	5.0	84.0	18.1	166.5	14.4	8.2	22.2	0.0	86.9	6.1	1.7	24.9	0.0	73.8	3.0	46.8	3.0	13.3	6.2	0.6	13.8	35.6	126.5	2.4	0.0	2.1	60.8	59.3	19.2	1.4	7.9	14.0	31.3	0.9	15.2	5.3	0.0	0.0	8.7	13.1	0.5	6.8	2.3	3.4	73.6	4.0	42.9	4.0	35.1
MTHFD2		ENSG00000065911	"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase"	P13995	2	74186172-74217565	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"One-carbon metabolism"	"Hydrolase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Langerhans cells: 243.6;monocytes: 184.1;Smooth muscle cells: 239.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003684, HPA049657"	Approved		Supported	Mitochondria	"Intracellular and membrane"	NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 52: Non-specific - Ribosome"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 48: Smooth muscle cells - ECM organization"	Mitochondria		"CAB003684: AB_425867, HPA049657: AB_2680842"	"unprognostic (1.82e-3)"	"unprognostic (4.60e-2)"	"unprognostic (8.12e-2)"	"prognostic unfavorable (2.07e-5)"	"prognostic favorable (1.01e-4)"	"unprognostic (3.10e-3)"	"unprognostic (2.24e-3)"	"unprognostic (4.75e-3)"	"unprognostic (2.64e-2)"	"unprognostic (3.96e-2)"	"unprognostic (3.76e-3)"	"unprognostic (3.57e-3)"	"prognostic unfavorable (1.11e-16)"	"unprognostic (3.66e-2)"	"unprognostic (6.52e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.34e-3)"	40.0	12.3	11.2	54.5	13.0	25.8	34.8	12.7	14.7	28.5	11.2	30.6	18.6	21.5	14.5	23.0	34.2	20.1	19.6	10.0	16.6	19.6	7.3	23.0	45.6	16.6	15.8	11.7	65.9	9.8	18.0	17.7	17.1	16.3	33.7	2.9	17.7	16.7	36.7	11.8	16.0	27.3	14.8	19.0	36.1	17.7	13.1	28.5	18.5	55.3	57.8	48.0	20.5	15.7	197.4	107.8	89.2	235.6	90.0	113.9	186.1	286.2	185.2	156.2	216.7	242.8	81.8	391.0	65.4	154.2	167.5	70.7	296.7	142.0	314.9	248.9	100.9	424.6	55.4	181.9	319.8	360.1	234.8	202.9	423.4	188.5	794.4	74.8	99.0	636.5	192.2	548.0	157.5	159.6	209.5	261.0	161.1	293.3	95.8	222.6	266.3	339.4	72.0	80.8	198.2	143.8	97.4	238.3	549.7	56.9	208.5	324.4	52.9	39.1	359.9	97.7	286.5	484.5	257.6	379.2	111.4	304.1	132.5	43.9	24.0	31.1	8.5	56.6	13.0	13.4	15.2	10.1	34.9	12.2	11.5	7.9	3.2	29.3	57.0	13.0	36.8	22.0	11.2	13.0	12.7	14.7	10.0	16.6	16.6	15.8	17.1	14.8	13.1	15.7	19.7	16.0	20.2	0.3	49.7	89.3	58.8	54.1	27.3	0.0	53.2	38.0	11.5	4.3	28.2	1.8	0.0	31.5	48.2	19.9	3.9	55.7	3.9	9.7	104.7	35.1	19.1	104.1	1.0	107.9	56.9	45.6	68.8	21.7	53.3	8.7	19.2	0.8	66.2	0.0	3.7	64.0	38.7	61.6	243.6	3.8	22.7	100.6	71.2	12.2	184.1	0.0	27.8	6.6	1.1	81.2	7.5	21.1	141.2	95.7	3.3	3.3	8.5	0.0	138.1	126.3	239.0	36.5	54.9	42.0	74.6	14.0	71.4	21.6	34.0	64.2
MTHFD2L	MGC72244	ENSG00000163738	"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like"	Q9H903	4	74114174-74303099	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Amino-acid biosynthesis, Histidine biosynthesis, Methionine biosynthesis, One-carbon metabolism, Purine biosynthesis"	"Hydrolase, Multifunctional enzyme, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035434	Uncertain					NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 30: Mammary glandular cells - Lactation"			"HPA035434: AB_10601038"	"unprognostic (2.01e-1)"	"unprognostic (2.19e-1)"	"unprognostic (2.03e-1)"	"unprognostic (2.32e-2)"	"unprognostic (1.52e-2)"	"unprognostic (4.09e-2)"	"unprognostic (2.67e-2)"	"unprognostic (7.73e-3)"	"unprognostic (1.42e-4)"	"unprognostic (3.45e-3)"	"unprognostic (4.23e-2)"	"unprognostic (5.07e-2)"	"unprognostic (1.44e-1)"	"unprognostic (3.16e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.00e-1)"	"unprognostic (1.81e-3)"	1.6	3.7	5.6	1.2	5.4	1.7	3.3	3.5	6.5	1.4	1.1	1.6	1.6	1.6	3.4	1.9	1.5	1.1	6.0	4.1	8.5	1.9	7.0	1.3	1.2	5.0	5.0	1.6	1.6	2.5	1.5	1.7	5.1	1.5	1.1	2.6	1.4	1.7	2.7	1.2	1.0	1.2	5.4	1.4	1.4	0.9	5.8	3.4	2.0	3.9	1.1	1.3	1.2	7.6	2.8	2.8	4.0	3.6	1.4	2.1	0.9	3.3	2.6	2.2	2.4	2.2	2.6	3.0	4.5	1.5	1.6	1.7	3.2	2.2	3.3	3.1	2.0	3.7	1.9	2.6	2.4	5.8	0.7	1.5	5.1	3.3	7.9	4.1	4.7	6.7	6.6	3.6	2.7	2.7	10.9	8.3	1.2	4.5	3.1	10.9	2.7	5.1	14.2	1.4	3.7	8.0	1.8	2.8	3.5	4.3	1.5	4.0	4.9	2.5	3.8	4.8	5.6	3.6	5.0	8.8	15.5	1.3	3.8	0.3	0.9	0.4	0.3	0.9	0.3	1.8	0.2	0.4	1.5	0.6	0.8	0.9	0.6	1.1	3.5	1.6	1.4	1.0	5.6	5.4	3.5	6.5	4.1	8.5	5.0	5.0	5.1	5.4	5.8	7.6	23.3	22.4	19.6	57.5	18.9	16.6	63.5	31.1	30.1	0.0	90.5	53.6	24.5	30.0	27.6	49.7	0.0	17.9	17.1	23.3	84.1	24.0	85.7	67.1	11.0	19.9	37.2	44.2	41.2	19.1	8.8	13.5	35.7	50.4	10.2	35.5	25.0	104.7	24.5	0.0	41.0	34.7	69.2	27.3	23.0	23.2	12.8	30.4	16.0	20.6	17.3	0.0	12.3	74.9	73.1	15.6	19.4	8.6	20.9	69.2	18.3	51.3	30.1	0.0	26.3	19.4	21.1	8.1	12.3	44.0	22.6	12.3	11.1	36.8	36.4	71.9
MTHFR		ENSG00000177000	"Methylenetetrahydrofolate reductase"	P42898	1	11785723-11806455	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Allosteric enzyme, Oxidoreductase"	"Disease variant, Schizophrenia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"K-562: 44.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA063389, HPA076180, HPA077255"	Enhanced		Approved	"Cell Junctions"		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 68: Epididymis - Unknown function"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 44: Endometrium - Transcription"	"Cell Junctions"		"HPA063389: AB_2685001, HPA076180: , HPA077255: "	"unprognostic (3.25e-2)"	"unprognostic (8.19e-2)"	"unprognostic (4.48e-2)"	"unprognostic (2.11e-2)"	"unprognostic (1.34e-1)"	"prognostic favorable (3.97e-5)"	"prognostic unfavorable (1.19e-4)"	"unprognostic (1.75e-2)"	"unprognostic (2.85e-1)"	"unprognostic (8.69e-2)"	"prognostic favorable (4.81e-5)"	"unprognostic (3.10e-1)"	"prognostic favorable (2.12e-4)"	"unprognostic (2.35e-3)"	"unprognostic (2.94e-1)"	"unprognostic (4.14e-2)"	"unprognostic (1.80e-2)"	12.3	11.3	7.1	10.8	10.3	28.9	10.2	12.8	8.8	9.0	5.0	11.1	10.8	8.9	53.5	10.3	12.3	10.1	23.9	10.4	6.2	12.8	13.1	16.8	12.3	9.9	7.0	19.7	11.4	6.6	17.7	7.1	9.4	10.2	8.7	12.6	6.8	6.7	17.9	13.4	14.7	10.8	5.1	18.3	14.6	10.9	8.0	7.9	16.3	16.8	12.2	10.3	7.9	8.9	2.2	9.4	10.9	12.3	10.2	15.1	2.0	5.2	14.6	6.0	5.1	8.1	13.2	18.0	3.6	7.5	16.3	4.1	8.1	7.7	2.4	9.3	6.8	13.4	13.3	3.2	13.7	7.4	16.4	13.6	6.1	8.0	6.4	10.0	10.7	17.2	44.1	11.0	6.7	3.3	8.2	3.5	3.6	9.5	3.0	8.9	6.0	20.3	8.8	11.7	10.5	17.6	8.1	7.8	10.9	6.2	12.9	11.7	8.5	6.0	4.9	7.2	1.6	6.4	9.4	32.8	7.6	16.8	5.6	0.7	2.3	1.1	2.7	4.3	0.9	1.6	0.8	1.4	1.7	2.3	1.2	1.4	2.5	2.0	6.1	0.9	0.6	1.6	7.1	10.3	12.8	8.8	10.4	6.2	9.9	7.0	9.4	5.1	8.0	8.9	15.9	25.6	48.0	8.1	18.3	8.4	6.8	11.9	15.9	0.0	17.9	10.8	37.0	11.5	13.0	27.6	0.0	5.1	6.0	44.2	1.9	8.9	18.2	32.0	25.8	16.9	12.1	29.5	15.8	25.3	3.3	21.0	52.5	55.5	8.2	10.7	37.5	23.4	22.2	0.0	15.2	18.0	6.1	39.3	39.9	42.4	18.3	32.1	12.4	16.9	26.5	0.0	20.6	9.0	13.3	21.9	20.6	9.1	10.3	10.2	36.0	17.2	12.3	0.0	19.7	22.8	23.3	6.8	5.2	15.0	9.2	2.9	10.6	21.3	18.6	9.6
MTHFS	HsT19268	ENSG00000136371	"Methenyltetrahydrofolate synthetase"	P49914	15	79833585-79897379	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Ligase	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	5	"liver: 253.4"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 134.1"	"Group enriched"	"Detected in all"	5	"granulocytes: 134.1;monocytes: 49.1"	"Low cell line specificity"	"Detected in many"											"HPA008067, HPA054177"	Approved		Supported	Cytosol		NA	NA		13000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 62: Liver - Hemostasis"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Cytosol		"HPA008067: AB_1078882, HPA054177: AB_2682405"	"unprognostic (4.57e-2)"	"unprognostic (9.76e-2)"	"unprognostic (6.11e-2)"	"unprognostic (1.82e-1)"	"prognostic unfavorable (8.52e-4)"	"unprognostic (9.13e-3)"	"prognostic favorable (1.29e-6)"	"unprognostic (1.34e-2)"	"unprognostic (1.03e-1)"	"unprognostic (6.18e-3)"	"unprognostic (2.91e-2)"	"unprognostic (2.76e-1)"	"prognostic favorable (2.04e-4)"	"unprognostic (1.36e-1)"	"unprognostic (2.85e-1)"	"unprognostic (7.60e-2)"	"unprognostic (2.90e-1)"	21.9	19.8	8.0	4.6	8.2	5.0	19.0	9.6	12.7	9.9	6.9	12.0	13.7	9.0	10.3	10.1	9.4	7.0	19.0	8.0	9.2	53.1	253.4	17.8	6.4	8.7	9.3	8.6	32.8	26.3	21.5	8.3	9.1	19.5	6.4	5.9	13.6	5.5	20.2	6.2	14.5	6.2	8.8	14.9	19.5	12.1	8.7	10.6	15.9	11.1	10.8	12.4	9.9	9.1	12.6	35.8	5.0	2.6	15.8	12.0	11.9	8.8	13.0	16.4	10.5	34.5	22.4	15.1	25.1	15.5	15.0	19.5	31.9	10.7	15.4	14.7	28.4	14.8	22.9	39.8	25.3	7.8	0.8	17.5	27.8	8.1	23.0	19.6	7.4	16.0	28.8	12.0	17.4	36.0	10.2	36.1	15.6	51.4	17.0	10.8	17.2	25.8	35.1	34.3	8.9	4.8	25.1	14.2	43.8	20.0	17.3	13.0	3.3	5.7	11.1	3.6	7.1	6.8	20.2	17.8	3.3	25.9	6.2	17.5	25.7	73.5	9.4	35.3	12.4	13.5	13.7	12.9	12.3	11.1	16.5	12.6	134.1	17.8	49.1	13.3	15.7	19.1	8.0	8.2	9.6	12.7	8.0	9.2	8.7	9.3	9.1	8.8	8.7	9.1	11.3	19.2	44.0	0.0	20.7	10.7	9.9	63.0	35.9	0.0	25.5	32.5	0.7	58.6	34.3	22.0	0.0	68.1	10.1	10.0	64.6	55.8	2.2	11.9	7.8	10.5	17.6	36.6	0.0	75.7	37.1	13.5	39.8	11.0	8.8	7.2	21.8	205.5	45.7	0.0	0.0	18.7	24.4	22.1	34.8	3.8	13.7	29.3	21.4	0.0	150.8	0.0	35.0	0.0	0.0	75.3	35.9	15.8	13.3	13.3	101.7	201.6	29.9	0.0	13.1	8.4	10.5	6.7	8.5	21.1	8.1	253.8	22.2	9.2	24.9	7.7
QDPR	"DHPR, PKU2, SDR33C1"	ENSG00000151552	"Quinoid dihydropteridine reductase"	P09417	4	17460261-17512206	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Tetrahydrobiopterin biosynthesis"	Oxidoreductase	"Disease variant, Phenylketonuria"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 752.2;choroid plexus: 301.8"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA058951, HPA065649"	Enhanced		Approved	Mitochondria		NA	NA		2500000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 70: Brain - Nervous system development"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA058951: AB_2683861, HPA065649: AB_2685526"	"unprognostic (1.30e-2)"	"unprognostic (4.29e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.21e-1)"	"unprognostic (1.20e-1)"	"unprognostic (3.29e-3)"	"unprognostic (3.80e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.45e-1)"	"unprognostic (6.82e-3)"	"unprognostic (2.07e-1)"	"prognostic favorable (7.84e-6)"	"unprognostic (1.58e-1)"	"unprognostic (2.60e-1)"	"unprognostic (9.01e-2)"	"unprognostic (3.19e-1)"	66.6	74.3	515.1	10.2	720.1	15.1	26.4	696.9	571.9	15.8	301.8	21.2	25.6	16.5	40.1	15.6	17.3	17.7	43.4	457.6	578.5	110.1	197.2	23.3	11.9	663.0	752.2	18.3	28.8	49.9	32.7	11.8	688.6	28.7	17.0	40.1	36.3	19.5	108.6	16.2	23.9	17.9	524.9	14.3	23.7	12.4	602.6	13.6	22.1	61.2	13.3	14.5	15.1	663.7	33.1	62.5	30.2	35.8	66.1	32.3	41.5	43.2	22.3	47.5	41.6	52.2	46.4	12.2	28.0	30.3	50.8	18.4	40.3	58.4	33.7	35.3	7.3	34.8	33.4	128.3	37.3	46.2	2.9	40.8	35.6	31.6	40.3	25.9	24.5	33.2	37.0	29.0	50.6	19.2	65.0	77.8	44.8	36.7	45.4	27.0	21.0	52.2	48.2	17.5	47.1	64.3	31.9	6.7	156.6	35.0	15.7	19.0	37.7	23.6	41.1	26.5	38.2	43.1	67.7	85.3	52.0	43.1	41.7	0.3	38.9	3.0	31.3	61.3	29.8	18.6	33.1	32.3	48.3	18.3	37.4	32.6	1.1	29.8	48.4	115.1	20.3	34.4	515.1	720.1	696.9	571.9	457.6	578.5	663.0	752.2	688.6	524.9	602.6	663.7	20.3	28.9	31.5	10.7	14.8	20.0	21.3	32.2	18.8	36.2	37.6	28.3	74.4	50.1	19.5	38.6	8.4	69.6	22.8	13.7	109.5	41.1	1.0	11.8	19.1	17.2	174.3	30.1	23.1	23.4	34.2	27.1	27.5	17.8	25.4	42.3	20.7	337.6	80.3	82.4	21.9	31.1	34.6	38.1	23.9	4.8	22.7	32.2	152.9	12.2	23.4	387.2	16.5	15.1	481.3	16.9	11.6	38.0	23.6	23.2	41.4	527.2	6.2	31.4	26.3	27.5	25.4	3.3	58.9	29.7	16.1	18.3	18.5	90.0	35.7	17.3