Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AC093512.2 ENSG00000285043 "Uncharaterized LOC112694756" 16 30053090-30070420 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "tongue: 94.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 1.5 1.5 7.5 2.0 8.8 3.4 7.9 6.5 10.3 5.4 9.7 2.3 0.6 1.8 1.1 1.6 4.3 2.3 6.7 9.7 8.0 1.3 0.6 3.2 3.1 7.3 8.4 2.8 1.4 3.0 2.2 7.8 3.1 1.1 2.4 2.3 8.1 17.1 1.3 0.7 2.6 7.5 2.6 2.0 5.2 7.6 9.6 5.6 94.4 3.6 3.7 6.7 7.5 17.6 3.5 11.3 2.6 9.0 2.8 7.5 12.6 9.8 38.2 7.5 9.4 45.6 11.0 12.5 3.3 11.9 25.4 20.2 6.7 8.2 16.4 11.3 15.5 13.1 20.1 19.9 4.2 9.0 0.9 19.3 21.7 8.0 14.0 7.2 2.4 12.9 24.3 9.3 9.6 15.4 3.9 3.2 12.6 14.4 7.2 42.0 27.0 1.6 11.0 9.1 2.0 3.4 2.8 1.1 9.5 7.6 3.3 14.3 4.3 6.8 10.1 13.2 10.7 14.3 14.0 21.1 6.6 0.1 6.3 0.1 4.8 2.6 6.6 6.5 6.3 5.1 6.2 5.7 7.4 5.8 0.8 4.5 2.5 5.3 5.3 15.3 7.5 8.8 6.5 10.3 9.7 8.0 7.3 8.4 7.8 7.5 7.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "adrenal gland: 3039.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 649.2;Cytotrophoblasts: 1105.1;Extravillous trophoblasts: 1284.9;Ionocytes: 697.8;Syncytiotrophoblasts: 2022.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 1667.3;BJ hTERT+: 3096.2;RPTEC TERT1: 1447.8;U-87 MG: 1343.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935" "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.00e-4)" 65.1 3039.1 83.1 38.4 89.3 21.9 52.3 91.8 97.4 41.4 80.9 40.1 20.5 42.4 44.0 28.2 38.7 40.2 208.2 84.1 92.5 218.0 19.3 55.0 74.6 101.6 96.9 60.5 34.4 111.2 76.5 203.7 104.9 34.4 30.9 36.5 41.9 332.7 330.0 26.6 50.8 39.6 91.4 62.8 51.4 44.9 88.7 54.9 44.3 396.9 62.5 67.3 35.0 101.4 184.2 1667.3 186.5 261.4 785.9 212.3 494.6 177.2 3096.2 259.3 335.0 75.8 170.6 0.0 79.2 301.5 1143.3 78.6 204.0 175.3 206.6 65.2 168.2 93.4 225.0 230.1 1117.9 0.1 0.8 196.9 133.4 367.6 98.3 252.8 370.3 181.1 0.1 62.4 292.4 3.5 283.3 131.0 309.2 13.9 1.8 292.9 116.5 138.8 1447.8 915.5 137.1 301.6 1261.5 1.5 134.3 121.3 0.6 140.6 289.6 254.5 116.0 22.7 195.6 168.2 196.9 470.0 1343.5 0.7 153.0 125.7 106.4 5.6 147.6 72.3 135.2 133.0 124.7 144.5 145.3 121.7 162.9 156.7 8.5 119.7 39.2 20.4 94.9 230.2 83.1 89.3 91.8 97.4 84.1 92.5 101.6 96.9 104.9 91.4 88.7 101.4 34.1 12.8 19.4 9.1 50.3 20.6 55.3 66.1 20.5 36.2 11.7 27.9 202.4 25.8 26.4 649.2 8.4 1105.1 35.1 2.3 164.4 112.7 5.0 6.1 20.9 50.9 31.0 20.2 10.5 41.5 1284.9 100.3 20.4 5.9 53.8 59.8 82.1 2.6 394.1 72.3 18.7 15.1 697.8 172.8 53.9 14.5 79.2 127.7 30.2 14.0 76.3 49.3 66.9 5.5 12.4 51.0 4.5 77.5 72.6 25.6 0.3 60.2 24.9 24.1 59.2 98.9 54.5 22.6 100.2 10.5 11.6 2022.4 49.9 70.5 6.7 54.2 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420560-101449664 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "intestine: 5736.6;kidney: 7181.0;liver: 11160.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 20078.3;Proximal tubular cells: 7956.0" "Cancer enriched" "Detected in many" 31 "liver cancer: 1414.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 21.4;NB-4: 21.0;RPMI-8226: 28.6;SH-SY5Y: 20.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002198, CAB020827" Enhanced NA NA 560000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB020827: , HPA002198: AB_1078129" "unprognostic (6.58e-3)" "unprognostic (2.83e-1)" "unprognostic (1.43e-3)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (7.48e-2)" "unprognostic (1.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (1.96e-2)" 3.3 1.4 0.4 17.0 0.7 0.0 0.7 1.0 2.3 0.2 0.0 30.1 4073.8 2.8 1.0 0.7 0.4 176.9 1.0 2.4 0.0 7181.0 11160.8 0.5 4.9 0.0 0.0 0.5 292.7 0.0 5.6 0.4 0.0 2.1 5.6 0.3 0.3 0.0 0.4 0.5 5736.6 7.0 0.0 2.0 34.3 1.1 0.0 0.7 0.3 0.0 0.8 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.5 0.0 4.5 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.2 0.0 1.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.3 21.0 0.4 0.5 0.0 0.3 4.6 28.6 0.0 0.0 4.3 20.6 2.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 1.0 7.1 0.3 0.5 0.7 2.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.0 2.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 39.4 0.0 0.0 0.3 0.0 1.1 0.0 0.0 1.1 308.8 0.8 150.8 0.0 0.0 0.0 13.5 620.3 4.9 0.0 0.0 0.4 3.6 0.0 50.8 0.5 253.3 0.1 0.0 0.0 0.3 0.0 0.0 49.2 3225.4 0.2 3.3 0.2 464.9 0.0 66.2 0.0 0.0 0.0 38.1 0.0 0.0 3.6 0.3 0.0 0.0 0.3 182.1 997.4 0.0 0.1 0.0 20078.3 7956.0 0.2 0.6 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.3 20.6 0.2 412.7 0.0 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 AMIGO3 ENSG00000176020 "Adhesion molecule with Ig like domain 3" Q86WK7 3 49716829-49719684 "Metabolic proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Enteroendocrine cells: 1.2;Microglial cells: 1.0;NK-cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 11.0" "Lineage enriched" "Detected in many" 10 "dendritic cells: 11.0" "Cell line enhanced" "Detected in many" "CACO-2: 3.4;HeLa: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.33e-2)" "unprognostic (5.15e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-1)" "unprognostic (2.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.92e-3)" "unprognostic (3.75e-3)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (7.56e-2)" "unprognostic (7.85e-3)" "unprognostic (3.10e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (2.84e-1)" "unprognostic (3.58e-3)" 0.6 0.8 0.5 0.2 0.4 1.5 0.5 1.4 0.8 0.7 0.1 0.5 0.4 0.7 0.5 1.0 0.8 0.2 0.9 0.3 0.7 0.6 1.9 0.9 0.5 1.0 0.3 1.0 1.6 0.0 3.1 0.1 0.3 1.1 0.0 0.1 0.9 0.3 3.4 3.0 0.8 0.0 0.0 1.1 1.0 1.7 0.4 0.3 0.9 0.0 0.1 0.5 0.6 0.5 0.4 0.4 0.3 0.6 1.9 0.2 1.3 0.3 0.0 0.2 0.1 3.4 0.5 0.0 0.4 0.7 0.1 1.8 0.0 0.2 0.0 1.9 1.0 0.0 4.2 2.2 0.0 1.0 2.7 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.6 0.6 0.0 1.7 1.6 1.7 0.4 0.5 0.5 0.4 0.6 0.4 0.0 1.9 1.5 2.5 1.0 0.2 0.5 0.0 0.2 0.5 1.1 0.3 1.8 1.2 0.3 2.2 1.4 0.5 0.0 1.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.2 0.9 0.1 0.1 0.3 0.6 0.0 1.0 0.0 11.0 0.5 0.3 0.5 0.4 1.4 0.8 0.3 0.7 1.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 DLX4 "BP1, DLX7, DLX8, DLX9" ENSG00000108813 "Distal-less homeobox 4" Q92988 17 49968970-49974959 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.7;skin 1: 3.0" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 77.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 22.9;CACO-2: 16.8;GAMG: 15.3;HAP1: 11.2;K-562: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059933 Uncertain Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA059933: AB_2684169" "unprognostic (8.12e-2)" "unprognostic (2.48e-1)" "unprognostic (1.26e-2)" "unprognostic (2.29e-3)" "unprognostic (7.49e-2)" "unprognostic (2.71e-1)" "unprognostic (9.35e-3)" "unprognostic (2.85e-2)" "unprognostic (8.73e-2)" "unprognostic (5.93e-2)" "unprognostic (1.29e-2)" "unprognostic (4.34e-2)" "unprognostic (2.88e-13)" "unprognostic (8.79e-3)" "unprognostic (2.77e-1)" "unprognostic (5.00e-2)" "unprognostic (6.86e-2)" 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.2 0.2 0.8 0.0 0.3 0.2 0.1 3.7 0.5 0.2 0.1 0.0 1.1 0.2 0.0 3.0 0.2 0.0 0.2 0.4 0.1 0.3 0.2 0.1 0.3 0.0 0.5 0.2 0.5 0.2 0.5 1.4 0.0 0.1 0.1 0.0 22.9 0.1 0.1 0.1 0.3 16.8 1.0 0.7 3.3 0.3 15.3 2.3 11.2 0.4 0.1 4.5 5.9 0.4 5.7 1.7 0.0 0.9 3.7 0.0 2.8 0.1 0.0 0.2 0.0 3.5 13.5 0.0 0.0 2.9 0.4 6.0 0.2 3.1 0.0 0.0 5.1 0.6 0.1 0.8 1.9 0.1 0.4 1.9 1.1 3.4 4.1 4.0 0.0 0.0 1.0 0.2 0.0 0.9 0.2 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.0 6.4 0.0 0.0 0.2 2.5 0.4 1.0 2.2 0.0 0.5 0.3 1.9 0.0 0.1 0.0 0.0 12.7 0.1 0.1 0.0 0.3 0.1 1.5 0.1 0.2 0.0 0.0 0.3 0.2 77.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 1.0 1.1 0.4 0.6 16.8 0.1 0.2 0.2 0.3 FAM20B "GXK1, KIAA0475" ENSG00000116199 "FAM20B glycosaminoglycan xylosylkinase" O75063 1 179025804-179076567 "Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007409 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus" Nucleoplasm "HPA007409: AB_10601649" "unprognostic (7.58e-2)" "unprognostic (1.12e-1)" "unprognostic (4.97e-2)" "unprognostic (6.23e-3)" "unprognostic (3.29e-1)" "unprognostic (3.07e-1)" "unprognostic (4.76e-2)" "unprognostic (7.70e-3)" "unprognostic (7.85e-2)" "unprognostic (3.93e-2)" "unprognostic (5.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.76e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" 20.9 22.4 15.0 11.2 17.2 11.7 15.9 12.7 17.1 16.1 7.7 22.2 9.9 18.0 15.4 17.6 15.4 13.6 23.4 18.0 17.2 17.3 16.5 16.3 11.3 14.0 14.6 19.9 11.4 21.4 14.4 17.0 14.5 16.5 14.4 28.7 11.8 19.4 19.6 12.8 11.5 19.4 13.5 12.4 13.6 8.0 15.3 11.5 17.9 25.6 10.8 16.2 12.3 14.7 41.4 37.1 28.2 30.0 49.1 51.4 31.2 33.7 38.3 23.2 20.7 18.7 40.1 21.3 43.2 59.7 19.1 29.3 29.0 24.8 33.8 27.3 19.5 67.9 34.8 23.9 24.5 45.5 41.1 30.1 26.5 31.7 24.5 35.4 29.0 29.2 77.0 30.2 37.5 23.1 19.9 16.4 37.1 46.2 7.9 24.1 29.7 28.4 19.5 46.1 37.5 91.8 35.5 39.7 34.5 39.8 34.4 32.8 30.8 36.7 32.2 51.1 46.0 24.5 48.5 18.2 36.5 21.7 37.3 0.9 0.6 0.2 1.3 0.6 1.3 1.4 0.7 1.1 0.8 1.5 1.1 1.0 0.6 1.6 0.8 1.2 1.0 0.5 15.0 17.2 12.7 17.1 18.0 17.2 14.0 14.6 14.5 13.5 15.3 14.7 16.8 6.4 11.4 16.0 7.5 15.6 12.6 8.9 4.6 15.7 12.2 9.3 40.1 12.8 9.0 18.4 25.0 9.0 9.0 10.6 3.9 8.8 5.2 8.8 17.8 13.8 14.4 43.3 28.3 13.0 7.7 14.6 9.2 14.5 17.1 20.2 9.3 14.2 7.6 38.7 32.0 7.9 10.2 11.6 8.1 5.1 17.7 9.6 16.0 19.7 14.1 9.0 2.1 17.6 32.5 13.7 3.8 21.4 6.2 19.7 5.0 5.9 8.8 21.0 13.1 20.0 17.7 17.6 13.8 9.6 12.9 7.5 8.0 24.1 8.5 24.7 FCSK "FLJ39408, FUK" ENSG00000157353 "Fucose kinase" Q8N0W3 16 70454595-70480274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.2;Cytotrophoblasts: 5.5;Extravillous trophoblasts: 3.0;Hofbauer cells: 5.0;Syncytiotrophoblasts: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA041971: AB_10795648" "unprognostic (4.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.73e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (4.82e-3)" "unprognostic (4.85e-2)" "prognostic favorable (8.91e-4)" "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (8.89e-2)" "prognostic favorable (8.38e-4)" 3.9 7.2 5.4 5.4 7.1 5.0 4.9 8.2 7.7 5.6 7.5 7.5 10.1 4.9 2.4 5.6 5.5 3.8 4.3 5.3 5.0 8.9 8.2 4.8 5.4 6.4 4.6 6.6 8.3 9.1 9.8 3.6 5.7 6.3 3.9 2.9 5.9 4.4 5.5 7.2 7.4 3.1 4.5 6.4 6.6 4.5 5.7 3.8 7.9 2.3 2.8 4.8 4.8 11.1 3.4 4.6 2.5 5.8 1.5 1.8 10.0 1.8 2.8 2.2 3.0 4.2 10.0 2.3 8.8 1.7 0.7 4.8 1.8 4.7 1.6 4.4 6.5 2.9 8.9 4.5 3.7 3.8 2.3 3.0 5.4 2.1 4.4 3.3 4.3 4.6 5.9 2.6 1.8 10.3 4.6 9.2 1.6 5.5 2.7 7.0 0.6 10.4 5.9 5.5 4.0 5.3 10.1 3.7 5.3 1.9 14.8 7.5 5.0 1.8 2.4 4.0 2.2 9.5 5.1 4.8 3.3 3.8 4.2 0.2 1.9 0.8 1.9 1.0 1.6 0.8 1.9 1.9 1.1 1.5 2.6 1.2 1.6 1.2 1.2 1.3 1.4 1.2 5.4 7.1 8.2 7.7 5.3 5.0 6.4 4.6 5.7 4.5 5.7 11.1 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.0 0.0 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 191.7;Cholangiocytes: 343.1;Hepatocytes: 142.3" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 42.9;RH-30: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.2 14.6 10.5 2.0 12.8 2.3 6.6 21.8 10.2 6.3 4.5 7.1 7.1 4.7 36.5 5.5 9.9 5.4 11.3 7.4 12.1 19.1 77.1 4.7 3.3 12.9 13.4 4.8 12.0 10.5 9.7 3.0 12.9 7.8 6.7 9.6 7.5 10.3 41.8 5.7 8.1 4.2 9.3 2.8 6.1 4.2 16.5 4.1 7.7 17.1 3.6 7.0 5.2 12.7 4.8 1.4 9.2 3.9 4.7 16.6 0.8 4.1 6.8 2.3 3.4 0.0 3.8 5.4 13.0 11.0 4.1 2.0 1.6 11.9 4.9 42.9 1.1 3.8 2.9 8.6 12.3 2.3 2.4 23.2 10.2 5.0 7.9 10.0 4.6 6.0 2.7 3.4 15.3 5.2 3.0 3.2 5.8 13.0 5.3 6.5 28.3 2.1 12.9 8.8 7.2 3.2 5.6 3.3 12.0 8.0 2.8 2.3 4.7 4.0 2.6 4.7 2.8 7.5 2.9 4.6 12.9 9.2 3.8 1.5 1.3 1.4 3.0 1.3 2.7 5.1 1.4 3.8 2.2 3.6 2.7 4.3 2.2 2.9 3.4 1.1 2.8 1.8 10.5 12.8 21.8 10.2 7.4 12.1 12.9 13.4 12.9 9.3 16.5 12.7 3.7 54.5 191.7 83.2 7.9 20.9 23.8 45.2 14.2 10.1 33.1 66.9 29.9 343.1 40.4 12.9 12.5 9.3 3.7 4.2 17.6 62.6 14.0 33.2 7.5 6.9 2.4 12.2 20.4 42.5 4.5 7.6 7.1 20.4 10.1 5.3 5.3 142.3 11.4 8.4 33.7 11.3 22.4 8.8 7.6 11.4 1.8 6.7 35.6 17.8 11.2 12.2 3.1 39.2 36.0 17.7 7.7 3.0 3.4 19.1 14.9 47.9 91.2 16.4 0.0 31.4 8.9 4.6 11.5 13.5 31.5 4.5 5.1 5.9 17.1 35.5 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FN3KRP "FLJ12171, FN3KL" ENSG00000141560 "Fructosamine 3 kinase related protein" Q9HA64 17 82716706-82730328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056172, HPA065831" Approved Approved Nucleoplasm NA NA 44000 "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA056172: AB_2683055, HPA065831: AB_2685565" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (1.54e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.31e-1)" "unprognostic (1.25e-2)" "unprognostic (8.67e-2)" "unprognostic (1.26e-1)" "unprognostic (1.99e-1)" "unprognostic (8.84e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (3.71e-2)" 23.2 22.1 40.6 13.3 43.7 18.8 19.7 43.3 41.3 23.4 35.1 22.9 15.3 23.1 19.4 20.4 20.4 16.6 16.1 41.1 41.7 23.9 29.3 16.3 18.5 42.5 41.6 32.1 19.3 18.4 17.2 21.8 43.2 20.8 18.0 17.8 22.2 23.2 11.4 23.6 19.4 22.1 42.9 20.9 20.6 13.7 41.7 16.6 16.7 10.6 22.8 19.7 20.7 48.3 31.4 122.3 33.6 44.5 15.9 30.3 27.2 56.9 31.8 54.5 44.3 64.9 21.8 25.6 37.0 46.6 50.5 35.3 30.1 43.5 48.7 17.2 54.3 42.6 66.2 77.5 28.3 30.7 23.2 27.8 50.9 51.7 28.1 33.4 39.8 35.9 42.5 15.8 70.7 59.8 58.8 45.2 15.2 68.7 53.5 44.0 83.4 40.3 38.9 58.7 27.6 58.1 93.7 42.7 47.3 57.4 69.8 43.6 34.8 103.3 35.9 74.2 85.3 32.1 37.8 64.8 48.1 38.2 49.0 32.0 21.9 30.6 29.6 24.7 29.5 23.9 28.8 28.8 18.2 24.8 32.5 24.3 3.4 32.1 13.8 36.0 29.7 26.0 40.6 43.7 43.3 41.3 41.1 41.7 42.5 41.6 43.2 42.9 41.7 48.3 14.3 12.8 11.1 5.5 13.9 15.0 26.0 26.0 15.4 18.1 13.3 15.6 6.9 25.8 15.3 11.0 8.4 100.3 20.0 12.2 23.5 20.6 2.0 10.7 13.0 14.8 7.8 31.2 7.6 11.1 45.3 18.1 13.3 22.3 13.3 18.6 10.8 12.1 33.8 3.3 6.7 15.4 22.4 11.2 11.3 4.2 28.3 12.8 23.2 6.5 20.9 36.1 17.5 5.0 11.8 17.8 15.9 31.6 27.6 15.5 11.1 28.2 10.0 18.5 13.1 13.6 20.9 18.3 36.2 18.0 15.3 62.5 17.2 22.3 15.6 24.0 FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198212-74234086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Uncertain Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA072331: " "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (8.18e-3)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (7.88e-2)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" 10.5 10.5 3.7 9.9 5.6 4.2 12.9 5.4 4.9 8.9 6.2 12.0 11.7 8.7 10.6 10.7 9.2 13.2 8.7 4.0 5.0 15.4 14.1 8.9 9.0 5.8 5.4 13.3 10.4 13.5 5.3 10.8 6.2 9.9 11.1 6.8 10.6 8.5 4.9 12.0 12.3 8.8 5.3 10.1 12.6 8.1 5.0 8.5 19.5 5.6 9.8 8.3 6.0 8.3 12.4 10.1 7.5 11.0 17.0 15.8 11.2 16.0 10.6 10.8 12.7 5.7 9.1 7.6 19.2 9.5 12.2 10.3 13.6 14.6 17.1 15.4 5.8 17.3 11.1 9.7 14.1 13.2 12.7 13.1 18.6 10.8 5.1 7.4 11.3 10.5 18.2 8.8 17.1 3.3 7.4 2.7 8.2 15.9 9.1 7.8 17.5 10.8 9.5 8.9 7.8 7.8 11.8 17.1 18.6 2.4 20.6 14.9 10.3 4.7 8.8 25.8 12.2 9.6 7.3 10.2 19.0 12.8 16.2 19.5 20.1 21.7 5.5 20.5 6.5 5.0 5.5 5.2 12.6 6.1 6.2 5.6 6.1 5.8 18.4 1.2 7.6 10.7 3.7 5.6 5.4 4.9 4.0 5.0 5.8 5.4 6.2 5.3 5.0 8.3 7.1 6.4 3.2 0.0 3.0 6.8 4.9 13.3 4.6 7.1 7.6 5.6 10.2 14.3 9.3 11.0 2.1 12.7 2.5 7.8 19.6 5.3 8.9 6.0 4.8 4.9 6.0 9.5 0.0 7.1 11.0 7.0 4.1 4.2 5.1 4.9 6.4 9.8 15.1 3.3 0.0 7.3 6.1 9.4 4.6 7.3 10.2 10.3 5.4 0.0 9.0 10.6 8.2 0.0 0.0 6.5 8.9 5.7 1.2 2.5 11.0 15.3 12.7 5.5 26.3 5.8 7.2 9.7 10.4 5.7 6.5 6.2 5.2 4.9 7.3 3.0 FPGT-TNNI3K ENSG00000259030 "FPGT-TNNI3K readthrough" 1 74198235-74544393 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 8.7" "Cell type enhanced" "Detected in many" "Astrocytes: 13.1;Cardiomyocytes: 10.2;Cone photoreceptor cells: 10.4;Excitatory neurons: 10.3;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.3;CAPAN-2: 2.2;SiHa: 3.1" HPA072331 Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA072331: " "unprognostic (6.29e-2)" "unprognostic (4.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-3)" "unprognostic (8.37e-2)" "unprognostic (1.70e-2)" "unprognostic (6.63e-2)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (8.37e-2)" "unprognostic (6.76e-3)" "unprognostic (3.20e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (7.87e-3)" 2.4 1.2 0.8 0.5 1.3 0.4 1.4 2.9 1.9 1.1 0.0 1.8 0.3 1.4 0.8 1.4 1.3 0.8 8.7 1.0 1.2 1.6 0.4 1.4 0.6 1.0 1.0 1.3 0.5 1.0 1.4 0.5 1.4 1.2 0.7 3.4 0.9 1.3 3.5 2.1 0.8 1.5 1.1 1.5 1.0 0.8 0.9 0.2 1.1 1.8 0.6 1.3 1.1 2.4 0.0 0.5 0.3 0.7 0.4 2.3 0.0 1.0 0.5 0.1 0.1 0.5 2.2 0.0 1.5 0.1 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.2 0.1 0.9 0.9 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.1 0.0 0.8 0.4 1.1 1.8 0.0 0.2 0.0 0.5 1.5 3.1 0.1 0.1 0.0 0.0 1.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.9 0.4 0.5 0.4 1.3 1.6 1.4 0.4 1.9 1.2 0.9 1.4 0.8 0.9 0.9 1.8 0.9 1.8 0.4 0.5 0.8 1.6 1.6 0.8 1.3 2.9 1.9 1.0 1.2 1.0 1.0 1.4 1.1 0.9 2.4 0.5 3.2 1.1 13.1 0.9 0.1 0.5 0.2 0.0 4.9 0.6 0.9 10.2 1.5 0.7 0.0 10.4 0.2 0.2 0.5 0.0 0.2 1.4 0.6 0.3 0.9 3.0 0.0 10.3 1.0 0.2 1.3 0.0 0.2 2.5 1.6 1.8 0.5 0.2 5.0 11.2 0.2 0.0 0.9 0.3 0.6 2.8 0.7 1.8 7.5 0.1 1.1 0.0 17.1 26.7 1.3 1.6 0.7 0.3 0.3 0.0 1.4 1.6 2.7 0.0 1.5 1.1 2.1 1.7 0.1 0.1 0.0 0.4 0.8 0.5 0.2 GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 850000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favorable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 36.3 37.2 21.6 27.7 21.1 52.3 34.0 21.4 25.9 28.6 21.7 45.9 69.2 24.8 19.2 88.7 24.0 29.3 32.1 20.7 21.3 37.5 86.6 28.4 29.1 23.5 21.9 19.0 99.5 22.8 44.0 24.4 22.8 45.0 37.6 6.5 70.9 24.2 30.2 81.5 52.4 19.4 20.2 35.7 111.4 49.4 21.0 26.6 32.1 18.4 27.1 31.0 36.0 22.5 85.6 67.1 29.2 99.7 28.6 26.1 54.1 70.3 73.0 50.2 38.1 78.5 94.3 37.5 64.6 52.5 21.2 60.6 47.8 100.8 23.2 101.7 53.8 58.7 103.0 93.4 57.2 42.2 67.1 30.3 47.4 31.7 127.3 42.2 84.3 61.9 66.4 57.0 41.2 267.5 39.8 53.2 45.8 267.7 87.1 47.1 26.3 122.3 106.1 94.8 67.3 45.9 53.3 100.2 73.0 23.0 133.5 58.8 75.5 34.8 132.0 35.1 67.6 34.1 30.2 29.0 52.8 91.6 54.7 34.9 27.4 42.9 40.3 38.5 43.0 35.2 43.1 46.8 30.1 40.1 31.5 38.5 31.0 63.6 33.8 54.5 57.5 45.7 21.6 21.1 21.4 25.9 20.7 21.3 23.5 21.9 22.8 20.2 21.0 22.5 32.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 82.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 156.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 87.7 1.7 0.0 0.0 0.0 GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245605 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 106.0;salivary gland: 105.4;stomach 1: 97.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 208.5;Gastric mucus-secreting cells: 276.8;Intestinal goblet cells: 367.6;Proximal enterocytes: 190.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced NA NA 72000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA031528: AB_10601016" "unprognostic (5.94e-2)" "unprognostic (3.92e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.89e-4)" "unprognostic (4.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-3)" "unprognostic (7.15e-2)" "unprognostic (2.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-1)" "prognostic favorable (5.93e-4)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" 10.7 7.6 8.6 30.1 7.1 9.1 14.6 5.8 7.1 29.4 9.7 87.7 106.0 7.8 10.4 65.8 11.5 20.5 9.5 7.6 7.0 19.6 31.1 9.0 14.2 6.6 6.9 6.7 43.8 20.5 12.9 7.1 6.7 18.3 82.4 1.5 105.4 8.0 5.1 10.6 87.3 10.3 6.1 11.4 97.1 9.2 7.3 13.9 11.9 4.9 20.8 13.7 14.2 6.2 45.9 10.6 7.4 52.6 11.8 32.0 17.9 12.5 25.7 22.7 21.2 23.1 26.1 21.7 37.3 13.6 22.4 18.3 22.9 43.8 26.2 30.0 28.8 21.0 11.2 110.3 13.2 34.2 22.5 35.6 14.9 18.0 37.2 21.9 26.9 73.0 13.9 9.8 14.7 26.3 49.0 40.1 11.4 246.4 36.0 24.8 16.8 112.4 55.4 59.5 41.4 9.9 11.5 17.7 28.8 33.6 16.4 21.4 11.7 17.4 13.1 17.7 22.5 22.1 33.6 23.1 11.4 23.6 23.4 7.0 12.9 1.5 7.8 8.3 10.3 10.5 9.4 7.5 14.5 5.0 7.6 10.8 3.8 13.1 6.8 6.1 13.2 8.3 8.6 7.1 5.8 7.1 7.6 7.0 6.6 6.9 6.7 6.1 7.3 6.2 19.7 0.0 4.5 40.8 19.8 4.2 20.1 38.3 27.3 3.7 33.1 19.3 2.9 12.8 40.5 38.6 0.0 18.7 6.5 104.1 119.3 36.5 5.7 7.8 7.3 23.0 111.7 9.7 208.5 69.7 30.8 12.4 276.8 11.9 4.5 13.2 18.2 19.6 13.5 8.4 167.5 367.6 50.8 10.9 7.6 4.6 12.2 11.0 23.2 143.4 14.7 3.3 9.2 83.9 50.2 47.0 85.5 16.6 53.1 40.7 190.7 38.1 38.3 0.7 13.1 5.8 16.6 6.5 33.1 20.1 6.1 16.7 18.6 13.4 165.1 43.5 GMPPA ENSG00000144591 "GDP-mannose pyrophosphorylase A" Q96IJ6 2 219498884-219506989 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035512, HPA035513" Approved Approved Nucleoplasm NA NA 51000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA035512: AB_2674660, HPA035513: AB_10671934" "unprognostic (3.43e-1)" "unprognostic (3.95e-2)" "unprognostic (7.75e-3)" "unprognostic (1.40e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.57e-1)" "unprognostic (2.39e-1)" "unprognostic (2.25e-1)" "unprognostic (1.17e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.90e-10)" "prognostic favorable (5.24e-4)" "unprognostic (1.28e-1)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" 22.6 25.8 19.3 23.9 20.1 19.0 21.6 20.1 22.6 32.1 22.4 29.7 28.8 26.4 68.7 25.5 24.6 19.7 27.1 20.1 20.5 25.7 68.5 20.9 20.7 20.5 19.8 20.1 60.3 24.7 48.5 21.2 20.0 37.3 32.3 8.0 40.1 23.4 22.8 17.8 30.0 26.2 19.6 35.2 32.5 9.6 21.3 13.2 28.6 12.6 23.8 25.2 23.1 19.8 43.4 36.0 21.2 37.8 79.5 70.6 56.4 73.8 98.6 85.2 105.2 66.8 40.5 23.4 51.1 107.7 54.3 40.1 39.7 63.9 73.3 45.3 35.0 45.5 35.7 119.3 72.0 24.1 51.7 54.3 50.7 79.9 89.9 43.9 52.8 29.7 82.3 66.3 66.8 55.5 23.8 45.3 21.7 52.8 38.5 18.6 22.9 42.4 48.6 30.1 27.4 24.0 31.0 46.3 52.1 44.4 31.5 38.8 30.9 49.2 33.6 89.4 40.9 45.4 19.4 28.9 100.4 26.7 55.8 76.0 52.6 37.3 30.1 56.0 35.0 32.1 23.4 31.9 43.5 24.1 17.3 15.7 11.8 36.4 59.3 43.9 34.8 35.2 19.3 20.1 20.1 22.6 20.1 20.5 20.5 19.8 20.0 19.6 21.3 19.8 12.5 16.0 14.4 5.5 18.8 5.6 12.8 25.2 6.2 6.1 20.9 13.5 13.2 10.0 20.1 16.5 6.2 37.6 16.6 37.7 35.2 24.3 1.3 8.5 15.8 9.5 10.8 19.1 3.1 30.0 79.8 19.2 38.7 14.4 19.0 13.3 11.0 36.3 33.7 1.7 3.6 61.6 10.2 17.6 10.0 3.4 18.3 16.5 12.4 1.9 15.9 11.1 12.3 1.0 4.9 19.0 37.6 13.5 50.3 15.1 45.9 36.8 11.6 4.7 13.1 7.9 27.1 4.4 6.5 9.9 8.5 47.2 13.5 10.7 29.1 15.1 GMPPB KIAA1851 ENSG00000173540 "GDP-mannose pyrophosphorylase B" Q9Y5P6 3 49716844-49723973 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 130.2;Syncytiotrophoblasts: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014657 Uncertain NA NA 38000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "HPA014657: AB_1849852" "unprognostic (3.48e-2)" "unprognostic (9.84e-2)" "unprognostic (2.77e-2)" "prognostic favorable (6.19e-6)" "unprognostic (1.01e-2)" "unprognostic (5.11e-3)" "unprognostic (1.54e-2)" "unprognostic (4.01e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-2)" "unprognostic (5.01e-3)" "unprognostic (5.73e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" 14.5 30.1 6.1 16.1 6.0 11.8 15.3 5.7 6.6 20.8 9.2 23.1 14.5 18.6 14.5 26.3 19.5 9.5 18.2 6.0 6.3 17.5 44.2 21.4 13.0 6.7 6.5 14.0 57.4 10.1 39.4 7.5 6.1 27.9 12.2 4.1 35.4 14.7 13.4 14.9 21.8 9.4 6.1 27.9 26.2 9.6 6.8 9.3 26.3 5.7 13.0 15.9 16.8 5.9 31.8 27.0 21.0 12.3 15.6 10.8 21.7 36.1 17.1 29.0 26.1 18.7 21.5 17.6 15.8 18.1 22.2 16.7 18.6 29.0 10.6 17.2 14.5 13.5 27.2 21.5 31.1 19.0 19.6 8.2 15.1 40.0 34.8 11.3 24.8 20.2 10.4 32.0 16.3 20.3 27.3 11.7 12.2 22.5 34.3 9.2 12.5 30.4 16.3 24.0 13.8 16.0 15.7 36.5 12.5 10.6 20.6 13.9 21.9 25.7 25.0 33.4 38.8 33.7 11.1 13.6 25.4 14.7 28.6 22.1 15.6 6.7 18.3 21.3 18.6 22.7 15.9 19.3 14.7 22.5 11.8 14.6 4.0 11.3 21.8 61.8 12.0 14.8 6.1 6.0 5.7 6.6 6.0 6.3 6.7 6.5 6.1 6.1 6.8 5.9 7.3 9.6 17.2 1.6 35.4 0.8 22.8 0.7 2.8 3.7 34.1 14.1 4.5 15.7 3.8 18.4 2.1 28.5 28.5 43.6 29.4 39.8 10.0 18.3 14.3 10.7 16.7 9.9 0.8 50.6 67.2 15.5 34.7 17.8 0.0 11.2 9.3 28.4 39.0 6.7 0.8 55.9 0.0 10.7 1.7 10.0 15.5 13.7 1.8 1.0 40.9 5.8 19.6 1.0 0.4 31.9 27.1 7.5 130.2 40.9 29.2 25.7 14.4 6.2 0.0 5.3 12.2 22.9 12.6 14.7 1.7 79.5 14.7 13.1 32.8 37.1 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.5;retina: 46.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 31.5;Distal enterocytes: 29.0;Ductal cells: 32.6;Endometrial ciliated cells: 50.0;Glandular and luminal cells: 55.2;Muller glia cells: 126.9;Proximal enterocytes: 56.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cell line enhanced" "Detected in some" "A549: 40.1;CACO-2: 57.5;CAPAN-2: 111.4;EFO-21: 33.9;GAMG: 45.4;Hep G2: 33.6;RPTEC TERT1: 81.9" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA064198: AB_2685210, HPA064230: AB_2685219" "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" 0.1 0.0 1.1 2.7 1.3 0.0 0.0 1.4 1.0 1.1 1.4 6.8 53.5 0.9 0.0 0.1 4.6 6.8 0.0 1.0 1.1 13.3 4.6 1.5 1.0 1.3 2.1 0.0 6.2 0.0 0.3 0.0 1.7 0.0 4.2 46.8 0.1 0.0 0.0 0.1 48.0 0.5 1.4 0.3 1.1 1.0 1.0 5.2 9.3 0.0 0.2 0.0 0.1 1.2 1.2 40.1 0.2 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.1 57.5 111.4 0.0 33.9 0.3 45.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 33.6 2.7 0.0 0.0 0.0 0.3 0.4 3.2 0.6 0.0 11.3 0.0 0.0 0.7 0.1 0.2 0.1 0.0 11.9 1.3 0.0 1.2 0.1 81.9 0.1 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.4 1.6 0.2 0.8 0.0 0.1 0.0 8.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.5 0.0 3.1 1.0 0.0 0.0 5.8 2.3 0.0 0.2 0.0 0.0 5.4 1.0 1.1 1.3 1.4 1.0 1.0 1.1 1.3 2.1 1.7 1.4 1.0 1.2 0.0 3.2 4.8 11.8 0.7 0.0 0.0 0.3 0.0 1.9 0.0 0.0 1.0 31.5 1.0 16.5 0.0 0.0 0.2 29.0 1.9 32.6 0.6 50.0 4.5 0.5 0.0 0.0 0.4 7.3 0.0 0.2 1.5 55.2 0.0 0.0 0.0 0.4 0.1 3.3 0.5 5.6 0.0 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 126.9 0.0 0.0 0.5 25.5 12.7 0.0 0.3 0.0 56.3 15.7 0.3 5.1 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.3 0.1 5.6 0.3 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "intestine: 121.2;kidney: 104.4;liver: 180.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 428.5;Proximal enterocytes: 1858.7;Proximal tubular cells: 1019.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 32.8;Hep G2: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 2.2 4.6 4.2 3.0 4.3 1.7 2.0 7.1 5.9 2.6 1.2 4.2 112.4 3.8 0.6 2.4 4.3 1.3 1.4 4.8 3.9 104.4 180.5 1.6 1.9 5.4 4.0 3.6 9.4 2.6 1.4 0.5 5.5 1.6 1.2 1.5 4.4 1.4 3.8 2.4 121.2 1.9 3.6 2.0 2.9 3.2 3.8 0.7 1.1 2.0 1.2 1.8 2.3 4.7 25.0 18.5 2.8 11.0 2.0 0.5 2.5 1.7 1.1 2.3 1.4 9.0 5.3 3.7 5.8 0.1 2.6 10.7 9.4 3.1 0.8 8.8 17.2 32.8 5.2 48.0 1.1 4.6 3.7 0.1 1.3 2.7 0.2 1.2 2.1 5.1 5.9 6.1 0.2 16.0 5.4 3.6 4.0 22.3 7.2 18.9 1.4 20.9 2.7 3.0 10.2 15.8 3.6 6.2 6.9 1.0 2.7 2.0 1.9 0.7 3.6 1.6 6.5 7.5 14.4 6.3 3.0 10.7 1.8 0.0 5.4 0.3 4.1 3.1 5.5 3.8 6.6 6.0 4.9 3.6 4.7 5.8 0.5 4.9 1.4 6.1 4.7 4.9 4.2 4.3 7.1 5.9 4.8 3.9 5.4 4.0 5.5 3.6 3.8 4.7 6.5 3.2 3.7 1.6 6.8 3.6 2.6 0.8 6.8 3.6 4.7 5.8 1.8 20.0 1.0 40.5 2.1 4.1 1.3 7.4 129.1 3.2 1.2 0.1 0.6 5.5 6.0 15.6 3.4 3.0 3.6 2.4 3.6 0.3 4.5 2.9 9.7 428.5 8.3 6.7 2.7 89.6 4.1 11.9 2.0 6.2 1.8 10.8 8.8 0.0 1.9 9.8 4.1 2.5 2.3 2.1 95.7 1.5 8.0 0.7 1858.7 1019.7 0.0 5.4 0.0 5.0 5.0 1.1 5.8 4.6 6.8 9.4 6.8 0.8 82.6 2.2 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554513 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoli "Intermediate filaments" "HPA036347: AB_2675076" "unprognostic (3.03e-1)" "unprognostic (4.93e-2)" "unprognostic (4.99e-2)" "unprognostic (3.14e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (2.48e-1)" "unprognostic (1.31e-1)" "unprognostic (8.90e-2)" "unprognostic (1.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.80e-2)" "unprognostic (3.32e-2)" "unprognostic (3.40e-1)" "unprognostic (3.54e-2)" "unprognostic (4.65e-2)" 3.8 4.6 4.5 3.5 5.0 7.5 3.7 4.9 5.6 4.7 1.9 5.0 2.4 5.0 3.6 4.7 4.3 2.3 4.5 6.2 4.2 4.4 5.3 3.2 5.2 3.3 3.8 4.8 6.0 3.4 4.0 3.0 3.8 4.1 3.1 4.3 3.6 3.1 7.0 6.0 4.8 3.9 2.7 8.8 4.5 3.7 4.6 3.8 3.4 4.5 5.1 4.5 3.8 4.0 6.4 9.1 5.0 15.2 6.6 4.0 5.4 6.3 4.1 6.4 6.8 12.6 8.6 17.9 7.3 7.1 5.5 8.3 10.2 8.6 10.9 7.3 5.5 12.2 14.7 9.9 6.6 10.4 6.4 5.8 2.6 13.6 11.8 3.7 7.6 7.8 14.3 7.3 6.6 11.2 10.2 9.2 6.9 5.0 8.7 12.7 11.7 8.3 5.1 5.8 9.7 4.4 9.7 12.1 8.1 5.1 7.9 4.8 10.0 10.1 8.1 7.2 10.6 6.1 6.2 31.9 9.4 11.4 4.9 3.5 1.9 1.6 3.1 1.9 3.2 2.9 4.5 2.9 1.3 3.7 4.6 3.8 1.2 1.7 3.2 3.5 3.2 1.2 4.5 5.0 4.9 5.6 6.2 4.2 3.3 3.8 3.8 2.7 4.6 4.0 15.0 19.2 19.5 9.4 16.2 15.4 6.9 6.9 10.8 17.1 9.8 13.2 15.0 11.5 7.4 7.3 14.6 14.8 17.3 6.7 15.6 8.9 6.0 13.7 19.7 15.2 6.7 11.6 18.9 8.6 12.6 15.3 11.7 15.6 5.1 18.3 14.3 13.2 9.1 10.1 18.5 10.9 4.1 13.8 7.3 17.0 9.6 8.6 1.8 10.3 13.4 8.1 12.3 13.0 20.1 9.0 6.2 12.8 17.9 7.3 7.6 10.7 9.0 18.2 0.0 22.6 12.7 11.7 21.5 16.0 14.8 12.7 17.3 19.1 13.2 7.3 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 28.3;liver: 50.2;skeletal muscle: 111.6;tongue: 40.8" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 15.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.5;Hep G2: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 28.3 0.5 0.4 0.1 0.5 0.4 9.2 0.3 0.5 0.1 0.1 0.4 0.1 0.1 0.6 1.1 0.1 0.3 0.3 0.4 0.4 1.1 50.2 0.2 0.5 0.5 0.4 0.0 1.2 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.7 0.2 111.6 0.8 0.5 0.1 0.4 0.3 0.4 0.4 0.4 0.4 1.0 40.8 0.6 0.2 0.2 0.5 0.2 0.1 0.2 0.4 8.5 0.1 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.4 0.1 0.0 0.4 0.3 0.1 0.2 0.3 0.3 0.7 0.2 0.1 3.2 0.0 0.0 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.8 0.1 1.4 0.1 0.5 0.4 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 1.0 0.1 0.7 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.7 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.4 0.5 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 15.9 0.1 0.0 1.5 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 83.3" "Cell type enhanced" "Detected in many" "Astrocytes: 105.1;Cardiomyocytes: 79.0;Late spermatids: 158.2;Rod photoreceptor cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 20.8;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 8 "dendritic cells: 23.8;granulocytes: 20.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA049975: AB_2680977, HPA063575: AB_2685046" "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favorable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (1.86e-2)" 4.3 6.8 13.2 8.3 14.5 23.5 6.4 8.6 15.2 9.1 42.5 22.2 32.2 5.0 11.6 9.6 5.7 5.8 36.0 13.9 11.4 29.7 4.0 13.3 7.0 13.3 13.8 5.2 16.0 15.3 23.1 3.9 12.2 4.8 24.1 83.3 7.6 4.1 49.5 8.1 22.2 5.0 9.7 15.0 15.5 7.0 19.3 20.2 51.7 42.7 6.7 4.2 4.2 18.4 15.0 6.5 4.2 7.3 8.4 4.1 6.9 2.1 2.5 3.6 2.0 16.0 21.1 2.7 3.3 3.3 10.8 20.8 3.1 7.9 2.1 0.6 3.2 21.1 17.4 5.9 7.0 0.0 14.2 5.9 11.7 3.5 19.1 4.3 0.8 8.7 14.6 0.1 2.0 4.5 3.6 0.6 5.8 7.2 9.7 0.0 0.0 0.4 4.9 15.3 6.6 4.0 13.7 22.8 17.4 4.5 15.6 1.8 0.4 0.0 7.6 11.0 1.9 6.6 7.0 1.4 8.8 0.0 3.9 1.6 1.2 20.8 0.3 2.6 0.4 1.9 0.2 0.4 1.1 2.3 0.5 0.6 3.5 1.6 1.9 23.8 0.0 0.7 13.2 14.5 8.6 15.2 13.9 11.4 13.3 13.8 12.2 9.7 19.3 18.4 1.0 6.4 54.8 105.1 5.0 15.2 3.8 5.0 10.2 7.0 3.7 4.2 79.0 4.3 8.7 16.5 0.0 0.7 24.6 53.8 25.4 5.0 51.0 18.0 3.7 4.2 6.0 0.8 14.5 7.6 0.4 4.6 14.8 21.3 9.5 2.3 2.5 5.8 5.6 3.3 13.0 20.1 8.2 13.6 4.9 158.2 2.8 8.5 21.4 11.2 5.4 9.8 5.2 4.5 10.6 16.6 26.2 3.0 3.8 13.5 45.4 32.8 15.3 110.5 0.0 3.3 3.1 5.1 3.2 9.9 11.6 1.5 1.6 7.5 36.9 11.5 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 334.6;skeletal muscle: 621.3" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Collecting duct cells: 195.0;Langerhans cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 296.2;RPTEC TERT1: 181.8;T-47d: 192.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 334.6 22.7 66.1 72.2 81.2 246.0 153.8 75.4 66.6 30.2 22.1 22.2 19.4 24.0 11.1 51.3 37.7 59.9 21.9 62.8 105.8 243.9 32.8 67.7 24.5 145.7 100.9 24.2 21.0 10.1 39.6 20.0 100.9 20.2 8.9 31.5 40.4 49.5 621.3 53.6 22.9 16.9 90.1 50.2 26.1 13.9 91.8 15.1 10.9 30.4 28.2 63.9 40.3 105.6 22.0 296.2 23.1 18.8 85.2 10.5 12.2 31.6 22.5 22.9 35.5 14.1 78.0 37.2 20.2 13.8 18.0 69.0 24.9 50.2 26.3 44.6 17.3 22.1 16.2 5.2 7.2 21.6 32.2 7.6 16.4 39.5 9.5 58.3 44.9 25.6 16.6 13.6 18.6 35.7 15.3 20.3 22.5 31.1 20.5 34.3 11.3 14.7 181.8 11.1 21.9 8.9 22.9 24.7 45.8 39.5 192.0 25.2 57.0 23.9 22.0 3.1 38.7 27.8 10.4 33.7 65.8 25.0 37.4 2.9 7.5 7.7 2.2 9.2 5.7 1.8 4.2 2.9 4.7 1.6 3.0 3.0 26.4 1.2 5.5 2.9 4.3 4.3 66.1 81.2 75.4 66.6 62.8 105.8 145.7 100.9 100.9 90.1 91.8 105.6 37.1 76.9 55.1 153.8 27.2 102.6 16.7 21.5 37.5 6.4 37.1 36.8 19.5 22.8 32.1 195.0 52.1 0.4 37.0 14.9 0.0 54.7 5.0 41.1 18.9 32.9 8.5 1.3 42.8 25.7 6.9 30.8 33.1 64.3 44.2 72.5 8.9 15.8 20.6 6.7 19.4 6.6 18.3 88.0 132.3 9.5 2.8 122.2 46.2 41.2 19.6 0.3 4.1 14.1 31.9 59.6 5.2 7.2 25.3 4.2 5.4 2.4 19.2 1.9 0.0 58.5 24.4 0.6 2.5 20.9 63.9 1.0 61.7 12.4 8.1 14.7 PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 40.3;Proximal enterocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;eosinophil: 21.9;intermediate monocyte: 13.8;neutrophil: 40.4;non-classical monocyte: 25.1" "Group enriched" "Detected in many" 6 "granulocytes: 40.4;monocytes: 25.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 52.5;U-87 MG: 83.9;WM-115: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli "HPA047719: AB_2680129, HPA066058: AB_2685606" "unprognostic (7.60e-2)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" 1.8 2.5 5.1 4.0 5.5 14.8 1.9 6.1 6.3 3.3 3.4 3.3 18.4 2.0 18.0 7.3 1.6 1.6 1.5 5.1 6.5 3.5 1.7 4.2 1.5 6.8 6.4 3.3 11.2 3.2 5.2 10.2 6.9 3.6 3.4 16.1 2.7 1.3 5.4 3.8 20.8 2.4 5.9 10.3 1.3 24.0 7.7 1.3 1.6 3.4 1.1 2.0 5.8 6.7 12.0 3.9 8.3 8.1 2.8 4.0 16.6 6.1 10.4 11.9 29.3 6.0 4.2 5.5 5.8 4.6 28.4 3.5 3.6 10.6 10.6 3.5 2.9 12.3 9.3 6.7 2.5 2.3 5.1 4.2 15.6 19.4 1.9 52.5 2.9 6.7 4.4 4.5 9.7 2.8 0.8 17.3 5.0 2.3 8.0 0.9 4.1 5.9 4.5 11.4 2.5 5.4 6.6 3.0 23.6 8.2 6.3 5.3 0.9 12.0 4.7 1.6 36.7 21.6 4.4 3.2 83.9 4.3 74.8 0.0 12.5 21.9 0.4 13.8 0.1 0.3 0.6 0.1 5.1 0.2 1.0 0.3 40.4 0.5 25.1 0.6 0.0 4.9 5.1 5.5 6.1 6.3 5.1 6.5 6.8 6.4 6.9 5.9 7.7 6.7 0.1 0.0 1.3 13.1 0.3 3.2 0.3 7.0 1.8 6.3 1.6 1.3 1.0 2.8 2.1 0.0 2.1 13.8 0.2 1.3 0.0 2.9 2.8 1.9 2.4 0.8 4.2 0.4 4.5 1.5 40.3 1.2 0.5 3.3 1.3 2.0 1.1 1.0 6.0 6.7 7.3 13.0 2.0 7.8 0.5 2.6 0.9 7.3 1.8 3.7 3.5 3.3 1.0 6.0 13.9 2.9 1.4 0.7 1.8 0.4 43.6 0.2 2.7 4.4 0.0 0.1 1.5 0.5 0.8 2.5 1.7 5.5 0.9 1.3 3.7 0.1 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8849325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "basophil: 210.5" "Lineage enriched" "Detected in all" 13 "granulocytes: 210.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040852, HPA063649" Approved Approved Nucleoplasm,Cytosol NA NA 21000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA040852: AB_10794069, HPA063649: AB_2685074" "unprognostic (8.62e-3)" "unprognostic (8.00e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.98e-2)" "unprognostic (6.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (5.14e-3)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (6.89e-2)" "unprognostic (5.02e-2)" 18.5 18.3 3.3 15.1 4.6 6.4 16.7 3.3 4.2 13.7 8.4 26.0 25.0 10.6 11.9 29.0 10.7 10.6 13.2 3.8 3.5 16.7 51.8 13.8 13.7 3.6 3.7 7.5 36.5 10.2 12.1 15.5 3.5 14.2 26.0 1.5 22.6 7.4 9.7 16.2 21.3 12.5 3.5 14.0 19.6 4.5 3.9 9.6 11.3 5.9 14.2 21.7 15.7 3.6 26.1 56.5 12.3 32.7 21.8 33.7 27.4 39.8 47.3 38.8 41.6 42.5 31.5 41.0 16.3 69.4 20.2 35.1 25.3 48.5 39.2 30.7 29.0 13.6 33.0 73.8 40.4 36.9 31.6 50.4 33.7 41.1 37.9 18.1 40.1 24.5 18.9 39.6 26.0 68.3 37.9 33.9 52.8 60.0 35.8 47.2 27.4 82.8 43.5 45.0 23.5 43.7 32.7 71.4 23.9 19.5 46.4 31.7 47.7 27.8 31.5 76.6 39.5 48.2 43.3 51.5 23.4 45.5 38.0 210.5 16.5 3.2 7.9 13.0 11.7 9.5 7.0 10.2 12.1 7.8 7.7 7.5 26.5 6.2 8.4 10.9 5.7 10.9 3.3 4.6 3.3 4.2 3.8 3.5 3.6 3.7 3.5 3.5 3.9 3.6 16.5 16.0 24.1 12.7 18.4 3.8 11.6 7.7 14.8 4.7 10.6 9.5 3.1 4.3 28.8 0.0 14.6 8.9 11.9 11.2 9.8 16.3 0.9 15.9 32.0 11.7 7.7 9.0 29.3 28.5 11.9 16.6 23.9 38.5 22.8 12.9 2.5 12.8 5.5 1.7 26.1 21.2 2.0 4.7 1.7 0.9 6.2 10.4 1.8 21.5 9.6 2.5 9.2 22.6 21.6 23.3 9.7 2.2 49.5 12.6 12.3 17.4 16.8 9.0 0.0 13.5 9.8 2.0 4.2 27.0 4.1 10.7 16.0 13.1 12.6 14.9 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689538-49721529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 156.1;tongue: 112.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Supported Approved Cytosol NA NA 140000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA065983: AB_2685592, HPA071879: AB_2686468" "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favorable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 13.0 19.0 18.9 9.0 19.2 34.6 12.5 18.5 23.9 13.1 21.0 17.8 19.5 14.7 10.5 13.4 12.5 9.7 27.8 19.6 16.5 22.0 57.7 12.3 10.4 17.5 16.9 11.6 13.5 16.3 17.4 9.4 17.2 14.6 6.8 6.0 14.4 9.2 156.1 14.5 18.2 9.3 14.7 17.9 17.9 23.7 18.0 13.7 14.6 112.0 7.3 14.2 12.0 17.9 9.7 12.6 15.5 16.2 23.2 13.9 17.1 12.1 15.9 15.0 16.0 14.1 16.1 23.2 10.9 17.6 13.3 11.8 11.6 18.1 10.0 15.8 15.0 19.7 27.8 31.6 23.1 19.3 19.8 17.6 17.9 14.4 16.5 14.8 16.2 23.0 20.0 20.0 13.2 14.1 19.8 30.7 8.2 11.5 21.0 9.3 9.7 24.4 21.5 16.4 10.6 20.8 16.4 14.4 18.7 8.7 15.4 33.0 16.2 13.4 16.3 11.9 14.9 26.4 28.4 9.5 19.2 23.6 20.5 8.9 6.9 5.6 6.7 6.2 4.0 7.1 4.5 4.1 5.5 7.0 5.3 5.0 4.0 5.5 6.8 7.9 3.6 3.8 18.9 19.2 18.5 23.9 19.6 16.5 17.5 16.9 17.2 14.7 18.0 17.9 7.1 9.6 5.3 16.3 6.5 2.3 3.1 4.7 1.8 8.6 7.1 6.1 1.1 11.5 5.8 3.7 4.2 6.8 9.3 10.4 5.9 5.3 13.3 8.1 5.8 5.9 6.7 52.4 18.0 5.5 4.6 5.9 11.2 7.5 7.0 9.5 10.0 29.8 5.6 6.7 14.6 6.1 10.2 9.6 1.4 16.5 7.5 6.0 3.6 5.6 6.3 5.4 7.2 7.5 7.2 7.2 6.3 5.7 7.0 5.0 19.2 10.2 5.4 8.9 0.0 7.6 5.6 10.7 8.9 4.6 3.0 8.5 6.0 7.5 6.9 4.1 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4360028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB034010: AB_1128227, HPA040354: AB_2676935, HPA044111: AB_2678814" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 3.8 5.4 1.4 1.9 1.6 1.9 2.9 1.9 3.0 1.8 1.8 3.7 0.7 2.8 1.2 3.7 2.3 1.4 5.0 2.2 1.6 4.2 3.1 3.7 2.0 1.9 2.0 1.1 2.0 0.9 5.3 1.4 2.1 2.8 1.7 2.3 3.0 1.7 5.8 2.5 3.6 2.1 2.1 5.3 3.3 3.5 1.9 1.7 2.3 2.0 1.9 3.5 2.4 2.3 4.1 9.9 4.8 7.7 10.9 6.3 47.3 9.3 8.0 5.3 7.3 5.7 3.8 4.1 0.7 5.8 5.2 5.7 5.8 7.6 7.0 3.8 2.9 0.1 4.7 7.8 14.3 2.1 0.5 8.1 12.9 5.9 6.8 3.2 14.5 3.4 0.3 2.2 9.2 7.7 2.2 0.8 8.6 5.5 1.7 3.0 6.4 1.0 6.7 5.0 0.2 2.8 7.9 3.2 10.1 22.0 0.8 1.6 10.5 8.2 5.9 5.6 3.8 1.4 2.1 6.9 5.4 0.8 5.7 0.5 1.7 0.2 0.7 3.5 0.5 0.9 0.7 0.8 1.9 1.3 0.6 0.7 1.5 0.8 3.4 1.6 1.4 0.6 1.4 1.6 1.9 3.0 2.2 1.6 1.9 2.0 2.1 2.1 1.9 2.3 10.7 0.0 1.7 0.0 14.7 0.0 13.8 0.0 5.7 4.2 6.2 7.5 10.5 1.5 0.0 5.5 18.8 27.4 16.9 5.0 15.6 15.6 28.0 4.7 5.9 9.4 7.3 1.3 0.0 13.9 28.5 6.6 11.7 4.8 0.0 4.5 5.0 5.6 59.3 1.7 0.0 1.5 0.0 20.4 0.0 27.8 3.7 30.6 0.0 0.0 34.9 11.5 7.2 0.0 0.0 17.5 2.6 4.5 16.3 9.5 2.9 11.7 0.0 3.3 6.6 5.7 8.3 19.9 22.3 8.1 0.0 34.3 11.8 10.8 2.3 15.6 TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235387-74544428 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 58.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.0;Early spermatids: 32.0;Late spermatids: 6.6;Proximal tubular cells: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.0" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (3.83e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-1)" "unprognostic (3.40e-2)" "unprognostic (3.05e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-1)" "unprognostic (9.66e-2)" "unprognostic (5.04e-2)" "unprognostic (1.80e-1)" "unprognostic (3.59e-3)" "unprognostic (4.88e-3)" "unprognostic (1.20e-1)" "unprognostic (8.80e-2)" "unprognostic (8.77e-2)" 1.8 1.4 3.6 0.3 3.6 0.1 1.4 4.9 7.2 1.0 2.0 2.0 0.4 1.3 2.5 0.6 1.5 0.4 58.7 3.7 3.9 3.4 0.4 0.9 0.4 3.3 3.2 1.5 0.4 0.7 2.3 0.0 3.6 1.1 0.5 5.2 0.8 0.4 1.5 1.6 0.8 0.9 3.5 1.4 1.1 4.0 3.5 0.4 1.0 0.6 0.5 1.4 0.9 4.8 0.0 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.6 3.6 4.9 7.2 3.7 3.9 3.3 3.2 3.6 3.5 3.5 4.8 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 1.2 0.2 0.3 27.0 0.0 0.1 1.8 0.0 0.0 0.0 0.1 1.9 0.1 32.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 8.0 0.1 0.5 0.0 0.6 0.8 0.5 1.4 0.0 0.3 0.1 0.1 0.0 0.0 0.2