Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
BCO2	"B-DIOX-II, BCDO2, FLJ34464"	ENSG00000197580	"Beta-carotene oxygenase 2"	Q9BYV7	11	112175510-112224699	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Dioxygenase, Oxidoreductase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 47.2;liver: 52.3;retina: 55.9"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6"	"Low cancer specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA061542	Supported					NA	NA			"Cluster 22: NK-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 9: Photoreceptor cells - Phototransduction"			"HPA061542: "	"unprognostic (2.92e-1)"	"unprognostic (1.89e-1)"	"unprognostic (3.76e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.91e-1)"	"unprognostic (1.50e-2)"	"unprognostic (7.60e-3)"	"unprognostic (1.88e-1)"	"unprognostic (3.18e-2)"	"unprognostic (6.40e-2)"	"unprognostic (2.39e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.36e-4)"	"unprognostic (2.31e-2)"	"unprognostic (9.86e-2)"	"unprognostic (1.07e-2)"	"unprognostic (1.34e-1)"	3.8	21.3	4.9	0.3	5.8	0.2	0.8	5.0	9.3	2.2	10.0	2.6	0.5	1.6	1.0	3.4	9.7	5.1	47.2	4.8	6.4	2.5	52.3	1.7	0.4	7.4	6.7	1.3	1.1	0.3	4.4	3.8	7.0	1.9	0.5	55.9	0.9	0.9	21.4	1.1	1.7	1.1	5.9	1.1	0.9	3.0	6.5	0.3	2.5	14.3	0.8	2.3	4.6	8.3	0.1	1.0	0.4	0.6	0.4	0.4	0.0	0.3	0.2	0.1	0.5	0.0	5.9	0.4	0.5	0.6	0.6	1.2	0.0	0.2	0.4	0.1	0.1	0.7	0.5	0.4	12.3	0.4	0.2	0.1	2.3	0.1	0.3	1.1	0.0	0.1	0.1	0.3	0.1	0.0	0.5	1.3	0.1	0.6	0.2	0.3	0.1	0.2	0.2	0.2	0.5	0.2	0.4	0.2	0.0	0.1	0.3	0.2	0.0	0.1	0.2	0.1	0.1	0.1	0.0	0.3	0.0	2.6	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.1	0.0	0.0	0.0	4.9	5.8	5.0	9.3	4.8	6.4	7.4	6.7	7.0	5.9	6.5	8.3	1.7	3.2	3.1	10.1	2.0	3.3	20.3	8.6	6.8	12.6	2.2	1.5	51.3	58.6	8.2	5.5	410.8	0.3	4.4	5.0	0.0	3.7	3.1	26.5	3.0	4.5	8.3	0.0	50.7	2.1	0.4	16.3	1.1	1.2	5.7	4.0	16.4	83.1	1.0	134.6	51.5	1.6	2.0	2.8	3.8	2.4	4.1	7.9	1.8	47.8	3.7	13.9	7.2	7.1	51.3	1.6	2.6	3.8	1.2	10.3	18.2	1.3	67.6	254.6	0.0	5.0	3.8	8.3	2.5	1.8	3.1	0.7	5.2	6.8	3.5	8.7
CYP11B1	"CPN1, CYP11B, FHI, P450C11"	ENSG00000160882	"Cytochrome P450 family 11 subfamily B member 1"	P15538	8	142872356-142879846	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis"	"Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	877	"adrenal gland: 3686.5"	"Group enriched"	"Detected in some"	113	"Early spermatids: 53.3;Late spermatids: 83.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA049171, HPA049565, HPA056348, HPA057752"	Supported		Approved	Mitochondria		NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"		"Cluster 25: Spermatids - Spermatogenesis"	Mitochondria		"HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516"																		0.2	3686.5	0.1	0.9	0.6	0.0	0.1	0.0	0.1	0.2	0.5	0.2	0.0	0.2	0.0	0.4	0.2	0.0	0.4	0.3	0.0	0.9	0.5	0.3	0.0	0.1	0.1	0.3	0.5	0.0	0.4	0.0	0.0	0.3	0.0	0.0	1.4	0.0	0.2	0.2	0.2	0.0	0.0	0.3	0.4	4.2	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.0	0.1	0.3	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	53.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	83.4	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0
CYP11B2	"ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo"	ENSG00000179142	"Cytochrome P450 family 11 subfamily B member 2"	P19099	8	142910559-142917843	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism, Steroidogenesis"	"Monooxygenase, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	603	"adrenal gland: 179.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											"HPA049171, HPA049565, HPA056348, HPA057752"	Supported		Uncertain	Mitochondria		NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"		"Cluster 43: Cardiomyocytes - Nuclear processes"	Mitochondria		"HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516"																		0.0	179.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
CYP17A1	"CPT7, CYP17, P450C17, S17AH"	ENSG00000148795	"Cytochrome P450 family 17 subfamily A member 1"	P05093	10	102830531-102837472	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Steroidogenesis	"Lyase, Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	84	"adrenal gland: 8229.5"	"Cell type enriched"	"Detected in some"	17	"Theca cells: 1871.0"	"Cancer enriched"	"Detected in many"	5	"liver cancer: 22.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HMC-1: 3.0;SCLC-21H: 1.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA048533	Enhanced		Approved	Vesicles	"Intracellular and membrane"	NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 52: Non-specific - Transcription"	Vesicles		"HPA048533: AB_2680432"	"unprognostic (1.07e-2)"	"unprognostic (8.84e-2)"	"unprognostic (3.01e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.91e-1)"	"unprognostic (6.29e-2)"	"unprognostic (2.92e-3)"	"unprognostic (2.39e-4)"	"unprognostic (8.26e-2)"	"unprognostic (2.35e-1)"	"unprognostic (5.92e-3)"	"unprognostic (1.13e-1)"	"prognostic favorable (5.43e-7)"	"unprognostic (1.07e-1)"	"unprognostic (5.56e-2)"	"unprognostic (1.66e-2)"	"unprognostic (2.94e-4)"	0.4	8229.5	0.0	2.1	0.0	0.0	0.4	0.1	0.1	1.1	0.0	0.5	0.0	0.8	0.1	0.9	1.0	0.4	1.0	0.0	0.0	52.9	6.7	1.4	0.0	0.0	0.1	16.6	1.7	10.5	0.7	0.0	0.0	0.7	0.0	0.2	3.4	0.0	1.0	0.7	0.6	0.0	0.0	0.9	1.3	98.3	0.0	0.0	2.9	0.0	0.0	0.8	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	2.2	0.1	0.4	0.1	0.0	0.5	0.0	0.1	0.7	0.0	0.0	1.8	0.0	0.4	0.1	0.1	21.5	0.0	41.6	0.1	0.0	0.7	0.0	2.7	0.1	0.2	0.0	1.3	0.0	0.1	0.0	0.1	0.4	6.1	0.1	1.7	0.1	0.0	0.0	0.6	0.7	10.6	1.8	0.9	0.0	0.0	0.1	0.2	3.1	0.5	0.1	0.7	0.0	0.0	0.0	0.3	0.0	104.3	0.0	1.2	0.0	1.2	0.6	0.3	0.1	0.0	0.0	0.3	0.4	1871.0	0.0	0.1
CYP21A2	"CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B"	ENSG00000231852	"Cytochrome P450 family 21 subfamily A member 2"	P08686	6	32038327-32041644	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Steroidogenesis	"Monooxygenase, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	46	"adrenal gland: 2041.7"	"Cell type enriched"	"Detected in some"	6	"Hepatocytes: 15.9"	"Cancer enhanced"	"Detected in some"		"liver cancer: 2.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"HDLM-2: 3.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA048979, HPA053371"	Enhanced					NA	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 15: Hepatocytes - Hemostasis"			"HPA048979: AB_2680584, HPA053371: AB_2682131"	"unprognostic (1.03e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.02e-4)"	"unprognostic (2.58e-1)"	"unprognostic (2.97e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.76e-2)"	"unprognostic (8.75e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.93e-1)"	"unprognostic (6.67e-7)"	"unprognostic (7.39e-2)"	"unprognostic (5.24e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.82e-1)"	2.0	2041.7	0.0	0.0	0.0	0.0	1.5	0.0	0.6	1.9	0.0	2.5	0.0	1.5	0.6	0.6	2.4	0.0	2.9	0.0	0.0	7.0	44.8	0.8	0.0	0.0	0.0	4.3	0.9	0.0	1.9	0.0	0.0	1.9	0.0	0.0	4.0	0.0	0.3	0.7	1.1	0.0	0.0	5.5	0.8	0.8	0.0	0.0	2.3	0.0	0.0	2.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.3	0.1	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.1	0.2	0.0	0.4	2.4	0.5	0.3	1.5	0.8	0.0	0.0	0.0	0.4	0.0	0.0	0.2	0.1	0.1	0.8	0.9	1.8	0.0	0.1	0.0	0.0	1.6	0.0	0.2	1.3	0.4	0.0	15.9	0.0	0.0	0.1	0.0	0.0	0.3	0.3	0.1	0.6	0.1	1.8	0.0	0.0	0.3	0.0	0.0	0.1	0.3	0.0	0.0	0.0	0.2	0.0	2.0	1.2	0.6	0.0	0.3	0.6	0.6	0.4	0.0	0.0	0.0	0.3	1.0	0.0	0.0
HSD11B1	"HSD11, HSD11B, SDR26C1"	ENSG00000117594	"Hydroxysteroid 11-beta dehydrogenase 1"	P28845	1	209686178-209734949	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Steroid metabolism"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	13	"liver: 968.3"	"Cell type enriched"	"Detected in many"	9	"Hepatocytes: 646.2"	"Cancer enriched"	"Detected in all"	28	"liver cancer: 197.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"memory CD4 T-cell: 5.6"	"Lineage enriched"	"Detected in single"	17	"T-cells: 5.6"	"Cell line enriched"	"Detected in some"	5	"ASC diff: 989.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA047729	Enhanced					NA	NA		110000	"Cluster 35: T-regs - Unknown function"	"Cluster 60: Liver - Hemostasis & Lipid metabolism"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 2: Hepatocytes - Metabolism"			"HPA047729: AB_2680135"	"unprognostic (1.08e-3)"	"unprognostic (2.13e-1)"	"unprognostic (2.32e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.57e-1)"	"unprognostic (3.68e-1)"	"unprognostic (2.02e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.30e-1)"	"unprognostic (3.63e-2)"	"unprognostic (8.35e-3)"	"unprognostic (8.69e-2)"	"prognostic unfavorable (1.97e-10)"	"unprognostic (3.41e-2)"	"unprognostic (3.91e-2)"	"unprognostic (6.45e-2)"	"unprognostic (1.59e-2)"	22.4	7.7	9.8	14.6	15.4	0.3	12.0	23.0	22.0	2.8	8.1	4.2	1.2	4.2	15.7	2.1	5.1	8.0	7.5	11.0	16.0	24.3	968.3	39.9	4.3	14.3	21.4	59.9	3.2	0.2	8.8	72.5	16.3	27.8	3.3	0.6	2.5	13.0	5.5	33.8	5.0	12.9	9.4	7.3	7.1	7.2	12.8	0.6	5.2	10.6	1.9	27.9	6.3	17.5	0.4	0.0	0.0	0.0	989.2	102.8	0.0	0.1	36.0	0.0	0.1	0.0	0.2	0.0	0.2	0.3	0.1	0.1	0.0	43.9	0.0	0.0	0.0	0.0	0.0	0.0	206.6	0.2	0.1	5.4	0.0	6.9	0.4	0.9	0.0	0.0	0.0	51.2	0.2	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.7	16.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	34.9	8.4	4.0	0.2	0.2	0.3	1.4	0.3	0.3	5.7	1.4	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.1	5.6	1.2	0.0	0.0	0.1	0.0	0.1	0.3	0.0	0.0	1.7	0.4	9.8	15.4	23.0	22.0	11.0	16.0	14.3	21.4	16.3	9.4	12.8	17.5	0.4	3.2	0.0	1.3	0.8	0.1	0.4	4.8	0.6	0.5	0.2	0.0	1.4	30.0	1.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	5.2	0.9	0.6	1.0	0.0	5.3	3.3	0.0	0.1	66.4	0.5	2.8	0.0	0.0	7.5	646.2	8.3	0.0	2.8	0.0	0.0	7.9	2.3	2.8	29.2	3.7	0.0	28.1	0.6	16.2	0.0	0.5	55.7	0.4	0.0	7.9	0.0	0.9	0.0	0.2	0.1	0.5	0.0	2.6	5.5	0.0	0.2	0.1	0.1	0.3	1.1	0.3	0.0	1.7
HSD3B1	"HSD3B, HSDB3, SDR11E1"	ENSG00000203857	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1"	P14060	1	119507198-119515054	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid metabolism, Steroid metabolism, Steroidogenesis"	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	9	"placenta: 77.7"	"Group enriched"	"Detected in some"	8	"Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0"	"Cancer enriched"	"Detected in single"	4	"urothelial cancer: 1.6"	"Region enhanced"	"Detected in some"		"basal ganglia: 1.0;cerebral cortex: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	6	"CACO-2: 64.1;SuSa: 26.5"									"HPA043261, HPA043264, HPA044028"	Supported		Approved	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 28: Placenta - Pregnancy"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"			"unprognostic (1.53e-1)"				"unprognostic (7.11e-2)"					"unprognostic (1.15e-1)"		"unprognostic (1.04e-1)"			"prognostic favorable (4.59e-5)"	0.1	1.2	0.2	0.0	1.0	0.0	1.5	0.0	1.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.3	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	77.7	0.0	0.1	0.5	0.0	0.1	0.0	0.1	4.5	8.7	0.5	0.0	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.7	0.2	0.0	0.0	0.0	64.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.8	0.0	0.0	0.0	0.0	0.0	3.9	0.0	0.0	7.0	0.7	0.8	26.5	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	1.0	0.0	1.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	23.6	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	0.0	140.8	0.8	0.0	0.0	0.0	0.0	0.0	0.0	7.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.0	37.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	502.0	0.0	0.1	1.0	0.0
HSD3B2	SDR11E2	ENSG00000203859	"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2"	P26439	1	119414931-119423035	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	Steroidogenesis	"Isomerase, Multifunctional enzyme, Oxidoreductase"	"Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	56	"adrenal gland: 2174.8"	"Group enriched"	"Detected in some"	4	"Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9"	"Cancer enhanced"	"Detected in single"		"testis cancer: 0.6"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"SK-MEL-30: 1.4"									"HPA043261, HPA043264, HPA044028"	Supported		Uncertain	"Nucleoli,Endoplasmic reticulum,Cytokinetic bridge"		Yes	NA				"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 52: Non-specific - Transcription"	"Nucleoli, Endoplasmic reticulum"	"Cytokinetic bridge"	"HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781"	"unprognostic (3.56e-1)"		"unprognostic (1.85e-1)"		"unprognostic (2.80e-1)"		"unprognostic (2.72e-2)"		"unprognostic (8.87e-2)"	"unprognostic (3.91e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.94e-1)"	"unprognostic (6.51e-2)"	"unprognostic (1.97e-2)"	"unprognostic (1.55e-1)"			0.2	2174.8	0.3	2.1	0.8	0.0	0.1	0.0	0.7	0.2	0.0	7.7	0.0	0.2	0.0	0.2	0.4	0.0	0.3	0.2	0.0	0.9	1.0	0.5	0.0	0.0	0.0	0.9	0.5	0.0	0.1	3.6	0.1	0.4	1.0	0.0	1.0	0.0	0.1	0.2	38.7	0.1	0.0	0.2	0.3	2.9	0.2	0.5	0.2	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.4	0.0	0.0	1.4	0.5	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.8	0.0	0.7	0.2	0.0	0.0	0.0	0.1	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	11.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.1	3.5	0.0	0.0	0.0	40.6	0.0	0.0	0.1	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	2.6	0.0	0.0	38.8	0.4	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	68.9	1.7	0.0