[{"Gene":"GNS","Gene synonym":[],"Ensembl":"ENSG00000135677","Gene description":"Glucosamine (N-acetyl)-6-sulfatase","Uniprot":["P15586"],"Chromosome":"12","Position":"64713445-64759431","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"198.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"228.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013695","CAB026011","HPA048508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026011":null,"HPA013695":"AB_1849741","HPA048508":"AB_2680423"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"106.1","Tissue RNA - adrenal gland [nTPM]":"174.7","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"56.4","Tissue RNA - basal ganglia [nTPM]":"19.9","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"51.9","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"58.9","Tissue RNA - choroid plexus [nTPM]":"80.7","Tissue RNA - colon [nTPM]":"35.3","Tissue RNA - duodenum [nTPM]":"34.6","Tissue RNA - endometrium 1 [nTPM]":"49.5","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"43.8","Tissue RNA - gallbladder [nTPM]":"63.7","Tissue RNA - heart muscle [nTPM]":"52.9","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"26.4","Tissue RNA - kidney [nTPM]":"132.0","Tissue RNA - liver [nTPM]":"56.2","Tissue RNA - lung [nTPM]":"71.5","Tissue RNA - lymph node [nTPM]":"41.0","Tissue RNA - medulla oblongata [nTPM]":"30.0","Tissue RNA - midbrain [nTPM]":"23.3","Tissue RNA - ovary [nTPM]":"64.3","Tissue RNA - pancreas [nTPM]":"24.1","Tissue RNA - parathyroid gland [nTPM]":"76.8","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"80.2","Tissue RNA - pons [nTPM]":"25.5","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"36.9","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"47.7","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"26.3","Tissue RNA - small intestine [nTPM]":"41.4","Tissue RNA - smooth muscle [nTPM]":"69.2","Tissue RNA - spinal cord [nTPM]":"22.5","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"34.6","Tissue RNA - testis [nTPM]":"31.8","Tissue RNA - thalamus [nTPM]":"27.3","Tissue RNA - thymus [nTPM]":"20.5","Tissue RNA - thyroid gland [nTPM]":"72.8","Tissue RNA - tongue [nTPM]":"29.0","Tissue RNA - tonsil [nTPM]":"26.9","Tissue RNA - urinary bladder [nTPM]":"63.7","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"31.2","Cell RNA - A-431 [nTPM]":"41.0","Cell RNA - A549 [nTPM]":"61.3","Cell RNA - AF22 [nTPM]":"50.7","Cell RNA - AN3-CA [nTPM]":"81.4","Cell RNA - ASC diff [nTPM]":"240.0","Cell RNA - ASC TERT1 [nTPM]":"145.2","Cell RNA - BEWO [nTPM]":"108.8","Cell RNA - BJ [nTPM]":"92.0","Cell RNA - BJ hTERT+ [nTPM]":"213.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.1","Cell RNA - CACO-2 [nTPM]":"55.9","Cell RNA - CAPAN-2 [nTPM]":"53.3","Cell RNA - Daudi [nTPM]":"17.4","Cell RNA - EFO-21 [nTPM]":"117.0","Cell RNA - fHDF\/TERT166 [nTPM]":"117.8","Cell RNA - GAMG [nTPM]":"133.3","Cell RNA - HaCaT [nTPM]":"33.1","Cell RNA - HAP1 [nTPM]":"49.1","Cell RNA - HBEC3-KT [nTPM]":"52.6","Cell RNA - HBF TERT88 [nTPM]":"119.5","Cell RNA - HDLM-2 [nTPM]":"51.4","Cell RNA - HEK 293 [nTPM]":"36.6","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"45.4","Cell RNA - Hep G2 [nTPM]":"36.4","Cell RNA - HHSteC [nTPM]":"109.3","Cell RNA - HL-60 [nTPM]":"30.6","Cell RNA - HMC-1 [nTPM]":"346.2","Cell RNA - HSkMC [nTPM]":"139.6","Cell RNA - hTCEpi [nTPM]":"62.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.5","Cell RNA - hTERT-HME1 [nTPM]":"49.3","Cell RNA - hTERT-RPE1 [nTPM]":"342.0","Cell RNA - HUVEC TERT2 [nTPM]":"200.1","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"28.8","Cell RNA - Karpas-707 [nTPM]":"117.2","Cell RNA - LHCN-M2 [nTPM]":"156.8","Cell RNA - MCF7 [nTPM]":"32.6","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"102.8","Cell RNA - PC-3 [nTPM]":"53.2","Cell RNA - REH [nTPM]":"23.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"53.7","Cell RNA - RPTEC TERT1 [nTPM]":"91.5","Cell RNA - RT4 [nTPM]":"116.2","Cell RNA - SCLC-21H [nTPM]":"33.7","Cell RNA - SH-SY5Y [nTPM]":"37.3","Cell RNA - SiHa [nTPM]":"119.6","Cell RNA - SK-BR-3 [nTPM]":"56.6","Cell RNA - SK-MEL-30 [nTPM]":"82.4","Cell RNA - SuSa [nTPM]":"65.8","Cell RNA - T-47d [nTPM]":"102.2","Cell RNA - THP-1 [nTPM]":"40.4","Cell RNA - TIME [nTPM]":"185.1","Cell RNA - U-138 MG [nTPM]":"104.5","Cell RNA - U-2 OS [nTPM]":"54.8","Cell RNA - U-2197 [nTPM]":"101.8","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"112.1","Cell RNA - U-266\/84 [nTPM]":"143.4","Cell RNA - U-698 [nTPM]":"14.9","Cell RNA - U-87 MG [nTPM]":"151.1","Cell RNA - U-937 [nTPM]":"58.4","Cell RNA - WM-115 [nTPM]":"72.1","Blood RNA - basophil [nTPM]":"51.7","Blood RNA - classical monocyte [nTPM]":"136.9","Blood RNA - eosinophil [nTPM]":"27.5","Blood RNA - gdT-cell [nTPM]":"29.3","Blood RNA - intermediate monocyte [nTPM]":"158.4","Blood RNA - MAIT T-cell [nTPM]":"21.9","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.9","Blood RNA - memory CD8 T-cell [nTPM]":"22.6","Blood RNA - myeloid DC [nTPM]":"78.2","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"16.4","Blood RNA - neutrophil [nTPM]":"56.6","Blood RNA - NK-cell [nTPM]":"18.4","Blood RNA - non-classical monocyte [nTPM]":"228.5","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"101.9","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.9","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"26.4","Brain RNA - medulla oblongata [nTPM]":"30.0","Brain RNA - midbrain [nTPM]":"23.3","Brain RNA - pons [nTPM]":"25.5","Brain RNA - spinal cord [nTPM]":"22.5","Brain RNA - thalamus [nTPM]":"27.3","Brain RNA - white matter [nTPM]":"31.2","Single Cell Type RNA - Adipocytes [nTPM]":"52.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"24.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"103.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.3","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"36.2","Single Cell Type RNA - Early spermatids [nTPM]":"24.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"50.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"15.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"40.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.9","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"36.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"58.5","Single Cell Type RNA - Hepatocytes [nTPM]":"57.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"81.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"198.8","Single Cell Type RNA - Langerhans cells [nTPM]":"46.5","Single Cell Type RNA - Late spermatids [nTPM]":"24.5","Single Cell Type RNA - Leydig cells [nTPM]":"34.8","Single Cell Type RNA - Macrophages [nTPM]":"107.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"79.0","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.7","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"60.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.1","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"30.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.2","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"GUSB","Gene synonym":[],"Ensembl":"ENSG00000169919","Gene description":"Glucuronidase beta","Uniprot":["P08236"],"Chromosome":"7","Position":"65960684-65982215","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"213.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036322","HPA036323"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036322":"AB_10670796","HPA036323":"AB_2675059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"18.2","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"12.3","Tissue RNA - bone marrow [nTPM]":"84.2","Tissue RNA - breast [nTPM]":"80.9","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"16.1","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"38.2","Tissue RNA - duodenum [nTPM]":"36.1","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"41.8","Tissue RNA - esophagus [nTPM]":"16.4","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"27.6","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"25.1","Tissue RNA - liver [nTPM]":"104.0","Tissue RNA - lung [nTPM]":"35.7","Tissue RNA - lymph node [nTPM]":"25.6","Tissue RNA - medulla oblongata [nTPM]":"13.2","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"19.9","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"30.3","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"48.2","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"41.9","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"21.2","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"29.8","Tissue RNA - smooth muscle [nTPM]":"19.1","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"34.0","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"19.5","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"22.7","Tissue RNA - thyroid gland [nTPM]":"27.7","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"27.3","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"13.5","Cell RNA - A-431 [nTPM]":"67.0","Cell RNA - A549 [nTPM]":"26.5","Cell RNA - AF22 [nTPM]":"25.2","Cell RNA - AN3-CA [nTPM]":"56.3","Cell RNA - ASC diff [nTPM]":"80.9","Cell RNA - ASC TERT1 [nTPM]":"49.1","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"21.3","Cell RNA - BJ hTERT+ [nTPM]":"56.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.1","Cell RNA - CACO-2 [nTPM]":"37.0","Cell RNA - CAPAN-2 [nTPM]":"67.8","Cell RNA - Daudi [nTPM]":"30.9","Cell RNA - EFO-21 [nTPM]":"32.3","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"24.1","Cell RNA - HaCaT [nTPM]":"27.5","Cell RNA - HAP1 [nTPM]":"16.5","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"34.1","Cell RNA - HEL [nTPM]":"41.5","Cell RNA - HeLa [nTPM]":"40.9","Cell RNA - Hep G2 [nTPM]":"27.3","Cell RNA - HHSteC [nTPM]":"39.7","Cell RNA - HL-60 [nTPM]":"89.6","Cell RNA - HMC-1 [nTPM]":"67.1","Cell RNA - HSkMC [nTPM]":"33.4","Cell RNA - hTCEpi [nTPM]":"26.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.3","Cell RNA - hTERT-HME1 [nTPM]":"33.3","Cell RNA - hTERT-RPE1 [nTPM]":"54.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.3","Cell RNA - JURKAT [nTPM]":"18.0","Cell RNA - K-562 [nTPM]":"63.2","Cell RNA - Karpas-707 [nTPM]":"213.5","Cell RNA - LHCN-M2 [nTPM]":"30.5","Cell RNA - MCF7 [nTPM]":"50.3","Cell RNA - MOLT-4 [nTPM]":"34.2","Cell RNA - NB-4 [nTPM]":"92.0","Cell RNA - NTERA-2 [nTPM]":"17.9","Cell RNA - OE19 [nTPM]":"103.0","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"34.4","Cell RNA - RH-30 [nTPM]":"55.9","Cell RNA - RPMI-8226 [nTPM]":"172.4","Cell RNA - RPTEC TERT1 [nTPM]":"29.4","Cell RNA - RT4 [nTPM]":"42.8","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"32.7","Cell RNA - SiHa [nTPM]":"55.6","Cell RNA - SK-BR-3 [nTPM]":"129.1","Cell RNA - SK-MEL-30 [nTPM]":"72.3","Cell RNA - SuSa [nTPM]":"29.9","Cell RNA - T-47d [nTPM]":"71.1","Cell RNA - THP-1 [nTPM]":"88.8","Cell RNA - TIME [nTPM]":"28.5","Cell RNA - U-138 MG [nTPM]":"55.3","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"21.8","Cell RNA - U-251 MG [nTPM]":"53.6","Cell RNA - U-266\/70 [nTPM]":"119.6","Cell RNA - U-266\/84 [nTPM]":"151.9","Cell RNA - U-698 [nTPM]":"50.0","Cell RNA - U-87 MG [nTPM]":"41.0","Cell RNA - U-937 [nTPM]":"116.3","Cell RNA - WM-115 [nTPM]":"68.3","Blood RNA - basophil [nTPM]":"26.0","Blood RNA - classical monocyte [nTPM]":"80.1","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"32.0","Blood RNA - intermediate monocyte [nTPM]":"103.0","Blood RNA - MAIT T-cell [nTPM]":"28.4","Blood RNA - memory B-cell [nTPM]":"27.7","Blood RNA - memory CD4 T-cell [nTPM]":"24.7","Blood RNA - memory CD8 T-cell [nTPM]":"28.4","Blood RNA - myeloid DC [nTPM]":"80.5","Blood RNA - naive B-cell [nTPM]":"22.6","Blood RNA - naive CD4 T-cell [nTPM]":"16.8","Blood RNA - naive CD8 T-cell [nTPM]":"19.5","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"46.6","Blood RNA - non-classical monocyte [nTPM]":"93.5","Blood RNA - plasmacytoid DC [nTPM]":"34.2","Blood RNA - T-reg [nTPM]":"34.5","Blood RNA - total PBMC [nTPM]":"51.4","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.3","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"16.1","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"13.2","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"13.5","Single Cell Type RNA - Adipocytes [nTPM]":"53.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.0","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"48.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"81.9","Single Cell Type RNA - dendritic cells [nTPM]":"32.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"52.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"41.1","Single Cell Type RNA - Early spermatids [nTPM]":"59.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.5","Single Cell Type RNA - Endothelial cells [nTPM]":"39.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.0","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"49.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.4","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"72.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"126.4","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"88.1","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"46.7","Single Cell Type RNA - Leydig cells [nTPM]":"43.2","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"44.8","Single Cell Type RNA - Muller glia cells [nTPM]":"28.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"49.5","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"87.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.0","Single Cell Type RNA - Spermatocytes [nTPM]":"49.6","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.9","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"24.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"44.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.6"},{"Gene":"HEXA","Gene synonym":[],"Ensembl":"ENSG00000213614","Gene description":"Hexosaminidase subunit alpha","Uniprot":["P06865"],"Chromosome":"15","Position":"72340924-72376420","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"234.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018082","HPA054583"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018082":null,"HPA054583":"AB_2682531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"49.8","Tissue RNA - adrenal gland [nTPM]":"56.1","Tissue RNA - amygdala [nTPM]":"18.3","Tissue RNA - appendix [nTPM]":"37.6","Tissue RNA - basal ganglia [nTPM]":"21.1","Tissue RNA - bone marrow [nTPM]":"110.0","Tissue RNA - breast [nTPM]":"58.5","Tissue RNA - cerebellum [nTPM]":"20.4","Tissue RNA - cerebral cortex [nTPM]":"21.6","Tissue RNA - cervix [nTPM]":"73.8","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"55.1","Tissue RNA - duodenum [nTPM]":"49.8","Tissue RNA - endometrium 1 [nTPM]":"42.6","Tissue RNA - epididymis [nTPM]":"164.6","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"47.8","Tissue RNA - gallbladder [nTPM]":"76.7","Tissue RNA - heart muscle [nTPM]":"54.3","Tissue RNA - hippocampal formation [nTPM]":"19.9","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"90.1","Tissue RNA - liver [nTPM]":"79.4","Tissue RNA - lung [nTPM]":"84.2","Tissue RNA - lymph node [nTPM]":"54.2","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"21.3","Tissue RNA - ovary [nTPM]":"39.3","Tissue RNA - pancreas [nTPM]":"30.6","Tissue RNA - parathyroid gland [nTPM]":"54.0","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"102.0","Tissue RNA - pons [nTPM]":"24.6","Tissue RNA - prostate [nTPM]":"45.3","Tissue RNA - rectum [nTPM]":"67.0","Tissue RNA - retina [nTPM]":"32.1","Tissue RNA - salivary gland [nTPM]":"45.0","Tissue RNA - seminal vesicle [nTPM]":"53.3","Tissue RNA - skeletal muscle [nTPM]":"22.1","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"41.2","Tissue RNA - smooth muscle [nTPM]":"59.5","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"54.7","Tissue RNA - stomach 1 [nTPM]":"45.1","Tissue RNA - testis [nTPM]":"35.6","Tissue RNA - thalamus [nTPM]":"27.0","Tissue RNA - thymus [nTPM]":"38.1","Tissue RNA - thyroid gland [nTPM]":"76.5","Tissue RNA - tongue [nTPM]":"33.2","Tissue RNA - tonsil [nTPM]":"42.4","Tissue RNA - urinary bladder [nTPM]":"71.6","Tissue RNA - vagina [nTPM]":"19.7","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"39.8","Cell RNA - A549 [nTPM]":"66.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"53.8","Cell RNA - ASC diff [nTPM]":"223.6","Cell RNA - ASC TERT1 [nTPM]":"253.1","Cell RNA - BEWO [nTPM]":"39.7","Cell RNA - BJ [nTPM]":"54.8","Cell RNA - BJ hTERT+ [nTPM]":"274.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"282.7","Cell RNA - Daudi [nTPM]":"32.9","Cell RNA - EFO-21 [nTPM]":"50.9","Cell RNA - fHDF\/TERT166 [nTPM]":"110.0","Cell RNA - GAMG [nTPM]":"59.9","Cell RNA - HaCaT [nTPM]":"77.1","Cell RNA - HAP1 [nTPM]":"74.5","Cell RNA - HBEC3-KT [nTPM]":"34.6","Cell RNA - HBF TERT88 [nTPM]":"72.5","Cell RNA - HDLM-2 [nTPM]":"26.5","Cell RNA - HEK 293 [nTPM]":"30.0","Cell RNA - HEL [nTPM]":"41.4","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"60.9","Cell RNA - HHSteC [nTPM]":"172.9","Cell RNA - HL-60 [nTPM]":"99.9","Cell RNA - HMC-1 [nTPM]":"113.1","Cell RNA - HSkMC [nTPM]":"216.7","Cell RNA - hTCEpi [nTPM]":"101.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.4","Cell RNA - hTERT-HME1 [nTPM]":"89.3","Cell RNA - hTERT-RPE1 [nTPM]":"210.3","Cell RNA - HUVEC TERT2 [nTPM]":"107.4","Cell RNA - JURKAT [nTPM]":"48.4","Cell RNA - K-562 [nTPM]":"65.1","Cell RNA - Karpas-707 [nTPM]":"197.6","Cell RNA - LHCN-M2 [nTPM]":"156.0","Cell RNA - MCF7 [nTPM]":"33.9","Cell RNA - MOLT-4 [nTPM]":"21.7","Cell RNA - NB-4 [nTPM]":"50.0","Cell RNA - NTERA-2 [nTPM]":"16.0","Cell RNA - OE19 [nTPM]":"128.9","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"22.3","Cell RNA - RH-30 [nTPM]":"60.6","Cell RNA - RPMI-8226 [nTPM]":"75.3","Cell RNA - RPTEC TERT1 [nTPM]":"129.1","Cell RNA - RT4 [nTPM]":"61.6","Cell RNA - SCLC-21H [nTPM]":"23.8","Cell RNA - SH-SY5Y [nTPM]":"26.4","Cell RNA - SiHa [nTPM]":"136.5","Cell RNA - SK-BR-3 [nTPM]":"126.6","Cell RNA - SK-MEL-30 [nTPM]":"307.3","Cell RNA - SuSa [nTPM]":"56.1","Cell RNA - T-47d [nTPM]":"23.4","Cell RNA - THP-1 [nTPM]":"123.9","Cell RNA - TIME [nTPM]":"54.1","Cell RNA - U-138 MG [nTPM]":"171.9","Cell RNA - U-2 OS [nTPM]":"70.7","Cell RNA - U-2197 [nTPM]":"160.1","Cell RNA - U-251 MG [nTPM]":"59.3","Cell RNA - U-266\/70 [nTPM]":"104.7","Cell RNA - U-266\/84 [nTPM]":"151.8","Cell RNA - U-698 [nTPM]":"33.4","Cell RNA - U-87 MG [nTPM]":"62.1","Cell RNA - U-937 [nTPM]":"130.4","Cell RNA - WM-115 [nTPM]":"85.3","Blood RNA - basophil [nTPM]":"24.2","Blood RNA - classical monocyte [nTPM]":"84.6","Blood RNA - eosinophil [nTPM]":"60.1","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"35.7","Blood RNA - MAIT T-cell [nTPM]":"38.7","Blood RNA - memory B-cell [nTPM]":"41.1","Blood RNA - memory CD4 T-cell [nTPM]":"28.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.9","Blood RNA - myeloid DC [nTPM]":"98.0","Blood RNA - naive B-cell [nTPM]":"38.0","Blood RNA - naive CD4 T-cell [nTPM]":"22.5","Blood RNA - naive CD8 T-cell [nTPM]":"33.2","Blood RNA - neutrophil [nTPM]":"8.1","Blood RNA - NK-cell [nTPM]":"51.3","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"37.3","Blood RNA - T-reg [nTPM]":"28.2","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"18.3","Brain RNA - basal ganglia [nTPM]":"21.1","Brain RNA - cerebellum [nTPM]":"20.4","Brain RNA - cerebral cortex [nTPM]":"21.6","Brain RNA - hippocampal formation [nTPM]":"19.9","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"21.3","Brain RNA - pons [nTPM]":"24.6","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"27.0","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"68.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"46.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"94.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"42.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"68.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"66.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"150.2","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"88.3","Single Cell Type RNA - Early spermatids [nTPM]":"20.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"50.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"68.0","Single Cell Type RNA - Fibroblasts [nTPM]":"78.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.6","Single Cell Type RNA - granulocytes [nTPM]":"29.9","Single Cell Type RNA - Granulosa cells [nTPM]":"49.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.5","Single Cell Type RNA - Hepatocytes [nTPM]":"42.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"234.3","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.3","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"92.8","Single Cell Type RNA - Langerhans cells [nTPM]":"75.0","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"74.3","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"94.3","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"60.3","Single Cell Type RNA - Muller glia cells [nTPM]":"38.4","Single Cell Type RNA - NK-cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.1","Single Cell Type RNA - Paneth cells [nTPM]":"74.6","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"37.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"68.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.3","Single Cell Type RNA - Spermatogonia [nTPM]":"32.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"157.6","Single Cell Type RNA - T-cells [nTPM]":"36.7","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"HEXB","Gene synonym":[],"Ensembl":"ENSG00000049860","Gene description":"Hexosaminidase subunit beta","Uniprot":["P07686"],"Chromosome":"5","Position":"74640023-74722647","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Gangliosidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"466.5","Hofbauer cells":"340.2","Syncytiotrophoblasts":"493.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"746.0","GAMG":"646.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055409","HPA056010"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"40000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055409":"AB_2682808","HPA056010":"AB_2683008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"92.2","Tissue RNA - adrenal gland [nTPM]":"72.0","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"59.7","Tissue RNA - basal ganglia [nTPM]":"25.3","Tissue RNA - bone marrow [nTPM]":"59.9","Tissue RNA - breast [nTPM]":"83.0","Tissue RNA - cerebellum [nTPM]":"22.3","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"97.6","Tissue RNA - choroid plexus [nTPM]":"39.4","Tissue RNA - colon [nTPM]":"105.0","Tissue RNA - duodenum [nTPM]":"99.0","Tissue RNA - endometrium 1 [nTPM]":"71.5","Tissue RNA - epididymis [nTPM]":"321.4","Tissue RNA - esophagus [nTPM]":"38.5","Tissue RNA - fallopian tube [nTPM]":"66.7","Tissue RNA - gallbladder [nTPM]":"99.0","Tissue RNA - heart muscle [nTPM]":"84.3","Tissue RNA - hippocampal formation [nTPM]":"23.1","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"81.6","Tissue RNA - liver [nTPM]":"137.5","Tissue RNA - lung [nTPM]":"111.3","Tissue RNA - lymph node [nTPM]":"47.0","Tissue RNA - medulla oblongata [nTPM]":"23.8","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"62.4","Tissue RNA - pancreas [nTPM]":"103.6","Tissue RNA - parathyroid gland [nTPM]":"94.2","Tissue RNA - pituitary gland [nTPM]":"46.6","Tissue RNA - placenta [nTPM]":"319.4","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"98.7","Tissue RNA - rectum [nTPM]":"116.9","Tissue RNA - retina [nTPM]":"33.6","Tissue RNA - salivary gland [nTPM]":"123.4","Tissue RNA - seminal vesicle [nTPM]":"54.0","Tissue RNA - skeletal muscle [nTPM]":"43.3","Tissue RNA - skin 1 [nTPM]":"54.3","Tissue RNA - small intestine [nTPM]":"75.4","Tissue RNA - smooth muscle [nTPM]":"76.1","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"64.7","Tissue RNA - stomach 1 [nTPM]":"88.4","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"28.2","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"89.6","Tissue RNA - tongue [nTPM]":"38.4","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"94.6","Tissue RNA - vagina [nTPM]":"64.1","Tissue RNA - white matter [nTPM]":"30.4","Cell RNA - A-431 [nTPM]":"147.3","Cell RNA - A549 [nTPM]":"111.0","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"131.8","Cell RNA - ASC diff [nTPM]":"746.0","Cell RNA - ASC TERT1 [nTPM]":"232.3","Cell RNA - BEWO [nTPM]":"122.3","Cell RNA - BJ [nTPM]":"173.5","Cell RNA - BJ hTERT+ [nTPM]":"590.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"175.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.2","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"194.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"133.0","Cell RNA - fHDF\/TERT166 [nTPM]":"152.2","Cell RNA - GAMG [nTPM]":"646.3","Cell RNA - HaCaT [nTPM]":"115.2","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"185.2","Cell RNA - HBF TERT88 [nTPM]":"228.7","Cell RNA - HDLM-2 [nTPM]":"79.2","Cell RNA - HEK 293 [nTPM]":"72.6","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"101.4","Cell RNA - Hep G2 [nTPM]":"101.5","Cell RNA - HHSteC [nTPM]":"216.5","Cell RNA - HL-60 [nTPM]":"16.2","Cell RNA - HMC-1 [nTPM]":"152.3","Cell RNA - HSkMC [nTPM]":"206.7","Cell RNA - hTCEpi [nTPM]":"108.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"180.7","Cell RNA - hTERT-HME1 [nTPM]":"121.3","Cell RNA - hTERT-RPE1 [nTPM]":"275.9","Cell RNA - HUVEC TERT2 [nTPM]":"204.5","Cell RNA - JURKAT [nTPM]":"47.3","Cell RNA - K-562 [nTPM]":"54.3","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"194.9","Cell RNA - MCF7 [nTPM]":"145.7","Cell RNA - MOLT-4 [nTPM]":"19.8","Cell RNA - NB-4 [nTPM]":"36.6","Cell RNA - NTERA-2 [nTPM]":"36.8","Cell RNA - OE19 [nTPM]":"142.7","Cell RNA - PC-3 [nTPM]":"47.8","Cell RNA - REH [nTPM]":"43.9","Cell RNA - RH-30 [nTPM]":"56.2","Cell RNA - RPMI-8226 [nTPM]":"191.8","Cell RNA - RPTEC TERT1 [nTPM]":"119.8","Cell RNA - RT4 [nTPM]":"130.4","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"134.2","Cell RNA - SK-BR-3 [nTPM]":"92.6","Cell RNA - SK-MEL-30 [nTPM]":"180.0","Cell RNA - SuSa [nTPM]":"68.8","Cell RNA - T-47d [nTPM]":"99.1","Cell RNA - THP-1 [nTPM]":"108.6","Cell RNA - TIME [nTPM]":"118.5","Cell RNA - U-138 MG [nTPM]":"112.1","Cell RNA - U-2 OS [nTPM]":"26.6","Cell RNA - U-2197 [nTPM]":"207.8","Cell RNA - U-251 MG [nTPM]":"165.6","Cell RNA - U-266\/70 [nTPM]":"102.6","Cell RNA - U-266\/84 [nTPM]":"191.3","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"257.9","Cell RNA - U-937 [nTPM]":"143.6","Cell RNA - WM-115 [nTPM]":"209.8","Blood RNA - basophil [nTPM]":"86.2","Blood RNA - classical monocyte [nTPM]":"343.2","Blood RNA - eosinophil [nTPM]":"99.1","Blood RNA - gdT-cell [nTPM]":"69.3","Blood RNA - intermediate monocyte [nTPM]":"129.9","Blood RNA - MAIT T-cell [nTPM]":"80.7","Blood RNA - memory B-cell [nTPM]":"45.2","Blood RNA - memory CD4 T-cell [nTPM]":"56.1","Blood RNA - memory CD8 T-cell [nTPM]":"64.0","Blood RNA - myeloid DC [nTPM]":"310.8","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"52.6","Blood RNA - naive CD8 T-cell [nTPM]":"51.3","Blood RNA - neutrophil [nTPM]":"125.2","Blood RNA - NK-cell [nTPM]":"42.4","Blood RNA - non-classical monocyte [nTPM]":"82.5","Blood RNA - plasmacytoid DC [nTPM]":"93.4","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"269.0","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"25.3","Brain RNA - cerebellum [nTPM]":"22.3","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"23.1","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"23.8","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"28.2","Brain RNA - white matter [nTPM]":"30.4","Single Cell Type RNA - Adipocytes [nTPM]":"49.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"31.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"82.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"103.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"10.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"63.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"466.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"68.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"151.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"23.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"125.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"175.4","Single Cell Type RNA - Fibroblasts [nTPM]":"107.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.9","Single Cell Type RNA - granulocytes [nTPM]":"69.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.3","Single Cell Type RNA - Hepatocytes [nTPM]":"70.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"340.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.7","Single Cell Type RNA - Ionocytes [nTPM]":"107.8","Single Cell Type RNA - Kupffer cells [nTPM]":"127.3","Single Cell Type RNA - Langerhans cells [nTPM]":"134.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"85.1","Single Cell Type RNA - Macrophages [nTPM]":"168.8","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"114.2","Single Cell Type RNA - Muller glia cells [nTPM]":"35.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.8","Single Cell Type RNA - Paneth cells [nTPM]":"54.8","Single Cell Type RNA - Peritubular cells [nTPM]":"72.2","Single Cell Type RNA - Plasma cells [nTPM]":"71.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"99.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"79.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"493.6","Single Cell Type RNA - T-cells [nTPM]":"35.3","Single Cell Type RNA - Theca cells [nTPM]":"31.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"81.8","Single Cell Type RNA - Urothelial cells [nTPM]":"71.0"},{"Gene":"HEXD","Gene synonym":["FLJ23825","HEXDC"],"Ensembl":"ENSG00000169660","Gene description":"Hexosaminidase D","Uniprot":["Q8WVB3"],"Chromosome":"17","Position":"82418318-82442645","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"7.8","Cardiomyocytes":"6.1","Cytotrophoblasts":"5.9","dendritic cells":"10.1","Extravillous trophoblasts":"6.4","Hofbauer cells":"16.2","Plasma cells":"4.1","Syncytiotrophoblasts":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"62.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022834","HPA023379","HPA027844"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoli fibrillar center","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA022834":"AB_1850641","HPA023379":"AB_1850643","HPA027844":"AB_10600711"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-5"},"Tissue RNA - adipose tissue [nTPM]":"31.5","Tissue RNA - adrenal gland [nTPM]":"20.5","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"32.5","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"17.0","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"22.4","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"27.0","Tissue RNA - liver [nTPM]":"29.8","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.0","Tissue RNA - ovary [nTPM]":"29.9","Tissue RNA - pancreas [nTPM]":"55.2","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"31.9","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"34.6","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"28.4","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"36.1","Tissue RNA - stomach 1 [nTPM]":"21.3","Tissue RNA - testis [nTPM]":"12.5","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"5.0","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"17.6","Tissue RNA - vagina [nTPM]":"21.1","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"5.9","Cell RNA - ASC diff [nTPM]":"11.3","Cell RNA - ASC TERT1 [nTPM]":"9.9","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"11.1","Cell RNA - Daudi [nTPM]":"9.5","Cell RNA - EFO-21 [nTPM]":"4.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"8.4","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"9.9","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"7.3","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.3","Cell RNA - hTERT-HME1 [nTPM]":"4.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"5.9","Cell RNA - K-562 [nTPM]":"5.5","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"10.0","Cell RNA - NB-4 [nTPM]":"8.6","Cell RNA - NTERA-2 [nTPM]":"3.7","Cell RNA - OE19 [nTPM]":"6.5","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"11.5","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"17.9","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"5.5","Cell RNA - SK-MEL-30 [nTPM]":"9.1","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"10.7","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"2.2","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"14.6","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"7.0","Cell RNA - U-87 MG [nTPM]":"2.3","Cell RNA - U-937 [nTPM]":"6.9","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"5.6","Blood RNA - gdT-cell [nTPM]":"18.4","Blood RNA - intermediate monocyte [nTPM]":"24.3","Blood RNA - MAIT T-cell [nTPM]":"12.4","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.9","Blood RNA - memory CD8 T-cell [nTPM]":"6.5","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"11.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"9.3","Blood RNA - neutrophil [nTPM]":"5.5","Blood RNA - NK-cell [nTPM]":"25.4","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"62.3","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"11.2","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.0","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - dendritic cells [nTPM]":"10.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HGSNAT","Gene synonym":["FLJ32731","HGNAT","TMEM76"],"Ensembl":"ENSG00000165102","Gene description":"Heparan-alpha-glucosaminide N-acetyltransferase","Uniprot":["Q68CP4"],"Chromosome":"8","Position":"43140464-43202855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029578":"AB_10602423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"20.0","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"25.4","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"30.1","Tissue RNA - epididymis [nTPM]":"30.6","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"29.0","Tissue RNA - gallbladder [nTPM]":"25.9","Tissue RNA - heart muscle [nTPM]":"23.3","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"17.6","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"26.6","Tissue RNA - lung [nTPM]":"24.5","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"13.3","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"35.9","Tissue RNA - pancreas [nTPM]":"29.9","Tissue RNA - parathyroid gland [nTPM]":"22.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"26.9","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"23.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"35.4","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"25.1","Tissue RNA - spinal cord [nTPM]":"11.4","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"23.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"15.7","Tissue RNA - urinary bladder [nTPM]":"25.2","Tissue RNA - vagina [nTPM]":"28.7","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"36.0","Cell RNA - AF22 [nTPM]":"8.9","Cell RNA - AN3-CA [nTPM]":"18.0","Cell RNA - ASC diff [nTPM]":"71.7","Cell RNA - ASC TERT1 [nTPM]":"53.8","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"30.5","Cell RNA - BJ hTERT+ [nTPM]":"36.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.3","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"39.2","Cell RNA - Daudi [nTPM]":"14.8","Cell RNA - EFO-21 [nTPM]":"20.5","Cell RNA - fHDF\/TERT166 [nTPM]":"42.9","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"15.5","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"12.7","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"16.3","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"25.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.7","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"34.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"10.0","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"7.2","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"16.3","Cell RNA - PC-3 [nTPM]":"5.4","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"16.1","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.1","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"39.0","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"19.0","Cell RNA - T-47d [nTPM]":"43.7","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"46.3","Cell RNA - U-138 MG [nTPM]":"33.2","Cell RNA - U-2 OS [nTPM]":"5.4","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"12.7","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"26.8","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"20.8","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"8.8","Blood RNA - eosinophil [nTPM]":"9.4","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"15.8","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"8.8","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"5.0","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"17.6","Brain RNA - medulla oblongata [nTPM]":"13.3","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.4","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"39.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"26.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"50.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"26.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"37.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.4","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"51.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"34.3","Single Cell Type RNA - Langerhans cells [nTPM]":"58.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"35.1","Single Cell Type RNA - Macrophages [nTPM]":"43.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"33.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.5","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"31.6","Single Cell Type RNA - Plasma cells [nTPM]":"19.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - T-cells [nTPM]":"25.0","Single Cell Type RNA - Theca cells [nTPM]":"37.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.7"},{"Gene":"HPSE","Gene synonym":["HPA","HPSE1","HSE1"],"Ensembl":"ENSG00000173083","Gene description":"Heparanase","Uniprot":["Q9Y251"],"Chromosome":"4","Position":"83292461-83335153","Protein class":["Enzymes","Metabolic proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"16.4","Kupffer cells":"41.5","Macrophages":"20.2","monocytes":"33.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"27.2","neutrophil":"18.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"18.5","monocytes":"27.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"39.8","OE19":"40.1","TIME":"25.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"3.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009813","HPA055344"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6500000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009813":"AB_2120854","HPA055344":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.7","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"9.7","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"3.2","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"20.8","Cell RNA - HaCaT [nTPM]":"12.3","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"2.5","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"4.2","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"8.4","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.4","Cell RNA - hTERT-HME1 [nTPM]":"15.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"18.1","Cell RNA - JURKAT [nTPM]":"2.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"39.8","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"40.1","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"10.2","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"17.7","Cell RNA - SK-BR-3 [nTPM]":"9.8","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"2.6","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"11.4","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"27.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"10.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"18.5","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"7.9","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.7","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"2.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"41.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"20.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"33.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"HPSE2","Gene synonym":["HPA2","HPR2","UFS"],"Ensembl":"ENSG00000172987","Gene description":"Heparanase 2 (inactive)","Uniprot":["Q8WWQ2"],"Chromosome":"10","Position":"98457077-99235862","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.6","cervix":"36.7","vagina":"27.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"900.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"BJ hTERT+":"10.2","HEL":"20.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044603":"AB_10794051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"20.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"36.7","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"21.1","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"23.2","Tissue RNA - midbrain [nTPM]":"29.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"21.5","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"1.7","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"28.5","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"18.3","Tissue RNA - vagina [nTPM]":"27.6","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"10.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"20.2","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"20.9","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"21.1","Brain RNA - medulla oblongata [nTPM]":"23.2","Brain RNA - midbrain [nTPM]":"29.6","Brain RNA - pons [nTPM]":"21.5","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"28.5","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"900.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"29.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"97.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"48.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"IDS","Gene synonym":["ID2S","SIDS"],"Ensembl":"ENSG00000010404","Gene description":"Iduronate 2-sulfatase","Uniprot":["P22304"],"Chromosome":"X","Position":"149476988-149521096","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"323.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"194.3","basal ganglia":"212.9","cerebral cortex":"323.4","hippocampal formation":"320.5","white matter":"109.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078003"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078003":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.7","Tissue RNA - adrenal gland [nTPM]":"43.3","Tissue RNA - amygdala [nTPM]":"194.3","Tissue RNA - appendix [nTPM]":"29.5","Tissue RNA - basal ganglia [nTPM]":"212.9","Tissue RNA - bone marrow [nTPM]":"47.6","Tissue RNA - breast [nTPM]":"27.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"323.4","Tissue RNA - cervix [nTPM]":"37.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"35.7","Tissue RNA - duodenum [nTPM]":"21.1","Tissue RNA - endometrium 1 [nTPM]":"35.1","Tissue RNA - epididymis [nTPM]":"43.5","Tissue RNA - esophagus [nTPM]":"26.1","Tissue RNA - fallopian tube [nTPM]":"35.7","Tissue RNA - gallbladder [nTPM]":"26.3","Tissue RNA - heart muscle [nTPM]":"42.2","Tissue RNA - hippocampal formation [nTPM]":"320.5","Tissue RNA - hypothalamus [nTPM]":"25.7","Tissue RNA - kidney [nTPM]":"22.7","Tissue RNA - liver [nTPM]":"15.8","Tissue RNA - lung [nTPM]":"40.5","Tissue RNA - lymph node [nTPM]":"31.0","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"45.4","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"57.0","Tissue RNA - pituitary gland [nTPM]":"67.8","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"29.4","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"48.6","Tissue RNA - salivary gland [nTPM]":"24.7","Tissue RNA - seminal vesicle [nTPM]":"41.0","Tissue RNA - skeletal muscle [nTPM]":"25.1","Tissue RNA - skin 1 [nTPM]":"37.1","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"30.5","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"34.1","Tissue RNA - stomach 1 [nTPM]":"23.0","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"32.3","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"27.2","Tissue RNA - tongue [nTPM]":"38.9","Tissue RNA - tonsil [nTPM]":"36.0","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"109.4","Cell RNA - A-431 [nTPM]":"46.4","Cell RNA - A549 [nTPM]":"50.7","Cell RNA - AF22 [nTPM]":"19.6","Cell RNA - AN3-CA [nTPM]":"12.7","Cell RNA - ASC diff [nTPM]":"22.1","Cell RNA - ASC TERT1 [nTPM]":"40.9","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"26.6","Cell RNA - BJ hTERT+ [nTPM]":"67.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.9","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"32.7","Cell RNA - Daudi [nTPM]":"110.0","Cell RNA - EFO-21 [nTPM]":"69.6","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"49.1","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"21.3","Cell RNA - HBEC3-KT [nTPM]":"40.5","Cell RNA - HBF TERT88 [nTPM]":"30.1","Cell RNA - HDLM-2 [nTPM]":"40.8","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"14.7","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"17.8","Cell RNA - HL-60 [nTPM]":"18.8","Cell RNA - HMC-1 [nTPM]":"101.3","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.9","Cell RNA - hTERT-HME1 [nTPM]":"33.1","Cell RNA - hTERT-RPE1 [nTPM]":"95.5","Cell RNA - HUVEC TERT2 [nTPM]":"37.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"76.6","Cell RNA - LHCN-M2 [nTPM]":"34.7","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"19.6","Cell RNA - NB-4 [nTPM]":"9.3","Cell RNA - NTERA-2 [nTPM]":"17.5","Cell RNA - OE19 [nTPM]":"28.8","Cell RNA - PC-3 [nTPM]":"34.3","Cell RNA - REH [nTPM]":"12.4","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"20.7","Cell RNA - RPTEC TERT1 [nTPM]":"27.8","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"28.9","Cell RNA - SH-SY5Y [nTPM]":"67.6","Cell RNA - SiHa [nTPM]":"9.8","Cell RNA - SK-BR-3 [nTPM]":"22.1","Cell RNA - SK-MEL-30 [nTPM]":"32.0","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"7.9","Cell RNA - TIME [nTPM]":"44.3","Cell RNA - U-138 MG [nTPM]":"29.9","Cell RNA - U-2 OS [nTPM]":"31.3","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"70.8","Cell RNA - U-266\/70 [nTPM]":"54.5","Cell RNA - U-266\/84 [nTPM]":"47.3","Cell RNA - U-698 [nTPM]":"79.3","Cell RNA - U-87 MG [nTPM]":"138.0","Cell RNA - U-937 [nTPM]":"44.3","Cell RNA - WM-115 [nTPM]":"22.1","Blood RNA - basophil [nTPM]":"117.5","Blood RNA - classical monocyte [nTPM]":"56.9","Blood RNA - eosinophil [nTPM]":"171.7","Blood RNA - gdT-cell [nTPM]":"70.9","Blood RNA - intermediate monocyte [nTPM]":"63.0","Blood RNA - MAIT T-cell [nTPM]":"53.2","Blood RNA - memory B-cell [nTPM]":"35.2","Blood RNA - memory CD4 T-cell [nTPM]":"43.1","Blood RNA - memory CD8 T-cell [nTPM]":"54.0","Blood RNA - myeloid DC [nTPM]":"48.7","Blood RNA - naive B-cell [nTPM]":"27.0","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"42.9","Blood RNA - neutrophil [nTPM]":"261.1","Blood RNA - NK-cell [nTPM]":"37.2","Blood RNA - non-classical monocyte [nTPM]":"73.9","Blood RNA - plasmacytoid DC [nTPM]":"36.8","Blood RNA - T-reg [nTPM]":"74.0","Blood RNA - total PBMC [nTPM]":"63.0","Brain RNA - amygdala [nTPM]":"194.3","Brain RNA - basal ganglia [nTPM]":"212.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"323.4","Brain RNA - hippocampal formation [nTPM]":"320.5","Brain RNA - hypothalamus [nTPM]":"25.7","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"32.3","Brain RNA - white matter [nTPM]":"109.4","Single Cell Type RNA - Adipocytes [nTPM]":"53.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"64.4","Single Cell Type RNA - Astrocytes [nTPM]":"55.8","Single Cell Type RNA - B-cells [nTPM]":"150.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"60.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"178.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"58.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"158.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"50.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.8","Single Cell Type RNA - Endothelial cells [nTPM]":"44.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"168.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"232.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.7","Single Cell Type RNA - Fibroblasts [nTPM]":"78.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.5","Single Cell Type RNA - granulocytes [nTPM]":"226.2","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"33.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.0","Single Cell Type RNA - Horizontal cells [nTPM]":"222.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"243.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"73.2","Single Cell Type RNA - Kupffer cells [nTPM]":"94.8","Single Cell Type RNA - Langerhans cells [nTPM]":"109.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"72.7","Single Cell Type RNA - Macrophages [nTPM]":"98.4","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"120.9","Single Cell Type RNA - Muller glia cells [nTPM]":"55.0","Single Cell Type RNA - NK-cells [nTPM]":"146.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"85.0","Single Cell Type RNA - Paneth cells [nTPM]":"50.3","Single Cell Type RNA - Peritubular cells [nTPM]":"89.5","Single Cell Type RNA - Plasma cells [nTPM]":"98.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"74.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"68.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.0","Single Cell Type RNA - T-cells [nTPM]":"183.9","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"96.9"},{"Gene":"IDUA","Gene synonym":["MPS1","MPSI"],"Ensembl":"ENSG00000127415","Gene description":"Alpha-L-iduronidase","Uniprot":["P35475"],"Chromosome":"4","Position":"986997-1004564","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"19.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"29.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025901","HPA046979","HPA054254"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025901":null,"HPA046979":"AB_2679888","HPA054254":"AB_2682429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"13.5","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"10.3","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"15.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"13.9","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"17.0","Tissue RNA - pancreas [nTPM]":"21.0","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"17.2","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"17.1","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.1","Cell RNA - ASC diff [nTPM]":"12.7","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"10.7","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"10.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"1.0","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"5.8","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"3.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"11.9","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"2.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.5","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"5.7","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"9.3","Cell RNA - U-138 MG [nTPM]":"9.0","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"29.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"7.8","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"1.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"4.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"13.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.6","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"5.6","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"KL","Gene synonym":[],"Ensembl":"ENSG00000133116","Gene description":"Klotho","Uniprot":["Q9UEF7"],"Chromosome":"13","Position":"33016423-33066143","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosidase","Hormone","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"47.1","kidney":"128.7","parathyroid gland":"135.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal tubular cells":"123.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"5.9","renal cancer":"17.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"2.4","SK-BR-3":"4.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"13.3","cerebral cortex":"6.7","hippocampal formation":"7.4","medulla oblongata":"4.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":510000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"47.1","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"2.7","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"128.7","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"3.5","Tissue RNA - lymph node [nTPM]":"1.0","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"135.2","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"30.4","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.5","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"123.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"NAGLU","Gene synonym":["NAG"],"Ensembl":"ENSG00000108784","Gene description":"N-acetyl-alpha-glucosaminidase","Uniprot":["P54802"],"Chromosome":"17","Position":"42536241-42544449","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Mucopolysaccharidosis","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038815"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038815":"AB_10697398"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.6","Tissue RNA - adrenal gland [nTPM]":"37.9","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"14.8","Tissue RNA - basal ganglia [nTPM]":"21.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"35.3","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"16.7","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"28.7","Tissue RNA - colon [nTPM]":"25.1","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"34.7","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"19.5","Tissue RNA - fallopian tube [nTPM]":"27.6","Tissue RNA - gallbladder [nTPM]":"27.4","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"15.0","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"59.3","Tissue RNA - lung [nTPM]":"30.8","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"18.0","Tissue RNA - midbrain [nTPM]":"19.2","Tissue RNA - ovary [nTPM]":"35.2","Tissue RNA - pancreas [nTPM]":"63.8","Tissue RNA - parathyroid gland [nTPM]":"21.3","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"26.1","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"28.3","Tissue RNA - rectum [nTPM]":"16.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"37.7","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"16.0","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"40.7","Tissue RNA - stomach 1 [nTPM]":"35.1","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"19.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"37.6","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"28.9","Tissue RNA - vagina [nTPM]":"23.9","Tissue RNA - white matter [nTPM]":"30.0","Cell RNA - A-431 [nTPM]":"16.0","Cell RNA - A549 [nTPM]":"55.3","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"106.6","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"36.4","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"56.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.7","Cell RNA - CACO-2 [nTPM]":"14.9","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"20.3","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"54.7","Cell RNA - HaCaT [nTPM]":"38.3","Cell RNA - HAP1 [nTPM]":"9.7","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"20.2","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"31.3","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"27.7","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"17.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.6","Cell RNA - hTERT-HME1 [nTPM]":"16.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.8","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"39.3","Cell RNA - LHCN-M2 [nTPM]":"27.9","Cell RNA - MCF7 [nTPM]":"38.9","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"23.0","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"34.6","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"47.2","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"36.1","Cell RNA - SCLC-21H [nTPM]":"16.2","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"12.9","Cell RNA - SK-BR-3 [nTPM]":"17.6","Cell RNA - SK-MEL-30 [nTPM]":"20.4","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"82.1","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"59.3","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"23.8","Cell RNA - U-251 MG [nTPM]":"15.7","Cell RNA - U-266\/70 [nTPM]":"52.6","Cell RNA - U-266\/84 [nTPM]":"25.8","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"35.9","Cell RNA - U-937 [nTPM]":"14.4","Cell RNA - WM-115 [nTPM]":"43.1","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"21.6","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"16.7","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"15.0","Brain RNA - medulla oblongata [nTPM]":"18.0","Brain RNA - midbrain [nTPM]":"19.2","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"19.5","Brain RNA - white matter [nTPM]":"30.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.3","Single Cell Type RNA - B-cells [nTPM]":"9.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"4.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.5","Single Cell Type RNA - Fibroblasts [nTPM]":"26.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"43.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"19.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"6.0","Single Cell Type RNA - Theca cells [nTPM]":"74.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"SGSH","Gene synonym":["HSS","MPS3A","SFMD"],"Ensembl":"ENSG00000181523","Gene description":"N-sulfoglucosamine sulfohydrolase","Uniprot":["P51688"],"Chromosome":"17","Position":"80206716-80220923","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"32.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"62.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023436","HPA023451"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023436":"AB_1856806","HPA023451":"AB_1856807"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"45.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"12.2","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"13.5","Tissue RNA - choroid plexus [nTPM]":"8.8","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"12.7","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"13.4","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"16.0","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"21.8","Tissue RNA - seminal vesicle [nTPM]":"11.1","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"17.8","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"11.5","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"2.6","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"22.5","Cell RNA - ASC TERT1 [nTPM]":"20.2","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"16.0","Cell RNA - BJ hTERT+ [nTPM]":"40.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.2","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.7","Cell RNA - fHDF\/TERT166 [nTPM]":"24.9","Cell RNA - GAMG [nTPM]":"13.2","Cell RNA - HaCaT [nTPM]":"9.9","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"5.3","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"22.3","Cell RNA - Hep G2 [nTPM]":"25.0","Cell RNA - HHSteC [nTPM]":"62.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"5.9","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"10.5","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"50.7","Cell RNA - JURKAT [nTPM]":"4.7","Cell RNA - K-562 [nTPM]":"7.1","Cell RNA - Karpas-707 [nTPM]":"26.2","Cell RNA - LHCN-M2 [nTPM]":"17.9","Cell RNA - MCF7 [nTPM]":"16.2","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"13.2","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.2","Cell RNA - RT4 [nTPM]":"18.5","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"11.7","Cell RNA - SiHa [nTPM]":"18.4","Cell RNA - SK-BR-3 [nTPM]":"44.1","Cell RNA - SK-MEL-30 [nTPM]":"10.6","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"32.8","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"31.9","Cell RNA - U-2 OS [nTPM]":"7.0","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"26.1","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"3.9","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"20.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"12.1","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"16.0","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.5","Blood RNA - memory CD8 T-cell [nTPM]":"11.3","Blood RNA - myeloid DC [nTPM]":"20.4","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"9.3","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"12.7","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.8","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"32.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"}]