Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;kidney: 3.7;liver: 3.1;skeletal muscle: 4.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Excitatory neurons: 2.7;Hepatocytes: 3.4;Inhibitory neurons: 2.8;Proximal tubular cells: 5.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "T-47d: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA058258: AB_2683656" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-2)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" 1.7 0.6 0.8 0.1 1.3 0.0 0.1 5.0 2.5 0.0 2.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.8 1.2 0.0 3.7 3.1 0.1 0.1 0.6 0.3 0.5 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.2 0.0 4.0 0.0 0.1 0.0 0.4 0.2 0.0 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 1.8 0.1 0.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 5.0 2.5 1.2 0.0 0.6 0.3 1.0 0.4 0.5 0.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7" "Cell type enhanced" "Detected in many" "granulocytes: 137.2;Late spermatids: 160.8;Proximal enterocytes: 179.4;Proximal tubular cells: 253.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.2;plasmacytoid DC: 35.7" "Group enriched" "Detected in many" 5 "dendritic cells: 35.7;NK-cells: 40.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 11.3 20.4 72.8 18.7 72.8 14.7 9.9 56.2 108.2 17.8 16.7 32.7 55.1 18.2 5.5 35.0 11.0 8.2 17.3 75.1 107.2 47.8 22.0 17.9 22.4 96.1 88.5 11.2 9.0 3.8 65.1 10.4 128.7 12.9 21.4 24.5 11.9 6.9 5.2 27.1 56.1 23.5 46.9 20.7 19.2 38.1 83.9 28.3 6.1 4.7 19.4 18.0 23.5 68.4 117.6 100.0 96.6 104.6 21.7 35.6 36.4 98.6 50.6 142.7 85.1 347.7 37.0 142.4 70.6 80.4 110.3 113.0 156.9 263.2 53.2 126.0 136.7 75.2 74.4 124.9 88.7 88.8 59.9 32.1 49.6 118.2 139.2 38.1 81.2 174.8 62.3 29.8 76.8 136.6 187.0 94.0 48.5 116.9 228.2 219.9 110.6 95.6 80.9 44.2 52.6 149.1 88.9 134.5 317.9 47.3 47.9 41.2 133.0 129.1 75.4 129.6 158.9 24.9 110.6 202.1 81.8 153.7 80.3 0.0 0.3 0.2 7.3 1.2 1.8 2.1 5.8 6.2 5.4 0.7 2.0 3.9 0.7 40.2 0.9 35.7 8.2 5.3 72.8 72.8 56.2 108.2 75.1 107.2 96.1 88.5 128.7 46.9 83.9 68.4 3.4 6.4 16.4 9.4 4.9 31.7 16.5 24.2 12.5 46.8 4.1 7.5 9.8 8.6 14.9 9.2 10.4 20.9 14.4 45.4 15.6 22.7 95.5 4.0 6.1 19.1 4.8 26.5 38.6 7.2 29.7 11.5 19.9 7.6 137.2 13.2 8.6 16.8 30.1 47.1 38.9 110.2 36.7 4.8 85.9 160.8 3.7 13.4 39.2 5.6 15.7 12.8 8.2 22.6 21.0 23.2 41.8 7.2 9.3 9.5 179.4 253.7 7.1 24.4 0.0 6.7 17.6 37.8 28.0 26.2 29.5 17.2 21.7 13.7 51.3 19.6 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 191.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 199.8;Hepatocytes: 287.4;Proximal enterocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 77.2;neutrophil: 113.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 113.7" "Cell line enhanced" "Detected in all" "BEWO: 96.9;RT4: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" 37.8 18.1 16.1 10.6 18.2 8.8 17.1 17.4 15.1 11.0 21.3 40.9 62.5 9.3 9.8 30.4 9.9 14.9 23.0 14.3 17.5 40.3 191.5 13.6 6.2 16.6 17.9 9.5 39.7 18.8 12.6 17.3 15.9 18.4 27.1 16.1 15.4 11.8 30.1 24.8 51.4 11.1 17.5 10.5 27.4 9.3 20.6 8.3 17.0 29.2 12.1 19.5 12.7 18.9 16.3 24.5 7.2 9.9 34.0 14.4 96.9 11.8 11.3 12.9 14.8 16.4 24.0 9.1 14.0 17.9 12.5 9.9 28.7 12.4 19.2 10.0 9.5 10.9 13.1 47.2 19.4 9.7 7.8 24.0 9.4 15.7 9.2 13.1 32.3 13.6 12.3 8.9 14.0 45.3 26.3 7.0 4.9 36.8 19.8 13.4 21.3 10.2 20.7 129.1 8.7 12.6 30.6 46.5 11.4 21.2 32.6 11.3 20.9 18.2 13.4 15.2 11.5 14.4 11.0 4.0 10.0 9.7 11.4 77.2 18.3 5.2 6.9 14.2 8.2 5.4 6.6 8.8 10.3 4.5 7.2 7.1 113.7 7.2 9.4 9.4 9.3 8.0 16.1 18.2 17.4 15.1 14.3 17.5 16.6 17.9 15.9 17.5 20.6 18.9 28.0 28.9 25.0 25.1 10.8 13.5 15.9 26.1 21.1 27.4 19.4 13.5 47.4 51.5 23.4 23.9 22.9 37.7 12.1 199.8 21.5 22.9 11.6 18.1 16.7 18.8 34.4 21.5 17.8 40.6 46.5 19.8 88.7 24.1 17.1 21.4 21.8 287.4 25.4 18.5 18.8 44.5 24.4 35.4 14.1 7.1 29.8 23.7 14.2 15.0 36.3 61.9 9.2 22.1 18.2 34.2 100.0 47.0 18.3 24.0 238.7 107.8 17.4 28.4 0.0 18.4 17.2 5.5 11.0 28.5 30.3 43.2 13.2 17.1 41.9 31.7 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035840, HPA035841" Uncertain Supported Peroxisomes NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Peroxisomes "HPA035840: AB_10696514, HPA035841: AB_10671940" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.12e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.52e-2)" "unprognostic (1.81e-3)" "unprognostic (2.21e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" "unprognostic (4.43e-2)" "unprognostic (4.81e-1)" "unprognostic (1.39e-1)" "unprognostic (1.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.65e-1)" 7.7 8.8 5.8 6.4 5.2 4.4 12.2 3.8 7.2 9.5 5.9 8.4 8.9 5.6 4.3 26.6 6.6 5.9 16.2 5.3 4.9 6.5 14.9 7.2 6.6 5.9 4.6 7.5 12.0 7.1 4.5 8.4 4.7 10.5 6.3 3.8 15.4 8.4 6.4 12.5 8.9 11.4 4.2 5.3 10.1 2.9 5.0 4.6 8.5 5.6 8.5 10.1 13.7 7.1 8.9 9.6 10.5 14.1 11.0 18.7 17.2 11.1 15.1 18.5 16.1 4.8 11.7 11.9 11.7 22.8 25.0 5.4 4.6 14.4 14.3 4.1 4.5 5.2 8.2 14.8 18.3 10.7 9.4 18.9 12.1 16.7 6.5 13.3 22.1 13.1 7.0 10.6 16.1 8.2 11.4 15.6 5.9 11.3 16.4 11.8 17.3 14.3 11.2 12.4 5.1 11.7 14.2 7.2 7.3 8.6 7.2 14.9 21.7 18.2 5.9 7.5 11.8 7.9 5.6 5.4 23.2 13.1 11.8 0.1 13.2 3.3 6.1 15.2 6.3 5.4 7.1 7.8 17.8 4.9 6.5 6.7 3.1 9.5 14.4 21.4 10.4 9.4 5.8 5.2 3.8 7.2 5.3 4.9 5.9 4.6 4.7 4.2 5.0 7.1 6.2 6.4 5.9 14.7 4.8 4.5 7.6 12.3 8.6 8.2 11.6 7.6 9.4 10.0 9.8 11.0 33.3 23.9 7.7 10.9 3.9 17.3 4.4 13.1 4.2 5.6 1.8 3.0 13.2 13.7 9.3 6.6 10.2 10.0 0.0 21.7 4.6 14.2 10.2 1.7 14.2 4.9 14.2 4.1 4.4 3.3 6.8 5.3 5.4 6.5 7.6 3.8 2.1 12.5 14.5 16.9 7.4 11.3 5.6 9.1 18.3 8.2 11.2 18.6 0.0 3.8 6.9 2.4 2.3 14.1 5.8 74.6 6.0 6.0 7.5 11.4 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 56.6;skin 1: 14.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 158.0" "Cancer enriched" "Detected in some" 4 "glioma: 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SK-MEL-30: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 0.1 5.5 23.0 0.4 42.6 2.4 1.6 30.5 24.0 0.5 0.0 1.1 0.4 0.2 0.7 0.3 2.8 0.2 0.8 19.6 35.9 0.5 0.4 0.5 0.4 46.0 39.9 0.3 0.2 0.0 0.5 0.1 47.7 0.8 0.1 0.6 0.3 0.2 0.2 14.3 0.5 0.2 45.8 0.3 0.3 3.7 36.6 3.4 0.2 0.0 0.1 0.3 0.5 56.6 0.3 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.6 0.3 0.0 0.2 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.4 0.2 0.4 0.0 0.1 0.2 0.5 3.1 0.2 0.1 0.1 0.4 0.2 0.0 0.4 0.2 0.3 0.1 0.4 1.5 0.3 0.1 0.2 0.4 0.2 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.3 23.0 42.6 30.5 24.0 19.6 35.9 46.0 39.9 47.7 45.8 36.6 56.6 0.1 0.0 2.0 158.0 0.6 1.1 0.6 0.3 0.6 1.9 0.2 0.1 3.0 0.0 2.7 0.0 4.2 0.2 0.5 0.3 0.0 0.0 1.8 4.4 0.3 0.2 0.0 4.6 0.7 0.0 0.2 0.7 0.5 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.7 0.3 4.0 1.8 2.8 0.1 0.2 1.0 7.5 26.9 0.2 0.0 0.0 0.9 0.3 0.1 0.2 19.1 3.3 0.0 0.3 1.0 2.0 10.0 0.4 0.6 0.4 0.5 1.6 0.1 0.7 ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 89 "testis: 129.3" "Group enriched" "Detected in some" 75 "Early spermatids: 533.6;Late spermatids: 1782.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA043421: AB_10794182, HPA051013: AB_2681311" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" 0.1 0.0 0.2 0.0 0.2 0.0 0.2 1.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 129.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.2 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 533.6 0.0 0.1 0.6 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1782.3 11.8 0.8 0.0 1.9 0.0 0.0 0.0 1.5 3.1 0.0 0.0 7.2 0.0 0.0 0.0 1.9 0.0 0.0 6.6 0.0 0.1 15.4 9.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.3;Glandular and luminal cells: 208.8;granulocytes: 633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 16000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" 44.2 40.6 11.9 38.8 14.1 16.2 19.8 13.2 14.8 48.2 5.6 12.7 15.4 19.2 17.7 15.8 13.4 29.2 29.4 16.5 23.7 46.4 13.9 39.0 24.6 17.6 20.8 14.9 11.9 19.8 9.2 21.4 21.3 13.4 13.6 24.7 10.6 15.2 42.6 9.9 13.4 22.0 13.7 22.2 19.3 26.8 14.6 20.3 18.6 16.9 18.5 68.0 10.6 18.9 67.3 21.3 24.2 28.3 97.8 61.6 20.3 94.0 107.6 91.0 97.4 21.1 45.0 46.2 35.4 71.7 100.9 19.4 22.4 92.0 143.0 15.7 23.3 181.4 26.6 223.3 44.8 44.8 360.0 51.4 36.7 103.6 74.0 50.2 71.8 25.5 5.6 54.2 100.7 4.7 40.7 60.7 31.6 15.2 37.2 26.4 45.4 39.6 136.3 20.9 15.2 12.3 109.3 0.4 63.2 49.0 1.9 45.8 128.5 81.1 22.6 129.3 85.9 28.1 31.7 41.2 139.7 97.8 52.2 32.5 10.9 35.0 4.2 15.5 3.2 3.3 3.9 3.5 10.6 3.1 3.0 3.8 29.6 4.0 19.4 4.0 6.7 6.5 11.9 14.1 13.2 14.8 16.5 23.7 17.6 20.8 21.3 13.7 14.6 18.9 27.9 76.9 184.3 29.0 19.5 22.3 25.7 20.0 81.4 44.2 7.3 8.1 37.2 15.7 40.1 73.5 2.1 7.3 18.3 0.8 50.9 27.7 1.4 79.5 27.0 29.8 7.7 26.1 76.7 25.4 36.9 46.0 7.1 208.8 633.8 151.6 18.2 44.2 23.9 6.7 78.3 5.7 2.0 64.9 59.1 4.9 5.6 67.8 16.0 57.1 70.4 10.9 8.2 71.4 116.4 32.3 3.0 10.1 36.1 19.4 0.7 12.4 12.2 16.7 0.0 20.0 27.9 3.7 5.3 10.1 8.1 31.6 25.2 34.9 2.7 18.4 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 5151.4" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 975.2" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "Hep G2: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 20000000 "Cluster 34: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favorable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" 2.1 0.8 0.5 0.4 0.4 0.4 4.3 1.2 1.0 1.5 0.0 0.6 164.1 0.2 0.5 0.8 0.3 0.4 0.2 0.4 0.7 1.5 5151.4 0.2 0.2 0.1 0.1 0.1 0.4 0.1 0.0 0.2 0.1 0.3 0.6 0.8 2.6 0.5 0.6 0.9 22.9 0.1 0.0 0.6 0.6 1.0 0.5 0.0 0.4 2.1 0.1 0.3 3.4 0.2 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.4 22.2 0.0 1.6 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.8 0.0 0.1 0.1 0.5 0.3 0.0 0.1 0.1 1.6 0.5 0.0 0.1 0.1 0.2 1.5 0.3 0.0 0.1 0.4 0.0 0.1 0.4 0.1 0.3 0.0 0.4 0.4 0.6 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 1.2 1.0 0.4 0.7 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 21.5 0.2 1.8 0.0 0.0 0.0 0.8 0.0 0.0 26.9 0.7 0.6 1.1 0.0 45.5 0.1 0.6 0.0 1.0 0.0 0.3 0.0 0.0 16.1 975.2 0.0 0.0 0.0 1.1 0.0 27.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.8 0.0 ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" 141.5 71.3 48.3 52.5 48.2 28.5 111.9 48.0 56.0 92.7 55.8 158.8 94.2 134.8 142.2 114.4 95.9 69.3 124.3 45.9 54.6 175.4 264.1 73.5 51.3 47.6 48.5 118.4 49.4 50.1 41.4 60.9 47.9 116.2 100.8 36.0 65.4 124.6 80.9 54.8 94.3 118.0 49.7 51.6 91.3 52.2 48.6 83.3 79.2 75.8 55.5 158.9 73.9 51.4 84.0 66.9 194.8 110.0 344.7 316.0 116.6 136.6 237.6 143.8 125.2 77.1 96.7 96.5 77.5 197.8 92.8 69.8 135.0 188.7 137.7 69.9 56.6 67.1 83.3 306.7 332.2 118.4 51.9 287.3 143.1 108.3 84.7 151.0 112.8 99.8 125.8 53.3 192.3 94.9 160.4 105.4 156.7 20.6 79.8 115.4 108.9 50.9 230.2 96.0 74.0 97.0 82.7 96.6 155.9 141.8 78.2 82.2 85.4 130.5 82.9 86.4 95.2 55.9 74.4 135.4 134.2 77.4 135.7 21.8 21.2 35.8 32.6 18.9 29.5 26.0 35.3 30.4 23.8 26.2 34.0 31.9 3.0 51.3 14.1 20.5 49.5 32.8 48.3 48.2 48.0 56.0 45.9 54.6 47.6 48.5 47.9 49.7 48.6 51.4 69.0 105.8 78.2 22.9 48.1 39.6 85.9 257.5 109.3 31.8 32.1 74.3 127.4 78.6 94.3 55.2 10.4 290.1 51.8 80.4 197.6 94.8 24.0 146.9 159.1 56.3 79.7 45.8 14.3 83.8 277.2 131.2 37.8 113.0 26.6 83.3 47.2 188.0 118.1 38.7 12.0 101.8 87.5 48.6 27.1 22.0 187.4 43.4 53.4 15.9 63.2 152.4 77.2 27.6 13.9 78.4 86.0 255.1 41.5 34.9 95.2 316.0 56.8 46.5 111.7 55.6 127.7 30.5 48.5 74.9 23.0 83.0 58.5 147.0 104.8 68.1 ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Group enriched" "Detected in some" 6 "Hepatocytes: 325.5;Proximal tubular cells: 92.4" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Hep G2: 44.7" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" 0.2 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 8.2 41.5 0.3 0.0 0.3 9.2 7.7 0.0 0.0 0.0 52.3 703.8 0.2 0.2 0.1 0.2 0.0 0.3 0.0 0.0 0.2 0.1 0.1 8.6 0.0 0.0 0.1 0.0 1.8 22.6 0.3 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 44.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 9.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.5 0.1 0.5 0.0 0.0 0.0 0.0 0.3 15.7 1.1 5.5 0.0 0.0 0.0 7.8 7.9 0.3 0.0 11.2 0.3 0.4 12.1 0.0 0.1 0.2 0.0 0.1 0.0 0.4 0.0 0.0 7.1 325.5 0.0 0.0 0.1 8.9 8.2 5.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 31.1 92.4 15.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 12.7 0.1 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 185.7 14.3 12.3 13.5 16.5 5.8 116.2 16.0 11.5 12.9 6.9 23.2 25.3 6.6 6.6 103.9 11.5 65.7 135.5 10.9 18.7 45.4 623.2 28.9 4.7 22.1 18.4 15.5 23.3 0.8 9.7 1.7 23.2 17.3 12.2 11.5 73.7 12.5 120.4 35.3 23.4 8.7 19.6 4.1 142.9 13.0 22.2 4.6 46.7 27.3 7.8 71.1 31.3 20.3 0.0 429.6 2.4 426.7 2988.3 358.2 0.2 13.7 95.9 5.4 4.1 8.4 0.5 0.0 6.1 97.7 72.5 3.6 1.6 22.4 2.5 0.1 0.2 12.6 65.6 5415.7 30.0 1.8 0.0 183.9 27.3 44.2 26.7 0.4 10.2 2.9 95.8 0.4 74.7 2.4 0.1 0.4 1.2 2297.1 1.5 0.1 0.8 4.2 24.3 81.4 0.4 1.7 23.8 0.7 0.8 1.3 0.5 7.8 85.3 36.0 2.3 97.6 4.5 1.6 0.5 0.3 129.3 12.1 0.9 1.5 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 0.1 0.2 12.3 16.5 16.0 11.5 10.9 18.7 22.1 18.4 23.2 19.6 22.2 20.3 21.6 67.3 34.4 2.0 2.4 21.2 27.8 253.8 262.4 3.1 7.6 1.0 3.2 284.5 144.5 62.5 0.0 0.1 0.2 5.9 13.7 67.0 24.0 3.3 1.7 17.1 1.8 52.6 3.4 328.0 0.1 176.3 139.1 4.6 4.5 0.8 21.0 597.7 0.4 0.0 3.1 6.8 20.3 16.1 15.6 9.9 151.6 3.3 106.7 13.1 4.6 51.5 0.0 4.5 0.5 120.2 3.6 147.4 0.4 41.3 20.2 61.9 72.2 4.5 0.0 16.4 24.3 1.9 1.1 229.3 20.5 0.1 2.1 6.4 20.3 306.0 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 613.3" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 6.6;OE19: 2.9" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 0.4 41.8 0.0 0.0 0.0 0.3 717.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.2 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 37.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.2 0.0 0.8 0.0 13.5 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 13.6 613.3 0.0 0.0 0.0 0.6 0.0 14.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.2 1.0 1.5 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996049-7010754 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.6;esophagus: 49.4;vagina: 105.7" "Cell type enriched" "Detected in some" 6 "Macrophages: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "A-431: 25.5;HEL: 40.4" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.4" "HPA010691, CAB019287, HPA064819" Enhanced Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 49000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Vesicles" "CAB019287: , HPA010691: AB_1844756, HPA064819: " "unprognostic (3.61e-3)" "unprognostic (6.93e-2)" "unprognostic (7.17e-5)" "unprognostic (9.43e-2)" "unprognostic (6.06e-2)" "unprognostic (2.25e-3)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-5)" "unprognostic (4.01e-3)" "unprognostic (2.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" 1.0 1.5 0.9 3.2 1.5 4.7 0.3 0.1 1.4 34.6 0.6 0.4 1.8 2.2 0.0 49.4 1.2 3.1 1.4 0.4 0.4 0.5 0.2 1.1 3.9 1.3 0.7 1.3 1.9 0.0 0.1 1.1 1.0 0.8 0.1 3.1 20.2 0.0 1.6 21.7 2.0 0.2 0.1 3.3 1.1 1.3 1.2 0.0 1.9 0.1 3.8 1.5 105.7 3.4 25.5 4.2 1.9 1.4 0.0 0.0 1.7 1.6 0.0 0.0 0.0 3.7 0.9 1.3 0.9 0.0 1.4 3.2 0.0 0.1 0.0 2.8 3.2 40.4 6.8 2.8 0.1 0.4 6.5 0.0 0.1 0.0 0.0 2.4 0.0 2.8 2.7 1.4 0.0 0.3 0.5 0.9 1.3 0.2 0.8 1.4 0.8 0.7 0.0 3.2 0.1 0.9 0.7 0.8 0.4 2.4 1.5 1.1 4.6 2.2 1.2 2.1 1.1 0.8 0.3 0.7 1.2 3.0 1.0 2.1 0.9 1.8 0.7 0.4 0.5 1.1 0.5 0.7 0.7 0.6 0.2 0.3 4.5 0.7 0.4 1.3 0.3 13.6 0.9 1.5 0.1 1.4 0.4 0.4 1.3 0.7 1.0 0.1 1.2 3.4 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 17.3 0.0 1.0 0.8 0.0 0.0 2.5 2.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.5 1.1 0.0 0.1 0.1 0.0 2.0 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 996.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.4;CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.1 0.0 0.5 0.0 0.5 1.2 0.0 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 17.4 0.1 0.5 0.4 0.3 721.0 0.4 0.0 0.4 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.4 0.8 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.5 1.0 0.5 0.4 0.4 0.3 0.5 0.1 0.3 0.8 0.3 0.0 0.0 0.7 2.4 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.1 0.7 0.0 16.0 9.7 0.2 0.0 0.1 0.0 0.1 0.0 0.0 12.1 996.7 0.0 0.0 7.2 0.0 0.0 18.2 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 3.0 0.9 1.8 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.4 0.0 BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Proximal tubular cells: 795.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 46.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" 45.0 96.6 23.3 4.3 25.8 3.5 39.7 27.0 27.3 46.6 27.1 31.8 39.4 31.2 16.6 27.2 43.4 14.9 46.6 20.3 27.8 162.1 70.5 35.9 6.7 28.4 26.5 54.8 23.2 30.8 29.2 7.7 27.0 31.9 10.3 8.5 32.8 14.1 24.6 26.1 39.6 9.6 25.2 21.2 38.9 14.8 28.2 17.5 62.9 16.7 7.3 37.1 37.3 26.5 3.1 5.3 26.5 10.0 30.4 29.4 3.4 6.7 17.8 6.9 10.6 3.4 11.8 12.4 11.1 10.2 2.1 1.5 17.3 10.1 8.2 8.2 8.5 1.5 6.4 8.1 15.0 7.4 2.1 24.8 9.1 10.6 2.6 23.0 20.7 14.3 8.0 5.5 24.1 1.0 37.2 6.3 9.6 2.0 2.1 24.5 30.7 7.9 46.4 3.6 4.5 12.0 12.8 6.7 7.9 9.6 5.7 5.3 9.9 10.7 3.4 5.5 3.7 8.1 7.9 12.5 11.8 8.9 5.4 2.6 2.5 0.2 7.6 1.4 8.8 4.8 6.6 6.0 3.2 6.7 9.8 10.4 0.4 6.5 0.2 5.0 10.2 4.0 23.3 25.8 27.0 27.3 20.3 27.8 28.4 26.5 27.0 25.2 28.2 26.5 37.7 32.1 57.8 33.6 10.2 30.3 47.1 59.4 36.5 2.5 31.9 36.1 9.6 64.3 46.9 108.5 0.0 7.9 19.0 18.0 211.3 58.2 1.9 60.6 45.5 30.3 22.9 16.4 1.2 21.3 18.5 75.2 41.8 27.9 19.6 39.1 27.8 71.6 20.4 3.3 3.8 24.4 46.8 10.9 16.9 4.8 69.9 12.5 23.2 14.0 14.9 50.4 14.4 3.5 21.8 23.0 18.6 77.8 8.0 18.9 162.3 795.7 48.7 3.8 13.1 40.9 36.5 0.9 4.0 25.9 26.7 3.4 18.2 52.6 37.6 37.5 CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 583.9" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 524.2;Distal tubular cells: 757.2;Proximal enterocytes: 1270.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 12000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 45: Intestine - Brush border" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "CAB034291: AB_2070856, HPA018433: AB_1846109" "prognostic favorable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favorable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" 32.4 95.3 150.0 25.6 200.0 10.1 29.5 186.1 174.1 52.7 207.0 68.6 583.9 41.3 50.5 189.5 34.6 47.1 29.5 154.6 166.7 125.6 252.8 41.1 28.3 173.1 175.1 28.8 36.1 38.6 35.3 27.6 175.6 48.7 50.9 10.2 101.8 42.2 33.6 111.8 345.9 34.4 166.2 39.9 133.5 18.1 180.3 22.7 46.4 23.3 36.7 51.0 85.3 266.6 114.4 180.4 22.6 55.9 115.0 115.3 1.2 123.6 97.0 72.4 86.4 68.9 67.8 28.2 78.7 128.1 137.3 84.6 46.3 132.3 55.7 133.8 95.3 82.5 105.1 48.1 65.7 49.1 77.5 56.1 165.6 70.7 30.8 83.0 78.4 0.0 0.0 21.3 67.6 121.2 24.7 50.7 0.4 0.0 123.3 0.4 0.4 80.5 195.7 60.9 60.5 52.1 121.3 186.3 157.3 17.6 86.1 69.4 71.1 78.8 30.8 202.9 96.1 131.8 268.9 0.7 144.0 48.6 115.6 7.1 134.0 68.6 64.4 198.5 54.6 67.2 79.7 60.8 109.6 61.2 102.6 75.4 9.2 77.3 156.9 39.6 89.0 162.1 150.0 200.0 186.1 174.1 154.6 166.7 173.1 175.1 175.6 166.2 180.3 266.6 26.4 121.8 69.3 17.9 22.5 128.2 63.1 295.2 524.2 11.6 27.7 98.8 20.9 77.2 117.1 95.6 2.1 116.6 15.7 91.2 757.2 93.7 8.9 31.7 45.5 23.1 38.6 32.0 6.5 70.0 80.4 65.7 127.4 45.1 34.9 30.8 41.7 277.2 85.1 3.3 6.8 94.4 396.7 66.6 27.5 4.3 122.7 49.5 90.7 4.7 79.2 69.8 23.7 16.6 128.2 91.8 146.6 132.4 41.3 66.4 1270.3 326.0 121.2 8.3 26.3 51.3 90.7 5.8 17.4 403.5 123.6 89.2 30.7 55.6 145.8 55.0 CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.3;salivary gland: 41.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 102.5;Basal squamous epithelial cells: 107.0;Peritubular cells: 75.6;Squamous epithelial cells: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 23.9;NK-cells: 11.5;T-cells: 33.7" "Cell line enhanced" "Detected in many" "RPMI-8226: 64.9" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA018434: AB_1846110" "unprognostic (3.64e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-2)" "unprognostic (3.75e-1)" "unprognostic (9.10e-2)" "prognostic unfavorable (5.95e-6)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.99e-3)" "unprognostic (1.94e-1)" 17.3 2.3 12.8 4.0 14.7 1.4 15.3 13.9 19.8 12.4 11.2 7.8 3.0 7.5 11.0 56.3 8.8 6.5 6.1 13.2 12.4 2.7 0.8 4.6 2.9 12.8 12.1 11.2 1.6 0.6 2.4 2.9 12.3 9.9 3.6 0.6 41.4 5.1 3.1 21.6 5.4 6.1 12.0 3.1 5.2 3.1 12.2 2.0 4.6 7.8 7.6 11.6 16.8 12.4 33.5 9.5 4.0 8.2 31.0 47.8 5.9 35.4 42.4 40.6 32.1 0.4 6.9 0.0 10.2 37.2 13.7 15.0 5.5 7.2 16.2 45.3 17.2 1.4 10.0 0.3 2.6 0.1 0.1 6.8 0.8 28.1 3.6 19.1 24.9 3.7 0.0 0.3 12.1 25.4 3.1 14.7 3.2 10.3 41.5 6.7 7.6 64.9 13.7 14.2 2.1 2.9 27.3 32.6 53.3 2.2 9.8 3.9 17.1 25.7 2.2 28.8 35.0 1.5 0.6 0.0 26.9 0.9 47.3 0.0 0.6 0.1 2.2 0.5 3.0 23.6 25.1 7.7 2.4 23.9 33.7 23.5 0.9 11.5 1.0 0.7 10.9 11.5 12.8 14.7 13.9 19.8 13.2 12.4 12.8 12.1 12.3 12.0 12.2 12.4 41.7 0.0 3.2 6.8 5.2 71.0 22.1 102.5 107.0 0.8 23.1 38.6 0.2 2.8 23.0 0.0 0.0 1.2 2.9 1.9 9.8 4.7 0.7 13.1 7.5 26.5 0.0 1.7 3.9 0.7 0.3 53.4 7.7 14.7 5.7 1.1 14.3 0.3 8.4 0.0 5.5 12.6 69.2 3.8 41.3 4.0 67.7 5.8 65.8 2.8 20.9 1.9 0.0 1.5 0.5 2.6 1.7 75.6 1.4 43.4 1.3 0.2 13.1 0.6 0.0 21.4 19.7 0.4 0.2 230.4 46.7 0.3 7.0 1.0 8.1 21.1 CBR4 "FLJ14431, SDR45C1" ENSG00000145439 "Carbonyl reductase 4" Q8N4T8 4 168863770-169010275 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037499 Supported NA NA 51000 "Cluster 18: Basophils - Vesicular transport" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA037499: AB_10672386" "unprognostic (1.60e-1)" "unprognostic (8.25e-2)" "unprognostic (1.37e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (2.39e-2)" "unprognostic (2.41e-3)" "unprognostic (4.06e-2)" "unprognostic (1.29e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-1)" "unprognostic (6.64e-2)" "prognostic favorable (3.64e-14)" "unprognostic (1.97e-2)" "unprognostic (2.00e-1)" "unprognostic (1.81e-2)" "unprognostic (7.38e-3)" 9.1 14.1 11.2 7.9 13.1 6.7 14.1 13.1 14.4 9.4 12.4 12.1 12.8 9.9 20.1 8.3 9.3 8.1 17.8 11.1 12.4 27.3 49.6 7.3 11.0 12.8 12.3 11.0 10.0 11.7 9.9 8.1 13.4 11.7 13.9 17.5 13.2 11.2 17.3 15.7 11.8 8.8 11.7 9.4 10.8 7.5 12.7 9.7 15.6 15.9 11.5 8.4 8.4 15.9 9.0 6.6 20.2 12.8 17.2 20.3 4.1 6.3 8.6 7.5 6.9 7.9 9.3 18.3 3.4 4.9 7.0 9.4 18.8 20.1 8.2 7.0 9.3 32.3 16.9 10.7 10.3 12.9 10.9 13.4 17.1 5.4 9.1 17.8 22.4 15.3 17.8 14.4 12.0 4.6 13.5 21.0 7.3 6.2 10.0 11.6 7.1 8.0 26.5 9.4 17.9 13.4 7.7 10.9 16.7 16.7 11.7 8.2 13.4 7.8 4.2 8.8 6.4 14.2 10.2 8.8 13.6 15.6 4.9 7.9 4.0 6.4 6.6 3.6 3.9 5.7 4.5 6.4 3.5 7.5 4.9 6.4 3.0 5.8 5.3 4.8 4.0 2.1 11.2 13.1 13.1 14.4 11.1 12.4 12.8 12.3 13.4 11.7 12.7 15.9 16.1 0.0 9.4 86.2 24.2 23.1 32.2 27.7 10.8 37.3 20.7 12.1 30.0 28.6 19.9 49.7 39.6 40.6 19.8 24.2 50.9 66.5 16.1 22.5 17.5 20.5 29.3 34.9 68.0 42.9 27.5 17.8 16.8 15.8 2.5 36.0 24.7 81.6 24.9 62.2 82.3 26.5 34.6 26.6 8.9 34.6 44.4 16.8 35.6 61.8 26.1 28.3 46.4 150.3 135.8 37.6 39.8 31.2 8.7 24.6 31.7 93.4 19.8 51.3 59.2 18.5 16.3 56.6 41.6 15.3 20.2 20.2 15.9 38.3 27.4 29.6 CTBP1 BARS ENSG00000159692 "C-terminal binding protein 1" Q13363 4 1211445-1249953 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004217, HPA018987, HPA044971" Approved Enhanced Nucleoplasm NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB004217: AB_627312, HPA018987: AB_1847307, HPA044971: AB_2679161" "unprognostic (6.19e-2)" "unprognostic (4.78e-2)" "unprognostic (9.14e-2)" "prognostic favorable (4.03e-4)" "unprognostic (3.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.52e-2)" "unprognostic (1.04e-2)" "unprognostic (9.65e-2)" "unprognostic (2.24e-2)" "unprognostic (6.35e-3)" "unprognostic (3.58e-2)" "unprognostic (3.36e-1)" "unprognostic (2.46e-2)" "unprognostic (3.00e-1)" "unprognostic (3.22e-2)" "prognostic favorable (8.94e-4)" 76.1 88.1 92.3 86.1 91.2 71.5 72.7 96.6 104.3 94.7 73.6 94.6 91.0 98.4 47.5 85.0 89.2 61.4 100.0 92.7 98.1 88.4 109.2 82.6 108.7 99.2 94.1 93.5 141.1 58.8 140.0 45.7 94.6 94.8 41.9 38.8 90.9 50.8 170.1 74.3 97.1 48.1 77.1 118.7 79.5 47.3 90.0 98.1 86.2 91.5 62.4 87.5 79.8 89.8 108.5 156.8 118.4 146.6 81.5 58.6 101.7 83.4 76.8 101.8 102.8 135.0 255.1 131.0 93.8 97.5 156.6 84.1 72.3 109.9 30.4 101.0 86.6 119.1 185.6 177.1 135.7 108.4 163.3 101.3 82.5 86.5 49.8 97.8 76.8 147.1 138.1 219.6 56.9 178.1 351.4 338.3 140.5 87.8 148.4 244.4 71.4 173.2 65.8 135.9 222.0 138.1 79.6 85.2 114.5 70.9 187.2 164.5 99.7 168.5 94.2 97.8 182.1 157.7 164.3 155.2 133.4 166.4 135.6 12.6 15.6 17.4 31.8 23.1 24.0 20.1 22.3 27.4 20.6 19.3 17.1 25.1 12.7 23.9 23.9 34.6 20.9 16.1 92.3 91.2 96.6 104.3 92.7 98.1 99.2 94.1 94.6 77.1 90.0 89.8 33.3 41.7 39.0 17.9 36.8 34.2 21.1 22.1 13.1 32.1 52.0 39.5 54.9 37.1 19.2 36.8 4.2 25.4 72.4 57.2 11.7 29.4 4.0 34.0 46.4 35.7 46.1 42.3 19.4 40.6 32.0 37.5 37.8 41.6 24.1 31.2 45.0 85.0 43.0 40.4 21.2 49.7 20.3 72.9 31.8 5.5 45.1 37.7 46.2 21.5 45.9 46.8 82.4 19.6 17.7 45.0 35.7 35.7 42.0 36.9 42.8 37.4 25.7 17.8 6.6 31.2 32.9 10.8 13.4 30.3 37.8 19.8 41.1 32.0 57.5 27.9 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.1;urinary bladder: 63.6" "Cell type enhanced" "Detected in some" "Adipocytes: 21.9;Endothelial cells: 13.7;Glandular and luminal cells: 5.9;Hepatocytes: 9.9;Urothelial cells: 16.4" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 36.9;hTCEpi: 19.5;HUVEC TERT2: 19.1;SK-BR-3: 14.7;SuSa: 35.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" 18.5 0.6 0.2 0.0 0.2 0.0 14.7 0.1 0.3 3.6 0.0 2.0 0.6 2.4 0.6 1.9 1.2 0.7 10.7 0.2 0.4 1.4 66.1 12.2 0.0 0.3 0.4 0.5 0.6 0.0 0.5 0.3 0.3 0.7 0.1 0.3 1.8 0.6 4.1 13.9 19.8 0.0 0.1 0.1 1.8 0.3 0.2 0.2 2.0 0.2 0.1 63.6 2.2 0.1 0.3 2.1 0.2 0.0 0.5 0.1 11.7 0.0 0.1 0.7 0.3 36.9 1.6 0.3 9.6 0.0 8.8 11.4 0.7 7.3 0.3 0.0 1.0 0.5 2.6 5.5 0.2 0.3 11.5 0.0 19.5 0.3 1.4 0.4 19.1 0.3 2.3 0.3 0.1 0.7 0.1 0.4 0.2 12.1 2.9 1.2 0.0 0.4 0.0 2.4 0.6 0.3 1.7 14.7 3.8 35.6 0.4 0.2 1.0 1.6 0.5 5.2 0.0 0.7 0.2 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.4 0.3 0.4 0.3 0.1 0.2 0.1 21.9 0.0 0.0 0.0 0.1 0.5 2.4 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 3.4 1.1 13.7 0.0 0.0 0.1 0.2 0.0 0.2 0.0 5.9 0.0 0.0 0.0 9.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 16.4 CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 313 "liver: 513.4" "Cell type enriched" "Detected in some" 57 "Hepatocytes: 85.7" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-BR-3: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" 0.2 0.3 0.5 0.2 0.5 1.0 0.1 1.6 0.8 0.0 0.2 0.0 0.2 0.2 0.4 0.1 0.2 0.2 0.1 0.5 0.5 0.2 513.4 0.4 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.3 0.3 0.6 0.2 0.0 0.1 0.3 0.2 0.3 0.6 0.1 1.4 0.0 0.1 0.1 0.0 1.3 0.4 0.3 0.8 0.5 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.4 0.8 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.4 0.9 0.6 0.1 0.0 0.7 0.3 0.1 0.1 0.0 0.0 0.3 0.1 1.3 0.7 1.3 0.0 0.2 0.9 0.3 0.4 0.3 0.2 0.9 0.8 0.3 0.1 0.7 0.7 0.3 0.6 2.3 0.1 0.6 0.5 0.2 0.2 0.3 0.4 0.3 0.3 0.3 0.2 0.5 0.3 0.9 0.3 1.5 0.3 0.5 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.2 2.1 0.4 0.2 0.4 0.1 0.1 0.5 0.5 1.6 0.8 0.5 0.5 0.6 0.5 0.6 0.1 0.6 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 85.7 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "liver: 2.0" "Group enriched" "Detected in some" 8 "Club cells: 2.0;Early spermatids: 4.2;Late spermatids: 3.7" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CYP2A6 "CPA6, CYP2A, CYP2A3" ENSG00000255974 "Cytochrome P450 family 2 subfamily A member 6" P11509 19 40843541-40850447 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 171 "liver: 1612.0" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 322.3" "Cancer enriched" "Detected in some" 12 "liver cancer: 281.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (4.10e-1)" "unprognostic (5.05e-2)" "unprognostic (2.64e-2)" "prognostic favorable (5.38e-5)" "unprognostic (4.98e-3)" "unprognostic (4.86e-2)" "unprognostic (6.23e-2)" "unprognostic (5.20e-2)" "unprognostic (1.95e-1)" "unprognostic (2.25e-2)" "unprognostic (8.83e-3)" "unprognostic (2.46e-1)" "unprognostic (3.07e-2)" "unprognostic (2.55e-1)" 0.6 0.2 0.0 0.0 0.1 0.0 9.4 0.0 0.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 1612.0 0.3 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.3 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.2 0.0 0.0 0.4 0.3 0.2 5.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 11.4 322.3 0.0 0.0 0.1 0.0 0.0 14.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 1.5 CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 71 "liver: 152.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 195.3" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.6 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 152.5 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 24.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 11.0 195.3 0.0 0.0 0.1 0.8 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.9 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 320.0" "Group enriched" "Detected in many" 35 "Hepatocytes: 512.8;Proximal enterocytes: 465.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.8" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.2 0.0 0.3 0.3 0.1 0.8 0.2 0.1 0.3 0.3 3.7 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.3 320.0 0.1 0.1 0.2 0.0 0.2 0.8 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 11.7 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.8 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.0 1.1 5.5 0.7 0.5 0.7 1.3 2.8 7.3 1.1 1.4 0.4 2.8 0.7 1.8 2.1 0.1 0.6 2.9 1.9 0.7 3.1 0.8 0.6 0.6 1.2 0.0 6.5 0.6 0.1 0.3 4.1 1.4 0.0 0.7 5.7 512.8 0.1 11.8 9.4 7.6 0.0 5.6 0.0 13.6 0.0 0.4 0.0 0.0 0.1 0.7 0.0 5.0 4.9 0.7 11.3 1.5 0.4 0.6 465.2 0.5 1.3 2.3 0.0 0.4 2.1 0.8 0.4 0.6 1.1 0.4 1.0 0.1 3.4 0.3 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP2F1 CYP2F ENSG00000197446 "Cytochrome P450 family 2 subfamily F member 1" P24903 19 41114432-41128381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.4;salivary gland: 1.0;testis: 2.1" "Cell type enriched" "Detected in some" 4 "Club cells: 67.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "HMC-1: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.04e-1)" "unprognostic (8.79e-2)" "unprognostic (4.63e-1)" "unprognostic (4.60e-2)" "unprognostic (2.54e-1)" "unprognostic (7.29e-3)" "unprognostic (6.23e-3)" "unprognostic (2.87e-2)" "unprognostic (3.91e-2)" "unprognostic (1.58e-6)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (1.50e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.5 0.0 67.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 16.5 0.0 0.0 0.0 1.6 8.0 5.3 1.5 0.0 0.0 0.6 0.0 0.0 0.1 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 44.7 0.1 0.1 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.8 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.2 0.0 0.0 3.9 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 6.4 0.1 1.7 1.9 0.0 0.0 0.6 1.9 3.3 0.0 0.2 0.0 1.0 0.0 0.2 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.7 0.1 2.4 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.2 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 304.9" "Group enriched" "Detected in some" 17 "Cholangiocytes: 85.8;Hepatocytes: 60.5" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.3;Hep G2: 2.5;HHSteC: 1.4" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" 0.2 0.9 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.2 0.5 0.3 0.3 0.1 0.0 6.5 0.0 0.0 0.1 8.5 304.9 2.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.1 85.8 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.3 60.5 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.8 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 1.3 0.0 0.2 CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.7" "Group enriched" "Detected in some" 10 "Cholangiocytes: 4.3;Hepatocytes: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 1.1 0.1 0.0 0.0 1.5 12.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.9;liver: 72.3" "Cell type enhanced" "Detected in many" "Ductal cells: 15.6;Hepatocytes: 62.9;Prostatic glandular cells: 36.3;Urothelial cells: 26.1" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.1;CAPAN-2: 50.4;EFO-21: 18.5;Hep G2: 25.0;RPMI-8226: 13.5;RT4: 15.2" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" 0.3 2.9 5.2 0.6 5.3 0.6 2.1 5.1 5.3 1.6 0.0 3.5 10.7 0.5 16.4 13.0 3.0 18.7 0.2 4.3 5.5 6.4 72.3 0.6 0.4 9.3 9.6 0.1 5.1 0.1 0.5 0.1 6.3 3.8 2.6 1.6 3.8 4.3 0.5 1.0 23.9 0.1 4.8 1.0 4.1 1.1 6.6 0.0 3.0 0.0 0.9 5.7 3.4 5.0 13.1 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 50.4 0.1 18.5 0.0 10.5 1.5 0.0 6.6 0.0 0.0 0.1 0.1 4.2 25.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 10.0 0.0 1.9 0.1 0.3 0.1 11.4 0.0 0.1 0.1 13.5 3.4 15.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.6 0.2 0.4 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.3 5.1 5.3 4.3 5.5 9.3 9.6 6.3 4.8 6.6 5.0 0.1 0.0 0.0 9.1 0.2 0.1 7.7 5.3 0.0 0.0 1.4 1.7 0.4 10.0 4.4 9.2 0.0 0.0 0.0 6.9 1.9 15.6 0.0 2.8 0.6 0.3 1.2 2.7 0.0 11.5 0.0 0.3 0.0 4.4 0.0 0.3 0.4 62.9 0.0 0.0 0.0 2.0 2.0 2.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 3.0 0.0 0.0 0.8 9.2 3.2 0.0 0.0 36.3 11.7 8.3 7.6 0.1 0.0 0.6 0.6 0.0 0.0 0.5 0.3 0.0 0.1 0.1 2.7 26.1 CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" 3.2 1.1 0.6 1.2 0.9 0.9 2.7 0.6 1.5 6.0 0.4 15.1 39.1 1.5 0.5 18.1 3.2 2.4 1.5 0.9 2.4 1.8 40.1 1.2 0.5 0.9 1.1 1.6 0.3 0.0 0.5 0.5 1.1 5.0 7.8 0.1 4.3 1.0 0.6 21.1 41.5 1.9 0.7 1.0 12.0 0.2 0.7 0.8 0.9 0.9 2.6 10.5 11.2 1.9 0.0 4.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.6 0.5 0.0 0.0 0.3 32.0 0.0 0.0 0.0 2.0 0.0 0.0 1.7 9.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.1 0.0 46.3 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.1 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.1 0.0 14.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.6 1.5 0.9 2.4 0.9 1.1 1.1 0.7 0.7 1.9 6.3 0.0 1.8 2.6 0.5 14.0 10.0 8.3 13.1 0.0 0.5 0.3 1.0 5.7 7.1 0.0 0.0 0.1 0.0 58.8 0.0 0.6 1.6 0.2 0.1 3.0 7.8 8.0 0.2 0.0 0.1 3.8 57.6 0.3 0.0 0.0 1.4 30.3 0.4 0.0 0.2 24.8 2.0 0.9 1.6 3.2 4.1 0.3 1.8 0.0 0.0 2.7 0.0 0.0 0.4 1.9 51.9 1.2 0.2 3.5 125.3 2.2 4.9 0.1 0.0 0.3 2.5 0.4 0.1 20.5 21.2 0.3 0.5 0.1 29.6 24.8 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 80.2;liver: 235.8" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 562.4" "Cancer enhanced" "Detected in many" "liver cancer: 30.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 63 "neutrophil: 84.1" "Lineage enriched" "Detected in single" 177 "granulocytes: 84.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 33.0;HaCaT: 14.9;Hep G2: 18.3;OE19: 49.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA058960 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA058960: AB_2683862" "unprognostic (1.73e-2)" "unprognostic (9.70e-3)" "unprognostic (1.21e-1)" "unprognostic (1.16e-3)" "unprognostic (5.40e-1)" "unprognostic (1.57e-1)" "unprognostic (7.15e-3)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-3)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" 1.6 0.1 0.9 1.2 3.3 80.2 0.2 2.3 1.3 6.9 0.3 2.1 9.4 0.1 0.8 26.7 1.1 15.5 0.3 1.8 2.2 27.3 235.8 2.3 0.1 2.8 3.0 0.0 0.6 0.0 0.5 0.4 2.9 0.6 1.8 0.0 3.4 0.6 0.1 3.9 15.0 0.3 1.9 7.8 5.1 0.3 1.9 0.7 0.1 0.6 0.7 2.9 9.0 4.1 0.3 7.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 33.0 0.1 0.2 0.0 0.1 14.9 0.0 0.2 0.0 0.6 0.0 0.1 3.5 18.3 0.0 0.2 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 49.3 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 84.1 0.0 0.1 0.0 0.0 0.1 0.9 3.3 2.3 1.3 1.8 2.2 2.8 3.0 2.9 1.9 1.9 4.1 0.0 9.6 3.7 0.7 2.0 1.0 2.1 2.5 1.2 0.0 0.1 0.1 0.9 62.9 5.0 0.0 0.0 0.0 1.4 10.0 0.0 2.3 0.1 0.9 0.2 0.7 53.1 17.3 0.0 0.2 0.2 0.8 7.7 3.1 1.3 0.0 8.2 562.4 0.0 0.0 0.0 14.4 8.2 11.4 0.3 0.7 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.0 7.4 0.0 0.0 3.2 69.9 32.1 1.9 0.0 0.0 0.7 1.3 0.0 0.3 25.7 6.5 0.0 1.1 0.0 10.9 13.1 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "seminal vesicle: 215.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.1" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.2 215.6 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.4 1.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 1.7 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 2.5 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.5;Club cells: 59.0;Excitatory neurons: 37.4;Respiratory ciliated cells: 104.6" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.6;CACO-2: 4.6;NTERA-2: 2.1;SCLC-21H: 2.7;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 11.6 3.2 8.2 0.7 8.5 0.1 14.9 5.2 10.2 37.1 2.8 1.6 1.7 2.1 2.7 14.7 9.3 1.6 8.6 8.7 12.1 5.9 10.5 8.8 1.9 4.5 5.6 1.2 1.7 1.7 3.8 1.1 5.7 8.0 1.9 2.3 31.1 2.9 4.6 7.1 1.4 1.9 4.1 0.6 22.3 4.0 9.2 1.1 5.0 4.0 9.1 3.3 7.2 6.4 0.0 0.0 0.0 0.0 2.6 0.2 0.1 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.3 0.0 0.4 0.2 2.7 0.0 0.0 0.2 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 8.5 5.2 10.2 8.7 12.1 4.5 5.6 5.7 4.1 9.2 6.4 4.4 22.4 17.0 2.3 0.0 2.5 26.9 37.5 25.0 2.4 31.0 0.9 0.8 1.5 59.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 8.4 7.6 0.8 4.0 0.0 0.0 37.4 0.7 0.0 7.1 4.1 1.4 0.0 0.0 1.1 2.8 3.9 0.0 29.3 0.2 18.3 0.6 0.7 8.6 10.5 0.5 5.4 4.7 0.0 0.1 0.0 1.0 2.0 0.1 0.0 20.7 0.0 8.4 0.5 1.7 104.6 0.8 0.0 2.0 19.1 0.5 3.6 21.4 1.4 0.1 0.5 0.1 1.9 31.8 CYP4Z1 CYP4A20 ENSG00000186160 "Cytochrome P450 family 4 subfamily Z member 1" Q86W10 1 47067231-47118318 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 6.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Breast glandular cells: 8.3;Early spermatids: 2.5;Excitatory neurons: 8.3;Inhibitory neurons: 5.8" "Cancer enriched" "Detected in some" 50 "breast cancer: 42.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HDLM-2: 8.1;SK-BR-3: 3.2" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.11e-2)" "unprognostic (2.57e-2)" "unprognostic (2.46e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (4.33e-4)" "unprognostic (1.10e-1)" "unprognostic (3.53e-3)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (3.53e-1)" "unprognostic (6.82e-3)" "unprognostic (5.09e-3)" "unprognostic (3.88e-2)" "unprognostic (6.46e-2)" "unprognostic (3.49e-3)" 2.2 0.2 0.9 0.0 0.9 0.0 6.3 0.2 1.1 0.3 0.0 0.2 0.0 0.3 0.3 0.7 0.6 0.0 0.8 0.8 1.3 0.2 0.7 1.6 0.0 0.4 0.4 0.0 0.1 0.0 0.6 0.0 0.3 1.2 0.0 0.0 0.8 0.3 0.7 1.0 0.2 0.0 0.2 0.0 0.4 0.4 1.1 0.2 0.5 0.2 0.2 0.4 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.2 1.1 0.8 1.3 0.4 0.4 0.3 0.2 1.1 0.9 0.3 9.6 1.1 1.0 0.0 0.1 0.5 0.4 0.0 0.0 8.3 0.4 0.4 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.5 0.2 0.1 0.9 0.0 0.0 8.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 165.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 129.2;Proximal enterocytes: 81.3;Proximal tubular cells: 159.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes Microtubules "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" 13.0 34.8 5.5 1.6 5.7 5.8 11.8 5.5 8.1 9.6 5.4 18.5 20.6 10.0 2.0 12.0 9.2 2.1 12.4 6.0 6.6 35.8 165.1 6.8 1.2 5.6 5.5 8.6 21.2 1.7 8.4 2.4 5.5 11.9 2.8 0.5 9.5 7.1 32.3 10.5 17.4 1.5 5.5 6.8 13.8 11.4 6.1 1.8 6.3 7.2 1.0 10.7 8.1 6.1 2.4 22.5 3.4 14.7 4.1 6.3 7.7 7.0 5.7 6.0 6.7 16.2 16.2 6.1 12.2 7.5 3.7 3.5 2.1 6.4 1.3 12.4 5.7 2.3 10.3 37.6 17.7 4.9 11.1 9.1 4.8 4.2 5.5 6.1 6.9 9.5 4.3 7.9 5.5 27.7 3.2 10.2 8.0 9.0 7.5 5.8 1.3 12.2 6.9 6.3 4.3 8.5 11.3 15.9 8.8 1.3 21.9 10.1 10.8 5.1 5.8 7.5 5.6 6.7 7.1 2.6 7.0 10.2 16.1 0.0 3.8 0.1 2.7 5.1 1.5 1.8 1.1 1.5 5.1 1.7 2.6 1.5 0.2 2.9 2.5 7.8 0.9 2.6 5.5 5.7 5.5 8.1 6.0 6.6 5.6 5.5 5.5 5.5 6.1 6.1 9.6 12.8 16.2 5.2 4.3 3.8 7.3 5.6 10.2 2.0 14.9 15.6 8.3 20.0 7.4 20.2 0.0 34.3 5.7 53.8 39.2 37.3 2.6 7.1 8.1 9.4 12.5 29.5 2.3 38.9 7.1 9.9 38.7 9.6 12.7 15.8 7.5 129.2 12.9 3.3 2.7 30.6 6.1 7.3 5.7 6.3 6.5 6.0 5.4 0.0 10.0 7.0 5.2 3.0 2.8 25.3 37.2 6.8 3.8 6.4 81.3 159.1 7.7 3.0 0.0 7.7 8.3 3.8 6.3 12.6 6.0 12.6 3.5 25.8 38.8 5.1 DGAT2L6 "DC3, FLJ25989" ENSG00000184210 "Diacylglycerol O-acyltransferase 2 like 6" Q6ZPD8 X 70177483-70205704 "Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "breast: 2.1;skin 1: 5.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "unprognostic (1.90e-2)" "unprognostic (3.08e-1)" "unprognostic (1.43e-3)" "unprognostic (3.47e-3)" "unprognostic (8.60e-2)" "unprognostic (5.82e-2)" "unprognostic (1.63e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953734-23969279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 235.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.21e-2)" "unprognostic (2.59e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (7.35e-3)" "unprognostic (1.61e-3)" "unprognostic (2.66e-1)" "unprognostic (1.19e-2)" "unprognostic (1.06e-2)" "unprognostic (7.65e-2)" "prognostic favorable (4.55e-6)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (5.68e-2)" 34.1 45.8 8.6 10.4 9.2 6.9 34.5 8.8 9.7 30.5 10.1 43.5 34.0 27.1 5.2 45.8 23.6 5.9 49.1 8.3 8.6 92.0 109.7 28.0 10.2 9.2 8.6 33.0 40.3 8.8 19.3 5.3 9.2 31.9 13.5 3.9 31.2 8.4 62.2 44.7 38.6 8.3 8.6 32.2 33.7 37.9 9.0 9.6 25.4 14.0 8.5 30.5 33.1 9.5 15.1 29.6 10.4 17.2 16.6 18.5 0.1 27.4 15.3 11.5 9.1 6.5 16.5 13.3 14.3 14.6 7.6 18.1 8.6 12.3 10.1 34.6 16.5 7.8 23.5 36.6 9.5 11.6 45.2 18.0 14.8 9.2 20.8 12.3 14.4 19.6 11.8 30.4 15.8 52.3 21.1 10.7 9.9 18.9 30.3 33.8 18.0 41.4 12.1 17.1 19.9 16.1 27.7 17.6 13.8 6.8 16.0 14.6 25.5 13.3 13.8 13.9 9.0 22.8 22.8 3.5 11.8 12.6 13.6 5.4 54.4 6.0 18.0 45.8 21.4 21.5 20.3 18.2 47.4 18.5 20.1 19.5 2.3 18.1 25.5 39.4 19.4 36.2 8.6 9.2 8.8 9.7 8.3 8.6 9.2 8.6 9.2 8.6 9.0 9.5 16.6 16.0 30.5 6.2 12.5 12.5 10.4 15.7 55.2 5.1 22.2 31.9 35.4 17.2 21.3 14.7 0.0 9.6 17.8 34.2 78.2 6.4 50.4 13.1 11.6 14.6 19.2 20.8 2.6 9.8 6.0 23.7 34.7 7.8 13.9 10.5 20.0 68.1 30.4 6.7 2.1 50.1 8.2 29.2 13.5 66.1 11.1 35.9 5.4 3.7 33.2 18.1 47.4 4.0 5.0 5.3 22.3 17.3 24.6 11.2 51.8 235.4 23.2 1.8 6.6 13.5 18.1 59.4 1.9 61.6 13.4 3.8 18.1 22.9 71.8 9.0 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 377.4;kidney: 255.9;pancreas: 440.7" "Cell type enhanced" "Detected in many" "Peritubular cells: 1217.5;Proximal enterocytes: 4683.5;Proximal tubular cells: 829.6" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;Hep G2: 33.1;HHSteC: 13.9;U-937: 46.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 370000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.6 2.3 0.0 1.8 0.0 0.4 0.5 0.0 0.2 4.1 0.0 1.7 85.5 0.6 0.9 0.3 0.6 3.9 0.3 0.0 0.3 255.9 0.5 0.9 2.8 0.2 1.1 0.8 440.7 0.0 0.5 0.8 0.6 0.5 0.5 0.3 1.2 1.0 0.0 2.2 377.4 0.3 0.3 4.5 1.6 46.5 0.9 0.9 0.8 0.0 0.9 2.2 0.9 0.0 0.0 0.9 0.2 0.0 1.7 0.2 4.4 0.0 0.0 0.0 0.0 8.5 0.2 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.6 0.0 0.0 33.1 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 1.1 1.1 3.4 0.0 0.0 0.0 3.0 0.0 0.1 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 1.4 0.0 0.0 0.2 0.1 0.0 46.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 1.1 0.6 0.3 0.9 0.0 0.1 3.2 1.8 0.0 9.2 0.5 0.0 0.0 0.0 5.8 1.7 0.0 0.3 0.0 0.6 23.9 0.0 0.2 0.0 2.0 56.7 0.5 13.2 0.2 0.2 7.0 8.9 0.0 0.3 192.1 0.8 8.9 1.1 0.1 1.3 0.7 1.1 0.0 0.5 0.0 0.3 142.3 0.0 0.3 0.3 45.2 289.8 4.8 5.4 0.0 1.0 0.1 0.0 0.0 0.1 27.4 187.4 1217.5 61.2 0.0 4683.5 829.6 0.0 0.2 6.6 0.0 0.7 17.3 2.8 0.0 0.3 0.4 2.5 0.2 151.7 0.0 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 29.9;Kupffer cells: 55.0;Macrophages: 34.6;monocytes: 28.6;NK-cells: 25.7;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 410.0;eosinophil: 841.1;neutrophil: 358.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 841.1" "Cell line enhanced" "Detected in some" "HEL: 4.1;HMC-1: 18.1;NB-4: 4.1;U-937: 6.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.3" HPA035644 Approved NA NA 330000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 6.0 0.9 4.3 12.6 4.4 23.3 2.8 4.3 9.3 2.3 4.1 4.1 3.3 1.4 0.6 1.8 2.8 6.2 2.4 4.1 4.8 1.8 3.8 18.5 18.8 6.3 4.9 0.6 1.0 0.9 0.7 13.4 5.1 1.5 4.1 0.2 1.7 1.2 1.4 1.2 11.9 4.0 5.1 28.6 3.2 2.8 5.6 9.0 2.5 3.3 18.3 8.1 1.3 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 4.1 0.0 0.1 0.0 0.1 18.1 0.0 0.1 0.0 0.0 0.1 0.1 1.3 0.3 0.1 0.0 0.0 0.1 4.1 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.5 0.0 0.0 0.0 0.0 1.0 0.5 0.3 0.0 6.3 0.0 410.0 82.6 841.1 17.0 101.9 19.8 30.3 29.5 13.7 33.0 35.9 34.7 17.8 358.8 44.7 126.7 5.3 31.8 48.9 4.3 4.4 4.3 9.3 4.1 4.8 6.3 4.9 5.1 5.1 5.6 6.6 0.9 0.0 7.9 0.0 20.4 2.0 0.0 0.3 1.2 0.0 0.2 0.3 1.8 0.0 1.7 0.0 0.0 10.0 8.7 0.1 0.0 0.1 0.2 0.1 0.1 4.8 0.0 2.1 0.1 0.0 0.7 1.0 0.5 0.1 2.5 0.0 18.9 0.1 29.9 0.0 0.2 0.0 2.0 55.0 21.0 1.1 0.0 34.6 3.6 10.3 28.6 0.0 25.7 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.0 0.3 8.6 0.0 0.0 0.3 0.8 12.0 9.4 0.1 1.3 54.0 13.1 0.0 0.0 0.1 DPEP3 ENSG00000141096 "Dipeptidase 3" Q9H4B8 16 67975663-67980549 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 47.0" "Group enriched" "Detected in some" 7 "Spermatocytes: 290.4;Spermatogonia: 289.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 6.7;NK-cell: 1.8" "Group enriched" "Detected in many" 8 "granulocytes: 6.7;NK-cells: 1.8" "Cell line enriched" "Detected in single" 10 "U-266/70: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031870, HPA058607" Enhanced NA NA 27000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA031870: AB_2674079, HPA058607: AB_2683775" "unprognostic (9.93e-2)" "unprognostic (2.81e-3)" "unprognostic (1.86e-1)" "unprognostic (9.52e-2)" "unprognostic (3.61e-2)" "unprognostic (1.37e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.49e-3)" "unprognostic (9.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-3)" "unprognostic (1.13e-1)" "unprognostic (3.98e-2)" "unprognostic (1.51e-1)" 0.4 0.1 0.2 0.2 0.2 1.7 0.0 0.2 0.4 0.0 0.4 0.2 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.3 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.3 2.0 0.3 47.0 0.3 0.1 0.0 0.6 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.4 0.2 0.2 0.0 0.0 0.1 0.5 0.5 0.2 6.7 1.8 0.1 0.0 0.0 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.2 0.3 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 20.0 0.0 0.0 0.4 0.0 2.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 41.3 4.4 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.4 0.0 0.0 0.1 0.7 0.0 26.3 0.0 0.0 290.4 289.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 301.3;Hepatocytes: 246.5;Proximal tubular cells: 272.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 51.5 57.3 35.9 12.7 39.2 19.6 52.0 38.6 45.9 46.2 61.6 74.0 59.9 44.9 10.6 57.0 50.7 11.3 189.7 32.1 38.0 123.2 235.7 37.2 13.8 39.1 37.8 38.6 74.7 43.8 50.4 14.6 35.0 56.6 15.0 12.8 78.7 24.2 220.6 49.7 58.8 9.3 37.3 35.3 69.5 18.2 42.0 13.4 105.0 87.8 9.5 50.3 43.6 36.5 29.5 68.0 25.7 107.4 9.6 13.6 96.6 29.5 19.1 23.1 33.7 120.0 88.0 42.3 71.2 17.7 16.9 71.6 29.6 27.5 3.2 74.2 157.1 12.9 61.7 151.7 87.3 38.6 6.0 25.2 63.1 18.9 41.7 16.4 23.6 1.1 71.7 87.1 8.0 119.1 4.0 57.8 60.1 46.8 68.8 134.3 27.7 207.1 45.5 32.5 88.8 56.2 70.0 131.4 92.7 12.6 84.7 67.7 19.6 18.4 68.0 19.9 33.0 95.8 61.0 72.2 23.9 35.4 26.2 1.7 3.6 1.6 1.9 3.8 3.1 4.4 2.8 1.6 3.0 4.9 3.4 2.9 2.0 3.6 2.5 3.6 4.0 0.8 35.9 39.2 38.6 45.9 32.1 38.0 39.1 37.8 35.0 37.3 42.0 36.5 47.1 3.2 28.2 13.4 28.0 21.3 115.6 11.3 21.1 53.2 77.2 95.1 92.3 94.4 15.0 77.3 43.8 179.6 20.5 151.7 301.3 35.1 10.9 128.2 54.8 28.2 45.5 61.7 4.2 36.9 80.7 33.1 33.1 122.8 5.7 62.2 34.2 246.5 47.9 21.9 6.7 105.9 20.3 31.0 23.8 5.3 24.5 29.8 39.2 4.7 17.5 89.9 5.2 13.0 10.0 33.2 91.1 24.0 36.8 72.8 176.1 272.3 14.6 77.6 0.0 73.4 42.7 6.3 19.6 32.9 22.3 109.9 21.7 50.2 104.7 110.5 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 ESCO1 "EFO1, ESO1, KIAA1911" ENSG00000141446 "Establishment of sister chromatid cohesion N-acetyltransferase 1" Q5FWF5 18 21529284-21600884 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042497 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA042497: AB_10794278" "unprognostic (8.12e-2)" "unprognostic (2.90e-2)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.25e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-3)" "unprognostic (1.72e-3)" "unprognostic (6.80e-3)" "unprognostic (9.29e-2)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.72e-2)" 6.0 5.3 5.8 6.1 6.4 16.3 10.4 10.0 8.8 8.0 5.3 6.7 6.3 6.8 10.1 7.5 5.6 5.2 5.7 5.4 7.3 8.0 9.9 5.3 10.1 6.1 6.2 7.4 7.2 10.1 9.0 8.7 6.5 7.2 5.9 7.8 8.0 6.6 10.3 7.8 7.0 4.8 5.9 8.3 6.9 20.2 6.3 11.1 7.3 5.3 9.9 6.9 7.2 7.0 9.3 4.3 9.3 4.7 8.3 8.8 9.6 5.6 10.7 7.9 11.1 8.8 6.3 16.3 12.5 7.1 8.7 13.3 11.6 7.9 10.9 17.1 7.8 12.7 6.1 14.9 13.5 21.3 12.3 7.4 16.6 6.1 15.9 10.4 10.9 11.9 17.7 16.4 10.9 10.7 15.9 22.4 19.3 17.7 9.9 10.2 11.9 18.3 15.7 13.9 14.4 10.3 10.5 13.2 24.3 14.6 9.7 14.4 6.1 10.1 10.2 7.4 7.0 38.8 24.0 18.8 10.0 12.2 10.1 4.9 0.5 3.9 3.3 1.1 2.8 2.2 2.7 3.1 1.1 1.9 2.6 3.3 3.2 2.2 0.9 0.8 3.1 1.0 5.8 6.4 10.0 8.8 5.4 7.3 6.1 6.2 6.5 5.9 6.3 7.0 29.1 12.8 29.5 29.0 35.5 10.7 21.0 24.4 17.1 43.1 22.6 17.4 36.2 10.0 24.2 11.0 20.9 26.0 47.0 15.8 19.6 26.2 14.4 28.6 23.9 18.5 11.4 13.7 48.8 13.4 16.2 20.1 27.5 36.7 29.2 24.4 16.8 7.6 13.7 30.3 55.2 19.4 24.4 9.5 12.4 9.2 21.1 21.3 16.0 31.9 24.1 17.0 46.4 35.7 50.1 18.8 23.6 22.6 31.6 23.5 19.9 15.7 19.7 35.5 26.3 23.1 20.4 119.1 93.6 15.7 12.5 37.6 38.4 37.4 14.1 27.3 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.8;intestine: 53.4;salivary gland: 55.8;skin 1: 56.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 208.5;Intestinal goblet cells: 69.4;Paneth cells: 135.8;Proximal enterocytes: 130.9;Undifferentiated cells: 86.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "RT4: 58.5;SK-BR-3: 19.4;T-47d: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 6: Non-specific - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.6 0.4 5.0 0.5 0.2 9.0 0.7 0.7 7.9 0.4 53.4 44.5 0.4 41.1 53.8 8.5 5.3 0.0 0.5 0.3 39.2 0.4 3.5 0.0 0.5 0.4 0.5 46.8 0.0 0.5 0.0 0.5 6.5 34.0 0.1 55.8 6.4 0.4 56.2 38.4 0.8 0.2 0.1 23.7 0.7 0.4 0.7 0.2 0.0 9.0 18.4 18.8 0.9 3.6 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 6.3 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 58.5 0.2 0.2 0.0 19.4 0.0 0.0 60.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.7 0.7 0.5 0.3 0.5 0.4 0.5 0.2 0.4 0.9 0.1 35.3 6.9 0.0 1.1 4.1 14.7 12.5 5.2 0.0 17.9 11.0 0.2 20.0 38.0 23.9 2.1 0.0 0.3 208.5 21.5 23.8 0.1 7.4 0.3 0.5 6.0 0.0 0.0 38.2 0.0 0.9 24.5 2.6 0.0 0.1 0.4 0.0 0.1 0.0 0.0 69.4 12.2 0.0 1.8 0.2 0.6 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.0 10.6 135.8 0.0 0.0 5.5 130.9 39.5 45.9 0.3 0.0 0.4 2.3 0.0 0.1 30.6 20.9 0.0 1.0 0.0 86.1 26.7 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.9;Inhibitory neurons: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1900000 "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 13.2 13.8 37.0 11.8 35.8 5.5 15.4 43.4 43.8 25.6 53.2 19.1 16.0 19.3 29.1 10.1 21.1 18.2 22.3 38.6 33.3 24.9 16.8 14.4 18.2 34.3 28.9 24.1 27.1 22.9 40.5 13.7 33.6 24.8 14.9 22.7 30.8 22.6 67.5 17.9 20.1 14.9 22.5 15.4 22.1 10.1 32.0 15.8 28.8 13.8 13.6 19.7 18.0 35.4 5.2 7.7 38.5 39.5 29.7 26.4 34.2 21.7 21.9 17.5 26.0 40.6 25.5 0.0 25.1 17.1 17.8 3.6 16.8 9.5 11.5 1.8 29.9 15.9 16.0 21.3 26.5 0.8 24.9 38.5 10.6 19.7 9.1 52.2 1.5 20.3 12.0 2.8 12.2 9.1 4.2 8.1 8.9 9.1 3.8 0.1 26.3 25.9 25.3 7.7 22.4 26.1 11.2 17.6 28.2 14.4 13.5 14.2 0.6 59.8 23.6 5.7 12.6 29.6 4.2 1.9 70.4 1.5 22.4 1.4 2.8 1.5 6.9 2.0 2.0 6.1 5.8 2.6 2.5 5.4 11.5 8.2 0.3 3.0 0.7 1.4 5.1 1.8 37.0 35.8 43.4 43.8 38.6 33.3 34.3 28.9 33.6 22.5 32.0 35.4 2.0 3.2 2.7 23.2 6.4 7.4 18.1 14.8 9.1 40.2 9.6 5.8 1.9 32.9 11.1 18.4 12.5 24.2 2.2 14.2 0.0 16.1 3.2 3.3 7.6 2.1 10.8 1.7 60.9 5.6 12.3 14.0 23.4 4.5 2.5 9.0 1.4 12.1 4.5 40.4 58.0 15.2 38.7 3.2 4.4 1.8 12.5 3.2 10.6 17.8 2.8 9.7 4.1 31.2 25.5 6.3 17.8 7.9 1.9 9.3 11.9 6.1 7.2 19.3 6.6 16.0 9.4 13.9 15.5 5.7 4.3 16.8 7.2 17.0 17.9 13.9 GGTLC1 "dJ831C21.1, dJ831C21.2, GGTLA3, GGTLA4" ENSG00000149435 "Gamma-glutamyltransferase light chain 1" Q9BX51 20 23985050-23988779 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "lung: 32.3;testis: 18.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 137.8;Early spermatids: 45.2;Late spermatids: 130.2;Spermatocytes: 33.6" "Cancer enriched" "Detected in some" 8 "lung cancer: 7.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.0" "HPA045635, HPA047534" Uncertain NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-2)" "unprognostic (5.32e-1)" "unprognostic (4.19e-1)" "unprognostic (1.00e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 32.3 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.5 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 137.8 15.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 45.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 33.6 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 GGTLC2 GGTL4 ENSG00000100121 "Gamma-glutamyltransferase light chain 2" Q14390 22 22644475-22647903 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 18.0" "Group enriched" "Detected in some" 14 "Alveolar cells type 1: 22.4;Early spermatids: 24.6;Late spermatids: 28.4;Spermatocytes: 14.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.6;U-2 OS: 3.3" "HPA045635, HPA047534" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (2.58e-2)" "unprognostic (2.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.96e-1)" "unprognostic (4.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.06e-3)" "unprognostic (1.48e-2)" "unprognostic (1.55e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 18.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.0 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 22.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GGTLC3 ENSG00000274252 "Gamma-glutamyltransferase light chain family member 3" B5MD39 22 18516344-18518161 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 10.5;thyroid gland: 8.2" "Group enriched" "Detected in some" 10 "Alveolar cells type 1: 3.2;Early spermatids: 5.3;Late spermatids: 12.1;Spermatocytes: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SuSa: 1.5;U-2197: 1.0" "HPA045635, HPA047534" Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (1.37e-1)" "unprognostic (2.06e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.5 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 10.5 0.1 2.2 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.2 2.3 0.1 0.0 8.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLYATL3 "bA28H17.2, C6orf140" ENSG00000203972 "Glycine-N-acyltransferase like 3" Q5SZD4 6 49499923-49528078 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 67 "T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044044 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "HPA044044: AB_10960855" "unprognostic (3.57e-1)" "unprognostic (6.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 916.5;kidney: 943.1;liver: 2610.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1652.6;Granulosa cells: 3177.1;Proximal enterocytes: 4294.8;Proximal tubular cells: 3190.6;Theca cells: 4578.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 555.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "Hep G2: 263.9" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 27800000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favorable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" 0.5 916.5 0.0 2.5 0.0 0.0 4.2 0.0 0.2 2.0 0.0 7.3 672.0 0.4 7.0 5.3 86.1 119.5 0.2 0.0 0.0 943.1 2610.5 12.2 0.5 0.0 0.0 78.9 148.6 0.0 0.2 0.5 0.0 18.7 8.1 0.0 21.5 0.6 0.1 1.2 674.6 0.3 0.0 0.2 135.5 336.8 0.3 0.1 0.1 0.0 11.5 2.2 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 19.4 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.5 0.1 263.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.4 2.1 0.0 0.2 1.5 2.1 0.3 0.0 0.0 1.1 0.0 0.2 0.5 0.5 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 6.4 7.7 0.0 13.5 0.0 5.0 35.7 0.0 0.0 7.0 1.5 0.0 453.2 159.9 73.5 0.0 0.1 0.1 5.8 536.1 71.3 11.8 0.4 0.1 3.1 3.0 45.5 0.0 1652.6 0.2 7.3 116.7 0.5 2.5 3177.1 26.4 1013.9 0.1 0.0 0.0 165.6 42.7 31.5 0.0 43.0 65.6 25.3 0.0 0.0 13.3 0.0 1.0 0.0 0.1 629.1 187.4 4.5 0.2 27.6 4294.8 3190.6 533.5 0.0 0.0 0.0 98.6 36.8 3.4 6.8 0.0 0.5 10.4 4578.2 295.3 58.7 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 201.6;Distal tubular cells: 213.2;Exocrine glandular cells: 239.6;Pancreatic endocrine cells: 334.7;Proximal enterocytes: 367.0;Proximal tubular cells: 1186.6;Respiratory ciliated cells: 435.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 25.9;Hep G2: 20.0" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.4 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 149.5 0.0 0.7 0.1 2.5 109.4 0.0 0.0 0.0 696.0 2058.5 4.8 0.1 0.0 0.0 0.2 299.2 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.5 0.0 0.0 0.0 115.5 0.0 0.0 0.0 11.7 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.0 20.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.3 0.6 0.5 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 1.7 0.0 0.2 1.5 0.0 0.0 0.1 0.1 0.0 201.6 31.1 16.5 0.0 0.0 0.0 0.1 213.2 8.1 6.9 0.0 0.0 0.6 0.0 0.0 0.0 239.6 0.2 0.5 7.7 0.0 0.0 37.2 0.7 124.2 0.1 0.0 0.0 13.7 2.0 2.2 0.0 14.6 1.2 5.1 0.0 0.0 5.2 0.0 0.0 0.0 0.1 334.7 18.8 0.4 0.0 3.9 367.0 1186.6 435.5 0.0 0.0 0.0 1.5 1.9 0.7 0.0 0.0 0.0 2.6 10.4 30.1 1.3 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 67.3;fallopian tube: 65.4;placenta: 22.7;skin 1: 26.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 194.9;Syncytiotrophoblasts: 515.3;Theca cells: 91.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.4" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.0 67.3 0.0 0.1 0.1 0.0 1.8 0.0 0.0 1.1 0.5 0.0 0.3 0.8 0.8 0.0 65.4 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.5 0.9 0.1 2.9 0.0 22.7 0.0 0.1 0.0 0.0 0.3 0.2 0.0 26.0 0.4 0.1 0.0 0.0 2.4 11.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.1 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 6.2 0.0 0.0 194.9 0.0 0.0 0.0 0.0 1.3 47.0 0.5 0.5 0.0 0.0 0.0 0.0 7.5 1.1 0.0 0.7 1.3 7.4 0.0 0.4 15.7 0.0 0.0 0.0 2.0 0.0 0.4 2.1 1.5 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 24.8 0.0 0.0 0.0 0.8 0.5 0.5 0.0 9.8 515.3 0.1 91.3 0.0 0.0 GSTA4 ENSG00000170899 "Glutathione S-transferase alpha 4" O15217 6 52977948-52995304 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 295.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 280.0;Granulosa cells: 335.6;Syncytiotrophoblasts: 450.3;Theca cells: 415.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 20.0" "Lineage enriched" "Detected in many" 6 "monocytes: 20.0" "Cell line enhanced" "Detected in many" "AF22: 95.4;ASC TERT1: 93.1" "Low region specificity" "Detected in all" HPA048934 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "HPA048934: AB_2680563" "unprognostic (5.13e-3)" "unprognostic (2.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.38e-1)" "unprognostic (5.24e-2)" "unprognostic (3.63e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-2)" "unprognostic (5.05e-3)" "unprognostic (9.26e-2)" "unprognostic (3.31e-3)" "unprognostic (2.29e-2)" "unprognostic (1.34e-2)" "unprognostic (2.21e-1)" "unprognostic (4.07e-3)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 19.2 295.7 51.2 6.9 52.6 1.7 36.0 55.6 61.0 37.0 37.7 19.2 20.4 27.5 61.2 53.4 24.7 22.9 20.4 53.8 55.5 32.1 34.8 38.7 7.3 44.1 43.5 51.9 31.3 74.4 43.1 48.0 45.2 40.7 24.5 31.2 32.8 28.5 35.9 136.0 19.0 26.2 43.0 13.6 37.2 37.3 48.7 9.9 25.0 36.7 21.4 15.6 40.3 53.8 1.3 10.3 95.4 80.3 56.1 93.1 8.9 13.6 33.7 9.4 16.0 15.6 0.3 1.0 9.1 25.8 10.1 3.9 69.7 13.5 11.8 2.3 29.2 3.3 8.2 54.4 39.8 0.0 2.3 80.1 20.6 12.0 10.1 28.5 59.1 14.1 12.9 15.0 31.9 0.0 1.2 0.3 36.4 58.5 17.3 2.4 41.2 18.6 34.3 1.7 42.2 62.1 0.4 9.9 24.9 48.9 2.5 2.8 28.5 10.0 22.6 9.3 11.6 18.4 2.5 0.5 15.2 1.5 11.0 0.0 0.0 0.0 2.6 0.9 2.0 0.8 0.7 1.2 0.9 2.9 0.5 0.7 0.0 3.2 20.0 1.7 0.8 0.9 51.2 52.6 55.6 61.0 53.8 55.5 44.1 43.5 45.2 43.0 48.7 53.8 15.4 51.3 84.3 22.9 2.2 44.9 22.0 79.0 35.3 39.7 26.1 31.2 10.0 15.7 44.4 27.6 0.0 280.0 3.6 5.6 54.8 14.0 1.4 3.5 24.1 20.0 23.9 9.5 63.4 9.0 108.8 40.5 23.0 4.1 5.7 335.6 31.4 21.1 69.8 37.0 88.2 41.8 57.0 2.5 14.6 9.6 41.7 3.5 96.0 13.1 2.8 70.1 4.1 75.9 62.7 10.8 9.6 39.1 0.8 25.8 12.7 47.7 15.6 11.3 19.7 28.5 36.3 4.7 10.5 96.3 135.5 450.3 3.9 415.9 18.0 21.1 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Smooth muscle cells: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.4 0.0 0.0 0.0 23.6 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favorable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favorable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 150.9 180.9 77.5 135.9 82.5 187.0 159.1 82.7 89.2 154.5 141.0 217.9 317.2 95.2 110.7 154.0 144.7 140.6 271.7 75.7 82.7 257.2 449.3 125.1 185.0 85.2 84.0 71.1 138.0 308.2 79.7 104.2 85.3 111.4 230.8 26.9 213.0 96.4 238.6 132.6 277.1 106.6 79.8 236.5 163.4 85.1 83.3 96.2 160.1 324.1 183.7 129.5 112.4 88.6 150.7 106.1 14.7 130.1 224.2 319.7 68.8 87.0 148.4 76.3 150.8 64.5 375.2 85.4 120.8 126.7 114.5 222.4 57.5 136.2 66.0 165.0 62.3 69.6 80.9 102.9 154.1 84.7 108.4 290.4 164.3 88.0 62.0 113.1 205.3 109.5 99.3 100.9 207.2 116.2 87.3 152.9 34.7 291.3 158.6 73.9 2.4 169.6 266.1 81.6 59.7 81.4 159.4 256.3 137.4 88.3 123.6 117.0 122.2 41.0 37.7 108.5 75.2 171.0 86.5 20.0 148.5 336.0 86.6 351.1 537.1 210.7 298.5 597.9 289.7 254.5 554.6 386.4 445.2 183.2 281.3 274.6 165.0 188.3 641.7 187.0 800.5 917.1 77.5 82.5 82.7 89.2 75.7 82.7 85.2 84.0 85.3 79.8 83.3 88.6 181.9 70.5 95.6 17.0 134.1 114.2 174.9 244.0 118.4 11.6 181.9 198.2 172.9 211.6 219.5 121.4 12.5 295.3 151.4 301.6 291.6 160.5 561.3 102.7 95.8 117.0 153.6 63.3 25.8 120.3 132.0 96.4 185.5 92.9 145.1 47.4 155.3 322.1 304.2 8.4 28.8 252.8 154.6 288.3 174.1 1160.2 72.7 195.8 151.2 16.9 228.5 85.9 194.7 16.6 14.3 104.5 505.2 50.8 130.0 82.9 670.0 620.2 154.0 15.4 85.5 65.9 121.7 6.9 10.3 166.3 116.4 183.7 250.7 150.7 366.5 218.9 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 479.1;liver: 609.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 6.8;Cardiomyocytes: 6.0;Club cells: 6.7;Hepatocytes: 5.5;Kupffer cells: 7.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Region enriched" "Detected in all" 18 "cerebral cortex: 479.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 87.0;HeLa: 96.1;HHSteC: 78.6;hTEC/SVTERT24-B: 73.0;HUVEC TERT2: 62.4;MOLT-4: 115.4;U-266/84: 64.4" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cytokinetic bridge" "CAB022669: , CAB047357: , HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 55.5 155.7 26.1 17.4 26.4 9.7 56.9 24.9 479.1 61.5 26.9 39.1 27.9 38.1 69.6 152.3 45.8 29.4 30.5 25.9 25.8 37.3 609.6 28.2 1.8 25.5 26.3 178.4 66.8 48.7 33.5 8.7 26.1 47.0 22.4 10.2 43.8 128.6 69.3 73.5 47.3 64.3 25.0 63.6 59.5 57.0 26.6 33.5 27.7 0.0 17.9 127.0 135.2 25.3 0.3 0.6 0.3 1.3 0.0 0.0 0.5 0.0 0.3 0.2 0.4 1.0 7.0 26.9 0.1 41.6 0.0 1.3 0.1 0.6 0.7 0.1 0.4 87.0 96.1 1.7 78.6 0.0 0.7 0.1 0.1 73.0 0.3 48.1 62.4 50.1 0.0 56.8 2.5 0.0 115.4 0.7 54.6 0.1 0.0 0.4 0.6 11.1 9.0 0.1 5.3 0.7 0.0 0.3 0.5 2.6 1.1 44.5 0.2 35.5 2.0 0.9 0.1 45.1 64.4 3.7 30.7 1.1 2.0 2.2 26.1 32.2 28.8 39.1 31.0 30.8 31.4 28.5 77.8 32.5 33.1 32.6 2.0 30.1 17.4 41.1 38.9 28.5 26.1 26.4 24.9 479.1 25.9 25.8 25.5 26.3 26.1 25.0 26.6 25.3 0.3 9.6 6.8 0.0 0.2 1.8 0.6 2.0 0.0 0.1 2.7 1.9 6.0 2.8 6.7 0.0 0.0 0.0 0.8 0.4 0.0 1.2 0.0 0.9 1.9 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 2.5 0.0 5.0 5.5 0.1 0.0 0.0 0.3 0.0 7.1 2.2 0.4 3.7 0.5 0.0 0.0 0.7 2.4 0.0 0.0 0.0 0.6 0.1 2.2 0.0 0.1 1.9 0.0 5.1 0.0 0.0 0.3 1.4 0.5 0.4 0.0 1.6 0.0 0.8 0.0 0.2 1.8 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.0;Plasma cells: 28.4;Squamous epithelial cells: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 116.0;HSkMC: 115.6" "Low region specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Supported Vesicles,Cytosol NA NA 1200000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Vesicles "CAB040547: , HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 73.7 84.4 92.3 11.9 109.9 10.7 81.2 86.7 104.6 165.9 111.5 115.2 26.3 70.6 43.7 61.6 102.7 22.0 99.7 93.5 104.7 86.8 35.6 45.2 14.3 94.3 97.1 240.9 54.5 53.6 113.7 9.3 91.9 159.0 17.7 25.1 55.2 80.7 218.4 88.2 65.5 34.2 93.9 52.6 88.3 41.9 105.2 15.9 97.9 108.4 12.6 108.3 144.5 90.6 0.0 3.5 37.8 38.9 44.0 116.0 7.2 24.5 42.6 22.1 28.0 6.7 0.0 0.7 25.5 61.1 18.0 0.2 3.1 0.2 28.6 1.5 0.8 14.0 0.4 9.3 29.6 1.1 25.2 115.6 1.0 32.7 0.0 58.5 16.1 11.6 4.2 0.7 48.5 0.3 19.5 24.6 6.7 0.7 32.4 23.8 0.1 0.2 6.6 0.5 8.1 18.7 0.0 1.0 13.0 21.7 38.6 7.0 0.2 24.3 1.2 35.3 1.9 11.9 19.0 1.3 36.7 0.5 0.3 1.8 3.8 29.6 3.1 6.3 3.1 8.8 8.8 3.4 23.0 6.2 34.4 15.1 2.2 18.0 4.1 29.8 9.4 10.8 92.3 109.9 86.7 104.6 93.5 104.7 94.3 97.1 91.9 93.9 105.2 90.6 2.0 0.0 4.8 16.0 4.5 4.8 2.4 0.9 20.5 1.5 4.5 4.3 61.0 2.8 11.5 3.7 0.0 0.5 6.1 0.4 0.0 0.2 1.9 2.8 10.3 5.8 0.0 10.9 1.5 0.0 0.2 19.2 14.8 2.7 2.5 4.4 1.8 0.8 1.5 3.3 2.6 1.3 2.0 0.8 2.3 10.4 15.5 3.4 5.4 11.2 0.7 7.2 8.2 12.5 0.7 0.1 0.0 10.5 28.4 0.8 0.4 1.2 9.9 0.3 6.6 5.6 13.6 0.3 0.8 27.0 2.8 0.5 5.1 4.0 0.7 1.6 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 377.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 802.2;Early spermatids: 2092.4;Late spermatids: 3843.4;Spermatocytes: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.4;gdT-cell: 3.1;memory CD4 T-cell: 3.9;memory CD8 T-cell: 2.2;naive CD4 T-cell: 7.8;naive CD8 T-cell: 4.3;T-reg: 1.9" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;T-cells: 7.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 228.4;T-47d: 479.6;WM-115: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Approved Cytosol NA NA 790000 "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: AB_2682992" "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 38.7 39.0 56.9 11.0 61.1 3.3 83.5 50.3 69.1 52.7 109.7 45.0 46.8 32.1 243.2 53.6 35.1 47.0 74.8 56.9 63.6 188.1 20.0 23.6 6.2 54.4 54.8 120.4 101.0 41.1 33.7 21.6 55.5 47.5 19.9 21.1 22.6 165.9 65.8 57.2 27.8 58.3 57.5 14.1 76.2 377.9 61.6 13.2 57.9 51.2 7.9 57.1 53.2 58.3 0.2 6.9 49.3 0.1 64.5 39.9 8.5 54.3 9.4 58.2 56.2 21.8 1.9 0.1 30.8 27.8 40.1 2.6 10.0 22.3 80.5 0.3 14.9 50.8 152.1 33.9 69.5 0.0 115.2 40.3 27.0 87.8 0.1 63.5 73.1 61.9 4.7 0.6 26.6 30.0 14.5 1.2 5.3 0.2 93.1 0.4 31.9 2.3 16.3 117.1 86.1 46.0 112.5 228.4 10.5 14.1 479.6 75.3 57.9 0.8 20.9 59.6 36.3 7.7 13.1 0.2 0.6 0.1 186.9 0.3 0.1 3.4 3.1 0.1 0.8 0.3 3.9 2.2 0.1 0.2 7.8 4.3 0.9 0.7 0.1 0.5 1.9 1.5 56.9 61.1 50.3 69.1 56.9 63.6 54.4 54.8 55.5 57.5 61.6 58.3 22.2 6.4 11.5 18.3 7.0 143.5 97.2 104.4 50.1 17.5 196.1 176.8 88.0 50.1 35.9 222.5 6.2 16.3 8.7 17.3 802.2 88.0 2092.4 51.4 40.6 32.9 50.4 33.0 7.5 149.5 9.0 131.6 43.8 93.6 9.5 22.7 58.2 14.2 10.6 15.2 8.0 24.9 28.5 13.9 54.1 3843.4 385.5 15.1 60.5 2.8 3.5 247.5 2.1 14.6 1.7 126.4 32.5 276.1 3.4 53.7 116.9 38.9 5.4 19.2 190.7 23.8 94.4 1177.6 54.4 71.9 107.4 10.3 24.4 121.4 44.1 80.8 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GSTO1 "GSTTLp28, P28" ENSG00000148834 "Glutathione S-transferase omega 1" P78417 10 104235356-104267459 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 657.7" "Cell type enhanced" "Detected in all" "Hofbauer cells: 676.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 1106.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037603, HPA037604" Enhanced NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "HPA037603: AB_2675574, HPA037604: AB_10672283" "prognostic favorable (6.95e-4)" "unprognostic (9.23e-2)" "unprognostic (1.43e-2)" "unprognostic (6.83e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (9.23e-3)" "unprognostic (4.57e-2)" "unprognostic (7.65e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.86e-2)" "unprognostic (1.29e-1)" "unprognostic (5.51e-3)" "unprognostic (5.82e-2)" 95.0 145.4 119.1 102.8 123.1 191.6 89.9 121.3 166.7 90.1 118.0 92.7 167.6 72.0 96.2 79.3 75.4 84.8 277.4 117.3 124.8 154.4 657.7 154.7 93.1 121.3 127.1 83.1 80.5 129.7 102.9 113.6 122.7 80.3 94.8 38.2 75.6 89.6 148.4 63.8 165.2 86.9 122.2 107.1 93.3 14.9 128.8 124.8 82.9 122.5 77.4 109.6 82.6 136.4 287.7 194.5 142.9 249.3 201.4 385.1 62.8 358.3 640.7 237.9 257.2 247.2 292.8 254.2 152.8 245.6 296.8 158.8 97.0 329.2 244.5 128.4 233.7 186.6 122.1 542.7 359.7 241.5 294.5 291.5 136.7 346.3 414.5 331.3 464.1 231.2 394.4 153.4 511.4 159.3 188.3 330.0 130.4 308.1 134.8 136.0 94.9 108.1 358.4 185.1 72.1 88.6 117.6 81.0 1106.0 238.2 92.0 192.7 426.6 276.9 143.6 427.3 328.4 2.7 3.3 2.0 517.7 416.2 112.0 842.8 532.4 157.9 133.0 457.0 164.5 148.8 164.6 172.9 429.3 111.9 143.0 144.3 151.8 185.0 369.1 203.0 204.8 632.1 119.1 123.1 121.3 166.7 117.3 124.8 121.3 127.1 122.7 122.2 128.8 136.4 107.4 76.9 72.6 8.8 64.8 93.7 328.2 297.6 51.2 36.9 63.5 105.5 328.2 218.8 113.3 101.2 20.9 394.2 82.0 101.6 332.6 341.0 22.4 68.1 79.6 164.5 103.5 192.8 12.1 248.4 176.6 173.0 49.5 81.7 146.3 107.6 388.0 628.2 676.5 23.5 11.7 163.8 124.1 321.8 223.6 17.3 114.6 484.5 126.3 8.4 277.7 81.2 95.8 8.5 21.8 347.6 150.7 112.8 39.9 169.4 483.2 538.0 114.3 29.8 151.2 85.3 176.1 5.7 5.1 55.8 78.7 111.0 81.4 224.8 196.6 204.9 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304950 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 133.1;Early spermatids: 314.6;Late spermatids: 442.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 16.9;CAPAN-2: 17.1;hTCEpi: 16.2;hTERT-HME1: 18.3;OE19: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA048141 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA048141: AB_2680281" "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.5 3.5 5.0 0.3 5.7 2.0 5.2 3.4 5.3 4.3 0.4 4.4 2.8 2.2 4.9 11.8 4.3 1.2 0.6 4.4 4.1 14.0 2.8 2.4 0.3 2.2 2.5 5.4 16.7 5.0 14.6 1.0 2.6 8.3 3.1 6.0 7.5 3.2 1.4 14.8 3.5 1.2 1.1 0.5 10.9 35.9 4.3 2.2 7.0 1.3 0.7 3.8 7.5 5.3 10.2 1.4 0.5 0.6 0.6 1.3 1.4 9.6 16.9 4.7 4.9 0.6 17.1 1.6 4.0 0.8 0.5 10.7 0.5 5.3 1.2 1.1 3.2 0.5 3.1 2.4 2.1 0.7 0.7 1.7 16.2 0.3 18.3 1.3 0.8 1.7 1.5 2.9 1.3 12.3 0.1 0.5 1.7 22.1 1.1 0.5 0.7 0.3 4.6 6.5 0.6 1.1 3.3 2.4 2.9 0.8 12.6 0.3 2.4 1.5 5.1 0.6 0.5 2.8 6.4 0.4 1.5 0.8 0.5 0.2 0.1 0.7 0.5 0.2 0.3 0.3 0.5 0.3 0.0 0.5 0.7 0.4 1.7 1.0 0.1 0.3 1.2 0.2 5.0 5.7 3.4 5.3 4.4 4.1 2.2 2.5 2.6 1.1 4.3 5.3 3.6 3.2 21.0 13.1 1.3 34.2 62.1 94.5 50.1 19.0 61.7 78.2 3.0 21.5 46.4 40.5 16.7 14.4 3.8 12.8 133.1 30.6 314.6 26.9 7.6 5.4 54.2 3.6 33.9 63.3 9.9 4.7 31.6 37.6 2.5 3.3 15.7 3.6 1.8 0.0 28.7 34.0 50.8 1.6 3.7 442.8 2.8 2.7 17.8 1.9 2.1 11.1 1.0 24.1 20.1 31.6 29.1 9.8 0.9 25.6 27.1 43.8 31.2 23.0 6.6 3.1 7.4 22.0 8.9 46.0 47.3 6.7 4.3 11.6 40.7 58.0 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2087.9" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 4033.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 4998.3;OE19: 7810.3" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 290.5 276.2 346.8 232.1 370.3 601.3 288.7 358.9 425.7 641.9 695.8 329.6 394.6 331.9 280.3 2087.9 647.5 435.8 367.2 341.4 381.9 567.7 45.1 468.3 321.8 375.7 379.2 306.9 340.9 737.4 320.2 326.9 378.5 291.7 197.1 137.9 541.2 780.4 355.0 731.4 321.7 214.2 367.0 257.2 535.5 45.8 378.1 296.9 579.0 312.5 380.8 526.5 946.2 377.7 1202.5 1599.4 763.7 1198.9 577.8 645.2 705.3 511.3 678.1 761.2 589.3 2956.3 1225.0 3.3 1144.7 813.5 683.7 1707.8 2073.9 2248.5 214.4 848.0 765.3 59.9 1107.6 0.5 852.2 400.3 667.6 807.2 4998.3 609.9 583.3 560.9 1160.2 847.2 1318.2 321.8 605.7 4.3 918.2 1100.6 1475.2 7810.3 681.3 844.8 129.6 3.8 1236.8 3.6 260.6 754.3 719.1 230.9 2394.0 598.2 3.6 656.3 634.5 351.6 883.8 740.6 378.6 200.0 1353.9 447.1 400.0 652.4 747.8 56.0 3145.4 246.6 720.0 2470.8 271.9 509.2 322.4 597.7 3582.7 476.3 267.8 466.5 130.5 1443.8 1608.5 1435.1 363.3 3948.4 346.8 370.3 358.9 425.7 341.4 381.9 375.7 379.2 378.5 367.0 378.1 377.7 466.7 1153.8 872.3 25.5 296.8 865.6 1914.8 3813.8 767.2 170.0 628.7 838.3 297.3 987.9 2763.5 1230.4 33.3 2116.8 372.4 655.0 1805.9 1811.9 4.9 1381.0 589.0 431.4 368.2 166.3 6.8 1444.4 1703.9 710.5 781.9 1020.9 269.9 795.0 382.3 10.5 861.2 70.7 10.1 992.4 1930.7 597.9 1090.3 25.5 572.3 703.5 1531.5 27.2 2166.5 558.5 459.3 17.6 38.4 1412.1 948.9 400.2 591.6 2266.2 844.4 3495.5 3715.4 274.4 361.6 401.3 941.7 4.8 54.9 4033.7 1061.7 1645.5 342.5 527.8 1118.5 3418.6 GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B" P0CG30 22 23957414-23961195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 81.8;breast: 307.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Hepatocytes: 27.6;Muller glia cells: 20.9;Peritubular cells: 28.6;Skeletal myocytes: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 57.0;HHSteC: 81.9;SK-MEL-30: 60.3;T-47d: 64.8" HPA000750 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA000750: AB_1849804" "prognostic favorable (5.06e-4)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (4.51e-2)" "unprognostic (7.13e-2)" "unprognostic (8.41e-3)" "unprognostic (2.58e-1)" "unprognostic (7.99e-2)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (4.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-2)" "unprognostic (2.19e-3)" 12.3 81.8 21.6 4.3 21.5 0.0 307.9 21.4 27.0 16.6 19.5 17.2 1.4 15.5 12.0 24.7 16.1 5.5 23.9 20.8 22.7 15.2 39.5 18.5 1.8 22.2 22.2 22.6 26.1 6.4 26.0 4.4 22.2 40.6 1.9 3.8 12.5 10.4 16.4 47.8 8.3 11.8 21.0 10.2 23.8 5.5 24.3 1.8 18.6 41.0 1.6 12.1 14.0 21.1 17.0 0.8 0.0 57.0 1.0 1.1 2.4 8.0 4.7 11.5 11.9 24.8 0.2 0.0 12.9 20.2 29.7 24.5 0.0 25.5 5.2 0.0 2.2 0.9 33.6 4.0 81.9 0.1 9.1 33.4 4.0 33.2 6.7 32.6 9.6 0.0 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.9 12.5 0.0 42.4 0.1 26.0 0.0 1.1 23.8 8.2 0.2 60.3 0.2 64.8 0.9 32.0 9.9 6.5 1.3 6.4 0.0 0.0 0.1 6.1 0.0 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 21.5 21.4 27.0 20.8 22.7 22.2 22.2 22.2 21.0 24.3 21.1 8.1 3.2 3.6 1.3 0.9 0.0 8.6 0.0 2.8 3.9 9.4 17.9 0.2 7.2 1.3 0.0 0.0 1.6 0.1 0.0 29.4 7.9 0.6 1.3 11.8 7.1 1.2 5.3 2.4 9.1 3.5 7.6 1.1 2.9 1.3 2.2 18.5 27.6 10.5 0.0 2.1 0.4 0.0 3.8 0.0 1.5 9.9 1.5 0.0 0.0 3.2 20.9 0.0 2.0 0.7 4.2 0.0 28.6 0.7 7.9 0.0 5.7 0.0 2.8 6.6 26.7 9.6 0.4 0.7 0.9 0.0 1.8 0.2 0.4 0.1 3.8 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 263.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 373.2;Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 182.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 340000 "Cluster 18: Basophils - Vesicular transport" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 13.9 34.7 11.1 9.7 12.5 9.3 23.2 13.2 16.3 12.7 10.5 21.9 22.5 10.8 22.1 26.9 14.9 11.9 14.3 10.5 12.3 24.5 263.1 7.8 13.5 12.6 11.7 6.5 20.1 26.4 13.3 11.2 12.8 21.1 21.7 5.1 24.1 9.6 47.4 22.1 15.6 7.9 12.3 12.1 18.9 57.8 11.9 14.0 19.5 37.3 17.4 11.9 13.8 14.0 18.8 39.0 27.6 19.9 17.1 23.9 45.8 11.4 11.9 21.6 30.9 13.0 45.2 43.5 14.9 13.6 13.4 24.1 18.9 22.5 20.7 23.2 21.0 20.8 13.3 26.9 26.3 7.8 15.8 22.1 24.0 12.4 20.8 12.0 18.6 24.7 17.5 37.0 14.5 182.1 12.2 16.4 8.2 64.1 30.3 20.2 29.5 34.2 32.5 24.0 30.2 26.2 26.0 49.1 35.6 15.5 81.2 11.1 13.8 17.0 52.5 18.9 8.6 28.2 32.7 35.2 41.9 11.3 20.8 13.4 15.5 9.9 2.6 22.2 2.4 8.2 4.6 3.7 20.7 10.4 3.9 3.1 1.6 5.1 20.1 15.0 7.9 7.4 11.1 12.5 13.2 16.3 10.5 12.3 12.6 11.7 12.8 12.3 11.9 14.0 6.1 6.4 9.6 6.5 13.5 13.4 19.8 26.2 15.9 7.3 36.1 34.2 13.0 47.1 19.0 9.2 4.2 91.4 7.5 34.9 46.9 45.0 125.8 19.4 15.6 11.1 28.8 30.3 2.9 68.0 62.5 15.0 33.1 27.0 3.8 25.7 15.4 373.2 44.6 16.8 3.3 45.7 20.3 38.1 10.9 398.1 11.8 19.0 17.8 3.7 30.4 26.4 4.1 2.0 9.2 41.8 37.4 6.0 13.2 19.8 72.9 77.8 15.0 11.9 0.0 12.3 13.2 51.3 29.4 38.0 14.1 76.2 6.7 55.8 50.3 30.3 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.8;Excitatory neurons: 47.7;Microglial cells: 20.6;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 13.6;LHCN-M2: 11.6;RH-30: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" 2.1 6.5 1.1 0.6 1.1 0.4 3.3 0.3 1.6 3.4 3.6 2.3 1.1 2.5 3.1 2.8 2.8 2.2 2.4 1.0 0.4 4.0 2.7 2.1 0.8 0.7 0.8 2.1 2.3 1.7 3.2 1.3 0.6 4.0 1.3 1.7 4.4 2.0 0.3 3.4 2.5 1.1 0.9 2.2 1.8 2.5 0.6 2.0 4.6 0.2 0.8 3.1 2.9 0.9 0.8 0.9 2.3 1.3 1.0 1.3 4.8 1.2 1.1 1.9 3.1 0.2 0.9 0.0 1.2 0.9 3.1 0.6 0.5 0.5 2.2 1.7 1.2 0.0 0.1 1.1 0.2 0.3 13.6 1.2 2.7 1.6 1.2 3.2 0.3 1.2 0.0 0.0 11.6 1.2 0.6 0.0 0.6 0.7 0.1 1.3 12.4 0.0 7.5 2.6 1.9 7.8 2.1 0.0 6.0 5.9 4.0 0.7 1.7 2.8 8.5 1.6 4.7 3.8 0.2 0.0 1.1 0.8 2.3 0.0 0.3 0.0 0.7 0.4 1.3 1.5 0.9 0.8 0.4 1.8 0.0 0.2 0.0 0.1 0.1 3.7 0.2 0.4 1.1 1.1 0.3 1.6 1.0 0.4 0.7 0.8 0.6 0.9 0.6 0.9 2.0 0.0 2.4 25.8 5.3 2.2 5.7 2.8 6.8 0.5 5.8 2.4 2.4 4.3 1.2 9.2 0.0 4.6 13.9 1.9 3.9 2.6 1.2 8.8 2.6 2.0 0.0 0.4 47.7 0.7 3.6 3.0 2.6 5.8 0.0 4.6 3.6 2.5 1.9 0.0 11.8 2.7 4.1 2.9 0.5 0.5 1.2 1.5 0.0 20.6 1.0 15.6 0.0 17.1 26.0 1.2 2.1 0.4 2.2 3.7 2.3 0.6 12.9 0.5 0.0 1.7 1.7 0.3 1.3 3.1 2.6 2.2 2.8 0.4 2.0 5.2 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Group enriched" "Detected in many" 18 "granulocytes: 1056.2;Hofbauer cells: 631.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 18.1" "Lineage enriched" "Detected in single" 28 "granulocytes: 18.1" "Group enriched" "Detected in some" 8 "HEL: 46.2;HMC-1: 13.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 250000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 3.4 1.9 2.2 1.1 2.1 1.1 4.0 2.3 3.1 3.5 2.1 5.1 5.8 2.4 2.3 2.9 1.4 6.9 1.8 2.3 2.3 1.5 0.8 9.4 0.6 2.7 2.6 0.5 0.5 0.8 0.4 18.7 2.9 2.6 5.3 0.1 1.5 1.3 0.5 3.3 5.6 3.3 2.6 0.3 2.8 0.7 3.1 2.0 0.3 1.7 0.9 4.8 1.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.2 0.0 0.0 0.0 3.5 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 2.2 2.1 2.3 3.1 2.3 2.3 2.7 2.6 2.9 2.6 3.1 3.5 0.3 12.8 44.7 1.0 0.2 4.1 0.8 0.0 0.6 0.0 0.2 0.8 0.3 0.0 3.7 0.0 0.0 3.6 0.7 0.5 0.0 0.5 0.1 0.2 0.0 2.0 7.1 12.2 0.8 0.0 3.0 3.0 3.6 0.0 1056.2 0.0 0.0 0.0 631.9 0.0 0.6 0.0 0.0 11.4 13.1 0.0 0.3 16.3 3.6 32.8 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.4 2.1 3.9 0.0 0.0 1.5 0.1 0.0 0.6 0.4 0.0 0.1 0.0 5.4 5.5 20.5 0.3 0.9 0.2 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 191.3;Distal enterocytes: 476.1;Intestinal goblet cells: 288.8;Paneth cells: 226.2;Proximal enterocytes: 270.2;Syncytiotrophoblasts: 114.5;Undifferentiated cells: 170.9" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 11.4;OE19: 29.0;RPMI-8226: 13.9;RT4: 13.9;SCLC-21H: 14.9;SK-BR-3: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 2.1 5.4 1.6 13.4 4.6 0.1 14.0 2.8 2.8 15.5 0.7 249.9 40.0 11.8 4.0 10.9 10.4 6.8 1.9 1.6 1.3 335.2 5.5 3.2 1.0 2.7 1.3 9.3 7.4 3.6 0.5 13.0 3.3 12.9 102.2 0.0 260.2 6.2 0.9 66.1 141.8 18.3 1.5 7.0 9.8 2.5 2.0 0.4 11.1 0.2 0.9 5.3 23.6 2.4 3.6 1.1 0.4 1.4 0.1 1.7 3.6 0.0 0.0 0.1 0.1 6.1 1.3 0.0 2.7 0.1 0.1 7.8 5.1 0.5 0.0 0.0 1.8 0.0 0.7 6.6 0.6 0.7 0.0 1.7 3.0 0.3 0.1 0.0 0.0 4.6 0.4 0.0 0.0 3.8 0.2 0.2 11.4 29.0 1.0 0.0 0.2 13.9 0.5 13.9 14.9 1.0 0.8 13.4 0.6 1.3 6.5 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.6 2.8 2.8 1.6 1.3 2.7 1.3 3.3 1.5 2.0 2.4 0.7 0.0 0.5 0.0 1.1 1.5 7.2 1.3 1.2 0.0 4.8 2.2 0.5 30.0 2.3 191.3 0.0 1.2 0.3 476.1 45.0 2.1 0.2 17.4 25.2 0.5 26.9 0.0 1.1 3.0 0.7 7.1 7.1 43.5 8.9 43.4 1.1 1.2 1.4 0.0 0.8 288.8 4.1 0.3 0.5 0.5 25.4 0.7 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.6 226.2 6.8 0.2 13.5 270.2 16.3 0.4 0.0 13.1 0.3 3.9 0.2 1.6 3.5 3.4 114.5 1.2 16.7 170.9 10.5 HSD17B10 "17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1" ENSG00000072506 "Hydroxysteroid 17-beta dehydrogenase 10" Q99714 X 53431258-53434370 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, tRNA processing" Oxidoreductase "Disease variant, FDA approved drug targets, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 444.0;Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001432 Approved NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA001432: AB_1078740" "unprognostic (1.27e-1)" "prognostic favorable (2.80e-4)" "unprognostic (2.60e-1)" "unprognostic (2.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-1)" "unprognostic (8.64e-3)" "unprognostic (4.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.95e-2)" "unprognostic (8.38e-2)" "unprognostic (3.07e-3)" "unprognostic (2.92e-1)" "unprognostic (9.51e-2)" 71.1 110.7 63.5 52.5 67.5 64.8 62.7 70.0 64.7 58.1 64.6 62.8 58.0 62.0 56.2 111.6 55.4 33.4 103.8 62.0 68.4 99.1 261.3 48.4 59.4 70.4 68.2 67.1 74.8 73.4 66.1 37.2 67.8 50.7 62.9 12.7 55.0 46.0 90.5 90.0 50.3 62.0 66.6 52.0 66.4 21.5 69.1 60.1 66.4 81.6 76.3 56.3 59.8 69.2 121.9 203.1 97.2 181.3 93.4 41.0 146.5 73.7 72.9 192.0 125.3 210.3 101.8 205.8 65.6 84.9 124.2 124.5 316.1 148.7 104.3 164.1 177.7 97.1 283.6 177.0 156.3 185.1 145.5 87.6 138.9 148.7 82.8 41.6 142.2 181.2 141.6 158.1 90.3 426.7 165.3 277.0 269.9 163.0 259.5 166.2 179.2 364.9 149.3 132.2 171.1 225.1 211.7 250.2 138.6 123.0 263.3 169.8 64.2 81.7 129.7 171.9 113.4 128.3 194.1 256.5 113.4 384.9 123.2 54.2 127.8 40.4 84.8 125.1 87.2 98.8 78.0 84.1 176.7 111.4 64.4 67.9 10.5 98.7 94.5 96.5 114.8 126.6 63.5 67.5 70.0 64.7 62.0 68.4 70.4 68.2 67.8 66.6 69.1 69.2 42.8 48.1 37.3 4.9 61.8 86.4 90.2 150.8 44.9 11.8 72.5 74.9 62.0 107.2 70.2 101.2 4.2 173.2 55.0 73.8 283.7 131.5 1.6 26.1 64.7 58.3 104.6 71.3 2.5 135.4 228.1 72.0 28.1 51.9 56.5 75.3 56.4 444.0 136.8 13.5 3.3 78.2 99.7 73.9 98.6 5.7 78.3 65.4 96.0 3.7 118.7 61.3 89.6 6.6 6.2 101.9 54.1 94.8 83.3 74.6 78.5 427.8 31.5 13.2 78.9 63.1 117.9 23.6 56.3 91.3 116.2 151.6 62.4 104.1 103.0 83.7 HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 288.6;liver: 241.6" "Cell type enhanced" "Detected in all" "Paneth cells: 498.6;Proximal enterocytes: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 768.7" "Group enriched" "Detected in all" 4 "granulocytes: 768.7;monocytes: 202.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 295.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" 56.0 64.1 15.0 33.0 15.7 109.9 45.5 19.7 18.6 44.0 18.8 139.6 216.7 57.5 28.2 21.5 44.2 107.7 21.0 15.6 18.4 75.9 241.6 104.4 41.5 20.1 17.5 60.6 54.5 10.9 13.1 47.2 18.9 25.5 145.8 8.2 14.8 34.2 12.1 14.5 288.6 49.4 19.3 42.7 36.6 10.1 16.7 36.3 19.3 26.3 34.9 41.8 33.5 22.8 1.0 45.4 22.2 56.1 66.5 92.4 31.2 23.4 39.3 16.1 29.9 38.2 295.2 0.0 45.8 26.2 14.8 0.9 65.6 5.2 18.0 72.1 13.8 63.3 22.9 131.0 37.6 114.8 114.0 65.3 1.7 22.5 7.4 51.3 31.5 27.4 67.9 32.7 30.1 1.8 24.0 144.8 37.8 146.7 7.6 63.2 20.4 77.7 45.5 70.0 7.2 69.3 47.5 1.6 87.0 28.2 0.1 112.7 24.9 11.0 47.9 43.1 13.0 15.0 6.6 7.1 20.1 80.6 77.0 591.1 202.0 442.9 62.5 142.7 74.8 57.1 62.6 64.6 108.2 47.6 55.8 64.2 768.7 82.3 125.8 36.8 77.4 171.6 15.0 15.7 19.7 18.6 15.6 18.4 20.1 17.5 18.9 19.3 16.7 22.8 169.0 314.1 179.5 13.4 89.0 28.0 77.0 16.0 10.8 1.8 5.0 6.2 5.3 368.9 83.7 44.1 2.1 30.6 63.1 356.8 25.4 53.9 1.2 9.0 28.1 101.8 93.7 68.8 16.8 58.6 59.7 77.3 28.1 18.8 100.1 34.1 112.5 337.3 129.1 18.5 14.7 180.8 18.3 220.4 176.2 5.1 104.1 139.1 67.6 43.1 197.3 36.3 113.3 16.6 19.0 65.9 498.6 59.5 60.8 39.5 1134.9 173.6 62.2 3.9 72.3 77.9 43.0 2.7 15.4 10.4 21.5 14.9 93.8 65.4 281.0 93.9 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 60.9 65.4 42.0 31.4 50.4 25.1 48.8 58.1 63.0 51.3 71.5 65.8 67.3 37.4 50.6 36.3 41.3 35.6 69.5 42.0 54.3 91.3 122.9 51.4 28.5 58.8 52.1 45.3 43.5 134.3 28.5 41.6 58.9 52.8 59.5 47.0 46.9 41.5 27.8 30.0 41.7 48.6 52.8 34.8 56.1 33.5 48.9 22.3 66.8 51.6 32.3 31.4 26.8 61.9 40.2 64.3 68.4 69.6 226.8 211.5 45.0 96.7 97.8 67.3 73.0 75.7 80.7 97.4 69.4 91.5 111.7 151.6 48.7 125.5 82.6 19.0 89.2 46.4 28.3 66.2 114.6 132.3 125.4 131.1 93.6 68.1 193.6 85.9 96.1 60.4 43.9 157.9 59.4 22.9 38.6 63.1 126.0 49.9 45.3 63.9 102.3 110.8 129.5 95.9 24.5 56.5 132.0 110.7 100.2 64.6 80.2 112.5 92.4 73.9 28.3 189.3 117.6 81.6 110.3 58.3 78.5 25.0 55.4 8.8 13.4 7.0 12.1 14.8 13.5 12.7 9.6 10.5 21.3 15.2 15.6 13.9 11.2 16.4 8.2 18.4 6.2 11.6 42.0 50.4 58.1 63.0 42.0 54.3 58.8 52.1 58.9 52.8 48.9 61.9 73.6 64.1 111.1 96.6 45.4 31.7 47.1 92.8 57.5 77.1 46.1 36.4 80.7 74.4 81.4 51.5 77.2 60.4 30.6 82.2 27.4 100.2 61.8 36.9 47.5 70.9 138.2 40.8 126.9 82.3 42.1 59.7 60.6 37.0 155.9 37.3 76.1 214.0 63.5 121.1 155.6 75.5 87.5 50.9 43.7 24.1 34.2 45.3 39.2 59.0 37.2 128.2 30.9 128.7 97.5 71.4 62.5 56.8 61.4 61.3 54.2 50.1 75.8 67.8 78.9 45.4 60.2 17.5 14.5 66.0 45.7 74.8 29.4 95.5 115.5 48.6 HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" 9.2 39.5 38.1 3.2 36.3 1.2 11.2 42.8 47.7 34.1 72.5 10.5 3.3 31.6 5.6 4.2 22.7 11.6 8.1 37.2 38.2 58.2 78.8 13.1 8.0 35.6 41.2 56.2 6.2 46.7 24.1 7.3 35.3 15.0 1.9 10.0 6.4 9.2 1.3 7.7 8.2 8.5 35.8 8.7 8.6 4.8 43.6 9.6 25.3 2.2 3.8 15.8 14.6 37.0 0.1 14.0 14.1 2.4 15.8 2.6 0.3 2.6 19.9 1.1 1.2 13.4 0.2 8.0 14.2 0.6 53.9 0.1 1.3 0.1 1.3 0.5 1.0 4.1 0.3 1.8 49.5 0.0 20.9 19.0 0.5 1.2 0.5 37.9 18.1 4.8 0.1 50.7 0.1 0.5 1.1 0.4 1.2 8.2 9.3 7.9 0.1 1.5 0.0 40.5 3.5 9.0 0.0 1.8 10.9 6.0 0.4 0.5 0.0 0.3 5.2 0.5 0.1 8.9 18.9 0.6 11.9 1.2 0.1 0.0 0.0 0.0 0.9 0.0 1.5 3.7 1.5 0.7 0.0 2.5 3.1 2.3 0.0 4.7 0.0 0.5 0.5 0.8 38.1 36.3 42.8 47.7 37.2 38.2 35.6 41.2 35.3 35.8 43.6 37.0 3.3 3.2 11.5 21.5 6.0 2.5 3.6 1.7 0.0 5.5 1.3 5.0 2.0 1.5 4.4 7.3 0.0 1.4 0.3 0.0 78.2 1.9 0.4 0.3 3.5 8.2 13.2 5.3 5.0 1.1 3.0 14.1 2.0 0.7 7.0 7.4 28.5 32.0 149.9 11.8 5.0 0.3 8.2 13.4 9.5 1.4 4.1 17.3 21.4 6.5 8.0 53.5 1.0 4.5 0.8 2.6 0.0 7.2 0.1 3.8 2.2 434.5 0.7 1.6 0.0 2.4 2.9 5.6 15.7 0.3 1.8 2.2 2.8 7.5 0.2 2.9 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 42.5;Hepatocytes: 68.9;Hofbauer cells: 53.9;Proximal enterocytes: 45.3;Proximal tubular cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Cell line enhanced" "Detected in many" "HDLM-2: 91.0;Hep G2: 66.2;HMC-1: 98.1;U-2197: 96.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" 27.3 25.7 5.7 10.9 6.2 4.4 17.1 14.7 9.1 8.5 3.5 15.9 19.5 9.5 2.1 12.3 9.4 11.5 11.7 5.9 5.9 27.7 136.5 11.2 8.4 6.3 5.4 8.6 25.6 8.0 5.4 4.5 6.6 8.2 5.8 1.6 10.0 4.5 7.0 18.5 18.4 9.8 5.6 16.3 11.1 6.0 7.1 2.8 6.3 4.5 5.5 13.9 8.7 6.9 20.3 23.2 2.4 11.5 7.9 28.5 1.4 24.8 38.7 4.8 10.0 1.7 34.4 1.2 8.1 30.3 0.8 6.1 2.2 3.6 2.4 91.0 5.4 1.6 18.6 66.2 7.4 0.5 98.1 13.7 6.0 23.1 4.6 11.2 2.2 1.2 4.9 1.0 18.3 43.6 0.6 14.4 1.9 8.5 3.2 2.5 7.8 22.3 15.1 1.3 8.4 4.1 3.2 15.9 2.2 1.1 31.1 1.6 11.5 10.0 2.8 96.1 2.7 1.6 15.4 1.1 39.1 2.5 0.8 61.8 1.4 27.3 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.2 0.0 0.1 1.2 0.5 0.0 0.6 0.0 0.7 5.7 6.2 14.7 9.1 5.9 5.9 6.3 5.4 6.6 5.6 7.1 6.9 7.6 3.2 4.2 3.3 1.2 7.9 2.6 4.1 4.0 0.7 13.6 9.8 1.7 27.1 2.2 14.7 0.0 2.0 0.5 10.8 15.6 42.5 37.5 1.9 7.1 11.1 7.8 4.8 0.2 30.3 3.5 26.0 8.2 4.2 9.5 9.0 6.8 68.9 53.9 1.7 0.4 11.4 6.1 7.3 15.9 2.2 6.5 11.4 14.2 0.0 12.8 2.1 0.0 0.5 1.2 20.7 14.0 5.3 1.9 1.8 45.3 46.7 1.3 0.5 13.1 9.4 6.3 0.8 1.2 4.9 12.6 1.4 1.7 6.5 23.5 2.8 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.3;Inhibitory neurons: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: AB_2680678" "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavorable (9.67e-4)" "prognostic unfavorable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" 4.2 4.9 6.1 5.0 6.7 9.9 5.3 10.8 9.3 6.7 3.4 7.8 12.3 7.2 9.8 5.1 6.1 6.2 11.3 5.3 7.8 9.5 8.6 5.1 5.4 2.9 3.3 4.9 5.9 6.3 3.2 4.3 3.1 7.8 7.9 10.6 4.6 7.0 9.6 6.6 9.5 8.7 0.8 5.3 5.3 8.3 7.0 6.4 10.9 4.1 5.4 4.9 3.7 10.2 16.9 21.6 11.3 19.3 2.6 5.7 16.3 11.8 11.7 12.3 10.3 21.8 19.0 10.5 10.7 18.4 15.2 18.3 38.8 16.0 12.1 13.6 13.0 19.4 12.8 21.6 12.0 28.1 14.3 4.6 12.4 13.0 18.0 8.0 8.7 6.0 18.3 9.5 9.6 12.8 16.1 16.5 12.5 13.6 12.4 15.6 22.9 21.8 9.7 24.7 13.1 20.5 26.4 17.4 15.7 7.7 12.6 9.5 10.0 22.1 18.2 12.4 18.9 7.0 16.2 23.2 22.7 20.1 17.3 15.9 2.3 5.0 5.2 3.8 6.2 7.5 8.3 6.7 2.8 9.7 11.7 11.5 7.2 4.6 3.6 2.0 4.2 3.0 6.1 6.7 10.8 9.3 5.3 7.8 2.9 3.3 3.1 0.8 7.0 10.2 6.5 9.6 6.9 27.1 11.4 7.1 5.0 8.4 6.8 15.5 6.9 5.3 20.1 18.6 8.7 14.7 27.1 5.2 6.7 10.4 0.0 7.7 3.9 12.0 7.0 7.7 13.1 10.3 67.3 16.4 5.3 6.7 3.1 9.4 3.8 11.6 8.6 21.5 6.1 15.2 86.8 14.3 0.0 5.7 3.9 1.4 5.6 3.4 5.4 45.0 2.4 7.9 5.2 50.8 37.3 12.9 8.6 9.1 5.2 5.4 21.4 12.1 16.6 18.2 6.6 10.9 16.3 13.9 21.0 7.9 6.7 1.9 9.1 10.9 17.0 4.7 LIPT1 "MGC12290, MGC13378" ENSG00000144182 "Lipoyltransferase 1" Q9Y234 2 99154955-99163157 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 41.0;Spermatocytes: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034802 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034802: AB_10669851" "unprognostic (1.13e-2)" "unprognostic (7.21e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-2)" "unprognostic (7.46e-2)" "unprognostic (6.48e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.70e-4)" "unprognostic (1.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.32e-3)" "unprognostic (1.72e-1)" "unprognostic (4.92e-2)" "unprognostic (3.16e-1)" "prognostic favorable (9.60e-8)" 7.1 7.8 6.7 6.8 7.5 12.3 10.9 7.4 8.3 8.1 6.3 6.7 8.4 8.1 14.1 5.1 8.1 6.5 8.5 6.9 7.8 11.2 8.1 5.7 10.7 7.2 7.1 11.8 7.3 6.3 6.7 4.9 7.2 9.2 7.3 7.5 8.9 6.0 9.1 7.0 8.4 5.6 7.2 11.9 6.9 13.5 7.2 5.3 11.3 8.9 7.4 6.3 5.6 10.4 6.2 4.0 5.4 9.2 9.3 11.0 13.0 4.0 4.7 3.1 3.4 9.8 10.3 9.9 8.4 2.4 8.4 5.4 6.6 5.0 6.1 10.6 12.0 10.3 5.1 8.7 9.9 7.0 5.1 6.5 8.0 5.6 12.7 6.3 8.8 11.4 10.0 5.8 5.4 5.0 6.9 13.4 13.8 6.0 9.9 11.7 5.8 10.4 10.1 9.2 5.2 5.0 5.6 6.2 14.8 9.8 6.6 14.2 6.4 4.6 6.4 4.1 3.8 9.1 12.9 10.7 4.8 11.4 6.7 15.4 10.3 16.1 16.8 9.6 20.9 14.2 18.9 18.5 5.6 12.4 23.6 19.9 2.7 18.4 9.5 5.6 12.3 11.6 6.7 7.5 7.4 8.3 6.9 7.8 7.2 7.1 7.2 7.2 7.2 10.4 9.3 3.2 6.7 6.5 7.5 3.6 10.8 14.5 6.2 5.2 3.9 7.9 6.6 2.8 8.5 12.9 2.1 7.6 9.7 3.3 13.7 5.1 41.0 3.6 6.5 7.8 6.1 3.2 5.3 3.4 4.3 7.2 3.1 3.4 5.1 8.3 12.8 2.2 7.2 11.8 5.5 6.1 6.1 7.9 2.2 25.4 9.6 4.6 1.8 1.9 8.5 12.1 18.6 9.5 14.3 3.4 6.9 7.5 2.7 5.6 15.9 11.8 9.0 10.6 6.6 13.1 5.8 40.6 12.8 3.0 4.3 5.3 8.9 5.0 6.2 6.2 LPCAT1 "AGPAT10, AGPAT9, AYTL2, FLJ12443" ENSG00000153395 "Lysophosphatidylcholine acyltransferase 1" Q8NF37 5 1456480-1523962 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.3;lymphoid tissue: 38.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 324.0;Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 148.2" "Cancer enhanced" "Detected in all" "lung cancer: 79.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 89.1;EFO-21: 82.4;PC-3: 60.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012501, HPA022268" Enhanced Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "Lipid droplets" "HPA012501: AB_1845224, HPA022268: AB_1845225" "unprognostic (5.33e-3)" "prognostic unfavorable (7.11e-5)" "unprognostic (3.11e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (3.13e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.88e-8)" "unprognostic (5.90e-2)" "unprognostic (6.37e-2)" "unprognostic (2.08e-2)" "prognostic favorable (4.90e-5)" "unprognostic (4.89e-2)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.60e-1)" "unprognostic (3.13e-1)" "unprognostic (1.52e-1)" "unprognostic (4.03e-1)" 11.1 9.4 3.4 2.4 3.5 1.4 8.4 0.6 13.3 10.6 3.2 8.8 0.8 12.4 0.1 4.6 10.8 0.8 7.7 6.0 8.3 6.1 3.9 57.3 1.6 3.3 5.0 8.6 5.1 0.6 10.0 1.4 6.3 6.8 0.1 2.1 8.3 0.8 2.5 5.0 11.2 0.4 2.3 38.2 6.9 2.8 5.1 0.5 7.3 0.0 0.3 11.5 7.0 1.0 5.5 8.1 1.5 8.6 1.0 1.3 89.1 19.2 1.1 1.0 0.9 3.1 2.6 17.7 82.4 0.5 3.8 15.7 1.7 0.5 0.5 41.5 36.1 4.4 12.7 5.8 1.7 4.7 11.8 1.5 0.4 1.0 0.2 1.3 1.1 6.2 9.8 3.5 0.0 11.8 17.3 7.3 31.2 0.5 60.7 32.2 1.5 13.7 3.6 7.5 11.5 11.1 16.5 14.8 5.1 0.9 6.9 7.4 9.8 1.6 19.0 6.1 7.3 10.9 11.0 4.4 3.7 7.7 5.5 0.0 0.2 0.2 1.1 0.5 1.1 0.2 0.2 0.5 0.1 0.1 0.0 0.3 0.8 0.5 0.4 0.0 0.2 0.2 3.4 3.5 0.6 13.3 6.0 8.3 3.3 5.0 6.3 2.3 5.1 1.0 12.6 86.6 324.0 18.9 41.9 6.2 2.5 5.3 6.8 65.8 8.9 6.3 4.0 5.7 14.4 14.7 146.0 9.0 97.4 6.7 0.0 22.4 1.7 4.8 13.7 13.5 14.9 3.6 13.9 13.6 81.9 13.1 7.1 5.2 8.2 44.7 16.4 5.2 27.0 23.5 16.7 9.6 2.0 29.2 20.5 2.8 10.8 42.6 7.2 22.5 15.7 30.3 96.8 14.1 1.7 20.3 0.3 15.4 39.9 6.2 2.0 4.6 5.7 148.2 0.0 6.3 11.5 3.4 12.2 1.5 4.0 31.7 30.7 22.5 5.3 1.7 LPCAT2 "AGPAT11, AYTL1, FLJ20481, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.3;thyroid gland: 86.3" "Cell type enhanced" "Detected in many" "granulocytes: 173.3;Microglial cells: 224.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 23.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.4;eosinophil: 199.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 115.9;HaCaT: 89.2;HL-60: 103.0;HMC-1: 161.7;hTERT-RPE1: 162.9;WM-115: 117.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favorable (3.43e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" 9.8 9.0 5.6 14.4 7.7 88.3 12.2 10.6 5.2 14.0 10.7 9.0 7.4 18.5 36.7 7.8 8.8 10.5 5.7 4.8 8.5 10.9 3.9 10.4 5.0 13.7 8.5 15.8 5.4 13.6 1.0 16.0 15.9 7.0 9.3 7.7 8.4 28.6 2.2 12.0 9.1 15.0 12.7 11.8 9.0 4.1 7.9 3.5 86.3 5.8 4.0 9.5 7.5 22.4 33.5 4.2 3.5 0.3 10.8 4.1 5.6 14.1 13.5 6.8 6.9 7.5 115.9 0.0 46.6 19.9 5.5 89.2 2.2 19.4 10.9 9.1 9.6 34.2 10.2 17.3 4.1 103.0 161.7 2.1 19.2 7.5 6.3 162.9 53.5 1.8 1.5 0.4 11.6 2.1 0.0 41.8 5.1 9.5 0.4 10.4 3.8 5.1 6.8 12.9 2.2 25.3 27.1 10.8 19.9 15.8 4.6 25.8 60.3 0.3 0.1 6.9 9.6 0.6 0.2 0.2 0.5 49.4 117.8 151.4 17.5 199.2 0.0 27.4 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 47.0 0.0 39.1 0.7 0.0 6.5 5.6 7.7 10.6 5.2 4.8 8.5 13.7 8.5 15.9 12.7 7.9 22.4 68.6 6.4 25.7 2.9 1.1 15.4 37.2 68.3 17.1 5.5 8.8 33.9 2.2 4.3 22.3 68.0 10.4 0.7 3.3 7.0 1.9 8.3 1.7 6.4 4.8 41.0 1.2 9.7 8.1 9.7 7.5 20.7 10.2 13.9 173.3 0.4 12.1 2.0 36.5 0.0 11.7 12.2 18.3 71.9 57.7 3.1 16.4 74.4 17.8 224.9 40.6 24.0 0.0 4.5 66.5 32.8 23.0 12.8 1.0 9.0 3.4 3.5 8.1 5.3 0.0 20.0 4.2 49.6 24.0 14.2 15.3 1.9 5.6 7.0 11.6 17.6 LPCAT3 "C3F, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976185-7018477 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.5;Proximal enterocytes: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 156.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.74e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" "unprognostic (3.86e-1)" "unprognostic (2.40e-2)" "unprognostic (6.90e-2)" "unprognostic (1.88e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-1)" "unprognostic (2.58e-2)" "prognostic favorable (4.89e-5)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.23e-1)" 36.6 52.1 8.4 21.6 9.3 28.4 36.3 11.1 9.5 20.3 10.3 51.4 123.0 18.8 21.5 32.0 21.2 18.6 37.4 8.3 9.0 44.4 109.2 46.0 17.0 11.0 9.7 17.7 50.8 19.6 15.2 38.0 9.2 35.9 47.9 4.0 37.3 16.3 45.6 34.0 99.7 21.7 9.2 20.1 58.7 11.2 9.9 21.5 27.7 57.5 21.2 35.3 21.7 9.3 20.2 34.0 15.8 44.3 109.4 51.2 32.9 11.8 49.5 31.7 53.4 78.6 103.9 21.9 6.5 19.1 65.7 50.8 19.2 43.0 24.3 52.7 21.3 44.7 28.2 71.5 23.6 23.3 45.8 81.2 24.7 30.2 15.1 20.1 30.0 33.0 24.4 15.4 20.9 30.0 29.1 28.7 53.1 73.1 20.2 29.9 21.5 22.4 38.7 156.0 13.6 12.5 68.5 107.3 7.9 49.5 10.9 31.4 12.0 19.2 27.8 34.1 8.3 19.1 14.5 30.9 24.0 23.5 17.0 44.4 55.7 91.0 21.5 80.5 25.4 12.3 22.3 24.8 37.2 12.3 20.1 21.3 53.7 32.3 98.7 21.1 29.7 38.3 8.4 9.3 11.1 9.5 8.3 9.0 11.0 9.7 9.2 9.2 9.9 9.3 17.9 70.5 38.5 15.7 13.1 23.6 39.4 35.8 36.5 5.2 19.8 13.8 0.6 12.8 30.3 20.2 0.0 103.5 11.6 47.0 11.7 29.9 2.5 18.8 21.4 13.1 43.2 57.7 20.7 33.0 51.7 14.3 49.5 26.6 14.0 10.6 15.0 62.9 41.6 11.8 16.7 26.8 26.4 21.9 9.6 1.7 18.3 15.2 7.2 6.5 15.8 12.2 15.5 25.6 22.4 18.1 27.1 6.4 17.5 24.7 121.9 37.2 16.4 4.0 19.7 6.0 18.2 24.3 35.3 17.7 22.3 66.4 18.9 17.0 41.2 25.9 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.2;Gastric mucus-secreting cells: 131.5;Urothelial cells: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 108.5;OE19: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 19.7 6.2 18.0 12.2 18.3 6.7 17.8 12.8 38.5 21.6 4.0 44.8 30.9 14.4 9.4 36.1 18.7 17.0 26.0 18.8 21.2 9.3 3.4 10.0 9.7 26.2 12.8 11.8 10.2 7.1 11.8 5.1 26.0 11.1 35.9 4.9 11.8 8.8 8.3 18.6 31.2 16.7 8.5 16.3 39.7 3.3 18.1 8.7 8.4 8.0 11.2 22.2 28.9 21.6 13.7 31.9 15.7 12.6 41.4 41.9 7.5 18.8 31.5 17.6 24.0 11.6 36.0 12.4 38.4 26.3 41.3 108.5 13.8 35.5 7.8 25.2 8.2 12.5 13.6 11.3 8.5 13.5 12.3 31.3 15.8 16.6 21.4 40.6 29.0 22.1 8.3 23.6 33.1 13.3 11.9 26.1 15.7 113.7 26.0 14.7 17.6 25.1 38.7 32.4 12.6 9.5 11.3 14.9 7.3 18.2 11.5 17.9 36.4 32.5 19.6 51.8 18.3 28.5 23.9 4.3 24.3 37.0 7.6 0.1 0.8 3.6 2.7 1.1 6.6 1.6 3.2 4.2 1.3 2.3 1.8 1.7 3.5 1.7 1.4 4.6 5.6 0.8 18.0 18.3 12.8 38.5 18.8 21.2 26.2 12.8 26.0 8.5 18.1 21.6 31.0 25.6 5.9 8.8 13.1 4.8 7.8 35.5 15.4 15.5 5.8 8.3 12.8 25.8 63.1 9.2 4.2 4.9 15.7 85.2 1.9 11.6 0.0 7.1 7.8 31.9 25.3 9.2 57.5 9.8 17.1 9.6 131.5 10.1 12.0 5.5 23.6 0.7 7.9 10.1 53.3 58.0 24.4 8.1 9.7 1.2 15.5 6.3 8.8 9.4 5.7 1.7 9.2 12.5 7.2 43.1 83.4 6.8 29.1 9.7 58.7 2.8 40.7 5.9 13.1 5.1 11.9 2.5 8.1 20.3 6.1 2.5 19.9 8.6 71.8 129.9 LPGAT1 "FAM34A, FAM34A1, KIAA0205, NET8" ENSG00000123684 "Lysophosphatidylglycerol acyltransferase 1" Q92604 1 211743457-211830763 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.1;Oligodendrocytes: 474.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (3.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (9.47e-3)" "unprognostic (1.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.70e-2)" 20.0 19.7 17.0 13.4 29.4 20.0 13.4 13.8 19.5 11.4 21.3 9.3 23.6 9.0 10.1 7.7 8.5 12.1 11.8 14.6 18.0 9.8 36.4 8.8 10.5 18.2 22.4 6.0 13.7 13.9 8.9 9.1 17.8 10.1 10.3 41.1 9.4 12.4 9.9 6.2 35.0 12.2 13.2 16.7 7.4 22.3 21.7 8.2 25.8 14.9 9.8 13.8 7.4 39.2 28.2 30.4 9.8 23.5 17.4 24.2 14.1 19.7 31.2 18.0 16.5 9.1 22.9 11.5 11.3 30.7 20.1 15.0 33.2 17.6 22.6 22.6 11.2 12.0 24.5 20.8 20.9 29.9 19.8 14.3 21.2 16.6 21.6 33.1 21.9 16.2 14.0 0.2 24.1 8.8 11.4 11.1 10.7 12.0 4.9 27.2 38.8 3.5 20.1 23.0 56.6 29.3 32.3 33.9 33.9 15.1 17.3 19.3 21.3 32.7 14.4 30.3 32.5 16.1 21.2 30.2 16.2 25.0 22.8 12.3 2.7 16.1 1.4 2.2 1.1 1.8 0.9 1.0 3.2 1.0 0.2 0.8 12.1 5.3 1.7 2.4 0.2 0.9 17.0 29.4 13.8 19.5 14.6 18.0 18.2 22.4 17.8 13.2 21.7 39.2 50.0 28.9 21.0 28.7 42.2 12.2 77.7 11.5 38.1 206.3 32.2 18.9 40.4 72.9 16.9 12.9 62.6 2.3 73.2 25.3 1.9 71.9 416.1 39.1 39.2 31.6 13.8 15.3 73.5 59.4 4.7 30.9 19.9 28.0 12.7 22.0 25.0 56.2 20.9 35.3 92.3 14.6 26.4 49.7 27.3 60.2 47.2 44.9 30.2 46.9 58.6 34.7 49.4 70.4 474.0 47.8 19.5 55.7 15.0 53.3 126.1 24.2 38.2 127.6 19.7 47.1 33.2 67.2 33.3 30.7 7.5 1.1 32.5 129.4 23.4 63.1 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 207.2;Kupffer cells: 255.8;monocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 86000000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 40.2 66.9 24.6 64.5 25.5 180.4 53.6 29.4 30.6 55.6 33.8 48.2 78.1 51.1 38.4 110.1 61.7 40.3 35.5 25.0 27.8 58.1 43.9 190.8 64.1 26.3 25.4 110.5 54.9 53.3 37.4 27.4 26.0 41.1 49.6 36.9 41.2 40.9 45.0 67.8 60.5 58.3 25.7 57.8 46.6 19.9 28.1 49.2 49.4 45.0 96.4 51.9 52.7 33.0 85.2 90.4 123.5 73.4 104.2 115.1 53.8 33.7 101.8 67.5 78.1 66.6 72.0 190.0 42.0 51.9 52.8 108.3 103.4 140.1 92.3 63.3 97.0 68.5 54.3 81.8 61.8 35.7 39.4 110.1 118.4 91.9 114.5 305.3 134.9 101.1 42.9 32.5 98.7 59.2 96.7 115.0 145.8 100.7 115.5 88.9 90.5 109.7 125.7 107.7 63.9 75.5 64.2 80.4 78.3 95.1 98.7 44.7 49.0 28.3 47.6 40.2 38.2 42.8 79.4 85.4 19.1 66.2 22.3 4.4 662.9 17.7 33.4 699.2 63.4 126.1 46.6 43.4 282.3 157.5 65.0 50.5 46.0 120.4 638.8 70.4 51.2 591.5 24.6 25.5 29.4 30.6 25.0 27.8 26.3 25.4 26.0 25.7 28.1 33.0 32.8 38.5 135.0 15.3 82.8 51.9 64.8 96.6 52.3 21.4 41.8 41.1 25.3 25.8 110.2 38.6 33.3 29.3 47.9 17.6 74.3 42.9 74.3 18.4 20.8 38.2 21.6 50.5 21.3 28.0 28.2 29.7 38.2 27.3 7.6 31.5 57.8 21.7 207.2 11.8 18.5 40.4 40.7 255.8 76.6 16.4 36.7 183.3 21.4 10.3 245.5 35.5 26.8 19.6 17.5 20.8 27.1 41.0 40.1 35.4 73.2 69.3 45.0 55.6 6.6 26.7 35.4 46.9 11.6 108.0 74.9 20.8 39.1 32.9 70.4 49.7 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "granulocytes: 327.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.2;eosinophil: 63.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.1" "Cell line enriched" "Detected in some" 11 "HMC-1: 102.0" "Low region specificity" "Detected in many" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 8.9 6.9 1.1 0.5 0.8 2.3 5.5 1.5 1.3 4.2 0.7 3.3 0.7 5.7 0.0 3.1 11.8 0.3 12.4 1.0 1.4 7.1 1.9 7.7 0.2 2.1 1.5 5.7 2.0 0.2 3.5 0.4 1.4 4.8 0.2 0.0 4.3 0.8 1.0 3.1 3.2 0.4 2.9 6.1 3.0 1.5 2.6 0.0 5.9 0.0 0.1 4.8 4.0 4.7 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.9 8.9 0.2 0.4 0.3 0.6 102.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.2 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.1 20.2 0.5 63.1 0.8 0.6 3.0 0.3 2.1 1.5 8.6 0.2 0.4 1.0 0.3 4.7 0.0 0.4 0.2 0.6 1.1 0.8 1.5 1.3 1.0 1.4 2.1 1.5 1.4 2.9 2.6 4.7 32.3 0.0 3.2 2.9 2.3 9.9 9.6 11.2 14.8 0.4 26.4 38.6 0.0 14.3 6.2 14.7 0.0 10.4 5.0 0.6 1.9 5.9 0.3 4.0 1.5 49.5 3.0 2.1 0.8 2.4 1.9 8.3 3.1 5.6 327.4 0.5 72.1 0.9 41.5 0.0 0.7 1.7 0.0 20.8 46.3 0.9 16.4 53.9 1.8 28.1 2.0 0.1 2.1 1.0 1.5 1.9 0.5 47.4 10.0 3.7 2.2 54.8 5.8 0.5 0.0 0.8 1.6 0.1 0.7 5.2 7.0 3.0 10.0 1.5 3.1 10.0 MBOAT1 "dJ434O11.1, LPEAT1, MGC44669, OACT1" ENSG00000172197 "Membrane bound O-acyltransferase domain containing 1" Q6ZNC8 6 20099684-20212469 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 18.8;Langerhans cells: 25.2;Oligodendrocytes: 41.5;Respiratory ciliated cells: 19.1;Suprabasal keratinocytes: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 42.2;HEL: 40.6;T-47d: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.26e-2)" "unprognostic (4.18e-2)" "unprognostic (2.06e-2)" "unprognostic (5.85e-3)" "unprognostic (3.88e-2)" "unprognostic (5.31e-2)" "unprognostic (2.55e-2)" "unprognostic (6.57e-3)" "unprognostic (1.87e-1)" "unprognostic (1.62e-3)" "prognostic unfavorable (9.15e-4)" "unprognostic (2.90e-2)" "unprognostic (5.59e-2)" "unprognostic (5.17e-2)" "unprognostic (2.56e-1)" "unprognostic (1.70e-1)" "unprognostic (4.24e-2)" 7.3 3.3 1.4 6.0 3.6 11.1 12.5 4.6 2.4 13.3 1.9 19.2 13.8 14.2 5.8 10.5 21.7 8.4 5.9 1.1 2.1 6.1 4.5 7.4 5.4 7.4 3.8 12.5 5.8 5.7 2.4 4.0 6.3 9.3 18.9 1.2 8.1 5.3 1.9 6.8 16.4 8.4 4.6 7.3 15.2 1.4 4.1 2.7 7.6 2.2 5.2 8.6 10.9 9.4 4.5 4.7 8.3 6.6 0.9 2.7 0.6 7.1 2.0 4.4 5.1 2.3 19.0 0.0 14.5 6.8 3.9 42.2 7.6 3.6 6.3 11.3 4.5 40.6 7.9 0.1 5.5 10.6 11.9 1.2 3.6 1.9 8.1 2.3 2.4 7.1 5.4 7.2 1.0 4.7 6.3 10.1 2.1 4.4 2.3 2.0 9.1 25.0 5.9 8.7 0.4 5.3 1.4 8.6 9.0 15.9 31.2 5.3 2.0 6.0 4.2 3.6 3.4 9.7 20.9 0.1 0.6 7.9 7.9 39.9 27.6 66.8 3.9 33.3 20.2 2.6 9.1 7.2 15.1 1.6 2.6 2.6 34.4 4.4 41.1 18.5 13.5 7.9 1.4 3.6 4.6 2.4 1.1 2.1 7.4 3.8 6.3 4.6 4.1 9.4 1.3 3.2 0.5 0.3 1.7 11.0 0.9 3.5 4.6 0.0 2.4 1.3 0.4 0.0 6.6 0.0 0.0 0.1 3.7 3.5 1.9 2.7 0.0 4.7 3.1 2.5 0.0 8.4 1.1 1.2 0.1 6.4 18.8 7.5 0.0 1.9 1.1 0.0 1.5 0.0 0.5 2.0 2.0 1.0 25.2 0.0 0.3 4.4 8.8 6.5 4.5 1.3 0.0 0.0 41.5 1.5 7.7 0.0 1.5 0.8 5.5 0.0 19.1 0.1 0.0 1.0 3.6 0.0 0.1 5.4 15.5 0.3 6.4 10.4 3.0 1.8 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 171.1;Erythroid cells: 162.6;Excitatory neurons: 134.6;Horizontal cells: 141.3;Oligodendrocyte precursor cells: 177.4;Oligodendrocytes: 230.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" 2.2 2.1 16.4 2.4 23.6 26.9 9.0 20.5 18.4 7.7 26.2 7.6 2.4 4.6 2.7 15.8 2.9 3.6 4.6 18.9 21.9 7.0 0.8 6.7 1.9 21.8 22.2 5.8 1.4 29.3 5.4 3.2 22.4 14.4 8.5 15.6 5.7 2.3 1.1 11.6 3.7 3.9 20.6 2.4 6.1 2.1 21.9 2.4 4.5 1.1 4.8 3.8 8.4 29.3 14.0 4.2 12.7 5.4 5.6 12.5 7.3 6.5 2.4 8.5 5.6 1.1 21.9 3.9 7.5 15.9 6.8 10.5 11.4 13.5 12.6 12.3 19.0 16.7 5.9 0.0 6.9 0.0 5.0 9.1 7.8 8.1 5.6 18.5 4.5 5.5 14.4 3.0 7.5 3.6 4.9 0.3 5.0 6.4 15.8 7.4 20.0 0.1 12.6 2.0 7.6 23.0 6.9 41.1 6.6 6.2 7.7 4.8 2.5 14.7 7.7 11.6 19.0 1.1 0.4 4.3 23.3 2.4 5.1 4.7 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.0 0.2 16.4 23.6 20.5 18.4 18.9 21.9 21.8 22.2 22.4 20.6 21.9 29.3 7.7 19.2 12.7 171.1 1.7 3.3 4.6 33.1 0.6 20.6 18.1 12.1 12.2 7.2 54.7 40.5 8.4 3.9 1.1 28.2 5.9 5.6 9.7 3.2 19.4 13.4 37.6 162.6 134.6 1.5 1.4 12.7 21.4 2.9 8.2 14.7 4.6 0.2 1.8 141.3 107.8 59.3 32.6 1.9 17.7 12.7 5.3 5.0 14.2 33.7 29.0 98.7 0.0 177.4 230.5 88.1 42.9 7.5 0.3 19.5 1.6 10.4 45.7 8.8 6.6 10.5 15.2 12.1 24.8 24.4 5.1 1.9 2.0 1.9 12.7 66.4 MBOAT4 "FKSG89, GOAT, OACT4" ENSG00000177669 "Membrane bound O-acyltransferase domain containing 4" Q96T53 8 30131671-30144665 "Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 3.6;stomach 1: 3.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Cholangiocytes: 12.8;Ductal cells: 3.1;Enteroendocrine cells: 3.5;Excitatory neurons: 2.4;Inhibitory neurons: 3.1;Oligodendrocyte precursor cells: 3.0;Oligodendrocytes: 5.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Hep G2: 3.1;OE19: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044509 Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA044509: AB_2678966" "unprognostic (4.35e-3)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (3.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.76e-2)" "unprognostic (1.85e-3)" "unprognostic (4.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (6.30e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-6)" "unprognostic (9.87e-3)" "unprognostic (1.58e-1)" "unprognostic (2.18e-1)" "unprognostic (3.66e-2)" 0.1 0.5 0.1 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 1.7 0.9 0.2 0.1 0.1 0.1 0.4 0.3 0.4 0.1 0.1 0.1 3.6 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.4 3.7 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.1 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.7 0.0 0.4 0.6 0.2 1.0 0.7 1.2 0.8 0.8 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 1.1 0.0 0.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.6 0.0 0.2 0.0 1.0 0.0 0.0 0.0 3.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MBOAT7 "BB1, hMBOA-7, LENG4, LPLAT" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "basophil: 157.3;eosinophil: 265.9;neutrophil: 239.1" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Cell line enhanced" "Detected in many" "HMC-1: 216.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA055967: AB_2682990" "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (5.55e-6)" "prognostic unfavorable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favorable (4.31e-4)" 14.9 108.4 17.6 13.4 14.8 13.1 13.7 0.0 21.4 19.0 0.0 27.8 27.0 19.0 6.6 20.6 20.1 9.2 12.8 17.6 34.4 19.2 16.0 23.6 4.8 24.9 27.8 23.0 21.0 18.9 22.8 6.9 29.2 17.3 5.3 1.0 18.6 20.2 7.9 21.1 25.3 4.4 2.7 26.6 19.9 36.3 28.7 3.2 15.9 1.1 2.3 32.5 18.1 4.8 66.8 43.2 3.8 50.8 21.0 15.4 57.1 90.5 42.6 32.9 49.2 22.1 64.3 11.3 46.5 34.4 10.9 111.9 0.3 26.1 9.0 16.1 54.6 12.8 30.0 12.6 18.9 29.0 216.2 31.0 17.9 17.3 9.8 44.1 46.0 11.0 51.6 42.2 9.2 32.2 10.9 22.7 22.0 21.1 60.1 28.4 7.3 24.9 47.0 71.1 2.3 14.3 57.3 37.0 16.3 4.2 34.5 2.8 73.1 49.4 16.0 12.1 40.8 17.4 31.0 6.4 66.1 25.8 27.9 157.3 22.5 265.9 2.2 11.8 3.3 1.8 3.2 1.7 24.8 1.5 1.1 1.7 239.1 7.8 7.0 7.0 1.9 8.6 17.6 14.8 0.0 21.4 17.6 34.4 24.9 27.8 29.2 2.7 28.7 4.8 11.8 12.8 26.4 11.4 11.3 13.9 66.4 29.2 14.8 15.4 31.1 19.8 8.4 31.5 23.2 44.1 6.2 43.5 15.2 88.8 5.9 52.2 1.1 28.7 22.1 18.5 42.5 13.9 18.7 33.1 52.2 16.3 10.7 26.4 76.8 25.3 15.0 22.7 32.2 30.3 13.6 49.6 16.2 36.8 38.1 4.3 19.3 52.5 8.8 8.4 48.9 24.6 3.1 5.5 9.3 28.6 43.0 15.4 9.3 44.5 101.1 14.5 28.5 8.5 39.5 7.7 19.6 5.1 15.0 17.9 21.6 51.6 23.0 46.3 46.6 47.2 MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.7;fallopian tube: 22.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Early spermatids: 186.0;Endometrial ciliated cells: 50.1;Late spermatids: 33.7;Respiratory ciliated cells: 100.5;Spermatocytes: 114.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 3.6;SCLC-21H: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA073761 Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA073761: AB_2732241" "unprognostic (1.03e-2)" "unprognostic (9.44e-2)" "unprognostic (1.58e-1)" "unprognostic (9.84e-2)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (2.01e-1)" "unprognostic (3.66e-2)" "unprognostic (3.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (7.84e-3)" "unprognostic (3.01e-1)" 0.4 1.5 2.2 0.2 2.5 0.1 1.2 1.9 2.4 1.7 15.7 1.2 0.0 1.7 1.7 0.5 22.5 0.8 1.3 2.4 2.8 3.1 0.3 2.0 0.3 4.2 5.3 1.0 0.9 4.2 9.3 0.0 3.9 0.9 0.5 8.5 1.0 1.3 0.4 0.4 0.3 0.8 3.5 0.2 0.7 24.5 2.8 0.5 4.8 0.5 0.2 0.5 0.4 3.0 0.3 1.2 0.9 2.5 0.1 1.1 0.3 0.0 0.4 0.5 0.3 0.1 0.8 0.5 0.5 0.1 1.1 0.6 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.8 0.5 0.4 1.2 0.7 0.2 0.0 0.1 0.5 0.7 1.1 0.0 0.7 0.3 1.5 0.8 0.3 1.6 0.1 1.4 1.6 0.9 0.0 3.6 0.2 3.5 0.7 1.1 0.5 0.3 0.5 1.1 0.0 0.0 0.6 0.6 0.1 0.3 0.3 1.6 0.2 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 1.9 2.4 2.4 2.8 4.2 5.3 3.9 3.5 2.8 3.0 0.2 6.4 1.5 6.8 0.0 0.8 1.4 3.9 1.8 3.0 2.1 2.4 1.3 2.8 6.4 0.0 0.0 0.1 0.0 0.0 13.7 1.3 186.0 50.1 1.2 0.6 1.2 0.0 8.9 0.0 0.1 1.3 1.5 1.6 0.0 1.1 0.0 0.0 0.1 3.3 6.3 0.0 10.2 0.0 0.2 33.7 1.8 0.5 1.8 1.9 0.0 9.6 0.0 1.0 1.3 0.1 0.0 3.0 0.0 0.4 0.0 6.0 100.5 10.2 0.0 0.5 1.7 114.9 5.1 0.5 0.3 0.0 0.2 1.6 0.1 0.9 MEIKIN ENSG00000239642 "Meiotic kinetochore factor" A0A087WXM9 5 131806990-131945698 "Metabolic proteins, Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.0;testis: 7.5" "Cell type enhanced" "Detected in some" "Astrocytes: 179.6;Excitatory neurons: 46.6;Inhibitory neurons: 54.4;Microglial cells: 27.2;Oligodendrocyte precursor cells: 35.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.21e-1)" "unprognostic (2.30e-1)" "unprognostic (2.64e-2)" "unprognostic (5.27e-2)" "unprognostic (4.31e-1)" "unprognostic (4.64e-6)" "unprognostic (2.38e-1)" "unprognostic (3.81e-1)" 0.1 0.0 1.5 0.1 1.5 0.0 0.0 1.8 3.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.4 0.1 0.1 0.1 0.0 1.5 1.4 0.0 0.0 0.1 0.0 0.3 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 1.3 0.2 0.0 7.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.1 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 1.5 1.8 3.0 1.6 1.4 1.5 1.4 1.4 1.3 1.5 1.7 0.0 0.0 0.0 179.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 54.4 0.0 0.0 0.0 0.0 0.5 0.0 1.9 0.0 27.2 2.2 0.0 0.0 35.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 441.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 276.3;OE19: 558.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 61.8 92.7 43.5 30.4 42.9 42.6 66.6 45.1 60.6 63.6 54.8 112.5 132.5 39.2 82.1 177.6 70.8 87.6 118.3 42.6 45.7 99.2 393.2 49.0 36.0 46.6 44.6 26.3 66.2 102.0 44.6 75.6 46.5 74.9 121.2 7.8 90.6 50.0 104.2 97.1 143.5 57.4 46.6 60.5 72.5 50.6 45.3 35.1 45.8 118.4 64.6 86.7 78.4 48.9 40.8 58.5 28.7 0.3 4.8 15.4 17.7 7.2 66.1 3.2 10.7 62.3 276.3 0.1 158.2 17.5 13.6 74.8 52.7 81.2 4.9 22.3 47.7 174.9 57.3 251.5 13.3 152.7 130.0 53.0 197.2 2.1 12.5 63.9 166.3 0.3 75.9 25.7 23.3 33.9 0.2 24.7 6.5 558.9 59.4 12.7 33.4 54.0 153.0 87.4 71.9 21.6 53.2 83.2 64.8 2.0 52.9 202.2 104.9 5.6 27.3 7.8 6.4 29.7 22.5 9.7 3.8 254.8 12.6 43.8 103.8 30.4 4.1 64.8 2.9 1.3 7.6 3.5 147.0 2.4 2.3 2.6 17.7 26.4 22.2 194.6 37.7 39.4 43.5 42.9 45.1 60.6 42.6 45.7 46.6 44.6 46.5 46.6 45.3 48.9 327.9 25.6 36.6 5.5 7.7 61.1 295.9 316.7 75.7 7.8 99.1 57.3 100.5 205.9 185.5 95.6 25.0 85.3 71.0 168.3 90.1 121.0 6.3 132.5 27.1 238.4 121.8 60.2 19.4 138.6 62.8 31.8 90.2 172.9 43.2 56.9 203.1 419.3 378.1 6.7 24.2 215.1 170.9 107.8 77.8 12.8 44.4 85.3 39.2 49.6 83.6 14.1 27.8 11.6 4.7 121.8 213.1 33.4 7.1 94.6 441.1 277.2 126.6 3.5 13.1 44.6 49.6 4.6 15.1 264.0 124.9 67.2 15.2 43.6 258.2 344.9 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N-alpha-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929225-153935080 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoli "CAB006269: AB_425759, HPA030711: AB_2673579" "unprognostic (7.57e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (1.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.04e-1)" "unprognostic (9.01e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (3.29e-8)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (7.48e-3)" 38.4 39.5 19.6 17.2 20.1 13.2 34.6 20.4 27.2 26.5 19.2 34.1 15.3 32.3 15.1 40.5 24.4 10.3 56.3 20.0 21.8 34.1 35.9 26.0 19.7 20.8 20.3 23.8 45.8 13.7 22.5 12.5 20.8 27.6 10.2 7.3 25.3 12.2 98.4 30.9 24.9 18.1 20.4 28.8 35.9 9.1 21.2 10.2 21.7 24.9 15.3 35.9 26.8 20.4 133.4 136.0 25.8 83.0 36.7 36.9 71.2 46.3 28.6 63.8 57.0 88.5 41.0 102.0 147.6 38.7 79.2 63.0 57.9 56.8 23.9 42.1 255.2 36.8 85.8 91.3 49.1 71.4 76.8 28.8 62.2 57.9 59.1 30.7 72.0 39.2 75.1 41.5 41.6 172.8 115.0 106.4 42.9 124.4 189.0 90.1 65.7 111.5 47.7 59.7 54.0 65.7 18.7 71.0 113.7 23.9 38.4 58.8 41.1 25.6 88.5 89.5 142.0 86.3 107.2 196.0 34.7 91.0 75.5 35.3 53.1 81.3 60.0 65.3 78.1 75.2 63.4 65.6 69.4 77.7 37.4 56.7 49.8 64.7 76.0 75.9 102.9 70.6 19.6 20.1 20.4 27.2 20.0 21.8 20.8 20.3 20.8 20.4 21.2 20.4 126.9 9.6 30.2 27.1 76.0 70.1 66.1 90.6 68.3 29.5 82.6 113.8 45.1 47.1 52.8 38.6 12.5 125.9 77.0 94.5 95.9 121.1 2.9 46.0 60.7 98.7 58.1 78.9 18.6 149.9 179.0 57.3 76.5 43.4 67.9 64.2 77.8 78.7 123.1 37.0 14.6 92.2 54.9 66.5 96.0 12.5 46.6 66.4 119.2 9.4 84.8 37.9 85.5 14.1 19.1 144.6 75.2 46.6 104.3 136.9 91.5 197.0 40.2 30.4 65.7 56.6 98.3 7.6 33.1 120.7 90.5 108.8 74.8 97.7 110.3 85.9 NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N-alpha-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017310-20033655 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA063344: AB_2684991" "unprognostic (2.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (6.18e-2)" "unprognostic (9.30e-2)" "unprognostic (3.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" 50.4 53.3 38.9 34.8 40.6 46.5 65.3 41.6 51.6 40.8 54.0 41.9 27.9 41.7 54.2 113.5 41.6 32.6 61.7 40.2 42.9 85.2 82.5 40.2 37.3 40.9 41.3 33.0 62.7 103.9 26.7 53.0 41.9 43.5 42.8 49.6 47.1 46.9 84.9 38.2 33.9 46.2 42.3 31.8 42.1 66.6 41.5 37.1 59.7 73.6 51.0 51.3 44.1 44.5 212.7 139.9 50.1 69.4 95.0 116.6 67.7 149.2 100.3 132.1 123.8 67.0 137.7 108.4 80.6 113.6 125.5 156.3 85.8 233.2 153.2 51.4 75.7 79.4 49.6 132.6 141.2 102.2 65.9 122.4 182.1 132.8 153.9 93.2 139.7 80.4 126.7 115.7 157.6 177.2 128.6 149.9 37.9 181.5 180.7 69.8 191.9 148.3 190.0 70.4 84.1 62.2 81.9 254.1 170.7 42.5 145.4 171.1 113.7 106.6 75.4 137.8 153.8 130.0 171.9 116.9 66.5 76.2 76.7 39.7 86.2 70.1 55.5 97.5 83.6 63.3 65.9 65.4 92.9 56.6 63.5 75.0 12.5 70.3 81.8 77.7 75.6 100.6 38.9 40.6 41.6 51.6 40.2 42.9 40.9 41.3 41.9 42.3 41.5 44.5 60.5 67.3 42.2 17.0 44.9 108.7 113.6 312.4 45.5 52.9 62.9 75.2 73.1 77.2 147.8 104.8 25.0 111.8 51.4 32.6 230.9 194.0 399.9 99.5 87.6 77.4 41.3 28.8 18.0 169.0 102.2 66.4 31.1 75.8 51.3 46.5 50.3 72.9 255.9 69.0 22.7 43.8 164.8 66.8 56.1 60.5 69.9 68.6 71.2 31.9 100.1 91.5 58.7 16.1 25.2 198.0 37.1 74.9 44.2 184.5 45.7 242.6 199.9 60.7 39.5 75.8 90.8 354.2 58.3 122.5 118.8 85.5 40.8 99.5 54.2 141.7 NAA40 "FLJ13848, NAT11" ENSG00000110583 "N-alpha-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957319 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 102.6;Late spermatids: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037816, HPA056142" Uncertain Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Centriolar satellite, Cytosol" "HPA037816: AB_10672289, HPA056142: " "unprognostic (3.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-1)" "unprognostic (6.88e-3)" "unprognostic (1.50e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (1.43e-7)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (7.01e-3)" "unprognostic (6.29e-3)" "unprognostic (3.42e-2)" "unprognostic (6.43e-3)" "unprognostic (2.49e-1)" "unprognostic (1.55e-1)" "unprognostic (5.25e-2)" 3.3 8.9 5.1 3.9 5.1 2.5 4.4 4.5 5.7 4.0 5.7 5.2 5.7 3.0 3.3 6.7 6.8 3.6 9.5 5.3 4.9 9.1 3.8 3.6 7.5 5.6 5.3 2.7 6.5 15.1 10.4 6.7 5.2 4.2 4.7 7.2 6.6 4.0 4.7 2.7 5.7 3.1 5.0 8.8 4.8 15.3 5.2 10.0 6.1 8.5 7.3 4.2 3.6 5.0 15.5 17.3 21.7 11.8 6.0 5.9 13.8 11.3 12.0 27.3 19.1 14.8 19.3 9.5 13.6 10.2 18.9 13.7 18.3 8.2 20.1 12.5 11.2 13.0 11.1 16.9 7.9 20.9 10.8 6.0 7.4 17.0 4.6 10.6 18.0 16.1 22.4 6.9 12.9 11.8 22.3 16.3 20.2 14.3 11.8 21.9 19.5 12.1 18.5 11.8 28.7 15.1 17.7 15.2 9.2 15.8 25.1 9.2 11.6 15.1 18.3 8.9 9.3 8.3 5.6 16.5 9.2 8.9 11.9 2.3 0.5 2.7 6.9 0.4 2.4 2.7 1.8 3.3 2.7 2.4 1.1 2.6 0.1 5.2 0.2 3.5 0.5 2.3 5.1 5.1 4.5 5.7 5.3 4.9 5.6 5.3 5.2 5.0 5.2 5.0 4.3 3.2 4.8 12.1 8.1 2.8 2.0 4.5 10.8 30.9 11.5 7.0 14.8 5.7 9.4 18.4 33.3 9.6 12.1 13.6 0.0 5.7 46.3 20.0 7.4 7.6 17.5 7.4 14.3 5.4 12.8 4.8 6.1 8.5 1.3 14.3 9.7 5.2 9.5 102.6 15.6 6.1 10.2 10.3 5.3 130.5 4.7 7.3 1.8 15.0 4.4 8.6 17.5 11.6 10.1 5.9 3.5 7.2 12.2 2.1 10.6 4.1 22.5 23.9 0.0 4.3 4.4 27.4 16.5 6.5 2.8 4.1 8.9 10.4 7.3 1.8 NAA50 "FLJ13194, MAK3, NAT13, NAT5, San" ENSG00000121579 "N-alpha-acetyltransferase 50, NatE catalytic subunit" Q9GZZ1 3 113716458-113746300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 320.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074489 Approved Supported Nucleoli NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoli "HPA074489: " "unprognostic (9.74e-2)" "unprognostic (1.49e-1)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.32e-4)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.51e-5)" "unprognostic (1.62e-3)" "unprognostic (6.82e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.97e-3)" "unprognostic (1.09e-1)" "unprognostic (2.25e-2)" "unprognostic (9.59e-2)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" 88.2 64.2 21.8 72.0 24.7 87.3 58.4 25.2 29.4 49.2 27.2 62.5 48.9 50.1 31.4 93.4 38.5 50.6 50.9 23.7 24.4 64.4 90.3 43.5 84.9 23.6 25.0 51.7 58.7 59.8 23.1 45.0 25.3 52.8 54.1 31.5 69.7 42.1 320.7 53.4 47.5 51.2 25.2 52.6 65.6 53.2 26.6 56.8 58.5 154.4 90.7 87.6 46.3 28.2 589.6 250.7 135.2 158.5 179.4 144.6 281.4 308.5 172.4 186.0 212.4 362.3 205.7 403.4 185.8 164.6 146.9 236.5 238.0 211.1 338.6 85.2 121.5 435.7 182.7 220.3 164.4 459.1 135.7 124.0 163.0 208.8 298.3 122.1 168.7 167.3 279.3 157.8 194.3 277.0 306.2 99.3 303.4 228.3 365.3 309.5 207.2 318.9 141.7 439.9 207.4 119.6 223.6 164.1 229.0 116.5 228.1 150.4 156.9 255.1 253.9 109.1 235.7 174.1 314.2 736.0 200.2 253.2 160.6 17.7 40.8 22.5 45.5 40.5 40.6 55.2 33.7 43.1 44.4 37.1 29.4 39.1 51.8 31.8 38.1 25.6 39.9 52.5 21.8 24.7 25.2 29.4 23.7 24.4 23.6 25.0 25.3 25.2 26.6 28.2 33.9 48.1 39.9 24.8 75.7 168.4 86.6 42.6 76.2 24.8 52.3 31.6 47.5 25.8 45.8 36.8 8.4 46.0 78.2 51.3 78.2 52.9 68.0 44.4 53.1 45.7 19.9 79.5 41.5 55.1 94.6 55.2 35.7 94.3 47.5 45.5 29.3 66.1 61.9 40.4 39.0 31.5 42.7 55.3 148.8 50.7 30.7 60.1 62.2 20.6 49.9 29.7 29.9 33.2 28.4 65.2 36.8 31.2 74.9 142.0 31.4 71.0 30.0 18.4 19.7 53.1 64.1 53.5 60.8 99.8 177.9 62.5 74.7 37.7 49.3 193.3 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N-alpha-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443649-3486953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favorable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favorable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 25.5 45.4 31.5 16.9 30.0 20.1 25.1 37.5 35.9 28.4 22.7 40.4 40.5 31.6 18.7 31.0 28.2 20.3 48.9 31.9 27.5 52.4 67.5 32.0 20.2 30.8 30.5 26.8 47.9 49.1 41.6 19.5 29.3 35.2 22.6 16.3 26.0 23.9 42.9 24.2 39.3 19.1 28.8 42.9 58.9 32.7 31.2 19.5 32.0 21.2 16.7 28.4 23.2 30.3 16.8 61.9 40.1 44.1 26.5 19.4 39.1 26.9 25.0 29.3 26.6 43.9 30.5 31.7 30.0 29.6 21.0 37.4 40.1 31.2 29.4 49.7 27.8 35.4 25.7 53.0 32.9 53.1 45.6 24.4 27.9 20.4 38.9 29.2 45.1 29.4 44.8 41.4 19.4 73.6 33.4 36.3 50.1 35.8 18.1 42.3 30.8 47.5 27.7 29.7 21.6 42.5 45.8 48.3 24.6 38.5 40.2 34.7 30.8 36.0 27.7 12.8 26.7 35.2 33.6 30.5 12.1 29.0 29.2 33.3 18.6 53.8 17.7 20.6 19.2 11.6 15.8 17.7 18.1 11.0 12.3 16.4 20.0 18.4 23.6 11.6 20.1 19.5 31.5 30.0 37.5 35.9 31.9 27.5 30.8 30.5 29.3 28.8 31.2 30.3 26.3 9.6 16.0 24.8 17.7 0.1 13.4 0.1 17.6 21.2 24.5 16.4 15.5 38.6 5.6 12.9 6.2 28.3 22.7 66.7 43.0 30.1 55.7 33.3 25.7 21.0 27.0 18.7 22.2 41.7 40.0 18.0 37.2 30.9 30.4 18.4 26.7 53.5 32.1 11.8 26.5 43.1 0.0 34.8 0.3 54.4 11.5 23.6 0.0 25.3 27.0 29.3 26.8 22.1 34.8 37.0 54.3 15.8 15.4 20.2 84.2 49.0 3.7 15.3 26.3 16.8 17.7 19.6 24.5 16.5 0.3 33.0 22.9 21.1 35.3 23.5 NAA80 "FUS2, NAT6" ENSG00000243477 "N-alpha-acetyltransferase 80, NatH catalytic subunit" Q93015 3 50296402-50299416 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 65.5" "Cell type enhanced" "Detected in many" "Adipocytes: 6.5;Exocrine glandular cells: 8.8;monocytes: 9.3;Pancreatic endocrine cells: 6.5;Proximal tubular cells: 7.5;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 56.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 56.3" "Cell line enhanced" "Detected in all" "HMC-1: 60.5" "Low region specificity" "Detected in all" HPA039576 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "HPA039576: AB_10794750" "prognostic favorable (3.62e-4)" "unprognostic (1.02e-2)" "unprognostic (6.04e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-1)" "unprognostic (7.78e-2)" "unprognostic (7.49e-2)" "unprognostic (4.62e-2)" "unprognostic (1.89e-1)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (4.38e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.88e-1)" "unprognostic (1.01e-1)" "unprognostic (9.16e-2)" "unprognostic (2.55e-1)" 13.4 12.2 8.2 7.6 9.2 32.4 13.9 10.9 15.2 16.8 3.1 12.3 6.4 13.3 7.0 15.4 15.4 6.3 17.2 8.8 6.5 19.3 14.6 15.5 10.3 11.6 8.0 17.5 15.1 9.0 14.3 5.8 11.9 19.1 7.7 3.8 13.8 10.6 18.0 22.5 13.4 6.8 5.3 16.5 17.7 65.5 7.3 8.2 14.4 7.2 9.7 13.1 15.9 8.9 8.0 6.2 9.0 9.5 10.7 12.3 6.0 7.4 14.6 11.5 9.9 5.4 15.0 24.6 5.5 12.9 9.4 9.9 5.3 24.2 4.7 15.6 9.0 49.2 37.7 12.3 9.4 8.3 60.5 14.8 16.8 19.3 13.3 17.0 14.1 13.2 4.4 22.7 10.5 8.3 9.9 37.7 5.0 3.6 19.9 6.4 3.2 29.9 19.4 3.9 6.3 8.9 8.4 17.5 3.5 5.5 7.6 23.4 11.7 9.2 9.2 11.4 7.3 15.4 8.9 6.1 15.9 15.5 8.8 13.7 3.1 56.3 7.1 4.2 10.3 10.4 9.7 8.6 5.2 7.5 7.6 6.4 0.9 9.8 2.7 2.6 9.4 5.5 8.2 9.2 10.9 15.2 8.8 6.5 11.6 8.0 11.9 5.3 7.3 8.9 6.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 3.8 4.1 0.0 0.0 0.0 3.7 0.0 5.4 4.5 0.0 3.9 4.8 0.0 3.1 3.4 2.1 0.0 0.0 0.0 8.8 5.1 2.1 0.0 3.2 0.0 3.6 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 6.5 0.0 0.0 2.4 0.0 0.0 7.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.1 2.1 6.4 0.0 0.0 NAT10 "FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43" ENSG00000135372 "N-acetyltransferase 10" Q9H0A0 11 34105617-34147670 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035546, HPA057576, HPA071628" Approved Enhanced Nucleoli,Midbody Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoli Midbody "CAB035546: , HPA057576: AB_2683475, HPA071628: AB_2686426" "unprognostic (3.04e-1)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (1.07e-4)" "prognostic unfavorable (9.61e-8)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.83e-5)" "unprognostic (1.24e-1)" "unprognostic (7.18e-2)" "unprognostic (9.55e-2)" "unprognostic (8.69e-2)" 20.6 24.2 16.0 17.3 15.4 20.4 19.6 14.7 17.4 20.1 14.0 17.0 10.2 20.0 13.7 25.7 19.2 9.4 18.4 15.1 15.4 19.5 22.3 14.9 23.4 14.3 13.6 23.1 25.3 16.8 17.5 15.1 14.7 19.4 15.5 16.3 16.7 12.2 24.8 28.9 17.5 15.5 12.6 22.8 18.7 22.0 15.6 19.4 17.2 12.5 27.5 20.3 20.5 16.9 40.0 55.5 29.3 62.0 34.2 30.2 33.6 38.8 28.5 48.4 38.4 62.6 22.6 127.6 28.3 33.0 41.8 59.5 110.5 59.4 59.5 35.9 70.2 58.0 44.5 58.9 31.0 147.3 40.7 31.1 40.0 31.5 88.3 22.8 37.4 60.6 128.6 43.5 40.8 76.0 120.5 65.7 41.9 69.3 65.7 89.3 98.0 53.7 27.8 68.5 43.1 32.6 52.3 54.9 23.6 28.2 55.0 41.0 30.5 42.8 34.0 63.7 72.8 47.0 61.0 120.3 43.3 60.0 43.4 0.7 8.3 2.8 11.7 13.7 15.5 12.2 12.6 13.4 15.5 10.6 12.7 13.2 0.9 15.0 12.9 11.6 12.0 9.1 16.0 15.4 14.7 17.4 15.1 15.4 14.3 13.6 14.7 12.6 15.6 16.9 8.5 6.4 20.7 10.4 12.7 12.2 11.3 6.9 12.5 12.2 8.8 10.2 12.6 7.2 15.1 14.7 12.5 18.1 8.0 5.8 5.9 9.2 6.1 10.1 18.3 10.9 7.2 21.0 22.8 9.6 13.4 14.5 5.6 12.2 5.1 17.3 5.7 7.5 12.0 11.8 21.7 8.9 4.1 5.5 4.4 3.4 9.3 8.5 1.8 6.5 12.9 5.3 7.2 11.6 16.0 8.7 3.5 13.2 9.8 14.8 3.7 5.8 10.6 11.0 13.1 19.6 8.4 20.5 21.6 13.1 13.8 14.4 11.0 19.7 14.3 7.6 NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Horizontal cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" 5.3 13.1 32.9 4.5 32.2 3.9 7.5 32.2 37.8 23.5 30.2 20.5 2.4 23.8 7.8 5.2 25.2 4.0 11.6 33.8 32.5 25.5 6.5 10.5 3.8 29.8 32.9 20.6 8.4 10.7 47.1 6.9 28.7 14.9 2.1 8.4 5.3 7.8 3.0 5.7 8.5 8.8 27.8 7.1 10.1 11.6 36.2 53.6 20.0 1.2 2.9 11.8 10.8 29.0 8.2 27.6 32.1 59.8 12.9 16.3 19.4 29.6 35.5 32.5 46.3 9.7 26.6 3.1 10.3 19.5 16.4 10.6 20.8 18.8 20.0 32.9 168.2 26.1 41.0 21.9 23.3 19.4 25.8 22.7 6.5 22.7 6.2 65.5 24.3 46.9 32.3 9.1 19.7 10.0 33.1 29.7 44.2 16.4 13.1 32.7 19.9 12.6 78.2 15.3 93.4 64.5 11.9 17.8 28.9 12.2 14.5 20.0 28.5 11.8 31.5 1.7 24.5 18.0 7.4 13.7 26.7 3.3 30.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 32.9 32.2 32.2 37.8 33.8 32.5 29.8 32.9 28.7 27.8 36.2 29.0 4.0 6.4 3.2 9.1 3.8 2.9 6.7 4.4 4.6 62.6 11.7 13.8 4.1 5.7 2.6 29.5 35.5 13.3 3.8 1.2 15.6 14.5 1.5 41.7 31.7 7.2 12.7 10.3 12.9 1.1 8.3 10.4 3.1 9.7 0.0 11.5 3.9 3.6 2.9 148.0 13.1 2.1 4.1 0.8 2.4 3.1 11.8 1.7 5.4 2.8 2.3 39.6 1.0 7.1 2.8 4.3 0.4 10.5 2.7 4.4 0.7 3.7 18.1 39.9 0.0 13.8 12.1 4.2 3.9 0.7 0.6 6.0 2.6 9.7 1.1 1.9 NAT16 "C7orf52, FLJ39237" ENSG00000167011 "N-acetyltransferase 16 (putative)" Q8N8M0 7 101170496-101180293 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.7;pancreas: 2.3;pituitary gland: 3.6;retina: 6.9;thyroid gland: 1.8" "Cell type enriched" "Detected in some" 36 "Horizontal cells: 292.7" "Cancer enhanced" "Detected in some" "glioma: 1.3;melanoma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.4;SH-SY5Y: 3.4;SK-MEL-30: 2.7;U-2 OS: 2.9;U-87 MG: 1.7" HPA021918 Uncertain Approved Nucleoplasm NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA021918: AB_1848922" "unprognostic (4.32e-2)" "unprognostic (1.75e-1)" "unprognostic (2.69e-3)" "unprognostic (4.58e-3)" "unprognostic (2.93e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" "unprognostic (1.40e-2)" "unprognostic (2.25e-3)" "unprognostic (2.35e-2)" "unprognostic (4.23e-2)" "unprognostic (2.62e-2)" "unprognostic (5.53e-5)" "unprognostic (7.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.02e-5)" "unprognostic (1.59e-1)" 0.0 0.1 1.5 0.0 1.4 0.2 0.0 0.7 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.7 0.0 0.1 0.0 0.0 0.8 1.2 0.0 2.3 0.3 3.6 0.0 0.5 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.4 0.1 2.5 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.1 0.0 2.4 0.0 0.2 0.0 3.4 0.0 0.1 2.7 0.2 0.1 0.0 0.0 0.1 2.9 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.5 1.4 0.7 2.7 1.0 2.7 0.8 1.2 0.5 0.2 2.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 292.7 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 5.5 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 732.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 2565.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Hep G2: 10.7" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.1 0.3 1.1 0.1 0.5 0.1 0.2 0.1 0.7 0.2 0.0 1.1 4.6 0.1 0.0 0.0 1.2 0.6 0.1 0.8 0.8 732.4 82.7 0.2 0.0 0.6 0.3 1.3 0.2 0.0 0.6 0.0 0.1 0.2 0.1 1.8 0.1 0.1 0.0 0.0 7.2 0.1 0.4 1.1 0.6 0.5 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.1 0.7 0.8 0.8 0.6 0.3 0.1 0.4 1.0 0.8 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 36.8 0.0 0.0 0.0 0.3 187.9 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.9 51.1 0.0 0.0 0.0 1.1 0.0 1.0 0.4 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 61.3 2565.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.6 0.1 NAT9 DKFZP564C103 ENSG00000109065 "N-acetyltransferase 9 (putative)" Q9BTE0 17 74770529-74776367 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021820, HPA057149" Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA021820: AB_1847958, HPA057149: AB_2683350" "unprognostic (7.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.40e-1)" "unprognostic (2.18e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (1.27e-1)" "unprognostic (5.77e-2)" "unprognostic (1.41e-1)" "prognostic favorable (3.21e-5)" "unprognostic (6.50e-3)" "prognostic unfavorable (6.26e-6)" "prognostic favorable (7.80e-4)" "unprognostic (8.50e-2)" "unprognostic (8.64e-2)" "unprognostic (1.03e-3)" 18.2 57.5 24.0 11.4 24.6 13.5 18.1 25.8 27.6 23.3 25.0 17.3 8.0 18.7 23.2 16.3 21.5 8.9 19.4 23.6 24.2 25.1 29.9 17.6 13.6 25.2 24.9 31.0 25.2 18.0 29.4 14.2 25.2 27.7 9.8 11.5 17.1 12.5 16.4 16.0 15.8 11.1 24.4 20.8 19.3 20.9 24.5 13.7 24.4 11.0 11.3 21.7 18.2 25.6 20.9 30.0 18.7 17.2 29.9 37.4 22.3 39.5 34.2 40.7 35.1 51.3 22.8 57.4 14.7 31.2 26.2 22.8 25.6 42.9 25.9 12.0 37.0 37.0 24.6 46.2 34.9 19.1 22.9 34.2 31.9 40.5 61.2 33.7 44.7 36.2 46.8 17.6 30.2 19.9 38.9 15.6 14.5 40.5 42.8 25.6 55.7 33.4 29.2 33.5 27.0 35.7 16.5 48.1 78.0 25.5 44.4 24.7 26.2 47.0 37.7 20.4 37.5 24.1 9.4 32.0 19.4 12.9 30.5 20.4 16.2 7.4 9.2 24.0 18.9 20.7 16.7 13.8 19.9 30.5 28.5 21.1 4.2 16.7 13.9 15.2 9.8 12.0 24.0 24.6 25.8 27.6 23.6 24.2 25.2 24.9 25.2 24.4 24.5 25.6 15.3 6.4 14.5 15.7 22.6 35.1 41.7 25.9 12.5 39.5 24.7 18.9 5.6 5.7 16.4 18.4 47.9 23.3 20.3 14.5 7.9 14.9 5.5 7.6 13.3 14.3 26.4 10.3 24.4 19.5 19.2 17.3 17.3 13.1 1.3 33.0 9.3 9.9 18.0 45.4 20.2 17.7 20.3 14.1 21.0 4.0 29.5 16.8 10.6 5.6 20.7 11.3 18.6 15.6 16.4 18.3 17.0 17.0 15.8 43.7 11.8 14.5 13.5 46.4 6.6 15.1 16.1 20.5 26.4 9.0 29.7 22.2 14.3 23.7 20.8 39.0 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508962-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 37.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.5;Club cells: 44.2;Pancreatic endocrine cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 176.9;LHCN-M2: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" 5.2 37.3 8.7 3.3 8.3 2.9 4.7 7.0 10.6 9.1 4.5 6.3 2.3 7.1 2.1 10.8 5.8 4.6 11.5 11.2 7.0 3.7 1.5 4.6 3.6 7.1 6.6 4.3 3.5 9.8 4.7 2.4 7.2 4.5 1.6 7.4 4.9 11.6 7.6 5.9 3.7 4.6 6.2 4.5 5.2 5.1 7.7 2.3 6.3 3.5 3.3 6.2 7.1 7.8 13.1 15.6 3.8 26.6 15.9 9.4 1.6 3.7 7.7 5.8 3.9 1.8 19.7 1.1 15.9 8.3 6.5 17.3 5.5 176.9 1.8 8.3 1.8 2.2 9.0 3.8 23.4 2.0 22.5 12.2 20.6 16.8 36.0 13.5 5.3 6.4 1.0 12.1 60.8 3.7 2.0 2.8 4.9 4.0 10.4 4.0 4.6 20.5 9.8 5.1 4.2 6.5 30.8 5.9 5.9 2.5 6.7 1.0 3.3 15.0 7.8 36.4 6.8 10.4 6.3 1.5 43.0 4.9 8.7 16.9 5.5 6.8 10.8 4.9 8.5 3.2 7.1 9.0 6.8 3.5 4.7 7.1 1.1 8.4 4.3 3.6 4.9 4.7 8.7 8.3 7.0 10.6 11.2 7.0 7.1 6.6 7.2 6.2 7.7 7.8 5.4 6.4 2.8 5.2 3.8 4.0 5.3 68.5 8.0 15.4 2.9 4.6 3.4 4.3 44.2 16.5 18.8 0.3 7.3 0.8 1.9 6.9 0.2 13.4 3.5 5.7 6.0 1.3 7.8 9.9 1.3 5.0 3.6 17.8 5.7 3.9 5.0 0.7 3.5 8.4 7.6 2.9 12.2 2.7 4.5 0.1 5.6 2.5 3.6 2.8 3.1 10.1 10.3 6.0 2.8 36.4 1.8 4.1 6.3 2.5 0.2 0.7 8.7 15.5 6.6 4.0 4.8 2.9 4.9 4.2 3.8 8.2 6.9 7.5 1.5 6.6 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 278.5;liver: 594.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 791.5;Proximal enterocytes: 1230.1;Proximal tubular cells: 581.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 5.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 5.9" "Cell line enhanced" "Detected in many" "OE19: 909.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 2400000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favorable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" 44.9 87.7 14.6 11.5 16.3 3.0 37.2 15.4 21.6 35.9 16.7 37.4 232.9 32.4 39.1 112.0 71.5 75.3 29.2 22.6 16.0 234.3 594.1 22.1 7.3 13.0 14.4 25.1 16.7 43.9 23.3 15.3 13.4 60.4 33.9 22.6 47.5 31.1 13.0 31.0 278.5 38.1 11.8 7.9 86.0 8.3 16.4 6.4 27.9 29.0 31.6 88.8 44.4 14.4 49.1 207.1 60.6 0.1 220.1 220.4 45.1 79.4 121.8 74.4 81.2 52.9 67.4 0.1 22.9 78.0 153.9 60.7 47.5 83.4 90.3 0.1 15.4 12.5 129.3 279.0 50.4 7.4 25.6 157.3 127.3 99.8 51.1 88.2 201.0 0.0 8.7 0.1 148.5 16.1 0.4 2.0 22.8 909.3 49.8 0.2 17.1 1.4 82.8 152.8 68.4 3.4 98.9 30.0 31.7 59.6 94.6 34.8 161.8 15.4 29.3 169.7 15.0 0.1 0.5 0.3 72.0 0.1 18.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.3 14.6 16.3 15.4 21.6 22.6 16.0 13.0 14.4 13.4 11.8 16.4 14.4 28.9 19.2 28.3 16.6 4.3 38.6 57.6 135.5 66.6 18.7 43.7 41.4 37.4 271.7 78.4 141.6 25.0 47.0 6.4 34.4 150.6 73.4 4.2 100.3 36.2 26.1 26.5 18.7 38.4 178.3 32.5 48.6 174.3 89.3 1.3 35.0 49.6 791.5 53.4 0.0 31.2 76.1 59.0 26.8 16.7 3.6 33.2 15.9 35.6 12.2 22.6 47.0 0.0 17.1 16.1 139.6 86.3 39.5 0.5 63.8 1230.1 581.3 80.3 46.4 13.1 17.4 61.8 15.2 5.3 242.9 30.5 20.5 5.8 46.8 145.9 156.5 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 201.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 22.9;monocytes: 29.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus" "Secreted - unknown location" NA NA 7800000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: AB_2684537" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" 25.2 31.1 8.0 22.8 8.3 25.2 25.8 8.1 8.5 26.7 16.1 53.6 68.5 25.6 39.0 53.8 40.6 22.3 14.7 8.5 8.7 25.9 32.4 30.5 22.1 9.9 9.1 23.4 34.1 25.4 13.3 27.5 9.1 25.9 57.0 4.2 38.3 27.6 18.8 37.0 58.1 28.1 9.1 33.4 28.5 17.9 10.6 21.7 33.2 12.7 26.5 23.3 28.8 11.8 66.2 71.0 40.8 62.7 65.1 61.3 102.1 49.5 95.6 60.9 67.6 51.8 83.1 14.3 61.8 87.8 38.0 117.4 52.5 97.2 42.4 39.1 67.6 35.5 32.5 48.7 55.1 92.3 121.3 55.9 97.9 54.1 62.0 74.7 110.6 34.8 82.5 21.6 62.1 61.0 12.8 40.2 58.4 105.4 34.4 48.3 57.5 101.6 128.7 61.2 46.9 39.9 122.2 155.9 52.1 78.9 116.6 52.4 79.9 28.9 38.0 28.7 61.3 45.3 39.6 12.9 27.8 77.3 58.1 22.9 14.9 22.1 3.0 25.9 4.1 2.5 3.2 3.4 19.8 4.6 2.8 3.2 11.0 2.9 29.9 7.2 5.4 4.0 8.0 8.3 8.1 8.5 8.5 8.7 9.9 9.1 9.1 9.1 10.6 11.8 26.7 9.6 21.5 8.5 19.7 28.8 40.5 31.2 40.5 15.5 32.8 33.1 12.2 38.6 26.7 25.8 10.4 116.6 21.4 136.6 19.6 71.1 5.4 35.9 17.7 26.1 44.9 19.0 12.7 51.2 91.1 26.1 45.3 21.5 15.2 23.2 27.1 51.4 103.7 11.8 11.1 71.9 14.2 81.0 39.4 4.9 25.4 72.9 24.9 15.0 86.7 12.6 17.5 5.5 8.1 47.8 83.4 23.0 23.6 25.0 201.7 65.8 39.1 8.0 26.3 11.4 28.2 22.7 9.5 53.6 21.6 87.6 17.7 33.2 86.6 34.8 SATL1 ENSG00000184788 "Spermidine/spermine N1-acetyl transferase like 1" Q86VE3 X 85092284-85243911 "Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Alveolar cells type 1: 12.8;Alveolar cells type 2: 12.9;Club cells: 6.8;Distal tubular cells: 3.9;Early spermatids: 5.4;granulocytes: 6.3;Late spermatids: 14.0;Respiratory ciliated cells: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060369 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA060369: AB_2684265" "unprognostic (1.77e-1)" "unprognostic (2.06e-1)" "unprognostic (4.69e-3)" "unprognostic (7.88e-2)" 0.0 0.3 0.3 0.0 0.4 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.4 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 12.8 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 6.8 0.0 0.0 0.0 0.2 0.0 3.9 0.0 5.4 0.3 0.3 1.2 0.0 0.0 0.9 0.0 0.0 1.2 0.0 0.2 6.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 14.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.8 0.0 0.4 0.7 0.0 0.0 0.1 9.5 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.7 0.3 0.0 0.0 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SDR42E2 ENSG00000183921 "Short chain dehydrogenase/reductase family 42E, member 2" A6NKP2 16 22165583-22191754 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 3.2;choroid plexus: 1.8;fallopian tube: 2.1;pituitary gland: 1.2;testis: 2.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 38.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 4.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.9" "Cell line enriched" "Detected in single" 6 "RPMI-8226: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.03e-3)" "unprognostic (2.80e-1)" "unprognostic (2.06e-1)" "unprognostic (1.72e-4)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (8.77e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.32e-3)" "unprognostic (2.01e-1)" "unprognostic (7.09e-2)" "unprognostic (4.76e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (6.61e-2)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.4 1.2 0.4 1.8 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.6 0.2 0.0 0.0 0.4 0.0 1.5 3.2 0.1 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.2 0.2 0.3 0.5 0.3 0.3 0.1 0.8 0.5 0.3 4.9 0.4 0.1 0.3 0.3 0.2 0.6 0.7 0.4 1.2 0.6 0.2 1.5 3.2 1.0 1.2 0.4 0.8 8.9 0.0 2.4 2.6 8.7 0.8 0.7 0.9 0.6 7.7 5.2 11.6 1.9 10.0 0.4 0.0 0.0 0.9 7.4 15.6 0.0 0.9 1.8 3.9 8.4 2.6 2.4 5.7 2.0 0.5 0.3 2.6 12.8 3.2 2.5 1.7 5.0 3.4 2.3 5.0 0.7 15.1 4.1 13.1 3.8 1.4 5.9 5.1 1.8 0.0 6.4 14.7 10.3 0.5 0.4 0.3 3.2 1.5 5.9 1.1 38.2 0.6 3.5 3.7 0.0 0.9 3.0 0.6 0.6 1.4 1.7 1.4 11.1 2.6 8.8 0.3 SDR9C7 "RDHS, SDR-O" ENSG00000170426 "Short chain dehydrogenase/reductase family 9C member 7" Q8NEX9 12 56923133-56934408 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.5;skin 1: 58.5;vagina: 21.3" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Suprabasal keratinocytes: 4.0" "Group enriched" "Detected in some" 6 "cervical cancer: 3.0;head and neck cancer: 11.0;melanoma: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (6.75e-2)" "unprognostic (1.42e-1)" "unprognostic (7.90e-5)" "unprognostic (7.93e-2)" "unprognostic (4.20e-3)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (9.31e-2)" "unprognostic (3.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.27e-1)" "unprognostic (1.74e-3)" 0.1 0.0 0.1 0.0 0.1 0.0 2.6 0.2 0.3 11.3 0.0 0.3 0.0 0.4 0.0 14.5 0.2 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.1 0.0 0.8 58.5 0.1 0.0 0.0 0.2 0.1 0.8 0.0 0.5 0.0 0.0 7.5 0.2 21.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.0 0.0 0.0 0.0 0.0 0.0 SH3GLB1 "Bif-1, CGI-61, KIAA0491, PPP1R70" ENSG00000097033 "SH3 domain containing GRB2 like, endophilin B1" Q9Y371 1 86704570-86748184 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 634.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 301.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004650, HPA015608, HPA019900" Enhanced Supported Cytosol NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "CAB004650: AB_425966, HPA015608: AB_1845355, HPA019900: AB_1845356" "unprognostic (1.72e-2)" "unprognostic (1.76e-1)" "unprognostic (5.52e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.90e-5)" "unprognostic (8.34e-2)" "unprognostic (1.75e-1)" "unprognostic (4.29e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (1.56e-1)" "unprognostic (4.04e-3)" "unprognostic (7.70e-2)" "unprognostic (2.65e-1)" "unprognostic (1.88e-2)" "unprognostic (1.69e-1)" 106.5 38.1 20.5 55.3 22.5 66.2 56.1 21.0 25.4 39.2 15.7 53.7 48.4 35.9 31.0 79.4 27.9 47.0 72.8 19.2 23.7 40.4 45.0 49.0 40.9 25.3 19.7 24.2 64.0 41.3 30.3 57.5 24.4 34.3 57.9 39.0 56.4 36.1 172.0 35.8 47.0 50.3 23.4 46.5 36.3 109.5 21.0 34.1 38.6 98.4 51.9 63.8 41.8 27.4 78.1 28.1 44.2 40.4 180.1 155.1 72.2 115.1 114.5 106.8 112.3 81.4 63.3 39.7 72.0 143.5 132.9 44.5 39.4 75.0 101.2 86.1 28.1 94.7 39.2 87.1 108.7 51.5 92.4 111.8 85.5 118.3 128.7 114.5 171.4 41.7 36.0 108.5 145.1 23.1 46.7 32.7 43.0 56.8 47.6 53.1 184.6 29.7 92.3 132.2 47.9 34.7 64.8 82.4 140.8 65.2 32.7 51.8 151.4 102.2 61.9 129.3 96.5 56.8 56.3 58.6 50.8 52.1 63.5 153.0 59.0 66.5 43.0 64.5 42.4 36.8 40.2 43.8 45.5 35.3 19.1 34.3 301.4 62.4 77.0 43.8 65.4 49.5 20.5 22.5 21.0 25.4 19.2 23.7 25.3 19.7 24.4 23.4 21.0 27.4 192.0 83.3 65.6 39.2 75.0 89.6 119.5 124.1 44.3 31.2 96.9 69.1 157.0 60.1 104.0 55.2 52.1 84.3 145.7 182.0 86.1 145.2 634.6 86.3 104.5 135.4 86.6 64.4 49.9 169.8 203.4 99.7 45.9 110.0 113.5 61.0 157.1 79.4 143.7 16.8 50.5 130.3 128.1 149.2 99.4 236.9 70.2 116.0 81.8 40.3 163.7 71.9 124.6 46.8 65.2 201.7 173.4 85.0 123.9 103.4 108.8 134.0 90.2 55.4 78.9 146.7 111.7 403.5 86.3 100.6 118.1 101.9 90.4 57.1 87.4 199.8 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 TECRL "DKFZp313B2333, DKFZp313D0829, GPSN2L, SRD5A2L2, TERL" ENSG00000205678 "Trans-2,3-enoyl-CoA reductase like" Q5HYJ1 4 64275257-64409468 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "heart muscle: 554.3" "Cell type enriched" "Detected in some" 35 "Cardiomyocytes: 1775.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" 0.0 0.3 0.1 0.1 0.3 1.0 0.6 0.8 0.3 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.1 554.3 0.1 0.5 0.0 0.0 0.2 0.4 0.3 0.1 0.1 0.5 0.1 0.0 0.1 0.4 1.7 0.0 0.5 0.3 0.0 56.2 1.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.6 1.9 0.0 0.3 0.0 0.9 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.3 0.1 0.5 0.3 0.1 0.4 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1775.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.2 0.0 0.0 50.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099430-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Astrocytes: 927.8;Excitatory neurons: 270.5;Inhibitory neurons: 540.9;Microglial cells: 471.2;Oligodendrocyte precursor cells: 914.9;Oligodendrocytes: 793.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA050992: AB_2681299" "prognostic unfavorable (9.07e-5)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-2)" "unprognostic (2.32e-1)" "unprognostic (1.81e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (4.33e-2)" "unprognostic (3.50e-2)" "prognostic favorable (4.49e-5)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.77e-1)" 8.6 6.3 18.6 4.0 23.9 4.2 7.4 24.0 20.3 8.6 21.2 5.2 5.3 8.2 10.1 7.7 9.0 7.4 5.2 18.8 22.5 12.7 12.0 5.3 4.6 24.0 22.4 7.6 8.3 12.1 9.8 5.3 25.3 7.7 3.2 6.9 8.5 6.4 3.3 7.1 4.5 5.1 22.0 4.7 6.0 9.3 21.0 9.0 21.8 2.1 6.0 6.7 7.1 30.0 11.1 9.5 9.2 7.7 11.0 5.3 11.1 1.6 3.2 3.7 3.2 7.0 9.6 19.5 8.6 1.5 5.2 10.0 5.1 1.3 2.6 11.0 26.8 6.0 1.9 15.7 7.5 16.7 3.4 5.9 3.8 2.3 2.4 0.9 4.4 25.9 9.2 4.2 2.6 85.7 27.7 21.9 8.6 5.9 5.7 32.2 3.9 19.1 5.3 3.9 17.6 10.0 7.1 11.9 4.0 9.3 12.8 12.0 1.6 2.7 10.4 2.2 6.4 0.0 18.3 41.2 10.4 8.4 4.6 7.0 9.1 2.1 11.4 7.9 13.4 9.3 8.2 9.1 7.7 6.6 8.4 8.3 0.7 9.1 5.8 14.5 13.5 6.0 18.6 23.9 24.0 20.3 18.8 22.5 24.0 22.4 25.3 22.0 21.0 30.0 12.0 6.4 6.9 927.8 9.0 9.2 21.2 8.0 19.4 7.4 12.1 16.1 8.8 17.2 13.3 14.7 4.2 25.7 10.9 4.5 33.2 12.4 43.1 18.2 13.9 9.5 9.6 13.3 270.5 10.3 11.9 12.0 9.2 7.6 12.7 18.7 13.2 18.9 9.2 5.0 540.9 5.1 0.0 5.6 5.7 38.2 14.0 7.7 5.4 471.2 5.9 46.3 9.2 914.9 793.5 4.5 5.9 17.7 18.4 11.5 8.7 28.3 18.7 12.2 6.6 10.3 11.8 19.7 17.9 13.3 6.8 17.4 9.9 12.1 6.8 13.0 YKT6 ENSG00000106636 "YKT6 v-SNARE homolog" O15498 7 44200959-44214294 "Metabolic proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030817, HPA030818" Approved Approved Mitochondria,Cytosol No No 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol Mitochondria "HPA030817: AB_10599828, HPA030818: AB_10602102" "unprognostic (1.25e-1)" "unprognostic (7.35e-3)" "unprognostic (1.30e-3)" "unprognostic (7.80e-3)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.77e-3)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (8.65e-2)" "unprognostic (1.63e-1)" "unprognostic (2.01e-2)" "unprognostic (1.34e-2)" "unprognostic (7.66e-3)" 31.6 33.4 52.4 31.7 51.8 36.9 26.4 50.8 52.2 23.5 46.3 34.9 30.5 30.3 38.7 50.1 22.8 19.9 37.8 53.9 57.8 33.7 20.2 27.7 27.6 56.1 62.8 19.5 52.6 34.3 31.7 27.7 60.2 27.2 34.5 16.0 37.6 27.1 49.6 34.3 29.7 35.0 57.2 30.2 40.4 28.4 58.7 38.4 28.8 36.5 34.9 31.2 24.7 56.5 81.9 86.1 71.3 94.8 85.3 72.6 63.1 161.5 130.3 104.5 103.6 93.7 75.9 88.0 71.4 157.7 184.5 94.5 83.1 111.0 140.8 89.4 65.3 53.7 63.1 58.7 105.1 103.4 80.8 66.7 97.6 114.7 123.4 77.5 111.5 75.9 126.2 64.8 125.2 79.4 87.3 106.8 178.8 111.5 120.2 81.9 76.0 68.4 72.2 69.2 94.2 151.6 83.0 126.4 97.8 115.8 100.0 100.4 138.0 112.5 123.9 104.2 199.1 134.5 187.8 130.3 146.2 87.5 219.4 5.6 10.8 18.2 5.3 11.5 7.9 7.1 7.0 9.0 10.0 10.1 5.4 5.4 8.9 5.1 10.6 7.9 7.5 5.5 52.4 51.8 50.8 52.2 53.9 57.8 56.1 62.8 60.2 57.2 58.7 56.5 12.4 12.8 9.4 9.1 16.2 26.0 18.1 14.1 10.2 8.4 21.6 15.4 19.7 7.2 13.7 20.2 10.4 25.3 13.9 45.4 25.4 47.1 25.4 9.4 15.8 19.3 13.8 9.5 7.0 83.0 63.5 18.7 18.8 17.7 1.3 15.1 14.6 15.7 41.2 13.5 6.5 26.6 16.2 19.4 19.3 8.3 9.9 19.5 26.6 1.0 40.2 11.0 23.7 8.0 8.3 79.0 23.3 13.5 38.8 35.8 33.1 23.1 8.7 7.9 0.0 13.1 23.8 18.9 23.0 22.9 25.9 49.3 15.2 11.8 24.0 44.4 ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 84.6;Late spermatids: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 11.4;ASC TERT1: 11.3;U-138 MG: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA042531: AB_2678041, HPA048659: AB_2680483" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favorable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favorable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favorable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" 17.7 10.9 3.7 1.8 3.5 0.2 17.9 3.2 5.6 27.1 7.4 14.5 2.3 21.7 3.9 6.8 22.4 6.3 10.8 3.4 4.2 19.3 4.4 12.4 1.4 4.9 6.7 23.6 17.7 7.8 20.4 3.1 4.1 19.5 1.7 0.8 17.0 6.7 10.7 19.1 7.4 3.9 4.7 14.9 10.6 20.3 4.4 0.6 29.4 3.0 0.8 12.8 16.3 2.8 5.2 6.0 1.4 7.3 11.4 11.3 0.0 3.2 9.0 2.6 2.8 0.0 2.6 0.0 1.3 4.2 2.5 3.3 0.4 0.6 0.5 1.6 4.6 0.5 0.1 0.4 5.2 0.2 4.0 6.0 5.3 2.7 0.6 6.0 3.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 2.9 1.8 0.1 0.0 0.0 0.0 3.5 2.9 2.1 7.4 0.5 0.1 6.5 0.4 1.9 1.1 5.8 11.7 2.0 5.6 3.3 1.4 0.3 0.0 7.2 0.1 4.7 0.0 1.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 3.7 3.5 3.2 5.6 3.4 4.2 4.9 6.7 4.1 4.7 4.4 2.8 7.0 0.0 0.0 10.4 0.9 7.1 6.7 1.3 10.8 2.2 7.5 7.0 1.1 10.0 1.4 7.3 4.2 2.0 0.3 5.2 9.8 3.4 29.3 84.6 10.9 5.2 9.0 0.4 5.7 4.0 0.2 13.6 8.6 7.3 0.0 8.5 6.1 2.0 2.0 3.3 5.0 12.9 2.0 16.4 6.8 53.0 14.6 9.3 5.4 2.8 8.2 7.9 1.0 4.0 2.5 2.2 4.9 10.9 0.7 7.2 2.0 6.6 5.5 0.5 0.0 5.1 9.4 12.4 8.6 6.2 7.1 5.7 0.7 10.4 6.8 4.8 ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795606-850986 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Early spermatids: 17.0;Endometrial ciliated cells: 26.2;Excitatory neurons: 21.4;Inhibitory neurons: 16.4;Oligodendrocytes: 18.3;Respiratory ciliated cells: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 11.5" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 43: Testis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" 1.9 0.9 8.0 0.4 9.9 0.5 2.1 8.3 13.0 2.7 8.0 3.5 6.1 1.1 1.8 3.9 6.5 0.9 9.0 7.4 5.1 4.1 5.2 4.7 0.5 7.9 9.9 1.7 2.8 0.6 12.0 0.8 9.0 2.8 0.8 4.3 2.7 0.9 2.0 3.1 2.9 0.5 2.3 3.3 4.4 10.4 7.1 0.7 2.4 2.2 0.7 2.4 2.2 15.0 0.4 7.4 4.1 0.9 1.3 0.3 5.4 0.3 0.1 0.2 0.1 1.0 0.3 3.1 0.8 0.0 0.9 7.1 2.6 0.0 0.0 9.6 4.9 0.3 3.0 3.9 0.4 4.5 0.3 0.4 0.3 0.9 1.0 0.3 0.0 1.2 0.7 1.7 0.2 3.5 0.4 2.5 7.3 0.0 2.8 4.6 2.7 4.3 0.2 1.5 4.2 0.8 0.2 0.1 3.5 8.0 11.5 0.8 0.4 0.2 6.9 3.9 0.1 5.6 8.3 0.9 0.3 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 9.9 8.3 13.0 7.4 5.1 7.9 9.9 9.0 2.3 7.1 15.0 0.7 19.2 13.1 8.5 0.0 1.9 0.4 0.6 0.0 3.4 1.6 2.0 7.7 1.5 13.4 0.0 0.0 0.2 0.3 1.2 0.0 0.5 17.0 26.2 3.8 1.5 1.8 0.4 21.4 0.0 0.1 3.6 4.1 4.2 3.8 0.1 1.1 2.7 0.4 6.7 16.4 3.9 0.0 0.0 0.3 9.1 0.6 0.9 0.0 0.0 0.1 0.3 0.0 7.5 18.3 0.2 1.7 0.0 1.4 0.3 6.0 1.3 25.8 2.2 6.6 0.9 1.0 9.5 3.7 0.7 1.6 0.3 1.1 0.1 1.6 0.4 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 29.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.0;Excitatory neurons: 47.2;Inhibitory neurons: 38.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 70.1;Respiratory ciliated cells: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.1;SCLC-21H: 2.4;THP-1: 3.4" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.7 1.2 15.1 0.2 19.6 0.0 0.8 5.9 19.9 0.5 0.0 2.0 2.7 0.4 0.1 1.5 2.0 0.3 4.5 14.6 9.0 0.7 1.2 2.4 0.0 14.2 8.6 0.6 1.8 0.4 4.5 0.2 14.9 0.5 2.3 4.3 1.7 0.5 3.6 2.2 2.4 0.4 3.3 1.2 2.3 0.7 15.5 0.0 1.1 1.6 0.3 1.0 0.6 29.5 0.0 0.8 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 2.1 0.1 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.4 0.4 0.0 0.0 0.7 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 19.6 5.9 19.9 14.6 9.0 14.2 8.6 14.9 3.3 15.5 29.5 0.2 19.2 23.0 17.0 0.0 2.7 1.0 0.1 2.2 7.0 1.1 0.9 8.9 1.5 5.7 3.7 0.0 0.0 0.4 2.0 0.0 0.8 2.5 11.9 0.7 2.8 3.0 0.0 47.2 0.8 0.1 4.7 4.1 3.6 1.3 0.0 0.7 2.3 1.7 10.1 38.3 6.7 0.0 0.6 1.1 0.4 0.9 0.8 0.0 1.9 0.0 0.6 0.0 26.7 70.1 0.1 1.4 0.0 1.7 0.3 7.7 0.5 21.8 0.3 6.6 1.4 2.4 5.0 2.5 2.3 3.1 0.0 1.5 0.5 2.4 2.6 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 18.8 23.9 7.8 15.5 7.7 41.3 19.3 7.5 9.9 16.8 8.4 40.5 26.3 12.9 7.1 67.8 12.0 14.1 13.7 7.4 8.8 30.6 52.3 23.3 20.0 9.6 7.8 7.4 67.1 9.8 11.3 16.3 8.4 26.6 13.7 0.5 43.2 12.5 15.6 42.4 36.8 6.3 8.4 31.7 49.2 24.7 10.5 12.4 16.2 4.1 13.7 18.7 30.5 9.7 53.5 127.6 6.0 31.3 17.6 12.1 59.4 32.8 28.8 34.5 22.9 109.6 61.5 37.3 29.6 25.5 62.9 139.8 13.0 65.0 3.8 65.0 31.7 20.1 92.7 49.1 34.7 33.1 87.1 19.9 44.7 29.6 11.0 17.7 25.6 65.6 18.8 93.6 7.1 187.3 45.9 66.2 26.8 118.8 107.6 21.0 21.0 108.4 28.7 43.4 42.1 30.4 46.2 64.1 18.3 9.6 98.9 35.6 27.5 0.1 36.9 25.9 45.8 58.1 106.8 17.3 61.3 38.4 41.4 231.1 122.3 385.6 105.1 123.9 91.2 94.6 95.9 101.5 100.1 111.0 99.2 91.4 269.5 90.5 150.0 244.7 130.9 101.0 7.8 7.7 7.5 9.9 7.4 8.8 9.6 7.8 8.4 8.4 10.5 9.7 10.0 16.0 12.0 1.3 31.8 16.2 43.3 94.0 10.8 1.2 55.5 30.4 14.8 77.2 59.0 46.0 0.0 183.9 39.1 171.0 13.7 106.8 73.2 20.7 11.5 21.1 51.2 51.1 0.6 200.0 224.0 14.2 38.7 52.5 18.4 13.7 35.7 55.3 137.0 0.0 0.5 108.5 67.1 62.2 20.9 30.0 9.6 46.5 42.7 6.5 115.3 18.4 81.4 0.5 2.0 133.8 167.7 7.2 43.3 56.5 186.0 48.5 20.1 2.0 6.6 5.4 16.3 36.0 18.6 55.2 28.1 134.1 34.1 22.0 110.0 77.5 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.7;Horizontal cells: 122.8;Inhibitory neurons: 108.1;Oligodendrocyte precursor cells: 315.2;Oligodendrocytes: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 4 "HDLM-2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 2.9 1.6 7.3 1.8 7.6 2.5 1.6 9.7 6.8 5.3 1.1 2.4 2.8 12.4 0.4 1.7 2.0 2.3 5.2 7.5 5.1 4.6 4.4 3.0 2.4 12.5 9.1 1.4 2.5 5.6 1.6 2.2 10.9 3.5 1.7 1.3 2.1 1.4 2.3 1.4 4.1 6.1 13.5 3.1 3.8 3.3 10.8 0.9 1.7 3.9 2.4 2.4 1.9 22.7 2.6 2.7 0.8 3.8 2.0 1.5 8.7 4.1 3.7 2.8 2.5 3.3 1.9 6.4 1.4 3.3 5.4 1.3 2.2 2.2 2.5 50.9 3.2 12.7 1.0 1.5 2.7 1.7 2.8 1.1 2.3 2.9 1.2 2.4 4.3 2.8 10.4 4.7 1.6 1.7 1.1 4.2 1.6 5.1 3.2 0.2 0.4 3.9 5.8 1.1 6.3 1.9 4.8 3.1 3.5 1.6 0.4 2.0 6.0 4.2 3.1 8.3 5.2 1.1 1.3 0.9 1.5 4.5 4.7 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 7.3 7.6 9.7 6.8 7.5 5.1 12.5 9.1 10.9 13.5 10.8 22.7 23.4 3.2 0.0 45.4 9.8 12.9 2.1 3.0 4.0 25.3 5.8 8.0 18.3 12.8 1.4 7.3 6.2 12.5 11.2 7.4 11.7 7.5 10.7 5.0 16.6 15.1 2.4 4.2 161.7 3.1 2.2 11.4 6.1 9.4 0.0 7.7 22.5 23.1 11.4 122.8 108.1 9.8 6.1 15.5 6.7 5.9 8.1 8.8 10.6 65.6 3.8 5.4 7.2 315.2 221.0 2.7 8.5 10.1 4.5 14.2 6.0 3.8 0.4 6.0 0.0 6.2 8.4 7.2 10.0 1.5 8.4 21.1 6.6 4.6 11.5 2.7 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.2;Inhibitory neurons: 17.7;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 3.2;K-562: 2.1;LHCN-M2: 2.2;MOLT-4: 2.4;NTERA-2: 2.0;RH-30: 3.1;RPTEC TERT1: 1.7;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA003618: AB_2217686, HPA064901: " "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 0.8 1.5 1.7 0.3 1.7 0.1 1.6 1.8 1.5 1.6 1.3 1.0 0.2 1.9 1.0 0.8 1.2 0.8 1.7 1.5 2.5 1.5 0.2 1.2 0.3 2.2 2.2 2.5 1.1 1.1 1.1 0.0 2.0 1.1 0.5 1.9 4.5 1.1 0.3 0.7 0.3 1.5 1.8 0.8 0.4 0.6 3.0 0.8 2.0 0.5 0.2 0.7 0.8 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.1 0.0 2.2 0.0 2.4 0.0 2.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.8 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.5 0.0 0.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.8 1.5 1.5 2.5 2.2 2.2 2.0 1.8 3.0 2.0 2.9 6.4 3.1 8.5 0.1 4.0 1.6 0.0 3.4 4.2 2.0 1.5 9.5 1.5 1.3 5.5 4.2 0.0 0.3 0.0 0.0 0.7 0.0 0.2 2.9 3.5 1.8 0.4 18.2 0.7 0.0 3.5 0.0 0.3 1.3 2.5 2.2 0.1 0.1 0.0 17.7 0.0 0.0 0.0 4.4 0.2 0.9 0.1 0.0 5.6 0.0 2.2 1.0 17.1 9.1 0.2 0.0 3.8 0.0 0.7 0.0 1.0 0.0 2.3 6.6 5.4 2.5 0.2 0.7 2.2 3.7 0.0 0.5 2.3 0.0 0.6 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 15.6 14.9 17.8 10.2 18.5 6.8 16.3 20.3 21.9 15.0 16.4 17.1 14.3 16.4 18.5 19.9 12.2 9.9 22.1 18.1 16.5 25.1 30.3 20.8 11.3 17.2 17.8 15.9 22.8 25.5 16.7 21.6 16.4 18.3 17.3 17.4 24.2 12.1 25.8 13.1 14.7 16.6 16.1 14.5 24.1 17.3 18.8 12.6 16.0 27.9 15.1 17.1 15.3 16.7 50.7 57.4 37.9 47.1 58.7 40.4 38.7 54.6 72.1 61.2 58.4 45.7 43.6 44.4 60.1 79.8 53.4 58.0 48.2 76.7 54.2 43.7 56.0 28.5 39.8 44.3 47.4 34.0 39.7 45.7 49.8 71.6 51.3 66.3 63.9 40.4 23.1 32.8 79.0 48.4 51.8 46.0 29.9 45.8 49.5 34.0 38.6 40.9 51.9 23.2 18.4 25.9 33.2 33.7 30.6 37.7 44.6 32.9 39.6 38.2 35.0 25.0 64.7 29.2 53.0 26.9 44.1 51.7 20.7 0.3 11.1 11.1 7.2 11.9 8.1 9.0 12.5 11.5 15.7 10.6 10.0 10.1 0.5 14.5 11.8 12.0 11.1 6.8 17.8 18.5 20.3 21.9 18.1 16.5 17.2 17.8 16.4 16.1 18.8 16.7 6.2 19.2 23.1 3.9 9.0 5.2 18.9 31.8 14.8 15.8 13.6 9.3 10.1 14.3 27.6 12.9 4.2 39.8 10.3 11.5 25.4 35.5 24.8 7.0 13.3 11.3 7.2 11.6 8.2 32.3 67.2 13.7 10.2 10.9 7.0 13.3 7.5 19.5 24.6 13.5 9.2 18.9 28.5 7.3 5.9 7.6 8.7 9.3 3.6 9.4 18.4 14.9 15.5 11.1 8.4 31.5 12.1 3.8 17.1 20.0 18.9 22.2 8.3 13.0 6.6 5.2 12.2 20.1 12.9 13.8 4.3 37.9 7.2 10.9 20.9 19.3 ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.2;Inhibitory neurons: 95.1;Oligodendrocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016807, HPA058674" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "HPA016807: AB_1858999, HPA058674: AB_2732626" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavorable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" 15.6 14.1 18.6 12.1 20.4 23.7 16.1 23.1 25.9 15.8 11.8 13.7 7.5 21.7 12.3 8.0 12.8 10.5 12.5 19.8 18.9 11.0 9.8 10.6 14.8 18.2 18.6 20.1 10.2 12.7 11.0 16.4 18.9 14.1 10.1 31.0 8.1 12.8 11.8 10.2 10.3 14.6 19.2 14.4 8.5 12.8 19.4 14.9 11.8 14.2 11.4 11.7 11.7 27.8 8.2 9.5 30.1 15.4 17.6 18.5 14.6 16.2 13.4 10.5 9.2 7.8 5.8 11.2 9.5 15.9 10.5 7.5 12.1 10.1 16.2 9.5 12.6 16.4 13.1 12.0 11.9 16.5 13.9 17.6 10.3 10.0 14.7 35.2 12.2 15.2 18.0 5.2 13.8 7.6 12.0 21.9 22.1 3.6 11.3 16.1 10.7 12.3 12.0 12.3 11.7 20.1 17.8 6.4 10.7 25.7 14.4 16.3 16.9 14.3 11.0 8.8 9.3 8.1 8.5 11.9 5.4 7.6 15.0 6.2 2.3 5.7 3.6 2.4 2.9 2.5 2.9 2.6 2.8 3.9 3.0 2.5 5.9 2.0 2.5 17.1 1.3 1.5 18.6 20.4 23.1 25.9 19.8 18.9 18.2 18.6 18.9 19.2 19.4 27.8 33.4 32.1 18.3 75.7 20.1 7.1 10.4 9.8 12.5 54.6 9.9 10.7 21.3 12.8 15.5 12.9 39.6 20.3 74.1 5.0 0.0 8.0 11.3 11.8 23.8 24.8 19.2 12.0 102.2 4.7 10.2 21.2 7.1 10.1 41.2 20.7 20.3 10.6 8.8 28.6 95.1 7.5 8.2 12.3 19.4 13.7 20.2 14.9 5.4 54.4 14.9 26.1 18.6 88.4 115.8 6.8 4.5 21.1 13.5 10.2 8.4 5.5 18.0 38.1 0.0 32.3 22.0 17.7 22.6 9.5 5.5 5.6 18.1 19.6 6.2 5.5 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Cell line enhanced" "Detected in all" "HDLM-2: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 23.4 8.1 26.0 27.4 24.6 113.9 17.0 25.7 29.0 12.9 16.9 14.6 12.9 13.6 4.6 24.3 11.3 14.8 15.0 25.4 30.0 8.8 18.6 16.2 22.1 29.1 28.7 9.6 10.5 8.6 11.7 23.3 33.5 11.4 15.0 19.3 16.9 9.1 10.8 18.5 13.9 18.4 22.2 31.3 12.4 7.4 28.5 14.7 15.3 16.1 20.9 22.7 14.4 25.1 45.3 19.8 31.5 21.8 25.6 17.8 30.9 26.7 31.5 45.9 33.9 18.3 28.4 20.9 16.7 35.5 24.0 31.3 33.8 15.9 39.2 132.6 28.7 20.3 15.3 25.7 22.0 18.1 16.9 15.5 21.3 42.3 27.9 16.5 25.9 31.6 21.4 41.8 18.4 22.1 34.5 14.6 30.4 28.1 18.8 28.3 27.2 22.2 19.2 11.3 14.6 17.7 17.9 13.4 19.3 23.9 12.1 17.6 22.2 31.5 24.2 52.3 31.0 49.7 38.8 18.1 17.9 32.5 21.9 0.0 0.5 10.0 1.6 1.1 1.1 0.4 1.2 1.2 0.8 0.3 0.7 0.8 48.8 1.0 0.8 0.4 2.7 0.5 26.0 24.6 25.7 29.0 25.4 30.0 29.1 28.7 33.5 22.2 28.5 25.1 12.9 9.6 7.9 6.5 7.5 25.6 8.6 4.4 6.8 39.8 8.4 6.6 6.0 10.0 6.8 1.8 27.1 10.6 21.2 27.0 0.0 4.1 3.8 6.1 7.0 9.1 3.0 9.3 10.2 2.8 7.1 7.1 4.6 12.7 1.3 5.9 7.9 12.0 7.3 18.5 10.2 3.9 2.0 8.5 17.0 2.1 6.2 11.0 10.6 5.6 26.6 5.7 12.3 4.0 6.3 8.0 25.6 3.8 8.3 19.3 10.4 2.2 4.6 35.3 0.0 7.1 6.2 3.5 11.4 14.6 36.2 6.2 17.4 8.0 7.0 34.7 ZDHHC19 MGC33345 ENSG00000163958 "Zinc finger DHHC-type palmitoyltransferase 19" Q8WVZ1 3 196197452-196211437 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 50.1" "Group enriched" "Detected in some" 17 "Early spermatids: 332.1;Late spermatids: 810.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "eosinophil: 1.2;memory B-cell: 2.5;naive B-cell: 2.4;neutrophil: 1.5" "Group enriched" "Detected in many" 20 "B-cells: 2.5;granulocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 37: B-cells - Transcription" "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.15e-1)" "unprognostic (7.50e-4)" "unprognostic (2.87e-3)" "unprognostic (6.72e-3)" "unprognostic (3.79e-1)" "unprognostic (1.59e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (3.66e-3)" "unprognostic (4.63e-2)" "unprognostic (6.52e-2)" "unprognostic (2.86e-2)" "unprognostic (3.46e-7)" "unprognostic (8.05e-4)" "unprognostic (4.71e-1)" "unprognostic (7.08e-3)" "unprognostic (4.28e-2)" 0.1 0.8 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.6 0.3 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 50.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 5.3 0.3 0.1 0.0 0.0 0.2 0.0 0.4 0.4 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 332.1 0.1 0.1 0.6 0.0 0.0 0.9 0.0 0.5 0.5 0.0 0.1 0.0 9.7 0.0 3.6 1.4 0.0 0.8 0.0 0.0 1.0 0.4 810.2 16.4 1.2 0.0 2.8 0.1 0.3 0.0 0.5 0.1 0.0 0.0 32.0 0.0 0.0 0.1 0.8 0.8 0.1 0.0 0.0 0.8 5.5 3.3 0.0 0.0 2.5 0.3 6.5 0.0 0.0 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZDHHC21 "DHHC21, DNZ1, HSPC097" ENSG00000175893 "Zinc finger DHHC-type palmitoyltransferase 21" Q8IVQ6 9 14611071-14693432 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 219.4;Inhibitory neurons: 201.6;Oligodendrocyte precursor cells: 268.9;Oligodendrocytes: 158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065254 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "HPA065254: AB_2685446" "unprognostic (2.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-2)" "unprognostic (2.01e-1)" "unprognostic (4.19e-2)" "unprognostic (2.58e-2)" "unprognostic (2.81e-2)" "unprognostic (1.13e-2)" "unprognostic (2.18e-2)" "unprognostic (8.37e-2)" "unprognostic (9.79e-3)" "unprognostic (3.97e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (8.87e-2)" "prognostic favorable (9.28e-6)" 3.7 5.7 4.7 4.6 5.8 2.5 6.2 12.7 6.7 6.2 2.2 4.7 6.8 4.9 6.1 8.5 4.5 3.5 5.1 6.0 4.5 4.9 2.6 5.2 6.6 3.4 3.3 5.2 4.7 4.8 6.5 4.2 3.7 5.2 5.2 10.6 4.6 3.7 4.5 8.7 7.2 4.1 3.4 5.5 4.3 4.1 3.5 2.6 6.1 3.4 6.1 4.2 6.7 4.7 7.1 3.6 6.9 4.6 1.1 1.2 5.3 8.9 2.7 3.1 3.5 1.8 3.3 7.0 2.1 6.2 3.9 4.5 4.8 2.9 4.4 14.1 3.7 29.9 8.3 3.5 3.6 5.3 9.5 2.3 6.6 3.6 2.3 5.7 18.4 2.8 2.5 0.8 5.5 3.9 1.2 5.1 4.8 3.0 6.7 0.0 3.3 3.5 9.6 7.8 4.2 11.3 4.1 5.0 2.8 5.3 6.3 8.6 13.2 2.2 3.3 2.2 8.3 2.8 5.6 0.0 4.6 0.3 2.3 0.2 0.1 0.0 0.4 0.3 0.4 2.0 0.4 0.4 0.0 1.4 0.3 0.4 0.0 1.1 0.2 0.5 0.6 0.2 4.7 5.8 12.7 6.7 6.0 4.5 3.4 3.3 3.7 3.4 3.5 4.7 18.0 22.4 24.1 132.9 46.6 9.6 9.3 8.1 13.1 45.1 23.0 14.1 23.2 24.3 18.2 44.1 43.8 8.8 27.7 31.9 5.9 16.0 5.3 18.1 23.5 18.4 15.6 7.2 219.4 17.9 7.1 14.0 26.5 24.6 10.8 36.7 32.9 10.1 11.1 37.0 201.6 14.6 10.2 15.5 8.2 7.7 19.3 11.8 1.8 107.7 17.7 65.7 41.2 268.9 158.2 35.9 14.1 31.2 20.8 12.4 46.7 11.3 12.7 49.4 6.6 19.7 15.3 22.3 26.6 24.4 20.0 7.7 14.4 10.5 13.9 16.1 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.3;Excitatory neurons: 8.8;Inhibitory neurons: 13.4;Late spermatids: 5.0;Oligodendrocyte precursor cells: 24.6" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 3.6;NTERA-2: 3.8;RH-30: 6.4;SCLC-21H: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 0.0 0.2 14.9 0.0 15.3 0.0 0.0 25.9 33.8 0.1 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 21.2 12.8 0.0 0.0 0.0 0.0 1.2 22.7 0.0 0.0 0.0 4.7 0.0 1.0 0.0 0.1 7.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.5 51.3 0.0 0.1 0.4 0.0 0.1 0.0 13.9 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 3.8 0.0 0.5 0.0 6.4 0.0 0.0 0.0 7.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 15.3 25.9 33.8 21.2 12.8 1.2 22.7 1.0 0.0 51.3 13.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 24.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type palmitoyltransferase 23" Q8IYP9 3 113947901-113965401 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 26.7;Excitatory neurons: 72.2;Late spermatids: 41.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 9 "amygdala: 5.4;basal ganglia: 7.3;cerebral cortex: 9.4;hippocampal formation: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA016808: AB_1859002" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (4.48e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.49e-1)" "unprognostic (3.98e-3)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (3.19e-1)" "unprognostic (6.63e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "prognostic favorable (1.48e-7)" "unprognostic (2.58e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (5.90e-4)" "unprognostic (3.29e-3)" 1.1 1.0 5.4 3.0 7.3 1.2 2.6 0.0 9.4 1.4 13.2 9.4 7.3 1.2 1.5 1.5 2.4 1.6 1.0 7.4 0.0 5.5 4.0 3.2 2.8 0.0 0.0 0.9 4.8 7.4 3.2 0.9 0.0 2.5 11.5 3.6 6.6 1.8 1.2 3.8 6.8 1.3 0.0 2.4 6.2 12.2 0.0 1.2 6.1 0.9 3.8 1.9 1.5 0.8 17.8 4.4 0.5 10.1 1.5 0.3 14.8 6.9 2.1 1.3 2.0 7.1 11.6 8.1 5.9 4.0 11.0 11.4 13.0 1.9 2.2 4.9 6.0 7.5 7.0 4.4 0.5 8.5 6.7 0.3 2.2 0.3 0.8 1.6 1.1 8.5 0.0 4.6 0.2 10.2 7.0 0.5 3.1 18.2 4.9 1.2 5.8 6.8 7.0 8.6 17.6 4.4 5.3 17.5 3.3 3.9 10.5 2.7 0.3 4.8 9.6 1.0 3.1 5.2 7.3 13.2 4.1 5.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 5.4 7.3 0.0 9.4 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.3 0.0 1.5 12.1 10.5 3.1 2.0 2.3 0.6 2.1 4.8 4.2 1.4 7.2 2.2 16.5 8.4 0.9 2.7 21.8 0.0 2.1 26.7 13.6 1.6 2.8 13.8 0.4 72.2 1.9 1.6 1.0 9.2 8.5 0.0 3.2 4.2 6.4 0.4 0.0 4.0 12.7 0.0 0.3 2.2 41.0 1.2 1.3 3.6 2.8 1.0 4.2 0.0 2.5 5.4 0.7 8.3 0.0 2.3 3.9 10.9 4.4 8.7 0.9 0.0 1.7 0.7 18.2 2.9 2.1 2.7 0.3 1.3 0.9 12.6 1.7 ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546235 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" 5.2 6.9 5.8 3.3 4.5 5.0 4.7 4.2 5.4 3.6 5.8 3.5 2.8 4.3 5.1 4.3 3.9 2.2 3.6 4.9 5.2 6.2 4.6 4.5 4.3 5.5 5.2 2.7 7.1 6.0 4.7 2.5 4.8 4.5 2.1 2.6 5.0 2.7 2.9 5.1 4.7 1.9 4.4 7.2 4.8 3.7 6.4 3.1 5.9 1.1 3.0 4.0 3.4 4.5 5.2 7.4 2.4 6.5 5.8 4.7 6.2 3.9 3.4 3.1 2.1 6.5 7.7 1.6 11.5 3.3 8.3 11.9 1.9 3.4 2.1 7.6 4.9 2.9 3.7 4.1 5.5 3.4 6.9 5.6 6.2 2.5 3.6 3.7 5.1 13.0 4.2 4.3 4.0 10.4 7.4 8.6 5.3 12.2 7.6 8.8 5.3 9.3 3.9 3.6 3.5 5.6 6.7 6.5 11.6 2.7 9.5 2.4 8.0 7.1 2.4 8.3 3.1 6.9 2.2 2.1 6.2 1.5 8.2 3.0 5.9 1.0 7.3 5.7 6.6 6.4 6.0 8.4 7.2 7.5 3.8 5.9 2.2 8.0 5.0 23.1 6.6 6.1 5.8 4.5 4.2 5.4 4.9 5.2 5.5 5.2 4.8 4.4 6.4 4.5 21.7 12.8 8.3 7.8 21.9 8.0 15.2 26.8 10.8 9.6 21.5 15.2 4.5 22.8 17.3 23.9 10.4 33.0 49.9 29.0 9.8 50.3 13.5 15.1 14.4 23.3 14.4 6.3 7.6 49.4 37.2 15.0 17.9 19.8 8.9 18.5 23.2 14.9 63.9 23.5 7.0 17.8 20.3 42.8 14.8 12.1 7.5 27.9 17.8 5.6 36.4 16.9 46.4 4.0 8.5 42.8 40.6 9.8 15.8 24.9 54.8 35.2 14.7 10.3 19.7 11.2 15.1 29.6 4.1 21.6 8.1 24.1 23.3 18.5 21.8 23.1 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 570.7;Late spermatids: 1564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 50.1 48.6 23.0 25.7 21.5 82.8 36.3 27.9 22.9 42.2 25.8 70.6 44.1 35.4 24.5 58.0 27.5 32.0 36.3 25.8 21.1 40.3 32.3 41.9 21.9 28.7 25.1 28.9 22.2 46.0 13.4 28.7 29.8 35.6 64.6 16.6 33.3 40.1 43.7 70.0 58.1 36.3 25.8 29.6 55.3 80.8 27.0 26.9 38.6 52.8 33.3 53.6 42.5 25.3 62.5 53.3 41.0 49.1 219.2 100.5 46.8 58.8 80.7 78.3 66.5 61.0 85.1 58.7 31.4 107.9 52.8 80.7 68.4 104.3 74.6 61.7 29.3 55.9 57.9 45.7 50.6 136.3 43.0 92.5 111.6 73.6 67.2 59.8 79.6 63.8 73.8 51.3 78.1 42.9 46.2 73.6 60.7 155.9 96.7 29.9 40.6 47.0 66.7 176.7 14.6 52.8 70.3 70.5 36.4 70.4 57.4 88.2 78.0 55.4 55.2 60.2 66.3 32.2 66.6 59.6 55.2 198.9 39.4 53.7 24.5 32.6 14.6 12.3 13.3 10.7 11.0 16.1 26.8 12.6 10.2 14.4 25.4 14.5 17.5 15.3 17.1 13.6 23.0 21.5 27.9 22.9 25.8 21.1 28.7 25.1 29.8 25.8 27.0 25.3 41.5 41.7 82.1 7.5 17.8 48.2 42.1 40.8 48.9 9.8 24.4 20.8 29.2 24.3 27.1 53.3 6.2 47.7 23.4 105.6 72.4 46.6 570.7 18.8 31.2 34.1 35.9 68.8 15.7 79.0 59.4 26.4 69.3 26.6 19.0 21.5 35.7 29.4 49.5 15.2 15.6 78.2 38.7 34.0 26.7 1564.3 51.9 37.4 24.9 18.7 35.6 25.1 34.0 15.1 11.2 115.8 73.1 44.8 26.2 73.7 112.9 30.1 20.9 10.6 19.7 15.6 31.9 104.5 45.3 70.5 60.2 101.7 25.0 26.1 72.8 128.9 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZDHHC6 "FLJ21952, ZNF376" ENSG00000023041 "Zinc finger DHHC-type palmitoyltransferase 6" Q9H6R6 10 112424428-112446917 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014357 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA014357: AB_2304658" "unprognostic (1.21e-1)" "unprognostic (1.00e-1)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.80e-1)" "unprognostic (2.07e-1)" "unprognostic (3.29e-2)" "unprognostic (6.24e-2)" "unprognostic (5.21e-1)" "unprognostic (3.54e-2)" "unprognostic (1.56e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (9.30e-2)" "unprognostic (8.87e-2)" "unprognostic (7.64e-2)" "unprognostic (1.22e-2)" 19.5 19.9 15.2 24.6 16.0 21.8 22.7 16.7 18.9 21.2 20.2 24.5 44.6 24.0 33.2 23.7 19.3 23.2 17.0 15.4 16.1 59.3 29.5 20.0 30.6 15.5 15.7 25.7 21.3 21.4 15.4 25.9 15.6 22.4 29.9 21.3 23.9 20.6 14.9 20.5 45.8 17.8 15.9 24.8 25.9 13.6 16.9 25.0 26.2 18.1 30.6 23.9 20.8 17.9 51.7 39.4 40.3 50.2 38.2 28.8 28.5 49.3 46.7 38.2 45.3 37.7 89.6 28.4 22.1 30.2 43.0 60.0 33.8 31.5 44.3 67.0 41.4 29.4 46.4 47.3 24.7 67.9 49.5 21.9 20.7 41.9 48.9 58.7 48.6 42.0 32.4 46.1 41.7 43.3 38.1 75.6 23.6 57.0 32.1 31.4 51.1 26.6 45.3 28.1 15.0 20.9 25.5 40.1 49.1 31.4 22.4 49.2 34.8 43.7 27.6 29.5 47.3 25.7 31.7 37.5 38.7 118.0 29.0 10.4 17.4 21.6 14.7 16.2 18.9 16.7 16.7 18.5 16.6 14.0 14.1 15.9 11.3 16.0 13.7 13.6 23.9 15.9 15.2 16.0 16.7 18.9 15.4 16.1 15.5 15.7 15.6 15.9 16.9 17.9 21.0 22.4 20.1 11.8 35.9 20.3 31.9 23.2 23.9 11.0 21.9 16.1 14.3 31.5 27.4 35.0 8.4 34.8 25.7 31.3 60.7 35.8 72.4 14.9 15.5 18.7 11.4 26.1 15.0 29.8 46.9 17.9 16.3 23.8 23.5 17.8 19.2 21.2 34.4 15.2 15.7 22.7 10.2 20.2 35.9 17.7 16.1 28.6 12.4 12.2 22.2 21.0 23.7 15.1 14.4 31.2 27.9 19.5 23.7 25.7 66.9 39.7 13.4 15.5 6.6 13.9 18.2 11.7 12.5 27.6 22.3 36.5 33.0 10.9 28.5 47.7 ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "HPA019215: AB_2670102, HPA059054: AB_2683892, HPA059642: AB_2684093" "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" 33.0 28.1 19.0 24.7 18.8 64.2 26.8 21.4 18.6 40.0 27.1 42.5 27.1 36.8 12.8 27.6 27.7 31.2 31.2 19.1 19.8 35.4 30.0 37.2 26.5 20.1 21.0 27.7 26.9 35.5 19.6 33.4 20.3 32.8 32.4 10.3 24.1 20.0 56.5 31.8 33.5 30.0 19.1 35.4 44.7 14.1 23.5 16.1 25.5 58.4 23.5 37.4 33.1 19.6 63.8 55.0 28.5 34.5 123.1 92.3 38.9 57.4 110.8 88.4 43.7 58.3 72.4 29.1 32.7 93.5 29.0 65.6 37.1 76.1 110.9 16.4 29.7 21.0 22.0 66.5 51.5 40.0 21.2 76.7 85.4 72.5 41.5 56.0 46.1 26.7 68.9 9.7 56.8 75.8 27.0 38.1 44.3 53.2 39.5 33.6 26.2 15.7 86.4 82.5 24.2 29.8 74.3 40.9 36.1 43.0 77.6 24.0 67.9 53.1 39.9 49.8 34.3 33.5 51.0 65.5 50.1 29.1 43.0 7.5 9.7 8.3 2.1 8.2 2.6 1.4 2.0 1.7 6.3 2.2 1.5 2.2 6.4 1.4 7.2 4.3 0.5 3.6 19.0 18.8 21.4 18.6 19.1 19.8 20.1 21.0 20.3 19.1 23.5 19.6 13.3 32.1 25.2 12.1 10.8 13.3 21.5 25.4 17.1 9.2 16.2 13.2 22.5 12.8 17.9 16.5 6.2 18.5 15.7 37.7 1.9 14.1 9.7 15.5 20.1 12.2 12.6 11.6 16.4 15.6 24.9 23.0 28.5 29.1 3.8 14.3 15.0 11.6 28.1 15.2 16.2 29.4 14.2 46.8 26.7 10.9 17.4 36.2 16.0 19.7 42.9 5.9 21.6 13.6 14.7 30.0 33.9 21.1 15.2 26.2 22.1 9.5 32.6 6.7 13.1 13.7 14.9 8.3 13.0 20.1 12.8 16.1 13.4 6.8 34.7 35.3 ZDHHC8 "KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" 31.6 31.2 13.8 18.6 15.1 10.7 30.4 11.3 26.4 32.6 0.0 22.8 12.1 31.2 7.5 29.3 27.7 13.0 31.6 13.9 7.0 30.4 36.1 31.0 17.1 12.2 10.0 34.6 35.6 14.4 41.3 16.9 9.9 28.1 7.0 7.4 27.6 15.4 23.6 32.2 24.7 13.1 6.6 35.7 26.4 14.9 12.3 13.7 37.3 10.3 11.7 25.3 30.9 12.8 30.0 18.7 29.3 38.7 42.0 25.0 26.3 55.1 37.3 36.6 32.6 9.8 15.2 0.1 22.3 46.0 19.8 40.2 15.5 42.2 18.0 43.2 59.4 14.5 57.2 23.0 34.5 0.0 19.5 43.7 27.9 28.2 23.6 22.5 41.4 21.0 101.4 22.8 33.0 14.7 17.8 39.1 14.9 13.2 29.4 37.8 25.6 10.9 15.6 35.9 46.9 23.7 22.4 10.7 26.6 13.1 0.7 20.4 48.0 82.5 59.8 46.8 25.0 32.6 11.5 11.7 24.2 18.7 24.8 1.3 0.4 0.1 0.8 0.5 0.4 0.2 0.2 0.4 0.1 0.5 0.4 0.5 0.0 0.4 0.2 1.3 0.7 0.2 13.8 15.1 11.3 26.4 13.9 7.0 12.2 10.0 9.9 6.6 12.3 12.8 17.4 3.2 3.1 17.6 3.7 9.1 3.8 3.6 5.7 11.9 8.2 8.1 7.1 4.3 3.5 11.0 14.6 3.6 9.2 4.3 1.9 5.2 0.5 4.3 15.7 11.5 4.2 0.8 16.6 4.5 8.5 9.3 10.2 8.7 5.7 8.7 10.4 9.8 4.9 13.5 9.9 5.9 10.2 5.0 5.0 2.1 10.8 5.7 5.4 9.4 3.7 7.4 1.0 13.0 13.3 7.7 5.4 14.7 2.7 7.6 2.7 2.1 1.5 10.8 6.6 10.5 6.8 1.4 3.8 5.5 9.8 3.4 4.2 8.0 5.0 3.4 ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Oligodendrocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 28.2 12.0 39.2 10.2 66.6 5.4 24.3 46.5 52.5 19.1 23.3 22.0 31.6 11.8 11.7 15.6 12.1 15.3 15.5 39.2 49.0 37.1 40.1 26.7 3.3 60.5 58.2 11.2 25.9 25.2 11.4 17.2 52.5 18.8 24.9 6.0 21.1 11.3 13.4 35.3 34.0 15.3 44.8 3.9 19.5 4.1 57.8 3.6 13.8 11.3 6.6 23.8 14.5 78.6 45.9 23.8 33.2 67.5 112.4 87.7 27.0 44.3 50.6 20.9 26.0 37.6 58.4 1.6 73.7 47.6 54.0 30.4 38.0 44.6 30.0 2.6 23.7 9.2 24.0 50.1 44.4 6.1 15.7 96.0 71.1 34.0 50.1 36.5 39.9 15.0 10.1 17.6 34.0 40.0 8.8 11.4 18.0 102.3 40.4 8.2 21.4 27.1 30.1 25.2 26.3 22.0 12.7 64.7 20.5 38.9 27.6 10.1 32.8 21.1 7.3 50.0 36.3 16.5 12.7 5.5 37.9 25.1 10.8 0.0 2.2 1.8 3.0 2.0 3.7 2.7 3.6 2.9 2.4 1.5 4.5 2.6 0.0 2.5 5.2 5.1 1.8 2.1 39.2 66.6 46.5 52.5 39.2 49.0 60.5 58.2 52.5 44.8 57.8 78.6 66.0 22.4 28.6 4.6 2.8 18.6 12.4 12.8 13.1 9.1 16.8 15.1 4.6 17.2 15.9 46.0 2.1 5.6 2.7 20.1 3.9 18.6 1.8 23.8 16.9 16.6 18.0 4.2 10.5 19.8 19.1 32.7 18.3 59.7 2.5 11.5 7.9 43.7 4.9 1.7 11.8 23.2 10.2 3.5 12.2 2.0 12.2 3.9 10.6 7.5 0.3 1.5 1.0 9.5 118.2 33.5 14.6 7.5 7.7 39.1 51.0 25.8 7.2 2.8 0.0 9.5 11.1 8.4 8.7 16.9 19.2 10.3 5.1 7.5 27.2 22.1