Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ALAD	"ALADH, PBGS"	ENSG00000148218	"Aminolevulinate dehydratase"	P13716	9	113386312-113401290	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	"Allosteric enzyme, Lyase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 209.8"	"Cell type enhanced"	"Detected in all"		"Erythroid cells: 147.8;Granulosa cells: 86.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA021023, HPA022124"	Enhanced		Approved	Cytosol		NA	NA		44000000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 35: Non-specific - Unknown function"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol		"HPA021023: AB_1844716, HPA022124: AB_1844717"	"unprognostic (2.75e-1)"	"unprognostic (6.26e-2)"	"prognostic unfavorable (7.33e-5)"	"prognostic favorable (5.64e-4)"	"unprognostic (4.16e-2)"	"unprognostic (9.49e-2)"	"prognostic favorable (8.80e-5)"	"unprognostic (2.87e-3)"	"unprognostic (3.49e-1)"	"unprognostic (2.95e-1)"	"unprognostic (1.62e-1)"	"unprognostic (3.31e-2)"	"prognostic favorable (1.65e-4)"	"unprognostic (1.75e-1)"	"unprognostic (1.22e-1)"	"unprognostic (3.40e-1)"	"unprognostic (1.31e-2)"	54.7	153.9	73.5	16.8	82.7	82.2	23.2	75.2	84.7	18.4	53.6	25.7	29.5	16.3	26.6	35.0	15.6	27.4	51.9	66.0	74.5	73.2	209.8	20.6	15.6	85.4	83.5	28.9	46.5	73.2	15.9	24.9	84.5	34.1	24.5	19.0	98.6	24.2	28.8	38.9	26.6	17.6	80.1	13.6	50.4	13.1	81.1	20.3	25.9	23.9	18.7	18.4	19.3	83.7	8.1	14.8	11.0	15.7	71.2	48.4	67.8	21.9	35.4	13.7	17.2	19.2	16.7	11.7	12.7	30.3	11.0	29.1	8.1	14.6	8.3	29.5	10.2	22.0	18.2	26.2	16.4	21.2	19.0	41.2	10.8	12.7	5.5	53.9	27.1	18.6	8.9	16.5	23.7	61.8	23.8	21.2	5.4	57.9	27.4	19.5	18.7	19.8	21.4	16.6	10.2	9.4	27.2	32.5	20.1	19.2	34.1	23.7	30.7	12.5	9.3	25.1	12.4	23.8	26.0	9.8	34.1	18.9	13.6	10.2	13.7	23.6	11.3	15.5	6.0	6.8	9.3	6.0	14.6	10.2	8.7	9.9	6.2	6.9	17.4	6.0	10.8	9.7	73.5	82.7	75.2	84.7	66.0	74.5	85.4	83.5	84.5	80.1	81.1	83.7	7.2	16.0	15.6	18.6	10.4	7.0	8.9	7.1	8.0	12.9	16.7	11.6	50.3	25.8	12.0	14.7	27.1	48.2	7.4	27.7	13.7	20.3	5.4	17.7	9.2	11.5	9.1	147.8	10.0	26.3	23.2	10.2	15.3	27.7	14.5	86.5	11.0	70.0	17.0	5.0	10.7	12.5	10.2	15.1	6.4	10.8	11.8	12.4	12.4	9.4	12.4	6.4	8.2	7.1	20.0	15.0	35.3	14.7	11.0	7.6	32.6	59.0	10.6	15.7	6.6	8.9	24.6	6.8	9.5	22.6	9.1	11.4	8.8	11.7	16.7	9.2
ALAS1	"ALAS, ALAS3"	ENSG00000023330	"5'-aminolevulinate synthase 1"	P13196	3	52198086-52214327	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Heme biosynthesis"	"Acyltransferase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"adrenal gland: 720.5;liver: 548.8"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 243.1;Syncytiotrophoblasts: 309.2;Theca cells: 187.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 233.9"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 233.9"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017498, HPA035860"	Enhanced		Supported	Nucleoplasm,Mitochondria		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 15: Hepatocytes - Hemostasis"	Mitochondria	Nucleoplasm	"CAB017498: AB_2225629, HPA035860: AB_10672992"	"unprognostic (1.17e-1)"	"unprognostic (1.65e-1)"	"unprognostic (1.50e-1)"	"unprognostic (7.09e-2)"	"unprognostic (2.33e-1)"	"unprognostic (6.21e-2)"	"prognostic favorable (1.82e-5)"	"unprognostic (3.98e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.31e-2)"	"unprognostic (9.86e-2)"	"unprognostic (5.64e-2)"	"prognostic favorable (6.06e-7)"	"unprognostic (8.45e-2)"	"unprognostic (3.91e-2)"	"unprognostic (1.07e-1)"	"unprognostic (1.75e-2)"	34.5	720.5	24.8	23.9	25.1	176.7	28.7	37.9	82.5	20.5	35.7	43.6	44.9	19.0	28.1	36.4	15.3	32.7	116.2	26.6	28.1	45.7	548.8	47.8	22.9	27.2	25.4	17.1	19.6	60.3	15.7	36.8	33.2	23.1	41.6	20.6	42.8	27.2	110.9	24.3	39.3	23.9	24.9	19.5	45.9	18.6	31.8	23.5	22.1	106.6	28.2	73.8	23.5	28.3	36.2	55.0	38.0	35.4	57.9	43.1	103.1	51.8	47.7	67.6	65.3	73.6	66.2	33.6	12.7	36.4	137.0	20.9	55.1	42.6	54.7	65.9	21.6	43.2	41.2	56.4	81.8	70.8	83.0	54.0	39.1	107.7	35.7	25.0	62.8	57.7	25.8	27.0	62.4	29.5	33.9	107.3	33.0	41.1	93.4	20.0	23.9	53.3	59.8	213.9	20.2	13.3	83.9	40.9	47.2	30.5	23.5	99.9	45.7	37.6	37.1	78.5	76.2	39.5	73.8	50.5	42.1	75.5	61.1	233.9	33.4	103.2	22.9	42.9	37.4	23.1	23.9	26.0	29.8	21.5	21.1	23.3	49.6	30.9	39.0	17.1	35.7	25.1	24.8	25.1	37.9	82.5	26.6	28.1	27.2	25.4	33.2	24.9	31.8	28.3	28.4	35.3	60.3	5.2	14.9	17.3	17.2	36.1	15.9	16.6	28.6	19.6	107.5	25.8	37.7	23.9	4.2	81.9	25.1	68.5	56.7	35.5	10.2	20.2	9.3	27.6	34.6	11.2	6.2	31.3	28.2	19.6	42.3	25.3	95.4	13.1	18.5	243.1	69.1	11.8	6.2	24.3	34.6	13.0	20.8	4.1	13.4	36.4	5.4	8.4	49.1	9.7	11.3	4.0	8.4	42.3	28.1	16.6	14.0	16.0	35.6	36.1	40.6	9.2	13.1	9.1	27.5	25.5	22.3	21.4	16.2	309.2	25.1	187.2	24.3	26.4
ALAS2	ASB	ENSG00000158578	"5'-aminolevulinate synthase 2"	P22557	X	55009055-55030977	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis"	"Acyltransferase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	13	"bone marrow: 606.2"	"Cell type enriched"	"Detected in some"	166	"Erythroid cells: 2366.7"	"Cancer enhanced"	"Detected in single"		"renal cancer: 0.6"	"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in single"	6	"plasmacytoid DC: 1.6"	"Lineage enriched"	"Detected in single"	6	"dendritic cells: 1.6"	"Group enriched"	"Detected in some"	93	"HEL: 71.7;K-562: 85.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"				"unprognostic (7.82e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.41e-2)"	"unprognostic (1.14e-2)"	"unprognostic (2.98e-3)"	"unprognostic (5.59e-2)"	"unprognostic (1.37e-1)"	"unprognostic (1.47e-1)"	"unprognostic (8.68e-2)"	"unprognostic (4.07e-2)"	"unprognostic (2.72e-1)"	"unprognostic (3.45e-1)"	"unprognostic (2.32e-2)"	"unprognostic (6.63e-3)"	"unprognostic (4.39e-1)"	"unprognostic (1.23e-1)"	"unprognostic (1.89e-1)"	1.9	0.5	0.9	0.4	0.9	606.2	0.6	0.8	2.5	0.2	1.6	0.5	0.6	0.1	0.0	0.8	1.1	0.8	3.4	0.7	0.8	2.5	3.2	5.2	0.3	1.8	1.2	0.4	0.3	0.0	1.2	44.9	1.6	0.2	0.0	0.2	1.0	0.2	0.5	0.6	0.3	0.1	1.6	25.2	0.2	0.2	1.0	1.0	1.2	18.2	0.0	0.6	0.7	1.3	0.1	0.0	0.0	0.8	0.1	0.0	0.5	0.0	0.0	0.0	0.0	0.2	0.3	0.2	0.1	0.0	0.0	0.6	0.0	0.0	0.0	0.1	0.6	71.7	0.0	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	85.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.4	0.0	0.2	0.2	0.1	0.4	0.0	0.2	0.1	0.0	0.4	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.6	0.4	0.1	0.1	0.3	0.1	0.0	0.0	0.0	0.1	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	1.6	0.0	5.9	0.9	0.9	0.8	2.5	0.7	0.8	1.8	1.2	1.6	1.6	1.0	1.3	0.1	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	4.3	0.0	0.0	0.0	0.4	0.0	0.0	0.0	4.8	0.0	0.1	0.0	0.3	1.8	2366.7	0.0	0.2	1.8	0.3	0.0	0.1	0.0	0.0	1.4	1.3	2.1	0.0	0.0	0.0	0.0	5.8	0.0	0.0	0.0	7.3	14.2	1.0	0.0	0.0	1.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.4	0.5	0.0	0.0	0.0	0.0	0.7	1.1	0.0	0.0	0.1
BLVRA	BLVR	ENSG00000106605	"Biliverdin reductase A"	P53004	7	43758680-43807342	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hofbauer cells: 259.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019709, HPA042865, HPA054322"	Approved		Supported	Cytosol		NA	NA		1200000	"Cluster 7: Monocytes - Unknown function"	"Cluster 68: Epididymis - Unknown function"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 4: Macrophages - Innate immune response"	Cytosol		"HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450"	"unprognostic (2.47e-2)"	"unprognostic (8.38e-3)"	"unprognostic (1.79e-2)"	"unprognostic (2.16e-3)"	"unprognostic (6.45e-3)"	"unprognostic (5.01e-2)"	"unprognostic (1.63e-2)"	"prognostic favorable (8.65e-4)"	"unprognostic (1.42e-1)"	"unprognostic (1.75e-2)"	"unprognostic (2.93e-1)"	"unprognostic (9.27e-2)"	"unprognostic (1.15e-2)"	"unprognostic (5.63e-3)"	"unprognostic (3.18e-1)"	"unprognostic (2.13e-3)"	"unprognostic (4.56e-2)"	53.2	28.0	31.4	39.7	33.4	65.6	49.9	32.0	40.1	44.3	31.4	61.4	12.5	38.5	129.9	67.5	40.9	33.4	52.7	32.3	34.7	41.3	14.6	62.7	58.6	34.1	33.6	46.6	23.5	54.9	26.2	28.9	34.2	38.4	19.8	25.4	36.5	46.0	59.7	33.4	27.7	54.1	33.1	82.0	35.3	13.1	34.0	43.0	31.3	69.3	52.6	43.5	40.4	32.0	48.6	92.2	26.2	110.5	55.0	72.7	1.3	32.3	99.3	54.0	65.4	22.2	28.3	0.3	60.6	51.5	190.7	62.1	82.1	81.7	46.2	227.3	56.8	104.1	86.6	138.1	139.5	11.8	37.5	49.9	135.7	57.2	37.8	108.5	92.7	51.1	70.2	55.7	41.4	52.5	37.0	6.3	35.9	11.0	104.7	80.4	45.6	261.4	121.1	26.6	34.0	104.4	65.9	65.1	55.2	46.2	146.7	77.7	57.0	49.3	53.9	21.8	56.0	74.7	63.2	0.2	80.8	46.9	78.4	51.1	291.9	169.2	39.1	374.9	36.7	26.9	75.7	64.9	135.4	17.0	39.7	31.0	26.5	22.4	368.4	20.1	82.2	208.5	31.4	33.4	32.0	40.1	32.3	34.7	34.1	33.6	34.2	33.1	34.0	32.0	22.0	60.9	85.0	7.5	10.7	29.1	64.2	102.4	34.1	18.0	29.6	36.1	59.4	17.2	75.7	35.0	2.1	9.7	9.3	0.3	56.7	52.6	0.7	31.6	20.2	27.3	0.0	74.7	8.4	35.1	8.1	39.7	8.2	41.4	111.5	17.2	24.3	1.9	259.1	8.4	11.5	0.4	59.0	136.5	53.7	1.6	37.0	80.4	46.2	2.8	147.3	36.6	13.4	7.5	4.3	25.2	1.2	29.0	16.6	87.9	7.1	110.5	69.6	13.0	46.0	23.0	50.6	3.0	14.2	52.9	34.4	5.2	23.4	4.9	0.6	48.7
BLVRB	"FLR, SDR43U1"	ENSG00000090013	"Biliverdin reductase B"	P30043	19	40447765-40465764	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 625.2"	"Cell type enhanced"	"Detected in all"		"Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"classical monocyte: 465.2"	"Group enriched"	"Detected in all"	7	"dendritic cells: 343.3;monocytes: 465.2"	"Cell line enhanced"	"Detected in many"		"A549: 506.6;K-562: 506.8;OE19: 451.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041698, HPA041937"	Enhanced		Supported	"Nucleoplasm,Vesicles,Plasma membrane,Cytosol"		No	No		370000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Nucleoplasm, Vesicles, Plasma membrane"	"HPA041698: AB_10796781, HPA041937: AB_10794308"	"unprognostic (1.86e-1)"	"unprognostic (1.14e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.46e-1)"	"unprognostic (9.92e-2)"	"unprognostic (1.20e-2)"	"unprognostic (8.56e-2)"	"unprognostic (1.35e-1)"	"prognostic unfavorable (3.90e-4)"	"unprognostic (2.30e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.02e-1)"	"unprognostic (5.11e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.92e-2)"	115.7	76.8	46.6	48.2	46.9	625.2	93.8	49.4	61.0	86.2	52.1	78.5	75.1	59.0	20.5	188.8	69.3	50.9	125.6	44.5	48.0	103.1	266.2	102.8	58.9	56.0	48.6	66.7	73.2	46.1	25.2	52.1	58.5	74.3	30.3	5.5	89.4	42.2	210.4	83.9	72.2	31.7	49.8	166.7	138.4	10.2	52.3	27.5	64.5	94.1	25.3	81.0	96.5	53.4	227.9	506.6	7.3	77.7	73.7	70.2	57.3	28.0	88.7	39.3	75.4	103.4	203.8	74.3	212.3	56.3	126.8	73.1	30.4	64.6	10.5	123.8	20.0	114.9	73.4	62.4	169.8	1.6	32.2	69.2	119.4	52.4	34.2	40.1	41.8	27.4	506.8	137.0	51.0	359.2	6.1	7.2	1.9	451.4	133.8	54.0	23.4	120.3	50.9	146.5	0.4	10.5	84.5	224.5	84.4	13.2	221.5	17.6	39.2	99.4	103.9	156.4	15.9	71.7	92.1	28.5	259.1	46.2	39.0	45.5	465.2	18.0	29.2	220.9	27.0	58.2	24.3	24.5	343.3	37.5	24.7	19.3	58.4	27.4	117.7	75.8	37.3	259.4	46.6	46.9	49.4	61.0	44.5	48.0	56.0	48.6	58.5	49.8	52.3	53.4	74.6	221.2	164.5	9.4	34.4	129.4	348.5	337.9	103.6	11.2	93.8	143.0	130.5	164.5	184.2	97.5	6.2	84.9	39.5	343.6	266.1	234.2	10.0	56.5	46.3	51.1	44.9	3131.8	5.2	267.3	94.7	112.5	280.3	83.1	43.1	31.0	57.1	680.8	1099.2	10.1	5.1	223.5	158.7	627.7	165.4	23.6	124.2	286.7	144.1	13.1	219.8	88.0	32.0	2.0	5.6	260.4	464.0	94.0	25.7	229.7	864.3	488.3	139.1	13.5	32.9	65.4	146.0	2.6	4.0	160.3	130.4	74.7	34.5	34.7	191.0	260.5
CP		ENSG00000047457	Ceruloplasmin	P00450	3	149162410-149221829	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters"	"Copper transport, Ion transport, Transport"	Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"liver: 1871.4"	"Cell type enhanced"	"Detected in many"		"Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4"	"Cancer enhanced"	"Detected in many"		"liver cancer: 98.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	10	"EFO-21: 318.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001834, CAB008591"	Supported				"Secreted to blood"	NA	NA	160000000000	440000000000		"Cluster 62: Liver - Hemostasis"	"Cluster 38: EFO-21 - Unknown function"	"Cluster 15: Hepatocytes - Hemostasis"			"CAB008591: AB_1613734, HPA001834: AB_1078502"	"unprognostic (3.58e-1)"	"unprognostic (4.24e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.80e-2)"	"unprognostic (4.14e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.06e-1)"	"unprognostic (2.97e-2)"	"unprognostic (2.07e-1)"	"unprognostic (8.75e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.70e-1)"	"prognostic unfavorable (1.14e-7)"	"unprognostic (2.68e-2)"	"unprognostic (1.59e-1)"	"unprognostic (2.00e-1)"	"unprognostic (2.70e-1)"	13.0	2.3	17.9	2.2	18.1	0.9	20.8	18.7	29.8	70.2	129.2	13.0	9.8	14.8	0.0	5.6	8.3	1.1	39.2	17.5	33.0	9.5	1871.4	13.4	18.9	28.1	20.3	0.8	6.5	3.9	28.6	3.4	24.9	7.9	16.4	246.5	39.9	0.9	2.6	13.0	20.8	2.4	19.2	23.1	3.0	1.5	20.1	0.5	16.1	8.3	20.0	23.9	2.3	29.0	0.2	18.8	15.6	0.0	3.3	0.1	0.1	0.0	0.2	0.0	0.0	0.1	0.1	0.1	318.8	0.0	29.4	0.1	0.2	0.0	0.0	0.2	0.2	0.0	0.4	32.7	0.0	0.4	0.0	0.1	0.0	0.0	0.1	0.5	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.2	2.5	5.4	0.0	0.0	0.0	0.4	6.7	16.2	0.0	0.2	0.3	1.0	0.1	0.4	0.0	0.4	0.0	0.2	1.7	0.2	0.2	0.0	0.0	0.9	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	17.9	18.1	18.7	29.8	17.5	33.0	28.1	20.3	24.9	19.2	20.1	29.0	2.3	19.2	76.6	3.3	10.6	3.3	8.3	28.6	0.6	6.9	14.0	0.6	0.6	65.8	558.1	9.2	6.2	0.1	0.3	0.1	0.0	83.4	0.9	190.5	51.0	12.6	0.0	34.7	1.5	21.4	0.2	16.3	0.0	406.0	2.5	0.1	34.6	1687.2	0.6	5.0	1.4	0.2	8.2	44.6	6.9	1.2	0.3	4.0	0.0	6.5	1.6	720.5	1.0	0.5	2.0	69.3	0.0	0.4	0.3	19.5	0.0	0.3	318.4	24.8	0.0	0.8	15.3	0.0	0.1	0.8	2.6	0.3	4.9	0.1	0.1	79.0
CPNE7		ENSG00000178773	"Copine 7"	Q9UBL6	16	89575758-89597246	"Metabolic proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 28.0;epididymis: 19.3;pituitary gland: 14.1"	"Cell type enhanced"	"Detected in some"		"Bipolar cells: 11.2;Collecting duct cells: 20.2;Excitatory neurons: 9.3;Inhibitory neurons: 9.1;Spermatogonia: 10.2;T-cells: 9.5"	"Cancer enhanced"	"Detected in many"		"colorectal cancer: 11.9"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"MAIT T-cell: 4.9"	"Lineage enriched"	"Detected in single"	5	"T-cells: 4.9"	"Cell line enhanced"	"Detected in many"		"HHSteC: 103.2;TIME: 58.8"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA043359	Uncertain					NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 7: Non-specific - Mitochondria"			"HPA043359: AB_10794884"	"unprognostic (6.77e-2)"	"unprognostic (1.30e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.97e-1)"	"unprognostic (3.08e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.82e-1)"	"unprognostic (2.28e-3)"	"unprognostic (2.55e-1)"	"unprognostic (6.47e-2)"	"unprognostic (5.88e-2)"	"unprognostic (6.93e-2)"	"prognostic unfavorable (9.52e-6)"	"unprognostic (1.87e-2)"	"unprognostic (1.17e-1)"	"unprognostic (3.08e-1)"	"prognostic favorable (7.22e-4)"	0.5	0.4	13.5	0.9	13.2	0.9	1.5	0.0	17.6	1.4	0.0	0.7	3.6	0.6	19.3	2.1	2.1	3.3	0.4	15.1	11.4	4.3	1.2	1.7	0.5	2.6	16.2	0.5	0.9	2.4	14.1	0.3	7.4	1.8	0.1	1.6	1.4	6.1	0.0	1.6	3.4	0.2	1.0	0.8	3.2	4.1	28.0	1.6	0.8	0.1	0.4	1.6	1.3	6.0	0.1	24.7	0.2	0.4	40.8	41.8	0.3	10.7	4.5	14.6	11.2	24.8	20.7	0.0	9.5	4.2	0.5	16.8	15.4	0.7	5.0	6.0	12.2	0.2	21.5	0.5	103.2	0.1	4.1	16.3	1.1	7.7	29.0	49.3	0.2	17.4	27.3	0.3	35.1	3.8	8.0	4.8	16.1	15.6	19.1	0.4	0.0	17.6	2.2	0.1	13.7	0.2	3.6	5.2	1.1	0.3	4.6	3.2	58.8	28.4	0.0	17.7	0.0	0.1	0.0	5.0	27.8	17.3	12.0	0.0	0.0	0.1	0.7	0.0	4.9	0.0	1.1	1.8	0.0	0.0	0.0	0.1	0.0	0.9	0.0	0.0	0.2	0.2	13.5	13.2	0.0	17.6	15.1	11.4	2.6	16.2	7.4	1.0	28.0	6.0	0.5	0.0	0.6	1.3	0.1	2.3	1.1	0.1	0.6	11.2	3.9	5.2	0.8	1.5	0.8	20.2	0.0	0.0	1.4	0.1	0.0	0.9	0.0	1.0	0.5	0.7	0.0	0.4	9.3	0.2	0.2	0.3	3.1	2.2	0.0	0.1	0.4	0.0	0.1	0.0	9.1	0.3	0.0	0.0	0.4	0.6	0.3	0.9	1.8	0.0	0.0	0.3	0.0	3.5	0.6	0.6	0.0	0.7	0.1	1.2	0.7	1.7	0.2	0.9	0.0	0.3	0.5	0.3	10.2	1.2	1.1	0.0	9.5	0.0	1.9	2.1
CPOX	"CPO, CPX, HCP"	ENSG00000080819	"Coproporphyrinogen oxidase"	P36551	3	98579446-98593648	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Oxidoreductase	"Disease variant, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 352.8;Extravillous trophoblasts: 75.9;Oligodendrocytes: 99.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in all"		"HEL: 166.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015736, HPA054448"			Supported	Mitochondria		No	No		170000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 36: HEL - Hemostasis"	"Cluster 6: Erythroid cells - Oxygen transport"	Mitochondria		"HPA015736: AB_1847194, HPA054448: AB_2682490"	"unprognostic (2.14e-1)"	"unprognostic (1.04e-1)"	"unprognostic (4.07e-2)"	"unprognostic (6.09e-2)"	"unprognostic (2.71e-1)"	"unprognostic (2.34e-2)"	"unprognostic (8.58e-3)"	"unprognostic (7.14e-2)"	"unprognostic (2.53e-2)"	"unprognostic (2.01e-1)"	"unprognostic (1.10e-2)"	"unprognostic (1.86e-2)"	"prognostic unfavorable (1.04e-5)"	"unprognostic (1.62e-1)"	"unprognostic (2.67e-2)"	"unprognostic (2.15e-2)"	"unprognostic (2.57e-1)"	8.1	10.0	19.7	11.4	28.2	44.1	7.2	24.0	31.7	9.1	13.5	10.0	21.2	10.1	7.2	16.1	7.4	8.1	8.6	19.5	22.4	6.5	35.3	7.5	12.3	30.8	24.9	10.7	7.2	9.5	5.4	18.0	29.8	8.4	12.0	4.5	7.6	7.9	11.2	13.1	15.2	9.0	24.5	9.5	9.4	4.7	25.1	12.8	7.1	9.8	12.3	8.1	10.9	41.8	47.9	22.9	19.9	35.4	36.5	26.9	56.6	30.0	21.7	30.7	34.7	38.2	14.7	5.0	33.1	16.2	33.6	34.1	24.9	32.8	51.9	15.4	21.6	166.4	12.9	49.9	18.5	35.7	37.8	21.2	27.0	29.0	12.0	35.9	29.6	20.2	32.2	20.9	29.1	14.8	36.2	30.4	23.4	26.6	41.0	25.4	45.0	22.1	26.2	19.8	13.1	13.0	32.0	10.9	96.2	22.1	16.7	22.5	24.9	45.1	44.0	26.1	22.4	31.6	26.8	26.7	44.6	38.3	33.7	0.0	0.6	0.0	0.3	0.3	0.7	0.5	0.6	0.8	0.5	0.5	0.2	0.8	0.0	0.6	0.2	0.3	0.3	0.2	19.7	28.2	24.0	31.7	19.5	22.4	30.8	24.9	29.8	24.5	25.1	41.8	6.4	3.2	8.7	9.1	5.6	7.4	3.9	7.3	11.4	4.3	6.0	4.6	8.0	7.2	4.2	3.7	8.4	23.9	6.5	7.9	1.9	3.7	0.1	5.2	8.6	7.4	8.4	352.8	17.7	1.7	75.9	9.4	10.2	5.0	1.3	7.0	11.7	36.4	12.7	0.0	12.3	9.1	4.1	11.3	10.0	0.2	7.5	11.4	12.4	11.2	12.7	5.8	3.1	13.0	99.1	3.2	4.1	7.9	10.4	5.2	9.4	6.3	5.0	5.0	13.1	6.4	7.2	0.3	6.1	12.2	10.2	10.7	12.7	9.7	9.9	4.2
CYBRD1	"CYB561A2, DCYTB, FLJ23462, FRRS3"	ENSG00000071967	"Cytochrome b reductase 1"	Q53TN4	2	171522247-171558129	"Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport"	"Oxidoreductase, Translocase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7"	"Group enriched"	"Detected in many"	4	"dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7"	"Cell line enhanced"	"Detected in many"		"ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA014757	Approved		Supported	"Plasma membrane"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 45: Enterocytes - Digestion"	"Plasma membrane"		"HPA014757: AB_1847374"	"unprognostic (1.35e-1)"	"unprognostic (1.57e-1)"	"unprognostic (2.89e-2)"	"unprognostic (4.87e-2)"	"unprognostic (2.97e-2)"	"unprognostic (3.11e-2)"	"unprognostic (2.86e-1)"	"unprognostic (5.44e-3)"	"unprognostic (8.90e-3)"	"unprognostic (3.57e-3)"	"unprognostic (1.74e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.02e-3)"	"unprognostic (1.93e-2)"	"unprognostic (8.48e-2)"	"unprognostic (2.77e-2)"	"unprognostic (1.51e-2)"	166.7	97.5	32.6	24.4	38.8	18.3	148.7	33.9	34.1	140.0	32.6	68.7	197.7	100.2	49.7	70.6	88.2	153.7	128.6	28.2	45.9	32.0	21.7	129.9	33.8	45.2	38.7	180.9	21.6	12.0	26.1	38.1	40.5	70.6	39.0	22.2	63.7	76.7	23.3	85.0	233.4	87.9	35.6	30.6	53.3	23.8	35.9	27.9	231.0	82.8	30.1	84.3	90.4	43.0	24.8	18.1	10.1	19.2	1064.0	453.8	1.3	88.3	408.2	45.0	56.4	1.1	33.8	0.0	14.8	214.2	46.2	12.2	8.4	7.2	53.2	18.9	2.2	20.7	26.1	0.4	222.7	22.0	1.9	327.3	68.8	70.5	13.7	276.3	29.6	12.4	7.0	0.2	128.3	0.0	7.1	20.4	5.1	0.0	4.6	2.5	125.3	1.5	7.0	1.4	1.3	4.7	104.2	0.2	56.5	3.6	35.8	13.5	59.5	101.0	14.4	96.1	38.3	0.3	0.4	0.2	49.5	18.3	55.6	0.0	17.4	0.8	1.6	17.7	0.3	0.0	0.3	0.2	16.8	0.0	0.0	0.0	9.8	3.6	13.7	0.7	0.0	7.5	32.6	38.8	33.9	34.1	28.2	45.9	45.2	38.7	40.5	35.6	35.9	43.0	37.6	221.2	109.0	45.1	0.9	121.2	47.3	20.3	38.7	0.0	54.7	48.0	18.4	37.1	34.7	25.8	0.0	1.9	3.4	16.1	0.0	1.0	1.5	4.2	35.6	33.9	0.0	85.0	0.9	6.4	2.3	243.4	13.3	8.3	2.5	1.6	73.5	2.4	48.5	0.0	1.5	22.2	2.0	60.7	92.0	6.1	202.0	28.4	44.4	36.5	29.3	27.9	4.1	12.1	54.2	1.8	16.2	221.5	2.2	22.5	689.4	0.3	6.9	1.5	19.7	89.6	49.9	1.2	1.2	7.0	60.1	1.4	5.9	2.8	27.6	18.2
FECH		ENSG00000066926	Ferrochelatase	P22830	18	57544377-57586702	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Lyase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"Distal tubular cells: 156.5;Erythroid cells: 479.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HMC-1: 32.7;K-562: 31.4;U-266/70: 33.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA044100, HPA048177"	Approved					NA	NA			"Cluster 22: NK-cells - Unknown function"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"			"HPA044100: AB_2678809, HPA048177: AB_2680300"	"unprognostic (2.30e-1)"	"unprognostic (3.17e-2)"	"unprognostic (4.59e-3)"	"unprognostic (6.85e-2)"	"unprognostic (7.60e-2)"	"unprognostic (1.08e-1)"	"unprognostic (3.86e-2)"	"unprognostic (3.34e-2)"	"unprognostic (2.85e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.92e-1)"	"unprognostic (2.36e-1)"	"prognostic favorable (2.38e-10)"	"unprognostic (1.10e-1)"	"unprognostic (8.30e-2)"	"unprognostic (4.05e-3)"	"unprognostic (3.58e-2)"	9.3	14.7	5.2	1.9	6.3	39.6	8.8	4.7	6.3	7.8	5.8	10.0	1.8	9.2	2.9	12.0	7.6	2.6	17.0	4.8	5.2	20.9	22.0	6.5	1.9	6.3	5.3	8.4	9.2	4.3	8.9	3.2	7.2	9.5	2.4	3.6	9.0	2.4	32.2	8.4	7.2	2.8	5.3	10.0	8.4	4.7	5.3	5.0	9.7	7.4	1.8	9.9	8.5	9.7	5.3	15.1	4.3	8.2	2.6	7.4	4.2	4.5	3.4	2.9	4.0	7.3	3.0	4.8	4.3	6.8	3.9	3.5	4.2	3.8	3.7	6.6	19.0	29.5	12.8	10.5	4.9	17.7	32.7	5.4	4.0	4.0	1.4	4.2	5.3	8.0	31.4	10.9	2.1	10.1	7.8	3.8	4.3	1.9	8.7	6.3	19.7	4.7	8.6	19.1	2.5	8.4	4.8	7.4	3.4	2.5	4.6	2.8	6.8	3.3	1.9	1.4	3.2	33.4	12.4	6.3	3.5	5.6	3.9	3.7	3.8	8.1	4.5	5.0	3.2	2.4	3.0	4.9	6.6	1.0	2.8	3.3	0.6	6.9	5.2	4.3	3.2	3.8	5.2	6.3	4.7	6.3	4.8	5.2	6.3	5.3	7.2	5.3	5.3	9.7	4.9	6.4	10.6	10.4	5.6	2.5	6.7	8.6	5.2	3.8	7.8	6.1	24.5	15.7	7.2	5.5	4.2	36.6	15.4	6.7	156.5	16.4	0.4	6.6	7.9	7.3	2.4	479.7	20.3	16.3	16.5	10.3	4.6	9.7	16.5	11.8	4.2	26.3	33.4	8.4	14.6	4.1	8.2	10.6	4.9	1.1	9.9	12.7	1.8	12.2	15.4	15.1	9.2	12.1	45.5	12.4	6.4	7.2	12.5	6.5	7.0	18.2	9.8	4.1	0.0	9.0	6.8	4.1	5.5	14.2	3.1	24.2	8.1	19.1	5.7	5.0
FTH1	"FHC, FTH, FTHL6, PIG15, PLIF"	ENSG00000167996	"Ferritin heavy chain 1"	P02794	11	61959718-61967634	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Iron storage"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 49889.9;monocytes: 34409.9;Proximal enterocytes: 28837.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 23933.9;HHSteC: 24849.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB008623	Approved					NA	NA		5600000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 3: Monocytes - Immune response regulation"			"CAB008623: "	"unprognostic (7.15e-2)"	"unprognostic (1.52e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.00e-2)"	"unprognostic (2.53e-1)"	"prognostic unfavorable (7.56e-5)"	"prognostic unfavorable (6.18e-4)"	"unprognostic (3.08e-2)"	"unprognostic (2.48e-2)"	"unprognostic (6.65e-2)"	"unprognostic (2.44e-2)"	"unprognostic (8.13e-2)"	"prognostic unfavorable (5.20e-5)"	"unprognostic (2.99e-1)"	"unprognostic (4.89e-2)"	"unprognostic (3.44e-1)"	"unprognostic (5.83e-2)"	6767.7	5191.4	5741.8	3546.9	5464.0	4734.2	5696.1	5591.9	7973.3	3973.1	4801.2	4701.2	1819.9	3712.8	2421.8	4025.0	3195.6	1995.6	4779.5	5252.8	5737.2	6092.3	3500.8	6057.7	1460.4	6416.7	5812.4	3069.9	3883.8	1696.4	2105.4	1800.3	6188.9	2778.8	3357.4	3123.7	3533.1	1514.8	4695.5	2125.0	4331.6	2040.7	6506.2	3496.3	4044.1	769.5	6153.5	1109.8	3167.6	2766.8	1291.2	4718.0	3163.8	6630.2	3029.8	8290.2	1236.6	3293.8	23933.9	11490.1	6794.4	2684.1	11547.3	2694.6	2698.6	1011.0	4065.8	345.3	16669.6	7830.0	10259.7	5035.8	1118.8	2235.9	1733.9	1439.0	542.9	1720.3	10802.1	6692.1	24849.2	821.6	2626.6	15711.1	10758.7	5384.0	10038.1	8476.6	3427.6	1970.7	2622.1	3874.4	9546.5	4080.7	935.3	1361.8	2114.6	10461.4	13675.6	914.9	1508.5	2502.3	13877.6	8068.8	1044.8	1325.0	9113.3	1005.9	4645.6	4045.3	1790.3	1098.4	3791.5	8310.7	1978.7	3727.4	1732.0	662.7	2516.5	1088.1	11353.7	363.1	2030.4	29466.0	19068.5	15453.6	2306.3	22407.8	2274.9	4088.8	3267.1	2296.9	9762.5	4113.3	2710.5	2108.2	45110.1	1981.1	27515.2	7217.1	4321.5	22214.4	5741.8	5464.0	5591.9	7973.3	5252.8	5737.2	6416.7	5812.4	6188.9	6506.2	6153.5	6630.2	3864.7	1317.3	2890.3	319.3	3200.9	5157.7	7723.2	23426.3	3495.0	881.7	9884.9	10192.4	11.7	4466.7	11711.1	1918.2	573.4	4541.1	4513.5	13653.9	10888.0	10748.7	274.2	4921.8	2908.5	4303.3	2520.6	6318.6	252.8	11073.9	6803.9	5931.3	2059.7	8005.0	6736.0	1798.6	3266.1	5199.9	18411.3	738.6	153.7	3927.4	10379.8	13784.1	49889.9	527.7	4666.1	22792.0	7116.5	183.6	34409.9	12189.1	1699.3	153.3	1031.0	7813.2	7936.8	3818.1	1789.1	12995.8	28837.7	21355.6	5978.6	3311.6	2084.0	2686.9	6139.1	585.4	927.1	1983.6	3555.6	4622.6	5225.4	2496.8	4921.7	18650.3
FTMT	MtF	ENSG00000181867	"Ferritin mitochondrial"	Q8N4E7	5	121851882-121852833	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Iron storage"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	542	"testis: 54.1"	"Cell type enriched"	"Detected in some"	6	"Early spermatids: 761.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"									NA	NA				"Cluster 36: Testis - Spermatogenesis"		"Cluster 23: Spermatids - Flagellum & Golgi organization"																		"unprognostic (4.39e-2)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	54.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	761.5	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	123.2	5.6	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.4	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	27.0	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1
FXN	"CyaY, FA, FARR, FRDA, X25"	ENSG00000165060	Frataxin	Q16595	9	69035751-69079076	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Hepatocytes: 69.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB022164, HPA068304"	Supported		Supported	Mitochondria,Cytosol		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 55: Plasma cells - Humoral immune response"	Mitochondria	Cytosol	"CAB022164: , HPA068304: AB_2685970"	"unprognostic (3.38e-2)"	"unprognostic (1.54e-1)"	"unprognostic (7.47e-2)"	"unprognostic (2.37e-3)"	"unprognostic (4.08e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.99e-1)"	"unprognostic (4.19e-2)"	"unprognostic (2.53e-1)"	"unprognostic (2.71e-3)"	"unprognostic (1.10e-1)"	"unprognostic (9.06e-2)"	"unprognostic (1.67e-1)"	"unprognostic (4.74e-2)"	10.3	20.1	8.9	7.8	9.2	29.1	10.1	9.7	8.9	9.3	11.7	10.4	7.4	12.1	12.1	9.5	10.2	5.3	27.0	9.0	10.4	12.9	46.3	7.1	9.8	9.8	10.2	17.6	15.1	22.2	8.1	9.1	9.8	10.2	12.3	4.1	11.7	13.6	25.5	5.2	7.7	13.3	9.5	12.6	10.1	10.7	9.9	5.4	10.4	19.8	10.4	12.3	7.9	10.4	27.0	22.1	34.2	17.0	15.7	23.1	34.3	18.6	16.3	28.0	21.2	11.8	16.6	45.9	14.0	19.5	28.8	28.6	41.8	42.6	34.9	53.9	47.5	66.2	14.1	87.2	26.7	48.7	27.7	25.7	33.7	27.8	29.9	9.6	37.7	28.0	50.3	43.9	26.1	25.6	14.0	21.0	47.5	53.1	42.8	32.7	24.0	32.0	32.2	21.5	26.9	12.1	19.2	12.5	20.7	24.3	14.1	14.4	22.7	18.0	32.0	24.1	27.6	11.6	11.4	27.8	8.5	39.7	18.5	8.1	39.9	0.4	48.6	45.4	37.5	36.3	48.0	48.4	42.8	22.7	61.6	59.8	1.9	60.8	36.2	33.2	43.3	49.5	8.9	9.2	9.7	8.9	9.0	10.4	9.8	10.2	9.8	9.5	9.9	10.4	11.0	3.2	11.5	13.1	19.9	9.7	19.8	36.6	14.8	6.8	16.9	20.8	38.2	10.0	10.5	14.7	4.2	39.9	14.9	4.9	21.5	17.5	2.4	11.7	22.5	16.9	7.2	56.1	14.2	14.7	22.3	14.7	14.3	8.7	7.0	15.4	11.0	69.0	33.4	0.0	18.6	15.3	18.3	22.1	16.1	6.3	15.8	13.9	17.8	9.4	18.3	7.6	28.8	6.6	10.8	15.0	3.7	13.2	42.0	17.1	5.8	27.2	7.4	1.6	13.1	10.1	19.8	5.1	32.3	29.8	8.1	14.6	17.1	27.9	17.5	14.1
HCCS	"CCHL, MLS"	ENSG00000004961	"Holocytochrome c synthase"	P53701	X	11111301-11123086	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		Lyase	"Disease variant, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002946	Approved		Enhanced	Mitochondria	"Intracellular and membrane"	NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 18: U-2197 - ECM organization"	"Cluster 22: Epithelial cell types - Mixed function"	Mitochondria		"HPA002946: AB_1079041"	"prognostic unfavorable (8.69e-5)"	"unprognostic (6.89e-3)"	"unprognostic (8.46e-3)"	"unprognostic (4.92e-2)"	"unprognostic (1.34e-1)"	"unprognostic (5.44e-2)"	"prognostic unfavorable (1.35e-5)"	"unprognostic (9.18e-2)"	"unprognostic (2.73e-1)"	"unprognostic (2.52e-2)"	"unprognostic (2.10e-2)"	"unprognostic (1.60e-1)"	"prognostic favorable (6.17e-8)"	"unprognostic (2.66e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.93e-2)"	13.9	16.1	6.2	13.7	6.7	20.5	12.6	7.0	8.4	8.4	8.4	21.6	23.1	9.6	7.6	19.3	8.5	10.8	39.0	7.4	6.8	17.6	22.9	11.5	15.6	6.7	6.2	8.3	9.9	25.1	8.3	13.1	6.4	9.5	21.6	13.5	15.2	10.0	64.4	17.6	20.2	12.5	6.2	14.5	15.3	10.2	6.7	13.0	10.8	57.0	17.1	22.3	11.6	6.1	54.3	60.5	31.8	28.5	25.6	25.2	29.2	52.0	43.0	67.8	57.5	70.7	38.5	34.3	26.3	46.1	80.8	49.8	63.2	51.8	70.5	30.8	48.0	34.1	80.8	38.6	47.3	40.9	39.4	24.2	37.4	67.9	46.5	37.9	49.1	26.1	63.1	41.1	46.3	72.5	28.0	31.4	51.5	36.6	70.1	27.3	59.9	65.4	44.0	44.8	20.9	24.2	54.8	58.7	38.2	66.7	45.6	27.1	48.7	42.4	23.6	110.4	47.0	26.9	29.0	47.8	35.5	28.8	42.7	25.6	47.8	30.1	20.2	66.4	19.0	39.0	19.6	18.2	62.2	34.7	17.1	22.1	13.1	19.1	57.4	56.2	23.5	19.0	6.2	6.7	7.0	8.4	7.4	6.8	6.7	6.2	6.4	6.2	6.7	6.1	15.5	6.4	4.8	2.3	20.8	54.8	53.2	57.0	22.8	5.3	16.1	13.7	49.3	17.2	33.3	16.5	0.0	32.9	12.4	44.6	50.9	34.9	13.7	19.0	10.4	21.0	10.8	32.8	3.8	29.3	37.9	17.1	12.8	16.7	13.3	10.4	15.7	18.5	41.8	8.4	4.5	19.2	67.1	21.0	44.1	2.3	13.4	23.5	24.9	1.9	27.9	13.0	7.2	2.0	2.7	68.4	31.9	10.5	18.4	63.5	46.4	36.0	28.9	7.1	6.6	12.5	20.1	24.4	28.4	21.8	46.0	40.9	12.0	15.6	30.2	88.6
HMBS	"PBGD, PORC, UPS"	ENSG00000256269	"Hydroxymethylbilane synthase"	P08397	11	119084866-119093549	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Transferase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	6	"bone marrow: 170.8"	"Cell type enriched"	"Detected in many"	15	"Erythroid cells: 935.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006114, HPA050659"	Supported		Approved	"Lipid droplets"		NA	NA		21000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"	"Lipid droplets"		"HPA006114: AB_1079067, HPA050659: AB_2681206"	"unprognostic (6.24e-2)"	"unprognostic (9.10e-3)"	"unprognostic (1.42e-2)"	"unprognostic (4.98e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.30e-1)"	"unprognostic (2.29e-3)"	"unprognostic (2.81e-1)"	"unprognostic (2.18e-1)"	"unprognostic (1.13e-2)"	"unprognostic (6.83e-2)"	"unprognostic (5.06e-2)"	"unprognostic (2.90e-3)"	"unprognostic (3.91e-3)"	"unprognostic (9.53e-2)"	"unprognostic (1.32e-1)"	"unprognostic (6.11e-2)"	10.3	15.9	9.3	9.3	10.4	170.8	9.4	11.5	10.4	7.9	10.1	13.7	12.5	10.2	11.9	14.4	7.7	4.0	17.3	9.1	10.0	12.3	22.8	8.8	9.2	10.7	10.2	3.8	16.2	9.2	8.5	10.6	10.6	8.6	14.9	5.9	9.9	8.6	30.4	10.5	10.1	10.5	10.4	15.2	11.7	5.7	10.7	7.6	8.9	23.9	11.9	9.6	8.0	12.6	40.0	59.9	27.7	47.5	21.6	27.2	41.7	31.1	34.8	45.0	38.2	74.4	60.2	59.4	68.3	40.1	42.0	53.7	41.6	60.1	28.2	42.0	42.4	97.2	22.5	55.0	40.8	37.6	31.2	29.8	38.0	71.5	53.1	18.7	21.5	55.9	154.6	25.7	35.9	158.4	36.3	72.6	32.1	72.8	36.5	41.9	27.8	59.5	45.3	36.2	31.1	41.4	24.6	38.4	29.3	19.3	64.7	52.3	20.0	33.0	25.5	32.9	36.0	14.2	16.7	36.6	22.7	47.4	40.0	48.5	38.5	4.4	13.6	35.2	17.8	21.4	12.5	15.1	52.8	24.4	19.7	14.7	1.3	11.5	22.2	35.1	14.2	26.6	9.3	10.4	11.5	10.4	9.1	10.0	10.7	10.2	10.6	10.4	10.7	12.6	5.2	9.6	9.0	4.2	12.1	7.9	11.0	26.7	13.6	5.6	14.5	16.8	13.7	18.6	12.8	11.0	27.1	57.8	12.1	12.4	19.6	25.6	1.7	5.8	10.4	6.2	13.2	935.9	3.8	31.2	61.1	9.0	5.6	5.8	2.5	6.3	4.6	23.7	29.1	10.1	5.7	19.1	14.2	13.0	10.4	3.0	5.9	9.5	14.2	1.9	15.3	7.5	8.2	4.5	8.6	23.3	13.0	8.6	25.0	14.5	9.2	24.5	13.6	25.9	0.0	8.6	11.7	1.7	32.0	18.8	8.1	23.3	6.1	16.7	31.0	10.5
HMOX1	"bK286B10, HO-1"	ENSG00000100292	"Heme oxygenase 1"	P09601	22	35380361-35394214	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	Apoptosis	Oxidoreductase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in all"	4	"lymphoid tissue: 612.2"	"Cell type enhanced"	"Detected in many"		"Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2"	"Lineage enriched"	"Detected in all"	7	"monocytes: 329.2"	"Cell line enhanced"	"Detected in many"		"BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000635, CAB017444"	Enhanced		Uncertain	"Golgi apparatus,Plasma membrane"		NA	NA		170000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 4: Macrophages - Innate immune response"	"Golgi apparatus, Plasma membrane"		"CAB017444: AB_10617276, HPA000635: AB_1079089"	"unprognostic (3.12e-1)"	"unprognostic (1.00e-1)"	"unprognostic (9.42e-2)"	"unprognostic (6.94e-2)"	"unprognostic (5.57e-2)"	"unprognostic (2.47e-2)"	"prognostic unfavorable (1.59e-4)"	"unprognostic (7.56e-2)"	"unprognostic (1.71e-1)"	"unprognostic (4.91e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.76e-1)"	"unprognostic (1.95e-3)"	"unprognostic (1.91e-1)"	"unprognostic (4.82e-2)"	"unprognostic (2.26e-1)"	"unprognostic (7.54e-2)"	150.2	48.9	40.9	64.6	48.8	99.3	20.6	42.4	66.3	28.2	46.4	35.2	106.0	10.4	7.6	48.4	40.7	52.6	18.2	40.6	46.6	96.2	136.5	113.6	57.2	52.3	46.5	139.0	41.7	7.4	9.6	72.2	56.3	6.7	31.1	1.7	15.1	4.0	107.1	74.1	64.5	38.7	45.9	612.2	19.9	17.8	60.7	25.1	11.3	21.4	49.4	46.2	29.2	56.2	12.2	179.1	1.8	37.7	170.9	49.6	869.1	83.2	57.6	42.9	48.6	82.1	11.3	0.1	18.3	83.3	631.2	10.1	11.4	1.9	16.1	308.6	9.2	4.3	51.5	179.3	218.9	11.5	54.8	146.3	4.2	282.3	19.7	74.6	130.9	0.5	0.0	87.4	152.5	6.9	0.2	4.3	18.1	130.4	20.7	1.2	15.6	28.4	35.2	104.5	2.7	2.4	215.8	19.1	15.5	92.5	8.9	3.0	44.3	506.2	22.1	82.5	82.5	53.5	77.0	9.3	489.4	5.7	8.6	11.3	98.8	7.7	1.1	238.8	0.4	24.8	0.7	1.7	44.6	2.9	0.1	0.5	47.1	5.3	329.2	1.1	1.8	70.9	40.9	48.8	42.4	66.3	40.6	46.6	52.3	46.5	56.3	45.9	60.7	56.2	19.3	3.2	19.0	0.0	11.5	16.4	27.5	11.0	10.8	0.0	25.0	9.1	2.9	24.3	10.5	5.5	0.0	50.5	3.5	59.1	21.5	13.6	2.1	39.6	12.9	327.1	16.0	5.7	0.2	1.5	285.2	64.1	9.2	74.6	11.4	98.4	23.6	23.6	494.9	0.0	0.4	8.3	18.3	954.1	175.8	4.1	31.1	271.5	35.6	1.9	184.7	0.4	9.2	0.5	1.4	8.3	26.1	5.3	2.5	110.6	61.5	157.9	7.1	0.6	0.0	40.8	52.7	0.9	4.4	5.5	15.6	502.0	6.8	6.9	6.1	118.3
HMOX2	HO-2	ENSG00000103415	"Heme oxygenase 2"	P30519	16	4474690-4510347	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"Early spermatids: 515.3;Late spermatids: 2001.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025464, HPA040611"	Supported		Approved	Vesicles,Cytosol		NA	NA		12000	"Cluster 20: T-cells - T-cell receptor"	"Cluster 43: Testis - Unknown function"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 31: Spermatids - Spermatogenesis"	"Vesicles, Cytosol"		"CAB025464: , HPA040611: AB_10961034"	"unprognostic (3.33e-1)"	"unprognostic (3.58e-2)"	"unprognostic (1.11e-1)"	"prognostic favorable (7.91e-4)"	"unprognostic (2.74e-1)"	"unprognostic (4.27e-2)"	"unprognostic (6.23e-2)"	"unprognostic (5.77e-2)"	"unprognostic (1.43e-2)"	"unprognostic (3.60e-1)"	"unprognostic (7.74e-3)"	"unprognostic (9.87e-2)"	"prognostic favorable (8.98e-6)"	"unprognostic (3.51e-2)"	"unprognostic (4.14e-2)"	"unprognostic (1.65e-2)"	"unprognostic (2.64e-1)"	63.0	51.3	43.7	23.2	51.9	18.3	55.7	56.9	55.2	47.1	36.2	41.0	34.8	35.8	22.5	84.5	35.9	26.9	149.9	47.7	50.0	71.2	109.5	46.6	33.2	55.8	49.2	25.6	39.7	38.6	43.8	17.9	57.1	34.5	25.1	22.5	44.1	14.1	37.9	44.4	42.6	22.7	44.7	67.8	100.2	152.2	54.3	24.3	41.9	32.3	36.3	33.2	49.0	53.5	82.9	38.2	20.5	45.6	65.8	31.5	33.8	53.9	26.5	48.3	43.7	48.3	55.5	36.9	64.0	55.7	34.6	51.5	75.4	126.9	48.4	51.5	48.4	27.5	35.2	63.3	43.7	56.8	44.4	48.7	41.7	55.7	37.6	37.9	83.7	46.9	44.7	18.1	44.5	114.3	48.7	58.4	34.2	81.1	35.7	54.3	33.7	84.4	72.3	51.8	34.4	19.4	43.1	95.1	66.4	33.9	58.2	36.3	91.7	25.7	39.9	120.3	30.1	24.3	30.0	78.0	16.5	52.5	35.2	87.6	37.1	252.6	166.3	46.5	142.1	69.8	153.8	168.5	73.6	66.8	145.5	151.6	125.1	99.0	35.7	39.2	155.4	142.3	43.7	51.9	56.9	55.2	47.7	50.0	55.8	49.2	57.1	44.7	54.3	53.5	33.8	35.3	41.5	7.8	37.2	54.8	35.7	73.5	19.4	29.3	26.4	29.1	70.6	32.9	54.5	36.8	20.9	75.3	59.8	70.7	129.1	79.7	515.3	38.6	30.9	53.4	31.8	14.3	23.0	90.7	69.6	39.4	89.7	53.3	19.7	38.8	75.0	93.0	67.2	28.6	21.6	37.6	85.5	23.9	52.9	2001.6	45.4	30.6	62.2	5.6	29.3	53.9	141.1	9.5	32.9	114.9	70.7	56.1	47.1	37.7	110.8	239.3	39.9	27.8	72.3	14.6	58.0	199.7	149.8	28.2	51.6	38.4	88.3	47.4	48.9	28.7
HPS3	"BLOC2S1, SUTAL"	ENSG00000163755	"HPS3 biogenesis of lysosomal organelles complex 2 subunit 1"	Q969F9	3	149129638-149173732	"Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"			"Albinism, Disease variant, Hermansky-Pudlak syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"GAMG: 115.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA046281, HPA052778"	Approved		Approved	"Golgi apparatus,Plasma membrane"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 57: B-cells - Immune response"	"Golgi apparatus, Plasma membrane"		"HPA046281: AB_10961641, HPA052778: AB_2681943"	"unprognostic (1.47e-2)"	"unprognostic (7.83e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.11e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.50e-1)"	"prognostic unfavorable (6.04e-4)"	"unprognostic (1.33e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.82e-2)"	"unprognostic (1.08e-1)"	"prognostic unfavorable (4.38e-4)"	"unprognostic (2.00e-1)"	"unprognostic (1.28e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.06e-2)"	7.6	9.2	4.2	11.4	4.7	5.6	7.9	4.8	4.2	7.5	8.3	7.5	11.0	9.9	4.9	5.6	8.6	9.0	5.0	3.7	6.0	12.0	8.0	9.7	17.6	6.7	5.6	14.0	6.7	5.7	3.7	10.6	6.8	9.3	9.1	9.6	6.6	8.5	2.8	4.7	10.8	10.3	5.6	16.0	9.2	6.9	5.2	16.8	8.8	3.9	16.4	8.4	5.2	8.5	49.1	26.5	15.7	16.3	21.4	27.4	11.7	19.7	38.4	25.3	32.4	9.1	31.8	12.4	23.8	23.7	115.3	16.5	17.4	13.4	32.4	30.6	13.9	5.8	11.8	9.9	19.1	15.7	9.1	18.0	13.5	24.4	10.0	51.6	26.2	20.2	6.5	29.4	32.5	30.3	11.3	22.1	37.7	26.3	21.1	13.4	10.3	33.7	13.9	24.1	4.7	12.4	16.8	17.7	35.9	33.4	19.2	20.5	13.2	25.2	4.5	26.0	29.0	24.0	10.0	30.6	37.7	30.1	6.3	20.7	12.5	12.1	12.0	15.2	14.5	15.4	10.9	12.9	19.5	12.2	8.4	10.9	5.7	9.8	10.3	11.0	10.7	10.9	4.2	4.7	4.8	4.2	3.7	6.0	6.7	5.6	6.8	5.6	5.2	8.5	9.9	12.8	19.5	17.6	28.6	3.7	3.9	11.5	6.8	6.7	9.1	7.4	2.5	5.7	22.9	7.3	2.1	21.0	24.3	8.0	5.9	10.7	3.0	10.6	11.6	9.9	9.0	7.4	13.3	18.1	14.6	10.8	16.8	10.4	15.2	18.0	17.5	6.9	19.8	3.3	16.5	8.8	14.2	29.3	23.8	4.8	11.5	33.1	14.2	38.4	14.4	25.1	19.6	19.1	27.3	12.9	4.9	30.1	15.4	6.8	13.6	22.8	20.7	5.2	0.0	7.4	8.4	4.4	8.4	8.7	5.3	14.1	18.9	5.4	7.5	5.1
PPOX	"PPO, VP"	ENSG00000143224	"Protoporphyrinogen oxidase"	P50336	1	161166056-161178013	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Erythroid cells: 65.9;Respiratory ciliated cells: 84.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030123	Uncertain		Approved	Vesicles,Mitochondria,Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 49: Ciliated cells - Cilium organization"	Mitochondria	"Vesicles, Cytosol"	"HPA030123: AB_10603987"	"unprognostic (1.17e-1)"	"unprognostic (4.73e-2)"	"unprognostic (9.88e-2)"	"unprognostic (2.13e-2)"	"unprognostic (3.24e-1)"	"unprognostic (1.64e-2)"	"unprognostic (9.58e-3)"	"unprognostic (1.79e-2)"	"unprognostic (9.17e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.18e-3)"	"unprognostic (7.12e-3)"	"prognostic unfavorable (9.89e-4)"	"unprognostic (6.12e-2)"	"unprognostic (2.23e-1)"	"unprognostic (3.27e-1)"	"unprognostic (1.80e-2)"	9.3	17.1	24.2	3.5	24.5	25.2	10.3	25.2	38.2	14.5	24.7	12.7	3.9	10.9	8.3	8.9	22.0	4.7	13.1	24.4	24.7	15.5	11.5	8.6	5.7	25.0	25.0	13.8	10.8	7.2	13.7	6.5	24.6	13.4	3.9	12.6	8.7	7.7	7.6	11.2	8.5	6.6	25.0	13.6	10.9	6.9	24.0	5.0	11.9	5.6	5.2	11.6	9.6	25.4	10.0	8.0	12.7	8.5	10.4	9.3	3.5	5.9	5.7	7.5	10.3	10.4	9.3	7.4	14.3	5.3	4.1	6.3	9.8	8.8	7.1	4.6	20.3	9.0	18.9	23.9	8.6	3.0	4.6	7.6	11.0	6.3	9.4	9.4	14.7	7.0	22.8	11.2	5.6	9.2	12.0	8.6	8.2	11.2	18.8	13.6	8.2	16.7	15.1	4.2	9.8	14.7	6.6	10.3	12.0	14.6	19.9	9.5	5.7	6.5	7.1	6.5	7.5	19.4	15.3	10.5	6.8	6.0	4.9	6.3	7.2	5.3	10.4	7.6	7.2	9.0	7.8	7.6	10.4	8.2	6.8	6.9	2.9	12.0	5.2	6.6	16.1	7.8	24.2	24.5	25.2	38.2	24.4	24.7	25.0	25.0	24.6	25.0	24.0	25.4	10.9	3.2	13.7	10.4	9.8	12.0	8.3	16.6	9.1	18.0	12.1	14.1	10.1	4.3	15.6	7.3	22.9	21.4	10.6	3.6	21.5	9.5	9.8	39.1	5.9	8.3	6.0	65.9	5.9	5.6	9.4	9.1	5.1	4.6	6.3	12.3	8.9	6.1	9.3	15.2	7.5	7.3	26.4	4.7	8.4	12.1	10.2	8.0	1.8	5.6	8.1	10.4	8.2	9.0	8.9	6.3	3.8	6.8	16.9	3.2	6.6	17.2	84.4	20.9	6.6	9.6	15.6	12.8	9.3	7.2	14.9	10.4	10.6	11.1	7.5	6.2
UROD		ENSG00000126088	"Uroporphyrinogen decarboxylase"	P06132	1	45010950-45015575	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	"Decarboxylase, Lyase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in all"	5	"Erythroid cells: 806.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"K-562: 420.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027468, HPA028668, HPA030350"	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA		2600000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"	"Nucleoplasm, Cytosol"		"HPA027468: AB_1858654, HPA028668: AB_10603458, HPA030350: AB_2673440"	"unprognostic (5.90e-2)"	"unprognostic (2.94e-2)"	"unprognostic (2.49e-1)"	"unprognostic (9.61e-2)"	"unprognostic (7.94e-2)"	"unprognostic (1.96e-1)"	"prognostic unfavorable (2.48e-4)"	"unprognostic (2.31e-2)"	"unprognostic (4.76e-2)"	"unprognostic (6.75e-2)"	"unprognostic (7.72e-3)"	"unprognostic (3.92e-1)"	"unprognostic (1.24e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.41e-1)"	"unprognostic (8.73e-2)"	"unprognostic (8.12e-2)"	51.7	120.1	72.0	25.5	73.9	199.0	48.2	72.0	79.3	40.8	77.2	49.3	29.2	46.9	54.7	34.2	49.2	30.8	70.6	73.1	74.5	58.0	100.9	34.8	35.2	72.1	73.4	51.1	45.1	115.0	42.6	39.4	73.6	35.1	30.1	24.7	61.4	44.2	75.9	31.7	30.7	54.7	72.9	37.8	38.5	44.8	73.6	44.0	54.0	83.8	36.1	40.3	32.7	73.8	66.0	42.5	67.0	89.1	113.4	107.7	31.8	87.4	209.8	163.9	125.2	59.9	32.3	46.4	82.3	122.8	116.3	31.1	127.2	153.6	116.9	42.9	133.4	245.4	95.4	200.7	132.4	79.0	42.6	115.1	97.6	154.1	132.3	121.8	208.9	92.9	420.8	48.5	157.6	53.5	49.9	62.9	104.1	51.5	145.9	76.5	96.5	69.9	141.7	54.4	73.9	57.3	89.1	63.9	134.3	73.7	50.8	77.6	137.5	96.9	71.6	34.2	130.5	49.4	60.1	38.1	141.0	117.6	47.2	72.3	111.9	65.5	57.4	81.5	58.8	84.9	69.2	56.7	149.7	81.9	63.6	58.0	20.1	87.4	50.9	102.3	88.7	122.1	72.0	73.9	72.0	79.3	73.1	74.5	72.1	73.4	73.6	72.9	73.6	73.8	25.8	44.8	38.0	7.8	25.4	22.9	35.8	101.4	43.9	27.3	31.0	37.1	74.4	41.5	45.3	27.6	16.7	98.6	22.1	21.4	90.1	73.5	8.1	20.3	30.7	42.7	18.0	806.8	9.4	63.7	54.6	57.1	17.3	21.2	52.6	20.4	38.6	98.5	101.8	13.5	6.7	20.2	73.2	37.9	29.4	16.2	79.6	38.5	48.0	5.6	103.6	89.7	24.7	7.1	7.3	51.2	23.7	56.1	36.8	15.9	32.7	134.5	32.9	25.3	39.5	29.4	75.0	37.3	42.3	31.6	24.7	49.8	23.3	72.7	20.9	29.1
UROS		ENSG00000188690	"Uroporphyrinogen III synthase"	P10746	10	125784980-125823258	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Heme biosynthesis, Porphyrin biosynthesis"	Lyase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Erythroid cells: 231.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044038	Approved		Approved	Nucleoplasm,Cytosol		NA	NA		69000	"Cluster 24: B-cells - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 36: HEL - Hemostasis"	"Cluster 6: Erythroid cells - Oxygen transport"	Nucleoplasm	Cytosol	"HPA044038: AB_10966692"	"unprognostic (8.86e-2)"	"unprognostic (7.64e-2)"	"unprognostic (2.77e-1)"	"unprognostic (7.19e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.41e-1)"	"unprognostic (1.08e-1)"	"unprognostic (5.82e-2)"	"unprognostic (1.27e-1)"	"unprognostic (4.35e-3)"	"unprognostic (4.23e-3)"	"unprognostic (2.00e-2)"	"prognostic unfavorable (6.27e-4)"	"unprognostic (1.58e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.68e-1)"	"unprognostic (3.93e-1)"	27.9	41.3	54.1	13.4	55.3	67.5	26.9	40.6	64.5	15.9	33.0	29.9	20.9	21.4	56.9	24.9	19.3	15.6	73.2	56.3	45.8	40.7	59.7	20.5	18.8	41.6	48.1	22.5	32.9	30.0	29.9	11.3	43.5	27.4	16.5	26.2	29.6	19.1	83.8	23.0	24.2	18.1	40.2	28.0	29.6	31.2	51.8	18.6	32.5	80.0	19.1	27.3	17.0	47.8	45.5	56.3	29.8	74.9	38.5	42.2	51.9	51.4	94.5	39.0	34.6	22.9	54.0	58.4	24.7	72.9	24.3	23.5	18.5	43.1	31.3	78.1	39.9	125.3	27.9	40.1	67.3	50.7	29.7	59.3	20.7	25.8	66.0	47.5	34.4	48.5	24.4	54.1	63.5	65.2	51.2	72.8	37.7	31.8	54.0	33.1	34.1	37.3	53.9	28.2	26.2	46.8	51.6	41.8	80.7	30.8	40.4	59.1	33.8	52.3	19.6	38.1	48.2	50.7	36.8	40.6	75.6	23.1	26.3	4.9	31.9	4.6	30.1	33.1	33.9	30.1	29.3	38.6	53.5	37.5	38.1	29.6	2.1	53.6	31.9	25.3	29.8	38.1	54.1	55.3	40.6	64.5	56.3	45.8	41.6	48.1	43.5	40.2	51.8	47.8	19.0	19.2	23.1	20.5	34.3	9.3	12.0	31.8	9.6	49.3	36.2	39.5	70.5	40.0	28.6	36.8	45.9	60.8	36.3	19.1	101.8	59.7	57.0	11.2	25.5	22.2	14.5	231.5	23.9	59.6	47.4	33.3	23.9	16.9	11.4	112.3	28.2	53.4	79.3	47.1	25.2	25.6	40.7	47.8	20.8	123.7	35.8	31.6	62.2	9.4	58.7	77.0	69.0	13.6	29.6	42.7	15.8	40.6	46.9	27.3	52.9	142.6	20.4	42.3	6.6	22.8	36.7	55.7	100.9	28.5	12.8	20.0	37.8	55.0	38.8	21.3