Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ACAD8		ENSG00000151498	"Acyl-CoA dehydrogenase family member 8"	Q9UKU7	11	134253548-134265855	"Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Branched-chain amino acid catabolism, Transcription, Transcription regulation"	"Activator, Oxidoreductase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 59.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA040689, HPA043903"	Enhanced					NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 21: OE19 - Mitochondria"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA040689: AB_2677080, HPA043903: AB_2678724"	"unprognostic (5.00e-2)"	"unprognostic (2.40e-2)"	"prognostic favorable (7.62e-4)"	"unprognostic (7.57e-3)"	"unprognostic (9.83e-2)"	"prognostic favorable (6.19e-4)"	"unprognostic (2.53e-1)"	"prognostic favorable (2.38e-4)"	"unprognostic (4.10e-2)"	"unprognostic (2.84e-1)"	"unprognostic (7.81e-3)"	"unprognostic (2.16e-1)"	"prognostic favorable (6.42e-10)"	"unprognostic (1.08e-1)"	"unprognostic (1.17e-2)"	"unprognostic (4.02e-2)"	"unprognostic (1.03e-2)"	11.0	18.1	13.9	3.5	14.2	6.8	11.3	14.3	15.4	7.5	18.7	11.6	11.3	6.3	12.6	9.6	9.4	5.2	27.2	14.7	14.3	31.6	24.8	7.8	5.0	14.3	14.1	6.9	16.7	12.4	6.5	4.8	13.8	20.5	10.9	5.0	12.6	7.5	32.5	14.3	8.4	8.3	14.5	8.6	12.6	6.3	14.8	8.5	27.7	39.2	8.9	8.4	6.9	14.8	5.9	5.9	11.8	17.6	20.2	11.5	13.5	11.3	14.0	14.7	10.3	16.2	10.8	14.2	21.1	11.7	15.5	6.0	14.6	14.3	10.2	13.0	4.7	29.4	5.8	11.3	17.0	16.5	18.3	13.8	4.4	14.8	4.5	13.3	16.3	20.8	13.8	7.0	12.4	7.5	12.2	18.1	17.0	49.8	9.7	9.8	11.9	8.5	20.1	17.5	3.7	11.7	19.5	14.8	7.3	11.9	31.0	15.0	11.3	7.1	7.5	6.2	11.2	7.8	3.8	12.7	7.2	15.4	11.2	36.2	13.4	23.1	11.8	13.5	11.5	11.6	11.1	11.7	12.7	9.2	13.0	11.7	12.1	31.5	12.9	10.8	15.1	12.3	13.9	14.2	14.3	15.4	14.7	14.3	14.3	14.1	13.8	14.5	14.8	14.8	11.7	3.2	12.2	15.3	8.8	6.0	4.7	23.5	7.4	11.2	17.5	11.9	24.6	4.3	19.7	18.4	14.6	19.7	14.0	20.0	52.8	12.1	5.3	8.2	11.8	9.7	3.6	12.0	21.5	11.9	10.6	9.8	10.2	8.5	3.8	15.7	10.8	36.7	12.9	15.2	16.0	14.3	48.8	14.2	6.9	6.1	11.5	10.0	28.4	13.1	12.7	11.8	9.2	12.1	15.8	12.6	15.8	10.1	14.6	5.9	17.4	59.8	20.1	17.1	6.6	8.7	9.6	22.4	17.3	10.9	7.7	8.3	10.5	36.0	14.9	5.3
ACAD9	"MGC14452, NPD002"	ENSG00000177646	"Acyl-CoA dehydrogenase family member 9"	Q9H845	3	128879596-128924003	"Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037716, HPA046720"	Supported		Enhanced	Mitochondria		No	No			"Cluster 14: Monocytes - Unknown function"	"Cluster 59: Non-specific - Translation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"HPA037716: AB_10673638, HPA046720: AB_2679773"	"unprognostic (1.04e-1)"	"unprognostic (1.28e-2)"	"unprognostic (1.15e-1)"	"prognostic unfavorable (3.05e-4)"	"unprognostic (3.61e-1)"	"unprognostic (2.83e-1)"	"prognostic unfavorable (3.67e-6)"	"unprognostic (1.30e-1)"	"unprognostic (3.74e-1)"	"unprognostic (3.25e-2)"	"unprognostic (1.37e-1)"	"unprognostic (6.96e-3)"	"prognostic favorable (4.32e-8)"	"unprognostic (1.52e-1)"	"unprognostic (2.64e-2)"	"unprognostic (6.56e-2)"	"unprognostic (9.96e-2)"	16.7	20.5	9.0	6.1	8.5	4.7	14.5	9.6	10.2	14.4	9.1	13.6	9.0	14.6	7.7	23.2	12.9	7.3	21.9	8.3	8.7	15.6	20.6	11.0	6.6	8.2	8.7	12.9	14.4	27.7	14.6	8.4	8.4	12.1	9.4	4.1	14.2	12.0	30.4	48.0	11.2	11.1	7.4	12.2	15.9	12.5	8.7	12.1	13.6	28.7	11.2	12.9	14.5	9.0	46.2	22.6	18.0	12.6	28.7	20.7	17.5	22.4	26.2	43.6	36.8	33.3	27.1	33.3	21.1	29.5	29.0	35.5	33.8	45.9	32.8	21.2	23.1	29.3	46.8	24.4	21.6	23.9	10.6	22.5	16.8	23.6	26.7	25.1	35.8	25.2	14.4	11.4	29.5	46.5	36.7	19.0	9.9	49.3	33.8	25.5	17.4	35.1	30.9	25.1	19.0	11.6	37.0	32.9	23.2	17.4	44.5	54.8	18.2	13.2	13.4	14.2	20.3	14.5	5.8	28.3	28.3	21.4	22.7	2.4	15.1	4.9	8.3	18.3	7.8	8.1	7.6	7.3	17.5	5.4	6.2	8.0	0.7	6.8	25.2	9.9	8.3	12.1	9.0	8.5	9.6	10.2	8.3	8.7	8.2	8.7	8.4	7.4	8.7	9.0	10.4	16.0	21.7	13.1	9.3	6.2	11.4	16.7	8.6	14.1	11.9	9.5	30.5	15.7	14.8	14.7	10.4	26.2	10.5	11.7	21.5	20.6	20.2	10.4	11.5	11.2	5.4	14.3	14.3	17.8	18.8	12.9	16.8	12.9	16.5	12.0	15.7	26.7	31.5	10.1	17.7	7.4	16.2	9.5	4.0	17.3	10.2	10.8	16.0	7.5	13.4	15.0	12.3	6.0	12.2	14.1	8.7	14.7	9.5	8.1	9.4	26.3	12.0	11.9	13.1	12.7	14.9	22.6	9.6	13.5	14.2	30.6	8.2	18.1	14.3	8.4
ACADM	"ACAD1, MCAD, MCADH"	ENSG00000117054	"Acyl-CoA dehydrogenase medium chain"	P11310	1	75724431-75787575	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 367.3;skeletal muscle: 380.0;tongue: 475.9"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Daudi: 289.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006198, HPA026542"	Enhanced		Enhanced	Mitochondria		NA	NA		930000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA006198: AB_1078087, HPA026542: AB_1844469"	"unprognostic (9.04e-3)"	"unprognostic (2.36e-1)"	"prognostic favorable (7.30e-4)"	"unprognostic (5.09e-3)"	"unprognostic (1.61e-3)"	"unprognostic (5.68e-2)"	"unprognostic (6.75e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.02e-2)"	"unprognostic (4.95e-2)"	"unprognostic (9.40e-3)"	"unprognostic (3.35e-1)"	"prognostic favorable (3.83e-8)"	"unprognostic (1.27e-1)"	"unprognostic (4.09e-2)"	"unprognostic (3.56e-2)"	"unprognostic (1.24e-1)"	81.9	82.2	25.2	24.3	25.0	17.3	69.9	26.6	42.2	29.3	30.4	46.8	103.9	20.0	25.3	51.3	30.6	27.8	217.8	24.3	25.9	295.9	367.3	22.6	42.6	26.9	26.8	35.7	35.9	66.3	19.2	16.9	25.8	26.8	49.5	21.2	31.4	26.2	380.0	14.4	75.6	25.5	26.2	27.4	52.8	35.7	25.8	29.7	38.4	475.9	44.3	32.7	21.3	25.2	25.8	20.5	61.0	26.8	53.1	42.1	17.5	48.1	40.4	46.1	38.5	38.3	39.5	289.1	40.7	34.4	39.0	22.8	54.9	41.8	57.8	113.0	25.5	94.4	58.5	58.3	36.4	80.0	23.9	50.7	23.5	39.8	22.8	35.0	36.2	56.6	102.3	60.4	50.5	9.6	96.3	40.6	50.2	80.4	49.5	118.8	83.8	30.6	77.9	70.7	33.8	43.0	38.0	111.6	102.0	43.1	32.7	107.6	20.2	29.9	29.6	26.6	78.1	38.6	62.0	128.1	25.8	67.0	35.3	15.3	14.2	19.3	17.1	20.9	27.3	40.7	17.8	21.5	21.4	24.6	20.3	23.6	0.5	25.0	20.4	23.2	19.5	19.5	25.2	25.0	26.6	42.2	24.3	25.9	26.9	26.8	25.8	26.2	25.8	25.2	42.9	57.7	58.3	29.7	56.5	27.3	41.8	69.0	44.3	39.0	49.0	40.9	373.1	52.9	63.0	58.8	25.0	35.8	39.4	42.6	344.4	37.9	55.4	27.1	32.2	36.2	40.7	67.6	51.6	26.5	19.5	47.6	26.0	25.4	44.9	61.5	43.9	261.2	75.7	30.3	46.7	38.7	63.1	45.6	22.2	24.4	46.9	38.2	51.6	19.7	32.8	53.7	29.9	36.2	36.0	21.2	49.7	45.5	74.9	24.2	88.0	564.8	106.7	30.0	0.0	38.6	43.7	76.3	86.1	46.6	27.0	15.3	39.4	72.5	46.7	35.9
ACADVL	"ACAD6, LCACD, VLCAD"	ENSG00000072778	"Acyl-CoA dehydrogenase very long chain"	P49748	17	7217125-7225266	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase	"Cardiomyopathy, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 850.4"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019006, HPA020595"	Enhanced		Supported	Nucleoplasm,Nucleoli,Mitochondria		NA	NA		98000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Mitochondria	"Nucleoplasm, Nucleoli"	"HPA019006: AB_1844478, HPA020595: AB_1844479"	"unprognostic (4.81e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.21e-2)"	"unprognostic (1.09e-2)"	"unprognostic (6.63e-3)"	"unprognostic (1.51e-1)"	"unprognostic (1.89e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.21e-1)"	"prognostic favorable (6.87e-4)"	"unprognostic (3.55e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.58e-1)"	"unprognostic (4.01e-1)"	"unprognostic (2.84e-3)"	197.9	405.2	120.1	78.7	131.0	103.5	142.9	128.4	126.7	110.5	170.6	157.3	306.2	98.5	44.4	181.0	94.0	92.6	576.8	117.8	125.0	215.3	517.4	106.7	52.0	127.5	125.3	80.9	236.5	159.6	189.6	112.0	124.8	133.2	131.6	34.9	158.5	113.9	850.4	135.7	270.6	110.6	118.2	132.2	186.4	75.9	132.0	83.4	159.3	817.1	82.9	137.1	115.3	122.7	193.7	162.5	65.8	92.4	271.2	99.2	135.9	156.5	169.0	136.9	84.5	67.2	155.3	90.4	109.0	260.0	49.7	147.9	43.8	135.5	119.6	295.9	47.1	50.6	120.9	101.1	131.2	49.0	129.5	112.5	122.0	114.7	178.5	212.6	124.8	111.3	73.3	110.2	222.7	65.3	49.6	68.4	34.3	178.4	91.9	70.4	78.3	227.2	305.1	155.0	19.1	47.3	206.8	224.8	110.8	60.6	102.8	74.9	151.5	127.5	101.6	75.9	149.9	104.5	59.1	5.2	230.7	85.7	94.9	24.2	96.1	121.3	39.1	57.8	35.7	25.2	32.5	43.8	99.9	24.6	23.7	29.1	20.2	37.8	39.3	80.4	31.8	79.4	120.1	131.0	128.4	126.7	117.8	125.0	127.5	125.3	124.8	118.2	132.0	122.7	109.9	60.9	81.9	143.3	72.3	87.3	336.0	322.4	91.6	42.0	157.7	104.5	451.4	138.7	206.7	202.3	62.6	482.9	87.7	484.2	185.9	310.8	133.0	87.2	52.7	77.4	179.3	65.2	40.9	77.0	197.8	118.6	406.7	88.5	88.4	121.1	53.6	365.4	182.4	33.7	33.4	251.8	233.9	67.9	94.6	249.9	124.5	101.5	81.8	34.7	274.9	40.7	73.2	23.1	24.5	106.1	388.9	132.8	172.3	369.0	489.8	345.8	144.1	41.3	105.2	88.3	147.4	114.3	47.8	113.8	87.5	663.3	75.5	169.2	316.8	367.5
ACOX3		ENSG00000087008	"Acyl-CoA oxidase 3, pristanoyl"	O15254	4	8366282-8440723	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Fatty acid metabolism, Lipid metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Syncytiotrophoblasts: 74.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035840, HPA035841"	Uncertain		Supported	Peroxisomes		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Peroxisomes		"HPA035840: AB_10696514, HPA035841: AB_10671940"	"unprognostic (3.07e-2)"	"unprognostic (5.51e-2)"	"unprognostic (1.12e-1)"	"prognostic favorable (2.16e-4)"	"unprognostic (5.52e-2)"	"unprognostic (1.81e-3)"	"unprognostic (2.21e-1)"	"unprognostic (3.37e-2)"	"unprognostic (2.27e-1)"	"unprognostic (4.43e-2)"	"unprognostic (4.81e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.46e-2)"	"unprognostic (3.58e-2)"	"unprognostic (2.84e-1)"	"unprognostic (1.69e-1)"	"unprognostic (2.65e-1)"	7.7	8.8	5.8	6.4	5.2	4.4	12.2	3.8	7.2	9.5	5.9	8.4	8.9	5.6	4.3	26.6	6.6	5.9	16.2	5.3	4.9	6.5	14.9	7.2	6.6	5.9	4.6	7.5	12.0	7.1	4.5	8.4	4.7	10.5	6.3	3.8	15.4	8.4	6.4	12.5	8.9	11.4	4.2	5.3	10.1	2.9	5.0	4.6	8.5	5.6	8.5	10.1	13.7	7.1	8.9	9.6	10.5	14.1	11.0	18.7	17.2	11.1	15.1	18.5	16.1	4.8	11.7	11.9	11.7	22.8	25.0	5.4	4.6	14.4	14.3	4.1	4.5	5.2	8.2	14.8	18.3	10.7	9.4	18.9	12.1	16.7	6.5	13.3	22.1	13.1	7.0	10.6	16.1	8.2	11.4	15.6	5.9	11.3	16.4	11.8	17.3	14.3	11.2	12.4	5.1	11.7	14.2	7.2	7.3	8.6	7.2	14.9	21.7	18.2	5.9	7.5	11.8	7.9	5.6	5.4	23.2	13.1	11.8	0.1	13.2	3.3	6.1	15.2	6.3	5.4	7.1	7.8	17.8	4.9	6.5	6.7	3.1	9.5	14.4	21.4	10.4	9.4	5.8	5.2	3.8	7.2	5.3	4.9	5.9	4.6	4.7	4.2	5.0	7.1	6.2	6.4	5.9	14.7	4.8	4.5	7.6	12.3	8.6	8.2	11.6	7.6	9.4	10.0	9.8	11.0	33.3	23.9	7.7	10.9	3.9	17.3	4.4	13.1	4.2	5.6	1.8	3.0	13.2	13.7	9.3	6.6	10.2	10.0	0.0	21.7	4.6	14.2	10.2	1.7	14.2	4.9	14.2	4.1	4.4	3.3	6.8	5.3	5.4	6.5	7.6	3.8	2.1	12.5	14.5	16.9	7.4	11.3	5.6	9.1	18.3	8.2	11.2	18.6	0.0	3.8	6.9	2.4	2.3	14.1	5.8	74.6	6.0	6.0	7.5	11.4
ACP2	LAP	ENSG00000134575	"Acid phosphatase 2, lysosomal"	P11117	11	47239302-47248906	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Hepatocytes: 89.3;Hofbauer cells: 113.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"intermediate monocyte: 69.9"	"Lineage enriched"	"Detected in all"	5	"monocytes: 69.9"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA		12000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 4: Macrophages - Innate immune response"				"unprognostic (5.27e-3)"	"unprognostic (1.56e-1)"	"unprognostic (3.86e-2)"	"prognostic favorable (1.04e-4)"	"unprognostic (7.90e-3)"	"unprognostic (2.93e-1)"	"unprognostic (6.16e-3)"	"unprognostic (1.09e-1)"	"unprognostic (2.63e-1)"	"unprognostic (3.28e-3)"	"unprognostic (2.64e-3)"	"unprognostic (5.42e-2)"	"unprognostic (1.07e-2)"	"unprognostic (1.79e-1)"	"unprognostic (1.20e-1)"	"unprognostic (8.68e-3)"	"unprognostic (1.57e-1)"	25.2	36.6	17.3	22.9	17.1	6.4	21.8	17.0	18.5	16.5	22.1	23.3	42.9	15.8	29.8	14.3	14.1	19.6	21.7	19.8	26.0	27.4	80.5	21.4	29.4	20.8	19.6	11.1	45.9	21.3	21.3	28.7	23.1	25.4	18.1	11.9	50.3	18.3	14.0	11.4	31.9	16.9	16.9	29.1	24.8	12.2	22.0	13.7	19.3	14.8	15.3	22.0	13.1	17.2	16.5	33.5	31.9	28.2	28.1	13.6	24.4	26.6	47.1	47.5	49.4	23.3	26.3	4.3	21.9	34.2	14.3	23.7	16.9	24.6	22.5	85.5	29.1	11.1	48.1	24.6	38.4	16.4	27.1	34.1	15.2	24.6	14.5	28.3	34.9	14.1	20.3	33.9	31.5	26.8	13.4	14.2	21.5	24.8	20.0	10.8	43.1	36.2	34.9	37.6	16.7	26.0	36.8	80.1	19.2	16.3	49.0	14.0	21.0	23.9	19.8	31.4	38.4	28.1	40.0	3.6	35.0	8.2	37.6	12.5	16.9	7.2	12.3	69.9	9.4	2.5	7.6	11.1	15.1	1.5	6.6	5.7	2.8	9.7	48.2	0.6	8.3	10.9	17.3	17.1	17.0	18.5	19.8	26.0	20.8	19.6	23.1	16.9	22.0	17.2	13.3	19.2	18.6	6.2	5.6	4.1	9.3	42.2	10.2	14.4	13.5	9.1	9.2	21.5	29.4	18.4	6.2	41.3	2.6	37.6	9.8	50.6	1.8	7.7	15.6	18.3	15.0	13.5	6.9	60.1	33.3	15.3	17.3	12.1	12.0	10.7	45.7	89.3	113.5	11.8	8.9	26.7	22.4	80.0	3.9	3.5	5.0	33.8	24.9	3.7	29.8	20.6	7.2	8.5	4.3	33.5	29.5	10.5	21.1	10.9	55.3	33.4	19.2	11.9	19.7	8.1	14.5	11.8	19.1	9.5	2.4	29.3	5.8	25.2	14.3	8.6
ACP3	"ACP-3, ACPP, PAP, TM-PAP"	ENSG00000014257	"Acid phosphatase 3"	P15309	3	132317369-132368298	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		Hydrolase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	76	"prostate: 3643.7"	"Group enriched"	"Detected in some"	5	"Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9"	"Cancer enriched"	"Detected in many"	275	"prostate cancer: 1227.2"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 139.7"	"Lineage enhanced"	"Detected in many"		"granulocytes: 139.7"	"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB000071, HPA004335, HPA063916"	Enhanced				"Secreted to blood"	NA	NA	460000	480000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 51: Non-specific - Unknown function"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 47: Cytotrophoblasts - Unknown function"			"CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152"	"unprognostic (6.67e-2)"	"unprognostic (4.70e-2)"	"unprognostic (1.76e-1)"	"unprognostic (7.77e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.58e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.41e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.78e-3)"	"unprognostic (2.14e-1)"	"unprognostic (5.95e-2)"	"unprognostic (9.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.18e-1)"	"unprognostic (3.91e-2)"	"unprognostic (1.71e-1)"	3.1	5.4	0.9	7.3	1.3	17.5	3.4	0.9	0.9	6.3	1.2	3.6	3.1	1.4	17.2	47.7	2.2	1.5	0.6	1.2	1.5	28.9	1.4	4.5	1.9	1.5	1.3	1.1	2.7	3.9	0.5	10.8	1.5	3643.7	6.5	0.4	10.6	0.8	0.2	27.0	3.4	1.8	1.0	1.8	3.2	2.4	1.0	1.0	2.4	0.2	6.5	1.8	12.1	1.7	0.5	0.1	0.0	0.0	0.2	0.9	11.7	0.3	17.7	0.1	0.0	0.4	0.4	10.6	0.8	0.0	0.1	4.8	0.0	0.1	0.0	0.1	0.5	2.0	0.4	0.2	0.2	7.3	0.1	1.1	1.6	0.1	0.0	0.2	0.0	0.0	0.1	2.7	0.2	0.1	0.0	13.5	0.7	22.3	2.1	0.1	0.0	58.0	5.0	6.5	0.0	4.1	0.1	2.0	0.6	1.7	0.3	6.5	0.0	0.1	0.1	2.5	0.1	0.8	0.4	17.2	14.9	12.7	0.2	0.1	30.2	139.7	0.2	26.9	0.2	0.7	0.0	0.0	35.3	0.0	0.0	0.0	26.4	2.6	25.8	2.4	0.0	10.1	0.9	1.3	0.9	0.9	1.2	1.5	1.5	1.3	1.5	1.0	1.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	13.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.8	1.3	0.0	0.0	0.0	0.0	0.0	0.0	4.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.9	0.0	0.0	0.0	0.0
ACP5	"HPAP, TRAP"	ENSG00000102575	"Acid phosphatase 5, tartrate resistant"	P13686	19	11574660-11579008	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lung: 174.1"	"Cell type enhanced"	"Detected in many"		"Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"memory B-cell: 200.1"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9"	"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"			"CAB002584, HPA057655, HPA059463"	Enhanced		Uncertain	Cytosol	"Intracellular and membrane"	NA	NA		4000000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 4: Macrophages - Innate immune response"	Cytosol		"CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028"	"unprognostic (4.27e-2)"	"unprognostic (2.05e-2)"	"unprognostic (2.93e-1)"	"unprognostic (8.60e-3)"	"unprognostic (2.96e-1)"	"unprognostic (1.95e-2)"	"unprognostic (5.21e-2)"	"unprognostic (5.17e-3)"	"unprognostic (5.13e-2)"	"unprognostic (3.80e-1)"	"unprognostic (3.66e-3)"	"unprognostic (9.09e-2)"	"unprognostic (1.39e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.17e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.19e-1)"	9.4	6.0	2.2	42.4	3.9	9.4	25.6	2.5	21.4	34.7	3.0	46.4	31.9	19.2	7.8	23.4	8.6	26.7	5.1	1.9	3.9	74.0	32.5	174.1	87.1	4.1	3.1	20.3	11.9	2.4	1.3	13.3	6.0	19.6	36.4	20.1	14.3	7.0	1.4	24.9	30.2	13.3	4.1	43.5	38.7	4.0	15.7	25.4	3.0	5.0	43.6	33.1	11.3	5.7	10.2	1.1	0.0	0.2	0.5	0.0	41.1	1.1	25.8	0.0	0.1	0.4	0.3	1.4	1.8	9.0	5.9	0.3	0.0	4.5	0.1	12.1	0.8	0.3	0.0	5.0	1.4	0.1	0.6	0.0	4.1	0.4	0.0	0.0	0.0	0.0	30.4	0.2	0.0	2.3	0.9	1.4	0.8	0.3	0.7	0.4	1.8	41.4	0.0	0.4	0.7	1.0	0.0	0.0	127.6	1.1	0.2	0.4	0.9	102.9	1.2	1.8	0.3	0.7	5.7	0.6	23.7	0.1	4.0	0.4	35.3	76.6	15.8	36.1	8.8	200.1	26.0	19.6	7.3	110.9	35.3	20.2	10.4	13.3	36.3	62.5	67.8	36.4	2.2	3.9	2.5	21.4	1.9	3.9	4.1	3.1	6.0	4.1	15.7	5.7	2.2	9.6	7.8	0.0	75.7	10.3	11.0	21.8	25.0	18.3	14.6	18.4	1.4	15.7	5.7	7.3	18.8	33.4	21.2	7.0	9.8	1.8	0.2	0.7	9.1	30.9	3.0	24.5	0.0	11.3	32.7	19.8	10.7	0.9	63.7	0.8	426.9	8.4	426.7	1.7	0.0	4.7	10.2	106.0	68.6	0.7	1.8	298.2	14.2	1.0	79.8	48.5	8.2	0.0	0.1	4.4	20.4	12.0	33.4	14.5	12.7	145.8	2.5	41.4	0.0	0.4	2.8	0.1	0.2	14.6	11.1	26.1	29.5	0.1	6.7	6.1
ACP6	"ACPL1, LPAP"	ENSG00000162836	"Acid phosphatase 6, lysophosphatidic"	Q9NPH0	1	147629652-147670524	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Lipid metabolism, Phospholipid metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 74.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"OE19: 108.9;RPTEC TERT1: 119.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028560	Uncertain				"Intracellular and membrane"	NA	NA		64000	"Cluster 35: T-regs - Unknown function"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 64: Astrocytes - Nervous system maintenance"			"HPA028560: AB_10602427"	"unprognostic (3.17e-2)"	"unprognostic (3.01e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.87e-2)"	"unprognostic (3.85e-1)"	"unprognostic (8.50e-3)"	"unprognostic (3.36e-3)"	"unprognostic (1.00e-1)"	"unprognostic (6.32e-2)"	"unprognostic (1.30e-2)"	"unprognostic (3.09e-1)"	"unprognostic (1.06e-1)"	"unprognostic (4.52e-2)"	"unprognostic (3.94e-1)"	"unprognostic (8.07e-2)"	"unprognostic (1.26e-1)"	"prognostic favorable (6.44e-4)"	6.3	13.6	6.2	4.2	6.3	5.0	17.8	5.6	6.6	11.8	7.9	11.4	7.4	8.3	16.2	7.8	12.7	6.8	8.4	5.9	6.3	17.5	13.2	7.3	3.9	6.3	6.9	9.3	11.0	21.9	15.2	4.2	6.2	12.6	9.7	3.6	10.4	11.2	6.7	9.3	8.8	6.0	6.0	6.0	12.4	5.7	6.1	7.9	15.2	6.0	6.9	11.2	6.7	5.7	21.1	8.5	7.1	12.7	4.5	4.3	20.2	4.8	14.8	14.8	17.5	10.2	31.9	6.1	17.4	10.4	11.4	35.6	9.6	32.0	15.4	8.2	16.1	21.9	11.8	19.4	13.2	3.9	0.8	6.3	23.3	7.7	15.4	17.6	15.2	30.2	10.5	3.4	17.0	15.8	16.5	10.0	17.0	108.9	62.9	11.7	6.1	70.9	119.7	41.3	5.8	7.1	17.5	12.5	36.5	15.9	20.3	6.0	10.7	4.6	8.6	0.9	15.1	13.4	21.3	2.8	8.7	0.3	25.8	0.1	2.3	13.4	4.6	0.8	7.9	2.6	7.5	6.1	5.4	2.8	8.2	7.0	3.5	0.3	0.3	3.4	14.8	2.7	6.2	6.3	5.6	6.6	5.9	6.3	6.3	6.9	6.2	6.0	6.1	5.7	2.1	19.2	13.9	74.4	2.9	1.1	6.1	7.4	7.4	3.1	6.3	6.3	7.0	10.0	6.7	16.5	0.0	19.7	7.0	3.7	17.6	7.5	6.0	9.1	2.3	2.4	9.1	4.2	14.2	15.3	7.2	2.4	10.7	9.4	1.3	15.2	5.3	10.9	4.6	0.0	20.6	8.5	8.2	4.8	6.7	1.5	5.9	2.9	3.6	15.0	3.4	8.8	4.1	18.1	10.4	18.7	5.4	4.1	3.8	4.9	6.3	14.4	11.9	1.1	13.1	5.7	7.7	7.5	4.7	9.1	1.3	8.1	9.6	7.3	8.5	5.8
ADA	ADA1	ENSG00000196839	"Adenosine deaminase"	P00813	20	44619522-44652233	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Cell adhesion, Nucleotide metabolism"	Hydrolase	"Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	8	"intestine: 507.2;lymphoid tissue: 259.0"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 76.4;Extravillous trophoblasts: 128.2;NK-cells: 56.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"intermediate monocyte: 168.5;NK-cell: 94.5;non-classical monocyte: 362.8;plasmacytoid DC: 218.6"	"Group enriched"	"Detected in all"	4	"dendritic cells: 218.6;monocytes: 362.8;NK-cells: 94.5"	"Group enriched"	"Detected in many"	5	"JURKAT: 570.9;MOLT-4: 1915.5"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA001399, CAB004307, HPA023884"	Enhanced		Supported	"Plasma membrane,Cytosol"		No	No		470000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 9: Intestine - Unknown function"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Plasma membrane"	Cytosol	"CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573"	"unprognostic (4.30e-2)"	"unprognostic (6.89e-2)"	"unprognostic (3.96e-2)"	"prognostic unfavorable (1.23e-7)"	"unprognostic (9.33e-2)"	"unprognostic (9.07e-3)"	"prognostic unfavorable (6.77e-5)"	"prognostic unfavorable (2.20e-4)"	"unprognostic (1.59e-1)"	"unprognostic (2.16e-1)"	"unprognostic (3.66e-2)"	"unprognostic (3.48e-1)"	"prognostic unfavorable (2.94e-14)"	"unprognostic (2.29e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.53e-1)"	"unprognostic (1.82e-1)"	16.6	6.3	6.9	18.5	8.2	20.2	10.9	6.8	9.4	7.3	5.6	5.7	507.2	3.8	1.7	9.0	5.6	9.2	17.8	6.9	7.0	3.3	4.4	6.2	33.4	7.2	8.2	2.1	5.3	1.5	1.3	4.6	7.2	4.3	3.6	0.3	4.7	2.8	5.3	6.0	17.9	5.7	6.1	17.5	46.0	2.4	8.7	259.0	5.8	6.4	26.4	9.3	5.4	8.8	14.0	37.7	19.2	13.2	35.6	48.7	30.5	13.7	7.8	13.2	9.3	17.5	14.8	38.4	15.8	17.9	24.7	2.2	13.2	55.1	7.3	2.9	17.2	7.8	6.6	13.5	15.0	6.3	20.3	234.3	23.2	5.1	9.0	12.6	50.3	570.9	20.4	30.7	6.0	33.1	1915.5	28.9	5.2	17.2	13.5	102.3	25.8	95.0	2.3	0.0	0.7	9.3	20.2	4.4	24.2	24.0	4.5	19.1	16.9	10.1	18.6	20.5	2.8	40.1	27.3	82.3	3.5	32.5	9.0	0.5	9.8	1.2	43.3	168.5	27.8	7.5	35.5	51.0	35.2	7.6	27.3	38.6	2.5	94.5	362.8	218.6	29.8	57.4	6.9	8.2	6.8	9.4	6.9	7.0	7.2	8.2	7.2	6.1	8.7	8.8	18.2	0.0	1.9	2.9	13.5	12.9	3.4	10.0	13.6	0.0	2.7	3.2	2.1	0.0	4.8	1.8	0.0	2.9	76.4	0.8	0.0	3.7	0.4	0.7	9.1	17.0	0.0	10.7	0.2	19.7	128.2	19.7	14.8	0.8	0.0	3.5	7.1	3.6	28.5	0.0	0.2	1.5	10.2	20.8	25.5	1.8	42.3	27.6	8.8	3.7	37.4	3.8	56.7	0.5	9.4	10.7	0.3	2.6	31.4	6.0	0.7	3.0	2.4	0.0	13.1	1.9	14.1	0.3	6.2	12.9	13.9	3.7	30.9	6.8	4.9	2.7
ADA2	"ADGF, CECR1, IDGFL"	ENSG00000093072	"Adenosine deaminase 2"	Q9NZK5	22	17178790-17258235	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"		"Heparin-binding, Hydrolase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 106.3"	"Cell type enhanced"	"Detected in many"		"Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6"					"Low region specificity"	"Detected in all"			HPA007888	Uncertain				"Secreted to blood"	NA	NA		58000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 16: Immune cells - Immune response"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 41: Macrophages - Immune response"			"HPA007888: AB_1078495"	"unprognostic (1.03e-3)"	"unprognostic (2.00e-3)"	"unprognostic (6.59e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.48e-2)"	"unprognostic (7.01e-3)"	"unprognostic (4.48e-2)"	"unprognostic (3.09e-3)"	"unprognostic (3.80e-2)"	"prognostic favorable (9.26e-4)"	"prognostic favorable (8.91e-4)"	"unprognostic (1.41e-1)"	"unprognostic (1.49e-1)"	"unprognostic (4.86e-3)"	"unprognostic (1.96e-2)"	"unprognostic (4.83e-2)"	"unprognostic (2.51e-1)"	14.0	11.3	8.3	39.4	9.9	22.8	17.6	10.6	7.9	22.0	20.5	28.3	18.1	19.9	2.7	12.0	51.5	32.1	39.6	7.8	10.9	14.5	21.1	54.9	47.3	16.3	11.4	12.1	13.9	5.4	22.5	15.2	14.7	15.4	34.3	11.0	15.6	17.1	3.4	4.7	26.1	23.4	13.7	106.3	19.6	18.4	12.9	53.7	16.9	4.3	60.7	34.7	6.5	21.1	0.0	0.0	6.4	0.0	0.2	0.8	0.3	2.3	0.1	0.0	0.0	0.0	23.7	6.0	21.4	7.2	0.0	0.5	0.2	0.0	0.0	0.1	0.0	1.1	0.0	0.1	4.0	0.3	0.3	11.3	0.1	0.0	0.1	0.1	24.0	9.0	0.1	44.9	0.9	0.0	38.9	1.1	17.8	0.0	0.1	1.2	0.0	6.5	0.0	9.3	10.9	0.1	0.1	0.0	0.0	19.1	0.2	9.7	3.0	0.1	0.2	0.0	0.0	23.8	2.3	1.7	0.0	39.6	0.0	17.5	212.9	11.3	34.6	204.9	26.8	25.8	27.4	34.1	139.1	19.7	31.6	32.4	10.5	44.9	176.1	57.4	17.2	170.7	8.3	9.9	10.6	7.9	7.8	10.9	16.3	11.4	14.7	13.7	12.9	21.1	8.7	0.0	16.8	0.0	7.2	0.0	0.0	0.0	0.0	0.0	5.1	4.2	0.0	0.0	11.2	5.5	0.0	0.4	13.7	0.0	7.9	1.7	0.0	27.6	6.6	2.2	0.0	0.0	0.0	5.2	0.9	2.1	0.0	22.0	5.1	12.6	0.0	0.0	57.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	62.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	1.8	0.0	0.0	12.4	0.0	0.0	3.1	15.3	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.8	8.2	3.1	0.0	0.0
ADCY1	"AC1, DFNB44"	ENSG00000164742	"Adenylate cyclase 1"	Q08828	7	45574140-45723116	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Biological rhythms, cAMP biosynthesis"	"Calmodulin-binding, Lyase"	"Cancer-related genes, Deafness, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"brain: 33.7;liver: 19.2;retina: 53.0"	"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 521.3;Excitatory neurons: 147.2;Inhibitory neurons: 117.9;Rod photoreceptor cells: 174.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"hTERT-HME1: 22.2;SH-SY5Y: 25.5;SK-MEL-30: 30.1;WM-115: 17.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018364, HPA068274"	Uncertain		Approved	Mitochondria		NA	NA				"Cluster 58: Brain - Synaptic function"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 9: Photoreceptor cells - Phototransduction"	Mitochondria		"CAB018364: AB_2223098, HPA068274: "	"unprognostic (9.41e-3)"	"unprognostic (7.30e-4)"	"unprognostic (9.31e-2)"	"unprognostic (2.98e-1)"	"unprognostic (4.18e-2)"	"unprognostic (3.07e-3)"	"unprognostic (1.32e-1)"	"unprognostic (7.31e-2)"	"unprognostic (1.64e-3)"	"unprognostic (2.89e-1)"	"unprognostic (7.73e-3)"	"unprognostic (1.54e-1)"	"unprognostic (4.74e-6)"	"unprognostic (2.49e-1)"	"unprognostic (7.65e-3)"	"unprognostic (2.87e-1)"	"unprognostic (2.23e-1)"	1.9	1.8	13.7	0.3	22.4	0.0	4.7	15.4	33.7	5.3	0.0	0.4	0.2	1.8	0.5	0.6	2.0	0.6	2.9	31.9	0.0	1.9	19.2	0.6	0.4	1.2	0.9	0.9	3.3	1.9	2.6	0.4	1.1	2.8	0.4	53.0	0.3	1.2	7.7	0.4	0.3	0.9	0.0	1.7	1.1	2.8	4.0	0.3	2.4	8.5	0.3	0.8	1.3	24.5	0.8	5.9	2.1	3.2	4.1	0.1	4.0	0.2	0.0	0.8	0.3	0.6	0.0	0.0	0.2	0.2	5.8	1.9	3.8	0.3	0.1	10.7	2.7	0.0	0.0	0.6	0.0	0.2	0.1	4.9	2.8	0.5	22.2	0.0	0.1	8.6	0.3	7.0	0.3	7.1	0.0	0.0	8.3	5.1	0.0	0.0	0.0	11.7	0.0	5.7	13.4	25.5	2.1	0.0	30.1	3.1	2.0	3.5	0.0	0.6	4.2	0.5	3.6	0.0	0.0	0.0	0.0	0.0	17.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	13.7	22.4	15.4	33.7	31.9	0.0	1.2	0.9	1.1	0.0	4.0	24.5	3.5	0.0	0.0	30.7	0.3	0.3	0.6	0.0	0.0	43.8	10.6	5.7	11.4	2.8	0.0	0.0	521.3	0.1	0.3	0.5	1.9	0.0	2.9	1.0	23.1	10.8	31.2	0.0	147.2	0.9	0.2	4.2	0.0	0.7	0.0	0.2	15.7	52.3	0.3	42.1	117.9	1.0	2.0	3.2	0.4	0.7	1.8	0.2	3.6	17.8	0.0	13.8	0.0	63.3	4.0	0.5	0.1	7.5	0.1	2.6	0.0	0.4	0.0	174.4	0.0	2.3	8.8	0.5	6.8	0.1	0.1	0.0	0.6	0.6	0.6	0.3
ADCY10	"HCA2, RP1-313L4.2, SAC, SACI, Sacy"	ENSG00000143199	"Adenylate cyclase 10"	Q96PN6	1	167809386-167914215	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"liver: 6.1;testis: 17.6"	"Group enriched"	"Detected in some"	7	"Early spermatids: 87.5;Late spermatids: 85.4"	"Cancer enhanced"	"Detected in single"		"liver cancer: 0.7"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"T-47d: 1.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA015243, HPA017749"	Approved					NA	NA				"Cluster 78: Testis - Spermatogenesis"	"Cluster 6: T47d - Mammary gland"	"Cluster 34: Spermatids - Unknown function"			"HPA015243: AB_1856540, HPA017749: AB_1856541"	"unprognostic (1.20e-1)"	"unprognostic (2.53e-1)"	"unprognostic (1.95e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.65e-1)"	"unprognostic (5.35e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.63e-1)"	"unprognostic (3.65e-1)"	"unprognostic (4.43e-2)"	"unprognostic (7.83e-5)"	"unprognostic (5.86e-7)"	"unprognostic (4.73e-2)"	"unprognostic (1.33e-1)"	"unprognostic (7.83e-2)"	"unprognostic (2.59e-1)"	0.1	0.2	1.3	0.0	1.2	0.0	1.0	2.6	2.4	0.2	0.7	0.3	0.3	0.1	0.1	0.1	0.1	0.1	0.2	1.4	0.7	0.4	6.1	0.2	0.0	0.6	0.8	0.1	0.4	0.0	0.1	0.1	0.7	0.4	0.2	0.2	0.1	0.1	0.1	0.1	0.2	0.1	0.6	0.1	0.3	17.6	1.2	0.1	0.1	0.0	0.0	0.1	0.1	1.7	0.1	0.0	0.0	0.0	0.1	0.1	0.7	0.0	0.2	0.0	0.3	0.4	0.0	0.0	0.1	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.4	0.1	0.1	0.2	0.0	0.0	0.0	0.0	0.5	0.2	0.1	0.0	0.0	0.2	0.3	0.0	0.0	0.0	0.1	0.2	0.2	0.2	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.1	0.4	1.4	0.2	0.0	0.0	0.0	0.0	0.0	0.3	0.1	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	1.3	1.2	2.6	2.4	1.4	0.7	0.6	0.8	0.7	0.6	1.2	1.7	0.1	0.0	0.0	2.0	0.0	0.5	0.2	0.0	0.0	0.0	0.3	0.3	0.6	0.0	0.0	0.0	0.0	0.9	0.0	0.4	0.0	0.0	87.5	0.3	0.2	0.1	0.0	0.0	9.9	0.0	0.7	0.3	0.0	0.1	0.0	0.9	0.7	7.6	0.1	0.0	7.6	0.0	0.0	0.0	0.4	85.4	0.6	0.1	0.0	1.0	0.0	0.0	0.0	3.5	3.6	0.0	0.0	0.4	0.0	0.2	1.1	0.2	0.0	0.0	0.0	0.2	0.4	11.3	0.6	0.1	0.4	1.8	0.0	0.8	0.2	0.2
ADCY2	"AC2, HBAC2, KIAA1060"	ENSG00000078295	"Adenylate cyclase 2"	Q08462	5	7396138-7830081	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"brain: 50.8;skeletal muscle: 68.3;tongue: 30.8"	"Group enriched"	"Detected in many"	5	"Astrocytes: 647.1;Excitatory neurons: 406.6;Horizontal cells: 201.9;Inhibitory neurons: 423.9;Oligodendrocyte precursor cells: 181.5"	"Cancer enhanced"	"Detected in some"		"glioma: 4.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	7	"AF22: 5.6;NTERA-2: 4.3;SK-MEL-30: 4.6;SuSa: 3.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB031482, HPA038015, HPA038483"	Approved					NA	NA				"Cluster 80: Striated muscle - Unknown function"	"Cluster 12: NES - Nervous system development"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"			"CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799"	"unprognostic (6.48e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.49e-1)"	"unprognostic (5.65e-2)"	"unprognostic (3.77e-1)"	"unprognostic (4.03e-4)"	"unprognostic (1.94e-2)"	"unprognostic (1.60e-2)"	"unprognostic (2.20e-1)"	"unprognostic (1.48e-1)"	"unprognostic (2.67e-2)"	"unprognostic (7.68e-2)"	"unprognostic (1.09e-5)"	"unprognostic (1.05e-1)"	"unprognostic (7.33e-3)"	"unprognostic (4.90e-2)"	"unprognostic (3.92e-3)"	1.4	2.2	32.3	0.3	39.1	0.1	1.8	25.9	39.9	4.5	8.0	3.2	0.9	3.2	0.6	3.0	3.0	1.1	0.4	38.2	37.6	0.2	0.0	0.3	0.0	43.4	44.1	3.9	0.8	0.4	6.3	0.8	34.1	5.2	0.5	7.0	1.8	3.9	68.3	5.4	1.1	3.3	50.8	0.2	1.6	2.7	33.8	0.2	0.4	30.8	0.1	1.9	3.1	37.8	0.0	0.0	5.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	4.3	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	4.6	3.8	0.1	0.0	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	32.3	39.1	25.9	39.9	38.2	37.6	43.4	44.1	34.1	50.8	33.8	37.8	0.3	3.2	2.7	647.1	0.1	5.9	0.7	0.1	0.0	26.8	1.5	1.5	2.2	1.5	2.6	0.0	68.8	0.6	0.2	0.2	0.0	0.6	3.2	0.2	1.6	1.3	12.6	0.0	406.6	0.5	0.3	3.5	0.0	0.2	1.3	3.2	0.4	0.2	0.2	201.9	423.9	1.2	0.0	0.0	5.0	4.9	4.4	0.9	40.9	20.6	0.0	2.0	0.0	181.5	10.6	3.6	7.6	1.9	0.0	8.0	0.2	0.2	5.3	4.9	0.0	11.9	0.9	1.2	1.7	0.0	4.7	0.8	0.7	0.3	0.4	1.4
ADCY3	AC3	ENSG00000138031	"Adenylate cyclase 3"	O60266	2	24819169-24920237	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis, Olfaction, Sensory transduction"	"Calmodulin-binding, Lyase"	Obesity	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Leydig cells: 58.4;Sertoli cells: 111.7;Smooth muscle cells: 62.8;Theca cells: 92.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB010223	Approved					NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 48: Smooth muscle cells - ECM organization"			"CAB010223: AB_630839"	"unprognostic (3.05e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.91e-2)"	"unprognostic (1.39e-3)"	"unprognostic (5.01e-2)"	"unprognostic (7.66e-2)"	"unprognostic (1.28e-1)"	"unprognostic (6.06e-2)"	"unprognostic (8.43e-2)"	"unprognostic (6.89e-2)"	"unprognostic (8.22e-3)"	"unprognostic (2.52e-1)"	"prognostic unfavorable (1.32e-9)"	"unprognostic (3.74e-2)"	"unprognostic (5.56e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.55e-3)"	94.4	17.3	43.5	17.3	55.1	17.7	74.6	36.7	50.1	66.7	28.4	27.5	10.9	56.4	20.5	30.4	62.1	23.0	36.6	43.3	43.4	25.9	6.6	42.5	18.9	41.6	43.8	71.9	15.7	17.0	41.7	83.6	41.1	40.6	15.8	4.2	21.6	33.0	15.2	38.4	34.4	35.3	36.9	30.4	25.0	9.8	50.6	11.4	36.8	20.4	18.1	36.4	48.9	44.9	76.5	40.4	17.2	28.3	84.5	75.4	29.6	32.3	65.9	37.1	37.8	38.6	25.1	26.0	6.2	53.2	51.0	54.5	43.1	54.5	24.0	58.4	55.8	43.0	40.0	1.7	64.0	24.0	24.6	55.7	47.5	36.6	50.8	23.6	33.8	27.9	15.5	49.2	19.3	43.6	17.9	2.1	14.9	39.9	24.4	38.8	75.3	59.5	15.5	38.7	31.6	19.1	45.8	54.2	30.2	13.0	13.5	22.5	33.5	59.7	34.2	39.1	54.1	42.4	101.6	113.6	18.7	39.2	31.4	2.6	1.5	0.0	0.4	1.6	0.3	5.5	0.9	0.5	9.5	6.0	0.7	0.5	0.0	1.2	0.4	9.0	3.4	1.0	43.5	55.1	36.7	50.1	43.3	43.4	41.6	43.8	41.1	36.9	50.6	44.9	14.6	0.0	1.8	17.0	8.2	11.0	4.2	4.1	5.2	3.0	18.6	8.0	2.8	0.0	1.3	1.8	0.0	1.0	5.2	5.0	0.0	0.9	0.3	1.9	42.2	10.6	1.2	5.2	40.1	0.0	2.1	25.5	2.0	2.2	18.4	3.7	5.0	0.3	12.6	0.0	36.8	6.0	2.0	5.4	6.9	3.9	58.4	10.1	7.2	21.5	4.0	1.6	0.0	15.1	33.2	1.0	5.8	29.3	4.9	11.2	8.3	0.2	1.1	2.2	111.7	6.5	62.8	0.4	2.4	4.4	11.8	1.2	7.2	92.9	12.1	3.9
ADCY4	AC4	ENSG00000129467	"Adenylate cyclase 4"	Q8NFM4	14	24318349-24335093	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	9	"basophil: 2.9"	"Lineage enriched"	"Detected in single"	9	"granulocytes: 2.9"	"Group enriched"	"Detected in some"	6	"HUVEC TERT2: 2.9;TIME: 5.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB005070, HPA048344"	Approved					NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"CAB005070: AB_2273639, HPA048344: AB_2680366"	"unprognostic (5.59e-2)"	"unprognostic (1.34e-1)"	"unprognostic (3.47e-4)"	"prognostic favorable (8.20e-4)"	"unprognostic (4.06e-1)"	"unprognostic (2.82e-3)"	"unprognostic (1.75e-4)"	"unprognostic (8.58e-2)"	"unprognostic (2.51e-2)"	"unprognostic (7.88e-2)"	"unprognostic (6.77e-2)"	"unprognostic (7.87e-2)"	"prognostic unfavorable (7.01e-4)"	"unprognostic (8.02e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	18.0	2.6	2.8	2.3	2.2	0.0	16.1	2.2	2.8	9.2	2.0	3.9	0.9	8.8	0.5	3.7	8.2	2.9	16.9	2.0	2.1	10.2	1.4	9.9	1.6	2.7	2.5	2.4	2.3	1.0	1.7	9.9	2.6	5.3	0.7	0.0	3.7	1.4	4.3	4.7	4.5	1.9	2.4	9.9	3.7	1.1	3.0	0.4	7.7	2.8	0.8	5.9	6.7	2.3	0.0	0.0	0.0	0.0	0.1	0.4	0.0	0.3	0.0	0.3	0.2	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.4	0.0	0.1	0.0	0.0	2.9	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	5.1	0.1	0.0	0.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.9	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	2.8	2.2	2.2	2.8	2.0	2.1	2.7	2.5	2.6	2.4	3.0	2.3	90.9	0.0	1.8	0.3	1.0	3.6	0.4	0.3	3.4	0.0	1.5	1.5	10.6	0.0	0.9	1.8	0.0	0.2	1.6	2.9	0.0	1.2	1.3	0.5	1.1	74.6	1.2	0.4	0.2	3.1	0.1	4.7	7.1	0.6	1.3	0.0	50.3	0.2	1.4	1.7	0.2	7.9	0.0	5.0	3.1	6.9	0.0	1.5	7.2	12.2	2.5	0.9	1.0	0.0	0.0	2.1	3.8	0.0	1.4	0.4	2.4	0.0	1.1	0.2	6.6	1.7	5.7	0.3	0.8	0.6	2.8	0.0	1.6	0.5	2.1	0.2
ADCY5	AC5	ENSG00000173175	"Adenylate cyclase 5"	O95622	3	123282296-123449090	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 97.7;heart muscle: 105.2"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 75.5;Inhibitory neurons: 44.0;Oligodendrocytes: 89.7;Paneth cells: 59.6;Peritubular cells: 73.7;Sertoli cells: 65.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"MCF7: 15.5;RPMI-8226: 2.7;RPTEC TERT1: 5.2"	"Region enriched"	"Detected in all"	5	"basal ganglia: 388.0"	"Region enriched"	"Detected in all"	6	"basal ganglia: 155.9"	"HPA017730, HPA077682"	Uncertain		Enhanced	"Intermediate filaments"		NA	NA				"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 54: Cardiomyocytes - Muscle contraction"	"Intermediate filaments"		"HPA017730: AB_1844595, HPA077682: AB_2686851"	"unprognostic (3.55e-2)"	"unprognostic (1.01e-3)"	"unprognostic (7.61e-3)"	"unprognostic (2.05e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.26e-2)"	"unprognostic (1.48e-1)"	"unprognostic (7.61e-2)"	"unprognostic (2.49e-2)"	"unprognostic (2.34e-1)"	"unprognostic (7.27e-3)"	"unprognostic (2.64e-2)"	"prognostic favorable (7.46e-6)"	"unprognostic (1.81e-2)"	"unprognostic (5.65e-2)"	"unprognostic (3.19e-2)"	"unprognostic (5.97e-4)"	18.9	3.3	25.5	4.9	97.7	0.0	10.6	13.9	43.9	9.8	0.0	35.1	5.2	14.7	5.7	18.8	12.7	10.0	105.2	25.8	15.9	12.8	3.3	4.1	2.3	20.5	18.3	13.2	7.5	0.8	14.3	6.1	17.4	19.8	5.6	4.5	4.0	21.5	2.7	2.6	13.0	18.2	10.8	6.5	21.2	8.2	34.4	1.3	1.9	5.8	3.0	23.2	7.8	30.1	0.0	0.6	1.3	0.1	0.1	0.1	0.3	0.0	0.0	0.3	0.0	0.1	0.1	0.0	0.3	0.2	2.3	0.5	0.6	0.0	0.0	0.1	0.8	0.0	0.2	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	15.5	0.0	0.0	0.8	0.0	0.1	0.0	0.3	2.7	5.2	0.5	1.8	1.6	0.0	0.5	0.1	1.7	0.0	0.1	0.0	0.1	1.2	0.1	0.2	0.1	0.6	0.0	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	25.5	97.7	13.9	43.9	25.8	15.9	20.5	18.3	17.4	10.8	34.4	30.1	0.3	0.0	0.0	8.1	0.1	0.3	0.1	0.2	0.0	21.8	0.4	5.8	75.5	8.6	0.0	7.3	0.0	1.4	0.0	2.6	0.0	15.9	0.9	1.5	7.1	1.8	0.0	0.0	34.0	6.9	4.0	5.2	0.0	4.0	0.0	4.6	3.9	0.1	0.3	0.0	44.0	0.3	0.0	0.0	0.3	3.0	20.5	0.1	0.0	6.5	1.0	1.0	0.0	19.1	89.7	0.4	59.6	73.7	0.0	0.1	0.3	0.8	0.0	2.2	65.7	0.6	21.4	0.8	6.3	0.2	0.9	12.4	0.2	1.0	2.0	0.1
ADCY6	AC6	ENSG00000174233	"Adenylate cyclase 6"	O43306	12	48766194-48789089	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 38.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"SK-BR-3: 68.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB018365	Approved		Approved	"Golgi apparatus"		NA	NA				"Cluster 46: Fibroblasts - ECM organization"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Golgi apparatus"		"CAB018365: AB_2257941"	"unprognostic (1.18e-2)"	"unprognostic (2.20e-2)"	"unprognostic (6.89e-2)"	"unprognostic (1.31e-1)"	"unprognostic (3.84e-2)"	"unprognostic (3.68e-2)"	"prognostic unfavorable (8.23e-4)"	"unprognostic (1.55e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.29e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.64e-2)"	"unprognostic (5.06e-3)"	"unprognostic (5.10e-3)"	"unprognostic (1.09e-1)"	"unprognostic (3.09e-1)"	"unprognostic (2.48e-2)"	43.2	15.0	8.9	6.1	7.9	1.3	23.7	5.0	9.2	19.3	10.3	26.3	18.7	20.7	19.0	10.3	17.1	13.9	57.2	8.0	11.2	21.1	9.6	13.5	3.9	5.5	5.4	22.3	22.3	20.7	14.6	14.5	6.6	16.3	20.3	5.7	33.5	16.5	12.1	15.3	21.4	13.6	1.9	4.8	25.1	4.0	14.4	2.8	17.9	12.7	3.2	12.3	12.8	6.4	14.0	25.9	30.2	18.9	32.0	15.9	32.0	16.7	17.1	19.8	13.8	45.7	45.3	0.0	37.2	15.3	8.2	10.9	9.2	11.6	7.9	0.1	13.4	12.5	37.8	8.4	17.6	0.0	10.1	20.0	13.6	17.1	6.5	37.9	18.7	0.8	1.7	4.5	15.6	23.1	0.0	0.5	10.3	21.6	12.3	4.6	11.4	7.7	23.4	41.5	4.5	18.4	17.2	68.0	15.2	13.3	53.3	3.5	21.1	18.3	13.1	9.7	7.4	7.0	3.7	0.4	16.9	0.0	8.6	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	8.9	7.9	5.0	9.2	8.0	11.2	5.5	5.4	6.6	1.9	14.4	6.4	11.6	0.0	6.4	18.3	0.6	2.7	3.3	7.5	4.0	10.1	22.7	15.0	8.2	7.2	9.8	18.4	20.9	7.4	0.4	38.8	0.0	5.8	0.8	6.8	8.0	8.1	8.4	0.0	17.5	4.0	2.7	7.6	14.3	11.3	1.3	14.6	5.0	7.7	2.5	10.1	18.8	24.9	8.2	0.6	2.8	1.1	11.5	0.7	7.2	7.5	0.6	3.4	0.0	15.1	7.0	9.5	30.3	9.4	0.3	6.3	26.0	2.8	5.8	9.3	19.7	9.5	26.6	1.9	1.7	3.6	2.0	5.1	0.8	13.9	23.7	9.3
ADCY7	"AC7, KIAA0037"	ENSG00000121281	"Adenylate cyclase 7"	P51828	16	50246137-50318135	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"dendritic cells: 42.8;granulocytes: 50.6;Kupffer cells: 65.1;Langerhans cells: 48.0;Macrophages: 45.4;Microglial cells: 52.5;monocytes: 42.4;NK-cells: 76.2"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEL: 81.0;HMC-1: 194.6;RPMI-8226: 100.6"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA041218, HPA048241"	Uncertain		Approved	Cytosol		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 63: NK-cells & T-cells - Immune response"	Cytosol		"HPA041218: AB_2677365, HPA048241: AB_2680326"	"unprognostic (1.98e-1)"	"prognostic unfavorable (5.31e-4)"	"unprognostic (1.24e-1)"	"unprognostic (1.78e-1)"	"unprognostic (3.77e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.90e-2)"	"unprognostic (7.75e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.56e-2)"	"unprognostic (1.65e-1)"	"unprognostic (1.18e-1)"	"unprognostic (5.59e-3)"	"unprognostic (7.34e-2)"	"unprognostic (2.15e-3)"	"unprognostic (2.18e-1)"	"unprognostic (9.52e-4)"	8.1	3.9	6.8	23.9	7.3	24.7	5.6	7.8	8.8	3.9	6.9	8.2	4.1	3.7	2.3	14.3	7.6	12.4	5.5	6.2	10.6	1.6	3.8	23.3	27.1	14.4	11.4	19.4	2.0	1.6	2.0	14.5	12.8	2.7	8.8	0.8	4.0	2.1	2.2	13.7	8.6	7.8	10.9	29.7	7.8	1.9	12.9	19.3	2.4	3.5	24.5	7.6	4.7	19.1	16.3	18.5	0.7	2.6	1.9	24.0	1.7	9.7	4.5	8.1	7.0	23.4	28.4	4.2	25.4	41.0	0.5	50.5	22.3	10.0	8.9	50.7	6.9	81.0	18.4	5.8	20.6	10.6	194.6	12.0	8.5	5.7	8.3	4.4	2.3	17.7	30.4	7.9	10.5	9.2	5.8	34.9	3.5	8.4	31.1	5.7	7.1	100.6	5.0	1.1	4.0	9.8	5.4	2.0	4.8	4.4	0.1	38.7	17.6	0.9	25.5	2.9	3.6	0.3	0.6	8.5	9.3	32.6	3.4	9.2	7.6	2.8	6.9	10.7	5.1	2.8	2.9	5.2	12.2	3.3	2.5	3.6	4.1	9.5	18.1	6.8	4.4	5.6	6.8	7.3	7.8	8.8	6.2	10.6	14.4	11.4	12.8	10.9	12.9	19.1	1.4	19.2	35.9	2.0	15.4	3.7	0.4	0.6	1.2	1.2	1.3	2.8	1.0	0.0	7.9	0.0	6.2	11.6	42.8	3.3	0.0	1.9	1.5	6.7	6.5	1.9	0.0	12.4	6.4	0.2	1.8	9.2	3.6	13.6	50.6	4.7	1.4	0.5	35.2	0.0	3.8	0.7	0.0	65.1	48.0	1.3	0.6	45.4	5.4	52.5	42.4	0.5	76.2	3.5	0.7	4.2	10.4	1.2	15.6	0.5	0.1	0.2	1.0	0.8	6.6	28.3	2.2	0.0	1.5	7.2	4.0	4.0	26.6	16.0	2.3	1.3
ADCY8	"AC8, ADCY3, HBAC1"	ENSG00000155897	"Adenylate cyclase 8"	P40145	8	130780301-131040909	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	7	"brain: 29.4;epididymis: 22.8"	"Group enriched"	"Detected in some"	5	"Astrocytes: 151.8;Inhibitory neurons: 250.9;Oligodendrocyte precursor cells: 138.7"	"Group enriched"	"Detected in some"	5	"glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC TERT1: 5.0;GAMG: 8.2;U-138 MG: 17.6;U-87 MG: 34.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018652, HPA024291"	Supported					NA	NA				"Cluster 68: Epididymis - Unknown function"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB018652: AB_633654, HPA024291: AB_1844597"	"unprognostic (5.59e-3)"				"unprognostic (3.10e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.09e-1)"	"unprognostic (2.78e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.05e-1)"	"unprognostic (8.22e-3)"	"unprognostic (4.91e-2)"	"unprognostic (7.39e-3)"	"unprognostic (1.92e-1)"	"unprognostic (2.44e-2)"	"unprognostic (6.67e-2)"		0.0	0.0	17.0	0.0	13.4	0.0	0.5	19.7	9.6	0.4	1.7	0.0	0.0	0.0	22.8	0.0	3.9	0.0	0.0	11.9	14.0	0.2	0.0	1.2	0.0	17.2	22.6	0.0	0.0	0.0	0.0	0.0	15.2	0.0	0.0	3.1	1.1	1.4	0.1	2.1	0.0	0.5	25.9	0.0	0.1	0.5	29.4	0.0	0.0	0.0	0.0	0.0	0.0	23.3	0.0	0.0	0.0	0.1	1.3	5.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	17.6	0.4	0.0	0.0	0.0	0.0	0.0	34.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	17.0	13.4	19.7	9.6	11.9	14.0	17.2	22.6	15.2	25.9	29.4	23.3	0.0	0.0	1.5	151.8	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.7	0.0	0.0	0.0	0.0	0.0	32.4	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	250.9	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	8.4	0.0	0.1	0.0	138.7	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.3	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0
ADCY9	AC9	ENSG00000162104	"Adenylate cyclase 9"	O60503	16	3953387-4116442	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"cAMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"choroid plexus: 45.4;skeletal muscle: 52.9"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 95.3;Inhibitory neurons: 72.7;Oligodendrocyte precursor cells: 42.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 40.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041328, HPA044225"	Approved		Approved	Cytosol		NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 20: HeLa - Mitochondria"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	Cytosol		"HPA041328: AB_2677414, HPA044225: AB_2678863"	"unprognostic (1.78e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.57e-1)"	"prognostic unfavorable (2.55e-5)"	"unprognostic (6.62e-2)"	"unprognostic (1.30e-2)"	"unprognostic (2.52e-1)"	"unprognostic (3.61e-2)"	"unprognostic (6.93e-2)"	"unprognostic (4.76e-3)"	"unprognostic (5.40e-2)"	"unprognostic (1.37e-1)"	"prognostic favorable (5.24e-8)"	"unprognostic (1.19e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.55e-2)"	6.9	5.6	5.1	4.4	7.6	1.5	6.1	3.2	7.5	8.2	45.4	8.2	8.2	8.0	2.4	8.4	9.2	6.9	14.9	10.7	0.0	9.4	11.9	14.0	1.9	3.0	0.6	11.2	15.8	9.1	5.1	9.9	0.9	4.4	6.8	2.9	11.9	5.8	52.9	5.9	9.6	7.9	0.1	4.4	6.4	4.0	1.3	2.1	18.8	28.6	2.6	9.7	6.1	5.2	8.5	12.9	3.8	7.0	13.3	16.0	5.6	14.5	15.1	8.0	6.3	10.6	7.2	0.0	21.8	40.1	4.8	8.0	14.9	9.1	5.4	10.4	14.3	0.3	29.4	20.3	14.2	1.1	6.4	17.1	13.6	9.3	4.9	6.6	5.4	2.7	4.7	0.0	8.3	15.3	0.1	4.4	6.9	3.6	6.9	13.3	18.0	0.4	2.9	2.3	8.7	3.8	11.3	13.2	9.6	4.2	33.5	15.0	4.9	15.8	4.3	15.6	6.4	3.2	2.1	1.7	3.4	4.4	6.3	0.8	0.3	0.2	0.4	0.3	0.4	0.0	0.1	0.1	0.0	0.0	0.0	0.2	0.1	0.3	0.0	0.2	0.0	0.3	5.1	7.6	3.2	7.5	10.7	0.0	3.0	0.6	0.9	0.1	1.3	5.2	7.0	12.8	12.8	33.3	1.0	6.4	1.1	3.9	5.2	10.6	4.2	3.7	17.3	22.8	7.1	12.9	12.5	1.8	5.8	19.5	0.0	4.5	0.8	6.1	10.5	6.3	1.2	0.4	95.3	5.3	1.8	8.1	1.5	5.7	0.0	15.3	8.2	19.9	1.5	1.7	72.7	7.6	2.0	4.7	2.0	2.2	8.4	3.3	7.2	31.9	2.6	5.5	4.1	42.3	12.5	3.5	4.3	7.5	2.5	1.1	15.0	5.6	9.5	14.9	0.0	9.4	12.5	1.1	5.0	0.9	3.8	1.0	3.4	4.8	7.2	1.3
ADK	AK	ENSG00000156110	"Adenosine kinase"	P55263	10	74151202-74709963	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Purine salvage"	"Kinase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 151.2"	"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 245.3;Inhibitory neurons: 287.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB032876, HPA038391, HPA038409, HPA075222"	Approved		Supported	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA		920000	"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Nucleoplasm, Cytosol"	"Plasma membrane"	"CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: "	"unprognostic (1.55e-3)"	"unprognostic (1.09e-1)"	"unprognostic (1.88e-1)"	"unprognostic (2.62e-2)"	"unprognostic (2.52e-2)"	"prognostic unfavorable (1.93e-4)"	"prognostic favorable (9.91e-4)"	"unprognostic (2.64e-1)"	"unprognostic (2.88e-1)"	"unprognostic (1.55e-1)"	"unprognostic (8.15e-3)"	"unprognostic (2.51e-1)"	"unprognostic (1.89e-3)"	"unprognostic (2.03e-1)"	"unprognostic (2.88e-2)"	"unprognostic (4.97e-3)"	"unprognostic (2.95e-2)"	23.9	15.5	13.0	16.9	18.7	28.6	27.4	13.5	17.7	17.5	11.6	17.9	16.9	10.8	16.5	47.3	16.5	11.4	27.2	13.9	15.2	35.8	151.2	24.4	22.8	14.0	15.0	8.3	18.8	44.2	14.9	26.6	16.5	14.9	19.5	16.1	20.0	16.0	41.5	33.9	12.4	14.8	14.2	15.0	12.1	15.5	14.1	27.0	38.2	47.1	34.5	24.5	24.7	15.8	177.3	37.4	37.2	50.5	37.1	54.7	88.2	140.8	105.4	103.8	114.5	114.0	172.6	86.3	34.2	57.7	51.3	151.1	44.1	150.1	167.0	59.1	51.3	55.6	59.8	122.8	41.7	87.6	22.5	51.1	95.5	77.4	191.7	79.0	91.2	38.7	41.8	28.4	78.8	101.7	102.5	129.0	9.9	80.0	276.3	100.6	63.7	69.4	117.1	92.7	29.5	33.8	63.6	239.7	49.5	34.7	159.7	69.3	82.8	34.3	67.0	93.2	123.0	40.5	48.3	98.1	65.0	127.6	22.1	2.3	34.2	4.1	12.9	65.5	29.9	103.7	28.2	24.1	83.1	155.0	21.3	19.2	11.1	20.7	80.4	57.6	55.7	36.3	13.0	18.7	13.5	17.7	13.9	15.2	14.0	15.0	16.5	14.2	14.1	15.8	9.8	83.3	75.8	136.5	84.2	94.2	73.5	102.0	105.9	16.3	26.2	26.0	67.8	38.6	72.4	31.3	56.3	136.7	25.9	11.0	92.0	83.2	80.7	40.6	18.8	14.9	10.8	27.7	245.3	67.5	139.5	27.0	23.0	55.6	21.5	9.7	17.2	130.1	39.3	11.8	287.7	12.1	44.7	25.2	50.0	26.9	16.8	33.7	48.0	198.6	44.1	14.1	11.3	140.8	165.4	62.7	10.4	12.0	39.1	92.1	5.0	64.5	33.5	25.0	6.6	20.4	26.0	17.4	14.3	96.7	97.0	107.3	32.7	17.0	20.5	66.3
ADPRM	"C17orf48, MDS006"	ENSG00000170222	"ADP-ribose/CDP-alcohol diphosphatase, manganese dependent"	Q3LIE5	17	10697594-10711558	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Rod photoreceptor cells: 34.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA023265, HPA023820"	Approved					NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 32: Non-specific - Translation"			"HPA023265: AB_1845590, HPA023820: AB_1845591"	"unprognostic (7.58e-3)"	"prognostic favorable (1.69e-4)"	"unprognostic (1.42e-1)"	"prognostic favorable (2.38e-5)"	"unprognostic (2.49e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.43e-2)"	"unprognostic (1.43e-1)"	"unprognostic (6.26e-3)"	"unprognostic (2.97e-1)"	"unprognostic (6.53e-3)"	"unprognostic (2.65e-2)"	"unprognostic (1.83e-1)"	"unprognostic (4.77e-2)"	"unprognostic (5.97e-2)"	6.7	4.6	1.9	4.9	2.2	6.6	6.6	2.0	2.3	6.8	1.7	5.1	3.1	6.4	3.7	4.4	4.8	4.7	3.6	1.9	2.1	4.5	6.8	3.9	6.9	1.9	1.8	7.8	6.9	3.1	3.9	2.6	1.9	7.7	3.2	9.9	4.7	3.5	9.2	5.4	6.0	2.8	2.0	5.8	7.9	4.0	2.2	7.0	6.5	6.4	5.6	4.8	5.2	2.4	3.8	2.8	3.9	5.0	8.8	11.1	1.9	7.2	7.7	5.2	7.5	1.5	1.7	7.1	3.3	7.5	2.2	3.0	1.8	5.2	6.4	4.4	5.4	3.5	2.9	4.3	14.7	2.6	4.3	13.7	7.5	5.6	7.8	8.0	9.6	7.8	3.4	0.6	6.8	1.1	2.8	4.5	4.2	2.5	1.5	3.1	2.7	1.9	9.1	2.5	0.7	5.2	3.5	1.3	8.2	4.7	3.6	5.0	9.8	2.9	2.3	3.6	4.2	1.6	1.1	1.1	6.9	3.6	6.1	2.6	2.5	4.7	2.4	2.6	3.5	5.9	6.2	4.1	3.1	7.2	13.0	8.5	2.3	4.1	2.3	1.7	5.9	3.9	1.9	2.2	2.0	2.3	1.9	2.1	1.9	1.8	1.9	2.0	2.2	2.4	5.8	3.2	2.0	6.5	17.6	5.2	11.7	17.4	8.0	11.7	5.9	6.0	2.7	4.3	8.9	1.8	18.8	7.2	6.4	3.8	3.9	8.4	10.2	1.9	3.9	5.7	4.8	6.7	6.0	8.3	7.3	6.6	4.6	2.4	14.0	4.4	7.1	9.8	6.7	3.3	6.9	7.5	2.0	9.5	5.1	5.2	15.8	6.0	10.6	1.9	11.1	13.5	6.2	8.0	8.1	8.1	4.6	8.2	3.6	12.7	14.9	8.5	4.1	34.3	6.6	6.6	14.0	12.5	10.2	4.4	4.7	8.2	13.0	4.4	5.6	11.4
ADSL		ENSG00000239900	"Adenylosuccinate lyase"	P30566	22	40346461-40390463	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Purine biosynthesis"	Lyase	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	6	"skeletal muscle: 345.1;tongue: 242.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000525, CAB019285"	Enhanced		Enhanced	Cytosol		NA	NA		440000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"CAB019285: , HPA000525: AB_1078106"	"unprognostic (2.80e-1)"	"unprognostic (2.12e-1)"	"prognostic favorable (2.38e-4)"	"unprognostic (2.64e-1)"	"unprognostic (1.02e-1)"	"unprognostic (6.87e-3)"	"prognostic unfavorable (5.81e-8)"	"unprognostic (1.35e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.99e-1)"	"unprognostic (6.28e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.99e-2)"	"unprognostic (8.43e-2)"	"unprognostic (2.70e-1)"	"unprognostic (4.06e-1)"	"unprognostic (1.44e-2)"	29.8	33.9	10.6	31.1	11.2	40.6	33.1	12.5	13.3	30.7	12.9	36.5	22.7	34.9	21.9	29.8	33.5	20.6	47.4	10.9	10.6	33.6	32.1	22.7	46.9	10.5	11.7	33.5	45.2	29.3	22.0	30.2	10.9	23.8	35.4	10.3	25.7	22.3	345.1	22.2	28.8	41.1	10.0	33.5	28.0	29.2	10.5	50.5	29.6	242.3	48.5	36.0	25.2	10.8	98.0	110.2	88.3	124.9	62.6	89.5	106.5	82.0	85.2	187.3	138.1	189.0	51.9	279.0	73.2	102.3	84.9	67.3	203.5	137.4	187.7	75.3	197.5	126.5	98.4	166.5	134.6	423.0	96.3	97.7	76.5	161.5	169.8	91.3	138.9	127.3	153.1	114.3	136.4	105.0	130.2	131.2	152.5	121.3	119.3	195.1	203.6	198.2	118.9	67.8	58.8	54.4	106.2	54.1	170.7	78.5	76.8	134.7	91.2	93.3	173.7	85.3	168.8	109.0	212.6	218.2	80.9	149.5	97.7	29.0	47.2	19.9	35.5	55.2	49.5	34.6	76.1	48.5	68.1	33.5	58.3	45.0	4.1	48.2	49.7	34.4	81.7	62.3	10.6	11.2	12.5	13.3	10.9	10.6	10.5	11.7	10.9	10.0	10.5	10.8	10.0	12.8	10.8	9.4	28.3	18.1	18.8	48.6	23.9	16.1	14.8	15.0	30.0	30.0	20.8	3.7	37.5	85.3	15.5	13.0	7.9	61.3	44.0	5.6	9.2	21.6	13.8	54.6	11.4	43.7	78.9	21.2	21.4	5.6	36.8	8.8	28.9	25.6	60.3	6.7	10.7	24.1	24.4	44.8	26.7	25.2	24.8	22.7	12.4	1.0	41.9	45.1	19.6	9.5	9.8	33.7	15.6	14.3	52.4	21.3	21.4	19.7	12.3	18.1	26.3	38.5	20.8	61.2	82.8	35.7	15.2	33.1	32.2	8.7	37.7	14.1
ADSS1	"ADSSL1, FLJ38602"	ENSG00000185100	"Adenylosuccinate synthase 1"	Q8N142	14	104724229-104747325	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Purine biosynthesis"	Ligase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	9	"skeletal muscle: 1273.1;tongue: 609.8"	"Cell type enriched"	"Detected in some"	20	"Cardiomyocytes: 137.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"EFO-21: 15.2;MCF7: 14.2;OE19: 23.2;SiHa: 23.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA052621	Enhanced					NA	NA		290000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 21: OE19 - Mitochondria"	"Cluster 54: Cardiomyocytes - Muscle contraction"			"HPA052621: "	"unprognostic (2.23e-2)"	"unprognostic (3.15e-1)"	"unprognostic (1.72e-3)"	"unprognostic (5.14e-2)"	"unprognostic (2.81e-3)"	"unprognostic (3.46e-1)"	"unprognostic (1.70e-2)"	"unprognostic (1.15e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.58e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.35e-1)"	"prognostic unfavorable (4.99e-4)"	"unprognostic (2.33e-1)"	"unprognostic (2.35e-1)"	"unprognostic (2.18e-2)"	"unprognostic (2.78e-2)"	8.1	5.1	3.8	1.0	6.8	0.9	4.4	6.6	5.6	4.1	7.6	3.0	2.7	3.3	4.5	18.5	6.5	5.7	100.2	3.7	6.7	14.8	28.8	3.1	1.1	6.0	6.0	2.7	7.9	7.3	10.0	7.3	6.1	7.6	1.4	10.1	10.7	4.0	1273.1	5.5	2.8	2.3	5.2	2.0	6.5	18.5	5.5	1.0	7.4	609.8	0.8	6.5	5.4	7.7	0.1	3.2	2.4	7.1	1.7	1.1	0.8	0.9	1.3	0.2	0.7	0.2	2.5	0.0	15.2	0.8	0.5	1.3	0.2	0.5	0.6	1.0	0.5	0.1	7.9	1.1	1.8	0.0	6.0	3.2	2.3	0.0	2.6	2.7	0.4	0.3	2.9	0.1	1.2	14.2	0.0	0.7	2.1	23.2	1.3	0.2	0.3	0.9	0.5	1.7	2.0	4.2	23.1	1.0	3.3	1.8	7.1	2.1	0.8	0.1	0.6	1.6	0.1	4.4	3.5	0.0	2.2	1.0	1.5	0.0	0.0	0.2	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	3.8	6.8	6.6	5.6	3.7	6.7	6.0	6.0	6.1	5.2	5.5	7.7	0.5	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	137.4	0.0	0.0	0.0	0.0	3.9	0.2	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	1.7	6.6	0.0	0.0	0.0	0.0	0.0	0.0	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.1	0.0	0.0	0.0	0.0	1.5	0.1	0.0	0.0	0.0
ADSS2	ADSS	ENSG00000035687	"Adenylosuccinate synthase 2"	P30520	1	244408494-244451909	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	Ligase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 26.4;Cytotrophoblasts: 49.3;dendritic cells: 59.6;Extravillous trophoblasts: 97.2;Hofbauer cells: 35.8;Syncytiotrophoblasts: 54.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA024400	Supported		Approved	"Plasma membrane,Cytosol"		NA	NA		690000	"Cluster 38: Basophils - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 24: Non-specific - Transcription regulation"	Cytosol	"Plasma membrane"	"HPA024400: AB_1844623"	"unprognostic (4.24e-3)"	"unprognostic (2.63e-1)"	"unprognostic (3.95e-2)"	"unprognostic (8.68e-2)"	"unprognostic (6.91e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.62e-2)"	"unprognostic (2.58e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.44e-2)"	"unprognostic (3.10e-1)"	"unprognostic (1.35e-1)"	"unprognostic (7.62e-2)"	"unprognostic (1.86e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.18e-2)"	19.8	20.5	17.8	28.1	22.0	43.9	34.6	21.7	26.7	25.9	17.0	28.7	28.7	23.4	29.8	32.6	23.9	21.0	8.9	19.2	21.1	32.9	24.3	25.3	31.9	21.9	19.6	21.7	19.8	27.6	14.5	28.6	23.1	25.3	29.8	11.4	22.8	25.6	10.8	33.2	27.1	25.2	19.6	23.7	35.0	70.3	20.9	33.8	34.9	8.4	34.9	36.2	21.5	28.7	89.9	48.6	41.6	36.9	47.6	67.8	76.2	88.5	74.4	62.3	47.0	64.6	84.5	79.7	57.1	68.9	26.6	66.1	45.9	58.0	69.5	59.6	81.0	53.1	47.8	49.3	57.1	127.1	65.6	46.8	68.5	58.1	58.3	72.1	225.6	43.3	94.0	57.7	62.7	21.6	82.3	85.0	110.5	85.0	53.1	74.9	39.4	86.5	103.8	55.2	56.2	49.2	75.2	69.0	91.4	43.9	48.0	66.7	99.4	57.1	31.3	67.0	93.7	69.1	97.2	60.0	47.2	146.8	86.3	48.3	22.8	20.0	20.4	29.9	22.0	15.3	18.6	17.8	20.1	12.3	15.6	17.9	17.5	23.6	33.6	7.9	22.3	18.8	17.8	22.0	21.7	26.7	19.2	21.1	21.9	19.6	23.1	19.6	20.9	28.7	26.4	0.0	0.0	0.0	7.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.4	0.0	0.0	0.0	0.0	49.3	59.6	0.0	0.0	0.0	0.0	0.0	0.0	3.4	0.0	0.0	0.0	0.0	97.2	9.3	0.0	0.0	0.0	0.0	0.0	0.0	35.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	19.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.3	0.0	0.0	0.0	0.0	54.0	11.0	0.0	0.0	0.0
AK1		ENSG00000106992	"Adenylate kinase 1"	P00568	9	127866486-127877675	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase"	"Disease variant, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 1346.2;tongue: 783.3"	"Cell type enhanced"	"Detected in all"		"Early spermatids: 281.3;Late spermatids: 1031.8;Muller glia cells: 287.6;Peritubular cells: 386.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"U-2197: 163.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006456, CAB009893"	Enhanced		Supported	Cytosol		NA	NA		24000000	"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 18: U-2197 - ECM organization"	"Cluster 31: Spermatids - Spermatogenesis"	Cytosol		"CAB009893: AB_2225151, HPA006456: AB_1078116"	"unprognostic (6.07e-3)"	"unprognostic (1.44e-2)"	"unprognostic (2.36e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.44e-1)"	"unprognostic (3.09e-1)"	"unprognostic (1.52e-2)"	"unprognostic (3.12e-2)"	"unprognostic (2.19e-1)"	"unprognostic (5.74e-2)"	"unprognostic (6.65e-3)"	"unprognostic (2.07e-1)"	"unprognostic (1.81e-2)"	"prognostic favorable (7.31e-4)"	"unprognostic (2.62e-1)"	"unprognostic (8.40e-3)"	"unprognostic (6.99e-3)"	28.5	34.5	81.3	11.5	79.2	28.4	17.0	87.9	95.1	37.5	145.8	33.8	17.9	14.3	28.5	32.0	342.2	22.5	270.0	79.5	88.5	31.4	26.5	74.6	5.0	97.4	99.8	45.0	14.9	47.0	33.8	7.6	99.0	17.1	39.5	29.0	33.1	35.9	1346.2	14.2	12.1	21.9	105.0	20.8	23.9	63.1	89.4	3.9	34.8	783.3	12.6	19.7	19.4	97.2	56.7	23.6	30.1	40.4	71.2	142.9	27.4	38.3	38.2	66.7	40.4	18.0	34.9	1.5	40.8	79.4	44.1	79.2	0.3	43.1	26.6	9.0	26.1	8.3	65.2	31.6	40.1	0.0	1.0	110.9	81.8	49.9	35.5	36.8	90.3	0.8	33.7	2.3	76.7	53.5	0.1	1.1	10.6	139.7	74.2	1.3	30.0	12.6	44.8	4.1	48.3	30.4	101.0	57.4	29.8	15.3	45.8	33.3	75.9	45.9	18.8	163.8	37.3	3.5	0.6	0.2	57.7	0.3	32.4	0.2	0.0	0.1	0.3	0.0	0.2	0.0	0.1	0.2	0.0	0.2	0.0	0.2	0.5	0.2	0.1	0.9	0.0	0.3	81.3	79.2	87.9	95.1	79.5	88.5	97.4	99.8	99.0	105.0	89.4	97.2	12.8	41.7	148.1	25.8	2.6	26.4	17.2	84.5	6.2	54.6	11.5	7.9	49.7	28.6	79.4	7.3	16.7	7.5	5.7	210.1	17.6	116.7	281.3	7.3	8.0	39.8	106.3	97.0	11.1	60.9	46.8	37.3	46.4	4.8	1.3	2.7	49.2	77.3	59.3	48.8	12.0	62.7	120.1	3.7	22.3	1031.8	226.5	7.9	83.6	2.8	2.3	287.6	10.3	4.5	9.7	57.2	132.7	386.3	4.2	14.4	22.8	8.2	186.5	69.5	26.3	107.2	56.4	20.2	16.7	33.6	28.4	13.5	7.1	83.4	65.5	25.3
AK2		ENSG00000004455	"Adenylate kinase 2"	P54819	1	33007940-33080996	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase"	"Disease variant, SCID"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 440.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA018479, CAB079913"	Approved		Approved	Mitochondria		NA	NA		1100000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 32: U-937 - Innate immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"CAB079913: AB_2546087, HPA018479: AB_1844676"	"prognostic favorable (4.37e-4)"	"unprognostic (3.25e-2)"	"unprognostic (2.80e-2)"	"prognostic unfavorable (8.65e-4)"	"unprognostic (3.16e-2)"	"unprognostic (8.21e-2)"	"prognostic unfavorable (9.32e-4)"	"unprognostic (7.86e-3)"	"unprognostic (1.85e-2)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (6.40e-4)"	"unprognostic (4.95e-2)"	"unprognostic (8.33e-3)"	"unprognostic (9.56e-3)"	"unprognostic (2.71e-1)"	"unprognostic (1.40e-1)"	"unprognostic (5.40e-3)"	85.3	88.6	39.9	76.9	45.0	74.3	80.4	44.1	49.0	79.6	49.8	117.2	140.0	58.6	52.1	108.5	65.3	49.0	114.1	38.8	43.8	181.6	172.9	59.3	73.3	48.5	42.8	59.9	78.9	123.6	49.4	68.4	50.4	63.2	114.0	51.0	81.1	55.5	154.2	74.4	139.4	68.1	44.0	57.2	92.7	54.8	44.3	85.9	86.6	122.9	113.4	84.2	76.9	49.3	339.1	153.4	131.6	149.7	94.9	116.6	132.8	185.0	143.5	267.7	280.2	283.2	311.9	602.1	218.4	139.8	204.2	235.4	312.5	327.0	276.6	261.6	229.3	396.2	270.0	219.9	218.2	712.5	222.2	118.1	238.2	232.7	471.2	163.3	190.2	245.7	436.9	230.4	165.0	174.2	273.0	392.8	181.2	337.4	222.4	314.7	222.2	415.6	286.2	205.1	190.8	114.8	205.4	235.0	584.8	151.4	194.5	517.2	138.9	165.5	194.3	259.4	357.5	238.0	324.7	565.7	232.4	664.6	195.5	49.2	158.8	198.0	77.1	145.5	81.8	122.3	72.7	74.0	195.8	105.8	72.9	67.9	42.1	115.3	130.4	154.2	96.8	188.1	39.9	45.0	44.1	49.0	38.8	43.8	48.5	42.8	50.4	44.0	44.3	49.3	60.5	51.3	79.0	19.6	44.0	125.2	101.4	228.1	63.7	21.1	66.5	72.6	106.9	71.4	142.8	112.2	83.4	158.0	37.0	109.6	256.3	120.2	108.3	50.0	42.1	70.7	50.4	50.9	16.2	123.7	164.6	58.0	66.3	47.0	40.0	38.8	41.4	135.5	96.1	8.4	19.7	84.7	89.5	44.8	60.1	42.8	46.9	48.4	87.2	12.2	67.3	22.1	48.4	14.1	22.0	110.5	67.2	44.0	55.7	109.0	236.9	440.0	67.0	41.8	52.6	34.1	108.4	91.0	31.6	88.6	122.7	216.6	40.7	72.2	122.6	120.5
AK3	"AK3L1, AK6, AKL3L1"	ENSG00000147853	"Adenylate kinase 3"	Q9UIJ7	9	4709556-4742043	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 242.8"	"Cell type enhanced"	"Detected in all"		"Hepatocytes: 305.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 485.4;HEL: 273.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA063324	Enhanced		Supported	Mitochondria		NA	NA		31000	"Cluster 15: NK-cells - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"HPA063324: AB_2684985"	"unprognostic (1.30e-2)"	"unprognostic (2.25e-1)"	"unprognostic (1.28e-1)"	"unprognostic (1.06e-1)"	"unprognostic (6.55e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.21e-3)"	"unprognostic (6.44e-2)"	"unprognostic (2.81e-2)"	"unprognostic (9.81e-3)"	"unprognostic (1.90e-1)"	"unprognostic (2.76e-2)"	"prognostic favorable (6.07e-9)"	"unprognostic (1.24e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.55e-3)"	75.5	62.9	30.1	23.7	36.9	20.1	39.7	33.5	34.9	41.0	56.2	67.4	68.3	41.9	31.2	61.2	34.4	35.9	100.6	27.0	40.6	101.4	199.9	34.9	29.6	32.8	38.1	47.8	38.9	66.8	22.2	35.1	33.7	49.2	59.6	16.8	38.7	42.6	242.8	47.4	62.5	41.7	33.5	33.0	69.5	11.2	37.9	35.1	49.9	159.6	34.4	48.7	39.7	36.5	44.1	30.7	55.5	22.6	75.3	55.5	4.9	60.4	116.1	30.4	45.5	5.7	43.6	39.5	20.4	63.5	16.6	29.3	40.8	48.0	51.2	485.4	37.1	273.3	56.1	91.3	58.5	28.7	14.1	87.9	41.4	26.4	36.0	70.4	91.2	38.2	22.1	49.6	91.8	22.5	27.5	65.6	53.3	77.1	15.4	38.2	21.1	19.2	82.1	55.7	98.3	63.6	65.7	18.5	35.1	53.7	26.5	53.2	65.9	25.7	28.8	70.1	43.6	15.5	10.5	50.3	46.9	19.9	18.9	13.3	10.2	32.2	27.6	8.1	25.5	12.1	21.6	25.7	19.6	12.3	28.4	29.2	2.8	27.4	6.5	26.3	31.8	21.1	30.1	36.9	33.5	34.9	27.0	40.6	32.8	38.1	33.7	33.5	37.9	36.5	58.3	57.7	80.3	78.0	34.0	74.2	76.4	87.4	84.2	10.7	58.8	28.3	182.9	68.6	71.0	66.2	22.9	95.5	34.6	129.9	258.2	84.8	3.7	40.7	30.6	65.7	109.6	68.1	23.4	69.6	17.0	83.4	87.1	37.8	46.2	75.8	79.2	305.6	47.5	15.2	55.8	104.2	73.2	46.9	41.4	4.5	108.7	34.7	74.7	22.5	40.9	28.2	33.0	44.7	87.0	67.3	78.7	149.7	62.8	166.7	111.8	183.5	52.8	11.0	105.2	76.0	60.8	6.4	14.1	152.5	104.4	214.0	36.4	68.5	145.5	151.6
AK4	"AK3, AK3L1"	ENSG00000162433	"Adenylate kinase 4"	P27144	1	65147549-65232145	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"kidney: 183.5;liver: 104.0"	"Cell type enhanced"	"Detected in many"		"Hepatocytes: 242.6;Proximal tubular cells: 595.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"classical monocyte: 3.1;myeloid DC: 2.7"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"Hep G2: 208.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA042753, HPA049461"	Enhanced		Supported	Mitochondria	"Intracellular and membrane"	NA	Yes		39000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 81: Kidney & Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Mitochondria		"HPA042753: AB_2678146, HPA049461: AB_2680776"	"unprognostic (3.73e-2)"	"prognostic unfavorable (4.17e-4)"	"unprognostic (2.25e-1)"	"unprognostic (3.05e-3)"	"unprognostic (1.48e-2)"	"prognostic unfavorable (8.83e-4)"	"unprognostic (1.16e-3)"	"unprognostic (3.89e-2)"	"unprognostic (4.03e-1)"	"unprognostic (5.39e-2)"	"prognostic unfavorable (4.34e-5)"	"unprognostic (6.71e-2)"	"prognostic unfavorable (4.36e-4)"	"prognostic unfavorable (4.87e-4)"	"unprognostic (2.69e-1)"	"unprognostic (7.07e-2)"	"unprognostic (7.57e-2)"	24.7	1.9	19.5	6.6	21.0	4.9	26.6	17.8	20.8	6.1	17.5	19.7	4.3	7.0	4.2	23.4	7.6	13.7	51.7	21.4	21.2	183.5	104.0	2.8	1.6	19.0	22.8	4.6	1.2	18.3	4.7	8.3	22.8	16.2	14.0	21.9	9.6	12.7	1.7	27.4	6.6	21.4	18.5	1.2	15.0	11.3	22.7	5.7	2.5	38.8	3.3	19.1	11.8	21.1	73.2	5.0	5.6	23.9	51.6	48.7	12.0	12.1	15.0	25.6	70.8	108.1	8.6	39.1	31.0	19.0	32.1	46.1	18.8	89.9	101.9	33.0	21.5	37.9	21.9	208.6	2.5	29.9	4.6	27.2	49.6	25.1	73.0	42.2	0.9	12.2	48.0	0.6	39.6	31.2	1.1	1.3	24.6	1.0	42.5	0.2	41.0	7.1	37.8	3.2	20.5	15.4	21.6	1.5	16.7	25.8	29.7	12.9	4.2	42.4	36.2	3.3	20.9	39.5	18.8	2.1	68.7	10.9	2.5	0.9	3.1	0.0	0.1	0.6	0.2	0.2	0.1	0.2	2.7	0.1	0.1	0.1	0.4	0.3	0.1	0.4	0.0	0.8	19.5	21.0	17.8	20.8	21.4	21.2	19.0	22.8	22.8	18.5	22.7	21.1	11.2	0.0	0.5	51.2	4.7	49.7	23.6	44.2	63.7	24.5	48.9	44.7	105.7	52.9	14.3	31.3	2.1	2.2	0.6	15.8	56.7	18.6	3.4	30.1	8.2	19.6	5.4	13.9	17.1	12.1	21.1	11.4	27.5	52.2	0.0	36.4	11.7	242.6	3.3	16.8	7.7	8.7	24.4	7.8	9.2	5.8	4.1	6.9	24.9	3.7	5.7	32.7	0.0	9.5	2.5	31.9	4.3	9.4	0.4	38.7	18.8	595.5	12.3	6.5	6.6	5.6	18.8	1.8	9.5	43.1	74.3	4.9	3.6	0.7	23.1	20.4
AK5		ENSG00000154027	"Adenylate kinase 5"	Q9Y6K8	1	77282019-77559966	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	6	"brain: 121.0"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 150.5;Excitatory neurons: 403.7;Inhibitory neurons: 167.3;Oligodendrocytes: 706.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"myeloid DC: 13.6;naive CD4 T-cell: 16.3"	"Group enriched"	"Detected in many"	12	"dendritic cells: 13.6;T-cells: 16.3"	"Cell line enhanced"	"Detected in many"		"ASC TERT1: 93.7;BJ: 67.8;fHDF/TERT166: 77.5;LHCN-M2: 189.9;U-2 OS: 58.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019128, HPA057255"	Enhanced		Supported	"Centriolar satellite,Cytosol"		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Cytosol	"Centriolar satellite"	"HPA019128: AB_1844682, HPA057255: AB_2683383"	"unprognostic (4.07e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.85e-2)"	"unprognostic (1.03e-1)"	"unprognostic (6.04e-2)"	"unprognostic (2.20e-1)"	"unprognostic (2.01e-2)"	"unprognostic (1.84e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.91e-2)"	"prognostic favorable (3.88e-4)"	"unprognostic (3.56e-3)"	"unprognostic (6.17e-4)"	"unprognostic (1.18e-1)"	"unprognostic (5.96e-2)"	"unprognostic (6.76e-2)"	1.0	1.6	75.9	1.5	101.2	3.9	18.9	19.4	115.0	1.3	0.8	2.6	1.0	0.7	0.6	1.0	1.0	1.0	1.0	121.0	31.5	1.4	0.1	0.4	2.3	27.2	30.2	0.5	1.6	0.7	3.4	1.2	25.6	2.3	1.0	3.0	3.0	2.1	0.3	2.0	1.0	0.8	31.0	2.1	2.4	9.4	31.7	0.8	1.1	0.8	1.5	0.7	0.7	81.1	0.2	3.6	2.9	0.1	34.8	93.7	1.2	67.8	14.4	10.8	4.6	0.5	1.7	0.6	0.5	77.5	4.4	0.4	0.2	0.0	5.5	2.6	0.7	0.5	1.2	0.4	1.8	0.6	0.2	11.6	0.5	2.1	4.3	37.9	31.5	0.3	0.9	0.7	189.9	0.7	0.0	0.6	3.9	18.4	24.5	1.7	7.1	1.6	29.3	1.1	15.3	3.5	0.2	0.2	4.4	0.3	0.3	0.5	7.9	26.1	58.4	1.6	2.2	15.2	14.7	0.3	5.2	3.5	9.8	1.2	0.8	0.1	3.8	0.2	0.5	0.9	3.6	1.9	13.6	0.9	16.3	9.1	0.6	0.2	0.2	1.5	1.7	2.3	75.9	101.2	19.4	115.0	121.0	31.5	27.2	30.2	25.6	31.0	31.7	81.1	0.7	0.0	0.0	10.7	0.4	0.3	0.4	0.0	1.2	1.3	54.0	27.3	1.1	0.0	0.0	1.8	0.0	1.9	5.6	0.3	7.9	0.3	150.5	1.1	0.1	1.3	12.0	0.8	403.7	0.6	56.3	1.5	1.1	1.7	0.0	0.0	0.4	0.0	2.4	13.5	167.3	0.3	0.0	0.0	0.6	29.2	1.2	0.4	3.6	41.2	1.9	0.0	47.4	60.8	706.6	0.1	1.1	0.7	0.1	2.9	0.0	7.8	0.0	0.3	0.0	1.2	6.3	10.2	91.0	0.0	0.3	2.9	4.2	0.1	0.2	0.1
AK6	CINAP	ENSG00000085231	"Adenylate kinase 6"	Q9Y3D8	5	69350984-69370013	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 185.9;Late spermatids: 275.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			"CAB005361, HPA070217"	Supported		Supported	"Nuclear speckles,Centrosome,Cytosol"		No	No			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 16: U-266 - Nucleosome"	"Cluster 25: Spermatids - Spermatogenesis"	"Nuclear speckles"	"Centrosome, Cytosol"	"CAB005361: AB_2302969, HPA070217: "	"unprognostic (5.47e-2)"	"unprognostic (1.54e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.58e-2)"	"unprognostic (8.73e-2)"	"unprognostic (4.09e-2)"	"prognostic unfavorable (9.54e-4)"	"unprognostic (1.79e-1)"	"unprognostic (3.41e-2)"	"unprognostic (6.21e-2)"	"unprognostic (2.55e-2)"	"unprognostic (2.25e-2)"	"unprognostic (1.14e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.84e-1)"	"unprognostic (2.22e-1)"	"unprognostic (2.55e-2)"	46.0	58.0	18.7	12.5	19.6	11.6	40.0	20.6	27.1	26.1	19.8	40.8	15.2	32.4	21.6	29.7	29.6	7.7	48.4	19.8	20.3	54.9	46.6	29.5	13.0	19.7	20.1	32.6	35.8	11.6	28.6	12.1	19.5	32.9	12.6	23.2	30.9	8.3	79.8	20.6	30.1	9.5	18.7	28.0	36.4	43.3	19.5	13.3	33.0	23.3	12.5	35.5	28.0	20.7	40.3	18.8	28.0	42.6	43.6	26.3	51.1	59.3	18.6	23.8	30.7	56.0	35.5	82.1	54.9	23.4	62.2	14.0	37.2	23.3	40.0	33.1	15.7	40.7	47.8	44.9	33.0	49.5	17.1	14.0	33.3	23.0	37.0	25.0	14.8	45.8	36.6	29.3	28.6	42.1	50.2	31.4	25.0	17.9	10.5	55.8	34.5	44.5	40.3	31.3	14.4	13.3	28.2	26.4	44.6	21.3	25.1	54.7	29.5	20.4	34.6	41.4	47.6	33.1	74.4	75.3	29.8	69.3	28.9	25.2	16.8	20.1	19.2	22.1	20.3	29.8	22.8	24.9	24.8	26.1	24.5	26.3	2.7	24.1	21.0	29.9	25.8	13.3	18.7	19.6	20.6	27.1	19.8	20.3	19.7	20.1	19.5	18.7	19.5	20.7	51.5	22.4	30.0	14.0	33.9	0.0	95.7	0.0	33.6	19.8	57.3	86.6	55.6	18.6	16.7	23.9	10.4	86.7	27.2	16.8	185.9	75.6	174.9	36.4	34.6	38.6	9.7	29.2	14.8	78.5	95.1	47.3	16.8	30.2	21.5	31.7	30.7	42.5	71.3	20.2	15.4	21.3	0.0	30.6	0.0	275.9	33.5	32.2	0.0	6.5	42.4	58.7	34.0	13.0	17.0	59.1	25.5	32.0	29.4	116.6	48.6	149.8	18.2	29.3	52.6	40.9	50.0	56.5	37.9	24.3	0.0	66.2	27.6	44.7	32.9	88.1
AK7	"CFAP75, FAP75, FLJ32864"	ENSG00000140057	"Adenylate kinase 7"	Q96M32	14	96392128-96489427	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cilium biogenesis/degradation"	"Kinase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"fallopian tube: 24.3"	"Group enriched"	"Detected in many"	4	"Endometrial ciliated cells: 97.9;Respiratory ciliated cells: 137.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	23	"basophil: 9.0"	"Lineage enriched"	"Detected in single"	29	"granulocytes: 9.0"	"Cell line enhanced"	"Detected in many"		"BEWO: 17.0;CAPAN-2: 15.1;MCF7: 49.5;REH: 35.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA003543	Enhanced					NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 42: Ciliated cells - Cilium & Cell projection"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 49: Ciliated cells - Cilium organization"			"HPA003543: AB_1078117"	"unprognostic (4.18e-3)"	"unprognostic (1.14e-1)"	"unprognostic (9.40e-3)"	"prognostic favorable (3.18e-4)"	"unprognostic (4.98e-5)"	"unprognostic (8.41e-2)"	"unprognostic (9.81e-3)"	"unprognostic (1.29e-1)"	"unprognostic (9.02e-2)"	"unprognostic (3.65e-4)"	"unprognostic (8.64e-2)"	"unprognostic (1.89e-1)"	"prognostic favorable (1.14e-4)"	"unprognostic (2.00e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.25e-3)"	0.7	2.6	2.0	0.6	3.1	1.5	1.4	1.1	1.7	1.7	13.2	2.1	1.9	2.1	3.9	1.5	24.3	2.6	0.7	2.2	5.2	4.5	1.6	4.2	0.6	6.9	9.4	0.4	2.2	6.9	5.1	0.5	5.6	0.9	1.6	3.0	1.0	1.3	0.3	6.1	1.2	1.1	4.4	3.3	2.8	7.6	5.0	0.5	2.7	0.0	0.4	0.5	1.0	4.2	0.2	4.9	2.0	1.5	0.8	2.6	17.0	0.3	0.6	0.3	0.3	0.5	15.1	0.4	0.3	0.0	0.3	1.9	4.7	0.2	0.1	2.2	0.4	0.4	2.4	0.2	0.8	0.1	0.3	0.2	0.6	2.5	0.1	0.8	0.2	1.4	0.2	0.3	0.3	49.5	0.3	0.3	0.8	2.2	1.0	35.2	0.3	0.4	7.6	0.3	3.1	6.7	1.9	0.6	0.1	1.8	4.2	0.2	0.1	0.4	0.2	0.6	0.2	0.6	2.3	0.2	0.2	0.0	0.7	9.0	0.1	0.1	0.1	0.0	0.1	0.1	0.1	0.3	0.0	0.2	0.1	0.1	0.3	0.2	0.2	0.0	0.0	0.1	2.0	3.1	1.1	1.7	2.2	5.2	6.9	9.4	5.6	4.4	5.0	4.2	1.6	6.4	4.1	0.7	0.8	1.8	0.9	3.6	1.8	0.2	0.9	0.3	0.4	4.3	12.3	7.3	2.1	0.7	0.1	1.4	3.9	3.2	18.7	97.9	1.7	1.9	1.2	6.9	2.0	1.1	1.7	0.8	5.1	11.6	0.0	0.1	0.7	2.4	0.2	0.0	2.4	0.3	4.1	0.3	0.4	4.1	0.0	0.5	1.8	0.0	0.0	0.6	0.0	0.5	3.7	0.5	0.1	0.0	0.0	0.5	1.0	3.4	137.1	1.8	0.0	0.4	1.6	25.4	9.1	0.7	3.0	2.9	0.2	1.5	1.2	0.6
AK8	"C9orf98, FLJ32704"	ENSG00000165695	"Adenylate kinase 8"	Q96MA6	9	132725578-132878777	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"epididymis: 19.3;fallopian tube: 25.8;testis: 15.9"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 102.3;Endometrial ciliated cells: 26.1;Late spermatids: 134.1;monocytes: 49.2;Respiratory ciliated cells: 36.7"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	30	"memory B-cell: 6.2;naive B-cell: 4.9;NK-cell: 3.1"	"Group enriched"	"Detected in many"	30	"B-cells: 6.2;NK-cells: 3.1"	"Cell line enhanced"	"Detected in some"		"MCF7: 3.1;RPTEC TERT1: 3.6;T-47d: 2.3"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA021443, HPA023894"	Enhanced					NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 42: Ciliated cells - Cilium & Cell projection"	"Cluster 6: T47d - Mammary gland"	"Cluster 3: Monocytes - Immune response regulation"			"HPA021443: AB_1845852, HPA023894: AB_1845854"	"unprognostic (4.14e-2)"	"unprognostic (1.20e-4)"	"unprognostic (1.31e-2)"	"unprognostic (1.70e-3)"	"unprognostic (2.16e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.14e-1)"	"unprognostic (3.18e-1)"	"unprognostic (3.43e-1)"	"unprognostic (1.71e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.42e-1)"	"prognostic favorable (1.61e-4)"	"unprognostic (9.89e-2)"	"unprognostic (3.22e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.43e-1)"	0.7	1.2	2.2	0.5	2.5	0.1	1.0	1.7	2.3	2.5	5.6	0.5	0.0	1.3	19.3	0.9	25.8	1.3	0.2	2.5	3.1	2.3	0.1	2.1	0.6	4.2	6.8	1.6	0.7	3.1	1.8	0.4	4.5	0.9	0.3	2.7	1.7	2.7	0.0	1.6	0.1	0.7	3.7	0.1	0.8	15.9	3.3	1.5	4.7	0.2	4.3	0.5	0.5	2.5	1.1	0.7	0.3	1.6	0.2	0.4	0.3	0.1	0.1	0.1	0.0	0.3	1.2	0.0	0.3	0.2	0.3	0.2	0.3	0.2	0.1	0.0	0.2	0.0	0.0	0.1	0.7	0.0	0.0	1.0	0.5	0.3	0.4	0.4	0.0	0.8	0.0	0.0	0.3	3.1	0.7	0.3	0.1	0.4	0.5	0.0	0.0	0.0	3.6	0.0	0.6	0.6	1.5	0.0	0.2	0.3	2.3	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.2	0.0	0.0	0.0	4.9	0.1	0.0	0.0	3.1	0.0	0.0	0.0	0.1	2.2	2.5	1.7	2.3	2.5	3.1	4.2	6.8	4.5	3.7	3.3	2.5	0.2	3.2	1.7	9.4	1.5	0.5	0.5	3.9	0.6	0.3	0.8	0.5	1.2	0.0	3.4	3.7	0.0	0.4	0.1	0.3	0.0	2.8	102.3	26.1	1.1	1.1	0.0	0.4	4.9	0.5	0.3	0.8	0.0	1.3	0.0	0.4	0.7	0.0	1.7	0.0	5.1	0.9	2.0	0.3	0.3	134.1	6.2	1.8	1.8	0.0	49.2	0.8	0.0	4.5	5.0	1.2	0.3	4.1	0.0	0.6	0.0	6.0	36.7	1.8	0.0	0.8	2.7	24.3	5.6	0.4	1.6	0.4	0.2	1.0	0.5	0.7
AK9	"AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954"	ENSG00000155085	"Adenylate kinase 9"	Q5TCS8	6	109492856-109691217	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	"Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Endometrial ciliated cells: 76.3;Respiratory ciliated cells: 152.0;Spermatocytes: 174.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in some"		"midbrain: 3.6"	"HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711"	Enhanced		Enhanced	"Nucleoplasm,Nuclear membrane"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 77: Retina - Visual perception"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 49: Ciliated cells - Cilium organization"	"Nucleoplasm, Nuclear membrane"		"HPA030804: AB_2673617, HPA030805: AB_2673618, HPA031779: AB_10603674, HPA031781: AB_2674044, HPA036324: AB_2675060, HPA036711: AB_2675265"	"unprognostic (9.68e-3)"	"unprognostic (2.15e-1)"	"unprognostic (1.66e-2)"	"unprognostic (2.36e-2)"	"unprognostic (3.42e-1)"	"unprognostic (7.28e-2)"	"unprognostic (1.41e-3)"	"unprognostic (6.76e-3)"	"unprognostic (1.89e-1)"	"unprognostic (3.50e-2)"	"unprognostic (1.67e-4)"	"unprognostic (2.58e-1)"	"unprognostic (2.98e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.30e-1)"	"unprognostic (8.39e-2)"	"unprognostic (5.56e-2)"	3.5	3.1	8.1	3.3	9.9	3.7	4.8	13.5	17.2	3.5	10.9	4.6	3.6	4.3	7.6	4.3	7.9	3.5	4.9	6.4	11.0	5.3	3.1	4.1	4.2	8.8	10.7	3.6	3.4	9.2	7.7	3.1	9.5	3.9	4.5	14.1	5.1	3.9	4.8	3.9	3.6	3.9	10.7	4.0	4.5	16.6	8.7	7.6	6.9	3.5	3.6	3.4	3.2	13.4	2.3	1.6	6.6	11.5	6.1	3.7	4.8	3.5	4.3	3.6	4.9	2.6	4.6	4.9	1.7	3.4	7.9	3.7	1.9	3.9	7.6	10.2	4.0	3.8	3.8	2.6	4.8	4.4	2.3	3.1	7.3	6.6	8.6	8.8	4.2	7.2	3.6	4.0	2.7	4.7	4.1	3.2	1.5	5.1	2.5	5.5	3.7	4.7	5.0	4.3	7.8	6.4	4.2	3.9	5.9	3.7	5.1	5.8	5.2	3.1	2.2	5.1	2.3	2.0	1.8	2.8	6.8	5.9	2.0	17.1	2.8	7.1	5.1	1.5	4.4	13.1	4.9	6.2	2.1	10.8	6.2	5.4	5.6	5.6	4.8	3.1	3.9	1.6	8.1	9.9	13.5	17.2	6.4	11.0	8.8	10.7	9.5	10.7	8.7	13.4	13.3	28.9	17.2	21.2	13.6	2.7	7.7	14.7	3.4	18.3	10.4	6.7	18.9	5.7	19.9	9.2	14.6	3.4	8.6	13.1	0.0	9.1	70.9	76.3	5.4	10.0	19.8	4.2	34.8	4.5	1.5	6.0	12.2	7.3	22.1	10.6	8.9	2.1	3.6	20.2	37.0	15.5	14.2	5.3	3.9	41.7	7.5	5.6	5.4	25.3	5.0	12.6	18.6	22.6	46.9	7.4	8.9	6.4	5.5	5.6	22.9	6.8	152.0	50.7	26.3	9.1	6.9	174.3	34.1	4.0	2.6	5.6	10.3	4.7	11.4	7.9
ALLC	ALC	ENSG00000151360	Allantoicase	Q8N6M5	2	3658200-3702671	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at transcript level"	"Tissue enriched"	"Detected in single"	17	"testis: 16.5"	"Cell type enriched"	"Detected in some"	4	"Early spermatids: 140.7"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	19	"U-266/84: 6.1"	"Not detected"	"Not detected"													NA	NA				"Cluster 83: Testis - Spermatogenesis"	"Cluster 16: U-266 - Nucleosome"	"Cluster 29: Early spermatids - Spermatogenesis"							"unprognostic (5.47e-2)"	"unprognostic (3.24e-2)"		"unprognostic (2.91e-3)"	"unprognostic (4.75e-1)"	"unprognostic (2.17e-1)"	"unprognostic (1.06e-1)"	"unprognostic (9.83e-3)"	"unprognostic (5.42e-2)"	"unprognostic (1.74e-4)"	"unprognostic (1.01e-2)"	"unprognostic (2.73e-1)"			0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.1	0.1	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.1	0.1	0.4	0.6	0.0	0.0	0.1	0.1	0.2	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	16.5	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	140.7	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.5	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	33.2	3.4	0.1	1.8	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	22.2	0.0	0.0	0.0	0.5	0.0	0.0	13.1	0.0	0.1	5.1	1.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0
AMPD1	"MAD, MADA"	ENSG00000116748	"Adenosine monophosphate deaminase 1"	P23109	1	114673090-114695618	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	23	"skeletal muscle: 559.2;tongue: 211.4"	"Group enriched"	"Detected in some"	6	"Plasma cells: 43.8;Skeletal myocytes: 13.3"	"Cancer enhanced"	"Detected in single"		"head and neck cancer: 0.8"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	29	"U-266/70: 8.7"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA026478, HPA028080"	Enhanced				"Intracellular and membrane"	NA	NA		38000	"Cluster 37: B-cells - Transcription"	"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 37: Myocytes - Muscle contraction"			"HPA026478: AB_10599969, HPA028080: AB_10600776"	"unprognostic (1.98e-3)"	"unprognostic (1.43e-3)"	"unprognostic (8.75e-3)"	"unprognostic (8.03e-2)"		"unprognostic (1.95e-2)"		"unprognostic (5.61e-3)"	"unprognostic (8.21e-2)"	"unprognostic (4.29e-3)"	"unprognostic (2.48e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.36e-5)"	"unprognostic (1.68e-1)"	"unprognostic (3.70e-1)"	"unprognostic (3.36e-1)"	"unprognostic (4.02e-1)"	0.1	0.1	0.0	0.5	0.0	0.3	3.0	0.0	0.0	0.2	0.0	5.6	16.4	0.2	0.0	5.8	0.4	0.2	0.1	0.0	0.0	0.0	0.1	0.7	0.5	0.0	0.0	1.0	0.1	0.3	0.0	0.0	0.0	3.5	5.5	0.0	4.4	0.9	559.2	0.0	7.5	0.1	0.0	1.6	3.7	0.1	0.0	0.4	0.1	211.4	2.9	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.7	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.7	0.5	0.0	0.0	0.0	0.0	0.1	0.1	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.6	0.0	0.1	0.1	0.0	0.0	0.6	0.0	0.0	0.1	0.0	0.2	0.0	0.0	0.4	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	1.5	0.0	0.0	1.8	1.9	0.0	0.0	0.0	3.0	4.2	0.0	0.0	0.0	43.8	0.0	0.0	0.0	0.0	0.0	0.0	13.3	0.2	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.1
AMPD2	SPG63	ENSG00000116337	"Adenosine monophosphate deaminase 2"	Q01433	1	109616104-109632051	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase	"Disease variant, Hereditary spastic paraplegia, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cone photoreceptor cells: 62.6;Horizontal cells: 52.2;Macrophages: 52.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 19.4;eosinophil: 19.2;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.1;non-classical monocyte: 44.6"	"Group enriched"	"Detected in all"	5	"dendritic cells: 18.9;granulocytes: 61.1;monocytes: 44.6"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA027137, HPA045760"	Approved		Enhanced	Cytosol		NA	NA		230000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 41: Macrophages - Immune response"	Cytosol		"HPA027137: AB_2672129, HPA045760: AB_2679443"	"unprognostic (2.78e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.43e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.25e-2)"	"unprognostic (3.91e-3)"	"unprognostic (1.71e-1)"	"unprognostic (4.02e-1)"	"unprognostic (1.23e-1)"	"unprognostic (8.10e-3)"	"unprognostic (1.50e-1)"	"prognostic unfavorable (3.78e-10)"	"unprognostic (9.16e-2)"	"unprognostic (2.03e-1)"	"unprognostic (1.35e-2)"	"unprognostic (1.60e-1)"	9.3	17.5	31.2	12.0	41.6	28.6	7.4	22.9	34.7	13.1	36.6	7.5	10.7	11.5	4.1	7.2	13.1	8.8	7.2	34.8	37.0	10.5	16.2	13.4	7.6	34.7	31.7	17.5	10.0	9.4	45.8	7.6	33.6	10.8	4.1	10.5	9.2	12.0	3.3	8.5	10.8	7.1	27.9	19.0	8.6	4.3	39.3	4.9	10.6	1.5	5.9	7.5	11.4	29.0	20.6	22.5	20.5	20.1	18.0	18.7	8.6	25.6	57.2	24.9	25.0	19.1	7.0	10.5	21.8	39.1	16.0	11.3	15.8	20.0	13.4	13.0	20.7	46.0	15.6	19.3	24.9	15.7	45.7	23.3	13.2	32.5	24.1	28.2	26.7	17.0	17.4	13.0	16.0	23.2	26.7	29.0	20.6	17.1	22.9	18.6	15.8	17.3	24.2	8.7	19.3	22.4	17.4	19.8	24.6	5.7	10.4	16.2	16.7	27.7	39.0	33.7	25.4	48.4	28.4	12.1	50.8	25.9	35.1	0.5	19.4	19.2	5.3	40.7	8.0	5.3	5.2	4.9	18.9	2.7	6.4	5.1	61.1	4.3	44.6	2.6	4.0	12.3	31.2	41.6	22.9	34.7	34.8	37.0	34.7	31.7	33.6	27.9	39.3	29.0	3.6	3.2	5.5	13.7	9.4	8.9	5.4	5.0	9.1	41.0	8.8	11.4	3.2	12.8	5.4	0.0	62.6	4.9	10.0	4.2	7.9	9.8	3.5	4.4	9.4	7.1	17.5	5.0	13.3	11.2	8.6	12.6	14.3	5.5	3.8	11.0	6.1	20.5	10.8	52.2	17.6	9.6	2.0	42.1	42.0	1.3	13.1	52.5	5.4	6.5	16.1	10.5	6.2	12.1	10.6	10.3	3.0	21.4	11.1	11.1	6.1	4.5	4.2	7.2	13.1	8.8	10.6	4.2	3.8	7.9	8.1	2.6	15.4	8.5	10.7	4.0
AMPD3		ENSG00000133805	"Adenosine monophosphate deaminase 3"	Q01432	11	10308313-10507579	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 62.9;skeletal muscle: 73.3"	"Cell type enhanced"	"Detected in many"		"Oligodendrocytes: 111.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 44.2;CAPAN-2: 34.6;HMC-1: 36.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038662, HPA047408"	Uncertain		Approved	"Nuclear membrane"		NA	NA		77000	"Cluster 49: Eosinophils - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	"Nuclear membrane"		"HPA038662: AB_2676136, HPA047408: AB_2680034"	"unprognostic (2.24e-1)"	"unprognostic (3.88e-3)"	"unprognostic (1.44e-2)"	"prognostic favorable (2.37e-4)"	"unprognostic (1.89e-2)"	"unprognostic (1.71e-3)"	"unprognostic (2.91e-3)"	"unprognostic (1.25e-1)"	"unprognostic (7.83e-2)"	"unprognostic (2.26e-1)"	"unprognostic (1.84e-2)"	"unprognostic (4.68e-1)"	"unprognostic (3.06e-2)"	"unprognostic (7.07e-2)"	"unprognostic (4.42e-2)"	"unprognostic (2.98e-1)"	"unprognostic (2.12e-2)"	4.2	19.6	10.8	20.7	22.5	62.9	3.0	19.1	15.3	6.0	10.8	4.9	6.5	4.2	4.0	7.6	11.1	6.4	2.9	10.4	15.9	7.8	1.8	6.9	17.6	21.1	20.5	2.6	3.3	24.1	18.2	4.1	20.5	7.4	6.6	7.5	6.4	3.5	73.3	15.6	7.8	4.4	14.0	12.1	6.7	1.8	21.4	13.9	3.6	9.3	20.3	9.7	7.9	30.2	14.1	2.0	0.5	0.2	7.1	5.0	0.8	12.4	44.2	3.0	3.1	6.9	34.6	5.1	1.2	5.7	11.9	8.6	0.2	11.8	8.8	12.7	0.5	12.5	1.8	1.0	2.4	17.2	36.0	18.5	17.9	6.0	7.7	7.5	1.4	8.3	19.4	5.3	10.1	0.5	10.2	22.3	1.6	1.1	12.2	3.7	15.9	18.2	0.6	11.5	5.1	2.6	2.7	0.4	0.8	1.0	0.4	5.8	3.4	13.7	0.2	9.6	0.5	4.8	2.9	5.5	15.7	16.9	0.3	9.5	6.4	19.4	2.2	3.9	5.4	7.7	3.3	2.6	4.2	5.3	3.6	2.5	8.4	3.8	1.7	2.7	2.1	2.8	10.8	22.5	19.1	15.3	10.4	15.9	21.1	20.5	20.5	14.0	21.4	30.2	0.5	0.0	3.9	5.2	14.3	12.5	10.6	8.1	4.0	23.6	1.6	1.8	6.3	5.7	9.8	14.7	2.1	0.9	1.6	1.9	17.6	2.9	7.3	14.0	1.7	1.6	10.2	20.2	11.9	1.6	1.5	8.1	3.1	2.9	12.0	0.9	1.1	0.7	14.5	0.0	7.0	3.9	20.3	15.2	7.6	20.6	0.9	18.3	3.6	28.1	14.0	6.5	1.0	5.0	111.8	6.3	3.0	0.0	1.7	26.5	4.9	0.8	24.2	1.3	0.0	12.3	1.9	0.4	0.6	2.2	12.5	1.2	6.6	0.3	2.2	16.8
APRT		ENSG00000198931	"Adenine phosphoribosyltransferase"	P07741	16	88809339-88811937	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Purine salvage"	"Glycosyltransferase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA026681	Approved		Approved	Nucleoplasm,Cytosol		NA	NA		1600000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 32: Non-specific - Translation"	"Nucleoplasm, Cytosol"		"HPA026681: AB_1844964"	"unprognostic (5.87e-2)"	"unprognostic (5.10e-2)"	"unprognostic (1.98e-1)"	"unprognostic (3.67e-2)"	"unprognostic (1.78e-1)"	"unprognostic (2.50e-3)"	"unprognostic (1.72e-3)"	"unprognostic (6.90e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.82e-1)"	"unprognostic (6.78e-2)"	"unprognostic (8.74e-2)"	"unprognostic (9.58e-3)"	"unprognostic (1.14e-1)"	"unprognostic (2.51e-1)"	"unprognostic (4.75e-2)"	"unprognostic (1.48e-2)"	118.5	161.2	30.1	73.6	30.1	103.1	112.3	32.0	39.5	109.6	39.3	121.0	72.2	81.2	25.5	231.1	87.6	31.4	70.2	29.9	32.0	128.7	190.4	85.8	83.8	32.9	31.3	73.3	169.4	66.1	64.9	37.0	32.1	113.6	40.2	5.1	119.8	44.6	62.7	240.1	106.8	29.8	33.7	128.6	131.8	35.2	35.1	77.2	96.9	23.8	64.5	95.7	153.7	35.7	157.9	228.3	44.9	200.4	54.2	106.0	232.2	117.1	105.0	136.0	52.6	237.6	189.0	145.5	221.9	68.4	65.0	165.3	74.8	195.4	27.5	102.9	417.7	124.3	106.5	253.0	168.1	87.4	97.7	113.1	207.6	109.0	139.4	63.7	172.6	244.6	266.6	107.9	71.4	586.0	242.1	254.7	169.4	169.5	288.8	259.2	69.2	351.5	156.3	107.0	218.2	132.4	223.5	130.7	131.2	41.9	427.9	171.1	111.4	122.5	104.9	99.5	118.0	205.9	186.5	408.8	179.9	228.4	110.5	77.7	544.5	202.8	474.5	473.5	631.7	501.1	612.0	510.3	562.4	517.3	557.8	475.3	31.8	501.8	322.1	731.6	551.8	998.0	30.1	30.1	32.0	39.5	29.9	32.0	32.9	31.3	32.1	33.7	35.1	35.7	146.5	115.4	147.4	5.9	247.0	319.0	320.0	375.7	207.7	19.9	346.2	479.7	46.9	230.2	206.8	92.0	6.2	265.0	262.3	273.1	406.9	404.3	11.8	124.6	180.3	163.1	210.8	150.6	5.1	442.6	401.5	170.3	192.7	148.4	131.9	154.9	147.8	309.6	348.0	15.2	4.4	386.4	160.7	253.9	336.1	35.4	239.9	214.6	297.1	3.7	449.4	78.7	355.3	2.5	7.2	392.3	228.3	135.4	171.6	404.3	349.2	647.9	125.5	20.4	39.5	135.6	186.5	18.4	126.9	358.8	494.7	172.7	285.7	339.5	426.7	385.2
ATIC	"AICARFT, IMPCHASE, PURH"	ENSG00000138363	"5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase"	P31939	2	215311956-215349773	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	"Hydrolase, Multifunctional enzyme, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013462, HPA021012"	Supported		Approved	"Plasma membrane,Cytosol"		NA	NA		3900000	"Cluster 44: Non-specific - Transcription"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Cytosol	"Plasma membrane"	"CAB013462: , HPA021012: AB_1845169"	"unprognostic (1.41e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.13e-2)"	"unprognostic (8.46e-2)"	"unprognostic (2.90e-1)"	"unprognostic (3.81e-2)"	"prognostic unfavorable (1.99e-7)"	"unprognostic (1.86e-2)"	"unprognostic (5.07e-2)"	"unprognostic (1.83e-1)"	"unprognostic (6.31e-3)"	"unprognostic (9.21e-2)"	"prognostic unfavorable (8.77e-4)"	"unprognostic (1.00e-1)"	"unprognostic (1.30e-1)"	"unprognostic (4.18e-2)"	"unprognostic (4.39e-3)"	24.8	26.0	19.8	31.7	23.4	26.4	33.9	21.4	23.5	22.2	18.8	36.4	32.0	30.0	20.3	19.4	29.4	20.4	21.3	19.6	21.5	32.7	34.6	18.0	44.9	20.5	21.5	32.0	26.2	29.6	18.6	37.3	23.3	28.7	47.5	19.1	18.8	38.4	43.2	23.8	27.2	37.0	21.0	27.6	24.5	20.1	22.9	41.8	22.5	25.4	51.8	29.1	17.6	27.5	102.2	133.8	85.1	144.0	112.5	113.2	40.6	105.4	91.9	117.4	134.9	278.6	157.3	149.6	122.8	110.0	164.5	106.7	187.8	157.0	169.5	113.4	189.3	179.1	108.7	271.5	145.4	226.1	92.0	98.4	119.8	154.7	188.5	82.0	79.7	144.5	237.0	124.4	166.3	178.7	203.4	112.1	330.3	167.4	84.9	185.8	117.3	133.4	126.4	146.5	129.3	87.8	84.3	103.1	124.3	189.2	169.7	82.9	70.2	96.0	101.2	127.3	65.8	160.3	195.7	300.1	85.6	124.5	146.8	12.6	16.4	0.4	34.6	23.5	59.1	56.6	49.0	53.8	36.3	39.9	50.0	46.9	1.8	55.4	21.1	31.7	50.2	29.0	19.8	23.4	21.4	23.5	19.6	21.5	20.5	21.5	23.3	21.0	22.9	27.5	7.2	12.8	19.3	18.6	34.7	15.0	28.2	55.0	30.7	10.0	18.2	16.1	21.1	28.6	33.3	23.9	4.2	171.4	23.3	17.6	27.4	45.2	1.1	20.7	28.2	6.1	19.2	32.2	15.4	49.3	166.3	25.3	22.4	20.8	25.3	32.9	5.3	22.2	52.4	10.1	15.4	33.8	26.4	14.4	10.8	1.7	23.9	20.2	30.2	2.8	26.1	21.3	26.8	16.6	25.7	32.4	28.5	34.3	36.3	24.0	18.8	52.7	27.3	14.7	26.3	19.2	29.0	3.3	43.8	24.6	8.5	95.4	29.8	40.7	58.4	18.1
CANT1	"SCAN-1, SHAPY"	ENSG00000171302	"Calcium activated nucleotidase 1"	Q8WVQ1	17	78991716-79009867	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"OE19: 445.4;T-47d: 282.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019627, HPA019639, HPA022818"	Enhanced		Supported	"Golgi apparatus"		NA	Yes		3300000	"Cluster 52: Eosinophils - Transcription"	"Cluster 37: Intestine - Unknown function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 27: Mucus-secreting cells - Mucin production"	"Golgi apparatus"		"HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971"	"unprognostic (1.98e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.50e-2)"	"unprognostic (5.36e-2)"	"unprognostic (2.13e-2)"	"unprognostic (2.21e-2)"	"prognostic unfavorable (1.41e-4)"	"prognostic unfavorable (2.90e-4)"	"unprognostic (1.76e-1)"	"unprognostic (9.00e-2)"	"unprognostic (3.30e-1)"	"unprognostic (2.49e-1)"	"prognostic unfavorable (6.21e-4)"	"unprognostic (7.04e-2)"	"unprognostic (5.06e-2)"	"unprognostic (1.16e-1)"	"unprognostic (7.23e-2)"	15.8	23.9	10.4	24.7	12.4	19.1	25.4	13.6	11.3	32.3	13.8	89.2	51.9	17.4	8.7	44.8	18.2	25.2	17.0	11.1	12.6	16.1	17.3	16.4	15.2	14.6	14.5	14.6	19.6	24.5	17.5	25.9	13.9	71.8	82.8	7.4	62.7	32.4	14.9	14.9	55.5	15.5	13.8	26.5	51.1	20.7	14.5	14.7	13.9	12.4	15.1	16.7	21.7	17.8	106.5	112.1	31.9	46.3	29.7	35.2	38.9	66.0	51.3	66.7	55.9	53.8	99.6	25.3	36.1	46.1	83.0	53.7	27.1	49.8	68.4	43.0	46.4	33.7	34.1	45.9	25.0	33.0	51.6	33.7	32.4	62.7	34.2	40.9	116.1	42.5	42.3	43.2	46.4	58.4	50.2	19.8	22.1	445.4	103.1	27.6	51.8	29.8	29.8	53.5	45.6	45.4	33.9	227.2	50.2	50.3	282.6	38.6	56.6	101.9	90.5	46.4	83.1	48.9	43.8	24.3	64.4	24.9	65.3	6.3	4.0	8.7	5.5	4.4	5.7	3.9	4.3	4.8	3.8	2.5	4.1	4.1	17.4	3.1	3.0	2.7	3.6	4.6	10.4	12.4	13.6	11.3	11.1	12.6	14.6	14.5	13.9	13.8	14.5	17.8	12.6	28.9	20.6	5.9	11.8	16.6	15.3	16.8	6.8	6.4	49.9	16.3	13.3	14.3	15.1	12.9	14.6	36.6	8.9	139.5	3.9	34.7	14.0	10.7	13.1	16.3	51.0	15.2	4.1	28.8	39.4	13.5	38.2	19.0	5.7	20.0	41.7	14.4	24.9	5.0	5.2	155.6	16.2	12.4	9.5	15.7	11.8	14.2	14.2	3.7	18.1	8.1	11.3	5.0	10.2	37.7	55.8	7.5	16.6	33.4	39.4	6.7	9.7	8.7	6.6	9.5	13.3	23.9	5.8	12.0	13.1	101.5	11.1	11.3	100.2	19.4
DCK		ENSG00000156136	"Deoxycytidine kinase"	P27707	4	70992538-71030914	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 105.8"	"Cell type enhanced"	"Detected in many"		"B-cells: 105.7;Erythroid cells: 284.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Daudi: 232.9;U-698: 191.8"	"Low region specificity"	"Detected in all"							"HPA059609, HPA062773"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 6: Erythroid cells - Oxygen transport"	Nucleoplasm		"HPA059609: AB_2684082, HPA062773: AB_2684865"	"unprognostic (9.16e-2)"	"unprognostic (2.44e-1)"	"unprognostic (5.24e-3)"	"unprognostic (4.77e-2)"	"unprognostic (3.95e-1)"	"unprognostic (6.45e-2)"	"prognostic unfavorable (6.90e-7)"	"unprognostic (3.04e-2)"	"unprognostic (7.19e-2)"	"unprognostic (8.28e-2)"	"unprognostic (4.51e-1)"	"unprognostic (1.33e-1)"	"unprognostic (3.37e-2)"	"unprognostic (4.47e-2)"	"unprognostic (6.82e-2)"	"unprognostic (1.33e-1)"	"unprognostic (2.27e-2)"	11.1	15.2	10.1	36.3	11.2	43.9	12.5	9.7	13.6	9.9	11.0	15.7	13.7	13.4	7.2	14.6	9.8	12.4	10.4	10.7	10.7	9.8	9.2	13.4	92.9	10.9	10.4	10.6	8.3	8.8	3.5	15.3	10.8	10.2	18.9	17.1	7.7	7.1	9.5	14.7	15.9	13.9	11.4	32.3	14.2	9.0	9.7	105.8	15.7	12.1	79.6	14.2	6.1	13.4	25.8	17.2	38.5	23.9	12.4	20.4	21.0	65.3	25.6	53.3	43.6	11.3	56.1	232.9	24.7	28.3	31.0	14.8	34.6	21.4	71.0	43.5	16.2	46.6	18.6	20.5	11.8	95.8	58.5	11.2	25.5	32.2	19.5	26.0	31.0	64.4	19.0	93.2	62.0	15.5	126.6	39.5	17.2	45.6	15.6	96.0	74.0	18.6	26.6	18.8	35.1	31.8	24.9	49.6	29.7	17.4	22.3	54.3	22.0	60.1	41.8	47.6	37.1	31.7	21.2	191.8	40.7	60.0	45.0	25.6	17.2	28.9	24.2	20.5	32.0	44.5	33.0	30.6	23.8	41.1	34.2	34.2	8.1	34.4	21.0	63.6	41.2	45.1	10.1	11.2	9.7	13.6	10.7	10.7	10.9	10.4	10.8	11.4	9.7	13.4	16.4	0.0	8.6	6.8	105.7	43.0	10.1	11.9	27.9	16.1	10.4	5.2	6.5	7.2	7.5	12.9	6.2	11.9	97.7	10.4	29.4	19.2	0.7	5.9	7.0	16.3	21.0	284.8	17.1	6.2	19.3	11.0	8.6	7.4	22.9	7.5	22.9	7.2	38.2	18.5	21.0	16.4	22.4	63.2	74.5	2.3	8.4	56.0	46.2	18.7	61.4	15.8	84.5	8.0	11.1	10.5	8.0	10.1	24.6	11.6	7.1	10.0	4.7	10.7	6.6	9.3	15.9	52.0	33.9	28.0	43.3	4.5	62.4	4.8	16.5	8.4
DGUOK	dGK	ENSG00000114956	"Deoxyguanosine kinase"	Q16854	2	73926826-73958961	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase"	"Disease variant, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034766, HPA057246"	Approved					NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"			"HPA034766: AB_10669850, HPA057246: AB_2683381"	"unprognostic (3.40e-1)"	"unprognostic (2.43e-1)"	"unprognostic (1.45e-2)"	"unprognostic (2.94e-2)"	"unprognostic (1.20e-1)"	"unprognostic (4.17e-2)"	"unprognostic (2.14e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.10e-3)"	"unprognostic (5.07e-2)"	"unprognostic (1.41e-1)"	"unprognostic (9.84e-2)"	"prognostic unfavorable (8.69e-7)"	"unprognostic (3.86e-1)"	"unprognostic (2.21e-2)"	"unprognostic (5.98e-2)"	"prognostic favorable (7.47e-4)"	20.8	30.0	37.1	20.3	39.2	27.1	28.1	36.5	48.4	23.0	36.8	25.0	17.7	23.1	34.4	21.8	31.3	19.4	23.0	38.5	42.8	24.6	30.5	17.7	36.8	37.9	37.7	30.0	16.3	11.0	41.3	21.5	39.1	24.5	29.1	34.5	19.8	22.5	17.1	26.5	20.2	21.9	37.9	25.9	21.0	32.8	38.8	36.3	22.6	17.7	40.9	22.2	20.9	38.8	45.1	72.5	74.4	67.9	47.8	53.8	37.1	29.3	56.0	66.7	61.1	91.2	51.5	83.0	27.4	42.1	74.1	34.7	85.4	57.1	79.3	47.1	53.6	65.8	25.4	107.5	70.5	62.1	66.0	49.7	51.3	50.4	58.9	48.6	48.3	91.4	67.2	37.0	78.8	54.4	59.6	101.2	76.7	60.5	53.9	73.8	73.1	59.7	55.8	49.6	85.0	82.6	27.9	28.2	77.1	35.5	34.0	34.8	45.3	43.3	68.8	37.8	52.6	32.3	31.4	86.1	62.2	65.9	95.1	129.8	70.9	138.7	62.3	87.3	72.4	108.5	77.0	69.6	81.6	114.5	98.6	79.6	56.4	79.4	84.7	91.3	79.9	91.3	37.1	39.2	36.5	48.4	38.5	42.8	37.9	37.7	39.1	37.9	38.8	38.8	72.5	32.1	42.8	14.7	103.4	74.2	138.7	249.6	88.2	52.3	85.0	128.1	19.1	78.6	108.6	60.7	6.2	159.4	89.7	58.9	84.1	102.6	12.3	82.3	69.1	74.1	113.1	67.1	17.5	149.1	165.4	88.3	40.2	82.6	57.6	87.4	76.1	69.9	90.9	52.2	21.1	100.1	158.7	88.3	112.3	15.1	93.5	80.2	110.3	15.9	151.9	89.5	118.4	12.5	27.2	173.0	88.1	86.9	70.2	146.2	88.2	119.7	87.2	40.4	92.1	55.3	89.3	105.3	129.4	88.3	83.3	124.5	101.4	124.5	104.9	142.9
ENTPD1	"ATPDase, CD39, NTPDase-1, SPG64"	ENSG00000138185	"Ectonucleoside triphosphate diphosphohydrolase 1"	P49961	10	95711779-95877266	"CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		Hydrolase	"Disease variant, Hereditary spastic paraplegia, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 74.1;Kupffer cells: 110.4;Langerhans cells: 161.3;Microglial cells: 217.4;monocytes: 112.2;Plasma cells: 80.1"	"Cancer enhanced"	"Detected in all"		"thyroid cancer: 17.9"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 102.2"	"Group enriched"	"Detected in all"	4	"dendritic cells: 31.9;granulocytes: 102.2;monocytes: 41.0"	"Group enriched"	"Detected in many"	7	"HDLM-2: 147.5;Karpas-707: 135.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002494, HPA014067, CAB079986"	Enhanced		Uncertain	Microtubules		NA	NA		19000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 41: Macrophages - Immune response"	Microtubules		"CAB002494: AB_563557, CAB079986: , HPA014067: AB_1848178"	"unprognostic (1.14e-1)"	"unprognostic (1.01e-2)"	"unprognostic (3.11e-1)"	"unprognostic (5.67e-2)"	"unprognostic (9.68e-3)"	"unprognostic (3.45e-3)"	"unprognostic (6.31e-2)"	"unprognostic (5.26e-3)"	"unprognostic (2.73e-1)"	"unprognostic (1.28e-2)"	"unprognostic (6.40e-2)"	"unprognostic (1.41e-1)"	"prognostic unfavorable (5.33e-5)"	"unprognostic (9.79e-2)"	"unprognostic (2.30e-1)"	"prognostic favorable (7.89e-4)"	"unprognostic (5.09e-2)"	11.8	8.3	5.9	24.7	5.5	27.5	10.8	5.0	6.3	17.5	5.0	14.3	9.3	28.0	19.3	19.2	14.0	27.7	8.5	5.3	6.3	7.6	5.4	16.1	20.2	7.1	6.5	5.5	2.8	3.4	3.9	11.4	7.7	11.2	12.8	6.8	6.0	18.1	4.0	6.3	11.7	49.7	6.2	21.5	7.3	4.5	7.5	6.8	20.0	8.7	25.6	30.6	11.0	6.3	1.4	2.7	5.4	7.1	0.1	0.1	5.0	4.5	1.2	0.0	0.0	4.0	1.6	8.2	3.1	0.0	5.3	2.2	0.0	0.0	0.0	147.5	5.2	7.2	4.0	4.3	0.0	12.5	4.1	0.1	0.0	0.6	0.0	2.4	18.2	2.0	5.3	135.4	0.1	4.4	4.7	5.8	5.9	3.6	2.8	15.3	2.4	4.4	1.7	2.2	5.1	6.2	3.6	3.7	3.9	3.6	5.5	5.9	3.9	3.9	2.8	3.8	5.3	21.6	7.2	0.6	4.3	13.9	2.7	0.7	41.0	102.2	0.6	27.2	1.1	13.7	1.6	1.1	31.9	11.4	0.6	0.6	49.4	1.5	6.7	2.1	13.1	15.5	5.9	5.5	5.0	6.3	5.3	6.3	7.1	6.5	7.7	6.2	7.5	6.3	19.6	0.0	1.1	74.1	40.9	8.9	0.3	0.0	0.6	1.4	0.8	1.5	10.1	0.0	0.7	1.8	2.1	0.6	3.7	0.3	1.9	0.0	10.3	0.6	3.6	60.6	0.0	4.4	2.8	2.0	1.9	15.7	6.1	0.6	3.8	0.3	31.4	0.8	26.6	0.0	5.2	0.1	0.0	110.4	161.3	7.3	0.6	62.1	16.0	217.4	112.2	0.4	0.0	20.6	5.0	0.2	1.2	3.0	80.1	0.5	0.1	0.3	0.8	0.8	6.6	1.0	22.7	10.1	4.4	0.8	11.2	15.7	26.9	15.1	1.0	0.5
ENTPD2	"CD39L1, NTPDase-2"	ENSG00000054179	"Ectonucleoside triphosphate diphosphohydrolase 2"	Q9Y5L3	9	137048107-137054061	"Metabolic proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 31.7"	"Cell type enhanced"	"Detected in many"		"Leydig cells: 192.3;Paneth cells: 35.5;Peritubular cells: 96.7;Proximal enterocytes: 61.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"Hep G2: 24.3;hTCEpi: 12.7;MCF7: 16.7;OE19: 26.6;SK-BR-3: 21.6;T-47d: 23.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA017676	Approved					NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 45: Intestine - Brush border"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 45: Enterocytes - Digestion"			"HPA017676: AB_1848179"	"unprognostic (1.64e-1)"	"unprognostic (3.35e-2)"	"unprognostic (1.76e-1)"	"unprognostic (3.33e-2)"	"unprognostic (2.15e-3)"	"unprognostic (1.07e-1)"	"prognostic unfavorable (2.48e-5)"	"unprognostic (2.71e-2)"	"unprognostic (4.97e-2)"	"unprognostic (3.23e-1)"	"unprognostic (2.99e-1)"	"unprognostic (1.89e-1)"	"prognostic favorable (3.51e-6)"	"prognostic favorable (1.38e-4)"	"unprognostic (2.51e-1)"	"unprognostic (8.43e-2)"	"unprognostic (1.12e-3)"	1.0	0.8	17.5	0.9	13.0	0.2	5.0	13.3	14.8	5.9	4.3	6.8	12.2	1.8	1.6	3.3	6.1	4.5	3.4	12.5	28.1	4.7	0.9	0.4	0.1	15.9	31.7	0.7	1.8	0.9	3.0	0.7	17.1	7.3	3.8	1.0	5.5	1.6	2.0	10.2	7.8	1.0	16.7	0.1	6.1	3.5	26.4	0.2	0.6	3.4	0.3	1.2	3.6	14.5	6.5	1.7	0.0	0.1	0.1	0.0	3.9	0.0	0.0	0.0	0.0	1.2	1.9	0.0	1.4	0.0	0.0	5.1	0.5	3.7	0.0	0.0	0.2	0.0	0.8	24.3	0.0	0.0	0.3	0.0	12.7	0.0	3.3	0.3	0.0	0.0	0.0	0.0	0.0	16.7	0.0	0.0	0.0	26.6	3.6	0.0	1.1	2.5	2.8	0.6	3.5	0.1	0.3	21.6	0.0	0.1	23.4	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	17.5	13.0	13.3	14.8	12.5	28.1	15.9	31.7	17.1	16.7	26.4	14.5	1.1	0.0	0.0	19.2	0.5	1.7	1.9	2.8	4.0	0.2	8.0	13.2	0.5	11.5	1.8	0.0	0.0	0.3	0.0	26.2	0.0	6.2	1.4	12.1	1.5	1.2	25.2	0.0	0.2	4.3	1.1	1.5	5.1	2.8	0.0	0.0	0.4	1.1	0.2	0.0	0.1	9.4	6.1	0.0	0.0	6.2	192.3	0.3	5.4	1.9	0.6	6.8	0.0	0.5	0.1	6.0	35.5	96.7	0.0	4.4	61.8	8.6	3.2	0.1	0.0	0.4	4.1	1.2	4.4	1.8	1.4	1.0	0.2	0.0	16.0	1.5
ENTPD3	"CD39L3, HB6, NTPDase-3"	ENSG00000168032	"Ectonucleoside triphosphate diphosphohydrolase 3"	O75355	3	40387184-40428744	"Enzymes, Metabolic proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 20.8;cervix: 21.3;salivary gland: 22.4"	"Cell type enriched"	"Detected in many"	4	"Inhibitory neurons: 92.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	7	"plasmacytoid DC: 3.5"	"Lineage enriched"	"Detected in single"	7	"dendritic cells: 3.5"	"Cell line enhanced"	"Detected in some"		"HaCaT: 3.6;HBEC3-KT: 13.0;hTCEpi: 8.4;RT4: 18.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 24: Salivary gland - Salivary secretion"	"Cluster 15: RT4 - Unknown function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"				"unprognostic (1.00e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.75e-2)"	"unprognostic (9.84e-3)"	"unprognostic (2.27e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.18e-2)"	"unprognostic (8.40e-2)"	"unprognostic (9.88e-3)"	"unprognostic (4.72e-2)"	"unprognostic (2.08e-1)"	"unprognostic (3.25e-1)"	"unprognostic (6.53e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.23e-1)"	4.2	1.3	3.4	1.1	20.8	0.1	2.4	2.0	6.5	21.3	0.8	3.5	1.3	3.1	2.4	6.5	0.9	2.0	0.6	4.5	4.5	2.6	0.1	3.9	0.4	6.2	4.0	1.7	15.8	0.5	2.9	0.5	6.1	3.4	2.8	2.6	22.4	4.0	1.2	2.9	1.4	1.9	2.2	4.2	6.8	0.5	5.3	0.9	5.5	2.5	1.7	13.0	3.6	4.7	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.1	3.6	0.0	13.0	0.3	0.4	0.4	0.5	0.2	0.0	0.0	0.0	0.0	0.1	8.4	0.0	0.0	0.0	0.0	0.4	0.0	0.1	0.0	0.5	0.0	0.1	0.1	0.2	1.0	0.0	0.0	0.0	1.5	18.4	1.8	0.2	0.4	1.1	0.2	0.3	0.6	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.3	0.1	0.5	0.1	0.0	0.5	0.0	0.0	0.1	0.1	0.2	0.0	0.0	0.1	0.0	0.1	0.2	0.2	0.0	0.4	0.0	3.5	0.2	0.0	3.4	20.8	2.0	6.5	4.5	4.5	6.2	4.0	6.1	2.2	5.3	4.7	5.5	3.2	4.2	4.9	0.2	2.3	1.3	2.3	8.0	0.7	6.1	0.3	0.5	0.0	5.1	0.0	0.0	0.0	1.3	1.0	0.0	2.7	0.4	7.6	2.5	0.7	2.4	0.0	22.6	22.5	0.0	0.4	2.6	14.9	0.0	0.0	0.0	0.0	0.1	0.0	92.6	0.1	0.0	0.0	0.8	0.0	0.3	0.3	0.0	1.9	0.0	3.7	0.0	7.1	5.9	6.9	0.0	0.7	0.1	1.4	0.0	0.0	1.9	0.8	19.7	0.6	19.9	0.2	0.1	14.5	2.3	0.0	0.2	0.1	0.2	4.7
ENTPD4	"KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase"	ENSG00000197217	"Ectonucleoside triphosphate diphosphohydrolase 4"	Q9Y227	8	23385783-23457695	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA017655	Supported		Approved	Vesicles		NA	NA		82000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 12: NES - Nervous system development"	"Cluster 52: Non-specific - Transcription"	Vesicles		"HPA017655: AB_1848181"	"unprognostic (2.83e-2)"	"unprognostic (1.50e-2)"	"unprognostic (1.23e-3)"	"unprognostic (1.38e-1)"	"unprognostic (5.06e-2)"	"unprognostic (7.86e-3)"	"unprognostic (2.00e-2)"	"unprognostic (2.99e-3)"	"unprognostic (2.07e-2)"	"unprognostic (8.74e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.20e-1)"	"unprognostic (4.55e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.11e-1)"	"unprognostic (6.62e-2)"	"unprognostic (3.72e-2)"	16.3	11.5	8.6	24.2	10.5	30.5	14.8	11.1	16.2	17.0	8.1	19.8	18.1	16.8	17.3	12.6	13.7	14.6	21.2	10.8	12.3	12.2	13.7	20.0	29.3	13.1	9.2	13.5	21.4	27.2	18.3	17.2	12.8	16.8	20.3	32.7	22.0	13.4	15.2	12.4	26.2	16.5	7.6	25.4	20.3	19.9	12.5	14.5	14.7	15.9	29.8	16.7	16.6	11.6	20.8	28.7	34.0	23.5	29.0	36.8	35.0	33.1	30.4	21.3	33.2	40.3	26.4	35.5	22.9	32.8	32.9	24.5	15.8	29.0	40.3	8.6	11.5	18.4	18.1	14.2	23.7	9.8	34.8	22.8	34.7	28.4	29.9	51.9	31.2	26.7	13.2	30.6	36.4	9.3	14.8	11.9	20.1	26.2	10.2	14.3	34.6	10.8	27.0	24.1	27.2	26.6	12.0	17.0	23.7	67.0	12.9	13.6	38.6	39.1	38.3	43.7	24.1	24.7	11.5	45.5	51.3	11.5	39.4	17.0	5.7	13.4	7.4	8.6	8.8	8.7	7.3	8.1	7.5	6.5	9.2	7.3	14.4	4.8	7.0	6.8	6.3	6.9	8.6	10.5	11.1	16.2	10.8	12.3	13.1	9.2	12.8	7.6	12.5	11.6	15.9	19.2	34.5	10.7	25.8	6.5	12.0	17.6	8.6	32.1	11.4	8.6	24.6	7.2	27.3	14.7	14.6	16.1	33.4	25.1	0.0	15.6	8.6	13.6	21.6	15.8	17.3	10.3	31.4	16.9	16.9	16.9	23.9	23.9	17.7	18.9	12.1	11.5	12.3	47.1	37.4	19.7	20.3	14.2	15.5	19.2	7.2	18.2	12.4	19.7	19.4	15.2	18.6	23.1	23.1	21.8	13.3	8.6	46.9	18.9	18.8	5.0	15.0	35.9	13.1	14.3	14.6	21.5	22.8	9.5	5.5	20.2	21.3	11.7	12.4	18.9
ENTPD5	"CD39L4, NTPDase-5, PCPH"	ENSG00000187097	"Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)"	O75356	14	73958010-74019399	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"		Hydrolase	Proto-oncogene	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"intestine: 107.2;kidney: 95.2;liver: 263.7"	"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0"	"Group enriched"	"Detected in all"	5	"liver cancer: 18.2;prostate cancer: 39.9"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"basophil: 18.3;eosinophil: 9.4"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 18.3"	"Cell line enhanced"	"Detected in all"		"RT4: 57.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002927	Enhanced				"Secreted to blood"	NA	NA		5900000	"Cluster 46: Basophils - DNA binding"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 15: RT4 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"			"HPA002927: AB_1078744"	"unprognostic (4.19e-1)"	"unprognostic (9.63e-3)"	"unprognostic (3.11e-2)"	"unprognostic (2.06e-2)"	"unprognostic (1.98e-1)"	"unprognostic (3.87e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.19e-1)"	"unprognostic (3.34e-1)"	"unprognostic (6.01e-2)"	"unprognostic (6.20e-2)"	"unprognostic (2.55e-1)"	"prognostic favorable (3.95e-5)"	"unprognostic (1.25e-1)"	"unprognostic (5.06e-2)"	"unprognostic (1.76e-1)"	"unprognostic (6.92e-3)"	8.2	7.7	5.0	11.4	7.3	8.0	12.4	7.1	6.7	7.3	7.1	94.6	72.1	6.3	7.7	11.3	5.7	12.1	7.7	5.1	6.3	95.2	263.7	6.5	5.5	7.6	7.3	6.7	4.9	7.7	5.0	5.6	7.8	37.7	107.2	9.4	10.7	4.4	15.0	8.1	68.4	9.7	6.5	6.0	42.3	8.6	7.3	4.6	6.1	9.1	5.6	16.9	7.2	9.0	9.5	7.8	8.2	15.1	16.5	15.5	9.4	9.6	7.9	6.4	7.1	5.6	10.9	10.6	4.7	12.8	6.0	10.8	8.5	14.1	7.2	8.8	4.0	7.9	5.7	30.9	15.5	4.7	8.8	12.9	14.0	8.7	18.2	8.8	13.1	17.1	8.8	15.4	9.7	13.6	5.4	5.6	2.5	8.5	15.7	6.0	8.0	5.2	11.4	57.1	5.8	6.0	16.6	12.9	9.2	6.4	18.7	4.1	10.8	12.6	12.7	7.5	7.2	10.1	16.9	8.3	8.0	8.8	11.5	18.3	1.2	9.4	2.5	2.3	1.3	1.4	1.3	1.8	1.7	1.5	2.1	2.1	0.1	0.5	1.4	0.9	1.6	1.3	5.0	7.3	7.1	6.7	5.1	6.3	7.6	7.3	7.8	6.5	7.3	9.0	8.0	16.0	6.7	8.1	4.9	3.7	6.2	8.9	5.2	6.6	15.0	7.9	5.2	10.0	11.3	7.3	4.2	8.2	4.3	209.3	25.4	6.9	19.5	10.0	13.6	7.0	16.2	36.6	5.9	12.9	6.7	7.9	23.0	25.8	1.3	9.6	9.7	134.8	6.2	10.1	8.2	77.1	14.2	9.7	1.9	12.7	2.8	5.2	5.4	11.2	5.4	4.9	8.2	2.0	11.3	9.1	58.4	5.7	3.6	28.5	87.0	63.1	6.4	12.2	13.1	6.0	5.9	27.2	19.1	8.5	3.4	3.3	4.9	10.3	60.9	39.0
ENTPD6	"CD39L2, dJ738P15.3, IL6ST2, NTPDase-6"	ENSG00000197586	"Ectonucleoside triphosphate diphosphohydrolase 6"	O75354	20	25195693-25228075	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-MEL-30: 289.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015491, HPA069555"	Approved		Supported	"Golgi apparatus"	"Secreted to blood"	NA	NA		41000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 22: Non-specific - Unknown function"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Golgi apparatus"		"HPA015491: AB_2669200, HPA069555: AB_2686152"	"unprognostic (3.24e-1)"	"unprognostic (1.27e-2)"	"unprognostic (5.91e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.76e-1)"	"unprognostic (4.44e-1)"	"unprognostic (2.10e-3)"	"unprognostic (7.41e-3)"	"unprognostic (2.74e-3)"	"unprognostic (1.17e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.03e-1)"	"unprognostic (8.14e-3)"	"unprognostic (1.78e-2)"	"unprognostic (2.74e-1)"	"unprognostic (4.86e-2)"	"unprognostic (4.48e-2)"	24.8	55.4	54.3	22.8	64.0	15.2	27.7	39.7	65.9	22.9	26.5	61.0	60.0	21.8	18.4	25.3	23.2	26.5	75.9	56.0	49.8	40.4	38.9	25.4	16.1	29.6	32.2	36.2	49.6	23.5	60.0	25.2	45.2	55.7	44.9	15.7	71.2	17.2	38.7	19.4	63.0	18.6	25.7	19.8	47.2	36.3	48.5	29.8	28.8	21.9	13.0	24.5	21.8	38.9	78.8	122.8	32.9	64.0	41.0	50.8	70.8	63.0	45.0	54.0	48.3	65.5	60.0	47.6	91.4	60.9	104.7	100.3	40.1	96.2	35.5	29.2	36.2	38.3	18.2	150.4	60.7	52.7	57.3	47.4	53.1	67.7	51.4	39.4	43.7	46.1	51.5	78.8	40.0	75.6	49.2	32.6	20.8	63.9	96.0	27.1	102.9	108.4	67.8	46.3	52.0	26.7	17.7	105.1	289.4	29.6	75.3	43.4	48.6	61.9	63.7	51.6	75.7	50.5	43.8	21.0	44.5	34.1	116.3	0.1	25.2	4.9	18.8	17.0	25.6	8.7	16.5	15.0	26.4	11.0	16.9	15.5	1.1	14.1	7.6	18.5	17.2	22.1	54.3	64.0	39.7	65.9	56.0	49.8	29.6	32.2	45.2	25.7	48.5	38.9	6.4	19.2	28.5	12.4	9.9	9.8	16.2	23.6	6.2	19.2	25.8	21.8	5.8	25.8	14.8	18.4	10.4	63.2	11.0	81.4	9.8	42.5	22.1	10.5	7.6	7.6	34.0	4.2	18.6	40.1	21.7	12.8	52.5	15.4	3.8	65.2	14.3	15.0	26.7	25.2	19.4	57.5	26.4	17.7	17.4	65.2	20.5	17.6	10.6	11.2	16.0	4.2	10.3	13.0	9.2	33.8	59.8	42.2	16.5	27.9	68.4	13.5	10.7	9.1	6.6	6.3	9.6	3.0	8.8	8.6	6.0	59.8	12.0	25.8	72.6	12.1
ENTPD8	"NTPDase-8, UNQ2492"	ENSG00000188833	"Ectonucleoside triphosphate diphosphohydrolase 8"	Q5MY95	9	137434364-137441816	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"intestine: 27.6;liver: 14.5"	"Group enriched"	"Detected in some"	5	"Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA021509	Enhanced		Approved	Nucleoplasm,Vesicles,Cytosol		NA	NA				"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Nucleoplasm, Cytosol"	Vesicles	"HPA021509: AB_1848185"	"unprognostic (3.85e-2)"	"unprognostic (8.33e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.40e-1)"	"unprognostic (6.46e-3)"	"unprognostic (8.70e-2)"	"unprognostic (3.87e-2)"	"unprognostic (8.48e-2)"	"unprognostic (1.69e-1)"	"unprognostic (2.34e-2)"	"unprognostic (1.08e-5)"	"prognostic favorable (7.17e-4)"	"unprognostic (2.17e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.78e-1)"	0.0	0.0	0.0	1.4	0.0	0.4	0.4	0.2	0.2	0.6	0.0	21.3	27.6	0.1	0.0	0.3	0.7	3.7	0.0	0.0	0.0	3.1	14.5	0.1	0.1	0.2	0.1	0.1	3.1	0.1	5.1	0.1	0.0	0.4	11.2	0.0	6.3	0.2	0.0	0.1	27.2	0.1	0.0	0.2	8.9	0.5	0.0	0.3	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.1	1.1	5.0	0.0	0.3	0.0	0.4	0.1	0.0	0.0	0.0	1.0	0.1	0.0	0.4	0.2	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.3	0.2	0.0	0.0	0.0	0.0	1.0	0.0	0.1	0.0	1.7	0.2	0.0	0.0	5.3	0.7	0.0	0.2	0.5	0.1	0.0	0.1	0.4	2.8	0.1	0.0	0.0	1.2	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.3	0.2	0.0	0.0	1.7	1.5	0.4	11.5	0.3	20.2	0.0	0.0	0.1	194.5	0.0	1.3	0.0	3.0	0.4	0.1	3.6	0.0	0.0	7.5	0.2	0.1	31.6	4.7	0.0	0.1	0.4	10.1	0.1	0.0	0.0	181.0	8.2	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	174.3	0.0	0.2	0.6	167.3	5.9	1.0	0.0	0.0	0.0	0.1	0.0	0.7	0.0	0.0	0.3	0.3	0.1	15.6	1.7
EPX	"EPO, EPP, EPX-PEN"	ENSG00000121053	"Eosinophil peroxidase"	P11678	17	58192726-58205174	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	17	"bone marrow: 33.7"	"Cell type enhanced"	"Detected in some"		"Excitatory neurons: 1.5;Inhibitory neurons: 1.2;Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	23	"eosinophil: 2.2"	"Lineage enriched"	"Detected in single"	23	"granulocytes: 2.2"	"Cell line enriched"	"Detected in some"	68	"NB-4: 248.2"	"Low region specificity"	"Detected in some"			"Not detected"	"Not detected"			HPA076792	Enhanced					NA	NA			"Cluster 49: Eosinophils - Unknown function"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 24: NB-4 - Immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"			"HPA076792: "	"unprognostic (5.67e-2)"	"unprognostic (1.73e-2)"	"unprognostic (3.36e-2)"	"unprognostic (3.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (1.34e-3)"	"unprognostic (4.83e-1)"	"unprognostic (3.16e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.52e-2)"	"unprognostic (1.71e-4)"	"unprognostic (7.38e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.02e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.73e-1)"	0.0	0.1	0.0	0.2	0.2	33.7	0.0	0.3	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.2	0.4	0.4	0.0	0.0	0.2	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.5	0.3	0.0	0.1	0.5	0.1	0.0	0.0	1.3	0.1	0.1	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.1	0.0	0.0	0.0	3.6	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.1	0.2	248.2	0.0	0.0	0.0	0.3	0.1	0.1	0.0	0.0	0.5	0.1	0.0	0.0	0.1	0.1	0.2	2.9	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	2.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
GART	"GARS-AIRS-GART, PGFT, PRGS"	ENSG00000159131	"Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase"	P22102	21	33503931-33543491	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	"Ligase, Multifunctional enzyme, Transferase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002119, HPA005779"	Approved		Approved	Mitochondria,Cytosol		NA	NA		300000	"Cluster 27: Non-specific - Gene expression"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	Mitochondria	"HPA002119: AB_1849482, HPA005779: AB_1849484"	"unprognostic (3.77e-2)"	"unprognostic (2.25e-2)"	"unprognostic (4.51e-3)"	"unprognostic (1.72e-2)"	"unprognostic (2.30e-2)"	"prognostic unfavorable (5.05e-5)"	"prognostic unfavorable (9.82e-5)"	"unprognostic (2.50e-2)"	"unprognostic (2.76e-3)"	"unprognostic (2.92e-1)"	"prognostic unfavorable (2.19e-4)"	"unprognostic (1.98e-3)"	"prognostic unfavorable (3.95e-6)"	"unprognostic (1.36e-2)"	"unprognostic (2.31e-1)"	"unprognostic (2.28e-1)"	"unprognostic (1.57e-1)"	24.1	20.3	9.2	24.2	12.2	18.8	24.3	11.3	11.9	16.4	10.1	23.2	22.1	18.3	17.1	24.8	21.8	15.9	20.7	8.6	10.5	21.0	29.7	16.0	30.3	11.0	10.3	19.0	22.3	19.9	12.8	26.1	11.7	17.0	29.1	20.9	16.8	16.7	29.1	17.4	19.4	26.3	11.3	20.0	19.7	29.3	10.9	34.4	20.8	21.9	38.6	32.2	16.5	14.0	132.2	61.5	90.3	98.8	61.1	64.2	100.3	82.6	70.8	96.8	101.5	117.7	108.9	174.8	48.5	55.6	124.9	67.9	189.0	130.4	138.3	91.3	111.7	265.2	68.5	78.6	85.2	148.6	66.3	57.3	86.5	113.3	162.5	48.1	91.5	138.4	312.4	108.5	84.9	63.6	158.2	100.0	194.4	186.3	71.8	131.1	166.6	246.7	74.7	69.4	93.1	84.1	116.9	89.1	107.1	81.0	113.0	93.9	68.7	64.9	76.9	56.1	90.9	106.8	159.6	193.0	67.1	171.3	96.2	9.0	24.0	16.3	25.9	33.9	31.4	29.7	25.2	27.1	31.6	24.5	26.4	26.2	10.6	43.9	30.6	23.2	34.1	22.8	9.2	12.2	11.3	11.9	8.6	10.5	11.0	10.3	11.7	11.3	10.9	14.0	21.1	19.2	19.8	17.3	30.1	46.0	50.3	34.1	38.1	18.5	18.6	17.3	19.3	11.5	28.0	14.7	35.5	41.2	21.8	12.4	23.5	28.4	21.7	23.3	36.9	21.9	13.1	40.3	19.1	24.2	37.4	27.2	21.4	23.4	7.6	31.8	16.1	18.0	23.6	5.0	21.1	17.1	22.4	17.0	12.0	6.6	17.4	17.0	12.4	10.3	19.8	13.3	22.6	17.6	19.3	31.5	12.7	18.0	22.7	54.3	16.4	14.3	17.8	28.5	13.1	23.0	23.9	57.2	27.6	34.4	45.9	25.6	21.2	55.0	24.1	46.6
GDA		ENSG00000119125	"Guanine deaminase"	Q9Y2T3	9	72114595-72257193	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 79.7;intestine: 94.8;kidney: 42.9;liver: 60.3"	"Cell type enhanced"	"Detected in many"		"Endometrial ciliated cells: 112.3;Excitatory neurons: 109.3;Glandular and luminal cells: 171.1;Paneth cells: 83.7;Proximal enterocytes: 321.3;Proximal tubular cells: 98.2"	"Cancer enhanced"	"Detected in many"		"renal cancer: 13.1"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A-431: 34.4;EFO-21: 127.9;HeLa: 46.4;hTCEpi: 62.3;OE19: 157.0"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	7	"amygdala: 36.5;basal ganglia: 30.1;cerebral cortex: 60.0;hippocampal formation: 70.7;olfactory bulb: 18.3"	"HPA019352, HPA024099, HPA030387"	Enhanced		Approved	Nucleoplasm		No	NA		1500000	"Cluster 11: Basophils - Unknown function"	"Cluster 45: Intestine - Brush border"	"Cluster 21: OE19 - Mitochondria"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351"	"unprognostic (2.64e-2)"	"unprognostic (7.10e-2)"	"unprognostic (2.83e-2)"	"unprognostic (2.92e-1)"	"unprognostic (4.35e-2)"	"unprognostic (8.45e-2)"	"unprognostic (2.00e-1)"	"unprognostic (5.60e-2)"	"unprognostic (3.26e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.55e-1)"	"unprognostic (5.56e-2)"	"prognostic favorable (2.66e-5)"	"unprognostic (2.23e-1)"	"unprognostic (6.70e-2)"	"unprognostic (2.77e-1)"	"unprognostic (8.30e-4)"	0.3	2.7	57.0	1.2	66.9	0.4	0.2	19.8	79.7	1.6	23.2	10.4	94.3	3.7	0.4	0.4	8.5	15.9	0.1	62.3	52.3	42.9	60.3	0.2	0.4	19.9	26.1	0.2	2.7	8.5	2.8	2.9	25.8	0.1	9.9	0.1	0.0	6.7	1.6	2.2	94.8	0.4	20.5	0.1	3.4	1.2	60.5	0.6	0.1	0.4	4.7	4.0	0.2	42.3	34.4	4.5	0.1	0.1	0.0	0.0	0.8	0.3	24.9	0.0	0.0	3.2	19.3	0.0	127.9	0.0	0.2	2.9	0.2	0.0	0.0	0.4	0.1	0.0	46.4	0.2	0.0	0.1	0.1	0.2	62.3	0.0	0.6	0.1	0.0	0.0	9.6	0.1	0.0	0.2	0.2	0.3	0.2	157.0	0.0	0.0	0.1	1.1	1.1	7.9	0.2	0.6	2.5	0.1	0.1	0.2	0.1	0.2	0.6	0.2	0.4	0.2	0.1	0.3	0.2	0.3	0.1	0.3	0.1	0.8	0.1	0.0	0.2	0.1	0.0	0.1	0.1	0.1	0.0	0.3	0.1	0.2	0.4	0.3	0.1	0.1	0.1	0.0	57.0	66.9	19.8	79.7	62.3	52.3	19.9	26.1	25.8	20.5	60.5	42.3	0.0	0.0	0.5	3.9	1.9	0.0	0.7	19.0	0.0	0.0	0.0	0.0	0.8	14.3	24.7	0.0	0.0	0.2	0.0	65.5	3.9	11.7	1.2	112.3	7.4	0.4	4.8	0.0	109.3	10.7	1.9	0.3	12.2	171.1	0.0	0.0	1.1	56.9	0.2	0.0	22.8	22.1	2.0	1.9	0.4	0.6	0.3	1.2	0.0	5.6	0.6	0.0	0.0	5.0	3.8	6.7	83.7	0.0	0.1	0.8	321.3	98.2	58.6	0.0	0.0	0.8	3.0	1.4	4.7	0.0	0.1	1.9	1.2	0.2	16.1	2.2
GMPR		ENSG00000137198	"Guanosine monophosphate reductase"	P36959	6	16238587-16295549	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 358.6;tongue: 205.0"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 86.1;Endometrial ciliated cells: 118.2;Erythroid cells: 367.1;Melanocytes: 92.5"	"Cancer enhanced"	"Detected in all"		"melanoma: 95.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 14.9"	"Group enriched"	"Detected in all"	6	"granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6"	"Cell line enhanced"	"Detected in many"		"HEL: 193.1;HMC-1: 314.7;SK-MEL-30: 74.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000904, HPA021476"	Uncertain					NA	NA		950000	"Cluster 34: Basophils - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 6: Erythroid cells - Oxygen transport"			"HPA000904: AB_1078998, HPA021476: AB_1849858"	"unprognostic (2.74e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.14e-1)"	"unprognostic (4.97e-3)"	"unprognostic (3.52e-2)"	"unprognostic (1.05e-1)"	"unprognostic (3.06e-1)"	"prognostic favorable (8.07e-4)"	"unprognostic (4.12e-1)"	"prognostic favorable (2.06e-4)"	"unprognostic (3.15e-1)"	"unprognostic (2.86e-1)"	"prognostic favorable (2.94e-5)"	"unprognostic (3.01e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.31e-2)"	"unprognostic (2.17e-1)"	10.0	23.3	28.5	2.8	31.9	29.7	6.5	32.4	21.6	6.6	35.7	15.5	2.7	13.3	16.5	5.3	56.9	3.7	101.7	19.6	38.2	25.5	5.9	9.1	2.5	36.8	45.6	38.0	18.3	14.2	24.9	7.8	35.0	63.1	3.4	2.2	21.5	9.0	358.6	12.4	6.0	9.9	39.7	12.5	36.5	52.3	41.3	6.5	4.4	205.0	1.6	5.2	3.7	33.2	0.0	0.0	0.3	0.0	2.7	2.1	0.1	3.9	15.7	27.2	55.2	1.6	0.4	0.0	8.8	6.0	19.1	0.1	6.7	0.8	4.5	0.0	5.0	193.1	0.1	0.0	11.8	0.8	314.7	3.7	2.8	8.5	0.0	22.2	49.5	0.7	43.9	0.3	4.8	3.8	0.2	4.1	2.0	0.2	7.5	0.0	41.9	0.0	36.1	5.4	9.4	1.2	1.9	3.2	74.4	12.1	3.0	1.4	12.5	0.4	0.2	1.3	7.5	2.3	0.0	0.0	0.9	20.3	21.8	14.9	3.3	0.4	0.7	5.0	1.2	0.2	0.1	0.5	1.5	1.5	0.0	0.2	3.3	9.6	1.7	1.5	0.0	16.0	28.5	31.9	32.4	21.6	19.6	38.2	36.8	45.6	35.0	39.7	41.3	33.2	4.6	0.0	0.0	8.8	1.3	5.1	30.2	0.7	0.6	0.7	5.3	3.8	52.8	35.8	2.7	20.2	0.0	25.3	0.6	1.4	86.1	12.4	16.0	118.2	8.7	6.8	7.8	367.1	3.8	4.9	2.8	10.2	9.2	78.9	55.3	38.9	17.9	5.0	8.9	0.0	11.5	3.2	4.1	6.4	2.1	16.3	34.5	47.4	92.5	2.8	9.2	9.8	2.1	3.0	1.7	3.0	1.2	80.9	1.4	69.9	2.2	15.5	6.4	0.8	0.0	12.6	7.4	6.5	17.2	1.3	1.8	6.8	3.5	19.4	3.8	8.3
GMPR2		ENSG00000100938	"Guanosine monophosphate reductase 2"	Q9P2T1	14	24232422-24239242	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine metabolism"	Oxidoreductase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Proximal tubular cells: 123.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000904, HPA067884, HPA068782"	Approved		Approved	Nucleoplasm,Nucleoli		No	No		50000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Nucleoli	"HPA000904: AB_1078998, HPA067884: AB_2685916, HPA068782: AB_2686032"	"unprognostic (1.95e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.34e-1)"	"unprognostic (1.03e-1)"	"unprognostic (9.86e-2)"	"unprognostic (5.98e-2)"	"unprognostic (3.24e-1)"	"unprognostic (5.21e-3)"	"unprognostic (9.24e-2)"	"unprognostic (3.08e-1)"	"unprognostic (7.88e-2)"	"unprognostic (1.16e-1)"	"prognostic favorable (2.21e-5)"	"unprognostic (2.30e-1)"	"unprognostic (1.96e-1)"	"unprognostic (2.29e-1)"	"unprognostic (1.12e-2)"	45.0	92.1	24.5	19.7	25.7	19.3	44.3	25.8	30.2	44.7	28.2	44.2	30.9	38.2	29.9	38.7	44.9	32.0	39.6	24.8	25.7	70.1	56.0	38.8	26.9	26.2	25.6	51.2	49.0	67.7	48.1	22.7	26.8	41.7	25.5	18.8	41.8	26.3	40.6	35.2	45.8	21.2	26.0	55.9	50.7	21.9	26.1	28.4	58.4	19.8	27.3	43.1	40.3	26.2	27.1	34.2	29.0	26.7	50.9	74.7	40.0	32.1	59.2	47.3	55.7	38.8	24.6	34.7	22.5	49.8	25.5	43.6	42.4	69.2	69.5	19.0	25.5	24.3	25.0	159.1	46.8	53.7	51.4	72.2	54.9	23.6	47.7	61.1	69.7	52.3	12.5	33.3	46.6	51.8	50.1	57.1	34.3	39.5	37.3	33.5	24.2	22.6	69.1	52.7	22.0	36.2	16.9	45.8	52.6	39.5	38.6	41.1	36.2	23.0	15.8	32.0	20.6	59.4	63.1	21.8	16.6	38.9	20.2	24.3	34.2	15.0	19.7	27.5	21.6	13.7	21.5	23.7	35.9	15.9	19.3	20.2	56.0	14.9	27.9	15.8	31.5	26.5	24.5	25.7	25.8	30.2	24.8	25.7	26.2	25.6	26.8	26.0	26.1	26.2	25.2	25.6	18.7	10.7	23.2	11.0	44.5	49.9	27.3	19.6	24.8	32.9	12.5	38.6	35.7	53.3	4.2	67.2	22.6	35.6	101.8	43.6	18.3	29.6	16.6	26.3	10.3	20.6	7.8	33.0	48.5	18.8	17.9	20.0	31.7	29.7	16.8	24.8	50.0	18.5	8.0	19.8	30.5	46.6	14.6	10.5	28.9	32.5	21.4	9.4	32.1	43.3	25.7	7.5	11.7	33.7	32.1	25.2	21.2	19.0	50.2	123.1	43.2	19.7	26.3	16.0	24.5	19.8	10.3	20.7	10.7	49.3	24.6	51.3	28.4	30.5
GMPS	GATD7	ENSG00000163655	"Guanine monophosphate synthase"	P49915	3	155870650-155944020	"Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"GMP biosynthesis, Purine biosynthesis"	Ligase	Proto-oncogene	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"testis: 100.3"	"Cell type enhanced"	"Detected in all"		"Early spermatids: 272.7;Late spermatids: 193.6;Spermatocytes: 171.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046630			Approved	Cytosol		No	No		50000	"Cluster 44: Non-specific - Transcription"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 10: Non-specific - Unknown function"	Cytosol		"HPA046630: AB_2679727"	"unprognostic (3.89e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.59e-2)"	"prognostic unfavorable (5.54e-5)"	"unprognostic (2.30e-1)"	"unprognostic (1.35e-2)"	"prognostic unfavorable (8.73e-7)"	"unprognostic (1.71e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.77e-2)"	"prognostic unfavorable (1.04e-4)"	"unprognostic (2.58e-2)"	"unprognostic (2.79e-2)"	"unprognostic (2.89e-2)"	"unprognostic (3.78e-1)"	"unprognostic (3.55e-3)"	"unprognostic (8.79e-2)"	18.8	20.7	7.2	20.0	7.7	44.6	24.1	22.7	11.0	21.2	7.9	19.7	15.8	20.6	16.0	22.1	17.1	14.0	17.9	6.8	8.5	15.9	22.6	18.2	27.0	7.8	6.8	17.0	26.4	23.1	11.5	20.8	8.3	17.4	22.5	10.1	20.9	17.5	20.0	25.0	16.7	23.4	6.3	19.2	18.0	100.3	8.0	32.3	20.3	16.7	29.4	23.3	19.9	8.8	241.0	93.1	123.0	101.1	49.0	77.0	118.9	99.8	91.6	128.2	128.8	170.5	156.2	171.7	116.1	77.1	98.1	114.6	105.7	104.2	175.0	101.1	81.8	183.2	63.7	92.8	55.9	188.5	68.7	57.3	62.9	99.4	150.5	68.2	79.9	91.3	131.7	63.8	96.8	160.1	153.9	99.4	118.5	130.4	68.3	149.2	145.8	207.5	66.3	103.5	73.3	68.0	111.0	156.0	101.8	83.9	163.6	122.3	56.9	84.4	68.5	121.0	204.3	88.8	58.5	288.5	84.8	137.4	77.0	23.7	16.1	11.5	24.7	20.2	29.1	16.0	23.6	22.3	26.1	11.6	23.3	22.3	2.2	29.3	29.5	14.2	27.1	17.5	7.2	7.7	22.7	11.0	6.8	8.5	7.8	6.8	8.3	6.3	8.0	8.8	23.8	19.2	20.2	19.6	21.5	39.9	47.4	43.9	22.8	22.0	19.5	18.5	16.4	15.7	28.4	7.3	2.1	44.1	21.6	8.3	25.4	33.8	272.7	14.3	37.5	29.9	7.2	68.5	40.9	29.5	56.2	32.4	19.9	18.4	28.6	34.0	22.1	11.6	29.9	21.9	41.6	19.7	26.4	18.5	27.1	193.6	23.0	25.2	23.2	22.5	31.7	17.8	30.9	30.2	31.6	21.3	11.9	24.8	21.9	50.6	17.8	22.8	17.3	8.7	19.7	28.6	65.2	171.2	65.5	29.0	38.2	30.8	30.4	63.2	26.8	42.4
GUCY1A1	"GC-SA3, GUC1A3, GUCY1A3"	ENSG00000164116	"Guanylate cyclase 1 soluble subunit alpha 1"	Q02108	4	155666726-155737059	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 38.4;Alveolar cells type 2: 56.1;Breast glandular cells: 37.4;Breast myoepithelial cells: 24.9;Distal tubular cells: 19.6;Ductal cells: 21.8;Smooth muscle cells: 49.4"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 24.9"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5"	"Group enriched"	"Detected in many"	35	"dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2"	"Cell line enhanced"	"Detected in some"		"HAP1: 6.8;HEK 293: 5.5;Karpas-707: 9.7;MOLT-4: 18.5;RPTEC TERT1: 12.1;RT4: 14.2;SH-SY5Y: 8.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010887, HPA056004, HPA058617"	Uncertain		Supported	Nucleoplasm		NA	NA		7100	"Cluster 40: NK-cells - Unknown function"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm		"CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624"	"unprognostic (4.81e-3)"	"unprognostic (2.60e-1)"	"unprognostic (3.03e-1)"	"unprognostic (2.15e-1)"	"unprognostic (1.99e-2)"	"unprognostic (7.77e-3)"	"unprognostic (1.07e-1)"	"prognostic favorable (2.38e-4)"	"unprognostic (1.85e-3)"	"unprognostic (6.46e-2)"	"unprognostic (3.42e-2)"	"unprognostic (7.16e-2)"	"prognostic unfavorable (7.59e-4)"	"unprognostic (1.60e-2)"	"prognostic unfavorable (3.59e-4)"	"unprognostic (2.27e-1)"	"unprognostic (6.55e-3)"	14.4	7.8	10.1	17.0	24.1	1.2	15.4	2.8	14.0	14.5	0.1	27.1	8.7	16.1	6.2	7.5	9.5	12.6	33.7	12.7	8.0	15.6	8.0	21.0	8.5	5.3	10.0	5.6	13.1	31.4	3.9	25.9	4.5	25.8	10.3	17.0	5.3	13.9	5.1	2.5	9.2	28.9	8.7	14.1	8.6	1.2	10.2	7.5	7.2	18.7	9.2	7.3	6.6	8.5	0.0	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	6.8	0.0	0.0	0.0	5.5	1.3	0.0	0.0	0.0	0.0	0.0	0.8	0.1	0.0	0.0	0.1	0.0	3.6	0.0	9.7	0.0	0.0	18.5	0.0	0.0	0.0	0.2	4.1	0.0	3.0	12.1	14.2	2.5	8.7	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.0	0.2	0.2	0.0	2.3	0.1	0.0	0.0	0.0	2.5	0.1	0.0	0.0	0.1	8.2	10.1	11.5	0.0	1.0	10.1	24.1	2.8	14.0	12.7	8.0	5.3	10.0	4.5	8.7	10.2	8.5	38.4	9.6	56.1	0.0	0.6	0.0	0.0	0.0	0.0	0.0	37.4	24.9	0.0	0.0	6.8	11.0	0.0	0.4	1.7	0.0	19.6	21.8	0.0	5.5	9.7	10.9	0.0	0.0	0.0	2.0	0.3	8.3	0.0	15.2	3.8	3.0	0.0	0.0	4.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.1	0.0	0.0	12.9	2.2	0.0	0.0	0.0	49.4	0.0	0.0	0.0	0.0	0.3	0.6	0.1	0.0	0.0
GUCY1A2	"GC-SA2, GUC1A2"	ENSG00000152402	"Guanylate cyclase 1 soluble subunit alpha 2"	P33402	11	106674019-107018476	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 18.4;placenta: 17.9"	"Group enriched"	"Detected in many"	4	"Excitatory neurons: 353.8;Inhibitory neurons: 141.8;Oligodendrocyte precursor cells: 208.6;Sertoli cells: 105.2;Smooth muscle cells: 107.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 11.8;BJ hTERT+ SV40 Large T+ RasG12V: 13.4;HBF TERT88: 7.1;TIME: 4.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB009534	Uncertain					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"			"CAB009534: AB_2279509"	"unprognostic (7.53e-2)"	"unprognostic (6.67e-2)"	"unprognostic (7.99e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.22e-2)"	"unprognostic (1.23e-2)"	"unprognostic (1.24e-1)"	"unprognostic (6.53e-3)"	"unprognostic (9.70e-3)"	"unprognostic (8.00e-2)"	"unprognostic (2.03e-1)"	"prognostic unfavorable (3.02e-5)"	"unprognostic (2.48e-4)"	"unprognostic (1.62e-1)"	"unprognostic (3.50e-2)"	"unprognostic (1.09e-2)"	3.4	2.0	5.3	0.6	18.4	0.0	1.9	1.6	13.8	12.7	0.0	0.7	0.2	12.3	3.1	0.4	5.9	1.5	2.7	7.1	3.9	1.8	1.7	4.6	0.7	4.7	2.6	1.2	4.3	0.6	0.5	17.9	4.9	1.8	0.5	3.5	0.6	6.8	1.8	0.6	0.4	13.1	0.4	6.0	0.3	1.7	8.6	0.2	1.4	3.6	0.3	0.9	2.8	7.4	0.0	0.2	4.0	0.0	0.2	2.4	2.2	0.3	11.8	1.5	13.4	0.0	0.0	0.0	0.0	0.9	0.4	0.0	0.1	0.0	7.1	0.0	1.1	0.0	0.1	0.0	0.2	0.0	1.6	0.6	0.0	1.8	0.2	0.0	0.8	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.5	0.4	3.6	0.0	0.7	0.5	0.8	0.2	4.6	3.7	3.0	0.8	1.2	0.0	0.0	0.0	0.1	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.3	18.4	1.6	13.8	7.1	3.9	4.7	2.6	4.9	0.4	8.6	7.4	29.5	0.0	0.5	20.2	0.5	1.7	2.2	0.0	1.2	24.0	0.4	0.9	5.1	0.0	0.0	3.7	12.5	0.1	0.0	0.1	0.0	5.8	2.5	0.9	24.2	12.5	0.0	2.7	353.8	0.2	0.0	8.2	0.0	1.1	0.0	42.7	2.2	0.2	0.4	18.5	141.8	0.0	0.0	0.8	1.5	6.5	24.5	1.1	3.6	18.7	0.0	29.3	0.0	208.6	10.7	0.3	0.0	25.2	1.2	2.4	0.0	0.1	0.0	4.8	105.2	20.7	107.0	1.6	1.5	0.7	1.1	0.3	0.5	19.6	0.0	1.5
GUCY1B1	"GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3"	ENSG00000061918	"Guanylate cyclase 1 soluble subunit beta 1"	Q02153	4	155758992-155807811	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"cGMP biosynthesis"	Lyase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	8	"intermediate monocyte: 7.2;non-classical monocyte: 23.9"	"Lineage enriched"	"Detected in many"	13	"monocytes: 23.9"	"Cell line enhanced"	"Detected in many"		"HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010890, HPA020870"	Approved		Approved	Cytosol		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 48: Smooth muscle cells - ECM organization"	Cytosol		"CAB010890: AB_259911, HPA020870: AB_1850444"	"unprognostic (1.44e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.55e-2)"	"unprognostic (9.10e-3)"	"unprognostic (4.69e-2)"	"unprognostic (1.41e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.69e-3)"	"unprognostic (3.03e-3)"	"unprognostic (1.47e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.84e-1)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (7.35e-3)"	"prognostic unfavorable (3.23e-4)"	"unprognostic (2.14e-1)"	"unprognostic (6.36e-3)"	13.8	7.1	23.6	15.6	30.0	2.2	10.0	5.3	36.6	12.6	0.0	28.9	5.8	16.4	6.0	8.1	13.7	13.3	18.7	30.1	28.2	13.2	7.7	16.5	10.4	9.8	13.9	5.8	10.9	50.3	6.0	43.6	22.8	13.6	8.7	34.7	5.5	12.2	5.9	3.5	11.1	25.0	6.4	11.0	13.8	2.4	14.8	7.2	7.3	14.9	7.3	10.0	11.1	17.0	0.0	0.5	6.5	0.0	2.2	11.4	0.0	2.0	3.6	0.2	0.1	0.0	0.0	0.0	3.0	1.1	5.0	0.1	13.6	0.3	0.8	0.0	4.6	46.0	0.0	0.0	1.2	0.0	0.0	5.1	0.4	0.0	0.2	4.2	0.1	10.2	0.0	23.7	3.0	2.1	29.9	0.1	0.4	0.0	3.2	3.5	0.9	0.7	42.9	4.4	0.7	7.8	0.0	0.2	0.0	6.4	0.0	0.0	0.0	7.3	1.6	12.4	9.5	0.3	0.0	0.0	15.6	0.0	0.0	1.4	0.5	0.5	0.0	7.2	0.0	0.1	0.0	0.0	1.8	0.2	0.0	0.0	0.5	1.3	23.9	1.6	0.0	5.8	23.6	30.0	5.3	36.6	30.1	28.2	9.8	13.9	22.8	6.4	14.8	17.0	20.2	6.4	7.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	2.4	2.2	0.0	0.0	0.0	9.2	0.0	1.1	1.1	0.0	5.9	22.9	0.0	3.7	4.3	3.4	0.0	0.0	0.0	4.2	0.2	5.4	0.0	15.5	1.3	4.1	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.6	0.0	0.0	0.0	0.0	3.4	0.0	0.0	0.1	0.0	0.0	22.2	0.0	0.0	0.0	0.0	36.1	0.0	0.0	0.0	0.0	0.7	0.4	0.7	0.0	0.0
GUCY2C	"GUC2C, STAR"	ENSG00000070019	"Guanylate cyclase 2C"	P25092	12	14612632-14696599	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters"	"cGMP biosynthesis"	"Lyase, Receptor"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	20	"intestine: 68.2"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 34.4;Enteroendocrine cells: 176.7;Intestinal goblet cells: 56.0;Paneth cells: 97.9;Proximal enterocytes: 81.5;Undifferentiated cells: 47.6"	"Group enriched"	"Detected in many"	5	"colorectal cancer: 23.9;stomach cancer: 9.1"	"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in some"		"memory B-cell: 1.5"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in some"		"AN3-CA: 1.4;CACO-2: 1.1;CAPAN-2: 1.7;SiHa: 1.6"	"Region enhanced"	"Detected in some"		"midbrain: 1.8"	"Low region specificity"	"Detected in all"			"HPA037655, HPA073759"	Uncertain		Uncertain	Vesicles		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 9: Intestine - Unknown function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 17: Intestinal endocrine cells - Hormone signaling"	Vesicles		"HPA037655: AB_10672388, HPA073759: "	"unprognostic (1.08e-1)"	"unprognostic (2.12e-1)"	"unprognostic (3.58e-2)"	"unprognostic (2.11e-2)"	"unprognostic (1.60e-2)"	"unprognostic (5.67e-3)"	"prognostic unfavorable (1.37e-5)"	"unprognostic (9.14e-2)"	"unprognostic (1.49e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.58e-1)"	"unprognostic (5.40e-2)"	"unprognostic (2.35e-4)"	"unprognostic (8.02e-2)"	"unprognostic (1.64e-1)"	"unprognostic (1.33e-1)"	"unprognostic (1.98e-1)"	0.5	0.2	0.1	3.4	0.3	0.5	0.0	0.2	0.1	0.0	3.0	37.2	68.2	0.3	0.0	1.9	0.0	0.9	2.2	0.2	0.3	0.4	0.3	0.2	0.4	0.4	0.3	0.0	2.2	0.0	0.0	0.2	0.4	0.3	41.4	0.1	0.6	0.0	0.7	1.0	66.5	1.4	0.5	0.2	1.9	0.4	0.3	0.0	0.5	0.0	0.3	0.5	0.2	0.5	0.4	0.0	0.0	1.4	0.0	0.0	0.8	0.0	0.0	0.0	0.0	1.1	1.7	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.2	1.6	0.1	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.3	0.0	0.5	0.3	0.4	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.2	0.0	1.5	0.0	0.0	0.3	1.1	0.0	0.0	1.1	0.0	0.0	0.2	0.0	0.2	0.1	0.3	0.2	0.1	0.2	0.3	0.4	0.3	0.4	0.5	0.3	0.5	0.0	0.0	0.0	1.3	6.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	34.4	0.0	0.0	0.1	0.1	0.0	0.0	176.7	0.0	1.4	0.2	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.8	56.0	0.0	0.3	0.3	0.2	0.0	0.3	0.0	1.0	0.3	0.0	0.0	1.0	0.2	0.4	97.9	0.0	0.1	0.0	81.5	0.8	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.1	0.0	47.6	0.0
GUCY2D	"CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1"	ENSG00000132518	"Guanylate cyclase 2D, retinal"	Q02846	17	8002615-8020342	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters"	"cGMP biosynthesis, Sensory transduction, Vision"	Lyase	"Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, Leber congenital amaurosis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	24	"retina: 34.2"	"Group enriched"	"Detected in some"	4	"Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 58.3"	"Low cancer specificity"	"Detected in single"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	31	"plasmacytoid DC: 8.0"	"Lineage enriched"	"Detected in single"	50	"dendritic cells: 8.0"	"Cell line enriched"	"Detected in some"	5	"JURKAT: 5.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in single"									NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 79: Retina - Phototransduction"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 9: Photoreceptor cells - Phototransduction"				"unprognostic (3.57e-4)"	"unprognostic (5.05e-1)"	"unprognostic (1.49e-1)"	"unprognostic (9.75e-5)"	"unprognostic (5.94e-2)"	"unprognostic (1.86e-1)"	"unprognostic (4.44e-2)"	"unprognostic (3.81e-2)"	"unprognostic (2.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (7.54e-2)"	"unprognostic (4.44e-1)"	"unprognostic (7.59e-5)"	"unprognostic (1.05e-1)"	"unprognostic (3.46e-1)"	"unprognostic (3.08e-1)"	"unprognostic (1.07e-1)"	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	34.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.4	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	1.3	0.1	0.0	0.0	0.0	0.0	0.0	5.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	8.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.3	0.1	0.4	1.3	5.2	5.7	2.1	1.4	3.8	1.9	0.0	1.4	0.0	62.6	1.2	2.7	0.0	1.9	0.1	6.9	0.2	0.1	0.1	0.0	0.0	0.5	0.0	0.7	0.1	0.0	0.6	0.0	0.1	0.0	1.2	1.1	0.0	0.4	0.0	0.0	0.6	0.0	14.9	0.0	0.6	0.0	0.0	0.8	6.1	0.0	0.0	0.1	0.1	0.0	0.4	0.0	1.1	0.0	0.4	0.1	58.3	0.0	0.0	0.0	0.4	0.1	2.4	0.3	2.2	0.1	0.0	0.2	0.5
GUCY2F	"CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2"	ENSG00000101890	"Guanylate cyclase 2F, retinal"	P51841	X	109372906-109482086	"Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins"	"cGMP biosynthesis, Sensory transduction, Vision"	Lyase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	145	"retina: 42.2"	"Cell type enriched"	"Detected in some"	26	"Rod photoreceptor cells: 31.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"THP-1: 1.0"	"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"									NA	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 46: Photoreceptor cells - Phototransduction"							"unprognostic (1.91e-1)"	"unprognostic (4.45e-2)"									"unprognostic (2.96e-1)"	"unprognostic (2.23e-1)"			0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	42.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	1.1	0.4	0.3	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	1.0	0.0	0.5	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	31.3	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0
GUK1		ENSG00000143774	"Guanylate kinase 1"	Q16774	1	228139962-228148984	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA028118, HPA048587, HPA068324"	Approved		Uncertain	Nucleoplasm,Cytosol		NA	NA		240000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 35: Non-specific - Unknown function"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Nucleoplasm	Cytosol	"HPA028118: AB_2756308, HPA048587: AB_2680453, HPA068324: "	"unprognostic (9.15e-2)"	"unprognostic (2.63e-2)"	"unprognostic (3.60e-3)"	"unprognostic (7.91e-2)"	"unprognostic (8.54e-3)"	"unprognostic (1.24e-1)"	"unprognostic (3.55e-3)"	"unprognostic (2.05e-1)"	"unprognostic (3.47e-1)"	"unprognostic (7.32e-2)"	"unprognostic (3.38e-2)"	"unprognostic (5.28e-2)"	"prognostic unfavorable (8.85e-5)"	"unprognostic (2.91e-1)"	"unprognostic (5.41e-1)"	"unprognostic (2.39e-2)"	"unprognostic (6.12e-2)"	226.7	198.9	291.7	93.9	277.9	251.9	213.3	255.3	465.2	187.1	274.1	196.5	113.8	169.2	48.6	333.8	161.8	116.3	240.0	302.8	257.9	230.6	318.1	222.8	124.5	263.1	263.0	146.9	208.9	72.0	165.7	78.9	261.8	161.3	31.5	110.8	191.0	71.6	149.0	285.7	155.0	53.6	266.3	179.4	202.0	107.3	281.3	97.1	151.3	61.8	39.2	188.6	202.4	289.4	356.1	122.4	53.0	164.5	155.6	186.6	264.3	230.8	116.5	130.8	102.8	70.6	239.1	133.4	266.5	151.4	110.0	230.3	45.7	252.0	14.0	203.7	357.1	79.3	292.9	156.3	282.8	90.5	133.0	260.0	150.6	91.9	73.3	94.2	179.2	279.9	219.5	205.1	109.5	295.2	411.4	194.3	166.8	172.6	522.9	155.3	99.9	354.9	125.2	164.1	173.7	311.3	148.7	250.2	309.7	13.5	185.2	191.7	318.5	237.7	157.4	353.4	387.5	186.8	221.9	151.6	300.3	146.2	246.0	379.0	323.8	663.9	420.6	363.0	406.5	265.0	346.8	454.1	279.7	230.8	256.5	323.4	420.1	339.5	390.9	567.3	394.6	571.4	291.7	277.9	255.3	465.2	302.8	257.9	263.1	263.0	261.8	266.3	281.3	289.4	503.7	60.9	87.2	35.3	199.9	660.0	271.5	643.5	215.7	195.5	425.9	448.7	130.8	195.9	312.2	237.3	717.2	241.6	351.2	655.8	694.6	510.9	134.0	212.5	272.0	451.4	269.6	866.9	50.2	685.5	417.9	276.9	189.1	304.2	182.6	162.5	365.5	353.4	407.5	109.4	33.5	426.5	384.5	291.7	557.0	609.3	233.6	265.6	519.4	22.5	355.5	411.0	398.6	16.1	58.6	975.0	718.8	243.8	365.6	571.5	857.7	801.1	231.6	570.9	249.8	158.2	378.6	89.8	100.3	448.6	719.7	262.4	326.7	226.3	331.5	612.2
HK1		ENSG00000156515	"Hexokinase 1"	P19367	10	69269984-69401884	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Glycolysis, Immunity, Inflammatory response, Innate immunity"	"Allosteric enzyme, Kinase, Transferase"	"Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007043, HPA007044, CAB010052"	Supported		Supported	Mitochondria		NA	NA		560000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 25: Spermatids - Spermatogenesis"	Mitochondria		"CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049"	"unprognostic (8.80e-2)"	"unprognostic (1.78e-1)"	"unprognostic (2.03e-1)"	"unprognostic (2.00e-3)"	"unprognostic (1.15e-2)"	"prognostic unfavorable (3.39e-6)"	"unprognostic (1.23e-1)"	"unprognostic (1.97e-1)"	"unprognostic (4.29e-2)"	"unprognostic (1.16e-1)"	"unprognostic (3.93e-3)"	"unprognostic (1.12e-1)"	"unprognostic (1.37e-3)"	"unprognostic (7.25e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.00e-3)"	"unprognostic (3.86e-2)"	47.0	24.4	61.0	45.0	65.7	60.3	40.6	58.0	76.6	54.7	64.2	60.1	13.1	41.3	11.2	129.9	37.0	25.7	150.8	69.1	62.7	49.2	8.5	48.1	34.1	56.7	59.8	19.9	12.3	25.0	44.9	49.3	71.1	52.9	31.9	147.6	67.1	53.1	193.5	102.6	29.2	49.8	40.0	40.3	61.6	77.2	53.5	44.9	71.0	146.7	47.6	74.3	80.9	54.1	101.6	56.6	74.2	71.1	81.0	60.4	47.1	98.3	256.5	128.5	138.0	16.3	11.0	7.3	75.8	165.9	92.9	86.2	69.9	220.0	122.0	67.5	54.5	250.0	58.3	1.1	91.7	5.1	181.2	91.5	125.8	184.5	407.6	160.8	135.4	36.8	424.5	51.3	178.7	167.7	29.7	13.1	113.8	51.7	247.0	44.8	45.0	0.6	88.7	117.4	75.7	88.7	112.6	215.4	65.2	104.3	117.7	16.5	140.4	190.5	86.4	106.5	139.6	61.1	42.8	17.4	247.3	130.4	56.1	68.7	88.8	44.6	41.5	125.2	69.0	33.5	47.9	47.6	81.0	19.9	41.7	33.9	20.9	31.2	135.4	9.1	58.1	110.4	61.0	65.7	58.0	76.6	69.1	62.7	56.7	59.8	71.1	40.0	53.5	54.1	26.1	25.6	32.4	38.2	26.5	48.3	50.5	37.8	43.9	83.9	33.1	21.7	130.6	4.3	34.2	27.6	54.2	70.6	14.6	30.3	13.7	28.6	374.0	32.6	28.0	37.9	18.7	104.8	53.8	30.6	93.3	30.3	41.3	34.5	23.4	72.6	26.7	1.1	49.4	304.5	49.8	28.7	44.7	41.7	21.9	1034.1	15.2	51.3	37.4	29.0	35.3	32.9	20.6	14.1	3.5	54.6	11.1	18.4	19.1	29.1	0.7	1.1	30.7	95.5	19.7	22.2	43.1	5.3	6.2	86.0	51.7	118.9	30.5	28.3	19.3	43.5
HK2		ENSG00000159399	"Hexokinase 2"	P52789	2	74834127-74893359	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Glycolysis	"Allosteric enzyme, Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"retina: 144.0"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 51.7"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"U-87 MG: 172.5"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA028587, HPA061711"	Enhanced		Supported	Vesicles,Centrosome,Mitochondria,Cytosol		NA	NA		100000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 54: Non-specific - Microtubule organization"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Mitochondria, Cytosol"	"Vesicles, Centrosome"	"HPA028587: AB_10602605, HPA061711: "	"unprognostic (1.28e-1)"	"unprognostic (1.52e-3)"	"unprognostic (3.02e-1)"	"unprognostic (3.63e-2)"	"unprognostic (1.69e-1)"	"unprognostic (7.21e-2)"	"prognostic unfavorable (3.65e-4)"	"unprognostic (2.85e-2)"	"unprognostic (2.57e-1)"	"unprognostic (2.17e-1)"	"unprognostic (4.43e-3)"	"unprognostic (2.24e-2)"	"prognostic unfavorable (1.37e-4)"	"unprognostic (1.20e-1)"	"unprognostic (1.17e-1)"	"unprognostic (1.42e-1)"	"unprognostic (7.67e-2)"	58.2	2.7	2.7	14.6	3.9	45.7	16.0	4.8	5.6	7.8	2.7	46.6	2.8	5.1	66.1	19.9	9.7	9.5	7.9	3.5	3.6	1.9	2.7	15.2	5.8	11.1	6.3	14.9	2.9	2.5	1.9	13.1	8.5	4.9	37.3	144.0	14.7	1.1	45.6	14.6	13.0	3.3	5.9	6.9	18.7	32.8	6.0	3.7	14.1	83.7	7.8	27.1	15.9	8.6	55.9	0.4	12.5	45.4	103.3	10.8	46.5	21.3	30.6	23.4	33.4	44.0	9.8	40.7	20.1	9.9	30.2	19.0	57.0	44.7	67.0	11.6	12.5	55.1	12.4	61.0	32.5	80.8	86.3	18.2	47.3	44.5	77.1	26.3	11.3	23.0	49.2	0.2	6.9	39.6	19.8	82.0	45.3	52.4	38.2	31.8	26.2	31.7	14.2	77.2	9.2	44.6	13.5	67.4	27.4	17.8	3.6	12.8	9.4	74.0	13.4	31.2	39.2	27.1	8.2	20.2	172.5	57.9	19.9	16.8	14.0	51.7	0.2	11.0	0.6	1.2	0.8	0.1	11.8	1.3	1.2	1.2	11.2	0.0	7.7	0.3	1.5	4.7	2.7	3.9	4.8	5.6	3.5	3.6	11.1	6.3	8.5	5.9	6.0	8.6	1.6	16.0	45.3	4.9	5.7	51.6	9.5	26.7	5.7	14.8	16.0	5.6	7.2	4.3	24.2	5.5	83.4	2.3	0.6	216.4	0.0	4.6	89.5	5.8	4.1	4.4	39.0	4.2	0.2	4.5	33.5	6.4	14.8	15.0	22.2	27.2	1.4	0.3	15.8	21.9	0.1	37.7	6.1	20.8	35.1	46.0	14.6	22.8	23.2	25.3	18.9	6.3	2.1	0.5	0.7	25.6	108.3	7.9	4.7	34.3	5.4	0.2	15.2	42.1	13.1	19.9	3.3	3.9	4.2	10.7	57.0	8.2	3.6	5.8	51.7	70.0
HK3		ENSG00000160883	"Hexokinase 3"	P52790	5	176880869-176899346	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	Glycolysis	"Allosteric enzyme, Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	4	"bone marrow: 129.3;lymphoid tissue: 76.6"	"Group enriched"	"Detected in some"	13	"Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in some"	7	"cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4"	"Immune cell enhanced"	"Detected in many"		"basophil: 569.7"	"Group enriched"	"Detected in many"	13	"granulocytes: 569.7;monocytes: 200.9"	"Cell line enriched"	"Detected in some"	5	"U-937: 20.6"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			HPA056743	Enhanced					NA	NA		2000000	"Cluster 10: Basophils - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 32: U-937 - Innate immune response"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"			"HPA056743: AB_2683222"	"unprognostic (4.22e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.23e-1)"	"unprognostic (8.63e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.39e-1)"	"unprognostic (8.69e-2)"	"unprognostic (2.11e-1)"	"unprognostic (5.37e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.96e-2)"	"unprognostic (3.82e-1)"	"prognostic unfavorable (3.84e-8)"	"unprognostic (7.02e-2)"	"unprognostic (6.01e-3)"	"unprognostic (1.46e-1)"	"unprognostic (5.42e-2)"	8.4	4.5	0.0	19.0	0.2	129.3	2.6	1.4	1.6	0.8	0.2	2.5	2.0	1.0	0.1	0.9	5.1	2.1	4.0	0.2	0.0	1.8	5.2	25.1	4.2	0.0	0.0	1.0	1.5	0.1	0.7	2.8	0.0	1.1	1.4	0.1	1.5	0.3	0.9	0.5	3.1	7.9	0.0	76.6	2.1	1.3	2.4	1.4	1.3	0.5	0.7	4.5	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	4.5	0.1	0.2	0.0	0.0	0.0	0.0	3.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	20.6	0.0	569.7	92.5	204.8	0.3	179.4	0.2	0.4	0.2	0.1	30.2	0.2	0.1	0.1	32.2	0.2	200.9	1.4	0.2	43.6	0.0	0.2	1.4	1.6	0.2	0.0	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	1.1	0.7	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	11.1	0.1	0.0	0.1	0.0	0.0	0.4	0.0	0.2	0.2	0.0	0.4	1.3	0.0	0.4	0.2	34.5	0.0	0.4	0.0	0.0	43.9	0.9	1.8	0.0	38.8	0.0	1.0	14.6	0.0	2.1	0.0	0.1	0.1	0.0	0.4	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.0	0.4	0.2	0.2	0.1	0.3	0.3	0.1	0.0	0.0
HKDC1	"FLJ22761, FLJ37767"	ENSG00000156510	"Hexokinase domain containing 1"	Q2TB90	10	69220332-69267552	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	Glycolysis	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 53.5;retina: 46.8"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 31.5;Distal enterocytes: 29.0;Ductal cells: 32.6;Endometrial ciliated cells: 50.0;Glandular and luminal cells: 55.2;Muller glia cells: 126.9;Proximal enterocytes: 56.3"	"Cancer enhanced"	"Detected in many"		"colorectal cancer: 20.3"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4"	"Lineage enriched"	"Detected in single"	23	"T-cells: 5.8"	"Cell line enhanced"	"Detected in some"		"A549: 40.1;CACO-2: 57.5;CAPAN-2: 111.4;EFO-21: 33.9;GAMG: 45.4;Hep G2: 33.6;RPTEC TERT1: 81.9"	"Region enhanced"	"Detected in many"		"cerebral cortex: 11.9"	"Low region specificity"	"Detected in all"			"HPA064198, HPA064230"	Enhanced		Enhanced	Mitochondria		No	No			"Cluster 20: T-cells - T-cell receptor"	"Cluster 56: Intestine - Transmembrane transport"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 5: Muller glia cells - Visual perception"	Mitochondria		"HPA064198: AB_2685210, HPA064230: AB_2685219"	"unprognostic (1.29e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.86e-1)"	"unprognostic (8.47e-2)"	"unprognostic (1.55e-1)"	"unprognostic (3.05e-1)"	"unprognostic (6.31e-3)"	"unprognostic (5.03e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.19e-1)"	"unprognostic (1.23e-3)"	"unprognostic (3.11e-1)"	"unprognostic (1.04e-3)"	"unprognostic (1.35e-1)"	"unprognostic (2.24e-1)"	"unprognostic (2.10e-3)"	"unprognostic (2.19e-1)"	0.1	0.0	1.1	2.7	1.3	0.0	0.0	1.4	1.0	1.1	1.4	6.8	53.5	0.9	0.0	0.1	4.6	6.8	0.0	1.0	1.1	13.3	4.6	1.5	1.0	1.3	2.1	0.0	6.2	0.0	0.3	0.0	1.7	0.0	4.2	46.8	0.1	0.0	0.0	0.1	48.0	0.5	1.4	0.3	1.1	1.0	1.0	5.2	9.3	0.0	0.2	0.0	0.1	1.2	1.2	40.1	0.2	0.1	0.0	0.0	0.2	0.0	0.3	0.1	0.1	57.5	111.4	0.0	33.9	0.3	45.4	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.5	33.6	2.7	0.0	0.0	0.0	0.3	0.4	3.2	0.6	0.0	11.3	0.0	0.0	0.7	0.1	0.2	0.1	0.0	11.9	1.3	0.0	1.2	0.1	81.9	0.1	0.0	0.0	0.0	0.0	1.3	0.3	0.0	0.0	0.0	0.4	1.6	0.2	0.8	0.0	0.1	0.0	8.1	0.0	0.5	0.0	0.0	0.0	0.6	0.0	0.5	0.0	3.1	1.0	0.0	0.0	5.8	2.3	0.0	0.2	0.0	0.0	5.4	1.0	1.1	1.3	1.4	1.0	1.0	1.1	1.3	2.1	1.7	1.4	1.0	1.2	0.0	3.2	4.8	11.8	0.7	0.0	0.0	0.3	0.0	1.9	0.0	0.0	1.0	31.5	1.0	16.5	0.0	0.0	0.2	29.0	1.9	32.6	0.6	50.0	4.5	0.5	0.0	0.0	0.4	7.3	0.0	0.2	1.5	55.2	0.0	0.0	0.0	0.4	0.1	3.3	0.5	5.6	0.0	0.3	0.0	0.2	0.3	0.4	0.0	0.0	0.0	126.9	0.0	0.0	0.5	25.5	12.7	0.0	0.3	0.0	56.3	15.7	0.3	5.1	0.0	0.1	0.4	0.0	0.2	0.0	0.0	0.0	1.3	0.1	5.6	0.3
HPRT1	"HGPRT, HPRT"	ENSG00000165704	"Hypoxanthine phosphoribosyltransferase 1"	P00492	X	134460165-134520513	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine salvage"	"Glycosyltransferase, Transferase"	"Disease variant, FDA approved drug targets, Gout"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 226.9;Spermatocytes: 213.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006360, CAB012200"	Enhanced		Supported	Cytosol		NA	NA		9400000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 58: Brain - Synaptic function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis"	Cytosol		"CAB012200: AB_297217, HPA006360: AB_1079082"	"unprognostic (2.02e-1)"	"unprognostic (2.18e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.32e-3)"	"unprognostic (8.55e-2)"	"prognostic unfavorable (1.35e-5)"	"unprognostic (1.58e-2)"	"unprognostic (4.77e-3)"	"unprognostic (4.93e-2)"	"unprognostic (2.02e-2)"	"unprognostic (7.05e-2)"	"unprognostic (1.38e-3)"	"unprognostic (6.00e-2)"	"unprognostic (2.12e-1)"	"unprognostic (2.04e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.51e-1)"	15.6	26.2	37.3	24.3	39.4	54.7	20.4	26.0	63.7	13.6	22.9	25.5	20.4	14.0	62.7	20.3	16.9	14.6	24.5	40.3	47.1	45.5	45.8	14.5	32.1	31.2	32.1	16.8	37.1	21.9	31.5	16.3	34.7	15.4	23.5	74.1	13.5	16.0	22.6	14.8	26.5	17.3	24.6	16.9	32.2	76.1	31.4	31.3	22.1	17.8	30.6	25.4	13.9	31.3	138.0	64.9	18.0	37.2	39.4	56.1	54.1	71.6	68.7	89.5	116.8	58.7	85.5	154.4	158.7	46.7	106.8	82.0	117.4	98.2	153.4	129.2	219.3	84.0	85.0	60.2	38.9	182.9	74.0	41.6	36.1	80.1	126.4	49.5	104.9	90.3	65.5	3.8	71.0	141.0	141.9	157.0	37.0	160.7	171.8	83.8	91.1	158.6	109.6	65.7	113.0	61.6	51.7	41.5	50.1	48.8	35.5	75.2	52.4	60.5	45.6	175.0	181.5	56.5	105.1	0.9	74.6	199.5	33.8	5.8	21.9	20.4	20.8	36.5	30.0	24.0	30.4	27.6	37.9	24.8	24.8	26.9	5.6	39.4	35.5	15.7	57.4	25.3	37.3	39.4	26.0	63.7	40.3	47.1	31.2	32.1	34.7	24.6	31.4	31.3	32.1	19.2	8.2	11.1	39.6	39.6	55.7	75.6	18.8	38.3	26.4	22.0	23.8	30.0	29.9	57.0	4.2	17.9	28.1	16.8	226.9	50.1	11.9	30.1	28.3	39.2	27.5	101.8	55.3	32.3	30.5	29.5	30.1	41.8	34.9	29.0	20.7	22.2	71.2	25.2	43.1	30.4	63.1	60.7	81.7	32.2	40.7	56.2	55.2	10.3	122.5	37.2	26.8	22.1	30.7	36.6	28.2	26.7	30.9	78.1	24.1	30.2	28.9	78.0	52.6	31.6	39.4	213.5	172.6	40.4	38.8	6.0	53.8	30.2	51.3	46.8
IL18BP	IL18BPa	ENSG00000137496	"Interleukin 18 binding protein"	O95998	11	71998613-72005715	"Disease related genes, Metabolic proteins, Predicted secreted proteins"				"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 49.2"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025980, HPA041061"	Enhanced		Approved	"Endoplasmic reticulum"	"Secreted to blood"	NA	NA	3070000	16000000	"Cluster 52: Eosinophils - Transcription"	"Cluster 64: Macrophages - Immune response"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	"Endoplasmic reticulum"		"CAB025980: , HPA041061: AB_2677280"	"unprognostic (2.66e-3)"	"unprognostic (2.04e-3)"	"unprognostic (9.14e-3)"	"unprognostic (1.70e-2)"	"unprognostic (5.58e-3)"	"unprognostic (7.75e-2)"	"unprognostic (1.41e-1)"	"unprognostic (6.20e-2)"	"unprognostic (1.19e-2)"	"unprognostic (1.75e-3)"	"unprognostic (1.74e-1)"	"unprognostic (1.51e-1)"	"prognostic unfavorable (2.93e-6)"	"unprognostic (1.19e-1)"	"unprognostic (4.14e-2)"	"unprognostic (6.76e-2)"	"unprognostic (1.93e-2)"	14.4	18.4	6.0	25.0	6.3	7.9	13.6	7.1	9.1	12.5	4.9	12.7	8.3	10.4	3.5	6.4	10.1	8.1	10.9	5.8	8.3	24.9	15.0	31.1	26.2	8.7	7.8	11.1	8.4	2.5	10.7	17.1	9.0	16.5	11.0	3.8	8.9	4.2	5.0	7.4	17.2	13.5	6.1	49.2	10.2	6.1	8.5	6.5	12.6	2.4	11.9	12.2	8.5	7.3	1.7	2.3	5.1	2.9	1.0	1.6	5.9	3.3	1.8	3.0	4.0	11.7	2.4	1.2	2.2	1.3	3.4	4.0	2.5	2.4	2.0	2.5	3.8	4.5	7.6	3.7	1.3	2.4	12.3	2.4	2.3	2.4	1.2	3.5	6.3	7.9	7.4	2.0	1.8	3.2	3.8	5.7	3.6	1.9	2.2	6.1	5.4	1.9	2.1	4.4	2.8	5.3	3.0	4.2	3.7	4.8	3.6	2.7	13.6	4.2	3.5	5.1	1.9	3.3	1.8	2.1	1.7	11.5	2.3	7.0	20.2	56.1	52.5	72.9	23.9	31.9	27.5	31.6	36.9	20.2	22.5	32.5	8.6	5.2	60.9	53.7	15.1	39.8	6.0	6.3	7.1	9.1	5.8	8.3	8.7	7.8	9.0	6.1	8.5	7.3	14.0	6.4	3.3	0.7	8.0	2.0	0.4	0.7	0.0	3.3	2.1	1.9	1.8	1.5	1.0	0.0	10.4	1.0	7.2	0.5	0.0	3.0	0.0	1.1	1.9	11.1	0.0	0.8	0.7	13.6	1.4	3.4	1.1	1.8	7.6	2.2	10.4	0.5	11.2	3.3	0.5	0.8	0.0	14.2	12.9	0.0	0.9	15.4	0.0	1.0	4.6	1.1	7.2	0.5	0.0	5.4	0.2	0.7	2.3	1.0	1.1	1.9	1.8	3.7	0.0	1.8	1.6	0.7	0.5	0.6	2.0	0.8	6.4	1.6	0.8	0.2
IMPDH1	"LCA11, RP10, sWSS2608"	ENSG00000106348	"Inosine monophosphate dehydrogenase 1"	P20839	7	128392277-128410252	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"GMP biosynthesis, Purine biosynthesis"	"DNA-binding, Oxidoreductase, RNA-binding"	"Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"retina: 106.2"	"Cell type enhanced"	"Detected in many"		"Bipolar cells: 165.8;Cone photoreceptor cells: 141.8;Horizontal cells: 121.1;Rod photoreceptor cells: 205.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"classical monocyte: 89.1;eosinophil: 89.1;intermediate monocyte: 104.5;myeloid DC: 59.9;neutrophil: 197.5;non-classical monocyte: 135.9"	"Group enriched"	"Detected in all"	5	"dendritic cells: 59.9;granulocytes: 197.5;monocytes: 135.9"	"Cell line enhanced"	"Detected in all"		"SK-BR-3: 374.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001400	Approved		Supported	"Cytosol,Rods & Rings"		NA	NA		17000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 79: Retina - Phototransduction"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 56: Bipolar cells - Visual perception"	Cytosol	"Rods & Rings"	"HPA001400: AB_1079139"	"unprognostic (2.84e-1)"	"prognostic unfavorable (3.87e-4)"	"unprognostic (2.23e-2)"	"unprognostic (6.45e-2)"	"prognostic unfavorable (7.31e-5)"	"unprognostic (6.03e-2)"	"prognostic unfavorable (1.12e-7)"	"unprognostic (1.24e-1)"	"unprognostic (7.45e-3)"	"unprognostic (1.03e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.50e-1)"	"prognostic unfavorable (1.78e-12)"	"unprognostic (1.65e-1)"	"unprognostic (1.19e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (3.72e-5)"	54.8	15.9	19.2	33.8	18.5	44.1	38.7	15.7	23.7	18.5	12.7	24.8	8.3	15.1	2.5	30.0	17.7	11.9	23.7	18.1	17.8	15.8	5.7	31.7	25.5	26.3	18.7	20.5	30.1	5.3	26.7	11.4	25.6	27.8	9.8	106.2	29.5	13.1	4.7	23.2	19.1	19.6	17.1	55.9	48.9	16.5	20.0	8.4	11.5	6.2	15.9	29.4	20.4	17.1	111.5	93.2	13.8	102.8	56.5	40.7	38.8	74.1	46.4	61.9	40.1	68.3	35.0	70.8	24.7	111.1	64.4	83.3	78.6	104.1	30.9	25.8	87.1	46.4	66.8	49.1	51.4	62.1	21.1	49.4	49.5	63.2	62.5	29.2	74.5	42.0	46.9	51.8	21.0	76.1	44.1	164.9	77.4	87.7	108.0	51.9	25.2	150.8	27.5	35.1	58.3	55.6	48.0	374.6	68.3	8.6	42.7	119.7	68.5	103.6	37.7	55.0	53.6	38.5	38.3	90.6	53.0	134.0	64.6	11.2	89.1	89.1	22.7	104.5	24.4	15.5	17.9	20.2	59.9	8.9	10.3	12.7	197.5	11.7	135.9	6.0	21.5	58.3	19.2	18.5	15.7	23.7	18.1	17.8	26.3	18.7	25.6	17.1	20.0	17.1	66.8	0.0	11.2	4.6	13.5	8.8	9.3	13.6	9.6	165.8	12.8	9.9	5.1	2.8	8.6	5.5	141.8	3.3	11.1	6.3	5.9	8.1	0.5	4.0	10.9	20.3	9.6	9.7	8.2	17.8	21.3	15.1	44.9	6.5	21.0	46.0	13.6	1.0	46.1	121.1	11.2	10.1	28.5	58.5	21.7	2.0	4.7	38.2	16.0	3.7	65.3	27.3	24.7	2.0	1.5	10.9	3.1	6.8	29.6	21.5	0.8	1.1	7.4	205.5	0.0	9.0	17.3	2.9	16.9	15.8	7.4	2.3	20.4	18.6	11.9	10.3
IMPDH2		ENSG00000178035	"Inosine monophosphate dehydrogenase 2"	P12268	3	49024325-49029447	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"GMP biosynthesis, Purine biosynthesis"	"DNA-binding, Oxidoreductase, RNA-binding"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA001400, CAB020717"	Approved		Supported	"Cytosol,Rods & Rings"		NA	NA		340000	"Cluster 30: Non-specific - Translation"	"Cluster 50: Non-specific - Ribosome"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 10: Non-specific - Unknown function"	Cytosol	"Rods & Rings"	"CAB020717: , HPA001400: AB_1079139"	"unprognostic (2.09e-2)"	"unprognostic (2.91e-1)"	"unprognostic (5.96e-2)"	"unprognostic (1.20e-1)"	"unprognostic (7.31e-3)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (3.22e-4)"	"unprognostic (1.30e-1)"	"unprognostic (2.65e-1)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-2)"	"unprognostic (4.24e-2)"	"unprognostic (1.30e-1)"	"unprognostic (3.85e-1)"	"unprognostic (5.80e-2)"	"unprognostic (2.24e-1)"	"unprognostic (4.47e-2)"	109.1	89.3	42.1	68.0	43.0	105.3	188.6	44.2	41.6	169.6	37.3	100.8	75.3	113.5	48.2	169.0	199.3	64.9	70.0	39.5	45.2	67.5	63.5	83.3	78.7	46.9	43.2	331.0	313.9	55.7	65.0	81.0	46.6	97.6	121.2	22.0	87.9	66.4	272.8	180.0	74.1	100.9	45.1	68.6	93.4	36.1	43.8	95.9	75.1	124.4	122.0	119.7	137.5	48.9	271.8	150.6	201.6	211.3	309.2	558.4	200.6	180.8	298.2	425.5	361.0	265.8	235.2	485.7	128.2	220.7	119.5	183.1	433.6	369.8	371.1	119.9	135.3	362.2	205.0	257.8	264.4	388.4	139.0	497.7	403.1	414.6	756.5	331.8	313.5	337.7	221.7	266.2	354.1	213.4	327.0	258.9	269.0	255.4	300.2	143.5	218.4	487.9	251.7	166.2	130.2	128.9	198.1	216.5	341.3	170.2	277.3	166.1	151.4	181.0	347.7	449.5	468.8	253.3	193.3	227.3	214.1	421.9	188.1	21.8	27.8	10.7	43.6	46.8	81.9	79.7	58.4	47.7	51.1	79.6	84.9	71.6	10.9	60.5	41.6	38.0	40.2	45.2	42.1	43.0	44.2	41.6	39.5	45.2	46.9	43.2	46.6	45.1	43.8	48.9	40.5	64.1	60.9	3.9	92.2	202.7	255.0	253.8	229.9	16.1	202.7	231.8	32.3	74.4	122.4	36.8	14.6	327.3	34.5	51.1	80.3	133.6	2.7	49.0	120.5	60.9	60.7	112.5	2.9	187.1	280.6	104.4	70.3	51.2	66.1	98.0	52.8	24.9	95.3	15.2	4.1	124.4	114.0	55.9	105.4	6.7	123.3	50.0	88.9	1.0	67.3	26.5	24.7	4.0	5.2	108.8	70.8	71.1	64.6	160.1	47.4	92.0	53.7	15.8	39.5	149.4	215.1	22.6	62.5	195.7	195.6	314.0	52.3	166.8	266.5	157.2
ITPA	"C20orf37, dJ794I6.3, HLC14-06-P"	ENSG00000125877	"Inosine triphosphatase"	Q9BY32	20	3208868-3223870	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase	"Disease variant, Epilepsy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022824, HPA073963"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA		120000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 37: Intestine - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	"Nucleoplasm, Cytosol"		"HPA022824: AB_1851960, HPA073963: "	"unprognostic (1.58e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.73e-1)"	"unprognostic (3.57e-1)"	"unprognostic (4.63e-2)"	"unprognostic (1.53e-2)"	"prognostic unfavorable (2.54e-5)"	"unprognostic (1.11e-2)"	"unprognostic (1.68e-1)"	"unprognostic (1.76e-1)"	"unprognostic (1.83e-1)"	"unprognostic (2.28e-1)"	"unprognostic (1.94e-2)"	"unprognostic (8.34e-2)"	"unprognostic (3.63e-1)"	"unprognostic (1.24e-1)"	"unprognostic (1.84e-1)"	26.2	37.1	16.7	21.2	17.5	26.4	25.0	16.9	20.0	24.8	18.2	25.3	27.0	24.0	13.0	43.9	29.9	16.7	20.8	18.2	16.8	34.2	28.2	22.4	27.6	17.0	16.5	21.2	21.9	24.2	13.0	19.8	17.0	20.3	19.2	6.9	26.4	16.1	26.5	33.6	23.2	18.5	17.3	27.0	27.1	12.3	18.0	24.8	33.5	15.1	21.4	24.1	25.7	18.5	118.2	91.1	44.0	49.1	29.7	42.7	30.9	50.9	72.4	65.9	58.8	75.0	106.6	52.5	46.9	48.7	65.7	101.9	62.3	79.8	46.6	32.9	91.6	123.9	39.1	117.6	55.5	54.5	41.4	41.5	60.3	64.4	40.9	28.6	52.5	39.5	88.7	34.2	62.6	55.2	66.0	156.5	77.2	132.1	89.6	61.4	60.7	135.0	96.7	39.2	67.4	80.9	41.4	154.0	106.3	19.3	60.1	94.2	37.9	76.5	42.4	51.7	116.0	52.0	68.4	94.2	32.9	102.8	83.0	32.8	61.5	22.9	47.7	78.2	41.7	48.9	43.6	49.0	74.5	50.2	32.4	39.5	3.4	64.5	56.9	70.7	61.0	48.0	16.7	17.5	16.9	20.0	18.2	16.8	17.0	16.5	17.0	17.3	18.0	18.5	29.4	22.4	47.0	15.3	38.0	40.1	50.5	93.2	56.9	20.4	48.8	58.3	9.8	34.3	59.3	44.1	14.6	74.4	45.9	37.5	58.7	104.2	2.7	51.8	64.4	29.4	27.5	24.6	12.0	105.1	128.2	41.8	48.4	60.9	42.5	49.7	29.3	32.1	116.6	5.0	9.2	53.1	54.9	42.4	54.0	3.7	31.1	49.0	40.9	5.6	90.3	21.0	41.2	14.1	21.5	102.2	59.9	22.2	34.5	53.5	51.6	94.5	37.9	24.5	19.7	35.4	45.0	16.8	17.6	58.8	49.2	56.2	47.2	53.3	79.9	66.0
LPO	SPO	ENSG00000167419	Lactoperoxidase	P22079	17	58218548-58268518	"Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins"	"Hydrogen peroxide"	"Antimicrobial, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	404	"salivary gland: 1026.8"	"Group enriched"	"Detected in some"	6	"Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1"	"Not detected"	"Not detected"			"Region enriched"	"Detected in single"	4	"midbrain: 2.5"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in single"	10	"THP-1: 9.9"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			HPA028688	Enhanced	Supported			"Secreted to digestive system"	NA	NA				"Cluster 24: Salivary gland - Salivary secretion"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 30: Mammary glandular cells - Lactation"			"HPA028688: AB_10601909"	"unprognostic (2.74e-1)"	"unprognostic (5.12e-2)"	"unprognostic (4.14e-3)"	"unprognostic (1.56e-3)"	"unprognostic (2.41e-2)"	"unprognostic (9.71e-2)"	"unprognostic (2.06e-2)"	"unprognostic (1.53e-1)"	"unprognostic (2.40e-2)"	"unprognostic (6.27e-3)"	"unprognostic (6.32e-2)"	"unprognostic (2.56e-1)"	"unprognostic (0.00e+0)"	"unprognostic (3.41e-2)"	"unprognostic (3.15e-1)"	"unprognostic (2.72e-2)"	"unprognostic (1.22e-1)"	0.0	0.0	0.1	0.0	0.0	0.6	0.0	0.1	0.1	0.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.1	0.1	0.3	0.0	0.0	0.0	0.0	0.0	2.5	0.0	1.2	0.0	0.0	0.1	0.0	0.0	0.0	0.1	1026.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	9.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.1	0.3	0.0	2.5	0.0	0.0	0.5	0.1	0.2	0.0	0.0	0.0	0.0	0.3	0.7	0.0	0.0	0.7	25.2	0.5	0.7	0.0	0.6	0.0	0.0	0.0	0.3	0.0	0.0	0.1	8.3	0.3	0.1	0.3	0.0	0.0	0.6	0.0	0.0	0.2	0.0	0.1	1.3	0.0	0.4	0.0	0.2	1.7	0.3	0.0	0.0	0.0	0.0	14.1	0.3	0.1	0.0	0.0	0.6	0.0	0.0	0.0	0.1	0.3	0.0	0.4	0.0	0.5	1.4	0.1	0.0	0.3	0.0	0.2	0.1	2.6	0.4	0.0	0.3	0.0	0.2	0.0	0.5	0.5
MPO		ENSG00000005381	Myeloperoxidase	P05164	17	58269855-58280935	"Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	61	"bone marrow: 4023.1"	"Cell type enriched"	"Detected in some"	30	"Erythroid cells: 87.4"	"Cancer enhanced"	"Detected in single"		"stomach cancer: 1.1"	"Low region specificity"	"Detected in some"			"Immune cell enhanced"	"Detected in some"		"classical monocyte: 6.2"	"Low lineage specificity"	"Detected in many"			"Group enriched"	"Detected in some"	94	"HL-60: 3517.4;NB-4: 4589.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000059, HPA021147, HPA061464"	Enhanced		Supported	Nucleoplasm,Vesicles	"Intracellular and membrane"	No	NA	576000000	24000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 24: NB-4 - Immune response"	"Cluster 12: Non-specific - Cell cycle regulation"	Vesicles	Nucleoplasm	"CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531"	"unprognostic (1.91e-1)"	"unprognostic (9.08e-2)"	"unprognostic (4.62e-2)"	"unprognostic (2.90e-2)"	"unprognostic (2.13e-3)"	"unprognostic (2.78e-1)"	"unprognostic (3.23e-1)"	"unprognostic (2.91e-1)"	"unprognostic (2.56e-1)"	"unprognostic (1.68e-1)"	"unprognostic (6.92e-2)"	"unprognostic (8.34e-3)"	"unprognostic (4.91e-2)"	"unprognostic (3.07e-3)"	"unprognostic (2.83e-1)"	"unprognostic (1.14e-2)"	"unprognostic (8.05e-2)"	0.5	0.4	0.8	0.6	0.6	4023.1	0.3	0.6	1.1	0.0	0.3	0.2	0.0	0.2	1.1	0.1	0.1	0.3	1.1	0.8	0.7	0.2	1.8	8.4	1.7	0.9	1.0	0.1	0.1	0.0	1.5	1.4	0.9	0.2	0.2	0.4	66.3	0.1	1.1	4.3	0.2	0.3	0.8	21.7	0.1	0.4	0.8	10.9	0.3	0.3	0.2	0.5	0.1	0.7	0.4	0.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.1	3517.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4589.9	0.0	0.0	0.0	5.3	3.2	0.6	0.0	0.0	0.0	0.5	1.1	0.0	0.0	0.0	0.0	43.1	0.0	0.0	0.0	1.3	0.0	0.0	0.0	1.1	0.0	4.0	0.0	0.0	6.2	0.0	0.0	3.0	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	1.4	0.0	0.6	0.0	0.1	7.5	0.8	0.6	0.6	1.1	0.8	0.7	0.9	1.0	0.9	0.8	0.8	0.7	0.0	0.0	0.5	0.7	0.3	0.0	0.0	0.0	0.0	0.4	0.2	0.3	0.4	0.0	0.0	0.0	0.0	0.0	1.8	0.0	1.9	0.0	0.5	0.1	0.0	0.1	0.0	87.4	0.3	0.2	0.9	0.7	0.0	0.0	0.0	0.0	0.7	0.3	0.9	0.0	0.2	0.0	0.0	1.2	0.0	1.3	0.0	2.9	0.0	0.0	2.3	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.0	0.2	0.0	1.2	0.1	0.1	0.3	0.1	0.0	0.1	0.6	0.0	0.0	0.0
NME1	"NDPKA, NM23, NM23-H1"	ENSG00000239672	"NME/NM23 nucleoside diphosphate kinase 1"	P15531	17	51153559-51162428	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism"	"Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008467, CAB040571, HPA041113"	Supported		Supported	"Nucleoplasm,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		21000000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 77: Retina - Visual perception"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 10: Non-specific - Unknown function"	Cytosol	"Nucleoplasm, Plasma membrane"	"CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305"	"unprognostic (2.24e-1)"	"unprognostic (2.01e-1)"	"unprognostic (3.48e-3)"	"unprognostic (5.96e-2)"	"unprognostic (9.71e-2)"	"unprognostic (2.33e-3)"	"prognostic unfavorable (2.60e-5)"	"unprognostic (4.54e-2)"	"unprognostic (3.35e-1)"	"unprognostic (2.33e-3)"	"unprognostic (2.90e-2)"	"unprognostic (1.01e-1)"	"prognostic unfavorable (2.07e-9)"	"unprognostic (9.01e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.83e-1)"	"unprognostic (9.46e-2)"	63.6	84.4	79.3	74.7	81.6	77.0	63.1	78.7	102.2	38.2	79.0	60.1	38.8	49.7	46.8	91.0	48.6	20.8	37.7	88.0	92.0	65.4	83.2	41.3	73.9	83.9	78.4	33.6	67.8	52.8	47.4	39.2	82.4	38.7	77.6	218.4	50.7	30.4	35.6	57.5	33.1	66.3	76.5	48.5	41.8	25.3	81.0	61.1	41.3	20.9	95.8	72.2	48.9	80.1	483.6	833.1	285.9	444.8	118.6	183.7	479.7	355.3	227.3	652.2	489.7	656.9	288.1	754.2	372.4	304.1	272.4	252.1	542.5	553.3	553.4	398.4	729.3	504.9	605.8	975.9	237.1	575.8	243.8	177.8	341.7	493.1	458.6	120.6	404.6	247.8	739.0	270.0	392.8	720.4	715.2	647.1	390.7	957.5	739.3	446.9	587.6	751.3	511.5	320.2	418.6	461.1	188.1	521.0	385.3	246.2	554.0	419.6	279.5	476.9	452.2	307.0	774.4	374.0	840.9	956.3	286.2	480.4	385.8	1.1	55.0	2.1	47.2	77.1	69.3	96.4	50.3	53.8	134.0	67.6	54.3	60.4	1.7	69.6	48.6	84.8	49.1	68.4	79.3	81.6	78.7	102.2	88.0	92.0	83.9	78.4	82.4	76.5	81.0	80.1	53.1	32.1	30.5	0.0	71.3	132.4	97.5	198.8	88.8	283.3	98.8	118.1	34.2	65.8	92.3	71.7	285.7	180.0	25.4	54.2	150.6	211.3	34.2	40.2	107.2	85.1	89.7	81.8	0.0	201.5	269.7	85.0	64.2	37.2	45.7	113.5	27.8	123.3	207.1	40.4	0.0	107.4	101.7	25.7	88.9	93.7	61.2	48.9	129.9	0.0	47.2	105.6	27.8	0.0	0.0	194.0	50.5	58.6	113.8	170.6	12.2	195.2	42.0	323.7	13.1	83.0	182.9	22.7	98.8	139.4	133.1	88.5	38.0	215.5	157.7	98.2
NME1-NME2	"NM23-LV, NMELV"	ENSG00000011052	"NME1-NME2 readthrough"		17	51153590-51171744	"Metabolic proteins, Predicted intracellular proteins"				"Evidence at protein level"	"Evidence at protein level"			"Tissue enhanced"	"Detected in many"		"retina: 51.2"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 43.5;Basal keratinocytes: 38.4;Basal respiratory cells: 23.3;Club cells: 31.1;granulocytes: 22.7;Langerhans cells: 35.0;Melanocytes: 23.2;Suprabasal keratinocytes: 51.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB002169, HPA008467, HPA041113, CAB076057"	Approved		Approved	Cytosol		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 77: Retina - Visual perception"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 11: Alveolar cells - Smell perception"	Cytosol		"CAB002169: AB_563917, CAB076057: , HPA008467: AB_1079492, HPA041113: AB_2677305"	"unprognostic (2.39e-1)"	"unprognostic (5.29e-2)"	"unprognostic (9.70e-2)"	"unprognostic (5.13e-2)"	"prognostic favorable (6.66e-4)"	"unprognostic (2.46e-2)"	"unprognostic (4.82e-3)"	"unprognostic (8.39e-2)"	"unprognostic (2.30e-2)"	"unprognostic (1.53e-1)"	"unprognostic (4.58e-6)"	"unprognostic (1.03e-1)"	"unprognostic (2.74e-6)"	"unprognostic (1.84e-1)"	"unprognostic (9.72e-2)"	"unprognostic (1.50e-1)"	"unprognostic (1.43e-3)"	12.3	21.0	7.2	15.1	7.4	10.9	8.7	6.5	10.3	8.7	6.3	6.7	3.6	9.3	0.8	14.7	9.4	2.2	9.9	8.7	6.8	12.4	16.4	9.2	8.7	7.8	6.7	5.6	16.6	6.4	11.9	7.1	7.8	6.8	2.9	51.2	13.8	2.2	12.9	12.2	4.9	6.8	6.5	7.9	9.0	3.0	7.7	6.2	7.4	3.6	3.7	13.1	9.9	7.3	22.4	5.5	21.2	48.3	27.9	13.1	7.7	32.3	20.8	15.9	9.5	11.1	8.6	30.1	34.3	41.3	33.2	21.9	25.1	44.7	8.8	51.0	46.6	15.2	9.1	22.7	30.5	25.5	42.2	25.4	36.2	21.2	31.4	49.6	28.0	38.8	21.2	36.7	12.3	14.6	141.2	37.4	19.6	66.5	9.5	49.5	21.0	85.0	23.0	9.4	70.1	56.4	13.9	112.7	38.3	37.8	87.8	86.3	34.1	57.0	14.6	76.8	26.2	60.8	52.2	41.4	26.7	24.6	46.4	0.4	16.0	0.7	18.2	24.1	26.9	14.1	15.7	17.1	45.9	23.4	13.9	16.9	1.7	14.4	11.9	28.4	16.9	20.8	7.2	7.4	6.5	10.3	8.7	6.8	7.8	6.7	7.8	6.5	7.7	7.3	0.0	16.0	43.5	0.0	1.5	38.4	0.0	23.3	2.2	0.0	0.0	0.0	2.2	0.0	31.1	0.0	0.0	0.0	0.1	8.0	0.0	0.0	0.0	0.2	0.2	5.1	1.8	0.4	3.9	0.0	0.1	12.1	1.5	0.2	22.7	0.1	0.4	0.6	0.0	0.0	3.5	7.2	10.2	0.0	35.0	0.0	0.3	6.8	23.2	0.0	0.0	0.0	0.0	2.0	0.9	0.0	1.1	0.0	2.0	0.0	0.0	0.1	16.3	0.0	0.0	0.0	16.4	0.1	0.0	3.8	51.9	0.0	3.0	0.0	7.8	0.1
NME2	"NDPKB, NM23-H2"	ENSG00000243678	"NME/NM23 nucleoside diphosphate kinase 2"	P22392	17	51165435-51171744	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism, Transcription, Transcription regulation"	"Activator, DNA-binding, Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"CAB036213, CAB036214, CAB036215, HPA041113"	Approved		Supported	"Plasma membrane,Midbody ring,Cytosol"		Yes	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 50: Non-specific - Ribosome"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 61: Squamous epithelial cells - Keratinization"	Cytosol	"Plasma membrane, Midbody ring"	"CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305"	"unprognostic (7.21e-3)"	"prognostic unfavorable (4.74e-4)"	"unprognostic (4.85e-2)"	"unprognostic (1.15e-2)"	"unprognostic (8.86e-2)"	"unprognostic (1.42e-2)"	"prognostic unfavorable (7.09e-4)"	"unprognostic (6.62e-3)"	"unprognostic (5.68e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.38e-1)"	"unprognostic (6.41e-2)"	"prognostic unfavorable (1.55e-6)"	"unprognostic (2.82e-1)"	"unprognostic (9.09e-2)"	"unprognostic (8.87e-2)"	"unprognostic (3.19e-2)"	503.5	428.3	308.0	259.5	319.0	329.4	489.1	328.0	379.9	439.2	431.1	409.2	335.1	383.4	236.1	610.6	350.6	187.0	403.9	313.7	338.6	478.1	428.4	339.6	288.9	326.6	320.7	500.1	632.0	201.8	234.9	204.8	321.3	367.7	330.4	63.3	432.4	247.5	545.7	540.3	307.6	286.2	326.8	336.0	403.5	77.8	333.3	190.0	305.3	353.7	289.1	463.5	464.2	333.4	1638.6	2233.9	466.1	913.7	969.3	1399.2	1449.2	1091.7	954.0	1404.8	1053.5	1789.7	792.3	1314.3	1662.9	913.0	706.6	956.2	947.3	1273.3	1035.7	1604.8	3283.2	1120.3	1345.8	2513.4	1116.1	1736.0	760.5	1324.1	1420.0	901.9	1466.4	914.6	860.9	856.5	1541.7	773.7	956.1	2741.9	931.3	2144.8	831.4	2974.6	3364.2	875.9	1731.8	2157.2	1417.9	1800.2	1160.6	641.9	674.1	1472.7	1583.0	806.1	1201.7	1268.5	1013.5	1462.8	1158.2	1135.2	1774.8	1520.9	2176.6	1558.1	815.1	919.1	819.2	66.8	243.4	14.0	166.7	325.5	235.6	338.9	211.9	183.3	439.5	259.2	153.5	170.0	13.8	251.6	282.5	478.1	211.2	298.2	308.0	319.0	328.0	379.9	313.7	338.6	326.6	320.7	321.3	326.8	333.3	333.4	9.7	28.9	67.2	0.0	146.8	14.5	8.3	10.8	918.0	0.9	41.6	35.9	0.0	22.8	85.7	5.5	0.0	10.0	10.1	7.1	37.2	47.4	0.6	16.4	34.3	60.9	14.6	298.2	0.0	34.5	27.8	99.0	438.3	21.3	42.9	6.8	22.9	37.6	16.4	0.0	0.0	19.3	8.2	34.8	17.4	2.1	25.7	136.7	10.6	0.0	55.5	0.4	2.1	0.0	0.0	40.7	15.6	12.8	778.5	7.6	11.7	33.8	63.6	0.8	6.6	10.2	43.3	0.6	5.6	1490.1	14.9	8.8	87.0	6.8	25.0	11.0
NME3	"DR-nm23, NDPKC, NM23-H3"	ENSG00000103024	"NME/NM23 nucleoside diphosphate kinase 3"	Q13232	16	1770286-1771730	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Nucleotide metabolism"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HEK 293: 70.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA041113, HPA052733"	Approved		Approved	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA		12000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 72: Non-specific - Transcription"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Cytosol	"HPA041113: AB_2677305, HPA052733: AB_2681930"	"prognostic favorable (6.81e-5)"	"unprognostic (1.41e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.15e-3)"	"unprognostic (1.26e-1)"	"unprognostic (1.61e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.54e-2)"	"unprognostic (1.13e-1)"	"unprognostic (6.22e-3)"	"unprognostic (4.40e-2)"	"unprognostic (4.43e-2)"	"unprognostic (7.09e-3)"	"unprognostic (1.79e-1)"	"unprognostic (3.84e-1)"	"unprognostic (3.64e-1)"	"unprognostic (6.11e-3)"	34.0	84.4	21.3	8.0	22.7	3.9	34.2	21.0	36.3	41.9	16.8	47.7	15.9	36.7	3.4	27.2	44.3	2.1	36.0	20.2	23.1	44.6	36.3	29.1	5.4	23.7	22.2	43.7	37.2	4.5	71.9	5.2	19.6	59.4	3.1	1.8	35.9	13.0	17.1	31.1	33.8	3.2	22.5	39.4	38.6	16.0	22.0	1.0	40.3	3.1	1.9	38.5	33.5	24.9	1.6	26.9	0.6	21.8	6.1	3.2	2.5	15.7	4.5	2.7	2.1	0.0	31.8	0.4	42.6	2.2	2.8	23.0	1.3	8.8	0.3	32.1	70.9	0.0	12.0	13.0	11.3	5.5	9.8	14.0	7.9	2.7	1.5	5.1	5.6	0.2	11.2	4.4	2.7	40.4	0.4	10.8	28.0	5.4	21.5	15.3	0.3	43.5	4.5	1.2	30.6	23.6	47.1	35.2	4.2	1.2	33.7	13.1	19.9	5.8	21.4	18.5	10.8	11.1	3.7	2.5	8.1	0.9	13.3	10.0	50.7	34.6	33.3	49.6	32.9	36.8	46.3	31.4	45.1	31.9	39.6	31.3	10.8	44.8	55.4	70.3	45.4	41.3	21.3	22.7	21.0	36.3	20.2	23.1	23.7	22.2	19.6	22.5	22.0	24.9	128.8	35.3	62.7	69.9	64.6	72.5	141.3	97.7	179.8	116.3	147.3	165.6	28.0	90.1	76.6	126.9	60.5	86.6	77.9	76.2	60.7	62.9	22.1	66.5	102.9	84.1	135.5	25.7	34.6	37.6	46.3	100.9	76.0	77.6	50.8	71.6	99.9	63.0	74.8	65.6	30.2	109.4	50.8	60.3	91.0	20.3	149.5	71.1	81.8	29.0	136.5	126.9	77.2	40.7	63.7	37.0	104.7	127.5	93.1	98.4	157.2	150.2	70.9	126.7	118.3	75.9	100.8	2.0	40.4	100.9	65.6	46.1	87.3	183.8	107.6	100.6
NME4	"NDPKD, nm23-H4, NM23H4"	ENSG00000103202	"NME/NM23 nucleoside diphosphate kinase 4"	O00746	16	396725-410367	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Lipid transport, Nucleotide metabolism, Transport"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 250.5;Erythroid cells: 311.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB045997, HPA072588"	Approved		Supported	Mitochondria		Yes	No			"Cluster 26: Non-specific - Mitochondria"	"Cluster 15: Liver - Metabolism"	"Cluster 14: REH - Unknown function"	"Cluster 33: Fibroblasts - ECM organization"	Mitochondria		"CAB045997: AB_11126630, HPA072588: AB_2686538"	"unprognostic (3.27e-1)"	"prognostic unfavorable (6.53e-4)"	"unprognostic (3.70e-2)"	"unprognostic (7.16e-3)"	"unprognostic (1.32e-1)"	"unprognostic (2.00e-1)"	"unprognostic (4.40e-2)"	"unprognostic (4.46e-3)"	"unprognostic (1.98e-1)"	"unprognostic (3.12e-1)"	"unprognostic (3.74e-2)"	"unprognostic (7.79e-3)"	"prognostic unfavorable (1.61e-7)"	"unprognostic (3.78e-2)"	"unprognostic (2.16e-1)"	"unprognostic (6.04e-2)"	"unprognostic (3.08e-1)"	89.3	136.1	78.3	26.2	75.6	127.7	72.9	73.5	101.5	88.1	77.3	192.9	21.9	79.5	55.7	50.1	89.1	41.2	101.2	76.4	81.7	60.4	175.2	48.3	21.1	88.6	77.9	86.8	43.7	56.7	64.3	30.8	79.8	143.7	23.5	11.1	70.4	81.9	34.7	31.4	59.7	51.9	78.6	43.8	97.7	44.7	80.3	29.3	51.6	27.2	15.8	145.6	64.3	73.6	1.0	305.4	265.6	366.7	104.0	181.0	59.5	143.6	170.4	211.8	180.6	205.4	176.2	3.0	105.8	230.2	76.9	3.9	145.0	153.9	62.0	126.5	218.7	151.9	40.2	279.9	195.7	111.0	53.1	234.7	79.8	130.5	12.8	152.2	137.6	210.7	159.6	25.8	160.4	255.4	98.5	139.2	271.8	76.1	67.8	485.8	59.3	79.0	150.6	1.2	77.7	419.2	36.8	2.7	139.9	97.2	178.3	257.5	174.0	149.7	216.8	101.8	36.8	2.7	2.0	83.1	65.8	19.8	177.2	12.9	13.3	39.8	14.9	11.9	12.7	27.6	14.4	16.3	17.6	29.9	26.0	13.4	4.2	2.5	10.6	58.3	0.9	10.7	78.3	75.6	73.5	101.5	76.4	81.7	88.6	77.9	79.8	78.6	80.3	73.6	52.2	0.0	13.9	18.6	40.6	32.2	56.3	49.0	40.9	15.2	116.6	135.8	44.5	52.9	25.1	58.8	2.1	71.7	45.7	19.3	250.5	116.5	5.0	30.8	113.3	55.3	45.1	311.8	16.8	40.3	26.1	87.3	29.6	59.8	29.9	199.9	55.6	132.2	131.2	8.4	21.1	38.6	26.4	46.5	68.6	21.6	89.2	35.4	62.2	10.3	46.5	45.9	19.6	10.1	3.6	58.3	23.8	94.8	34.5	121.8	9.0	75.5	7.9	5.6	52.6	40.1	105.8	1.7	32.7	38.6	24.6	21.8	26.2	89.4	54.9	60.9
NME5	"nm23-H5, RSPH23"	ENSG00000112981	"NME/NM23 family member 5"	P56597	5	138115175-138139443	"Metabolic proteins, Predicted intracellular proteins"	"Differentiation, Spermatogenesis"	"Developmental protein"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"fallopian tube: 37.2;testis: 53.3"	"Group enriched"	"Detected in many"	4	"Early spermatids: 704.9;Endometrial ciliated cells: 205.8;Late spermatids: 256.5;Respiratory ciliated cells: 431.9;Spermatocytes: 326.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	4	"RPTEC TERT1: 29.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035648, HPA044555, HPA058103"	Enhanced		Approved	"Nucleoplasm,Nuclear bodies"		Yes	NA				"Cluster 42: Ciliated cells - Cilium & Cell projection"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 49: Ciliated cells - Cilium organization"	"Nucleoplasm, Nuclear bodies"		"HPA035648: AB_2674719, HPA044555: AB_10960286, HPA058103: "	"unprognostic (2.49e-2)"	"unprognostic (7.63e-4)"	"unprognostic (9.97e-2)"	"prognostic favorable (7.24e-5)"	"unprognostic (3.27e-2)"	"unprognostic (2.27e-1)"	"unprognostic (3.04e-3)"	"unprognostic (3.06e-1)"	"unprognostic (1.34e-1)"	"unprognostic (2.39e-2)"	"unprognostic (1.83e-2)"	"unprognostic (2.14e-1)"	"prognostic favorable (1.76e-4)"	"unprognostic (9.14e-4)"	"unprognostic (1.11e-3)"	"unprognostic (3.45e-1)"	"unprognostic (3.16e-2)"	1.4	6.5	9.7	0.5	10.5	0.0	4.5	9.2	11.7	8.6	18.6	2.1	0.2	4.9	23.1	1.0	37.2	8.7	3.6	10.5	9.2	20.5	0.5	4.5	0.4	10.5	12.3	5.3	4.4	24.3	8.9	0.1	12.1	5.0	1.1	12.9	3.7	4.5	0.4	0.3	0.6	3.1	9.6	0.2	2.8	53.3	11.0	0.7	12.4	0.6	0.2	2.1	0.6	8.9	0.0	0.0	3.9	4.3	0.0	0.0	0.0	0.7	0.4	0.7	0.3	0.1	1.8	0.0	1.1	0.1	0.7	0.0	0.0	0.0	0.2	0.0	0.9	0.0	0.0	0.0	1.7	0.0	0.0	2.1	0.0	0.9	0.0	3.8	0.4	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.6	0.0	1.4	0.0	0.0	0.0	29.9	0.0	6.7	2.5	0.0	0.8	4.9	1.7	0.5	1.6	0.0	0.7	0.0	0.0	0.9	0.4	0.8	0.0	5.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.7	10.5	9.2	11.7	10.5	9.2	10.5	12.3	12.1	9.6	11.0	8.9	1.0	6.4	7.5	26.8	0.3	0.6	8.5	41.1	0.0	11.7	9.0	7.9	4.3	8.6	38.1	33.1	14.6	0.5	0.1	0.3	86.1	23.8	704.9	205.8	9.2	3.5	5.4	0.0	57.9	4.0	0.0	4.2	2.6	12.7	0.0	7.7	3.6	0.6	0.1	6.7	42.2	3.3	44.7	0.0	0.3	256.5	9.0	1.4	10.6	3.7	0.6	19.1	0.0	11.1	8.1	4.2	0.3	13.9	0.0	4.8	0.2	92.3	431.9	25.8	0.0	0.5	12.6	326.8	24.7	0.0	0.3	0.0	0.8	10.9	1.7	5.9
NME6	"IPIA-ALPHA, NM23-H6"	ENSG00000172113	"NME/NM23 nucleoside diphosphate kinase 6"	O75414	3	48290722-48301685	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Apoptosis, Nucleotide metabolism"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA017909	Approved		Approved	Vesicles		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 7: Non-specific - Mitochondria"	Vesicles		"HPA017909: AB_1854530"	"unprognostic (7.31e-3)"	"unprognostic (1.87e-1)"	"unprognostic (8.19e-3)"	"unprognostic (2.09e-2)"	"unprognostic (8.52e-2)"	"unprognostic (2.20e-1)"	"prognostic unfavorable (2.17e-7)"	"unprognostic (1.90e-1)"	"unprognostic (1.56e-1)"	"unprognostic (4.00e-3)"	"unprognostic (1.32e-1)"	"unprognostic (2.98e-1)"	"prognostic favorable (3.18e-5)"	"unprognostic (1.98e-2)"	"unprognostic (1.57e-2)"	"unprognostic (1.23e-1)"	"unprognostic (9.50e-2)"	8.7	7.7	6.3	10.4	6.4	8.1	12.1	9.2	6.3	10.2	8.7	11.6	13.2	9.3	8.5	12.1	14.8	8.9	13.5	7.1	6.5	11.1	10.3	10.2	12.2	5.9	6.3	12.4	11.6	12.4	6.0	14.2	5.7	9.5	11.5	7.6	10.9	8.7	17.7	10.0	10.4	12.4	4.9	9.6	11.5	6.2	6.4	9.4	12.2	17.2	13.7	9.6	9.0	6.3	30.0	19.1	24.3	18.3	18.2	23.4	22.1	27.2	18.3	37.5	27.3	30.5	26.5	30.1	14.0	20.5	36.5	10.1	21.9	27.2	24.1	36.1	21.3	17.9	24.1	26.6	25.7	24.3	20.7	19.7	33.8	34.4	42.9	19.3	19.8	21.1	33.9	23.6	14.0	13.9	21.4	11.3	22.3	19.5	23.3	12.7	22.9	25.3	21.2	23.6	7.7	12.7	19.8	21.0	26.1	17.8	23.9	22.5	22.1	8.3	33.0	21.2	39.4	27.0	40.9	26.1	16.3	31.9	18.4	47.3	33.4	76.4	40.9	36.0	36.6	43.5	37.4	35.2	39.9	38.0	28.1	27.2	37.3	40.4	42.1	34.5	33.5	25.1	6.3	6.4	9.2	6.3	7.1	6.5	5.9	6.3	5.7	4.9	6.4	6.3	13.1	28.9	20.7	2.3	16.4	5.0	8.5	18.2	9.6	11.9	14.1	13.6	10.4	15.7	19.4	9.2	14.6	49.5	18.4	8.2	39.2	24.8	2.6	16.1	17.5	12.8	4.2	8.0	2.5	30.1	41.6	12.4	11.7	11.8	10.1	22.8	7.9	7.9	34.4	10.1	3.2	10.8	12.2	9.3	9.7	1.7	11.8	13.7	16.0	1.9	23.4	17.6	18.6	2.5	2.7	31.3	8.3	7.2	10.8	12.8	16.6	16.4	30.6	11.5	13.1	7.7	12.2	9.3	15.0	12.4	4.1	19.7	14.7	15.1	12.8	7.1
NME7	"CFAP67, FLJ37194, NM23-H7"	ENSG00000143156	"NME/NM23 family member 7"	Q9Y5B8	1	169132531-169367948	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 274.9;Inhibitory neurons: 307.2;Oligodendrocytes: 277.7;Respiratory ciliated cells: 142.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA028334, HPA038014, HPA054289"	Approved		Approved	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 42: Ciliated cells - Cilium & Cell projection"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm		"HPA028334: , HPA038014: AB_10673037, HPA054289: AB_2682437"	"unprognostic (1.28e-1)"	"unprognostic (8.52e-2)"	"unprognostic (6.21e-2)"	"unprognostic (6.30e-2)"	"unprognostic (1.11e-1)"	"unprognostic (7.44e-3)"	"prognostic unfavorable (3.24e-5)"	"unprognostic (1.42e-1)"	"unprognostic (1.96e-1)"	"unprognostic (2.90e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.00e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.67e-2)"	"unprognostic (1.12e-1)"	"unprognostic (7.75e-2)"	"unprognostic (2.74e-1)"	6.7	10.6	9.4	5.5	9.9	3.5	11.1	8.4	12.2	13.0	11.8	9.8	3.9	12.9	13.3	7.5	27.7	10.0	6.2	10.8	10.8	12.5	7.9	7.6	5.6	10.2	10.0	13.6	7.2	18.3	14.2	4.8	9.9	8.0	5.6	20.7	4.3	11.5	4.1	4.0	4.6	14.9	9.3	4.4	5.8	16.0	9.9	11.1	13.6	4.9	6.4	8.8	6.2	9.6	24.3	23.6	26.4	20.9	25.1	26.1	9.4	16.6	24.2	28.5	35.8	13.8	33.7	7.1	29.4	14.5	38.8	16.2	15.6	35.3	46.1	25.5	12.3	12.5	21.3	14.1	18.5	23.8	8.3	18.8	20.1	29.5	38.3	39.2	40.8	21.1	12.6	9.5	28.8	7.1	22.7	16.8	26.5	27.4	25.2	16.1	29.4	15.3	46.0	7.3	27.5	40.6	23.0	7.6	18.4	28.3	24.4	16.4	25.4	17.4	59.5	16.5	40.2	11.7	21.3	14.8	19.8	8.2	17.8	1.6	3.9	2.1	9.6	6.3	11.6	9.9	12.0	9.9	6.3	9.3	10.1	11.7	1.1	11.4	9.8	5.1	14.9	5.3	9.4	9.9	8.4	12.2	10.8	10.8	10.2	10.0	9.9	9.3	9.9	9.6	12.3	6.4	10.9	97.6	9.0	14.4	34.5	61.9	15.4	18.9	13.7	14.7	5.1	20.0	29.3	27.6	25.0	7.6	9.2	2.1	23.5	26.6	43.2	75.7	20.4	12.8	17.5	13.7	274.9	8.9	7.4	21.1	12.8	22.2	21.5	21.8	13.9	11.2	14.6	28.6	307.2	4.1	36.7	4.1	11.9	13.8	18.0	6.5	8.8	64.6	3.3	23.8	10.3	106.1	277.7	16.9	6.0	20.7	7.2	8.6	4.9	40.9	142.9	64.9	19.7	21.2	24.7	67.7	21.9	9.2	10.2	2.7	18.7	26.4	6.0	16.5
NPR1	"ANPa, ANPRA, GUCY2A, NPRA"	ENSG00000169418	"Natriuretic peptide receptor 1"	P16066	1	153678688-153693992	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters"	"cGMP biosynthesis"	"Lyase, Receptor, Vasoactive"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 67.1"	"Group enriched"	"Detected in many"	6	"Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8"	"Group enriched"	"Detected in all"	4	"ovarian cancer: 39.2;renal cancer: 12.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	6	"ASC diff: 158.5"	"Region enriched"	"Detected in all"	5	"olfactory bulb: 18.7"	"Low region specificity"	"Detected in many"			HPA031087			Approved	"Nucleoplasm,Nucleoli,Plasma membrane"		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Nucleoli	"Nucleoplasm, Plasma membrane"	"HPA031087: AB_10601975"	"unprognostic (2.54e-1)"	"unprognostic (3.03e-3)"	"unprognostic (6.31e-2)"	"prognostic unfavorable (3.97e-4)"	"unprognostic (1.55e-1)"	"unprognostic (6.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.03e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.27e-2)"	"prognostic favorable (2.49e-4)"	"unprognostic (1.27e-1)"	"unprognostic (6.69e-2)"	"unprognostic (1.16e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.06e-1)"	"unprognostic (1.74e-2)"	67.1	8.7	1.7	3.4	1.5	0.0	44.3	1.4	1.4	8.8	1.5	10.1	1.5	31.0	5.5	4.3	36.4	5.9	15.8	1.3	1.4	28.8	4.3	24.2	2.3	1.5	1.5	27.7	3.9	8.4	3.8	17.7	1.5	4.4	2.0	0.1	3.7	12.1	7.2	6.6	9.3	9.7	1.8	2.2	8.8	1.3	2.4	1.9	14.0	11.1	1.3	12.8	9.7	1.4	0.0	1.3	0.1	0.0	158.5	0.6	0.1	0.0	0.0	0.1	0.1	0.1	0.6	0.0	0.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	28.0	0.0	19.0	0.0	0.0	0.3	0.0	0.3	0.0	0.1	3.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.8	0.0	0.0	15.9	0.0	0.0	2.1	0.0	0.1	0.0	1.9	0.0	5.7	1.0	0.1	0.0	0.2	0.0	0.0	8.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.7	1.5	1.4	1.4	1.3	1.4	1.5	1.5	1.5	1.8	2.4	1.4	99.6	0.0	6.9	0.0	0.2	1.5	0.5	0.0	0.6	0.0	0.5	0.5	4.5	2.8	0.0	14.7	0.0	0.2	0.1	0.0	0.0	0.7	9.1	6.2	8.8	52.5	0.0	0.0	0.0	0.0	1.3	15.2	0.0	15.4	0.0	0.0	132.8	2.4	0.3	0.0	0.0	0.0	0.0	4.7	4.0	11.5	10.2	0.5	0.0	0.0	5.2	0.0	0.0	0.0	0.0	1.0	0.0	4.1	0.0	0.5	0.0	4.0	0.0	0.0	0.0	1.4	2.2	0.5	0.1	0.2	1.0	0.7	0.3	1.4	0.2	0.0
NPR2	"AMDM, ANPb, ANPRB, GUCY2B, NPRB"	ENSG00000159899	"Natriuretic peptide receptor 2"	P20594	9	35791591-35809732	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"cGMP biosynthesis, Osteogenesis"	"Lyase, Receptor"	"Disease variant, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 35: Non-specific - Unknown function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"				"unprognostic (2.93e-2)"	"unprognostic (8.22e-3)"	"unprognostic (9.25e-3)"	"unprognostic (3.59e-2)"	"unprognostic (6.13e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.56e-1)"	"unprognostic (2.40e-1)"	"unprognostic (3.06e-1)"	"unprognostic (1.49e-1)"	"unprognostic (3.99e-2)"	"unprognostic (6.99e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.24e-1)"	"unprognostic (7.86e-2)"	12.4	8.2	9.3	1.7	9.4	0.3	10.3	14.4	9.9	25.7	7.7	15.6	1.8	20.5	8.7	3.2	15.1	3.2	12.8	9.1	11.4	6.7	8.6	9.1	2.3	11.8	9.4	9.4	3.2	1.3	13.8	4.7	11.5	10.9	2.8	4.1	5.3	6.5	10.8	8.3	7.5	9.9	8.2	4.9	7.8	4.8	10.7	2.2	6.0	8.6	1.7	12.1	14.7	7.9	0.0	2.9	2.2	0.0	30.9	21.1	1.9	9.3	20.2	7.0	6.4	4.5	4.3	1.8	3.0	17.9	12.8	1.2	3.6	0.2	6.1	2.2	1.0	1.8	4.3	3.4	20.1	0.4	0.0	23.8	1.8	8.9	0.6	7.6	12.7	2.5	0.7	0.2	13.4	1.0	0.5	0.8	3.5	1.0	3.7	2.4	0.2	0.5	1.8	1.4	1.1	0.7	0.4	0.1	0.6	3.8	0.2	0.0	8.2	8.5	7.8	3.2	1.2	0.5	0.6	4.8	10.4	0.6	5.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.3	0.0	9.3	9.4	14.4	9.9	9.1	11.4	11.8	9.4	11.5	8.2	10.7	7.9	2.7	3.2	3.4	35.6	0.0	1.1	0.6	0.6	1.2	5.1	0.7	1.4	0.7	1.5	0.3	0.0	2.1	0.4	0.5	0.7	0.0	0.6	0.3	1.4	9.2	4.4	0.0	0.0	69.1	0.8	0.2	7.2	0.5	2.0	1.3	9.6	6.1	4.5	0.4	3.3	68.9	0.7	0.0	0.3	2.1	0.3	9.3	0.3	0.0	34.7	0.0	6.8	0.0	51.8	16.3	0.6	3.6	7.9	0.2	2.7	0.2	0.6	1.1	2.2	0.0	5.1	3.4	4.5	3.1	0.1	1.6	0.3	0.7	0.8	1.1	0.4
NT5C	"cdN, DNT-1, DNT1, PN-I, UMPH2"	ENSG00000125458	"5', 3'-nucleotidase, cytosolic"	Q8TCD5	17	75130225-75131757	"Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA021581, HPA023632"	Approved		Supported	Cytosol		NA	NA		760000	"Cluster 10: Basophils - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Cytosol		"HPA021581: AB_1854663, HPA023632: AB_1854662"	"unprognostic (3.83e-2)"	"unprognostic (4.45e-2)"	"unprognostic (2.39e-1)"	"unprognostic (3.61e-2)"	"unprognostic (1.26e-1)"	"unprognostic (9.21e-2)"	"prognostic unfavorable (3.05e-4)"	"unprognostic (1.26e-1)"	"unprognostic (7.25e-2)"	"unprognostic (8.26e-3)"	"unprognostic (7.15e-2)"	"unprognostic (2.22e-1)"	"unprognostic (6.57e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.10e-1)"	"unprognostic (2.13e-1)"	"prognostic favorable (7.66e-4)"	31.6	31.4	14.5	17.9	15.9	16.3	31.8	16.5	17.4	37.0	14.8	43.0	24.5	34.7	5.2	45.9	32.1	8.4	32.6	14.1	16.7	47.8	29.1	29.2	18.3	17.1	15.5	37.5	33.7	11.7	18.9	10.2	15.6	35.7	13.1	8.7	25.8	15.3	41.1	33.8	43.7	7.6	16.6	40.7	36.8	15.2	15.5	16.0	37.7	16.1	15.2	37.9	35.9	18.4	52.5	77.7	25.3	26.5	7.5	15.4	33.7	29.5	26.2	29.7	18.8	29.5	58.3	35.5	21.5	21.0	5.2	33.7	18.1	37.7	16.5	16.1	51.3	40.5	68.7	50.0	38.0	38.8	17.2	23.1	17.4	21.3	57.0	11.9	33.0	27.6	38.4	16.8	30.2	51.2	28.0	39.0	26.5	43.6	50.6	24.9	32.9	50.9	39.3	26.7	30.0	60.1	28.3	34.8	43.9	14.0	49.8	27.2	20.4	25.0	62.1	9.8	40.3	33.3	5.6	41.1	23.8	23.3	40.4	183.7	29.7	48.9	39.2	49.6	27.7	94.9	25.5	33.6	37.9	87.4	21.6	33.5	14.4	72.6	50.7	50.4	45.2	30.2	14.5	15.9	16.5	17.4	14.1	16.7	17.1	15.5	15.6	16.6	15.5	18.4	23.0	32.1	19.5	22.2	132.9	47.4	86.1	108.8	90.5	66.0	58.8	101.9	16.4	77.2	35.2	58.8	20.9	64.9	85.8	272.8	78.2	102.2	2.1	53.2	53.5	26.6	64.1	59.5	7.7	121.4	100.4	59.8	181.5	43.2	46.3	59.0	11.7	41.9	74.5	42.1	8.0	133.4	52.9	55.7	64.4	6.8	59.4	56.2	58.7	18.7	108.4	55.9	98.9	19.6	19.2	127.5	221.6	47.4	51.2	115.8	231.6	144.2	31.1	65.5	32.9	39.0	107.6	19.0	49.6	89.4	44.3	31.2	67.4	98.4	152.8	85.9
NT5C1A	"CN-I, CN-IA, CN1, CN1A, MGC119199, MGC119201"	ENSG00000116981	"5'-nucleotidase, cytosolic IA"	Q9BXI3	1	39659121-39672038	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"skeletal muscle: 72.4;tongue: 28.6"	"Cell type enhanced"	"Detected in single"		"Inhibitory neurons: 1.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	12	"SH-SY5Y: 17.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA050283, HPA054158"	Supported					NA	NA				"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"HPA050283: AB_2681072, HPA054158: AB_2682402"	"unprognostic (7.85e-2)"				"unprognostic (1.60e-1)"	"unprognostic (6.19e-1)"		"unprognostic (1.51e-3)"	"unprognostic (7.19e-2)"		"unprognostic (2.87e-1)"	"unprognostic (3.34e-1)"	"unprognostic (1.32e-1)"	"unprognostic (3.29e-2)"		"unprognostic (1.81e-2)"		0.2	2.6	1.4	0.1	0.8	0.0	0.0	4.8	5.4	0.2	0.0	0.0	0.0	0.1	0.1	3.0	0.2	0.0	11.4	0.7	1.6	0.4	0.0	0.0	0.0	3.0	3.1	0.1	3.9	0.0	0.0	0.0	2.0	0.5	0.0	0.1	0.1	0.1	72.4	0.0	0.1	0.1	1.4	0.0	0.1	0.2	2.2	0.1	0.0	28.6	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.2	17.8	0.0	0.0	0.3	0.0	0.0	1.4	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.8	4.8	5.4	0.7	1.6	3.0	3.1	2.0	1.4	2.2	1.1	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
NT5C1B	"AIRP, CN-IB"	ENSG00000185013	"5'-nucleotidase, cytosolic IB"	Q96P26	2	18562872-18589572	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	13	"testis: 35.5"	"Group enriched"	"Detected in some"	29	"Early spermatids: 159.5;Late spermatids: 300.4"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in some"											HPA056683	Uncertain		Approved	"Nucleoplasm,Nucleoli,Plasma membrane"		NA	NA			"Cluster 29: Plasmacytoid DCs - Unknown function"	"Cluster 83: Testis - Spermatogenesis"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 25: Spermatids - Spermatogenesis"	"Nucleoli, Plasma membrane"	Nucleoplasm	"HPA056683: AB_2683207"	"unprognostic (4.18e-2)"	"unprognostic (1.20e-2)"	"unprognostic (7.67e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.02e-1)"	"unprognostic (4.97e-2)"	"unprognostic (4.96e-2)"	"unprognostic (4.84e-1)"	"unprognostic (8.49e-2)"	"unprognostic (4.42e-2)"	"unprognostic (2.91e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.61e-1)"	"unprognostic (6.96e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.77e-1)"	0.1	0.5	0.2	0.2	0.3	0.4	0.1	0.2	0.2	0.1	2.6	0.1	0.7	0.1	0.0	1.0	0.1	0.7	0.6	0.1	0.1	0.3	0.2	0.2	0.3	0.3	0.5	0.0	0.4	0.0	0.1	0.2	0.2	0.2	0.0	0.1	0.2	0.0	0.0	1.1	0.2	0.0	0.1	0.2	0.8	35.5	0.4	0.0	0.7	0.0	0.0	0.3	0.1	0.2	1.2	0.2	0.1	0.0	0.0	0.0	0.1	0.9	0.0	0.0	0.0	0.0	1.2	0.5	0.1	0.0	0.7	0.3	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.2	0.4	0.1	0.0	1.0	0.0	0.1	0.2	0.2	0.6	0.1	0.2	0.3	0.0	1.1	0.8	0.4	0.9	0.1	0.5	0.1	0.2	0.2	0.6	0.5	0.3	1.0	0.1	0.3	0.2	0.7	0.9	0.0	0.4	0.0	0.0	0.0	0.4	0.0	0.7	0.0	0.4	0.4	0.1	0.3	0.8	0.7	0.0	0.2	0.0	1.2	0.1	0.1	0.2	0.3	0.2	0.2	0.1	0.1	0.3	0.5	0.2	0.1	0.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	159.5	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	300.4	2.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	7.7	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0
NT5C1B-RDH14		ENSG00000250741	"NT5C1B-RDH14 readthrough"		2	18555545-18589564	"Metabolic proteins, Predicted intracellular proteins"				"Evidence at transcript level"	"Evidence at transcript level"			"Tissue enriched"	"Detected in single"	126	"testis: 16.6"	"Group enriched"	"Detected in some"	97	"Early spermatids: 52.3;Late spermatids: 64.8"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"											HPA056683	Uncertain		Approved	"Nucleoplasm,Nucleoli,Plasma membrane"		NA	NA				"Cluster 74: Testis - Spermatogenesis"		"Cluster 34: Spermatids - Unknown function"	"Nucleoli, Plasma membrane"	Nucleoplasm	"HPA056683: AB_2683207"																		0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	16.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	52.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	64.8	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0
NT5C2	"cN-II, GMP, NT5B, PNT5, SPG45, SPG65"	ENSG00000076685	"5'-nucleotidase, cytosolic II"	P49902	10	103087185-103277605	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	"Allosteric enzyme, Hydrolase"	"Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 141.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003751	Approved					NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 22: Epithelial cell types - Mixed function"			"HPA003751: AB_1854664"	"unprognostic (8.18e-2)"	"unprognostic (1.98e-1)"	"unprognostic (2.55e-2)"	"unprognostic (2.46e-1)"	"unprognostic (5.54e-2)"	"unprognostic (4.87e-3)"	"unprognostic (2.24e-2)"	"unprognostic (1.72e-1)"	"unprognostic (6.41e-2)"	"unprognostic (9.59e-2)"	"unprognostic (2.93e-3)"	"unprognostic (6.20e-2)"	"unprognostic (3.26e-2)"	"unprognostic (3.70e-2)"	"unprognostic (6.40e-2)"	"unprognostic (3.43e-1)"	"unprognostic (1.50e-1)"	24.6	27.0	25.0	19.0	27.2	29.7	23.0	27.3	28.5	37.6	36.8	27.3	9.9	18.8	17.3	67.1	26.5	16.4	28.5	25.2	28.8	32.5	27.8	30.8	18.3	26.9	29.5	32.4	22.0	21.7	34.0	17.9	27.2	32.4	16.7	47.3	46.4	18.4	51.6	19.9	20.4	13.4	26.4	32.8	22.3	30.8	27.2	28.6	55.4	18.1	24.5	33.3	42.7	28.6	148.4	52.5	32.6	67.5	27.2	33.2	18.2	66.0	64.7	29.9	32.4	34.6	91.7	49.2	47.7	45.6	27.6	62.8	23.4	33.8	38.3	40.3	21.6	38.7	21.1	39.6	48.5	64.2	21.0	50.4	34.1	28.0	24.8	57.5	25.6	19.4	29.4	36.4	54.5	73.8	53.7	64.6	34.6	43.2	68.6	102.6	30.0	19.6	43.3	72.5	10.0	24.9	35.8	25.9	50.3	33.7	39.2	38.1	30.5	20.5	24.8	39.7	51.7	32.9	71.6	85.5	23.9	64.6	7.8	29.5	16.5	31.3	10.0	18.8	10.3	8.9	8.4	8.7	14.7	5.2	6.7	8.0	27.4	14.4	23.0	9.6	9.3	10.5	25.0	27.2	27.3	28.5	25.2	28.8	26.9	29.5	27.2	26.4	27.2	28.6	16.2	83.3	34.9	141.7	17.2	7.4	29.0	26.9	5.7	24.4	13.9	13.6	2.6	18.6	60.4	27.6	45.9	19.4	23.3	48.7	11.7	28.5	103.7	29.5	17.1	19.8	11.5	12.4	79.8	26.0	11.7	17.5	25.5	46.2	8.8	18.2	13.9	17.4	19.9	47.1	83.6	17.6	18.3	29.8	14.2	61.9	24.8	27.1	26.6	78.7	25.9	85.5	16.5	70.4	107.5	57.9	23.1	13.5	21.0	35.7	11.7	15.3	44.1	59.1	32.9	22.9	21.7	25.3	20.5	22.9	7.5	35.0	16.6	15.8	18.0	80.5
NT5C3A	"cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1"	ENSG00000122643	"5'-nucleotidase, cytosolic IIIA"	Q9H0P0	7	33014114-33062797	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	"Hydrolase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 87.4"	"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 191.0;Paneth cells: 186.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA010520, HPA010630, HPA029058"	Uncertain		Supported	"Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol"	"Intracellular and membrane"	NA	NA		10000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 51: Myeloid cells - Hemostasis"	"Endoplasmic reticulum, Cytosol"	"Nucleoplasm, Nuclear bodies"	"HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380"	"unprognostic (7.50e-2)"	"unprognostic (3.10e-1)"	"unprognostic (1.14e-1)"	"unprognostic (2.69e-2)"	"unprognostic (1.22e-1)"	"unprognostic (5.56e-2)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (3.25e-2)"	"unprognostic (3.12e-2)"	"unprognostic (2.82e-3)"	"unprognostic (2.08e-2)"	"unprognostic (1.98e-1)"	"prognostic unfavorable (1.70e-4)"	"unprognostic (9.37e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.12e-3)"	"unprognostic (3.43e-3)"	12.4	14.3	11.4	26.1	11.4	32.6	21.3	15.2	15.6	12.6	10.8	51.9	40.0	16.9	14.3	18.6	15.9	23.4	16.6	11.5	11.5	22.4	11.8	17.6	30.8	11.1	11.8	13.4	21.4	9.7	7.5	16.3	11.5	12.3	51.0	20.4	9.7	10.0	87.4	28.7	37.3	13.2	12.7	22.9	27.0	9.5	12.0	22.5	17.1	51.0	45.8	23.8	14.4	13.1	42.2	27.6	25.2	29.6	21.2	16.1	20.3	44.8	30.5	29.2	38.9	19.9	115.1	100.4	27.7	29.6	48.3	63.8	28.3	30.8	40.4	16.2	36.2	54.7	36.5	28.7	23.3	55.6	36.9	21.7	23.8	35.9	63.0	16.4	22.2	33.2	43.3	24.8	37.3	29.9	25.0	87.8	27.8	47.1	31.2	25.9	22.9	60.0	87.8	39.8	28.1	37.0	31.1	52.4	66.6	24.5	35.2	33.5	19.8	25.1	20.9	42.6	55.7	50.6	69.0	54.8	20.6	34.9	42.5	112.5	25.9	82.5	26.6	32.7	30.6	64.0	34.2	30.8	22.1	63.6	34.5	29.1	103.8	28.2	39.2	20.6	56.2	37.9	11.4	11.4	15.2	15.6	11.5	11.5	11.1	11.8	11.5	12.7	12.0	13.1	39.1	22.4	13.7	30.7	85.1	46.8	40.9	85.3	47.8	23.9	22.6	18.9	16.9	32.9	40.4	16.5	41.7	36.9	42.5	191.0	29.4	34.4	5.7	40.9	21.0	40.8	119.6	127.1	45.3	79.0	31.6	35.2	42.8	21.4	17.7	38.3	30.0	18.9	25.0	1.7	49.4	98.9	40.7	31.2	23.5	5.0	33.8	111.4	26.6	29.0	37.0	23.4	55.6	48.2	52.4	48.3	186.6	22.2	43.8	45.7	91.8	84.8	53.7	27.1	13.1	30.7	24.9	46.4	24.0	35.5	38.9	28.3	53.7	23.3	71.0	65.9
NT5C3B	"cN-IIIB, MGC20781, NT5C3L"	ENSG00000141698	"5'-nucleotidase, cytosolic IIIB"	Q969T7	17	41825057-41836260	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Spermatocytes: 131.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"A549: 39.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA030786, HPA057095"	Approved					NA	NA			"Cluster 30: Non-specific - Translation"	"Cluster 35: Non-specific - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA030786: AB_10602716, HPA057095: AB_2683333"	"unprognostic (3.90e-2)"	"unprognostic (5.75e-2)"	"unprognostic (8.87e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.21e-1)"	"prognostic unfavorable (8.11e-5)"	"unprognostic (3.40e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.31e-1)"	"prognostic favorable (2.67e-4)"	"unprognostic (3.07e-1)"	"unprognostic (7.17e-3)"	"unprognostic (2.36e-2)"	"unprognostic (4.80e-3)"	"unprognostic (7.14e-3)"	"unprognostic (1.42e-2)"	7.9	7.6	12.4	1.5	12.8	1.2	7.6	15.5	13.4	7.6	10.8	12.9	1.9	7.0	3.3	6.3	7.0	3.2	7.1	13.0	12.3	11.1	8.7	6.5	2.8	10.9	11.3	7.4	11.5	2.8	9.9	3.0	10.6	9.0	1.1	3.6	7.8	4.2	6.0	4.7	6.5	4.8	10.0	5.7	8.9	9.5	11.8	0.9	13.0	5.6	1.9	8.9	6.8	12.7	8.1	39.5	7.8	12.7	8.6	6.0	3.2	9.5	8.5	12.9	14.3	34.0	2.1	9.3	5.6	6.3	8.6	8.3	8.2	9.9	4.6	5.9	19.7	4.1	21.8	17.8	10.1	0.1	4.7	5.3	5.4	17.4	6.5	4.7	7.5	13.8	3.6	2.4	8.6	18.0	8.2	5.1	5.0	7.9	4.2	6.2	13.2	7.8	3.7	10.0	6.0	3.5	13.4	13.8	4.9	6.7	6.7	6.3	7.1	5.3	5.4	9.3	9.5	2.7	5.6	4.2	4.2	0.1	8.1	1.1	2.3	0.3	1.8	0.5	2.5	1.8	2.4	1.8	2.4	2.5	1.9	2.1	1.3	0.7	0.4	1.3	0.4	2.0	12.4	12.8	15.5	13.4	13.0	12.3	10.9	11.3	10.6	10.0	11.8	12.7	24.8	9.6	17.2	15.0	16.9	18.1	58.7	47.3	33.6	33.8	45.1	61.1	13.6	22.8	16.6	29.5	18.8	39.0	8.7	5.1	101.8	51.6	99.8	10.9	26.8	29.1	39.4	2.5	14.2	41.6	56.2	35.2	14.3	12.1	11.4	40.1	26.7	24.0	13.4	116.1	15.5	13.2	32.6	13.2	18.5	121.6	32.3	11.7	35.6	6.5	5.8	42.4	6.2	13.0	7.2	39.1	9.8	30.5	15.5	78.7	1.4	65.1	12.7	36.5	39.5	31.1	49.3	131.8	30.0	19.8	17.2	31.2	13.8	23.7	15.2	44.6
NT5E	"CALJA, CD73, eN, eNT, NT5"	ENSG00000135318	"5'-nucleotidase ecto"	P21589	6	85449584-85495791	"CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 112.6;retina: 94.4"	"Cell type enhanced"	"Detected in many"		"Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive B-cell: 33.0;naive CD8 T-cell: 30.7"	"Group enriched"	"Detected in many"	41	"B-cells: 33.0;T-cells: 30.7"	"Cell line enhanced"	"Detected in many"		"hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA017357	Approved		Supported	"Nucleoplasm,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA		3000000	"Cluster 21: B-cells - Adaptive immune response"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"HPA017357: AB_1846330"	"unprognostic (1.92e-2)"	"unprognostic (4.44e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.57e-3)"	"unprognostic (9.33e-2)"	"unprognostic (1.82e-3)"	"unprognostic (1.20e-2)"	"prognostic unfavorable (6.66e-4)"	"unprognostic (5.45e-2)"	"unprognostic (1.80e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (1.39e-1)"	"unprognostic (3.11e-2)"	"prognostic unfavorable (1.02e-4)"	"unprognostic (3.49e-2)"	"unprognostic (2.26e-1)"	"unprognostic (2.78e-1)"	20.7	6.0	9.8	11.9	11.9	0.6	14.1	11.2	10.7	112.6	14.9	29.4	40.1	49.4	6.3	8.6	20.7	17.2	8.7	8.5	11.3	17.2	54.8	6.8	9.6	11.7	14.1	39.3	1.8	1.8	11.8	25.3	13.0	13.3	31.9	94.4	6.6	34.2	2.1	6.4	20.9	73.9	14.7	13.0	8.1	10.4	12.7	5.2	23.7	9.8	11.3	15.8	28.5	12.1	48.9	26.0	42.9	0.8	95.1	302.4	0.4	306.1	332.7	147.5	275.2	0.4	469.6	0.0	107.3	270.2	379.0	24.5	0.1	308.0	348.8	0.8	0.1	0.1	7.3	6.0	47.5	0.2	0.7	77.4	3.7	302.0	191.3	807.8	124.9	0.3	0.3	1.4	934.3	8.3	0.0	0.2	0.8	8.2	34.6	1.5	9.5	1.3	323.1	21.8	0.3	5.5	3.8	18.8	104.9	2.2	0.4	8.3	546.2	120.6	0.9	152.9	506.8	22.7	15.3	0.5	821.7	0.4	385.3	0.0	0.0	0.5	3.7	0.0	6.4	23.7	4.2	11.7	0.0	33.0	4.1	30.7	0.5	0.7	0.0	0.1	1.7	6.4	9.8	11.9	11.2	10.7	8.5	11.3	11.7	14.1	13.0	14.7	12.7	12.1	6.4	0.0	5.8	36.9	21.6	5.2	1.7	6.1	2.8	4.4	1.2	0.3	1.7	27.1	4.8	1.8	10.4	0.6	2.2	49.2	3.9	3.8	0.6	19.3	20.8	20.5	0.0	0.0	1.6	4.1	2.5	39.4	11.2	58.0	0.0	0.1	49.6	33.7	1.3	0.0	2.1	27.7	0.0	3.5	8.2	1.3	13.1	2.1	7.2	11.2	0.5	9.1	0.0	61.3	0.7	124.8	46.0	25.6	3.6	1.5	8.3	27.6	4.8	81.6	0.0	3.3	9.6	0.0	0.3	0.6	4.8	15.2	5.0	0.1	18.0	9.6
NT5M	"dNT-2, dNT2, mdN"	ENSG00000205309	"5',3'-nucleotidase, mitochondrial"	Q9NPB1	17	17303335-17347663	"Metabolic proteins, Predicted intracellular proteins"	"Nucleotide metabolism"	Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skeletal muscle: 13.3"	"Cell type enhanced"	"Detected in many"		"Distal tubular cells: 17.6;Erythroid cells: 31.2;Horizontal cells: 16.8;Inhibitory neurons: 13.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"eosinophil: 1.3"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"JURKAT: 8.5;RPMI-8226: 6.3;U-266/70: 9.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA043777	Uncertain					NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 47: Non-specific - Unknown function"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 6: Erythroid cells - Oxygen transport"			"HPA043777: AB_10962842"	"unprognostic (5.70e-2)"	"unprognostic (3.20e-2)"	"unprognostic (1.06e-2)"	"unprognostic (2.59e-2)"	"unprognostic (8.61e-3)"	"unprognostic (1.24e-1)"	"unprognostic (1.60e-1)"	"unprognostic (1.61e-1)"	"unprognostic (2.48e-1)"	"prognostic favorable (8.42e-5)"	"unprognostic (4.28e-5)"	"unprognostic (2.27e-1)"	"unprognostic (4.93e-2)"	"unprognostic (3.89e-2)"	"unprognostic (1.05e-1)"	"unprognostic (7.93e-2)"	"unprognostic (1.05e-2)"	1.1	0.6	6.3	0.2	5.9	4.7	0.9	6.4	7.9	2.2	4.6	2.8	0.4	2.1	0.4	0.9	1.6	0.4	7.1	5.6	5.8	2.2	1.0	0.8	0.3	6.2	6.1	1.9	1.1	1.8	4.5	0.2	6.4	1.8	0.1	0.5	0.8	0.7	13.3	0.8	0.8	0.4	5.7	0.9	1.1	6.8	7.3	1.1	0.8	4.6	0.2	2.0	1.1	6.4	0.3	0.7	0.3	2.9	1.7	1.9	1.2	0.6	0.2	0.2	0.4	0.0	0.2	3.3	1.8	0.0	0.5	0.0	0.1	0.1	0.0	2.9	1.8	2.3	0.1	0.3	1.7	0.6	4.3	1.4	1.5	0.3	1.1	0.6	0.0	8.5	2.0	0.0	0.0	0.8	2.8	2.6	1.8	1.0	2.5	2.1	0.2	6.3	1.0	0.0	3.6	5.9	1.0	0.1	2.6	2.1	1.0	0.9	0.0	0.9	1.0	0.2	0.8	9.3	1.3	0.5	0.5	0.4	2.4	0.0	0.0	1.3	0.0	0.0	0.4	0.0	0.0	0.5	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	6.3	5.9	6.4	7.9	5.6	5.8	6.2	6.1	6.4	5.7	7.3	6.4	1.1	0.0	0.5	11.1	0.5	1.7	2.1	0.1	2.2	5.5	3.4	6.1	7.9	1.5	0.6	9.2	2.1	1.0	2.6	0.4	17.6	0.3	0.9	0.3	3.3	1.7	1.2	31.2	7.6	0.6	1.2	2.5	1.1	0.9	0.0	5.2	0.7	1.3	1.5	16.8	13.2	0.8	0.0	0.8	0.6	4.4	0.6	3.4	0.0	3.7	0.3	4.7	2.1	4.0	5.4	0.0	0.1	1.2	2.3	3.2	0.1	2.9	0.0	1.8	0.0	7.4	1.8	1.5	6.0	1.8	0.4	0.5	2.3	3.2	0.5	1.3
NUDT5	"hYSAH1, YSA1H"	ENSG00000165609	"Nudix hydrolase 5"	Q9UKK9	10	12165330-12196144	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Hydrolase, RNA-binding, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019827	Approved		Approved	Nucleoplasm,Vesicles,Centrosome		NA	NA		1500000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 64: Macrophages - Immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Vesicles	"Nucleoplasm, Centrosome"	"HPA019827: AB_1854704"	"unprognostic (2.08e-2)"	"unprognostic (2.10e-1)"	"unprognostic (1.61e-1)"	"unprognostic (2.09e-1)"	"unprognostic (3.77e-3)"	"unprognostic (4.91e-2)"	"unprognostic (2.54e-2)"	"unprognostic (4.60e-2)"	"unprognostic (1.32e-1)"	"unprognostic (6.39e-3)"	"unprognostic (2.06e-1)"	"unprognostic (9.97e-2)"	"prognostic unfavorable (7.14e-12)"	"unprognostic (1.61e-1)"	"unprognostic (1.33e-1)"	"unprognostic (3.12e-2)"	"unprognostic (3.68e-2)"	35.1	32.4	23.0	30.6	26.4	24.1	26.7	27.5	30.5	24.6	29.5	32.0	27.5	14.3	23.7	40.7	24.6	18.4	14.9	23.4	26.0	36.3	88.8	26.0	39.3	27.3	24.9	18.0	25.9	33.1	35.5	31.1	27.4	21.0	36.0	27.4	25.1	14.0	6.2	33.2	25.4	17.6	25.0	34.2	22.6	13.1	25.4	53.5	27.8	7.6	47.4	28.9	27.8	31.8	136.4	98.0	114.6	107.1	107.5	105.6	100.8	96.9	61.5	111.9	119.1	142.5	125.9	134.2	82.4	79.2	70.0	133.1	162.0	150.6	102.1	110.8	160.8	111.9	114.3	209.3	112.0	77.1	75.2	111.7	88.4	122.3	61.7	86.3	144.9	209.4	153.5	88.9	103.2	123.8	143.5	87.0	100.4	215.0	60.1	128.0	42.4	157.2	106.0	46.1	56.6	82.3	117.4	90.8	142.2	132.0	155.9	77.9	91.6	47.0	90.6	134.3	121.9	74.3	141.6	179.3	99.7	97.3	36.0	29.6	60.8	115.2	69.9	65.7	80.4	72.7	73.9	82.6	87.6	64.6	50.4	68.4	163.8	57.4	52.2	149.2	123.4	71.6	23.0	26.4	27.5	30.5	23.4	26.0	27.3	24.9	27.4	25.0	25.4	31.8	42.1	25.6	55.1	23.2	43.8	43.0	57.8	121.2	28.5	21.1	28.6	30.7	4.5	32.9	72.3	23.9	16.7	82.6	49.8	35.0	74.3	82.2	35.3	61.1	44.4	42.6	38.3	43.5	34.6	82.9	150.6	40.3	33.1	31.9	31.7	41.4	41.7	131.8	128.7	21.9	38.2	41.2	79.3	41.8	32.2	11.7	39.4	39.7	30.2	12.2	85.0	37.4	62.8	34.2	41.2	73.8	35.2	29.0	66.1	33.7	52.6	130.6	103.9	25.5	32.9	21.2	40.1	20.2	33.6	52.4	60.5	58.1	49.7	54.4	57.4	46.9
NUDT9	MGC3037	ENSG00000170502	"Nudix hydrolase 9"	Q9BW91	4	87422573-87459455	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPTEC TERT1: 160.7"	"Low region specificity"	"Detected in all"							"HPA036917, HPA044866, HPA078535"	Approved		Approved	"Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria"	"Intracellular and membrane"	NA	NA		9900	"Cluster 27: Non-specific - Gene expression"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	"Nuclear bodies, Mitochondria"	"Nuclear membrane, Cell Junctions"	"HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885"	"unprognostic (7.22e-2)"	"unprognostic (2.59e-2)"	"unprognostic (1.45e-2)"	"prognostic favorable (7.43e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.33e-1)"	"unprognostic (3.47e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.09e-2)"	"unprognostic (4.23e-1)"	"prognostic favorable (8.00e-11)"	"unprognostic (1.21e-1)"	"unprognostic (1.99e-1)"	"unprognostic (1.19e-1)"	"unprognostic (5.77e-3)"	23.6	36.1	20.8	16.2	21.4	6.7	19.7	25.5	38.5	27.6	39.1	27.0	42.6	24.8	32.2	19.6	24.9	16.2	28.8	21.9	24.7	40.4	46.6	23.0	13.7	21.0	20.5	26.7	67.6	55.3	29.1	19.9	21.9	30.4	27.1	20.1	28.1	23.8	42.1	16.6	40.3	23.8	19.6	14.7	22.3	22.5	22.1	13.4	28.8	45.0	14.8	22.4	24.3	26.0	30.8	25.6	34.0	19.8	67.6	39.6	26.0	59.8	35.6	21.3	21.1	17.1	53.1	47.6	58.9	47.6	41.0	21.1	32.1	38.1	33.2	34.5	24.0	13.4	34.5	31.8	42.4	25.6	21.2	41.5	52.4	25.6	22.6	45.5	41.6	13.7	40.3	30.0	38.7	33.4	39.1	23.2	29.1	68.5	12.0	45.0	31.8	27.0	160.7	24.2	41.3	28.7	37.6	63.0	30.8	44.5	36.8	38.2	43.7	34.7	34.3	25.8	27.8	21.5	18.7	37.9	51.3	21.9	48.2	1.6	17.9	5.9	19.1	21.2	18.2	22.2	18.5	19.5	21.4	18.8	22.5	26.0	1.8	15.6	24.0	20.6	19.0	16.0	20.8	21.4	25.5	38.5	21.9	24.7	21.0	20.5	21.9	19.6	22.1	26.0	32.6	67.3	44.8	20.2	14.9	9.9	40.4	45.0	9.6	15.3	11.3	13.1	40.9	30.0	55.0	23.9	27.1	33.2	13.1	21.0	41.1	44.7	28.6	26.0	26.2	25.8	16.8	6.7	21.7	36.5	32.5	29.4	8.6	27.0	20.8	23.3	18.2	47.5	33.2	6.7	24.0	18.0	40.7	12.7	11.0	11.5	25.4	14.7	10.6	20.6	16.4	26.8	8.2	18.6	24.8	29.4	37.0	26.7	15.8	32.9	55.7	56.2	41.0	18.6	26.3	36.9	23.7	44.5	23.6	15.7	9.5	37.6	12.1	29.8	24.9	27.3
PAICS	"ADE2H1, AIRC, PAIS"	ENSG00000128050	"Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase"	P22234	4	56435741-56464578	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	"Decarboxylase, Ligase, Lyase, Multifunctional enzyme"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 157.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA035895, HPA041538"	Approved		Approved	Cytosol		Yes	No		490000	"Cluster 30: Non-specific - Translation"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"HPA035895: AB_10669660, HPA041538: AB_2677540"	"unprognostic (2.59e-3)"	"unprognostic (7.90e-3)"	"unprognostic (3.84e-3)"	"unprognostic (2.88e-2)"	"unprognostic (9.85e-2)"	"unprognostic (2.82e-3)"	"prognostic unfavorable (1.50e-4)"	"unprognostic (8.07e-3)"	"unprognostic (1.23e-2)"	"prognostic favorable (8.44e-4)"	"unprognostic (1.48e-3)"	"unprognostic (2.05e-1)"	"prognostic unfavorable (5.85e-5)"	"unprognostic (7.11e-2)"	"unprognostic (1.67e-1)"	"prognostic unfavorable (2.41e-4)"	"unprognostic (2.16e-1)"	24.5	40.2	22.7	40.1	26.7	46.8	54.6	28.3	25.0	29.3	21.6	42.8	32.1	29.7	22.1	36.3	35.4	17.8	19.7	20.3	27.8	42.7	109.7	14.1	51.3	26.0	30.1	30.7	21.7	39.5	17.7	45.9	26.1	31.0	54.7	30.4	26.4	25.8	32.4	37.6	30.8	35.7	25.6	18.3	20.7	29.5	26.8	56.4	32.4	24.1	64.5	37.4	25.4	27.2	239.3	175.3	354.3	220.6	74.3	166.1	304.0	201.7	145.1	282.5	276.0	280.5	275.7	548.0	228.3	136.0	154.1	143.6	565.5	293.0	480.8	110.4	198.8	298.7	259.5	313.4	141.8	537.1	127.6	141.9	207.9	301.0	225.0	155.7	235.4	308.6	524.7	198.5	246.8	159.3	621.5	267.2	407.5	454.8	216.5	496.2	151.7	361.5	268.4	164.5	378.8	226.4	198.6	273.7	124.3	287.2	181.2	169.8	127.7	222.6	290.1	221.8	419.0	139.1	128.2	571.1	234.8	385.2	251.0	6.0	5.2	0.4	5.2	8.7	15.0	17.8	14.4	9.2	15.3	11.0	17.4	15.5	1.1	15.9	6.9	17.0	11.2	8.7	22.7	26.7	28.3	25.0	20.3	27.8	26.0	30.1	26.1	25.6	26.8	27.2	16.4	22.4	22.9	17.0	35.7	56.6	71.9	66.0	54.1	27.4	35.8	37.5	23.3	50.1	32.3	33.1	6.2	134.4	15.3	20.5	37.2	45.0	69.4	15.2	49.1	25.1	24.7	80.8	9.1	26.3	157.5	34.2	15.3	23.3	21.0	69.1	13.2	78.7	51.5	28.6	14.6	41.0	34.6	16.1	17.2	10.6	29.8	16.1	17.8	6.5	20.2	14.0	6.2	13.0	12.2	27.4	18.6	23.3	48.1	81.7	15.9	47.7	17.9	24.6	0.0	31.3	29.2	40.0	50.3	53.1	50.4	54.6	16.8	66.4	69.7	48.9
PDE10A		ENSG00000112541	"Phosphodiesterase 10A"	Q9Y233	6	165327287-165988078	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Hydrolase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	11	"brain: 67.2"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in many"	6	"basal ganglia: 67.2"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0"	"Region enriched"	"Detected in all"	11	"basal ganglia: 350.1"	"Region enriched"	"Detected in all"	5	"basal ganglia: 194.1"	"CAB045998, HPA047200"	Supported					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB045998: AB_2162589, HPA047200: AB_2679981"	"unprognostic (1.02e-1)"	"unprognostic (3.63e-2)"	"unprognostic (3.58e-2)"	"unprognostic (2.91e-1)"	"unprognostic (1.20e-1)"	"unprognostic (1.25e-1)"	"unprognostic (1.76e-1)"	"unprognostic (1.23e-1)"	"unprognostic (9.36e-2)"	"unprognostic (6.03e-2)"	"unprognostic (3.79e-2)"	"unprognostic (9.24e-2)"	"prognostic unfavorable (4.44e-7)"	"unprognostic (3.59e-3)"	"unprognostic (2.37e-2)"	"unprognostic (3.44e-2)"	"unprognostic (5.90e-3)"	2.6	1.3	3.1	0.8	67.2	0.0	2.3	5.5	10.7	1.3	0.0	1.0	0.2	2.0	2.4	0.4	2.4	1.5	3.6	2.1	2.5	3.8	0.3	1.0	0.5	1.6	2.3	2.3	0.5	0.5	2.7	2.5	0.9	1.7	0.2	1.9	0.4	1.7	0.4	0.3	0.7	2.1	0.5	1.4	1.1	3.4	9.6	0.3	6.0	0.5	0.4	3.2	0.9	0.1	0.0	2.4	5.5	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	6.3	0.8	0.0	0.0	0.0	3.8	0.1	2.2	0.0	0.0	0.1	3.9	0.0	9.0	0.0	0.4	0.0	0.0	0.0	0.0	0.6	0.0	0.0	5.5	0.0	0.0	0.0	12.5	0.3	0.9	0.0	1.1	0.0	4.7	1.5	5.8	0.0	5.9	6.9	1.8	8.1	0.0	0.0	0.4	0.7	0.0	0.0	11.3	0.1	7.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	3.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.1	67.2	5.5	10.7	2.1	2.5	1.6	2.3	0.9	0.5	9.6	0.1	13.8	0.0	0.0	10.4	0.1	0.4	3.3	0.4	0.0	7.2	0.3	0.3	7.3	0.0	1.2	5.5	2.1	7.8	0.0	0.0	3.9	2.0	14.3	0.2	1.7	13.4	0.0	0.0	204.7	0.0	6.1	6.6	1.1	0.4	1.3	0.1	7.9	0.0	0.8	16.8	209.6	0.0	0.0	0.0	0.0	14.9	0.0	0.2	1.8	89.0	0.0	12.6	0.0	48.7	51.8	0.1	0.0	0.4	0.0	17.9	0.0	7.2	0.9	1.1	0.0	12.4	5.0	8.8	2.1	0.1	0.3	2.9	0.1	1.6	0.1	6.9
PDE11A		ENSG00000128655	"Phosphodiesterase 11A"	Q9HCR9	2	177623244-178072777	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Hydrolase"	"Cushing syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 6.3;parathyroid gland: 9.8"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9"	"Cancer enhanced"	"Detected in some"		"prostate cancer: 1.7"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8"									HPA034560	Approved				"Intracellular and membrane"	NA	NA				"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 25: Spermatids - Spermatogenesis"			"HPA034560: AB_10602140"	"unprognostic (1.02e-1)"	"unprognostic (4.73e-2)"	"unprognostic (1.02e-1)"	"unprognostic (9.61e-3)"	"unprognostic (2.34e-2)"	"unprognostic (1.43e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.28e-2)"	"unprognostic (2.23e-1)"	"unprognostic (3.91e-1)"	"unprognostic (9.95e-2)"	"unprognostic (2.80e-2)"	"unprognostic (5.06e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.75e-1)"	"unprognostic (4.11e-4)"	"unprognostic (1.64e-3)"	2.3	0.3	0.8	0.1	2.0	0.2	1.7	1.9	1.2	0.6	0.6	0.5	0.8	1.2	0.4	0.0	0.3	0.4	0.3	0.6	2.1	0.5	6.3	0.0	0.0	2.5	2.1	0.4	1.1	9.8	0.9	0.0	2.7	5.2	0.4	1.4	1.4	0.8	4.4	0.1	0.5	1.1	3.7	0.1	0.4	2.8	1.9	0.1	1.3	1.3	0.0	0.0	0.1	3.2	0.0	0.4	0.2	0.1	0.0	0.0	0.0	1.1	0.2	0.0	0.3	0.2	1.6	0.0	0.6	2.4	0.3	0.1	1.4	0.0	0.0	0.0	0.9	1.1	0.1	2.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.9	0.0	0.2	0.2	0.4	0.1	0.6	0.0	0.3	0.2	0.0	0.2	0.0	0.5	0.0	0.3	0.7	0.0	0.1	0.1	0.2	0.1	0.0	0.0	0.1	0.3	0.0	0.1	0.2	0.0	0.0	0.4	0.0	0.1	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.2	0.1	0.1	0.1	0.0	0.0	0.8	2.0	1.9	1.2	0.6	2.1	2.5	2.1	2.7	3.7	1.9	3.2	0.1	0.0	0.0	2.3	0.2	0.6	1.4	0.1	0.0	1.7	4.2	0.8	0.0	1.5	0.1	0.0	0.0	0.1	0.3	0.8	0.0	0.8	37.0	0.3	0.2	0.6	6.7	2.7	1.6	6.7	0.0	0.6	0.0	0.2	0.0	0.0	1.4	11.1	0.1	0.0	8.2	0.9	6.1	1.2	2.1	46.4	1.5	0.3	0.0	0.0	0.0	4.7	0.0	6.0	14.9	2.3	0.0	0.7	0.0	5.4	0.6	1.3	0.1	1.0	0.0	2.0	0.6	6.8	6.9	0.0	1.3	0.3	0.3	0.3	1.3	1.0
PDE1A		ENSG00000115252	"Phosphodiesterase 1A"	P54750	2	182140036-182523192	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Calmodulin-binding, Hydrolase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"kidney: 46.6;thyroid gland: 45.8"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 396.3;Excitatory neurons: 764.9;Late spermatids: 592.1;Oligodendrocytes: 1178.0"	"Cancer enhanced"	"Detected in many"		"thyroid cancer: 13.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"ASC diff: 37.2;HHSteC: 22.0;HSkMC: 47.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA022151	Approved		Approved	Nucleoplasm		NA	NA				"Cluster 43: Testis - Unknown function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	Nucleoplasm		"HPA022151: AB_1855118"	"unprognostic (3.63e-1)"	"unprognostic (7.21e-2)"	"unprognostic (1.32e-1)"	"unprognostic (8.61e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (3.84e-1)"	"unprognostic (3.82e-1)"	"unprognostic (1.02e-1)"	"unprognostic (5.38e-2)"	"unprognostic (2.78e-1)"	"unprognostic (2.86e-1)"	"unprognostic (5.55e-3)"	"unprognostic (2.50e-3)"	"unprognostic (5.96e-2)"	"unprognostic (1.37e-1)"	"unprognostic (1.40e-3)"	10.5	4.4	16.9	4.6	20.4	0.0	5.0	35.5	23.4	17.2	2.4	11.8	3.0	8.7	8.0	5.6	10.3	23.7	15.6	30.3	8.4	46.6	3.9	3.6	2.1	2.6	4.2	10.9	2.1	2.2	2.7	1.2	5.4	3.6	6.7	1.4	2.0	5.4	2.8	2.2	5.7	12.9	3.7	3.1	5.6	35.6	16.5	8.4	45.8	5.0	0.9	9.7	9.8	18.2	0.0	0.2	3.9	0.0	37.2	3.1	0.1	0.3	0.4	0.1	0.0	0.0	0.1	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.1	0.1	4.7	0.0	5.1	0.0	22.0	0.0	0.0	47.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	7.5	1.1	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	3.7	0.0	5.4	0.1	0.1	0.2	0.2	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	16.9	20.4	35.5	23.4	30.3	8.4	2.6	4.2	5.4	3.7	16.5	18.2	6.7	0.0	2.6	15.3	0.0	1.3	2.0	0.1	8.0	20.0	0.3	0.3	5.9	1.5	1.4	27.6	0.0	0.1	0.0	0.1	185.9	0.5	396.3	0.3	0.4	8.9	0.0	0.0	764.9	0.4	0.0	18.6	0.0	0.8	0.0	0.1	5.0	0.0	0.1	0.0	185.8	1.0	0.0	0.0	1.8	592.1	14.9	0.4	0.0	30.0	0.0	0.3	0.0	18.1	1178.0	0.2	0.1	8.2	0.2	2.6	0.1	1.5	0.0	1.2	52.6	21.0	45.1	9.1	4.9	1.0	1.3	0.0	0.2	7.6	0.1	0.7
PDE1B	PDES1B	ENSG00000123360	"Phosphodiesterase 1B"	Q01064	12	54549601-54579239	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Calmodulin-binding, Hydrolase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	8	"brain: 76.9"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 18.6;Inhibitory neurons: 10.2;Kupffer cells: 13.0;Macrophages: 9.4;Sertoli cells: 13.1;Smooth muscle cells: 13.7"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in many"	6	"basal ganglia: 76.9"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HDLM-2: 12.7;HMC-1: 14.9;NB-4: 10.7;THP-1: 9.0;U-937: 7.2"	"Region enriched"	"Detected in all"	6	"basal ganglia: 999.4"	"Region enriched"	"Detected in all"	7	"basal ganglia: 228.7"	HPA018492	Enhanced					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 48: Smooth muscle cells - ECM organization"			"HPA018492: AB_1855119"	"unprognostic (2.90e-1)"	"unprognostic (1.51e-1)"	"unprognostic (7.67e-4)"	"unprognostic (5.63e-3)"	"unprognostic (7.02e-2)"	"unprognostic (7.51e-2)"	"unprognostic (1.97e-1)"	"unprognostic (9.39e-2)"	"unprognostic (1.14e-1)"	"unprognostic (5.11e-2)"	"unprognostic (3.84e-3)"	"unprognostic (2.70e-2)"	"prognostic unfavorable (4.77e-6)"	"unprognostic (6.64e-4)"	"unprognostic (2.14e-1)"	"unprognostic (3.09e-1)"	"unprognostic (2.83e-2)"	9.1	1.1	8.4	4.0	76.9	4.8	4.6	0.0	13.7	2.0	0.0	7.4	1.0	2.7	1.8	1.7	2.0	2.2	1.4	6.3	0.1	0.8	1.0	2.3	1.3	0.0	0.0	8.6	0.4	6.1	0.3	0.2	0.0	1.3	1.0	0.4	1.0	1.4	0.6	1.4	3.4	4.0	0.0	4.0	3.3	0.7	2.4	0.9	2.0	1.0	0.8	8.7	1.5	4.9	0.0	0.0	0.6	0.0	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	3.2	0.1	0.0	0.0	0.0	2.1	0.0	0.0	12.7	0.6	4.3	0.0	0.0	0.0	5.5	14.9	0.7	0.0	0.0	0.0	0.0	0.0	5.5	0.0	2.3	0.0	0.0	0.5	10.7	3.5	0.0	0.0	2.0	0.0	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	9.0	0.0	0.0	0.3	0.0	0.0	0.1	0.2	2.5	0.0	7.2	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	8.4	76.9	0.0	13.7	6.3	0.1	0.0	0.0	0.0	0.0	2.4	4.9	2.3	0.0	1.1	1.6	1.8	1.0	0.2	0.0	0.6	2.7	0.2	0.6	3.6	0.0	0.6	3.7	0.0	0.1	1.4	0.0	0.0	0.0	6.3	0.1	0.0	0.8	1.8	3.6	18.6	0.0	0.0	1.5	0.0	0.0	0.0	4.4	0.0	0.3	8.5	5.0	10.2	0.0	0.0	13.0	2.5	4.9	2.1	9.4	0.0	2.8	6.7	0.1	4.1	1.0	0.9	0.0	0.0	3.0	2.6	0.4	0.0	0.0	0.0	0.2	13.1	0.6	13.7	0.8	0.6	0.2	0.4	0.3	2.8	0.4	0.1	0.1
PDE1C	Hcam3	ENSG00000154678	"Phosphodiesterase 1C"	Q14123	7	31751179-32428131	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		"Calmodulin-binding, Hydrolase"	"Deafness, Disease variant, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"brain: 68.9;heart muscle: 58.5"	"Cell type enriched"	"Detected in many"	5	"Oligodendrocytes: 1071.4"	"Cancer enhanced"	"Detected in some"		"glioma: 1.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA052375			Approved	Nucleoplasm		NA	NA				"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Nucleoplasm		"HPA052375: AB_2681802"	"unprognostic (1.29e-2)"	"unprognostic (2.20e-5)"	"unprognostic (1.68e-2)"	"unprognostic (1.20e-3)"	"unprognostic (2.29e-1)"	"unprognostic (5.65e-2)"	"unprognostic (4.06e-3)"	"unprognostic (2.75e-1)"	"unprognostic (6.79e-3)"	"unprognostic (6.49e-2)"	"unprognostic (3.88e-5)"	"unprognostic (7.03e-2)"	"unprognostic (3.09e-3)"	"unprognostic (5.76e-2)"	"unprognostic (5.80e-2)"	"unprognostic (1.49e-1)"	"unprognostic (1.06e-3)"	2.4	1.8	19.2	2.5	43.0	0.0	4.3	21.4	39.9	0.7	0.0	3.0	1.4	2.4	6.0	6.4	10.5	1.5	58.5	18.9	24.2	4.2	0.1	4.9	0.6	29.4	27.9	3.8	2.6	0.3	1.3	3.2	27.7	2.0	1.8	7.4	1.8	3.2	0.6	0.4	3.3	5.0	16.4	0.6	4.0	3.8	28.6	1.6	3.1	4.0	0.1	9.8	1.4	68.9	0.3	5.8	15.5	0.0	0.6	0.4	0.2	44.4	18.3	20.8	17.1	0.0	0.0	0.0	0.2	148.3	0.0	1.2	0.0	0.0	27.1	0.0	0.0	1.3	1.4	0.0	0.1	0.0	31.9	1.9	0.0	4.3	0.2	44.9	7.1	0.0	0.1	0.1	1.7	0.0	0.1	0.0	0.0	0.0	13.7	0.0	0.0	0.0	22.5	0.0	6.8	0.0	0.0	0.0	0.0	1.3	0.0	0.3	0.2	22.8	8.6	0.4	77.9	0.4	0.0	0.0	2.4	0.5	105.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	19.2	43.0	21.4	39.9	18.9	24.2	29.4	27.9	27.7	16.4	28.6	68.9	1.2	0.0	0.0	7.5	0.1	0.0	0.7	0.1	1.2	69.5	2.8	17.1	136.0	0.0	0.7	1.8	52.1	0.0	0.1	0.0	0.0	4.8	53.4	0.2	0.1	3.9	0.0	0.0	70.8	0.4	0.0	8.7	0.0	0.4	8.8	0.2	0.0	0.0	0.1	3.3	169.2	0.0	59.0	0.0	0.2	50.3	0.3	0.5	0.0	15.9	0.0	0.9	0.0	196.6	1071.4	0.2	0.0	0.4	0.1	0.2	0.0	0.0	2.2	4.7	0.0	0.9	9.4	1.3	1.2	0.2	0.0	0.0	0.1	1.2	0.0	0.0
PDE2A		ENSG00000186642	"Phosphodiesterase 2A"	O00408	11	72576141-72674591	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 197.0"	"Group enriched"	"Detected in many"	6	"Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3"	"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"B-cells: 2.8;T-cells: 7.3"	"Cell line enriched"	"Detected in some"	8	"HeLa: 513.6"	"Low region specificity"	"Detected in some"			"Group enriched"	"Detected in all"	5	"amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0"	"CAB009752, HPA031192"	Enhanced		Supported	Cytosol		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 20: HeLa - Mitochondria"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Cytosol		"CAB009752: AB_2268159, HPA031192: AB_2673781"	"unprognostic (1.92e-1)"	"unprognostic (1.52e-3)"	"unprognostic (4.58e-2)"	"unprognostic (1.49e-1)"	"unprognostic (1.26e-1)"	"unprognostic (2.50e-1)"	"prognostic favorable (1.76e-6)"	"unprognostic (3.06e-2)"	"unprognostic (1.35e-1)"	"unprognostic (3.01e-3)"	"unprognostic (3.13e-3)"	"unprognostic (1.50e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.85e-3)"	"unprognostic (6.31e-2)"	"unprognostic (7.72e-2)"	"unprognostic (7.96e-4)"	89.2	44.1	75.1	5.1	84.7	4.7	83.6	0.0	102.1	38.1	0.0	34.6	6.0	27.2	8.3	18.6	39.3	22.7	41.1	84.4	7.0	32.5	19.4	12.6	6.7	6.4	5.1	11.6	6.9	5.5	11.8	12.0	10.1	20.7	8.9	3.0	9.2	10.7	16.8	18.1	18.7	18.5	0.0	197.0	17.1	7.4	17.9	3.8	24.1	28.9	3.5	28.8	27.1	48.3	0.3	0.2	0.7	0.2	0.2	0.1	0.3	0.1	0.2	0.2	0.4	0.4	2.5	0.8	12.2	0.2	1.9	0.2	0.9	0.1	0.1	0.1	0.1	0.0	513.6	0.8	0.9	0.0	7.8	0.1	1.1	2.7	20.5	1.1	11.3	0.5	0.8	0.9	0.1	0.0	0.2	0.2	7.4	0.2	14.0	0.0	0.2	1.4	0.1	0.3	44.5	2.4	0.4	0.2	2.2	0.7	0.3	0.1	65.2	0.1	9.4	3.5	0.4	0.4	0.2	0.1	3.9	0.1	0.6	0.0	0.6	0.0	7.3	0.8	4.2	2.8	4.3	4.3	1.0	1.8	2.7	2.3	0.1	0.0	0.4	0.0	1.8	1.5	75.1	84.7	0.0	102.1	84.4	7.0	6.4	5.1	10.1	0.0	17.9	48.3	114.9	0.0	0.5	2.0	0.7	2.5	0.1	0.0	0.0	4.9	0.6	1.0	7.8	0.0	0.0	0.0	0.0	0.0	1.6	0.2	0.0	0.0	0.6	0.0	0.1	58.5	34.4	5.3	70.1	0.0	0.3	2.1	0.0	0.1	1.3	0.1	118.2	2.1	0.5	1.7	35.6	1.2	0.0	9.4	8.2	2.5	0.3	4.9	1.8	11.2	0.0	0.0	0.0	9.0	5.7	0.1	0.0	0.4	1.5	0.1	0.0	0.1	0.0	0.4	0.0	1.8	6.6	4.8	2.5	0.5	2.8	0.0	0.6	0.2	0.1	0.3
PDE3A	CGI-PDE	ENSG00000172572	"Phosphodiesterase 3A"	Q14432	12	20368537-20688583	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins"		Hydrolase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"heart muscle: 43.4"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9"	"Low region specificity"	"Detected in many"			"Region enhanced"	"Detected in many"		"cerebellum: 18.8"	"HPA014492, HPA074258"	Approved		Approved	"Plasma membrane"		NA	NA		37000000		"Cluster 46: Fibroblasts - ECM organization"	"Cluster 20: HeLa - Mitochondria"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Plasma membrane"		"HPA014492: AB_1855120, HPA074258: "	"unprognostic (2.59e-2)"	"unprognostic (2.94e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.23e-1)"	"unprognostic (2.27e-1)"	"unprognostic (1.21e-1)"	"unprognostic (3.50e-2)"	"unprognostic (1.67e-2)"	"unprognostic (8.14e-2)"	"unprognostic (1.49e-1)"	"unprognostic (4.25e-1)"	"unprognostic (3.37e-1)"	"prognostic unfavorable (1.72e-6)"	"unprognostic (5.58e-2)"	"unprognostic (5.94e-2)"	"unprognostic (4.28e-2)"	"unprognostic (2.76e-4)"	6.5	1.0	1.6	3.1	1.3	0.2	3.8	3.1	1.3	6.7	1.8	15.0	1.9	4.2	1.4	2.2	4.1	4.7	43.4	1.3	1.5	3.3	1.3	3.9	1.0	1.9	2.3	3.4	6.2	0.6	2.1	11.3	1.2	5.4	7.6	5.7	2.7	3.5	2.2	1.3	9.6	5.2	1.6	2.2	5.1	0.4	2.5	0.6	2.8	1.8	0.5	2.5	3.1	1.4	0.0	0.2	8.6	0.0	1.9	1.3	0.0	0.2	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	15.3	42.5	0.2	0.6	0.0	0.0	1.8	0.0	0.4	0.1	0.1	7.4	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.4	0.0	1.1	0.0	0.0	0.0	2.7	0.0	0.1	17.9	0.0	0.0	0.1	3.3	0.0	0.0	0.3	11.9	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.6	1.3	3.1	1.3	1.3	1.5	1.9	2.3	1.2	1.6	2.5	1.4	2.7	0.0	0.0	98.2	0.0	0.3	0.2	0.0	0.6	38.4	0.2	0.3	131.3	4.3	0.6	0.0	0.0	0.0	0.0	28.4	0.0	5.8	0.7	0.5	1.6	3.9	4.2	0.0	4.1	0.5	0.0	11.3	0.0	1.4	17.1	0.0	2.2	0.0	0.7	52.2	78.8	7.0	0.0	0.0	0.7	0.6	1.5	3.1	1.8	27.2	0.5	4.4	0.0	27.6	3.9	0.4	26.9	0.7	0.0	0.5	33.4	3.1	0.0	2.8	6.6	3.6	49.9	0.3	0.9	0.9	0.3	0.0	0.6	0.5	16.4	0.2
PDE3B	HcGIP1	ENSG00000152270	"Phosphodiesterase 3B"	Q13370	11	14643804-14872044	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins"	Angiogenesis	Hydrolase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 64.5"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 171.7;Excitatory neurons: 140.5;Inhibitory neurons: 158.0;Microglial cells: 192.0;Oligodendrocyte precursor cells: 118.6"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in all"	5	"cerebellum: 13.5"	"Low immune cell specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"granulocytes: 3.8;T-cells: 6.3"	"Cell line enhanced"	"Detected in many"		"HL-60: 23.5;Karpas-707: 25.7;THP-1: 28.4;U-266/70: 28.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056111			Approved	"Endoplasmic reticulum"		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Endoplasmic reticulum"		"HPA056111: AB_2683041"	"unprognostic (1.05e-1)"	"unprognostic (2.86e-2)"	"unprognostic (4.12e-2)"	"unprognostic (2.76e-3)"	"unprognostic (4.25e-1)"	"unprognostic (1.84e-3)"	"unprognostic (3.40e-2)"	"unprognostic (3.24e-2)"	"unprognostic (5.39e-2)"	"unprognostic (1.20e-1)"	"prognostic favorable (7.91e-4)"	"unprognostic (1.77e-1)"	"unprognostic (2.33e-2)"	"unprognostic (1.39e-2)"	"unprognostic (3.42e-1)"	"unprognostic (2.47e-1)"	"unprognostic (9.03e-3)"	64.5	1.1	1.3	12.4	2.1	10.1	12.2	13.5	2.6	3.4	0.0	25.2	2.9	0.7	0.5	2.9	0.5	3.7	4.7	1.9	2.6	3.0	25.8	10.2	14.9	2.8	1.7	0.5	8.3	0.2	4.4	7.6	1.9	8.7	10.7	0.5	14.0	1.6	0.4	0.5	6.0	1.7	2.3	8.9	2.6	9.6	2.0	7.3	0.8	2.4	7.9	8.5	1.9	2.6	0.0	2.5	5.6	9.2	10.9	0.1	2.2	0.6	0.1	0.0	0.0	8.5	0.0	0.0	0.1	0.0	2.6	0.0	8.5	0.0	0.0	0.2	18.7	0.3	13.1	17.5	3.9	23.5	0.1	0.8	0.0	0.0	0.5	0.0	0.1	6.6	20.6	25.7	0.0	0.3	4.7	11.4	7.6	3.1	4.1	11.0	2.5	17.7	0.0	1.9	8.5	15.8	2.3	14.6	5.1	2.5	0.0	28.4	0.0	0.0	1.3	0.0	0.0	28.8	9.4	0.7	0.2	4.0	1.7	0.0	0.5	2.5	1.0	0.6	2.1	0.2	3.1	2.4	0.3	0.1	6.3	5.7	3.8	0.1	1.0	0.1	3.5	1.5	1.3	2.1	13.5	2.6	1.9	2.6	2.8	1.7	1.9	2.3	2.0	2.6	1.5	16.0	8.9	171.7	6.4	0.3	0.9	0.0	0.6	1.0	0.3	0.3	11.1	0.0	6.2	1.8	0.0	1.4	26.7	11.5	1.9	0.0	19.0	0.3	5.1	4.0	1.2	12.8	140.5	5.0	2.8	9.7	7.7	0.3	36.1	0.5	4.2	64.1	7.6	0.0	158.0	13.7	0.0	13.1	3.7	13.4	1.5	15.6	0.0	192.0	10.8	6.3	8.2	118.6	5.4	1.8	22.3	9.1	28.9	3.3	0.7	2.0	3.6	0.5	0.0	3.4	3.0	48.8	19.5	0.1	0.1	2.5	60.9	0.0	9.4	1.1
PDE4A	DPDE2	ENSG00000065989	"Phosphodiesterase 4A"	P27815	19	10416773-10469630	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		Hydrolase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Langerhans cells: 190.8;Late spermatids: 197.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"HMC-1: 36.5;NB-4: 43.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017632, HPA043310, HPA076091"	Uncertain		Supported	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 47: Non-specific - Unknown function"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 25: Spermatids - Spermatogenesis"	"Plasma membrane"	Nucleoplasm	"CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775"	"unprognostic (1.29e-2)"	"unprognostic (3.98e-2)"	"unprognostic (8.91e-2)"	"unprognostic (1.82e-1)"	"unprognostic (7.00e-2)"	"unprognostic (6.84e-2)"	"unprognostic (1.54e-2)"	"unprognostic (4.39e-2)"	"unprognostic (7.91e-2)"	"unprognostic (1.52e-2)"	"unprognostic (6.90e-2)"	"unprognostic (2.41e-1)"	"unprognostic (2.27e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.57e-2)"	"unprognostic (1.67e-1)"	"unprognostic (2.15e-1)"	13.7	5.6	10.9	5.9	12.5	5.4	9.7	3.0	32.3	12.4	0.0	11.0	2.7	9.8	1.4	4.1	7.5	6.6	12.5	11.8	7.9	7.0	2.5	13.0	3.2	21.9	7.1	1.5	12.7	22.2	3.9	6.5	20.8	8.4	4.0	5.3	9.8	4.8	37.9	5.4	6.5	6.2	1.1	8.2	12.9	24.5	13.0	1.6	11.0	16.9	2.6	8.2	8.2	15.7	0.1	2.5	0.5	6.7	18.7	11.1	3.7	5.6	11.1	0.7	1.9	6.0	5.4	2.6	16.1	14.6	0.4	0.6	3.9	0.7	0.4	6.7	5.5	23.7	8.1	6.7	12.3	3.9	36.5	8.3	0.8	6.2	0.0	0.7	5.3	2.1	18.9	5.5	4.0	1.7	2.3	43.3	2.9	6.7	4.7	15.6	3.7	20.3	0.9	1.4	4.2	1.5	0.4	0.2	6.2	1.0	0.8	7.8	11.2	8.3	10.5	5.7	3.7	10.9	0.9	12.4	3.5	0.3	6.7	4.1	1.7	3.4	0.8	2.5	0.4	0.1	0.3	1.1	2.0	0.0	0.0	0.4	0.1	3.0	2.7	0.1	0.7	1.1	10.9	12.5	3.0	32.3	11.8	7.9	21.9	7.1	20.8	1.1	13.0	15.7	9.4	3.2	11.6	6.2	10.8	10.1	2.6	2.5	1.8	25.6	6.4	4.3	7.7	8.6	5.5	9.2	0.0	0.5	58.9	7.1	0.0	3.1	48.9	2.1	20.7	8.6	0.0	1.7	39.4	12.9	4.8	12.1	7.1	3.6	31.8	0.3	10.4	0.9	10.2	55.5	43.5	5.1	6.1	22.1	190.8	197.0	17.4	53.9	14.2	12.2	15.4	1.2	22.6	12.5	1.5	12.3	3.8	18.0	27.0	3.0	0.1	0.2	6.9	3.6	6.6	9.0	10.2	8.6	8.5	0.5	8.1	0.4	37.0	1.0	6.8	1.3
PDE4B	DPDE4	ENSG00000184588	"Phosphodiesterase 4B"	Q07343	1	65792514-66374579	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Hydrolase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 75.5;brain: 109.1"	"Group enriched"	"Detected in many"	5	"Oligodendrocyte precursor cells: 1722.6;Oligodendrocytes: 4039.6"	"Cancer enhanced"	"Detected in all"		"glioma: 18.9"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 88.9"	"Group enriched"	"Detected in all"	5	"B-cells: 37.4;granulocytes: 88.9;T-cells: 34.7"	"Cell line enhanced"	"Detected in many"		"AN3-CA: 61.8;HUVEC TERT2: 93.2;NTERA-2: 56.1;SK-MEL-30: 58.6;TIME: 52.6;U-266/84: 51.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003005	Uncertain		Approved	"Golgi apparatus,Cytosol"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 70: Brain - Nervous system development"	"Cluster 12: NES - Nervous system development"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	"Golgi apparatus"	Cytosol	"HPA003005: AB_1079587"	"unprognostic (7.86e-2)"	"unprognostic (3.13e-1)"	"unprognostic (4.62e-2)"	"unprognostic (2.90e-1)"	"unprognostic (3.21e-1)"	"unprognostic (3.33e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.15e-3)"	"unprognostic (1.04e-2)"	"unprognostic (6.10e-2)"	"unprognostic (8.78e-2)"	"unprognostic (4.24e-2)"	"prognostic unfavorable (5.04e-4)"	"unprognostic (2.89e-2)"	"unprognostic (3.54e-1)"	"unprognostic (9.04e-3)"	"unprognostic (8.33e-3)"	18.3	3.1	40.1	39.5	82.5	75.5	20.0	63.3	53.5	7.2	1.6	8.3	4.6	8.3	1.1	4.5	4.2	10.1	21.4	45.7	68.4	5.4	10.9	14.7	23.2	85.9	74.4	2.1	1.6	1.4	3.8	17.2	78.5	23.0	10.5	14.1	21.1	12.1	44.3	8.9	12.2	12.4	66.4	22.6	5.1	3.8	62.9	14.0	7.2	15.0	19.9	32.1	4.6	109.1	0.2	18.5	34.7	61.8	1.6	1.7	0.1	11.5	13.3	10.1	13.4	0.0	0.0	5.3	0.2	20.7	0.4	0.1	0.3	0.0	9.7	15.5	0.1	0.3	5.2	0.0	1.2	13.1	0.0	3.4	0.5	4.5	0.2	1.6	93.2	0.0	0.0	3.3	4.7	0.3	0.0	7.5	56.1	0.0	0.7	2.6	6.2	3.6	8.7	0.0	0.2	26.6	0.0	3.0	58.6	2.9	0.2	4.5	52.6	7.2	1.9	4.6	1.9	1.5	51.6	19.3	8.6	13.4	3.7	10.8	6.8	22.0	10.1	5.8	19.5	36.8	19.4	14.8	6.2	37.4	21.3	15.0	88.9	11.3	5.7	6.4	34.7	9.6	40.1	82.5	63.3	53.5	45.7	68.4	85.9	74.4	78.5	66.4	62.9	109.1	24.7	9.6	12.2	531.8	233.3	20.3	28.4	0.5	27.9	40.9	51.6	34.3	25.4	0.0	6.9	5.5	0.0	7.3	79.8	0.4	0.0	0.8	14.4	1.7	14.9	36.8	4.2	0.0	315.6	0.9	2.0	20.2	9.7	4.2	15.2	0.2	11.7	2.4	13.0	114.4	559.7	1.9	8.2	40.6	187.4	9.4	0.3	176.9	51.6	173.3	67.0	19.3	1.0	1722.6	4039.6	0.1	0.4	2.6	351.9	93.6	0.0	2.1	1.5	4.0	0.0	54.0	10.3	0.7	0.8	4.8	8.1	5.6	143.1	0.4	1.3	9.4
PDE4C	DPDE1	ENSG00000105650	"Phosphodiesterase 4C"	Q08493	19	18208652-18248200	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		Hydrolase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"tongue: 21.3"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 255.9;Gastric mucus-secreting cells: 141.2;Paneth cells: 251.4;Proximal enterocytes: 73.0;Skeletal myocytes: 106.5;Undifferentiated cells: 103.3"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in some"	4	"basal ganglia: 1.2;cerebral cortex: 1.1"	"Immune cell enhanced"	"Detected in single"		"basophil: 1.0"	"Lineage enriched"	"Detected in single"	4	"granulocytes: 1.0"	"Cell line enhanced"	"Detected in some"		"BEWO: 2.9;Hep G2: 2.0;U-87 MG: 4.4"									"HPA048975, HPA054218"	Approved		Approved	"Midbody ring,Centrosome,Cytosol"		Yes	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Centrosome, Cytosol"	"Midbody ring"	"HPA048975: AB_2680581, HPA054218: "	"unprognostic (4.20e-2)"	"unprognostic (4.02e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.27e-1)"	"unprognostic (5.22e-4)"	"unprognostic (1.44e-2)"	"unprognostic (7.70e-2)"	"unprognostic (1.15e-1)"	"unprognostic (4.01e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-3)"	"unprognostic (2.21e-1)"	"unprognostic (7.25e-10)"	"unprognostic (2.73e-2)"	"unprognostic (2.65e-1)"	"unprognostic (9.21e-2)"	"unprognostic (2.45e-2)"	1.4	0.6	0.2	0.1	1.2	0.5	0.7	0.0	1.1	3.2	0.0	4.3	0.7	3.4	3.4	0.7	3.0	1.1	4.4	0.2	0.0	4.8	1.3	3.4	0.2	0.0	0.0	1.8	0.7	0.2	2.8	3.7	0.0	2.3	0.6	0.2	0.5	2.7	8.3	0.3	2.4	1.8	0.0	2.1	3.8	2.5	0.0	0.0	1.1	21.3	0.1	1.0	1.7	0.0	0.0	0.1	0.0	0.1	0.0	0.1	2.9	0.0	0.0	0.1	0.1	0.6	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	2.0	0.1	0.0	0.2	0.3	0.0	1.2	0.0	0.2	0.0	0.1	0.4	0.9	0.0	0.1	0.1	0.1	0.0	0.2	0.1	0.1	0.1	0.2	0.0	0.0	0.1	0.4	0.1	0.2	0.0	0.7	0.2	0.2	0.0	0.1	0.0	0.3	0.0	0.6	0.3	0.1	4.4	0.1	0.0	1.0	0.1	0.2	0.1	0.0	0.1	0.1	0.1	0.1	0.0	0.2	0.1	0.1	0.7	0.2	0.1	0.1	0.0	0.0	0.2	1.2	0.0	1.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	3.2	10.6	2.0	0.8	5.5	5.8	8.6	5.2	3.9	0.2	0.4	35.3	4.3	22.4	0.0	6.2	2.1	0.0	255.9	0.0	0.0	32.9	0.1	0.1	4.6	7.2	0.0	8.2	0.0	4.3	6.3	141.2	0.1	4.5	0.0	1.1	0.3	0.5	0.0	2.1	55.2	4.1	1.4	4.5	38.4	0.6	2.1	1.8	0.0	0.4	1.9	1.0	0.5	0.9	0.0	251.4	4.1	1.6	1.8	73.0	0.0	9.4	3.0	46.0	106.5	17.2	1.9	2.2	28.6	3.8	1.1	1.2	0.0	103.3	17.3
PDE4D	DPDE3	ENSG00000113448	"Phosphodiesterase 4D"	Q08499	5	58969038-60522120	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 74.9;skeletal muscle: 70.4"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 619.3;Excitatory neurons: 2969.7;Inhibitory neurons: 1116.9;Oligodendrocyte precursor cells: 848.0;Oligodendrocytes: 443.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in many"	5	"eosinophil: 57.9"	"Lineage enriched"	"Detected in many"	5	"granulocytes: 57.9"	"Cell line enhanced"	"Detected in many"		"A549: 62.2;AN3-CA: 70.4;HeLa: 104.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045895	Uncertain		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 20: HeLa - Mitochondria"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Plasma membrane"	Cytosol	"HPA045895: AB_10960275"	"unprognostic (1.14e-1)"	"unprognostic (8.73e-3)"	"unprognostic (4.35e-2)"	"unprognostic (7.87e-2)"	"unprognostic (5.97e-2)"	"unprognostic (2.03e-1)"	"unprognostic (8.10e-4)"	"unprognostic (1.17e-1)"	"unprognostic (6.59e-2)"	"unprognostic (1.84e-1)"	"unprognostic (2.71e-1)"	"unprognostic (2.65e-1)"	"prognostic favorable (4.00e-5)"	"unprognostic (1.51e-1)"	"unprognostic (8.20e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.56e-2)"	8.9	1.3	3.3	9.8	9.9	74.9	4.6	0.0	11.3	5.3	0.0	21.0	5.5	7.4	18.4	13.7	7.3	9.1	15.7	4.4	4.2	17.2	2.8	13.3	5.3	7.0	2.0	3.0	3.7	5.5	6.7	16.6	1.2	19.9	15.0	21.4	7.4	21.2	70.4	4.5	7.0	15.3	0.8	4.0	10.3	3.4	3.8	8.6	7.4	34.4	5.6	22.0	8.2	5.7	0.1	62.2	12.8	70.4	2.3	4.4	10.1	1.6	1.8	3.4	4.9	24.5	2.0	4.8	0.2	0.5	10.3	10.6	0.0	2.8	5.9	2.9	7.0	9.2	104.6	5.3	9.1	4.4	0.7	9.3	2.3	9.6	1.7	1.1	7.3	0.3	0.0	1.6	5.9	4.5	3.6	10.3	2.4	1.8	3.2	1.2	16.0	10.5	15.9	23.5	2.3	8.0	16.4	27.1	14.2	11.4	1.9	9.3	8.5	0.9	0.2	12.0	3.3	3.5	0.1	0.5	10.3	17.3	2.7	4.2	2.0	57.9	1.5	0.1	1.5	11.0	1.4	0.7	1.4	11.3	0.9	0.7	3.1	0.4	0.2	0.0	0.8	1.1	3.3	9.9	0.0	11.3	4.4	4.2	7.0	2.0	1.2	0.8	3.8	5.7	22.5	32.1	110.0	619.3	32.3	10.6	30.1	6.6	35.3	20.2	5.1	2.7	35.7	8.6	30.2	42.3	73.0	11.3	118.6	28.1	11.7	0.6	21.4	19.0	8.6	16.9	33.4	2.1	2969.7	1.8	25.7	27.5	40.2	21.9	22.2	0.3	17.2	0.8	5.2	1.7	1116.9	18.2	6.1	4.8	11.1	36.6	1.5	29.5	10.6	407.5	6.0	12.0	29.9	848.0	443.3	8.2	11.9	4.9	44.4	43.3	8.9	27.5	19.4	52.8	0.0	64.0	6.3	1.1	7.7	40.6	8.8	3.1	94.3	1.1	11.7	26.5
PDE5A		ENSG00000138735	"Phosphodiesterase 5A"	O76074	4	119494397-119628804	"Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Hydrolase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9"	"Group enriched"	"Detected in all"	4	"prostate cancer: 7.0;thyroid cancer: 27.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6"	"Region enhanced"	"Detected in all"		"cerebellum: 18.2"	"Low region specificity"	"Detected in all"			"HPA004729, HPA012873"	Approved		Approved	Cytosol		NA	NA		850000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 48: Smooth muscle cells - ECM organization"	Cytosol		"HPA004729: AB_1079588, HPA012873: AB_1855124"	"unprognostic (6.95e-2)"	"prognostic favorable (5.20e-4)"	"unprognostic (1.28e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.25e-1)"	"unprognostic (3.66e-2)"	"unprognostic (7.36e-2)"	"unprognostic (2.58e-2)"	"unprognostic (2.29e-2)"	"unprognostic (6.97e-2)"	"unprognostic (2.05e-2)"	"unprognostic (2.54e-1)"	"unprognostic (2.16e-2)"	"unprognostic (1.52e-2)"	"unprognostic (8.98e-2)"	"unprognostic (8.71e-3)"	"prognostic unfavorable (1.17e-4)"	15.4	11.3	0.9	10.9	3.5	2.1	9.6	4.9	3.7	32.7	12.6	37.0	15.5	14.4	41.5	41.3	22.9	10.4	12.8	1.4	3.6	5.9	1.5	22.1	6.4	4.9	8.2	5.4	12.4	8.3	3.5	13.2	5.2	59.8	25.9	9.6	9.8	49.8	6.9	5.0	18.9	11.4	0.0	5.8	9.6	9.4	3.4	3.7	16.8	5.6	3.5	14.6	15.8	1.9	16.7	0.8	11.0	1.2	3.7	5.5	1.9	10.7	47.5	0.5	1.0	1.0	1.3	1.6	0.5	13.4	3.0	5.8	3.5	1.7	1.3	0.4	7.4	18.5	2.6	0.9	65.9	3.9	1.7	6.1	3.3	1.1	0.1	24.6	1.4	3.7	2.0	2.9	1.6	0.9	5.0	0.6	2.3	1.8	2.8	0.7	5.9	4.3	4.1	4.9	4.3	8.8	13.0	15.3	1.3	8.1	2.7	2.1	2.5	6.2	5.2	3.4	1.5	4.1	2.0	1.5	5.9	1.0	0.9	0.0	0.0	0.0	0.1	0.0	0.5	0.4	0.3	0.1	0.0	0.3	0.1	0.2	0.4	0.2	0.1	0.1	0.1	1.2	0.9	3.5	4.9	3.7	1.4	3.6	4.9	8.2	5.2	0.0	3.4	1.9	7.8	6.4	3.9	19.9	1.3	3.4	2.8	1.1	5.7	8.1	11.0	8.4	5.5	14.3	3.7	1.8	14.6	0.4	0.9	15.5	0.0	15.8	30.6	5.0	12.6	7.8	2.4	0.0	66.1	2.9	0.3	28.1	1.1	3.9	1.3	1.6	0.7	0.9	0.3	5.0	58.3	9.5	2.0	0.0	3.5	11.5	20.8	11.3	5.4	40.3	1.3	28.5	2.1	56.8	41.1	3.9	10.3	104.9	1.4	3.6	7.9	0.5	0.8	5.8	19.7	5.5	80.9	5.4	6.3	3.5	2.4	0.3	1.7	7.0	11.1	2.6
PDE6A	"PDEA, RP43"	ENSG00000132915	"Phosphodiesterase 6A"	P16499	5	149857953-149944793	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Sensory transduction, Vision"	Hydrolase	"Disease variant, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	68	"retina: 1119.5"	"Cell type enriched"	"Detected in many"	11	"Rod photoreceptor cells: 2946.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"Immune cell enhanced"	"Detected in single"		"basophil: 1.1"	"Low lineage specificity"	"Detected in single"			"Cell line enriched"	"Detected in single"	5	"CACO-2: 2.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA016970, HPA074677"	Enhanced					NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 79: Retina - Phototransduction"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 46: Photoreceptor cells - Phototransduction"			"HPA016970: AB_1855125, HPA074677: AB_2732264"	"unprognostic (6.85e-2)"	"unprognostic (8.84e-2)"	"unprognostic (1.70e-2)"	"unprognostic (4.11e-2)"	"unprognostic (1.12e-2)"	"unprognostic (5.72e-2)"	"unprognostic (4.39e-3)"	"unprognostic (8.83e-2)"	"unprognostic (6.54e-2)"	"unprognostic (5.91e-3)"	"unprognostic (1.77e-2)"	"unprognostic (9.21e-2)"	"unprognostic (7.57e-5)"	"unprognostic (9.93e-2)"	"unprognostic (3.08e-1)"	"unprognostic (1.31e-1)"	"unprognostic (2.26e-2)"	0.1	0.7	0.5	0.2	0.5	0.9	0.2	1.4	0.7	0.1	0.2	1.2	0.2	0.1	16.3	0.9	0.2	0.2	0.2	0.5	0.5	0.1	0.1	0.3	0.1	0.3	0.3	0.2	0.2	0.2	1.7	0.1	0.5	0.3	0.9	1119.5	0.4	0.2	0.3	0.6	0.1	0.1	0.2	0.2	0.2	1.5	0.6	0.0	0.4	0.0	0.2	0.0	0.1	1.2	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.0	0.0	0.1	0.0	2.5	0.2	0.3	0.4	0.0	0.4	0.2	0.0	0.1	0.1	0.1	0.0	0.2	0.4	0.2	0.0	0.2	0.1	0.0	0.3	0.3	0.2	0.2	0.0	0.0	0.1	0.4	0.4	0.1	0.1	0.2	0.1	0.0	0.1	0.0	0.1	0.1	0.1	0.3	0.2	0.3	0.0	0.2	0.0	0.1	0.3	0.1	0.4	0.2	0.4	0.1	0.1	0.2	0.1	0.1	0.2	0.2	0.1	1.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.3	0.1	0.1	0.6	0.2	0.1	0.2	0.1	0.0	0.5	0.5	1.4	0.7	0.5	0.5	0.3	0.3	0.5	0.2	0.6	1.2	0.9	0.0	5.8	0.0	0.4	1.1	0.6	0.8	0.0	150.5	0.5	0.4	6.7	0.0	2.8	0.0	244.0	1.1	1.6	14.3	0.0	0.1	18.4	1.5	0.5	11.6	0.0	0.0	1.2	0.2	2.2	1.2	0.0	2.5	3.8	1.9	2.2	0.6	0.3	75.7	0.6	0.4	2.0	1.9	0.4	5.5	1.2	1.5	0.0	0.0	1.4	263.1	5.2	0.5	0.2	0.1	2.8	0.4	0.3	0.4	0.4	0.1	3.2	2946.4	0.0	1.0	1.2	2.3	0.8	5.4	0.6	2.9	1.5	2.2	2.7	0.2
PDE6B	"CSNB3, CSNBAD2, PDEB, rd1, RP40"	ENSG00000133256	"Phosphodiesterase 6B"	P35913	4	625573-670782	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Sensory transduction, Vision"	Hydrolase	"Congenital stationary night blindness, Disease variant, Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	10	"retina: 385.0"	"Cell type enriched"	"Detected in many"	5	"Rod photoreceptor cells: 460.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in some"		"EFO-21: 11.5;JURKAT: 17.3;MOLT-4: 31.3;REH: 16.8;SCLC-21H: 20.2;SH-SY5Y: 11.9;U-266/84: 24.0"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA054148, HPA059929"	Enhanced		Approved	Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 77: Retina - Visual perception"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 46: Photoreceptor cells - Phototransduction"	Cytosol		"HPA054148: AB_2682401, HPA059929: AB_2684166"	"unprognostic (2.43e-2)"	"unprognostic (1.33e-4)"	"unprognostic (2.45e-4)"	"unprognostic (7.18e-3)"	"unprognostic (1.88e-2)"	"unprognostic (5.04e-3)"	"unprognostic (7.32e-3)"	"prognostic favorable (5.34e-4)"	"unprognostic (9.70e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.37e-2)"	"unprognostic (2.33e-2)"	"unprognostic (4.09e-2)"	"unprognostic (1.67e-2)"	"unprognostic (2.26e-1)"	"unprognostic (2.41e-3)"	"unprognostic (1.85e-1)"	1.9	2.2	13.5	5.5	25.7	8.4	4.1	8.2	22.3	2.5	1.9	1.7	1.2	2.7	4.0	1.7	10.2	3.7	5.9	11.2	22.6	4.9	1.0	4.6	14.3	22.8	19.9	2.8	1.8	8.2	4.1	3.1	25.5	2.8	1.3	385.0	3.8	3.0	1.1	2.1	3.0	2.5	9.3	10.1	2.9	4.4	24.1	12.2	12.0	0.1	9.3	3.8	1.4	39.3	0.1	0.0	1.2	0.5	0.3	0.4	0.4	0.0	0.1	0.8	2.0	0.0	0.1	0.3	11.5	0.3	0.9	0.1	2.5	0.6	0.0	0.1	0.0	1.0	0.3	0.1	5.8	0.2	0.4	0.7	0.0	3.5	0.0	0.8	1.1	17.3	0.1	1.0	0.1	0.3	31.3	0.1	9.4	0.7	0.0	16.8	0.2	0.2	2.1	1.3	20.2	11.9	0.0	0.3	0.1	4.2	0.6	0.0	0.4	0.2	1.2	0.2	0.4	7.7	24.0	0.3	0.3	0.3	0.2	16.8	5.4	0.9	14.0	7.7	12.6	12.8	9.3	9.8	8.5	21.4	14.6	15.8	1.4	14.4	8.1	18.2	15.5	9.4	13.5	25.7	8.2	22.3	11.2	22.6	22.8	19.9	25.5	9.3	24.1	39.3	0.5	3.2	5.0	4.2	6.4	0.4	2.1	1.2	2.8	20.7	3.9	2.4	4.4	0.0	3.5	0.0	83.4	0.1	8.4	0.2	1.9	6.9	0.4	7.0	2.2	2.9	1.8	7.4	40.3	0.6	0.3	1.3	1.5	2.5	3.8	5.4	2.2	0.0	11.3	11.8	27.3	0.5	4.1	5.1	1.4	0.3	1.5	3.3	3.6	4.7	6.2	31.1	7.2	10.1	33.9	0.8	0.2	1.5	7.5	1.9	0.0	8.4	11.2	460.1	0.0	1.6	1.1	4.3	11.0	1.9	0.3	0.3	5.9	3.5	0.4	1.3
PDE6C	"ACHM5, COD4, PDEA2"	ENSG00000095464	"Phosphodiesterase 6C"	P51160	10	93612537-93666010	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Sensory transduction, Vision"	Hydrolase	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in single"	26	"retina: 23.1"	"Cell type enriched"	"Detected in some"	13	"Cone photoreceptor cells: 56.3"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"									NA	NA				"Cluster 79: Retina - Phototransduction"		"Cluster 9: Photoreceptor cells - Phototransduction"				"unprognostic (1.39e-3)"	"unprognostic (7.41e-3)"	"unprognostic (2.61e-2)"	"unprognostic (2.24e-1)"	"unprognostic (3.17e-2)"	"unprognostic (5.23e-3)"	"unprognostic (2.46e-3)"	"unprognostic (2.81e-3)"	"unprognostic (9.68e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.51e-2)"	"unprognostic (2.96e-3)"	"unprognostic (2.19e-7)"	"unprognostic (1.19e-1)"	"unprognostic (6.61e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.80e-3)"	0.1	0.1	0.2	0.0	0.2	0.2	0.1	0.8	0.3	0.3	0.0	0.1	0.0	0.1	0.0	0.1	0.2	0.0	0.1	0.2	0.2	0.1	0.1	0.1	0.1	0.2	0.0	0.2	0.1	0.0	0.2	0.0	0.2	0.2	0.0	23.1	0.1	0.0	0.5	0.5	0.1	0.0	0.0	0.1	0.1	0.1	0.4	0.0	0.1	0.0	0.0	0.2	0.2	0.5	0.0	0.1	0.0	0.2	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.2	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	0.8	0.3	0.2	0.2	0.2	0.0	0.2	0.0	0.4	0.5	0.0	0.0	0.0	2.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.3	0.0	0.0	0.0	56.3	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.2	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	1.0	0.0	0.7	0.0	0.5	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.2	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.1	0.0	0.0
PDE6D	JBTS22	ENSG00000156973	"Phosphodiesterase 6D"	O43924	2	231732433-231786272	"Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Sensory transduction, Vision"		"Ciliopathy, Joubert syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 211.9;Late spermatids: 147.9;Spermatocytes: 236.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA037433, HPA037434"	Uncertain					NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 66: Spermatocytes - Spermatogenesis"			"HPA037433: AB_2675475, HPA037434: AB_10672490"	"unprognostic (1.95e-1)"	"unprognostic (2.33e-2)"	"unprognostic (1.22e-1)"	"unprognostic (7.72e-3)"	"unprognostic (7.07e-2)"	"unprognostic (5.41e-2)"	"unprognostic (1.15e-1)"	"unprognostic (9.48e-2)"	"unprognostic (3.91e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.69e-1)"	"unprognostic (4.75e-2)"	"prognostic unfavorable (4.02e-5)"	"unprognostic (1.11e-2)"	"unprognostic (1.80e-2)"	"unprognostic (1.46e-1)"	"prognostic favorable (4.97e-4)"	16.8	28.1	43.4	16.2	47.3	14.6	16.3	47.4	50.7	19.2	38.0	19.6	13.4	17.6	14.9	16.3	15.5	14.2	19.3	44.4	45.7	19.5	15.4	15.2	23.3	45.6	46.0	13.4	13.2	23.5	25.0	23.0	45.7	13.7	17.6	69.6	14.2	17.6	13.7	16.4	15.7	22.0	46.5	18.8	16.2	27.8	45.8	32.4	14.0	16.7	24.0	17.9	16.4	49.6	26.3	20.3	37.0	28.2	43.7	36.1	15.7	27.0	44.6	40.8	56.9	8.1	24.5	21.4	22.7	23.2	74.9	20.4	22.3	30.2	52.6	63.5	26.4	31.2	12.4	13.0	20.2	20.6	17.2	25.5	26.4	39.8	30.4	27.5	44.1	68.3	9.1	23.5	27.5	52.0	67.7	64.4	28.6	39.6	28.1	45.7	17.0	32.9	42.8	19.5	36.4	32.6	23.0	19.4	46.3	36.1	17.5	43.0	19.5	26.5	7.3	57.9	21.4	57.9	26.3	52.6	27.4	38.6	42.5	84.4	48.2	68.4	46.3	48.7	36.3	50.4	46.0	47.3	49.3	55.5	31.7	44.3	42.0	34.4	64.9	55.8	84.4	43.1	43.4	47.3	47.4	50.7	44.4	45.7	45.6	46.0	45.7	46.5	45.8	49.6	20.8	0.0	8.7	18.3	19.5	13.8	12.4	23.6	21.1	14.7	13.3	17.7	13.1	12.8	15.8	12.9	16.7	16.4	18.2	10.2	25.4	23.1	211.9	6.8	9.2	19.6	17.4	15.8	13.4	23.9	21.9	14.7	13.3	6.5	14.5	7.3	19.2	5.0	18.9	11.8	18.1	10.0	14.2	14.4	15.1	147.9	13.1	17.5	23.2	16.9	24.6	22.0	17.5	48.7	34.0	26.0	14.9	12.4	17.0	10.5	11.2	18.4	11.8	29.0	19.7	10.7	24.9	236.8	65.1	20.3	14.2	13.5	18.5	11.5	10.5	11.0
PDE6G	"PDEG, RP57"	ENSG00000185527	"Phosphodiesterase 6G"	P18545	17	81650459-81663112	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Sensory transduction, Vision"	Hydrolase	"Retinitis pigmentosa"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	99	"retina: 2050.3"	"Cell type enriched"	"Detected in many"	6	"Rod photoreceptor cells: 4448.6"	"Cancer enhanced"	"Detected in many"		"testis cancer: 10.6"	"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	6	"basophil: 127.0;NK-cell: 220.2"	"Group enriched"	"Detected in all"	6	"granulocytes: 127.0;NK-cells: 220.2"	"Cell line enhanced"	"Detected in some"		"Hep G2: 5.2;NB-4: 5.8;NTERA-2: 8.9;REH: 11.9;SuSa: 6.2"	"Region enhanced"	"Detected in some"		"hippocampal formation: 4.7"	"Not detected"	"Not detected"			HPA045118	Supported		Uncertain	Vesicles		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 79: Retina - Phototransduction"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 46: Photoreceptor cells - Phototransduction"	Vesicles		"HPA045118: AB_2732517"	"unprognostic (6.16e-2)"	"unprognostic (1.95e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.51e-3)"	"unprognostic (1.68e-1)"	"unprognostic (1.46e-2)"	"unprognostic (6.33e-2)"	"unprognostic (3.80e-2)"	"unprognostic (1.10e-2)"	"unprognostic (1.02e-1)"	"unprognostic (4.85e-2)"	"unprognostic (5.01e-2)"	"unprognostic (1.94e-2)"	"unprognostic (5.71e-2)"	"unprognostic (5.44e-2)"	"unprognostic (2.73e-1)"	"unprognostic (1.14e-1)"	1.5	0.3	0.0	4.7	0.1	7.8	0.9	0.2	0.5	1.0	0.2	1.6	0.6	0.2	0.1	0.8	0.7	2.5	0.4	0.1	0.7	2.1	4.2	3.0	20.6	0.1	0.2	0.0	0.0	0.1	0.1	12.0	0.2	0.2	1.0	2050.3	0.5	0.4	1.2	0.3	1.6	0.9	0.1	19.9	1.7	0.8	0.3	8.3	0.4	0.3	7.1	3.0	0.1	0.2	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.5	0.0	0.0	0.3	0.1	0.2	0.0	0.9	0.0	0.0	0.0	0.0	5.2	0.8	0.0	0.2	0.0	0.0	0.0	0.0	0.4	2.8	0.2	0.1	0.2	0.4	0.3	0.0	5.8	8.9	0.0	0.0	11.9	0.0	1.9	0.0	0.0	0.0	0.2	0.0	0.1	0.1	6.2	0.1	0.8	1.2	0.2	0.0	0.0	0.1	0.1	0.6	0.9	0.4	3.1	0.1	127.0	18.1	30.5	4.1	26.2	1.3	2.7	0.8	2.3	28.9	5.1	2.1	7.4	2.4	220.2	15.5	2.9	0.1	13.5	0.0	0.1	0.2	0.5	0.1	0.7	0.1	0.2	0.2	0.1	0.3	0.2	0.3	0.0	0.6	0.3	1.1	0.9	0.0	0.0	0.6	422.5	0.3	0.4	0.2	0.0	0.0	5.5	517.1	0.2	4.3	0.1	1.9	0.4	0.8	1.5	0.3	27.2	0.0	1.7	0.2	0.2	0.4	0.2	0.0	0.5	23.6	0.1	2.9	0.2	22.6	262.5	0.1	0.2	0.0	4.8	8.0	2.3	0.0	4.4	3.6	0.0	13.3	709.0	11.3	0.0	0.1	0.2	0.0	0.0	0.8	0.1	0.1	1.0	0.0	4448.6	0.0	0.1	0.1	1.1	0.2	0.3	1.4	0.3	1.7	2.1	0.0	0.1
PDE6H		ENSG00000139053	"Phosphodiesterase 6H"	Q13956	12	14973042-14981865	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Sensory transduction, Vision"	Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	226	"retina: 911.3"	"Group enriched"	"Detected in some"	6	"Cone photoreceptor cells: 831.9;Rod photoreceptor cells: 218.8"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"AN3-CA: 1.0"	"Low region specificity"	"Detected in single"							HPA045118	Supported		Uncertain	Vesicles		NA	NA				"Cluster 79: Retina - Phototransduction"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 9: Photoreceptor cells - Phototransduction"	Vesicles		"HPA045118: AB_2732517"					"unprognostic (1.47e-3)"										"unprognostic (1.07e-2)"			0.0	0.4	0.3	0.0	0.4	4.0	0.0	0.1	1.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	2.3	0.0	0.0	0.1	0.0	0.3	0.4	0.0	0.0	0.0	0.0	0.9	0.5	0.0	0.0	911.3	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.2	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.4	0.1	1.0	0.3	2.3	0.3	0.4	0.5	0.2	0.3	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	62.9	0.0	0.0	0.1	0.0	0.0	0.0	831.9	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.5	0.0	0.0	0.5	0.0	21.8	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.9	23.5	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.5	0.0	0.0	0.6	81.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	218.8	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0
PDE7A	HCP1	ENSG00000205268	"Phosphodiesterase 7A"	Q13946	8	65714334-65842322	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lymphoid tissue: 108.3"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 102.4;Inhibitory neurons: 111.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"Karpas-707: 94.9;MOLT-4: 167.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018770, HPA027340"	Approved					NA	NA			"Cluster 30: Non-specific - Translation"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"			"CAB018770: AB_677329, HPA027340: AB_1855127"	"unprognostic (2.76e-1)"	"unprognostic (2.94e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.17e-2)"	"unprognostic (2.15e-1)"	"unprognostic (7.11e-2)"	"prognostic unfavorable (5.64e-4)"	"unprognostic (1.44e-2)"	"unprognostic (6.94e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.76e-2)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (1.35e-4)"	"unprognostic (3.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (5.06e-2)"	"unprognostic (2.03e-2)"	8.5	3.1	5.2	28.5	8.0	26.6	19.8	8.5	7.2	13.4	7.7	7.6	11.4	6.3	14.0	6.6	7.9	11.5	49.3	5.1	5.3	18.8	5.5	19.1	58.8	6.6	5.2	6.0	14.3	3.1	13.4	8.3	5.2	13.7	9.8	14.0	20.8	8.6	63.6	8.2	26.4	5.5	3.9	29.4	13.0	10.3	8.2	108.3	22.9	75.9	43.0	9.9	8.9	11.1	12.5	10.8	47.2	22.2	6.7	5.8	20.0	9.3	7.9	11.5	11.0	12.8	8.1	35.0	2.2	5.8	10.2	13.8	17.5	19.7	12.0	41.3	8.9	25.6	18.5	9.6	3.4	20.3	9.8	8.3	32.0	7.4	22.3	9.9	11.4	84.0	19.1	94.9	7.9	6.8	167.6	23.0	50.3	10.1	4.8	61.8	7.2	9.2	7.8	24.6	22.9	26.5	9.8	4.9	4.8	32.2	26.1	52.2	7.4	15.9	19.6	11.3	7.6	45.6	21.3	60.3	16.1	42.1	8.9	2.5	0.7	5.5	3.4	0.6	5.5	6.5	5.2	3.4	1.5	7.5	11.9	9.2	2.5	2.3	0.2	2.1	4.7	1.8	5.2	8.0	8.5	7.2	5.1	5.3	6.6	5.2	5.2	3.9	8.2	11.1	8.6	19.2	22.7	41.4	95.1	18.1	13.6	8.8	7.4	27.3	23.1	21.8	46.6	20.0	17.3	3.7	56.3	14.1	93.4	3.7	0.0	8.2	32.1	11.8	12.6	7.9	9.6	31.6	102.4	5.3	8.4	17.2	8.2	13.5	9.5	14.2	6.8	4.3	10.4	18.5	111.3	6.5	12.2	17.3	34.9	15.0	7.5	26.2	16.0	48.7	19.7	10.1	47.4	89.0	86.2	6.1	5.6	7.5	56.3	19.4	5.9	21.3	20.3	66.1	0.0	18.4	11.1	10.3	10.9	6.0	18.8	8.6	81.3	6.8	6.5	10.8
PDE7B		ENSG00000171408	"Phosphodiesterase 7B"	Q9NP56	6	135851701-136195574	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 22.1"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 346.4;Excitatory neurons: 136.7;Inhibitory neurons: 166.0;Oligodendrocyte precursor cells: 343.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"naive B-cell: 1.3"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in some"		"ASC diff: 8.7;ASC TERT1: 10.2;EFO-21: 16.2;HeLa: 9.6;HSkMC: 22.4;HUVEC TERT2: 10.8;U-2197: 11.4"	"Region enriched"	"Detected in all"	5	"basal ganglia: 125.3"	"Low region specificity"	"Detected in all"			HPA023967	Uncertain		Approved	Nucleoplasm		No	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm		"HPA023967: AB_1855128"	"unprognostic (3.18e-1)"	"unprognostic (3.47e-1)"	"unprognostic (2.34e-1)"	"unprognostic (1.79e-3)"	"unprognostic (3.34e-1)"	"unprognostic (3.22e-4)"	"unprognostic (1.37e-2)"	"unprognostic (3.00e-1)"	"unprognostic (2.80e-1)"	"unprognostic (6.73e-3)"	"unprognostic (1.11e-2)"	"unprognostic (7.85e-2)"	"prognostic favorable (1.59e-4)"	"unprognostic (3.14e-3)"	"unprognostic (2.68e-2)"	"unprognostic (1.43e-1)"	"unprognostic (3.34e-2)"	5.2	2.3	6.5	2.2	22.1	0.1	2.6	3.6	8.1	3.9	2.8	2.5	1.9	7.8	2.2	1.3	2.8	3.4	6.6	2.6	8.7	5.5	3.7	1.7	1.5	6.2	11.6	13.0	0.8	6.2	4.8	1.0	6.0	4.3	2.7	2.4	2.9	10.3	4.7	0.8	2.2	7.6	4.6	1.1	3.6	1.5	15.8	3.8	4.7	8.9	0.8	6.0	3.6	2.8	0.0	5.7	0.2	0.0	8.7	10.2	0.1	0.5	2.9	2.1	1.1	0.0	0.1	0.1	16.2	3.6	0.0	0.0	0.0	0.0	0.7	0.0	0.2	0.0	9.6	0.0	3.7	0.1	0.0	22.4	0.0	4.2	0.0	0.9	10.8	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.8	3.8	0.7	3.9	3.7	0.1	0.2	0.0	0.0	1.8	0.0	2.3	0.0	11.4	0.0	0.1	0.0	0.0	0.6	0.0	0.9	0.0	0.3	0.2	0.0	0.0	0.0	0.4	0.1	0.0	0.8	1.3	0.5	0.3	0.0	0.2	0.0	0.0	0.0	0.1	6.5	22.1	3.6	8.1	2.6	8.7	6.2	11.6	6.0	4.6	15.8	2.8	8.3	0.0	0.5	346.4	11.9	0.4	0.3	0.5	0.0	4.4	0.9	0.4	8.4	2.8	0.2	22.0	0.0	0.1	0.7	0.1	0.0	0.2	0.5	3.1	1.4	23.1	7.3	0.8	136.7	1.6	0.0	9.8	4.6	2.1	10.2	31.1	35.3	3.8	0.3	6.7	166.0	0.0	0.0	1.9	4.8	0.9	12.2	3.2	0.0	70.3	0.7	11.5	0.0	343.8	10.4	0.1	0.0	7.9	0.2	0.4	0.0	1.6	1.6	0.9	13.1	30.6	9.1	0.3	0.1	0.2	1.4	0.0	2.9	4.4	0.0	0.3
PDE8A	HsT19550	ENSG00000073417	"Phosphodiesterase 8A"	O60658	15	84980440-85139145	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	7	"Oligodendrocytes: 968.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"RT4: 89.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007722	Approved		Approved	"Golgi apparatus"		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 45: Intestine - Brush border"	"Cluster 15: RT4 - Unknown function"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	"Golgi apparatus"		"HPA007722: AB_1855130"	"unprognostic (1.68e-1)"	"unprognostic (2.83e-2)"	"unprognostic (4.81e-2)"	"unprognostic (4.97e-2)"	"unprognostic (6.25e-2)"	"unprognostic (3.47e-2)"	"unprognostic (2.97e-2)"	"unprognostic (3.94e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.45e-1)"	"unprognostic (8.99e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.42e-1)"	"unprognostic (3.72e-1)"	"unprognostic (4.26e-1)"	"unprognostic (1.31e-1)"	"unprognostic (1.94e-2)"	16.7	16.6	20.9	8.5	32.3	3.3	10.5	21.9	22.4	11.6	15.2	24.0	15.3	9.1	7.3	6.4	9.0	15.8	8.0	17.3	20.1	24.3	30.0	10.8	5.6	23.8	28.5	12.7	14.5	16.9	6.7	11.4	23.6	6.9	21.9	14.5	6.4	9.6	5.8	6.3	13.6	10.6	19.5	6.3	11.0	11.0	26.9	4.6	12.3	6.5	5.1	17.7	7.0	45.2	29.0	48.4	7.9	5.4	32.7	17.2	9.6	19.4	21.1	16.6	18.9	10.9	16.9	5.8	14.6	25.9	19.7	20.2	33.8	14.9	22.0	10.8	20.2	7.7	30.3	15.6	23.5	4.5	11.3	17.4	9.1	19.6	18.6	14.3	21.6	6.4	15.6	18.3	15.2	24.5	2.6	4.5	3.8	9.5	8.6	3.6	6.5	8.1	13.2	89.0	18.3	14.1	18.9	20.3	55.5	8.7	6.7	8.7	17.1	38.4	13.6	13.9	31.6	8.9	16.7	6.2	26.1	18.1	11.0	0.0	0.9	0.6	0.3	0.7	0.6	0.2	0.5	0.6	0.5	0.3	0.7	0.3	0.0	0.2	1.6	0.0	1.1	0.2	20.9	32.3	21.9	22.4	17.3	20.1	23.8	28.5	23.6	19.5	26.9	45.2	30.7	6.4	26.5	83.9	14.8	11.3	11.1	13.9	18.2	13.0	6.6	5.2	6.8	41.5	15.4	7.3	12.5	8.0	5.5	58.7	7.9	11.3	6.4	12.5	21.6	24.3	14.5	0.8	60.8	9.6	7.1	16.2	26.5	20.6	22.1	17.9	14.3	23.3	10.8	10.1	126.2	19.0	4.1	12.3	18.9	5.6	10.8	19.2	10.6	85.3	9.0	2.6	10.3	119.1	968.6	11.5	31.8	11.3	7.2	25.4	22.1	21.1	10.5	31.2	39.5	17.8	24.5	25.6	17.3	7.5	10.4	4.5	10.8	25.3	28.5	26.4
PDE8B		ENSG00000113231	"Phosphodiesterase 8B"	O95263	5	77210449-77428256	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase	"Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"thyroid gland: 124.7"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 64.9;Excitatory neurons: 183.1;Horizontal cells: 69.0;Inhibitory neurons: 276.5;Muller glia cells: 86.5;Oligodendrocyte precursor cells: 190.5"	"Cancer enriched"	"Detected in many"	6	"thyroid cancer: 35.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+: 13.6;HeLa: 34.8;SK-BR-3: 11.1"									"HPA036911, HPA036912"	Supported		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 20: HeLa - Mitochondria"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Nucleoplasm, Cytosol"		"HPA036911: AB_2675378, HPA036912: AB_10670377"	"unprognostic (1.30e-1)"	"unprognostic (7.95e-2)"	"unprognostic (3.35e-2)"	"unprognostic (7.61e-4)"	"unprognostic (1.59e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.66e-2)"	"unprognostic (4.48e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.26e-2)"	"unprognostic (3.98e-2)"	"unprognostic (2.44e-1)"	"unprognostic (9.04e-3)"	"unprognostic (3.40e-2)"	"unprognostic (3.76e-2)"	"unprognostic (1.98e-1)"	"unprognostic (3.19e-2)"	20.9	4.8	24.2	1.0	28.6	0.4	14.0	4.8	24.6	17.4	0.0	5.6	2.0	26.4	6.3	2.0	28.7	4.3	23.7	25.5	32.5	15.6	2.3	5.2	1.2	20.5	15.9	4.2	7.9	0.8	12.5	23.8	18.8	19.0	1.2	22.5	10.5	11.9	0.7	2.0	3.3	17.7	9.9	0.8	5.5	3.0	36.7	0.3	124.7	0.8	1.0	4.0	4.9	17.2	0.1	4.9	0.8	0.3	1.5	0.0	0.5	1.5	13.6	0.2	0.1	1.4	0.1	0.3	0.1	0.1	0.2	0.6	0.2	0.0	0.2	0.2	0.7	0.4	34.8	0.3	0.0	0.4	0.5	0.8	0.0	0.0	0.0	0.4	0.0	0.5	0.1	0.2	0.0	0.2	0.5	0.8	0.8	0.2	0.1	0.6	0.9	0.4	0.0	0.2	5.4	1.0	2.3	11.1	0.7	0.7	1.8	0.9	0.5	0.3	0.3	0.2	0.5	0.7	0.5	0.4	1.2	0.5	0.3	0.0	0.0	0.1	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	24.2	28.6	4.8	24.6	25.5	32.5	20.5	15.9	18.8	9.9	36.7	17.2	0.8	3.2	2.8	64.9	0.3	0.4	2.0	0.1	0.0	10.8	5.8	3.0	28.0	2.8	1.6	1.8	54.2	0.0	0.2	0.1	0.0	2.3	6.8	15.3	2.1	4.5	4.9	0.0	183.1	0.0	0.1	3.8	0.0	7.9	1.3	1.8	2.9	0.1	0.4	69.0	276.5	1.0	0.0	1.0	1.6	5.1	5.9	0.9	1.8	10.3	0.1	86.5	0.0	190.5	45.5	0.2	0.4	0.0	0.3	29.1	0.2	0.7	0.7	5.8	6.6	1.8	7.7	1.1	2.6	0.5	1.1	0.0	0.1	8.8	1.2	4.2
PDE9A		ENSG00000160191	"Phosphodiesterase 9A"	O76083	21	42653621-42775509	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		Hydrolase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 74.7"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5"	"Cancer enriched"	"Detected in all"	5	"prostate cancer: 31.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 3.1"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA011380, HPA011978"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 38: EFO-21 - Unknown function"	"Cluster 45: Enterocytes - Digestion"	Cytosol	"Nucleoplasm, Plasma membrane"	"HPA011380: AB_1855132, HPA011978: "	"unprognostic (5.75e-2)"	"unprognostic (9.92e-3)"	"unprognostic (3.50e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.40e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.99e-2)"	"unprognostic (6.02e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.25e-2)"	"unprognostic (5.01e-2)"	"unprognostic (1.90e-2)"	"unprognostic (4.01e-3)"	"unprognostic (1.97e-1)"	"unprognostic (6.55e-2)"	"unprognostic (1.79e-1)"	9.4	11.1	12.3	3.9	15.1	0.5	10.8	14.0	12.9	7.2	8.6	74.7	2.9	5.1	19.4	3.7	10.6	6.8	4.3	10.6	12.6	29.8	4.2	4.9	4.8	12.4	14.4	3.5	4.1	6.5	9.9	10.3	12.7	38.5	16.4	10.7	12.7	15.8	2.4	7.0	47.3	8.8	11.0	18.3	13.4	1.9	15.0	7.8	6.5	4.8	3.1	18.9	6.2	12.0	0.0	2.8	29.7	3.7	0.0	0.8	0.5	0.0	0.0	0.0	0.0	3.2	18.2	0.0	30.0	0.0	2.2	0.0	2.7	9.8	0.0	0.0	10.4	0.0	0.0	6.4	2.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	1.7	0.5	0.0	0.0	23.2	1.5	34.7	41.2	14.6	0.0	0.0	0.0	1.2	20.4	7.6	22.5	13.5	5.2	0.0	0.5	7.0	0.2	19.1	0.0	0.0	4.4	0.0	0.0	0.0	0.0	0.0	0.0	12.4	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.9	0.2	0.1	0.2	3.1	0.6	0.4	0.9	0.0	0.4	1.0	0.3	12.3	15.1	14.0	12.9	10.6	12.6	12.4	14.4	12.7	11.0	15.0	12.0	18.6	3.2	5.0	43.4	1.6	1.0	10.9	4.2	6.2	26.4	13.4	12.6	1.6	5.7	2.4	18.4	0.0	0.0	1.0	90.8	29.4	7.3	0.6	18.1	8.5	11.9	13.1	3.2	5.6	2.4	0.1	5.9	1.5	26.8	1.3	6.1	5.7	0.9	7.5	35.3	10.8	25.8	8.2	1.3	0.8	2.2	11.8	1.6	28.4	31.9	1.1	11.0	0.0	29.1	16.6	5.3	105.3	6.0	0.2	28.1	233.5	8.9	1.3	2.8	13.1	0.5	6.4	0.4	2.3	0.5	0.6	0.4	3.8	16.9	24.4	15.0
PFAS	"FGARAT, GATD8, KIAA0361, PURL"	ENSG00000178921	"Phosphoribosylformylglycinamidine synthase"	O15067	17	8247618-8270491	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine biosynthesis"	Ligase		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 49.1"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022140, HPA022886"	Enhanced		Approved	Vesicles		NA	NA		670000	"Cluster 1: Neutrophils - Mixed function"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 52: Non-specific - Transcription"	Vesicles		"HPA022140: AB_1855232, HPA022886: AB_1855233"	"unprognostic (1.90e-1)"	"unprognostic (9.21e-2)"	"unprognostic (2.12e-1)"	"unprognostic (5.19e-3)"	"unprognostic (2.59e-1)"	"unprognostic (6.40e-2)"	"prognostic unfavorable (9.19e-4)"	"unprognostic (3.19e-1)"	"unprognostic (1.42e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.47e-3)"	"unprognostic (1.08e-3)"	"unprognostic (9.51e-3)"	"unprognostic (3.63e-2)"	"unprognostic (6.57e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.85e-1)"	8.4	9.9	4.7	7.8	5.1	9.8	8.2	6.2	5.8	7.8	2.8	6.7	4.8	9.0	2.6	8.4	8.0	2.8	6.3	5.1	3.3	11.0	10.1	5.8	9.8	3.9	3.9	9.7	10.3	5.6	5.5	5.2	4.6	6.9	5.6	5.8	6.4	4.7	6.4	6.8	7.7	6.8	3.3	11.0	7.8	7.8	3.9	7.5	7.8	3.2	8.2	7.6	6.2	6.0	15.6	67.0	33.8	50.2	12.1	10.0	38.7	19.4	7.4	35.1	26.4	32.9	13.7	69.8	30.8	11.4	12.4	35.1	78.5	25.6	25.8	30.6	64.0	40.0	63.2	41.9	10.4	32.9	28.3	9.5	6.2	40.5	25.5	9.9	29.5	36.6	54.8	10.1	13.7	23.0	58.1	28.4	55.7	8.5	29.9	86.0	35.2	32.6	16.1	25.5	20.4	31.7	24.1	15.3	22.2	17.9	15.3	14.9	20.9	19.2	25.0	35.7	49.0	11.8	23.5	33.7	21.0	45.4	32.9	20.2	5.1	12.7	6.8	4.5	8.7	14.8	8.8	7.9	4.4	16.7	10.9	8.6	49.1	5.2	3.7	12.9	5.0	2.3	4.7	5.1	6.2	5.8	5.1	3.3	3.9	3.9	4.6	3.3	3.9	6.0	2.9	0.0	7.9	3.9	6.0	2.4	1.7	1.9	1.8	8.1	4.5	3.7	4.3	1.5	4.1	3.7	6.2	5.2	3.2	2.1	0.0	3.7	2.1	2.4	5.9	3.6	0.0	9.2	5.8	3.0	4.3	4.0	5.6	3.7	1.3	9.7	2.5	4.2	4.6	1.7	5.4	3.5	2.0	2.5	1.4	1.1	5.3	3.4	3.6	4.7	4.5	1.6	4.1	6.6	3.9	1.9	4.9	1.5	5.3	2.9	0.8	2.7	5.1	7.3	0.0	5.1	3.2	5.6	8.8	3.9	2.0	3.1	3.3	7.7	6.2	1.4
PKLR		ENSG00000143627	"Pyruvate kinase L/R"	P30613	1	155289293-155301438	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	Glycolysis	"Allosteric enzyme, Kinase, Transferase"	"Disease variant, Hereditary hemolytic anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 19.6;kidney: 25.1;liver: 92.5"	"Cell type enhanced"	"Detected in some"		"Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9"	"Cancer enriched"	"Detected in some"	9	"liver cancer: 56.0"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	10	"K-562: 107.8"	"Region enhanced"	"Detected in single"		"basal ganglia: 1.6"	"Not detected"	"Not detected"			"HPA006653, CAB034376, CAB034378"	Enhanced		Approved	Cytosol		No	NA		5200000		"Cluster 85: Liver - Metabolism"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Cytosol		"CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632"	"unprognostic (9.16e-2)"	"unprognostic (1.22e-1)"	"unprognostic (2.22e-1)"	"unprognostic (5.98e-2)"	"unprognostic (2.62e-1)"	"unprognostic (7.86e-4)"	"unprognostic (1.53e-2)"	"unprognostic (1.08e-1)"	"unprognostic (8.79e-2)"	"unprognostic (1.89e-1)"	"unprognostic (4.07e-1)"	"unprognostic (4.53e-2)"	"unprognostic (1.96e-2)"	"unprognostic (1.40e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.32e-1)"	"unprognostic (6.21e-3)"	0.0	0.0	0.0	0.0	0.1	19.6	0.0	0.7	0.1	0.0	0.0	0.4	11.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	25.1	92.5	0.0	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.2	0.0	0.0	0.0	0.0	1.2	7.2	0.0	0.0	0.1	0.0	1.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.7	0.0	11.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	107.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.7	0.1	0.0	0.5	0.2	0.2	0.3	0.0	0.4	0.0	0.1	0.0	0.0	0.7	0.7	0.0	0.0	0.0	0.0	0.0	0.1	0.5	0.4	1.5	0.0	1.8	0.0	0.0	0.0	0.6	0.0	0.0	9.3	0.2	0.3	0.1	0.0	22.1	1.2	0.0	0.1	0.1	0.0	0.3	0.0	0.0	0.7	16.3	0.2	0.0	1.2	0.9	0.0	0.0	0.0	23.0	0.0	0.3	0.0	1.0	0.1	0.0	0.0	0.0	0.5	0.0	0.2	0.0	0.0	0.0	14.8	48.9	0.0	0.0	0.0	0.0	0.1	0.3	0.1	0.0	0.0	0.0	0.1	0.0	0.6	0.0
PKM	"OIP3, PK3, PKM2, THBP1"	ENSG00000067225	"Pyruvate kinase M1/2"	P14618	15	72199029-72231822	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Glycolysis, Translation regulation"	"Allosteric enzyme, Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 4207.6;tongue: 2900.8"	"Cell type enhanced"	"Detected in all"		"Basal respiratory cells: 2065.2;Late spermatids: 1763.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB019421, HPA029501"	Uncertain		Enhanced	Cytosol		No	No		310000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Cytosol		"CAB019421: AB_2252325, HPA029501: AB_10602118"	"unprognostic (8.73e-3)"	"unprognostic (4.63e-3)"	"unprognostic (1.68e-2)"	"unprognostic (3.09e-1)"	"unprognostic (6.51e-2)"	"prognostic unfavorable (1.30e-4)"	"prognostic unfavorable (2.74e-6)"	"prognostic unfavorable (2.85e-4)"	"unprognostic (9.51e-2)"	"unprognostic (1.17e-2)"	"prognostic unfavorable (5.17e-5)"	"unprognostic (3.16e-1)"	"unprognostic (3.22e-1)"	"unprognostic (7.85e-2)"	"unprognostic (3.17e-2)"	"unprognostic (1.44e-1)"	"unprognostic (1.25e-2)"	190.5	600.9	539.0	341.4	552.3	439.0	190.5	586.8	629.9	406.8	755.0	225.0	170.8	202.8	205.7	658.3	240.0	212.0	779.6	549.1	561.6	549.5	32.2	236.9	284.1	640.0	559.1	169.4	112.6	269.6	224.1	168.6	636.2	252.6	206.2	1266.7	389.8	291.6	4207.6	350.5	218.0	298.9	522.3	239.2	228.6	235.1	677.1	203.5	174.6	2900.8	429.2	578.5	374.9	530.6	1584.6	3937.1	788.9	938.8	914.3	1009.4	638.7	1684.6	3878.2	2619.1	2623.6	1094.4	1931.2	1184.5	1627.3	3157.6	1937.8	2253.9	2480.9	3383.2	2051.7	2134.0	1126.5	727.7	1809.1	929.7	637.1	955.2	1525.1	926.4	1559.2	2025.1	810.9	3403.0	1558.6	587.3	182.8	933.3	4267.0	965.1	359.4	419.6	966.2	2438.6	1433.3	1046.5	2560.0	2301.7	3557.2	1973.8	804.4	871.5	2226.3	1344.7	1755.4	1291.4	932.0	675.7	1247.3	3003.7	1622.0	2928.7	3110.3	1170.0	1762.1	1037.2	3720.5	1534.4	3002.3	131.9	836.3	138.6	192.6	466.7	187.9	205.2	254.1	190.4	685.6	142.9	215.8	162.5	100.7	108.4	380.1	140.5	334.0	1261.7	539.0	552.3	586.8	629.9	549.1	561.6	640.0	559.1	636.2	522.3	677.1	530.6	95.9	118.6	88.1	107.7	169.6	565.5	708.9	2065.2	307.9	480.7	157.8	174.7	313.2	87.2	759.4	829.4	369.1	566.1	100.2	358.9	802.2	1395.6	315.0	169.2	77.3	207.7	282.2	44.8	90.2	597.0	1416.7	220.1	138.1	188.0	206.7	144.0	73.2	4.3	750.0	1065.0	97.6	166.8	925.7	297.7	532.9	1763.1	157.2	558.8	355.8	38.4	1255.0	784.1	78.2	53.3	33.4	1213.2	264.5	268.1	209.9	431.4	389.1	208.7	396.9	708.6	124.9	160.9	398.2	43.4	98.6	341.6	389.0	575.7	192.7	157.4	380.7	860.7
PNP	"NP, PUNP"	ENSG00000198805	"Purine nucleoside phosphorylase"	P00491	14	20468954-20477089	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Purine salvage"	"Glycosyltransferase, Transferase"	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 333.9;epididymis: 594.8"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 360.6;Erythroid cells: 227.3;Syncytiotrophoblasts: 646.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HL-60: 531.3;U-937: 593.0"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA001625	Enhanced		Supported	Cytosol		NA	NA		58000000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 68: Epididymis - Unknown function"	"Cluster 32: U-937 - Innate immune response"	"Cluster 47: Cytotrophoblasts - Unknown function"	Cytosol		"HPA001625: AB_1854577"	"unprognostic (1.20e-3)"	"unprognostic (2.68e-2)"	"unprognostic (1.04e-2)"	"unprognostic (1.70e-1)"	"unprognostic (3.10e-1)"	"unprognostic (7.06e-2)"	"prognostic unfavorable (4.43e-4)"	"unprognostic (4.94e-3)"	"unprognostic (3.87e-2)"	"unprognostic (7.45e-2)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-1)"	"prognostic favorable (2.24e-4)"	"unprognostic (1.69e-1)"	"unprognostic (7.54e-2)"	"unprognostic (2.46e-1)"	"unprognostic (1.64e-3)"	78.6	24.8	16.1	46.8	16.6	333.9	34.6	22.6	22.7	25.3	18.9	52.2	120.3	14.2	594.8	87.4	18.2	56.8	29.0	17.7	19.6	206.8	98.0	48.6	46.7	20.3	18.1	5.0	23.2	32.0	19.8	132.6	20.1	15.0	61.8	27.1	22.6	27.4	7.3	29.6	60.3	38.7	23.1	44.5	50.6	7.4	21.1	33.5	17.8	10.0	64.4	100.4	41.5	20.1	86.1	113.4	24.0	53.9	26.0	21.0	71.8	85.2	40.3	68.2	67.0	66.1	76.5	227.1	96.8	45.5	81.5	89.9	125.2	159.8	89.5	75.0	109.6	189.1	89.9	109.3	24.2	531.3	94.7	14.4	57.4	206.0	91.0	37.8	295.9	141.0	95.4	137.4	86.7	79.1	157.6	311.3	67.5	215.7	186.1	130.2	35.9	88.3	243.7	79.6	101.9	22.6	163.4	205.0	13.2	32.6	75.5	92.5	240.0	46.1	62.6	105.1	148.4	63.1	113.3	258.9	39.3	593.0	4.6	12.0	30.6	10.3	39.8	27.3	73.6	25.7	44.2	45.0	48.1	28.8	27.6	35.9	3.7	38.5	26.6	27.3	16.7	31.1	16.1	16.6	22.6	22.7	17.7	19.6	20.3	18.1	20.1	23.1	21.1	20.1	149.6	0.0	23.5	5.9	50.3	84.6	67.4	12.6	112.7	4.7	56.3	62.6	3.5	27.1	13.4	82.8	14.6	360.6	45.2	61.1	39.2	43.2	1.3	36.0	12.7	139.4	46.4	227.3	0.6	51.5	41.8	32.4	106.5	65.3	57.7	5.0	24.3	30.6	70.9	16.8	1.1	51.3	18.3	18.1	58.4	0.8	0.3	83.3	30.2	3.7	13.2	78.8	29.9	3.0	0.9	130.8	83.9	0.7	88.6	27.5	41.2	118.9	10.5	18.1	0.0	23.9	41.3	0.4	0.7	114.7	63.9	646.2	62.3	3.1	51.4	77.1
PPAT	"GPAT, PRAT"	ENSG00000128059	"Phosphoribosyl pyrophosphate amidotransferase"	Q06203	4	56393362-56435615	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Purine biosynthesis"	"Allosteric enzyme, Glycosyltransferase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Granulosa cells: 66.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA036091, HPA036092"	Approved		Approved	"Midbody ring"		Yes	No		11000	"Cluster 27: Non-specific - Gene expression"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 40: Granulosa cells - Unknown function"	"Midbody ring"		"HPA036091: AB_2674936, HPA036092: AB_10603132"	"unprognostic (5.11e-2)"	"unprognostic (5.13e-2)"	"unprognostic (1.39e-2)"	"prognostic unfavorable (5.15e-5)"	"unprognostic (1.38e-1)"	"unprognostic (4.37e-3)"	"prognostic unfavorable (1.14e-8)"	"unprognostic (6.74e-3)"	"unprognostic (2.95e-2)"	"unprognostic (3.79e-2)"	"unprognostic (2.88e-3)"	"unprognostic (1.51e-1)"	"prognostic unfavorable (8.34e-4)"	"unprognostic (1.41e-1)"	"unprognostic (3.01e-1)"	"prognostic unfavorable (1.95e-4)"	"unprognostic (1.09e-1)"	2.8	6.1	3.8	5.4	4.0	5.6	7.1	3.7	4.7	4.3	3.6	3.9	4.0	4.6	3.4	4.5	4.4	3.0	2.3	4.1	4.0	6.0	6.1	2.2	8.4	3.4	4.0	7.4	5.9	3.9	2.5	6.7	4.3	3.9	4.8	4.4	5.6	3.1	2.9	4.3	3.2	3.6	3.7	4.3	3.5	8.6	4.1	8.3	5.9	2.9	8.0	6.7	2.6	4.2	23.1	19.0	38.0	18.7	12.2	15.7	31.0	25.2	11.1	20.4	21.6	38.1	27.5	80.6	33.4	11.9	19.0	16.8	74.0	25.4	40.7	21.1	32.8	32.6	22.6	42.2	18.4	65.0	19.5	13.6	19.4	29.0	32.4	12.6	21.8	32.5	83.5	43.3	23.2	20.9	80.6	49.1	50.6	52.0	22.4	67.2	24.9	56.9	34.2	16.2	64.0	31.2	20.1	36.3	23.0	35.4	24.5	13.8	15.3	21.2	36.6	21.4	45.0	32.2	34.5	82.9	23.6	40.7	20.1	4.7	1.8	0.9	3.8	2.7	5.9	7.4	5.1	5.2	2.5	6.1	7.7	7.1	0.5	10.2	3.9	3.2	4.3	3.5	3.8	4.0	3.7	4.7	4.1	4.0	3.4	4.0	4.3	3.7	4.1	4.2	4.8	0.0	5.5	16.6	10.7	31.0	16.0	5.6	28.5	8.4	10.1	9.7	3.8	4.3	8.0	3.7	2.1	29.7	10.3	1.5	9.8	3.7	2.6	5.5	14.1	7.8	4.2	14.9	22.9	2.7	25.2	9.4	4.1	6.9	7.0	66.2	5.3	7.1	7.9	38.7	15.8	4.3	4.1	1.6	6.0	2.6	7.8	5.2	8.8	5.6	3.1	6.4	2.1	5.5	9.1	3.3	2.7	5.7	15.3	15.0	0.8	12.7	6.2	4.7	0.0	9.3	10.8	16.4	27.5	18.3	31.8	7.7	10.7	21.9	9.0	8.7
PRDX6	"1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX"	ENSG00000117592	"Peroxiredoxin 6"	P30041	1	173477330-173488815	"Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Lipid degradation, Lipid metabolism"	"Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 1315.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006983, CAB008663"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA		120000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane, Cytosol"		"CAB008663: AB_1620994, HPA006983: AB_1079595"	"unprognostic (9.92e-2)"	"unprognostic (1.50e-1)"	"unprognostic (3.67e-1)"	"unprognostic (2.99e-3)"	"unprognostic (1.96e-1)"	"prognostic unfavorable (1.23e-5)"	"unprognostic (5.71e-3)"	"unprognostic (2.80e-2)"	"unprognostic (5.27e-3)"	"unprognostic (3.96e-3)"	"unprognostic (3.19e-3)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (9.51e-4)"	"unprognostic (2.50e-1)"	"unprognostic (7.12e-2)"	"unprognostic (1.15e-1)"	"unprognostic (4.73e-3)"	340.7	157.5	169.5	68.3	181.3	100.1	211.2	197.6	210.1	112.3	164.8	189.1	46.4	108.8	206.3	127.9	149.8	71.9	261.8	184.1	196.6	184.4	482.5	116.7	72.2	181.0	198.3	115.5	114.4	217.5	67.4	70.7	187.5	152.1	221.6	53.9	85.6	99.0	563.5	106.6	59.8	160.2	175.8	70.7	135.2	119.1	176.7	70.7	106.0	382.4	79.0	99.5	109.8	185.5	420.3	127.7	204.7	230.9	778.5	372.7	169.5	843.9	284.3	342.7	241.8	243.9	276.4	272.4	256.4	694.2	120.4	239.8	272.0	259.9	279.0	234.0	243.6	179.5	200.0	277.7	425.7	191.3	56.1	301.0	262.6	181.3	256.6	210.8	339.5	106.7	405.4	52.8	392.9	86.3	131.7	249.1	456.2	219.8	760.5	154.5	236.6	277.0	518.1	95.4	94.9	173.4	285.0	334.0	199.2	296.3	283.8	262.9	228.2	132.5	149.9	201.8	229.5	76.4	123.2	220.7	159.4	162.3	124.3	36.2	42.5	24.8	29.8	39.8	32.8	32.6	29.8	38.4	53.5	24.4	39.8	47.9	25.2	25.7	36.5	79.7	36.1	58.1	169.5	181.3	197.6	210.1	184.1	196.6	181.0	198.3	187.5	175.8	176.7	185.5	278.1	176.3	170.8	127.3	127.4	235.4	404.1	382.8	209.5	31.9	186.1	250.7	528.6	301.7	228.6	277.7	29.2	714.3	158.6	1315.9	860.8	178.6	237.5	206.9	226.8	191.8	142.1	449.5	13.8	202.3	939.1	307.0	111.6	200.0	348.6	216.6	214.2	1120.2	345.0	45.4	13.2	257.4	205.4	164.3	161.0	667.5	340.5	227.1	183.2	17.8	212.9	462.5	83.4	12.5	15.4	147.2	663.4	416.8	176.4	427.1	264.4	827.3	209.1	52.0	184.1	185.7	253.8	123.5	76.8	305.9	264.1	963.5	157.7	512.5	303.6	308.9
PXDN	"D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN"	ENSG00000130508	Peroxidasin	Q92626	2	1631887-1744852	"Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins"	"Hydrogen peroxide"	"Oxidoreductase, Peroxidase"	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"EFO-21: 323.8"	"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			HPA012375	Approved				"Secreted to extracellular matrix"	NA	NA		9100000	"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"			"HPA012375: AB_1855965"	"unprognostic (4.37e-2)"	"prognostic unfavorable (6.28e-4)"	"unprognostic (2.08e-1)"	"prognostic unfavorable (2.75e-4)"	"unprognostic (8.16e-3)"	"unprognostic (1.91e-1)"	"unprognostic (1.92e-2)"	"unprognostic (3.15e-3)"	"unprognostic (6.50e-3)"	"unprognostic (1.34e-2)"	"unprognostic (6.78e-2)"	"unprognostic (2.23e-1)"	"unprognostic (6.13e-3)"	"prognostic unfavorable (6.73e-4)"	"unprognostic (1.18e-1)"	"unprognostic (7.33e-3)"	"unprognostic (5.54e-3)"	59.5	5.5	4.1	24.3	3.5	0.9	33.7	1.9	4.1	18.2	27.5	36.1	7.9	32.8	4.0	4.9	18.0	22.7	22.7	3.1	7.7	9.0	12.4	27.6	5.0	4.2	6.2	32.7	3.8	3.0	11.7	33.4	4.7	17.5	8.7	5.2	13.6	11.1	7.7	6.9	16.3	61.8	2.6	10.0	13.2	6.4	5.2	2.1	8.4	11.5	2.1	33.8	13.5	3.4	39.9	13.9	72.0	0.1	198.3	180.9	54.6	231.4	182.3	99.0	107.9	0.1	0.5	0.0	323.8	230.3	4.5	8.3	0.3	142.3	125.5	0.6	2.4	0.0	139.3	0.0	196.4	0.6	0.0	200.7	41.0	112.2	83.8	299.5	247.0	35.9	0.1	0.0	142.6	23.6	6.8	8.0	58.3	0.0	52.3	13.2	250.8	0.6	115.9	0.1	0.2	131.9	0.2	73.6	0.4	142.9	27.0	0.9	242.4	162.8	79.7	6.2	180.7	0.2	205.4	1.0	0.8	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.3	0.0	0.0	4.1	3.5	1.9	4.1	3.1	7.7	4.2	6.2	4.7	2.6	5.2	3.4	79.1	6.4	2.3	2.6	0.4	2.9	2.8	12.8	0.6	2.5	17.5	14.1	5.8	17.2	7.0	1.8	0.0	0.6	0.2	0.3	0.0	10.4	33.4	4.2	99.4	95.1	1.8	0.0	6.6	0.0	11.3	45.2	0.0	3.4	1.3	43.7	71.4	1.8	1.9	0.0	7.3	1.3	20.3	5.7	4.4	40.7	26.8	0.7	7.2	8.4	0.6	10.0	1.0	55.8	0.7	0.5	0.1	15.1	0.0	14.0	0.0	0.2	6.7	0.8	46.0	120.1	51.1	22.0	16.0	0.5	2.8	1.4	1.0	33.3	0.5	1.4
PXDNL	"FLJ25471, PMR1"	ENSG00000147485	"Peroxidasin like"	A1KZ92	8	51319577-51809445	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Hydrogen peroxide"	"Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"heart muscle: 45.3"	"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 42.2;Early spermatids: 43.8;Excitatory neurons: 25.2;Inhibitory neurons: 68.8;Microglial cells: 16.9;Muller glia cells: 18.6;Spermatocytes: 24.2"	"Group enriched"	"Detected in some"	4	"breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	7	"AF22: 7.7;Daudi: 5.9;SH-SY5Y: 6.1"									HPA007919			Approved	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA				"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Nucleoplasm, Cytosol"		"HPA007919: AB_1855966"	"prognostic unfavorable (3.27e-5)"	"unprognostic (4.59e-4)"	"unprognostic (5.57e-3)"	"unprognostic (2.83e-3)"	"unprognostic (2.71e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.18e-1)"	"unprognostic (7.18e-3)"	"unprognostic (1.85e-1)"	"unprognostic (1.15e-1)"	"unprognostic (7.07e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.60e-4)"	"unprognostic (2.28e-2)"	"unprognostic (3.35e-2)"	"unprognostic (2.42e-2)"	"unprognostic (2.97e-4)"	1.6	0.1	0.2	0.2	0.1	0.0	0.2	0.2	0.6	0.1	0.0	0.1	0.0	0.1	9.4	0.2	0.0	0.1	45.3	0.2	0.3	1.6	0.0	0.2	0.3	0.5	0.6	0.1	0.0	0.2	0.0	0.0	0.8	0.2	0.1	2.9	0.3	0.0	1.4	0.2	0.2	0.0	0.1	0.4	0.0	5.0	0.2	0.5	0.3	2.1	0.5	0.0	0.0	0.4	0.5	0.0	7.7	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.1	5.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	6.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.2	0.6	0.2	0.3	0.5	0.6	0.8	0.1	0.2	0.4	0.3	0.0	0.0	10.7	0.0	0.1	0.1	0.0	0.0	1.2	3.7	0.1	42.2	0.0	0.0	0.0	0.0	0.0	1.5	0.0	1.9	0.0	43.8	0.0	0.0	0.3	0.0	0.0	25.2	0.0	0.0	5.3	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	68.8	0.0	0.0	0.0	0.0	6.3	0.0	0.1	0.0	16.9	0.0	18.6	0.0	14.1	14.9	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.6	0.0	0.2	0.8	24.2	1.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0
RBAK	ZNF769	ENSG00000146587	"RB associated KRAB zinc finger"	Q9NYW8	7	5045821-5069487	"Metabolic proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Repressor"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA071231			Supported	Nucleoplasm		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm		"HPA071231: AB_2686370"	"unprognostic (2.82e-2)"	"unprognostic (1.98e-2)"	"unprognostic (7.40e-2)"	"unprognostic (1.85e-2)"	"unprognostic (5.04e-1)"	"unprognostic (4.32e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.32e-1)"	"unprognostic (4.67e-2)"	"unprognostic (5.91e-2)"	"unprognostic (6.84e-2)"	"unprognostic (5.10e-2)"	"unprognostic (1.28e-1)"	"unprognostic (2.50e-1)"	"unprognostic (3.66e-2)"	"unprognostic (6.12e-3)"	"unprognostic (5.75e-2)"	4.3	3.8	4.1	4.4	4.0	3.7	5.8	6.7	5.4	4.7	3.7	4.6	4.5	5.2	4.7	5.8	4.4	3.7	4.3	3.8	4.5	4.4	6.5	4.0	6.4	4.5	5.0	4.8	5.5	6.9	3.9	4.5	4.4	4.7	4.9	8.4	4.6	4.7	4.2	6.0	5.1	4.4	4.2	5.1	5.0	2.9	4.8	5.6	5.5	6.1	6.7	4.1	4.6	4.8	8.9	6.7	9.2	17.0	6.6	6.1	7.5	5.5	4.3	5.3	6.3	8.3	5.4	10.5	4.5	6.4	10.0	10.8	10.4	8.5	8.2	2.3	7.4	7.7	9.2	6.9	7.0	12.9	8.9	5.9	9.9	5.3	11.8	7.7	5.3	6.1	16.2	3.7	6.7	15.7	3.2	11.9	14.5	3.0	7.0	5.3	14.9	7.7	6.1	11.3	9.4	15.4	7.7	12.6	11.5	11.7	7.7	15.3	4.5	6.3	10.0	7.3	9.1	11.4	9.7	9.2	6.3	9.5	8.2	0.0	0.2	0.4	0.5	0.4	0.7	0.3	0.4	0.3	0.3	0.3	0.5	0.4	0.0	0.5	0.1	0.4	0.3	0.1	4.1	4.0	6.7	5.4	3.8	4.5	4.5	5.0	4.4	4.2	4.8	4.8	7.4	0.0	8.2	0.0	6.5	4.2	3.4	4.7	5.2	8.2	6.1	3.9	13.4	7.2	7.3	0.0	10.4	2.8	7.9	5.1	1.9	5.9	1.1	7.5	10.1	6.1	4.9	11.6	0.0	5.8	2.2	6.7	8.6	6.9	5.7	11.7	7.9	5.3	3.7	21.9	0.0	5.6	2.0	8.2	4.0	1.4	8.1	5.2	3.6	0.0	5.7	6.0	5.2	0.0	0.0	6.0	3.8	8.6	6.7	5.9	5.6	3.7	8.8	8.2	0.0	8.8	7.0	5.0	3.2	7.5	7.0	1.9	6.4	9.1	6.1	4.2
RRM1		ENSG00000167325	"Ribonucleotide reductase catalytic subunit M1"	P23921	11	4094707-4138932	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA replication"	"Allosteric enzyme, Oxidoreductase"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Spermatocytes: 102.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB022093, HPA057265, HPA064297"	Enhanced		Supported	Cytosol		NA	Yes		140000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236"	"unprognostic (4.47e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.99e-3)"	"unprognostic (3.65e-1)"	"unprognostic (2.83e-1)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (1.53e-4)"	"unprognostic (1.31e-2)"	"unprognostic (3.43e-2)"	"unprognostic (6.90e-2)"	"unprognostic (1.06e-3)"	"unprognostic (4.21e-2)"	"unprognostic (6.88e-3)"	"unprognostic (9.20e-3)"	"unprognostic (6.16e-2)"	"unprognostic (8.41e-2)"	"unprognostic (9.93e-3)"	16.6	21.2	5.1	24.8	5.3	32.8	22.7	7.1	6.1	16.9	4.7	25.7	19.3	16.2	10.1	26.5	15.5	11.8	16.4	5.1	5.7	13.4	18.4	12.8	34.4	6.1	5.5	16.4	14.6	24.7	7.1	20.4	6.6	18.5	29.4	23.6	14.7	16.0	30.3	36.1	20.2	20.1	6.2	13.0	17.6	17.9	5.1	56.7	15.6	30.0	45.2	15.6	18.9	6.2	221.6	117.8	188.4	110.0	28.4	56.2	73.0	198.0	98.2	220.7	225.9	106.8	163.8	237.4	47.0	100.1	95.9	173.0	176.9	143.2	259.3	117.3	187.9	121.0	159.8	83.1	11.2	208.9	84.6	26.6	37.8	121.7	86.4	48.3	107.8	140.1	161.1	107.3	186.8	99.6	246.7	41.9	118.2	152.2	119.2	196.1	147.0	84.3	59.4	61.8	159.8	88.1	175.1	104.8	30.0	75.8	102.8	71.4	62.3	203.4	106.0	206.9	147.4	70.3	103.5	252.5	114.1	137.6	130.3	8.3	4.0	4.5	11.3	11.2	21.1	9.2	22.3	16.6	7.3	5.2	17.2	15.0	0.0	10.5	15.6	4.4	41.7	10.3	5.1	5.3	7.1	6.1	5.1	5.7	6.1	5.5	6.6	6.2	5.1	6.2	12.4	19.2	14.4	4.9	17.0	33.4	26.8	31.0	17.6	15.6	15.1	14.4	33.5	14.3	24.7	18.4	6.2	62.8	14.9	13.3	7.9	25.6	69.9	11.5	14.5	15.7	18.0	81.2	11.2	22.2	62.5	22.0	20.4	13.9	7.0	27.3	10.8	15.0	28.3	18.5	12.0	25.0	16.2	11.7	10.3	83.9	13.1	13.9	10.6	6.5	10.7	24.0	5.2	12.1	11.9	15.8	10.4	16.6	31.3	10.1	12.5	8.4	15.5	22.7	13.1	19.5	27.1	102.8	63.1	36.5	29.0	39.7	23.2	18.1	34.3	20.6
RRM2	"C2orf48, FLJ25102"	ENSG00000171848	"Ribonucleotide reductase regulatory subunit M2"	P31350	2	10120698-10211725	"Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins"	"DNA replication"	Oxidoreductase	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	6	"bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1"	"Group enriched"	"Detected in many"	4	"Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA056994	Enhanced		Supported	Cytosol		Yes	Yes		13000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"HPA056994: AB_2683304"	"unprognostic (2.10e-2)"	"unprognostic (1.62e-1)"	"unprognostic (6.40e-3)"	"unprognostic (4.42e-3)"	"unprognostic (5.70e-2)"	"unprognostic (1.69e-1)"	"prognostic unfavorable (1.39e-5)"	"unprognostic (1.04e-3)"	"unprognostic (6.67e-3)"	"unprognostic (4.53e-2)"	"prognostic unfavorable (1.62e-4)"	"unprognostic (5.11e-3)"	"prognostic unfavorable (0.00e+0)"	"unprognostic (3.05e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.38e-1)"	"unprognostic (2.09e-2)"	1.5	1.3	0.3	12.4	0.3	44.2	2.9	0.5	0.4	3.0	1.9	14.2	9.4	2.2	0.7	18.4	0.8	1.1	0.5	0.3	0.3	0.9	3.2	2.4	35.5	0.4	0.4	0.3	1.1	0.3	0.2	4.6	0.4	0.9	19.7	0.2	2.1	0.5	0.1	3.7	7.5	6.1	0.3	11.1	6.0	2.9	0.8	58.1	0.9	0.1	37.6	6.0	4.6	0.5	110.2	25.0	127.1	49.9	7.4	22.5	116.8	209.2	128.6	170.2	187.9	70.8	59.1	114.4	9.5	88.6	151.1	55.0	188.0	136.6	198.0	210.7	41.8	146.3	52.1	105.1	0.8	146.7	87.4	8.1	3.4	234.6	16.2	27.7	103.3	110.4	63.4	328.6	214.3	57.1	167.3	90.9	83.0	133.3	103.6	87.6	187.0	67.8	87.1	62.7	67.7	56.2	198.0	116.6	17.3	51.8	69.2	31.4	57.6	93.1	125.1	66.9	289.6	212.1	184.9	195.9	51.0	134.4	107.7	0.3	0.1	0.1	1.2	0.0	0.0	0.1	0.3	0.8	0.1	0.1	0.1	0.4	0.4	0.8	0.0	0.1	0.2	0.2	0.3	0.3	0.5	0.4	0.3	0.3	0.4	0.4	0.4	0.3	0.8	0.5	0.2	3.2	1.5	0.0	25.0	10.5	3.0	9.2	1.2	0.0	3.9	4.4	1.4	1.5	2.3	0.0	0.0	42.3	5.6	12.9	1.9	1.2	3.9	2.2	3.5	4.2	0.0	214.0	0.1	0.0	254.1	11.2	11.7	3.6	5.7	12.2	3.9	3.7	47.9	0.0	0.0	26.9	2.0	7.2	8.8	6.8	0.3	5.0	0.0	1.0	0.0	0.0	7.2	0.0	0.0	0.5	0.3	0.4	248.0	1.5	2.4	2.1	4.6	0.0	0.0	0.2	14.6	22.9	34.0	51.5	1.6	48.7	11.9	1.2	36.7	5.6
RRM2B	p53R2	ENSG00000048392	"Ribonucleotide reductase regulatory TP53 inducible subunit M2B"	Q7LG56	8	102204502-102238961	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair, DNA replication"	Oxidoreductase	"Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB006854, HPA028812"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 65: Plasmacytoid DCs - Unknown function"	"Nucleoplasm, Cytosol"		"CAB006854: , HPA028812: AB_10602246"	"unprognostic (7.76e-3)"	"unprognostic (4.14e-2)"	"unprognostic (9.41e-3)"	"unprognostic (3.41e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.28e-1)"	"unprognostic (5.51e-2)"	"unprognostic (1.35e-2)"	"unprognostic (1.66e-1)"	"unprognostic (9.40e-2)"	"unprognostic (1.74e-2)"	"unprognostic (1.03e-1)"	"unprognostic (1.70e-2)"	"unprognostic (4.32e-1)"	"unprognostic (1.47e-1)"	"unprognostic (2.52e-1)"	"unprognostic (7.17e-2)"	11.5	21.2	10.5	11.5	12.1	7.1	12.1	13.6	11.5	12.5	26.5	15.3	15.0	11.6	15.1	11.2	13.5	11.9	16.7	10.1	13.7	24.4	22.6	22.0	20.1	13.6	12.4	12.0	13.5	45.0	10.3	13.8	13.9	15.7	15.5	21.9	10.9	13.8	30.4	11.0	10.1	11.7	14.1	14.3	9.5	9.7	12.6	10.1	39.9	34.9	19.6	11.2	5.4	16.8	15.3	26.5	30.7	18.3	43.7	41.3	24.6	34.8	41.4	18.1	21.0	9.6	11.9	97.5	31.8	38.7	18.5	5.7	15.1	35.2	25.3	15.8	16.2	24.4	10.3	20.9	35.3	7.6	50.0	53.1	66.1	20.2	30.5	43.0	51.8	16.3	18.2	14.6	59.1	15.2	13.1	14.6	17.7	16.5	19.2	8.2	12.7	20.1	43.1	17.1	7.8	15.4	17.9	9.7	21.1	76.3	25.5	17.1	39.4	27.8	53.7	19.6	9.6	15.3	15.3	88.0	41.0	11.5	30.2	15.7	6.3	7.0	2.7	5.4	3.8	6.6	2.3	3.2	7.7	8.6	2.6	2.8	23.1	4.1	11.5	2.2	1.8	3.3	10.5	12.1	13.6	11.5	10.1	13.7	13.6	12.4	13.9	14.1	12.6	16.8	16.2	57.7	29.3	10.1	33.5	19.4	8.2	11.8	34.1	13.5	17.0	9.4	22.8	20.0	23.9	40.5	14.6	13.8	13.9	7.3	25.4	6.8	2.3	36.2	11.1	14.9	29.4	3.8	14.6	8.2	5.9	14.8	6.1	11.8	11.4	11.2	18.5	23.6	12.6	10.1	17.6	9.7	10.2	26.2	39.5	1.4	14.3	23.8	17.8	20.6	18.2	24.5	7.2	16.1	12.1	5.7	5.7	14.7	9.3	10.7	8.1	22.7	39.9	18.3	6.6	16.2	16.8	13.2	14.5	26.2	18.5	4.8	12.2	8.6	12.1	6.7
TAF9	"AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32"	ENSG00000273841	"TATA-box binding protein associated factor 9"	Q16594	5	69364743-69370013	"Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 550.8;Late spermatids: 924.3;Spermatocytes: 370.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA028930, HPA053429, HPA058961, HPA072658"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 31: Spermatids - Spermatogenesis"	Nucleoplasm		"HPA028930: AB_2672832, HPA053429: AB_2682148, HPA058961: AB_2683863, HPA072658: "	"unprognostic (1.25e-3)"	"unprognostic (9.52e-2)"	"unprognostic (1.76e-3)"	"unprognostic (8.38e-3)"	"unprognostic (5.40e-2)"	"unprognostic (1.77e-2)"	"prognostic unfavorable (1.48e-5)"	"unprognostic (1.19e-1)"	"unprognostic (1.69e-1)"	"unprognostic (1.66e-1)"	"unprognostic (9.45e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (9.20e-4)"	"unprognostic (2.58e-1)"	"unprognostic (1.97e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.79e-1)"	42.1	43.5	35.5	31.9	38.6	108.2	46.0	35.4	41.4	28.3	34.4	42.5	34.2	31.5	50.4	37.4	31.1	28.8	52.7	39.2	43.0	38.4	55.7	27.7	46.6	37.1	36.4	37.8	40.8	35.5	50.6	38.0	40.5	33.7	47.5	47.2	34.7	27.7	58.0	36.1	33.2	35.9	36.6	35.0	38.0	140.4	37.7	50.9	28.7	41.7	52.3	50.6	30.3	36.1	107.0	109.3	67.7	121.6	114.4	143.5	179.3	100.1	159.8	172.3	227.0	109.7	135.1	135.9	70.2	146.7	322.2	82.2	92.4	208.1	227.4	65.6	111.0	120.4	154.0	157.8	261.3	118.7	168.3	159.4	137.4	117.1	247.7	122.5	143.1	121.4	122.4	119.8	165.9	147.7	126.1	189.5	82.0	42.6	81.6	83.0	119.7	169.0	152.7	120.7	118.1	82.6	108.3	64.3	192.8	111.3	100.9	175.7	103.3	65.9	98.2	78.2	173.1	93.2	118.3	175.6	101.3	145.7	82.8	149.3	107.8	122.5	52.8	101.3	81.2	90.1	79.7	64.2	83.9	75.4	89.6	73.6	16.0	58.7	88.4	47.0	95.5	134.4	35.5	38.6	35.4	41.4	39.2	43.0	37.1	36.4	40.5	36.6	37.7	36.1	67.4	19.2	29.3	0.0	55.2	174.0	151.4	238.7	39.3	24.1	49.9	81.4	69.3	42.9	108.8	23.9	14.6	118.0	45.1	33.8	90.1	67.1	550.8	47.6	44.9	58.6	30.7	93.2	0.0	80.4	166.7	57.3	36.7	38.1	38.6	53.5	34.6	41.9	107.7	20.2	0.0	49.5	146.5	42.8	99.8	924.3	65.3	55.2	99.6	0.0	66.9	35.1	35.0	0.0	0.0	85.1	37.2	34.3	76.5	87.3	47.4	90.2	85.2	43.0	32.9	49.1	95.5	370.7	78.0	60.7	163.2	104.5	50.7	75.0	64.2	149.6
TNRC6B	KIAA1093	ENSG00000100354	"Trinucleotide repeat containing adaptor 6B"	Q9UPQ9	22	40044817-40335808	"Metabolic proteins, Predicted intracellular proteins"	"RNA-mediated gene silencing, Translation regulation"	RNA-binding	"Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 484.5"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003180	Approved					NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 6: Brain - Smell perception"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 52: Non-specific - Transcription"			"HPA003180: AB_1079196"	"unprognostic (1.45e-1)"	"unprognostic (1.29e-2)"	"unprognostic (1.04e-1)"	"unprognostic (5.88e-2)"	"unprognostic (1.92e-2)"	"unprognostic (3.27e-2)"	"unprognostic (2.13e-1)"	"unprognostic (2.48e-2)"	"unprognostic (9.74e-2)"	"unprognostic (4.93e-2)"	"unprognostic (2.59e-1)"	"unprognostic (8.42e-2)"	"unprognostic (1.84e-3)"	"unprognostic (8.85e-2)"	"unprognostic (7.24e-2)"	"unprognostic (7.00e-2)"	"unprognostic (1.81e-1)"	4.0	3.6	4.5	4.9	6.2	19.5	3.9	22.0	7.6	4.4	13.2	4.2	3.2	4.0	5.8	3.5	3.7	4.4	4.7	3.6	1.1	3.9	5.4	4.9	5.3	3.7	3.5	4.2	3.9	4.7	5.5	3.6	4.2	3.7	3.5	12.7	4.0	2.8	6.4	5.5	5.2	3.7	1.1	5.6	4.3	14.9	3.9	9.2	5.0	5.1	5.9	3.6	4.2	15.7	6.3	9.3	9.4	9.8	6.1	4.3	5.1	4.2	7.7	6.5	7.9	4.2	4.3	11.9	7.4	5.1	7.6	4.3	11.8	8.6	6.8	13.0	9.3	8.8	9.3	5.3	3.0	10.2	12.5	4.8	4.0	10.2	5.1	3.1	9.0	6.7	7.4	10.8	6.1	6.8	6.3	3.2	12.2	4.8	6.7	7.7	9.0	6.0	6.1	10.6	11.4	2.7	10.2	3.6	5.2	8.5	5.1	3.7	10.3	5.7	20.7	5.8	4.0	8.5	8.2	7.8	3.7	5.1	6.8	228.9	32.8	66.2	48.0	19.2	42.4	100.7	50.5	44.5	16.3	134.6	52.8	53.6	484.5	34.7	29.6	104.9	29.5	12.5	4.5	6.2	22.0	7.6	3.6	1.1	3.7	3.5	4.2	1.1	3.9	15.7	114.0	38.5	54.9	260.8	178.8	74.8	70.2	60.8	92.8	248.7	103.4	85.9	153.6	125.8	56.0	69.9	458.7	36.4	171.1	77.8	70.5	59.8	82.5	142.2	91.0	104.4	141.0	203.1	334.1	59.3	20.7	108.4	61.2	85.0	65.9	78.1	120.7	109.7	39.0	341.6	371.8	76.7	65.1	115.9	80.1	72.4	111.9	71.4	65.8	235.2	117.2	127.2	168.9	255.9	304.0	54.4	76.4	127.9	117.8	79.8	93.0	69.0	91.3	356.9	52.6	175.5	95.1	87.7	88.3	56.6	82.1	7.5	149.0	82.6	83.7	59.1
TRPM2	"EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7"	ENSG00000142185	"Transient receptor potential cation channel subfamily M member 2"	O94759	21	44350163-44443081	"Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Calcium transport, Ion transport, Sodium transport, Transport"	"Calcium channel, Ion channel, Sodium channel"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 28.2;brain: 26.4;lymphoid tissue: 18.4"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 52.7;Hofbauer cells: 18.3;Inhibitory neurons: 45.1;Macrophages: 16.7;Microglial cells: 27.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 7.8;plasmacytoid DC: 15.5"	"Group enriched"	"Detected in many"	6	"dendritic cells: 15.5;monocytes: 7.8"	"Cell line enhanced"	"Detected in many"		"HL-60: 41.7;NB-4: 58.6;OE19: 41.3;THP-1: 71.3;U-266/84: 31.8;U-937: 67.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035260	Enhanced					NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 32: U-937 - Innate immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"			"HPA035260: AB_2674540"	"unprognostic (3.61e-2)"	"unprognostic (2.18e-1)"	"unprognostic (7.55e-2)"	"prognostic favorable (9.28e-4)"	"unprognostic (6.49e-2)"	"unprognostic (4.54e-2)"	"unprognostic (5.17e-2)"	"unprognostic (2.23e-1)"	"unprognostic (8.13e-2)"	"unprognostic (2.41e-3)"	"unprognostic (1.24e-1)"	"unprognostic (1.03e-1)"	"prognostic unfavorable (4.39e-6)"	"unprognostic (1.40e-1)"	"unprognostic (3.31e-2)"	"unprognostic (8.88e-3)"	"prognostic favorable (7.59e-4)"	4.8	4.1	14.0	6.7	14.5	28.2	3.0	11.1	26.4	2.1	7.7	3.8	3.6	1.6	0.7	1.6	2.1	4.7	1.8	13.9	11.8	2.5	2.3	5.0	8.0	20.9	14.5	0.9	1.8	1.1	4.8	6.0	20.8	2.7	2.3	0.9	2.3	0.8	0.9	2.3	6.9	2.5	12.2	18.4	2.5	2.7	16.0	3.3	1.8	0.4	4.1	3.5	1.6	17.4	20.8	7.5	0.0	0.1	0.0	0.0	20.9	0.0	0.0	0.6	0.4	0.0	0.0	0.5	24.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	3.6	3.9	0.0	0.0	41.7	2.2	0.0	0.0	0.0	0.0	0.0	0.0	11.3	0.0	0.0	0.0	0.0	6.7	58.6	0.0	41.3	23.5	2.3	7.2	8.0	0.0	0.0	14.4	0.1	0.0	23.5	0.1	0.0	27.7	71.3	0.0	1.2	20.9	0.1	0.7	0.3	31.8	0.1	0.0	67.7	0.0	0.0	7.8	0.0	1.0	2.7	0.5	0.3	0.3	0.4	2.6	1.9	0.3	0.4	0.4	0.5	2.5	15.5	1.3	2.0	14.0	14.5	11.1	26.4	13.9	11.8	20.9	14.5	20.8	12.2	16.0	17.4	2.0	0.0	0.5	1.3	2.0	0.4	0.0	0.0	0.6	1.4	2.8	3.0	1.7	0.0	0.0	0.0	0.0	1.8	9.9	0.8	0.0	0.1	2.1	0.7	0.2	2.7	0.0	0.0	52.7	0.2	8.8	0.5	1.1	1.2	1.3	0.3	0.4	0.4	18.3	0.0	45.1	1.0	0.0	11.0	5.5	2.0	0.6	16.7	0.0	27.2	5.5	0.5	6.2	4.0	1.7	1.2	0.1	0.0	1.4	0.0	0.0	0.3	0.0	1.0	6.6	0.5	0.4	1.0	0.1	0.1	0.3	1.4	4.2	0.0	0.7	0.0
TXN	TRX	ENSG00000136810	Thioredoxin	P10599	9	110243810-110256507	"Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Electron transport, Transcription, Transcription regulation, Transport"	Activator	Allergen	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"esophagus: 1058.8"	"Cell type enriched"	"Detected in all"	4	"monocytes: 15775.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Group enriched"	"Detected in all"	4	"dendritic cells: 1642.2;granulocytes: 1355.4"	"Cell line enhanced"	"Detected in all"		"OE19: 3836.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008678, HPA047478, HPA055752"	Enhanced		Enhanced	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA		16000000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 37: Intestine - Unknown function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 3: Monocytes - Immune response regulation"	"Nucleoplasm, Cytosol"		"CAB008678: AB_1623676, HPA047478: AB_2680063, HPA055752: AB_2682907"	"unprognostic (2.12e-2)"	"unprognostic (1.27e-1)"	"unprognostic (9.77e-2)"	"prognostic favorable (3.40e-6)"	"unprognostic (1.80e-2)"	"unprognostic (2.13e-2)"	"unprognostic (5.52e-3)"	"unprognostic (1.37e-2)"	"unprognostic (1.75e-1)"	"unprognostic (3.36e-2)"	"unprognostic (5.93e-3)"	"unprognostic (1.66e-1)"	"unprognostic (4.96e-3)"	"unprognostic (7.80e-2)"	"unprognostic (8.55e-2)"	"unprognostic (2.99e-2)"	"unprognostic (8.51e-2)"	144.2	127.7	149.9	145.4	155.3	367.5	218.6	154.5	225.4	153.9	140.5	455.2	349.3	130.9	168.4	1058.8	240.7	142.1	90.8	156.2	161.7	430.6	436.0	158.4	131.6	163.3	156.2	83.8	119.1	73.0	61.2	105.8	163.0	113.6	435.0	46.2	391.7	128.9	84.8	240.1	332.2	140.3	158.1	105.4	222.7	36.6	156.4	261.3	93.8	76.4	208.3	218.1	230.8	164.8	672.9	920.0	238.7	265.6	601.0	782.3	352.7	792.5	756.2	555.6	419.4	606.8	785.6	598.9	331.5	754.7	1181.3	1464.8	351.0	1081.1	544.6	887.6	778.5	298.2	804.7	1061.8	684.7	747.2	864.2	556.2	703.5	809.0	607.8	504.7	498.7	369.7	515.9	553.1	775.4	557.1	621.9	1119.7	505.4	3836.3	1110.5	256.6	810.3	696.3	721.7	479.4	520.9	183.7	860.0	687.5	572.7	458.6	661.2	508.6	587.9	556.4	357.3	1050.2	1006.1	271.4	872.5	512.7	804.8	654.4	789.5	484.8	311.2	1355.4	169.2	195.5	165.2	154.2	237.7	207.3	475.7	75.9	87.4	129.3	1212.7	195.0	131.6	1642.2	337.0	279.2	149.9	155.3	154.5	225.4	156.2	161.7	163.3	156.2	163.0	158.1	156.4	164.8	458.7	391.0	298.2	12.4	165.9	1304.5	1072.4	3654.4	435.4	38.0	514.2	752.8	108.5	418.9	1810.0	263.0	20.9	637.2	443.0	1297.7	972.4	1172.8	31.2	1560.7	1465.0	587.0	556.4	388.4	18.2	1341.7	993.1	526.8	662.1	775.9	268.6	247.1	216.0	842.8	571.8	28.6	18.3	1111.2	2191.1	286.1	1752.9	31.6	403.2	682.7	763.1	10.3	15775.8	86.3	128.8	7.5	21.9	1994.7	1227.7	285.5	388.5	2151.2	1439.2	3670.6	1516.8	34.8	144.7	211.8	557.8	10.6	76.3	2725.7	1491.0	468.2	266.6	879.4	1621.8	1742.1
TXN2	MT-TRX	ENSG00000100348	"Thioredoxin 2"	Q99757	22	36467046-36481640	"Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Electron transport, Transport"		"Neurodegeneration, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000994, CAB008681"	Approved		Enhanced	Mitochondria		No	No		84000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB008681: AB_1623682, HPA000994: AB_1080267"	"unprognostic (5.11e-2)"	"unprognostic (4.40e-3)"	"unprognostic (4.40e-3)"	"unprognostic (1.07e-2)"	"unprognostic (5.85e-2)"	"unprognostic (4.28e-2)"	"unprognostic (4.02e-2)"	"unprognostic (5.05e-2)"	"unprognostic (2.15e-1)"	"unprognostic (1.78e-1)"	"unprognostic (3.17e-2)"	"prognostic favorable (2.04e-4)"	"prognostic favorable (1.17e-6)"	"unprognostic (1.49e-2)"	"unprognostic (2.78e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.05e-1)"	60.3	182.3	89.8	45.5	92.4	64.7	58.0	94.6	98.2	57.4	92.4	65.3	84.0	50.0	51.7	79.8	64.1	49.4	122.3	87.9	90.7	91.5	149.5	44.7	59.2	92.9	91.3	75.8	59.2	99.1	43.4	47.3	91.9	59.3	63.6	43.0	59.5	52.5	159.4	60.5	64.3	48.3	91.2	65.7	76.1	48.8	97.0	50.9	67.7	180.1	59.9	59.0	54.0	91.7	52.8	80.4	75.4	126.8	115.2	125.0	81.3	70.8	108.1	114.8	128.7	87.9	52.1	133.3	64.2	116.8	54.5	76.1	151.7	127.4	66.1	93.6	131.8	147.7	91.7	125.4	94.6	189.6	125.8	162.3	98.9	101.9	79.3	99.5	118.2	78.4	157.7	104.1	106.1	80.3	87.5	128.2	60.0	170.3	95.3	75.3	79.5	92.6	116.4	84.8	99.9	98.3	70.2	148.1	125.3	61.3	103.6	165.9	83.7	120.5	95.0	69.8	65.9	81.4	64.2	128.6	111.0	109.5	74.1	30.2	173.5	32.3	102.5	194.3	108.9	140.4	101.2	109.0	223.4	133.8	116.4	108.6	59.3	145.4	170.1	167.1	110.9	224.3	89.8	92.4	94.6	98.2	87.9	90.7	92.9	91.3	91.9	91.2	97.0	91.7	68.9	60.9	53.0	12.1	66.4	83.5	87.7	154.0	108.1	105.6	124.3	137.7	105.4	88.6	82.5	69.9	39.6	213.2	62.8	128.5	303.3	93.0	19.6	45.7	70.6	73.7	89.5	114.0	8.3	106.2	275.8	74.0	75.4	57.2	69.1	148.0	81.0	122.7	173.4	116.1	10.3	132.4	95.6	100.5	80.7	36.8	56.5	80.7	78.2	8.4	91.9	168.9	77.2	9.0	13.5	82.5	104.3	50.8	79.5	52.7	252.2	213.7	49.0	59.4	19.7	61.1	67.1	49.1	42.4	124.5	89.8	207.1	62.4	287.0	179.6	87.1
TYMP	"ECGF1, MNGIE"	ENSG00000025708	"Thymidine phosphorylase"	P19971	22	50525752-50530032	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Angiogenesis, Chemotaxis, Differentiation"	"Developmental protein, Glycosyltransferase, Growth factor, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Exocrine glandular cells: 643.9;Hofbauer cells: 477.4;Macrophages: 561.7;monocytes: 2174.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"classical monocyte: 135.8;eosinophil: 74.9;intermediate monocyte: 98.4;myeloid DC: 39.5;neutrophil: 114.1;non-classical monocyte: 77.1"	"Group enriched"	"Detected in all"	10	"dendritic cells: 39.5;granulocytes: 114.1;monocytes: 135.8"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 40.0;HHSteC: 95.2;Karpas-707: 68.6;U-266/70: 68.6"	"Not detected"	"Not detected"							"HPA000530, HPA001072, CAB002518"	Enhanced		Approved	"Nuclear bodies,Golgi apparatus,Cytosol"		NA	NA		11000000	"Cluster 52: Eosinophils - Transcription"	"Cluster 64: Macrophages - Immune response"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 3: Monocytes - Immune response regulation"	"Nuclear bodies, Golgi apparatus"	Cytosol	"CAB002518: AB_563953, HPA000530: AB_2666017, HPA001072: AB_1080274"	"unprognostic (7.02e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.61e-1)"	"prognostic favorable (4.34e-5)"	"unprognostic (7.60e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.40e-1)"	"unprognostic (7.17e-2)"	"unprognostic (4.64e-2)"	"unprognostic (1.33e-1)"	"unprognostic (3.31e-2)"	"unprognostic (2.17e-1)"	"prognostic unfavorable (3.50e-8)"	"unprognostic (1.32e-1)"	"unprognostic (4.02e-2)"	"unprognostic (1.52e-2)"	"unprognostic (4.60e-2)"	46.8	19.5	6.1	77.7	6.0	22.0	37.9	7.1	7.9	32.2	12.7	20.4	26.1	7.8	0.5	58.5	30.0	7.2	26.7	6.4	8.6	38.2	82.0	63.4	31.5	22.1	18.3	4.0	13.8	4.5	8.8	15.4	15.9	21.0	3.6	0.0	40.0	5.6	10.7	24.5	32.5	9.1	10.9	86.1	31.2	3.0	18.0	15.6	25.4	1.6	15.3	22.9	27.0	12.2	27.0	2.5	0.4	0.8	1.8	2.2	5.1	3.7	0.5	6.1	17.4	0.1	40.0	1.8	4.1	5.8	1.3	21.0	0.2	1.0	0.0	9.0	16.5	1.8	3.9	3.5	95.2	1.3	26.9	4.7	4.6	5.4	0.0	0.1	0.1	0.5	2.8	68.6	0.9	1.9	1.5	9.9	0.6	1.9	9.1	5.7	0.4	35.1	0.3	1.2	0.7	5.6	22.9	17.3	6.5	0.2	4.2	13.8	6.7	0.8	4.7	1.5	1.5	68.6	15.9	5.7	1.9	1.5	1.6	19.5	135.8	74.9	2.0	98.4	1.2	6.7	2.9	1.2	39.5	6.9	1.6	1.3	114.1	9.5	77.1	9.3	3.1	10.1	6.1	6.0	7.1	7.9	6.4	8.6	22.1	18.3	15.9	10.9	18.0	12.2	122.6	12.8	29.0	0.3	122.9	58.5	57.4	169.9	53.5	3.4	101.5	90.8	3.2	50.1	88.6	33.1	4.2	17.2	65.8	154.8	29.4	340.2	2.2	55.7	56.0	55.7	16.8	19.6	0.3	643.9	300.8	81.9	38.7	59.2	53.4	3.0	38.2	93.0	477.4	0.0	0.4	50.2	24.4	371.8	409.4	8.7	5.0	561.7	113.8	4.7	2174.6	2.9	71.1	0.5	0.2	364.0	86.4	1.9	102.1	109.8	214.5	105.1	78.0	6.6	26.3	93.3	62.4	1.5	8.0	71.7	56.7	33.5	62.5	3.7	51.1	76.0
UCK1	"FLJ12255, URK1"	ENSG00000130717	"Uridine-cytidine kinase 1"	Q9HA47	9	131523801-131531264	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA050969, HPA070526"	Approved		Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Nucleoli	"HPA050969: AB_2681294, HPA070526: "	"unprognostic (2.20e-1)"	"prognostic favorable (3.19e-4)"	"unprognostic (1.16e-2)"	"unprognostic (1.74e-3)"	"unprognostic (7.29e-2)"	"unprognostic (1.43e-1)"	"unprognostic (8.71e-2)"	"unprognostic (1.78e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.18e-1)"	"unprognostic (1.36e-3)"	"unprognostic (1.54e-1)"	"prognostic favorable (2.21e-7)"	"unprognostic (5.11e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.07e-1)"	21.5	25.3	40.3	10.2	41.2	16.4	20.4	40.5	45.2	21.2	37.0	26.0	11.8	20.2	18.7	21.2	19.9	12.2	28.1	38.1	39.2	29.3	52.7	17.2	15.1	41.6	41.4	22.2	29.8	22.6	24.2	14.3	40.0	26.9	9.3	13.5	25.6	17.3	43.9	19.1	18.0	11.2	40.7	20.9	24.9	20.4	42.1	17.5	23.4	26.8	11.5	20.9	17.2	40.9	13.9	30.0	33.9	43.8	23.6	16.7	28.9	22.0	32.1	37.0	28.0	30.1	12.4	15.0	12.9	26.4	28.9	26.3	31.9	28.0	15.8	27.7	29.8	14.0	46.3	19.2	33.6	23.2	19.9	18.8	25.8	29.9	21.6	22.4	23.0	36.3	17.9	11.2	27.6	55.2	31.9	11.8	40.4	27.0	29.6	30.1	52.5	25.1	24.1	13.0	45.7	28.9	31.8	23.9	34.3	15.4	46.6	13.5	17.1	40.9	20.7	25.7	21.7	22.7	31.3	19.4	20.3	16.0	29.1	2.1	5.5	9.0	7.3	7.2	9.8	7.4	8.5	6.4	5.2	8.0	11.3	5.6	3.6	7.0	2.6	5.9	12.0	5.6	40.3	41.2	40.5	45.2	38.1	39.2	41.6	41.4	40.0	40.7	42.1	40.9	13.6	16.0	5.0	7.8	12.4	14.3	10.3	9.9	12.5	18.0	16.2	20.1	14.0	4.3	6.2	14.7	8.4	33.8	12.0	20.4	29.4	22.7	21.9	9.0	10.2	14.3	12.1	3.0	4.7	26.2	17.5	15.7	6.6	9.2	2.5	16.2	13.2	20.5	26.4	26.9	6.1	11.6	16.2	10.0	13.4	33.3	17.7	14.0	16.0	4.7	20.4	22.0	9.2	2.0	6.0	18.6	12.3	19.9	8.0	14.3	21.1	31.6	3.1	13.1	19.7	12.4	17.2	32.8	33.4	11.8	12.5	25.7	10.0	14.9	14.8	8.5
UCK2	UMPK	ENSG00000143179	"Uridine-cytidine kinase 2"	Q9BZX2	1	165827614-165911618	"Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 110.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA057128			Approved	Nucleoplasm		NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 52: Non-specific - Ribosome"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	Nucleoplasm		"HPA057128: AB_2683346"	"unprognostic (5.37e-2)"	"unprognostic (1.75e-2)"	"unprognostic (2.51e-1)"	"unprognostic (1.20e-2)"	"unprognostic (4.54e-2)"	"unprognostic (6.83e-3)"	"prognostic unfavorable (9.22e-8)"	"prognostic unfavorable (4.98e-4)"	"prognostic unfavorable (6.70e-4)"	"unprognostic (3.04e-2)"	"unprognostic (1.49e-1)"	"unprognostic (1.13e-2)"	"prognostic unfavorable (5.12e-13)"	"unprognostic (2.49e-3)"	"unprognostic (1.14e-1)"	"unprognostic (2.01e-3)"	"unprognostic (1.83e-1)"	12.8	6.0	5.9	9.2	6.0	11.8	15.3	8.9	7.7	8.3	2.5	14.5	13.9	8.0	15.2	17.4	7.5	5.0	9.2	7.2	7.1	7.0	10.6	9.9	8.5	8.0	8.9	5.5	16.0	4.8	7.4	28.0	9.9	6.8	14.1	3.7	13.1	8.4	17.0	13.9	13.2	8.5	5.7	5.9	11.2	6.0	6.2	17.7	5.2	10.8	10.6	14.2	9.9	6.0	66.1	67.7	36.6	34.4	20.2	32.9	49.3	63.4	59.7	86.7	92.2	70.6	75.3	32.3	43.5	57.6	35.2	46.3	88.6	106.2	72.3	51.3	40.8	40.2	52.3	81.8	56.2	72.1	29.2	35.0	52.1	176.6	111.7	21.5	60.8	73.6	95.3	43.0	78.1	54.1	63.6	49.4	103.4	104.7	54.5	27.8	37.6	112.5	43.5	37.6	51.5	58.3	47.2	104.4	48.8	83.3	62.5	65.9	32.9	41.4	52.1	50.3	71.9	49.8	84.9	116.0	36.7	50.1	33.3	0.8	5.9	0.1	1.5	3.7	3.6	3.3	1.6	2.5	15.1	4.4	0.1	1.4	0.1	3.8	4.2	13.9	2.2	1.9	5.9	6.0	8.9	7.7	7.2	7.1	8.0	8.9	9.9	5.7	6.2	6.0	10.2	0.0	1.1	10.7	6.6	22.9	29.6	18.3	19.9	4.2	22.4	26.2	5.7	8.6	8.8	9.2	0.0	4.4	12.9	41.5	7.9	14.7	110.4	8.7	12.1	22.3	6.7	10.7	32.8	22.2	60.1	12.4	17.3	11.4	0.0	15.4	5.0	5.8	13.0	0.0	33.1	16.1	14.2	4.1	10.2	56.2	6.5	7.9	10.6	30.0	13.5	4.5	9.2	19.6	23.3	54.8	16.1	3.4	25.8	33.0	31.4	6.7	4.5	4.6	0.0	23.0	15.3	5.6	12.0	26.9	29.7	26.4	4.1	5.4	20.4	22.3
UCKL1	"FLJ20517, URKL1"	ENSG00000198276	"Uridine-cytidine kinase 1 like 1"	Q9NWZ5	20	63939829-63956416	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Host-virus interaction"	"Kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Rod photoreceptor cells: 148.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA004722, HPA004769"	Approved		Approved	"Endoplasmic reticulum"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 46: Photoreceptor cells - Phototransduction"	"Endoplasmic reticulum"		"HPA004722: AB_1080455, HPA004769: AB_1080453"	"unprognostic (1.03e-1)"	"unprognostic (2.77e-2)"	"unprognostic (2.64e-1)"	"unprognostic (8.34e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.20e-1)"	"unprognostic (1.99e-2)"	"unprognostic (1.87e-1)"	"unprognostic (2.45e-1)"	"unprognostic (1.29e-1)"	"prognostic favorable (4.42e-4)"	"unprognostic (5.87e-2)"	"unprognostic (3.18e-2)"	"unprognostic (9.11e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.01e-1)"	"unprognostic (5.26e-3)"	41.9	47.3	21.2	17.4	23.2	24.7	44.0	32.0	33.2	53.7	24.4	46.9	33.5	41.9	7.2	50.4	49.8	11.9	57.1	20.4	21.2	55.1	55.6	40.6	21.2	23.9	21.5	74.9	46.3	17.2	52.3	17.9	23.7	49.4	8.7	55.9	43.4	17.6	61.1	43.0	51.8	9.6	19.4	64.7	37.2	25.7	22.7	15.9	59.0	36.6	11.0	40.1	54.0	31.4	29.2	30.3	25.5	34.2	18.4	15.6	40.9	22.8	15.4	46.2	23.0	72.8	22.0	29.3	37.5	14.9	31.6	46.7	20.0	31.4	9.2	12.3	33.6	22.2	67.8	108.1	20.3	38.2	40.8	21.9	27.6	18.5	15.1	18.3	21.5	28.4	32.1	30.3	14.6	37.4	45.1	66.3	18.9	23.0	70.0	45.4	19.2	51.0	19.1	41.4	60.3	35.3	32.9	31.8	36.2	12.7	33.4	34.1	24.2	48.7	18.2	32.1	30.1	31.5	18.1	13.6	25.0	27.1	18.8	8.0	11.4	9.9	18.3	19.7	21.0	31.0	17.8	15.8	13.3	17.1	10.1	12.4	1.8	8.5	22.2	7.6	20.8	12.1	21.2	23.2	32.0	33.2	20.4	21.2	23.9	21.5	23.7	19.4	22.7	31.4	31.7	25.6	8.3	17.0	24.1	18.9	21.4	29.9	14.8	30.7	13.5	17.3	20.3	18.6	17.7	9.2	83.4	31.2	16.8	24.7	23.5	19.4	2.4	18.2	17.0	19.4	21.5	5.5	7.8	11.1	23.6	17.5	25.0	22.7	13.3	21.1	13.6	12.4	17.6	20.2	9.7	21.2	32.6	11.4	16.4	3.7	17.7	14.5	10.6	4.7	17.0	18.5	12.3	10.1	12.2	17.5	27.4	20.7	21.4	17.8	38.7	16.1	11.3	148.0	26.3	16.2	30.1	12.7	12.4	22.5	19.0	33.4	22.0	28.4	24.3	19.2
URAD	PRHOXNB	ENSG00000183463	"Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase"	A6NGE7	13	27977717-27988693	"Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Purine metabolism"	"Decarboxylase, Lyase"		"Evidence at transcript level"	"Evidence at transcript level"			"Tissue enriched"	"Detected in some"	14	"intestine: 25.1"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 44.4;Intestinal goblet cells: 110.6;Paneth cells: 43.3;Proximal enterocytes: 196.3;Undifferentiated cells: 54.7"	"Cancer enriched"	"Detected in some"	15	"colorectal cancer: 7.4"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	12	"BEWO: 2.6;CACO-2: 2.4"									HPA038972	Uncertain					NA	NA				"Cluster 9: Intestine - Unknown function"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 45: Enterocytes - Digestion"			"HPA038972: AB_10671869"			"unprognostic (2.00e-1)"											"unprognostic (1.05e-1)"	"unprognostic (5.21e-2)"			0.2	0.0	0.0	1.7	0.0	0.0	0.2	0.7	0.1	0.0	0.0	25.1	7.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.0	0.0	0.0	0.0	0.0	0.0	17.0	0.3	0.1	0.0	0.0	0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.0	0.0	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.1	0.0	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	44.4	3.9	0.1	0.3	0.0	0.0	0.0	10.7	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	110.6	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.1	0.0	43.3	0.0	0.0	0.0	196.3	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.3	0.0	54.7	0.0
XDH	"XO, XOR"	ENSG00000158125	"Xanthine dehydrogenase"	P47989	2	31334321-31414742	"Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		Oxidoreductase	"Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"breast: 42.2;intestine: 49.5;liver: 68.5"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 262.1;Distal enterocytes: 143.5;Hepatocytes: 46.9;Paneth cells: 48.8;Proximal enterocytes: 96.8"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 8.2;HBEC3-KT: 20.0;hTERT-HME1: 31.0;U-251 MG: 8.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"HPA062641, HPA069323"	Supported		Uncertain	Nucleoplasm,Nucleoli	"Intracellular and membrane"	No	No		77000		"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 30: Mammary glandular cells - Lactation"	Nucleoplasm	Nucleoli	"HPA062641: AB_2684816, HPA069323: AB_2686121"	"unprognostic (8.58e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.08e-2)"	"unprognostic (7.06e-2)"	"unprognostic (4.38e-3)"	"unprognostic (7.48e-3)"	"unprognostic (3.55e-1)"	"unprognostic (3.60e-2)"	"unprognostic (3.95e-3)"	"unprognostic (3.51e-2)"	"unprognostic (1.24e-6)"	"unprognostic (2.25e-1)"	"unprognostic (5.25e-2)"	"unprognostic (2.54e-1)"	"prognostic favorable (8.73e-6)"	0.2	0.0	0.0	4.8	0.0	0.1	42.2	0.3	0.0	0.3	0.4	11.1	44.9	0.9	2.3	9.8	0.1	4.5	0.0	0.0	0.0	0.2	68.5	0.3	0.0	0.0	0.0	0.0	0.4	0.0	1.5	0.1	0.1	1.3	9.5	0.1	3.6	0.1	0.5	1.1	49.5	0.7	0.0	0.0	3.2	0.1	0.0	0.2	0.3	0.0	2.3	2.7	2.0	0.1	2.0	0.4	0.0	0.0	0.0	0.1	0.1	8.2	4.7	1.0	1.4	0.3	2.3	0.1	1.6	0.3	0.8	4.2	0.0	20.0	1.0	1.0	0.0	0.0	0.2	0.1	0.0	0.1	0.0	0.1	1.8	1.1	31.0	0.4	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.2	0.4	1.2	0.2	0.0	1.4	4.5	5.7	5.2	0.0	0.1	0.1	0.3	0.0	1.7	0.0	0.0	0.0	3.8	2.4	0.2	8.9	2.5	0.1	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	1.6	0.0	2.4	0.0	0.2	0.5	6.0	5.5	2.8	0.3	262.1	6.5	0.4	2.8	3.6	0.0	0.0	0.3	1.1	143.5	0.0	3.9	0.3	7.9	2.8	0.3	11.9	0.0	0.2	8.2	0.6	0.2	2.0	37.0	0.0	0.0	1.4	46.9	0.0	0.0	0.2	8.4	2.0	1.9	0.7	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	10.7	48.8	0.0	0.0	2.2	96.8	0.0	1.0	0.7	0.0	0.3	0.7	0.0	0.2	1.2	0.1	0.4	0.7	0.2	22.2	16.9