Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "adrenal gland: 3039.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 649.2;Cytotrophoblasts: 1105.1;Extravillous trophoblasts: 1284.9;Ionocytes: 697.8;Syncytiotrophoblasts: 2022.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 1667.3;BJ hTERT+: 3096.2;RPTEC TERT1: 1447.8;U-87 MG: 1343.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935" "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.00e-4)" 65.1 3039.1 83.1 38.4 89.3 21.9 52.3 91.8 97.4 41.4 80.9 40.1 20.5 42.4 44.0 28.2 38.7 40.2 208.2 84.1 92.5 218.0 19.3 55.0 74.6 101.6 96.9 60.5 34.4 111.2 76.5 203.7 104.9 34.4 30.9 36.5 41.9 332.7 330.0 26.6 50.8 39.6 91.4 62.8 51.4 44.9 88.7 54.9 44.3 396.9 62.5 67.3 35.0 101.4 184.2 1667.3 186.5 261.4 785.9 212.3 494.6 177.2 3096.2 259.3 335.0 75.8 170.6 0.0 79.2 301.5 1143.3 78.6 204.0 175.3 206.6 65.2 168.2 93.4 225.0 230.1 1117.9 0.1 0.8 196.9 133.4 367.6 98.3 252.8 370.3 181.1 0.1 62.4 292.4 3.5 283.3 131.0 309.2 13.9 1.8 292.9 116.5 138.8 1447.8 915.5 137.1 301.6 1261.5 1.5 134.3 121.3 0.6 140.6 289.6 254.5 116.0 22.7 195.6 168.2 196.9 470.0 1343.5 0.7 153.0 125.7 106.4 5.6 147.6 72.3 135.2 133.0 124.7 144.5 145.3 121.7 162.9 156.7 8.5 119.7 39.2 20.4 94.9 230.2 83.1 89.3 91.8 97.4 84.1 92.5 101.6 96.9 104.9 91.4 88.7 101.4 34.1 12.8 19.4 9.1 50.3 20.6 55.3 66.1 20.5 36.2 11.7 27.9 202.4 25.8 26.4 649.2 8.4 1105.1 35.1 2.3 164.4 112.7 5.0 6.1 20.9 50.9 31.0 20.2 10.5 41.5 1284.9 100.3 20.4 5.9 53.8 59.8 82.1 2.6 394.1 72.3 18.7 15.1 697.8 172.8 53.9 14.5 79.2 127.7 30.2 14.0 76.3 49.3 66.9 5.5 12.4 51.0 4.5 77.5 72.6 25.6 0.3 60.2 24.9 24.1 59.2 98.9 54.5 22.6 100.2 10.5 11.6 2022.4 49.9 70.5 6.7 54.2 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 185.7 14.3 12.3 13.5 16.5 5.8 116.2 16.0 11.5 12.9 6.9 23.2 25.3 6.6 6.6 103.9 11.5 65.7 135.5 10.9 18.7 45.4 623.2 28.9 4.7 22.1 18.4 15.5 23.3 0.8 9.7 1.7 23.2 17.3 12.2 11.5 73.7 12.5 120.4 35.3 23.4 8.7 19.6 4.1 142.9 13.0 22.2 4.6 46.7 27.3 7.8 71.1 31.3 20.3 0.0 429.6 2.4 426.7 2988.3 358.2 0.2 13.7 95.9 5.4 4.1 8.4 0.5 0.0 6.1 97.7 72.5 3.6 1.6 22.4 2.5 0.1 0.2 12.6 65.6 5415.7 30.0 1.8 0.0 183.9 27.3 44.2 26.7 0.4 10.2 2.9 95.8 0.4 74.7 2.4 0.1 0.4 1.2 2297.1 1.5 0.1 0.8 4.2 24.3 81.4 0.4 1.7 23.8 0.7 0.8 1.3 0.5 7.8 85.3 36.0 2.3 97.6 4.5 1.6 0.5 0.3 129.3 12.1 0.9 1.5 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 0.1 0.2 12.3 16.5 16.0 11.5 10.9 18.7 22.1 18.4 23.2 19.6 22.2 20.3 21.6 67.3 34.4 2.0 2.4 21.2 27.8 253.8 262.4 3.1 7.6 1.0 3.2 284.5 144.5 62.5 0.0 0.1 0.2 5.9 13.7 67.0 24.0 3.3 1.7 17.1 1.8 52.6 3.4 328.0 0.1 176.3 139.1 4.6 4.5 0.8 21.0 597.7 0.4 0.0 3.1 6.8 20.3 16.1 15.6 9.9 151.6 3.3 106.7 13.1 4.6 51.5 0.0 4.5 0.5 120.2 3.6 147.4 0.4 41.3 20.2 61.9 72.2 4.5 0.0 16.4 24.3 1.9 1.1 229.3 20.5 0.1 2.1 6.4 20.3 306.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 613.3" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 6.6;OE19: 2.9" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 0.4 41.8 0.0 0.0 0.0 0.3 717.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.2 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 37.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.2 0.0 0.8 0.0 13.5 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 13.6 613.3 0.0 0.0 0.0 0.6 0.0 14.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.2 1.0 1.5 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051371: AB_2681459" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.75e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.45e-3)" "unprognostic (2.90e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.19e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" 11.2 38.4 10.5 5.6 11.0 5.5 12.0 10.9 13.1 12.1 15.5 13.0 10.2 10.0 11.3 10.1 10.5 6.7 32.0 10.8 11.1 23.0 25.7 7.4 6.3 10.6 10.6 11.5 7.0 25.1 15.9 8.0 10.6 12.6 9.5 5.8 11.1 9.9 38.6 9.3 10.8 9.8 10.7 11.3 13.4 22.0 11.0 7.3 12.3 42.6 7.0 13.6 10.5 11.1 12.2 21.7 11.1 25.7 13.2 10.7 15.4 14.8 13.6 21.8 18.4 16.4 21.0 10.7 13.7 15.3 15.0 19.1 16.6 14.8 20.6 16.3 13.3 7.2 12.8 14.3 18.0 7.2 24.9 18.1 19.2 19.9 19.5 14.1 13.9 21.5 6.4 9.6 19.2 33.3 12.4 11.7 4.0 24.8 26.0 11.7 14.1 7.6 22.9 15.2 16.6 8.8 25.2 21.5 14.6 7.2 36.4 13.3 9.4 24.8 22.9 19.0 10.8 8.9 9.0 9.0 13.7 10.6 17.1 5.4 11.3 9.2 11.3 14.2 11.3 10.3 11.2 11.3 12.1 5.3 15.6 9.4 2.3 14.5 13.1 8.9 7.6 8.5 10.5 11.0 10.9 13.1 10.8 11.1 10.6 10.6 10.6 10.7 11.0 11.1 11.9 25.6 25.5 6.2 11.4 4.7 8.1 26.9 6.8 18.9 12.3 12.4 10.3 11.5 23.1 12.9 12.5 26.3 4.1 8.3 19.6 10.8 167.0 14.1 11.0 9.1 4.8 7.4 10.0 10.9 12.6 11.9 12.2 9.9 25.3 13.9 11.4 14.7 16.2 20.2 10.0 9.7 20.3 5.4 4.2 49.5 10.8 7.5 10.6 3.7 9.6 12.0 15.5 5.0 8.4 8.6 8.4 12.4 10.6 6.0 23.3 41.3 15.8 28.1 19.7 10.5 20.5 24.7 21.0 11.5 6.0 23.8 11.9 39.9 9.4 7.1 CYP11A1 "CYP11A, P450SCC" ENSG00000140459 "Cytochrome P450 family 11 subfamily A member 1" P05108 15 74337759-74367646 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Steroidogenesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "adrenal gland: 1009.9" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 345.1;Peritubular cells: 173.8;Syncytiotrophoblasts: 1452.0;Theca cells: 637.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "basophil: 10.2" "Lineage enriched" "Detected in single" 48 "granulocytes: 10.2" "Group enriched" "Detected in some" 5 "BEWO: 55.2;HEL: 46.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 1.8;hippocampal formation: 1.1;hypothalamus: 1.3;midbrain: 4.5;pons: 1.1" HPA016436 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA016436: AB_1847423" "unprognostic (8.89e-2)" "unprognostic (6.96e-2)" "unprognostic (4.95e-3)" "unprognostic (9.31e-2)" "unprognostic (9.42e-4)" "unprognostic (1.90e-1)" "unprognostic (1.55e-3)" "unprognostic (8.06e-2)" "unprognostic (3.04e-1)" "unprognostic (2.95e-1)" "unprognostic (1.77e-2)" "unprognostic (5.45e-2)" "unprognostic (9.66e-4)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (3.04e-2)" "unprognostic (7.95e-2)" 2.0 1009.9 2.0 0.6 2.1 0.1 1.9 2.3 2.0 2.0 3.5 0.8 0.3 1.6 0.8 6.3 2.4 0.4 1.4 2.0 2.1 0.6 3.6 0.6 0.1 2.8 2.5 38.9 0.3 0.0 2.8 25.2 2.8 1.2 0.2 0.7 1.2 0.5 2.5 0.6 0.8 0.9 2.6 4.9 0.9 23.0 1.9 0.3 0.3 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.0 0.2 0.0 0.4 55.2 0.1 0.0 0.4 0.1 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 46.8 1.2 0.5 0.2 0.0 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 11.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 2.1 2.3 2.0 2.0 2.1 2.8 2.5 2.8 2.6 1.9 1.9 0.1 0.0 0.0 6.2 0.0 0.3 0.0 0.0 34.1 0.1 0.6 0.9 1.2 2.8 0.0 0.0 0.0 144.6 0.0 0.0 1.9 0.0 1.6 0.2 4.9 0.8 0.0 0.0 0.2 0.0 345.1 10.0 0.0 0.2 0.0 41.3 0.0 3.6 22.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 48.7 0.4 0.0 1.0 0.6 6.2 0.0 0.0 0.2 0.5 0.0 173.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.2 4.6 2.8 8.7 0.0 1452.0 0.0 637.4 0.0 0.0 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 877 "adrenal gland: 3686.5" "Group enriched" "Detected in some" 113 "Early spermatids: 53.3;Late spermatids: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.2 3686.5 0.1 0.9 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.4 0.3 0.0 0.9 0.5 0.3 0.0 0.1 0.1 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.4 4.2 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP11B2 "ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo" ENSG00000179142 "Cytochrome P450 family 11 subfamily B member 2" P19099 8 142910559-142917843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 603 "adrenal gland: 179.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Uncertain Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.0 179.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Steroidogenesis "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "adrenal gland: 8229.5" "Cell type enriched" "Detected in some" 17 "Theca cells: 1871.0" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;SCLC-21H: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA048533: AB_2680432" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" 0.4 8229.5 0.0 2.1 0.0 0.0 0.4 0.1 0.1 1.1 0.0 0.5 0.0 0.8 0.1 0.9 1.0 0.4 1.0 0.0 0.0 52.9 6.7 1.4 0.0 0.0 0.1 16.6 1.7 10.5 0.7 0.0 0.0 0.7 0.0 0.2 3.4 0.0 1.0 0.7 0.6 0.0 0.0 0.9 1.3 98.3 0.0 0.0 2.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 2.2 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.7 0.0 0.0 1.8 0.0 0.4 0.1 0.1 21.5 0.0 41.6 0.1 0.0 0.7 0.0 2.7 0.1 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.4 6.1 0.1 1.7 0.1 0.0 0.0 0.6 0.7 10.6 1.8 0.9 0.0 0.0 0.1 0.2 3.1 0.5 0.1 0.7 0.0 0.0 0.0 0.3 0.0 104.3 0.0 1.2 0.0 1.2 0.6 0.3 0.1 0.0 0.0 0.3 0.4 1871.0 0.0 0.1 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.1;urinary bladder: 63.6" "Cell type enhanced" "Detected in some" "Adipocytes: 21.9;Endothelial cells: 13.7;Glandular and luminal cells: 5.9;Hepatocytes: 9.9;Urothelial cells: 16.4" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 36.9;hTCEpi: 19.5;HUVEC TERT2: 19.1;SK-BR-3: 14.7;SuSa: 35.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" 18.5 0.6 0.2 0.0 0.2 0.0 14.7 0.1 0.3 3.6 0.0 2.0 0.6 2.4 0.6 1.9 1.2 0.7 10.7 0.2 0.4 1.4 66.1 12.2 0.0 0.3 0.4 0.5 0.6 0.0 0.5 0.3 0.3 0.7 0.1 0.3 1.8 0.6 4.1 13.9 19.8 0.0 0.1 0.1 1.8 0.3 0.2 0.2 2.0 0.2 0.1 63.6 2.2 0.1 0.3 2.1 0.2 0.0 0.5 0.1 11.7 0.0 0.1 0.7 0.3 36.9 1.6 0.3 9.6 0.0 8.8 11.4 0.7 7.3 0.3 0.0 1.0 0.5 2.6 5.5 0.2 0.3 11.5 0.0 19.5 0.3 1.4 0.4 19.1 0.3 2.3 0.3 0.1 0.7 0.1 0.4 0.2 12.1 2.9 1.2 0.0 0.4 0.0 2.4 0.6 0.3 1.7 14.7 3.8 35.6 0.4 0.2 1.0 1.6 0.5 5.2 0.0 0.7 0.2 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.4 0.3 0.4 0.3 0.1 0.2 0.1 21.9 0.0 0.0 0.0 0.1 0.5 2.4 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 3.4 1.1 13.7 0.0 0.0 0.1 0.2 0.0 0.2 0.0 5.9 0.0 0.0 0.0 9.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 16.4 CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 313 "liver: 513.4" "Cell type enriched" "Detected in some" 57 "Hepatocytes: 85.7" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-BR-3: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" 0.2 0.3 0.5 0.2 0.5 1.0 0.1 1.6 0.8 0.0 0.2 0.0 0.2 0.2 0.4 0.1 0.2 0.2 0.1 0.5 0.5 0.2 513.4 0.4 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.3 0.3 0.6 0.2 0.0 0.1 0.3 0.2 0.3 0.6 0.1 1.4 0.0 0.1 0.1 0.0 1.3 0.4 0.3 0.8 0.5 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.4 0.8 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.4 0.9 0.6 0.1 0.0 0.7 0.3 0.1 0.1 0.0 0.0 0.3 0.1 1.3 0.7 1.3 0.0 0.2 0.9 0.3 0.4 0.3 0.2 0.9 0.8 0.3 0.1 0.7 0.7 0.3 0.6 2.3 0.1 0.6 0.5 0.2 0.2 0.3 0.4 0.3 0.3 0.3 0.2 0.5 0.3 0.9 0.3 1.5 0.3 0.5 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.2 2.1 0.4 0.2 0.4 0.1 0.1 0.5 0.5 1.6 0.8 0.5 0.5 0.6 0.5 0.6 0.1 0.6 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 85.7 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSG00000231852 "Cytochrome P450 family 21 subfamily A member 2" P08686 6 32038327-32041644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Steroidogenesis "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "adrenal gland: 2041.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.9" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HDLM-2: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048979, HPA053371" Enhanced NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA048979: AB_2680584, HPA053371: AB_2682131" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-4)" "unprognostic (2.58e-1)" "unprognostic (2.97e-1)" "unprognostic (2.93e-2)" "unprognostic (2.76e-2)" "unprognostic (8.75e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (6.67e-7)" "unprognostic (7.39e-2)" "unprognostic (5.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.82e-1)" 2.0 2041.7 0.0 0.0 0.0 0.0 1.5 0.0 0.6 1.9 0.0 2.5 0.0 1.5 0.6 0.6 2.4 0.0 2.9 0.0 0.0 7.0 44.8 0.8 0.0 0.0 0.0 4.3 0.9 0.0 1.9 0.0 0.0 1.9 0.0 0.0 4.0 0.0 0.3 0.7 1.1 0.0 0.0 5.5 0.8 0.8 0.0 0.0 2.3 0.0 0.0 2.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.4 2.4 0.5 0.3 1.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.8 0.9 1.8 0.0 0.1 0.0 0.0 1.6 0.0 0.2 1.3 0.4 0.0 15.9 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.6 0.1 1.8 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 2.0 1.2 0.6 0.0 0.3 0.6 0.6 0.4 0.0 0.0 0.0 0.3 1.0 0.0 0.0 CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "liver: 2.0" "Group enriched" "Detected in some" 8 "Club cells: 2.0;Early spermatids: 4.2;Late spermatids: 3.7" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CYP2A6 "CPA6, CYP2A, CYP2A3" ENSG00000255974 "Cytochrome P450 family 2 subfamily A member 6" P11509 19 40843541-40850447 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 171 "liver: 1612.0" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 322.3" "Cancer enriched" "Detected in some" 12 "liver cancer: 281.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (4.10e-1)" "unprognostic (5.05e-2)" "unprognostic (2.64e-2)" "prognostic favorable (5.38e-5)" "unprognostic (4.98e-3)" "unprognostic (4.86e-2)" "unprognostic (6.23e-2)" "unprognostic (5.20e-2)" "unprognostic (1.95e-1)" "unprognostic (2.25e-2)" "unprognostic (8.83e-3)" "unprognostic (2.46e-1)" "unprognostic (3.07e-2)" "unprognostic (2.55e-1)" 0.6 0.2 0.0 0.0 0.1 0.0 9.4 0.0 0.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 1612.0 0.3 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.3 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.2 0.0 0.0 0.4 0.3 0.2 5.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 11.4 322.3 0.0 0.0 0.1 0.0 0.0 14.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 1.5 CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 71 "liver: 152.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 195.3" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.6 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 152.5 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 24.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 11.0 195.3 0.0 0.0 0.1 0.8 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.9 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 320.0" "Group enriched" "Detected in many" 35 "Hepatocytes: 512.8;Proximal enterocytes: 465.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.8" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.2 0.0 0.3 0.3 0.1 0.8 0.2 0.1 0.3 0.3 3.7 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.3 320.0 0.1 0.1 0.2 0.0 0.2 0.8 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 11.7 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.8 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.0 1.1 5.5 0.7 0.5 0.7 1.3 2.8 7.3 1.1 1.4 0.4 2.8 0.7 1.8 2.1 0.1 0.6 2.9 1.9 0.7 3.1 0.8 0.6 0.6 1.2 0.0 6.5 0.6 0.1 0.3 4.1 1.4 0.0 0.7 5.7 512.8 0.1 11.8 9.4 7.6 0.0 5.6 0.0 13.6 0.0 0.4 0.0 0.0 0.1 0.7 0.0 5.0 4.9 0.7 11.3 1.5 0.4 0.6 465.2 0.5 1.3 2.3 0.0 0.4 2.1 0.8 0.4 0.6 1.1 0.4 1.0 0.1 3.4 0.3 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP2F1 CYP2F ENSG00000197446 "Cytochrome P450 family 2 subfamily F member 1" P24903 19 41114432-41128381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.4;salivary gland: 1.0;testis: 2.1" "Cell type enriched" "Detected in some" 4 "Club cells: 67.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "HMC-1: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.04e-1)" "unprognostic (8.79e-2)" "unprognostic (4.63e-1)" "unprognostic (4.60e-2)" "unprognostic (2.54e-1)" "unprognostic (7.29e-3)" "unprognostic (6.23e-3)" "unprognostic (2.87e-2)" "unprognostic (3.91e-2)" "unprognostic (1.58e-6)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (1.50e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.5 0.0 67.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 16.5 0.0 0.0 0.0 1.6 8.0 5.3 1.5 0.0 0.0 0.6 0.0 0.0 0.1 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 44.7 0.1 0.1 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.8 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.2 0.0 0.0 3.9 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 6.4 0.1 1.7 1.9 0.0 0.0 0.6 1.9 3.3 0.0 0.2 0.0 1.0 0.0 0.2 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.7 0.1 2.4 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.2 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 304.9" "Group enriched" "Detected in some" 17 "Cholangiocytes: 85.8;Hepatocytes: 60.5" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.3;Hep G2: 2.5;HHSteC: 1.4" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" 0.2 0.9 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.2 0.5 0.3 0.3 0.1 0.0 6.5 0.0 0.0 0.1 8.5 304.9 2.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.1 85.8 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.3 60.5 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.8 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 1.3 0.0 0.2 CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.7" "Group enriched" "Detected in some" 10 "Cholangiocytes: 4.3;Hepatocytes: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 1.1 0.1 0.0 0.0 1.5 12.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.9;liver: 72.3" "Cell type enhanced" "Detected in many" "Ductal cells: 15.6;Hepatocytes: 62.9;Prostatic glandular cells: 36.3;Urothelial cells: 26.1" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.1;CAPAN-2: 50.4;EFO-21: 18.5;Hep G2: 25.0;RPMI-8226: 13.5;RT4: 15.2" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" 0.3 2.9 5.2 0.6 5.3 0.6 2.1 5.1 5.3 1.6 0.0 3.5 10.7 0.5 16.4 13.0 3.0 18.7 0.2 4.3 5.5 6.4 72.3 0.6 0.4 9.3 9.6 0.1 5.1 0.1 0.5 0.1 6.3 3.8 2.6 1.6 3.8 4.3 0.5 1.0 23.9 0.1 4.8 1.0 4.1 1.1 6.6 0.0 3.0 0.0 0.9 5.7 3.4 5.0 13.1 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 50.4 0.1 18.5 0.0 10.5 1.5 0.0 6.6 0.0 0.0 0.1 0.1 4.2 25.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 10.0 0.0 1.9 0.1 0.3 0.1 11.4 0.0 0.1 0.1 13.5 3.4 15.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.6 0.2 0.4 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.3 5.1 5.3 4.3 5.5 9.3 9.6 6.3 4.8 6.6 5.0 0.1 0.0 0.0 9.1 0.2 0.1 7.7 5.3 0.0 0.0 1.4 1.7 0.4 10.0 4.4 9.2 0.0 0.0 0.0 6.9 1.9 15.6 0.0 2.8 0.6 0.3 1.2 2.7 0.0 11.5 0.0 0.3 0.0 4.4 0.0 0.3 0.4 62.9 0.0 0.0 0.0 2.0 2.0 2.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 3.0 0.0 0.0 0.8 9.2 3.2 0.0 0.0 36.3 11.7 8.3 7.6 0.1 0.0 0.6 0.6 0.0 0.0 0.5 0.3 0.0 0.1 0.1 2.7 26.1 CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" 3.2 1.1 0.6 1.2 0.9 0.9 2.7 0.6 1.5 6.0 0.4 15.1 39.1 1.5 0.5 18.1 3.2 2.4 1.5 0.9 2.4 1.8 40.1 1.2 0.5 0.9 1.1 1.6 0.3 0.0 0.5 0.5 1.1 5.0 7.8 0.1 4.3 1.0 0.6 21.1 41.5 1.9 0.7 1.0 12.0 0.2 0.7 0.8 0.9 0.9 2.6 10.5 11.2 1.9 0.0 4.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.6 0.5 0.0 0.0 0.3 32.0 0.0 0.0 0.0 2.0 0.0 0.0 1.7 9.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.1 0.0 46.3 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.1 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.1 0.0 14.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.6 1.5 0.9 2.4 0.9 1.1 1.1 0.7 0.7 1.9 6.3 0.0 1.8 2.6 0.5 14.0 10.0 8.3 13.1 0.0 0.5 0.3 1.0 5.7 7.1 0.0 0.0 0.1 0.0 58.8 0.0 0.6 1.6 0.2 0.1 3.0 7.8 8.0 0.2 0.0 0.1 3.8 57.6 0.3 0.0 0.0 1.4 30.3 0.4 0.0 0.2 24.8 2.0 0.9 1.6 3.2 4.1 0.3 1.8 0.0 0.0 2.7 0.0 0.0 0.4 1.9 51.9 1.2 0.2 3.5 125.3 2.2 4.9 0.1 0.0 0.3 2.5 0.4 0.1 20.5 21.2 0.3 0.5 0.1 29.6 24.8 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "seminal vesicle: 215.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.1" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.2 215.6 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.4 1.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 1.7 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 2.5 CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 15.2;SK-MEL-30: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" 7.4 16.4 5.1 5.2 6.8 2.1 5.7 5.6 5.0 8.6 17.9 9.6 16.5 5.6 2.6 5.0 6.1 14.7 9.2 4.8 5.1 33.9 113.5 10.8 5.6 5.3 6.0 5.7 15.6 33.4 3.7 3.5 5.3 8.2 11.9 14.2 7.0 7.5 4.5 1.3 16.7 7.1 5.4 11.2 6.2 3.2 5.6 6.5 17.3 5.0 4.9 6.4 2.3 6.3 3.4 1.8 0.8 0.0 15.2 6.3 0.2 4.4 9.9 1.7 1.9 0.0 13.0 1.1 0.5 3.5 5.9 1.6 1.9 1.7 0.3 6.0 2.2 4.7 0.8 0.5 5.6 2.6 1.9 5.8 0.8 1.9 1.0 5.9 0.1 6.4 1.4 14.3 6.8 2.9 3.6 1.3 1.5 1.6 0.0 3.1 0.7 1.0 7.4 6.1 4.0 4.9 1.1 0.0 27.5 0.3 2.6 4.6 4.1 3.6 0.7 3.5 1.6 0.1 0.0 0.5 10.9 11.0 4.7 0.0 0.6 0.0 1.8 1.9 1.0 0.4 1.4 1.8 0.7 1.0 1.3 1.3 0.0 0.8 3.1 1.3 1.1 0.9 5.1 6.8 5.6 5.0 4.8 5.1 5.3 6.0 5.3 5.4 5.6 6.3 9.0 6.4 11.5 31.3 13.8 2.5 4.5 5.1 9.6 33.6 9.3 7.2 18.8 42.9 8.7 14.7 31.3 2.0 9.6 14.7 9.8 24.2 2.7 6.7 5.1 7.7 16.9 16.4 15.4 22.4 2.1 14.2 12.8 7.6 7.0 6.5 8.9 103.7 13.5 5.0 23.4 16.5 2.0 14.8 6.0 2.1 5.0 11.3 3.6 6.5 3.5 52.2 4.1 15.6 11.0 9.6 9.0 6.4 12.3 3.8 47.2 28.5 11.9 27.4 0.0 10.1 10.6 8.9 6.3 6.8 3.1 1.0 17.2 6.7 10.5 5.7 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.5;Club cells: 59.0;Excitatory neurons: 37.4;Respiratory ciliated cells: 104.6" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.6;CACO-2: 4.6;NTERA-2: 2.1;SCLC-21H: 2.7;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 11.6 3.2 8.2 0.7 8.5 0.1 14.9 5.2 10.2 37.1 2.8 1.6 1.7 2.1 2.7 14.7 9.3 1.6 8.6 8.7 12.1 5.9 10.5 8.8 1.9 4.5 5.6 1.2 1.7 1.7 3.8 1.1 5.7 8.0 1.9 2.3 31.1 2.9 4.6 7.1 1.4 1.9 4.1 0.6 22.3 4.0 9.2 1.1 5.0 4.0 9.1 3.3 7.2 6.4 0.0 0.0 0.0 0.0 2.6 0.2 0.1 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.3 0.0 0.4 0.2 2.7 0.0 0.0 0.2 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 8.5 5.2 10.2 8.7 12.1 4.5 5.6 5.7 4.1 9.2 6.4 4.4 22.4 17.0 2.3 0.0 2.5 26.9 37.5 25.0 2.4 31.0 0.9 0.8 1.5 59.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 8.4 7.6 0.8 4.0 0.0 0.0 37.4 0.7 0.0 7.1 4.1 1.4 0.0 0.0 1.1 2.8 3.9 0.0 29.3 0.2 18.3 0.6 0.7 8.6 10.5 0.5 5.4 4.7 0.0 0.1 0.0 1.0 2.0 0.1 0.0 20.7 0.0 8.4 0.5 1.7 104.6 0.8 0.0 2.0 19.1 0.5 3.6 21.4 1.4 0.1 0.5 0.1 1.9 31.8 CYP4Z1 CYP4A20 ENSG00000186160 "Cytochrome P450 family 4 subfamily Z member 1" Q86W10 1 47067231-47118318 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 6.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Breast glandular cells: 8.3;Early spermatids: 2.5;Excitatory neurons: 8.3;Inhibitory neurons: 5.8" "Cancer enriched" "Detected in some" 50 "breast cancer: 42.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HDLM-2: 8.1;SK-BR-3: 3.2" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.11e-2)" "unprognostic (2.57e-2)" "unprognostic (2.46e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (4.33e-4)" "unprognostic (1.10e-1)" "unprognostic (3.53e-3)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (3.53e-1)" "unprognostic (6.82e-3)" "unprognostic (5.09e-3)" "unprognostic (3.88e-2)" "unprognostic (6.46e-2)" "unprognostic (3.49e-3)" 2.2 0.2 0.9 0.0 0.9 0.0 6.3 0.2 1.1 0.3 0.0 0.2 0.0 0.3 0.3 0.7 0.6 0.0 0.8 0.8 1.3 0.2 0.7 1.6 0.0 0.4 0.4 0.0 0.1 0.0 0.6 0.0 0.3 1.2 0.0 0.0 0.8 0.3 0.7 1.0 0.2 0.0 0.2 0.0 0.4 0.4 1.1 0.2 0.5 0.2 0.2 0.4 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.2 1.1 0.8 1.3 0.4 0.4 0.3 0.2 1.1 0.9 0.3 9.6 1.1 1.0 0.0 0.1 0.5 0.4 0.0 0.0 8.3 0.4 0.4 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.5 0.2 0.1 0.9 0.0 0.0 8.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.7;Oligodendrocyte precursor cells: 94.5;Oligodendrocytes: 119.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Group enriched" "Detected in some" 4 "HSkMC: 16.5;SH-SY5Y: 5.5;WM-115: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" 8.4 5.4 5.7 5.6 11.4 0.3 6.3 8.2 6.6 5.7 8.6 2.3 1.8 2.8 2.0 7.3 2.7 5.8 3.6 5.3 6.8 7.9 21.5 4.6 2.4 11.8 7.3 4.2 6.7 11.4 0.8 0.5 11.4 4.4 3.5 1.9 4.6 5.6 0.2 5.9 1.8 4.3 8.4 9.2 2.4 1.7 8.1 2.1 12.2 1.7 2.9 7.9 3.0 27.2 1.5 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 5.5 0.0 0.0 2.2 0.8 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.7 11.4 8.2 6.6 5.3 6.8 11.8 7.3 11.4 8.4 8.1 27.2 3.3 0.0 3.4 93.7 0.1 10.6 6.6 1.0 7.4 4.9 4.2 5.5 3.0 2.8 0.9 7.3 2.1 0.1 0.4 0.0 3.9 4.4 7.4 0.2 6.9 2.1 1.8 1.3 29.3 4.9 0.2 15.9 0.5 0.1 12.7 0.6 2.5 8.2 0.2 3.3 30.6 0.5 0.0 0.3 4.9 8.6 5.9 0.5 17.8 30.0 1.0 6.9 0.0 94.5 119.2 1.2 0.0 4.9 0.0 4.2 0.0 2.9 0.8 0.5 13.1 1.1 16.8 4.1 3.4 6.2 12.6 0.0 1.3 7.6 0.0 3.1 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734949 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 968.3" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 646.2" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 5.6" "Lineage enriched" "Detected in single" 17 "T-cells: 5.6" "Cell line enriched" "Detected in some" 5 "ASC diff: 989.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced NA NA 110000 "Cluster 35: T-regs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA047729: AB_2680135" "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" 22.4 7.7 9.8 14.6 15.4 0.3 12.0 23.0 22.0 2.8 8.1 4.2 1.2 4.2 15.7 2.1 5.1 8.0 7.5 11.0 16.0 24.3 968.3 39.9 4.3 14.3 21.4 59.9 3.2 0.2 8.8 72.5 16.3 27.8 3.3 0.6 2.5 13.0 5.5 33.8 5.0 12.9 9.4 7.3 7.1 7.2 12.8 0.6 5.2 10.6 1.9 27.9 6.3 17.5 0.4 0.0 0.0 0.0 989.2 102.8 0.0 0.1 36.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 206.6 0.2 0.1 5.4 0.0 6.9 0.4 0.9 0.0 0.0 0.0 51.2 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 16.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 34.9 8.4 4.0 0.2 0.2 0.3 1.4 0.3 0.3 5.7 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 5.6 1.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 1.7 0.4 9.8 15.4 23.0 22.0 11.0 16.0 14.3 21.4 16.3 9.4 12.8 17.5 0.4 3.2 0.0 1.3 0.8 0.1 0.4 4.8 0.6 0.5 0.2 0.0 1.4 30.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.9 0.6 1.0 0.0 5.3 3.3 0.0 0.1 66.4 0.5 2.8 0.0 0.0 7.5 646.2 8.3 0.0 2.8 0.0 0.0 7.9 2.3 2.8 29.2 3.7 0.0 28.1 0.6 16.2 0.0 0.5 55.7 0.4 0.0 7.9 0.0 0.9 0.0 0.2 0.1 0.5 0.0 2.6 5.5 0.0 0.2 0.1 0.1 0.3 1.1 0.3 0.0 1.7 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 191.3;Distal enterocytes: 476.1;Intestinal goblet cells: 288.8;Paneth cells: 226.2;Proximal enterocytes: 270.2;Syncytiotrophoblasts: 114.5;Undifferentiated cells: 170.9" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 11.4;OE19: 29.0;RPMI-8226: 13.9;RT4: 13.9;SCLC-21H: 14.9;SK-BR-3: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 2.1 5.4 1.6 13.4 4.6 0.1 14.0 2.8 2.8 15.5 0.7 249.9 40.0 11.8 4.0 10.9 10.4 6.8 1.9 1.6 1.3 335.2 5.5 3.2 1.0 2.7 1.3 9.3 7.4 3.6 0.5 13.0 3.3 12.9 102.2 0.0 260.2 6.2 0.9 66.1 141.8 18.3 1.5 7.0 9.8 2.5 2.0 0.4 11.1 0.2 0.9 5.3 23.6 2.4 3.6 1.1 0.4 1.4 0.1 1.7 3.6 0.0 0.0 0.1 0.1 6.1 1.3 0.0 2.7 0.1 0.1 7.8 5.1 0.5 0.0 0.0 1.8 0.0 0.7 6.6 0.6 0.7 0.0 1.7 3.0 0.3 0.1 0.0 0.0 4.6 0.4 0.0 0.0 3.8 0.2 0.2 11.4 29.0 1.0 0.0 0.2 13.9 0.5 13.9 14.9 1.0 0.8 13.4 0.6 1.3 6.5 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.6 2.8 2.8 1.6 1.3 2.7 1.3 3.3 1.5 2.0 2.4 0.7 0.0 0.5 0.0 1.1 1.5 7.2 1.3 1.2 0.0 4.8 2.2 0.5 30.0 2.3 191.3 0.0 1.2 0.3 476.1 45.0 2.1 0.2 17.4 25.2 0.5 26.9 0.0 1.1 3.0 0.7 7.1 7.1 43.5 8.9 43.4 1.1 1.2 1.4 0.0 0.8 288.8 4.1 0.3 0.5 0.5 25.4 0.7 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.6 226.2 6.8 0.2 13.5 270.2 16.3 0.4 0.0 13.1 0.3 3.9 0.2 1.6 3.5 3.4 114.5 1.2 16.7 170.9 10.5 HSD17B1 "EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1" ENSG00000108786 "Hydroxysteroid 17-beta dehydrogenase 1" P14061 17 42552922-42555214 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 82.3" "Group enriched" "Detected in many" 4 "Granulosa cells: 1574.2;Syncytiotrophoblasts: 1495.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 8 "BEWO: 399.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021032, HPA065296" Enhanced Supported Cytosol NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA021032: AB_1844345, HPA065296: AB_2685457" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (1.68e-2)" "unprognostic (9.25e-2)" "unprognostic (1.73e-1)" "unprognostic (3.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (9.35e-2)" "unprognostic (6.04e-2)" "unprognostic (2.88e-5)" "unprognostic (2.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.60e-2)" "unprognostic (5.09e-1)" "unprognostic (4.98e-1)" "unprognostic (1.32e-2)" 4.4 1.9 3.8 1.7 4.2 0.8 3.0 3.9 4.6 3.0 2.7 2.2 2.1 2.1 0.7 6.0 3.2 0.5 2.1 3.8 3.5 2.4 2.0 1.5 1.0 4.8 3.5 6.8 3.0 0.6 2.4 82.3 4.4 2.6 0.1 0.6 3.7 0.5 4.4 6.3 2.1 0.2 3.2 2.0 2.2 3.8 3.9 0.4 2.8 0.0 0.4 1.7 3.1 6.1 7.0 6.0 1.8 20.2 1.0 0.3 399.0 4.3 0.0 0.0 0.0 2.9 2.8 0.1 4.0 0.2 1.8 9.7 0.7 3.9 0.0 7.6 10.7 3.7 3.8 4.3 0.9 2.7 3.9 0.9 13.2 0.5 2.7 1.5 0.1 2.6 5.7 1.2 0.0 4.8 3.2 2.3 0.4 1.4 2.8 3.9 3.0 2.5 0.5 3.4 4.3 5.6 2.4 41.4 4.2 0.9 48.5 1.1 4.3 2.7 5.4 2.4 2.7 7.7 4.6 1.5 1.9 1.9 2.8 1.0 2.2 2.5 1.1 2.4 1.3 1.2 1.4 1.1 1.3 1.4 1.0 1.0 2.2 1.6 1.5 0.9 0.8 2.0 3.8 4.2 3.9 4.6 3.8 3.5 4.8 3.5 4.4 3.2 3.9 6.1 2.3 0.0 2.2 6.5 2.2 3.1 8.0 14.9 6.2 8.3 11.6 10.7 3.0 4.3 5.3 5.5 12.5 333.0 3.3 4.7 23.5 1.7 1.4 3.3 9.3 4.2 4.2 0.8 1.4 5.6 30.4 11.6 1.5 3.8 2.5 1574.2 3.6 6.4 29.7 10.1 1.6 2.7 8.2 0.6 1.2 1.9 1.8 3.6 1.8 1.9 1.0 11.2 2.1 2.0 3.3 2.0 2.0 3.4 1.4 11.6 2.5 20.5 4.2 8.9 0.0 6.7 29.2 0.8 2.7 14.6 7.4 1495.8 2.6 30.0 2.6 10.4 HSD17B10 "17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1" ENSG00000072506 "Hydroxysteroid 17-beta dehydrogenase 10" Q99714 X 53431258-53434370 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, tRNA processing" Oxidoreductase "Disease variant, FDA approved drug targets, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 444.0;Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001432 Approved NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA001432: AB_1078740" "unprognostic (1.27e-1)" "prognostic favorable (2.80e-4)" "unprognostic (2.60e-1)" "unprognostic (2.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-1)" "unprognostic (8.64e-3)" "unprognostic (4.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.95e-2)" "unprognostic (8.38e-2)" "unprognostic (3.07e-3)" "unprognostic (2.92e-1)" "unprognostic (9.51e-2)" 71.1 110.7 63.5 52.5 67.5 64.8 62.7 70.0 64.7 58.1 64.6 62.8 58.0 62.0 56.2 111.6 55.4 33.4 103.8 62.0 68.4 99.1 261.3 48.4 59.4 70.4 68.2 67.1 74.8 73.4 66.1 37.2 67.8 50.7 62.9 12.7 55.0 46.0 90.5 90.0 50.3 62.0 66.6 52.0 66.4 21.5 69.1 60.1 66.4 81.6 76.3 56.3 59.8 69.2 121.9 203.1 97.2 181.3 93.4 41.0 146.5 73.7 72.9 192.0 125.3 210.3 101.8 205.8 65.6 84.9 124.2 124.5 316.1 148.7 104.3 164.1 177.7 97.1 283.6 177.0 156.3 185.1 145.5 87.6 138.9 148.7 82.8 41.6 142.2 181.2 141.6 158.1 90.3 426.7 165.3 277.0 269.9 163.0 259.5 166.2 179.2 364.9 149.3 132.2 171.1 225.1 211.7 250.2 138.6 123.0 263.3 169.8 64.2 81.7 129.7 171.9 113.4 128.3 194.1 256.5 113.4 384.9 123.2 54.2 127.8 40.4 84.8 125.1 87.2 98.8 78.0 84.1 176.7 111.4 64.4 67.9 10.5 98.7 94.5 96.5 114.8 126.6 63.5 67.5 70.0 64.7 62.0 68.4 70.4 68.2 67.8 66.6 69.1 69.2 42.8 48.1 37.3 4.9 61.8 86.4 90.2 150.8 44.9 11.8 72.5 74.9 62.0 107.2 70.2 101.2 4.2 173.2 55.0 73.8 283.7 131.5 1.6 26.1 64.7 58.3 104.6 71.3 2.5 135.4 228.1 72.0 28.1 51.9 56.5 75.3 56.4 444.0 136.8 13.5 3.3 78.2 99.7 73.9 98.6 5.7 78.3 65.4 96.0 3.7 118.7 61.3 89.6 6.6 6.2 101.9 54.1 94.8 83.3 74.6 78.5 427.8 31.5 13.2 78.9 63.1 117.9 23.6 56.3 91.3 116.2 151.6 62.4 104.1 103.0 83.7 HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 288.6;liver: 241.6" "Cell type enhanced" "Detected in all" "Paneth cells: 498.6;Proximal enterocytes: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 768.7" "Group enriched" "Detected in all" 4 "granulocytes: 768.7;monocytes: 202.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 295.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" 56.0 64.1 15.0 33.0 15.7 109.9 45.5 19.7 18.6 44.0 18.8 139.6 216.7 57.5 28.2 21.5 44.2 107.7 21.0 15.6 18.4 75.9 241.6 104.4 41.5 20.1 17.5 60.6 54.5 10.9 13.1 47.2 18.9 25.5 145.8 8.2 14.8 34.2 12.1 14.5 288.6 49.4 19.3 42.7 36.6 10.1 16.7 36.3 19.3 26.3 34.9 41.8 33.5 22.8 1.0 45.4 22.2 56.1 66.5 92.4 31.2 23.4 39.3 16.1 29.9 38.2 295.2 0.0 45.8 26.2 14.8 0.9 65.6 5.2 18.0 72.1 13.8 63.3 22.9 131.0 37.6 114.8 114.0 65.3 1.7 22.5 7.4 51.3 31.5 27.4 67.9 32.7 30.1 1.8 24.0 144.8 37.8 146.7 7.6 63.2 20.4 77.7 45.5 70.0 7.2 69.3 47.5 1.6 87.0 28.2 0.1 112.7 24.9 11.0 47.9 43.1 13.0 15.0 6.6 7.1 20.1 80.6 77.0 591.1 202.0 442.9 62.5 142.7 74.8 57.1 62.6 64.6 108.2 47.6 55.8 64.2 768.7 82.3 125.8 36.8 77.4 171.6 15.0 15.7 19.7 18.6 15.6 18.4 20.1 17.5 18.9 19.3 16.7 22.8 169.0 314.1 179.5 13.4 89.0 28.0 77.0 16.0 10.8 1.8 5.0 6.2 5.3 368.9 83.7 44.1 2.1 30.6 63.1 356.8 25.4 53.9 1.2 9.0 28.1 101.8 93.7 68.8 16.8 58.6 59.7 77.3 28.1 18.8 100.1 34.1 112.5 337.3 129.1 18.5 14.7 180.8 18.3 220.4 176.2 5.1 104.1 139.1 67.6 43.1 197.3 36.3 113.3 16.6 19.0 65.9 498.6 59.5 60.8 39.5 1134.9 173.6 62.2 3.9 72.3 77.9 43.0 2.7 15.4 10.4 21.5 14.9 93.8 65.4 281.0 93.9 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 60.9 65.4 42.0 31.4 50.4 25.1 48.8 58.1 63.0 51.3 71.5 65.8 67.3 37.4 50.6 36.3 41.3 35.6 69.5 42.0 54.3 91.3 122.9 51.4 28.5 58.8 52.1 45.3 43.5 134.3 28.5 41.6 58.9 52.8 59.5 47.0 46.9 41.5 27.8 30.0 41.7 48.6 52.8 34.8 56.1 33.5 48.9 22.3 66.8 51.6 32.3 31.4 26.8 61.9 40.2 64.3 68.4 69.6 226.8 211.5 45.0 96.7 97.8 67.3 73.0 75.7 80.7 97.4 69.4 91.5 111.7 151.6 48.7 125.5 82.6 19.0 89.2 46.4 28.3 66.2 114.6 132.3 125.4 131.1 93.6 68.1 193.6 85.9 96.1 60.4 43.9 157.9 59.4 22.9 38.6 63.1 126.0 49.9 45.3 63.9 102.3 110.8 129.5 95.9 24.5 56.5 132.0 110.7 100.2 64.6 80.2 112.5 92.4 73.9 28.3 189.3 117.6 81.6 110.3 58.3 78.5 25.0 55.4 8.8 13.4 7.0 12.1 14.8 13.5 12.7 9.6 10.5 21.3 15.2 15.6 13.9 11.2 16.4 8.2 18.4 6.2 11.6 42.0 50.4 58.1 63.0 42.0 54.3 58.8 52.1 58.9 52.8 48.9 61.9 73.6 64.1 111.1 96.6 45.4 31.7 47.1 92.8 57.5 77.1 46.1 36.4 80.7 74.4 81.4 51.5 77.2 60.4 30.6 82.2 27.4 100.2 61.8 36.9 47.5 70.9 138.2 40.8 126.9 82.3 42.1 59.7 60.6 37.0 155.9 37.3 76.1 214.0 63.5 121.1 155.6 75.5 87.5 50.9 43.7 24.1 34.2 45.3 39.2 59.0 37.2 128.2 30.9 128.7 97.5 71.4 62.5 56.8 61.4 61.3 54.2 50.1 75.8 67.8 78.9 45.4 60.2 17.5 14.5 66.0 45.7 74.8 29.4 95.5 115.5 48.6 HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 429.0;liver: 217.9;placenta: 381.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 155.8;Distal enterocytes: 203.4;Hepatocytes: 121.9;Paneth cells: 284.2;Proximal enterocytes: 390.7" "Group enriched" "Detected in many" 4 "liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 57.9;Hep G2: 47.5;hTERT-HME1: 27.1;OE19: 87.1;RT4: 96.8;TIME: 54.0" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: AB_2681059" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.83e-4)" 1.6 0.0 0.4 4.2 0.2 0.7 26.4 0.9 0.4 4.3 0.2 74.8 429.0 1.2 0.1 9.6 0.1 21.1 0.2 0.3 0.2 9.6 217.9 2.3 0.3 0.1 0.0 0.3 23.2 0.0 1.2 381.8 0.1 2.0 56.9 17.4 22.1 0.2 0.1 4.2 188.6 2.4 0.0 0.2 20.1 0.3 0.1 0.4 0.1 0.0 3.4 78.6 1.4 0.3 0.4 0.1 0.4 0.0 0.0 0.7 0.7 0.2 57.9 0.0 0.0 10.9 1.7 0.1 11.4 0.0 0.1 0.4 0.0 2.4 0.0 0.1 0.1 0.3 0.3 47.5 0.4 0.3 0.3 0.0 3.1 0.0 27.1 0.6 0.9 0.1 0.1 0.4 8.6 0.1 0.0 0.9 0.2 87.1 21.4 0.1 0.2 1.3 1.0 96.8 0.4 1.5 0.0 2.7 0.2 0.0 0.1 0.1 54.0 0.6 0.5 0.3 0.0 0.2 0.2 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.9 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.3 1.0 3.2 3.9 0.3 0.7 0.4 2.7 16.4 2.2 0.5 45.7 12.3 0.6 155.8 21.4 0.0 0.0 2.7 0.3 203.4 0.0 73.6 0.5 5.9 5.4 21.3 3.0 2.7 0.1 6.0 1.8 38.3 15.3 41.3 0.0 0.0 2.5 121.9 3.5 0.0 0.1 26.3 6.1 3.1 0.0 0.9 0.0 0.4 1.8 0.0 0.0 45.1 0.0 0.0 0.1 20.1 284.2 0.0 0.1 2.7 390.7 1.4 5.6 0.7 0.0 0.4 2.0 0.0 0.1 0.8 1.1 6.4 0.7 0.0 47.1 14.8 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA047496: AB_2680068" "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" 4.3 16.1 3.3 5.1 3.1 2.8 8.2 3.0 6.0 5.6 3.8 6.4 6.7 4.0 7.2 8.9 5.1 4.2 3.5 2.9 4.0 5.2 30.2 7.6 8.3 3.8 3.7 6.8 5.3 5.1 7.7 4.6 3.9 5.9 8.0 4.0 6.2 3.5 6.0 7.6 6.6 4.4 3.3 5.6 5.9 2.6 3.7 8.1 6.1 2.8 8.1 5.5 5.6 3.7 12.6 12.2 32.4 13.8 18.4 18.3 20.2 4.6 15.9 9.4 19.0 17.0 35.7 29.6 10.6 4.4 58.3 19.1 30.6 43.4 9.9 12.4 15.5 7.7 8.2 26.8 15.2 13.9 12.7 11.6 23.5 36.8 11.6 7.4 15.7 19.4 14.5 19.0 8.3 8.9 17.7 13.7 20.5 24.4 15.3 9.5 19.3 18.5 33.3 19.5 27.6 14.6 8.0 7.7 7.9 27.5 12.3 17.1 9.8 4.4 10.2 6.7 10.0 11.2 12.7 29.4 6.6 1.2 11.1 21.7 6.7 12.1 13.6 6.8 14.8 12.6 10.1 13.7 6.9 11.9 12.9 12.4 5.5 8.2 8.5 10.0 17.9 12.2 3.3 3.1 3.0 6.0 2.9 4.0 3.8 3.7 3.9 3.3 3.7 3.7 8.8 0.0 25.5 22.5 22.6 11.0 19.5 48.3 35.9 23.6 24.9 11.9 2.4 12.8 26.1 11.0 62.6 17.2 19.9 14.9 3.9 16.9 2.0 9.4 7.9 12.0 6.0 4.2 8.4 27.1 15.1 13.1 8.6 9.3 5.1 32.8 8.9 62.0 13.4 11.8 9.1 14.5 18.3 5.0 16.9 1.9 6.8 12.2 17.8 5.6 10.6 14.3 16.5 12.5 22.6 15.0 17.9 7.2 18.1 19.0 12.1 10.2 19.9 44.1 0.0 5.9 10.5 4.9 6.6 15.6 12.6 19.2 23.5 34.1 11.6 12.6 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 5 "Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 23.5 0.0 20.4 0.0 0.0 0.0 0.0 0.3 60.8 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.1 0.0 18.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 1.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.7 29.6 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.5 0.0 0.0 0.4 20.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 59.9 0.6 0.1 0.0 3.7 0.0 0.0 0.0 0.5 0.9 0.1 0.0 1.2 0.0 0.7 0.0 0.3 7.3 0.0 0.0 0.0 0.2 1.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 8.6 SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 79.6" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favorable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" 12.5 12.0 10.4 2.5 11.5 3.7 12.2 11.0 12.4 12.9 9.2 7.3 3.8 6.8 4.2 26.1 5.6 10.3 9.3 10.7 10.1 9.6 14.5 10.5 2.5 11.0 11.2 3.1 20.2 7.0 5.9 4.0 10.8 7.4 4.1 1.5 16.4 2.9 6.3 15.4 7.0 2.6 10.9 6.8 9.7 3.3 10.9 6.0 7.6 5.4 6.0 10.0 14.7 12.7 9.7 4.3 10.3 10.1 29.4 20.4 5.6 10.4 9.3 2.4 5.4 6.5 19.5 21.2 11.7 11.0 11.1 7.0 5.3 7.9 3.9 6.6 17.1 12.3 5.2 15.8 9.2 23.7 6.1 17.6 14.5 5.4 5.3 7.8 14.4 38.5 21.2 47.7 21.1 10.8 36.0 10.3 13.0 53.2 9.3 11.4 3.3 14.0 12.8 7.9 16.0 9.1 10.7 79.6 8.3 9.0 9.4 17.9 8.3 25.0 4.7 2.0 8.1 28.6 15.8 7.9 34.1 29.5 25.9 25.6 35.8 11.7 16.1 56.5 18.6 12.5 12.0 15.2 30.2 12.7 10.2 14.4 1.8 8.6 59.5 61.7 12.5 23.1 10.4 11.5 11.0 12.4 10.7 10.1 11.0 11.2 10.8 10.9 10.9 12.7 25.4 9.6 15.9 4.6 7.8 13.6 13.3 245.5 5.2 4.9 43.8 29.3 5.3 34.3 245.2 5.5 4.2 27.0 21.2 12.2 3.9 93.4 3.2 51.2 31.0 19.6 12.0 14.9 11.1 105.4 106.0 16.2 13.3 105.9 14.0 6.7 17.5 18.6 63.4 10.1 17.1 22.6 57.0 32.4 34.1 0.5 1.8 27.6 24.9 4.7 31.3 21.9 18.6 8.5 23.4 155.5 10.0 5.7 16.8 17.5 9.4 18.4 195.0 3.9 13.1 13.3 28.2 3.5 20.1 32.7 29.7 7.5 7.2 15.4 23.3 108.6 STAR STARD1 ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38142700-38150992 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "adrenal gland: 5073.8" "Cell type enriched" "Detected in some" 44 "Theca cells: 2243.4" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.0;lung cancer: 0.8;ovarian cancer: 1.4;testis cancer: 3.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.4" "Cell line enriched" "Detected in some" 5 "K-562: 436.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "CAB032598: AB_2115937, HPA023644: AB_10598916, HPA027318: AB_10601574" "unprognostic (1.60e-4)" "unprognostic (3.20e-2)" "unprognostic (9.17e-2)" "unprognostic (3.28e-2)" "unprognostic (9.22e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.12e-5)" "unprognostic (3.30e-2)" "unprognostic (2.36e-1)" "unprognostic (1.77e-3)" "unprognostic (6.65e-2)" "unprognostic (4.75e-9)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.16e-2)" 1.7 5073.8 2.3 3.1 1.6 2.1 0.4 1.6 3.3 1.0 0.7 0.5 0.2 0.5 0.6 2.1 6.3 0.2 0.9 1.5 4.5 0.4 1.2 0.5 0.9 3.8 3.3 497.1 0.9 0.0 2.2 0.5 4.1 0.5 0.1 0.6 1.8 0.3 0.4 5.0 0.6 0.4 1.4 1.0 0.7 88.2 3.0 3.0 0.4 0.0 1.9 0.5 3.2 1.5 0.1 0.0 0.8 0.2 0.3 3.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 88.9 0.8 5.3 1.3 3.8 0.1 12.4 0.3 0.1 0.1 0.8 0.0 0.3 436.1 0.2 0.0 0.0 0.4 43.7 9.6 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.2 0.2 0.0 0.2 0.0 0.1 43.0 1.5 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 9.3 0.2 2.4 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.0 2.3 1.6 1.6 3.3 1.5 4.5 3.8 3.3 4.1 1.4 3.0 1.5 0.0 0.0 0.0 0.7 0.1 9.4 0.7 0.8 4.0 1.1 0.1 1.1 0.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.9 10.7 0.6 0.0 0.0 1.4 0.0 0.0 25.7 0.0 0.3 0.0 1.4 0.0 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.7 10.2 50.1 0.2 3.6 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.0 4.1 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.2 3.0 4.8 0.8 1.7 11.2 0.1 0.1 2243.4 0.0 0.1 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 212.5;Excitatory neurons: 120.7;Inhibitory neurons: 135.6;Microglial cells: 167.7;Oligodendrocyte precursor cells: 212.6;Oligodendrocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 50.2;TIME: 36.0;WM-115: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039535: AB_10965929, HPA058867: AB_2683839" "unprognostic (7.42e-2)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (3.42e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-2)" 16.0 10.9 10.0 5.6 13.2 0.3 11.1 8.7 10.9 16.6 13.4 28.0 4.8 14.8 5.3 7.2 10.4 10.8 12.5 12.6 8.1 8.4 6.1 12.5 2.5 11.1 11.9 7.2 10.8 16.9 4.3 24.6 9.6 9.0 6.8 1.8 6.4 8.1 5.4 5.3 7.0 15.7 8.4 7.4 11.2 2.8 11.7 1.4 20.4 6.3 1.4 14.0 9.6 13.6 11.4 1.6 3.4 2.4 6.8 16.0 0.6 21.2 26.2 17.4 10.8 0.9 4.0 0.1 2.8 10.2 10.7 10.4 1.5 7.5 22.0 10.0 3.6 5.2 3.9 5.2 5.7 0.0 4.6 13.3 4.3 19.7 24.0 9.7 17.1 0.1 0.0 1.7 50.2 3.3 0.0 0.0 2.2 1.2 5.7 0.2 16.6 0.1 10.6 3.2 0.1 5.5 3.2 8.0 2.6 3.0 18.5 4.7 36.0 8.7 9.3 22.0 11.0 2.9 0.0 0.1 7.0 0.1 40.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 10.0 13.2 8.7 10.9 12.6 8.1 11.1 11.9 9.6 8.4 11.7 13.6 30.5 28.9 15.1 212.5 0.1 2.4 2.8 1.1 4.0 5.3 8.6 5.1 19.8 7.2 2.0 9.2 0.0 9.4 4.2 11.8 0.0 7.7 1.2 5.5 26.6 18.4 6.7 0.0 120.7 2.2 3.7 18.8 10.7 6.4 5.1 6.2 17.9 10.7 16.7 5.0 135.6 4.4 0.0 8.8 6.8 1.4 7.2 10.8 14.2 167.7 0.8 1.1 0.0 212.6 470.9 5.5 4.3 7.5 4.7 4.4 3.4 2.1 6.3 0.4 13.1 15.6 33.1 0.1 0.3 1.0 2.3 7.5 0.6 31.1 5.4 1.5 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 28.0;Plasma cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;RPMI-8226: 6.2;U-266/70: 7.1;U-937: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" 1.0 0.6 0.6 6.0 0.8 4.3 0.7 3.4 1.3 7.2 1.9 2.8 2.2 4.6 5.0 3.4 1.8 1.3 0.8 0.6 0.7 0.7 5.1 1.1 7.7 0.9 1.0 1.2 0.6 0.6 0.4 1.6 1.2 3.6 3.7 0.4 1.6 2.1 0.6 7.9 4.2 1.8 0.9 6.2 2.1 0.7 0.7 0.5 0.8 0.3 1.5 2.5 5.5 1.4 0.3 0.0 0.0 0.9 2.3 2.3 0.1 0.3 0.3 0.8 1.2 0.1 0.1 4.8 0.0 1.5 0.2 4.0 1.1 1.0 0.6 0.1 0.4 1.8 0.3 0.4 0.5 2.8 5.8 2.0 2.0 0.3 0.6 1.5 0.1 1.9 0.6 1.3 0.5 0.1 0.5 4.0 0.3 0.2 0.0 0.1 0.7 6.2 0.3 1.4 0.3 0.1 0.1 0.5 0.6 0.3 0.6 0.6 0.2 1.3 0.6 1.3 0.1 7.1 1.5 1.8 0.9 6.8 0.4 5.0 1.8 2.3 3.0 2.4 2.5 1.0 2.7 3.2 2.6 0.7 3.9 3.9 1.3 2.6 2.3 1.4 3.6 3.7 0.6 0.8 3.4 1.3 0.6 0.7 0.9 1.0 1.2 0.9 0.7 1.4 3.8 0.0 1.1 0.0 11.4 13.3 12.0 28.0 10.8 1.8 2.7 4.2 0.3 0.0 4.9 0.0 6.2 2.5 4.2 22.1 3.9 1.3 15.2 2.5 14.4 2.5 11.4 2.5 2.2 1.4 4.0 8.5 15.8 2.3 10.2 1.0 3.6 25.4 5.2 1.7 2.0 24.3 2.0 7.9 10.9 1.5 5.0 8.0 1.8 1.9 0.7 1.2 2.1 0.0 0.4 1.8 14.4 9.8 31.5 3.3 23.9 0.7 4.0 0.9 0.0 3.8 2.8 0.9 0.7 19.6 16.3 4.9 4.2 6.3 19.9 9.6 STARD6 ENSG00000174448 "StAR related lipid transfer domain containing 6" P59095 18 54324358-54357964 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 26.6" "Group enriched" "Detected in some" 53 "Early spermatids: 189.8;Late spermatids: 271.2;Spermatocytes: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.0;Karpas-707: 2.7;U-266/70: 3.2;U-266/84: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (7.81e-2)" "unprognostic (1.50e-1)" "unprognostic (5.56e-3)" "unprognostic (1.70e-1)" "unprognostic (3.25e-1)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (8.98e-3)" "unprognostic (6.98e-5)" "unprognostic (1.90e-1)" "unprognostic (2.33e-3)" "unprognostic (2.68e-1)" "unprognostic (9.97e-2)" "unprognostic (1.91e-3)" "unprognostic (1.16e-3)" 0.1 0.3 0.3 0.0 0.5 0.1 0.1 0.5 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 26.6 0.6 0.3 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.3 0.2 0.1 0.0 0.4 0.1 0.0 0.7 0.1 2.0 0.3 0.1 0.0 0.0 0.2 0.7 0.3 0.5 0.1 0.2 0.1 0.2 0.3 0.7 0.1 2.7 0.3 0.0 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.7 0.3 0.7 0.7 0.4 0.0 0.1 0.2 0.0 0.2 0.7 0.2 0.5 0.3 0.2 3.2 1.6 0.3 0.9 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.5 0.5 0.6 0.4 1.1 0.4 0.3 0.5 0.1 0.6 0.7 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 189.8 0.0 0.1 0.2 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.9 0.0 0.0 0.0 0.4 271.2 2.5 0.2 0.0 0.0 0.0 1.3 0.0 2.0 1.6 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 103.9 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.1 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 STARD9 "KIAA1300, KIF16A" ENSG00000159433 "StAR related lipid transfer domain containing 9" Q9P2P6 15 42575606-42720998 "Metabolic proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;Early spermatids: 52.8;Excitatory neurons: 39.3;Oligodendrocytes: 80.9;Rod photoreceptor cells: 57.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA014562 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA014562: AB_10603033" "unprognostic (2.69e-2)" "unprognostic (2.93e-1)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (6.74e-2)" "unprognostic (5.54e-5)" "unprognostic (7.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.01e-1)" "unprognostic (1.94e-2)" "unprognostic (1.91e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-3)" "unprognostic (1.53e-2)" "unprognostic (3.92e-2)" "unprognostic (3.13e-1)" "unprognostic (1.83e-3)" 6.2 0.5 1.5 1.2 5.2 0.6 4.3 3.1 3.3 5.9 2.4 9.1 1.3 5.3 3.0 2.2 3.3 2.4 3.3 1.3 1.6 0.8 0.4 4.5 1.2 4.7 2.5 6.0 0.4 0.4 0.8 3.9 2.8 2.6 2.8 12.9 1.5 3.2 2.5 2.6 3.2 4.8 1.0 2.0 3.2 8.5 4.4 3.5 1.7 3.5 1.1 4.4 5.0 9.9 0.9 0.5 5.9 2.3 3.1 4.5 0.3 1.0 1.3 1.8 2.7 0.0 0.0 0.7 0.1 1.1 1.2 0.1 2.0 0.9 2.4 3.5 1.7 0.3 4.3 1.3 1.3 0.9 1.1 2.6 0.4 1.5 1.0 1.5 1.8 2.5 1.6 3.8 1.5 0.0 0.7 0.7 0.9 0.0 1.1 5.1 3.2 1.1 0.7 0.0 1.2 2.9 1.3 0.0 0.4 0.7 0.1 0.4 3.6 2.5 1.9 0.9 2.4 3.8 2.2 1.3 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 5.2 3.1 3.3 1.3 1.6 4.7 2.5 2.8 1.0 4.4 9.9 26.1 12.8 2.8 7.2 2.9 3.6 1.2 0.8 1.2 8.1 0.6 1.0 6.8 0.0 0.7 1.8 52.1 0.2 4.2 0.3 0.0 0.3 52.8 3.5 12.2 19.8 8.4 3.2 39.3 0.0 0.3 15.2 2.6 0.6 2.5 3.6 9.7 0.5 2.8 11.8 33.5 2.8 0.0 2.4 7.7 15.4 24.5 2.3 8.8 24.4 2.4 2.9 11.3 20.1 80.9 0.2 0.0 22.2 2.7 0.9 0.1 0.3 9.1 57.7 19.7 11.8 13.7 3.9 8.0 0.3 3.1 0.3 6.3 7.8 0.4 0.7 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7147237-7804358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.8;Excitatory neurons: 32.2;Inhibitory neurons: 39.3;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.5;RPMI-8226: 69.8;U-266/70: 110.2;U-698: 47.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 18.2 4.6 3.7 4.5 4.8 2.1 5.8 4.0 12.1 5.6 1.3 6.8 2.8 4.3 2.4 3.1 4.8 7.3 6.6 4.2 3.7 4.8 8.7 8.7 4.1 5.8 6.1 4.7 3.0 2.8 1.2 26.6 5.5 5.2 5.9 6.1 3.1 5.6 5.2 4.9 3.2 6.8 1.3 4.7 12.0 2.4 12.1 4.4 3.9 6.6 3.6 9.4 3.9 7.8 11.5 3.7 7.5 3.0 48.5 24.9 37.5 22.3 7.8 5.8 5.3 19.2 11.2 21.4 5.0 15.5 5.0 3.0 5.4 3.9 5.8 3.3 8.6 1.8 12.7 5.7 2.7 3.8 11.5 8.3 0.7 3.8 2.3 4.0 8.8 2.0 1.4 23.5 15.2 2.9 2.2 3.1 3.3 0.2 4.8 3.9 4.8 69.8 14.2 16.0 5.6 4.8 4.7 8.3 3.0 11.8 3.8 1.6 15.8 22.5 2.2 30.0 4.4 110.2 0.8 47.2 5.9 3.0 6.5 0.9 1.7 0.4 0.4 2.0 0.2 0.4 0.2 0.2 0.9 0.7 0.1 0.3 1.3 0.7 1.3 0.3 0.3 0.6 3.7 4.8 4.0 12.1 4.2 3.7 5.8 6.1 5.5 1.3 12.1 7.8 10.2 12.8 2.2 10.4 1.8 0.9 1.8 2.9 0.6 3.5 3.3 1.5 7.5 1.5 8.5 1.8 0.0 41.8 1.6 16.7 0.0 8.6 0.3 4.5 4.5 4.2 3.6 3.2 32.2 19.9 18.9 6.1 5.1 5.2 7.0 6.7 3.6 8.2 7.7 1.7 39.3 4.6 10.2 7.5 1.7 0.4 2.8 2.8 1.8 10.3 4.7 2.6 0.0 19.1 12.1 10.2 6.5 6.8 1.9 7.8 4.6 3.0 7.5 0.8 0.0 17.5 5.7 0.5 1.7 0.4 1.0 94.0 1.0 4.0 4.3 8.9 SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1072.1" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1578.7" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Group enriched" "Detected in some" 34 "Hep G2: 39.6;RT4: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 1200000 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" 0.1 235.6 0.3 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.5 0.6 59.5 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.2 1072.1 0.0 0.2 0.2 0.3 0.1 0.1 36.9 0.0 0.1 0.2 0.1 0.9 1.0 0.1 3.1 0.1 0.3 86.6 0.0 0.0 0.4 24.4 4.2 0.2 0.0 0.1 0.0 0.1 2.0 0.1 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 39.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 26.7 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.0 0.2 0.1 2.9 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.4 0.3 0.8 0.5 0.1 0.3 0.2 0.2 0.3 0.2 0.7 0.4 0.2 0.1 0.2 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.0 0.3 2.9 0.1 0.6 0.0 0.0 1.3 0.0 0.0 0.6 18.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 18.7 0.3 0.0 0.0 0.3 5.1 0.1 0.0 0.1 30.0 1578.7 0.0 0.0 0.3 2.8 0.0 31.8 0.4 0.2 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 8.8 0.4 0.0 0.3 171.7 0.1 0.0 2.7 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.5 1.8 81.7 2.2 0.3 TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 70 "thyroid gland: 1588.2" "Cell type enhanced" "Detected in some" "Adipocytes: 24.5;Early spermatids: 4.2;Endothelial cells: 12.6;Late spermatids: 7.5;Peritubular cells: 3.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 5 "Karpas-707: 9.9;RPMI-8226: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587" Enhanced "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB009587: , HPA007987: AB_1080270" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" 13.1 0.3 0.1 0.4 0.0 0.1 11.0 0.0 0.6 0.1 0.0 4.6 0.6 0.6 0.0 2.0 0.7 3.0 11.5 0.1 0.2 0.2 0.6 0.8 1.4 0.2 0.1 0.3 2.3 0.3 0.6 0.0 0.1 0.6 0.9 0.2 3.4 0.0 6.0 1.8 3.8 0.6 0.1 22.8 2.8 1.2 0.2 0.0 1588.2 5.6 0.4 2.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.4 24.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.0 0.2 12.6 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 1.1 3.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.8 0.3 0.5 0.1 0.0 0.0 0.2 0.1 0.0 0.1 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 22.0;intestine: 79.5;stomach 1: 32.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.8;Gastric mucus-secreting cells: 3.6;Intestinal goblet cells: 1.0;Paneth cells: 1.4;Proximal enterocytes: 3.9;Squamous epithelial cells: 4.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 143 "RT4: 523.3" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 49.5 79.5 0.1 0.0 14.6 0.0 22.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 36.5 0.0 0.9 0.0 0.0 0.9 53.1 1.9 0.0 0.0 32.7 1.5 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 523.3 0.0 0.1 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718736-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 391.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.1" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 391.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 40.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "SiHa: 112.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 1.3 0.2 0.0 0.2 0.0 0.4 0.5 0.8 1.2 0.4 0.3 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.3 0.2 0.7 4.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 5.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.2 0.4 7.1 1.0 0.0 1.8 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 112.2 7.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.8 0.3 0.2 0.2 0.5 0.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 1.3 4.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 40.7 1.7 0.0 0.0 0.0 0.5 8.5 UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;liver: 20.1;urinary bladder: 30.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 4.5;Club cells: 1.0;Ionocytes: 2.0;Paneth cells: 2.5;Proximal enterocytes: 1.3;Squamous epithelial cells: 1.1" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 64 "RT4: 121.4" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 2.8 0.0 0.0 1.9 0.0 6.5 0.0 0.0 0.0 1.8 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.5 0.0 0.0 0.1 4.3 1.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.4 30.0 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.4 0.2 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671898-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 370 "kidney: 458.6;liver: 195.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 7.5;Proximal tubular cells: 6.6" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "A549: 1.4;RT4: 1.2" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 458.6 195.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enriched" "Detected in some" 18 "Proximal tubular cells: 107.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 31.4;kidney: 21.0;liver: 13.3;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 91.5;Distal enterocytes: 89.8;Hepatocytes: 53.5;Paneth cells: 54.7;Proximal enterocytes: 248.9;Proximal tubular cells: 130.8;Undifferentiated cells: 101.1" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 59 "Hep G2: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045108 Supported NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.7 9.4 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 21.0 13.3 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 91.5 0.0 3.7 0.0 0.0 0.0 89.8 11.7 26.3 0.0 0.0 0.0 0.0 12.2 2.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 53.5 0.0 0.0 0.0 34.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 54.7 0.0 0.0 0.0 248.9 130.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 101.1 0.0 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815994-68832023 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 149 "liver: 233.7" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 245.3" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 116 "Hep G2: 12.0" HPA045108 Uncertain NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA045108: AB_2679218" "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 233.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 21.0 0.1 0.0 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 245.3 0.0 0.0 0.0 0.3 0.0 7.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214748 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 239.4" "Group enriched" "Detected in some" 4 "Breast glandular cells: 13.7;Cholangiocytes: 7.2" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 4.7;eosinophil: 3.5" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.7" "Not detected" "Not detected" HPA045108 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA045108: AB_2679218" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.0 0.1 0.0 0.1 239.4 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.9 0.0 0.5 11.4 0.0 0.0 0.0 3.6 9.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.5 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 UGT2B15 UGT2B8 ENSG00000196620 "UDP glucuronosyltransferase family 2 member B15" P54855 4 68646597-68670652 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "gallbladder: 77.7;liver: 291.2" "Group enriched" "Detected in some" 6 "Cholangiocytes: 168.7;Hepatocytes: 142.8" "Cancer enriched" "Detected in many" 10 "liver cancer: 120.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA045108: AB_2679218" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (2.22e-2)" "unprognostic (3.86e-1)" "unprognostic (1.94e-1)" "prognostic favorable (9.82e-4)" "unprognostic (6.73e-2)" "unprognostic (3.49e-2)" "unprognostic (7.84e-2)" "unprognostic (5.81e-3)" "unprognostic (2.39e-2)" "unprognostic (5.38e-2)" "prognostic favorable (4.50e-4)" 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 21.6 5.1 0.0 0.0 0.0 0.1 77.7 0.0 0.0 0.0 0.0 291.2 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 13.0 0.0 0.0 0.1 17.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 4.4 0.9 0.1 168.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 24.2 3.0 0.2 0.0 0.2 0.0 2.7 0.1 3.6 0.1 0.1 0.0 0.0 0.0 0.0 2.9 142.8 0.0 0.0 0.1 3.3 0.0 3.2 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 14.6 1.1 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.9 0.1 0.6 1.0 0.0 0.0 0.0 0.4 0.0 0.5 0.9 UGT2B17 ENSG00000197888 "UDP glucuronosyltransferase family 2 member B17" O75795 4 68537184-68568527 "Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 460.0;liver: 136.2" "Group enriched" "Detected in some" 6 "Distal enterocytes: 130.1;Paneth cells: 35.1;Undifferentiated cells: 100.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 16.3;liver cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 2.8;naive B-cell: 8.8" "Lineage enriched" "Detected in single" 61 "B-cells: 8.8" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NB-4: 1.1;RPMI-8226: 1.7" HPA045108 Supported NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045108: AB_2679218" "unprognostic (1.66e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-2)" "unprognostic (2.41e-1)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.44e-3)" "unprognostic (9.67e-2)" "unprognostic (4.80e-3)" "unprognostic (8.52e-2)" "unprognostic (2.45e-1)" "unprognostic (6.44e-2)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" 0.3 0.0 0.0 38.8 0.0 0.0 0.7 0.0 0.0 1.5 0.0 365.7 364.3 1.4 1.5 0.1 0.2 0.6 0.0 0.0 0.0 0.2 136.2 0.2 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 125.8 0.0 0.2 0.7 0.0 0.0 460.0 9.1 0.1 0.6 0.8 0.0 0.1 0.4 0.0 0.0 2.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 130.1 0.0 0.0 0.0 11.1 0.1 0.0 1.8 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.4 2.8 0.0 0.0 0.1 13.8 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.3 0.1 35.1 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 100.6 0.2 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "breast: 198.5" "Cell type enriched" "Detected in single" 16 "Cholangiocytes: 10.0" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Group enriched" "Detected in some" 10 "Daudi: 2.9;NB-4: 2.7" HPA045108 Uncertain "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 198.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 883.5" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "RH-30: 4.6" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.9 0.0 0.0 1.3 1273.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 10.7 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 11.7 883.5 0.1 0.0 0.1 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.6;Glandular and luminal cells: 234.7;Hepatocytes: 550.8;Proximal tubular cells: 1249.5" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 310.8" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.2 0.0 0.0 0.3 0.0 0.0 2.3 0.0 0.0 32.0 0.0 3.8 68.7 8.9 24.2 0.2 49.9 10.4 0.0 0.0 0.0 1299.8 1612.1 0.4 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.1 0.0 0.3 6.9 0.0 3.6 27.5 0.0 0.3 66.6 0.3 0.0 0.0 0.9 0.1 0.0 0.9 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.3 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 41.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.6 0.1 310.8 2.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 43.2 0.0 0.0 0.0 0.2 0.3 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.6 1.6 0.0 0.0 1.2 0.6 0.1 38.6 2.1 125.0 0.0 0.0 0.0 5.7 97.8 6.6 0.3 150.6 14.0 1.0 3.5 2.7 0.4 10.6 0.0 0.1 0.0 234.7 0.0 0.0 8.9 550.8 0.1 0.0 0.3 37.3 0.0 13.8 0.0 0.0 1.8 7.6 3.6 0.0 0.0 0.0 0.0 1.5 0.4 13.0 10.7 0.0 0.0 0.6 70.6 1249.5 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 6.3 0.1 5.9 2.3 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 51.1;liver: 58.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 49.7;Early spermatids: 125.9;Hepatocytes: 72.1;Late spermatids: 24.5;Proximal tubular cells: 87.0" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 42 "RH-30: 28.2" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.1 58.0 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.3 0.0 0.7 0.1 0.2 3.0 0.0 6.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 49.7 0.0 0.0 0.0 0.0 3.9 0.0 125.9 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 72.1 0.1 0.0 0.3 0.7 0.0 2.6 0.0 24.5 0.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.4 0.0 0.0 3.8 87.0 0.0 0.2 6.6 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.5 0.0 1.8 0.1 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 14.7;skin 1: 10.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 3.7;Early spermatids: 4.4;Late spermatids: 8.2;Proximal tubular cells: 3.8" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.8;JURKAT: 6.3;MOLT-4: 12.4;REH: 29.9;SuSa: 11.8;T-47d: 7.2;THP-1: 18.0" "Low region specificity" "Detected in many" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.0 0.8 0.0 0.0 0.0 6.5 1.1 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 2.6 0.6 0.0 0.0 1.0 1.1 0.0 0.0 0.1 0.9 0.2 1.2 0.4 0.0 0.1 0.1 0.0 0.1 10.3 0.0 0.0 0.1 1.2 0.1 2.9 0.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.3 0.4 0.0 1.3 0.0 0.5 6.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.4 0.0 5.3 0.0 0.0 29.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.2 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.0 1.1 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.7 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 1.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0