[{"Gene":"NTPCR","Gene synonym":["C1orf57","HCR-NTPase","MGC13186","THEP1"],"Ensembl":"ENSG00000135778","Gene description":"Nucleoside-triphosphatase, cancer-related","Uniprot":["Q9BSD7"],"Chromosome":"1","Position":"232950605-232983882","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028125","HPA054304"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028125":"AB_10601091","HPA054304":"AB_2682443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"9.0","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"11.4","Tissue RNA - midbrain [nTPM]":"9.3","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"8.0","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"13.5","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"3.0","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"2.7","Cell RNA - ASC diff [nTPM]":"4.0","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"3.1","Cell RNA - EFO-21 [nTPM]":"2.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.7","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"5.0","Cell RNA - HBF TERT88 [nTPM]":"4.4","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.9","Cell RNA - hTERT-HME1 [nTPM]":"3.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.3","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"2.8","Cell RNA - Karpas-707 [nTPM]":"4.6","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"3.5","Cell RNA - RPMI-8226 [nTPM]":"4.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"2.4","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"1.6","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"4.0","Cell RNA - T-47d [nTPM]":"4.0","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"2.7","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"3.5","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"4.1","Cell RNA - WM-115 [nTPM]":"4.9","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"9.0","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"11.4","Brain RNA - midbrain [nTPM]":"9.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"45.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.1","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"15.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"36.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"68.9","Single Cell Type RNA - dendritic cells [nTPM]":"16.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"93.9","Single Cell Type RNA - Ductal cells [nTPM]":"62.2","Single Cell Type RNA - Early spermatids [nTPM]":"47.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"64.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.1","Single Cell Type RNA - Fibroblasts [nTPM]":"33.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.7","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"44.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"34.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.3","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.0","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"22.8","Single Cell Type RNA - Langerhans cells [nTPM]":"17.3","Single Cell Type RNA - Late spermatids [nTPM]":"27.3","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"21.2","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"30.1","Single Cell Type RNA - Muller glia cells [nTPM]":"41.0","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.5","Single Cell Type RNA - Paneth cells [nTPM]":"31.2","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"82.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.7","Single Cell Type RNA - Spermatocytes [nTPM]":"86.5","Single Cell Type RNA - Spermatogonia [nTPM]":"40.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"67.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"66.5","Single Cell Type RNA - Urothelial cells [nTPM]":"41.6"},{"Gene":"PDHA1","Gene synonym":["PDHA"],"Ensembl":"ENSG00000131828","Gene description":"Pyruvate dehydrogenase E1 subunit alpha 1","Uniprot":["P08559"],"Chromosome":"X","Position":"19343893-19361718","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"508.8","tongue":"770.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"479.9","Distal tubular cells":"354.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047487","HPA047864","HPA063053"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047487":"AB_2680066","HPA047864":"AB_2680190","HPA063053":"AB_2684931"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"93.0","Tissue RNA - adrenal gland [nTPM]":"69.0","Tissue RNA - amygdala [nTPM]":"62.1","Tissue RNA - appendix [nTPM]":"37.9","Tissue RNA - basal ganglia [nTPM]":"66.9","Tissue RNA - bone marrow [nTPM]":"88.1","Tissue RNA - breast [nTPM]":"63.1","Tissue RNA - cerebellum [nTPM]":"66.2","Tissue RNA - cerebral cortex [nTPM]":"91.5","Tissue RNA - cervix [nTPM]":"55.9","Tissue RNA - choroid plexus [nTPM]":"84.4","Tissue RNA - colon [nTPM]":"112.6","Tissue RNA - duodenum [nTPM]":"87.0","Tissue RNA - endometrium 1 [nTPM]":"53.1","Tissue RNA - epididymis [nTPM]":"78.9","Tissue RNA - esophagus [nTPM]":"76.8","Tissue RNA - fallopian tube [nTPM]":"49.1","Tissue RNA - gallbladder [nTPM]":"29.3","Tissue RNA - heart muscle [nTPM]":"508.8","Tissue RNA - hippocampal formation [nTPM]":"68.2","Tissue RNA - hypothalamus [nTPM]":"67.0","Tissue RNA - kidney [nTPM]":"174.1","Tissue RNA - liver [nTPM]":"118.3","Tissue RNA - lung [nTPM]":"47.2","Tissue RNA - lymph node [nTPM]":"36.6","Tissue RNA - medulla oblongata [nTPM]":"64.5","Tissue RNA - midbrain [nTPM]":"62.7","Tissue RNA - ovary [nTPM]":"50.6","Tissue RNA - pancreas [nTPM]":"83.4","Tissue RNA - parathyroid gland [nTPM]":"161.0","Tissue RNA - pituitary gland [nTPM]":"48.7","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"65.0","Tissue RNA - prostate [nTPM]":"48.4","Tissue RNA - rectum [nTPM]":"104.4","Tissue RNA - retina [nTPM]":"90.1","Tissue RNA - salivary gland [nTPM]":"109.7","Tissue RNA - seminal vesicle [nTPM]":"63.4","Tissue RNA - skeletal muscle [nTPM]":"459.0","Tissue RNA - skin 1 [nTPM]":"60.9","Tissue RNA - small intestine [nTPM]":"82.1","Tissue RNA - smooth muscle [nTPM]":"51.8","Tissue RNA - spinal cord [nTPM]":"59.6","Tissue RNA - spleen [nTPM]":"49.3","Tissue RNA - stomach 1 [nTPM]":"121.8","Tissue RNA - testis [nTPM]":"24.0","Tissue RNA - thalamus [nTPM]":"67.4","Tissue RNA - thymus [nTPM]":"52.3","Tissue RNA - thyroid gland [nTPM]":"64.5","Tissue RNA - tongue [nTPM]":"770.2","Tissue RNA - tonsil [nTPM]":"59.1","Tissue RNA - urinary bladder [nTPM]":"61.7","Tissue RNA - vagina [nTPM]":"56.1","Tissue RNA - white matter [nTPM]":"71.1","Cell RNA - A-431 [nTPM]":"124.9","Cell RNA - A549 [nTPM]":"151.4","Cell RNA - AF22 [nTPM]":"107.9","Cell RNA - AN3-CA [nTPM]":"114.2","Cell RNA - ASC diff [nTPM]":"102.3","Cell RNA - ASC TERT1 [nTPM]":"77.7","Cell RNA - BEWO [nTPM]":"131.6","Cell RNA - BJ [nTPM]":"83.8","Cell RNA - BJ hTERT+ [nTPM]":"74.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"170.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"130.7","Cell RNA - CACO-2 [nTPM]":"216.6","Cell RNA - CAPAN-2 [nTPM]":"78.2","Cell RNA - Daudi [nTPM]":"212.2","Cell RNA - EFO-21 [nTPM]":"60.6","Cell RNA - fHDF\/TERT166 [nTPM]":"102.0","Cell RNA - GAMG [nTPM]":"226.7","Cell RNA - HaCaT [nTPM]":"159.0","Cell RNA - HAP1 [nTPM]":"334.2","Cell RNA - HBEC3-KT [nTPM]":"145.8","Cell RNA - HBF TERT88 [nTPM]":"178.1","Cell RNA - HDLM-2 [nTPM]":"70.1","Cell RNA - HEK 293 [nTPM]":"186.1","Cell RNA - HEL [nTPM]":"104.8","Cell RNA - HeLa [nTPM]":"264.0","Cell RNA - Hep G2 [nTPM]":"194.2","Cell RNA - HHSteC [nTPM]":"107.8","Cell RNA - HL-60 [nTPM]":"170.3","Cell RNA - HMC-1 [nTPM]":"82.8","Cell RNA - HSkMC [nTPM]":"100.9","Cell RNA - hTCEpi [nTPM]":"132.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"157.3","Cell RNA - hTERT-HME1 [nTPM]":"154.4","Cell RNA - hTERT-RPE1 [nTPM]":"85.6","Cell RNA - HUVEC TERT2 [nTPM]":"105.3","Cell RNA - JURKAT [nTPM]":"129.8","Cell RNA - K-562 [nTPM]":"94.2","Cell RNA - Karpas-707 [nTPM]":"87.2","Cell RNA - LHCN-M2 [nTPM]":"120.7","Cell RNA - MCF7 [nTPM]":"164.5","Cell RNA - MOLT-4 [nTPM]":"142.7","Cell RNA - NB-4 [nTPM]":"173.5","Cell RNA - NTERA-2 [nTPM]":"110.0","Cell RNA - OE19 [nTPM]":"227.4","Cell RNA - PC-3 [nTPM]":"261.7","Cell RNA - REH [nTPM]":"145.2","Cell RNA - RH-30 [nTPM]":"180.9","Cell RNA - RPMI-8226 [nTPM]":"260.3","Cell RNA - RPTEC TERT1 [nTPM]":"298.0","Cell RNA - RT4 [nTPM]":"125.1","Cell RNA - SCLC-21H [nTPM]":"59.7","Cell RNA - SH-SY5Y [nTPM]":"62.6","Cell RNA - SiHa [nTPM]":"134.1","Cell RNA - SK-BR-3 [nTPM]":"167.8","Cell RNA - SK-MEL-30 [nTPM]":"158.1","Cell RNA - SuSa [nTPM]":"229.8","Cell RNA - T-47d [nTPM]":"177.1","Cell RNA - THP-1 [nTPM]":"118.1","Cell RNA - TIME [nTPM]":"65.4","Cell RNA - U-138 MG [nTPM]":"87.6","Cell RNA - U-2 OS [nTPM]":"78.6","Cell RNA - U-2197 [nTPM]":"240.9","Cell RNA - U-251 MG [nTPM]":"108.6","Cell RNA - U-266\/70 [nTPM]":"73.3","Cell RNA - U-266\/84 [nTPM]":"82.0","Cell RNA - U-698 [nTPM]":"140.5","Cell RNA - U-87 MG [nTPM]":"82.4","Cell RNA - U-937 [nTPM]":"117.2","Cell RNA - WM-115 [nTPM]":"77.4","Blood RNA - basophil [nTPM]":"99.9","Blood RNA - classical monocyte [nTPM]":"87.4","Blood RNA - eosinophil [nTPM]":"65.3","Blood RNA - gdT-cell [nTPM]":"72.3","Blood RNA - intermediate monocyte [nTPM]":"119.9","Blood RNA - MAIT T-cell [nTPM]":"88.9","Blood RNA - memory B-cell [nTPM]":"103.4","Blood RNA - memory CD4 T-cell [nTPM]":"69.4","Blood RNA - memory CD8 T-cell [nTPM]":"79.5","Blood RNA - myeloid DC [nTPM]":"115.7","Blood RNA - naive B-cell [nTPM]":"82.1","Blood RNA - naive CD4 T-cell [nTPM]":"67.7","Blood RNA - naive CD8 T-cell [nTPM]":"72.0","Blood RNA - neutrophil [nTPM]":"15.5","Blood RNA - NK-cell [nTPM]":"98.1","Blood RNA - non-classical monocyte [nTPM]":"109.1","Blood RNA - plasmacytoid DC [nTPM]":"76.9","Blood RNA - T-reg [nTPM]":"84.4","Blood RNA - total PBMC [nTPM]":"89.6","Brain RNA - amygdala [nTPM]":"62.1","Brain RNA - basal ganglia [nTPM]":"66.9","Brain RNA - cerebellum [nTPM]":"66.2","Brain RNA - cerebral cortex [nTPM]":"91.5","Brain RNA - hippocampal formation [nTPM]":"68.2","Brain RNA - hypothalamus [nTPM]":"67.0","Brain RNA - medulla oblongata [nTPM]":"64.5","Brain RNA - midbrain [nTPM]":"62.7","Brain RNA - pons [nTPM]":"65.0","Brain RNA - spinal cord [nTPM]":"59.6","Brain RNA - thalamus [nTPM]":"67.4","Brain RNA - white matter [nTPM]":"71.1","Single Cell Type RNA - Adipocytes [nTPM]":"34.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"44.4","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"30.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"135.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"59.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"479.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"74.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"152.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"105.0","Single Cell Type RNA - dendritic cells [nTPM]":"32.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"73.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"88.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.7","Single Cell Type RNA - Endothelial cells [nTPM]":"36.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.9","Single Cell Type RNA - Erythroid cells [nTPM]":"55.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"120.7","Single Cell Type RNA - Fibroblasts [nTPM]":"49.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"42.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"76.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"73.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"64.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"26.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"35.4","Single Cell Type RNA - Macrophages [nTPM]":"32.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"49.0","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.4","Single Cell Type RNA - Paneth cells [nTPM]":"52.5","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"43.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"47.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"213.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.7","Single Cell Type RNA - Spermatocytes [nTPM]":"51.1","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"133.4","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"25.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"130.3","Single Cell Type RNA - Urothelial cells [nTPM]":"55.8"},{"Gene":"PDHA2","Gene synonym":["PDHAL"],"Ensembl":"ENSG00000163114","Gene description":"Pyruvate dehydrogenase E1 subunit alpha 2","Uniprot":["P29803"],"Chromosome":"4","Position":"95840093-95841464","Protein class":["Citric acid cycle related proteins","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"602","RNA tissue specific nTPM":{"testis":"60.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"71","RNA single cell type specific nTPM":{"Early spermatids":"426.6","Late spermatids":"288.3","Spermatocytes":"229.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047487","HPA047864","HPA063053"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047487":"AB_2680066","HPA047864":"AB_2680190","HPA063053":"AB_2684931"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"60.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"426.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"288.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.4","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"229.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PDHB","Gene synonym":["PDHE1B"],"Ensembl":"ENSG00000168291","Gene description":"Pyruvate dehydrogenase E1 subunit beta","Uniprot":["P11177"],"Chromosome":"3","Position":"58427630-58433857","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"299.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"300.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033794","HPA036744","HPA036745"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"61000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB033794":"AB_2162946","HPA036744":"AB_10670921","HPA036745":"AB_2675285"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.9","Tissue RNA - adrenal gland [nTPM]":"76.5","Tissue RNA - amygdala [nTPM]":"48.7","Tissue RNA - appendix [nTPM]":"42.2","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"25.7","Tissue RNA - breast [nTPM]":"42.9","Tissue RNA - cerebellum [nTPM]":"53.9","Tissue RNA - cerebral cortex [nTPM]":"62.7","Tissue RNA - cervix [nTPM]":"43.3","Tissue RNA - choroid plexus [nTPM]":"63.6","Tissue RNA - colon [nTPM]":"56.8","Tissue RNA - duodenum [nTPM]":"42.5","Tissue RNA - endometrium 1 [nTPM]":"38.5","Tissue RNA - epididymis [nTPM]":"44.6","Tissue RNA - esophagus [nTPM]":"57.4","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"35.9","Tissue RNA - heart muscle [nTPM]":"175.0","Tissue RNA - hippocampal formation [nTPM]":"49.7","Tissue RNA - hypothalamus [nTPM]":"52.3","Tissue RNA - kidney [nTPM]":"100.8","Tissue RNA - liver [nTPM]":"110.7","Tissue RNA - lung [nTPM]":"36.4","Tissue RNA - lymph node [nTPM]":"53.1","Tissue RNA - medulla oblongata [nTPM]":"51.7","Tissue RNA - midbrain [nTPM]":"49.4","Tissue RNA - ovary [nTPM]":"26.5","Tissue RNA - pancreas [nTPM]":"36.4","Tissue RNA - parathyroid gland [nTPM]":"88.8","Tissue RNA - pituitary gland [nTPM]":"44.1","Tissue RNA - placenta [nTPM]":"57.0","Tissue RNA - pons [nTPM]":"51.5","Tissue RNA - prostate [nTPM]":"48.5","Tissue RNA - rectum [nTPM]":"60.4","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"45.9","Tissue RNA - seminal vesicle [nTPM]":"52.1","Tissue RNA - skeletal muscle [nTPM]":"272.6","Tissue RNA - skin 1 [nTPM]":"36.8","Tissue RNA - small intestine [nTPM]":"37.6","Tissue RNA - smooth muscle [nTPM]":"63.8","Tissue RNA - spinal cord [nTPM]":"51.6","Tissue RNA - spleen [nTPM]":"42.8","Tissue RNA - stomach 1 [nTPM]":"53.9","Tissue RNA - testis [nTPM]":"42.3","Tissue RNA - thalamus [nTPM]":"53.1","Tissue RNA - thymus [nTPM]":"53.1","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"299.4","Tissue RNA - tonsil [nTPM]":"56.0","Tissue RNA - urinary bladder [nTPM]":"49.7","Tissue RNA - vagina [nTPM]":"35.9","Tissue RNA - white matter [nTPM]":"54.3","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"90.9","Cell RNA - AF22 [nTPM]":"92.3","Cell RNA - AN3-CA [nTPM]":"69.8","Cell RNA - ASC diff [nTPM]":"91.7","Cell RNA - ASC TERT1 [nTPM]":"111.1","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"81.6","Cell RNA - BJ hTERT+ [nTPM]":"101.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"117.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"120.6","Cell RNA - CACO-2 [nTPM]":"165.1","Cell RNA - CAPAN-2 [nTPM]":"62.6","Cell RNA - Daudi [nTPM]":"140.3","Cell RNA - EFO-21 [nTPM]":"44.9","Cell RNA - fHDF\/TERT166 [nTPM]":"103.8","Cell RNA - GAMG [nTPM]":"109.0","Cell RNA - HaCaT [nTPM]":"37.6","Cell RNA - HAP1 [nTPM]":"113.2","Cell RNA - HBEC3-KT [nTPM]":"74.9","Cell RNA - HBF TERT88 [nTPM]":"90.0","Cell RNA - HDLM-2 [nTPM]":"81.7","Cell RNA - HEK 293 [nTPM]":"83.0","Cell RNA - HEL [nTPM]":"125.4","Cell RNA - HeLa [nTPM]":"163.7","Cell RNA - Hep G2 [nTPM]":"126.0","Cell RNA - HHSteC [nTPM]":"92.5","Cell RNA - HL-60 [nTPM]":"103.0","Cell RNA - HMC-1 [nTPM]":"67.9","Cell RNA - HSkMC [nTPM]":"97.9","Cell RNA - hTCEpi [nTPM]":"67.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"95.5","Cell RNA - hTERT-HME1 [nTPM]":"55.8","Cell RNA - hTERT-RPE1 [nTPM]":"137.5","Cell RNA - HUVEC TERT2 [nTPM]":"103.1","Cell RNA - JURKAT [nTPM]":"114.2","Cell RNA - K-562 [nTPM]":"65.9","Cell RNA - Karpas-707 [nTPM]":"61.5","Cell RNA - LHCN-M2 [nTPM]":"129.5","Cell RNA - MCF7 [nTPM]":"63.1","Cell RNA - MOLT-4 [nTPM]":"98.2","Cell RNA - NB-4 [nTPM]":"107.8","Cell RNA - NTERA-2 [nTPM]":"127.2","Cell RNA - OE19 [nTPM]":"69.2","Cell RNA - PC-3 [nTPM]":"101.3","Cell RNA - REH [nTPM]":"46.3","Cell RNA - RH-30 [nTPM]":"71.8","Cell RNA - RPMI-8226 [nTPM]":"136.1","Cell RNA - RPTEC TERT1 [nTPM]":"188.1","Cell RNA - RT4 [nTPM]":"89.1","Cell RNA - SCLC-21H [nTPM]":"63.7","Cell RNA - SH-SY5Y [nTPM]":"70.2","Cell RNA - SiHa [nTPM]":"75.6","Cell RNA - SK-BR-3 [nTPM]":"107.2","Cell RNA - SK-MEL-30 [nTPM]":"85.4","Cell RNA - SuSa [nTPM]":"131.3","Cell RNA - T-47d [nTPM]":"159.0","Cell RNA - THP-1 [nTPM]":"108.7","Cell RNA - TIME [nTPM]":"76.3","Cell RNA - U-138 MG [nTPM]":"62.9","Cell RNA - U-2 OS [nTPM]":"83.7","Cell RNA - U-2197 [nTPM]":"66.8","Cell RNA - U-251 MG [nTPM]":"94.2","Cell RNA - U-266\/70 [nTPM]":"85.2","Cell RNA - U-266\/84 [nTPM]":"129.9","Cell RNA - U-698 [nTPM]":"99.2","Cell RNA - U-87 MG [nTPM]":"96.2","Cell RNA - U-937 [nTPM]":"120.8","Cell RNA - WM-115 [nTPM]":"60.7","Blood RNA - basophil [nTPM]":"57.8","Blood RNA - classical monocyte [nTPM]":"98.9","Blood RNA - eosinophil [nTPM]":"98.7","Blood RNA - gdT-cell [nTPM]":"83.2","Blood RNA - intermediate monocyte [nTPM]":"115.1","Blood RNA - MAIT T-cell [nTPM]":"87.9","Blood RNA - memory B-cell [nTPM]":"102.2","Blood RNA - memory CD4 T-cell [nTPM]":"81.7","Blood RNA - memory CD8 T-cell [nTPM]":"80.5","Blood RNA - myeloid DC [nTPM]":"141.1","Blood RNA - naive B-cell [nTPM]":"103.4","Blood RNA - naive CD4 T-cell [nTPM]":"90.9","Blood RNA - naive CD8 T-cell [nTPM]":"82.4","Blood RNA - neutrophil [nTPM]":"19.6","Blood RNA - NK-cell [nTPM]":"129.4","Blood RNA - non-classical monocyte [nTPM]":"109.7","Blood RNA - plasmacytoid DC [nTPM]":"94.7","Blood RNA - T-reg [nTPM]":"113.2","Blood RNA - total PBMC [nTPM]":"124.1","Brain RNA - amygdala [nTPM]":"48.7","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"53.9","Brain RNA - cerebral cortex [nTPM]":"62.7","Brain RNA - hippocampal formation [nTPM]":"49.7","Brain RNA - hypothalamus [nTPM]":"52.3","Brain RNA - medulla oblongata [nTPM]":"51.7","Brain RNA - midbrain [nTPM]":"49.4","Brain RNA - pons [nTPM]":"51.5","Brain RNA - spinal cord [nTPM]":"51.6","Brain RNA - thalamus [nTPM]":"53.1","Brain RNA - white matter [nTPM]":"54.3","Single Cell Type RNA - Adipocytes [nTPM]":"57.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"45.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"40.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"142.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Bipolar cells [nTPM]":"31.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"300.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"96.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"174.1","Single Cell Type RNA - dendritic cells [nTPM]":"35.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"230.9","Single Cell Type RNA - Ductal cells [nTPM]":"95.9","Single Cell Type RNA - Early spermatids [nTPM]":"76.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.3","Single Cell Type RNA - Endothelial cells [nTPM]":"58.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"101.6","Single Cell Type RNA - Fibroblasts [nTPM]":"54.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.2","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"48.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.1","Single Cell Type RNA - Hepatocytes [nTPM]":"76.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"84.6","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.4","Single Cell Type RNA - Ionocytes [nTPM]":"162.8","Single Cell Type RNA - Kupffer cells [nTPM]":"37.9","Single Cell Type RNA - Langerhans cells [nTPM]":"26.6","Single Cell Type RNA - Late spermatids [nTPM]":"16.9","Single Cell Type RNA - Leydig cells [nTPM]":"60.3","Single Cell Type RNA - Macrophages [nTPM]":"37.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"76.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.7","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"55.9","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"72.3","Single Cell Type RNA - Spermatocytes [nTPM]":"98.2","Single Cell Type RNA - Spermatogonia [nTPM]":"88.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"157.2","Single Cell Type RNA - T-cells [nTPM]":"44.7","Single Cell Type RNA - Theca cells [nTPM]":"224.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.0","Single Cell Type RNA - Urothelial cells [nTPM]":"37.7"},{"Gene":"THTPA","Gene synonym":["THTPASE"],"Ensembl":"ENSG00000259431","Gene description":"Thiamine triphosphatase","Uniprot":["Q9BU02"],"Chromosome":"14","Position":"23555988-23560271","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"54.8","Spermatocytes":"57.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA028876":"AB_10600731"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.6","Tissue RNA - adrenal gland [nTPM]":"17.6","Tissue RNA - amygdala [nTPM]":"29.3","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"41.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"27.5","Tissue RNA - cerebral cortex [nTPM]":"33.0","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"28.5","Tissue RNA - colon [nTPM]":"11.5","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"8.5","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"14.8","Tissue RNA - hippocampal formation [nTPM]":"30.1","Tissue RNA - hypothalamus [nTPM]":"27.0","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"11.3","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"28.4","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"6.7","Tissue RNA - pons [nTPM]":"27.7","Tissue RNA - prostate [nTPM]":"16.0","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"17.3","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"23.6","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"10.7","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"20.1","Tissue RNA - thalamus [nTPM]":"27.9","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"20.7","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"10.2","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"29.3","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"24.1","Cell RNA - AF22 [nTPM]":"11.4","Cell RNA - AN3-CA [nTPM]":"12.4","Cell RNA - ASC diff [nTPM]":"26.3","Cell RNA - ASC TERT1 [nTPM]":"14.6","Cell RNA - BEWO [nTPM]":"6.3","Cell RNA - BJ [nTPM]":"11.2","Cell RNA - BJ hTERT+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.5","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"15.9","Cell RNA - Daudi [nTPM]":"7.2","Cell RNA - EFO-21 [nTPM]":"9.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"12.1","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"13.8","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"15.9","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"10.2","Cell RNA - HeLa [nTPM]":"16.9","Cell RNA - Hep G2 [nTPM]":"13.3","Cell RNA - HHSteC [nTPM]":"13.0","Cell RNA - HL-60 [nTPM]":"9.1","Cell RNA - HMC-1 [nTPM]":"8.7","Cell RNA - HSkMC [nTPM]":"20.6","Cell RNA - hTCEpi [nTPM]":"10.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.4","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"22.9","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"11.6","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"15.9","Cell RNA - LHCN-M2 [nTPM]":"15.7","Cell RNA - MCF7 [nTPM]":"11.6","Cell RNA - MOLT-4 [nTPM]":"14.6","Cell RNA - NB-4 [nTPM]":"3.7","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"20.9","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"13.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.9","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"10.8","Cell RNA - SK-BR-3 [nTPM]":"22.0","Cell RNA - SK-MEL-30 [nTPM]":"6.6","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"4.4","Cell RNA - TIME [nTPM]":"10.9","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"6.5","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"12.2","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"4.2","Cell RNA - WM-115 [nTPM]":"10.9","Blood RNA - basophil [nTPM]":"13.7","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"9.8","Blood RNA - intermediate monocyte [nTPM]":"12.0","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"10.2","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"11.7","Blood RNA - naive CD8 T-cell [nTPM]":"10.2","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"16.1","Blood RNA - plasmacytoid DC [nTPM]":"18.7","Blood RNA - T-reg [nTPM]":"6.4","Blood RNA - total PBMC [nTPM]":"10.9","Brain RNA - amygdala [nTPM]":"29.3","Brain RNA - basal ganglia [nTPM]":"41.7","Brain RNA - cerebellum [nTPM]":"27.5","Brain RNA - cerebral cortex [nTPM]":"33.0","Brain RNA - hippocampal formation [nTPM]":"30.1","Brain RNA - hypothalamus [nTPM]":"27.0","Brain RNA - medulla oblongata [nTPM]":"28.4","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"27.7","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"27.9","Brain RNA - white matter [nTPM]":"29.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"27.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"14.5","Single Cell Type RNA - Early spermatids [nTPM]":"21.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.2","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"23.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"10.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"23.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"9.9","Single Cell Type RNA - Muller glia cells [nTPM]":"33.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"57.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"TPK1","Gene synonym":["HTPK1","PP20"],"Ensembl":"ENSG00000196511","Gene description":"Thiamin pyrophosphokinase 1","Uniprot":["Q9H3S4"],"Chromosome":"7","Position":"144451941-144836395","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"14.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"83.0","Excitatory neurons":"82.6","Inhibitory neurons":"76.3","Late spermatids":"95.8","Microglial cells":"110.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"70.6","CACO-2":"17.2","EFO-21":"21.2","TIME":"16.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021545","HPA021849"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021545":"AB_1858209","HPA021849":"AB_1858210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"4.2","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"14.3","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"5.2","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"5.2","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"1.6","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"4.3","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"70.6","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"17.2","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"21.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"4.3","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"5.5","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"6.3","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"16.3","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"13.8","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"10.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"7.4","Blood RNA - MAIT T-cell [nTPM]":"5.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"13.2","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"4.7","Blood RNA - NK-cell [nTPM]":"5.8","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"7.7","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"5.2","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.3","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"23.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.2","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"83.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"82.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.6","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"6.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"5.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"95.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"17.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"110.5","Single Cell Type RNA - monocytes [nTPM]":"15.7","Single Cell Type RNA - Muller glia cells [nTPM]":"3.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"14.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"}]