[{"Gene":"AOX1","Gene synonym":["AO","AOH1"],"Ensembl":"ENSG00000138356","Gene description":"Aldehyde oxidase 1","Uniprot":["Q06278"],"Chromosome":"2","Position":"200586014-200677064","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adrenal gland":"300.5","liver":"891.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"749.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"122.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"377.3","ASC TERT1":"191.5","HSkMC":"78.2","hTERT-HME1":"81.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040199","HPA040215"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040199":"AB_10795273","HPA040215":"AB_10795360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"87.6","Tissue RNA - adrenal gland [nTPM]":"300.5","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"17.9","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"48.2","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"103.2","Tissue RNA - liver [nTPM]":"891.0","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"48.0","Tissue RNA - pancreas [nTPM]":"85.0","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"1.7","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"22.3","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"15.3","Tissue RNA - seminal vesicle [nTPM]":"28.3","Tissue RNA - skeletal muscle [nTPM]":"12.9","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"12.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"14.3","Tissue RNA - testis [nTPM]":"19.4","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"17.7","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"38.6","Tissue RNA - vagina [nTPM]":"17.7","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"377.3","Cell RNA - ASC TERT1 [nTPM]":"191.5","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"18.6","Cell RNA - HBF TERT88 [nTPM]":"22.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.6","Cell RNA - Hep G2 [nTPM]":"20.7","Cell RNA - HHSteC [nTPM]":"25.4","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"78.2","Cell RNA - hTCEpi [nTPM]":"4.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.1","Cell RNA - hTERT-HME1 [nTPM]":"81.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"31.9","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"11.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"2.6","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"22.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"749.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"74.0","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"82.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"162.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"KLHL23","Gene synonym":["FLJ37812","MGC22679","MGC2610"],"Ensembl":"ENSG00000213160","Gene description":"Kelch like family member 23","Uniprot":["Q8NBE8"],"Chromosome":"2","Position":"169694488-169776989","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"132.5","Cone photoreceptor cells":"89.6","Sertoli cells":"170.9","Smooth muscle cells":"102.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"83.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047593"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA047593":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"9.6","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"25.6","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"17.9","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"12.8","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"13.6","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"12.5","Tissue RNA - skeletal muscle [nTPM]":"12.0","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"25.0","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"5.1","Tissue RNA - testis [nTPM]":"10.9","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"16.3","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"17.0","Cell RNA - A549 [nTPM]":"8.6","Cell RNA - AF22 [nTPM]":"64.5","Cell RNA - AN3-CA [nTPM]":"18.3","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"43.7","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"18.0","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"10.6","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"20.9","Cell RNA - HaCaT [nTPM]":"2.6","Cell RNA - HAP1 [nTPM]":"67.7","Cell RNA - HBEC3-KT [nTPM]":"5.8","Cell RNA - HBF TERT88 [nTPM]":"21.9","Cell RNA - HDLM-2 [nTPM]":"37.7","Cell RNA - HEK 293 [nTPM]":"33.2","Cell RNA - HEL [nTPM]":"31.3","Cell RNA - HeLa [nTPM]":"16.9","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"44.2","Cell RNA - HMC-1 [nTPM]":"4.7","Cell RNA - HSkMC [nTPM]":"2.5","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"10.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"38.3","Cell RNA - K-562 [nTPM]":"43.5","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"8.2","Cell RNA - MOLT-4 [nTPM]":"65.0","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"52.7","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"20.7","Cell RNA - RH-30 [nTPM]":"55.1","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"49.9","Cell RNA - SCLC-21H [nTPM]":"83.4","Cell RNA - SH-SY5Y [nTPM]":"57.1","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"20.3","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"14.2","Cell RNA - TIME [nTPM]":"4.2","Cell RNA - U-138 MG [nTPM]":"5.8","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"4.9","Cell RNA - U-266\/84 [nTPM]":"4.9","Cell RNA - U-698 [nTPM]":"47.3","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"13.0","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"9.6","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"132.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.6","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"27.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"11.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.2","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"34.8","Single Cell Type RNA - Sertoli cells [nTPM]":"170.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"5.5","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"PDXK","Gene synonym":["C21orf124","C21orf97","FLJ21324","FLJ31940","MGC15873","PKH","PNK","PRED79"],"Ensembl":"ENSG00000160209","Gene description":"Pyridoxal kinase","Uniprot":["O00764"],"Chromosome":"21","Position":"43719094-43762307","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","FDA approved drug targets","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"87.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"1717.4","Late spermatids":"4366.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030196","HPA030197","HPA030198","CAB033918"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"830000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB033918":"AB_2162502","HPA030196":"AB_10599735","HPA030197":"AB_10601792","HPA030198":"AB_10603570"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Tissue RNA - adipose tissue [nTPM]":"25.6","Tissue RNA - adrenal gland [nTPM]":"21.8","Tissue RNA - amygdala [nTPM]":"79.4","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"62.2","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"18.4","Tissue RNA - cerebellum [nTPM]":"23.9","Tissue RNA - cerebral cortex [nTPM]":"87.0","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"17.5","Tissue RNA - colon [nTPM]":"17.1","Tissue RNA - duodenum [nTPM]":"14.1","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"19.7","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"62.5","Tissue RNA - hypothalamus [nTPM]":"51.7","Tissue RNA - kidney [nTPM]":"50.4","Tissue RNA - liver [nTPM]":"21.5","Tissue RNA - lung [nTPM]":"20.9","Tissue RNA - lymph node [nTPM]":"7.0","Tissue RNA - medulla oblongata [nTPM]":"48.8","Tissue RNA - midbrain [nTPM]":"59.7","Tissue RNA - ovary [nTPM]":"19.1","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"17.8","Tissue RNA - pituitary gland [nTPM]":"37.3","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"54.7","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"9.4","Tissue RNA - retina [nTPM]":"10.0","Tissue RNA - salivary gland [nTPM]":"22.7","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"13.9","Tissue RNA - small intestine [nTPM]":"19.7","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"34.4","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"70.5","Tissue RNA - thymus [nTPM]":"10.2","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"9.3","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"12.6","Tissue RNA - white matter [nTPM]":"57.6","Cell RNA - A-431 [nTPM]":"43.4","Cell RNA - A549 [nTPM]":"51.9","Cell RNA - AF22 [nTPM]":"8.1","Cell RNA - AN3-CA [nTPM]":"15.5","Cell RNA - ASC diff [nTPM]":"19.4","Cell RNA - ASC TERT1 [nTPM]":"27.3","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"15.2","Cell RNA - BJ hTERT+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.1","Cell RNA - CACO-2 [nTPM]":"42.5","Cell RNA - CAPAN-2 [nTPM]":"65.7","Cell RNA - Daudi [nTPM]":"14.4","Cell RNA - EFO-21 [nTPM]":"15.7","Cell RNA - fHDF\/TERT166 [nTPM]":"21.9","Cell RNA - GAMG [nTPM]":"20.0","Cell RNA - HaCaT [nTPM]":"31.9","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"43.4","Cell RNA - HBF TERT88 [nTPM]":"9.5","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"14.7","Cell RNA - HeLa [nTPM]":"60.9","Cell RNA - Hep G2 [nTPM]":"31.7","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"14.0","Cell RNA - HMC-1 [nTPM]":"20.6","Cell RNA - HSkMC [nTPM]":"38.9","Cell RNA - hTCEpi [nTPM]":"40.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.3","Cell RNA - hTERT-HME1 [nTPM]":"16.9","Cell RNA - hTERT-RPE1 [nTPM]":"23.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"6.3","Cell RNA - K-562 [nTPM]":"26.2","Cell RNA - Karpas-707 [nTPM]":"31.9","Cell RNA - LHCN-M2 [nTPM]":"13.8","Cell RNA - MCF7 [nTPM]":"29.1","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"24.9","Cell RNA - NTERA-2 [nTPM]":"22.3","Cell RNA - OE19 [nTPM]":"41.9","Cell RNA - PC-3 [nTPM]":"19.7","Cell RNA - REH [nTPM]":"16.7","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"40.4","Cell RNA - RPTEC TERT1 [nTPM]":"62.9","Cell RNA - RT4 [nTPM]":"51.9","Cell RNA - SCLC-21H [nTPM]":"7.8","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"63.3","Cell RNA - SK-BR-3 [nTPM]":"57.7","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"3.3","Cell RNA - T-47d [nTPM]":"19.0","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"12.5","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"14.4","Cell RNA - U-266\/70 [nTPM]":"19.3","Cell RNA - U-266\/84 [nTPM]":"9.8","Cell RNA - U-698 [nTPM]":"8.4","Cell RNA - U-87 MG [nTPM]":"43.2","Cell RNA - U-937 [nTPM]":"39.9","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"79.4","Brain RNA - basal ganglia [nTPM]":"62.2","Brain RNA - cerebellum [nTPM]":"23.9","Brain RNA - cerebral cortex [nTPM]":"87.0","Brain RNA - hippocampal formation [nTPM]":"62.5","Brain RNA - hypothalamus [nTPM]":"51.7","Brain RNA - medulla oblongata [nTPM]":"48.8","Brain RNA - midbrain [nTPM]":"59.7","Brain RNA - pons [nTPM]":"54.7","Brain RNA - spinal cord [nTPM]":"34.4","Brain RNA - thalamus [nTPM]":"70.5","Brain RNA - white matter [nTPM]":"57.6","Single Cell Type RNA - Adipocytes [nTPM]":"15.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"66.6","Single Cell Type RNA - Astrocytes [nTPM]":"44.1","Single Cell Type RNA - B-cells [nTPM]":"37.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"142.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"72.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"46.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"74.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"73.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"101.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.9","Single Cell Type RNA - dendritic cells [nTPM]":"23.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"97.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"180.0","Single Cell Type RNA - Ductal cells [nTPM]":"146.4","Single Cell Type RNA - Early spermatids [nTPM]":"1717.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"196.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"86.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"63.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.2","Single Cell Type RNA - granulocytes [nTPM]":"31.8","Single Cell Type RNA - Granulosa cells [nTPM]":"23.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"54.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"207.6","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"58.2","Single Cell Type RNA - Langerhans cells [nTPM]":"101.0","Single Cell Type RNA - Late spermatids [nTPM]":"4366.5","Single Cell Type RNA - Leydig cells [nTPM]":"50.1","Single Cell Type RNA - Macrophages [nTPM]":"118.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"38.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"223.4","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"54.2","Single Cell Type RNA - Plasma cells [nTPM]":"146.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"184.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"108.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"95.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"43.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.0","Single Cell Type RNA - Spermatocytes [nTPM]":"678.1","Single Cell Type RNA - Spermatogonia [nTPM]":"30.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"124.1","Single Cell Type RNA - T-cells [nTPM]":"27.3","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"57.5","Single Cell Type RNA - Urothelial cells [nTPM]":"239.8"},{"Gene":"PDXP","Gene synonym":["CIN","dJ37E16.5","FLJ32703"],"Ensembl":"ENSG00000241360","Gene description":"Pyridoxal phosphatase","Uniprot":["Q96GD0"],"Chromosome":"22","Position":"37658723-37666932","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"209.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"19.4","Inhibitory neurons":"25.0","Microglial cells":"7.5","Oligodendrocyte precursor cells":"8.0","Oligodendrocytes":"5.8","Plasma cells":"9.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"11.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"11.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000531"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000531":"AB_2666018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"23.7","Tissue RNA - amygdala [nTPM]":"144.7","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"158.7","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"106.1","Tissue RNA - cerebral cortex [nTPM]":"209.2","Tissue RNA - cervix [nTPM]":"6.7","Tissue RNA - choroid plexus [nTPM]":"83.0","Tissue RNA - colon [nTPM]":"20.6","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"26.3","Tissue RNA - hippocampal formation [nTPM]":"165.0","Tissue RNA - hypothalamus [nTPM]":"129.2","Tissue RNA - kidney [nTPM]":"15.9","Tissue RNA - liver [nTPM]":"74.5","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"117.5","Tissue RNA - midbrain [nTPM]":"130.0","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"9.5","Tissue RNA - pituitary gland [nTPM]":"39.6","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"119.8","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"29.6","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"15.8","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"32.2","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"109.2","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"27.0","Tissue RNA - thalamus [nTPM]":"137.8","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"148.0","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"19.6","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"12.0","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"18.9","Cell RNA - BJ hTERT+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.7","Cell RNA - CACO-2 [nTPM]":"9.9","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"54.0","Cell RNA - EFO-21 [nTPM]":"18.8","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"28.5","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"52.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"28.5","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"105.2","Cell RNA - HEL [nTPM]":"11.0","Cell RNA - HeLa [nTPM]":"26.6","Cell RNA - Hep G2 [nTPM]":"41.2","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"39.2","Cell RNA - HMC-1 [nTPM]":"47.0","Cell RNA - HSkMC [nTPM]":"1.8","Cell RNA - hTCEpi [nTPM]":"4.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.6","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"14.0","Cell RNA - HUVEC TERT2 [nTPM]":"15.6","Cell RNA - JURKAT [nTPM]":"61.1","Cell RNA - K-562 [nTPM]":"33.3","Cell RNA - Karpas-707 [nTPM]":"31.1","Cell RNA - LHCN-M2 [nTPM]":"29.9","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"74.3","Cell RNA - NB-4 [nTPM]":"61.3","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"15.2","Cell RNA - PC-3 [nTPM]":"46.4","Cell RNA - REH [nTPM]":"58.5","Cell RNA - RH-30 [nTPM]":"28.5","Cell RNA - RPMI-8226 [nTPM]":"39.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.6","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"89.5","Cell RNA - SH-SY5Y [nTPM]":"57.8","Cell RNA - SiHa [nTPM]":"17.8","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"36.1","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"31.8","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"28.7","Cell RNA - U-2 OS [nTPM]":"36.6","Cell RNA - U-2197 [nTPM]":"30.2","Cell RNA - U-251 MG [nTPM]":"37.6","Cell RNA - U-266\/70 [nTPM]":"33.0","Cell RNA - U-266\/84 [nTPM]":"44.1","Cell RNA - U-698 [nTPM]":"57.4","Cell RNA - U-87 MG [nTPM]":"27.2","Cell RNA - U-937 [nTPM]":"14.3","Cell RNA - WM-115 [nTPM]":"38.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"11.6","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"144.7","Brain RNA - basal ganglia [nTPM]":"158.7","Brain RNA - cerebellum [nTPM]":"106.1","Brain RNA - cerebral cortex [nTPM]":"209.2","Brain RNA - hippocampal formation [nTPM]":"165.0","Brain RNA - hypothalamus [nTPM]":"129.2","Brain RNA - medulla oblongata [nTPM]":"117.5","Brain RNA - midbrain [nTPM]":"130.0","Brain RNA - pons [nTPM]":"119.8","Brain RNA - spinal cord [nTPM]":"109.2","Brain RNA - thalamus [nTPM]":"137.8","Brain RNA - white matter [nTPM]":"148.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PHOSPHO2","Gene synonym":["MGC22679"],"Ensembl":"ENSG00000144362","Gene description":"Phosphatase, orphan 2","Uniprot":["Q8TCD6"],"Chromosome":"2","Position":"169694454-169701708","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"158.7","Spermatocytes":"68.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034726","HPA034727"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA034726":"AB_10602191","HPA034727":"AB_2674302"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"4.7","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"5.8","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"5.3","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"5.1","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"13.0","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"6.4","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"2.8","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"6.6","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"4.6","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"17.8","Cell RNA - BJ [nTPM]":"2.8","Cell RNA - BJ hTERT+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"4.9","Cell RNA - Daudi [nTPM]":"6.4","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"5.0","Cell RNA - HAP1 [nTPM]":"6.2","Cell RNA - HBEC3-KT [nTPM]":"3.4","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"9.5","Cell RNA - HEK 293 [nTPM]":"7.0","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"11.0","Cell RNA - HHSteC [nTPM]":"5.6","Cell RNA - HL-60 [nTPM]":"5.3","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.9","Cell RNA - hTERT-HME1 [nTPM]":"6.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"8.9","Cell RNA - K-562 [nTPM]":"10.8","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"2.7","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"3.6","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"5.1","Cell RNA - RPTEC TERT1 [nTPM]":"6.8","Cell RNA - RT4 [nTPM]":"19.6","Cell RNA - SCLC-21H [nTPM]":"19.1","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"5.8","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"2.3","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"6.0","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"6.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.6","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"158.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"35.9","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.3","Single Cell Type RNA - Spermatocytes [nTPM]":"68.9","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"5.5"},{"Gene":"PNPO","Gene synonym":["PDXPO"],"Ensembl":"ENSG00000108439","Gene description":"Pyridoxamine 5'-phosphate oxidase","Uniprot":["Q9NVS9"],"Chromosome":"17","Position":"47941506-47949308","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyridoxine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"88.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"62.6","Hepatocytes":"53.4","Proximal tubular cells":"86.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023204","HPA027776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023204":"AB_1855506","HPA027776":"AB_10601246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"15.8","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"22.0","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"10.7","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"21.9","Tissue RNA - kidney [nTPM]":"35.1","Tissue RNA - liver [nTPM]":"88.8","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"10.9","Tissue RNA - parathyroid gland [nTPM]":"26.6","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"16.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"37.9","Cell RNA - A549 [nTPM]":"30.9","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"5.8","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"11.7","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"12.2","Cell RNA - BJ hTERT+ [nTPM]":"7.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.9","Cell RNA - CACO-2 [nTPM]":"51.1","Cell RNA - CAPAN-2 [nTPM]":"27.6","Cell RNA - Daudi [nTPM]":"35.2","Cell RNA - EFO-21 [nTPM]":"57.4","Cell RNA - fHDF\/TERT166 [nTPM]":"12.7","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"34.7","Cell RNA - HBF TERT88 [nTPM]":"20.3","Cell RNA - HDLM-2 [nTPM]":"43.4","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"24.6","Cell RNA - HeLa [nTPM]":"13.9","Cell RNA - Hep G2 [nTPM]":"53.6","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"16.6","Cell RNA - HSkMC [nTPM]":"15.4","Cell RNA - hTCEpi [nTPM]":"26.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"32.7","Cell RNA - hTERT-RPE1 [nTPM]":"13.1","Cell RNA - HUVEC TERT2 [nTPM]":"18.0","Cell RNA - JURKAT [nTPM]":"26.1","Cell RNA - K-562 [nTPM]":"24.4","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"16.5","Cell RNA - MCF7 [nTPM]":"28.3","Cell RNA - MOLT-4 [nTPM]":"25.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"37.1","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"10.4","Cell RNA - RPMI-8226 [nTPM]":"26.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"9.5","Cell RNA - SiHa [nTPM]":"11.2","Cell RNA - SK-BR-3 [nTPM]":"18.6","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"8.5","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"12.8","Cell RNA - U-2197 [nTPM]":"22.2","Cell RNA - U-251 MG [nTPM]":"26.2","Cell RNA - U-266\/70 [nTPM]":"27.8","Cell RNA - U-266\/84 [nTPM]":"34.0","Cell RNA - U-698 [nTPM]":"19.0","Cell RNA - U-87 MG [nTPM]":"18.4","Cell RNA - U-937 [nTPM]":"19.2","Cell RNA - WM-115 [nTPM]":"11.7","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"7.2","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"13.5","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"11.9","Blood RNA - plasmacytoid DC [nTPM]":"9.8","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"10.3","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"22.0","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"21.9","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"16.5","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.9","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"6.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"62.6","Single Cell Type RNA - Ductal cells [nTPM]":"18.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"12.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"53.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"10.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"19.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"SH3BP1","Gene synonym":["ARHGAP43"],"Ensembl":"ENSG00000100092","Gene description":"SH3 domain binding protein 1","Uniprot":["Q9Y3L3"],"Chromosome":"22","Position":"37634654-37656117","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Phagocytosis"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"37.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"43.5","HMC-1":"45.4","NB-4":"44.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000757"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000757":"AB_1079951"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.39e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"14.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"19.4","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"37.7","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.5","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"27.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"27.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"5.7","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"10.5","Tissue RNA - vagina [nTPM]":"21.1","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"20.1","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"3.9","Cell RNA - AN3-CA [nTPM]":"3.4","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"28.6","Cell RNA - BJ [nTPM]":"3.8","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"5.9","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"12.6","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"43.5","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"26.0","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"36.9","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"18.5","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"8.6","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"25.9","Cell RNA - HMC-1 [nTPM]":"45.4","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"5.2","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"6.3","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"4.8","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"3.0","Cell RNA - NB-4 [nTPM]":"44.7","Cell RNA - NTERA-2 [nTPM]":"7.6","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"22.2","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"22.1","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"29.9","Cell RNA - U-266\/84 [nTPM]":"10.2","Cell RNA - U-698 [nTPM]":"9.0","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"26.4","Cell RNA - WM-115 [nTPM]":"13.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"4.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.5","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"23.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"8.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.5","Single Cell Type RNA - dendritic cells [nTPM]":"36.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"55.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.9","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.3","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"19.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"45.6","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"36.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.0","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"46.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"20.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.5","Single Cell Type RNA - T-cells [nTPM]":"52.7","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"42.0"}]