Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AASDH "ACSF4, LYS2, NRPS998" ENSG00000157426 "Aminoadipate-semialdehyde dehydrogenase" Q4L235 4 56338287-56387508 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036472, HPA036473" Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "HPA036472: AB_2675142, HPA036473: AB_10673656" "unprognostic (1.95e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (5.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-2)" "unprognostic (8.75e-2)" "unprognostic (1.29e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-3)" "unprognostic (1.59e-1)" "unprognostic (1.73e-1)" "unprognostic (4.52e-2)" "unprognostic (1.85e-3)" 4.3 4.9 3.9 4.7 4.6 4.5 8.4 6.1 4.2 5.8 4.0 4.5 4.5 6.4 8.1 4.6 7.0 4.4 3.7 3.6 4.2 6.7 6.5 4.5 6.4 4.5 4.5 8.4 3.8 7.2 4.2 5.0 4.6 6.4 5.8 11.8 5.6 5.4 4.2 7.1 4.2 5.7 4.1 5.9 4.7 5.0 4.3 6.2 7.1 4.2 6.7 4.3 4.3 5.3 5.0 3.3 8.6 6.6 12.8 14.7 5.3 6.2 7.5 6.3 5.4 3.8 10.2 10.9 5.7 6.8 4.8 3.1 6.3 6.3 7.0 4.4 6.3 5.1 6.3 4.9 11.4 9.4 3.7 8.5 10.2 6.7 10.0 9.1 9.8 6.9 11.9 5.4 7.2 4.9 11.1 7.8 4.8 9.1 4.8 8.2 4.2 5.1 9.0 4.2 5.7 5.5 7.1 11.2 7.2 8.1 8.9 6.0 6.7 4.2 5.6 4.4 4.5 4.3 3.6 7.1 6.6 8.4 4.6 0.0 2.0 1.6 2.8 2.5 3.7 2.4 2.8 2.4 2.2 3.0 4.0 3.0 0.4 2.8 1.6 1.9 2.9 1.3 3.9 4.6 6.1 4.2 3.6 4.2 4.5 4.5 4.6 4.1 4.3 5.3 14.1 6.4 16.2 59.4 17.3 10.1 13.9 26.0 13.6 38.7 21.7 21.2 10.1 14.3 17.3 18.4 27.1 40.7 22.8 9.4 25.4 9.9 26.0 22.0 28.6 13.9 12.1 24.0 26.9 7.6 19.4 17.9 14.8 21.0 20.3 26.4 19.6 21.9 15.4 35.3 36.7 14.7 22.4 17.6 8.7 5.2 16.8 12.6 10.6 19.7 21.5 31.3 20.6 36.2 39.1 6.0 13.4 18.0 9.9 14.2 8.0 29.2 11.2 56.4 6.6 22.5 11.9 43.3 35.0 13.6 15.6 23.9 16.5 23.8 15.9 8.1 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.5;Fibroblasts: 86.6;Inhibitory neurons: 73.2;Leydig cells: 96.3;Microglial cells: 227.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 21.8;ASC TERT1: 47.7;HSkMC: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" 33.7 4.1 2.8 1.4 5.1 1.8 22.3 7.7 8.0 14.7 6.3 12.4 1.8 11.2 8.9 4.8 20.6 8.2 22.6 3.0 1.4 2.7 11.9 8.8 2.3 3.1 1.2 27.4 3.5 2.3 4.9 1.2 4.5 3.3 4.0 8.4 9.0 2.8 13.1 9.2 6.6 6.6 1.2 1.6 7.8 5.2 3.5 2.5 11.1 10.6 1.1 10.9 12.7 7.7 0.2 0.4 0.8 0.8 21.8 47.7 0.6 0.4 0.4 0.0 0.4 0.5 0.5 0.6 0.2 0.8 0.3 0.5 0.4 0.7 0.2 0.3 0.4 0.6 2.4 0.6 2.3 0.9 1.3 17.0 0.5 3.6 0.3 0.9 4.8 0.6 0.8 1.3 0.1 0.3 0.3 2.1 0.3 0.2 0.4 2.2 0.1 0.3 0.3 1.9 0.7 0.6 0.5 0.3 0.3 0.4 0.4 0.8 2.0 1.3 0.5 2.3 0.5 1.0 0.5 0.4 0.4 0.5 2.4 0.5 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.0 0.1 0.0 0.0 2.8 5.1 7.7 8.0 3.0 1.4 3.1 1.2 4.5 1.2 3.5 7.7 7.4 0.0 1.5 2.6 0.5 1.8 0.3 0.1 1.2 3.9 0.7 0.8 3.9 1.5 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.1 1.3 0.4 2.1 2.6 0.0 0.0 55.5 0.0 0.0 86.6 2.0 1.4 0.0 2.2 18.5 11.4 0.3 0.0 73.2 0.1 0.0 1.3 5.1 3.6 96.3 4.9 0.0 227.7 0.0 7.9 1.0 6.0 10.9 0.2 0.0 15.4 0.2 0.1 0.3 0.0 1.7 5.6 13.1 26.3 7.1 1.3 0.8 1.3 1.6 0.0 0.5 26.3 0.1 0.3 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4;testis: 17.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.3;Inhibitory neurons: 41.7;Plasma cells: 92.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6;memory B-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "GAMG: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB033052: AB_2273463, HPA035113: AB_2674470, HPA035114: AB_10601329" "unprognostic (1.47e-2)" "unprognostic (6.46e-4)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (6.07e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (6.97e-2)" "unprognostic (1.70e-1)" "unprognostic (3.58e-3)" "unprognostic (2.71e-2)" 3.0 3.1 11.9 1.6 10.4 3.4 3.9 19.7 20.4 3.1 0.0 2.4 2.7 3.0 4.9 2.9 2.9 2.5 4.9 8.2 7.5 3.6 1.2 1.6 1.6 7.3 9.1 4.0 3.2 2.8 11.6 1.8 6.0 3.5 2.1 7.3 5.6 2.8 1.6 3.3 3.4 2.0 2.1 3.6 3.4 17.8 16.0 1.3 3.0 1.2 1.9 1.9 3.1 10.6 4.7 8.6 4.7 4.5 2.0 3.8 2.2 3.0 4.3 5.1 3.2 3.7 5.3 5.2 3.4 2.8 25.9 4.3 3.5 7.2 2.0 1.0 7.0 22.9 7.7 5.9 2.2 1.1 9.0 5.3 2.8 7.5 2.3 12.5 5.7 5.1 4.6 3.8 2.9 10.6 1.7 2.2 1.5 5.0 8.4 6.4 1.3 5.0 2.6 3.1 5.0 1.5 1.5 10.7 10.7 1.8 12.6 1.6 2.5 3.6 12.2 11.5 8.8 12.3 7.4 1.5 6.3 2.5 20.2 2.6 0.3 0.3 0.3 0.1 0.8 2.5 0.3 0.3 0.2 0.5 0.6 0.6 0.7 0.2 0.1 0.1 0.2 0.8 11.9 10.4 19.7 20.4 8.2 7.5 7.3 9.1 6.0 2.1 16.0 10.6 9.7 6.4 4.6 13.4 15.9 3.2 2.8 1.5 8.6 10.7 3.9 5.0 2.0 0.0 2.5 3.7 14.6 5.2 3.4 1.9 0.0 3.8 8.9 2.6 2.6 4.0 1.2 2.1 46.3 1.5 1.8 2.0 4.1 5.6 2.5 3.0 2.9 1.2 1.1 6.7 41.7 1.1 0.0 1.0 2.1 23.2 2.8 1.8 5.4 7.5 0.3 20.0 2.1 4.0 18.1 2.5 0.1 2.6 92.2 2.1 4.1 0.9 0.7 5.3 6.6 2.1 3.7 9.6 3.5 3.3 3.1 1.4 3.9 2.9 2.6 1.8 ABCC10 "EST182763, MRP7, SIMRP7" ENSG00000124574 "ATP binding cassette subfamily C member 10" Q5T3U5 6 43427366-43450427 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041607, HPA045464" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA041607: AB_2677579, HPA045464: AB_2679336" "unprognostic (2.41e-1)" "unprognostic (2.76e-1)" "unprognostic (1.85e-2)" "unprognostic (2.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (3.01e-3)" "unprognostic (1.85e-2)" "unprognostic (8.88e-2)" "unprognostic (2.64e-1)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.75e-1)" "unprognostic (3.85e-1)" "unprognostic (1.58e-1)" "unprognostic (2.80e-2)" 9.2 17.7 18.0 8.2 17.9 7.5 8.9 19.6 24.2 14.4 16.6 12.7 9.4 13.2 8.3 16.3 11.8 6.8 12.4 17.5 17.0 15.5 10.1 10.8 8.7 17.0 17.0 17.6 19.5 5.0 19.6 7.7 17.3 17.3 7.6 4.5 12.7 7.6 7.8 11.0 13.0 8.6 15.7 15.5 13.5 9.2 17.6 8.3 12.8 3.4 7.4 16.2 13.8 17.3 13.3 6.7 8.7 19.9 18.8 12.0 9.0 13.7 9.6 10.1 8.6 14.9 5.6 2.8 15.9 16.7 7.9 16.5 5.8 10.6 7.2 17.1 11.7 9.5 8.4 29.8 11.5 13.2 13.7 20.9 13.9 13.5 7.4 10.0 13.8 8.9 11.3 14.9 12.1 13.1 7.8 20.3 5.6 32.1 8.0 3.9 2.3 9.8 11.7 21.6 12.1 9.8 8.1 11.5 10.2 7.6 11.3 12.8 14.4 12.4 4.2 11.6 16.6 13.3 6.2 6.9 5.8 9.4 5.9 5.0 1.9 2.2 2.9 0.6 1.3 1.0 2.2 2.6 1.1 0.9 1.2 1.8 0.7 1.3 1.5 0.8 2.8 1.8 18.0 17.9 19.6 24.2 17.5 17.0 17.0 17.0 17.3 15.7 17.6 17.3 4.6 3.2 5.6 15.7 5.6 1.1 5.9 6.7 10.2 9.3 3.2 3.8 2.5 4.3 3.4 0.0 10.4 7.1 6.6 5.4 1.9 4.5 1.3 4.9 5.5 5.1 7.8 1.7 16.0 3.3 6.0 4.1 15.3 4.9 6.3 11.8 6.1 2.0 6.9 11.8 14.9 3.6 4.1 4.1 3.3 0.8 7.5 5.2 3.6 9.4 3.4 2.1 13.4 13.6 11.1 4.7 6.1 6.0 7.1 2.1 5.4 3.4 9.9 5.6 0.0 3.3 3.7 2.2 4.5 4.7 1.8 4.4 7.9 14.4 5.4 2.8 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476879 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pancreas: 20.1;pituitary gland: 34.4" "Group enriched" "Detected in some" 4 "Astrocytes: 19.6;Bipolar cells: 39.0;Endometrial stromal cells: 17.9;Enteroendocrine cells: 22.0;Excitatory neurons: 48.2;Inhibitory neurons: 39.3;Oligodendrocyte precursor cells: 39.2" "Cancer enriched" "Detected in some" 9 "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.8;AN3-CA: 1.4;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" No NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoli "Golgi apparatus, Cytosol" "CAB011451: , HPA042318: AB_2677947" "unprognostic (4.30e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-2)" "unprognostic (9.48e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.53e-3)" "unprognostic (6.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (2.22e-2)" "unprognostic (1.96e-2)" "unprognostic (6.88e-5)" "unprognostic (2.72e-2)" "unprognostic (1.85e-1)" 0.4 2.8 2.6 0.0 3.7 0.0 1.8 3.9 5.2 3.5 0.0 0.7 0.5 2.6 1.4 0.1 0.6 0.0 1.6 3.1 1.4 0.5 0.1 5.0 0.0 3.3 2.7 0.4 20.1 0.2 34.4 0.4 3.3 2.1 0.3 2.2 0.0 1.5 1.5 0.2 1.0 0.2 0.6 0.1 6.1 0.4 1.2 0.0 3.4 0.6 0.0 0.4 1.3 3.5 0.0 1.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.7 3.9 5.2 3.1 1.4 3.3 2.7 3.3 0.6 1.2 3.5 0.3 0.0 0.0 19.6 0.3 0.0 0.1 0.0 0.0 39.0 5.3 3.7 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.5 17.9 0.3 22.0 0.0 48.2 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 39.3 0.7 0.0 0.3 0.5 0.0 0.0 0.1 0.0 3.7 0.0 1.9 0.0 39.2 7.6 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.0 0.7 2.0 0.1 0.8 0.0 0.1 0.0 0.1 2.6 0.1 0.2 ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 19.5;Proximal enterocytes: 39.2;Syncytiotrophoblasts: 27.4" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 69.7;PC-3: 50.0;SK-BR-3: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" 14.6 33.3 3.1 5.4 3.9 4.7 12.5 3.4 3.8 7.5 2.2 14.7 10.6 33.2 1.7 3.7 9.3 3.4 11.9 2.9 3.4 7.0 13.3 7.6 3.9 4.4 3.6 5.4 11.9 2.1 10.0 4.7 4.8 9.9 1.8 0.5 6.2 5.6 20.5 4.4 17.4 4.8 3.1 13.8 7.2 19.0 5.5 4.3 6.0 4.6 1.7 11.9 6.1 4.2 13.2 4.0 2.6 11.2 7.4 3.2 34.3 6.3 6.8 4.2 7.4 2.6 7.1 3.5 69.7 8.6 11.3 1.7 1.6 1.4 0.5 11.8 2.1 10.3 42.1 34.1 9.8 6.4 22.4 6.2 1.7 4.8 0.4 4.4 6.7 4.7 6.0 12.4 5.9 4.7 4.5 6.1 3.3 3.2 50.0 7.8 6.2 5.7 3.2 1.4 2.8 11.5 16.4 49.2 26.4 3.0 3.7 10.8 7.9 5.5 7.4 14.3 7.0 12.2 5.7 8.4 6.9 21.7 7.8 0.4 3.2 2.5 0.8 3.0 4.0 1.0 1.0 1.2 2.7 0.7 1.1 0.8 1.7 0.7 2.8 1.7 0.3 2.5 3.1 3.9 3.4 3.8 2.9 3.4 4.4 3.6 4.8 3.1 5.5 4.2 5.0 0.0 1.1 3.6 3.8 3.2 1.6 1.6 0.6 2.2 2.7 2.8 2.4 2.8 2.2 3.7 2.1 12.2 4.8 9.5 0.0 3.8 0.7 2.0 3.5 3.4 6.0 3.6 0.5 6.9 19.5 4.5 3.6 4.0 0.0 6.9 5.7 6.8 12.6 8.4 0.9 5.0 2.0 15.9 8.4 2.7 4.1 12.3 1.8 0.0 5.9 2.4 0.0 0.0 1.2 5.0 2.1 5.7 2.4 0.8 39.2 2.8 1.2 0.7 6.6 2.3 2.8 3.8 4.8 0.8 1.3 27.4 4.0 7.8 5.5 1.4 ABCD4 "EST352188, P70R, PMP69, PXMP1L" ENSG00000119688 "ATP binding cassette subfamily D member 4" O14678 14 74285269-74303055 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003396 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "HPA003396: AB_1078078" "unprognostic (3.92e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-3)" "unprognostic (5.86e-2)" "unprognostic (3.69e-1)" "unprognostic (1.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.34e-2)" "unprognostic (3.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.21e-3)" "unprognostic (5.26e-2)" "unprognostic (2.35e-2)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (7.45e-3)" "unprognostic (7.93e-3)" 6.6 4.7 3.0 3.9 3.4 4.6 6.4 4.0 5.4 5.8 2.9 5.4 8.8 4.9 2.1 4.8 8.5 7.7 6.0 3.0 3.3 5.4 7.7 5.8 6.6 4.2 3.4 6.9 6.0 3.8 3.9 7.4 3.7 3.6 4.0 3.3 4.0 3.5 3.9 4.1 8.7 5.2 2.8 6.2 4.5 3.4 3.6 5.5 7.2 2.0 3.8 4.5 4.3 4.5 2.6 3.1 7.9 6.2 6.4 4.3 9.8 3.9 5.6 5.8 6.0 6.5 13.7 4.3 7.4 5.9 3.2 9.2 6.0 5.4 3.0 3.9 3.8 2.3 5.1 5.2 2.1 2.9 4.4 10.4 2.4 4.1 2.8 3.0 9.9 5.4 4.3 1.9 4.5 4.3 7.1 5.6 3.0 5.0 5.9 9.7 11.4 6.3 8.6 8.5 3.7 7.3 5.4 5.3 5.5 3.7 12.3 1.7 9.7 3.6 7.0 3.2 2.5 4.4 4.5 3.3 5.1 4.3 4.5 6.0 1.3 1.8 2.6 1.2 1.7 1.9 2.2 2.9 2.1 1.8 1.2 1.8 1.1 2.6 1.0 4.0 5.2 1.4 3.0 3.4 4.0 5.4 3.0 3.3 4.2 3.4 3.7 2.8 3.6 4.5 50.0 28.9 18.6 32.3 16.7 15.6 14.8 23.0 12.0 46.5 21.4 14.2 9.7 34.3 21.2 20.2 64.6 51.6 28.9 31.4 9.8 25.3 10.3 27.9 23.5 50.2 12.0 9.9 29.6 11.3 19.9 23.0 13.7 20.1 20.3 43.2 44.6 23.3 51.1 32.0 34.7 15.7 18.3 24.8 27.1 7.7 40.4 19.5 21.4 20.6 22.8 36.4 32.0 23.6 38.1 17.9 19.4 25.2 13.3 12.6 60.1 23.9 19.5 55.5 32.9 23.3 19.1 35.8 27.2 10.6 10.7 28.5 23.4 27.9 22.9 16.7 ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.6" "Group enriched" "Detected in many" 9 "Early spermatids: 295.1;Late spermatids: 1030.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.5;T-47d: 3.3;U-266/70: 3.0;U-266/84: 2.8" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" 1.2 0.6 0.8 0.1 0.7 0.0 0.5 1.5 1.1 0.1 0.3 0.1 0.0 0.3 0.4 0.1 0.2 0.2 0.5 0.7 0.8 0.3 3.3 0.1 0.2 0.9 0.7 0.4 0.1 0.4 0.2 0.0 0.9 0.7 0.0 0.4 1.5 0.2 1.9 0.0 0.1 0.3 0.9 0.1 0.2 21.6 0.9 0.0 0.4 1.7 0.1 0.0 0.0 0.9 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.2 3.0 2.8 0.0 0.1 0.1 0.1 0.0 0.2 0.8 0.6 0.0 0.2 0.5 0.3 0.3 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.7 1.5 1.1 0.7 0.8 0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.0 0.0 4.9 1.0 0.0 3.3 0.0 2.8 5.1 1.9 2.8 3.1 1.5 0.0 0.0 8.4 0.2 0.9 0.2 0.0 0.3 295.1 0.4 0.6 1.9 0.0 3.2 0.6 0.2 0.0 1.3 0.0 0.5 1.3 1.6 2.5 3.9 0.1 0.0 0.8 0.2 0.0 0.3 0.3 1030.5 6.5 1.2 0.0 1.9 0.5 8.1 3.1 2.0 2.2 0.0 0.0 5.7 0.5 3.6 0.2 3.0 0.7 4.9 0.0 2.4 1.2 70.5 3.9 0.3 0.3 0.0 1.8 0.3 0.2 2.2 ABHD16A "BAT5, D6S82E, NG26" ENSG00000204427 "Abhydrolase domain containing 16A, phospholipase" O95870 6 31686955-31703356 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 41.2;OE19: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058606 Approved NA NA 37000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "HPA058606: AB_2683774" "unprognostic (1.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.26e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (3.14e-1)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (6.17e-3)" "unprognostic (1.97e-3)" "unprognostic (6.02e-2)" "unprognostic (1.30e-2)" "unprognostic (9.35e-2)" "unprognostic (1.81e-1)" "unprognostic (5.11e-3)" "unprognostic (1.60e-3)" 16.2 22.1 1.1 11.7 1.3 6.7 13.3 1.2 4.1 20.5 0.9 20.9 0.0 21.5 19.0 21.1 18.9 9.9 17.4 1.2 1.2 17.0 30.0 16.0 13.0 1.6 2.0 15.0 18.7 5.8 40.0 7.9 1.4 19.6 7.3 6.7 17.4 4.2 35.0 12.9 17.6 0.0 1.5 18.5 21.5 31.6 1.5 4.5 21.3 0.0 0.0 20.7 15.0 1.5 0.0 15.7 0.0 41.2 29.0 11.7 0.0 14.5 16.2 16.5 15.6 0.0 26.1 16.5 33.7 21.2 0.0 0.0 0.0 19.7 9.0 16.0 12.7 0.0 0.0 0.0 34.7 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 42.4 0.0 0.7 0.0 29.3 21.0 0.0 0.2 20.0 0.9 0.5 0.4 0.0 0.0 0.0 14.9 19.6 14.5 0.0 0.0 10.5 21.1 8.5 13.6 0.1 16.1 2.5 6.8 8.4 4.1 8.9 1.9 2.8 1.2 4.2 6.2 2.8 3.5 2.7 13.3 5.9 0.5 4.1 4.1 6.3 1.1 1.3 1.2 4.1 1.2 1.2 1.6 2.0 1.4 1.5 1.5 1.5 1.2 0.0 8.2 11.4 10.7 0.4 0.3 1.7 15.4 1.2 1.5 1.0 0.5 0.0 1.6 0.0 0.0 3.9 2.2 12.0 3.9 18.3 1.3 1.4 1.7 2.7 12.5 14.9 13.4 13.3 1.5 5.3 12.2 1.2 1.3 0.5 0.7 0.8 3.3 0.0 14.6 9.7 2.0 2.2 2.1 0.4 0.9 8.8 3.6 13.1 8.1 1.0 5.2 15.6 21.1 12.7 16.0 0.4 16.4 0.4 16.5 0.7 1.7 1.4 0.0 0.7 4.9 2.5 1.6 16.8 1.0 5.3 7.6 0.2 12.1 0.3 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 AC002456.2 ENSG00000251154 "Uncharacterized LOC102723899" 7 90469639-90513397 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 69 "testis: 9.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.4;Basal respiratory cells: 3.0;Cholangiocytes: 2.8;Hepatocytes: 3.3;Melanocytes: 1.8;Spermatogonia: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Fibroblasts - ECM organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.4 3.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.1 0.6 0.8 1.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.5 1.3 0.8 2.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 AC010319.2 ENSG00000269035 "Novel protein" 19 17436611-17460804 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041580 Approved Uncertain "Nuclear membrane" NA NA "Nuclear membrane" "HPA041580: AB_10795700" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC010980.1 ENSG00000288658 "Novel protein, ortholog of Gm2102 (M. musculus)" 2 222317242-222320208 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.8;NB-4: 1.8;REH: 2.5;SCLC-21H: 3.7;SH-SY5Y: 1.7;SuSa: 1.7" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" 0.0 1.2 2.8 0.3 2.7 0.1 0.2 0.1 7.1 0.1 0.0 0.2 0.2 0.3 0.6 0.3 0.2 0.0 0.6 6.3 2.1 0.3 0.0 0.1 0.0 1.4 2.2 0.0 0.2 0.9 0.1 1.1 0.0 0.2 0.1 0.1 0.4 0.2 0.2 0.1 0.5 0.8 0.0 0.1 0.7 3.1 0.1 0.8 0.3 0.0 0.3 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 2.5 0.9 0.0 0.5 0.0 3.7 1.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.1 7.1 6.3 2.1 1.4 2.2 1.1 0.8 3.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC024592.3 ENSG00000267740 "Novel protein" 19 5866171-5903787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 3.1;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA072209 Uncertain Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.12e-2)" "unprognostic (2.24e-1)" "unprognostic (3.38e-1)" 1.1 1.9 0.8 0.2 0.8 1.0 1.0 0.8 1.5 1.1 1.1 1.6 0.8 0.9 0.2 2.2 0.6 0.6 2.6 0.9 0.9 1.3 2.4 1.0 0.3 0.9 1.0 1.1 1.0 0.2 1.0 0.3 1.1 1.1 0.0 0.3 1.1 0.2 2.3 1.2 1.0 0.6 0.9 1.1 1.1 0.7 1.0 0.6 0.8 1.2 0.4 1.2 1.4 0.9 3.5 4.6 1.4 3.9 2.7 0.5 1.2 2.3 3.2 4.3 3.0 1.7 2.9 2.9 2.2 1.8 2.0 2.4 0.9 2.7 0.8 1.2 1.4 0.7 1.8 3.9 1.8 1.3 1.5 1.1 4.5 3.3 1.5 1.3 1.4 4.1 1.2 3.7 0.6 2.9 4.8 1.0 2.2 1.5 2.2 4.5 1.4 3.7 2.0 1.1 2.3 3.2 1.7 2.3 2.5 0.6 1.4 4.3 2.8 0.8 2.1 5.3 4.6 3.4 4.1 1.6 2.7 4.6 1.9 4.4 4.8 2.3 3.2 4.3 2.8 4.2 3.4 3.1 5.0 4.0 3.8 3.1 2.7 3.6 3.9 6.2 4.4 8.1 0.8 0.8 0.8 1.5 0.9 0.9 0.9 1.0 1.1 0.9 1.0 0.9 0.1 3.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 AC068580.4 ENSG00000250644 "Novel protein" 11 1734821-1763954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "adrenal gland: 202.9;liver: 54.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.7;granulocytes: 1.3;Macrophages: 1.7;Respiratory ciliated cells: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 241.6;hTERT-RPE1: 212.9;U-87 MG: 63.6" HPA003001 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA003001: AB_1078404" "unprognostic (5.71e-2)" "unprognostic (1.79e-1)" "unprognostic (1.91e-6)" "unprognostic (1.77e-2)" "unprognostic (5.21e-2)" "unprognostic (6.20e-2)" "unprognostic (4.05e-3)" "unprognostic (1.45e-2)" "unprognostic (3.04e-1)" "unprognostic (1.14e-1)" "unprognostic (2.45e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-3)" "unprognostic (8.30e-4)" "unprognostic (7.35e-2)" "unprognostic (5.79e-5)" "unprognostic (7.47e-2)" 9.3 202.9 14.8 2.2 17.0 13.3 7.7 16.4 24.0 4.6 4.5 4.3 2.8 3.9 6.7 6.9 3.2 9.9 3.7 12.8 15.3 20.7 54.0 11.5 1.9 20.7 13.2 2.5 3.2 0.8 2.4 7.0 19.9 7.6 2.2 2.2 14.1 15.1 20.6 15.3 6.6 1.3 12.3 30.1 4.5 8.5 14.4 1.1 1.6 3.2 2.9 15.9 11.1 22.7 1.2 9.0 0.5 1.8 4.2 2.3 2.5 3.2 4.2 0.9 1.1 2.2 241.6 0.5 4.1 13.4 8.3 18.5 0.4 0.3 0.3 1.1 4.6 1.7 1.3 0.9 4.2 2.5 5.0 9.6 2.7 1.1 1.7 212.9 0.6 0.9 0.3 4.0 22.9 23.1 0.0 3.2 1.1 10.9 1.6 0.5 3.6 2.1 10.0 11.3 0.9 49.2 1.6 18.8 32.6 0.6 41.4 1.1 5.9 12.2 1.8 2.8 4.3 10.9 25.8 0.5 63.6 2.2 10.2 1.3 5.9 1.7 1.5 2.5 1.1 0.3 0.7 1.0 1.6 0.1 1.1 1.6 5.8 7.0 3.4 3.0 0.9 5.0 14.8 17.0 16.4 24.0 12.8 15.3 20.7 13.2 19.9 12.3 14.4 22.7 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 AC097637.1 ENSG00000173366 "Novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein" 3 52221081-52231190 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.8;lymphoid tissue: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "unprognostic (4.08e-2)" "unprognostic (9.63e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.7 0.1 1.8 0.0 0.0 2.6 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC117457.1 ENSG00000275163 "Potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)" 3 178419123-178843300 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 5.6;kidney: 1.5" "Group enriched" "Detected in some" 5 "Distal tubular cells: 1.9;Endometrial ciliated cells: 7.1;Proximal tubular cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HSkMC: 1.3" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.1 0.1 0.2 0.2 1.5 0.1 0.2 0.0 0.7 0.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.7 0.7 0.3 0.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC127029.3 ENSG00000285947 "Novel protein" 17 63917203-63931385 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 14.0;naive B-cell: 18.4" "Lineage enriched" "Detected in many" 5 "B-cells: 18.4" "Cell line enhanced" "Detected in single" "U-698: 2.2" "HPA009178, HPA043715" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA009178: AB_1078483, HPA043715: AB_2678632" 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.5 2.2 0.4 14.0 0.7 0.3 0.5 18.4 0.4 0.2 0.0 0.5 3.8 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC138894.1 ENSG00000261832 "Novel protein" 16 28456371-28492098 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 3.3;Distal tubular cells: 1.9;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053611 Uncertain Approved Nucleoplasm NA NA "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.93e-3)" "unprognostic (8.88e-3)" "unprognostic (4.33e-3)" "unprognostic (2.66e-1)" "unprognostic (3.59e-1)" "unprognostic (9.85e-2)" "unprognostic (3.82e-4)" "unprognostic (3.25e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (6.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (3.74e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.3 6.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.6 0.0 0.0 0.9 0.1 0.0 1.9 0.4 0.0 0.6 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.6 1.3 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 AC231657.3 ENSG00000288053 "Novel protein" X 49071470-49079887 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.3 0.4 0.3 0.2 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.4;placenta: 16.0" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.0;Extravillous trophoblasts: 106.2;Syncytiotrophoblasts: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.9;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.9;NK-cells: 1.1" "Cell line enhanced" "Detected in some" "BEWO: 51.2;HEL: 17.1;SK-BR-3: 28.0;U-937: 10.7" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 6.7 1.0 1.5 1.0 1.0 0.7 2.8 1.5 1.3 1.7 0.9 1.9 0.9 0.9 2.8 1.6 2.3 1.3 1.3 1.0 0.5 1.5 9.4 1.6 1.1 1.4 1.4 0.4 0.9 0.4 0.5 16.0 1.3 0.6 2.1 0.7 2.2 0.4 0.6 2.6 1.1 1.1 0.6 0.7 1.1 0.8 1.1 0.4 2.9 0.9 2.1 1.8 2.3 1.3 0.1 0.0 0.2 0.4 2.4 0.2 51.2 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.1 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 17.1 0.4 3.1 0.1 0.2 1.9 0.5 0.5 0.0 0.1 0.0 0.1 0.5 2.2 0.4 0.3 0.3 0.0 0.2 0.1 0.7 0.2 0.1 0.0 0.1 0.7 7.5 0.3 0.1 1.3 28.0 0.1 2.9 2.8 0.3 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.1 0.1 10.7 0.1 0.4 0.1 3.9 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.4 1.1 0.3 0.1 0.0 0.1 1.5 1.0 1.5 1.3 1.0 0.5 1.4 1.4 1.3 0.6 1.1 1.3 1.0 0.0 0.0 9.8 0.1 0.1 0.1 0.3 0.0 0.7 1.2 0.3 0.8 1.5 3.3 0.0 2.1 33.0 0.3 3.0 1.9 0.1 3.0 3.7 0.8 3.3 1.8 0.0 2.0 0.0 106.2 2.1 0.0 5.9 2.5 2.5 4.6 7.0 5.3 1.7 1.2 0.6 0.0 0.6 0.4 1.8 0.3 0.4 0.0 5.6 0.1 2.6 0.0 1.0 4.5 0.8 0.5 1.2 0.1 0.4 1.6 0.5 3.4 1.0 0.0 0.4 0.3 4.8 5.4 0.0 0.0 73.6 0.5 0.5 1.1 0.6 ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 142.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.8;Proximal enterocytes: 78.2;Proximal tubular cells: 128.4;Syncytiotrophoblasts: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 97.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" 24.8 71.9 7.6 5.7 8.5 3.3 21.0 7.7 10.1 18.9 8.6 26.9 22.1 6.7 15.8 7.7 9.7 10.8 25.9 7.1 7.0 142.1 36.4 17.8 8.5 8.5 7.3 19.3 6.8 9.9 2.9 15.4 8.0 15.0 17.5 1.1 15.8 16.0 41.3 22.5 20.2 5.4 8.2 8.4 18.8 4.9 7.9 5.6 42.5 25.8 8.2 17.8 13.4 7.7 24.8 8.1 6.6 15.8 68.1 12.1 38.1 5.9 8.6 12.6 24.5 32.1 47.2 15.7 12.6 7.3 11.5 14.7 4.7 29.2 15.3 19.5 11.2 27.3 3.9 58.5 11.4 3.3 24.3 54.9 44.4 15.8 2.1 45.4 17.4 20.3 3.2 8.8 13.7 31.3 8.8 11.1 1.1 47.5 11.9 20.6 4.8 41.2 4.2 97.2 21.6 11.3 11.8 17.3 12.3 13.7 15.5 22.8 12.7 22.5 6.8 3.5 1.9 15.4 3.1 8.2 9.3 17.1 1.4 0.0 2.9 15.3 2.0 7.7 1.7 8.6 1.5 2.1 16.1 2.0 0.7 0.9 0.5 1.6 7.0 6.3 5.5 2.7 7.6 8.5 7.7 10.1 7.1 7.0 8.5 7.3 8.0 8.2 7.9 7.7 3.2 28.9 24.3 27.1 7.3 6.0 23.3 17.0 25.0 0.0 20.8 16.0 25.9 11.5 19.9 3.7 0.0 85.8 1.7 59.5 11.7 13.5 0.4 4.9 3.5 4.9 10.2 1.3 0.3 4.3 11.7 6.5 21.9 7.7 22.2 24.5 4.2 44.4 21.9 0.0 0.3 20.6 2.0 9.8 11.0 1.6 26.8 11.0 3.6 17.8 12.7 6.1 5.2 3.5 0.5 5.7 53.1 14.3 2.6 3.5 78.2 128.4 14.6 0.2 0.0 2.7 5.9 0.2 2.2 5.4 7.0 81.0 4.1 12.1 25.8 14.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.3;Glandular and luminal cells: 208.8;granulocytes: 633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 16000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" 44.2 40.6 11.9 38.8 14.1 16.2 19.8 13.2 14.8 48.2 5.6 12.7 15.4 19.2 17.7 15.8 13.4 29.2 29.4 16.5 23.7 46.4 13.9 39.0 24.6 17.6 20.8 14.9 11.9 19.8 9.2 21.4 21.3 13.4 13.6 24.7 10.6 15.2 42.6 9.9 13.4 22.0 13.7 22.2 19.3 26.8 14.6 20.3 18.6 16.9 18.5 68.0 10.6 18.9 67.3 21.3 24.2 28.3 97.8 61.6 20.3 94.0 107.6 91.0 97.4 21.1 45.0 46.2 35.4 71.7 100.9 19.4 22.4 92.0 143.0 15.7 23.3 181.4 26.6 223.3 44.8 44.8 360.0 51.4 36.7 103.6 74.0 50.2 71.8 25.5 5.6 54.2 100.7 4.7 40.7 60.7 31.6 15.2 37.2 26.4 45.4 39.6 136.3 20.9 15.2 12.3 109.3 0.4 63.2 49.0 1.9 45.8 128.5 81.1 22.6 129.3 85.9 28.1 31.7 41.2 139.7 97.8 52.2 32.5 10.9 35.0 4.2 15.5 3.2 3.3 3.9 3.5 10.6 3.1 3.0 3.8 29.6 4.0 19.4 4.0 6.7 6.5 11.9 14.1 13.2 14.8 16.5 23.7 17.6 20.8 21.3 13.7 14.6 18.9 27.9 76.9 184.3 29.0 19.5 22.3 25.7 20.0 81.4 44.2 7.3 8.1 37.2 15.7 40.1 73.5 2.1 7.3 18.3 0.8 50.9 27.7 1.4 79.5 27.0 29.8 7.7 26.1 76.7 25.4 36.9 46.0 7.1 208.8 633.8 151.6 18.2 44.2 23.9 6.7 78.3 5.7 2.0 64.9 59.1 4.9 5.6 67.8 16.0 57.1 70.4 10.9 8.2 71.4 116.4 32.3 3.0 10.1 36.1 19.4 0.7 12.4 12.2 16.7 0.0 20.0 27.9 3.7 5.3 10.1 8.1 31.6 25.2 34.9 2.7 18.4 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ACSM1 "BUCS1, MACS1" ENSG00000166743 "Acyl-CoA synthetase medium chain family member 1" Q08AH1 16 20623237-20698890 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "breast: 225.3" "Cell type enhanced" "Detected in many" "Early spermatids: 13.2;Late spermatids: 23.2;Theca cells: 8.4" "Group enriched" "Detected in many" 8 "liver cancer: 14.7;prostate cancer: 36.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "NTERA-2: 15.6" "Not detected" "Not detected" HPA046291 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 25: Spermatids - Spermatogenesis" "HPA046291: AB_10960704" "unprognostic (1.08e-2)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (5.49e-4)" "unprognostic (1.66e-1)" "unprognostic (3.50e-2)" "unprognostic (9.46e-2)" "unprognostic (3.10e-1)" "unprognostic (8.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.64e-1)" "unprognostic (8.24e-2)" "unprognostic (3.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 0.4 0.5 0.3 0.0 0.4 3.6 225.3 0.4 0.4 2.0 0.2 1.0 0.5 2.1 0.4 0.4 2.2 0.4 0.5 0.3 0.4 1.1 10.7 0.5 0.3 0.4 0.3 2.5 1.6 0.9 0.1 0.0 0.5 3.7 0.6 0.1 1.8 0.6 0.3 2.0 0.7 0.8 0.3 0.5 2.2 4.4 0.4 0.4 0.5 0.2 0.2 1.0 1.4 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.1 15.6 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.4 0.4 0.1 0.0 0.0 0.3 1.0 0.6 2.6 1.2 1.2 0.0 2.5 2.4 1.0 5.7 1.4 0.0 0.0 0.2 0.2 1.6 1.9 4.2 13.2 1.4 0.2 1.5 1.2 1.3 0.8 2.3 0.1 0.7 2.0 0.8 0.0 2.8 3.6 1.3 0.2 0.0 0.7 2.9 0.0 0.3 2.8 23.2 4.4 0.6 0.0 0.0 1.7 0.0 0.0 1.0 1.3 1.2 3.7 7.2 0.0 2.5 0.6 1.4 3.7 0.0 0.0 0.1 0.2 0.8 0.2 1.1 1.6 0.1 0.3 8.4 2.5 1.4 ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487669 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1182 "kidney: 277.2;liver: 363.3" "Group enriched" "Detected in some" 17 "Hepatocytes: 708.7;Proximal tubular cells: 372.5" "Group enriched" "Detected in some" 479 "liver cancer: 22.7;renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Hep G2: 1.9" HPA057699 Supported NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA057699: AB_2683506" "unprognostic (1.17e-4)" "prognostic favorable (1.41e-5)" "unprognostic (5.25e-1)" "unprognostic (2.42e-1)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (5.10e-1)" "unprognostic (2.09e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 277.2 363.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.0 4.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 21.5 0.0 7.3 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.0 0.0 2.7 0.0 13.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.2 708.7 0.0 0.0 0.2 0.0 0.0 18.3 0.0 0.2 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 372.5 0.0 0.0 0.0 0.5 0.1 0.2 0.1 0.0 0.1 0.3 1.7 0.0 0.0 0.1 ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 173 "kidney: 414.1;liver: 523.5" "Group enriched" "Detected in some" 20 "Hepatocytes: 1036.1;Proximal tubular cells: 441.9" "Group enriched" "Detected in some" 449 "liver cancer: 30.9;renal cancer: 17.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;Hep G2: 5.5;U-937: 1.9" HPA057699 Supported NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA057699: AB_2683506" "unprognostic (1.34e-2)" "prognostic favorable (3.31e-4)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (6.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" 0.4 0.5 0.4 0.0 1.0 0.2 0.3 2.7 1.6 0.1 0.1 0.8 0.3 0.3 0.3 0.3 0.4 0.5 0.6 0.6 0.8 414.1 523.5 0.4 0.2 0.7 0.5 0.4 0.2 0.2 0.1 0.1 0.7 0.2 0.0 0.5 0.1 0.0 0.9 0.8 0.1 0.1 0.1 0.3 0.6 0.9 0.4 0.1 1.0 0.0 0.1 0.0 0.1 0.8 0.5 0.0 2.9 0.7 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.7 0.5 0.0 1.4 0.0 0.4 0.4 0.0 0.0 0.0 0.5 0.4 0.1 0.7 5.5 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.5 0.0 0.0 0.4 0.3 0.5 0.6 0.7 0.0 0.0 0.6 0.1 0.0 0.1 0.9 0.5 1.4 0.0 0.5 0.1 1.1 0.2 0.0 0.0 0.5 0.0 0.4 0.3 0.2 0.3 0.2 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.0 2.7 1.6 0.6 0.8 0.7 0.5 0.7 0.1 0.4 0.8 0.5 0.0 0.0 0.0 6.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 28.6 0.0 7.3 0.0 0.0 0.0 0.2 35.2 0.1 0.8 0.0 0.0 2.2 1.8 24.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.7 1036.1 0.1 0.0 0.0 0.0 0.0 23.2 0.4 0.7 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 441.9 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 2.7 0.1 0.0 0.0 ACSM4 ENSG00000215009 "Acyl-CoA synthetase medium chain family member 4" P0C7M7 12 7304284-7328724 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Excitatory neurons: 1.2;Inhibitory neurons: 1.1;Spermatogonia: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.7;Karpas-707: 1.1;NB-4: 1.8;SH-SY5Y: 2.0;U-87 MG: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA049895 Uncertain NA NA "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA049895: AB_2680940" "unprognostic (9.50e-5)" "unprognostic (5.45e-2)" "unprognostic (4.84e-2)" "unprognostic (6.06e-4)" "unprognostic (1.77e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-3)" "unprognostic (3.31e-3)" "unprognostic (3.85e-2)" "unprognostic (8.78e-2)" "unprognostic (3.27e-1)" "unprognostic (3.60e-1)" "unprognostic (2.45e-9)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.73e-1)" 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 2.0 0.3 0.5 0.0 0.0 0.0 0.6 0.4 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.7 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228928 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.6;pancreas: 4.0;skin 1: 1.9;stomach 1: 1.9;urinary bladder: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Cone photoreceptor cells: 2.1;Early spermatids: 2.4;Excitatory neurons: 3.8;Inhibitory neurons: 3.4;Oligodendrocytes: 2.1;Rod photoreceptor cells: 5.3" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "RT4: 3.7" HPA044593 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.71e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.9 0.1 0.1 3.6 0.4 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 2.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.4 0.6 1.2 0.6 0.0 0.0 3.8 0.0 0.0 0.1 1.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 ACSS1 "ACAS2L, AceCS2L, dJ568C11.3, MGC33843" ENSG00000154930 "Acyl-CoA synthetase short chain family member 1" Q9NUB1 20 25006230-25058980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 300.4;Cytotrophoblasts: 329.7;Syncytiotrophoblasts: 419.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 50.3;JURKAT: 51.2;MOLT-4: 49.6;OE19: 64.6;RPMI-8226: 75.1;U-937: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041014, HPA043228" Enhanced NA NA "Cluster 15: NK-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA041014: AB_2677251, HPA043228: AB_2678372" "unprognostic (6.87e-2)" "prognostic favorable (9.37e-4)" "unprognostic (5.32e-2)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.03e-2)" "unprognostic (3.20e-3)" "prognostic favorable (8.33e-5)" "unprognostic (2.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.43e-1)" "unprognostic (7.72e-2)" "unprognostic (4.58e-3)" "unprognostic (5.85e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (1.60e-1)" 12.8 9.5 65.0 15.5 70.2 33.4 14.1 55.8 66.9 16.1 124.7 28.1 49.3 16.1 19.7 14.3 18.8 15.0 91.3 64.5 55.7 49.9 13.9 20.2 25.5 57.9 65.0 22.6 57.4 34.0 11.3 118.4 53.8 29.1 20.6 4.0 39.8 12.0 44.6 18.0 46.8 13.1 53.4 33.6 62.9 38.6 67.7 30.9 29.8 41.4 21.3 15.7 14.5 60.8 0.1 11.8 3.4 0.0 10.6 4.0 0.2 1.3 5.1 5.0 3.3 12.0 1.6 21.0 2.0 4.8 21.5 5.9 17.1 2.6 1.0 0.0 1.6 36.0 0.2 50.3 11.1 8.5 0.4 7.0 8.6 0.5 0.0 0.0 10.9 51.2 1.9 39.0 0.4 1.3 49.6 14.6 0.2 64.6 18.9 38.2 1.1 75.1 7.3 9.4 8.3 0.2 2.3 4.6 33.5 0.2 22.5 19.1 1.7 0.1 0.1 0.1 0.6 26.7 1.9 0.0 0.5 51.5 13.0 5.6 2.8 7.2 4.2 5.1 3.3 4.0 2.7 3.6 3.5 5.1 2.3 3.5 0.5 10.2 3.4 2.1 2.7 2.3 65.0 70.2 55.8 66.9 64.5 55.7 57.9 65.0 53.8 53.4 67.7 60.8 10.8 12.8 15.1 300.4 29.8 5.2 6.7 3.1 5.2 2.2 15.1 8.0 73.0 45.8 7.7 11.0 0.0 329.7 26.4 27.2 76.3 6.5 87.7 14.3 5.0 9.7 0.0 42.9 0.9 7.7 10.9 14.0 26.5 7.2 5.7 20.4 9.3 6.2 53.2 0.0 1.8 28.5 10.2 11.2 8.8 16.2 34.5 12.0 7.2 41.2 12.3 14.8 25.7 32.2 31.4 1.9 15.8 32.4 42.2 14.0 90.6 16.7 13.8 1.0 19.7 8.8 12.0 1.1 2.0 9.5 4.3 419.5 22.6 60.2 23.4 4.1 ADAM20 ENSG00000134007 "ADAM metallopeptidase domain 20" O43506 14 70522358-70535015 "Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.6;testis: 5.1" "Cell type enhanced" "Detected in some" "Astrocytes: 30.0;Early spermatids: 55.5;Excitatory neurons: 45.4;Inhibitory neurons: 37.4;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 23.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059377 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA059377: AB_2683997" "unprognostic (4.13e-3)" "unprognostic (3.45e-2)" "unprognostic (1.14e-1)" "unprognostic (8.34e-2)" "unprognostic (2.06e-1)" "unprognostic (1.57e-2)" "unprognostic (5.61e-2)" "unprognostic (2.89e-2)" "unprognostic (1.58e-3)" "unprognostic (1.77e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.46e-3)" "unprognostic (2.64e-1)" "unprognostic (6.83e-2)" "unprognostic (5.06e-2)" "unprognostic (9.52e-3)" 0.1 0.0 0.8 0.0 0.6 0.0 0.1 1.6 1.3 0.2 0.5 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.5 0.1 0.1 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 1.6 1.3 0.5 0.5 0.2 0.3 0.1 0.0 0.5 0.5 0.2 0.0 0.0 30.0 0.0 0.3 0.1 0.1 0.0 4.1 0.3 0.3 0.5 0.0 0.1 0.0 4.2 0.1 0.3 0.2 0.0 0.3 55.5 0.2 0.2 0.4 0.0 0.0 45.4 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 3.3 37.4 0.0 0.0 0.0 0.0 8.2 0.3 0.1 0.0 12.2 0.1 0.3 0.0 23.1 23.9 0.2 0.0 0.7 0.1 0.5 0.0 0.0 0.4 3.5 0.0 0.5 0.3 5.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.6 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1795.3;Excitatory neurons: 3843.1;Inhibitory neurons: 2738.1;Oligodendrocyte precursor cells: 2036.3;Oligodendrocytes: 1210.5" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.8;SH-SY5Y: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" 0.8 3.9 21.1 0.8 25.5 0.0 0.6 49.6 29.7 1.3 0.0 4.3 0.4 2.2 0.9 0.7 0.9 0.9 1.9 31.1 12.1 1.0 0.5 1.7 0.0 0.0 0.6 1.6 0.3 0.1 23.7 0.1 1.1 1.0 1.3 7.1 1.2 1.4 0.3 0.4 1.4 3.3 0.0 0.6 1.3 1.9 18.2 0.1 0.8 1.4 0.0 2.6 1.4 19.1 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.0 1.2 1.0 0.0 0.0 8.8 19.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 21.1 25.5 49.6 29.7 31.1 12.1 0.0 0.6 1.1 0.0 18.2 19.1 3.1 0.0 0.0 1795.3 0.3 0.0 0.1 0.0 0.0 47.3 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.2 4.8 0.6 0.0 0.0 3843.1 0.0 0.0 2.1 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 2738.1 0.0 0.0 0.6 0.0 3.1 5.0 1.3 0.0 216.4 1.0 0.8 0.0 2036.3 1210.5 0.1 0.0 8.6 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.6 7.4 11.8 3.2 0.2 0.0 0.0 0.0 0.5 0.0 0.1 ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Excitatory neurons: 902.7;Inhibitory neurons: 646.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 252.8;hTEC/SVTERT24-B: 130.3;NTERA-2: 100.0;SH-SY5Y: 168.3;U-2197: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" 19.8 19.9 11.0 8.2 13.4 0.0 17.8 6.5 26.3 16.4 5.0 15.3 5.8 12.4 15.0 23.6 23.1 23.1 28.5 13.9 14.6 21.4 38.5 64.9 8.9 8.6 10.7 36.3 9.7 27.5 20.5 48.8 7.6 30.0 10.9 25.2 36.7 19.4 4.4 12.9 13.4 12.7 7.0 19.9 15.5 4.2 15.5 10.4 43.2 19.7 8.7 13.2 23.4 15.0 18.2 9.9 252.8 0.0 30.3 35.3 3.4 6.4 14.8 2.5 2.9 0.0 0.0 0.1 69.6 34.6 7.1 10.1 20.3 28.0 2.3 0.5 41.5 0.0 7.0 16.6 11.8 0.0 0.4 32.5 1.8 130.3 12.9 17.8 42.9 0.0 0.0 0.0 3.4 0.2 0.0 0.1 100.0 0.0 7.1 0.0 34.9 0.0 56.9 3.8 11.7 168.3 0.0 6.3 0.0 73.5 0.4 74.7 27.5 26.0 28.9 118.9 9.3 0.0 0.0 0.2 14.9 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 13.4 6.5 26.3 13.9 14.6 8.6 10.7 7.6 7.0 15.5 15.0 25.3 3.2 2.2 23.8 0.2 0.0 7.0 0.0 2.2 48.5 6.6 11.2 44.1 10.0 3.1 5.5 6.2 0.4 0.1 2.1 0.0 4.7 1.4 11.7 10.3 36.9 0.0 0.0 902.7 1.6 0.4 19.6 0.5 25.4 0.0 32.3 30.0 39.3 0.9 33.7 646.8 2.0 0.0 3.1 0.0 1.4 23.3 1.1 0.0 69.3 0.0 19.0 0.0 11.1 13.0 0.8 3.6 17.7 0.0 10.4 0.0 7.8 0.0 3.9 19.7 2.5 19.8 1.5 3.5 4.1 0.0 0.4 0.5 43.1 3.5 3.0 ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940826-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 329.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (5.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (5.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.84e-1)" "unprognostic (8.63e-2)" 59.8 58.5 56.1 49.1 60.1 215.2 63.6 58.7 64.2 55.4 82.9 55.6 46.5 40.9 91.4 110.9 68.6 48.2 92.6 56.8 57.7 70.4 106.2 80.5 48.0 61.2 58.6 47.7 91.7 107.1 45.5 100.0 60.2 53.7 59.8 135.6 106.6 47.4 136.5 110.8 47.4 50.9 60.1 65.8 63.3 48.7 58.7 50.2 56.6 140.2 77.9 70.9 69.2 65.2 97.0 87.2 53.4 59.9 111.4 85.4 276.8 103.4 123.9 108.8 99.4 88.7 114.7 63.5 75.3 120.6 86.3 118.0 81.3 145.5 96.5 118.5 93.5 48.6 104.3 72.6 109.7 101.6 71.6 101.7 235.0 115.9 118.3 108.4 108.8 111.7 128.1 133.5 111.2 105.6 85.3 77.4 119.7 87.1 103.1 66.7 128.7 125.7 106.5 111.0 89.2 90.8 109.6 166.5 135.5 143.6 121.1 99.4 95.7 78.9 62.2 39.4 117.3 137.8 197.4 71.4 113.5 58.9 94.5 362.2 361.8 455.4 136.0 253.6 143.8 157.9 143.4 134.1 209.8 165.2 141.5 124.3 825.9 126.0 259.6 146.1 179.5 557.4 56.1 60.1 58.7 64.2 56.8 57.7 61.2 58.6 60.2 60.1 58.7 65.2 40.7 35.3 52.5 6.8 46.8 235.0 95.2 109.8 75.7 24.8 81.9 54.2 59.7 32.9 79.3 53.3 29.2 112.7 42.8 49.3 68.4 73.8 68.2 58.8 24.5 53.4 49.1 329.0 13.7 86.3 172.4 40.9 37.2 54.3 37.3 18.8 58.5 60.8 104.2 11.8 15.1 49.1 85.5 148.5 89.7 62.5 28.6 107.6 85.4 15.9 85.0 38.0 42.2 9.5 20.0 120.0 43.5 24.5 116.0 133.1 67.3 65.9 82.5 54.9 39.5 29.2 61.7 26.4 27.2 79.3 228.9 202.8 47.1 29.2 41.7 206.6 ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;brain: 101.4;lymphoid tissue: 54.1" "Group enriched" "Detected in some" 6 "B-cells: 5.8;monocytes: 10.9;Plasma cells: 11.8;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 101.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 39.3;Karpas-707: 52.8;RPMI-8226: 41.1;SK-BR-3: 74.0;U-266/70: 52.8;U-266/84: 74.4;U-698: 55.0" "Region enriched" "Detected in many" 9 "basal ganglia: 399.8" "Region enriched" "Detected in many" 50 "basal ganglia: 142.2" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" 3.4 5.4 12.3 13.5 101.4 40.6 2.5 10.8 19.2 4.0 8.0 4.1 6.6 2.9 1.6 2.0 3.7 3.0 13.5 11.6 10.0 17.5 14.5 14.6 20.5 10.2 10.4 3.9 2.3 0.2 6.7 1.8 10.4 5.5 1.0 2.1 3.2 1.7 2.5 1.6 7.0 0.9 9.9 15.2 4.0 3.1 19.9 54.1 4.3 1.4 10.4 5.3 3.4 9.7 0.5 0.9 1.0 0.3 0.4 0.3 1.0 0.7 23.2 1.3 2.4 4.5 0.3 39.3 2.6 0.7 2.4 1.0 2.4 0.0 0.0 4.7 6.6 0.7 0.2 5.6 0.4 0.8 18.7 0.2 0.2 7.2 0.0 0.5 8.2 5.8 0.3 52.8 0.0 0.7 14.0 4.2 1.6 5.0 0.1 0.6 1.7 41.1 0.1 0.3 3.9 21.6 1.1 74.0 0.3 1.1 0.8 3.7 0.5 2.2 3.7 0.5 0.4 52.8 74.4 55.0 11.5 13.6 0.3 9.6 2.1 11.6 20.0 6.5 46.9 21.9 37.4 39.2 2.6 38.3 51.5 42.4 32.6 6.3 23.1 2.9 54.0 27.1 12.3 101.4 10.8 19.2 11.6 10.0 10.2 10.4 10.4 9.9 19.9 9.7 0.0 0.0 0.5 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.5 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 98.5;parathyroid gland: 92.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.4;Distal tubular cells: 52.8;Early spermatids: 141.6;Late spermatids: 168.0;Paneth cells: 87.0;Proximal enterocytes: 127.0;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.5" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 93.9;RPMI-8226: 41.2;TIME: 57.7;U-138 MG: 42.4;U-266/84: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" 0.5 0.2 1.9 14.2 2.1 1.1 3.3 0.6 2.2 0.4 35.2 80.7 82.4 0.3 13.7 1.5 0.6 1.6 0.3 2.0 0.0 9.8 1.4 11.1 9.4 0.1 0.1 0.2 0.8 92.9 0.0 2.4 0.1 0.4 58.5 0.6 0.8 24.4 1.0 18.9 98.5 2.6 0.1 1.3 38.2 22.6 0.4 2.6 0.5 0.1 12.7 10.2 0.3 1.1 4.1 0.0 0.0 0.0 0.5 0.9 0.1 1.5 0.8 1.0 0.7 3.6 1.9 0.1 1.7 0.7 2.4 1.9 0.0 11.2 1.4 0.1 0.0 0.3 0.8 0.1 0.3 0.1 0.2 0.0 20.4 10.4 23.6 17.5 93.9 0.7 23.0 0.0 3.1 0.1 0.2 0.6 0.3 0.1 5.8 0.0 0.3 41.2 1.7 0.2 0.1 0.2 1.5 0.0 0.8 2.8 0.0 0.8 57.7 42.4 2.0 0.7 2.6 1.2 47.1 0.0 7.9 1.3 0.2 2.7 0.0 0.0 0.0 0.3 2.6 0.2 3.7 0.3 0.1 0.2 14.8 1.3 0.3 0.1 0.2 0.2 13.5 1.7 1.9 2.1 0.6 2.2 2.0 0.0 0.1 0.1 0.1 0.1 0.4 1.1 0.2 0.0 1.1 0.7 4.0 5.1 0.3 3.9 0.6 0.0 0.1 1.9 0.1 0.0 2.6 5.5 0.0 0.2 0.1 116.4 52.8 0.7 141.6 0.2 0.0 0.3 5.4 2.7 13.1 2.4 0.2 1.1 32.1 0.1 5.7 0.0 0.0 0.2 11.4 0.0 0.4 40.7 2.0 0.8 1.5 168.0 1.8 3.1 1.8 0.0 27.9 0.0 1.0 1.0 0.1 7.9 87.0 0.7 7.8 0.6 127.0 0.7 0.8 0.0 0.0 0.2 1.2 1.6 0.7 0.4 5.7 0.1 6.2 0.0 52.3 0.5 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 91.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 47.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: AB_2680411, HPA073355: AB_2686596" "prognostic unfavorable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 46.6 60.3 3.0 5.9 7.2 6.6 42.6 2.5 47.1 58.2 2.9 61.3 28.2 64.3 42.9 33.9 56.5 18.9 66.9 4.0 25.5 61.6 60.2 44.2 10.9 3.8 9.5 67.2 37.5 9.3 53.8 15.9 4.4 53.2 20.1 12.5 34.1 0.0 67.7 35.1 53.0 1.5 2.5 39.8 58.4 79.3 3.3 18.4 54.1 33.5 12.5 58.2 42.7 4.7 0.0 0.4 51.2 0.3 127.5 85.2 49.4 0.0 0.0 0.0 0.0 104.5 0.0 0.0 46.1 128.0 36.4 13.4 108.5 39.4 0.0 0.4 83.6 0.0 0.0 111.7 0.0 0.0 101.5 51.0 47.6 0.0 46.0 105.9 31.6 86.7 78.5 66.0 109.2 28.8 0.4 26.8 0.0 0.1 18.0 0.6 0.0 0.5 32.8 0.0 0.0 0.1 51.3 16.1 70.4 51.6 63.4 0.0 25.9 0.0 20.3 0.0 0.2 45.9 41.1 18.0 64.3 0.1 0.3 3.4 5.6 12.4 7.6 8.2 7.4 5.3 5.0 8.6 9.3 5.0 4.3 6.4 9.4 8.7 5.8 11.6 7.2 6.9 3.0 7.2 2.5 47.1 4.0 25.5 3.8 9.5 4.4 2.5 3.3 4.7 32.1 16.0 18.6 11.1 14.3 9.1 14.0 20.6 16.5 26.1 26.2 21.6 4.0 14.3 12.0 36.8 12.5 35.2 24.5 28.7 5.9 17.9 63.9 14.1 24.9 21.3 29.4 12.0 13.8 14.3 29.9 19.6 16.3 11.4 12.7 22.7 27.1 31.2 24.7 32.0 17.7 24.3 18.3 22.3 20.6 91.7 13.4 24.9 8.8 11.2 13.0 38.5 21.6 10.1 14.8 17.0 22.3 21.4 16.9 10.2 73.6 29.4 12.9 17.9 0.0 18.3 22.9 44.8 22.1 9.5 3.7 15.3 13.8 21.5 20.8 12.1 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 369.3;liver: 445.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 688.9;Late spermatids: 387.3;Paneth cells: 670.7;Proximal enterocytes: 1298.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 186.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019544 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 369.3 38.3 11.4 11.8 9.3 34.2 259.9 8.8 15.9 32.1 13.5 83.2 111.4 26.4 9.6 85.6 29.7 15.7 84.9 9.4 12.6 80.2 445.0 60.9 9.2 11.8 12.3 17.7 129.6 18.4 41.5 8.0 11.3 34.3 12.2 0.9 48.1 12.8 37.4 51.1 119.4 6.7 11.4 39.2 52.0 24.1 13.9 5.5 46.9 10.0 5.3 35.5 36.6 9.6 55.0 75.2 8.9 41.4 63.3 19.8 37.3 35.5 28.5 24.1 18.5 86.0 105.7 17.8 77.8 21.0 38.6 145.1 12.7 22.2 2.8 186.9 57.3 26.5 30.3 19.2 42.6 28.1 62.1 19.0 30.9 20.9 11.0 20.9 12.5 23.6 32.7 2.9 10.4 98.5 1.9 87.4 22.5 101.0 135.0 41.0 31.3 100.3 28.5 33.9 19.5 31.4 45.8 47.6 60.3 6.8 30.6 109.3 24.7 31.5 32.1 10.4 23.0 4.4 0.4 11.8 0.4 59.7 32.1 20.1 88.8 111.8 6.8 83.5 6.5 12.8 5.8 7.9 47.8 22.7 4.6 5.5 61.1 7.2 75.7 65.6 8.1 35.2 11.4 9.3 8.8 15.9 9.4 12.6 11.8 12.3 11.3 11.4 13.9 9.6 25.9 16.0 64.4 0.7 20.2 45.2 60.0 64.0 22.8 3.5 23.4 22.4 39.6 87.2 45.3 73.5 0.0 7.3 30.8 688.9 54.8 155.2 136.4 50.4 17.4 27.9 35.8 8.0 1.9 219.5 37.1 30.1 81.6 63.8 13.4 31.4 31.1 228.0 131.2 40.4 2.6 197.3 126.1 53.4 57.4 387.3 26.8 57.6 136.9 4.7 48.8 14.6 23.7 0.0 0.3 169.5 670.7 20.3 13.4 93.5 1298.3 41.9 46.3 3.8 46.0 15.3 29.8 1.8 27.2 47.5 81.3 6.8 26.6 16.4 207.7 196.2 AGPAT3 "LPAAT-gamma, LPAAT3" ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865223-43987592 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 183.5;Early spermatids: 219.0;Late spermatids: 219.3;Rod photoreceptor cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.36e-2)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.50e-2)" "unprognostic (4.56e-3)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (4.88e-2)" "unprognostic (9.72e-3)" "unprognostic (2.14e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (2.84e-1)" "prognostic favorable (2.29e-4)" "unprognostic (1.50e-2)" "unprognostic (8.91e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" 20.9 20.9 41.5 19.2 47.1 11.1 15.1 42.3 34.9 11.7 14.8 22.0 44.7 10.3 12.6 25.7 12.3 13.8 27.8 38.4 36.0 53.4 53.2 18.8 16.4 52.1 41.8 10.4 21.3 24.6 14.7 12.2 39.2 13.8 11.9 61.9 30.5 11.6 62.3 24.3 52.4 8.7 47.8 19.1 18.0 26.4 48.1 15.4 21.4 50.2 10.3 15.4 15.0 48.2 73.0 40.0 10.0 27.5 17.8 20.4 7.7 32.6 40.6 40.8 25.1 40.3 51.4 24.5 24.3 39.3 38.4 27.8 17.3 36.5 11.8 117.2 45.8 10.8 24.4 54.8 33.6 39.6 23.5 25.1 30.4 36.1 15.0 35.1 31.2 8.0 61.4 39.1 15.0 31.2 0.4 22.9 4.7 28.2 28.5 40.6 11.3 65.9 29.7 70.2 34.0 24.7 40.0 45.0 29.9 3.9 31.3 42.9 46.6 25.9 0.3 39.1 34.0 31.0 50.3 15.3 33.3 78.3 23.9 0.0 3.3 2.2 1.1 7.4 1.2 0.9 1.6 1.7 3.8 1.1 1.3 1.5 0.9 0.6 9.6 0.9 3.0 1.8 41.5 47.1 42.3 34.9 38.4 36.0 52.1 41.8 39.2 47.8 48.1 48.2 17.0 12.8 25.4 33.0 7.0 8.0 9.3 14.5 7.4 40.3 19.8 12.3 33.4 25.8 21.0 25.8 183.5 15.9 10.8 45.1 9.8 25.7 219.0 17.7 16.6 16.3 13.8 12.8 34.3 29.5 1.1 10.4 19.9 18.5 5.1 24.6 15.4 68.7 19.0 65.6 37.9 19.7 12.2 32.6 27.3 219.3 7.8 25.7 1.8 17.8 38.5 34.1 9.2 19.1 28.7 26.8 18.8 5.7 11.8 18.6 60.5 52.6 31.0 184.0 6.6 14.9 24.4 7.0 2.4 17.4 11.1 12.0 14.4 22.0 22.5 15.7 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 51.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 25.5;HEL: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 4.8 2.1 14.7 1.8 30.5 5.2 4.5 24.6 22.5 7.2 5.6 6.4 1.2 7.8 2.2 3.7 6.1 4.2 2.6 14.9 22.7 6.0 0.8 6.7 0.9 47.1 26.3 7.4 2.1 0.3 11.4 8.7 34.3 3.6 2.1 2.2 2.7 2.4 1.0 2.3 2.6 4.7 25.5 4.6 2.3 2.8 28.6 1.3 4.1 1.0 1.0 3.0 5.0 51.3 0.5 1.0 25.5 5.1 4.7 9.5 1.1 0.9 0.3 1.9 3.2 1.5 4.6 0.7 1.8 4.2 11.8 0.5 4.8 4.0 1.8 2.9 8.1 19.4 4.9 0.1 3.7 0.2 2.8 11.4 1.9 5.0 2.7 9.1 6.1 3.1 9.8 8.9 2.4 0.0 1.4 2.2 6.2 0.0 9.7 0.0 1.1 0.5 5.6 0.4 14.8 5.6 4.0 2.1 1.1 9.9 1.1 1.2 6.8 2.6 3.3 1.8 4.4 0.7 1.0 0.0 9.9 1.0 1.6 0.0 1.8 0.0 3.4 1.5 1.1 0.2 1.6 2.1 1.0 0.5 0.8 1.2 0.3 2.9 1.3 0.8 1.7 1.3 14.7 30.5 24.6 22.5 14.9 22.7 47.1 26.3 34.3 25.5 28.6 51.3 12.0 3.2 5.5 7.5 4.5 3.2 5.5 9.7 6.2 2.4 3.5 2.7 5.6 5.7 6.9 5.5 0.0 20.3 31.1 6.1 0.0 5.2 52.1 23.8 12.5 13.5 1.8 31.5 87.9 8.2 12.0 17.8 4.6 5.1 11.4 20.6 10.4 0.2 18.2 0.0 95.8 0.7 10.2 7.2 16.4 72.8 5.9 17.0 3.6 23.4 9.4 4.0 9.2 56.3 407.6 5.5 18.7 8.6 15.7 1.3 0.0 0.6 21.4 1.2 19.7 5.3 6.9 4.9 2.8 1.1 2.6 22.2 14.1 3.7 1.4 3.6 AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708642-6761503 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favorable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" 5.4 11.8 6.7 2.9 6.8 2.3 4.9 7.2 8.3 6.5 6.1 8.0 3.1 6.6 7.9 8.5 7.4 1.8 3.4 6.6 7.4 7.2 10.0 4.5 4.1 7.8 7.4 5.8 6.4 3.3 10.3 4.1 7.6 6.0 4.2 5.2 5.0 5.6 11.3 3.5 6.7 2.9 7.6 4.8 6.9 22.5 7.1 4.7 4.0 2.7 3.7 4.7 5.8 8.7 8.5 7.0 15.3 6.8 3.4 5.2 9.4 4.3 4.6 7.9 7.0 4.6 7.3 21.8 3.2 3.3 10.8 11.0 9.5 9.5 11.2 4.6 6.6 27.4 7.0 10.5 9.1 12.4 10.0 7.6 10.0 6.7 9.8 8.2 13.6 9.5 19.9 10.7 11.4 6.3 23.5 20.1 20.4 13.6 5.8 15.0 15.0 8.2 7.9 13.1 24.4 14.8 4.1 7.9 9.4 8.1 3.6 20.5 5.5 10.8 5.4 4.4 12.4 4.0 12.8 11.3 7.3 13.8 12.9 1.8 1.9 1.2 0.7 2.4 1.6 4.4 1.3 1.4 1.2 5.1 0.9 1.1 0.2 2.7 2.2 4.4 1.2 1.4 6.7 6.8 7.2 8.3 6.6 7.4 7.8 7.4 7.6 7.6 7.1 8.7 15.7 3.2 4.4 58.8 46.5 9.1 18.8 14.2 19.4 7.8 14.2 10.5 5.8 11.5 9.0 7.3 2.1 9.4 23.5 17.4 3.9 11.2 40.0 30.0 27.9 22.3 22.1 50.0 45.0 10.0 14.2 10.4 27.0 83.6 18.9 10.6 10.4 41.9 12.2 6.7 46.8 10.1 14.2 16.0 4.6 34.7 15.8 12.6 7.2 33.7 7.5 42.3 6.2 56.8 60.2 10.2 16.0 15.4 22.3 30.4 9.8 22.5 14.6 9.8 6.6 14.0 24.7 26.2 10.9 30.9 10.4 18.5 17.4 15.0 25.2 11.9 AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 235.8" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 245.4;Proximal tubular cells: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" 42.0 29.8 43.7 10.4 44.6 31.6 30.0 43.3 46.1 17.6 48.2 23.0 46.6 14.4 33.0 34.1 34.4 24.5 54.1 44.1 49.1 102.0 235.8 19.9 10.7 45.0 43.4 34.7 31.0 31.0 36.6 11.9 46.4 22.7 18.8 33.9 19.8 24.1 23.7 16.8 45.9 15.2 47.1 20.1 20.8 15.7 51.0 6.8 42.9 32.5 14.8 29.4 26.1 52.5 32.6 25.2 20.6 56.9 29.7 22.3 7.6 28.3 57.1 26.8 61.9 37.5 81.5 20.0 40.5 66.1 41.7 42.0 26.5 79.2 64.2 67.2 63.0 5.6 35.6 157.3 40.8 46.0 2.7 32.9 76.7 35.7 129.6 88.2 10.9 30.8 4.0 67.6 59.3 45.6 14.2 9.8 40.8 37.4 27.6 20.2 61.6 36.6 100.6 77.6 75.5 42.4 35.5 33.2 17.2 36.0 31.7 96.0 3.0 25.2 27.8 22.7 33.4 99.6 95.1 2.1 59.7 9.5 26.9 12.0 6.2 9.6 6.6 29.3 15.1 9.6 12.4 10.6 33.0 5.6 13.1 10.0 11.3 11.8 35.4 2.9 9.7 9.2 43.7 44.6 43.3 46.1 44.1 49.1 45.0 43.4 46.4 47.1 51.0 52.5 40.8 16.0 27.7 114.9 22.0 25.0 51.8 82.5 27.9 68.3 69.9 65.4 73.7 72.9 66.9 51.5 25.0 79.6 8.6 12.6 52.8 60.3 22.4 99.8 25.9 32.8 39.5 29.3 204.3 31.5 10.5 42.2 26.0 83.1 36.8 90.9 36.8 229.6 32.7 53.8 245.4 33.3 59.0 40.1 42.3 7.0 32.0 37.2 55.2 100.2 18.2 74.3 8.2 105.1 172.9 25.8 65.2 38.4 47.7 35.3 232.9 261.5 69.1 36.9 32.9 41.7 50.8 5.6 17.3 53.1 45.7 108.1 18.5 61.5 42.4 53.2 AL136295.3 ENSG00000259371 "Novel protein" 14 24120956-24131829 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (1.38e-1)" "unprognostic (4.35e-3)" "unprognostic (4.81e-2)" "unprognostic (1.87e-2)" "unprognostic (6.61e-5)" "unprognostic (5.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-1)" "unprognostic (5.39e-2)" "unprognostic (1.53e-2)" "unprognostic (4.52e-4)" "unprognostic (2.37e-1)" "unprognostic (9.36e-2)" "unprognostic (2.23e-1)" 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.3 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL592490.1 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 11: Alveolar cells - Smell perception" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH16A1 MGC10204 ENSG00000161618 "Aldehyde dehydrogenase 16 family member A1" Q8IZ83 19 49453225-49471050 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059488 Approved NA NA 600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA059488: AB_2684037" "unprognostic (2.39e-1)" "unprognostic (3.95e-3)" "unprognostic (7.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-3)" "unprognostic (5.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.92e-2)" "unprognostic (4.90e-1)" "unprognostic (1.19e-3)" "unprognostic (4.28e-2)" "unprognostic (1.91e-3)" "unprognostic (2.94e-2)" "unprognostic (4.19e-1)" "unprognostic (1.27e-1)" "unprognostic (5.23e-3)" 18.5 14.1 3.0 9.7 3.4 10.0 14.5 3.5 3.8 17.7 3.6 13.9 13.9 15.9 0.8 15.5 12.9 3.5 8.5 2.9 3.3 14.1 17.1 11.7 10.4 4.5 3.8 11.3 18.6 3.8 7.5 5.0 3.6 10.3 2.3 1.0 10.8 4.9 7.0 16.2 19.1 3.2 3.9 28.3 14.1 5.2 4.2 4.9 12.4 1.8 4.9 12.9 13.8 4.0 24.6 32.7 7.8 18.4 3.5 2.3 26.3 15.5 4.9 11.8 12.1 17.1 9.3 36.8 24.9 2.1 2.8 16.7 3.1 8.9 1.5 23.3 19.0 28.7 13.1 24.6 5.1 17.6 61.3 4.3 5.0 5.7 4.6 2.4 7.7 12.5 20.7 37.3 3.1 24.8 12.8 51.9 17.1 10.6 0.0 21.8 11.1 28.1 5.7 28.7 14.1 16.1 13.9 15.4 13.4 1.9 14.0 20.3 17.4 17.4 11.3 8.0 17.4 31.4 38.2 10.7 4.3 24.9 12.6 11.2 10.9 18.6 9.3 26.0 9.8 17.1 9.1 10.1 16.4 17.1 8.4 8.8 1.8 8.6 29.8 17.4 7.9 8.1 3.0 3.4 3.5 3.8 2.9 3.3 4.5 3.8 3.6 3.9 4.2 4.0 22.3 6.4 11.5 1.0 27.2 9.9 28.6 19.2 21.1 9.2 10.8 8.6 4.0 12.8 15.5 11.0 8.4 33.7 19.5 27.6 5.9 22.0 1.5 6.3 6.3 16.9 13.1 20.0 1.3 24.5 28.7 16.3 21.4 8.0 17.2 12.9 15.4 17.4 46.2 1.7 1.2 16.6 20.3 29.9 14.7 2.9 28.0 20.2 16.0 3.7 31.4 6.4 15.5 1.5 4.2 14.0 26.0 8.2 17.6 9.1 43.8 22.9 24.3 7.0 19.7 7.2 15.8 3.6 13.1 19.7 10.5 40.4 13.8 27.6 23.7 28.3 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662160-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.2;Endometrial ciliated cells: 12.6;Glandular and luminal cells: 28.1;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 14.8;Syncytiotrophoblasts: 14.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 71.9;SK-BR-3: 70.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.3 0.0 0.1 0.1 0.0 0.2 73.0 0.0 0.0 14.4 0.0 0.1 0.1 0.8 6.8 152.2 4.6 0.3 0.1 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.3 5.2 0.1 3.2 0.0 3.3 0.1 0.5 17.3 4.8 0.3 123.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 2.4 0.0 0.0 21.1 8.3 41.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 7.9 0.0 0.0 0.1 0.0 1.3 3.5 3.3 0.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.9 6.8 0.0 0.1 9.0 0.0 0.0 0.0 1.9 0.0 13.0 0.0 0.1 0.0 70.7 0.1 0.4 15.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 1.7 1.2 4.9 1.2 0.0 26.2 7.2 0.4 0.0 7.3 5.5 0.0 10.6 0.2 0.0 1.9 1.1 0.0 12.6 2.6 0.2 0.0 0.0 0.1 0.2 10.6 0.2 0.0 28.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.0 0.0 0.8 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 53.3 14.8 14.6 0.2 0.0 0.0 7.6 ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" 2.3 2.6 1.3 2.7 1.5 4.1 2.8 1.7 1.1 1.9 0.9 2.3 1.6 2.2 2.7 2.1 3.4 1.8 1.0 0.8 1.5 1.9 2.9 1.8 3.7 1.9 1.2 2.3 1.5 2.3 0.6 2.3 1.6 2.6 1.9 3.3 1.5 1.9 0.9 1.9 1.8 2.1 1.6 2.9 2.0 2.6 1.3 3.6 2.8 1.3 2.9 1.3 0.9 2.2 5.3 5.8 4.0 7.0 4.6 4.3 14.0 5.1 4.7 5.4 9.8 8.8 12.6 10.3 7.3 2.6 8.2 7.8 7.9 6.8 7.9 13.0 7.2 9.2 6.7 3.9 1.8 11.4 8.1 4.0 3.6 11.3 9.3 2.6 3.7 8.1 13.9 13.6 5.5 6.8 8.4 6.3 15.1 3.2 7.7 6.5 14.8 8.3 3.2 7.8 3.8 3.0 9.4 3.8 5.6 11.7 8.6 3.2 7.5 7.4 10.7 11.3 6.5 7.4 14.7 17.3 5.0 4.8 6.2 0.0 1.0 1.7 0.6 0.4 0.9 0.8 0.9 0.4 0.6 0.8 1.1 1.3 0.1 0.8 0.5 0.7 1.2 0.5 1.3 1.5 1.7 1.1 0.8 1.5 1.9 1.2 1.6 1.6 1.3 2.2 3.0 6.4 0.5 1.3 5.1 1.5 3.0 4.3 2.8 4.6 2.0 1.7 0.8 2.8 5.1 5.5 4.2 6.8 3.5 1.4 1.9 2.4 1.0 3.1 2.8 2.3 1.2 7.0 1.5 3.8 5.5 2.7 3.1 2.2 1.3 3.6 0.7 2.9 3.3 1.7 1.8 1.7 2.0 2.8 1.9 0.3 1.5 2.2 0.0 1.9 3.3 3.4 1.0 2.5 1.8 3.3 0.6 1.2 4.0 0.8 1.2 1.3 3.9 4.2 0.0 2.5 2.0 12.4 5.8 4.3 2.7 3.1 3.2 2.6 1.9 1.8 ALG10B KCR1 ENSG00000175548 "ALG10 alpha-1,2-glucosyltransferase B" Q5I7T1 12 38316762-38329721 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (4.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.58e-2)" "unprognostic (7.40e-2)" "unprognostic (8.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.30e-3)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" 2.9 3.5 2.1 3.0 2.3 4.3 5.2 3.1 2.5 2.8 1.8 2.1 2.4 3.7 3.7 1.8 3.4 2.6 2.2 1.8 2.0 3.3 3.7 2.5 4.6 2.5 2.3 5.0 2.9 3.7 1.1 5.0 2.6 3.4 2.6 9.1 2.8 2.2 1.5 4.3 2.6 2.5 2.6 4.6 3.7 2.6 2.2 4.0 4.2 2.4 3.7 1.5 1.4 3.1 5.1 4.6 6.1 6.2 3.0 5.5 6.3 4.0 2.0 5.3 4.6 1.7 15.2 8.0 7.2 2.3 4.1 5.3 5.7 4.4 7.6 5.2 6.8 8.4 8.4 3.5 3.5 11.3 6.1 3.1 5.7 7.5 5.5 4.7 4.2 10.4 9.6 4.6 4.8 3.9 7.5 8.9 7.8 0.5 4.6 2.5 13.2 6.3 4.4 6.4 1.8 6.3 7.1 2.3 5.0 6.6 10.6 4.6 3.3 5.5 6.6 4.9 5.2 3.6 10.1 12.5 4.7 7.7 7.3 0.3 0.4 0.6 0.3 0.5 0.5 0.4 0.3 0.4 0.3 1.3 0.5 0.7 0.1 0.4 0.4 0.7 1.2 0.3 2.1 2.3 3.1 2.5 1.8 2.0 2.5 2.3 2.6 2.6 2.2 3.1 7.1 6.4 13.9 9.1 2.6 2.0 3.4 3.3 4.0 14.9 5.0 3.8 3.9 0.0 7.0 3.7 33.3 16.1 2.1 0.9 7.9 4.3 0.3 6.5 6.2 5.7 0.0 2.5 4.8 5.8 9.6 4.8 2.0 4.6 1.3 9.5 6.8 7.1 4.8 10.1 5.7 1.9 4.1 1.6 2.0 1.8 4.1 3.1 1.8 10.3 2.5 8.0 1.0 9.0 9.1 4.5 2.0 5.7 1.6 2.0 2.6 2.6 5.2 14.5 6.6 6.5 3.2 10.7 4.7 3.1 1.8 8.1 3.0 4.6 2.3 2.3 ALG11 "CDG1P, KIAA0266" ENSG00000253710 "ALG11 alpha-1,2-mannosyltransferase" Q2TAA5 13 52012391-52079232 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047214 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "HPA047214: AB_10961640" "unprognostic (9.21e-2)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (3.04e-2)" "unprognostic (9.15e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" "unprognostic (8.97e-3)" "unprognostic (8.89e-3)" "unprognostic (7.47e-2)" "unprognostic (2.30e-4)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.03e-2)" "unprognostic (9.71e-3)" 10.1 9.5 7.4 8.3 8.4 4.1 12.1 9.5 9.7 12.1 1.9 11.0 10.1 11.0 9.4 7.5 10.8 8.9 10.4 7.5 4.8 14.6 19.2 9.1 8.1 4.8 4.0 11.6 8.6 17.2 2.4 12.7 4.6 12.1 11.8 9.0 10.9 10.9 6.5 7.2 9.7 11.4 2.9 10.1 11.6 6.2 4.7 9.5 16.8 8.8 8.6 8.7 2.5 9.6 6.7 10.5 17.8 15.2 18.6 13.3 14.2 17.7 16.3 12.9 10.3 8.5 14.5 16.2 4.2 18.4 15.8 15.3 18.2 12.0 17.0 16.7 12.9 31.0 8.8 11.4 14.1 28.3 31.0 12.9 17.8 10.1 18.4 14.1 11.5 18.5 17.8 10.4 19.4 5.7 14.7 9.7 19.2 28.8 7.5 15.2 11.9 8.9 16.7 10.8 6.9 15.2 11.9 17.1 11.9 15.0 11.9 20.8 17.8 10.4 11.5 13.6 11.8 9.1 13.5 17.7 6.4 11.7 18.0 13.2 5.4 7.2 7.7 4.5 7.6 5.1 7.0 6.6 6.9 7.1 8.9 8.9 2.2 7.3 12.0 9.8 7.2 4.9 7.4 8.4 9.5 9.7 7.5 4.8 4.8 4.0 4.6 2.9 4.7 9.6 5.3 19.2 8.2 5.5 7.1 2.4 3.2 7.8 8.0 6.8 4.2 3.2 7.5 5.7 9.3 3.7 6.2 3.4 6.2 2.1 1.9 2.9 0.9 5.1 7.3 5.2 3.0 12.6 9.3 2.2 3.9 8.2 9.7 5.4 3.8 6.5 6.1 4.0 2.5 5.0 8.1 2.7 6.1 2.2 3.1 0.5 3.4 3.5 1.8 5.6 2.6 2.8 11.3 13.0 8.9 2.7 1.7 1.2 14.0 2.6 3.5 1.7 13.5 7.5 0.0 4.2 6.4 4.8 3.5 7.8 2.4 4.8 7.2 3.7 2.1 4.0 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 106.1;Glandular and luminal cells: 216.2;Hepatocytes: 115.6;Pancreatic endocrine cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 243.9;HDLM-2: 166.1;HHSteC: 120.3;RPTEC TERT1: 91.1;RT4: 146.8" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" 45.3 15.8 8.1 62.5 8.2 4.2 28.4 7.8 9.8 53.8 9.4 32.0 32.7 38.8 17.7 25.7 36.7 69.0 29.5 7.4 8.4 44.5 220.5 59.5 23.1 10.0 8.5 24.8 9.0 4.9 14.1 53.0 9.6 37.5 27.2 0.9 29.7 52.2 11.7 7.1 28.9 65.4 9.0 56.8 64.9 7.9 10.8 24.9 18.0 13.8 23.6 117.7 29.9 8.2 21.6 5.1 0.1 0.6 46.8 44.6 14.2 2.3 9.0 13.7 38.6 0.6 34.4 7.0 243.9 24.8 31.3 5.3 0.0 19.2 3.6 166.1 0.2 6.1 3.2 41.4 120.3 2.4 20.2 8.3 1.7 38.0 0.8 2.0 27.3 1.3 23.8 85.1 2.4 0.2 8.5 2.1 0.6 0.6 0.2 13.6 2.6 3.2 91.1 146.8 1.9 0.1 10.9 5.8 2.1 0.3 0.8 7.8 24.7 29.5 12.4 3.2 1.5 6.5 4.0 1.6 16.0 12.4 4.6 15.6 6.1 5.5 12.6 6.8 10.7 2.6 8.1 11.2 4.3 1.4 4.6 6.3 16.1 22.4 10.3 0.5 5.4 7.2 8.1 8.2 7.8 9.8 7.4 8.4 10.0 8.5 9.6 9.0 10.8 8.2 37.4 57.7 34.3 0.3 7.2 1.7 21.4 73.5 2.8 0.5 6.3 3.0 3.6 15.7 67.1 18.4 2.1 11.0 12.6 31.2 0.0 37.8 0.8 106.1 48.8 41.3 7.7 3.8 0.1 20.0 8.2 27.3 45.9 216.2 11.4 4.3 49.6 115.6 9.1 0.0 0.1 17.7 32.6 15.8 5.3 1.4 27.4 10.9 0.0 7.5 19.4 0.1 36.0 0.0 0.0 105.1 19.9 24.0 15.0 31.2 20.5 2.1 60.5 1.3 6.6 5.5 10.6 0.4 0.4 3.4 2.3 6.7 12.9 1.6 4.6 62.5 APOL2 APOL-II ENSG00000128335 "Apolipoprotein L2" Q9BQE5 22 36226209-36239954 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001078, CAB026695" Supported NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "CAB026695: , HPA001078: AB_10602432" "unprognostic (4.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.50e-2)" "unprognostic (4.26e-3)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.38e-2)" "unprognostic (7.39e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.22e-7)" "unprognostic (1.80e-1)" "unprognostic (6.79e-2)" "unprognostic (2.66e-2)" "prognostic favorable (5.06e-6)" 42.0 23.4 36.5 43.6 38.3 13.0 37.4 37.0 49.7 36.8 34.9 28.8 41.8 33.1 17.8 18.4 30.2 42.1 40.0 38.6 43.2 52.6 65.4 44.8 42.5 52.0 41.6 19.5 15.3 19.7 47.3 22.3 52.3 34.2 26.5 12.2 25.0 28.3 28.0 16.2 32.3 35.8 42.1 46.6 38.3 6.8 38.2 29.6 19.4 18.3 30.4 59.5 26.1 38.2 24.0 18.7 17.0 12.7 63.6 49.1 31.7 32.1 73.4 84.1 113.3 7.1 19.2 29.3 52.4 57.2 52.0 11.1 18.3 25.4 41.6 98.0 21.3 13.4 39.9 33.5 107.3 29.0 25.2 62.4 17.0 59.2 15.5 35.2 55.8 16.4 24.8 79.1 53.2 9.4 29.8 13.2 6.3 8.6 16.4 30.3 21.6 17.3 85.6 63.3 30.2 8.5 21.8 40.7 18.4 11.5 12.8 4.1 54.8 50.6 25.1 10.6 17.9 47.6 25.8 9.1 43.7 15.0 19.6 31.1 22.8 16.8 39.7 46.6 36.3 16.3 28.6 33.2 16.5 10.3 16.2 27.1 116.5 28.4 34.0 10.2 29.2 14.3 36.5 38.3 37.0 49.7 38.6 43.2 52.0 41.6 52.3 42.1 38.2 38.2 14.8 35.3 16.8 8.5 12.5 6.0 8.0 21.4 0.6 5.0 7.5 5.0 24.3 21.5 20.1 12.9 0.0 16.6 17.1 31.8 17.6 42.6 0.2 53.0 21.1 21.2 4.8 8.6 18.1 62.9 10.7 19.5 21.4 80.2 2.5 8.3 18.9 65.4 24.2 6.7 9.3 12.0 22.4 20.9 13.0 1.9 16.8 15.0 8.8 7.5 26.6 9.3 25.7 12.1 4.8 68.1 14.5 20.7 17.9 28.4 33.1 25.6 15.6 5.1 0.0 23.9 12.4 0.4 0.2 2.8 6.7 15.2 19.1 10.4 8.0 19.4 ARSF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;kidney: 7.6;skin 1: 5.6" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 1.9;Inhibitory neurons: 4.6;Oligodendrocyte precursor cells: 2.5;Proximal tubular cells: 10.5" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000549 Uncertain Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" 0.0 3.0 2.6 0.0 3.6 0.1 0.2 3.0 2.7 0.4 1.5 0.0 0.0 0.0 1.6 2.6 0.0 0.0 0.0 3.2 2.1 7.6 1.6 0.0 0.0 4.9 2.9 0.0 0.6 0.3 0.0 0.0 3.1 0.1 0.0 0.1 0.2 0.0 0.1 5.6 0.0 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.6 3.0 2.7 3.2 2.1 4.9 2.9 3.1 2.8 3.0 2.1 0.0 0.0 0.0 9.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 ARSH ENSG00000205667 "Arylsulfatase family member H" Q5FYA8 X 3006546-3034111 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (3.43e-1)" "unprognostic (1.95e-1)" "unprognostic (2.01e-2)" "unprognostic (8.90e-2)" "unprognostic (6.79e-2)" "unprognostic (2.56e-2)" "unprognostic (1.83e-1)" "unprognostic (8.56e-4)" "unprognostic (3.48e-2)" "unprognostic (2.39e-1)" "unprognostic (1.63e-1)" "unprognostic (2.65e-2)" "unprognostic (6.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934521-2968475 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.6;liver: 86.3;pancreas: 105.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 68.9;CACO-2: 42.7;GAMG: 30.8;Hep G2: 64.1;NTERA-2: 33.6" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" 0.4 0.7 2.6 2.2 2.7 0.3 1.1 2.1 2.8 1.7 4.5 20.8 17.9 3.2 2.2 0.4 4.1 8.2 1.0 2.8 2.6 36.6 86.3 2.7 0.1 2.8 2.8 7.1 105.2 0.0 0.7 0.7 2.9 0.5 16.7 0.3 1.3 2.9 0.2 0.2 13.6 1.9 2.4 0.0 2.9 0.4 2.6 0.0 0.2 0.3 0.1 0.5 1.6 2.3 4.5 68.9 8.2 0.0 3.3 4.0 1.3 3.9 6.4 4.0 4.0 42.7 0.0 0.0 13.7 0.1 30.8 0.0 0.0 0.9 2.3 0.0 4.5 0.0 0.0 64.1 1.8 0.0 0.1 9.6 0.0 3.8 0.0 7.3 3.8 0.0 0.0 0.1 10.5 0.1 0.0 0.0 33.6 2.4 0.2 2.8 1.1 0.3 7.1 0.0 0.1 0.2 0.0 0.0 2.6 13.7 0.0 0.2 5.0 0.1 0.2 0.0 7.4 0.0 0.0 0.1 9.1 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.7 2.1 2.8 2.8 2.6 2.8 2.8 2.9 2.4 2.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ASIC2 "ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG" ENSG00000108684 "Acid sensing ion channel subunit 2" Q16515 17 33013087-34174964 "Plasma proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.0;cervix: 3.4;endometrium 1: 3.4;retina: 4.6" "Group enriched" "Detected in some" 8 "Excitatory neurons: 1786.2;Inhibitory neurons: 666.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.0;RPTEC TERT1: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052112 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA052112: AB_2681733" "unprognostic (3.40e-1)" "unprognostic (2.45e-2)" "unprognostic (8.50e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-3)" "unprognostic (5.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" 0.0 0.6 13.0 0.0 11.4 0.0 0.1 4.4 10.3 3.4 0.0 0.1 0.4 3.4 0.0 0.0 0.6 0.0 0.0 12.4 6.0 1.1 0.0 0.0 0.0 6.2 6.0 0.0 0.0 0.0 0.5 0.0 3.3 0.1 0.1 4.6 0.0 0.5 0.0 0.1 0.3 1.4 5.8 0.0 0.0 0.3 6.2 0.0 0.0 0.0 0.0 0.0 0.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 11.4 4.4 10.3 12.4 6.0 6.2 6.0 3.3 5.8 6.2 8.2 0.0 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 25.7 0.0 0.0 1.3 0.0 0.0 9.2 2.1 0.0 0.0 0.1 0.0 0.1 16.3 0.1 0.8 0.1 6.0 0.0 1786.2 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 10.1 666.4 1.3 0.0 0.0 0.0 47.1 0.3 0.1 1.8 26.2 0.0 0.5 0.0 144.3 22.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.6 0.0 0.0 0.0 0.1 0.0 1.2 0.0 ASIC3 "ACCN3, DRASIC, TNaC1" ENSG00000213199 "Acid sensing ion channel subunit 3" Q9UHC3 7 151048292-151052756 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 12.5;Early spermatids: 15.6;Granulosa cells: 14.8;Late spermatids: 61.0;Spermatocytes: 10.3" "Group enriched" "Detected in many" 4 "glioma: 3.1;testis cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 16.7;U-266/84: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049155, HPA054805" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA049155: AB_2680657, HPA054805: AB_2732588" "unprognostic (8.71e-3)" "unprognostic (1.09e-1)" "unprognostic (1.92e-4)" "unprognostic (2.73e-1)" "unprognostic (7.06e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.42e-1)" "unprognostic (4.45e-2)" "unprognostic (8.64e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-12)" "unprognostic (1.49e-2)" "unprognostic (7.38e-2)" "unprognostic (1.65e-2)" "unprognostic (5.31e-3)" 2.8 2.1 8.2 0.3 9.0 0.6 2.7 11.7 10.9 13.3 6.7 7.9 1.1 7.7 1.5 1.9 7.2 0.7 10.9 7.9 8.8 4.8 4.0 3.2 0.8 9.3 7.9 6.4 2.1 0.5 18.1 0.6 10.3 5.3 0.6 8.7 1.6 0.4 6.0 2.9 4.1 0.8 7.0 2.8 3.8 19.9 8.6 0.6 4.1 0.9 0.7 3.1 4.3 11.5 1.5 4.0 1.7 2.7 3.7 0.0 7.4 0.4 0.2 0.3 0.5 0.8 1.9 0.9 0.4 0.2 1.8 2.4 1.0 0.0 0.7 8.9 4.5 1.7 3.4 0.0 0.0 0.1 3.9 0.9 0.7 0.2 0.0 2.9 0.1 1.1 4.2 6.8 0.5 6.3 0.3 0.4 1.8 0.1 3.3 3.1 1.7 0.5 0.3 1.4 2.3 8.2 0.6 0.5 4.3 4.9 1.8 0.4 0.1 1.4 2.1 4.3 1.1 16.7 10.2 0.1 2.3 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 9.0 11.7 10.9 7.9 8.8 9.3 7.9 10.3 7.0 8.6 11.5 0.4 0.0 0.5 2.9 0.5 0.6 0.0 0.2 0.0 9.7 0.6 0.6 2.1 0.0 0.2 0.0 12.5 0.2 0.3 0.6 0.0 0.2 15.6 0.9 1.1 0.3 0.0 0.0 3.4 0.4 0.2 0.3 0.5 0.8 8.9 14.8 0.0 0.9 0.6 6.7 4.2 0.1 0.0 0.6 0.9 61.0 1.5 0.4 0.0 0.0 0.6 1.6 0.0 1.5 5.1 0.4 0.0 1.9 0.1 0.3 0.2 0.2 0.6 4.9 0.0 0.7 0.4 10.3 5.6 0.0 0.9 0.7 0.3 0.2 0.2 0.2 ASIC4 "ACCN4, BNAC4" ENSG00000072182 "Acid sensing ion channel subunit family member 4" Q96FT7 2 219514170-219538772 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 10.7;pituitary gland: 22.0;retina: 6.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 223.4;Cone photoreceptor cells: 173.0" "Cancer enriched" "Detected in single" 38 "glioma: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 21.2;HMC-1: 6.2;K-562: 12.1;SH-SY5Y: 5.2" "Region enhanced" "Detected in many" "basal ganglia: 73.2" "Low region specificity" "Detected in many" HPA036042 Approved "Golgi apparatus" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "HPA036042: AB_10672998" "unprognostic (3.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.55e-1)" "unprognostic (1.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.74e-2)" "unprognostic (3.04e-2)" "unprognostic (2.54e-1)" "unprognostic (6.53e-2)" "unprognostic (1.90e-2)" "unprognostic (9.46e-3)" "unprognostic (1.88e-1)" "unprognostic (7.80e-8)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (5.51e-1)" "unprognostic (2.48e-2)" 0.1 1.1 6.1 0.0 4.2 0.0 0.0 4.1 8.4 0.4 2.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 3.9 4.9 0.0 0.0 0.1 0.0 5.5 8.4 0.0 0.0 0.0 22.0 0.0 4.4 0.1 0.0 6.4 0.0 0.1 0.0 0.1 0.0 0.0 5.7 0.0 0.0 1.3 10.7 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 4.2 4.1 8.4 3.9 4.9 5.5 8.4 4.4 5.7 10.7 3.9 0.1 0.0 0.0 0.3 0.0 0.1 1.6 0.1 0.0 223.4 0.9 1.0 1.1 0.0 0.0 0.0 173.0 2.5 0.0 0.7 0.0 0.0 6.1 0.0 0.9 0.4 0.0 0.0 0.3 0.4 1.0 0.9 0.0 0.3 17.8 0.4 0.0 0.0 0.1 0.0 11.6 0.6 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 10.0 0.0 39.2 0.4 0.0 2.5 0.4 0.1 1.1 1.3 0.2 0.0 12.8 0.0 3.1 0.6 0.3 0.6 0.0 0.3 2.9 0.4 0.5 0.9 0.3 ASIC5 "ACCN5, HINAC, INAC" ENSG00000256394 "Acid sensing ion channel subunit family member 5" Q9NY37 4 155829729-155866277 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "intestine: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014903, HPA029444" Approved NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: Spermatids - Spermatogenesis" "HPA014903: AB_1844498, HPA029444: AB_10611671" "unprognostic (8.52e-5)" "unprognostic (2.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASTN1 ASTN ENSG00000152092 "Astrotactin 1" O14525 1 176857302-177164973 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 14.9;brain: 29.8;retina: 14.0" "Group enriched" "Detected in some" 6 "Astrocytes: 191.3;Excitatory neurons: 218.7;Inhibitory neurons: 275.6;Oligodendrocyte precursor cells: 280.0" "Cancer enriched" "Detected in some" 14 "glioma: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.8;NTERA-2: 4.4;SCLC-21H: 2.7;U-2 OS: 3.4;U-266/84: 21.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074112 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA074112: AB_2686662" "unprognostic (4.41e-3)" "unprognostic (1.48e-2)" "unprognostic (4.03e-1)" "unprognostic (1.31e-1)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (2.03e-4)" "unprognostic (3.86e-3)" "unprognostic (1.08e-1)" "unprognostic (4.36e-1)" "unprognostic (1.67e-3)" "unprognostic (1.98e-1)" "unprognostic (6.77e-2)" "unprognostic (4.74e-3)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (1.16e-1)" 0.8 14.9 22.9 0.4 27.1 0.0 0.7 3.0 29.8 0.4 0.0 0.5 0.3 0.9 3.3 0.0 1.6 0.6 0.5 28.5 23.3 0.1 0.2 0.2 0.1 6.1 10.7 5.7 0.5 0.1 9.0 0.3 7.5 1.0 0.3 14.0 0.9 1.6 0.1 0.1 0.3 0.9 11.5 2.2 0.3 0.7 22.7 0.0 0.0 0.3 0.3 0.0 0.4 11.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 27.1 3.0 29.8 28.5 23.3 6.1 10.7 7.5 11.5 22.7 11.5 0.0 0.0 0.0 191.3 0.0 0.1 0.0 0.0 0.0 7.9 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.8 0.3 0.2 0.0 0.0 218.7 0.0 0.1 0.7 0.0 0.2 0.0 4.0 5.0 0.0 0.5 23.5 275.6 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 25.3 0.0 0.8 0.0 280.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.7 4.4 1.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 354.6;Excitatory neurons: 370.0;Inhibitory neurons: 1011.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 900.3;Oligodendrocytes: 225.9" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 37.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" 3.3 9.8 26.1 2.7 26.3 3.6 4.3 39.0 36.0 5.3 9.0 5.2 3.4 3.2 3.9 2.2 8.0 2.5 22.5 27.0 25.8 5.5 4.1 2.2 2.4 29.3 36.2 2.8 6.7 3.1 11.6 1.8 28.7 25.2 3.2 13.4 5.8 11.3 7.3 2.4 4.1 2.8 21.4 2.4 5.6 17.6 35.0 6.0 1.8 5.6 1.8 3.2 3.5 39.2 3.7 12.0 4.3 7.1 7.6 7.0 15.4 5.7 2.3 2.5 2.8 8.1 4.4 8.8 6.1 3.8 9.3 1.3 11.5 0.6 3.1 4.8 2.9 3.1 5.8 17.0 3.0 1.8 6.2 9.5 1.1 7.8 0.7 5.4 1.8 10.5 3.9 5.9 7.9 3.8 4.1 1.4 13.2 10.6 6.4 4.9 27.5 2.5 8.0 12.3 6.3 37.9 6.8 2.0 4.8 14.5 15.5 1.3 3.5 5.9 9.1 5.6 4.9 9.0 5.0 8.3 10.5 2.0 25.8 2.5 0.4 0.5 2.8 0.3 3.6 1.5 3.1 2.4 0.2 1.6 3.0 2.5 1.9 5.9 0.6 0.9 8.8 1.0 26.1 26.3 39.0 36.0 27.0 25.8 29.3 36.2 28.7 21.4 35.0 39.2 0.6 6.4 8.9 354.6 1.1 1.3 3.2 0.4 1.2 4.9 4.2 4.8 22.7 2.8 5.0 1.8 10.4 0.4 1.0 0.4 3.9 0.8 122.5 4.7 5.5 1.3 12.6 0.4 370.0 1.1 0.4 4.9 4.1 0.7 6.3 37.0 0.7 2.9 3.2 10.1 1011.0 1.0 0.0 0.0 1.6 228.2 2.8 1.0 0.0 36.5 0.2 3.0 0.0 900.3 225.9 0.5 2.1 5.7 3.6 11.7 5.7 6.9 11.7 5.1 0.0 1.9 2.0 7.7 13.2 0.3 0.6 0.3 3.8 1.9 1.8 2.2 ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.8;Late spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" 25.6 23.6 27.2 17.3 29.0 44.7 19.2 27.8 36.6 19.5 10.0 25.6 31.4 24.1 14.2 31.4 18.8 21.8 42.1 30.0 24.3 20.0 25.9 23.7 19.4 29.0 26.7 20.4 28.1 31.2 17.6 30.7 26.2 21.6 21.8 24.6 23.9 22.8 116.8 32.1 29.7 28.1 24.3 21.7 22.8 62.2 27.6 15.7 18.4 62.7 21.2 22.7 22.7 28.6 29.4 35.7 26.9 64.0 50.3 55.1 35.9 52.1 56.1 67.3 60.2 52.9 38.8 7.7 43.7 79.8 54.7 58.0 43.2 56.9 49.6 22.6 70.7 55.7 90.1 63.9 54.9 14.1 40.6 56.7 91.4 68.7 63.0 60.9 68.2 18.6 75.6 27.0 46.2 38.3 12.2 33.4 19.5 28.5 26.9 16.9 36.7 30.2 40.0 38.6 42.6 25.7 52.0 46.7 46.5 52.0 17.3 39.3 52.5 67.0 32.3 28.7 47.1 15.5 14.7 11.2 55.7 33.9 37.2 6.5 12.4 6.3 7.2 18.0 7.2 5.6 5.6 9.1 8.5 3.6 5.4 6.1 11.2 9.7 22.6 4.1 7.1 11.6 27.2 29.0 27.8 36.6 30.0 24.3 29.0 26.7 26.2 24.3 27.6 28.6 0.3 0.0 4.5 12.7 8.2 7.8 7.6 10.6 8.6 18.9 0.3 0.3 33.2 17.2 7.1 0.0 14.6 26.8 4.1 44.0 0.0 0.2 83.8 0.6 1.5 10.0 13.8 34.7 15.2 0.5 24.4 9.1 11.7 0.8 10.2 0.3 16.8 37.1 11.5 21.9 14.1 17.6 6.1 13.3 7.0 105.9 14.0 4.8 10.6 5.6 7.0 20.5 9.2 9.5 12.5 0.3 27.6 8.6 6.7 13.4 39.3 0.3 4.7 15.7 13.1 7.1 5.5 54.9 13.8 14.2 11.1 34.8 7.5 0.8 18.5 10.5 ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 138.6;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 136.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 22.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.9" "Cell line enhanced" "Detected in many" "HDLM-2: 19.8;SCLC-21H: 17.1;SH-SY5Y: 15.4;SiHa: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA027550: AB_10600983" "unprognostic (2.06e-2)" "unprognostic (7.57e-3)" "unprognostic (1.82e-1)" "unprognostic (7.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (1.23e-2)" 4.1 5.6 29.1 3.3 33.2 0.2 11.3 18.8 42.8 5.7 2.2 8.1 3.9 9.0 2.9 5.3 6.5 4.8 2.1 37.1 30.3 4.0 0.3 4.3 1.7 25.2 21.5 10.5 3.7 1.9 7.7 0.5 29.6 8.3 5.6 9.5 13.2 8.6 1.1 9.6 4.9 15.6 24.9 1.1 4.6 8.7 25.0 1.1 2.5 2.2 1.8 6.7 5.3 30.0 1.2 1.1 4.8 4.6 0.3 0.0 3.4 5.7 9.6 6.2 7.4 0.0 4.1 3.7 2.5 0.1 4.5 1.4 8.4 1.1 2.4 19.8 1.8 1.2 0.8 0.3 0.2 0.2 3.1 3.6 1.9 8.6 1.6 0.3 0.4 4.2 0.1 0.5 8.7 0.4 1.2 0.6 4.4 1.4 1.5 0.6 12.1 0.4 1.7 2.5 17.1 15.4 18.9 1.1 0.6 0.0 0.0 2.1 1.3 6.0 4.6 0.0 2.9 0.9 4.7 1.7 3.9 0.2 0.2 22.9 0.1 4.9 2.5 0.0 0.5 3.8 0.9 2.1 1.2 1.1 2.1 4.2 0.3 0.6 0.5 2.8 0.4 2.0 29.1 33.2 18.8 42.8 37.1 30.3 25.2 21.5 29.6 24.9 25.0 30.0 3.0 6.4 2.6 31.6 3.7 5.1 6.2 10.3 6.2 27.8 18.1 16.3 1.9 5.7 6.6 5.5 0.0 0.4 6.7 9.3 0.0 10.6 31.4 4.2 5.4 4.8 7.2 0.4 138.6 13.1 1.1 14.6 5.6 2.3 6.3 1.2 5.0 0.0 1.6 11.8 95.5 1.9 2.0 0.0 3.6 5.7 13.4 5.5 8.8 20.6 1.3 23.0 2.1 81.4 136.7 7.2 6.0 17.0 5.2 3.9 13.2 3.4 14.2 8.6 19.7 4.5 10.8 31.9 5.7 4.1 5.5 0.1 3.8 0.2 3.6 3.3 ATL2 ARL6IP2 ENSG00000119787 "Atlastin GTPase 2" Q8NHH9 2 38293954-38377285 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029108, HPA075302" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA029108: AB_10670557, HPA075302: AB_2732289" "unprognostic (5.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (9.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.09e-2)" "unprognostic (1.27e-3)" "unprognostic (8.22e-2)" "unprognostic (6.86e-2)" "unprognostic (4.28e-2)" "unprognostic (2.09e-1)" "unprognostic (6.33e-2)" "unprognostic (1.84e-1)" 19.1 32.4 15.0 16.9 20.4 32.5 41.6 26.6 18.0 29.1 16.8 52.5 33.7 33.4 19.5 41.9 29.5 18.5 16.7 17.1 14.2 28.1 40.2 22.9 19.2 13.5 13.6 37.0 15.7 15.8 13.5 16.8 12.0 31.4 26.7 25.4 51.8 31.2 53.7 50.0 31.4 36.0 11.2 20.3 31.7 17.9 16.3 27.9 54.9 46.2 35.1 27.4 33.2 14.7 84.3 36.0 51.0 37.2 44.8 27.9 61.1 31.5 25.0 33.9 38.7 40.8 65.2 61.6 33.7 20.2 47.4 94.8 64.7 32.2 56.4 74.5 44.7 38.9 26.6 58.7 24.5 47.1 35.8 20.3 68.6 32.7 45.2 21.7 34.6 23.5 60.3 37.5 28.7 31.1 56.0 46.1 64.1 89.5 22.4 46.9 50.4 45.4 25.9 43.6 26.1 44.2 32.0 40.3 38.2 39.0 22.1 28.7 21.9 34.8 52.4 33.2 57.8 48.8 48.3 79.0 23.4 47.9 42.7 1.3 2.7 10.6 2.3 2.1 3.8 2.8 2.7 2.7 3.4 4.3 4.1 3.3 3.3 2.5 3.8 2.0 3.6 2.4 15.0 20.4 26.6 18.0 17.1 14.2 13.5 13.6 12.0 11.2 16.3 14.7 18.5 12.8 32.4 62.7 18.7 36.8 32.5 25.9 14.8 20.6 40.8 33.8 7.6 11.5 44.8 7.3 14.6 15.7 14.9 12.0 7.9 11.7 22.1 12.3 17.4 17.0 6.6 22.9 66.3 5.0 14.7 16.5 11.7 17.8 4.5 14.3 14.3 34.4 10.8 21.9 55.5 11.7 77.3 8.5 16.1 19.5 14.3 12.9 12.4 59.0 8.2 8.6 7.2 46.3 20.4 5.7 8.7 16.6 13.1 23.9 17.8 12.6 23.5 21.1 32.9 16.9 19.4 16.7 21.3 46.4 46.9 14.6 13.6 9.0 12.7 31.3 ATL3 DKFZP564J0863 ENSG00000184743 "Atlastin GTPase 3" Q6DD88 11 63624087-63671921 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 264.4;Late spermatids: 728.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065702, HPA076616" Enhanced "Endoplasmic reticulum" NA NA 58000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065702: AB_2685536, HPA076616: AB_2732318" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.32e-2)" "unprognostic (1.62e-1)" "unprognostic (6.89e-2)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (6.09e-3)" "unprognostic (3.38e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (4.52e-2)" "unprognostic (1.11e-3)" "unprognostic (7.41e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-3)" 30.6 18.1 11.6 17.9 16.6 13.2 22.1 14.9 12.6 23.0 22.0 26.0 9.9 24.3 16.5 24.5 20.1 15.9 11.5 9.8 13.9 12.6 17.7 18.8 12.6 19.8 16.4 16.9 15.4 13.3 6.6 14.9 18.9 16.7 16.6 4.0 15.4 20.4 6.3 25.2 13.7 33.2 16.8 16.9 17.4 36.9 15.5 10.8 20.9 9.6 15.4 27.1 19.4 20.6 44.2 39.4 11.7 28.4 59.2 82.5 0.2 53.2 60.0 51.9 35.0 32.9 69.7 26.3 53.8 93.6 40.0 28.3 21.8 34.8 69.8 40.4 5.8 27.9 41.8 0.2 40.7 53.2 39.2 54.0 55.6 69.1 42.8 34.7 56.3 28.5 30.6 70.2 59.6 46.6 19.2 30.7 14.9 14.1 33.7 40.7 29.3 37.8 41.2 29.7 6.3 17.0 174.3 37.6 50.5 14.5 65.7 19.1 79.1 109.0 51.9 105.3 38.3 19.0 29.6 51.4 57.7 33.6 67.1 7.1 8.3 3.7 8.9 11.4 9.8 5.3 7.4 7.3 8.6 4.2 5.9 8.2 3.5 6.9 13.4 4.3 9.3 7.8 11.6 16.6 14.9 12.6 9.8 13.9 19.8 16.4 18.9 16.8 15.5 20.6 56.7 44.8 27.2 16.6 18.8 43.7 45.7 36.4 30.1 4.8 31.9 18.4 8.5 30.0 29.9 33.1 0.0 6.7 28.5 45.2 1.9 41.2 264.4 23.8 46.4 48.2 10.7 29.5 13.5 50.2 20.1 46.2 19.4 63.8 17.1 20.3 49.6 51.3 37.6 5.0 12.1 21.0 28.5 55.3 43.0 728.4 54.3 35.7 42.7 16.9 49.5 12.6 24.7 16.6 35.6 72.7 24.7 67.4 21.0 55.3 27.7 24.7 21.5 8.5 72.3 35.9 55.2 36.0 29.0 32.9 40.6 4.0 28.2 25.6 19.8 50.9 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 215.0;Cone photoreceptor cells: 235.6;Glandular and luminal cells: 176.3;Oligodendrocytes: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 10.2 10.4 12.3 8.9 22.0 18.2 6.1 18.3 16.8 13.0 5.7 4.4 9.9 10.1 5.8 7.0 8.7 15.0 21.4 9.7 12.5 12.7 10.1 39.5 5.8 25.3 22.2 6.5 12.4 23.1 16.2 10.1 22.9 4.3 3.2 14.9 9.0 3.9 13.1 8.9 8.3 9.1 15.7 8.9 5.3 8.9 21.9 8.2 13.9 17.3 6.1 6.5 5.9 40.2 28.0 14.0 17.5 20.5 8.7 11.7 30.9 13.0 7.6 10.9 8.8 44.5 31.5 14.1 15.5 11.0 14.0 23.2 15.8 10.8 10.5 14.2 14.9 16.3 11.9 23.3 13.6 30.8 25.5 7.9 8.2 13.2 8.0 8.8 29.0 12.6 11.4 2.3 7.7 10.5 14.1 19.4 7.5 31.8 9.9 12.2 7.1 8.1 59.3 6.4 27.8 7.7 12.7 16.3 10.7 22.4 6.2 40.4 19.2 0.0 23.3 14.1 9.9 7.4 15.5 5.9 4.8 28.3 12.2 0.0 1.1 1.7 0.4 1.6 0.3 0.6 0.2 0.2 0.6 1.8 0.3 0.2 3.1 0.0 1.5 0.5 0.0 0.3 12.3 22.0 18.3 16.8 9.7 12.5 25.3 22.2 22.9 15.7 21.9 40.2 25.6 218.0 215.0 22.2 11.3 10.8 3.4 4.9 1.2 42.0 5.2 3.7 42.3 31.5 29.4 16.5 235.6 1.7 7.0 2.4 5.9 32.7 0.9 51.2 24.2 34.2 12.0 3.8 35.0 11.4 32.2 16.5 8.6 176.3 12.0 62.2 27.1 16.5 20.7 13.5 32.5 3.5 14.2 33.6 16.9 1.9 11.1 29.3 10.6 48.7 36.9 11.0 6.2 33.7 138.3 24.3 6.1 4.9 7.7 7.7 10.5 15.7 13.3 44.8 0.0 9.5 12.8 4.0 10.1 6.3 9.7 8.6 8.4 8.7 5.9 3.9 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 20.6 10.7 4.7 24.9 6.9 70.6 17.4 15.9 7.6 19.1 13.8 26.3 24.3 18.7 14.6 45.4 13.7 21.1 14.1 6.0 6.3 18.0 18.3 16.5 27.9 7.5 6.1 20.5 21.0 29.4 10.3 14.5 7.3 28.3 29.0 30.8 19.4 13.4 11.4 28.2 24.0 19.5 5.6 21.8 51.1 31.6 6.6 44.6 16.8 16.8 28.4 25.7 22.5 15.8 69.7 9.7 20.5 28.7 42.6 46.1 19.3 32.8 41.6 23.2 27.1 23.7 34.0 31.3 53.5 44.0 48.2 40.4 24.6 31.3 40.2 73.9 20.9 76.7 13.1 5.2 24.8 62.3 47.3 31.5 34.7 26.1 37.4 34.1 37.0 48.7 27.7 94.3 37.8 22.9 50.3 19.1 14.5 38.1 19.2 21.2 59.8 37.8 28.1 55.8 12.5 22.0 86.2 10.7 36.9 18.3 11.9 43.7 36.6 35.0 38.7 30.5 56.2 131.0 125.5 58.1 24.1 25.3 20.9 5.5 1.0 4.3 1.7 1.0 1.7 2.1 1.4 1.7 1.1 1.3 1.2 1.8 3.8 1.8 1.0 2.4 1.2 0.8 4.7 6.9 15.9 7.6 6.0 6.3 7.5 6.1 7.3 5.6 6.6 15.8 26.8 16.0 13.2 34.6 27.8 34.3 25.7 15.9 26.2 12.2 13.8 9.7 15.6 18.6 16.5 20.2 14.6 12.8 43.0 44.6 0.0 12.5 34.1 19.0 22.9 15.7 6.7 26.1 81.6 16.5 3.8 19.5 46.4 22.1 11.4 14.0 16.1 16.4 10.4 38.7 64.3 30.5 16.2 19.4 26.4 23.8 19.3 29.3 14.2 45.9 19.9 8.4 27.8 67.8 132.6 25.2 27.0 21.1 55.5 35.8 24.3 7.8 19.8 31.4 19.7 24.1 17.7 18.7 11.4 43.8 44.6 9.6 40.9 7.0 27.3 45.4 ATP13A2 "CLN12, HSA9947, PARK9" ENSG00000159363 "ATPase cation transporting 13A2" Q9NQ11 1 16985958-17011928 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuronal ceroid lipofuscinosis, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037038, CAB037111, HPA050910, HPA054717" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB037038: AB_1840715, CAB037111: AB_1840714, HPA050910: AB_2681269, HPA054717: AB_2682583" "unprognostic (3.81e-2)" "unprognostic (1.84e-2)" "unprognostic (5.61e-2)" "unprognostic (2.17e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.33e-7)" "unprognostic (1.04e-1)" "unprognostic (9.71e-3)" "unprognostic (4.51e-1)" "unprognostic (9.85e-3)" "unprognostic (1.85e-1)" "unprognostic (5.75e-2)" "unprognostic (3.25e-2)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (6.84e-3)" 15.3 18.6 49.7 20.2 45.8 11.6 14.3 30.3 81.2 10.6 3.3 15.9 12.7 12.1 6.6 23.6 9.5 9.3 11.6 46.7 66.0 16.6 6.2 17.9 17.7 112.4 60.8 8.7 55.7 12.9 57.0 12.6 110.8 14.3 9.8 22.8 27.4 7.9 17.2 16.5 16.7 8.6 32.0 26.0 19.3 10.3 64.1 9.5 16.7 5.3 10.3 12.9 12.1 44.3 28.3 27.4 14.7 60.8 13.8 12.2 40.8 15.8 15.4 17.1 16.6 48.9 31.4 12.5 65.9 26.9 14.6 43.1 32.1 59.5 6.2 17.2 58.5 43.7 28.0 27.2 17.5 15.6 19.6 10.0 31.6 47.1 36.6 55.0 32.3 32.2 28.2 22.6 70.2 22.2 18.4 8.8 23.2 66.3 20.0 20.0 60.1 50.7 19.0 42.8 40.9 27.4 73.8 87.7 60.2 18.8 29.9 19.6 34.4 18.0 34.5 30.8 33.1 4.8 6.1 14.0 34.6 85.2 30.3 0.0 1.6 0.3 2.6 3.7 2.9 1.3 2.1 2.2 0.4 3.1 1.0 1.5 0.5 2.7 3.6 20.6 1.8 1.4 49.7 45.8 30.3 81.2 46.7 66.0 112.4 60.8 110.8 32.0 64.1 44.3 18.9 0.0 2.2 14.4 8.3 6.5 6.9 5.7 6.2 35.9 16.9 11.3 3.6 7.2 6.8 7.3 35.5 5.8 33.4 44.6 5.9 15.1 1.4 6.7 3.8 14.4 7.7 4.2 53.1 25.1 33.6 6.0 18.8 19.0 8.9 20.5 6.1 3.7 10.4 47.1 61.8 15.0 0.0 17.3 2.8 1.7 5.3 10.1 5.4 11.2 6.1 34.0 8.2 20.1 18.1 57.0 49.0 6.4 5.4 12.3 18.2 5.3 4.3 38.4 0.0 4.6 5.7 13.6 16.4 11.6 5.3 9.3 11.1 4.8 21.7 12.8 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1482.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1879.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 2979.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" 150.9 206.6 115.5 144.1 135.7 104.3 220.2 176.4 264.7 137.6 209.2 580.5 785.5 92.3 304.6 255.9 143.6 361.3 233.1 176.0 133.9 1127.5 132.5 255.7 89.7 140.8 103.5 137.7 661.3 1482.3 160.6 120.0 196.3 176.4 542.6 301.2 721.9 294.1 147.3 316.6 813.9 146.1 117.4 78.1 201.5 140.0 104.1 92.8 744.4 117.7 132.4 149.7 187.4 142.2 399.8 144.8 147.2 74.5 288.8 277.5 750.8 232.9 462.9 281.6 396.6 583.9 278.5 314.2 321.3 279.0 284.4 505.1 293.8 493.7 406.2 116.1 324.2 183.5 249.2 498.4 220.1 465.2 246.1 311.6 808.0 328.4 429.0 395.5 350.8 187.4 306.9 294.2 253.0 793.7 189.6 167.7 346.0 630.5 285.6 179.7 343.4 278.6 1023.2 405.1 143.8 126.7 363.0 679.6 2979.2 358.2 179.1 265.9 311.9 159.4 221.4 415.4 479.5 140.7 118.1 238.0 488.2 263.1 956.1 19.2 36.6 17.2 59.7 56.6 62.8 26.4 66.9 64.2 59.6 15.2 76.5 55.5 4.5 30.8 86.0 30.4 57.6 53.6 115.5 135.7 176.4 264.7 176.0 133.9 140.8 103.5 196.3 117.4 104.1 142.2 199.2 275.7 295.3 26.8 84.6 276.8 336.8 220.5 390.9 101.0 189.2 145.2 74.1 579.0 238.4 770.6 398.2 83.7 89.1 789.9 373.7 625.6 31.2 205.4 54.3 201.6 176.4 89.2 130.5 315.6 160.6 141.6 134.6 372.1 43.8 212.6 144.2 71.2 129.8 102.6 123.9 353.4 463.9 98.8 254.2 19.3 117.8 145.5 208.1 36.5 56.9 556.8 64.9 77.9 60.9 187.6 307.8 100.8 73.2 271.6 1879.9 308.2 171.6 147.7 32.9 109.8 147.4 20.2 35.8 320.7 268.9 67.6 133.3 58.3 498.6 280.6 ATP1A3 DYT12 ENSG00000105409 "ATPase Na+/K+ transporting subunit alpha 3" P13637 19 41966582-41997497 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Deafness, Disease variant, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 645.2;heart muscle: 157.7;retina: 292.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 418.1;Cone photoreceptor cells: 171.0;Horizontal cells: 213.7;Inhibitory neurons: 119.1;Late spermatids: 115.6;Rod photoreceptor cells: 291.4" "Cancer enriched" "Detected in many" 5 "glioma: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 57.7;JURKAT: 36.3;Karpas-707: 35.9;REH: 37.1;SCLC-21H: 128.2;SH-SY5Y: 57.7" "CAB033630, HPA045367, HPA056446" Enhanced Approved NA NA 220000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "CAB033630: AB_781528, HPA045367: AB_2679297, HPA056446: AB_2683136" "unprognostic (1.90e-1)" "unprognostic (8.65e-2)" "unprognostic (4.57e-2)" "unprognostic (8.20e-3)" "unprognostic (8.94e-2)" "unprognostic (2.52e-1)" "unprognostic (3.16e-2)" "unprognostic (7.66e-2)" "unprognostic (8.02e-2)" "prognostic unfavorable (3.44e-4)" "prognostic favorable (6.15e-5)" "unprognostic (4.02e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "unprognostic (3.45e-1)" "unprognostic (1.27e-1)" 0.2 18.0 115.4 1.4 126.3 0.6 0.1 76.0 645.2 0.0 0.0 3.6 0.9 0.0 0.0 0.3 0.0 0.2 157.7 165.8 275.3 0.1 0.1 0.2 0.9 390.1 61.8 0.1 0.8 1.2 15.4 0.0 320.4 0.2 0.8 292.4 0.8 0.0 0.2 0.3 1.5 0.8 26.3 0.5 1.3 31.5 174.9 2.1 0.2 1.8 0.6 0.1 0.7 200.7 0.0 2.1 0.7 23.1 0.0 0.1 0.1 0.3 0.0 1.6 1.6 0.8 4.3 57.7 2.6 0.4 5.6 0.5 16.2 0.2 0.6 10.7 3.1 5.0 0.2 0.4 0.0 0.0 18.2 0.0 0.2 0.0 0.3 0.3 0.0 36.3 0.0 35.9 0.4 0.8 10.4 0.1 3.0 8.4 14.3 37.1 18.5 1.8 0.0 0.6 128.2 57.7 0.3 4.2 0.1 0.0 3.4 2.6 0.0 3.0 3.2 0.0 1.1 3.7 2.6 12.7 5.5 20.6 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 115.4 126.3 76.0 645.2 165.8 275.3 390.1 61.8 320.4 26.3 174.9 200.7 0.2 0.0 4.4 9.1 1.1 0.3 0.4 0.0 0.6 418.1 0.3 0.3 19.3 0.0 0.0 0.0 171.0 0.0 3.2 0.8 0.0 0.0 43.7 0.1 0.1 1.4 0.0 0.0 59.1 0.0 0.1 1.0 1.1 0.1 1.3 0.1 0.0 0.0 0.2 213.7 119.1 0.4 0.0 0.0 0.4 115.6 1.8 0.7 0.0 8.4 0.4 40.0 6.2 14.6 11.4 0.0 0.0 0.4 1.0 0.2 0.0 0.1 0.0 291.4 0.0 0.7 0.4 21.2 2.8 0.2 0.3 0.3 3.6 0.4 0.5 0.4 ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904466 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 85 "skeletal muscle: 8241.7;tongue: 3199.6" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 65.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 30.0" "Region enriched" "Detected in some" 8 "thalamus: 13.1" "Group enriched" "Detected in some" 6 "basal ganglia: 1.3;cerebral cortex: 1.4;hippocampal formation: 1.2" "CAB002310, CAB032706" Enhanced Approved "Endoplasmic reticulum" NA NA 2800000 "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286" "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" 1.5 1.1 0.7 1.6 0.8 1.9 1.8 0.9 2.6 1.0 0.1 1.4 1.6 1.5 0.4 27.7 1.4 0.5 1.2 0.6 0.8 1.3 3.1 1.2 2.9 1.1 0.7 1.6 1.0 0.5 3.2 0.7 1.5 9.5 0.4 7.9 67.2 3.5 8241.7 2.4 2.2 0.4 0.7 1.5 1.1 10.7 1.1 1.5 2.2 3199.6 0.4 1.2 1.2 1.4 7.7 8.0 14.4 8.7 0.7 2.3 13.3 3.5 2.0 0.6 0.6 4.5 6.7 11.9 4.1 0.6 4.8 7.9 3.6 0.2 1.0 5.9 30.0 4.2 19.0 14.4 0.3 1.8 3.8 5.9 1.6 0.9 0.7 7.3 0.4 21.8 8.2 9.8 0.4 15.2 17.3 9.5 14.4 2.8 11.2 26.4 10.2 9.1 0.1 0.9 9.2 7.3 5.0 6.8 5.2 5.2 5.1 4.2 3.1 4.5 9.4 8.5 4.5 14.2 9.5 12.0 8.7 23.4 4.4 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.3 0.3 0.0 0.2 0.4 0.4 0.0 1.6 0.0 1.0 0.5 0.2 0.7 0.8 0.9 2.6 0.6 0.8 1.1 0.7 1.5 0.7 1.1 1.4 0.3 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.6 2.1 0.5 0.5 0.5 0.0 0.2 0.0 14.6 0.4 0.0 0.6 0.0 0.1 1.3 0.4 0.4 0.3 0.0 0.0 2.3 0.2 0.2 0.5 1.5 0.7 0.0 0.7 0.0 0.6 0.1 0.0 2.3 0.3 0.0 0.6 0.0 3.9 0.3 0.3 0.0 1.0 0.0 0.3 0.0 0.5 2.3 0.2 1.2 0.0 0.1 0.2 0.7 0.1 0.4 4.7 0.0 65.2 0.6 5.7 3.4 0.3 0.1 0.7 0.4 0.7 0.6 0.1 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 101.5;salivary gland: 185.3" "Cell type enhanced" "Detected in many" "B-cells: 82.5;Distal enterocytes: 120.7;Enteroendocrine cells: 97.8;Gastric mucus-secreting cells: 153.4;Intestinal goblet cells: 128.4;Plasma cells: 96.0;Undifferentiated cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 186.8;HMC-1: 266.1;JURKAT: 152.1;MOLT-4: 253.2;SK-BR-3: 195.2" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 6.8 13.7 6.8 62.2 8.7 98.3 7.7 20.0 6.1 6.0 15.3 55.0 30.7 9.1 1.6 9.7 6.1 13.7 8.0 3.0 4.5 11.4 4.6 22.4 101.5 2.3 12.8 3.1 64.0 2.1 2.5 2.8 3.9 20.3 33.0 0.2 185.3 19.6 3.3 28.2 75.3 6.3 2.0 98.2 92.8 2.1 11.6 97.5 11.7 3.3 58.7 17.0 7.2 2.3 0.3 7.6 0.3 6.8 0.0 0.0 0.3 0.4 0.9 0.2 0.6 2.5 1.7 186.8 11.0 0.6 0.1 0.8 3.1 0.0 0.0 23.5 2.1 98.0 6.0 0.1 1.7 108.0 266.1 0.2 0.0 0.7 0.0 0.1 0.3 152.1 20.1 117.1 0.1 116.8 253.2 115.5 1.2 53.1 1.6 27.5 0.2 43.3 0.0 3.3 11.5 3.4 1.5 195.2 0.2 1.1 12.2 26.3 0.5 0.0 2.1 0.4 0.1 43.4 14.2 66.0 2.5 75.6 0.1 16.0 1.4 33.7 10.8 0.9 8.3 9.8 6.7 10.3 1.6 11.4 4.8 6.0 13.1 3.8 0.5 15.8 6.4 6.7 6.8 8.7 20.0 6.1 3.0 4.5 2.3 12.8 3.9 2.0 11.6 2.3 7.1 0.0 1.9 0.7 82.5 0.9 0.4 0.7 1.2 0.0 4.7 1.7 3.8 2.8 2.7 23.9 0.0 0.2 59.2 120.7 0.0 1.3 0.1 0.3 0.4 7.8 97.8 22.5 0.5 12.1 0.3 1.9 153.4 0.3 33.0 0.2 8.9 1.0 2.8 0.0 0.6 128.4 36.7 3.1 2.5 0.2 0.0 17.8 12.4 5.6 5.0 0.2 28.8 0.0 0.3 25.2 50.3 0.7 96.0 4.2 14.0 0.4 2.7 0.2 0.0 1.0 3.4 0.0 1.5 0.4 0.3 0.0 38.4 0.4 65.6 4.6 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 781.6;Langerhans cells: 435.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 314.6;LHCN-M2: 501.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 18.5 11.2 33.0 25.6 92.0 106.8 19.6 14.0 59.1 18.8 0.0 33.1 40.8 18.2 12.1 14.7 18.6 25.2 11.0 52.7 4.9 16.4 22.7 21.3 29.2 0.0 14.4 13.1 17.1 21.5 11.0 27.3 0.0 13.9 32.3 71.2 11.5 14.9 24.4 26.0 30.1 19.7 0.0 30.7 29.0 23.0 10.9 18.4 14.4 24.1 28.8 37.0 10.6 34.9 24.0 117.8 45.5 22.1 64.5 102.2 20.9 71.2 232.6 67.5 106.8 47.7 21.6 46.8 4.9 99.3 77.6 21.0 40.3 19.7 187.5 16.2 46.9 16.6 39.8 41.9 209.6 70.7 26.6 85.0 36.9 210.8 314.6 78.9 17.5 17.6 27.9 16.6 501.1 37.6 22.1 30.1 35.6 32.9 55.6 31.1 146.4 19.7 64.4 108.5 42.9 23.4 82.6 22.9 20.2 91.7 33.9 7.8 12.5 181.8 29.4 67.6 78.9 12.7 21.2 49.1 82.6 19.6 41.0 9.4 39.4 22.3 20.9 42.5 26.4 84.5 36.3 26.8 51.3 84.4 13.2 16.8 127.1 27.0 86.1 9.0 53.7 21.8 33.0 92.0 14.0 59.1 52.7 4.9 0.0 14.4 0.0 0.0 10.9 34.9 46.0 44.8 46.0 90.8 226.4 201.6 71.0 29.3 76.2 370.9 30.9 109.7 20.3 45.8 30.0 53.3 154.3 176.8 139.8 181.5 1.9 27.6 2.3 29.3 61.0 63.6 91.6 31.5 781.6 28.5 42.1 91.6 44.9 59.4 31.6 45.5 49.6 39.5 193.5 302.9 279.1 30.7 16.2 116.0 435.1 9.6 29.2 285.4 55.2 126.5 157.1 96.4 50.4 193.5 91.9 25.5 80.6 32.0 133.9 54.7 75.0 22.1 20.6 113.3 32.9 97.0 69.5 44.5 130.7 30.4 204.7 228.8 125.1 76.0 65.9 90.2 ATP2C1 "ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1" ENSG00000017260 "ATPase secretory pathway Ca2+ transporting 1" P98194 3 130850595-131016712 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010207, HPA035116, HPA069684" Supported Supported "Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "CAB010207: AB_2061744, HPA035116: AB_10673106, HPA069684: AB_2686169" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.06e-6)" "unprognostic (7.66e-2)" "unprognostic (6.52e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "prognostic favorable (1.55e-4)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "unprognostic (3.06e-1)" 32.2 32.7 34.0 25.3 36.6 38.6 32.9 31.8 42.8 33.4 76.9 36.5 23.9 30.9 28.0 23.6 37.2 27.2 31.9 40.7 38.6 44.7 28.5 51.4 21.9 37.0 38.9 28.8 22.6 78.0 22.7 32.7 40.3 85.8 35.9 59.4 29.2 25.2 28.1 31.9 26.9 31.0 33.6 19.5 31.5 25.2 48.8 36.2 35.0 21.1 26.2 31.6 18.1 48.6 133.1 51.1 49.9 48.5 136.7 110.0 53.9 141.2 186.8 69.4 87.0 83.5 106.3 47.6 95.6 134.4 96.4 153.6 95.1 77.9 100.8 104.4 34.2 127.2 51.5 39.0 87.2 51.2 148.4 86.8 76.6 73.2 82.2 126.3 74.6 59.3 37.3 84.1 86.7 59.0 50.6 40.9 57.0 71.7 54.8 36.3 49.9 75.6 127.5 87.7 76.7 45.9 121.4 37.8 72.8 70.8 55.7 41.7 102.6 73.3 40.8 95.5 65.8 54.6 71.1 69.9 75.8 38.0 62.6 30.6 8.9 15.9 7.4 7.6 7.0 5.6 7.3 6.6 9.5 3.6 4.9 4.9 4.3 11.5 9.6 8.2 9.3 6.5 34.0 36.6 31.8 42.8 40.7 38.6 37.0 38.9 40.3 33.6 48.8 48.6 30.2 38.5 53.0 162.6 17.4 39.4 34.5 34.8 26.7 25.9 34.4 22.4 30.2 35.8 41.1 46.0 20.9 16.3 15.5 39.0 5.9 35.3 17.5 26.9 34.1 27.8 35.6 23.3 172.5 38.0 27.6 25.9 33.1 55.8 28.5 28.2 26.7 27.4 27.7 82.4 136.5 32.4 36.7 26.2 34.8 18.9 16.1 39.5 21.4 128.4 20.5 26.4 19.6 148.3 154.3 51.1 27.5 14.7 18.5 69.0 16.3 19.8 52.7 33.4 6.6 27.7 25.9 16.2 14.1 24.7 52.8 17.6 19.5 17.3 31.2 36.9 ATP5MC1 "ATP5G, ATP5G1" ENSG00000159199 "ATP synthase membrane subunit c locus 1" P05496 17 48892765-48895871 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1296.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 387.6;Distal tubular cells: 1449.8;Proximal tubular cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 2026.7" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "unprognostic (3.43e-2)" "prognostic favorable (3.88e-4)" "unprognostic (6.60e-2)" "unprognostic (2.09e-1)" "unprognostic (8.73e-2)" "unprognostic (4.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.53e-1)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (9.42e-3)" "unprognostic (9.78e-2)" "prognostic favorable (8.24e-6)" "unprognostic (2.07e-2)" "unprognostic (5.60e-2)" "unprognostic (1.95e-1)" "unprognostic (2.33e-1)" 99.1 160.4 210.3 97.5 218.8 116.5 134.1 230.6 265.5 101.7 218.0 359.5 215.2 113.2 179.8 197.7 121.4 58.8 764.0 221.0 230.8 284.4 258.2 81.4 103.5 219.4 211.3 88.4 117.3 268.3 125.6 82.4 217.5 101.2 344.4 117.1 127.1 118.4 874.7 130.9 187.1 149.9 213.2 99.0 195.4 47.2 220.7 129.5 133.2 1296.3 173.1 113.9 118.7 213.2 477.3 631.0 196.6 287.1 212.4 257.7 284.6 257.0 214.9 334.5 329.8 415.1 333.9 514.1 597.5 224.2 357.5 422.5 353.9 449.8 496.5 434.6 475.0 507.8 379.7 848.2 148.9 611.0 244.4 209.4 302.3 353.7 393.3 180.4 384.8 420.5 305.4 344.4 393.5 484.9 586.6 285.5 122.5 2026.7 617.4 364.0 511.3 832.9 645.8 266.7 290.8 210.7 192.0 409.1 227.3 296.6 602.2 411.3 214.2 210.3 288.3 322.3 333.1 309.0 382.7 706.8 302.5 476.7 255.7 75.4 328.5 91.8 193.7 299.5 236.9 463.9 220.0 209.5 448.5 375.2 293.6 253.9 18.2 270.6 179.2 555.2 211.7 341.6 210.3 218.8 230.6 265.5 221.0 230.8 219.4 211.3 217.5 213.2 220.7 213.2 139.6 48.1 87.9 0.0 43.2 0.0 0.0 0.0 0.0 0.0 214.6 312.5 0.0 0.0 49.5 274.0 0.0 387.6 48.6 0.0 1449.8 185.5 0.0 101.4 144.9 61.6 0.0 0.0 0.0 298.1 283.3 82.6 0.0 126.3 73.2 129.8 0.0 0.0 270.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 72.4 0.0 0.0 0.0 0.0 196.4 0.0 0.0 11.4 0.0 0.0 913.9 53.2 0.0 0.0 0.0 74.6 0.0 0.0 0.0 0.0 222.3 36.5 327.9 0.0 0.0 ATP5MC2 ATP5G2 ENSG00000135390 "ATP synthase membrane subunit c locus 2" Q06055 12 53632726-53677408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1335.2;Breast myoepithelial cells: 1873.6;Distal tubular cells: 1762.9;Hofbauer cells: 1076.1;Proximal tubular cells: 2061.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051469 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA051469: AB_2681496" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (3.01e-1)" "unprognostic (3.37e-3)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (2.97e-3)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (3.78e-2)" "unprognostic (5.71e-2)" "unprognostic (3.32e-3)" "unprognostic (3.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.42e-1)" "unprognostic (7.09e-2)" 250.6 297.8 487.0 240.0 510.5 445.5 485.5 498.2 574.6 338.4 492.0 444.0 383.6 279.1 463.7 340.5 533.7 296.1 759.6 475.9 499.0 437.4 469.4 243.6 406.4 509.5 488.1 487.2 499.1 503.0 18.9 265.3 507.8 322.2 551.7 275.9 483.0 284.9 1405.5 345.5 322.5 361.1 504.7 295.8 312.1 126.9 500.7 453.9 314.0 1447.2 540.2 365.6 15.2 519.7 325.4 684.8 701.3 640.3 478.0 1162.4 330.7 278.3 630.3 824.5 561.2 236.2 745.1 392.9 668.3 554.8 263.9 304.7 914.6 652.8 729.3 660.9 1096.7 1068.7 515.2 495.7 1034.1 819.7 508.5 1297.4 956.8 797.0 1315.9 1313.7 1078.7 468.0 776.8 1116.6 852.6 857.0 842.8 1996.5 603.6 681.5 756.7 838.3 665.2 981.9 1019.4 407.0 365.8 669.0 376.5 431.6 974.2 610.1 1403.7 1473.7 512.5 396.4 542.2 307.5 441.4 577.6 537.6 288.1 589.9 863.0 620.2 367.7 977.3 281.8 645.6 924.4 710.5 1119.6 826.1 693.6 1324.3 974.6 896.6 755.0 214.2 769.1 849.6 1023.6 955.8 1565.2 487.0 510.5 498.2 574.6 475.9 499.0 509.5 488.1 507.8 504.7 500.7 519.7 412.1 182.7 266.7 0.0 167.8 0.0 0.0 0.0 0.0 0.0 1335.2 1873.6 0.0 0.0 177.0 527.8 0.0 732.4 297.0 0.0 1762.9 470.7 0.0 529.1 446.9 190.2 0.0 0.0 0.0 676.5 777.5 222.2 0.0 454.1 224.5 715.4 0.0 0.0 1076.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.0 0.0 0.0 380.9 0.0 0.0 0.0 0.0 392.7 0.0 0.0 52.8 0.0 0.0 2061.3 215.7 0.0 0.0 0.0 248.9 0.0 0.0 0.0 0.0 507.7 182.6 802.8 0.0 0.0 ATP5MC3 ATP5G3 ENSG00000154518 "ATP synthase membrane subunit c locus 3" P48201 2 175176258-175181710 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1214.0;tongue: 1088.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 880.5;Distal tubular cells: 2666.7;Extravillous trophoblasts: 1022.6;Hofbauer cells: 1008.2;Proximal tubular cells: 2131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.45e-3)" "unprognostic (1.67e-1)" "prognostic favorable (9.90e-4)" "unprognostic (1.67e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.46e-2)" "unprognostic (6.03e-3)" "unprognostic (1.42e-2)" "unprognostic (7.90e-2)" "unprognostic (4.71e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.31e-6)" "unprognostic (2.86e-1)" "unprognostic (3.93e-1)" "unprognostic (4.55e-2)" "unprognostic (2.31e-2)" 195.7 199.2 134.9 131.1 142.0 141.2 164.5 160.3 155.0 126.4 168.1 343.9 378.7 127.8 126.5 305.3 107.3 75.8 1214.0 143.0 164.7 432.4 385.3 118.1 127.3 153.7 143.6 99.7 120.2 550.6 139.5 102.4 157.3 110.0 315.0 126.5 184.8 114.5 777.9 169.7 297.3 122.2 147.4 131.4 272.4 62.3 154.2 188.9 135.1 1088.5 176.3 171.8 165.4 150.0 268.4 232.3 346.7 381.8 290.0 255.9 387.1 242.7 255.1 334.8 290.9 700.0 216.4 661.1 276.5 272.0 365.7 343.3 440.2 419.9 348.5 278.3 411.7 538.7 312.1 896.6 225.9 702.4 308.8 279.9 317.7 377.5 239.3 257.4 341.9 313.2 587.0 305.1 370.3 361.9 541.1 587.3 460.6 638.4 726.1 417.1 321.5 648.4 664.5 590.9 310.5 196.3 195.1 521.4 557.0 487.5 313.4 567.0 231.6 55.9 263.2 1.7 338.0 239.5 327.1 582.4 319.8 420.8 251.8 115.2 293.9 126.9 168.4 332.1 170.7 202.4 176.5 184.2 425.2 163.2 164.2 181.1 32.6 197.9 309.4 314.5 204.0 438.5 134.9 142.0 160.3 155.0 143.0 164.7 153.7 143.6 157.3 147.4 154.2 150.0 250.4 176.3 157.2 0.0 69.0 0.0 0.0 0.0 0.0 0.0 324.8 399.4 0.0 0.0 125.7 310.8 0.0 880.5 134.2 0.0 2666.7 479.0 0.0 271.2 264.1 79.3 0.0 0.0 0.0 375.2 1022.6 154.1 0.0 301.5 88.3 236.8 0.0 0.0 1008.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 205.5 0.0 0.0 205.7 0.0 0.0 0.0 0.0 391.9 0.0 0.0 26.5 0.0 0.0 2131.8 129.7 0.0 0.0 0.0 181.9 0.0 0.0 0.0 0.0 690.9 81.0 469.5 0.0 0.0 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 1694.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2268.9" "Group enriched" "Detected in all" 4 "dendritic cells: 769.4;granulocytes: 2268.9;monocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA044281: " "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (5.69e-2)" "unprognostic (5.31e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (7.23e-2)" "prognostic favorable (3.24e-4)" "unprognostic (6.13e-2)" "prognostic favorable (3.62e-6)" "unprognostic (5.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (8.87e-4)" 78.9 162.2 222.2 68.3 225.4 286.4 79.4 234.5 267.0 63.8 253.8 94.8 61.1 57.5 97.3 101.0 61.5 64.5 107.2 231.3 256.2 233.8 168.3 115.8 71.6 235.4 232.9 49.7 172.0 182.0 157.5 76.6 251.1 101.4 90.8 106.6 112.1 60.7 138.6 98.9 83.8 55.7 232.2 143.7 124.9 56.7 244.0 60.1 101.7 84.0 74.7 92.6 70.9 255.4 150.4 135.9 99.4 129.1 149.3 78.0 142.9 134.1 168.5 217.1 183.6 143.2 144.5 140.3 119.7 119.0 253.2 118.4 233.4 170.1 99.8 135.4 266.4 175.0 209.7 195.1 238.0 262.7 307.9 97.4 219.6 235.3 206.5 136.7 105.1 167.3 189.5 260.9 177.1 147.3 103.2 411.3 182.4 184.8 271.1 150.7 108.1 371.7 225.2 159.1 260.9 137.2 89.0 303.1 319.0 111.4 128.8 419.5 62.8 119.0 105.7 222.6 311.4 241.9 397.5 150.3 161.2 355.5 188.5 528.7 1046.6 892.1 161.2 652.9 161.5 321.1 171.0 156.8 630.7 271.9 129.7 130.1 2268.9 124.4 618.8 769.4 187.2 1450.9 222.2 225.4 234.5 267.0 231.3 256.2 235.4 232.9 251.1 232.2 244.0 255.4 125.1 80.1 126.9 26.4 176.6 335.9 161.9 577.2 173.6 238.7 241.5 219.1 101.7 144.4 367.7 283.3 102.2 197.4 216.0 242.1 201.5 347.8 4.4 186.6 93.6 136.9 224.0 114.6 36.5 328.5 223.3 118.9 114.7 207.9 206.7 77.0 102.1 241.0 815.7 129.5 40.5 306.2 1694.7 347.6 454.5 12.9 78.9 489.8 281.1 24.4 379.2 220.2 103.0 28.6 62.4 379.0 382.7 65.5 301.2 355.1 186.0 223.5 244.1 231.7 78.9 77.4 444.3 116.6 197.9 192.9 358.3 496.5 121.2 135.9 241.8 337.5 ATP6V0E1 "ATP6H, ATP6V0E, M9.2" ENSG00000113732 "ATPase H+ transporting V0 subunit e1" O15342 5 172983771-173035445 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.24e-1)" "unprognostic (3.08e-1)" "unprognostic (3.61e-1)" "unprognostic (1.51e-1)" "unprognostic (5.34e-2)" "unprognostic (1.54e-3)" "unprognostic (2.25e-3)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (6.63e-2)" "unprognostic (1.47e-1)" "unprognostic (8.33e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" 265.1 267.9 135.7 158.7 142.2 89.7 223.2 145.3 192.0 220.8 181.0 204.6 127.0 199.1 634.0 228.9 193.3 163.3 262.4 133.0 154.4 338.2 237.0 253.3 191.4 156.2 145.1 189.3 179.4 145.9 314.2 171.7 154.5 232.3 154.6 45.8 245.0 154.1 225.0 178.9 189.5 157.9 150.3 270.1 233.3 93.4 144.5 130.1 241.2 137.6 188.3 227.2 199.1 158.3 249.4 263.6 85.5 259.5 777.8 310.6 200.6 475.7 444.6 235.3 361.6 299.2 376.6 107.0 663.0 567.4 622.2 174.6 173.4 342.2 260.6 741.8 170.9 100.8 242.1 287.3 379.5 192.9 340.6 413.0 413.3 270.7 149.1 284.0 287.0 116.9 67.3 306.3 519.3 487.6 121.7 278.0 99.2 195.8 228.5 128.8 121.9 193.0 471.5 312.4 123.9 82.8 208.6 255.7 400.5 235.1 282.5 265.5 430.2 553.0 125.9 397.8 405.3 263.2 587.5 120.2 299.5 318.6 185.2 2395.6 1150.2 1781.5 671.3 865.7 620.8 1088.5 761.2 706.6 734.6 951.6 734.7 761.7 2193.1 655.2 852.2 1099.7 853.8 2168.0 135.7 142.2 145.3 192.0 133.0 154.4 156.2 145.1 154.5 150.3 144.5 158.3 226.2 131.4 226.0 23.5 271.9 293.2 327.6 796.7 177.0 17.7 261.1 275.0 199.9 248.8 444.4 518.6 6.2 492.6 279.9 279.8 324.8 619.5 24.0 296.8 188.8 269.7 213.1 138.2 22.9 366.4 553.7 308.2 112.7 394.7 254.1 217.1 258.5 373.6 720.3 37.0 21.6 206.2 565.6 452.1 606.7 40.8 342.3 439.7 368.2 37.5 897.8 295.3 409.9 22.6 44.8 555.1 375.0 335.9 185.1 463.0 362.9 687.5 332.6 21.5 243.3 110.2 238.4 124.6 138.2 219.4 284.6 842.7 275.9 214.7 205.2 405.9 ATP6V0E2 "ATP6V0E2L, C7orf32" ENSG00000171130 "ATPase H+ transporting V0 subunit e2" Q8NHE4 7 149872968-149891204 "Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 328.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 123.7;Horizontal cells: 114.4;Muller glia cells: 173.0;Proximal tubular cells: 102.9" "Cancer enhanced" "Detected in all" "glioma: 89.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 148.8;SCLC-21H: 169.4" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (8.72e-2)" "unprognostic (4.73e-2)" "unprognostic (3.10e-3)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (2.42e-2)" "unprognostic (5.84e-3)" "unprognostic (3.57e-2)" "prognostic favorable (5.80e-4)" "unprognostic (1.21e-1)" "prognostic favorable (8.26e-7)" "unprognostic (1.96e-1)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.48e-3)" 21.8 30.0 270.4 11.4 284.5 5.7 17.7 242.5 309.4 9.5 149.4 33.6 7.6 9.3 9.2 10.5 21.9 9.4 117.7 328.6 256.5 57.0 118.0 12.9 23.3 305.6 287.9 10.4 22.7 41.5 134.9 4.1 324.6 44.3 8.0 50.4 66.1 30.7 16.4 14.8 19.0 9.9 236.5 24.0 33.8 8.1 300.3 30.9 55.5 15.6 13.5 12.1 8.8 235.7 26.2 72.2 29.6 96.3 11.9 1.9 18.5 13.4 18.2 36.0 36.8 25.7 32.1 53.5 55.2 17.9 37.5 22.9 63.2 22.6 15.4 69.4 70.2 16.7 21.0 148.8 17.8 12.3 35.3 4.1 23.1 39.8 2.4 27.9 30.2 66.3 18.3 25.5 2.6 45.0 8.8 28.2 25.7 33.7 50.6 57.8 1.2 24.7 28.4 28.0 169.4 96.0 17.4 60.0 41.9 7.2 33.9 8.1 5.7 10.4 11.0 109.6 50.3 35.4 49.2 26.5 65.9 21.4 34.4 4.4 9.0 2.2 45.9 17.5 41.7 19.6 56.5 53.4 18.5 17.8 71.9 66.6 1.5 38.6 22.2 8.5 92.9 31.6 270.4 284.5 242.5 309.4 328.6 256.5 305.6 287.9 324.6 236.5 300.3 235.7 3.7 16.0 11.3 35.6 14.1 4.2 4.1 3.4 0.6 123.7 31.1 23.5 29.6 21.5 8.5 27.6 25.0 19.5 23.2 1.9 54.8 45.5 0.4 13.6 1.9 6.7 22.2 9.5 39.9 12.8 4.8 8.8 10.2 20.9 10.8 21.9 11.4 65.1 24.7 114.4 62.3 26.2 22.4 10.2 4.1 1.6 5.3 9.9 44.4 14.0 6.4 173.0 27.8 34.7 34.2 5.6 0.7 11.3 4.5 15.0 0.9 102.9 6.7 78.9 6.6 8.7 10.0 0.9 13.2 6.9 4.4 5.1 38.1 6.6 2.5 5.6 ATP8B3 ATPIK ENSG00000130270 "ATPase phospholipid transporting 8B3" O60423 19 1782075-1812276 "Enzymes, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 5.9;testis: 21.9" "Cell type enhanced" "Detected in many" "Early spermatids: 9.5;Late spermatids: 11.7;Spermatocytes: 20.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.5;Karpas-707: 22.4;U-266/70: 18.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (6.50e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.05e-5)" "unprognostic (6.66e-2)" "unprognostic (7.91e-2)" "unprognostic (1.86e-2)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.55e-3)" "unprognostic (1.28e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (4.80e-9)" "unprognostic (8.05e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-2)" "unprognostic (1.19e-1)" 0.5 1.9 0.4 0.6 0.3 5.9 0.4 0.3 0.4 0.6 0.3 0.3 0.3 1.2 0.3 0.4 0.4 0.2 0.2 0.3 0.4 0.2 0.6 0.5 0.7 0.4 0.3 0.5 0.2 0.1 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.8 0.4 3.3 0.2 21.9 0.5 2.3 0.5 0.3 0.8 0.4 0.6 0.3 0.8 6.3 0.7 0.9 0.7 0.6 0.0 2.5 3.7 2.4 2.2 0.1 2.5 2.7 2.7 1.9 0.3 0.2 0.5 0.1 1.1 2.7 0.1 0.8 3.2 1.2 0.2 1.7 12.5 0.3 0.2 0.0 2.5 3.7 0.6 8.0 2.1 22.4 4.0 0.3 1.7 5.0 0.2 0.3 2.9 2.7 0.5 0.3 3.4 0.1 0.0 0.8 0.7 0.0 0.4 0.6 0.7 8.0 5.9 0.1 4.7 0.9 2.6 18.5 9.8 0.7 4.7 8.0 3.1 0.0 0.9 0.8 0.8 3.1 0.3 0.0 0.5 0.5 0.5 0.0 0.2 0.7 0.3 1.1 0.9 0.2 1.3 0.6 0.4 0.3 0.3 0.4 0.3 0.4 0.4 0.3 0.5 0.4 0.5 0.3 1.5 0.0 0.6 1.0 0.5 0.8 0.5 0.9 4.6 2.4 1.0 1.8 1.6 4.3 0.3 0.0 2.1 0.1 1.2 0.1 0.0 1.0 9.5 3.9 1.8 2.1 0.0 0.8 0.6 0.2 1.2 2.0 0.5 5.1 1.3 3.9 4.6 0.8 1.4 0.0 0.5 0.1 0.0 4.1 1.9 11.7 0.3 2.0 1.8 1.0 1.1 0.7 2.1 0.5 0.2 0.2 0.0 0.4 0.9 0.3 0.5 0.1 0.2 0.7 0.0 0.3 0.7 20.9 3.7 2.5 1.4 0.4 2.7 4.2 0.1 0.2 ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212027-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051353: AB_2681451" "unprognostic (4.58e-2)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.59e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.73e-2)" "unprognostic (5.35e-3)" "unprognostic (2.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-1)" 86.5 79.6 57.3 48.0 62.2 72.2 109.9 62.7 70.8 108.8 73.8 82.0 59.8 82.1 343.6 59.1 123.7 68.0 129.7 56.9 61.8 133.2 72.0 74.8 63.8 64.5 60.1 119.6 120.2 120.5 40.7 74.8 64.2 81.5 92.3 56.7 107.7 107.3 142.6 55.9 59.4 72.7 61.7 64.4 73.3 96.1 59.3 68.4 114.1 139.1 66.2 79.2 38.1 66.4 126.9 145.6 82.4 144.9 408.7 242.2 126.9 75.6 227.6 93.8 87.0 116.2 184.4 63.5 126.6 201.3 134.8 108.7 75.9 132.2 81.1 101.2 77.2 75.0 79.4 182.6 185.9 65.2 93.6 192.5 275.5 80.2 179.3 213.3 123.7 110.5 76.4 191.7 144.5 161.8 78.8 174.0 124.0 263.3 123.0 70.5 218.7 293.2 161.2 68.6 90.7 136.5 89.7 112.4 122.8 118.4 96.3 98.5 82.8 147.9 87.4 54.1 77.8 302.4 249.6 166.2 152.9 124.8 143.5 188.4 242.1 206.7 198.5 223.2 202.9 278.5 227.6 226.9 251.1 271.1 238.8 219.6 54.1 189.1 240.7 293.2 277.5 443.1 57.3 62.2 62.7 70.8 56.9 61.8 64.5 60.1 64.2 61.7 59.3 66.4 143.0 60.9 82.1 7.8 96.4 102.2 176.4 306.4 112.1 44.2 135.0 155.7 163.2 114.4 169.9 143.5 18.8 273.0 95.0 68.6 181.9 182.5 159.6 113.7 109.5 118.4 91.8 47.1 4.3 191.3 328.2 200.0 57.6 96.8 90.7 124.6 113.2 82.7 209.4 28.6 6.6 134.6 205.4 110.7 104.8 223.9 196.3 100.9 176.1 9.4 157.6 153.9 92.7 9.5 13.9 126.1 123.1 141.1 177.0 109.6 135.1 212.0 160.8 48.9 52.6 103.8 137.8 374.7 162.6 110.2 100.7 250.5 93.5 167.8 137.6 153.7 ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 101.6;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 89.5;Oligodendrocytes: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" NA NA 27000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" 12.8 19.1 10.5 10.3 12.2 8.6 17.2 9.3 13.2 16.5 8.9 11.8 55.8 11.8 15.6 10.4 11.7 13.9 19.1 13.4 12.2 23.9 62.8 14.4 7.5 8.0 8.7 14.0 20.2 40.1 8.7 22.6 9.0 12.8 12.3 24.2 13.9 13.2 11.6 14.9 33.4 14.9 11.3 13.8 24.0 16.6 10.8 7.8 32.3 14.2 9.6 15.7 9.1 15.8 40.8 37.6 21.9 18.4 37.9 61.5 28.1 26.6 37.5 27.4 23.1 16.3 27.1 0.0 17.5 37.4 33.8 55.6 15.0 58.1 36.4 4.5 12.8 12.7 10.0 35.1 22.8 27.2 8.3 33.1 46.0 29.0 27.8 34.3 36.0 8.7 20.2 19.2 27.0 11.7 11.1 10.4 14.7 13.2 22.3 9.2 50.9 30.8 24.8 28.5 12.9 20.2 26.7 48.9 36.3 21.3 26.2 25.5 44.7 29.0 17.0 30.8 26.6 13.4 20.1 0.1 17.9 17.9 29.6 3.6 3.2 2.0 2.3 2.8 1.0 1.4 1.2 1.4 2.8 1.7 2.0 1.7 0.0 1.5 3.1 2.6 1.8 1.0 10.5 12.2 9.3 13.2 13.4 12.2 8.0 8.7 9.0 11.3 10.8 15.8 11.1 16.0 10.4 70.2 5.8 6.4 4.3 14.1 6.8 22.5 9.9 8.8 12.6 20.0 10.3 11.0 37.5 7.4 8.0 6.5 1.9 8.2 7.1 9.9 15.1 11.1 9.6 7.4 101.6 14.6 8.4 12.7 20.4 11.8 7.0 39.3 17.9 50.9 10.4 37.0 101.1 10.7 4.1 14.2 6.7 5.4 12.5 11.5 7.2 64.6 10.1 11.8 5.2 89.5 85.7 10.0 14.3 7.9 11.4 7.0 34.6 7.3 10.2 20.1 32.9 14.3 10.9 21.3 21.1 8.5 7.2 5.1 5.8 21.0 12.6 5.2 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 AUP1 ENSG00000115307 "AUP1 lipid droplet regulating VLDL assembly factor" Q9Y679 2 74526645-74529760 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007674 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA007674: AB_1078251" "unprognostic (1.09e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-2)" "unprognostic (2.11e-2)" "unprognostic (5.97e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.00e-1)" "unprognostic (2.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (2.97e-9)" "unprognostic (9.68e-2)" "unprognostic (1.59e-1)" "unprognostic (3.35e-1)" "unprognostic (3.96e-2)" 48.0 42.2 68.0 44.4 69.0 78.8 52.6 71.0 85.8 56.0 72.1 76.9 70.6 38.7 78.6 49.9 45.3 46.0 38.4 67.6 71.0 48.8 106.9 48.7 41.3 73.0 69.6 38.1 127.3 77.6 2.1 60.6 69.7 38.9 81.0 32.4 89.1 46.3 57.7 42.3 68.5 55.8 70.5 39.5 56.7 24.5 70.1 42.5 50.9 66.6 51.5 69.6 20.7 72.1 114.2 133.4 55.3 87.5 183.1 107.7 124.9 89.1 152.6 122.3 77.3 196.9 130.6 126.4 61.9 126.5 210.3 143.4 140.4 115.1 98.5 100.1 128.7 153.6 71.2 180.7 181.5 97.8 127.9 128.5 256.7 174.4 198.6 101.1 117.3 105.1 202.2 164.5 134.0 124.6 79.0 200.6 111.4 298.3 111.9 95.3 150.0 270.3 139.3 90.9 80.7 79.6 65.2 200.4 162.2 70.8 90.2 156.7 59.3 162.9 97.2 50.6 146.8 87.9 88.1 120.4 129.6 155.9 184.9 113.8 132.9 108.9 81.9 169.3 89.6 90.6 81.0 82.0 124.6 113.9 72.9 75.8 68.8 85.3 144.7 118.3 107.9 132.2 68.0 69.0 71.0 85.8 67.6 71.0 73.0 69.6 69.7 70.5 70.1 72.1 64.8 67.3 44.6 22.5 97.3 73.2 120.7 161.1 80.8 31.7 71.4 59.6 34.9 74.4 108.1 68.0 14.6 140.0 86.6 150.4 23.5 125.2 24.3 36.2 50.1 74.9 73.8 72.4 17.7 208.7 217.3 73.0 121.8 58.7 89.9 57.3 50.0 114.3 161.8 37.0 16.1 127.7 136.3 83.5 95.5 29.7 44.4 95.2 97.8 17.8 67.2 74.5 72.1 14.6 23.4 153.1 141.3 38.0 229.9 141.1 196.0 59.6 46.6 43.2 59.2 60.0 104.2 85.9 64.6 95.7 78.7 223.8 77.6 68.4 134.2 143.9 AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 8.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062748 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA062748: AB_2684862" "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB005029: AB_562051" "unprognostic (3.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (5.67e-2)" "unprognostic (6.58e-3)" "prognostic unfavorable (4.52e-4)" "prognostic unfavorable (5.64e-4)" "unprognostic (2.36e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (6.07e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" 9.4 29.6 10.4 20.7 10.6 27.7 7.5 10.5 13.0 10.4 12.2 32.4 47.0 10.1 9.1 34.0 7.9 10.6 23.2 10.3 9.8 23.9 11.5 13.7 22.0 11.8 10.9 7.2 12.8 13.5 12.0 11.1 11.2 11.2 24.9 3.7 11.9 9.1 18.8 18.7 37.1 13.5 11.0 30.5 21.9 7.8 11.7 19.2 7.7 18.1 23.4 21.8 12.0 10.4 37.6 20.4 21.3 32.2 14.3 14.0 27.1 19.1 15.3 53.7 41.8 42.2 28.7 32.5 32.6 28.1 24.8 38.3 41.0 77.7 23.6 37.7 43.6 20.6 18.8 34.4 36.6 44.5 32.3 23.0 60.7 45.1 52.6 15.7 29.4 28.7 18.9 28.6 20.1 55.0 38.8 29.7 23.7 26.4 50.0 37.0 20.5 59.9 45.6 30.6 26.3 19.6 24.4 77.3 37.1 26.6 25.4 74.5 28.2 28.3 30.0 18.5 24.9 75.4 100.4 27.5 9.6 52.6 31.7 63.5 45.2 85.1 34.7 64.8 39.5 25.3 32.1 34.7 42.8 18.4 17.6 23.2 30.6 22.4 57.3 15.0 56.1 53.2 10.4 10.6 10.5 13.0 10.3 9.8 11.8 10.9 11.2 11.0 11.7 10.4 8.6 3.2 3.4 3.9 24.6 27.1 11.6 15.5 14.2 6.6 10.7 8.3 6.4 11.5 8.0 3.7 8.4 16.3 22.1 75.4 13.7 20.5 4.7 7.2 8.9 10.1 22.1 6.1 4.5 18.7 41.8 7.5 17.9 10.0 11.4 11.1 10.0 6.3 30.2 5.0 3.6 32.5 14.2 21.9 30.2 1.7 7.8 16.9 21.4 2.8 25.8 4.7 12.3 1.0 2.7 27.7 47.9 11.7 54.5 10.4 79.6 9.6 5.6 6.9 13.1 5.6 11.8 0.3 1.0 19.1 21.6 9.9 24.6 25.2 40.6 20.1 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" 48.5 36.6 102.4 26.0 95.3 13.9 35.6 83.7 112.4 30.2 61.8 86.9 28.5 43.0 30.5 46.8 35.4 24.7 37.3 89.8 88.8 35.0 20.9 34.6 13.9 94.8 94.0 31.8 53.3 52.9 38.1 23.8 91.7 47.4 31.8 51.9 52.2 45.5 24.2 46.5 34.3 41.5 101.0 20.5 54.2 25.1 108.3 10.7 38.5 19.9 16.4 55.6 34.9 92.4 24.1 23.0 25.6 19.0 43.4 39.2 19.3 43.9 28.5 21.8 24.9 16.3 42.6 16.8 14.2 26.6 27.4 43.9 15.9 28.1 29.4 8.9 12.7 18.4 44.4 30.3 26.6 20.7 30.0 30.3 54.0 17.6 27.1 30.6 18.6 2.9 17.3 18.0 27.8 17.8 1.6 14.5 8.0 33.4 41.3 12.8 28.1 8.2 19.7 45.5 31.7 18.0 20.8 31.3 31.2 15.6 20.6 15.5 37.1 35.1 24.8 27.6 23.1 22.0 12.7 2.2 21.6 16.0 43.5 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 102.4 95.3 83.7 112.4 89.8 88.8 94.8 94.0 91.7 101.0 108.3 92.4 9.2 9.6 13.1 0.0 2.6 8.7 9.5 12.7 5.7 20.0 11.0 8.0 28.9 4.3 13.6 5.5 25.0 5.3 3.5 16.8 13.7 8.0 20.1 11.1 10.4 10.8 18.6 2.1 0.0 18.3 4.0 10.4 9.7 12.1 5.7 12.0 11.4 7.2 5.5 20.2 0.0 16.8 6.1 8.4 4.0 6.1 11.1 5.5 7.2 0.0 7.5 7.4 2.1 0.0 0.0 25.5 11.0 21.4 4.5 17.2 16.3 9.2 12.2 12.7 6.6 12.6 15.5 0.5 0.9 10.8 11.1 5.6 1.5 8.9 10.5 17.6 BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.3;brain: 41.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 272.8" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.6" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 71.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" 9.1 3.7 16.3 8.3 30.5 26.3 5.3 24.9 23.2 5.3 10.2 3.8 1.7 4.1 10.0 2.8 5.9 5.1 5.7 16.5 20.2 3.7 2.6 10.3 2.3 27.9 27.3 4.6 2.5 0.3 3.4 2.4 26.7 4.0 1.0 6.7 2.2 2.0 1.6 2.7 3.9 1.8 19.2 11.0 3.3 5.4 28.6 0.4 2.7 1.4 0.4 5.3 4.7 41.7 0.8 0.8 0.4 0.7 17.7 3.8 1.4 1.0 1.8 0.4 1.3 0.5 0.5 0.1 1.7 1.1 2.0 1.1 0.0 0.0 0.3 0.3 0.2 0.0 6.7 0.9 4.9 0.2 0.5 5.6 1.6 1.9 4.1 1.8 0.0 0.8 0.8 7.6 1.9 0.6 0.1 0.6 0.0 0.8 2.1 0.0 0.1 0.3 0.0 2.0 1.0 0.9 1.6 0.1 71.6 0.8 0.7 2.3 0.2 0.9 0.5 0.7 0.3 10.3 0.8 0.7 4.8 0.6 1.2 2.6 3.9 3.9 0.2 4.6 0.2 0.7 0.2 0.1 2.6 0.2 0.1 0.1 37.6 0.1 5.1 0.4 0.3 1.9 16.3 30.5 24.9 23.2 16.5 20.2 27.9 27.3 26.7 19.2 28.6 41.7 2.7 25.6 59.3 9.1 11.4 36.3 6.3 54.8 18.8 2.0 22.0 7.4 3.3 14.3 57.2 1.8 0.0 14.5 5.6 22.5 0.0 3.8 8.3 5.3 9.0 16.4 10.3 29.0 0.3 3.3 23.4 32.4 9.2 9.0 76.4 1.9 21.0 13.8 37.1 0.0 0.7 10.7 22.4 75.4 272.8 2.9 15.2 49.0 55.2 1.0 14.1 6.0 3.1 17.1 43.0 3.1 21.0 6.8 5.9 11.8 28.0 5.6 37.7 9.6 6.6 16.1 20.8 3.2 4.1 6.2 32.7 20.4 24.5 0.9 11.9 13.2 BEST3 "MGC13168, MGC40411, VMD2L3" ENSG00000127325 "Bestrophin 3" Q8N1M1 12 69643360-69699476 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 69.1;tongue: 55.8" "Cell type enhanced" "Detected in some" "Early spermatids: 10.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 70.4;Skeletal myocytes: 28.1" "Cancer enriched" "Detected in single" 9 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "REH: 36.1;RPMI-8226: 38.4;U-698: 63.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054582 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA054582: AB_2682530" "unprognostic (1.53e-1)" "unprognostic (7.00e-2)" "unprognostic (9.83e-2)" "unprognostic (1.67e-2)" "unprognostic (5.15e-3)" "unprognostic (2.26e-3)" "unprognostic (7.30e-7)" "unprognostic (1.81e-1)" "unprognostic (1.74e-2)" "unprognostic (5.36e-2)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (4.82e-2)" "unprognostic (4.47e-2)" "unprognostic (3.03e-1)" 0.0 0.6 3.9 0.1 3.7 2.8 0.6 15.4 5.8 0.1 0.7 0.2 0.2 0.1 0.6 1.9 0.1 0.2 0.4 4.2 1.4 0.4 0.3 0.1 0.2 5.2 3.8 0.2 1.1 0.1 1.1 0.3 5.3 1.9 0.2 2.6 3.1 0.1 69.1 0.9 0.1 0.0 2.7 0.1 0.1 3.1 3.2 1.4 0.1 55.8 0.2 0.0 0.0 7.8 0.2 0.5 1.3 0.1 0.0 0.0 0.3 0.3 0.3 0.7 0.8 0.3 0.4 2.4 0.6 0.0 2.0 0.2 0.0 0.1 0.8 0.5 0.1 1.0 0.8 0.3 0.0 0.3 0.0 0.3 0.0 1.1 0.2 0.1 0.4 0.1 0.5 0.0 1.5 0.2 0.0 0.1 1.4 0.7 0.5 36.1 1.1 38.4 1.8 0.1 0.7 0.0 0.2 0.2 0.0 2.3 0.3 0.0 0.2 0.3 0.9 0.2 1.3 0.2 0.4 63.7 2.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.9 3.7 15.4 5.8 4.2 1.4 5.2 3.8 5.3 2.7 3.2 7.8 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 1.2 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 10.3 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 17.9 0.0 0.2 1.8 0.0 0.0 7.6 0.0 70.4 0.1 0.8 0.0 0.0 0.0 0.6 0.0 7.0 0.0 0.3 0.0 28.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 BFAR "BAR, RNF47" ENSG00000103429 "Bifunctional apoptosis regulator" Q9NZS9 16 14632931-14669236 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (4.88e-3)" "unprognostic (2.81e-2)" "unprognostic (3.15e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-2)" "unprognostic (2.11e-1)" "unprognostic (2.09e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (3.22e-1)" "unprognostic (1.07e-2)" "unprognostic (2.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.42e-2)" "unprognostic (2.51e-2)" 36.3 24.4 12.2 14.8 13.6 17.2 32.6 14.2 12.5 25.7 14.1 27.2 19.8 25.9 14.5 18.3 23.2 17.3 24.7 11.8 12.6 25.0 22.7 35.5 20.6 13.7 12.9 28.4 46.3 16.2 16.8 25.3 13.7 20.7 15.4 19.4 22.7 13.6 45.6 24.8 25.3 17.5 12.5 22.5 28.3 15.7 13.1 21.3 22.5 26.5 17.5 27.1 23.7 14.2 29.4 37.4 37.3 42.4 35.3 50.6 26.0 44.2 54.9 39.3 41.7 24.3 43.2 47.8 81.9 53.6 33.8 41.1 65.0 41.7 51.4 29.0 25.4 32.2 33.2 78.0 54.7 49.9 36.0 58.4 44.7 37.7 52.4 41.9 61.8 31.2 43.4 36.9 46.0 41.6 34.6 42.1 71.6 26.9 16.0 58.7 48.7 51.1 49.2 33.1 45.9 45.1 36.5 38.7 113.0 37.1 38.4 42.3 49.9 66.3 31.8 35.7 35.7 49.2 54.7 45.4 37.8 44.4 43.7 6.2 7.1 8.4 11.5 9.4 13.4 11.2 9.8 12.0 9.1 8.4 9.4 10.0 4.0 9.8 8.3 6.9 14.7 6.3 12.2 13.6 14.2 12.5 11.8 12.6 13.7 12.9 13.7 12.5 13.1 14.2 49.3 44.8 58.0 10.1 47.2 39.4 39.7 30.8 43.9 34.2 30.0 33.9 20.8 31.5 26.8 23.9 37.5 44.6 55.1 32.0 31.3 49.9 9.4 28.7 36.6 45.8 33.0 37.0 11.2 92.9 81.1 37.3 35.2 54.6 47.5 54.1 46.4 25.3 38.8 25.2 12.9 49.9 28.5 58.6 25.2 7.9 30.1 41.6 19.6 12.2 46.3 29.6 44.3 13.0 13.0 62.1 35.6 26.7 37.2 30.7 47.5 50.6 17.7 37.1 26.3 27.8 31.9 45.4 42.1 30.7 19.7 44.1 47.3 53.8 39.5 36.6 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BRI3 ENSG00000164713 "Brain protein I3" O95415 7 98252379-98310441 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 42.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042215 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA042215: AB_10794790" "unprognostic (1.51e-2)" "unprognostic (5.03e-2)" "unprognostic (7.08e-3)" "unprognostic (3.48e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.35e-4)" "unprognostic (2.04e-2)" "unprognostic (1.88e-2)" "unprognostic (3.93e-1)" "unprognostic (4.68e-1)" "unprognostic (1.66e-1)" "unprognostic (6.60e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.71e-1)" 132.7 159.3 42.2 37.0 45.0 94.8 102.2 42.8 46.2 88.3 50.0 94.0 67.6 80.1 31.7 63.6 72.1 45.3 150.6 36.4 42.0 122.6 179.4 167.3 32.9 46.4 44.2 73.9 127.4 24.1 98.5 69.1 44.3 84.6 35.8 10.8 93.5 26.4 237.0 82.1 81.2 33.6 41.6 122.4 133.1 53.2 56.6 14.1 78.8 65.1 18.3 99.3 69.4 46.0 130.5 20.6 36.6 47.3 231.8 104.0 86.6 105.1 122.4 86.6 114.5 17.1 60.0 13.6 220.3 191.8 275.6 45.5 46.9 66.7 59.9 46.5 53.4 8.7 15.0 29.9 228.2 10.0 43.3 85.7 95.3 74.2 135.2 119.8 107.6 15.9 26.6 84.2 164.4 9.1 32.1 32.9 44.1 87.8 55.3 30.8 20.2 43.7 83.2 9.3 30.6 62.3 27.7 114.4 279.2 63.2 12.2 64.0 108.4 175.1 103.4 228.1 82.6 91.5 128.3 35.9 199.5 44.4 91.8 2.5 15.0 24.2 0.9 25.3 1.3 0.9 0.9 1.0 7.0 1.1 1.5 1.3 42.8 0.2 24.0 10.3 3.0 3.1 42.2 45.0 42.8 46.2 36.4 42.0 46.4 44.2 44.3 41.6 56.6 46.0 354.9 83.3 120.3 18.3 52.8 146.3 278.2 24.1 47.3 90.6 191.1 277.6 121.9 204.5 37.4 134.3 33.3 122.9 118.4 193.5 569.4 62.1 680.8 176.9 149.2 223.9 78.5 49.0 13.8 119.5 431.4 161.6 122.3 192.0 22.8 140.8 238.1 258.0 695.0 129.5 17.8 161.9 26.4 482.9 329.4 132.1 100.3 503.0 167.2 20.6 167.5 291.4 28.8 15.1 26.6 82.4 234.2 121.5 37.4 416.5 261.5 670.8 35.8 84.2 111.7 166.2 145.6 61.6 58.5 59.0 171.5 169.4 48.7 131.3 154.6 473.3 BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62690275-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 292.1;pituitary gland: 237.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 35.9;Late spermatids: 53.1;Plasma cells: 86.3;Spermatocytes: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 242.1;RPMI-8226: 176.1;SCLC-21H: 181.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favorable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" 24.9 88.1 126.6 7.4 133.2 12.0 26.2 75.0 155.6 38.2 85.4 24.3 10.8 28.4 156.7 24.1 63.7 21.5 18.7 134.9 292.1 50.8 39.3 26.7 15.3 138.1 139.0 32.7 79.4 61.7 237.0 10.0 203.4 35.4 13.3 52.6 66.1 30.3 30.9 25.1 17.2 13.7 83.1 16.2 37.1 190.3 169.3 14.4 37.9 15.5 8.9 17.5 26.1 89.9 18.0 61.7 49.6 83.8 130.8 41.5 7.2 7.2 34.4 13.6 14.5 9.6 26.3 11.9 16.5 25.2 11.8 62.1 5.2 21.8 7.0 30.7 5.0 10.9 33.4 7.8 27.7 9.7 13.5 27.8 16.6 26.9 10.9 19.7 10.8 33.0 7.8 242.1 19.8 44.0 11.4 21.8 132.4 13.9 13.0 21.3 4.2 176.1 65.0 2.4 181.2 29.4 28.2 13.9 25.3 5.7 41.3 15.3 6.5 16.5 3.7 24.5 4.2 32.2 72.5 16.6 82.4 3.2 14.5 26.6 59.2 34.6 24.7 46.2 27.4 27.5 25.5 26.1 42.4 29.7 25.7 27.0 14.2 41.0 40.3 54.3 33.1 43.3 126.6 133.2 75.0 155.6 134.9 292.1 138.1 139.0 203.4 83.1 169.3 89.9 0.8 16.0 5.6 0.0 7.1 1.7 1.0 1.4 35.9 2.5 3.6 2.2 0.2 1.5 1.6 3.7 0.0 2.4 0.9 1.7 3.9 2.0 25.5 4.8 1.5 2.9 0.0 8.8 0.0 1.1 1.9 9.2 20.4 1.5 2.5 0.7 1.4 2.1 1.9 3.3 0.0 1.6 6.1 2.5 3.1 53.1 2.5 6.2 12.4 0.0 0.7 0.8 1.0 0.0 0.0 0.5 1.6 3.0 86.3 0.9 2.5 6.0 23.9 1.2 6.6 1.2 4.1 32.6 18.1 24.7 4.0 1.5 6.5 0.7 1.2 0.5 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C20orf141 dJ860F19.4 ENSG00000258713 "Chromosome 20 open reading frame 141" Q9NUB4 20 2814987-2815833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "testis: 130.2" "Group enriched" "Detected in some" 181 "Early spermatids: 1196.9;Late spermatids: 4648.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 21.6" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (4.52e-1)" "unprognostic (1.40e-2)" "unprognostic (1.35e-2)" "unprognostic (7.53e-2)" "unprognostic (1.21e-2)" 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 130.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1196.9 0.1 1.3 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4648.3 12.8 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.0 0.0 16.1 9.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.4;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 129.6;Pancreatic endocrine cells: 82.8;Prostatic glandular cells: 75.6;Syncytiotrophoblasts: 75.0;Urothelial cells: 132.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.4;U-698: 30.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" 1.2 1.0 0.1 1.2 0.2 0.6 2.7 0.2 0.3 0.7 0.2 7.5 3.3 0.9 0.0 2.6 0.7 5.0 4.0 0.2 0.1 4.8 0.3 3.8 1.2 0.0 0.1 0.2 17.4 0.0 2.0 3.3 0.1 1.7 13.7 0.1 3.8 3.4 0.5 26.3 5.2 0.9 0.1 0.7 13.7 0.9 0.3 6.6 7.6 0.1 2.0 5.8 1.6 0.1 11.0 2.0 4.2 0.0 0.6 0.0 1.8 15.5 6.7 10.1 11.3 26.4 10.1 0.4 1.9 3.1 4.4 8.7 6.1 0.3 19.4 0.0 2.8 7.9 1.8 1.9 4.6 0.0 0.1 0.6 8.7 5.2 15.0 5.4 2.2 0.0 2.8 2.8 7.5 1.7 0.3 0.0 12.3 7.9 0.6 0.3 13.2 0.0 18.1 16.5 0.5 0.9 2.4 5.2 6.3 6.8 9.5 0.0 5.8 3.6 5.5 0.0 0.0 3.9 0.0 30.1 2.7 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.8 16.0 10.0 0.3 1.6 32.5 129.6 10.0 45.5 0.0 14.8 3.3 2.1 4.3 19.3 18.4 0.0 18.1 0.7 30.4 0.0 26.3 24.2 24.8 3.1 3.5 11.9 0.0 3.2 35.9 25.6 4.7 64.2 44.1 0.0 0.4 0.4 0.0 1.9 0.0 0.6 56.6 8.2 0.3 2.7 23.3 0.3 1.0 1.8 1.0 2.6 0.0 0.0 0.5 0.3 82.8 30.7 0.4 4.6 75.6 7.8 2.1 14.8 0.0 0.0 4.6 4.7 3.2 5.3 44.0 33.5 75.0 2.0 3.0 8.9 132.5 C6orf136 Em:AB023049.8 ENSG00000204564 "Chromosome 6 open reading frame 136" Q5SQH8 6 30647039-30653210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 108.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046804 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "HPA046804: AB_2679815" "unprognostic (1.94e-2)" "unprognostic (1.71e-3)" "unprognostic (1.26e-1)" "unprognostic (8.01e-3)" "unprognostic (1.65e-2)" "unprognostic (2.76e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (4.72e-3)" "unprognostic (3.43e-1)" "prognostic favorable (9.16e-8)" "unprognostic (2.33e-2)" "unprognostic (4.54e-2)" "unprognostic (6.03e-2)" "prognostic favorable (7.51e-4)" 10.9 19.2 8.0 1.3 8.2 1.8 11.3 9.6 12.0 11.7 8.8 39.5 6.5 10.3 3.9 22.3 11.6 0.7 56.3 7.8 8.5 40.1 28.8 11.7 1.9 8.8 8.6 9.3 20.2 6.4 26.2 1.4 8.6 15.2 5.4 3.5 18.5 2.7 49.2 17.2 37.1 1.5 7.6 18.1 22.3 18.1 8.5 0.6 23.3 5.5 1.0 14.6 14.2 8.7 2.7 4.4 2.3 2.0 3.4 4.2 4.1 1.0 1.2 2.6 3.6 2.8 1.9 2.4 1.6 0.8 2.2 3.5 0.4 0.1 2.8 2.0 3.3 1.3 3.4 1.7 0.9 3.8 3.8 1.9 4.0 1.9 2.4 2.5 1.0 3.7 3.1 1.6 0.6 4.4 1.7 4.4 2.5 4.2 2.4 3.3 2.1 4.8 5.9 3.9 5.5 1.1 1.4 4.5 3.4 0.9 2.2 0.8 0.5 0.8 3.8 1.6 3.4 4.5 5.6 1.6 1.4 3.4 1.8 0.0 0.3 0.0 0.5 0.3 0.7 1.2 0.7 0.4 0.3 0.7 1.1 0.7 0.6 0.3 0.3 0.7 0.5 0.4 8.0 8.2 9.6 12.0 7.8 8.5 8.8 8.6 8.6 7.6 8.5 8.7 8.9 0.0 4.4 15.0 14.8 9.3 11.1 29.7 16.5 16.8 10.7 8.9 26.7 17.2 18.2 36.8 4.2 17.3 11.3 67.1 58.7 18.5 14.3 7.4 3.4 10.1 22.9 9.9 17.2 17.5 11.1 8.0 23.9 6.5 12.7 4.6 8.9 12.2 15.7 11.8 19.5 45.0 30.5 4.7 7.6 17.4 7.8 7.1 10.6 8.4 10.0 13.9 11.3 6.0 9.8 17.1 54.2 6.4 18.8 13.4 108.7 27.7 11.1 20.0 6.6 5.3 17.5 51.5 49.5 24.1 10.7 16.8 13.5 6.7 47.2 16.2 CACFD1 "C9orf7, D9S2135, flower" ENSG00000160325 "Calcium channel flower domain containing 1" Q9UGQ2 9 133459965-133470848 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.5;Gastric mucus-secreting cells: 67.2;Hepatocytes: 47.9;Paneth cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Group enriched" "Detected in many" 4 "B-cells: 2.0;granulocytes: 3.8" "Cell line enhanced" "Detected in many" "T-47d: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015280 Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015280: AB_1845833" "unprognostic (3.15e-2)" "unprognostic (4.25e-1)" "unprognostic (1.96e-3)" "unprognostic (4.48e-1)" "unprognostic (2.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-2)" "unprognostic (5.49e-2)" "unprognostic (3.97e-1)" "unprognostic (3.17e-1)" "unprognostic (1.67e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.83e-8)" "unprognostic (5.10e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (3.99e-3)" 5.1 11.3 6.4 1.9 6.2 2.4 7.0 8.2 6.9 9.5 6.9 19.9 5.8 9.9 5.3 9.9 9.3 4.5 11.2 5.8 6.0 28.2 58.6 12.8 1.5 7.5 6.1 10.7 18.9 7.9 19.0 1.2 6.0 13.3 2.8 2.1 15.8 4.0 9.0 5.4 14.9 2.4 5.9 7.3 28.4 23.9 6.5 0.9 17.4 1.8 1.7 11.8 6.9 7.8 0.4 2.1 4.3 2.7 0.8 0.1 2.5 2.0 2.9 1.5 0.3 5.7 4.8 0.2 4.2 2.0 2.6 1.2 2.2 1.6 0.0 1.1 1.4 0.6 4.8 2.5 2.5 0.0 0.6 0.0 3.2 1.3 1.0 4.8 1.8 1.1 0.8 1.8 2.4 3.7 0.3 0.7 3.4 3.3 1.5 1.4 0.6 9.3 2.9 1.7 4.9 9.1 2.5 5.6 0.9 2.6 9.5 1.6 0.4 3.5 2.2 0.6 0.1 3.4 4.8 2.4 1.1 0.3 1.1 3.8 0.5 1.6 0.2 0.0 0.0 2.0 0.1 0.4 0.4 0.7 0.1 0.5 0.0 0.6 0.2 0.2 0.2 0.1 6.4 6.2 8.2 6.9 5.8 6.0 7.5 6.1 6.0 5.9 6.5 7.8 1.7 19.2 19.6 3.3 5.5 2.8 5.5 5.0 3.4 4.6 13.0 8.9 9.8 21.5 8.8 20.2 12.5 1.9 1.0 75.5 3.9 22.0 13.4 9.8 5.4 3.8 29.2 0.0 5.8 33.1 3.3 4.0 67.2 15.1 4.5 5.9 5.3 47.9 3.6 3.3 4.8 43.1 10.2 5.6 2.2 8.1 8.1 2.1 5.4 1.9 5.9 6.7 2.1 4.5 4.7 26.2 53.2 7.5 3.9 7.0 31.7 16.5 5.2 9.8 0.0 3.4 4.4 13.7 14.7 2.9 1.6 2.9 1.9 2.9 24.5 6.2 CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 99.3" "Group enriched" "Detected in many" 8 "Bipolar cells: 101.4;Enteroendocrine cells: 214.1;Excitatory neurons: 318.3;Horizontal cells: 249.0;Inhibitory neurons: 372.1;Oligodendrocyte precursor cells: 271.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in all" 4 "cerebellum: 99.3;cerebral cortex: 30.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 45.1;U-87 MG: 23.9" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" 1.0 2.3 15.4 0.3 15.8 0.1 0.9 99.3 30.4 0.6 0.0 0.7 1.2 0.8 1.1 0.2 3.2 0.1 0.6 15.1 6.8 0.5 0.2 0.2 0.4 7.2 11.2 0.9 2.6 0.1 4.2 0.0 10.6 0.4 0.4 7.1 0.2 0.1 0.5 0.3 1.7 0.2 9.4 0.6 2.7 2.3 11.3 0.1 0.7 0.1 0.2 0.3 0.7 15.2 0.0 0.1 0.1 6.0 0.2 0.2 0.0 2.2 2.5 0.3 0.0 0.0 0.0 0.2 0.0 0.2 5.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 2.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.1 0.2 1.4 0.1 0.3 0.6 0.0 0.1 0.0 0.1 45.1 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.1 0.1 0.9 0.2 0.1 0.0 0.0 0.0 23.9 0.1 0.6 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.0 15.4 15.8 99.3 30.4 15.1 6.8 7.2 11.2 10.6 9.4 11.3 15.2 7.7 6.4 3.2 31.3 9.6 0.6 3.4 0.0 0.0 101.4 3.1 7.4 2.8 0.0 1.3 1.8 16.7 0.0 2.9 0.6 0.0 0.5 27.1 1.2 6.3 6.5 214.1 0.4 318.3 0.4 0.2 4.7 10.7 2.6 1.3 5.2 1.8 1.2 0.5 249.0 372.1 5.0 4.1 1.9 1.4 28.0 1.2 2.1 0.0 28.1 1.2 3.0 4.1 271.9 11.5 1.5 0.1 0.4 0.5 0.8 0.2 2.0 3.7 7.0 0.0 5.1 17.6 4.3 7.1 0.4 0.1 0.3 2.0 2.5 1.0 0.9 CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970786-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 20.7;heart muscle: 27.1;intestine: 29.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 606.7;Horizontal cells: 301.2;Inhibitory neurons: 476.2;Oligodendrocyte precursor cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "HDLM-2: 87.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" 3.0 0.9 4.5 1.4 0.9 0.0 1.9 0.0 3.0 5.6 0.0 29.9 0.7 20.7 0.5 2.1 4.2 2.3 27.1 2.0 0.5 2.5 0.4 4.6 0.3 0.0 0.5 1.9 0.9 0.1 5.2 2.1 0.0 6.5 1.3 1.7 1.0 3.3 0.9 1.3 5.0 10.2 0.0 3.0 5.4 2.5 1.8 0.2 1.3 0.8 0.3 12.3 3.4 0.1 0.0 0.0 0.1 0.0 3.3 2.0 0.2 3.4 4.1 2.2 1.5 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.8 87.0 0.8 0.1 0.0 0.0 2.1 0.0 0.1 5.1 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.4 0.6 5.2 0.0 0.1 0.2 0.0 4.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.5 0.9 0.0 3.0 2.0 0.5 0.0 0.5 0.0 0.0 1.8 0.1 2.2 0.0 0.0 96.6 0.2 0.6 1.0 0.0 0.0 20.7 0.8 8.3 48.8 0.0 0.0 0.0 2.1 0.2 1.3 0.6 0.0 0.1 35.6 5.1 14.6 5.2 36.6 0.8 606.7 0.0 0.4 4.2 2.0 0.9 0.0 2.7 2.2 0.1 0.3 301.2 476.2 0.6 0.0 0.0 1.1 90.3 0.9 0.2 0.0 72.1 0.0 6.0 1.0 194.5 21.7 0.4 1.2 4.1 0.2 1.2 0.0 0.1 0.0 1.3 13.1 1.6 26.7 3.4 5.8 0.1 0.1 0.1 1.1 0.2 0.5 3.1 CACNA2D3 HSA272268 ENSG00000157445 "Calcium voltage-gated channel auxiliary subunit alpha2delta 3" Q8IZS8 3 54122547-55074557 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.8;skeletal muscle: 9.9;tongue: 10.7" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 828.3;Inhibitory neurons: 456.4;Oligodendrocyte precursor cells: 317.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.1;HAP1: 1.9;HeLa: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030849 Uncertain Nucleoplasm NA NA 69000 "Cluster 47: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA030849: " "unprognostic (6.92e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-5)" "unprognostic (5.53e-3)" "unprognostic (2.64e-3)" "unprognostic (3.24e-1)" "unprognostic (1.17e-2)" "unprognostic (5.84e-3)" "unprognostic (7.22e-3)" "unprognostic (1.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.00e-1)" "unprognostic (1.47e-3)" "unprognostic (2.19e-1)" "unprognostic (3.62e-2)" "unprognostic (6.95e-2)" 0.2 4.1 8.8 0.1 11.6 0.0 0.2 0.0 15.8 0.3 0.0 0.7 0.1 0.1 1.3 0.5 0.4 0.2 2.6 9.4 8.4 1.3 0.0 0.5 0.5 2.1 10.2 2.5 0.0 0.3 0.8 0.5 1.3 1.0 0.3 2.9 0.4 1.5 9.9 0.1 0.3 0.6 0.0 0.2 0.4 1.4 3.5 0.1 0.4 10.7 0.5 0.1 0.4 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 9.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 11.6 0.0 15.8 9.4 8.4 2.1 10.2 1.3 0.0 3.5 9.9 0.5 0.0 0.0 160.9 0.6 0.3 0.4 0.2 7.4 10.8 0.2 0.5 30.2 0.0 0.7 0.0 8.4 9.9 5.5 0.1 7.9 0.0 83.4 0.9 0.8 0.6 0.0 1.3 828.3 0.6 3.2 3.4 1.5 1.8 0.0 1.1 0.4 0.0 5.9 0.0 456.4 0.0 2.0 8.9 2.7 56.1 2.8 11.0 0.0 97.4 22.2 5.0 0.0 317.7 11.3 1.2 0.0 1.5 0.1 0.4 0.0 0.2 0.8 1.4 6.6 1.7 1.9 5.7 2.9 3.4 0.1 68.0 0.7 0.8 0.0 0.4 CACNG5 ENSG00000075429 "Calcium voltage-gated channel auxiliary subunit gamma 5" Q9UF02 17 66835117-66894751 "FDA approved drug targets, Predicted membrane proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 11.2;retina: 15.8" "Cell type enriched" "Detected in some" 14 "Oligodendrocyte precursor cells: 74.9" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "olfactory bulb: 124.3" "Low region specificity" "Detected in many" HPA050115 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 68: Oligodendrocytes - Mixed function" "HPA050115: AB_2681022" "unprognostic (1.85e-3)" "unprognostic (3.84e-2)" "unprognostic (1.44e-1)" "unprognostic (2.46e-6)" "unprognostic (4.52e-2)" "unprognostic (1.29e-1)" 0.0 0.0 4.8 0.0 3.3 0.1 0.0 1.3 5.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.5 0.1 0.0 0.0 0.4 3.6 6.4 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 15.8 0.0 0.0 0.1 0.1 0.0 0.0 6.2 0.2 0.0 0.1 11.2 0.1 0.0 0.0 0.3 0.0 0.0 3.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 3.3 1.3 5.9 2.1 3.5 3.6 6.4 2.3 6.2 11.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CACNG6 ENSG00000130433 "Calcium voltage-gated channel auxiliary subunit gamma 6" Q9BXT2 19 53991637-54012666 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 90.7;tongue: 29.9" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 8.3;Horizontal cells: 1.7;Respiratory ciliated cells: 9.1;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 107 "basophil: 13.3;eosinophil: 8.0" "Lineage enriched" "Detected in single" 133 "granulocytes: 13.3" "Cell line enhanced" "Detected in some" "A549: 12.7;EFO-21: 23.6;HHSteC: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056615 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" Cytosol "HPA056615: AB_2683192" "unprognostic (1.83e-1)" "unprognostic (9.51e-2)" "unprognostic (7.07e-2)" "unprognostic (8.58e-2)" "unprognostic (2.89e-2)" "unprognostic (2.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.72e-1)" "unprognostic (1.53e-1)" "unprognostic (6.07e-8)" "unprognostic (9.79e-2)" "unprognostic (1.28e-1)" 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.1 0.9 0.3 0.2 0.1 0.2 0.2 0.0 0.3 8.8 0.0 0.0 0.6 0.6 0.0 0.0 2.2 0.0 1.0 2.0 0.0 0.0 2.9 1.9 0.0 0.8 0.4 0.0 0.1 1.0 0.0 90.7 0.0 0.2 0.0 1.0 0.1 0.3 2.3 0.4 0.0 0.0 29.9 0.1 0.0 0.0 0.5 0.0 12.7 0.2 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.1 1.1 0.0 23.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 5.6 0.0 0.1 0.1 0.0 0.0 0.0 1.9 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.1 1.6 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.2 0.0 2.8 0.0 0.0 0.0 3.5 0.1 0.2 0.0 0.0 13.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.9 0.6 0.6 1.0 2.0 0.8 1.0 0.4 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 8.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 9.1 0.0 0.0 2.3 0.1 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 845.6;Late spermatids: 1655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nucleoli" "HPA052636: AB_2681893, HPA056472: AB_2683143" "unprognostic (9.23e-2)" "unprognostic (8.54e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (3.07e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (4.58e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (3.16e-1)" 52.3 37.2 50.6 17.5 52.1 31.7 42.1 50.7 69.4 57.0 48.2 54.8 34.4 45.8 48.2 29.5 45.3 27.4 26.9 52.3 55.9 29.7 29.3 28.6 26.2 51.9 53.8 68.6 30.7 27.0 43.1 17.9 54.3 34.9 15.9 29.1 29.0 31.8 60.4 36.7 30.4 28.5 52.8 26.1 36.5 51.3 52.1 25.8 27.0 35.6 25.3 44.2 41.1 53.3 27.5 22.2 33.0 64.1 76.3 118.3 14.4 39.0 55.8 26.8 52.8 38.9 40.1 113.9 56.2 27.5 42.7 34.2 29.2 46.9 35.0 54.3 54.5 29.9 33.2 32.8 56.3 13.7 89.2 96.9 49.5 35.1 57.9 92.3 54.8 49.0 18.6 47.1 39.9 31.2 43.1 58.2 17.1 34.7 21.5 46.2 40.7 44.3 46.0 26.4 52.2 36.9 27.1 15.3 97.1 40.8 48.4 33.9 53.2 24.5 16.4 40.2 35.2 45.8 55.1 42.5 46.2 48.5 14.8 62.0 26.4 60.7 30.5 31.8 41.1 43.5 43.5 38.4 29.1 39.5 45.0 44.2 47.9 31.4 44.6 26.1 52.6 31.6 50.6 52.1 50.7 69.4 52.3 55.9 51.9 53.8 54.3 52.8 52.1 53.3 86.8 38.5 36.4 13.7 92.9 167.1 107.0 113.6 157.1 80.5 121.9 124.7 45.1 100.1 68.9 42.3 25.0 50.3 93.3 42.8 92.0 63.9 845.6 57.6 116.4 99.5 62.4 76.6 29.4 90.9 62.5 107.4 32.6 61.7 123.4 66.6 102.4 69.1 69.9 55.5 32.0 69.4 107.8 111.5 130.8 1655.8 168.0 76.6 96.0 10.3 126.9 127.7 90.6 15.1 18.6 67.5 58.0 132.4 55.2 148.6 158.2 199.1 51.3 71.4 98.6 119.5 109.7 241.5 68.6 119.3 201.6 73.2 101.6 67.9 90.9 107.9 CATSPERE "C1orf101, MGC33370" ENSG00000179397 "Catsper channel auxiliary subunit epsilon" Q5SY80 1 244454377-244641177 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Endometrial ciliated cells: 8.6;Respiratory ciliated cells: 8.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 83: Testis - Spermatogenesis" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.22e-1)" "unprognostic (4.50e-2)" "unprognostic (2.02e-1)" "unprognostic (7.31e-2)" "unprognostic (3.32e-1)" "unprognostic (2.50e-3)" "unprognostic (3.76e-3)" "unprognostic (5.39e-4)" "unprognostic (1.96e-2)" "unprognostic (3.41e-2)" "unprognostic (4.37e-4)" "unprognostic (4.43e-2)" "unprognostic (9.09e-2)" "unprognostic (1.76e-1)" "unprognostic (5.79e-2)" "unprognostic (6.74e-3)" "unprognostic (5.85e-2)" 0.5 0.6 1.0 0.1 1.1 0.6 0.6 0.7 0.8 0.6 0.4 0.2 0.1 0.5 2.7 0.2 1.3 0.4 0.1 0.7 0.9 0.9 0.6 0.5 0.2 1.0 1.0 0.7 0.4 0.8 1.1 0.5 1.1 0.5 0.2 0.7 0.4 0.5 0.5 0.3 0.3 0.2 1.3 0.5 0.3 21.5 1.1 0.3 0.9 0.5 0.2 0.4 0.4 1.4 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.5 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 1.1 0.7 0.8 0.7 0.9 1.0 1.0 1.1 1.3 1.1 1.4 0.7 3.2 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.0 1.3 1.8 0.0 0.2 0.1 0.0 0.0 0.4 0.0 8.6 1.1 0.1 0.0 0.0 0.0 0.6 0.2 0.3 0.0 0.8 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 8.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.8 0.0 0.0 CCDC51 FLJ12436 ENSG00000164051 "Coiled-coil domain containing 51" Q96ER9 3 48432164-48440456 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010980, HPA011408" Supported Supported Nucleoplasm,Centrosome,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Centrosome "HPA010980: AB_1846155, HPA011408: AB_2072212" "unprognostic (1.24e-2)" "unprognostic (5.23e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-1)" "unprognostic (2.75e-3)" "unprognostic (4.71e-3)" "unprognostic (1.26e-2)" "unprognostic (3.04e-1)" "unprognostic (3.26e-2)" "unprognostic (7.70e-2)" "unprognostic (1.47e-3)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" 10.1 13.7 10.7 7.3 10.9 5.0 8.7 10.8 11.6 8.3 22.2 12.2 11.0 8.0 10.1 13.8 8.8 5.4 11.9 11.1 10.6 13.9 13.0 6.7 9.6 11.3 10.8 7.7 5.4 9.4 6.1 8.2 11.3 6.7 13.6 7.7 7.0 9.0 15.5 10.1 8.6 9.0 10.7 12.6 7.6 7.8 11.7 9.9 10.3 11.7 11.8 9.0 9.5 10.7 22.7 26.7 15.7 18.7 23.1 24.2 43.6 14.6 13.4 28.6 23.2 42.9 36.9 48.6 20.5 11.7 21.6 32.2 39.5 47.8 17.4 22.9 25.6 41.4 44.1 32.7 35.3 20.4 18.2 18.4 106.8 35.6 38.8 15.7 16.7 28.0 23.4 13.7 27.7 21.4 24.1 26.5 34.8 48.2 42.8 16.5 18.6 37.7 39.3 27.8 13.1 27.2 24.2 26.2 39.9 14.7 28.2 31.3 12.6 16.5 22.3 41.6 28.5 22.0 34.8 25.5 22.0 43.8 16.0 3.0 14.1 7.0 15.5 14.9 15.8 28.1 14.5 19.7 25.5 23.0 14.8 17.4 6.0 16.5 9.1 21.1 19.8 14.6 10.7 10.9 10.8 11.6 11.1 10.6 11.3 10.8 11.3 10.7 11.7 10.7 7.1 12.8 2.6 2.6 5.9 4.7 3.7 28.8 17.6 7.3 6.6 8.1 8.2 15.7 12.8 9.2 0.0 40.1 5.0 12.6 23.5 15.1 3.3 19.4 7.3 5.9 5.4 5.9 2.4 12.4 22.0 10.0 6.6 16.5 3.8 10.1 4.6 13.1 15.9 8.4 2.4 7.6 14.2 3.8 3.3 2.7 12.2 4.4 14.2 1.9 9.1 11.0 11.3 3.5 3.2 15.2 8.0 13.2 5.1 5.4 21.6 43.4 9.3 10.7 6.6 4.0 6.2 7.2 16.3 13.0 4.7 6.7 4.8 20.0 13.4 3.4 CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.2" "Cell type enhanced" "Detected in many" "B-cells: 14.1;Bipolar cells: 12.8;Plasma cells: 62.7;Sertoli cells: 19.7;Smooth muscle cells: 16.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.4" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.4" "Cell line enhanced" "Detected in some" "Karpas-707: 8.4;RPMI-8226: 6.5;U-266/70: 17.1;U-266/84: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: AB_2680232, HPA069188: AB_2686100" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" 4.5 2.1 1.1 0.7 1.1 0.2 5.2 3.1 2.7 6.6 0.0 4.8 1.8 8.5 0.3 0.8 8.5 0.2 4.4 0.7 6.5 2.8 0.8 4.1 0.3 3.9 4.6 6.2 2.3 0.0 20.2 0.7 6.6 3.8 0.2 0.7 2.2 0.6 4.7 1.5 3.1 0.5 1.0 3.2 2.6 4.0 4.0 0.2 2.8 0.4 0.0 2.4 3.2 1.2 0.5 0.8 0.8 4.7 0.3 0.7 1.1 1.7 0.5 0.2 0.4 0.7 0.3 0.1 0.3 0.3 1.6 0.8 0.0 0.1 0.1 2.0 1.2 0.0 3.2 0.4 0.6 0.0 0.3 0.7 0.0 0.3 0.0 0.5 0.1 0.3 2.6 8.4 0.0 0.3 0.1 2.4 0.6 0.0 1.2 0.6 0.1 6.5 1.1 0.0 0.7 1.0 0.4 0.0 0.2 0.3 0.8 0.9 1.9 2.1 0.5 0.7 0.2 17.1 8.4 2.5 1.3 0.6 0.9 0.0 0.6 0.2 0.4 0.1 0.3 5.3 10.9 5.4 0.4 5.9 1.3 1.8 0.2 0.2 0.4 24.7 72.4 1.5 1.1 1.1 3.1 2.7 0.7 6.5 3.9 4.6 6.6 1.0 4.0 1.2 7.3 0.0 0.0 0.7 14.1 0.8 0.3 0.4 0.6 12.8 1.0 1.3 2.1 0.0 0.1 0.0 0.0 0.2 0.6 0.0 3.9 0.3 0.5 1.6 2.9 2.9 1.8 0.0 5.1 0.5 0.3 5.4 1.5 0.9 0.0 0.6 2.2 0.2 1.9 1.7 4.6 0.6 2.0 2.5 3.7 2.5 5.6 1.2 5.4 0.0 3.8 2.5 2.1 1.0 1.3 0.3 0.1 2.6 62.7 0.3 0.2 0.7 1.0 3.2 19.7 2.3 16.7 1.6 2.1 0.3 0.3 0.0 2.9 1.9 0.7 0.1 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 40.4;Kupffer cells: 43.1;Macrophages: 25.2;monocytes: 34.9;Plasma cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 185.5;THP-1: 89.8;U-266/70: 416.5;U-266/84: 177.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.6 1.9 0.1 25.9 0.1 1.9 3.1 0.1 0.2 1.6 0.3 4.6 7.5 1.2 0.9 1.2 1.2 3.4 1.1 0.1 0.1 1.2 2.1 5.8 11.6 0.4 0.2 1.1 0.8 0.3 0.2 0.8 0.2 1.2 5.1 0.0 3.1 1.7 0.5 1.9 5.7 7.1 0.3 20.4 5.2 1.0 0.2 4.3 1.1 0.5 7.2 5.5 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 2.7 0.0 185.5 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.3 416.5 177.7 0.0 0.1 3.3 0.1 560.9 146.2 2.6 11.9 12.8 89.2 7.9 24.3 20.2 145.2 1.8 0.6 0.7 3.8 14.0 0.4 113.6 11.4 81.6 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.2 0.3 0.2 0.3 0.1 0.0 1.3 0.0 5.8 0.3 0.0 0.0 0.6 0.0 0.1 0.1 0.3 1.5 0.0 0.0 0.0 0.1 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 4.4 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.0 1.8 0.9 0.8 0.0 0.0 0.0 0.0 43.1 10.5 0.7 0.0 25.2 0.0 0.0 34.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 8.2 0.1 0.1 0.0 CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 716.2;Exocrine glandular cells: 636.7;Pancreatic endocrine cells: 736.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" 332.4 159.5 54.0 79.7 53.5 25.0 277.8 52.5 67.6 181.6 66.1 219.7 140.6 264.6 103.0 97.5 184.3 132.4 345.8 54.2 65.3 194.3 145.3 240.1 35.4 64.5 57.4 116.2 278.3 85.9 81.1 110.1 60.5 182.9 99.8 9.6 243.5 194.2 113.1 107.0 149.4 255.2 58.3 94.8 187.3 44.8 58.6 15.0 133.5 77.0 30.6 203.1 151.3 58.0 380.0 475.3 71.8 256.3 1088.7 422.8 110.4 587.1 400.4 285.0 241.2 252.6 677.2 0.2 224.0 943.5 388.4 358.4 71.1 498.4 96.1 135.0 236.6 112.8 139.1 193.4 366.7 90.2 157.4 388.6 328.2 164.5 367.8 1089.2 348.8 16.4 135.1 56.3 485.9 196.1 1.9 99.5 48.0 232.9 569.4 20.0 173.7 106.4 642.8 102.1 99.5 111.8 578.9 371.5 121.5 81.6 145.8 102.4 600.0 462.6 209.3 147.5 352.9 62.0 66.5 4.5 437.5 89.7 265.8 24.6 19.1 15.2 5.7 19.3 6.8 3.0 4.7 5.0 11.9 2.0 1.9 3.0 7.3 8.2 24.1 1.8 2.9 10.8 54.0 53.5 52.5 67.6 54.2 65.3 64.5 57.4 60.5 58.3 58.6 58.0 294.4 208.3 79.1 13.1 12.8 70.6 143.2 328.2 60.9 16.6 180.9 203.7 180.0 133.0 159.8 248.3 4.2 222.6 15.6 542.3 19.6 716.2 2.6 60.8 114.6 214.8 127.6 28.6 10.0 636.7 423.8 173.8 236.5 143.7 81.3 103.7 265.2 54.0 130.0 37.0 5.5 388.5 138.4 59.3 70.4 11.3 123.6 81.8 128.1 15.9 75.6 94.8 23.7 3.5 0.7 736.6 477.9 283.2 26.6 307.1 440.6 124.6 52.2 17.0 210.4 96.6 310.3 5.6 13.6 73.4 54.4 185.7 29.7 61.1 289.8 199.6 CD19 ENSG00000177455 "CD19 molecule" P15391 16 28931965-28939342 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 33.0;lymphoid tissue: 75.3" "Cell type enhanced" "Detected in some" "B-cells: 135.3;Early spermatids: 38.2;Plasma cells: 30.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 80 "memory B-cell: 138.2;naive B-cell: 172.1" "Lineage enriched" "Detected in many" 89 "B-cells: 172.1" "Cell line enhanced" "Detected in some" "Daudi: 143.3;REH: 77.1;U-698: 33.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB016110 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016110: AB_626952" "unprognostic (3.27e-3)" "unprognostic (1.19e-3)" "unprognostic (6.63e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-3)" "unprognostic (3.11e-5)" "unprognostic (2.61e-1)" "unprognostic (6.96e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-6)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" 0.6 0.1 0.0 28.5 0.1 6.2 0.1 0.9 0.4 0.1 0.0 2.0 0.9 0.2 0.1 0.9 0.2 0.9 0.1 0.0 0.0 0.7 0.3 0.5 72.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 1.6 0.1 1.2 0.1 0.0 0.0 33.0 0.2 0.0 72.7 3.9 3.8 0.2 5.7 1.2 0.0 75.3 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 77.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 33.0 0.0 0.1 0.0 1.9 0.2 0.2 0.0 0.3 0.0 138.2 0.1 0.0 0.3 172.1 0.4 0.1 1.3 0.3 0.4 0.2 0.0 7.2 0.0 0.1 0.9 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.6 0.0 135.3 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 1.5 0.2 0.0 0.0 38.2 1.5 0.0 1.0 0.0 0.8 0.0 0.0 0.8 0.8 0.5 0.1 0.0 0.4 1.4 0.3 1.7 0.0 0.0 0.1 0.0 0.8 0.6 7.9 0.3 1.1 3.6 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.1 0.7 30.5 0.2 0.3 0.1 0.5 0.1 0.0 0.1 0.1 7.4 4.2 0.0 0.0 0.7 2.4 0.6 0.5 0.1 CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 97.4;Excitatory neurons: 54.5;Inhibitory neurons: 55.7;Syncytiotrophoblasts: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.7;naive B-cell: 83.6" "Lineage enriched" "Detected in many" 23 "B-cells: 83.6" "Cell line enhanced" "Detected in some" "AF22: 75.9;HHSteC: 27.2;NTERA-2: 47.7;REH: 42.4;SK-MEL-30: 29.8;WM-115: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" 25.3 12.1 27.7 15.6 27.3 2.4 11.6 13.2 34.0 20.1 2.9 6.7 3.3 28.4 7.1 8.9 26.7 13.1 9.3 27.9 41.3 8.5 1.0 9.6 26.1 11.9 16.3 11.6 4.9 10.5 26.8 28.2 18.8 12.1 8.2 15.1 9.0 16.5 1.8 4.4 6.9 18.3 15.1 6.2 5.2 2.9 30.4 23.6 18.9 3.6 24.9 27.5 5.9 18.3 0.0 0.0 75.9 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.1 0.0 0.9 0.1 8.2 0.4 0.2 0.2 0.5 0.0 0.3 0.4 27.2 0.0 0.1 0.5 0.2 1.6 0.2 0.2 10.8 0.0 0.1 0.7 0.2 0.0 1.2 0.0 47.7 0.0 0.0 42.4 0.1 0.5 0.6 0.1 19.9 23.0 0.0 0.4 29.8 14.0 0.0 0.3 0.1 0.3 2.6 0.0 0.2 0.1 0.1 0.0 0.6 0.2 83.7 3.6 0.4 0.3 0.3 0.1 3.5 30.7 2.0 0.6 1.3 83.6 2.1 1.3 1.7 1.6 0.3 2.8 1.0 3.4 27.7 27.3 13.2 34.0 27.9 41.3 11.9 16.3 18.8 15.1 30.4 18.3 15.2 3.2 9.1 10.7 27.8 4.2 12.6 0.3 0.0 26.8 0.7 13.0 0.8 1.5 1.3 1.8 0.0 3.0 1.6 0.8 0.0 0.3 25.1 20.6 4.2 97.4 38.4 0.8 54.5 0.0 12.1 13.0 3.1 41.0 2.5 0.7 1.4 0.0 1.0 3.3 55.7 8.1 0.0 0.3 6.1 30.3 0.3 1.1 8.8 6.5 14.0 7.1 0.0 29.7 38.5 0.2 10.7 0.0 1.9 15.4 0.9 0.3 2.7 2.5 0.0 13.1 2.6 0.6 0.4 0.7 3.3 75.9 2.9 9.3 7.1 21.6 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 280.3;Proximal enterocytes: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 536.4" "Group enriched" "Detected in all" 6 "B-cells: 310.1;granulocytes: 536.4;T-cells: 173.1" "Cell line enhanced" "Detected in many" "HMC-1: 463.8;U-87 MG: 323.3" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" 39.2 9.1 47.7 57.3 80.5 140.9 36.6 45.2 48.8 38.8 48.5 24.7 74.1 9.1 31.9 130.9 54.0 39.6 25.6 41.9 51.7 26.1 36.9 87.3 68.5 58.5 74.3 14.9 31.3 7.8 7.5 41.0 49.8 27.5 17.2 4.2 81.1 72.1 23.1 84.2 81.6 16.6 39.6 47.3 62.8 4.5 79.0 45.0 22.4 20.0 82.6 47.6 66.1 67.2 30.0 5.2 35.1 7.2 24.0 98.4 1.2 16.9 132.9 29.4 78.5 2.0 19.6 30.9 20.8 8.1 61.1 118.8 4.6 88.4 59.6 145.4 2.7 220.9 9.3 0.6 21.3 58.8 463.8 142.1 99.2 128.3 62.1 68.4 49.7 26.9 1.6 9.4 247.3 25.0 46.7 97.7 1.1 103.2 2.4 1.5 190.0 43.9 16.8 36.1 1.2 2.0 13.0 162.6 23.0 4.2 161.2 51.3 33.9 94.4 12.5 1.8 179.0 3.6 0.4 0.9 323.3 32.5 56.0 369.9 59.3 110.7 29.9 33.0 51.4 310.1 150.7 70.3 14.9 211.9 51.1 23.1 536.4 50.1 25.0 44.5 173.1 65.9 47.7 80.5 45.2 48.8 41.9 51.7 58.5 74.3 49.8 39.6 79.0 67.2 43.6 48.1 38.8 9.4 112.8 55.1 108.1 149.0 107.6 2.4 68.1 54.7 7.7 58.6 143.8 158.2 2.1 1.3 14.9 17.4 11.7 79.7 2.0 23.1 5.0 41.0 13.2 92.9 0.3 66.7 1.1 29.1 58.6 25.2 280.3 0.7 59.6 32.5 64.3 1.7 0.6 36.8 63.1 26.6 18.2 2.0 40.4 52.3 64.0 3.7 11.0 35.7 0.0 54.3 22.4 86.7 50.3 8.2 16.0 59.1 220.6 2.5 73.0 2.7 13.1 109.0 46.0 2.1 5.9 161.3 67.2 1.4 46.3 0.6 43.1 142.8 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CDC14C "CDC14B2, CDC14Bretro, CDC14CP, MGC26484" ENSG00000218305 "Cell division cycle 14C" A4D256 7 48919765-48927454 "Enzymes, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.0;testis: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Oligodendrocyte precursor cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064747 Uncertain Nucleoplasm NA NA "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA064747: AB_2732719" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" 0.1 0.0 0.3 0.2 0.3 0.4 0.1 0.9 0.4 0.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.1 0.2 0.3 0.1 0.2 0.0 0.1 0.2 0.1 0.1 2.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.1 7.2 0.5 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.2 0.2 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.2 0.0 0.3 0.3 0.9 0.4 0.5 0.4 0.2 0.3 0.2 0.0 0.5 0.4 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 732.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" 95.0 307.2 126.3 53.1 171.3 80.1 100.1 170.2 165.7 96.8 141.7 81.5 94.5 79.9 89.6 46.2 94.1 97.1 71.8 125.5 144.8 261.4 732.2 135.0 56.4 201.5 168.5 104.4 129.3 159.4 84.7 113.8 192.1 83.2 88.6 38.1 61.5 82.7 37.5 46.9 102.8 99.2 158.7 65.1 128.0 49.8 157.2 67.5 161.4 57.3 69.9 91.0 70.7 223.7 154.3 175.8 138.1 277.9 395.1 237.1 100.8 153.1 217.9 278.1 189.1 188.4 248.5 137.7 244.3 242.4 174.6 165.5 195.5 160.7 247.6 194.0 157.7 193.4 107.5 219.3 277.6 216.4 218.5 214.0 197.9 254.3 315.6 341.4 174.3 189.8 210.4 281.0 363.4 255.6 134.2 135.7 200.9 499.4 299.6 160.0 95.4 208.4 311.5 127.2 121.7 185.8 169.6 278.7 183.8 172.1 335.6 296.5 145.4 196.4 93.6 180.1 267.9 189.5 229.0 841.7 222.4 91.0 200.7 212.1 80.2 136.0 76.9 43.7 93.6 34.6 70.3 78.8 69.5 31.9 60.6 60.1 86.5 63.4 32.8 70.1 86.7 88.5 126.3 171.3 170.2 165.7 125.5 144.8 201.5 168.5 192.1 158.7 157.2 223.7 46.3 67.3 67.9 8.8 23.1 24.1 38.2 37.0 18.2 7.5 52.8 27.6 2.8 120.1 23.2 53.3 4.2 77.8 40.2 60.7 13.7 104.6 7.5 24.9 39.9 47.9 24.6 24.8 5.5 92.8 42.4 44.2 16.3 29.7 36.8 33.0 38.9 200.5 55.9 3.3 5.9 29.3 30.5 45.2 35.2 7.9 56.2 54.5 37.4 5.6 39.4 26.5 26.8 7.5 51.3 103.7 32.4 40.3 29.2 52.4 98.8 81.7 21.2 9.9 39.5 37.2 33.8 13.8 6.8 13.9 15.6 54.2 34.3 39.0 29.1 34.2 CERS3 "LASS3, MGC27091" ENSG00000154227 "Ceramide synthase 3" Q8IU89 15 100400395-100544995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 55.1;skin 1: 64.0;vagina: 30.3" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 39.3;Early spermatids: 23.5;Late spermatids: 17.5;Spermatocytes: 28.2;Squamous epithelial cells: 48.3;Suprabasal keratinocytes: 50.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 14.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 65.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006092, HPA024356" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA006092: AB_1079236, HPA024356: AB_1852721" "unprognostic (5.01e-3)" "unprognostic (3.43e-2)" "unprognostic (6.47e-4)" "unprognostic (2.35e-2)" "unprognostic (5.58e-2)" "unprognostic (1.68e-1)" "unprognostic (6.84e-3)" "unprognostic (3.23e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (1.31e-5)" "unprognostic (2.65e-1)" "unprognostic (4.74e-4)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" 0.1 0.0 0.1 0.0 0.2 0.2 3.3 0.3 0.2 15.1 0.0 0.0 0.0 0.0 0.5 55.1 0.7 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.6 0.0 0.1 8.4 0.1 0.6 64.0 0.1 0.0 0.0 0.1 0.1 18.3 0.2 0.4 0.1 0.0 16.0 0.3 30.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 1.3 0.0 18.9 5.0 3.9 39.3 0.4 0.1 0.3 0.5 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.5 0.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.1 17.5 0.6 0.1 0.0 0.0 0.0 0.2 0.0 2.0 1.4 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 28.2 0.7 48.3 50.2 0.0 0.1 0.0 0.0 6.0 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CHML REP-2 ENSG00000203668 "CHM like Rab escort protein" P26374 1 241628851-241640369 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029627, HPA029628, HPA062967" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 9: U-2 OS - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA029627: AB_2756314, HPA029628: AB_10603784, HPA062967: AB_2797269" "unprognostic (1.63e-1)" "unprognostic (6.84e-2)" "unprognostic (3.57e-1)" "unprognostic (8.00e-2)" "unprognostic (2.46e-1)" "unprognostic (5.66e-2)" "prognostic unfavorable (9.23e-5)" "unprognostic (1.90e-2)" "unprognostic (3.37e-2)" "unprognostic (8.01e-3)" "unprognostic (3.02e-3)" "unprognostic (3.68e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.03e-3)" "unprognostic (1.09e-1)" 2.7 1.8 0.7 3.5 1.5 7.5 3.6 0.0 3.6 3.1 0.0 3.0 2.2 4.2 2.7 3.3 2.8 3.2 3.0 1.5 0.2 2.9 2.4 3.8 3.7 0.1 1.0 7.4 2.0 4.1 1.5 11.4 0.0 1.9 3.4 3.3 2.3 1.5 2.6 3.2 2.8 3.2 0.0 3.9 3.1 6.1 1.7 6.4 4.4 3.4 3.0 2.1 2.3 1.5 31.3 9.5 14.6 11.7 4.3 12.8 28.4 12.1 6.0 10.3 7.0 17.5 5.6 8.6 18.1 8.1 8.4 6.3 20.6 13.1 19.0 16.5 19.2 11.3 39.4 12.3 8.7 27.2 14.0 10.7 5.8 13.6 14.0 7.2 8.2 22.7 31.0 10.2 12.3 12.2 18.1 18.1 19.4 11.8 30.6 27.3 18.0 28.8 10.4 19.2 18.6 30.6 15.2 11.5 13.3 14.2 13.5 17.4 16.7 20.9 40.8 10.6 23.3 11.9 31.2 9.0 20.3 16.0 33.0 1.1 0.2 0.1 0.1 0.3 0.1 0.3 0.0 0.0 0.2 0.3 0.3 0.2 0.0 0.1 0.2 0.7 0.0 0.0 0.7 1.5 0.0 3.6 1.5 0.2 0.1 1.0 0.0 0.0 1.7 1.5 14.0 48.1 7.0 0.0 17.2 8.5 6.1 3.8 3.4 3.6 9.9 11.7 19.6 4.3 7.9 0.0 0.0 23.5 26.4 6.2 5.9 14.8 12.3 14.4 15.1 8.1 6.7 10.3 0.0 21.3 26.7 6.5 6.6 34.8 3.8 21.3 4.2 2.1 7.1 5.0 0.0 4.2 6.1 17.6 31.0 30.9 10.5 34.7 17.8 0.0 18.6 3.1 4.1 0.0 0.0 22.5 4.3 18.0 5.8 3.9 4.3 2.2 2.0 4.7 13.1 11.4 20.7 9.0 12.6 7.6 7.2 20.1 5.8 9.9 5.0 4.3 CHRNA7 ENSG00000175344 "Cholinergic receptor nicotinic alpha 7 subunit" P36544 15 31923438-32173018 "FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.8;intestine: 9.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 9.0;Gastric mucus-secreting cells: 26.0;Horizontal cells: 16.8;Inhibitory neurons: 30.7;Proximal enterocytes: 14.4" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.3;RT4: 12.9;SH-SY5Y: 8.3;SK-BR-3: 13.3;U-2 OS: 10.8" "HPA029422, CAB033624" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB033624: AB_784835, HPA029422: AB_10600863" "unprognostic (3.43e-2)" "unprognostic (8.44e-2)" "unprognostic (2.02e-1)" "unprognostic (4.61e-4)" "unprognostic (6.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.14e-2)" "unprognostic (5.08e-2)" "unprognostic (1.63e-1)" "unprognostic (4.31e-2)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-2)" "unprognostic (4.36e-3)" "unprognostic (5.44e-2)" "unprognostic (7.41e-3)" "unprognostic (2.43e-1)" 0.3 7.8 1.2 0.4 1.1 0.9 1.0 1.8 1.8 0.4 2.1 1.5 4.4 0.5 0.3 0.3 0.4 0.9 0.5 1.0 4.5 0.4 0.1 0.5 0.7 4.5 3.9 1.6 2.4 6.4 1.0 0.0 7.0 1.2 2.3 2.5 0.5 0.7 0.5 0.3 9.7 0.4 1.5 1.2 6.6 2.5 3.3 0.4 2.2 0.8 0.7 1.5 0.7 1.1 0.0 1.3 2.7 6.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 3.1 0.0 0.0 0.0 1.7 0.6 0.0 2.2 0.0 0.4 1.0 0.0 0.0 0.2 0.0 0.1 0.4 2.5 0.0 0.2 0.3 0.2 0.0 0.2 1.5 3.7 0.0 0.0 4.2 0.3 0.5 12.9 0.5 8.3 0.2 13.3 0.0 0.7 0.0 0.5 1.2 0.0 10.8 0.3 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.2 1.1 1.8 1.8 1.0 4.5 4.5 3.9 7.0 1.5 3.3 1.1 0.5 0.0 0.0 1.0 0.0 0.3 3.0 0.0 7.4 1.8 1.1 1.3 1.1 2.8 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.3 0.1 0.2 0.3 1.5 3.0 0.0 9.0 2.5 0.0 0.4 26.0 0.6 1.3 4.6 0.7 0.0 0.1 16.8 30.7 8.9 0.0 0.0 0.9 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.5 1.1 1.6 2.9 0.0 0.2 0.7 14.4 0.2 0.0 0.0 0.0 0.4 0.3 0.2 5.9 3.2 0.0 0.0 0.1 0.2 2.0 1.2 CHRNB1 CHRNB ENSG00000170175 "Cholinergic receptor nicotinic beta 1 subunit" P11230 17 7445061-7457710 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.4;tongue: 57.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.0;Skeletal myocytes: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 34.6;RH-30: 71.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005822, CAB011200" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB011200: AB_262151, HPA005822: AB_1079484" "unprognostic (2.89e-2)" "unprognostic (3.43e-1)" "unprognostic (1.08e-1)" "unprognostic (2.67e-2)" "unprognostic (4.19e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-2)" "unprognostic (3.56e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" "unprognostic (2.49e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" 7.0 30.6 6.9 2.4 7.8 9.1 6.7 7.3 7.5 7.5 8.8 6.3 2.9 6.6 5.1 7.0 5.4 1.9 11.5 6.9 6.9 10.7 16.5 5.1 3.6 7.5 7.0 5.4 16.5 9.1 6.7 6.7 7.3 5.1 2.5 3.2 10.7 3.0 158.4 8.1 5.5 3.2 7.3 7.9 5.2 3.2 7.1 6.5 13.0 57.7 3.9 5.5 7.2 8.1 1.6 2.2 3.8 4.5 6.0 4.0 8.6 1.1 3.8 5.6 4.6 1.3 2.0 6.2 4.0 2.5 2.0 13.6 1.4 25.1 2.0 7.6 4.8 3.5 2.3 8.1 2.6 2.2 8.6 8.8 6.8 3.4 11.0 9.3 3.8 12.0 4.6 3.4 34.6 1.0 6.7 4.1 2.7 1.5 1.1 4.4 71.0 15.8 15.3 1.2 0.6 11.1 2.4 4.0 4.7 5.9 3.9 3.0 3.6 2.3 6.4 1.7 5.0 8.1 9.6 1.7 2.1 4.9 2.1 9.9 5.4 13.6 7.9 6.3 6.1 6.7 8.7 8.0 7.0 7.0 7.0 9.2 1.7 11.0 10.4 5.2 7.9 6.1 6.9 7.8 7.3 7.5 6.9 6.9 7.5 7.0 7.3 7.3 7.1 8.1 8.8 0.0 4.8 4.6 8.9 6.4 3.8 12.6 6.2 3.9 9.3 11.2 9.8 4.3 7.2 9.2 2.1 39.0 17.7 5.2 23.5 16.1 2.2 5.1 7.1 10.1 2.4 3.4 1.4 13.4 9.4 8.1 3.6 7.1 13.3 5.8 10.4 10.8 12.6 15.2 1.5 4.8 14.2 7.2 8.7 2.1 21.8 7.9 12.4 1.0 17.0 14.0 29.9 1.0 5.6 17.3 4.9 17.0 5.8 4.1 10.2 15.5 9.5 7.1 0.0 47.3 8.1 2.8 2.8 6.1 6.5 30.4 11.2 12.1 5.9 3.8 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CKLF-CMTM1 ENSG00000254788 "CKLF-CMTM1 readthrough" 16 66552587-66579135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 5.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Early spermatids: 3.9;granulocytes: 20.2;Late spermatids: 8.9;Respiratory ciliated cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 17.4" HPA017136 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 60: Granulocytes - Receptor signaling" "HPA017136: AB_1846992" "unprognostic (9.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (1.66e-2)" "unprognostic (2.19e-2)" "unprognostic (9.65e-2)" "unprognostic (5.90e-3)" "unprognostic (3.16e-2)" "unprognostic (1.73e-1)" "unprognostic (9.69e-2)" "unprognostic (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (2.98e-2)" "unprognostic (7.51e-2)" "unprognostic (4.45e-2)" "unprognostic (2.12e-1)" "unprognostic (1.44e-1)" 0.8 0.8 1.5 2.9 1.6 0.8 0.7 1.8 1.8 1.1 0.7 1.1 0.8 1.8 1.1 0.9 1.4 1.5 1.0 1.7 2.3 1.1 0.5 1.4 1.6 1.8 1.4 1.9 1.4 1.0 1.0 1.3 1.9 0.8 0.6 0.9 0.7 0.8 0.2 0.7 1.7 1.0 1.1 2.0 1.1 5.7 1.8 3.3 1.1 0.3 1.0 0.8 0.9 1.7 4.7 5.9 2.3 5.6 2.6 5.1 0.8 5.4 2.9 4.6 7.0 2.1 4.9 1.8 2.9 0.6 1.4 3.5 2.8 0.3 3.0 5.3 1.5 0.4 1.9 0.2 1.9 4.0 3.0 0.2 0.3 2.7 0.6 8.3 2.7 6.3 2.1 5.0 3.6 1.4 9.1 5.0 1.4 0.6 2.4 17.4 8.2 5.9 4.1 1.3 3.5 4.9 9.4 0.6 1.7 0.2 2.2 2.1 1.9 6.3 11.3 4.5 2.0 3.0 6.6 7.1 4.1 4.0 10.5 9.8 4.1 11.8 2.8 1.7 3.0 0.4 1.1 1.8 3.6 0.7 0.5 1.4 12.9 2.0 2.1 1.4 4.0 3.0 1.5 1.6 1.8 1.8 1.7 2.3 1.8 1.4 1.9 1.1 1.8 1.7 0.0 3.2 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.2 3.9 0.0 0.1 0.1 0.0 0.4 0.0 0.2 0.1 0.2 0.0 0.0 20.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 8.9 0.3 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108927361-108963504 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA009087: AB_1078532, HPA013210: AB_1846895" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.45e-1)" "unprognostic (5.30e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (7.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-1)" "unprognostic (4.68e-3)" "unprognostic (9.65e-2)" 14.6 16.5 10.1 11.4 14.3 6.1 16.3 10.6 11.7 17.0 7.8 15.4 13.2 17.0 24.3 9.9 15.1 14.0 18.3 10.7 11.5 11.0 22.2 13.0 10.5 12.8 10.9 18.6 24.8 21.3 18.3 17.7 12.1 20.2 13.2 11.8 22.3 20.0 27.2 10.3 12.7 14.9 11.0 11.5 16.1 7.6 11.8 5.2 21.9 24.8 10.8 15.2 13.4 16.0 44.2 22.3 25.1 45.8 36.7 33.9 35.6 43.8 34.2 30.1 34.2 22.6 21.0 10.8 43.7 33.3 18.5 17.1 23.9 16.1 39.4 38.0 23.2 30.4 24.7 23.5 28.9 28.7 28.2 25.2 21.9 33.2 25.7 28.3 27.1 12.1 38.6 47.7 22.1 18.9 2.3 10.1 21.5 16.6 19.8 24.5 13.1 31.2 24.3 30.5 15.9 22.7 46.9 49.6 38.9 18.9 15.9 19.7 26.7 38.3 27.7 35.1 38.4 32.1 33.3 17.1 44.7 21.8 82.5 4.1 5.6 6.1 5.6 8.4 6.1 6.1 4.5 4.4 5.6 3.2 4.9 4.5 1.4 4.7 12.4 6.4 6.8 4.4 10.1 14.3 10.6 11.7 10.7 11.5 12.8 10.9 12.1 11.0 11.8 16.0 13.3 25.6 20.9 26.8 11.8 3.7 14.0 11.7 1.8 12.3 11.8 9.1 5.9 20.0 18.0 11.0 29.2 28.7 9.0 7.1 0.0 18.6 6.7 8.1 21.3 10.9 3.6 5.9 25.0 21.1 12.8 19.5 10.7 13.5 12.0 16.3 9.7 22.3 13.1 21.9 30.3 9.0 16.2 6.7 5.1 2.8 19.9 9.3 8.8 14.0 12.0 11.4 3.1 35.7 39.3 17.7 3.8 18.8 17.7 17.7 7.2 5.0 14.9 18.9 19.7 18.6 10.7 5.5 5.4 6.4 6.3 18.5 8.4 12.5 9.8 9.9 CLDN12 ENSG00000157224 "Claudin 12" P56749 7 90383721-90513402 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Early spermatids: 354.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026945 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA026945: AB_10603786" "unprognostic (1.45e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (3.84e-2)" "unprognostic (4.87e-2)" "unprognostic (7.28e-2)" "unprognostic (1.86e-2)" "unprognostic (6.47e-2)" "unprognostic (3.41e-2)" "unprognostic (3.67e-1)" "unprognostic (9.06e-2)" "unprognostic (1.67e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (7.66e-2)" "unprognostic (2.37e-1)" "unprognostic (9.49e-2)" "unprognostic (1.30e-1)" 8.3 21.9 16.1 7.0 18.1 3.2 21.1 19.0 22.0 13.7 17.2 22.2 18.7 14.0 19.8 11.9 15.4 19.0 18.6 15.8 20.7 24.1 52.0 12.1 2.0 16.0 16.9 20.5 14.6 21.6 22.5 10.2 16.4 24.1 23.9 31.4 19.7 12.4 17.3 8.3 21.3 13.2 15.4 4.6 21.6 12.8 18.4 5.7 17.1 23.0 5.1 15.8 10.4 15.7 25.5 22.6 26.3 17.8 27.1 22.2 14.3 30.3 33.6 19.9 33.2 21.7 65.0 4.1 24.1 18.2 43.9 21.2 23.4 27.9 39.8 6.0 22.1 2.5 19.9 23.8 26.8 5.1 2.8 27.8 29.7 33.3 52.3 35.9 10.5 5.0 14.8 14.3 30.0 12.1 6.8 12.0 44.7 32.6 14.4 3.4 37.9 6.2 31.0 17.0 21.4 39.1 16.8 15.6 51.7 42.1 18.2 16.4 25.8 46.6 29.2 36.6 33.5 7.8 8.1 0.6 33.1 3.6 24.0 0.0 0.2 0.0 0.3 0.3 0.3 0.3 0.6 0.1 1.0 0.1 0.2 0.3 0.0 0.0 0.0 0.3 0.5 0.2 16.1 18.1 19.0 22.0 15.8 20.7 16.0 16.9 16.4 15.4 18.4 15.7 3.6 32.1 10.3 21.2 0.9 9.8 14.8 23.5 8.6 34.5 21.8 10.9 15.7 20.0 23.4 18.4 20.9 8.7 0.7 19.1 7.9 18.9 354.5 13.4 9.5 4.8 16.7 1.3 35.9 41.0 10.0 13.8 10.7 18.1 0.0 5.7 8.6 51.2 7.2 20.2 33.4 18.8 18.3 0.8 5.7 31.2 10.5 2.8 19.6 9.4 2.7 49.6 1.0 28.1 3.9 32.3 13.0 10.5 3.3 48.7 13.4 26.4 36.3 20.9 13.1 8.4 10.1 22.3 6.7 11.9 10.9 5.1 1.6 5.0 18.7 51.8 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 1093.8;choroid plexus: 316.7" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 575.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA029841: AB_10600658" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.13e-2)" "unprognostic (8.50e-2)" "unprognostic (9.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.43e-3)" "unprognostic (4.08e-2)" "unprognostic (3.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.84e-6)" "unprognostic (5.73e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.51e-1)" 53.6 42.6 477.0 40.7 757.5 49.1 48.8 696.1 804.5 59.0 316.7 58.3 36.5 58.8 43.1 77.8 46.7 50.6 57.6 483.5 577.6 39.2 50.0 46.9 54.7 851.3 670.8 63.9 23.6 32.6 28.2 73.8 837.8 49.5 46.9 46.5 29.8 51.9 43.6 64.8 42.2 63.5 643.7 44.0 37.4 106.6 638.3 44.7 40.5 68.9 54.9 64.0 65.8 1093.8 67.3 26.2 83.2 50.7 96.0 75.0 44.6 52.0 69.8 71.0 97.8 52.7 66.9 33.7 69.1 49.4 134.3 90.4 61.6 39.9 124.3 79.3 27.5 68.3 18.6 48.1 76.2 62.7 67.3 88.4 207.6 54.0 58.7 77.6 79.1 64.7 35.4 100.6 102.9 33.4 47.8 42.8 75.1 28.7 55.9 31.9 110.6 43.4 67.7 30.0 30.1 82.6 74.6 24.4 108.5 110.5 24.5 52.8 75.1 94.6 86.2 65.3 69.3 130.8 59.8 53.9 154.9 61.0 125.2 179.8 91.0 103.9 102.1 55.4 193.5 101.5 190.3 187.1 98.9 99.3 76.6 78.1 70.2 274.0 56.7 63.9 399.7 155.1 477.0 757.5 696.1 804.5 483.5 577.6 851.3 670.8 837.8 643.7 638.3 1093.8 83.3 35.3 36.6 17.9 72.1 144.0 131.7 122.3 87.0 20.1 43.6 45.3 53.8 17.2 71.4 27.6 25.0 52.0 72.8 16.9 29.4 21.2 105.3 21.1 47.7 70.8 28.7 65.4 25.1 16.2 160.6 86.6 30.1 41.7 36.8 25.2 61.4 19.4 35.6 15.2 23.6 19.6 89.5 29.2 168.1 76.7 51.6 46.9 113.8 20.6 42.3 28.1 38.1 30.7 575.2 30.3 16.8 46.6 131.7 98.1 34.6 23.3 27.5 35.0 52.6 53.2 128.4 182.4 55.3 90.1 196.5 95.8 147.1 22.8 17.5 121.9 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLECL1 DCAL1 ENSG00000184293 "C-type lectin like 1" Q8IZS7 12 9715860-9733299 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 9.9;lymphoid tissue: 31.1" "Group enriched" "Detected in some" 4 "B-cells: 87.0;dendritic cells: 24.0;Hofbauer cells: 22.2;Kupffer cells: 82.3;Langerhans cells: 64.6;Macrophages: 23.9;monocytes: 55.9;Plasma cells: 42.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 120.9" "Lineage enriched" "Detected in many" 5 "B-cells: 120.9" "Group enriched" "Detected in some" 5 "HEL: 49.7;Karpas-707: 66.2;U-698: 173.0;U-937: 95.6" "Low region specificity" "Detected in many" HPA063928 Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Centriolar satellite" "HPA063928: " "unprognostic (2.18e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-3)" "unprognostic (1.90e-3)" "unprognostic (3.66e-1)" "unprognostic (1.90e-3)" "unprognostic (2.83e-1)" "unprognostic (7.55e-4)" "unprognostic (5.10e-2)" "unprognostic (2.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-5)" "unprognostic (3.31e-1)" "unprognostic (2.45e-1)" "unprognostic (6.10e-2)" "unprognostic (7.39e-2)" 1.0 1.6 0.6 9.9 0.9 1.9 2.0 1.4 0.9 0.9 1.3 3.0 2.7 0.9 0.0 0.7 0.8 2.5 0.4 0.6 0.9 0.7 2.1 2.1 24.8 1.8 1.1 0.5 0.2 0.3 0.3 0.7 1.4 0.7 4.3 0.1 1.3 0.5 0.1 0.4 9.9 1.8 1.2 16.2 4.5 0.9 1.1 5.2 0.6 0.2 31.1 3.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.1 0.2 1.2 173.0 0.0 95.6 0.0 2.4 7.9 0.4 4.5 14.4 0.1 120.9 3.9 9.7 18.7 54.3 0.2 1.4 0.3 0.3 15.5 25.4 0.2 5.2 0.6 0.9 1.4 0.9 0.6 0.9 1.8 1.1 1.4 1.2 1.1 1.6 0.3 0.0 0.0 0.0 87.0 2.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.8 0.0 0.0 0.1 24.0 0.1 0.0 0.0 1.0 0.1 0.1 0.3 0.0 4.4 0.0 0.2 0.1 0.6 0.0 0.1 5.1 0.0 0.4 0.4 22.2 0.0 0.0 0.2 0.0 82.3 64.6 1.4 0.3 23.9 12.4 1.0 55.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 6.6 0.1 0.1 0.0 0.2 0.1 1.8 0.3 11.2 0.0 0.0 0.1 CLN6 "FLJ20561, HsT18960, nclf" ENSG00000128973 "CLN6 transmembrane ER protein" Q9NWW5 15 68206992-68257211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.8;Hofbauer cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066046, HPA066759" Approved Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Endoplasmic reticulum" "Nucleoli, Vesicles" "HPA066046: AB_2685604, HPA066759: " "unprognostic (1.01e-1)" "unprognostic (1.54e-3)" "unprognostic (7.01e-2)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (3.08e-1)" "unprognostic (2.24e-2)" "unprognostic (5.07e-2)" "unprognostic (2.40e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-1)" "unprognostic (6.78e-2)" 11.6 17.6 12.7 14.8 13.0 29.9 11.5 13.3 14.9 11.0 13.2 17.5 14.6 9.8 6.8 16.9 9.8 9.6 9.3 12.1 12.6 20.0 22.7 13.2 16.2 13.3 13.1 6.8 19.1 10.4 10.1 11.6 13.8 12.4 14.9 11.8 14.8 9.2 17.0 14.7 14.6 10.4 12.8 20.7 13.3 10.9 13.0 11.6 12.9 7.3 16.7 10.7 9.6 14.5 38.2 93.1 23.9 33.9 14.5 11.8 57.1 35.3 17.0 42.8 34.9 72.1 60.5 57.6 17.2 21.4 31.7 69.5 69.8 34.5 17.0 38.5 82.3 84.3 66.1 54.3 29.7 95.6 58.1 20.8 11.4 34.7 23.7 9.0 29.1 33.1 56.9 116.0 33.6 103.8 44.0 69.4 57.1 67.3 38.3 42.1 71.8 80.6 36.2 97.0 48.2 20.0 39.5 61.7 34.3 18.0 33.1 95.5 19.3 48.1 55.7 35.8 127.2 81.3 97.3 47.4 30.0 115.4 47.6 0.0 8.8 0.6 3.0 13.0 4.0 2.9 2.2 4.3 5.2 2.3 2.8 1.3 10.5 2.0 16.1 4.4 2.3 3.5 12.7 13.0 13.3 14.9 12.1 12.6 13.3 13.1 13.8 12.8 13.0 14.5 1.4 9.6 6.9 7.2 13.4 20.1 22.0 13.9 14.8 181.8 2.0 1.9 27.4 10.0 9.6 5.5 16.7 42.8 7.1 22.7 0.0 3.3 0.4 1.0 4.8 9.7 15.1 32.8 8.9 1.8 58.4 9.1 8.2 1.4 8.9 5.6 11.0 21.9 88.4 21.9 8.1 20.5 16.2 24.2 14.0 1.4 9.0 11.3 19.6 8.4 12.9 16.9 11.3 5.0 10.2 3.6 26.0 8.2 33.4 23.7 15.6 2.1 3.3 32.7 6.6 7.5 5.6 1.0 19.5 21.1 14.1 21.8 9.5 5.3 35.6 16.3 CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 136.8;Syncytiotrophoblasts: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" 5.4 5.2 11.4 3.7 15.7 9.1 4.3 14.6 12.4 4.7 6.6 4.9 5.0 3.2 11.2 9.8 3.3 7.5 6.2 10.6 11.3 6.2 8.9 8.9 6.5 18.2 15.2 2.5 10.1 8.0 3.5 6.0 18.5 3.8 4.4 3.8 5.1 3.6 5.9 13.2 6.3 4.0 16.9 7.9 6.8 5.9 15.1 3.2 5.1 3.3 7.2 4.4 5.8 24.3 3.6 8.5 6.2 6.5 8.3 8.4 14.8 8.3 5.1 4.2 5.2 8.6 10.0 4.4 2.3 8.2 5.6 13.7 4.9 15.6 8.6 3.3 3.6 4.4 3.2 4.9 4.7 3.7 19.1 8.4 12.2 5.8 4.1 10.1 9.2 3.2 6.0 2.6 13.1 9.0 6.0 3.2 6.1 14.0 7.3 4.2 4.3 3.4 7.8 15.4 3.2 3.9 3.5 8.1 4.6 12.7 16.2 4.2 17.3 11.3 3.2 0.9 5.2 1.5 5.4 5.0 11.4 7.3 16.9 7.4 10.6 4.7 6.4 13.6 7.1 10.3 6.9 4.5 10.6 14.0 6.7 4.4 3.7 5.1 12.5 76.7 8.0 6.4 11.4 15.7 14.6 12.4 10.6 11.3 18.2 15.2 18.5 16.9 15.1 24.3 18.3 9.6 17.5 6.2 30.1 54.7 71.6 38.6 26.7 27.6 23.4 13.2 7.7 20.0 37.2 31.3 31.3 38.0 115.3 28.5 15.6 27.2 5.4 20.5 6.9 34.7 19.7 40.8 7.4 19.0 18.0 32.7 13.7 37.2 27.3 17.1 27.8 28.5 44.1 40.4 7.6 17.5 50.8 54.6 136.8 5.9 8.1 69.8 21.4 8.4 22.3 13.9 23.7 10.1 27.1 19.3 20.7 12.0 9.1 76.5 19.5 10.6 27.1 26.1 13.1 22.5 16.8 34.4 23.5 20.1 63.5 131.6 22.0 16.1 15.4 61.2 CLRN1 "RP61, USH3, USH3A" ENSG00000163646 "Clarin 1" P58418 3 150926163-150972727 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 4.9;retina: 12.8" "Cell type enriched" "Detected in some" 6 "Muller glia cells: 165.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "NTERA-2: 3.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.00e-3)" "unprognostic (1.26e-1)" "unprognostic (5.54e-1)" "unprognostic (9.68e-2)" 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CMTM1 "CKLFH, CKLFH1a, CKLFSF1" ENSG00000089505 "CKLF like MARVEL transmembrane domain containing 1" Q8IZ96 16 66566393-66579137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 31.3" "Group enriched" "Detected in some" 4 "Early spermatids: 75.5;Late spermatids: 144.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 8.7;eosinophil: 6.2;neutrophil: 7.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.7" "Cell line enhanced" "Detected in many" "REH: 19.8" "HPA013801, HPA017136" Uncertain Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA013801: AB_1846990, HPA017136: AB_1846992" "unprognostic (2.37e-2)" "unprognostic (7.48e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-1)" "unprognostic (3.81e-1)" "unprognostic (5.32e-2)" "unprognostic (2.97e-3)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (2.47e-2)" "unprognostic (1.56e-4)" "unprognostic (1.06e-1)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (3.49e-1)" 1.0 1.1 1.0 2.5 1.0 0.3 0.5 1.5 1.8 1.1 0.0 1.3 2.0 1.5 0.4 0.7 1.1 1.7 0.6 0.9 2.7 0.9 0.5 1.2 1.6 2.1 0.9 1.8 0.6 1.1 0.8 1.2 1.8 0.7 0.5 0.9 1.0 0.5 0.4 0.9 1.5 0.6 0.2 3.2 1.2 31.3 1.5 2.6 0.9 0.5 1.0 0.9 0.8 1.7 5.1 7.8 1.4 6.4 2.7 2.5 1.4 6.5 3.0 5.1 5.2 1.6 3.3 2.3 3.3 1.9 1.6 3.9 2.2 0.4 2.7 8.8 1.5 0.9 3.7 1.7 1.2 4.7 5.6 2.2 0.6 4.6 0.5 7.7 2.7 4.6 4.2 3.1 2.2 1.9 8.9 4.5 1.1 0.7 2.8 19.8 16.3 5.5 4.5 2.3 3.6 4.8 9.0 0.7 2.2 0.2 2.3 3.3 6.6 8.9 14.1 5.5 2.8 3.1 8.3 8.7 4.3 6.3 10.7 8.7 1.7 6.2 1.4 0.5 1.2 0.1 0.4 0.7 1.6 0.2 0.4 0.4 7.0 1.2 1.1 0.5 0.5 1.0 1.0 1.0 1.5 1.8 0.9 2.7 2.1 0.9 1.8 0.2 1.5 1.7 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.0 75.5 0.0 0.1 0.2 0.0 2.7 0.0 0.2 0.2 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 144.9 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 26.5 0.4 0.0 0.3 0.1 0.4 0.1 0.0 0.1 CMTM2 "CKLFSF2, FLJ25732, MGC39436" ENSG00000140932 "CKLF like MARVEL transmembrane domain containing 2" Q8TAZ6 16 66579448-66588275 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 429 "testis: 648.9" "Group enriched" "Detected in some" 73 "Early spermatids: 3619.3;Late spermatids: 3073.4;Spermatocytes: 1347.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enriched" "Detected in some" 20 "REH: 32.1" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 36: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.81e-1)" "unprognostic (3.75e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (8.71e-2)" "unprognostic (3.31e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-2)" "unprognostic (3.27e-2)" "unprognostic (1.02e-4)" "unprognostic (1.80e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" 0.2 0.1 0.5 0.4 0.2 1.1 0.5 0.6 0.9 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.5 0.0 0.4 0.3 0.5 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.2 0.0 0.7 0.0 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.0 1.5 0.2 648.9 0.0 1.1 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.5 0.1 0.1 1.5 0.5 0.1 0.0 0.0 32.1 0.2 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.7 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.6 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 21.9 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 5.0 0.0 0.0 0.1 1.5 0.2 0.0 0.3 3619.3 0.1 0.1 2.3 0.0 0.0 1.1 0.2 0.2 1.8 0.0 0.1 18.9 0.1 1.1 0.3 1.4 0.0 0.6 0.0 0.0 0.9 0.3 3073.4 36.4 5.5 0.0 0.0 7.7 0.0 1.0 0.0 0.6 0.8 0.0 30.5 0.0 0.0 0.0 0.4 0.7 0.6 19.7 0.7 0.1 1347.5 20.4 0.0 0.0 0.1 1.7 0.4 0.0 0.0 CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 222.1;Granulosa cells: 140.8;Hofbauer cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" 49.3 16.6 15.5 25.0 14.3 20.0 32.8 15.6 28.1 40.2 9.5 16.8 7.1 30.4 16.6 10.4 25.5 32.7 26.2 15.6 18.0 19.7 10.7 35.4 32.3 24.9 15.8 38.9 7.9 29.4 10.1 44.4 19.3 23.4 12.1 3.0 17.4 16.7 6.4 22.2 18.8 27.7 17.0 36.1 11.9 59.7 19.1 35.5 16.1 13.0 20.9 34.3 26.7 20.4 6.7 33.8 93.4 66.2 68.4 42.6 59.2 17.5 78.6 34.4 34.0 18.6 21.0 0.2 47.7 49.0 59.7 7.8 63.7 57.4 27.3 34.6 23.2 21.5 4.4 53.5 92.2 65.8 77.4 85.5 4.5 36.6 7.7 141.3 78.9 59.5 34.6 0.7 42.8 7.8 53.1 108.9 45.0 0.5 31.8 164.7 65.6 3.3 16.4 0.8 9.9 33.9 8.5 0.3 58.5 59.9 0.7 59.3 54.0 48.7 58.8 12.0 21.1 4.4 0.7 21.8 30.5 50.0 53.7 7.9 14.2 9.9 9.2 13.9 12.9 2.6 10.3 10.5 12.3 0.9 8.0 9.8 8.0 8.6 8.9 24.9 15.7 5.8 15.5 14.3 15.6 28.1 15.6 18.0 24.9 15.8 19.3 17.0 19.1 20.4 38.0 0.0 7.1 0.3 12.9 14.7 33.5 10.0 6.8 0.5 12.3 25.7 2.0 4.3 6.4 5.5 0.0 10.7 101.2 0.4 0.0 28.1 2.8 4.9 56.0 50.4 12.5 12.8 0.6 6.4 222.1 62.6 2.6 6.2 91.3 140.8 44.3 1.3 119.8 0.0 0.3 0.7 8.2 74.7 77.9 9.4 39.4 78.0 28.4 10.3 61.5 10.0 82.4 8.0 0.2 41.0 0.1 24.5 5.7 40.8 0.1 4.4 3.1 0.8 6.6 26.3 36.1 4.9 8.1 1.1 8.7 9.4 68.9 10.5 0.2 21.6 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;choroid plexus: 49.5" "Cell type enhanced" "Detected in some" "Macrophages: 93.7;Muller glia cells: 32.0;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 106.2" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cell line enriched" "Detected in some" 7 "HEL: 91.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" 1.1 1.0 75.6 0.5 119.1 8.2 0.9 123.8 101.7 2.8 49.5 5.8 0.5 0.8 1.1 1.2 1.2 2.1 22.7 73.9 85.2 0.5 0.3 1.5 0.2 150.9 106.2 0.8 0.2 0.1 0.6 0.7 135.2 2.1 0.8 2.3 2.2 3.2 3.1 0.7 1.7 0.8 113.4 2.8 1.4 0.1 110.2 0.1 0.5 0.9 0.0 1.2 2.6 182.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.2 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.2 20.8 0.7 0.9 0.1 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.4 30.0 75.6 119.1 123.8 101.7 73.9 85.2 150.9 106.2 135.2 113.4 110.2 182.4 0.5 0.0 0.0 6.5 0.4 1.0 0.1 0.0 1.2 0.2 1.3 5.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.4 0.0 0.0 93.7 5.4 0.0 1.5 32.0 0.0 20.6 106.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 3.4 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 CMTM8 CKLFSF8 ENSG00000170293 "CKLF like MARVEL transmembrane domain containing 8" Q8IZV2 3 32238679-32370321 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 47.7" "Cell type enhanced" "Detected in many" "Adipocytes: 94.7;Cytotrophoblasts: 107.6;Granulosa cells: 129.9;Syncytiotrophoblasts: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "BEWO: 208.4;SK-BR-3: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055077, HPA073258" Approved Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA055077: AB_2682691, HPA073258: AB_2686591" "unprognostic (9.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-1)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (9.46e-2)" "unprognostic (5.67e-2)" "unprognostic (8.85e-2)" "unprognostic (1.29e-1)" "unprognostic (7.59e-2)" "unprognostic (2.56e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" 14.8 12.9 6.0 3.3 5.8 1.2 15.5 4.9 6.7 5.9 5.9 7.0 7.3 4.4 17.4 3.5 8.4 3.4 13.6 5.5 5.0 10.2 41.2 17.9 3.9 6.2 5.4 1.4 47.7 12.0 3.6 17.4 6.3 11.7 7.4 1.1 19.7 6.0 4.7 9.2 6.2 2.5 5.5 1.3 14.9 1.0 7.0 9.5 13.6 5.1 4.1 4.8 3.7 4.9 10.6 10.8 2.1 13.5 9.5 14.7 208.4 0.1 0.3 1.1 1.2 15.0 14.9 0.0 21.8 0.0 0.0 5.8 17.2 3.5 0.9 0.0 31.5 6.8 2.1 25.2 0.6 2.8 5.3 28.8 10.8 1.5 10.4 5.2 8.4 11.2 0.1 0.0 10.7 7.8 8.9 1.0 4.4 16.4 9.9 12.4 2.5 2.1 13.1 12.1 3.7 3.0 1.7 59.3 5.8 2.5 17.0 1.4 7.6 0.0 15.5 0.0 3.2 0.5 0.4 0.1 0.0 4.8 3.7 0.0 0.0 1.6 0.1 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.1 6.0 5.8 4.9 6.7 5.5 5.0 6.2 5.4 6.3 5.5 7.0 4.9 94.7 38.5 36.3 1.0 2.8 11.6 35.2 4.6 18.8 0.1 75.4 45.6 2.2 17.2 16.1 0.0 0.0 107.6 2.3 13.7 11.7 18.1 13.0 22.1 5.6 51.9 22.2 5.7 2.2 37.0 67.5 17.7 32.1 29.2 0.0 129.9 54.7 79.5 9.8 0.0 41.6 40.7 16.2 5.3 15.0 2.4 2.5 3.6 5.4 36.5 1.2 35.6 0.0 17.6 1.0 25.8 17.7 1.2 1.4 64.9 21.3 24.3 9.9 2.7 0.0 2.2 12.3 3.5 3.7 12.1 6.5 116.2 18.6 10.9 21.0 49.7 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear speckles" "HPA041700: AB_2677623, HPA048265: AB_2680334" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favorable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 6.7 8.8 4.0 10.3 4.6 7.2 15.9 4.6 4.2 7.6 8.0 10.1 14.9 8.5 12.2 14.3 9.0 9.4 7.0 3.2 4.7 12.5 14.3 11.4 14.4 5.1 4.4 11.2 8.1 10.7 7.8 10.6 4.8 10.8 10.4 7.3 13.3 8.0 5.7 10.3 14.2 9.0 5.2 13.6 10.0 13.8 4.9 10.7 14.1 5.7 17.9 9.7 7.6 6.6 17.8 11.6 23.2 19.5 18.9 15.3 10.6 14.9 18.2 17.4 18.4 10.6 26.5 10.0 18.4 13.7 18.9 19.4 11.1 14.2 24.9 10.5 7.9 22.3 13.1 8.3 20.3 16.8 37.7 12.7 24.7 15.4 17.9 12.8 18.5 22.2 11.6 6.6 31.1 15.9 18.8 23.1 11.0 14.2 6.7 28.5 10.2 24.5 16.3 19.5 12.0 12.8 15.1 12.2 15.4 10.3 18.0 10.4 18.7 21.1 15.1 15.5 11.4 13.3 17.6 21.3 14.7 14.6 16.8 22.6 9.6 9.2 10.8 10.3 13.2 13.1 10.6 11.7 13.7 12.0 11.4 11.1 0.7 16.6 6.9 3.9 9.8 11.4 4.0 4.6 4.6 4.2 3.2 4.7 5.1 4.4 4.8 5.2 4.9 6.6 11.4 3.2 11.8 13.7 28.1 14.1 14.5 10.7 15.9 20.3 23.9 13.7 8.6 20.0 9.4 16.5 31.3 24.2 30.2 25.8 7.9 12.2 95.6 12.6 15.1 14.6 18.6 17.0 9.9 9.7 12.7 11.5 15.8 11.5 8.2 26.1 18.9 32.7 16.1 15.2 10.3 20.5 18.3 18.0 11.4 30.9 16.8 13.6 1.8 21.5 17.8 12.1 51.5 17.6 21.5 12.9 15.2 12.4 17.9 13.5 46.3 17.7 6.5 25.5 6.6 11.1 10.1 26.1 13.8 22.0 24.3 26.4 20.0 21.8 17.9 18.2 CNEP1R1 "C16orf69, FLJ38101, NEP1-R1, TMEM188" ENSG00000205423 "CTD nuclear envelope phosphatase 1 regulatory subunit 1" Q8N9A8 16 50024410-50037088 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042815, HPA077906" Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA042815: AB_10794765, HPA077906: AB_2686868" "unprognostic (4.11e-2)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.43e-3)" "unprognostic (1.80e-1)" "unprognostic (3.42e-2)" "unprognostic (8.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (3.37e-3)" "unprognostic (5.09e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" 9.6 8.4 6.4 14.4 7.3 23.8 7.9 8.0 7.1 8.4 5.9 9.4 8.9 9.2 12.9 12.0 7.6 10.7 9.0 6.7 6.6 7.1 10.6 9.5 14.3 6.6 5.9 9.8 7.1 8.6 8.4 15.6 6.6 8.3 13.4 9.6 8.3 8.2 10.1 11.6 9.2 11.0 6.7 13.4 9.8 18.0 6.7 9.5 5.4 7.3 15.3 10.0 9.0 7.9 11.2 10.2 12.4 13.9 23.5 23.1 17.4 22.5 17.1 21.4 12.5 11.0 15.3 12.4 16.3 18.7 14.6 17.0 10.0 10.9 27.1 9.1 11.7 6.1 6.7 17.8 16.7 8.1 18.1 17.0 18.2 13.9 10.8 16.6 14.8 15.5 7.6 6.9 27.4 3.4 16.0 21.0 9.0 4.9 13.8 19.3 16.4 12.8 15.9 7.4 9.3 11.1 21.3 8.5 9.0 10.7 7.4 10.0 19.3 20.7 15.9 19.7 8.0 11.4 11.3 14.5 12.0 8.1 17.4 16.6 21.0 16.3 16.0 29.2 15.1 9.4 12.4 11.9 17.5 8.7 12.4 14.5 51.0 12.7 36.4 6.9 13.4 14.5 6.4 7.3 8.0 7.1 6.7 6.6 6.6 5.9 6.6 6.7 6.7 7.9 8.2 3.2 7.8 8.8 10.1 10.6 3.4 6.5 5.7 5.8 5.9 3.9 11.4 8.6 6.9 7.3 4.2 17.7 10.6 7.7 3.9 5.2 4.6 5.9 8.6 8.6 4.8 7.8 13.7 5.4 25.1 9.7 8.6 6.8 12.7 5.6 10.0 6.9 14.8 6.7 13.2 3.7 2.0 20.0 20.8 3.9 5.9 18.2 16.0 6.5 15.4 12.2 12.3 8.5 12.5 5.8 6.4 7.9 7.7 4.2 5.0 5.5 4.5 10.0 6.6 9.4 8.4 26.4 18.8 5.5 9.8 14.4 13.3 5.7 5.6 3.8 CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA002544: AB_2081856" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (7.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.50e-1)" "unprognostic (8.93e-3)" "unprognostic (1.47e-1)" "unprognostic (2.71e-3)" "unprognostic (4.78e-2)" "unprognostic (4.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (8.95e-4)" 73.2 61.7 40.2 50.9 42.1 37.2 73.6 45.2 49.5 59.8 58.5 86.9 99.4 49.6 50.8 72.5 67.0 74.4 84.6 42.8 47.2 79.9 232.9 46.7 61.2 44.3 43.4 44.0 41.8 59.8 41.2 58.4 44.8 57.2 95.1 60.3 49.7 57.1 58.9 36.0 85.4 68.2 49.1 33.8 45.4 37.1 41.3 56.2 65.0 95.5 79.0 95.1 39.4 50.7 233.4 141.3 113.8 129.2 301.0 380.9 107.8 276.8 348.6 232.0 264.4 86.5 316.4 289.7 180.2 209.2 141.6 226.5 208.3 200.3 287.5 111.9 124.5 112.1 80.9 152.8 303.6 136.5 90.2 314.4 244.3 217.1 304.0 236.8 221.3 117.7 111.5 95.5 262.4 138.4 151.5 102.9 84.2 266.3 281.3 114.8 191.8 97.3 264.2 171.4 95.5 106.3 163.4 127.8 316.7 104.8 197.5 144.9 143.7 194.7 192.9 165.4 167.8 59.7 138.8 141.2 235.9 115.3 176.5 5.3 84.6 10.7 32.5 66.8 54.8 64.3 57.3 47.0 86.0 55.2 75.1 52.1 20.9 44.0 53.7 48.4 65.1 96.6 40.2 42.1 45.2 49.5 42.8 47.2 44.3 43.4 44.8 49.1 41.3 50.7 41.1 35.3 60.6 14.7 64.9 105.7 86.2 186.1 141.7 41.9 69.2 64.0 85.6 50.1 79.8 46.0 20.9 95.7 48.1 98.8 90.1 89.3 44.4 54.8 57.9 72.3 104.4 65.0 26.9 62.3 123.4 90.3 52.5 32.8 197.3 32.4 70.3 140.0 115.5 67.3 34.8 91.5 99.7 102.8 80.0 17.0 60.0 73.5 83.6 9.4 110.3 59.9 35.0 17.6 22.5 65.6 96.6 65.8 84.0 92.0 149.9 164.7 79.9 45.1 46.0 60.5 68.1 68.7 64.1 144.9 110.0 70.9 69.3 68.4 123.0 91.4 CNIH4 HSPC163 ENSG00000143771 "Cornichon family AMPA receptor auxiliary protein 4" Q9P003 1 224356858-224379459 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 320.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044268 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "HPA044268: AB_10965330" "unprognostic (2.01e-1)" "unprognostic (1.34e-3)" "unprognostic (1.56e-1)" "unprognostic (1.66e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (4.47e-3)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (5.96e-3)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.27e-6)" "unprognostic (3.15e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-3)" "unprognostic (1.63e-2)" 21.9 19.4 14.6 12.1 15.3 26.9 19.7 15.1 17.4 15.5 17.8 19.9 16.6 18.4 12.1 23.5 16.0 12.1 18.3 14.7 16.0 19.4 18.3 21.4 9.3 15.5 15.1 15.6 11.8 18.9 10.5 18.5 15.9 13.2 15.5 14.8 14.4 15.6 25.1 19.5 17.8 19.2 14.9 15.1 16.5 10.0 14.8 9.7 12.3 19.1 11.3 20.8 18.3 15.2 81.1 110.4 51.6 46.3 91.6 59.5 42.5 54.4 50.7 55.8 51.1 110.7 93.7 24.0 86.5 54.9 60.5 94.6 95.4 59.9 58.6 29.8 101.1 20.6 70.7 59.0 79.6 40.9 38.9 61.7 80.8 69.7 91.0 55.9 74.8 42.3 49.3 31.1 66.8 62.8 17.6 37.0 68.2 106.3 63.0 19.1 94.8 26.4 92.4 89.9 13.1 43.9 82.4 90.1 69.3 64.6 69.4 96.2 71.9 51.5 44.6 64.2 112.6 13.4 18.7 23.9 63.5 55.3 56.1 54.5 60.0 72.7 36.7 106.6 35.4 25.8 47.8 42.2 52.3 23.9 38.1 41.8 48.4 31.6 153.7 17.5 36.0 58.1 14.6 15.3 15.1 17.4 14.7 16.0 15.5 15.1 15.9 14.9 14.8 15.2 68.4 125.0 84.9 9.8 27.3 66.5 137.0 320.0 42.7 20.4 49.5 74.0 117.8 61.5 160.2 53.3 29.2 145.9 29.7 138.7 29.4 140.3 16.2 61.3 62.6 76.2 15.6 56.2 15.4 125.2 180.6 90.9 27.5 60.8 32.3 54.0 58.5 70.1 107.6 20.2 14.2 38.5 120.1 124.4 60.0 10.9 65.9 86.5 58.7 12.2 72.9 52.9 45.3 13.6 16.9 132.9 116.7 65.1 28.1 148.7 136.2 101.5 127.7 34.3 85.5 45.5 196.5 145.6 63.4 73.0 86.9 161.2 50.4 45.7 72.7 149.0 COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 414.8;Proximal tubular cells: 464.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" 17.5 44.2 28.1 23.3 30.9 20.1 22.1 37.4 49.2 13.9 23.6 23.9 24.3 24.8 29.9 21.5 17.2 15.3 42.9 27.9 30.1 50.2 29.6 15.8 21.4 30.3 30.3 35.4 23.2 22.8 11.1 17.7 28.8 28.7 18.7 58.3 17.1 18.6 43.3 15.2 25.0 20.5 29.2 15.0 23.1 25.0 29.3 16.3 37.0 37.4 16.5 20.4 9.6 30.1 132.6 34.1 33.5 100.4 22.5 17.3 75.2 54.0 35.7 31.0 27.2 93.9 88.9 21.3 65.7 36.6 58.3 36.1 17.8 43.0 40.8 56.0 15.6 38.6 47.6 85.7 28.7 95.7 57.5 16.0 20.2 44.5 30.8 44.9 35.2 22.7 81.2 80.2 63.0 33.0 53.5 43.5 84.2 94.9 68.6 38.5 42.0 121.5 59.5 33.1 19.6 54.2 68.1 36.1 79.6 32.1 67.0 28.7 69.3 67.3 88.7 59.9 120.1 128.0 188.7 43.7 90.9 108.2 65.3 14.5 15.3 21.4 27.1 36.4 26.3 34.2 31.3 30.2 26.5 32.6 21.2 28.7 3.9 24.2 34.5 26.1 43.4 20.4 28.1 30.9 37.4 49.2 27.9 30.1 30.3 30.3 28.8 29.2 29.3 30.1 66.7 19.2 52.1 44.1 77.7 85.1 115.1 144.3 38.1 111.5 104.4 110.1 68.6 183.0 90.5 191.3 45.9 231.5 74.4 97.7 414.8 154.1 38.6 78.4 74.1 61.4 61.8 82.0 16.6 188.9 164.6 56.1 57.6 119.5 73.4 53.1 42.5 294.8 122.1 89.2 24.4 91.7 77.3 64.8 79.6 75.9 69.6 73.4 72.9 9.4 97.6 195.2 110.2 27.6 34.1 178.6 87.0 80.1 51.9 75.9 134.8 464.0 67.7 133.4 65.7 83.2 85.0 67.1 122.4 61.6 75.6 264.5 81.4 63.6 115.3 87.8 COX7A2 "COX7AL, COXVIIa-L" ENSG00000112695 "Cytochrome c oxidase subunit 7A2" 6 75237675-75250323 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 4705.1;Late spermatids: 3873.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (8.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.98e-2)" "unprognostic (2.15e-2)" "unprognostic (1.34e-1)" "unprognostic (5.67e-3)" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" "unprognostic (7.70e-2)" "unprognostic (2.73e-3)" "unprognostic (7.44e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" 180.5 204.2 346.7 94.5 356.4 171.8 166.2 374.6 579.3 133.0 382.9 314.4 196.3 128.4 215.0 253.0 135.7 105.5 601.8 357.5 401.2 374.6 307.6 146.1 117.3 344.1 349.7 103.8 154.1 407.8 232.6 92.4 355.2 163.4 327.9 332.2 160.4 124.0 185.3 163.6 200.9 158.5 358.6 138.6 286.4 497.7 353.5 166.6 146.8 293.8 156.6 160.5 154.1 378.4 116.5 260.5 334.6 276.7 195.9 220.0 242.3 276.9 252.7 270.3 291.3 471.1 172.9 188.1 239.0 251.9 363.1 247.1 236.1 299.9 336.8 347.8 482.6 283.6 842.1 630.6 200.8 305.6 319.9 240.7 392.7 250.9 163.2 283.4 318.7 420.8 255.2 266.0 370.4 536.6 130.7 329.7 210.9 569.4 472.5 210.2 169.0 500.7 436.3 745.0 228.2 275.3 172.4 312.0 301.7 273.2 190.9 843.6 156.4 118.8 218.2 95.9 319.5 373.2 444.7 221.4 135.7 342.5 237.3 693.0 582.0 585.0 435.6 663.4 468.5 659.6 563.3 527.9 619.7 559.7 551.1 511.9 437.7 496.6 696.0 781.4 680.8 1055.8 346.7 356.4 374.6 579.3 357.5 401.2 344.1 349.7 355.2 358.6 353.5 378.4 370.9 304.5 371.3 15.0 391.8 553.7 624.1 2000.6 268.6 251.0 584.8 693.0 2518.6 630.5 1019.4 503.9 120.9 686.3 348.5 1504.8 2602.2 800.4 4705.1 460.2 288.0 382.5 663.0 354.3 18.9 1007.3 787.6 367.5 414.9 451.7 300.1 269.4 385.8 1485.8 870.3 154.8 22.4 1283.5 1468.9 484.8 499.6 3873.2 355.7 420.2 846.6 10.3 715.3 390.3 396.5 14.1 20.9 1157.5 1498.6 339.3 593.7 848.5 1790.7 2008.3 772.8 359.9 407.6 303.7 587.8 2905.4 230.0 627.9 626.4 818.3 381.9 336.4 1242.8 994.8 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.0;Hepatocytes: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria NA NA 45000 "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008835: AB_1078563" "prognostic unfavorable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favorable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 24.3 27.7 16.0 22.3 18.4 38.9 22.7 20.2 17.3 20.4 32.0 67.4 70.7 25.1 7.3 22.0 25.4 27.7 25.4 14.7 17.7 38.4 67.9 25.3 15.9 20.6 22.0 18.3 23.6 27.6 14.3 18.4 19.3 20.3 44.6 22.6 26.0 21.9 9.9 17.0 71.3 34.9 15.9 27.4 35.6 13.5 22.1 14.0 15.4 14.3 12.3 18.7 18.0 13.9 29.4 50.9 7.3 48.6 31.2 28.0 2.1 22.9 18.8 17.7 3.6 2.0 96.0 0.1 82.2 60.4 62.2 93.5 63.9 13.6 5.3 46.8 6.3 71.5 52.3 24.0 46.4 41.9 82.6 29.2 6.6 35.5 21.4 24.1 63.5 28.2 7.6 56.8 16.5 83.6 34.4 73.7 0.8 149.7 53.2 94.7 1.2 127.1 41.7 71.7 1.0 31.8 63.0 119.9 20.2 4.8 107.4 40.0 64.5 38.3 0.9 77.7 33.5 43.9 60.1 29.2 40.3 30.3 42.8 8.2 6.6 9.5 7.3 7.7 4.2 1.9 4.4 4.4 4.4 2.0 2.7 5.5 3.2 4.9 6.7 10.4 2.8 2.7 16.0 18.4 20.2 17.3 14.7 17.7 20.6 22.0 19.3 15.9 22.1 13.9 44.4 38.5 28.8 35.6 13.5 9.4 11.0 9.0 28.5 4.8 9.6 7.6 25.5 22.8 18.0 23.9 64.6 15.9 39.3 110.0 19.6 13.8 14.7 33.2 22.6 30.4 16.2 30.9 5.6 9.5 3.9 16.6 31.1 56.7 29.7 23.0 40.7 108.3 15.7 1.7 5.7 48.9 10.2 39.1 11.5 43.9 9.6 24.6 0.0 28.1 31.4 12.7 23.7 7.1 1.7 8.5 43.4 32.0 28.6 9.6 83.4 11.8 23.8 43.0 39.5 18.3 21.1 14.5 10.0 14.8 7.7 7.8 24.0 17.3 67.4 9.2 CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 242.7;skeletal muscle: 144.5;testis: 80.7;tongue: 228.0" "Group enriched" "Detected in many" 4 "Early spermatids: 45.4;Late spermatids: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA079265 Enhanced NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA079265: " "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (6.71e-3)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (8.89e-2)" "unprognostic (7.16e-2)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-3)" "unprognostic (9.76e-3)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" "unprognostic (1.14e-1)" "unprognostic (8.43e-2)" "unprognostic (3.15e-5)" 10.3 9.3 13.8 11.4 15.5 13.4 15.7 17.4 17.4 7.7 12.2 14.0 13.5 4.6 10.3 16.6 7.3 6.1 242.7 13.6 14.7 25.1 25.6 10.5 14.4 16.7 14.6 5.0 18.3 34.1 23.5 8.1 15.8 15.7 10.6 17.1 13.1 3.4 144.5 14.1 22.2 3.6 13.6 27.5 13.0 80.7 16.1 9.8 26.7 228.0 13.1 9.9 10.3 17.8 8.2 7.7 24.5 9.0 5.3 3.1 17.5 0.3 3.1 4.1 4.5 3.6 7.2 16.3 2.2 2.0 6.0 13.6 12.9 2.9 3.6 6.5 14.2 8.0 26.2 3.9 1.4 8.5 22.3 1.8 22.0 2.9 4.8 15.0 0.7 11.4 2.9 27.8 3.9 11.9 2.9 16.3 5.2 4.3 4.9 15.2 7.8 3.5 10.3 19.6 6.6 12.7 5.7 9.7 10.9 14.8 10.8 17.9 1.6 11.4 11.4 7.4 2.8 22.3 5.5 8.7 4.9 15.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.8 15.5 17.4 17.4 13.6 14.7 16.7 14.6 15.8 13.6 16.1 17.8 0.5 0.0 11.0 0.0 0.8 0.3 0.0 1.0 1.8 1.9 2.2 1.0 3.7 1.5 1.5 3.7 2.1 0.5 0.2 5.6 0.0 2.2 45.4 0.9 0.1 1.0 0.0 0.0 0.0 2.1 0.6 1.4 5.6 0.4 7.0 0.1 0.4 2.1 0.6 3.3 0.0 5.2 0.0 0.6 0.8 109.3 0.3 1.0 1.8 0.0 6.3 0.4 0.0 0.0 0.0 1.0 6.4 0.7 0.4 0.0 3.5 0.5 3.7 2.0 0.0 0.9 0.3 16.3 2.4 1.0 0.3 0.4 1.2 0.0 4.2 0.1 CPT1C "CATL1, CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;pituitary gland: 28.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.4;Excitatory neurons: 34.0;Horizontal cells: 32.0;Inhibitory neurons: 28.1;Late spermatids: 29.7;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in many" 5 "glioma: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.2;AN3-CA: 33.2;SCLC-21H: 27.4;SH-SY5Y: 70.1;U-87 MG: 29.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014529, HPA063621" Approved Approved Centrosome NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Centrosome "HPA014529: AB_1847206, HPA063621: AB_2732706" "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.84e-4)" "unprognostic (4.36e-1)" "unprognostic (1.92e-10)" "unprognostic (9.44e-4)" "unprognostic (3.35e-2)" "unprognostic (3.91e-1)" "unprognostic (4.72e-3)" 3.4 5.3 14.0 1.6 14.8 0.0 2.1 8.5 19.1 6.5 18.8 2.6 1.3 8.1 2.3 1.0 4.9 4.4 3.8 19.2 15.6 1.7 0.8 2.1 1.3 10.1 9.2 5.1 1.4 1.4 28.4 0.7 10.3 3.4 0.6 12.4 1.0 2.5 0.7 1.0 1.8 4.6 4.9 4.9 1.5 3.5 12.9 0.2 2.4 0.2 0.6 2.7 3.7 14.4 0.0 0.0 40.2 33.2 14.0 11.0 0.0 12.6 25.2 16.2 22.4 0.7 0.0 0.8 0.0 12.7 2.0 3.0 0.0 0.0 8.5 0.6 0.1 0.0 0.1 0.0 22.7 0.0 0.0 12.7 0.0 13.3 0.1 4.3 22.2 0.1 0.1 0.0 0.9 0.7 0.2 0.0 1.8 2.7 8.8 0.0 0.0 0.0 0.9 0.0 27.4 70.1 0.1 0.1 0.0 0.6 0.1 0.1 18.3 1.0 0.2 7.7 6.7 0.2 3.2 0.4 29.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 14.8 8.5 19.1 19.2 15.6 10.1 9.2 10.3 4.9 12.9 14.4 3.8 0.0 0.0 7.5 0.4 2.2 3.1 0.5 3.4 43.4 0.9 1.3 1.4 1.5 0.0 0.0 16.7 1.1 0.3 0.1 0.0 0.0 8.9 0.5 14.1 7.4 0.0 0.0 34.0 0.0 4.4 6.0 0.0 1.2 0.0 1.9 5.0 0.1 0.3 32.0 28.1 0.1 0.0 0.9 1.2 29.7 3.4 0.8 0.0 7.5 0.0 18.3 0.0 21.1 14.9 0.3 0.0 13.2 1.4 2.1 0.0 0.0 0.0 19.1 0.0 5.8 6.3 3.1 7.0 1.0 1.8 1.1 0.7 4.4 0.2 1.6 CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933816-9945406 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.3;hTERT-RPE1: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" 32.7 37.3 63.6 11.4 63.5 9.3 24.8 69.1 94.4 27.7 59.1 57.5 14.0 31.3 17.0 18.0 34.9 16.5 73.2 63.9 65.7 43.0 57.1 27.5 12.4 64.7 63.0 32.5 27.6 22.7 70.9 17.9 66.3 47.6 12.1 16.4 26.3 34.5 48.9 20.1 25.9 22.2 58.6 28.6 35.6 23.6 65.5 10.5 67.6 26.4 9.2 33.6 24.4 68.2 6.4 8.1 19.3 8.8 30.1 17.6 110.3 26.7 8.0 6.1 11.7 11.1 20.7 8.4 57.6 17.7 27.7 4.5 10.4 17.6 4.9 15.2 9.2 7.3 15.2 28.2 68.7 3.3 29.3 21.7 32.3 15.2 13.6 77.2 28.8 11.1 9.5 10.4 6.1 15.5 3.6 19.3 5.7 30.1 6.6 4.8 3.1 21.6 25.9 9.9 6.9 26.7 12.6 10.3 24.3 27.5 27.9 17.0 21.7 12.1 19.5 16.2 6.3 10.7 14.2 15.2 27.3 7.8 13.0 12.3 10.2 9.3 11.9 9.8 12.2 7.9 8.9 11.5 6.9 8.7 11.3 10.4 1.8 13.8 12.9 12.3 7.2 9.5 63.6 63.5 69.1 94.4 63.9 65.7 64.7 63.0 66.3 58.6 65.5 68.2 24.7 19.2 17.5 43.4 14.1 9.7 26.2 48.5 15.9 21.5 17.5 15.0 41.9 31.5 24.0 16.5 16.7 23.7 15.1 10.9 7.9 19.6 6.8 10.3 7.0 20.2 27.0 7.8 38.0 4.4 11.5 20.1 19.4 12.9 21.0 18.8 19.2 14.9 20.6 32.0 37.1 19.1 38.7 8.8 9.0 10.1 32.0 10.0 12.4 15.0 13.9 18.3 27.8 14.6 21.7 8.7 20.4 26.4 15.3 31.4 18.8 11.1 13.2 15.8 26.3 11.0 17.1 68.0 26.5 9.6 12.4 22.2 15.4 11.2 15.4 20.2 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 87.1 52.8 81.1 41.2 82.6 51.6 88.3 80.8 95.1 93.6 66.0 73.0 41.4 82.7 52.5 69.0 83.3 48.7 80.9 82.9 73.7 70.2 37.4 92.2 40.3 78.9 78.6 109.5 64.9 74.1 85.1 71.2 79.5 80.3 35.5 47.3 71.6 44.9 60.5 94.8 50.9 45.3 70.2 63.6 58.0 29.5 83.2 33.3 64.4 47.2 37.8 65.7 88.4 93.9 101.5 57.4 121.6 114.7 61.5 88.3 92.1 126.9 168.6 116.7 114.3 63.9 76.7 74.2 53.0 120.7 70.7 77.9 96.1 177.9 79.2 123.0 215.2 23.9 181.2 47.4 123.7 48.3 61.9 90.2 143.8 171.7 220.3 141.0 121.1 60.6 50.9 155.0 110.8 68.4 71.1 60.9 87.2 67.3 69.1 130.8 90.1 123.4 99.0 92.4 181.6 69.3 102.9 109.3 124.7 68.0 59.5 73.0 134.3 94.0 111.3 58.7 102.1 61.2 105.2 104.5 151.0 56.9 176.3 4.8 1.6 3.6 3.0 0.8 3.8 2.1 3.4 3.0 1.8 3.1 1.9 2.5 3.8 5.7 0.5 15.9 1.6 1.2 81.1 82.6 80.8 95.1 82.9 73.7 78.9 78.6 79.5 70.2 83.2 93.9 73.4 38.5 21.7 0.0 32.3 78.6 158.8 89.1 68.9 132.6 53.7 42.4 49.8 34.3 73.9 23.9 60.5 35.2 42.3 28.4 7.9 30.8 46.0 94.3 72.5 76.4 62.8 12.6 0.0 41.8 49.2 60.8 39.8 126.5 3.8 46.6 45.0 21.3 23.1 72.3 0.0 46.0 46.8 17.6 54.1 69.1 85.4 21.8 60.5 0.0 13.3 117.9 28.8 0.0 0.0 57.5 33.1 66.2 83.5 160.5 9.0 6.5 62.8 60.7 72.3 85.7 98.0 8.0 20.0 50.3 104.7 125.5 26.0 34.9 37.6 280.8 CTAGE1 "CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2" ENSG00000212710 "Cutaneous T cell lymphoma-associated antigen 1" "Q96RT6, Q9HC47" 18 22413599-22417915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "testis: 10.3" "Group enriched" "Detected in some" 4 "Early spermatids: 117.4;Spermatocytes: 36.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922, CAB016204" Uncertain NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "CAB016204: AB_673617, HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (1.41e-1)" "unprognostic (5.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.52e-1)" "unprognostic (1.70e-2)" "unprognostic (3.15e-1)" "unprognostic (1.63e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.1 0.0 0.1 0.0 0.0 0.5 0.4 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.3 16.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.5 36.1 0.8 0.0 0.3 0.1 0.1 0.1 0.0 0.6 CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.5;Late spermatids: 29.3;Theca cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 27.9;monocytes: 10.4" "Cell line enhanced" "Detected in all" "HDLM-2: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046947 Supported "Vesicles,Intermediate filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Intermediate filaments" "HPA046947: AB_2679872" "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 10.3 19.5 9.5 10.0 17.0 10.2 9.6 13.5 12.1 20.3 12.1 8.3 12.2 11.3 6.4 8.7 10.3 13.1 10.5 10.8 10.3 15.2 15.9 11.6 10.0 16.5 16.8 12.1 27.0 13.6 9.6 12.9 18.0 10.8 7.2 6.8 12.0 11.6 15.3 19.2 11.0 8.6 10.9 12.1 15.0 24.8 13.2 8.8 9.2 7.4 9.5 9.1 9.4 28.0 17.6 37.0 22.6 18.2 34.5 16.9 13.0 19.6 28.8 21.1 26.0 21.0 16.0 10.2 17.8 11.6 55.9 40.1 19.8 12.1 12.6 144.3 33.7 10.8 32.2 19.3 46.5 8.0 81.3 23.8 14.2 20.2 15.4 28.1 22.2 18.7 12.6 15.9 16.6 15.1 7.8 7.9 9.8 12.2 16.8 16.4 9.3 23.0 15.3 16.2 3.9 17.2 19.2 24.4 20.3 19.0 17.1 7.7 24.2 17.2 11.6 40.3 13.3 12.4 20.0 4.2 28.1 7.8 11.8 27.9 10.4 21.8 3.0 6.9 4.9 5.8 4.0 5.7 9.7 4.9 4.5 5.5 3.1 5.2 7.1 34.3 4.3 7.3 9.5 17.0 13.5 12.1 10.8 10.3 16.5 16.8 18.0 10.9 13.2 28.0 4.4 3.2 2.2 6.5 4.8 1.7 3.5 2.5 4.0 1.6 6.3 5.0 5.2 5.7 2.7 12.9 10.4 6.1 5.2 3.6 0.0 6.7 35.5 5.7 4.4 5.3 2.4 4.0 3.4 6.4 7.1 6.0 7.7 4.3 8.2 6.7 9.3 7.6 25.2 5.0 3.4 2.5 4.1 7.2 5.9 29.3 9.6 12.1 5.4 3.7 10.0 6.5 3.1 5.5 11.1 6.4 3.3 12.8 4.5 6.5 3.2 9.5 7.0 3.9 6.6 3.7 3.5 19.7 8.7 2.9 2.4 8.5 3.3 30.9 1.8 3.2 CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Group enriched" "Detected in some" 5 "Microglial cells: 177.1;NK-cells: 350.1" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 449.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 21 "RPMI-8226: 589.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" 2.3 3.8 6.2 6.9 6.4 1.1 5.1 8.6 6.0 2.7 1.7 1.1 1.2 2.7 4.2 0.8 6.1 2.6 2.4 7.7 8.4 2.5 2.0 9.9 2.1 17.3 14.8 1.6 0.7 4.5 1.0 4.6 18.9 3.5 1.1 0.5 7.6 7.2 6.5 2.3 0.9 3.5 21.5 11.9 1.4 1.8 17.4 2.0 2.4 2.2 5.3 2.4 0.3 26.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.2 6.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 24.5 0.0 0.2 0.2 0.5 0.1 0.0 0.0 0.2 0.1 589.8 0.0 0.0 0.1 0.1 0.0 8.1 0.0 0.2 0.1 16.5 0.0 0.0 0.1 0.1 0.0 0.5 1.0 0.1 0.0 28.6 0.0 7.7 99.6 1.8 264.0 261.2 3.4 0.8 55.9 145.2 94.4 0.7 19.0 122.4 20.8 39.7 449.2 7.1 1.5 232.7 6.2 6.4 8.6 6.0 7.7 8.4 17.3 14.8 18.9 21.5 17.4 26.4 0.8 0.0 0.5 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.8 3.8 0.4 0.0 0.6 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.2 0.2 0.1 3.5 0.0 2.1 0.3 0.0 0.0 0.3 0.0 0.0 5.1 0.1 0.7 0.3 4.1 0.0 0.6 0.0 0.0 15.0 28.0 0.3 0.3 43.2 0.0 177.1 50.3 0.1 350.1 2.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.7 0.2 6.6 0.4 1.3 0.7 0.2 0.0 0.6 0.0 22.6 0.1 0.1 0.0 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CYB561A3 CYBASC3 ENSG00000162144 "Cytochrome b561 family member A3" Q8NBI2 11 61348754-61362283 "Predicted membrane proteins" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 251.4" "Cell type enhanced" "Detected in all" "dendritic cells: 145.1;Melanocytes: 320.2;Theca cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "memory B-cell: 314.5;naive B-cell: 386.6;plasmacytoid DC: 841.4" "Group enriched" "Detected in all" 9 "B-cells: 386.6;dendritic cells: 841.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045674, HPA052548" Approved Approved Nucleoli,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles Nucleoli "HPA045674: , HPA052548: AB_2681866" "unprognostic (2.61e-1)" "unprognostic (8.78e-2)" "unprognostic (4.16e-1)" "unprognostic (3.62e-2)" "unprognostic (1.37e-1)" "unprognostic (9.41e-3)" "unprognostic (7.41e-3)" "unprognostic (2.48e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.83e-1)" "unprognostic (3.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-3)" 19.5 251.4 10.2 32.6 11.5 26.0 17.3 10.5 10.7 17.1 17.4 33.3 19.2 24.1 18.7 19.6 30.4 27.5 12.3 11.0 10.1 15.3 31.0 21.3 70.3 13.0 13.7 27.1 24.4 21.5 13.8 17.3 12.6 20.9 27.8 11.4 21.8 19.8 26.1 76.0 27.8 18.8 12.3 49.7 20.8 13.6 12.1 28.1 18.5 17.7 70.4 22.9 16.2 14.0 50.2 80.6 13.4 40.6 67.8 41.9 11.3 26.0 37.3 29.8 28.9 22.6 54.3 98.1 42.1 46.2 24.0 67.5 13.6 72.2 20.1 64.5 28.5 18.3 53.6 16.5 32.0 24.9 42.3 63.4 95.7 65.3 30.0 25.0 44.1 46.1 55.5 57.3 51.2 53.3 45.7 11.4 24.5 44.7 51.9 52.2 14.0 72.6 35.2 48.1 16.2 26.1 54.7 71.5 60.5 9.6 58.6 29.3 31.7 34.2 17.8 34.2 35.6 34.3 49.9 56.8 50.6 44.2 46.4 19.4 66.4 35.5 31.0 53.8 28.6 314.5 22.1 29.2 63.5 386.6 23.5 24.6 21.8 31.5 64.0 841.4 23.6 84.8 10.2 11.5 10.5 10.7 11.0 10.1 13.0 13.7 12.6 12.3 12.1 14.0 13.0 6.4 22.8 6.8 96.2 28.3 18.3 86.6 19.9 15.9 19.6 18.7 1.9 10.0 30.0 12.9 31.3 49.9 145.1 53.6 11.7 26.2 53.6 15.4 12.0 13.5 19.2 14.1 4.3 38.8 39.5 16.4 21.4 7.5 8.8 13.0 15.4 21.0 51.4 18.5 4.1 28.9 22.4 23.8 21.2 14.2 20.8 47.9 320.2 8.4 57.1 23.7 28.8 5.5 7.2 26.6 48.9 20.7 10.5 15.9 55.6 13.7 72.0 56.2 13.1 14.8 15.8 7.2 11.5 18.4 24.0 39.5 18.7 128.9 30.7 16.2 CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82442586-82450829 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 47.4;Ductal cells: 39.7;Granulosa cells: 56.1;Hofbauer cells: 80.2;monocytes: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cell Junctions" "HPA045696: AB_2679421" "unprognostic (1.87e-2)" "unprognostic (6.92e-3)" "unprognostic (2.25e-1)" "unprognostic (2.15e-3)" "unprognostic (5.75e-2)" "unprognostic (2.05e-3)" "unprognostic (3.81e-3)" "unprognostic (4.86e-2)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-3)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.83e-11)" "unprognostic (1.47e-1)" "unprognostic (5.51e-2)" "unprognostic (7.78e-2)" "unprognostic (9.14e-3)" 39.2 35.7 34.4 70.1 36.1 37.2 37.4 36.7 42.6 40.9 36.3 33.8 24.6 33.7 23.7 34.1 34.9 46.0 30.7 33.2 35.6 51.2 64.9 41.4 110.5 41.8 37.8 33.8 45.0 24.5 25.9 30.7 37.7 43.4 27.7 9.9 30.8 23.2 14.9 29.4 49.3 40.7 37.1 117.4 36.9 17.8 36.7 63.3 28.9 13.6 72.1 49.7 28.2 40.6 48.5 67.4 37.1 61.4 57.9 60.6 35.0 42.2 51.6 61.8 73.1 26.2 47.8 122.4 37.8 60.6 75.4 48.3 25.7 32.4 42.6 87.4 21.1 33.4 19.2 30.6 59.3 38.1 94.4 68.5 45.7 53.1 29.3 59.0 81.5 90.3 28.4 88.2 52.9 50.8 160.2 33.0 27.5 65.0 35.3 120.1 22.7 93.1 44.8 60.7 31.7 60.7 77.0 88.1 55.7 66.3 91.4 148.3 27.9 46.7 46.0 79.3 45.9 157.8 58.3 93.1 61.2 61.0 42.5 223.8 136.7 182.9 96.3 181.3 74.7 114.8 88.2 93.6 125.2 115.9 73.0 71.1 300.6 104.5 169.4 130.9 101.1 161.4 34.4 36.1 36.7 42.6 33.2 35.6 41.8 37.8 37.7 37.1 36.7 40.6 35.6 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 19.0 17.1 0.0 0.0 0.0 22.0 0.0 27.6 47.4 0.0 9.8 39.7 0.0 11.9 21.9 12.9 0.0 0.0 0.0 33.6 36.1 10.9 0.0 12.4 0.0 56.1 0.0 0.0 80.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 54.8 0.0 0.0 0.0 0.0 34.9 0.0 0.0 11.1 0.0 0.0 19.6 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 27.6 19.5 23.8 0.0 0.0 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 1125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" 84.7 173.2 92.1 62.4 97.2 104.4 72.7 115.4 103.8 71.4 102.4 162.6 171.2 75.9 35.7 155.5 67.8 39.5 527.7 92.3 105.3 152.6 180.4 56.7 55.8 99.8 96.9 63.6 101.2 163.3 58.2 45.8 103.1 67.8 111.0 42.0 104.4 70.0 730.0 106.5 127.5 59.9 94.9 70.1 139.6 38.9 106.9 63.4 64.8 724.9 61.0 92.0 86.5 99.6 172.0 381.4 98.9 208.4 80.5 88.5 189.6 96.7 116.7 240.2 156.9 269.4 208.2 241.0 210.8 129.8 116.2 247.3 217.9 191.2 89.8 148.2 289.2 259.7 306.5 250.4 143.1 154.7 162.5 129.4 234.9 153.2 301.4 80.6 141.3 163.7 240.4 208.2 127.7 616.8 292.0 143.5 115.1 476.8 1125.5 253.7 132.4 422.1 199.7 273.0 263.3 117.2 267.8 365.7 200.0 54.0 302.5 233.2 108.8 152.1 321.6 169.6 299.7 229.1 179.7 183.8 193.2 261.9 198.4 185.7 340.4 95.7 131.6 360.4 139.8 208.7 108.1 141.5 444.1 180.3 104.9 134.6 32.7 187.8 278.8 251.0 158.2 397.1 92.1 97.2 115.4 103.8 92.3 105.3 99.8 96.9 103.1 94.9 106.9 99.6 77.0 19.2 29.3 23.5 94.0 156.1 191.9 394.8 62.6 113.6 110.7 102.6 402.3 181.6 156.0 79.1 81.3 263.6 61.7 516.1 817.8 239.9 81.2 59.1 68.1 88.0 146.4 130.6 14.4 289.1 257.1 102.8 144.8 60.2 59.7 89.2 62.4 239.4 246.3 87.5 21.6 390.4 272.6 104.8 139.4 88.6 88.9 101.4 179.7 12.2 208.4 115.2 92.7 12.1 17.5 290.6 332.5 90.7 149.9 237.9 570.0 468.6 86.1 100.9 72.3 109.4 250.6 83.1 116.7 212.9 163.7 236.8 63.8 197.5 602.6 258.3 CYHR1 "CHRP, KIAA0496, MGC13010" ENSG00000187954 "Cysteine and histidine rich 1" Q6ZMK1 8 144449582-144465667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053653, HPA059543" Approved Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA053653: AB_2682219, HPA059543: AB_2684056" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.58e-2)" "unprognostic (8.28e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (4.02e-2)" "unprognostic (2.63e-1)" "unprognostic (2.13e-1)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (1.54e-2)" 33.6 57.9 61.2 9.2 60.3 11.1 37.1 58.2 76.1 50.5 57.1 46.8 15.8 41.0 22.8 34.7 43.1 16.0 58.9 61.7 59.5 43.1 48.8 26.6 15.3 63.7 59.9 44.7 60.9 28.9 67.5 10.2 58.6 70.5 8.8 11.2 40.5 27.6 45.9 41.5 30.0 12.0 60.5 35.0 42.1 69.8 59.6 13.7 44.1 22.6 8.5 48.9 40.3 61.2 23.0 27.6 18.3 22.6 30.8 20.7 22.9 15.5 15.9 14.6 18.4 12.8 30.6 10.4 32.5 23.3 18.1 34.0 14.4 22.6 5.6 25.3 23.9 23.6 33.7 22.1 42.9 6.0 12.4 35.6 29.9 18.2 22.7 32.2 16.9 29.0 34.8 27.7 14.0 51.5 28.9 16.6 12.0 34.5 57.5 27.3 7.7 29.6 22.5 19.5 26.7 16.4 33.5 27.9 36.6 13.9 37.5 23.8 20.1 18.4 21.5 20.5 15.6 14.0 9.9 8.4 26.5 20.2 15.2 2.9 11.7 7.0 9.5 8.4 15.5 12.9 11.9 7.8 12.7 14.0 22.2 12.5 5.8 5.3 9.5 27.0 5.0 9.6 61.2 60.3 58.2 76.1 61.7 59.5 63.7 59.9 58.6 60.5 59.6 61.2 32.6 35.3 26.5 52.5 18.5 30.5 46.2 31.8 43.9 75.6 68.7 69.6 19.0 45.8 28.7 58.8 25.0 29.2 33.3 43.2 43.0 28.1 12.5 37.2 37.3 28.9 33.7 23.4 45.9 28.7 20.1 36.4 32.6 32.7 5.1 42.9 37.9 45.6 25.6 90.9 39.4 44.0 36.7 26.7 23.2 44.1 50.7 23.0 26.6 18.7 31.0 120.5 22.6 31.7 37.2 23.2 42.9 39.9 26.2 48.5 47.6 35.0 41.7 59.0 39.5 37.4 35.5 45.8 32.3 36.8 38.8 16.7 24.3 82.2 47.3 35.6 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 313 "liver: 513.4" "Cell type enriched" "Detected in some" 57 "Hepatocytes: 85.7" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-BR-3: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" 0.2 0.3 0.5 0.2 0.5 1.0 0.1 1.6 0.8 0.0 0.2 0.0 0.2 0.2 0.4 0.1 0.2 0.2 0.1 0.5 0.5 0.2 513.4 0.4 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.3 0.3 0.6 0.2 0.0 0.1 0.3 0.2 0.3 0.6 0.1 1.4 0.0 0.1 0.1 0.0 1.3 0.4 0.3 0.8 0.5 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.4 0.8 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.4 0.9 0.6 0.1 0.0 0.7 0.3 0.1 0.1 0.0 0.0 0.3 0.1 1.3 0.7 1.3 0.0 0.2 0.9 0.3 0.4 0.3 0.2 0.9 0.8 0.3 0.1 0.7 0.7 0.3 0.6 2.3 0.1 0.6 0.5 0.2 0.2 0.3 0.4 0.3 0.3 0.3 0.2 0.5 0.3 0.9 0.3 1.5 0.3 0.5 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.2 2.1 0.4 0.2 0.4 0.1 0.1 0.5 0.5 1.6 0.8 0.5 0.5 0.6 0.5 0.6 0.1 0.6 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 85.7 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 320.0" "Group enriched" "Detected in many" 35 "Hepatocytes: 512.8;Proximal enterocytes: 465.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.8" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.2 0.0 0.3 0.3 0.1 0.8 0.2 0.1 0.3 0.3 3.7 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.3 320.0 0.1 0.1 0.2 0.0 0.2 0.8 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 11.7 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.8 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.0 1.1 5.5 0.7 0.5 0.7 1.3 2.8 7.3 1.1 1.4 0.4 2.8 0.7 1.8 2.1 0.1 0.6 2.9 1.9 0.7 3.1 0.8 0.6 0.6 1.2 0.0 6.5 0.6 0.1 0.3 4.1 1.4 0.0 0.7 5.7 512.8 0.1 11.8 9.4 7.6 0.0 5.6 0.0 13.6 0.0 0.4 0.0 0.0 0.1 0.7 0.0 5.0 4.9 0.7 11.3 1.5 0.4 0.6 465.2 0.5 1.3 2.3 0.0 0.4 2.1 0.8 0.4 0.6 1.1 0.4 1.0 0.1 3.4 0.3 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 44.7 0.1 0.1 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.8 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.2 0.0 0.0 3.9 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 6.4 0.1 1.7 1.9 0.0 0.0 0.6 1.9 3.3 0.0 0.2 0.0 1.0 0.0 0.2 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.7 0.1 2.4 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.2 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 920.2" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;SK-BR-3: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" 0.3 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.9 0.2 0.1 0.5 0.1 0.2 0.1 14.4 404.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 1.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.9 920.2 0.1 0.0 0.0 0.0 0.0 10.7 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 DAD1 OST2 ENSG00000129562 "Defender against cell death 1" P61803 14 22564907-22589224 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028882 Uncertain Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Endoplasmic reticulum" "HPA028882: AB_10602214" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.02e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (9.43e-3)" "unprognostic (3.06e-2)" "unprognostic (6.09e-2)" "unprognostic (1.99e-2)" "unprognostic (9.64e-2)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-3)" 204.0 229.3 209.2 159.1 224.4 129.0 224.0 236.2 259.4 229.6 252.2 197.7 165.8 184.3 473.8 187.0 230.5 190.8 202.6 211.4 238.0 296.8 275.7 183.4 169.6 240.2 218.7 174.5 200.2 254.1 201.6 141.8 238.7 145.5 209.9 86.2 286.3 205.5 156.6 137.2 173.8 206.6 237.2 165.3 197.0 150.7 219.2 211.6 272.8 197.5 191.0 200.0 163.4 252.0 373.3 344.7 274.6 375.8 740.2 529.9 238.3 387.0 473.0 340.5 478.1 219.6 520.1 233.7 242.1 453.1 381.4 330.0 291.1 375.7 543.3 319.8 265.1 228.5 180.9 886.0 514.5 321.2 315.8 395.8 498.7 356.0 454.4 383.1 506.2 220.9 176.4 532.1 509.9 459.3 153.6 391.4 169.7 816.1 557.8 211.7 232.4 306.7 503.2 306.1 211.5 263.4 294.9 416.1 445.9 328.7 251.4 323.1 381.1 291.8 232.2 358.2 248.3 391.2 502.6 308.5 263.8 225.5 431.0 532.4 421.9 460.9 528.4 371.9 518.9 527.2 543.8 501.4 401.0 477.1 564.8 497.6 481.5 437.2 332.3 783.9 560.3 941.8 209.2 224.4 236.2 259.4 211.4 238.0 240.2 218.7 238.7 237.2 219.2 252.0 357.9 160.3 161.7 15.0 183.9 198.3 188.3 581.8 149.7 25.1 201.0 274.6 173.8 187.3 315.2 255.6 27.1 260.9 204.6 174.8 215.2 525.4 196.8 270.3 242.9 267.8 135.7 130.2 10.6 415.2 383.1 276.5 145.2 255.6 302.6 150.8 187.7 231.9 350.3 21.9 11.0 242.3 360.1 146.2 224.8 101.5 214.3 166.8 330.8 8.4 217.3 216.8 198.8 18.1 42.5 396.8 160.7 199.0 408.6 172.5 244.8 420.8 393.7 42.6 151.2 141.5 291.0 300.3 128.1 179.6 215.8 289.0 211.7 266.6 183.8 174.4 DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 63.0;Early spermatids: 20.7;Excitatory neurons: 30.3;Horizontal cells: 25.2;Inhibitory neurons: 13.2;Late spermatids: 19.4;Microglial cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "U-2 OS: 4.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" 0.0 0.1 0.6 0.0 0.8 0.0 0.1 0.3 0.5 0.9 0.0 1.7 0.0 1.4 0.0 0.0 0.9 0.1 0.0 0.4 0.8 0.1 0.0 0.1 0.0 0.5 1.3 0.7 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.7 0.0 1.2 1.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.3 0.5 0.4 0.8 0.5 1.3 0.3 0.7 1.1 1.4 0.0 0.0 0.0 63.0 0.0 0.4 0.2 0.8 0.0 0.4 0.8 0.6 1.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.7 0.1 0.5 0.3 6.7 0.0 30.3 0.0 0.0 1.8 3.6 0.0 0.0 1.2 0.0 0.0 0.1 25.2 13.2 0.1 0.0 0.0 0.7 19.4 0.6 0.0 0.0 13.1 0.0 0.2 0.0 6.6 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.9 0.2 0.0 0.3 0.5 1.7 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 90.9;HBEC3-KT: 70.1;RT4: 93.5;T-47d: 103.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 4400000 "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 26.5 50.4 24.1 5.3 49.5 0.4 54.6 47.9 20.2 55.2 4.8 57.7 12.3 23.4 4.5 150.1 46.2 11.4 42.1 17.5 40.7 96.8 6.3 33.7 1.2 68.7 47.3 41.5 99.7 19.7 67.9 4.2 57.9 70.2 10.7 4.5 131.7 13.8 40.5 121.1 47.3 1.1 38.8 11.5 71.1 16.5 46.3 7.0 85.9 4.3 3.0 45.0 88.4 58.9 58.2 18.5 26.0 5.4 1.7 2.4 16.2 1.4 0.4 0.8 0.1 25.2 29.8 0.5 30.9 5.1 26.8 90.9 5.7 70.1 0.3 32.0 9.9 0.2 18.7 6.7 5.0 0.0 1.2 3.3 35.4 0.4 0.5 16.1 2.0 1.4 17.3 0.7 4.0 36.5 2.0 0.1 4.5 31.8 3.8 3.9 19.5 2.2 13.1 93.5 4.7 2.5 5.4 41.4 19.4 8.6 103.0 0.6 4.3 12.8 11.7 1.2 13.6 0.8 0.1 2.6 8.4 0.0 11.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 24.1 49.5 47.9 20.2 17.5 40.7 68.7 47.3 57.9 38.8 46.3 58.9 1.9 35.3 24.6 54.5 3.8 53.0 68.3 125.5 67.2 7.4 77.0 57.9 18.0 37.1 79.8 90.1 0.0 63.6 1.5 109.7 5.9 125.5 15.1 58.5 6.5 4.1 46.2 2.7 1.2 76.2 26.0 7.4 63.7 58.4 1.3 29.5 2.2 0.6 6.1 6.7 7.5 69.8 109.9 0.8 5.4 30.1 8.4 2.5 16.0 9.4 13.1 139.9 1.0 60.3 73.8 71.5 78.2 5.3 0.8 68.1 77.3 5.4 104.2 8.0 6.6 10.5 11.9 1.5 6.8 81.8 51.9 46.5 1.9 4.1 67.1 88.4 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 120.9;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 21.7 11.9 5.9 9.2 7.0 10.6 21.7 14.1 6.3 17.2 8.0 17.4 25.1 17.2 14.3 14.5 16.4 13.8 14.5 5.3 5.6 13.9 15.2 18.0 11.8 5.9 5.7 21.4 12.9 19.0 8.7 19.6 5.7 16.1 19.8 11.8 15.1 13.4 10.6 29.6 22.4 14.6 5.8 12.7 19.8 11.2 7.2 17.7 17.3 12.4 11.2 16.6 16.0 6.6 17.7 17.5 11.7 15.3 26.6 28.5 21.4 10.0 14.9 10.2 13.7 8.4 11.6 7.5 8.3 13.6 11.8 9.4 13.7 9.4 12.0 47.2 7.8 34.4 18.5 10.4 13.4 8.3 18.8 11.7 18.7 9.0 15.5 21.6 20.2 9.9 9.4 8.5 13.1 7.4 13.8 18.8 9.0 24.7 8.5 12.6 6.6 10.9 29.2 34.1 10.9 8.5 8.4 20.1 7.4 11.0 12.1 11.3 18.5 8.9 5.2 10.0 10.5 5.8 14.9 4.0 7.7 7.6 5.2 8.3 1.6 1.9 5.4 0.8 7.0 1.7 4.6 5.5 3.1 2.3 4.3 5.0 0.9 6.4 0.9 3.2 3.8 2.4 5.9 7.0 14.1 6.3 5.3 5.6 5.9 5.7 5.7 5.8 7.2 6.6 28.6 9.6 11.5 85.8 21.3 51.2 16.7 18.0 65.4 20.9 16.0 11.0 12.4 14.3 21.6 16.5 60.5 29.4 22.6 26.6 1.9 9.8 7.7 12.7 15.5 22.9 19.8 9.7 78.6 12.5 13.5 24.0 47.4 20.4 27.1 24.8 51.0 11.5 19.0 23.5 87.2 22.6 24.4 23.9 22.0 5.2 18.6 32.2 21.4 120.9 8.5 13.6 27.8 107.1 69.1 12.1 20.9 20.3 14.1 19.4 26.4 4.9 21.6 16.3 0.0 19.5 16.2 3.3 6.8 30.9 49.3 16.1 28.2 12.0 23.3 23.2 DENND5B MGC24039 ENSG00000170456 "DENN domain containing 5B" Q6ZUT9 12 31382226-31591136 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 152.8;Excitatory neurons: 217.3;Inhibitory neurons: 246.4;Oligodendrocyte precursor cells: 144.3;Oligodendrocytes: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SuSa: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038865 Approved Approved Nucleoli,Microtubules NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoli "HPA038865: AB_2676245" "unprognostic (5.41e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (7.23e-2)" "unprognostic (2.13e-1)" "unprognostic (1.16e-2)" "unprognostic (4.96e-2)" "unprognostic (3.14e-1)" "unprognostic (8.27e-2)" "unprognostic (5.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (2.60e-2)" 4.0 6.4 6.3 5.4 7.8 2.1 3.2 20.1 12.3 4.8 2.9 4.2 9.2 6.9 2.0 2.4 3.9 4.2 10.9 6.1 8.4 7.6 12.5 2.6 7.3 7.7 5.2 21.7 5.7 2.7 4.7 4.9 7.7 2.9 4.3 15.9 2.0 3.1 7.1 1.3 10.4 7.2 2.0 6.7 5.0 16.1 7.1 2.4 2.9 13.1 8.4 3.7 3.1 6.1 2.8 27.9 20.1 7.7 7.1 8.8 3.0 6.8 7.4 16.9 12.1 18.9 11.1 10.4 11.1 14.8 18.5 0.8 4.0 1.9 16.7 0.0 8.5 0.1 21.2 11.3 6.5 9.6 0.2 5.5 6.0 11.3 18.5 15.5 15.7 5.7 4.0 20.6 10.6 2.6 5.7 10.0 20.4 6.5 4.9 5.4 27.8 0.2 14.2 3.6 6.4 9.5 17.0 1.9 15.0 57.3 2.8 5.2 16.5 6.3 16.0 11.4 14.4 10.9 13.0 10.5 10.7 1.1 10.7 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.2 1.6 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.1 6.3 7.8 20.1 12.3 6.1 8.4 7.7 5.2 7.7 2.0 7.1 6.1 6.7 3.2 0.5 152.8 43.9 2.9 3.5 0.9 2.8 42.4 5.3 4.1 44.0 17.2 2.1 7.3 31.3 0.6 7.0 13.3 3.9 1.8 19.6 6.1 10.1 7.4 8.4 6.3 217.3 9.3 2.9 13.0 4.6 4.4 0.0 45.0 25.0 34.2 4.5 28.6 246.4 3.1 2.0 4.5 5.8 8.3 8.4 3.8 23.2 74.9 2.5 12.9 1.0 144.3 121.0 7.9 3.6 10.5 72.6 2.4 33.2 12.0 2.2 26.8 6.6 12.9 10.0 32.0 18.2 0.2 1.4 0.7 2.3 15.5 4.4 1.2 DERL1 "DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577" ENSG00000136986 "Derlin 1" Q9BUN8 8 123013170-123042302 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 225.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 825.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016562, CAB037269" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB037269: AB_609868, HPA016562: AB_1847611" "prognostic unfavorable (2.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (9.48e-2)" "unprognostic (4.21e-3)" "unprognostic (2.76e-1)" "unprognostic (1.28e-3)" "unprognostic (4.42e-2)" "unprognostic (5.38e-2)" "unprognostic (1.41e-3)" "unprognostic (4.35e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.88e-3)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" 69.1 47.6 15.2 53.7 16.4 104.1 34.1 20.2 18.2 26.6 26.6 50.0 47.9 29.4 31.4 35.4 29.4 32.9 41.3 17.9 18.3 30.8 77.5 37.1 48.7 15.7 16.4 38.1 31.6 26.9 23.0 28.0 15.7 27.0 42.8 29.6 29.6 28.7 73.3 23.6 47.0 34.4 16.7 40.0 38.5 32.1 18.0 27.2 42.4 49.1 55.5 41.8 22.5 19.5 130.8 93.9 55.7 72.6 98.3 72.8 47.1 108.9 72.1 68.7 85.1 59.7 126.9 150.7 129.8 87.4 81.2 107.0 51.8 69.3 97.4 174.9 57.6 157.2 62.9 51.6 89.2 62.2 111.0 66.9 87.8 76.0 89.8 62.5 62.8 60.6 95.9 193.7 78.7 254.8 68.5 39.4 42.1 166.4 82.5 68.3 46.2 252.1 182.2 92.1 60.5 89.8 109.9 825.1 68.6 59.6 97.3 55.4 74.2 82.2 154.1 74.1 102.1 239.5 444.6 136.5 135.4 76.4 79.4 73.1 60.7 72.6 89.3 75.7 93.0 69.8 59.5 74.0 49.5 56.1 41.0 64.0 42.1 77.8 77.9 56.6 80.0 83.3 15.2 16.4 20.2 18.2 17.9 18.3 15.7 16.4 15.7 16.7 18.0 19.5 38.6 32.1 25.9 12.4 78.3 42.3 41.8 57.3 26.7 22.6 38.3 21.3 28.1 17.2 44.8 29.5 20.9 41.0 67.6 43.3 9.8 87.7 85.5 18.9 32.3 39.2 30.5 41.0 11.5 75.4 71.4 43.8 26.5 31.2 42.6 24.0 39.3 75.9 68.0 18.5 12.8 62.2 42.7 49.4 44.2 19.9 24.5 45.6 60.5 14.0 47.6 25.5 59.8 17.6 19.1 68.4 40.6 25.6 225.0 63.7 56.6 28.0 31.3 25.6 46.0 32.7 77.6 75.4 40.3 41.0 50.7 78.0 69.8 34.8 37.5 64.4 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1129.5;liver: 623.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1031.9" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 58.3 1129.5 35.7 19.8 58.5 1.6 104.8 125.3 73.0 54.9 30.4 55.6 62.2 13.1 1.6 296.1 60.4 42.2 18.0 55.9 63.9 48.6 623.5 215.9 9.4 216.2 91.3 28.5 30.5 157.9 17.0 21.6 158.9 128.6 40.5 15.8 136.2 8.3 197.7 247.6 29.6 12.6 129.3 134.1 98.9 74.2 87.9 10.1 15.4 11.1 33.9 13.5 103.9 280.7 342.1 58.5 210.6 257.1 1031.9 219.0 50.5 94.8 160.3 130.7 268.6 341.6 210.2 55.3 191.5 82.4 427.4 319.2 250.5 501.3 118.3 8.3 159.6 303.3 131.8 421.7 168.9 126.7 68.2 161.0 429.0 397.6 74.7 66.7 67.2 124.5 224.7 0.2 50.2 143.5 25.8 111.4 592.0 90.7 164.2 0.3 54.2 166.3 735.3 257.1 144.5 53.2 185.0 337.5 123.1 221.6 441.5 143.3 62.2 45.3 130.0 66.1 183.9 22.7 55.0 91.2 32.8 215.3 60.4 5.1 1.5 0.7 6.0 1.8 0.3 3.7 2.5 2.6 5.2 1.3 2.2 2.9 0.0 2.7 0.7 3.0 0.4 4.4 35.7 58.5 125.3 73.0 55.9 63.9 216.2 91.3 158.9 129.3 87.9 280.7 6.2 298.1 682.3 12.4 13.3 31.5 17.3 150.6 79.1 9.7 87.9 33.1 15.3 145.8 205.2 68.0 0.0 35.2 6.4 133.3 3.9 55.3 22.9 14.5 5.8 13.5 24.0 71.6 14.5 76.5 34.4 17.5 38.7 44.7 32.2 26.4 111.0 1091.4 28.0 5.0 8.7 39.2 69.2 68.9 8.2 77.2 14.0 9.4 14.2 1.9 6.8 3.6 2.1 5.5 62.6 48.6 27.7 7.9 1.8 52.4 22.6 14.4 136.3 6.4 0.0 1.5 23.2 5.4 14.7 145.4 80.4 30.6 10.6 442.4 35.2 45.2 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DHRS7B "CGI-93, DKFZp566O084, MGC8916, SDR32C1" ENSG00000109016 "Dehydrogenase/reductase 7B" Q6IAN0 17 21123364-21193265 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012132, HPA016873" Uncertain Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cell Junctions, Cytosol" "HPA012132: AB_1847658, HPA016873: AB_1847657" "unprognostic (1.90e-1)" "unprognostic (3.16e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.98e-8)" "unprognostic (9.83e-2)" "unprognostic (1.18e-1)" "unprognostic (3.46e-1)" "unprognostic (1.45e-1)" "unprognostic (5.02e-3)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.81e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.20e-2)" "unprognostic (6.26e-2)" "unprognostic (9.20e-2)" "unprognostic (3.97e-1)" 19.0 18.8 18.5 8.1 18.6 2.9 19.2 19.6 28.3 17.8 19.9 15.1 15.6 11.4 25.7 12.8 15.9 11.9 22.2 18.6 19.2 22.8 20.2 13.4 7.7 19.3 19.2 8.4 20.2 32.9 7.9 13.2 19.4 15.1 15.8 10.8 18.3 10.2 30.8 18.7 14.5 9.6 19.3 9.2 18.1 24.0 18.3 6.8 16.6 19.5 9.0 12.4 11.1 20.7 17.2 19.9 7.1 15.6 18.5 12.7 12.4 16.0 8.9 11.4 20.7 25.2 17.6 7.2 23.8 13.7 9.0 23.7 10.6 26.2 16.1 13.8 33.9 9.9 13.8 21.8 10.2 5.5 7.0 10.0 17.0 14.6 22.1 5.6 11.3 12.5 6.0 8.6 13.5 35.2 6.0 21.6 9.9 55.4 8.5 10.0 18.8 12.7 39.1 20.5 3.9 8.3 19.8 17.4 17.9 56.8 11.7 11.2 5.6 9.4 6.4 28.7 18.3 4.7 7.9 13.6 14.9 20.3 14.4 19.2 34.3 29.3 6.7 33.9 6.0 7.6 6.5 4.6 21.6 5.9 7.0 6.1 25.0 8.4 40.8 9.4 10.9 14.4 18.5 18.6 19.6 28.3 18.6 19.2 19.3 19.2 19.4 19.3 18.3 20.7 31.1 16.0 18.1 29.4 11.9 16.3 26.7 59.0 11.4 21.3 19.8 17.4 14.1 25.8 38.5 29.5 31.3 52.9 11.3 25.9 17.6 47.2 69.5 38.1 13.6 23.7 7.2 21.9 32.9 39.0 31.8 18.9 14.3 22.2 8.8 13.8 27.5 20.5 29.4 18.5 37.3 28.5 48.8 17.9 15.5 24.4 22.4 14.3 19.6 14.0 20.8 27.6 22.6 36.7 36.2 30.0 24.8 35.0 10.5 29.0 44.4 25.2 50.7 40.1 6.6 15.1 18.2 71.5 22.3 10.7 18.6 51.6 11.2 27.3 22.2 25.1 DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly complex 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 500.8;Hofbauer cells: 221.7;Proximal tubular cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA014585 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" 10.6 11.9 16.8 7.7 17.0 6.2 12.4 17.5 21.0 9.3 9.0 12.6 9.8 10.0 11.8 9.3 11.0 6.3 25.4 16.3 17.8 15.9 10.2 7.2 10.0 15.2 15.0 13.2 9.2 21.8 12.3 8.1 15.6 11.9 9.9 9.0 14.3 11.6 43.1 8.5 9.1 8.1 15.1 10.4 10.7 7.0 16.0 20.6 11.8 29.8 8.9 11.5 8.3 16.9 18.5 21.8 19.7 12.3 15.4 19.1 13.3 11.0 7.7 11.5 10.4 9.9 11.3 27.1 5.6 9.8 15.0 9.8 21.2 18.8 11.6 16.2 24.3 49.3 32.7 31.8 15.6 17.2 6.7 24.1 13.2 9.1 13.9 10.6 11.0 24.3 9.2 5.6 12.2 15.7 25.1 39.7 17.5 15.6 10.5 19.0 11.1 16.4 13.2 17.6 31.5 17.6 12.0 8.0 14.1 13.5 10.5 10.5 14.0 8.8 14.2 11.6 7.7 7.0 12.0 14.5 7.4 14.3 9.0 2.0 10.1 4.5 11.5 12.2 17.4 26.5 15.7 12.3 12.6 22.5 20.5 16.5 1.6 20.8 9.8 13.1 19.9 19.6 16.8 17.0 17.5 21.0 16.3 17.8 15.2 15.0 15.6 15.1 16.0 16.9 42.2 70.5 48.5 0.0 15.7 0.0 0.0 0.0 0.0 0.0 69.5 81.5 0.0 0.0 24.1 101.2 0.0 113.6 13.9 0.0 500.8 94.2 0.0 81.4 64.3 30.0 0.0 0.0 0.0 90.7 96.3 32.8 0.0 58.6 27.8 127.7 0.0 0.0 221.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 62.4 0.0 0.0 3.1 0.0 0.0 254.7 70.7 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 55.4 17.3 79.3 0.0 0.0 DNAJC25 bA16L21.2.1 ENSG00000059769 "DnaJ heat shock protein family (Hsp40) member C25" Q9H1X3 9 111631334-111654351 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 32.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019122 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA019122: AB_1853155" "unprognostic (3.07e-1)" "unprognostic (7.42e-2)" "unprognostic (8.94e-3)" "prognostic favorable (3.73e-4)" "unprognostic (2.08e-2)" "unprognostic (5.66e-2)" "unprognostic (1.60e-2)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (9.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.09e-2)" "unprognostic (2.52e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-1)" "unprognostic (8.30e-2)" "unprognostic (5.19e-2)" 3.3 5.2 1.0 2.3 1.1 1.0 2.0 1.0 1.9 1.5 2.5 3.0 2.9 1.7 4.4 1.5 1.8 2.1 2.5 1.1 1.0 5.1 32.1 1.3 0.7 1.4 1.2 1.4 2.9 4.2 1.5 2.7 1.2 3.7 1.6 0.6 4.2 2.2 2.2 1.0 2.4 1.7 0.9 0.7 2.4 1.4 1.0 0.2 2.2 1.7 0.8 3.0 1.3 1.0 2.7 2.0 1.3 2.3 14.1 6.2 5.3 10.4 4.8 3.9 3.7 3.7 1.6 2.4 4.0 7.0 6.1 8.5 1.5 2.9 3.7 1.9 2.0 2.4 0.0 8.0 4.5 4.5 3.3 5.3 8.2 3.0 5.6 3.0 3.3 1.3 4.9 1.8 5.0 2.9 1.3 0.2 2.3 5.1 4.9 2.3 7.3 2.2 8.2 2.8 2.3 1.2 5.7 7.7 3.6 2.3 4.1 0.8 6.5 4.7 2.3 12.9 6.0 3.6 6.0 1.3 8.1 2.1 4.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.0 1.1 1.0 1.9 1.1 1.0 1.4 1.2 1.2 0.9 1.0 1.0 9.9 6.4 11.9 0.0 8.3 10.6 16.2 13.8 6.8 7.9 14.1 12.4 13.9 8.6 16.0 11.0 20.9 14.2 16.7 16.2 13.7 17.1 10.8 18.6 18.2 7.9 17.3 3.0 0.0 16.3 24.7 15.3 10.2 19.5 1.3 8.8 6.4 85.3 12.1 13.5 0.0 21.3 6.1 6.4 10.2 2.5 10.2 10.0 12.4 0.0 6.7 4.6 5.2 0.0 0.0 11.7 7.3 10.1 22.6 29.4 21.7 13.5 18.9 19.9 13.1 13.3 15.7 29.5 16.6 7.0 9.2 13.8 8.8 10.6 15.0 22.7 DPM2 "MGC111193, MGC21559" ENSG00000136908 "Dolichyl-phosphate mannosyltransferase subunit 2, regulatory" O94777 9 127935099-127937854 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Congenital disorder of glycosylation, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 202.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064623 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA064623: AB_2685303" "unprognostic (8.30e-3)" "unprognostic (1.07e-2)" "unprognostic (9.84e-3)" "prognostic favorable (2.20e-4)" "unprognostic (3.67e-1)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.91e-1)" "unprognostic (1.37e-1)" "unprognostic (6.62e-2)" "unprognostic (5.55e-3)" "unprognostic (1.35e-1)" "unprognostic (1.51e-2)" "unprognostic (5.71e-3)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" 21.4 20.6 54.1 19.4 53.2 39.6 27.4 50.5 66.8 31.4 50.0 27.6 23.9 17.9 38.1 25.5 43.1 19.7 16.0 56.0 52.7 22.0 29.7 29.2 24.0 53.2 55.0 20.7 58.6 53.4 12.2 26.9 52.7 24.5 25.7 13.2 50.1 26.8 8.2 29.5 20.1 28.4 50.7 18.5 39.9 15.4 54.2 26.6 38.2 12.0 29.3 25.0 9.6 52.2 49.5 85.5 42.1 57.2 75.1 59.4 40.6 61.3 55.7 63.9 44.2 58.1 79.7 38.8 38.0 90.1 91.8 85.4 47.3 88.1 31.2 71.7 74.5 46.4 98.5 66.1 88.8 75.4 51.1 57.5 78.0 93.5 101.2 44.9 65.8 67.2 106.2 84.9 76.7 161.8 55.8 78.0 79.1 169.7 79.4 43.0 54.6 212.7 79.1 28.8 39.3 95.8 63.8 75.4 53.0 27.3 95.1 48.2 43.5 56.1 43.4 72.0 64.5 93.3 134.4 32.5 113.1 52.8 76.6 52.3 67.8 57.6 86.6 75.7 72.8 99.3 62.1 75.9 77.3 94.3 47.8 61.6 28.1 77.5 73.0 88.5 55.2 60.9 54.1 53.2 50.5 66.8 56.0 52.7 53.2 55.0 52.7 50.7 54.2 52.2 29.9 28.9 42.5 6.5 27.5 27.0 34.1 58.2 18.8 25.3 52.4 57.7 12.4 38.6 42.8 40.5 16.7 86.9 25.1 40.6 45.0 61.2 9.6 28.3 39.9 33.1 32.4 202.7 9.7 59.4 105.8 38.6 44.9 33.5 29.2 31.1 33.9 33.2 83.7 38.7 9.2 53.6 42.7 25.0 22.1 11.6 26.4 30.0 32.0 7.5 49.8 35.0 39.1 6.0 10.0 58.7 36.2 20.3 62.0 64.5 44.5 47.3 24.9 22.1 6.6 16.6 32.5 19.1 22.5 36.8 34.5 65.0 28.5 41.2 43.8 40.7 DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024339, HPA024780" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA024339: , HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" 11.5 12.3 7.3 6.6 10.5 5.1 12.5 9.7 9.4 13.6 8.0 8.6 6.7 12.3 10.5 7.6 11.2 10.0 15.4 6.5 10.1 14.5 15.8 9.1 6.9 9.9 9.0 16.7 9.4 26.4 6.4 12.6 10.3 11.6 9.0 13.0 10.2 9.0 7.2 9.4 7.9 9.5 9.6 11.1 13.1 9.6 8.9 7.0 16.1 9.3 5.8 8.6 8.5 14.4 24.4 15.5 26.1 16.4 25.9 33.3 14.4 21.5 20.3 19.8 19.4 7.3 35.0 5.4 25.8 20.8 13.3 25.0 16.0 16.9 32.7 12.2 12.8 25.3 15.1 12.2 30.1 10.9 5.1 22.2 14.0 16.8 16.2 23.2 24.3 16.0 18.0 9.0 23.3 15.3 20.9 20.5 10.2 27.9 17.2 14.8 17.9 10.9 19.1 18.9 12.8 28.7 17.2 3.6 16.8 15.9 22.8 13.6 24.0 20.5 12.6 23.1 18.1 9.9 13.1 14.8 15.4 18.7 29.6 0.7 0.5 0.0 1.0 0.6 1.4 1.2 1.0 1.6 1.0 0.3 1.1 1.4 0.4 1.4 0.6 1.2 0.4 0.7 7.3 10.5 9.7 9.4 6.5 10.1 9.9 9.0 10.3 9.6 8.9 14.4 21.1 16.0 16.3 20.5 6.3 9.8 14.1 11.6 15.9 19.6 16.2 12.1 26.0 11.5 13.0 40.5 4.2 16.7 3.7 8.5 1.9 8.9 2.1 13.7 20.3 19.0 7.3 9.7 13.2 10.0 11.9 20.4 12.2 13.7 3.8 23.1 65.0 27.5 9.6 13.5 18.3 11.5 10.2 14.8 11.9 5.0 17.4 8.3 10.6 25.3 5.5 11.9 9.2 23.6 39.7 13.0 6.4 18.4 7.9 15.6 10.7 10.7 18.8 17.6 6.6 13.4 14.9 11.9 9.8 16.6 12.1 9.2 7.8 32.6 12.0 14.1 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 112.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014764 Uncertain "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 27.8 10.7 3.6 26.8 4.5 18.4 18.3 3.9 4.4 13.8 10.4 7.7 6.4 10.5 8.3 13.7 14.6 14.9 12.4 3.2 4.3 8.6 11.3 15.3 16.4 7.0 5.8 13.8 3.8 11.1 6.0 23.1 5.6 8.5 8.0 3.5 6.9 10.2 6.9 13.8 9.0 15.0 4.6 18.6 6.4 6.1 8.5 10.3 6.6 10.7 9.7 19.7 14.3 5.9 32.7 7.0 23.6 22.2 62.0 40.7 26.5 37.6 88.2 46.4 67.4 0.2 8.9 0.9 3.3 66.3 46.4 60.8 3.3 88.7 60.1 33.9 14.6 2.2 9.8 0.3 69.0 1.5 1.7 86.8 37.4 51.5 50.0 24.0 27.7 8.3 0.8 14.4 22.4 1.0 4.4 1.8 12.7 0.2 1.8 5.6 21.6 15.6 30.4 2.2 7.8 5.9 36.4 0.1 0.8 16.2 0.3 3.9 10.5 46.4 13.4 11.8 30.6 3.1 1.1 1.6 24.6 4.0 5.5 0.4 2.0 0.1 0.6 2.5 0.3 2.0 0.5 0.3 5.9 2.1 0.6 0.3 1.6 0.1 1.6 2.7 0.1 0.8 3.6 4.5 3.9 4.4 3.2 4.3 7.0 5.8 5.6 4.6 8.5 5.9 9.4 16.0 4.1 64.9 15.4 52.0 26.4 42.2 78.6 6.3 7.4 10.7 8.3 2.8 20.7 3.7 0.0 2.9 16.5 0.3 7.9 4.8 52.2 11.0 21.9 15.4 1.2 11.4 46.8 8.5 7.0 73.7 3.6 3.1 22.8 100.9 56.4 5.7 39.8 1.7 48.9 0.6 8.2 83.6 77.1 24.9 55.0 112.2 10.6 51.5 79.4 3.4 5.2 73.4 86.4 13.6 0.4 30.1 8.9 32.0 0.4 7.7 30.3 3.0 32.9 16.4 33.4 6.1 5.5 76.6 39.9 4.9 14.0 17.2 1.0 51.0 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DUOXA1 "FLJ32334, mol, NIP, NUMBIP" ENSG00000140254 "Dual oxidase maturation factor 1" Q1HG43 15 45117367-45129938 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 189.0;skin 1: 91.6;thyroid gland: 111.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 118.0;Club cells: 35.5;Glandular and luminal cells: 47.7;Respiratory ciliated cells: 36.9;Squamous epithelial cells: 53.6;Urothelial cells: 44.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041578 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA041578: AB_10795691" "unprognostic (1.28e-1)" "unprognostic (1.32e-3)" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (2.71e-1)" "unprognostic (6.87e-3)" "unprognostic (1.03e-1)" "unprognostic (4.45e-2)" "unprognostic (6.69e-2)" "unprognostic (3.68e-2)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.17e-5)" "unprognostic (8.11e-2)" "unprognostic (1.12e-2)" "unprognostic (4.69e-2)" "unprognostic (5.36e-2)" 1.1 5.0 0.2 1.3 0.5 0.1 4.0 0.7 1.1 32.1 0.0 0.9 0.8 4.6 49.3 189.0 5.7 4.3 2.1 0.5 0.3 0.8 0.3 64.3 0.1 0.6 0.1 1.1 0.4 5.0 0.7 0.8 0.8 21.6 0.5 0.1 27.5 12.0 0.5 91.6 0.8 0.2 0.1 0.1 43.6 0.2 0.7 0.7 111.1 0.0 17.9 23.3 77.4 2.9 10.6 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 103.9 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 14.5 0.0 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.7 1.1 0.5 0.3 0.6 0.1 0.8 0.1 0.7 2.9 0.0 60.9 118.0 1.0 0.0 9.4 18.8 26.9 18.2 0.6 1.4 1.7 0.5 0.0 35.5 0.0 2.1 2.4 0.0 3.3 0.0 2.0 0.1 28.7 4.0 0.8 3.0 0.0 0.7 3.1 0.1 1.6 8.6 47.7 1.3 0.3 0.0 0.0 0.3 0.0 0.4 0.1 4.1 0.0 1.2 0.0 0.3 0.8 0.0 0.0 0.6 0.1 0.0 0.5 1.8 1.9 3.3 0.0 0.0 13.4 0.0 0.0 36.9 0.1 0.0 0.7 1.1 0.0 0.9 53.6 21.9 3.0 0.6 0.1 0.4 44.2 EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" 21.9 59.7 6.6 12.1 6.5 20.0 23.2 7.0 8.9 37.0 7.5 24.1 14.2 20.4 6.6 62.3 25.5 11.1 8.7 6.7 7.3 14.8 99.3 19.1 11.0 6.8 6.8 33.3 47.7 10.5 10.3 11.2 6.9 21.3 16.3 4.4 27.9 13.5 5.2 33.7 14.3 13.3 7.8 14.4 27.5 11.0 7.9 10.3 16.1 2.5 11.0 23.8 47.6 8.4 46.7 34.9 21.0 88.5 26.0 66.4 37.5 48.5 33.1 30.9 25.0 66.8 65.1 57.9 21.6 23.7 27.1 93.7 38.3 47.4 45.0 46.4 126.8 43.7 23.4 83.3 75.2 69.4 35.0 77.7 100.4 25.6 68.1 49.9 53.6 61.5 36.7 23.0 40.2 25.0 27.4 124.8 72.4 153.2 78.2 58.5 11.7 89.0 66.4 15.2 19.5 50.1 18.0 62.1 21.6 21.7 54.4 54.0 24.6 23.4 23.2 20.2 40.7 14.9 41.2 46.7 11.2 68.6 21.6 2.4 3.0 0.8 2.4 3.6 6.8 4.3 4.8 5.0 5.0 5.4 7.1 4.1 6.4 4.1 3.9 3.3 3.7 1.4 6.6 6.5 7.0 8.9 6.7 7.3 6.8 6.8 6.9 7.8 7.9 8.4 75.5 35.3 23.1 9.8 46.5 108.6 157.6 17.4 115.5 7.9 139.8 192.1 5.4 104.4 17.4 23.9 8.4 32.3 25.5 26.5 41.1 61.2 13.3 61.5 90.6 76.8 27.8 65.6 8.0 52.1 37.1 56.9 56.6 50.0 17.8 64.9 78.9 305.3 38.5 1.7 11.6 80.1 8.2 45.8 36.5 10.0 94.1 27.4 46.2 8.4 30.9 23.6 36.0 8.0 5.1 41.0 42.0 70.0 79.3 116.6 16.5 62.3 8.5 8.4 19.7 57.7 52.7 26.9 17.2 208.6 154.6 15.2 40.3 194.2 133.6 108.9 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EDRF1 "C10orf137, DKFZp586F1019, FLJ21617" ENSG00000107938 "Erythroid differentiation regulatory factor 1" Q3B7T1 10 125719515-125764143 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031820 Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA031820: AB_10600753" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.64e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-2)" "unprognostic (8.84e-4)" "unprognostic (4.76e-3)" "unprognostic (8.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.63e-3)" "unprognostic (4.62e-2)" "prognostic unfavorable (3.16e-5)" "unprognostic (3.44e-3)" "unprognostic (5.51e-2)" "unprognostic (1.38e-1)" "unprognostic (7.68e-3)" 4.1 4.0 2.0 6.1 2.7 21.8 5.6 5.3 2.9 5.6 2.7 4.0 5.0 7.4 4.9 4.7 4.6 4.1 5.1 2.9 2.0 3.6 2.8 4.2 9.7 1.7 1.7 8.0 7.2 4.3 2.9 5.7 2.3 6.8 5.2 4.6 12.3 4.1 5.7 5.1 4.5 5.2 1.5 5.4 4.7 15.1 1.7 9.4 5.2 5.1 8.2 4.4 3.3 4.1 12.6 11.7 15.4 16.5 7.2 10.0 7.8 14.8 13.6 16.3 18.5 15.7 10.4 16.5 6.9 9.6 9.5 15.3 22.6 4.7 18.0 10.3 18.3 12.0 12.5 8.9 9.6 17.0 12.1 6.5 6.0 16.2 8.1 15.6 7.8 8.9 11.1 11.2 10.6 5.3 16.9 11.8 20.6 7.7 10.2 14.0 13.2 9.7 6.5 7.2 7.6 14.9 10.7 5.9 10.1 13.9 10.3 6.8 5.4 8.8 9.6 12.4 17.1 15.0 11.4 26.1 9.3 8.8 5.0 5.9 2.3 1.4 2.7 2.0 3.4 3.1 2.2 2.5 3.0 2.3 2.2 2.8 2.9 2.9 1.3 2.9 3.1 1.4 2.0 2.7 5.3 2.9 2.9 2.0 1.7 1.7 2.3 1.5 1.7 4.1 12.4 12.8 9.7 26.1 19.1 5.9 5.7 5.1 15.4 23.9 9.3 8.4 12.9 8.6 9.0 11.0 33.3 6.7 28.5 5.1 0.0 4.3 145.1 11.2 14.6 9.5 4.2 7.6 40.9 7.2 6.0 12.1 17.3 27.2 20.3 24.7 7.5 7.0 4.1 20.2 31.7 7.5 4.1 7.7 4.2 61.5 21.1 9.2 7.2 22.5 12.2 9.1 13.4 22.1 36.2 8.3 4.9 19.9 27.1 6.6 7.1 2.7 8.6 24.4 6.6 13.0 11.0 26.8 21.4 10.6 8.2 4.5 20.1 18.5 7.3 5.2 EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 461.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 760.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" 53.4 32.6 61.1 36.2 62.5 23.2 72.6 59.7 72.4 51.3 59.8 77.8 49.6 46.2 57.4 80.8 50.8 46.3 55.7 60.2 61.5 61.0 248.4 45.0 28.4 60.2 62.5 42.4 101.8 461.9 30.6 48.5 60.2 49.6 80.4 39.4 75.3 58.0 119.5 70.2 49.3 62.5 62.4 30.5 59.7 33.1 64.4 35.3 40.5 104.6 42.3 78.9 48.4 61.0 156.6 115.6 129.5 160.5 207.7 155.9 162.4 159.6 116.8 104.3 93.4 178.9 303.4 158.0 264.0 146.5 110.8 176.1 199.0 326.8 135.2 42.0 142.6 760.9 77.2 179.9 154.1 170.9 78.4 147.5 292.7 157.4 230.2 102.8 223.9 85.1 351.1 61.1 149.4 113.8 79.0 96.4 173.6 398.3 139.5 113.9 155.4 132.8 177.0 272.4 120.1 116.9 187.1 215.5 63.4 212.3 436.4 165.7 195.2 133.8 93.3 94.7 128.7 39.7 84.8 200.5 58.5 256.1 182.2 4.3 7.0 5.9 7.2 6.7 7.2 8.4 5.7 9.0 10.9 6.3 8.1 6.7 0.8 6.5 4.9 14.5 9.1 5.3 61.1 62.5 59.7 72.4 60.2 61.5 60.2 62.5 60.2 62.4 64.4 61.0 73.5 32.1 38.3 13.4 34.8 120.6 130.3 132.6 120.1 58.9 148.8 100.6 61.9 124.4 69.5 110.3 37.5 166.9 32.4 66.4 144.8 178.6 31.1 34.4 59.3 87.1 98.4 102.7 25.1 181.8 201.2 80.1 87.7 46.5 27.3 76.2 74.6 575.0 110.5 82.4 24.0 115.3 105.8 49.8 96.1 49.7 71.4 40.9 90.7 11.2 40.9 107.1 50.4 13.0 23.0 182.1 67.6 72.2 79.1 270.0 68.5 122.7 43.9 36.9 46.0 60.8 80.1 95.9 112.3 176.3 181.4 140.1 31.0 71.3 135.7 189.4 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627464 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 19.6" "Cell type enhanced" "Detected in many" "Plasma cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 46.8;U-266/70: 44.0;U-698: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 3.3 3.1 0.8 4.0 1.1 2.6 1.6 1.6 1.4 2.3 1.6 4.7 6.2 1.9 1.0 1.6 1.3 1.4 1.5 0.8 1.5 2.0 1.9 1.8 3.2 1.0 1.2 1.9 19.6 3.4 1.1 3.2 0.9 4.0 1.8 0.1 9.7 1.2 2.0 1.4 5.0 0.9 1.5 3.1 12.3 1.0 1.2 1.3 3.5 0.0 2.3 1.9 1.8 2.1 8.7 3.3 1.2 4.3 2.8 2.0 15.9 12.4 1.1 0.7 2.1 3.5 2.9 46.8 8.0 1.3 3.1 7.2 1.6 1.3 1.1 25.3 7.1 4.6 1.7 2.0 1.1 3.9 12.3 0.1 1.5 0.7 2.0 0.8 1.4 4.9 3.0 8.7 0.6 4.4 5.5 2.2 6.2 2.7 7.2 25.1 7.0 8.2 1.3 5.0 5.6 9.9 6.3 6.5 8.2 1.7 2.2 4.4 3.9 2.5 5.5 10.8 7.1 44.0 24.4 31.0 4.6 4.2 6.2 0.0 0.1 0.1 0.3 0.0 0.2 1.0 0.2 0.8 0.1 1.9 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 1.1 1.6 1.4 0.8 1.5 1.0 1.2 0.9 1.5 1.2 2.1 9.2 9.6 7.5 14.7 43.8 20.3 8.9 7.2 26.7 8.4 14.7 8.9 8.2 17.2 7.2 12.9 8.4 4.1 13.4 14.0 0.0 3.7 0.1 18.4 18.3 7.6 13.7 1.7 31.3 6.5 6.9 15.2 40.2 39.2 1.3 4.4 8.9 11.8 4.6 1.7 39.0 30.1 14.2 5.1 41.2 0.7 7.5 27.7 32.0 21.5 3.9 3.0 9.2 20.1 26.2 7.0 7.7 5.7 121.3 13.0 5.4 2.9 7.7 2.3 0.0 13.4 9.4 3.1 3.6 23.8 18.3 6.7 12.8 3.5 6.8 16.6 ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.4;Hepatocytes: 102.0;Inhibitory neurons: 78.5;Oligodendrocytes: 77.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 2.4;MAIT T-cell: 2.6;memory CD4 T-cell: 1.0;memory CD8 T-cell: 1.3;naive CD8 T-cell: 1.0;NK-cell: 3.3" "Group enriched" "Detected in many" 21 "NK-cells: 3.3;T-cells: 2.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favorable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" 12.2 8.7 4.6 2.9 5.2 4.0 7.4 5.2 7.9 4.2 1.5 11.5 8.5 3.1 2.1 18.0 2.1 3.2 4.2 4.9 5.0 4.0 36.2 3.1 0.7 5.8 5.4 1.5 2.0 6.4 4.0 1.7 6.0 1.9 10.2 12.1 4.1 2.3 1.0 15.3 6.3 3.7 5.8 1.6 13.6 0.9 5.3 1.8 1.8 0.5 2.3 6.8 5.7 7.8 24.1 14.5 57.8 12.9 31.6 32.6 24.6 16.8 9.5 6.4 16.4 7.6 45.5 2.5 1.3 13.3 22.0 21.5 46.8 52.2 13.6 9.5 14.8 33.9 17.3 17.9 19.6 30.4 18.8 30.0 10.2 34.9 13.5 21.5 11.9 3.4 33.8 57.0 12.6 10.5 7.1 2.6 25.0 15.3 7.2 4.3 24.1 7.2 37.2 20.3 11.0 23.3 9.9 57.9 9.1 24.3 10.0 0.3 5.9 13.2 15.5 20.4 21.4 2.7 11.3 57.9 20.8 0.0 2.8 0.1 0.0 0.0 2.4 0.0 2.6 0.0 1.0 1.3 0.0 0.0 0.3 1.0 0.1 3.3 0.0 0.0 0.1 0.4 4.6 5.2 5.2 7.9 4.9 5.0 5.8 5.4 6.0 5.8 5.3 7.8 2.1 0.0 7.8 51.2 1.6 1.8 3.0 8.6 2.8 24.4 3.8 2.8 3.2 8.6 9.8 11.0 37.5 2.5 8.9 38.1 5.9 13.0 7.6 3.5 11.1 2.2 3.0 34.9 83.4 8.2 26.8 6.9 30.5 6.3 6.3 8.3 4.2 102.0 1.9 26.9 78.5 14.4 8.2 3.0 0.3 3.9 1.2 0.7 0.0 18.7 0.1 5.5 18.6 56.3 77.3 16.6 24.8 1.2 2.9 2.5 7.1 6.9 2.9 16.3 6.6 6.4 7.5 0.2 1.5 19.9 7.0 2.1 9.6 11.8 22.4 5.1 EMC3 TMEM111 ENSG00000125037 "ER membrane protein complex subunit 3" Q9P0I2 3 9962537-10011116 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 360.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042372 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "HPA042372: AB_10795609" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.59e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-3)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.81e-6)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.71e-2)" "unprognostic (5.58e-2)" 71.1 41.1 26.5 28.9 27.6 65.7 33.3 28.5 29.9 26.1 29.7 40.6 37.4 23.2 26.9 46.1 28.9 27.9 34.3 29.2 29.4 40.3 65.7 36.1 22.7 31.0 29.5 22.5 43.6 70.5 17.2 20.3 30.4 25.8 36.0 24.2 42.8 32.0 78.5 33.6 37.3 32.0 28.3 23.1 35.3 48.5 28.8 27.2 39.9 46.7 28.5 40.7 25.1 30.4 48.9 100.7 37.4 22.5 232.6 90.3 125.1 98.1 84.6 60.1 64.8 69.5 75.6 38.7 69.8 111.9 115.2 66.7 64.2 58.3 61.7 105.2 64.3 63.6 69.9 46.5 100.4 71.8 68.2 107.4 102.5 104.9 60.1 76.5 75.6 41.8 82.0 109.2 90.2 119.5 38.3 35.6 41.5 103.2 68.7 49.0 52.4 115.7 72.8 86.7 26.4 53.1 69.9 103.3 63.4 39.1 87.5 58.0 87.6 59.8 49.6 65.0 100.8 58.3 165.6 79.0 126.2 52.0 76.4 119.7 115.1 108.5 64.5 93.6 66.8 65.6 63.7 74.5 88.3 71.2 45.8 61.5 103.5 77.3 95.3 79.1 107.3 156.1 26.5 27.6 28.5 29.9 29.2 29.4 31.0 29.5 30.4 28.3 28.8 30.4 59.1 54.5 72.9 19.9 45.3 50.6 59.9 178.0 24.5 40.6 43.0 39.9 108.1 57.2 121.4 46.0 39.6 49.5 52.7 58.6 46.9 100.6 360.7 61.6 50.2 59.2 21.1 240.2 25.4 119.9 51.8 51.1 38.7 64.0 34.1 36.5 46.1 105.0 97.8 23.5 21.1 40.2 109.9 51.0 66.6 109.3 50.4 101.7 58.7 9.4 97.5 65.2 57.7 21.1 17.8 107.4 71.3 37.6 55.6 58.7 92.6 76.9 99.1 63.5 59.2 44.7 60.7 199.7 63.0 49.6 60.7 85.8 52.7 60.6 52.0 80.2 EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" 76.1 68.1 83.8 48.8 86.5 58.7 68.4 90.3 103.7 69.3 92.0 69.1 55.1 67.0 102.9 78.3 67.8 52.3 86.4 87.6 88.8 67.9 91.3 57.3 55.4 87.2 85.2 66.2 90.7 83.0 60.3 59.2 88.4 62.3 58.2 65.4 79.0 63.7 214.4 63.9 57.1 58.8 86.9 49.1 69.8 49.4 85.7 58.1 60.6 136.7 54.2 59.2 71.4 95.2 123.1 248.2 103.9 135.1 133.2 119.6 95.0 137.7 156.9 166.0 143.4 162.0 106.1 48.5 177.7 160.0 145.6 229.4 107.0 135.3 118.7 148.3 103.7 91.9 219.4 154.8 161.0 139.8 87.8 121.4 126.3 121.4 136.0 118.1 139.8 144.6 117.0 186.6 147.1 137.9 109.9 149.9 116.9 165.0 163.5 102.0 94.7 138.3 161.0 186.9 137.1 166.4 101.7 148.3 77.6 74.8 99.3 164.7 106.5 151.3 103.8 131.8 142.7 162.8 251.5 122.0 184.5 164.1 131.1 256.5 158.6 176.9 154.5 173.9 170.0 237.2 170.6 185.8 162.6 187.7 172.2 168.8 88.5 197.8 200.2 166.6 216.1 277.6 83.8 86.5 90.3 103.7 87.6 88.8 87.2 85.2 88.4 86.9 85.7 95.2 75.3 54.5 67.7 8.8 67.9 91.5 103.7 206.5 55.8 35.8 83.7 104.1 58.7 58.6 132.4 66.2 18.8 150.6 62.5 39.5 125.2 180.3 121.8 67.6 55.1 86.1 52.0 38.7 14.1 172.3 173.6 87.8 36.7 69.1 88.0 63.2 64.2 78.6 113.7 18.5 15.4 62.8 166.8 48.5 73.2 27.4 100.6 56.5 101.4 13.1 87.9 98.4 76.2 15.1 16.9 184.0 65.4 90.7 117.9 89.6 71.8 117.5 133.3 42.8 85.5 81.4 123.2 169.7 91.9 60.2 110.0 141.7 68.8 69.7 66.4 125.4 EMC6 "MGC2963, RAB5IFL, TMEM93" ENSG00000127774 "ER membrane protein complex subunit 6" Q9BV81 17 3668812-3669668 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062681 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome Nucleoplasm "HPA062681: AB_2684831" "unprognostic (2.21e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.21e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.86e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (7.58e-3)" "unprognostic (4.17e-2)" "unprognostic (1.94e-1)" "unprognostic (6.37e-2)" "unprognostic (3.27e-1)" "unprognostic (6.32e-2)" 35.6 58.2 35.1 14.7 36.0 30.3 31.4 38.9 40.2 24.7 40.1 40.8 20.0 29.1 11.3 49.3 27.0 5.2 91.0 34.8 37.2 53.2 75.8 29.2 13.3 36.2 35.3 23.4 44.3 18.5 27.7 13.5 35.9 33.0 10.3 17.2 35.5 10.6 185.0 36.9 35.3 9.0 38.5 37.8 47.4 63.3 37.3 15.5 29.6 60.7 12.6 32.8 30.4 37.8 92.8 88.6 38.1 40.1 26.9 21.4 73.2 64.7 31.4 51.7 47.5 54.1 33.8 57.6 91.6 30.3 45.9 87.2 44.5 45.6 37.2 56.0 166.2 41.9 65.4 76.2 38.7 29.3 41.6 27.1 50.6 47.8 33.2 40.9 39.8 68.0 53.4 40.6 38.6 56.2 60.5 86.2 55.0 55.9 99.1 55.7 35.5 55.3 74.2 25.9 31.3 56.7 53.1 41.2 75.6 37.8 48.0 31.1 44.2 43.3 54.4 65.9 96.5 39.5 47.1 38.4 67.7 38.0 53.3 91.6 83.1 87.1 66.1 83.8 61.1 74.6 73.6 73.4 72.7 72.0 75.2 68.5 62.8 56.5 60.7 114.3 92.5 87.4 35.1 36.0 38.9 40.2 34.8 37.2 36.2 35.3 35.9 38.5 37.3 37.8 40.1 16.0 25.9 9.4 60.3 89.0 127.1 144.2 42.1 41.8 82.9 87.8 0.2 82.9 74.8 58.8 35.5 118.4 68.1 55.7 166.3 126.2 252.2 90.0 42.7 56.6 51.4 46.7 7.4 142.8 148.6 40.8 48.4 58.0 55.2 59.8 47.5 148.7 102.5 33.7 8.4 74.7 105.8 57.1 49.6 176.1 38.5 56.6 67.6 3.7 83.3 125.9 77.2 5.5 17.9 164.8 71.6 34.3 81.9 179.9 84.6 203.8 82.2 52.9 39.5 43.3 111.7 151.0 91.6 81.1 101.9 129.0 52.7 65.0 72.6 169.5 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95877266 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Kupffer cells: 110.4;Langerhans cells: 161.3;Microglial cells: 217.4;monocytes: 112.2;Plasma cells: 80.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 102.2" "Group enriched" "Detected in all" 4 "dendritic cells: 31.9;granulocytes: 102.2;monocytes: 41.0" "Group enriched" "Detected in many" 7 "HDLM-2: 147.5;Karpas-707: 135.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002494, HPA014067, CAB079986" Enhanced Uncertain Microtubules NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Microtubules "CAB002494: AB_563557, CAB079986: , HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favorable (7.89e-4)" "unprognostic (5.09e-2)" 11.8 8.3 5.9 24.7 5.5 27.5 10.8 5.0 6.3 17.5 5.0 14.3 9.3 28.0 19.3 19.2 14.0 27.7 8.5 5.3 6.3 7.6 5.4 16.1 20.2 7.1 6.5 5.5 2.8 3.4 3.9 11.4 7.7 11.2 12.8 6.8 6.0 18.1 4.0 6.3 11.7 49.7 6.2 21.5 7.3 4.5 7.5 6.8 20.0 8.7 25.6 30.6 11.0 6.3 1.4 2.7 5.4 7.1 0.1 0.1 5.0 4.5 1.2 0.0 0.0 4.0 1.6 8.2 3.1 0.0 5.3 2.2 0.0 0.0 0.0 147.5 5.2 7.2 4.0 4.3 0.0 12.5 4.1 0.1 0.0 0.6 0.0 2.4 18.2 2.0 5.3 135.4 0.1 4.4 4.7 5.8 5.9 3.6 2.8 15.3 2.4 4.4 1.7 2.2 5.1 6.2 3.6 3.7 3.9 3.6 5.5 5.9 3.9 3.9 2.8 3.8 5.3 21.6 7.2 0.6 4.3 13.9 2.7 0.7 41.0 102.2 0.6 27.2 1.1 13.7 1.6 1.1 31.9 11.4 0.6 0.6 49.4 1.5 6.7 2.1 13.1 15.5 5.9 5.5 5.0 6.3 5.3 6.3 7.1 6.5 7.7 6.2 7.5 6.3 19.6 0.0 1.1 74.1 40.9 8.9 0.3 0.0 0.6 1.4 0.8 1.5 10.1 0.0 0.7 1.8 2.1 0.6 3.7 0.3 1.9 0.0 10.3 0.6 3.6 60.6 0.0 4.4 2.8 2.0 1.9 15.7 6.1 0.6 3.8 0.3 31.4 0.8 26.6 0.0 5.2 0.1 0.0 110.4 161.3 7.3 0.6 62.1 16.0 217.4 112.2 0.4 0.0 20.6 5.0 0.2 1.2 3.0 80.1 0.5 0.1 0.3 0.8 0.8 6.6 1.0 22.7 10.1 4.4 0.8 11.2 15.7 26.9 15.1 1.0 0.5 ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387184-40428744 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.8;cervix: 21.3;salivary gland: 22.4" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 92.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 7 "dendritic cells: 3.5" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;HBEC3-KT: 13.0;hTCEpi: 8.4;RT4: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (2.75e-2)" "unprognostic (9.84e-3)" "unprognostic (2.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (8.40e-2)" "unprognostic (9.88e-3)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (3.25e-1)" "unprognostic (6.53e-2)" "unprognostic (5.99e-2)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" 4.2 1.3 3.4 1.1 20.8 0.1 2.4 2.0 6.5 21.3 0.8 3.5 1.3 3.1 2.4 6.5 0.9 2.0 0.6 4.5 4.5 2.6 0.1 3.9 0.4 6.2 4.0 1.7 15.8 0.5 2.9 0.5 6.1 3.4 2.8 2.6 22.4 4.0 1.2 2.9 1.4 1.9 2.2 4.2 6.8 0.5 5.3 0.9 5.5 2.5 1.7 13.0 3.6 4.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 3.6 0.0 13.0 0.3 0.4 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.2 1.0 0.0 0.0 0.0 1.5 18.4 1.8 0.2 0.4 1.1 0.2 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.4 0.0 3.5 0.2 0.0 3.4 20.8 2.0 6.5 4.5 4.5 6.2 4.0 6.1 2.2 5.3 4.7 5.5 3.2 4.2 4.9 0.2 2.3 1.3 2.3 8.0 0.7 6.1 0.3 0.5 0.0 5.1 0.0 0.0 0.0 1.3 1.0 0.0 2.7 0.4 7.6 2.5 0.7 2.4 0.0 22.6 22.5 0.0 0.4 2.6 14.9 0.0 0.0 0.0 0.0 0.1 0.0 92.6 0.1 0.0 0.0 0.8 0.0 0.3 0.3 0.0 1.9 0.0 3.7 0.0 7.1 5.9 6.9 0.0 0.7 0.1 1.4 0.0 0.0 1.9 0.8 19.7 0.6 19.9 0.2 0.1 14.5 2.3 0.0 0.2 0.1 0.2 4.7 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 8.6 24.2 10.5 30.5 14.8 11.1 16.2 17.0 8.1 19.8 18.1 16.8 17.3 12.6 13.7 14.6 21.2 10.8 12.3 12.2 13.7 20.0 29.3 13.1 9.2 13.5 21.4 27.2 18.3 17.2 12.8 16.8 20.3 32.7 22.0 13.4 15.2 12.4 26.2 16.5 7.6 25.4 20.3 19.9 12.5 14.5 14.7 15.9 29.8 16.7 16.6 11.6 20.8 28.7 34.0 23.5 29.0 36.8 35.0 33.1 30.4 21.3 33.2 40.3 26.4 35.5 22.9 32.8 32.9 24.5 15.8 29.0 40.3 8.6 11.5 18.4 18.1 14.2 23.7 9.8 34.8 22.8 34.7 28.4 29.9 51.9 31.2 26.7 13.2 30.6 36.4 9.3 14.8 11.9 20.1 26.2 10.2 14.3 34.6 10.8 27.0 24.1 27.2 26.6 12.0 17.0 23.7 67.0 12.9 13.6 38.6 39.1 38.3 43.7 24.1 24.7 11.5 45.5 51.3 11.5 39.4 17.0 5.7 13.4 7.4 8.6 8.8 8.7 7.3 8.1 7.5 6.5 9.2 7.3 14.4 4.8 7.0 6.8 6.3 6.9 8.6 10.5 11.1 16.2 10.8 12.3 13.1 9.2 12.8 7.6 12.5 11.6 15.9 19.2 34.5 10.7 25.8 6.5 12.0 17.6 8.6 32.1 11.4 8.6 24.6 7.2 27.3 14.7 14.6 16.1 33.4 25.1 0.0 15.6 8.6 13.6 21.6 15.8 17.3 10.3 31.4 16.9 16.9 16.9 23.9 23.9 17.7 18.9 12.1 11.5 12.3 47.1 37.4 19.7 20.3 14.2 15.5 19.2 7.2 18.2 12.4 19.7 19.4 15.2 18.6 23.1 23.1 21.8 13.3 8.6 46.9 18.9 18.8 5.0 15.0 35.9 13.1 14.3 14.6 21.5 22.8 9.5 5.5 20.2 21.3 11.7 12.4 18.9 ENTPD7 "FLJ30978, LALP1" ENSG00000198018 "Ectonucleoside triphosphate diphosphohydrolase 7" Q9NQZ7 10 99659509-99711241 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 17.5;Urothelial cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014351 Uncertain Approved Nucleoplasm NA NA 65000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA014351: AB_1848183" "unprognostic (1.82e-1)" "unprognostic (7.26e-2)" "unprognostic (1.11e-2)" "unprognostic (6.01e-3)" "unprognostic (6.22e-2)" "unprognostic (3.32e-3)" "unprognostic (9.35e-2)" "unprognostic (3.77e-3)" "unprognostic (3.83e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "unprognostic (1.22e-1)" "unprognostic (2.99e-2)" "unprognostic (3.39e-1)" 1.8 3.7 0.4 4.2 0.5 7.0 2.2 1.7 0.7 3.2 3.9 3.7 14.6 2.1 2.2 4.4 1.8 4.5 1.3 0.7 0.2 2.7 6.3 1.9 2.2 0.3 0.4 1.0 6.9 2.9 1.7 6.5 0.2 2.7 3.8 2.7 2.9 2.3 0.5 2.9 14.6 2.7 0.3 2.1 3.9 1.4 0.3 1.6 2.2 0.4 2.7 10.2 2.6 0.5 5.4 5.9 8.0 14.4 4.0 3.6 8.4 10.0 19.1 11.4 9.2 11.1 5.2 4.8 5.4 14.0 3.6 13.6 6.0 4.0 9.6 2.3 5.6 4.0 4.4 11.2 5.8 13.4 7.8 3.5 6.7 14.1 15.3 14.1 11.8 5.1 6.1 4.7 4.8 4.6 2.6 3.9 4.7 6.0 2.4 0.3 6.2 2.4 15.8 16.7 3.4 6.9 6.7 2.7 9.5 5.4 7.1 5.9 8.5 11.0 6.2 7.0 8.4 4.7 7.3 4.1 11.0 4.4 2.7 0.3 0.6 0.9 0.6 0.7 0.5 0.2 0.3 0.5 1.3 0.1 0.4 0.3 0.5 0.8 0.4 2.3 0.2 0.3 0.4 0.5 1.7 0.7 0.7 0.2 0.3 0.4 0.2 0.3 0.3 0.5 1.2 0.0 0.0 2.9 1.3 8.2 17.5 4.6 10.8 0.7 2.0 1.1 0.8 1.5 2.2 5.5 2.1 6.3 3.2 3.7 0.0 2.3 1.5 6.0 2.8 1.7 5.4 1.3 9.5 5.0 5.3 2.4 9.2 5.3 0.0 0.7 0.7 4.7 1.9 0.0 7.9 4.2 0.0 0.6 2.7 2.7 0.9 2.6 0.0 6.5 4.9 0.4 0.0 10.1 3.2 4.5 3.1 0.7 7.6 2.6 11.4 1.3 3.6 1.9 0.0 1.1 1.7 1.2 0.8 6.9 7.4 5.1 1.2 3.9 2.4 23.6 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Gastric mucus-secreting cells: 13.3;Proximal enterocytes: 13.2;Squamous epithelial cells: 28.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "CACO-2: 17.9;HaCaT: 16.6;HBEC3-KT: 13.5;MCF7: 15.0;NTERA-2: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.1 0.0 0.0 1.3 0.0 0.3 2.2 0.4 0.1 11.2 1.2 3.7 8.4 0.3 1.2 57.2 3.4 1.5 0.0 0.0 0.0 5.8 15.6 2.3 2.0 0.0 0.0 0.0 5.7 206.5 2.5 0.6 0.0 4.0 1.6 0.0 11.0 1.2 0.0 19.7 6.2 0.1 0.0 0.9 4.2 1.9 0.0 3.4 5.4 0.0 3.5 1.9 25.8 0.1 8.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 17.9 7.1 0.0 0.1 0.0 0.0 16.6 0.0 13.5 0.0 0.0 0.0 1.8 0.0 1.7 0.0 0.8 0.1 0.0 4.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 15.0 0.0 1.9 54.4 8.8 0.0 0.0 0.0 0.0 1.1 6.7 0.3 0.0 0.0 8.2 0.0 3.2 3.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.2 0.0 3.8 2.9 0.1 0.1 0.0 0.4 0.1 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.2 0.3 0.1 2.0 6.3 6.5 6.8 0.0 3.3 5.0 1.0 2.8 9.9 7.3 0.0 2.0 0.2 4.2 0.0 4.4 23.3 4.0 1.0 0.2 1.2 0.0 0.6 4.3 2.6 0.5 13.3 6.6 0.0 0.0 0.4 8.8 0.4 0.0 0.3 4.7 2.0 0.3 0.3 9.9 0.6 0.3 0.0 1.0 0.0 0.3 0.0 0.5 0.2 6.3 8.8 0.0 0.6 2.0 13.2 1.5 2.1 0.2 0.0 0.4 0.4 0.5 1.9 28.7 3.7 1.0 4.4 0.0 7.6 5.5 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Metabolic proteins, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 21.3" "Group enriched" "Detected in some" 10 "Excitatory neurons: 202.5;Inhibitory neurons: 162.8;Oligodendrocyte precursor cells: 96.0" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.5" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 10.0;PC-3: 9.4;TIME: 12.6;U-138 MG: 25.5;U-2197: 15.7;U-251 MG: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 33000 "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.0 0.8 3.3 0.1 5.3 0.0 0.0 0.0 21.3 2.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.8 16.2 2.4 0.0 0.0 0.1 0.0 2.6 1.4 2.3 0.0 0.0 0.7 0.9 4.0 1.5 0.1 1.5 0.3 1.4 0.0 0.2 0.0 0.2 1.8 0.3 0.3 0.7 0.3 0.0 0.9 0.0 0.0 0.1 0.5 3.1 0.0 0.7 0.8 0.0 0.8 0.4 0.0 0.4 1.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 4.4 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 0.3 0.0 0.0 1.5 2.6 0.0 0.0 0.0 0.1 0.0 9.4 0.0 2.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 12.6 25.5 3.1 15.7 20.6 0.0 0.0 0.0 2.6 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.3 0.0 21.3 16.2 2.4 2.6 1.4 4.0 1.8 0.3 3.1 0.0 0.0 0.0 8.5 0.0 0.5 0.0 0.0 0.0 2.7 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 2.2 0.1 0.0 0.0 202.5 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.7 162.8 0.0 0.0 0.0 0.0 15.2 0.9 0.0 3.6 5.6 0.0 5.7 0.0 96.0 4.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.7 0.4 0.0 0.1 0.0 0.0 0.7 0.0 0.1 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 27.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.2;Cone photoreceptor cells: 2.1;Early spermatids: 2.8;Horizontal cells: 3.3;Late spermatids: 5.8;Rod photoreceptor cells: 8.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 59.6" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 4 "cerebellum: 11.7" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.0 3.5 2.7 0.0 2.3 0.0 0.0 1.5 2.3 0.0 27.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 0.0 0.0 0.0 0.0 1.9 3.1 0.0 3.3 0.0 1.5 0.0 2.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 2.3 4.6 0.0 2.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.6 4.8 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 1.5 2.3 4.9 5.3 1.9 3.1 2.0 2.3 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 66.0;skin 1: 65.8" "Cell type enhanced" "Detected in many" "Muller glia cells: 226.6;Sertoli cells: 105.2;Suprabasal keratinocytes: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "MOLT-4: 39.6;RT4: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035784 Uncertain "Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "Nuclear speckles" "HPA035784: AB_2674781" "unprognostic (1.90e-2)" "prognostic favorable (1.80e-4)" "unprognostic (7.08e-3)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (2.53e-3)" "unprognostic (3.15e-2)" "unprognostic (4.39e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.06e-3)" "unprognostic (3.18e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.16e-1)" "prognostic favorable (4.68e-5)" 9.2 0.7 26.9 1.8 42.0 2.2 3.6 9.7 66.0 18.6 9.2 2.6 0.0 8.9 2.3 10.6 13.5 1.5 3.2 27.7 14.4 4.0 1.5 4.0 2.3 12.9 14.1 7.9 12.4 0.9 2.4 0.4 12.9 14.3 0.1 2.8 5.7 7.3 1.4 65.8 5.0 1.6 12.6 4.3 3.3 5.0 16.7 14.5 9.4 0.7 2.3 7.8 18.5 48.7 0.2 0.0 0.0 0.8 7.5 3.0 0.0 0.9 0.8 0.2 0.1 1.0 2.3 0.0 0.0 0.1 0.0 8.8 0.4 0.0 0.0 2.0 0.3 0.6 0.0 0.3 1.2 9.7 0.4 1.7 0.8 3.0 0.0 0.1 0.5 5.2 2.1 0.0 0.1 0.2 39.6 5.8 6.8 1.4 3.6 0.8 0.0 0.0 0.0 71.7 0.0 0.0 3.3 2.0 0.0 1.5 6.1 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.6 0.0 0.0 3.5 0.0 0.0 0.8 0.4 0.0 0.3 0.3 1.6 1.1 0.6 0.5 0.3 1.4 0.7 0.5 0.0 0.1 0.0 1.0 0.7 26.9 42.0 9.7 66.0 27.7 14.4 12.9 14.1 12.9 12.6 16.7 48.7 1.9 3.2 1.7 6.2 12.5 54.4 30.7 13.3 42.1 12.1 1.8 6.7 3.0 45.8 10.0 7.3 2.1 0.2 1.9 0.1 5.9 28.2 0.9 5.7 20.0 2.8 1.8 8.6 65.1 6.8 0.0 15.6 6.1 7.2 0.0 3.2 1.8 3.5 4.2 0.0 43.4 0.1 0.0 13.2 10.4 8.3 30.1 8.9 12.4 8.4 7.1 226.6 5.2 5.5 4.6 32.4 0.1 9.8 1.6 11.0 0.0 0.6 4.9 6.6 105.2 31.5 20.5 0.5 7.2 40.0 118.5 0.3 14.0 0.7 0.1 22.2 EPSTI1 "BRESI1, MGC29634" ENSG00000133106 "Epithelial stromal interaction 1" Q96J88 13 42886388-42992271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 168.1;monocytes: 144.2;Proximal enterocytes: 156.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 95.8;BJ hTERT+ SV40 Large T+ RasG12V: 99.6;HDLM-2: 74.2;RPMI-8226: 35.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017362 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "HPA017362: AB_1848226" "unprognostic (2.06e-1)" "unprognostic (3.51e-1)" "unprognostic (1.80e-1)" "unprognostic (3.59e-2)" "unprognostic (2.35e-1)" "unprognostic (9.55e-2)" "unprognostic (2.31e-1)" "unprognostic (2.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.90e-2)" "unprognostic (3.91e-2)" "unprognostic (1.05e-3)" "unprognostic (8.13e-2)" 7.5 7.7 3.7 31.6 4.1 33.6 4.8 3.1 5.1 5.7 2.8 12.6 33.7 6.0 1.6 5.0 3.7 18.1 4.7 3.1 3.6 8.0 12.9 16.8 34.2 7.8 4.6 3.1 3.5 7.6 2.7 16.8 5.2 2.7 11.0 0.3 18.5 4.8 2.2 1.5 32.0 9.7 5.5 31.3 15.8 7.4 4.4 27.7 3.1 2.5 20.7 13.1 3.6 4.5 2.8 0.1 0.0 0.0 0.1 5.2 3.0 2.3 26.0 95.8 99.6 23.2 5.7 3.7 0.8 3.4 10.1 11.4 0.2 3.9 12.2 74.2 0.2 11.9 0.0 0.1 22.9 0.0 2.0 17.4 5.2 7.7 0.5 1.4 1.4 5.7 0.0 17.9 2.5 0.2 19.0 2.9 0.5 1.9 0.1 0.2 0.1 35.7 16.1 0.7 2.0 0.0 0.3 0.0 1.9 0.4 0.6 1.9 3.9 0.0 0.0 1.0 0.0 0.8 0.6 0.0 1.9 0.0 1.0 52.3 34.4 29.4 10.8 59.3 11.4 26.7 22.3 12.3 31.1 23.7 10.4 7.8 16.1 24.4 39.3 3.8 59.0 22.5 3.7 4.1 3.1 5.1 3.1 3.6 7.8 4.6 5.2 5.5 4.4 4.5 26.5 19.2 10.9 1.3 40.0 4.2 1.7 4.1 0.6 0.0 1.2 1.8 2.9 12.8 9.2 5.5 0.0 10.9 27.1 26.5 1.9 40.9 89.0 10.2 18.8 18.8 24.6 31.5 0.3 39.0 168.1 15.9 15.3 20.7 10.8 22.4 12.5 6.3 84.2 0.0 11.6 25.1 2.0 39.2 28.3 27.1 14.9 68.7 10.6 84.3 144.2 0.2 37.0 4.5 0.3 51.2 55.4 4.9 23.6 3.6 156.0 39.1 6.5 0.1 0.0 2.6 10.6 2.6 1.7 2.8 3.8 14.5 37.0 43.9 37.6 3.7 ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 247.8;Intestinal goblet cells: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" 67.3 147.8 33.4 49.1 31.2 44.9 60.3 47.4 35.4 127.2 26.7 97.7 79.5 67.4 75.3 55.0 72.4 50.2 60.9 35.8 31.8 66.1 193.2 77.8 40.8 41.4 36.4 56.9 80.6 50.7 48.5 47.9 38.1 146.8 102.7 21.6 97.6 69.8 92.3 46.7 79.4 64.1 33.0 69.2 107.1 25.3 41.3 83.1 75.2 91.9 55.0 58.3 54.3 34.0 120.2 112.8 95.0 211.6 353.3 262.0 51.9 239.5 179.3 105.5 97.4 159.5 120.4 114.8 166.9 406.4 181.7 43.2 68.5 316.8 123.3 92.0 67.5 70.7 156.1 86.1 258.9 33.3 21.6 223.8 128.6 155.8 143.8 173.8 171.0 117.8 42.6 156.8 177.1 150.4 96.5 57.6 56.0 283.7 101.4 327.4 62.9 358.5 245.2 68.6 52.9 96.0 82.7 234.7 120.6 91.1 98.0 37.4 132.4 171.3 69.1 165.9 99.2 246.8 294.0 47.5 236.9 78.3 76.2 3.7 7.5 19.2 3.1 10.5 5.2 9.3 1.6 2.1 6.1 6.2 1.0 2.3 30.6 14.3 14.3 3.1 1.0 5.1 33.4 31.2 47.4 35.4 35.8 31.8 41.4 36.4 38.1 33.0 41.3 34.0 41.9 57.7 29.5 22.9 62.0 22.8 32.1 22.7 14.8 37.2 51.2 35.1 32.9 68.6 29.4 49.7 16.7 20.7 44.3 83.6 21.5 101.9 11.5 36.2 48.0 33.5 26.0 25.9 35.4 60.8 90.3 47.2 49.5 77.9 23.5 64.4 37.5 247.8 41.1 21.9 41.8 202.9 36.7 77.0 105.2 33.8 65.0 54.8 7.2 30.0 91.1 39.0 36.0 47.7 30.6 86.9 59.3 58.3 96.2 74.2 95.0 38.5 28.4 12.6 39.5 56.1 41.1 1.9 10.5 27.2 26.9 9.0 25.1 103.5 73.3 47.8 ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" 38.5 32.5 22.7 37.8 24.6 10.5 46.0 25.1 29.0 34.4 20.8 37.1 34.4 34.4 50.1 46.0 24.2 33.1 52.4 22.6 25.9 30.6 47.6 26.3 33.8 24.9 23.9 26.9 40.2 47.2 20.7 53.1 24.3 39.5 33.7 29.4 49.2 34.5 33.8 19.2 34.9 39.3 25.4 26.7 32.6 57.8 24.4 35.0 45.1 47.0 43.6 50.1 22.1 34.4 96.7 87.0 69.1 46.8 94.8 111.5 170.1 153.1 123.4 92.7 98.3 115.7 157.6 51.3 149.1 120.7 168.7 98.7 66.0 98.3 146.4 112.6 69.4 84.0 114.6 68.3 55.7 121.2 70.0 79.1 75.9 115.8 116.7 169.3 71.8 69.8 70.5 144.6 122.6 52.3 60.3 126.2 98.9 101.3 235.0 54.9 189.9 107.6 75.5 140.1 26.5 43.2 77.2 86.5 91.5 145.9 168.0 96.7 81.8 124.1 108.1 169.1 167.6 106.4 145.5 106.0 103.7 87.3 105.3 92.3 50.2 70.6 84.7 79.9 102.9 83.2 107.6 101.2 55.1 71.0 106.6 90.3 181.1 72.1 101.1 120.9 130.8 90.1 22.7 24.6 25.1 29.0 22.6 25.9 24.9 23.9 24.3 25.4 24.4 34.4 54.6 28.9 28.6 20.9 74.3 57.9 68.9 144.1 39.9 54.8 57.2 55.1 61.7 38.6 99.0 53.3 54.2 119.2 60.8 19.4 49.0 72.7 383.0 48.7 66.5 43.7 41.8 44.8 39.2 62.8 120.6 73.0 25.5 54.6 55.8 44.2 34.6 50.2 56.4 48.8 37.8 33.5 87.5 25.5 40.2 51.9 52.5 37.1 62.2 14.0 41.6 69.5 52.5 32.2 48.3 58.1 20.5 59.8 154.0 85.7 32.4 49.5 64.6 60.0 32.9 58.5 105.7 75.0 36.3 49.4 66.3 156.2 68.0 54.0 34.7 78.8 ERGIC3 "C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84" ENSG00000125991 "ERGIC and golgi 3" Q9Y282 20 35542038-35557634 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 711.0;Late spermatids: 708.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015242, HPA015968" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA015242: AB_1848238, HPA015968: AB_1848239" "unprognostic (4.36e-2)" "unprognostic (3.43e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (2.20e-7)" "unprognostic (2.61e-1)" "unprognostic (2.90e-2)" "unprognostic (9.59e-2)" "unprognostic (8.59e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (9.81e-5)" "unprognostic (9.53e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (8.64e-2)" 123.3 167.5 123.4 77.7 124.6 164.5 174.9 124.4 180.6 161.8 183.3 154.6 124.2 127.4 456.9 146.9 325.4 135.1 123.8 123.8 131.5 145.3 181.0 115.1 99.4 128.2 129.9 188.3 270.3 188.0 86.9 151.3 128.2 125.9 190.9 67.0 196.9 142.3 103.5 151.4 110.4 142.6 124.7 108.3 162.0 211.6 133.9 119.9 199.8 95.2 154.6 154.0 137.5 128.2 173.2 317.5 161.8 282.4 553.6 417.1 210.1 234.4 503.7 378.3 374.0 726.9 354.2 127.4 214.4 495.4 332.8 249.5 137.7 371.9 279.0 62.8 252.5 272.6 221.1 453.2 285.2 240.1 193.2 462.8 578.1 235.1 298.7 432.5 251.1 163.0 189.8 399.3 307.0 379.1 191.4 354.0 93.4 645.1 305.1 143.1 378.8 365.5 315.6 298.7 155.4 225.5 353.4 286.0 284.7 159.8 276.5 389.0 209.8 429.5 169.0 178.0 208.1 164.7 107.0 102.5 461.2 126.4 235.5 98.5 188.7 106.7 117.9 182.2 143.3 157.9 139.2 130.4 228.7 146.6 136.0 139.9 62.0 150.7 158.9 226.6 177.0 237.8 123.4 124.6 124.4 180.6 123.8 131.5 128.2 129.9 128.2 124.7 133.9 128.2 48.1 35.3 79.9 14.4 107.1 184.2 209.7 289.4 150.2 27.1 194.3 150.2 37.1 153.0 190.7 62.5 18.8 476.5 80.6 224.5 117.4 210.6 711.0 215.5 99.4 101.8 112.6 93.2 8.9 269.8 490.7 122.7 114.7 77.5 78.0 94.7 146.3 146.4 208.1 16.8 10.1 246.9 152.5 148.2 192.5 708.4 105.3 100.4 190.3 8.4 126.7 76.8 82.4 8.0 13.6 185.0 283.1 94.0 344.1 189.8 213.4 207.5 340.2 31.3 118.3 100.5 122.0 415.9 170.5 172.6 200.6 589.4 86.8 111.3 264.6 292.3 ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 49.9;Late spermatids: 48.5;Spermatocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041741: AB_10804116" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (2.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.24e-2)" "unprognostic (7.41e-3)" "unprognostic (1.96e-1)" "unprognostic (8.14e-2)" "unprognostic (1.66e-3)" "unprognostic (4.74e-2)" "unprognostic (3.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.31e-2)" 13.8 14.6 5.3 8.4 7.1 10.1 13.1 5.4 6.7 13.7 5.6 11.2 6.3 13.8 20.5 10.5 13.2 7.7 6.8 5.3 5.9 16.1 18.6 9.7 13.8 6.9 6.1 17.4 11.4 6.9 15.4 7.4 7.2 12.7 7.4 14.6 11.0 8.6 14.9 18.7 13.6 6.4 6.5 17.3 10.9 22.1 6.1 9.9 13.2 2.5 13.6 11.2 10.8 9.1 5.1 7.5 9.7 14.8 6.9 11.4 5.1 5.3 7.7 5.0 6.3 2.0 8.3 8.0 4.8 6.5 6.1 13.3 4.0 10.3 4.4 8.6 4.4 11.5 9.9 3.0 13.7 16.1 7.6 13.4 10.4 6.1 15.5 12.8 3.4 14.0 8.0 11.4 6.5 7.7 6.8 14.4 3.2 5.7 5.4 7.5 6.0 13.0 6.2 4.0 3.8 7.0 9.0 9.0 4.9 6.3 7.1 12.8 5.3 5.7 3.4 9.1 6.5 13.1 17.5 6.7 7.2 9.7 6.6 1.6 4.2 1.8 5.2 7.9 5.2 5.1 6.0 5.9 4.4 6.0 4.7 4.4 0.4 5.2 9.7 3.7 7.6 3.9 5.3 7.1 5.4 6.7 5.3 5.9 6.9 6.1 7.2 6.5 6.1 9.1 8.5 3.2 11.1 20.2 6.2 4.1 4.4 7.7 5.2 12.0 5.9 5.1 2.8 5.7 7.7 5.5 10.4 12.2 4.7 3.0 11.7 9.8 49.9 10.8 9.4 5.0 6.0 4.6 9.3 8.5 8.3 7.0 5.6 6.9 2.5 11.7 7.9 10.1 5.9 5.0 11.8 2.9 6.1 5.7 4.4 48.5 4.4 6.1 3.6 8.4 5.6 14.6 5.2 17.1 20.7 5.3 2.4 4.5 4.4 2.5 5.7 9.5 15.5 10.8 6.6 5.5 5.8 37.8 18.0 5.5 3.1 7.1 4.7 10.3 3.4 3.4 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 53.0;pancreas: 66.7" "Cell type enhanced" "Detected in many" "Plasma cells: 325.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cell line enhanced" "Detected in many" "Karpas-707: 74.6;RPMI-8226: 40.2;U-266/70: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 9.5 53.0 1.5 5.4 1.7 13.4 7.5 2.6 3.2 22.6 2.1 7.7 6.3 10.1 6.4 9.5 14.3 6.2 6.1 1.6 2.4 5.6 23.5 16.5 5.8 1.7 1.0 16.9 66.7 4.3 19.5 5.6 1.3 9.9 4.5 8.8 15.7 7.1 6.8 11.3 10.6 5.6 1.0 15.8 16.2 2.8 1.6 6.8 10.2 2.4 6.6 8.3 11.7 1.7 4.0 4.0 2.2 4.8 4.8 4.4 9.8 4.1 9.7 2.8 1.3 2.5 2.3 6.6 3.2 2.8 3.5 3.6 1.9 4.5 6.1 1.6 1.5 6.0 3.2 2.4 19.6 3.2 2.1 3.8 8.1 6.4 21.5 3.5 5.0 4.7 4.2 74.6 2.8 3.9 4.5 1.0 0.6 3.6 3.2 4.2 4.2 40.2 1.1 5.5 7.1 3.5 4.3 6.1 5.7 3.5 3.8 5.9 5.9 2.5 4.1 6.4 2.7 77.4 23.9 4.8 4.0 2.1 4.2 17.9 0.9 0.4 4.9 0.4 9.0 0.2 3.3 4.1 0.4 0.3 0.9 0.9 4.9 2.5 0.3 7.7 0.8 1.0 1.5 1.7 2.6 3.2 1.6 2.4 1.7 1.0 1.3 1.0 1.6 1.7 31.9 0.0 36.1 7.2 27.8 22.0 54.3 8.3 15.4 4.0 35.0 29.7 8.6 11.5 8.6 12.9 6.2 8.1 106.4 10.0 1.9 12.6 2.3 26.1 49.1 18.3 79.7 11.2 8.6 27.3 8.8 42.2 52.0 79.4 8.2 11.8 13.9 26.8 8.0 3.3 6.1 8.2 8.2 15.7 71.3 1.7 4.7 60.4 74.7 12.2 10.2 3.5 28.8 6.0 4.6 17.9 7.3 6.0 325.8 44.7 7.9 4.4 6.1 26.5 0.0 19.0 25.7 4.0 4.1 27.7 45.0 54.9 88.2 12.0 9.6 60.1 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 ERVV-2 ENVV2 ENSG00000268964 "Endogenous retrovirus group V member 2, envelope" B6SEH9 19 53044740-53051680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "placenta: 8.4" "Cell type enriched" "Detected in single" 4 "Syncytiotrophoblasts: 3.8" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 16.9;SuSa: 10.9;T-47d: 4.6;U-266/84: 2.8" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Centrosome "HPA076115: " "unprognostic (3.14e-3)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (4.33e-9)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.60e-4)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 10.9 4.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 ERVW-1 "envW, ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW" ENSG00000242950 "Endogenous retrovirus group W member 1, envelope" Q9UQF0 7 92468380-92477986 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 54.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 272.2;Syncytiotrophoblasts: 853.9" "Cancer enriched" "Detected in single" 143 "testis cancer: 31.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "BEWO: 85.2;SuSa: 26.2" "Not detected" "Not detected" NA NA 54000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (2.85e-1)" "unprognostic (1.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (1.48e-4)" "unprognostic (4.80e-1)" "unprognostic (1.01e-1)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-2)" "unprognostic (8.02e-2)" 0.5 0.7 0.6 0.8 1.2 0.7 0.7 1.8 1.1 0.2 0.7 0.4 0.5 0.5 3.4 0.1 0.2 0.3 0.2 0.8 1.5 0.3 0.3 0.6 0.7 1.4 0.5 0.5 0.7 0.3 0.0 54.5 1.6 0.5 0.5 6.9 1.0 0.2 0.6 1.0 0.6 0.4 0.2 0.9 1.2 6.0 1.4 0.4 0.7 0.0 0.4 0.2 0.0 4.0 0.2 0.4 0.7 0.5 0.0 0.6 85.2 0.2 0.0 0.0 0.0 0.4 0.4 0.2 0.5 0.0 1.2 0.6 0.3 0.2 0.1 0.2 0.4 0.4 1.4 0.3 0.1 0.4 0.6 0.2 0.2 0.1 0.0 0.3 0.0 0.6 0.7 1.3 0.1 0.5 0.4 0.7 0.3 0.1 0.2 0.5 0.2 0.1 0.2 0.4 0.3 0.6 0.1 1.2 0.0 26.2 0.3 0.5 0.2 0.1 1.5 0.4 0.2 1.5 0.7 0.2 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 1.2 1.8 1.1 0.8 1.5 1.4 0.5 1.6 0.2 1.4 4.0 0.7 3.2 3.1 0.0 0.1 0.8 0.8 0.2 0.0 2.1 0.1 0.1 0.2 0.0 1.4 0.0 0.0 272.2 0.0 0.1 0.0 0.0 47.9 0.4 0.2 1.4 0.0 0.0 0.1 0.0 86.2 2.4 0.0 0.2 2.5 0.1 0.0 0.0 27.4 0.0 0.1 0.0 0.0 1.9 0.7 10.4 1.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.4 0.1 0.4 0.0 0.1 5.3 1.8 0.0 2.6 0.4 1.0 0.3 0.0 2.0 853.9 0.3 0.1 0.1 1.0 ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" 107.9 39.3 15.2 38.5 14.4 18.7 72.7 18.5 18.9 36.6 19.8 45.9 17.2 53.4 22.2 29.2 47.1 27.8 24.5 13.5 23.0 26.8 46.7 45.0 45.9 34.2 21.7 38.8 39.5 40.7 11.7 38.7 36.2 30.5 36.2 8.9 28.0 47.2 54.2 26.1 30.7 74.4 22.5 37.2 29.3 12.1 23.6 36.6 27.8 33.3 49.8 44.7 32.3 24.0 107.0 78.1 62.2 158.2 90.8 67.3 53.4 117.4 129.3 136.2 94.4 72.4 114.3 40.8 92.2 201.3 50.7 118.7 73.7 120.4 121.6 58.8 54.2 244.7 56.0 58.5 125.9 193.2 371.6 76.7 125.5 147.1 81.3 145.3 117.8 39.2 153.6 263.9 124.4 81.2 70.4 116.4 78.9 44.6 102.5 105.4 85.0 107.3 113.7 89.0 52.4 54.8 174.1 52.9 80.5 71.3 111.1 128.4 154.5 104.8 94.7 59.7 85.7 62.3 99.0 58.7 97.3 79.6 111.7 423.2 37.4 423.0 127.2 69.4 157.2 62.4 129.4 129.5 87.2 48.2 102.3 120.2 9.3 84.2 85.6 29.7 139.6 177.8 15.2 14.4 18.5 18.9 13.5 23.0 34.2 21.7 36.2 22.5 23.6 24.0 44.4 9.6 9.3 4.6 25.9 16.3 19.8 23.5 14.2 5.5 20.5 21.3 8.2 14.3 12.9 31.3 10.4 31.9 22.3 6.1 0.0 36.8 2.0 20.5 15.1 28.2 25.2 17.9 10.2 26.8 18.1 17.6 9.2 19.3 62.7 24.7 27.1 37.8 46.4 0.0 7.1 12.0 22.4 21.3 24.8 2.1 17.4 22.9 35.6 6.5 50.6 5.7 60.8 2.0 4.1 26.2 3.5 25.2 18.5 19.9 2.2 4.4 10.7 5.9 52.6 14.3 22.0 3.9 2.9 18.0 11.9 37.9 40.3 12.5 10.8 12.7 EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" 5.7 8.1 5.9 4.5 8.3 2.7 4.4 8.5 5.8 5.9 8.2 4.8 4.3 6.4 4.6 4.0 5.1 5.8 7.1 4.2 7.7 5.0 16.4 7.1 3.2 8.1 6.2 3.8 3.8 7.9 3.9 12.1 6.8 5.3 5.5 4.9 4.5 5.6 2.9 5.0 4.0 7.1 8.6 4.5 6.4 9.6 6.3 1.3 6.6 3.6 3.3 5.5 3.8 10.9 5.4 5.9 9.1 8.9 14.5 18.2 8.6 12.2 18.5 8.2 9.4 10.4 1.4 2.4 16.8 14.0 15.2 6.1 8.6 9.0 14.6 0.2 3.3 4.3 5.6 6.2 14.2 3.1 4.8 11.5 7.2 14.2 8.5 23.9 17.9 0.2 7.7 3.8 13.9 2.7 0.3 3.6 2.6 3.5 4.8 2.2 21.7 3.2 6.3 15.5 3.4 7.0 14.4 7.4 16.6 9.8 3.6 7.1 11.8 9.1 6.6 12.2 8.1 5.5 3.4 3.8 6.0 5.0 7.6 0.9 2.7 2.8 0.1 1.9 0.0 1.2 0.1 0.0 1.3 1.2 0.0 0.0 3.4 0.1 2.9 0.8 0.0 0.4 5.9 8.3 8.5 5.8 4.2 7.7 8.1 6.2 6.8 8.6 6.3 10.9 27.2 60.9 29.9 91.4 18.7 43.5 29.3 23.0 18.2 24.5 20.5 17.7 51.8 22.8 32.3 16.5 25.0 48.4 7.5 22.9 17.6 27.9 3.0 67.8 39.4 31.2 22.1 11.4 158.4 29.9 26.0 42.5 42.3 26.2 13.3 21.9 43.2 52.4 32.2 30.3 149.3 27.0 14.2 54.0 27.0 5.8 28.3 45.1 26.6 114.3 48.9 28.5 5.2 112.6 199.6 68.4 19.3 54.2 28.8 28.1 21.8 20.1 46.9 25.4 13.1 51.4 56.4 37.4 42.4 21.2 50.0 65.5 5.5 60.9 20.0 32.1 EVI5L ENSG00000142459 "Ecotropic viral integration site 5 like" Q96CN4 19 7830233-7864976 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.5;Horizontal cells: 33.7;Late spermatids: 32.6;Oligodendrocyte precursor cells: 50.3;Oligodendrocytes: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "U-2197: 53.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043099, HPA043563" Approved Approved "Nuclear bodies" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear bodies" "HPA043099: AB_10796685, HPA043563: AB_2678556" "unprognostic (3.90e-2)" "unprognostic (4.69e-2)" "unprognostic (9.29e-3)" "unprognostic (2.18e-2)" "unprognostic (1.74e-1)" "unprognostic (1.34e-2)" "unprognostic (2.06e-3)" "unprognostic (1.90e-2)" "unprognostic (7.66e-2)" "unprognostic (3.00e-1)" "unprognostic (7.48e-3)" "unprognostic (1.97e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (1.37e-2)" "unprognostic (2.04e-2)" 6.8 10.4 29.5 5.0 30.2 3.1 6.6 23.0 35.2 9.4 2.5 13.4 4.9 11.2 4.6 10.6 8.4 5.1 17.1 30.5 27.6 11.6 6.3 7.2 4.2 34.1 28.5 7.3 6.3 8.8 16.4 7.9 29.8 12.1 4.1 11.1 7.5 9.1 20.5 13.7 6.9 8.7 21.3 8.1 9.3 36.1 32.1 6.4 8.6 14.9 4.4 11.1 9.0 41.1 13.5 2.7 10.5 15.4 18.8 15.7 29.5 19.7 20.5 13.8 14.7 1.1 5.0 3.4 23.1 26.9 7.3 9.1 3.8 13.4 12.7 19.6 12.7 2.6 6.3 2.2 23.7 3.1 6.7 14.7 15.9 6.8 31.9 11.4 16.9 17.5 3.1 17.8 14.4 13.8 10.8 6.8 3.9 10.0 28.4 13.0 8.7 10.0 8.3 11.3 4.3 10.3 18.3 8.1 5.8 7.0 6.8 9.9 16.7 9.4 4.4 53.6 7.4 25.7 6.2 4.6 15.9 7.5 8.3 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.1 0.1 1.1 0.1 0.2 0.0 29.5 30.2 23.0 35.2 30.5 27.6 34.1 28.5 29.8 21.3 32.1 41.1 3.6 0.0 5.1 13.1 1.6 3.8 2.2 2.4 2.2 30.5 3.6 3.3 4.0 2.8 1.8 9.2 18.8 3.7 1.6 7.4 0.0 2.4 14.8 2.2 4.3 3.8 5.4 1.3 16.3 2.6 16.9 3.1 6.1 4.2 0.0 5.7 3.6 2.0 3.8 33.7 19.7 4.2 6.1 2.5 1.1 32.6 4.1 2.8 3.6 9.4 1.1 7.1 1.0 50.3 69.8 3.0 3.5 4.5 2.0 2.5 1.7 4.1 1.8 18.8 6.6 2.0 4.0 18.3 7.3 3.6 4.1 3.4 2.2 8.2 3.4 5.1 FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 183.9;stomach 1: 61.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 85.1;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 307.9;Paneth cells: 75.2;Urothelial cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 38.1;HAP1: 48.6;JURKAT: 89.8;OE19: 61.5;SK-BR-3: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" 0.3 0.3 41.7 4.3 89.1 0.3 2.8 77.9 63.0 1.9 11.7 21.2 10.3 0.2 2.2 7.9 1.8 17.8 0.3 46.1 56.1 8.2 0.2 1.4 0.7 129.2 79.6 0.0 8.4 10.1 0.6 0.7 106.0 1.9 19.4 0.4 11.0 0.7 0.0 8.5 14.4 1.1 65.2 0.5 61.1 2.9 75.2 4.7 2.0 0.1 5.9 26.3 2.2 183.9 9.2 38.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.5 0.0 20.8 21.0 0.0 0.2 0.0 2.0 3.6 48.6 0.6 0.1 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 89.8 0.0 0.0 0.0 15.2 0.8 0.0 0.9 61.5 2.1 0.0 0.0 1.6 23.4 15.6 6.5 0.0 0.0 28.8 0.0 1.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 1.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 89.1 77.9 63.0 46.1 56.1 129.2 79.6 106.0 65.2 75.2 183.9 0.0 0.0 1.3 1.0 2.6 0.5 11.1 8.5 1.8 0.0 5.0 3.3 0.2 8.6 14.6 0.0 0.0 0.5 0.2 43.0 7.9 13.5 10.8 2.4 0.5 0.2 6.7 0.0 0.7 14.2 0.2 1.1 85.1 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 34.8 4.1 0.0 0.0 4.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 61.3 307.9 38.4 75.2 0.4 6.2 22.9 17.6 0.2 10.5 0.0 0.0 0.0 0.6 2.4 3.3 12.4 0.9 0.1 0.2 0.0 15.3 192.8 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 364.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 1141.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" 23.7 364.1 140.2 34.7 126.7 28.0 59.6 128.5 135.0 68.0 157.0 24.2 31.9 86.3 27.7 10.6 34.6 20.2 27.7 131.8 164.8 20.3 126.7 33.4 16.5 175.1 186.2 29.1 9.8 80.0 50.8 40.6 155.1 97.7 13.2 41.5 24.3 188.7 12.3 131.6 15.9 125.3 152.0 11.5 14.1 27.8 222.9 34.1 10.4 8.8 31.2 24.6 27.9 134.2 14.6 492.6 655.8 345.0 551.3 1141.8 167.2 86.3 658.3 109.0 288.2 31.4 149.6 3.8 11.4 172.3 167.8 15.7 436.4 709.5 52.7 6.9 11.8 297.9 106.5 72.0 421.9 18.9 15.9 430.9 25.8 383.4 39.1 170.3 324.4 254.4 17.9 212.1 52.0 13.5 166.4 104.7 291.5 0.7 150.1 206.1 13.9 663.1 392.1 4.4 197.4 260.8 49.9 1.4 23.5 164.0 21.5 197.7 139.2 14.0 120.5 9.8 13.1 115.7 110.3 39.7 13.0 96.3 131.2 4.4 6.0 6.9 8.5 8.7 2.0 1.4 3.1 4.6 10.1 3.7 1.8 3.8 2.8 6.6 7.4 13.0 2.9 4.9 140.2 126.7 128.5 135.0 131.8 164.8 175.1 186.2 155.1 152.0 222.9 134.2 3.2 9.6 18.8 69.9 2.0 1.7 1.3 26.9 0.0 9.1 4.7 3.0 4.2 1.5 15.1 3.7 4.2 1.7 5.2 0.5 0.0 6.9 2.2 4.7 57.7 12.2 5.4 26.7 7.4 17.8 22.0 21.0 5.1 9.5 5.1 28.3 2.5 55.8 20.5 5.0 7.7 0.2 22.4 7.2 3.1 5.3 25.7 7.0 8.8 15.0 20.7 32.1 8.2 38.7 11.9 5.1 0.0 23.7 1.4 16.9 0.1 0.7 5.4 13.2 0.0 23.8 29.5 1.3 0.5 1.2 0.6 3.1 2.5 28.3 2.0 0.9 FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.6;Extravillous trophoblasts: 138.4;Rod photoreceptor cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.7" "Group enriched" "Detected in many" 4 "B-cells: 8.7;granulocytes: 5.7;T-cells: 2.1" "Cell line enhanced" "Detected in all" "ASC diff: 283.2;HHSteC: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" 105.0 72.3 37.1 23.4 37.3 5.1 72.5 29.6 50.7 31.2 55.3 27.5 4.8 27.9 31.7 9.5 26.7 12.1 88.9 36.9 35.2 29.4 23.7 45.4 21.6 34.8 33.7 35.7 25.4 11.4 14.1 64.0 38.9 21.3 4.6 15.0 14.3 13.1 45.2 13.4 28.1 19.4 29.8 22.3 22.7 13.4 37.3 4.3 18.1 14.8 20.9 36.7 21.4 35.3 37.3 11.4 3.6 22.5 283.2 57.0 71.5 73.1 177.9 77.0 73.7 16.2 13.3 27.5 46.5 147.1 60.0 20.1 13.7 199.4 40.8 7.9 7.6 22.7 48.9 32.8 243.6 2.1 4.5 62.5 85.2 92.4 175.4 46.8 90.1 14.3 22.2 50.8 132.6 42.7 8.3 11.3 10.7 4.1 29.4 46.4 142.8 76.8 86.0 13.0 5.7 7.2 83.4 11.2 77.9 29.9 16.4 5.0 61.2 74.5 51.1 22.0 32.6 15.5 8.0 35.0 62.4 11.2 55.2 0.0 0.7 5.7 1.6 1.2 1.4 7.7 1.4 2.1 0.6 8.7 0.1 0.5 0.3 0.6 0.8 0.0 0.4 0.6 37.1 37.3 29.6 50.7 36.9 35.2 34.8 33.7 38.9 29.8 37.3 35.3 164.6 32.1 5.2 54.5 39.0 6.8 8.2 15.6 2.8 11.2 23.3 26.2 19.5 18.6 2.0 5.5 8.4 38.9 15.2 35.7 1.9 46.4 17.4 8.2 31.2 57.7 6.7 13.0 31.6 20.6 138.4 31.3 16.8 13.1 7.0 12.4 20.3 9.8 19.7 1.7 10.0 21.0 0.0 3.9 43.0 14.0 28.6 16.5 35.6 8.4 8.0 48.5 5.2 17.1 17.6 16.4 6.7 17.7 13.1 10.7 6.3 13.9 2.9 120.3 19.7 97.3 90.2 2.0 5.5 3.5 5.5 68.0 17.6 16.1 15.8 4.3 FADS6 ENSG00000172782 "Fatty acid desaturase 6" 17 74877302-74893781 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.7;epididymis: 18.2;intestine: 14.8" "Cell type enriched" "Detected in some" 13 "Proximal enterocytes: 72.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016802 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA016802: AB_2669448" "unprognostic (2.41e-2)" "unprognostic (6.80e-3)" "unprognostic (2.64e-1)" "unprognostic (4.68e-3)" "unprognostic (4.73e-2)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (6.41e-2)" "unprognostic (6.98e-4)" "unprognostic (3.38e-2)" "unprognostic (7.53e-2)" "unprognostic (1.14e-2)" "unprognostic (6.71e-2)" "unprognostic (2.27e-1)" "unprognostic (8.45e-2)" "unprognostic (1.79e-1)" 0.2 7.1 4.5 0.5 3.5 1.5 0.5 6.6 9.1 0.6 0.0 0.8 7.5 0.2 18.2 3.2 0.1 0.0 0.2 2.0 2.0 1.1 6.1 0.2 0.6 10.2 2.4 0.3 0.4 0.5 0.1 0.2 10.7 0.1 0.7 1.2 0.3 0.3 0.4 7.7 14.8 0.2 0.9 4.1 0.2 0.7 5.1 0.4 0.4 0.2 0.8 1.2 1.1 3.6 0.2 0.3 0.5 0.4 0.0 1.0 0.7 0.5 0.0 0.1 0.2 0.8 0.3 0.3 0.1 0.5 0.3 0.3 0.7 0.0 0.2 0.1 0.0 0.5 1.6 0.6 0.3 0.4 0.4 0.3 0.0 1.1 0.4 0.2 0.0 0.4 0.4 1.4 0.6 0.6 0.3 1.1 0.3 0.2 0.5 0.2 0.1 0.5 0.3 0.3 0.4 0.4 0.5 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.7 0.6 0.5 0.5 0.2 0.3 1.0 0.3 0.5 1.1 0.6 0.4 0.2 0.6 0.2 0.3 0.3 0.3 0.1 0.5 0.3 0.4 2.0 0.8 1.5 0.5 0.2 0.0 4.5 3.5 6.6 9.1 2.0 2.0 10.2 2.4 10.7 0.9 5.1 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 1.8 1.5 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.0 3.7 0.0 0.0 0.8 0.0 0.1 0.3 0.0 0.0 5.2 0.2 0.1 0.3 0.0 0.2 0.0 1.1 0.4 4.0 0.3 1.7 5.4 1.1 0.0 0.0 0.4 0.2 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.2 0.0 5.1 0.0 0.0 1.1 72.2 1.9 0.0 0.5 0.0 1.1 0.4 0.0 2.0 1.7 0.6 3.8 0.2 0.4 0.7 1.3 FAIM2 "KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2" ENSG00000135472 "Fas apoptotic inhibitory molecule 2" Q9BWQ8 12 49866896-49904217 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 359.4;parathyroid gland: 98.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 141.9;Early spermatids: 202.2;Excitatory neurons: 77.6;Horizontal cells: 232.2;Inhibitory neurons: 105.1" "Cancer enriched" "Detected in many" 8 "glioma: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.9" "Cell line enhanced" "Detected in some" "HHSteC: 12.2;OE19: 16.7;SH-SY5Y: 6.7;U-87 MG: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018790, HPA048800" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Intermediate filaments" "HPA018790: AB_1852822, HPA048800: AB_2680526" "unprognostic (1.74e-1)" "unprognostic (5.98e-4)" "unprognostic (2.22e-1)" "unprognostic (9.75e-3)" "unprognostic (3.36e-2)" "unprognostic (2.61e-4)" "unprognostic (2.62e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (1.75e-2)" "unprognostic (5.66e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-6)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.47e-1)" "unprognostic (6.78e-4)" 4.7 41.6 180.7 4.9 189.0 0.0 1.8 107.7 359.4 6.7 0.0 8.5 2.2 9.9 8.0 4.2 14.2 10.2 41.9 205.6 161.0 2.1 0.4 2.2 3.7 223.0 129.4 3.9 2.4 98.1 42.0 0.2 206.5 14.2 3.5 72.3 2.6 9.0 1.2 0.9 6.3 12.2 106.8 1.9 4.2 30.5 175.3 1.9 1.8 1.2 2.8 9.5 10.5 223.0 0.0 0.5 0.5 0.7 2.7 1.7 0.1 0.7 3.6 0.7 0.4 0.4 0.0 0.0 0.1 5.1 0.2 0.3 1.5 0.0 0.4 0.0 0.0 2.9 0.0 0.0 12.2 0.1 0.1 1.1 0.2 2.7 0.0 0.0 0.0 0.3 1.6 0.4 0.7 0.0 0.1 0.0 0.1 16.7 0.0 0.0 0.2 0.0 0.0 0.0 4.4 6.7 0.0 0.2 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.1 0.1 0.4 0.0 0.0 38.5 0.0 0.4 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.1 180.7 189.0 107.7 359.4 205.6 161.0 223.0 129.4 206.5 106.8 175.3 223.0 0.2 0.0 0.0 31.0 0.0 0.3 0.3 0.7 0.6 141.9 2.3 2.3 1.1 0.0 0.4 0.0 2.1 0.0 0.3 0.1 0.0 0.1 202.2 0.1 0.5 0.7 0.0 0.0 77.6 0.2 0.1 16.7 1.1 0.0 26.1 0.0 0.0 0.0 0.4 232.2 105.1 2.2 12.2 0.0 0.4 52.0 5.0 0.5 0.0 13.1 0.0 35.6 0.0 45.2 55.5 0.1 0.0 5.3 0.3 0.5 0.0 0.4 0.0 20.2 0.0 0.9 0.7 4.8 5.8 0.5 0.3 0.1 0.5 0.4 0.7 0.3 FAM155A ENSG00000204442 "Family with sequence similarity 155 member A" B1AL88 13 107163510-107867496 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.7;pituitary gland: 5.4" "Group enriched" "Detected in many" 6 "Astrocytes: 918.7;Excitatory neurons: 3051.8;Inhibitory neurons: 2146.4;Oligodendrocyte precursor cells: 2307.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 5.3;RPTEC TERT1: 11.4;SCLC-21H: 7.2;SH-SY5Y: 16.6;U-87 MG: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039453 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA039453: AB_10795290" "unprognostic (8.40e-2)" "unprognostic (9.98e-3)" "unprognostic (1.48e-1)" "unprognostic (3.38e-3)" "unprognostic (2.69e-1)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (5.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.08e-1)" "unprognostic (4.26e-1)" "unprognostic (9.06e-2)" "unprognostic (1.02e-5)" "unprognostic (5.56e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-2)" "unprognostic (3.69e-3)" 0.4 1.1 7.5 0.1 8.6 0.0 0.2 5.9 10.7 0.5 1.0 0.2 0.1 0.6 1.7 0.2 0.2 0.4 0.2 9.3 10.5 0.1 0.0 0.4 0.1 6.0 7.1 0.2 0.1 0.0 5.4 0.4 7.1 1.1 0.2 2.0 0.0 1.6 0.0 0.0 0.2 0.4 4.9 0.1 0.2 1.0 8.4 0.0 0.4 0.0 0.3 0.5 0.3 8.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.6 0.0 2.4 0.0 5.3 2.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 4.5 0.0 0.0 0.2 0.0 11.4 1.9 7.2 16.6 0.0 0.0 0.0 0.2 4.2 0.0 0.2 5.0 2.1 1.7 0.2 0.0 0.0 0.0 10.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 8.6 5.9 10.7 9.3 10.5 6.0 7.1 7.1 4.9 8.4 8.3 2.8 3.2 24.6 918.7 0.0 0.1 0.3 0.0 0.0 19.7 0.9 0.3 0.8 0.0 1.9 3.7 0.0 0.0 0.0 0.0 0.0 1.3 62.3 8.9 39.5 4.4 0.0 0.0 3051.8 0.0 0.1 3.7 0.0 20.7 0.0 0.5 8.2 0.0 0.2 37.0 2146.4 0.0 0.0 0.0 0.4 22.7 1.8 0.2 0.0 306.3 0.0 6.8 0.0 2307.6 37.2 0.5 0.0 1.2 0.0 0.9 0.0 0.1 0.0 1.6 6.6 0.3 1.5 1.1 2.0 0.1 0.0 0.0 0.4 1.0 0.0 0.3 FAM155B "CXorf63, TED, TMEM28" ENSG00000130054 "Family with sequence similarity 155 member B" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 7.4;HAP1: 16.2;Hep G2: 6.1;NTERA-2: 24.3;OE19: 6.5;SCLC-21H: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036093: AB_10673613" "prognostic unfavorable (4.61e-5)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "unprognostic (3.09e-4)" "unprognostic (7.07e-2)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (1.83e-4)" "prognostic favorable (6.63e-4)" "unprognostic (1.46e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-1)" "unprognostic (8.21e-2)" 0.1 0.8 2.2 0.0 2.1 0.0 0.2 3.0 2.6 0.2 0.5 0.3 0.1 0.3 0.4 0.1 0.7 0.2 43.5 2.1 2.7 0.9 0.2 0.1 0.1 2.4 3.1 0.1 1.8 3.1 2.4 0.0 3.4 0.9 0.2 0.4 1.1 4.9 0.1 0.0 0.2 0.1 2.0 0.7 1.1 1.5 3.5 0.1 8.0 0.0 0.1 0.2 0.1 2.3 0.0 2.7 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.7 0.0 5.2 0.0 0.0 0.0 16.2 0.6 0.0 0.0 5.0 0.0 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.2 0.0 0.0 24.3 6.5 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.8 0.1 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 3.0 2.6 2.1 2.7 2.4 3.1 3.4 2.0 3.5 2.3 0.2 0.0 0.0 1.3 0.0 0.0 0.3 1.6 0.0 0.4 0.6 0.1 23.7 0.0 0.8 1.8 0.0 0.0 0.0 0.5 0.0 0.5 0.0 2.0 0.5 0.7 1.2 0.0 0.8 1.2 0.0 0.4 0.0 4.4 0.0 0.0 0.4 0.3 0.1 0.0 0.9 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.8 0.2 0.0 0.0 1.2 0.0 0.5 0.3 0.8 0.0 0.1 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 FAM189B "C1orf2, cote1" ENSG00000160767 "Family with sequence similarity 189 member B" P81408 1 155247205-155255483 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006659, HPA050674" Uncertain Supported Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA006659: AB_1078339, HPA050674: AB_2681213" "unprognostic (1.56e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.59e-5)" "unprognostic (1.46e-2)" "unprognostic (4.86e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.70e-2)" "unprognostic (3.49e-2)" "unprognostic (2.73e-1)" "unprognostic (5.15e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.43e-7)" "unprognostic (4.16e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-3)" "unprognostic (3.25e-2)" 12.1 14.5 7.3 3.6 5.1 1.7 11.1 6.8 14.9 13.5 0.2 22.0 5.3 17.1 0.6 17.5 12.3 1.9 11.3 5.9 4.6 11.3 8.6 10.6 2.2 12.5 4.8 12.0 9.2 4.5 14.0 3.2 15.7 13.9 1.3 1.4 11.1 4.1 28.4 13.5 11.4 3.3 5.9 8.9 15.6 13.1 14.9 1.4 9.8 5.7 1.4 21.1 14.1 6.3 22.4 18.9 9.2 31.1 9.6 14.8 4.2 20.9 10.5 10.9 9.8 21.5 13.6 21.9 27.0 11.2 7.8 21.2 12.1 16.7 2.4 27.5 39.6 17.3 12.3 11.0 16.4 4.7 18.4 16.5 10.3 10.5 6.4 11.4 15.3 14.7 13.3 7.2 8.8 14.0 19.9 8.3 20.6 13.0 39.2 21.3 14.5 24.7 7.2 8.9 19.9 30.1 8.9 25.5 23.8 4.9 27.5 16.7 17.4 14.5 18.3 15.4 21.7 16.1 17.4 10.5 17.1 9.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.3 5.1 6.8 14.9 5.9 4.6 12.5 4.8 15.7 5.9 14.9 6.3 10.1 3.2 2.2 7.5 6.1 6.0 12.8 10.0 17.6 18.0 10.8 9.7 12.2 8.6 5.3 12.9 18.8 12.9 3.9 8.0 1.9 13.7 3.7 4.8 9.2 13.3 6.7 9.2 14.8 10.5 15.1 9.2 8.2 8.0 5.7 13.9 13.6 7.5 8.0 40.4 14.5 10.2 12.2 11.2 4.7 8.0 9.6 6.0 7.2 4.7 6.0 7.5 8.2 8.0 8.5 11.9 5.2 9.1 4.3 19.2 12.3 5.9 6.0 19.3 0.0 8.5 9.6 23.2 13.6 13.3 8.2 14.4 4.3 12.6 9.6 12.6 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.8;Breast glandular cells: 16.8;Collecting duct cells: 18.4;Erythroid cells: 13.2;Spermatogonia: 13.7" "Cancer enhanced" "Detected in all" "breast cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "HPA010803: AB_1079200, HPA010850: AB_2732402" "unprognostic (1.85e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-3)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (8.03e-3)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (3.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (5.22e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (7.62e-2)" 3.3 2.5 14.1 1.6 14.7 3.0 16.4 9.2 22.9 2.3 4.5 1.5 1.8 2.5 3.1 2.0 2.9 1.6 1.8 15.5 16.1 5.4 2.2 2.7 1.6 10.5 10.7 2.5 2.6 3.3 5.1 5.7 11.5 6.2 1.1 17.6 2.7 2.4 2.2 12.7 1.8 2.3 8.1 2.2 1.6 5.6 11.7 2.3 8.6 1.7 1.5 2.5 2.6 13.4 3.6 3.6 10.9 7.7 8.3 8.0 8.4 2.4 2.8 5.3 10.4 3.8 5.3 14.7 2.9 2.9 9.4 5.4 13.9 2.6 11.0 1.7 7.7 8.7 4.1 3.0 4.4 7.6 4.7 6.3 5.5 7.8 5.9 8.0 7.2 10.2 2.2 5.1 5.8 12.2 6.5 4.8 14.3 2.8 2.0 8.5 14.0 1.6 3.3 8.9 15.0 4.9 5.3 3.5 4.3 18.5 4.4 4.2 3.5 3.5 5.8 6.5 2.6 2.8 3.9 9.4 11.1 3.4 4.4 0.2 1.4 1.1 1.3 2.6 1.8 2.4 1.5 1.3 1.2 3.4 2.1 2.3 0.3 1.5 4.2 2.3 1.2 0.7 14.1 14.7 9.2 22.9 15.5 16.1 10.5 10.7 11.5 8.1 11.7 13.4 5.4 3.2 3.3 0.0 2.2 0.0 2.1 0.0 1.2 29.8 16.8 3.6 0.0 2.8 0.0 18.4 2.1 9.6 1.0 0.0 1.9 2.0 9.3 1.1 1.0 3.2 12.2 13.2 0.0 1.3 3.4 1.9 0.5 1.5 0.0 2.0 5.0 2.3 3.6 3.3 0.0 0.8 0.0 1.6 0.0 3.6 5.6 1.5 0.0 0.0 2.3 4.2 1.0 0.0 0.0 1.1 1.2 5.3 1.9 3.3 2.6 1.2 0.0 3.3 0.0 1.6 1.3 9.2 13.7 2.2 0.0 3.6 1.3 1.2 0.9 1.5 FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 437.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" 21.1 16.2 19.3 23.0 36.0 74.9 20.6 34.3 31.5 23.8 24.5 32.9 38.7 24.7 24.9 50.9 17.7 13.7 20.0 22.6 29.7 14.0 5.0 20.2 20.5 48.4 29.9 19.9 21.3 29.1 15.6 24.6 44.1 20.5 37.6 32.6 18.2 15.4 15.2 12.2 21.1 30.7 37.3 20.5 62.0 20.8 32.1 16.5 19.8 18.6 23.9 28.4 30.0 94.8 79.5 50.6 49.1 38.4 45.9 52.6 26.7 69.2 27.6 50.0 52.7 53.5 66.4 100.9 30.2 55.5 74.3 84.3 73.2 69.9 76.1 30.0 59.4 43.4 44.8 0.2 44.1 87.9 33.7 40.2 70.3 36.2 107.7 36.9 49.6 50.2 68.9 29.3 41.5 39.9 65.5 26.3 25.8 100.1 72.6 56.9 62.6 28.4 48.4 126.4 37.7 27.3 65.5 61.6 34.4 56.2 37.8 54.1 62.1 68.5 58.2 63.7 58.4 16.4 59.6 84.7 43.4 26.4 42.4 10.4 24.9 28.0 7.7 21.3 5.4 3.5 3.7 6.6 28.5 5.5 3.3 5.5 38.9 9.1 18.2 4.4 5.3 7.7 19.3 36.0 34.3 31.5 22.6 29.7 48.4 29.9 44.1 37.3 32.1 94.8 38.6 35.3 21.1 80.0 24.2 32.2 24.2 21.5 41.5 46.0 27.6 20.3 24.1 5.7 26.2 22.0 41.7 25.7 40.2 59.8 5.9 12.8 100.8 21.1 36.5 31.4 36.0 38.5 146.0 25.9 18.5 26.8 114.7 26.2 38.7 23.3 29.6 2.5 33.9 47.1 113.5 28.8 26.4 53.5 57.0 181.3 26.8 48.8 35.6 71.2 54.8 20.6 20.6 93.5 437.2 29.3 43.4 25.6 36.1 30.8 23.3 8.7 18.7 50.4 26.3 29.3 29.3 41.6 32.3 116.9 19.9 9.9 25.8 17.0 47.7 42.0 FAXDC2 "C5orf4, FLJ13758" ENSG00000170271 "Fatty acid hydroxylase domain containing 2" Q96IV6 5 154818492-154859252 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 304.9" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Erythroid cells: 93.5;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 34.8;ASC TERT1: 26.3;HSkMC: 23.2;hTERT-RPE1: 25.3;SK-MEL-30: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (6.38e-3)" "unprognostic (2.88e-2)" "unprognostic (6.26e-2)" "unprognostic (5.11e-2)" "unprognostic (3.12e-2)" "unprognostic (2.70e-2)" "prognostic favorable (3.87e-5)" "unprognostic (8.29e-2)" "unprognostic (2.52e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (3.42e-2)" "prognostic favorable (9.71e-10)" "unprognostic (1.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.07e-3)" "unprognostic (3.94e-1)" 34.7 37.5 49.9 5.8 79.0 34.4 27.0 73.6 57.1 24.3 63.0 46.3 8.8 34.7 55.7 16.9 37.4 30.4 34.0 49.0 57.9 25.4 139.7 36.7 7.3 76.4 72.0 59.4 15.0 304.9 12.1 12.6 74.8 28.0 17.8 10.2 40.5 31.0 12.5 21.9 16.2 37.8 60.4 13.3 17.7 12.1 66.6 5.9 36.7 24.3 4.1 19.5 17.2 101.9 1.6 1.3 5.0 10.5 34.8 26.3 3.9 3.7 10.5 1.4 6.4 1.3 13.5 1.9 2.2 5.8 0.3 1.3 0.1 1.7 1.3 1.1 1.7 20.5 3.5 7.4 5.1 2.6 1.7 23.2 6.6 3.3 0.8 25.3 7.9 1.4 11.8 0.3 8.8 0.5 1.5 3.9 2.4 5.0 0.4 1.6 3.3 0.7 2.3 1.4 0.5 9.0 1.6 0.9 24.6 10.6 0.6 0.6 2.8 3.6 2.2 1.5 1.1 1.5 1.1 1.3 5.0 1.5 2.2 3.5 0.8 1.3 0.4 0.6 0.4 0.4 0.5 0.4 1.1 1.1 0.4 0.6 4.2 2.4 0.5 0.6 0.3 6.6 49.9 79.0 73.6 57.1 49.0 57.9 76.4 72.0 74.8 60.4 66.6 101.9 14.3 41.7 11.8 58.8 1.3 2.9 12.3 2.0 7.4 1.6 7.1 8.8 17.8 12.8 6.8 9.2 0.0 4.2 0.3 4.0 9.8 3.4 12.9 6.9 14.9 14.3 3.0 93.5 5.5 0.7 0.4 22.6 2.0 1.9 6.3 14.5 21.8 44.3 2.1 3.3 4.7 29.8 2.0 11.6 9.1 11.2 47.2 17.0 5.4 37.5 2.6 46.8 3.1 51.3 164.8 12.8 5.5 50.8 0.2 4.0 4.2 2.9 15.0 1.8 0.0 24.5 9.4 2.5 0.8 0.7 3.7 1.4 1.9 11.9 1.2 3.8 FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Daudi: 133.1;RPMI-8226: 361.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favorable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favorable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" 69.1 126.7 8.2 6.7 14.9 15.0 69.5 13.1 11.6 93.3 7.4 113.4 6.7 80.2 2.9 165.7 59.4 3.2 62.9 10.0 11.7 71.3 118.3 88.0 6.0 29.9 14.1 66.9 58.6 2.0 51.2 4.2 23.1 64.5 5.8 5.4 141.7 3.1 160.3 129.0 92.2 4.9 15.4 50.4 113.2 118.7 15.3 3.2 45.9 6.9 4.5 70.4 107.8 31.9 19.1 8.1 28.8 19.4 3.8 5.7 10.9 19.2 10.6 7.4 8.6 8.1 14.1 133.1 3.9 3.2 34.6 17.8 10.6 24.7 8.2 13.1 17.2 9.6 11.1 21.7 7.4 5.5 13.0 11.2 6.0 13.2 4.7 5.3 2.1 24.5 12.1 60.0 4.6 11.1 16.7 12.9 27.1 9.0 5.3 14.9 11.3 361.0 11.9 61.5 9.6 11.2 4.3 11.2 35.9 12.3 11.6 6.8 11.3 5.1 21.6 3.1 5.8 17.0 30.2 26.3 7.5 18.7 19.7 52.1 19.5 25.5 23.1 23.6 20.7 60.5 25.3 24.5 29.1 45.6 25.7 23.3 22.3 26.7 15.1 27.9 45.7 43.9 8.2 14.9 13.1 11.6 10.0 11.7 29.9 14.1 23.1 15.4 15.3 31.9 31.1 54.5 164.1 67.6 78.0 52.5 94.0 479.6 87.6 17.7 79.6 49.8 78.5 101.5 325.8 79.1 14.6 266.2 49.4 134.8 88.0 165.6 294.4 55.0 20.9 45.2 79.1 113.2 29.3 284.4 153.3 37.1 64.2 68.1 57.0 86.2 22.1 221.8 94.1 11.8 25.6 117.4 284.8 41.9 32.2 228.8 77.0 54.3 101.4 38.4 97.1 61.9 55.6 30.2 95.6 163.6 108.4 53.4 50.0 101.3 87.0 74.9 142.6 21.0 52.6 13.8 74.4 215.5 76.1 112.5 88.8 175.0 55.7 131.4 100.4 167.2 FITM1 FIT1 ENSG00000139914 "Fat storage inducing transmembrane protein 1" A5D6W6 14 24130659-24132849 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 171.1;skeletal muscle: 224.1" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 281.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.0;HMC-1: 1.2;RH-30: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA019842 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA019842: AB_1853025" "unprognostic (1.81e-2)" "unprognostic (4.29e-7)" "unprognostic (2.77e-1)" "unprognostic (2.02e-3)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "prognostic favorable (1.00e-3)" "unprognostic (1.20e-4)" "unprognostic (4.57e-1)" "unprognostic (2.12e-2)" "unprognostic (2.84e-2)" "unprognostic (3.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.86e-2)" "unprognostic (5.62e-1)" "unprognostic (1.96e-1)" "unprognostic (2.12e-3)" 1.0 7.3 0.7 0.2 0.8 1.7 1.2 1.1 1.1 0.9 0.6 1.3 0.9 0.8 0.5 1.3 0.8 0.2 171.1 0.6 0.7 1.8 27.0 1.4 0.5 0.8 0.7 1.4 15.5 0.1 1.5 0.1 0.8 3.3 0.3 0.8 7.4 0.4 224.1 1.6 2.3 0.0 0.6 10.2 1.3 2.2 0.7 0.4 2.0 1.7 0.2 0.7 0.9 1.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.1 0.2 2.0 0.2 0.0 1.2 0.2 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.3 0.2 0.2 0.2 0.6 0.0 0.0 0.3 0.3 2.0 0.0 0.1 0.3 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.2 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 1.1 1.1 0.6 0.7 0.8 0.7 0.8 0.6 0.7 1.0 2.7 0.0 0.0 0.0 0.6 0.1 0.3 0.4 0.0 1.8 1.3 0.9 281.6 1.5 0.2 0.0 0.0 0.2 1.1 1.9 0.0 1.0 2.2 0.5 0.3 5.0 1.2 0.0 0.3 3.0 0.2 12.2 1.1 0.9 0.0 0.6 1.1 37.4 0.2 0.0 0.2 1.1 0.0 0.8 0.3 3.9 0.0 0.4 0.0 0.0 0.9 0.9 2.1 0.0 0.4 0.8 0.3 0.7 0.2 0.3 3.8 0.6 0.3 0.7 0.0 56.8 7.5 1.5 0.3 0.7 0.6 0.7 0.8 12.3 0.9 0.2 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMR1NB "CT37, FLJ25736, NY-SAR-35" ENSG00000176988 "FMR1 neighbor" Q8N0W7 X 147981337-148026665 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 333 "testis: 58.1" "Group enriched" "Detected in some" 10 "Spermatocytes: 502.2;Spermatogonia: 296.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "U-266/70: 67.5;U-266/84: 57.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA011284, CAB026403" Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "CAB026403: , HPA011284: AB_1078898" "unprognostic (2.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.83e-1)" "unprognostic (4.38e-2)" "unprognostic (4.11e-3)" "unprognostic (2.85e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 67.5 57.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.1 0.1 0.0 0.5 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 18.4 5.6 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 39.5 0.0 0.0 502.2 296.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.0;Hofbauer cells: 12.7;Kupffer cells: 18.8;Late spermatids: 26.8;Macrophages: 61.3;monocytes: 23.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Cell line enriched" "Detected in some" 20 "U-937: 32.7" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" 13.6 1.2 0.3 56.1 0.6 16.6 0.6 0.3 2.6 0.5 0.9 0.8 1.0 0.5 0.1 1.8 1.8 5.9 0.9 0.3 0.3 0.4 4.9 9.4 1.9 0.6 0.5 1.5 2.3 0.3 0.2 7.6 0.9 0.4 0.5 0.1 0.5 0.3 0.3 0.4 1.3 6.7 0.3 17.2 0.7 2.4 1.2 1.6 0.7 4.2 0.8 15.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.9 32.7 0.0 3.6 122.0 5.8 0.2 122.7 0.7 0.1 0.2 0.2 16.6 0.2 0.1 0.2 1187.9 0.2 85.0 3.3 0.1 46.0 0.3 0.6 0.3 2.6 0.3 0.3 0.6 0.5 0.9 0.3 1.2 0.5 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 9.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 5.1 0.0 0.4 0.4 12.7 0.0 0.0 0.0 0.0 18.8 0.8 26.8 0.0 61.3 0.0 0.0 23.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.5;salivary gland: 66.2;stomach 1: 28.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 56.4;Club cells: 69.4;Distal enterocytes: 110.0;Gastric mucus-secreting cells: 83.6;Ionocytes: 57.0;Paneth cells: 75.5;Proximal enterocytes: 182.4;Undifferentiated cells: 62.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 63.6;OE19: 76.1" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.2 0.6 0.8 6.2 0.9 0.3 1.7 5.5 1.2 16.0 0.0 23.5 44.5 1.1 0.1 26.0 2.6 13.5 0.5 0.9 0.0 1.0 0.3 0.9 0.5 0.2 0.1 1.1 5.2 0.1 2.0 0.1 0.3 1.4 19.8 0.9 66.2 2.9 0.7 4.8 21.9 0.8 0.0 0.6 28.9 0.8 0.4 0.6 0.7 0.0 6.6 6.3 9.7 0.6 2.0 1.5 0.3 0.9 0.0 0.0 0.2 0.2 0.0 0.0 0.0 7.2 63.6 0.7 0.5 0.0 0.3 10.6 0.0 0.0 0.0 0.5 0.5 0.6 0.6 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.0 1.0 0.0 1.2 0.1 0.8 0.1 0.5 0.7 1.5 0.4 76.1 0.3 0.5 0.2 3.0 0.0 0.6 3.4 0.5 0.3 0.6 0.1 0.4 9.5 0.1 0.3 0.4 0.4 0.5 0.2 0.7 0.5 0.1 0.3 0.4 0.2 1.1 0.1 0.1 0.4 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.4 0.1 0.5 0.2 0.1 0.4 0.6 0.2 0.8 0.9 5.5 1.2 0.9 0.0 0.2 0.1 0.3 0.0 0.4 0.6 0.5 0.0 0.6 0.7 0.6 0.9 2.3 56.4 5.7 2.5 6.1 3.0 0.8 32.9 69.4 20.2 2.1 0.1 0.4 110.0 1.9 4.7 0.5 8.4 2.7 0.7 11.4 0.0 2.3 46.5 0.0 0.5 83.6 23.9 0.0 0.1 0.0 0.1 0.1 0.0 1.4 42.1 57.0 0.3 0.3 0.2 0.0 0.3 1.8 0.0 0.3 0.5 2.1 0.5 1.2 31.8 75.5 0.0 0.2 2.9 182.4 0.1 37.8 4.2 0.0 1.2 2.4 0.3 0.2 9.9 1.4 0.1 0.8 0.3 62.9 19.4 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FXYD6-FXYD2 ENSG00000255245 "FXYD6-FXYD2 readthrough" 11 117820163-117876667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.5;salivary gland: 4.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 97.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MOLT-4: 6.5;RPTEC TERT1: 7.3" "HPA068838, HPA075209" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear membrane, Vesicles" "HPA068838: AB_2686047, HPA075209: AB_2732285" 0.3 0.2 0.4 0.0 0.4 0.0 0.2 0.5 0.5 0.4 0.2 0.9 0.1 1.0 0.8 0.1 0.6 0.9 0.6 0.4 0.4 7.5 0.2 0.4 0.0 0.3 0.3 1.3 1.9 0.0 0.3 0.2 0.3 0.3 0.0 0.0 4.5 0.1 0.2 0.1 0.3 0.3 0.3 0.9 0.3 0.3 0.3 0.4 0.3 0.2 0.1 0.4 0.2 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.5 0.4 0.4 0.3 0.3 0.3 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.6 0.0 11.0 0.0 0.0 0.0 0.0 97.8 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 2.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 15.8 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901291-168910000 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 38 "pancreas: 30.9;retina: 12.3" "Group enriched" "Detected in some" 13 "Early spermatids: 17.8;Muller glia cells: 53.0" "Cancer enriched" "Detected in single" 92 "pancreatic cancer: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (6.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.04e-2)" "unprognostic (9.05e-2)" "unprognostic (2.97e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-2)" "unprognostic (1.87e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.3 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.0 0.0 53.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GASK1B "C4orf18, DKFZp434L142, ENED, FAM198B, FLJ38155" ENSG00000164125 "Golgi associated kinase 1B" Q6UWH4 4 158124474-158173318 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 206.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.9;Cardiomyocytes: 33.8;Endothelial cells: 12.1;Fibroblasts: 14.5;Hofbauer cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "classical monocyte: 50.6;intermediate monocyte: 28.8;myeloid DC: 15.1;non-classical monocyte: 14.0" "Group enriched" "Detected in many" 41 "dendritic cells: 15.1;monocytes: 50.6" "Cell line enhanced" "Detected in many" "ASC diff: 77.0;ASC TERT1: 143.3;HSkMC: 166.4;HUVEC TERT2: 193.3;WM-115: 74.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007227 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA 13000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA007227: AB_1847689" "unprognostic (4.87e-2)" "unprognostic (7.79e-2)" "unprognostic (6.60e-3)" "unprognostic (9.42e-3)" "unprognostic (2.37e-2)" "unprognostic (7.47e-2)" "unprognostic (2.13e-2)" "unprognostic (7.49e-2)" "unprognostic (9.20e-3)" "unprognostic (1.71e-1)" "unprognostic (1.60e-1)" "unprognostic (1.89e-1)" "unprognostic (3.25e-3)" "unprognostic (3.74e-3)" "unprognostic (3.85e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-2)" 73.9 206.2 29.0 39.8 29.2 2.8 47.3 21.8 23.3 47.0 11.9 23.4 13.3 77.7 21.8 17.2 19.4 37.1 77.9 28.7 29.6 9.5 8.6 14.1 11.2 51.7 33.0 140.3 14.2 11.5 2.8 29.0 26.9 23.6 23.3 0.8 23.6 30.0 12.4 7.3 18.5 70.2 34.1 20.8 11.8 10.4 35.5 5.7 17.7 16.7 6.8 43.2 9.2 33.0 12.5 9.9 6.1 1.1 77.0 143.3 11.4 3.1 2.4 0.6 3.7 13.3 4.9 0.1 0.3 5.0 5.1 0.2 70.7 18.9 1.8 0.1 0.2 1.0 0.0 37.0 51.4 0.6 0.3 166.4 4.6 24.2 2.6 8.0 193.3 0.0 13.0 0.0 35.7 0.8 0.0 0.2 0.4 43.4 0.2 0.1 0.5 0.2 0.0 27.5 0.4 0.1 0.0 27.8 8.2 33.4 5.4 0.3 9.3 16.0 17.1 9.6 6.1 0.0 0.1 44.8 2.5 0.3 74.3 0.1 50.6 0.0 0.1 28.8 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.7 0.1 14.0 0.6 0.0 17.8 29.0 29.2 21.8 23.3 28.7 29.6 51.7 33.0 26.9 34.1 35.5 33.0 22.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 1.2 14.5 0.0 0.0 0.0 0.0 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 GDAP1 "CMT2K, CMT4, CMT4A" ENSG00000104381 "Ganglioside induced differentiation associated protein 1" Q8TB36 8 74320613-74518007 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.9;Cone photoreceptor cells: 47.9;Excitatory neurons: 75.7;Horizontal cells: 47.1;Inhibitory neurons: 67.3;Oligodendrocyte precursor cells: 67.8;Rod photoreceptor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014266, HPA024334" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria Cytosol "HPA014266: AB_1849581, HPA024334: AB_1849583" "unprognostic (3.19e-2)" "unprognostic (1.52e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (3.31e-1)" "unprognostic (4.36e-2)" "unprognostic (1.72e-2)" "prognostic favorable (2.68e-4)" "unprognostic (3.88e-1)" "unprognostic (4.17e-1)" "unprognostic (9.44e-3)" "unprognostic (2.44e-1)" "unprognostic (5.40e-2)" "unprognostic (3.29e-1)" "unprognostic (6.99e-2)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.73e-1)" 2.7 9.6 19.0 3.3 22.5 1.2 4.0 15.2 26.0 2.9 4.9 2.5 2.4 3.9 1.9 4.0 2.8 2.5 2.1 25.3 19.7 4.2 1.5 2.4 3.3 14.5 17.0 6.0 7.4 12.4 20.6 1.2 18.1 4.1 2.4 19.0 2.4 4.1 2.7 1.7 2.3 2.8 12.2 1.9 2.0 4.7 16.7 4.5 6.6 3.1 2.8 3.9 2.6 20.5 3.5 16.8 17.7 4.8 1.2 1.6 1.5 1.8 8.2 8.3 9.5 7.8 5.0 14.8 2.5 1.2 10.6 6.6 12.4 7.0 16.2 19.7 3.6 7.4 8.9 14.0 0.7 7.6 15.8 4.7 2.3 5.3 8.2 0.9 1.1 7.3 3.4 0.3 4.8 5.7 12.6 0.4 20.1 24.5 17.9 8.7 9.2 3.2 2.9 15.3 18.2 38.9 13.1 3.4 9.7 4.9 14.9 2.6 0.0 11.7 6.2 2.9 5.5 9.3 15.7 6.8 7.3 0.3 13.8 0.5 0.9 1.0 0.8 3.1 1.0 1.4 0.8 1.3 0.8 1.3 0.6 0.6 1.8 0.7 5.5 0.2 4.0 0.8 19.0 22.5 15.2 26.0 25.3 19.7 14.5 17.0 18.1 12.2 16.7 20.5 6.4 6.4 5.1 27.1 5.9 1.8 7.4 4.2 6.2 46.9 6.2 6.1 5.9 5.7 3.6 3.7 47.9 0.4 3.9 2.1 9.8 5.2 5.4 15.4 7.0 6.7 20.4 2.1 75.7 5.8 0.3 4.8 3.1 2.8 17.2 2.1 6.4 1.8 4.7 47.1 67.3 1.7 12.2 6.3 2.5 1.3 4.1 4.6 1.8 15.0 2.9 23.5 4.1 67.8 41.9 3.7 1.4 5.7 2.6 2.6 3.6 6.6 4.9 47.7 0.0 8.0 5.5 14.7 13.1 3.7 1.3 0.0 3.1 6.5 1.7 3.8 GDAP1L1 ENSG00000124194 "Ganglioside induced differentiation associated protein 1 like 1" Q96MZ0 20 44247099-44280947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 30.7;pituitary gland: 17.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Early spermatids: 9.8;Excitatory neurons: 20.9;Horizontal cells: 15.2;Inhibitory neurons: 23.4;Late spermatids: 30.4;Oligodendrocyte precursor cells: 10.1" "Cancer enriched" "Detected in single" 14 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 12.5;SCLC-21H: 32.3;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054182, HPA063265" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "HPA054182: , HPA063265: AB_2684972" "unprognostic (6.58e-3)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-4)" "unprognostic (3.69e-1)" "unprognostic (5.15e-1)" "unprognostic (6.45e-2)" "unprognostic (7.69e-2)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (4.74e-3)" "unprognostic (2.41e-1)" "unprognostic (3.81e-5)" "unprognostic (8.57e-2)" "unprognostic (1.87e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-1)" 0.1 2.2 21.6 0.2 27.0 0.1 0.1 14.2 30.7 1.1 0.1 0.6 0.0 0.6 0.0 0.0 0.2 0.0 1.6 26.6 15.4 0.1 0.1 0.0 0.0 17.0 10.5 2.7 0.5 0.9 17.7 0.0 15.8 0.2 0.0 5.7 0.0 0.0 0.0 0.3 0.3 0.1 6.2 0.0 0.7 3.5 14.0 0.0 0.2 0.0 0.0 0.1 0.3 21.2 0.0 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.1 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.3 14.8 0.0 0.1 1.5 0.2 0.0 3.9 0.1 1.1 0.7 0.3 0.0 0.0 0.2 0.8 1.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 27.0 14.2 30.7 26.6 15.4 17.0 10.5 15.8 6.2 14.0 21.2 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.1 0.2 0.0 0.0 20.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 15.2 23.4 0.4 0.0 0.0 0.0 30.4 0.6 0.0 0.0 6.5 0.0 1.1 0.0 10.1 3.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 GDPD1 "FLJ37451, GDE4" ENSG00000153982 "Glycerophosphodiester phosphodiesterase domain containing 1" Q8N9F7 17 59220467-59275970 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Early spermatids: 47.2;Excitatory neurons: 65.1;Inhibitory neurons: 63.9;Oligodendrocyte precursor cells: 34.2;Oligodendrocytes: 36.5;Spermatocytes: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 22.3;K-562: 12.5;SCLC-21H: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (8.33e-2)" "unprognostic (6.63e-3)" "unprognostic (2.68e-2)" "unprognostic (5.98e-3)" "unprognostic (7.12e-2)" "unprognostic (5.35e-2)" "unprognostic (4.85e-6)" "prognostic favorable (2.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.36e-2)" "unprognostic (1.24e-3)" "unprognostic (2.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-3)" "unprognostic (4.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.28e-3)" 0.8 1.8 4.7 0.9 4.3 1.5 1.8 7.0 8.4 1.1 1.9 1.8 5.7 1.5 0.7 0.8 1.4 1.8 1.1 5.1 4.7 2.0 1.0 2.3 0.9 5.9 5.4 0.9 1.1 5.9 1.8 1.3 6.3 2.0 1.5 5.8 2.3 1.5 1.7 1.4 4.2 1.3 2.8 1.5 5.2 8.6 5.1 1.6 2.6 0.7 1.1 1.3 0.8 5.4 0.8 1.0 4.2 3.2 0.6 0.2 2.6 0.5 1.6 0.4 3.3 0.0 1.3 2.0 4.7 0.1 3.0 0.6 6.6 1.1 1.9 2.6 6.8 22.3 0.7 3.2 2.0 1.0 3.2 0.6 5.4 2.1 0.6 1.9 1.9 4.9 12.5 1.3 0.8 1.0 3.9 0.4 0.8 6.6 1.1 2.4 0.4 2.1 2.0 1.2 12.5 3.4 1.0 0.4 4.6 1.3 3.0 1.4 1.6 0.2 1.3 0.2 0.4 3.7 2.3 0.7 1.0 1.2 1.4 2.4 0.5 0.3 0.5 0.7 0.4 0.3 0.4 0.6 0.2 0.5 0.5 0.7 0.9 0.8 0.7 0.7 0.3 0.3 4.7 4.3 7.0 8.4 5.1 4.7 5.9 5.4 6.3 2.8 5.1 5.4 1.6 3.2 8.2 34.3 1.3 0.5 1.5 1.2 1.8 6.1 1.6 1.0 3.1 0.0 8.7 5.5 10.4 0.4 3.2 0.9 0.0 2.2 47.2 1.8 0.4 1.4 1.2 11.3 65.1 1.8 5.5 1.1 9.2 0.7 0.0 4.0 0.7 0.6 1.9 6.7 63.9 3.1 6.1 2.6 1.0 8.3 0.6 3.0 1.8 2.8 2.7 2.3 3.1 34.2 36.5 1.6 2.0 1.5 0.9 1.2 7.6 0.5 5.6 4.4 0.0 1.6 5.7 52.4 17.7 0.5 0.4 2.3 2.5 2.2 1.2 1.6 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" Neurogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6;retina: 83.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 60.9;Cone photoreceptor cells: 148.0;Early spermatids: 52.1;Late spermatids: 178.0;Rod photoreceptor cells: 88.4;Syncytiotrophoblasts: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "EFO-21: 32.8;fHDF/TERT166: 32.4;HDLM-2: 66.9;U-2 OS: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" 31.0 8.7 19.5 4.8 22.1 12.8 24.6 17.4 12.9 12.4 6.0 7.3 2.7 17.9 1.8 3.3 10.3 4.3 9.5 10.5 14.5 7.8 8.1 15.2 6.7 14.2 27.0 7.3 38.1 0.8 19.1 14.0 10.2 11.5 1.6 83.5 21.3 5.3 13.1 7.4 10.0 6.5 7.4 116.6 4.8 38.9 42.1 3.1 7.7 8.7 4.7 12.6 9.9 12.4 2.1 7.5 3.2 3.7 2.2 1.1 11.1 2.3 3.1 1.1 0.7 10.0 4.4 14.2 32.8 32.4 8.1 4.7 4.0 3.8 0.6 66.9 3.1 2.6 11.7 21.2 3.2 1.6 10.7 2.4 2.0 0.8 1.6 3.2 26.7 12.7 4.7 6.3 1.5 4.5 3.9 7.1 5.7 3.7 10.6 4.5 0.9 3.9 0.9 3.6 1.7 1.2 4.8 18.3 9.3 4.1 2.7 6.3 7.9 7.5 30.4 5.8 2.6 1.6 0.3 2.8 1.7 8.5 0.8 7.7 0.8 0.5 1.2 0.3 1.7 0.6 1.3 0.9 0.2 0.2 0.7 0.9 0.1 0.0 0.0 0.7 2.0 0.5 19.5 22.1 17.4 12.9 10.5 14.5 14.2 27.0 10.2 7.4 42.1 12.4 4.2 6.4 0.0 1.6 5.4 1.0 0.3 0.7 0.6 60.9 3.6 3.4 3.0 1.5 1.3 0.0 148.0 3.2 9.1 0.5 0.0 4.2 52.1 1.0 10.4 7.0 0.0 8.2 5.0 9.3 1.5 6.6 1.1 1.5 4.5 1.6 20.7 2.4 1.9 5.0 15.8 0.7 0.0 2.8 3.7 178.0 5.9 3.1 5.4 8.4 4.9 8.9 1.0 1.0 0.8 4.7 0.3 2.6 5.0 0.8 0.3 0.1 0.8 88.4 0.0 4.6 1.9 12.9 8.2 0.1 1.1 46.0 7.0 0.9 2.0 0.6 GET1 "CHD5, WRB" ENSG00000182093 "Guided entry of tail-anchored proteins factor 1" O00258 21 39377698-39428528 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 12.0;Cardiomyocytes: 38.3;Cytotrophoblasts: 37.6;Extravillous trophoblasts: 35.3;Fibroblasts: 10.4;Hofbauer cells: 31.5;Syncytiotrophoblasts: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018527 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018527: AB_1858860" "unprognostic (4.34e-3)" "unprognostic (3.28e-1)" "unprognostic (2.88e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (5.08e-2)" "unprognostic (6.86e-2)" "unprognostic (1.57e-3)" "unprognostic (8.74e-2)" "unprognostic (1.15e-2)" "unprognostic (4.02e-3)" "unprognostic (9.48e-2)" "unprognostic (6.50e-3)" "unprognostic (2.21e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-3)" "unprognostic (8.13e-2)" 20.4 44.4 63.7 11.8 66.5 8.9 25.6 65.3 92.7 28.1 85.3 20.4 18.5 29.4 45.8 15.3 71.1 18.8 29.4 65.6 77.8 38.6 33.4 18.9 14.4 65.3 69.1 41.8 17.9 15.6 29.1 22.1 69.8 24.7 14.9 111.3 16.1 21.1 38.1 10.1 18.7 23.2 67.9 13.7 17.4 55.9 73.3 15.9 28.5 30.1 14.8 16.1 15.1 74.2 36.8 33.2 58.9 34.6 74.8 69.7 18.6 50.6 51.2 23.8 21.7 31.2 50.3 59.6 35.0 54.9 29.0 13.8 47.5 31.8 33.5 26.4 32.2 43.0 28.5 50.8 44.7 33.3 15.8 44.8 30.3 37.9 34.7 67.0 60.2 61.2 65.8 36.8 63.4 82.4 38.4 25.3 52.8 66.7 25.0 42.1 34.6 44.4 69.1 19.1 29.2 44.5 44.7 23.1 53.9 31.1 43.1 37.7 35.6 30.2 10.6 41.2 23.0 46.4 70.4 27.3 72.3 55.3 34.2 37.7 26.7 27.6 19.8 20.4 17.6 30.8 24.1 20.8 30.7 20.6 27.0 25.6 47.1 27.3 21.2 39.4 23.8 39.5 63.7 66.5 65.3 92.7 65.6 77.8 65.3 69.1 69.8 67.9 73.3 74.2 12.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.0 37.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 35.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 13.7 0.6 0.0 0.0 0.0 GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 184.2;Intestinal goblet cells: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 93000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favorable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" 31.2 17.9 6.6 21.5 6.5 15.0 22.4 5.5 7.1 37.8 31.5 74.3 38.4 15.6 41.6 16.4 24.3 32.5 24.8 7.0 11.0 21.6 23.1 17.0 10.6 4.9 10.5 12.0 33.7 26.2 18.9 36.0 10.8 36.7 76.6 10.4 42.4 25.9 10.2 6.0 41.2 23.2 5.3 9.5 64.3 46.6 8.0 10.2 91.8 13.9 15.9 21.8 9.2 6.8 46.6 42.7 34.7 20.9 107.7 75.8 73.5 97.1 94.5 44.7 59.3 109.5 50.5 31.7 31.9 92.9 61.4 22.6 47.1 28.6 73.6 38.4 18.4 38.2 25.0 94.5 123.0 27.9 17.9 47.8 132.5 88.7 158.8 55.5 43.4 29.8 34.8 58.3 85.2 30.9 31.3 22.9 37.0 116.7 27.4 28.2 79.1 18.3 70.6 42.0 25.2 11.9 35.2 52.4 93.7 73.5 22.7 17.2 61.8 37.2 62.3 64.6 47.5 39.5 32.2 25.4 65.7 18.3 46.9 9.2 3.5 4.9 7.5 4.3 7.0 6.4 6.5 8.3 4.7 3.6 6.3 6.2 1.2 5.2 5.2 4.4 5.0 4.2 6.6 6.5 5.5 7.1 7.0 11.0 4.9 10.5 10.8 5.3 8.0 6.8 14.6 51.3 49.5 15.7 29.8 28.4 21.6 31.7 26.7 13.7 50.6 16.5 43.1 42.9 54.5 44.1 12.5 28.6 30.3 184.2 17.6 34.1 123.9 54.4 54.1 17.2 75.1 3.8 49.2 89.5 70.3 37.6 110.1 60.0 24.1 19.2 17.9 53.6 17.0 6.7 56.3 244.0 16.2 10.0 31.4 23.7 23.3 16.0 53.4 27.2 28.1 10.6 13.4 42.7 43.8 66.0 83.3 28.2 82.1 72.3 62.5 30.0 89.7 14.0 19.7 21.6 41.8 134.1 45.3 20.3 21.0 34.3 33.4 15.7 135.3 56.3 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.8;intestine: 53.4;salivary gland: 55.8;skin 1: 56.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 208.5;Intestinal goblet cells: 69.4;Paneth cells: 135.8;Proximal enterocytes: 130.9;Undifferentiated cells: 86.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "RT4: 58.5;SK-BR-3: 19.4;T-47d: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 6: Non-specific - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.6 0.4 5.0 0.5 0.2 9.0 0.7 0.7 7.9 0.4 53.4 44.5 0.4 41.1 53.8 8.5 5.3 0.0 0.5 0.3 39.2 0.4 3.5 0.0 0.5 0.4 0.5 46.8 0.0 0.5 0.0 0.5 6.5 34.0 0.1 55.8 6.4 0.4 56.2 38.4 0.8 0.2 0.1 23.7 0.7 0.4 0.7 0.2 0.0 9.0 18.4 18.8 0.9 3.6 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 6.3 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 58.5 0.2 0.2 0.0 19.4 0.0 0.0 60.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.7 0.7 0.5 0.3 0.5 0.4 0.5 0.2 0.4 0.9 0.1 35.3 6.9 0.0 1.1 4.1 14.7 12.5 5.2 0.0 17.9 11.0 0.2 20.0 38.0 23.9 2.1 0.0 0.3 208.5 21.5 23.8 0.1 7.4 0.3 0.5 6.0 0.0 0.0 38.2 0.0 0.9 24.5 2.6 0.0 0.1 0.4 0.0 0.1 0.0 0.0 69.4 12.2 0.0 1.8 0.2 0.6 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.0 10.6 135.8 0.0 0.0 5.5 130.9 39.5 45.9 0.3 0.0 0.4 2.3 0.0 0.1 30.6 20.9 0.0 1.0 0.0 86.1 26.7 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.9;Inhibitory neurons: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1900000 "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 13.2 13.8 37.0 11.8 35.8 5.5 15.4 43.4 43.8 25.6 53.2 19.1 16.0 19.3 29.1 10.1 21.1 18.2 22.3 38.6 33.3 24.9 16.8 14.4 18.2 34.3 28.9 24.1 27.1 22.9 40.5 13.7 33.6 24.8 14.9 22.7 30.8 22.6 67.5 17.9 20.1 14.9 22.5 15.4 22.1 10.1 32.0 15.8 28.8 13.8 13.6 19.7 18.0 35.4 5.2 7.7 38.5 39.5 29.7 26.4 34.2 21.7 21.9 17.5 26.0 40.6 25.5 0.0 25.1 17.1 17.8 3.6 16.8 9.5 11.5 1.8 29.9 15.9 16.0 21.3 26.5 0.8 24.9 38.5 10.6 19.7 9.1 52.2 1.5 20.3 12.0 2.8 12.2 9.1 4.2 8.1 8.9 9.1 3.8 0.1 26.3 25.9 25.3 7.7 22.4 26.1 11.2 17.6 28.2 14.4 13.5 14.2 0.6 59.8 23.6 5.7 12.6 29.6 4.2 1.9 70.4 1.5 22.4 1.4 2.8 1.5 6.9 2.0 2.0 6.1 5.8 2.6 2.5 5.4 11.5 8.2 0.3 3.0 0.7 1.4 5.1 1.8 37.0 35.8 43.4 43.8 38.6 33.3 34.3 28.9 33.6 22.5 32.0 35.4 2.0 3.2 2.7 23.2 6.4 7.4 18.1 14.8 9.1 40.2 9.6 5.8 1.9 32.9 11.1 18.4 12.5 24.2 2.2 14.2 0.0 16.1 3.2 3.3 7.6 2.1 10.8 1.7 60.9 5.6 12.3 14.0 23.4 4.5 2.5 9.0 1.4 12.1 4.5 40.4 58.0 15.2 38.7 3.2 4.4 1.8 12.5 3.2 10.6 17.8 2.8 9.7 4.1 31.2 25.5 6.3 17.8 7.9 1.9 9.3 11.9 6.1 7.2 19.3 6.6 16.0 9.4 13.9 15.5 5.7 4.3 16.8 7.2 17.0 17.9 13.9 GIMAP2 "DKFZp586D0824, HIMAP2, IAN12, IMAP2" ENSG00000106560 "GTPase, IMAP family member 2" Q9UG22 7 150685697-150693641 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 45.0;Kupffer cells: 132.3;monocytes: 74.4;NK-cells: 96.8;T-cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 62.7;JURKAT: 34.9;MOLT-4: 79.5;REH: 34.0;U-937: 32.4" "Not detected" "Not detected" "HPA013589, HPA014746" Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Lipid droplets" Nucleoplasm "HPA013589: AB_1849666, HPA014746: " "prognostic favorable (3.50e-4)" "unprognostic (4.73e-2)" "unprognostic (2.53e-1)" "unprognostic (3.56e-3)" "unprognostic (6.60e-2)" "unprognostic (6.64e-3)" "unprognostic (4.60e-2)" "unprognostic (5.97e-2)" "unprognostic (3.39e-2)" "unprognostic (3.91e-1)" "unprognostic (5.52e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.56e-2)" "unprognostic (3.08e-2)" 11.7 6.9 6.7 40.3 6.6 11.6 11.9 7.1 9.7 10.6 6.5 11.8 12.4 10.7 8.9 4.9 8.3 17.0 8.0 6.3 6.9 6.0 17.0 22.0 78.4 9.2 7.4 16.9 2.1 2.7 2.6 19.6 8.5 5.0 15.7 0.5 6.5 6.2 4.2 5.8 19.4 11.4 8.3 62.1 11.9 1.8 7.4 50.2 6.1 12.3 57.4 15.7 5.2 8.7 1.6 0.0 0.0 0.0 0.6 0.6 0.8 0.0 18.1 2.2 5.1 0.0 23.7 4.2 0.4 1.4 9.8 1.0 0.0 1.0 0.2 19.8 0.0 12.8 0.0 0.5 2.8 9.9 12.6 6.8 1.8 1.7 0.1 5.3 62.7 34.9 0.4 4.9 1.0 0.0 79.5 24.9 0.0 0.0 0.0 34.0 0.6 9.7 0.1 5.9 0.0 0.0 0.1 0.1 6.3 0.0 0.9 25.2 14.2 0.9 0.3 0.2 0.1 5.6 5.5 0.0 2.3 32.4 3.4 15.1 83.8 7.3 93.9 118.3 118.3 15.8 122.0 114.8 47.6 15.8 166.7 124.8 40.7 136.2 121.4 5.7 107.6 130.2 6.7 6.6 7.1 9.7 6.3 6.9 9.2 7.4 8.5 8.3 7.4 8.7 15.5 12.8 2.2 1.0 11.8 3.3 1.9 0.6 1.2 0.1 1.7 1.3 1.1 1.5 1.1 0.0 0.0 0.4 22.8 1.5 0.0 1.6 0.0 3.8 3.8 27.8 0.0 13.5 0.1 0.7 0.7 3.4 1.1 1.1 19.7 1.4 45.0 4.2 38.1 0.0 0.2 4.2 6.1 132.3 11.1 0.1 4.1 38.5 1.8 7.5 74.4 0.9 96.8 2.0 0.3 1.0 2.9 0.7 4.0 2.2 8.4 1.2 4.6 0.1 6.6 1.7 1.1 0.1 0.3 0.5 3.1 0.4 57.7 4.8 3.7 2.5 GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;esophagus: 195.4;vagina: 139.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Basal keratinocytes: 12.2;Basal respiratory cells: 15.6;Ionocytes: 12.2;Squamous epithelial cells: 31.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Cell line enriched" "Detected in some" 10 "RT4: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" 0.5 0.2 55.8 0.3 59.4 95.6 3.8 73.0 80.9 65.9 36.0 0.0 0.0 0.9 0.2 195.4 0.4 1.3 0.1 50.2 63.5 0.0 0.1 0.3 0.8 60.0 71.8 0.0 0.1 0.0 4.4 0.0 57.5 0.2 0.1 0.0 34.5 0.0 0.1 56.8 0.2 0.0 47.7 0.2 0.3 1.4 76.3 37.6 5.3 0.0 15.4 10.3 139.3 42.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 4.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 186.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 1.1 0.6 0.5 0.0 0.0 0.0 2.6 0.2 55.8 59.4 73.0 80.9 50.2 63.5 60.0 71.8 57.5 47.7 76.3 42.7 0.0 0.0 0.0 58.8 0.0 12.2 1.7 15.6 4.0 0.0 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 6.9 5.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 12.2 0.0 0.4 4.6 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.3 31.0 3.8 0.0 0.3 0.0 0.0 2.4 GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.0" "Group enriched" "Detected in many" 4 "Sertoli cells: 157.8;Smooth muscle cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071788 Uncertain "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Cell Junctions, Cytosol" "HPA071788: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" 9.5 0.7 3.1 3.6 2.8 0.8 5.2 10.1 3.8 9.2 5.5 28.6 1.6 24.7 2.9 2.7 5.3 5.4 11.8 2.3 1.4 2.2 0.7 7.2 2.7 2.1 2.9 2.2 1.4 3.4 0.6 40.0 2.6 8.9 2.9 1.0 1.1 18.6 4.6 2.0 5.3 32.7 1.3 0.7 7.6 8.8 4.0 1.6 6.7 5.9 2.0 11.4 6.1 3.0 44.5 21.9 62.0 18.9 8.3 10.6 20.5 50.3 36.6 50.0 52.6 12.4 24.7 0.5 2.3 46.4 69.9 10.1 29.2 13.7 70.8 0.5 19.8 0.4 12.1 1.6 3.8 0.3 1.7 8.8 1.6 37.0 11.8 20.4 17.1 9.6 1.8 0.5 31.4 0.4 6.7 4.3 29.5 0.1 16.2 39.5 73.8 0.3 11.4 16.8 10.2 21.5 4.6 0.5 16.2 41.3 10.9 8.0 12.3 43.8 39.3 22.2 38.9 0.4 11.3 32.5 15.9 0.3 40.7 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.2 0.2 1.0 0.5 0.1 0.2 0.1 0.1 3.1 2.8 10.1 3.8 2.3 1.4 2.1 2.9 2.6 1.3 4.0 3.0 11.7 0.0 0.0 0.7 0.2 2.0 1.7 0.5 0.0 3.4 0.6 1.4 25.1 0.0 0.2 1.8 2.1 0.5 0.4 0.1 0.0 1.5 1.5 1.4 14.9 19.5 0.0 0.0 8.1 0.0 2.6 6.3 0.0 3.0 0.0 9.4 4.2 0.3 1.5 13.5 1.4 0.0 0.0 0.3 4.2 0.3 1.5 1.2 3.6 1.0 0.6 0.2 0.0 0.0 0.3 0.6 0.0 2.2 0.0 1.4 0.0 0.3 0.2 0.9 157.8 4.8 101.1 15.6 28.4 0.6 3.0 0.5 0.8 7.8 0.1 1.3 GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731462 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.7;kidney: 107.7;liver: 79.2" "Cell type enhanced" "Detected in many" "Langerhans cells: 139.2;Macrophages: 133.4;Proximal enterocytes: 144.2;Proximal tubular cells: 161.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 178.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 178.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 37.4;Hep G2: 46.4" "Low region specificity" "Detected in all" HPA060687 Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" "HPA060687: AB_2684343" "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favorable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" 8.8 9.8 3.1 51.5 2.8 6.6 4.8 3.7 17.2 4.8 8.4 13.0 86.6 3.6 12.3 9.6 7.7 23.8 4.8 2.3 4.1 107.7 79.2 19.7 10.6 7.2 4.2 2.6 4.5 14.0 5.4 8.2 6.8 3.6 10.9 10.3 11.2 2.2 2.6 6.3 90.7 4.4 3.6 10.1 6.2 2.9 14.5 5.4 6.6 3.1 14.5 30.2 2.7 8.0 4.5 3.5 4.5 7.7 2.7 10.4 1.8 10.6 37.4 7.6 8.6 5.8 4.1 12.6 1.7 4.1 6.9 0.3 8.5 3.5 10.1 8.2 9.6 7.5 6.6 46.4 17.2 14.2 15.4 6.3 4.9 24.2 22.3 1.9 6.0 9.6 4.0 17.3 2.1 6.2 11.0 14.6 7.5 4.9 4.0 15.0 7.1 13.1 5.7 14.8 4.8 6.1 9.4 9.4 21.5 4.5 10.6 10.1 2.3 5.5 2.3 0.3 4.9 9.1 10.7 12.5 9.5 9.1 5.6 5.0 22.8 7.9 1.7 7.2 1.3 3.1 3.1 2.2 14.2 5.6 1.8 1.9 178.4 4.8 9.1 4.2 11.5 6.2 3.1 2.8 3.7 17.2 2.3 4.1 7.2 4.2 6.8 3.6 14.5 8.0 2.0 16.0 27.4 19.6 15.8 6.9 12.3 12.6 4.6 3.2 9.4 3.9 4.3 12.8 22.5 7.3 16.7 1.2 5.6 54.7 35.2 21.9 61.5 15.1 2.7 3.8 12.1 6.3 41.5 11.1 1.1 12.4 20.9 1.7 14.5 6.9 3.6 38.1 34.8 5.0 37.2 14.7 0.0 26.6 139.2 29.9 1.2 133.4 14.2 10.3 42.6 29.1 3.1 28.6 19.6 10.6 39.9 2.2 12.4 17.0 144.2 161.1 47.7 17.7 0.0 9.2 7.0 15.3 1.7 14.7 16.9 0.8 15.7 3.7 11.0 26.8 GK2 "GKP2, GKTA" ENSG00000196475 "Glycerol kinase 2" Q14410 4 79406361-79408228 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 306 "testis: 89.5" "Group enriched" "Detected in some" 92 "Early spermatids: 589.0;Late spermatids: 163.3;Spermatocytes: 194.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 40 "SCLC-21H: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060687 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA060687: AB_2684343" "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 89.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 589.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GK3P "GKP3, GKTB" ENSG00000229894 "Glycerol kinase 3 pseudogene" Q14409 4 165277812-165279679 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Distal tubular cells: 1.9;Excitatory neurons: 1.3;Microglial cells: 1.0;Oligodendrocyte precursor cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060687 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 11: Alveolar cells - Smell perception" "HPA060687: AB_2684343" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.17e-2)" "unprognostic (2.11e-2)" "unprognostic (3.94e-1)" "unprognostic (1.61e-1)" "unprognostic (2.04e-1)" "unprognostic (6.19e-2)" "unprognostic (6.99e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (4.56e-1)" "unprognostic (3.34e-4)" 0.0 0.0 0.1 0.0 0.9 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 1.2 1.8 0.0 0.2 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 192.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 160000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA014558: AB_2732409, HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favorable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 11.9 7.9 18.8 16.2 22.2 23.9 16.4 14.4 20.0 17.4 2.7 29.6 14.2 11.8 6.2 15.6 8.8 14.8 21.5 22.7 10.8 14.5 9.4 27.0 20.6 8.5 11.1 7.2 11.3 23.0 8.4 14.8 9.7 20.1 30.3 13.0 54.3 13.0 16.4 25.1 16.2 15.9 8.9 19.0 21.3 10.4 12.4 34.1 13.9 25.9 17.8 19.3 12.0 13.3 18.2 17.5 6.4 10.9 52.3 24.8 19.6 25.4 52.3 24.7 32.2 13.5 12.4 38.1 17.9 35.1 20.1 23.2 29.8 32.8 38.4 18.1 15.6 16.3 15.4 19.3 9.7 15.0 31.7 19.3 17.7 23.5 13.8 61.4 44.0 30.0 25.9 11.0 23.4 27.8 45.6 21.0 22.0 22.6 12.5 10.6 32.6 51.2 39.5 46.8 13.6 11.2 42.3 29.7 60.7 23.5 30.6 9.8 43.6 23.1 12.5 19.6 14.4 30.0 32.9 21.5 26.4 21.8 14.6 8.6 3.8 4.4 18.8 3.6 6.2 3.0 4.0 10.3 7.1 4.9 5.1 7.9 1.4 17.0 4.6 6.9 3.3 3.7 18.8 22.2 14.4 20.0 22.7 10.8 8.5 11.1 9.7 8.9 12.4 13.3 25.3 60.9 65.0 35.9 42.1 16.8 32.9 16.2 17.1 23.6 25.2 18.9 43.5 18.6 27.8 22.0 25.0 25.7 107.3 68.3 7.9 10.3 0.6 25.3 23.7 21.1 18.0 19.5 84.5 15.1 15.0 18.9 33.1 61.6 122.8 24.6 10.4 9.7 46.7 8.4 83.8 29.6 24.4 46.7 17.6 3.8 17.1 41.2 42.7 30.0 43.5 26.9 192.6 135.2 19.8 15.7 129.3 12.8 63.9 28.1 17.7 13.8 10.0 37.0 0.0 18.6 14.9 12.4 33.0 26.7 14.3 8.8 63.4 30.6 49.7 46.5 GOLT1B "CGI-141, GOT1, YMR292W" ENSG00000111711 "Golgi transport 1B" Q9Y3E0 12 21501781-21518408 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055909, HPA066383" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 5: NTERA-2 - Transcription" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Nucleoplasm "HPA055909: AB_2682967, HPA066383: AB_2685667" "unprognostic (1.22e-2)" "unprognostic (3.07e-3)" "unprognostic (1.84e-1)" "unprognostic (3.65e-1)" "unprognostic (3.45e-1)" "unprognostic (5.37e-3)" "prognostic unfavorable (1.99e-8)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.83e-10)" "unprognostic (3.13e-1)" "unprognostic (2.14e-1)" "unprognostic (6.78e-2)" "unprognostic (1.04e-1)" 17.5 22.1 12.7 16.9 14.1 25.8 18.5 13.4 18.9 18.0 12.7 13.4 10.6 14.6 15.6 13.6 12.5 13.9 14.8 13.9 15.1 15.5 18.8 17.6 15.0 13.2 14.6 10.9 21.6 11.9 19.0 29.0 13.8 16.1 14.8 14.1 16.1 13.2 15.5 12.9 11.3 17.7 13.9 12.4 14.2 10.6 14.7 11.2 15.9 11.8 14.1 17.8 12.2 16.3 31.2 30.0 28.5 36.5 56.5 83.2 46.1 126.5 48.2 40.4 63.3 45.4 48.1 19.4 29.8 66.6 71.0 30.1 23.4 27.2 69.5 29.4 22.8 29.7 19.6 32.8 61.0 37.0 36.8 44.2 50.1 44.9 85.6 67.7 35.8 24.4 18.6 21.1 59.2 30.7 17.3 62.1 75.7 27.8 23.5 14.0 65.0 39.4 32.2 18.7 7.2 23.1 49.0 20.6 70.4 90.2 28.2 39.4 40.6 46.5 49.5 57.1 67.2 20.3 45.9 51.8 63.6 35.5 64.2 48.0 26.6 20.8 22.1 31.4 26.6 22.7 25.8 24.4 27.0 25.9 23.3 23.8 7.2 21.6 29.4 29.4 28.0 27.6 12.7 14.1 13.4 18.9 13.9 15.1 13.2 14.6 13.8 13.9 14.7 16.3 23.4 9.6 15.6 15.0 38.9 46.7 23.4 42.7 27.3 27.6 20.4 11.2 18.9 22.8 36.8 16.5 10.4 29.0 34.9 13.8 27.4 31.6 3.4 10.9 26.3 28.7 13.1 22.9 70.4 33.4 72.4 45.7 15.3 21.7 21.5 10.3 16.8 23.2 41.0 18.5 49.3 31.7 38.7 23.6 65.1 5.2 17.4 35.4 53.4 14.0 26.0 17.5 18.6 25.1 25.4 38.6 15.4 19.9 75.8 49.0 8.7 21.7 18.2 7.7 13.1 24.6 39.3 23.7 32.4 22.8 63.9 64.0 39.1 9.6 14.6 44.9 GPAT3 "AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324" ENSG00000138678 "Glycerol-3-phosphate acyltransferase 3" Q53EU6 4 83535914-83605875 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 88.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 60.0;Early spermatids: 82.3;Macrophages: 60.5;Proximal enterocytes: 56.2;Proximal tubular cells: 67.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 182.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 157.6;GAMG: 116.4;HMC-1: 57.4;U-87 MG: 66.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029414 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "HPA029414: AB_10601562" "unprognostic (9.51e-2)" "unprognostic (1.43e-2)" "unprognostic (5.67e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-3)" "unprognostic (2.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (2.92e-1)" "prognostic favorable (2.71e-9)" "unprognostic (3.74e-1)" "unprognostic (3.45e-2)" "unprognostic (2.53e-3)" "prognostic unfavorable (8.21e-4)" 14.0 1.0 0.9 5.7 1.1 11.9 6.5 3.9 2.7 5.5 8.9 13.7 39.9 3.7 1.2 8.3 3.6 8.6 25.3 1.0 2.8 88.4 18.1 4.2 2.0 5.5 3.4 16.1 1.2 23.2 5.0 1.5 5.5 1.6 11.1 1.2 3.5 3.6 37.6 2.6 35.6 3.5 2.0 4.7 15.2 7.4 2.7 1.7 19.8 12.5 2.1 6.0 6.3 1.8 30.6 29.6 0.0 0.4 1.5 3.7 0.6 2.4 4.3 0.6 0.6 2.2 157.6 0.0 3.2 5.9 116.4 6.8 14.3 2.8 0.5 2.1 6.7 0.0 9.2 29.7 4.2 8.9 57.4 2.0 0.2 1.1 3.5 11.5 15.0 8.5 25.1 23.7 0.6 3.1 2.3 2.2 0.7 45.6 12.5 0.3 6.7 11.6 29.8 2.0 0.7 0.0 5.8 6.1 17.3 1.6 1.2 1.6 0.7 6.9 12.3 6.9 28.9 1.1 2.2 0.0 66.4 17.6 52.2 182.5 33.2 4.0 0.6 27.8 6.0 0.1 3.5 2.0 81.4 0.1 2.5 1.2 91.1 1.6 23.6 0.3 2.3 10.4 0.9 1.1 3.9 2.7 1.0 2.8 5.5 3.4 5.5 2.0 2.7 1.8 4.8 6.4 6.8 0.0 1.3 0.0 60.0 0.0 8.0 0.8 10.2 4.1 0.0 4.3 5.0 11.0 0.0 0.4 0.8 18.6 15.6 4.8 82.3 1.0 1.1 5.4 1.2 6.1 0.0 6.8 1.3 5.5 34.7 2.4 7.6 0.8 7.5 13.2 14.8 5.0 0.0 9.9 0.0 11.3 0.0 21.7 1.2 60.5 0.0 0.0 28.7 0.1 1.0 0.0 0.0 10.4 6.7 0.7 1.2 32.4 56.2 67.4 1.5 0.3 6.6 5.8 1.7 10.6 1.9 5.2 0.0 1.0 7.3 4.9 3.6 28.9 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" 23.6 33.6 13.5 28.0 15.3 28.4 42.4 29.7 17.6 24.7 25.0 21.3 19.7 28.6 12.8 16.3 21.0 23.1 20.4 13.4 15.0 30.1 32.7 23.9 22.3 16.2 16.5 23.0 23.1 40.5 16.2 27.2 15.6 18.3 21.7 15.4 25.4 20.3 57.6 18.4 19.0 33.2 15.4 21.2 26.8 24.2 15.7 22.1 20.0 39.9 27.4 24.6 18.8 16.8 39.0 42.4 49.7 38.9 53.1 64.1 43.7 82.7 70.8 61.4 63.6 28.7 76.1 53.8 56.6 68.7 75.4 22.0 58.7 37.3 78.8 58.0 32.4 63.0 49.0 26.5 31.0 6.8 87.1 40.6 26.9 64.0 23.0 52.5 64.1 52.7 47.9 61.5 63.4 16.5 60.0 17.3 53.1 71.3 22.5 34.7 49.8 29.2 36.4 57.5 32.4 44.7 32.2 43.9 89.1 56.5 60.9 42.4 47.0 63.0 43.8 73.0 62.6 33.0 47.9 58.7 51.9 36.9 63.1 16.0 17.0 7.8 12.5 15.9 11.6 8.6 9.6 12.6 21.0 9.9 8.5 8.5 3.8 5.8 14.3 8.0 9.7 13.8 13.5 15.3 29.7 17.6 13.4 15.0 16.2 16.5 15.6 15.4 15.7 16.8 20.0 3.2 31.2 0.0 14.5 0.0 13.2 0.0 11.4 16.9 50.2 19.6 0.0 27.1 13.6 11.0 10.4 33.9 18.4 10.8 3.9 41.3 40.6 14.1 19.4 21.7 17.0 21.5 0.0 39.8 42.5 13.1 27.0 29.2 2.5 21.2 18.2 62.4 27.1 15.2 0.0 14.2 0.0 28.1 0.0 58.7 12.8 31.7 0.0 0.0 31.2 11.8 9.2 0.0 0.0 44.9 11.3 10.5 23.9 27.7 13.3 28.2 5.8 15.1 6.6 20.3 11.6 4.3 14.8 10.1 0.0 40.4 16.7 23.0 11.1 18.2 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPM6A GPM6 ENSG00000150625 "Glycoprotein M6A" P51674 4 175632934-176002664 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "brain: 577.8;choroid plexus: 249.3;retina: 147.3" "Cell type enhanced" "Detected in many" "Astrocytes: 3712.4;Excitatory neurons: 833.0;Inhibitory neurons: 581.3;Muller glia cells: 459.6;Oligodendrocyte precursor cells: 1341.6" "Cancer enriched" "Detected in many" 107 "glioma: 110.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 34.8;naive B-cell: 16.6" "Lineage enriched" "Detected in many" 12 "B-cells: 34.8" "Group enriched" "Detected in some" 10 "AF22: 49.9;Daudi: 43.0;HAP1: 17.4;U-251 MG: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017338 Supported NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA017338: AB_1849933" "unprognostic (1.36e-4)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.34e-2)" "unprognostic (9.45e-2)" "unprognostic (1.34e-1)" "unprognostic (3.82e-5)" "unprognostic (2.24e-1)" "unprognostic (9.13e-3)" "unprognostic (1.06e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" "unprognostic (2.24e-2)" "unprognostic (3.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-3)" "unprognostic (2.60e-3)" 3.8 4.2 366.9 1.4 455.6 0.5 2.5 422.6 577.8 6.8 249.3 25.4 1.9 7.7 2.9 1.9 7.5 4.4 2.8 469.8 268.7 7.1 13.4 20.1 2.6 225.0 265.4 12.3 1.8 0.7 7.7 0.3 222.4 5.7 6.0 147.3 0.9 6.9 0.6 0.8 3.4 11.1 257.9 15.8 1.1 1.5 281.9 0.3 11.9 0.6 1.3 2.6 2.9 336.4 0.3 0.7 49.9 0.5 0.0 0.0 0.2 0.1 0.5 0.2 0.4 1.1 0.7 43.0 0.2 0.2 1.8 0.9 17.4 1.5 0.1 0.2 4.0 0.5 3.7 1.4 0.1 0.4 0.7 0.1 0.0 0.1 0.2 2.0 0.0 0.1 0.4 1.7 0.0 1.2 1.6 0.6 1.2 0.0 0.6 0.2 0.2 0.3 0.1 2.1 0.5 0.4 0.2 0.9 0.2 0.3 0.6 0.1 0.2 0.9 0.6 0.6 50.8 1.6 0.1 2.6 1.8 0.4 1.1 0.8 0.1 0.1 0.1 0.1 0.1 34.8 0.1 0.0 0.2 16.6 0.1 0.1 0.4 0.1 0.2 2.9 0.1 0.8 366.9 455.6 422.6 577.8 469.8 268.7 225.0 265.4 222.4 257.9 281.9 336.4 0.6 96.1 8.7 3712.4 9.6 1.8 5.3 0.0 0.0 220.3 0.2 0.1 0.7 1.5 0.6 0.0 14.6 0.0 0.0 0.1 1.9 0.0 11.7 0.4 0.1 29.0 0.0 5.3 833.0 0.2 0.2 2.4 0.0 0.2 0.0 0.2 116.0 2.1 0.3 124.5 581.3 0.0 0.0 4.4 0.4 3.6 3.4 1.6 0.0 208.0 0.0 459.6 0.0 1341.6 37.3 0.0 0.0 1.5 0.1 9.0 0.0 3.4 0.0 30.5 0.0 15.3 3.3 0.5 0.4 0.2 0.9 0.1 1.2 3.0 0.0 6.5 GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 743.2;choroid plexus: 180.7;retina: 207.7" "Cell type enhanced" "Detected in many" "Astrocytes: 633.3;Excitatory neurons: 361.3;Melanocytes: 357.5;Muller glia cells: 1722.4;Oligodendrocyte precursor cells: 408.1;Oligodendrocytes: 1476.6" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 220 "plasmacytoid DC: 77.7" "Lineage enriched" "Detected in single" 268 "dendritic cells: 77.7" "Cell line enhanced" "Detected in many" "AF22: 154.8;AN3-CA: 150.1;ASC TERT1: 74.2;HSkMC: 110.0;SK-MEL-30: 154.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" 7.5 9.3 418.4 6.0 518.8 1.1 26.4 540.4 521.1 27.1 180.7 33.8 5.0 6.3 12.1 11.5 6.5 5.9 15.8 447.8 463.6 7.7 1.1 16.8 2.8 596.3 459.3 4.4 3.2 0.6 17.2 1.3 580.5 21.8 7.8 207.7 14.8 35.2 2.5 13.9 9.2 5.4 533.4 14.5 11.7 3.5 419.9 0.8 5.0 7.5 1.9 9.1 19.7 743.2 0.4 0.4 154.8 150.1 41.6 74.2 0.4 0.9 6.9 0.1 0.0 0.4 0.5 0.7 0.3 0.0 0.6 1.3 7.6 0.8 0.0 0.6 25.2 0.4 10.0 0.4 1.5 0.5 0.9 110.0 0.9 0.0 1.9 0.6 0.0 3.0 0.4 6.8 1.5 0.6 3.4 0.7 48.5 0.1 2.5 2.0 13.7 23.9 0.0 0.5 7.8 4.4 0.8 4.4 154.4 41.9 0.7 3.6 0.3 1.0 1.3 0.3 2.0 0.5 0.3 0.3 1.4 0.3 12.4 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 77.7 0.1 0.7 418.4 518.8 540.4 521.1 447.8 463.6 596.3 459.3 580.5 533.4 419.9 743.2 13.8 0.0 5.1 633.3 15.8 33.0 22.7 5.9 6.8 74.4 37.1 47.1 1.3 1.5 7.8 22.0 87.6 5.0 50.7 3.0 0.0 5.4 1.5 45.8 32.7 12.5 1.2 5.3 361.3 3.7 3.7 54.2 0.0 30.4 4.5 19.7 10.8 0.4 1.2 26.9 144.0 5.0 8.2 1.9 33.5 3.2 24.2 3.7 357.5 40.3 4.6 1722.4 50.4 408.1 1476.6 2.3 6.0 32.0 7.3 26.5 6.1 1.1 11.0 151.4 46.0 137.7 43.6 9.6 13.3 7.0 17.0 13.7 20.5 8.6 3.2 14.8 GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737603 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" Vesicles "HPA041924: AB_10804122, HPA041951: AB_10795385, HPA063863: AB_2685135" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "prognostic favorable (1.04e-7)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (4.23e-2)" "unprognostic (3.01e-2)" "unprognostic (7.89e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.29e-9)" "unprognostic (8.68e-3)" "unprognostic (2.95e-2)" "unprognostic (4.96e-3)" "unprognostic (4.13e-3)" 29.9 45.2 26.9 18.8 29.3 26.2 32.7 29.7 27.2 36.8 29.9 39.9 32.9 31.6 31.6 39.6 40.1 32.2 22.5 24.2 29.4 42.1 34.4 32.4 23.2 28.9 28.1 34.5 46.7 49.0 23.2 22.2 27.5 34.4 28.1 27.8 57.5 40.2 18.4 31.2 36.6 26.3 27.7 33.3 35.8 25.5 29.1 23.5 41.3 20.5 27.8 31.0 32.9 27.8 33.5 35.9 21.7 42.6 83.0 44.8 24.4 25.6 77.0 34.7 36.7 22.2 37.5 15.8 46.4 52.4 41.6 28.1 24.7 53.3 17.8 64.1 28.4 25.7 37.7 29.6 81.3 16.7 33.7 48.7 100.2 33.5 67.2 45.9 41.3 37.9 26.4 102.7 35.6 23.3 29.5 24.0 15.6 60.2 31.5 23.7 24.7 61.0 72.7 32.6 0.2 23.4 25.9 41.8 38.7 18.4 39.9 40.0 34.4 19.7 12.5 63.2 27.6 66.2 39.3 11.4 68.0 52.9 21.7 79.3 116.1 123.0 82.6 109.7 75.2 48.2 65.2 70.4 84.6 49.9 45.9 52.8 178.4 80.9 130.5 30.0 81.2 132.7 26.9 29.3 29.7 27.2 24.2 29.4 28.9 28.1 27.5 27.7 29.1 27.8 40.8 9.6 14.5 12.7 26.3 26.5 43.7 107.4 21.1 28.3 42.7 33.0 8.0 45.8 59.7 36.8 22.9 58.7 31.1 76.4 37.2 87.7 38.0 30.8 23.6 32.7 21.7 6.9 5.4 110.1 37.2 27.4 39.3 44.1 26.0 15.0 40.7 26.7 57.1 21.9 6.0 57.6 81.4 30.3 46.7 94.9 23.6 42.4 30.2 5.6 50.3 46.0 42.2 7.5 9.6 83.3 83.7 18.4 27.8 29.1 121.2 55.0 39.8 43.0 39.5 22.2 26.4 34.3 19.9 27.2 31.8 58.6 38.9 28.3 47.1 36.1 GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 203.8" "Cell type enhanced" "Detected in all" "Early spermatids: 193.1;Late spermatids: 573.0;Spermatocytes: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" 20.6 32.6 54.4 16.4 50.9 13.7 19.6 49.4 63.8 24.5 42.5 22.6 12.2 23.6 12.6 28.9 22.3 15.0 29.1 52.8 44.3 34.0 33.9 19.4 14.9 55.3 50.5 18.7 16.2 23.2 26.5 15.6 56.2 29.1 7.5 11.8 23.7 14.8 16.8 22.5 19.5 10.4 45.9 24.5 27.4 203.8 56.2 10.6 30.8 15.9 12.8 26.7 21.4 48.2 22.0 50.2 18.6 49.5 34.9 19.9 69.6 25.5 24.3 31.0 18.4 38.0 31.6 22.7 42.4 24.1 51.9 44.3 28.8 17.1 9.7 73.0 27.9 22.7 53.7 22.5 21.6 15.0 40.9 24.8 25.0 27.5 19.0 20.8 16.3 28.4 20.6 56.2 19.1 56.9 16.8 40.5 22.5 20.4 49.9 31.0 18.0 37.5 20.0 30.3 27.2 32.6 30.0 44.6 30.6 21.4 46.0 6.3 23.1 69.1 46.8 53.3 18.7 41.9 84.9 20.5 50.0 12.3 44.9 1.9 2.8 5.1 2.3 2.5 2.9 2.7 2.0 1.7 3.0 3.8 2.1 1.8 14.0 1.9 2.1 3.0 1.6 1.4 54.4 50.9 49.4 63.8 52.8 44.3 55.3 50.5 56.2 45.9 56.2 48.2 13.0 3.2 11.2 12.7 15.0 14.4 18.5 21.8 19.4 14.1 16.2 13.3 5.3 20.0 13.7 12.9 12.5 49.6 9.5 26.2 15.6 39.0 193.1 14.4 14.8 15.8 16.2 14.7 9.3 26.6 69.7 13.4 15.3 10.0 2.5 10.3 11.4 10.8 23.2 20.2 9.0 16.8 14.2 15.4 14.5 573.0 19.3 11.5 14.2 6.5 16.4 38.9 11.3 4.5 11.2 30.8 14.6 16.1 13.4 26.7 31.5 19.6 18.6 9.1 26.3 8.7 14.1 175.0 55.9 16.9 15.2 119.6 10.8 16.6 15.1 23.3 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 58 "Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cell line enhanced" "Detected in some" "HeLa: 3.1;REH: 4.4;TIME: 4.3;U-2 OS: 1.7;U-2197: 2.0;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 9.8 1.1 9.1 3.4 6.3 0.1 7.9 4.7 9.7 3.6 3.5 23.8 1.5 14.8 1.4 2.4 5.3 2.1 19.8 6.4 5.5 3.0 2.6 9.3 1.1 7.2 7.5 1.8 2.2 0.0 0.7 1.2 7.2 5.5 0.1 0.1 2.0 0.0 7.5 3.4 6.0 0.0 6.4 7.5 5.8 0.9 7.7 0.1 3.8 0.2 0.0 8.8 5.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.2 0.1 0.0 4.3 0.0 1.7 2.0 2.6 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 6.3 4.7 9.7 6.4 5.5 7.2 7.5 7.2 6.4 7.7 8.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 58.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GRAMD4 "DIP, KIAA0767" ENSG00000075240 "GRAM domain containing 4" Q6IC98 22 46576012-46679790 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.2" "Cell type enhanced" "Detected in many" "Astrocytes: 45.1;Distal enterocytes: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (8.67e-3)" "unprognostic (1.78e-3)" "unprognostic (2.19e-2)" "unprognostic (8.11e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.04e-4)" "unprognostic (1.08e-1)" "unprognostic (7.07e-2)" "unprognostic (5.72e-2)" "unprognostic (1.44e-3)" "unprognostic (1.54e-2)" "unprognostic (4.11e-1)" "unprognostic (1.61e-2)" "unprognostic (2.73e-2)" "unprognostic (2.08e-1)" "unprognostic (5.38e-2)" "unprognostic (8.69e-2)" 15.1 52.1 15.1 17.4 15.9 22.6 11.9 9.3 20.2 11.5 11.9 40.6 34.6 7.5 9.9 24.2 16.1 20.5 45.0 15.6 11.9 18.6 168.2 19.6 17.6 11.6 11.6 10.8 17.6 10.0 24.1 10.5 12.0 14.1 26.6 9.1 17.8 7.1 23.8 45.3 36.0 9.1 11.2 16.0 28.0 7.4 11.8 23.5 20.3 11.9 26.6 9.4 13.2 13.8 12.6 14.2 16.3 20.9 21.4 12.5 16.8 9.5 5.9 3.8 4.8 5.1 19.6 45.9 15.9 10.7 11.1 26.2 10.0 5.2 5.8 12.2 11.3 15.4 10.9 12.2 17.4 96.9 60.0 8.4 12.2 3.0 6.8 13.4 5.3 34.6 29.4 30.3 5.4 22.0 56.4 51.0 8.9 28.2 6.6 25.3 2.5 30.2 7.4 14.6 11.6 32.3 10.2 20.3 37.1 18.7 19.8 33.8 8.3 4.9 9.7 6.6 6.3 6.2 21.5 24.3 10.9 37.4 43.1 1.2 1.4 1.0 0.6 0.9 0.3 1.0 0.5 0.4 2.0 0.3 0.4 0.2 0.5 3.9 0.4 2.4 1.9 0.8 15.1 15.9 9.3 20.2 15.6 11.9 11.6 11.6 12.0 11.2 11.8 13.8 17.7 16.0 18.4 45.1 5.9 8.2 3.6 7.6 6.8 5.0 7.1 10.8 19.3 8.6 4.1 3.7 0.0 3.7 9.5 56.1 0.0 4.7 0.3 13.4 7.2 7.5 20.8 3.8 21.6 6.7 2.2 4.7 8.2 10.6 7.0 5.4 2.5 23.0 14.0 3.3 18.2 20.7 6.1 10.1 14.7 1.1 4.7 12.0 7.2 11.2 10.9 12.2 3.1 13.6 5.9 7.9 18.9 5.7 8.6 5.0 34.5 3.0 5.1 1.7 0.0 3.4 5.3 1.2 3.8 8.2 10.4 3.4 7.0 5.9 22.8 3.7 GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 468.4;Horizontal cells: 198.5;Inhibitory neurons: 396.3;Oligodendrocyte precursor cells: 385.0" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 23.8;BJ hTERT+: 34.5;fHDF/TERT166: 45.9;U-2197: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" 0.8 10.3 20.0 0.3 25.3 0.1 1.4 1.3 31.6 6.7 0.0 0.7 0.3 2.1 3.6 0.4 1.5 1.2 2.0 29.0 4.0 2.5 7.7 0.3 0.5 1.9 3.4 4.1 1.7 0.0 1.0 0.4 1.4 1.7 0.8 17.8 0.2 1.9 0.2 0.5 0.5 1.9 4.5 0.1 2.0 0.7 6.4 0.2 0.2 0.1 0.8 0.6 2.8 20.9 0.0 0.0 0.0 0.0 2.2 0.4 0.0 23.8 34.5 0.4 0.9 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 6.6 0.0 15.1 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 25.3 1.3 31.6 29.0 4.0 1.9 3.4 1.4 4.5 6.4 20.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.8 0.6 13.6 0.2 0.0 1.6 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.1 0.3 8.7 0.3 0.0 0.0 468.4 0.2 0.1 6.4 1.1 0.2 0.0 0.1 0.4 6.1 0.1 198.5 396.3 0.0 0.0 0.0 1.5 0.3 9.3 0.2 1.8 14.0 0.0 1.9 0.0 385.0 67.6 0.3 0.0 4.1 0.0 0.4 0.0 6.2 0.1 3.8 0.0 0.2 4.5 0.0 0.1 0.0 1.0 0.1 0.1 0.7 0.0 0.0 GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 6.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Cone photoreceptor cells: 6.2;Excitatory neurons: 16.2;Spermatocytes: 3.5" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA027868: , HPA065166: AB_2685425" "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" 0.3 0.0 1.6 0.0 2.2 0.4 0.1 0.0 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.7 0.7 0.0 0.0 0.1 0.0 4.9 0.1 0.0 0.1 0.0 0.1 0.0 6.0 0.1 0.0 0.4 0.1 0.0 0.3 0.5 0.1 0.0 0.0 0.2 0.0 0.6 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.2 0.0 2.3 1.7 0.7 4.9 0.1 6.0 0.0 0.4 0.3 0.4 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 2.6 0.5 0.9 1.1 0.0 0.0 0.0 6.2 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.0 0.0 16.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.4 0.0 1.0 0.8 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.0 0.0 0.2 0.1 3.5 1.1 0.2 0.3 0.0 0.1 0.2 0.0 0.1 GSG1L "KTSR5831, MGC18079, PRO19651" ENSG00000169181 "GSG1 like" Q6UXU4 16 27787528-28063714 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.5;heart muscle: 23.0" "Group enriched" "Detected in some" 7 "Excitatory neurons: 26.0;Oligodendrocyte precursor cells: 89.5" "Cancer enriched" "Detected in some" 7 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HMC-1: 8.3;THP-1: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014479 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014479: AB_2247974" "unprognostic (1.85e-1)" "unprognostic (2.41e-1)" "unprognostic (2.38e-1)" "unprognostic (7.06e-4)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" "unprognostic (2.05e-2)" "unprognostic (6.68e-2)" "unprognostic (5.02e-2)" "unprognostic (1.25e-1)" "unprognostic (2.50e-1)" "unprognostic (6.66e-2)" "unprognostic (1.55e-1)" "unprognostic (3.13e-1)" "unprognostic (6.35e-2)" "unprognostic (9.77e-2)" 0.2 0.2 15.6 0.1 19.4 0.2 0.1 9.4 19.5 0.2 4.4 0.4 0.3 0.3 0.3 0.1 1.5 0.0 23.0 17.9 11.0 0.3 0.4 0.4 0.1 21.8 20.0 0.1 0.1 0.0 0.5 0.9 19.0 0.2 0.1 2.4 0.2 0.1 0.3 0.8 0.4 0.0 12.5 0.3 1.1 1.6 22.5 0.0 0.3 0.0 0.0 0.4 0.1 11.8 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.3 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.2 0.0 3.2 0.7 0.0 0.5 0.0 0.1 0.6 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.6 19.4 9.4 19.5 17.9 11.0 21.8 20.0 19.0 12.5 22.5 11.8 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.1 8.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.8 7.4 0.1 0.0 0.0 26.0 0.0 0.0 1.8 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.7 7.4 0.4 0.0 0.0 0.0 3.6 0.0 0.1 0.0 4.7 0.0 0.2 0.0 89.5 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.7 0.3 0.5 1.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 GSTCD FLJ13273 ENSG00000138780 "Glutathione S-transferase C-terminal domain containing" Q8NEC7 4 105708778-105847725 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.2;Late spermatids: 52.4;Oligodendrocyte precursor cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046160, HPA061782" Approved Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA046160: AB_10961048, HPA061782: AB_2797265" "unprognostic (4.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.06e-3)" "unprognostic (4.44e-3)" "unprognostic (6.44e-2)" "unprognostic (6.43e-2)" "unprognostic (1.84e-3)" "unprognostic (4.30e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-2)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (8.59e-2)" "unprognostic (2.68e-1)" "unprognostic (1.32e-2)" "unprognostic (7.02e-2)" 2.6 2.4 1.7 3.8 2.1 5.3 5.5 3.8 2.1 3.6 5.7 3.7 2.6 3.6 2.7 5.0 4.3 3.6 2.3 1.6 2.0 4.4 2.5 2.6 4.6 2.0 2.3 2.9 3.2 3.5 2.3 3.7 2.0 3.9 4.0 7.3 2.2 3.5 2.1 3.3 3.0 4.1 1.7 2.8 3.3 10.8 1.9 4.7 5.3 2.7 5.2 2.4 2.2 3.2 11.2 10.0 22.2 19.5 5.8 7.4 16.6 15.5 7.9 18.6 16.6 9.2 21.0 13.2 7.7 6.5 10.8 8.9 25.8 16.0 26.3 19.9 7.2 10.7 9.5 12.6 2.5 20.7 7.4 4.0 8.0 17.2 13.1 7.0 11.6 13.2 22.0 11.7 16.0 9.1 21.9 7.7 12.2 16.4 11.5 14.9 13.1 7.4 20.4 8.0 18.0 8.1 11.9 17.2 6.6 19.5 15.3 8.3 8.8 13.8 14.4 8.6 12.2 4.4 10.1 7.4 8.6 10.4 19.4 0.7 0.8 0.4 0.9 1.1 1.0 1.0 0.8 0.3 1.0 1.1 0.9 1.5 5.5 1.4 1.4 1.3 0.1 0.7 1.7 2.1 3.8 2.1 1.6 2.0 2.0 2.3 2.0 1.7 1.9 3.2 5.8 6.4 3.9 32.7 5.2 2.5 3.6 2.4 2.2 22.3 10.4 4.8 3.3 8.6 1.9 9.2 27.1 6.1 2.6 5.6 3.9 5.8 120.2 7.7 8.1 4.6 4.2 12.8 32.0 5.0 8.1 5.0 6.6 9.9 2.5 9.3 3.6 8.0 7.7 21.9 32.2 4.4 2.0 5.1 3.1 52.4 8.4 4.2 5.4 9.4 4.2 7.3 3.1 53.8 35.4 6.8 1.3 4.5 7.1 3.8 1.7 5.0 2.4 21.4 0.0 5.4 4.9 11.2 7.5 6.4 4.3 3.3 2.9 6.3 6.1 2.0 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 68.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.4;Enteroendocrine cells: 176.7;Intestinal goblet cells: 56.0;Paneth cells: 97.9;Proximal enterocytes: 81.5;Undifferentiated cells: 47.6" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 1.4;CACO-2: 1.1;CAPAN-2: 1.7;SiHa: 1.6" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.5 0.2 0.1 3.4 0.3 0.5 0.0 0.2 0.1 0.0 3.0 37.2 68.2 0.3 0.0 1.9 0.0 0.9 2.2 0.2 0.3 0.4 0.3 0.2 0.4 0.4 0.3 0.0 2.2 0.0 0.0 0.2 0.4 0.3 41.4 0.1 0.6 0.0 0.7 1.0 66.5 1.4 0.5 0.2 1.9 0.4 0.3 0.0 0.5 0.0 0.3 0.5 0.2 0.5 0.4 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 1.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.1 0.2 0.3 0.4 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.0 1.3 6.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.0 0.0 0.1 0.1 0.0 0.0 176.7 0.0 1.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 56.0 0.0 0.3 0.3 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 1.0 0.2 0.4 97.9 0.0 0.1 0.0 81.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 47.6 0.0 HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 249.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" 68.3 11.2 16.2 16.5 23.5 8.7 22.8 19.3 20.5 14.6 8.4 26.7 29.9 16.6 17.7 18.9 13.1 16.7 10.7 16.0 19.7 24.1 48.4 19.4 21.3 19.4 17.1 12.5 17.4 21.3 7.7 15.5 21.0 29.5 27.7 13.8 16.4 12.9 5.3 32.5 25.8 16.7 17.8 12.3 21.2 19.0 16.6 14.9 19.4 8.4 28.6 14.7 17.1 33.9 76.9 42.7 28.8 21.1 88.3 19.5 106.5 53.7 22.2 54.6 39.4 87.9 66.1 44.1 37.8 51.7 63.3 162.8 52.3 67.4 57.3 28.3 17.5 30.8 37.3 68.9 28.7 41.2 29.4 27.2 169.7 26.5 73.6 85.2 29.0 30.0 6.3 42.7 33.4 59.8 19.7 12.3 37.2 92.7 37.4 29.6 31.6 46.9 66.5 48.6 50.5 15.8 249.9 52.7 34.6 41.5 54.9 21.1 22.7 56.8 42.2 57.5 53.1 25.2 34.7 35.9 25.5 28.5 31.1 0.7 1.6 1.1 1.5 1.2 2.2 1.5 1.9 1.9 2.8 2.0 1.8 1.7 0.5 1.3 1.0 1.6 2.5 1.2 16.2 23.5 19.3 20.5 16.0 19.7 19.4 17.1 21.0 17.8 16.6 33.9 19.8 6.4 43.1 8.8 17.5 0.0 28.7 0.0 23.9 9.5 27.8 21.5 13.5 22.8 15.5 46.0 6.2 21.5 18.9 29.4 7.9 15.4 19.8 22.3 14.9 17.0 15.8 15.4 34.3 18.7 16.5 17.3 25.0 35.7 3.8 17.1 16.8 47.5 22.9 1.7 29.7 16.4 0.0 24.2 0.0 10.4 11.5 25.1 0.0 12.2 19.6 14.5 19.6 25.1 32.6 19.6 16.6 17.7 15.0 40.6 33.8 17.8 2.9 13.9 6.6 14.8 11.3 10.5 24.8 35.1 0.0 6.7 14.2 11.8 19.9 33.2 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.3;Basal prostatic cells: 51.6;Basal respiratory cells: 107.1;Suprabasal keratinocytes: 158.6;Urothelial cells: 115.5" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 52.5;PC-3: 270.5;RT4: 111.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.8 0.5 0.9 0.7 1.2 0.9 7.5 1.3 1.3 4.6 0.9 5.3 2.9 0.9 1.1 33.5 1.2 4.8 0.7 0.6 1.1 1.1 1.3 20.1 0.4 1.0 1.3 1.4 1.3 0.4 1.7 3.4 1.1 3.7 3.1 0.8 5.4 1.5 1.2 9.7 2.2 0.6 0.4 0.8 12.8 3.5 1.0 0.5 5.9 0.9 2.8 92.8 10.3 1.0 3.5 17.1 1.0 0.9 0.3 0.4 6.6 1.1 0.4 1.0 0.4 3.4 9.0 0.7 2.0 0.4 4.0 52.5 2.9 31.5 1.0 0.2 1.3 0.0 0.2 0.6 0.1 0.3 0.9 0.5 8.6 1.0 3.0 4.0 0.7 0.6 0.1 0.4 0.3 1.8 1.2 0.7 15.5 18.7 270.5 2.0 0.1 0.2 28.3 111.6 19.2 0.8 1.8 0.1 0.3 3.1 0.6 0.8 0.3 0.9 0.9 29.9 1.8 1.0 0.9 0.2 1.0 0.0 0.6 0.1 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.9 1.2 1.3 1.3 0.6 1.1 1.0 1.3 1.1 0.4 1.0 1.0 4.2 0.0 30.8 0.7 0.2 162.3 51.6 107.1 8.6 1.1 1.6 6.1 1.4 0.0 12.2 0.0 2.1 1.0 0.1 16.4 0.0 4.5 10.2 0.7 0.3 2.4 0.0 0.4 1.0 3.6 0.9 1.1 5.1 2.7 0.0 0.4 1.1 0.2 0.3 0.0 2.1 0.7 2.0 0.0 6.5 22.7 1.2 0.5 3.6 0.0 0.0 0.1 0.0 0.5 0.8 2.4 0.2 0.4 0.6 18.4 0.1 0.7 3.0 1.0 0.0 0.9 1.9 0.5 0.7 25.6 158.6 0.3 1.1 0.1 2.2 115.5 HEATR5A "C14orf125, DKFZP434I1735" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 120.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 120.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" 8.6 11.1 8.9 8.9 12.5 7.0 8.0 11.0 8.8 9.6 9.7 14.1 10.3 7.3 5.8 10.0 8.9 7.4 16.3 8.2 12.9 10.2 8.7 8.9 5.7 13.8 11.6 6.2 4.8 9.1 7.5 12.1 15.5 5.8 11.4 7.4 8.0 5.7 12.1 4.2 12.0 10.3 10.1 8.0 7.5 8.2 10.5 3.5 7.6 20.3 6.7 10.9 6.6 18.5 28.3 43.3 12.2 15.7 29.0 27.3 25.3 33.6 28.3 18.0 18.3 17.4 21.1 15.1 31.4 50.7 10.8 18.6 23.2 10.3 25.5 11.5 21.4 11.4 56.5 73.8 16.9 21.9 15.8 12.8 5.5 15.4 14.6 14.1 22.8 6.9 23.4 15.2 21.0 25.2 8.2 9.4 9.3 17.8 25.2 4.7 24.1 8.6 11.9 17.5 5.1 15.3 77.2 35.3 78.4 17.0 20.0 6.2 35.4 13.1 19.6 22.5 13.6 14.9 42.3 23.8 3.9 12.0 19.5 120.4 11.8 47.3 2.7 11.7 1.6 4.7 1.9 2.4 8.2 3.6 1.6 2.9 38.4 3.7 18.1 3.7 2.0 4.6 8.9 12.5 11.0 8.8 8.2 12.9 13.8 11.6 15.5 10.1 10.5 18.5 7.8 28.9 20.2 58.4 7.5 5.9 2.4 6.3 5.2 12.1 9.9 5.5 17.0 5.7 15.5 18.4 14.6 13.1 2.7 33.5 1.9 11.7 3.5 16.3 9.0 8.7 6.7 2.5 27.1 11.7 10.8 13.1 9.7 7.4 11.4 6.9 10.4 14.8 10.6 1.7 38.8 13.5 10.2 14.8 10.8 1.3 12.2 13.6 10.6 42.2 15.1 19.2 1.0 67.8 96.6 17.6 22.4 11.7 10.1 6.3 17.3 8.9 21.8 9.3 0.0 18.1 9.6 21.7 13.2 10.0 7.2 18.1 5.9 11.4 13.1 4.9 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Distal enterocytes: 211.0;Intestinal goblet cells: 95.6;Paneth cells: 96.9;Proximal enterocytes: 156.2;Undifferentiated cells: 72.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.5;HEL: 25.4;HSkMC: 36.0;K-562: 72.5;LHCN-M2: 28.5;SuSa: 68.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" 8.2 19.1 18.2 14.7 25.0 0.0 8.3 20.8 19.2 23.8 8.7 81.9 79.0 34.7 14.4 11.9 14.2 38.7 36.0 16.7 21.2 8.1 3.5 12.3 3.6 22.3 24.4 22.1 2.3 1.4 3.7 1.3 20.4 24.3 77.6 15.0 7.6 31.8 0.8 4.8 81.6 82.7 18.8 11.1 12.4 3.5 21.7 1.3 5.1 3.2 2.6 19.5 10.1 21.0 0.0 0.0 28.5 2.3 0.0 0.1 0.8 7.3 0.4 0.0 0.0 17.4 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 25.4 0.0 0.0 0.3 0.2 0.1 36.0 0.0 0.0 0.0 9.9 0.0 0.0 72.5 0.6 28.5 0.0 0.0 0.6 14.1 4.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 68.6 0.0 0.0 0.7 16.2 1.2 0.1 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 25.0 20.8 19.2 16.7 21.2 22.3 24.4 20.4 18.8 21.7 21.0 2.5 0.0 0.0 78.0 0.5 0.9 0.0 0.0 0.0 1.0 0.9 6.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 211.0 0.0 0.3 0.6 1.3 15.1 4.1 40.8 0.0 0.3 1.1 0.0 12.6 0.0 1.2 0.0 1.1 6.4 0.0 0.2 0.0 2.9 95.6 0.0 0.0 1.9 1.5 11.5 0.3 0.0 6.5 0.0 26.1 0.0 3.5 36.2 5.0 96.9 29.7 0.0 0.3 156.2 0.0 0.7 1.3 6.6 4.4 9.8 0.0 0.3 0.3 0.6 0.0 0.5 6.9 72.4 0.2 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HHATL "C3orf3, GUP1, KIAA1173, MBOAT3, MSTP002, OACT3" ENSG00000010282 "Hedgehog acyltransferase like" Q9HCP6 3 42692663-42702824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 241.1;heart muscle: 521.2;skeletal muscle: 282.3;tongue: 154.2" "Group enriched" "Detected in some" 8 "Astrocytes: 59.1;Bipolar cells: 119.6;Cardiomyocytes: 65.2;Muller glia cells: 49.9;Oligodendrocytes: 168.0" "Cancer enhanced" "Detected in many" "melanoma: 14.2;thyroid cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA018174 Enhanced NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA018174: AB_2116671" "unprognostic (1.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.20e-2)" "unprognostic (9.71e-2)" "unprognostic (7.94e-3)" "unprognostic (3.79e-2)" "unprognostic (8.80e-2)" "unprognostic (2.47e-1)" "unprognostic (5.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (9.68e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-1)" "unprognostic (3.14e-1)" 0.5 0.7 77.5 0.0 163.6 0.0 1.3 124.7 110.1 0.5 34.3 0.3 0.0 0.9 0.4 4.0 1.8 0.4 521.2 76.0 109.5 0.3 0.3 0.7 0.3 152.8 152.1 0.1 1.3 2.9 3.8 0.1 149.3 1.7 0.1 37.8 10.7 0.2 282.3 1.3 0.2 0.2 101.0 0.2 0.2 1.1 127.8 2.2 21.4 154.2 0.1 0.1 0.3 241.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.5 163.6 124.7 110.1 76.0 109.5 152.8 152.1 149.3 101.0 127.8 241.1 0.0 0.0 0.0 59.1 0.0 0.4 0.0 0.0 0.0 119.6 0.0 0.0 65.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.1 1.2 0.0 0.0 4.8 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 11.1 0.0 0.0 0.0 0.7 0.2 0.0 0.0 5.4 2.8 0.0 49.9 0.0 1.5 168.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.2 0.0 5.5 0.5 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HIGD1A "DKFZP564K247, HIG1, RCF1A" ENSG00000181061 "HIG1 hypoxia inducible domain family member 1A" Q9Y241 3 42782908-42804490 "Predicted membrane proteins" "Electron transport, Respiratory chain, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 638.8;Distal tubular cells: 632.0;Paneth cells: 610.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 509.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043336 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA043336: AB_10795039" "unprognostic (6.46e-2)" "unprognostic (3.72e-3)" "prognostic favorable (2.12e-4)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (3.53e-1)" "unprognostic (3.70e-1)" "unprognostic (8.45e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-1)" "unprognostic (1.24e-1)" "unprognostic (8.94e-2)" "prognostic favorable (3.99e-8)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" 121.3 130.0 134.6 75.3 140.6 53.8 81.4 151.4 198.8 90.2 135.4 295.2 162.2 65.9 95.2 162.8 62.6 79.3 323.1 139.4 155.1 198.9 343.5 66.5 50.9 148.1 148.8 39.4 60.8 111.4 90.5 64.6 153.5 101.5 300.1 152.7 75.1 96.3 174.2 68.8 134.8 96.2 156.1 48.9 145.9 63.7 145.6 52.8 115.5 316.7 80.0 99.5 120.1 174.0 159.9 67.0 182.9 165.2 420.3 244.3 195.2 205.1 151.0 168.4 165.8 132.8 166.7 95.8 120.5 161.8 114.0 92.9 143.0 203.0 225.6 135.5 145.9 301.0 127.6 257.4 191.8 180.4 131.4 274.0 233.7 129.0 181.4 94.7 159.8 135.1 299.7 110.3 247.3 51.1 96.1 61.1 162.7 133.7 176.5 80.9 138.0 72.1 454.1 361.1 82.7 108.2 187.6 142.0 207.0 182.9 145.0 130.0 166.1 127.4 105.2 341.1 219.1 89.7 184.1 207.2 165.2 185.7 100.6 115.7 66.2 130.5 72.9 115.4 65.8 56.6 71.5 73.6 77.2 43.6 60.3 70.5 70.0 65.6 143.2 509.4 99.4 171.5 134.6 140.6 151.4 198.8 139.4 155.1 148.1 148.8 153.5 156.1 145.6 174.0 50.1 54.5 82.4 32.3 39.7 131.2 153.1 244.8 59.2 35.7 86.4 62.0 351.5 80.1 133.0 138.0 10.4 114.1 99.5 638.8 632.0 113.3 8.4 87.3 41.2 50.8 82.0 126.8 32.8 145.0 202.7 98.1 100.9 63.6 93.3 49.7 59.6 197.9 77.1 28.6 27.3 193.5 343.8 46.9 113.3 13.0 30.7 63.4 176.1 21.5 82.7 232.5 43.3 14.1 32.9 279.4 610.7 52.3 65.5 193.5 122.4 296.4 106.0 41.2 78.9 28.8 119.8 186.1 78.7 94.2 204.6 299.9 50.7 101.5 168.0 254.2 HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.6;choroid plexus: 65.0;placenta: 105.2" "Group enriched" "Detected in some" 5 "Sertoli cells: 762.6;Smooth muscle cells: 209.3" "Cancer enhanced" "Detected in all" "glioma: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (6.85e-2)" "unprognostic (9.41e-2)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-3)" "unprognostic (3.61e-1)" "unprognostic (1.18e-2)" "unprognostic (3.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-3)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.52e-2)" 11.7 0.5 71.0 0.7 71.0 0.5 8.8 70.3 114.6 8.3 65.0 3.7 2.1 9.9 11.6 5.0 5.3 11.3 46.4 68.8 71.4 11.5 0.6 38.6 2.6 71.4 70.9 2.9 3.1 8.0 1.4 105.2 72.4 9.5 1.1 2.3 1.4 6.4 14.5 2.0 4.3 11.3 68.9 0.1 3.7 1.5 73.0 1.8 5.0 30.8 1.4 4.3 4.4 69.1 0.2 0.6 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.3 0.2 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.1 0.8 0.5 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.7 0.5 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.8 0.4 1.0 0.0 0.5 0.7 0.3 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.6 0.2 0.4 0.5 0.4 1.2 0.6 0.5 1.1 0.7 1.7 0.6 0.2 1.2 1.0 0.4 0.2 0.7 0.9 1.2 0.3 0.9 0.7 0.0 0.7 0.1 0.3 0.8 0.5 71.0 71.0 70.3 114.6 68.8 71.4 71.4 70.9 72.4 68.9 73.0 69.1 88.9 0.0 0.5 0.0 0.3 3.4 0.6 0.3 0.0 0.5 1.2 2.8 11.0 0.0 1.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.7 70.2 0.0 0.0 0.7 0.0 0.2 4.4 0.0 0.3 0.0 0.0 0.7 0.1 0.8 1.7 0.6 0.0 0.0 0.0 3.9 0.6 0.3 1.6 0.0 2.8 0.0 1.0 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 762.6 9.5 209.3 0.0 0.3 0.7 2.4 0.3 0.8 32.3 0.0 0.7 HIGD1C Gm921 ENSG00000214511 "HIG1 hypoxia inducible domain family member 1C" A8MV81 12 50953922-50970506 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Early spermatids: 8.2;Excitatory neurons: 3.3;Inhibitory neurons: 4.0;Oligodendrocyte precursor cells: 7.1;Oligodendrocytes: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Karpas-707: 1.6" "Region enriched" "Detected in single" 10 "hypothalamus: 1.0" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.81e-1)" "unprognostic (3.10e-1)" "unprognostic (1.01e-1)" "unprognostic (4.21e-1)" "unprognostic (2.70e-1)" "unprognostic (5.49e-1)" "unprognostic (2.99e-1)" 0.4 0.3 0.3 0.0 1.1 0.0 0.1 2.9 1.2 0.3 0.6 0.2 0.0 0.2 0.0 0.1 0.5 0.5 0.0 0.4 0.4 0.2 1.1 0.6 0.7 0.9 0.8 0.4 1.0 0.5 0.1 0.0 1.0 0.1 0.3 0.2 0.4 0.2 0.3 0.6 0.3 0.3 0.3 0.3 0.5 1.7 0.7 0.4 1.0 0.2 0.3 0.3 0.0 2.1 0.0 0.0 0.1 0.5 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.1 2.9 1.2 0.4 0.4 0.9 0.8 1.0 0.3 0.7 2.1 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 1.9 0.0 0.0 0.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HIGD2B HIGD2BP ENSG00000175202 "HIG1 hypoxia inducible domain family member 2B" Q4VC39 15 72675798-72686182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.6" "Group enriched" "Detected in some" 10 "Early spermatids: 18.3;Late spermatids: 8.6;Spermatocytes: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019016, HPA042715" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Cytosol "HPA019016: AB_1850711, HPA042715: AB_2678127" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.24e-3)" "unprognostic (5.09e-2)" "unprognostic (3.34e-1)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "unprognostic (1.39e-1)" "unprognostic (6.98e-2)" "unprognostic (3.90e-1)" "unprognostic (8.80e-2)" "unprognostic (6.11e-4)" "unprognostic (6.95e-2)" "unprognostic (2.97e-1)" "unprognostic (1.11e-2)" "unprognostic (3.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 18.3 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 8.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.1 0.0 20.1 1.5 0.0 0.1 0.1 0.1 0.0 0.1 0.2 HLA-F ENSG00000204642 "Major histocompatibility complex, class I, F" P30511 6 29722775-29738528 "Plasma proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 220.4;NK-cells: 339.8;Proximal enterocytes: 298.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "A-431: 36.3;GAMG: 13.5;HEK 293: 12.5;HEL: 8.9;HHSteC: 10.1;JURKAT: 7.6;U-266/70: 8.5;U-937: 13.6" NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.07e-3)" "unprognostic (5.16e-2)" "unprognostic (3.05e-1)" "unprognostic (9.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (4.99e-2)" "unprognostic (2.68e-1)" "unprognostic (4.21e-3)" "unprognostic (2.43e-3)" "unprognostic (3.21e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (1.26e-1)" "unprognostic (2.95e-2)" "unprognostic (4.13e-2)" "unprognostic (1.30e-2)" 58.0 36.6 1.3 1.9 1.6 1.8 52.2 1.0 2.0 43.4 1.1 60.4 28.8 41.2 2.3 21.0 38.1 18.7 40.0 1.0 1.2 35.6 29.9 91.8 41.4 1.6 1.3 19.8 14.4 0.2 25.7 1.1 1.5 31.5 2.7 1.0 28.1 2.2 14.7 40.8 101.4 0.3 1.4 188.3 36.2 7.3 1.2 1.9 40.6 0.0 10.2 30.0 38.5 1.6 36.3 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.1 13.5 1.4 0.0 1.3 0.0 0.8 12.5 8.9 0.4 0.1 10.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 7.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.4 2.3 0.0 0.0 0.1 0.0 0.5 1.7 0.0 0.0 0.6 0.1 0.1 1.2 0.2 8.5 1.9 0.1 0.0 13.6 0.1 54.3 16.8 42.8 34.9 21.6 25.9 19.4 22.8 28.5 1.1 16.9 21.5 21.2 31.9 32.7 32.0 6.5 25.1 15.2 1.3 1.6 1.0 2.0 1.0 1.2 1.6 1.3 1.5 1.4 1.2 1.6 180.1 38.5 64.7 2.6 133.4 40.9 32.7 58.4 12.5 1.5 19.9 17.0 12.2 50.1 37.0 7.3 2.1 0.4 220.4 214.3 1.9 75.9 2.2 8.6 13.9 110.6 22.8 29.9 2.7 87.8 0.8 27.3 69.8 14.2 50.0 3.4 71.7 30.4 55.3 0.0 6.2 119.2 69.2 96.9 50.3 1.4 28.3 99.4 28.4 12.2 207.1 4.6 339.8 4.5 0.7 71.4 122.0 21.1 92.3 41.8 298.8 4.9 34.3 1.3 46.0 20.7 36.2 10.0 3.9 11.4 37.5 0.3 198.9 24.9 90.8 62.5 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 60.9 65.4 42.0 31.4 50.4 25.1 48.8 58.1 63.0 51.3 71.5 65.8 67.3 37.4 50.6 36.3 41.3 35.6 69.5 42.0 54.3 91.3 122.9 51.4 28.5 58.8 52.1 45.3 43.5 134.3 28.5 41.6 58.9 52.8 59.5 47.0 46.9 41.5 27.8 30.0 41.7 48.6 52.8 34.8 56.1 33.5 48.9 22.3 66.8 51.6 32.3 31.4 26.8 61.9 40.2 64.3 68.4 69.6 226.8 211.5 45.0 96.7 97.8 67.3 73.0 75.7 80.7 97.4 69.4 91.5 111.7 151.6 48.7 125.5 82.6 19.0 89.2 46.4 28.3 66.2 114.6 132.3 125.4 131.1 93.6 68.1 193.6 85.9 96.1 60.4 43.9 157.9 59.4 22.9 38.6 63.1 126.0 49.9 45.3 63.9 102.3 110.8 129.5 95.9 24.5 56.5 132.0 110.7 100.2 64.6 80.2 112.5 92.4 73.9 28.3 189.3 117.6 81.6 110.3 58.3 78.5 25.0 55.4 8.8 13.4 7.0 12.1 14.8 13.5 12.7 9.6 10.5 21.3 15.2 15.6 13.9 11.2 16.4 8.2 18.4 6.2 11.6 42.0 50.4 58.1 63.0 42.0 54.3 58.8 52.1 58.9 52.8 48.9 61.9 73.6 64.1 111.1 96.6 45.4 31.7 47.1 92.8 57.5 77.1 46.1 36.4 80.7 74.4 81.4 51.5 77.2 60.4 30.6 82.2 27.4 100.2 61.8 36.9 47.5 70.9 138.2 40.8 126.9 82.3 42.1 59.7 60.6 37.0 155.9 37.3 76.1 214.0 63.5 121.1 155.6 75.5 87.5 50.9 43.7 24.1 34.2 45.3 39.2 59.0 37.2 128.2 30.9 128.7 97.5 71.4 62.5 56.8 61.4 61.3 54.2 50.1 75.8 67.8 78.9 45.4 60.2 17.5 14.5 66.0 45.7 74.8 29.4 95.5 115.5 48.6 HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 45.4;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Vesicles, Intermediate filaments" "HPA045745: AB_2679440" "unprognostic (2.16e-1)" "unprognostic (4.32e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-3)" "unprognostic (3.66e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.25e-2)" "unprognostic (7.43e-2)" "unprognostic (3.39e-2)" "unprognostic (6.42e-2)" "unprognostic (3.66e-1)" "prognostic favorable (4.20e-7)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" 7.5 15.4 14.3 7.1 14.6 4.4 11.9 10.9 13.0 10.6 10.7 7.4 6.2 13.2 10.5 7.8 12.6 7.1 15.7 14.0 18.3 10.8 5.1 9.1 9.0 15.0 14.8 22.0 4.9 15.1 11.9 9.1 18.6 9.8 6.9 34.3 7.3 11.1 20.7 8.0 5.7 10.8 9.5 8.0 6.4 13.2 17.0 14.1 26.8 30.5 9.2 7.3 7.1 10.2 11.1 12.6 57.4 19.8 20.7 14.5 14.6 13.8 13.1 17.0 8.9 14.5 18.8 22.7 24.7 12.4 18.8 7.6 31.1 12.1 26.9 4.9 18.9 10.9 7.9 32.5 21.0 17.1 19.2 11.0 20.0 24.1 15.4 21.9 20.9 30.6 23.0 28.2 34.3 27.3 37.8 17.4 29.5 6.4 13.3 36.7 20.4 8.4 16.6 12.0 27.1 20.2 35.0 5.6 39.0 28.5 34.4 10.2 17.5 19.2 22.9 13.9 11.3 44.1 38.1 36.9 22.8 12.3 18.2 21.2 5.0 11.1 3.8 3.4 5.0 5.0 4.1 4.6 2.8 7.5 5.3 5.6 5.5 4.3 6.3 0.0 5.4 4.4 14.3 14.6 10.9 13.0 14.0 18.3 15.0 14.8 18.6 9.5 17.0 10.2 8.9 12.8 16.4 7.8 8.2 4.8 4.6 6.4 8.6 20.2 10.2 8.3 16.7 1.5 8.6 3.7 14.6 6.9 4.4 3.7 5.9 7.9 38.5 11.4 10.5 7.7 9.5 5.7 12.4 6.7 6.6 7.7 3.6 11.0 1.3 38.6 9.3 4.1 12.2 45.4 15.8 3.7 4.1 6.9 3.5 12.2 5.9 10.4 5.4 11.2 6.1 28.4 5.2 15.6 13.0 6.8 2.5 10.1 10.1 5.2 3.9 8.0 13.7 44.2 0.0 8.0 7.8 35.8 30.1 8.8 7.0 8.8 6.6 12.7 4.5 4.8 HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.2;choroid plexus: 5.6" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;ASC TERT1: 4.6;BEWO: 1.4;HEL: 1.5;U-138 MG: 2.3;U-2 OS: 1.4;U-87 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" 0.9 0.3 6.7 0.8 9.7 0.1 0.5 0.0 15.2 0.6 5.6 0.5 0.4 0.5 0.0 0.5 0.3 1.6 0.7 11.8 8.7 0.1 0.1 0.3 0.0 0.5 1.4 0.3 0.0 0.0 0.2 0.0 2.9 0.2 0.6 0.8 0.0 0.6 0.3 0.1 0.4 2.6 0.1 0.0 0.2 0.6 1.6 0.7 0.1 0.6 0.2 0.8 0.5 5.8 0.0 0.0 0.0 0.0 1.8 4.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 6.7 9.7 0.0 15.2 11.8 8.7 0.5 1.4 2.9 0.1 1.6 5.8 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 8.6 0.1 0.0 0.0 81.7 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.0 10.1 0.0 0.0 0.3 0.0 2.2 0.9 1.9 0.0 3.7 0.0 4.6 0.0 2.5 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 1.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IFITM10 DSPA3 ENSG00000244242 "Interferon induced transmembrane protein 10" A6NMD0 11 1732406-1750595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 2.6;bone marrow: 1.5;brain: 3.2;choroid plexus: 1.8;retina: 1.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 46.0;Bipolar cells: 30.5;granulocytes: 28.5;Hepatic stellate cells: 40.0;Oligodendrocyte precursor cells: 39.7;Respiratory ciliated cells: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.9;hTERT-RPE1: 4.7;MCF7: 4.4;SH-SY5Y: 11.2;SK-MEL-30: 4.0;U-87 MG: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.89e-3)" "unprognostic (2.10e-2)" "unprognostic (1.22e-6)" "unprognostic (6.49e-3)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" "unprognostic (3.66e-1)" "unprognostic (4.09e-1)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-1)" "unprognostic (2.44e-2)" "unprognostic (3.76e-2)" 0.1 2.6 2.1 0.1 2.1 1.5 0.0 3.2 3.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.2 2.4 0.1 0.3 0.2 0.0 2.3 2.2 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 1.5 0.3 0.5 0.2 0.4 0.1 0.0 2.1 0.1 0.0 0.3 2.3 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.2 4.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 11.2 0.0 0.0 4.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.1 3.2 3.0 2.2 2.4 2.3 2.2 2.4 2.1 2.3 2.2 0.3 3.2 0.6 1.0 1.3 2.2 9.3 46.0 14.2 30.5 0.8 1.7 1.9 1.5 16.4 0.0 0.0 1.8 0.4 8.1 1.9 3.9 0.4 1.2 0.5 1.0 0.0 0.0 10.5 2.6 0.6 5.4 1.1 2.7 28.5 0.0 40.0 1.6 20.6 1.7 11.4 0.9 18.3 5.0 1.1 0.6 0.9 9.3 0.0 1.9 2.6 2.1 3.1 39.7 1.0 2.3 4.2 1.5 1.3 1.3 3.3 0.1 49.4 2.3 0.0 2.4 4.0 0.5 1.3 3.2 0.9 2.6 2.5 0.1 1.9 12.7 IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 920.0;NK-cells: 1350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23410.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23410.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 424.6;HHSteC: 547.7;HMC-1: 494.9;HSkMC: 710.9;NB-4: 603.3;U-937: 485.2" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 450000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Cell Junctions" Nucleoplasm "HPA004337: AB_1851427, HPA044731: " "unprognostic (2.39e-2)" "unprognostic (2.69e-2)" "unprognostic (4.54e-1)" "unprognostic (1.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.87e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.37e-9)" "unprognostic (2.79e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" 1086.2 307.0 90.3 258.0 90.2 177.0 681.0 89.6 116.6 785.6 101.4 358.6 40.9 702.8 52.1 237.2 903.8 97.4 619.6 92.0 97.9 703.1 1288.5 1069.9 99.9 94.4 89.4 650.1 211.1 112.0 200.6 145.3 94.9 406.1 41.8 27.0 228.9 102.5 195.9 236.7 305.6 200.4 92.8 1402.1 304.3 123.0 95.4 29.8 437.7 132.8 105.8 493.1 496.6 95.1 32.2 65.4 313.1 2.9 137.2 358.3 0.9 106.8 65.1 27.0 63.3 1.7 206.9 2.7 126.6 424.6 0.4 68.5 1.1 9.3 9.0 1.8 41.1 75.1 102.6 117.6 547.7 124.1 494.9 710.9 2.3 5.2 3.3 64.4 51.2 22.5 5.2 210.5 11.6 129.9 2.5 603.3 36.4 5.3 229.4 101.0 29.9 1.1 181.6 0.4 0.8 7.0 65.4 74.9 34.5 5.3 86.7 69.8 338.3 5.7 26.8 36.1 1.4 4.5 5.0 3.3 14.5 485.2 18.1 2706.4 537.4 3789.5 666.6 1421.9 480.8 846.9 590.1 639.5 612.5 799.2 511.7 510.3 23410.9 1225.0 2199.0 279.0 411.7 1376.6 90.3 90.2 89.6 116.6 92.0 97.9 94.4 89.4 94.9 92.8 95.4 95.1 920.0 307.7 540.0 5.9 301.1 104.4 251.1 161.4 215.1 0.3 59.7 66.5 51.8 154.4 209.2 248.3 0.0 8.3 814.7 22.5 487.2 433.0 7.8 67.1 468.6 828.4 9.6 100.7 0.0 256.7 16.9 515.8 30.5 78.5 530.5 68.8 752.1 684.1 223.4 0.0 0.0 39.4 24.4 372.8 255.9 31.5 507.6 645.9 209.9 12.2 177.3 80.5 1350.1 0.0 0.1 161.9 149.2 223.8 123.0 126.3 4.7 45.3 104.8 1.5 315.5 442.5 568.4 8.4 10.4 22.8 83.0 23.4 667.2 61.8 44.3 102.4 IFITM3 "1-8U, DSPA2b" ENSG00000142089 "Interferon induced transmembrane protein 3" Q01628 11 319676-329475 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 2128.0;Endothelial cells: 2064.8;Hepatocytes: 2268.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2907.6;non-classical monocyte: 3344.3" "Group enriched" "Detected in all" 6 "granulocytes: 2907.6;monocytes: 3344.3;NK-cells: 926.2" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 3222.7;BJ hTERT+ SV40 Large T+ RasG12V: 4076.3;HHSteC: 3609.8;HSkMC: 3476.2" HPA004337 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA004337: AB_1851427" "unprognostic (4.17e-2)" "unprognostic (4.19e-1)" "unprognostic (1.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.55e-3)" "unprognostic (6.00e-2)" "unprognostic (3.36e-2)" "unprognostic (6.44e-2)" "unprognostic (8.90e-2)" "unprognostic (9.42e-2)" "unprognostic (7.45e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (5.78e-7)" "unprognostic (7.81e-2)" "unprognostic (3.34e-2)" "unprognostic (8.28e-2)" "unprognostic (1.19e-1)" 1850.7 745.9 639.0 597.4 667.4 237.0 1281.1 644.9 909.9 1683.7 730.9 1212.1 235.2 1545.6 840.1 484.5 1933.7 702.4 1199.6 643.2 732.4 1299.5 2506.4 1573.4 272.7 745.4 671.4 1262.3 576.3 637.2 493.2 829.2 697.9 885.6 238.9 92.6 555.3 631.7 364.5 511.2 599.9 1121.8 666.2 1241.8 736.0 266.7 728.7 229.3 935.7 426.0 154.9 1203.7 1038.2 649.0 554.1 49.6 1930.0 508.9 952.4 1538.6 44.2 842.4 1638.0 3222.7 4076.3 65.4 1818.6 1.3 873.1 1276.4 826.0 872.0 1.1 619.9 176.8 19.2 57.1 8.1 578.4 570.2 3609.8 5.7 5.2 3476.2 136.1 257.3 561.7 418.1 610.5 5.2 3.1 5.0 290.3 1095.0 2.7 26.3 243.0 2.2 425.3 74.2 185.3 4.8 1741.5 50.1 1.5 3.5 1007.5 170.0 891.9 259.0 41.3 39.7 1130.9 192.1 131.9 180.6 34.8 2.5 3.4 10.3 89.6 7.6 315.3 520.4 740.1 563.7 115.7 2745.9 69.0 82.2 82.6 118.9 396.9 55.6 77.8 109.0 2907.6 926.2 3344.3 31.1 52.9 921.0 639.0 667.4 644.9 909.9 643.2 732.4 745.4 671.4 697.9 666.2 728.7 649.0 1971.3 532.0 709.5 32.0 35.5 317.2 684.3 856.2 1237.9 1.2 207.9 253.1 157.4 539.1 562.1 527.8 2.1 122.2 68.6 94.4 559.6 2128.0 27.3 164.2 1197.8 2064.8 54.1 92.0 0.0 1898.5 635.5 1572.4 103.5 207.0 242.7 223.5 2002.5 2268.4 539.7 0.0 0.1 228.2 132.2 491.4 463.2 102.3 1861.8 713.0 361.1 39.4 130.7 162.4 62.8 0.0 0.5 1135.8 198.3 1060.7 18.7 416.9 54.1 563.8 260.3 7.8 959.8 953.3 1483.2 26.9 12.5 222.4 209.1 125.7 96.6 303.3 263.4 270.6 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33229901-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 211.2;U-266/70: 261.6;U-266/84: 145.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.00e-2)" "unprognostic (7.83e-3)" "unprognostic (4.98e-2)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-3)" "unprognostic (8.05e-2)" "unprognostic (4.17e-2)" "unprognostic (2.11e-2)" "unprognostic (7.65e-2)" "unprognostic (4.42e-1)" "prognostic unfavorable (7.54e-7)" "unprognostic (9.70e-3)" "unprognostic (2.39e-1)" "unprognostic (5.12e-3)" "unprognostic (1.85e-2)" 21.3 9.0 13.2 33.2 13.6 29.1 16.4 11.5 14.8 12.7 9.7 16.7 17.4 11.7 8.2 8.0 11.7 21.0 13.4 11.0 14.3 14.3 28.7 22.6 33.5 16.7 14.0 11.8 10.0 12.5 10.1 22.9 15.1 10.1 17.4 8.3 13.7 11.3 9.0 7.0 16.2 18.3 13.6 41.0 14.8 5.3 15.8 33.9 10.7 10.8 36.4 38.2 9.0 14.0 17.0 18.4 9.9 23.7 11.9 27.3 16.2 18.1 45.1 14.2 15.7 24.4 20.8 28.3 12.8 25.4 22.8 10.9 15.2 9.2 15.0 18.3 19.9 100.9 19.1 22.2 17.5 17.5 38.0 20.7 8.7 16.8 18.5 24.8 46.0 41.5 30.2 211.2 13.7 9.1 44.0 19.6 18.3 24.2 11.7 14.9 53.4 50.7 30.8 31.9 26.6 14.2 29.5 28.2 23.9 10.4 4.4 30.5 32.2 15.3 9.3 12.5 10.1 261.6 145.3 64.3 20.5 60.3 37.5 44.5 38.5 63.8 31.2 65.0 32.2 25.7 37.9 29.3 36.6 17.1 27.5 30.8 101.2 35.2 73.4 101.0 65.8 41.3 13.2 13.6 11.5 14.8 11.0 14.3 16.7 14.0 15.1 13.6 15.8 14.0 35.6 60.9 16.1 19.6 49.4 6.8 43.8 41.7 2.8 6.6 11.4 12.4 2.2 20.0 23.6 11.0 6.2 28.9 64.4 6.0 3.9 67.5 3.0 6.7 10.0 39.0 3.0 27.6 44.4 62.7 72.1 15.4 4.6 8.5 31.7 11.8 44.6 19.6 44.9 20.2 42.3 4.4 4.1 73.5 17.1 3.3 7.5 58.5 19.6 74.9 47.9 6.4 89.6 51.3 29.4 73.8 5.9 9.1 188.8 89.5 17.3 10.2 35.2 5.6 0.0 16.8 12.5 4.2 19.9 4.3 5.7 23.5 43.9 2.5 4.9 83.2 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IL23R IL-23R ENSG00000162594 "Interleukin 23 receptor" Q5VWK5 1 67138907-67259979 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.6;testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 11.1;Enteroendocrine cells: 3.0;Late spermatids: 6.0;T-cells: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 21.7" "Lineage enriched" "Detected in single" 29 "T-cells: 21.7" "Cell line enhanced" "Detected in some" "HL-60: 2.4;HMC-1: 9.1;K-562: 3.6;U-2197: 13.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056427 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA056427: AB_2683129" "unprognostic (4.01e-3)" "unprognostic (8.04e-2)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.16e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (8.64e-5)" "unprognostic (1.43e-1)" "unprognostic (3.02e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.9 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.4 1.5 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.4 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 13.8 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 21.7 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 11.1 0.2 0.1 0.1 3.0 0.0 0.3 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.2 6.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.1 0.2 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.3 0.0 4.2 0.0 0.4 0.2 IL9R CD129 ENSG00000124334 "Interleukin 9 receptor" Q01113 X 155997581-156010817 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4;urinary bladder: 4.4" "Group enriched" "Detected in some" 5 "granulocytes: 4.5;T-cells: 2.7" "Group enriched" "Detected in some" 4 "cervical cancer: 0.7;urothelial cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.4" "Group enriched" "Detected in many" 23 "B-cells: 1.8;granulocytes: 3.4;T-cells: 1.4" "Cell line enriched" "Detected in some" 10 "HMC-1: 247.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA063240, HPA064557" Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA063240: AB_2732700, HPA064557: AB_2732716" "unprognostic (1.07e-2)" "unprognostic (3.27e-3)" "unprognostic (9.52e-3)" "unprognostic (4.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.26e-4)" "unprognostic (8.94e-2)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (3.98e-8)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (4.07e-1)" "prognostic favorable (1.90e-7)" 0.1 0.0 0.2 1.0 0.2 0.5 0.2 0.0 0.2 0.2 0.0 0.5 0.6 0.2 0.1 0.5 0.3 0.8 0.0 0.1 0.1 0.1 0.2 1.0 2.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.9 0.1 0.4 0.1 0.1 0.4 1.7 0.1 0.1 1.7 0.7 0.0 0.1 3.4 0.3 0.0 2.2 4.4 0.2 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.5 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.3 23.8 0.0 0.0 0.0 0.5 247.8 0.0 0.2 0.0 0.0 0.0 0.0 5.6 3.7 0.8 0.0 1.1 9.5 4.9 0.0 0.1 0.0 0.6 0.1 0.0 0.0 19.2 0.2 0.1 0.0 0.4 0.2 0.0 0.3 0.4 0.0 0.1 0.6 0.1 0.1 1.2 0.6 0.9 0.2 0.3 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.8 0.3 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 4.5 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.5;Inhibitory neurons: 124.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 8.7 8.2 15.9 13.2 19.5 12.7 6.1 18.8 22.0 7.0 1.0 11.3 7.3 7.5 5.2 7.7 6.6 9.9 10.5 15.9 9.9 5.2 4.1 9.6 17.2 9.2 3.5 7.0 6.6 8.9 7.7 8.1 9.2 6.0 7.9 10.7 5.6 6.3 8.4 4.1 8.8 9.8 4.7 16.7 7.3 5.9 5.9 20.3 5.9 11.6 12.5 10.8 5.5 10.1 12.7 11.0 18.2 14.8 10.4 11.1 19.2 10.0 9.4 10.9 11.3 14.6 11.5 7.8 13.3 15.4 14.0 12.6 12.6 11.1 8.5 27.7 10.9 9.5 9.7 6.5 8.8 17.3 34.3 9.9 9.9 10.6 9.0 9.5 15.1 44.9 8.5 67.4 8.3 16.2 26.3 16.8 17.6 7.4 11.3 12.0 12.5 51.9 5.6 41.6 12.8 15.7 12.1 10.1 9.5 18.7 4.8 13.8 14.3 12.7 17.9 10.1 7.5 50.2 31.1 5.8 10.5 16.2 11.5 1.1 1.0 2.3 2.8 2.2 3.3 0.4 1.6 1.8 1.1 0.1 2.2 2.5 1.1 3.2 3.4 3.3 0.9 1.0 15.9 19.5 18.8 22.0 15.9 9.9 9.2 3.5 9.2 4.7 5.9 10.1 14.6 6.4 13.1 50.9 11.2 8.0 6.4 2.8 9.1 49.7 5.3 4.2 12.6 2.8 7.8 5.5 8.4 10.2 64.6 4.1 3.9 4.0 13.5 6.2 9.1 14.2 5.4 7.2 150.5 1.5 8.7 9.9 6.6 6.3 0.0 22.4 14.3 3.4 10.5 33.7 124.4 5.6 4.1 36.4 18.4 10.9 9.3 25.3 10.6 73.1 26.8 8.4 71.1 55.8 26.1 3.8 2.5 12.0 48.6 5.9 1.2 3.3 5.1 14.1 6.6 9.9 12.4 8.6 14.0 5.2 6.1 9.4 48.3 9.4 3.6 6.8 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.7;Early spermatids: 178.1;Excitatory neurons: 196.8;Inhibitory neurons: 614.4;Late spermatids: 291.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 150.4;SK-MEL-30: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 9.9 4.0 5.2 6.7 6.7 2.1 18.3 3.2 6.4 13.1 0.3 5.8 4.6 5.4 3.9 7.5 7.3 7.9 17.4 5.5 3.4 5.4 1.8 6.5 10.8 1.3 2.7 5.7 2.5 2.0 1.3 5.7 1.9 4.7 5.1 1.7 2.7 4.7 7.9 3.6 5.5 7.3 0.0 6.8 5.8 18.6 7.3 5.9 4.3 5.2 6.9 14.0 8.7 6.0 27.7 11.4 7.3 3.6 5.5 3.4 1.4 32.5 37.9 8.2 15.3 3.1 150.4 0.8 8.9 29.4 12.6 41.1 0.0 37.9 19.1 0.1 1.1 6.6 4.0 0.1 1.8 1.4 5.0 5.9 5.2 5.8 19.4 24.7 4.8 0.0 0.0 1.5 17.9 49.1 1.1 0.0 0.3 16.8 8.1 0.3 24.7 1.4 11.3 50.3 0.6 0.7 3.7 11.2 66.6 4.3 34.2 4.9 3.1 18.8 22.6 28.0 0.3 0.4 0.1 0.1 4.4 29.7 49.5 6.1 0.2 0.0 5.2 0.0 10.1 0.0 30.4 13.6 0.1 0.1 20.6 8.9 0.5 17.0 0.0 0.1 17.4 5.9 5.2 6.7 3.2 6.4 5.5 3.4 1.3 2.7 1.9 0.0 7.3 6.0 13.4 0.0 0.6 158.7 2.6 6.6 9.5 7.0 4.0 7.5 49.0 15.5 42.2 7.2 20.2 9.2 0.0 1.7 8.7 8.7 5.9 12.2 178.1 19.8 58.2 13.2 8.9 6.1 196.8 30.6 5.1 5.1 19.4 5.4 6.3 0.6 6.4 0.3 8.1 6.7 614.4 3.5 4.1 2.8 4.9 291.9 13.7 3.9 72.9 47.8 1.3 0.9 2.1 79.4 57.6 76.3 0.2 6.4 4.5 20.5 10.1 0.9 35.7 0.8 85.5 5.2 84.7 2.5 1.9 1.9 2.6 1.9 60.4 1.8 4.3 42.9 INTS1 "DKFZp586J0619, INT1, KIAA1440, NET28" ENSG00000164880 "Integrator complex subunit 1" Q8N201 7 1470277-1504389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021658, HPA053009" Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA021658: AB_1852402, HPA053009: AB_2682016" "unprognostic (3.20e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-2)" "unprognostic (2.08e-1)" "unprognostic (1.97e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (7.72e-3)" "unprognostic (3.11e-1)" "unprognostic (1.90e-2)" "prognostic favorable (4.83e-4)" "unprognostic (4.30e-1)" "unprognostic (5.10e-3)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (1.81e-3)" 19.4 20.3 11.1 13.2 9.2 25.7 20.2 3.2 16.8 23.8 2.2 24.5 14.9 23.4 2.0 21.6 23.9 8.0 23.6 10.5 2.9 23.0 23.5 19.9 15.6 11.2 6.5 28.0 31.2 9.0 25.1 9.5 6.2 24.9 4.1 4.7 21.3 10.0 56.0 23.8 24.0 5.4 2.9 26.6 22.8 47.9 8.2 22.4 25.8 11.6 6.3 22.3 19.5 8.8 63.9 54.4 20.8 54.2 15.0 11.5 72.3 26.5 14.6 20.1 17.6 60.3 48.3 34.1 27.2 19.1 40.4 64.6 11.8 31.5 5.6 16.7 64.8 24.3 80.3 40.5 17.4 42.6 35.0 15.5 14.6 20.7 14.5 12.0 22.1 47.5 68.8 26.5 12.4 77.1 24.2 115.9 114.0 23.3 48.2 60.4 23.6 34.9 9.6 47.7 39.2 96.4 38.1 68.8 24.1 11.9 54.7 42.2 41.3 32.8 92.8 27.6 44.1 55.0 31.6 33.6 36.8 36.2 68.7 2.0 0.9 1.0 1.4 0.6 0.9 0.8 1.1 1.2 1.2 2.7 0.6 0.9 0.7 1.0 0.6 0.6 1.5 0.8 11.1 9.2 3.2 16.8 10.5 2.9 11.2 6.5 6.2 2.9 8.2 8.8 16.5 12.8 25.8 19.9 14.0 5.9 4.9 11.1 9.6 34.7 20.7 17.4 52.0 14.3 11.5 11.0 25.0 12.9 14.6 44.6 0.0 16.3 23.2 21.4 15.2 18.3 18.0 5.9 22.4 23.6 13.3 15.8 30.1 27.4 1.3 43.6 15.4 26.3 15.0 48.8 14.5 23.4 12.2 19.8 8.1 41.4 13.4 12.8 5.4 12.2 12.6 14.9 7.2 12.5 11.0 19.9 21.7 15.4 17.9 9.1 28.8 12.9 13.7 36.1 26.3 16.6 15.7 20.8 11.6 13.3 8.0 15.2 12.2 23.5 29.3 6.1 INTS2 "INT2, KIAA1287" ENSG00000108506 "Integrator complex subunit 2" Q9H0H0 17 61865367-61928016 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049524 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "HPA049524: AB_2680804" "unprognostic (4.57e-3)" "unprognostic (2.11e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.72e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.52e-1)" "unprognostic (7.79e-2)" "unprognostic (5.91e-2)" "unprognostic (3.95e-1)" "unprognostic (1.85e-1)" "unprognostic (7.03e-2)" "unprognostic (1.81e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.42e-1)" 3.2 3.0 0.3 3.6 1.0 2.5 3.0 2.5 1.4 3.2 0.2 2.8 2.7 3.3 1.0 3.6 2.8 1.5 3.1 0.3 0.4 2.1 2.7 2.6 5.4 0.8 0.5 3.1 2.2 4.0 3.1 2.5 0.5 2.4 3.3 4.3 2.9 0.8 3.1 3.6 3.1 1.9 0.0 3.4 2.8 4.6 1.1 4.9 2.7 1.7 5.4 2.8 3.3 1.9 8.9 15.4 14.8 8.2 4.5 5.2 6.8 6.2 3.6 9.1 6.9 9.1 4.9 17.7 5.0 3.2 11.4 12.7 14.3 4.1 15.2 8.2 10.5 20.7 6.1 15.8 2.8 26.0 14.3 4.0 6.0 6.9 14.2 5.0 6.6 11.5 19.0 10.6 6.4 17.2 31.0 10.5 5.5 12.7 10.4 23.3 39.6 13.9 3.5 7.9 11.3 12.6 7.7 4.2 5.9 10.3 18.1 8.7 6.6 19.8 12.9 6.8 8.9 8.4 16.2 24.3 6.0 9.6 6.2 2.1 0.3 0.2 0.9 0.6 1.4 1.5 1.0 1.3 0.8 0.4 1.1 1.4 0.4 0.4 0.9 0.7 1.2 0.4 0.3 1.0 2.5 1.4 0.3 0.4 0.8 0.5 0.5 0.0 1.1 1.9 7.3 6.4 3.1 17.3 8.3 4.6 3.3 4.7 6.8 12.9 5.9 4.6 9.1 8.6 6.1 1.8 14.6 5.5 6.7 3.3 0.0 3.3 4.5 8.4 8.4 5.8 2.4 9.4 19.8 2.6 3.9 5.9 5.1 9.3 5.1 11.1 6.1 6.4 5.3 15.2 26.4 5.7 6.1 7.9 2.2 9.6 4.4 6.0 0.0 9.4 7.4 6.0 3.1 24.1 37.3 4.7 1.7 3.4 5.4 4.9 3.1 1.7 8.4 10.9 0.0 8.0 7.3 12.4 10.9 9.1 5.4 2.2 8.7 7.1 5.8 3.8 ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 10 "Early spermatids: 170.7;Late spermatids: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cell line enhanced" "Detected in many" "HEK 293: 30.9;HEL: 32.0;MOLT-4: 34.5;RPMI-8226: 33.0;U-698: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" 3.4 0.4 0.5 2.9 1.0 1.1 3.8 3.2 0.7 0.9 0.3 0.9 1.2 0.5 0.5 1.5 0.8 1.6 1.3 0.5 0.5 0.5 0.5 1.4 3.9 0.9 0.5 0.4 1.4 0.5 0.4 1.2 0.8 2.0 0.9 0.9 7.5 1.5 1.5 0.8 1.7 1.0 0.6 2.6 1.2 27.8 0.6 5.1 0.7 2.0 4.2 1.5 1.2 0.8 0.0 0.0 7.3 0.1 0.8 1.9 8.3 1.6 8.7 7.2 14.1 3.3 0.3 0.0 0.1 3.1 0.1 0.7 25.4 0.0 8.1 15.7 30.9 32.0 0.2 14.4 3.9 0.1 0.0 5.4 0.0 8.3 0.0 0.0 4.7 20.4 0.0 10.6 0.2 0.0 34.5 5.0 10.5 0.0 0.0 22.7 23.1 33.0 0.3 0.0 21.2 14.2 0.0 0.0 0.1 4.4 0.0 5.3 2.4 0.0 0.8 0.1 0.1 15.4 21.4 35.3 4.1 0.0 6.8 0.4 0.2 0.0 10.2 0.2 12.9 1.6 3.3 9.7 1.2 0.4 0.7 4.1 0.1 2.7 0.0 0.5 6.3 2.3 0.5 1.0 3.2 0.7 0.5 0.5 0.9 0.5 0.8 0.6 0.6 0.8 9.4 3.2 0.0 0.0 2.3 0.3 4.8 1.8 2.2 0.7 3.6 2.9 0.7 2.8 3.5 0.0 4.2 0.9 6.9 1.0 0.0 0.1 170.7 0.2 0.6 2.7 0.0 1.7 0.2 0.2 2.3 0.9 0.5 0.1 0.0 0.8 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 2.4 145.2 1.2 1.8 1.8 0.0 0.3 4.3 11.3 0.0 0.0 0.3 0.1 0.7 7.6 3.3 0.0 0.3 0.8 1.7 6.6 0.6 2.9 3.6 2.8 1.7 1.0 0.4 14.8 0.3 0.4 1.3 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 174.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA031172: AB_10670563, HPA071650: AB_2686429" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (4.95e-2)" "unprognostic (5.88e-2)" "unprognostic (2.54e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.09e-6)" "unprognostic (2.68e-1)" "unprognostic (3.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (3.14e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.73e-1)" 25.9 34.9 23.6 17.7 26.5 22.9 32.5 29.5 30.3 23.0 34.2 29.6 17.3 30.5 26.4 17.8 31.2 30.8 25.9 22.9 30.2 44.5 34.0 30.7 25.2 30.1 29.8 25.8 20.7 56.6 28.6 33.8 31.3 29.9 29.5 34.7 25.4 27.0 17.1 17.9 24.0 27.7 28.7 23.0 24.4 30.4 26.1 22.1 34.6 21.1 20.7 26.4 16.2 32.0 54.8 68.0 57.3 46.8 40.9 59.0 42.8 85.9 76.6 52.6 62.9 21.8 108.1 27.7 75.6 85.5 55.3 40.0 41.2 52.8 72.1 82.8 24.0 30.3 38.5 42.3 56.0 45.6 53.6 60.9 56.6 45.9 32.6 82.1 55.7 35.8 25.4 54.9 100.7 54.1 25.6 37.8 31.2 45.9 60.4 31.4 73.6 27.9 92.1 59.3 23.7 40.9 82.8 68.4 45.1 40.0 66.4 32.3 72.4 54.9 65.6 53.0 58.0 21.7 45.5 32.7 80.7 33.2 68.0 86.3 59.3 82.3 34.4 74.8 34.3 36.1 37.0 37.0 51.9 34.1 38.9 36.5 89.4 50.2 83.0 70.5 47.0 57.8 23.6 26.5 29.5 30.3 22.9 30.2 30.1 29.8 31.3 28.7 26.1 32.0 25.5 22.4 31.2 29.7 23.6 30.0 32.8 132.9 54.1 30.3 31.6 27.1 10.2 41.5 66.3 46.0 18.8 64.2 42.0 27.4 7.9 45.4 174.5 43.3 31.7 26.9 31.2 40.8 30.3 54.8 64.8 37.4 27.5 20.9 34.9 28.0 26.4 41.9 57.8 28.6 26.8 26.7 89.5 60.3 31.4 61.2 35.4 40.4 48.0 19.7 34.2 40.1 29.9 28.1 34.5 51.4 21.3 31.6 50.2 26.3 22.4 53.0 110.6 30.3 13.1 27.5 58.8 85.1 41.1 30.7 29.1 29.8 27.6 30.3 24.6 20.9 KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 81.3" "Group enriched" "Detected in some" 4 "Astrocytes: 49.9;Excitatory neurons: 36.7;Inhibitory neurons: 37.1;Muller glia cells: 19.8;Oligodendrocyte precursor cells: 36.2" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Region enhanced" "Detected in many" "cerebral cortex: 81.3" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "Karpas-707: 4.8;SCLC-21H: 1.4;U-2 OS: 1.2;U-266/70: 1.9;U-266/84: 3.1;WM-115: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" 1.3 0.3 5.0 0.7 7.4 0.0 0.6 11.1 81.3 0.2 0.0 1.6 0.4 0.1 0.3 0.4 0.1 0.3 0.7 4.5 12.5 0.1 0.0 0.1 0.6 28.0 7.5 0.1 0.8 0.0 2.1 0.0 32.0 0.5 0.5 9.6 0.5 0.8 1.0 0.5 0.6 0.4 0.1 0.3 0.7 0.9 27.1 3.0 2.3 2.1 1.5 0.3 0.3 20.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.9 3.1 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 5.0 7.4 11.1 81.3 4.5 12.5 28.0 7.5 32.0 0.1 27.1 20.7 0.1 0.0 0.0 49.9 0.2 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.5 0.2 0.0 0.0 36.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 37.1 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 8.4 0.0 19.8 0.0 36.2 6.8 0.0 0.0 5.3 1.6 0.0 0.0 0.0 0.0 4.2 0.0 0.4 1.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 47.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 79.6;Excitatory neurons: 48.2;Inhibitory neurons: 120.2" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.2;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "HeLa: 1.6;RH-30: 3.7;SCLC-21H: 3.5;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" 0.1 0.8 1.1 0.1 3.3 0.9 0.2 41.0 47.3 0.9 0.0 0.3 0.3 0.3 0.0 0.2 0.1 0.2 0.1 4.5 8.0 0.1 0.2 0.1 0.2 8.8 3.0 0.2 0.4 0.0 2.2 0.0 9.3 0.2 0.0 7.0 0.3 0.0 0.5 0.5 0.3 0.0 1.0 0.2 0.3 1.4 12.3 0.1 0.3 1.2 0.0 0.3 0.5 18.8 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.1 0.2 1.1 0.3 1.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.4 3.7 0.4 0.0 0.2 3.5 2.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 1.0 0.1 0.0 0.2 0.3 0.4 0.2 0.2 0.4 3.2 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.2 0.0 0.5 0.2 0.2 1.4 0.2 0.3 0.3 0.1 0.1 1.1 3.3 41.0 47.3 4.5 8.0 8.8 3.0 9.3 1.0 12.3 18.8 0.2 0.0 0.0 5.5 1.1 0.0 0.2 0.0 0.0 79.6 0.3 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 9.5 0.2 0.5 0.4 7.7 0.0 48.2 0.2 0.0 0.3 0.0 0.3 0.0 2.8 0.0 0.0 0.0 1.7 120.2 0.0 0.0 0.0 0.0 10.2 0.3 0.2 0.0 7.5 0.6 1.5 0.0 16.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.2 0.5 6.1 5.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 KCNJ1 "Kir1.1, ROMK1" ENSG00000151704 "Potassium inwardly rectifying channel subfamily J member 1" P48048 11 128836315-128867373 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Bartter syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 117 "kidney: 198.0" "Cell type enriched" "Detected in some" 5 "Distal tubular cells: 195.6" "Cancer enriched" "Detected in some" 7 "renal cancer: 3.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 39 "RPTEC TERT1: 116.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA026962 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA026962: AB_10601934" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-1)" "unprognostic (2.44e-2)" "unprognostic (6.47e-2)" "unprognostic (2.78e-1)" "unprognostic (6.05e-2)" "unprognostic (4.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (7.81e-3)" 0.2 0.1 1.0 0.1 1.6 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.5 0.1 198.0 0.1 0.2 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 116.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.1 0.3 0.5 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 38.6 0.0 0.0 0.1 0.0 195.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 KCNJ10 "Kir1.2, Kir4.1" ENSG00000177807 "Potassium inwardly rectifying channel subfamily J member 10" P78508 1 159998651-160070160 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 100.7;kidney: 28.0;retina: 36.7" "Group enriched" "Detected in some" 5 "Astrocytes: 93.0;Muller glia cells: 75.7;Oligodendrocyte precursor cells: 35.7;Oligodendrocytes: 93.7" "Cancer enriched" "Detected in some" 6 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.7;SK-MEL-30: 2.1;U-266/70: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078302 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "HPA078302: AB_2732378" "unprognostic (2.64e-2)" "unprognostic (3.54e-3)" "unprognostic (6.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (6.98e-4)" "unprognostic (1.96e-1)" "unprognostic (7.13e-2)" "unprognostic (3.43e-1)" "unprognostic (1.28e-3)" "unprognostic (5.80e-4)" "unprognostic (9.52e-2)" "unprognostic (2.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "unprognostic (6.70e-3)" 0.1 0.3 56.7 2.1 86.3 0.0 0.1 100.2 58.4 0.2 8.7 0.5 0.2 0.1 0.0 0.1 0.1 0.1 0.1 51.4 78.7 28.0 2.1 0.1 7.3 92.7 94.7 0.1 0.1 0.1 0.4 0.0 87.5 0.2 0.2 36.7 0.3 0.2 0.1 0.4 0.5 0.0 71.8 10.5 0.9 0.6 83.6 0.4 0.2 0.1 1.9 0.1 0.1 100.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.1 1.0 0.1 0.0 0.6 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 0.2 0.0 0.1 2.1 0.5 0.0 0.3 0.1 0.0 0.2 0.5 0.0 2.0 1.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 56.7 86.3 100.2 58.4 51.4 78.7 92.7 94.7 87.5 71.8 83.6 100.7 0.1 0.0 0.0 93.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 3.7 4.2 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 13.0 0.0 1.1 0.0 1.1 0.0 3.7 0.0 75.7 0.0 35.7 93.7 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 3.5 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNJ11 "BIR, Kir6.2" ENSG00000187486 "Potassium inwardly rectifying channel subfamily J member 11" Q14654 11 17385248-17389331 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 134.7;tongue: 40.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.1;Collecting duct cells: 5.5;Enteroendocrine cells: 4.2;Excitatory neurons: 5.5;Inhibitory neurons: 5.9;Oligodendrocyte precursor cells: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 6.6;HEK 293: 12.3;MCF7: 10.0;SCLC-21H: 8.5;U-266/84: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048891 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA048891: AB_2680547" "unprognostic (1.95e-2)" "unprognostic (6.18e-3)" "unprognostic (7.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (4.81e-5)" "unprognostic (1.83e-3)" "unprognostic (5.45e-2)" "unprognostic (8.09e-3)" "unprognostic (3.72e-3)" "unprognostic (9.23e-3)" "prognostic favorable (1.56e-4)" "unprognostic (4.05e-2)" "unprognostic (2.10e-2)" "unprognostic (1.67e-1)" "unprognostic (4.75e-2)" 2.7 0.6 5.1 0.4 8.3 0.2 3.0 12.4 11.9 0.6 0.0 1.1 1.0 0.9 1.6 1.5 0.7 0.5 13.8 5.3 4.2 4.7 1.5 2.5 0.8 8.0 3.4 0.3 11.3 5.0 7.4 0.1 8.2 2.2 0.4 1.3 2.2 2.4 134.7 1.5 1.3 0.1 2.6 1.6 13.1 0.6 6.4 0.3 5.1 40.7 0.5 0.9 0.4 5.9 1.5 2.1 0.2 4.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 2.0 0.2 6.6 0.2 0.0 0.3 0.3 4.1 0.1 0.2 1.6 12.3 3.4 0.9 0.5 0.1 0.5 0.3 0.1 0.2 0.0 0.1 0.1 0.0 5.6 3.5 3.6 0.0 10.0 0.7 0.1 1.1 4.0 0.3 1.3 1.6 2.0 0.3 0.9 8.5 0.7 0.0 3.4 0.0 0.0 4.2 0.2 0.0 0.0 1.1 0.0 0.0 0.2 6.5 0.8 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 8.3 12.4 11.9 5.3 4.2 8.0 3.4 8.2 2.6 6.4 5.9 1.5 0.0 2.7 3.3 0.1 0.0 0.1 0.0 0.0 2.1 2.6 0.9 14.1 0.0 0.6 5.5 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.3 0.3 4.2 0.0 5.5 0.4 0.0 0.9 0.0 0.6 0.0 0.2 0.4 1.3 0.1 0.0 5.9 0.9 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.0 0.8 0.1 0.0 0.0 0.0 0.8 0.1 0.2 0.0 0.7 0.0 1.3 0.2 0.2 0.3 1.0 0.0 0.0 0.0 0.1 0.4 0.2 KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 159.5;intestine: 91.3" "Group enriched" "Detected in some" 4 "Muller glia cells: 54.8;Proximal enterocytes: 217.4;Undifferentiated cells: 68.1" "Cancer enriched" "Detected in some" 5 "melanoma: 5.9" "Group enriched" "Detected in many" 4 "cerebellum: 7.3;hippocampal formation: 8.0;thalamus: 5.3;white matter: 3.4" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "U-2197: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nuclear membrane" "HPA051609: " "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "unprognostic (9.03e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (1.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" 0.1 0.1 0.4 0.0 1.3 0.4 0.1 7.3 1.1 0.1 159.5 0.1 7.9 0.1 0.3 0.1 0.0 2.2 0.1 8.0 0.4 3.3 0.2 0.1 0.2 1.3 0.8 0.2 0.8 15.8 0.2 0.0 1.3 0.1 0.0 13.7 0.2 1.1 0.1 3.2 91.3 0.1 0.4 0.1 2.3 0.5 5.3 0.1 7.0 0.0 0.0 0.1 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.3 0.0 0.2 0.2 0.1 0.0 1.9 0.3 0.3 0.3 0.0 0.4 0.2 0.6 0.2 0.1 0.3 0.7 0.3 0.3 0.4 0.4 0.3 1.0 0.0 0.4 1.3 7.3 1.1 8.0 0.4 1.3 0.8 1.3 0.4 5.3 3.4 0.1 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.5 0.5 0.0 0.0 1.8 0.0 0.0 0.2 0.1 1.9 0.0 3.0 0.7 0.3 0.2 0.0 0.0 1.1 1.3 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 25.7 0.0 0.0 0.0 0.6 0.0 0.1 21.4 0.0 0.0 54.8 0.0 1.5 2.0 0.0 8.8 0.0 0.0 0.1 217.4 0.2 0.0 1.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 68.1 0.0 KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 197.9;Cholangiocytes: 88.6;Proximal tubular cells: 236.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 68.7;GAMG: 103.6;HBEC3-KT: 69.6;RPTEC TERT1: 67.5;RT4: 80.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" 8.7 0.5 0.8 20.7 0.7 14.1 2.8 0.9 6.7 12.7 0.5 0.9 1.5 0.5 11.0 8.5 1.2 30.4 0.8 0.8 0.6 241.6 2.8 42.2 1.2 0.9 0.6 0.3 57.8 0.7 0.4 4.6 1.8 2.6 0.4 0.5 25.5 14.6 0.5 3.0 0.7 2.4 0.3 11.7 40.5 1.8 5.4 1.9 129.5 3.0 1.9 25.1 8.1 1.1 1.6 0.0 0.3 0.6 13.7 68.7 0.6 1.0 4.8 0.0 0.0 0.0 0.6 0.2 0.0 7.5 103.6 23.5 0.0 69.6 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.1 21.0 7.2 17.8 3.8 1.5 3.2 0.1 0.2 0.7 31.6 0.0 0.1 0.2 0.0 0.1 0.7 1.5 0.3 0.7 67.5 80.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.4 3.5 0.2 1.7 0.4 0.1 5.6 4.3 0.4 0.3 19.3 0.1 0.0 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.3 395.3 0.0 0.0 0.4 0.0 4.6 0.8 0.7 0.9 6.7 0.8 0.6 0.9 0.6 1.8 0.3 5.4 1.1 2.9 60.9 197.9 0.0 1.1 2.8 10.4 20.7 13.6 0.0 0.5 0.0 1.6 88.6 33.1 31.3 0.0 0.1 0.0 0.0 17.6 27.8 1.9 0.0 0.0 4.6 0.0 0.0 0.3 8.6 0.8 1.5 15.8 0.1 6.3 0.0 0.7 0.4 0.4 0.0 0.1 0.0 2.0 2.9 3.0 2.2 0.6 5.9 1.8 0.0 2.1 0.0 0.0 0.0 0.1 44.7 0.0 0.0 0.1 0.7 0.0 236.9 7.0 0.0 0.0 1.5 0.8 1.1 1.1 16.8 1.6 0.1 1.7 0.1 0.0 9.0 KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 196.1;parathyroid gland: 269.2;thyroid gland: 139.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.3;Collecting duct cells: 244.6;Distal tubular cells: 41.1;Oligodendrocyte precursor cells: 54.8;Proximal tubular cells: 95.2" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 279.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" 0.3 0.4 10.0 0.4 14.0 0.6 3.8 22.7 11.6 0.1 2.3 0.6 0.7 0.5 15.9 0.3 5.1 18.8 0.6 6.8 39.5 196.1 1.3 0.9 0.8 39.7 37.6 0.2 44.2 269.2 1.0 0.9 25.7 0.2 0.2 1.2 11.8 21.7 0.3 0.8 2.5 0.0 29.9 1.5 23.4 1.7 27.3 0.2 139.4 0.0 0.1 0.0 0.0 20.8 0.1 0.4 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.2 1.2 0.8 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 12.7 0.0 0.0 279.8 0.2 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.2 0.8 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.3 0.3 0.1 0.0 0.3 0.2 0.2 1.6 0.3 0.0 0.1 0.3 0.1 10.0 14.0 22.7 11.6 6.8 39.5 39.7 37.6 25.7 29.9 27.3 20.8 0.1 0.0 0.0 12.1 0.0 0.0 0.0 2.7 0.0 0.0 2.3 1.1 0.4 54.3 2.6 244.6 0.0 0.0 0.0 0.0 41.1 12.4 0.0 2.8 0.1 0.0 0.0 0.0 1.0 1.4 0.0 0.3 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 54.8 0.1 6.0 0.0 0.0 0.0 0.0 1.0 95.2 9.8 0.0 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 KCNJ2 "IRK1, Kir2.1, LQT7" ENSG00000123700 "Potassium inwardly rectifying channel subfamily J member 2" P63252 17 70168673-70180044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 42.9;parathyroid gland: 36.0" "Group enriched" "Detected in many" 4 "Horizontal cells: 240.6;Oligodendrocytes: 164.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 30.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 8.9;HUVEC TERT2: 6.3;REH: 7.5;RH-30: 29.2;U-138 MG: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029109 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 62: Horizontal cells - Visual perception" "HPA029109: AB_10602913" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (3.50e-1)" "unprognostic (6.36e-3)" "unprognostic (1.22e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.74e-3)" "unprognostic (6.15e-3)" "unprognostic (9.60e-3)" "unprognostic (4.89e-2)" "unprognostic (5.49e-3)" 1.9 0.8 7.2 5.1 19.5 1.9 4.9 13.4 13.1 0.9 0.0 3.9 0.9 0.9 0.6 2.9 6.6 1.4 9.8 5.9 11.8 1.0 1.3 2.1 1.3 18.6 16.2 0.7 0.4 36.0 0.6 6.3 18.2 1.8 3.2 7.6 1.3 1.8 9.7 4.7 1.4 1.0 10.5 7.3 0.8 0.3 14.5 1.8 1.2 8.4 1.5 1.9 1.8 42.9 0.0 0.9 1.8 0.0 1.9 0.5 0.0 0.6 4.5 0.1 0.1 0.0 0.0 0.0 0.4 0.5 1.2 0.5 0.1 0.3 0.1 0.0 0.2 0.0 0.6 0.0 5.4 0.0 0.0 2.0 0.1 2.8 0.3 8.9 6.3 0.0 0.0 0.0 1.9 0.0 0.7 0.0 0.2 0.8 0.2 7.5 29.2 0.0 0.7 0.0 0.4 0.8 0.5 0.1 0.0 3.5 0.3 0.5 0.1 10.6 0.1 0.1 2.4 0.0 0.0 0.1 2.3 0.0 1.5 4.2 3.5 5.6 0.0 6.9 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 30.4 0.0 7.3 0.2 0.0 0.8 7.2 19.5 13.4 13.1 5.9 11.8 18.6 16.2 18.2 10.5 14.5 42.9 12.0 0.0 3.2 0.0 0.6 8.2 4.1 4.9 16.5 43.5 5.8 9.3 19.3 0.0 1.9 1.8 0.0 0.5 0.1 13.5 0.0 0.1 0.3 2.3 0.2 16.0 10.7 0.4 3.8 0.0 0.4 1.7 4.1 1.6 0.0 0.1 3.3 0.1 6.8 240.6 16.2 2.7 0.0 36.9 7.4 0.0 1.5 7.8 3.6 2.8 8.2 5.8 0.0 1.5 164.7 0.0 12.3 1.2 0.0 2.2 0.9 0.1 4.9 5.2 0.0 3.9 2.6 0.1 0.9 6.9 3.3 1.4 0.8 0.2 8.5 0.3 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KCNJ4 "HIR, hIRK2, HRK1, IRK3, Kir2.3" ENSG00000168135 "Potassium inwardly rectifying channel subfamily J member 4" P48050 22 38426327-38455199 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 28.9;heart muscle: 33.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.3;Excitatory neurons: 14.3;Horizontal cells: 10.1;Inhibitory neurons: 11.1;Microglial cells: 3.7;Muller glia cells: 6.2" "Cancer enhanced" "Detected in some" "glioma: 2.1;liver cancer: 1.8" "Group enriched" "Detected in many" 5 "amygdala: 10.5;basal ganglia: 18.9;cerebral cortex: 28.9;hippocampal formation: 21.9;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 11.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 14 "amygdala: 5.9;basal ganglia: 13.7;cerebral cortex: 14.7;hippocampal formation: 12.3;olfactory bulb: 15.9" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.76e-2)" "unprognostic (2.60e-3)" "unprognostic (2.21e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.12e-1)" "unprognostic (8.96e-2)" "unprognostic (2.07e-1)" "unprognostic (3.15e-3)" "unprognostic (1.28e-3)" "unprognostic (1.05e-1)" "unprognostic (5.41e-2)" 0.1 0.2 10.5 0.0 18.9 0.0 0.0 0.0 28.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.6 33.3 21.9 3.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.4 0.8 0.0 0.3 0.1 0.0 1.7 0.0 0.1 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 18.9 0.0 28.9 21.9 3.5 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 11.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 3.7 0.0 6.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KCNJ6 "BIR1, GIRK2, hiGIRK2, KATP2, KCNJ7, Kir3.2" ENSG00000157542 "Potassium inwardly rectifying channel subfamily J member 6" P48051 21 37607373-38121345 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Congenital generalized lipodystrophy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 24.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 152.6;Horizontal cells: 245.6;Inhibitory neurons: 146.2" "Not detected" "Not detected" "Group enriched" "Detected in all" 6 "cerebral cortex: 10.3;hippocampal formation: 10.6;midbrain: 24.2" "Immune cell enhanced" "Detected in some" "basophil: 2.2;eosinophil: 1.3" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enriched" "Detected in some" 7 "LHCN-M2: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.43e-1)" "unprognostic (1.96e-1)" "unprognostic (7.71e-2)" "unprognostic (1.26e-3)" "unprognostic (6.75e-2)" "unprognostic (3.59e-1)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" "unprognostic (8.76e-2)" "unprognostic (1.64e-2)" "unprognostic (3.49e-1)" "unprognostic (1.96e-10)" "unprognostic (2.42e-1)" "unprognostic (1.46e-1)" "unprognostic (9.87e-2)" "unprognostic (1.21e-1)" 0.0 0.1 2.3 0.1 2.7 0.1 0.0 1.6 10.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.6 1.9 0.0 0.0 0.1 0.2 1.9 24.2 0.0 0.4 0.0 1.7 0.4 2.2 0.2 0.0 1.0 0.0 0.0 0.4 0.1 0.1 0.0 1.2 0.2 0.4 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.3 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.9 1.6 0.0 0.0 0.0 3.5 0.1 29.2 0.1 0.0 0.0 0.3 0.0 2.8 0.0 0.1 1.0 4.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.3 0.1 0.1 0.2 4.3 1.2 0.0 0.0 0.0 0.0 2.2 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.0 0.0 2.3 2.7 1.6 10.3 10.6 1.9 1.9 24.2 2.2 1.2 1.8 1.5 0.2 0.0 1.1 2.3 0.0 0.1 0.4 0.1 0.0 25.4 0.2 0.3 34.3 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.4 0.1 0.2 1.6 41.4 0.0 152.6 0.0 0.4 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 245.6 146.2 1.8 2.0 0.0 0.0 0.0 0.6 0.0 3.6 16.9 0.0 1.2 0.0 38.2 1.5 0.6 0.0 0.0 0.0 0.3 0.2 0.0 0.1 2.6 0.0 0.2 1.1 0.0 1.7 0.0 0.1 0.3 0.1 0.0 0.4 0.4 KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.3" "Group enriched" "Detected in many" 4 "Sertoli cells: 197.2;Smooth muscle cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "BJ: 11.1;CACO-2: 58.4;SH-SY5Y: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031066 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" 28.6 17.3 4.9 3.2 5.4 0.0 22.1 4.8 5.7 17.0 11.6 15.6 1.2 18.8 0.7 3.6 14.8 1.8 71.3 4.7 5.0 13.9 41.9 13.8 2.5 5.2 5.3 16.8 42.4 1.8 7.8 3.0 5.1 13.0 0.3 0.8 6.4 8.4 17.1 5.8 5.9 5.5 5.2 8.0 12.7 1.0 7.2 0.6 16.1 4.5 0.4 15.1 11.5 4.7 0.0 0.1 0.9 0.0 1.4 3.2 0.0 11.1 4.4 6.5 1.9 58.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.1 0.0 4.3 2.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.2 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 2.7 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.4 4.8 5.7 4.7 5.0 5.2 5.3 5.1 5.2 7.2 4.7 18.7 3.2 29.5 2.9 0.0 1.3 0.4 0.0 0.6 0.0 9.2 3.0 28.3 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 10.8 12.8 1.2 0.0 3.6 1.3 0.0 9.8 0.0 0.9 0.0 1.0 2.9 23.0 0.3 0.0 0.2 0.0 0.0 0.8 1.5 0.1 0.3 0.3 1.8 0.0 0.0 13.2 0.0 0.5 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.0 197.2 3.3 61.6 0.0 1.0 0.1 0.9 0.3 0.3 0.5 0.2 0.6 KCNJ9 "GIRK3, Kir3.3" ENSG00000162728 "Potassium inwardly rectifying channel subfamily J member 9" Q92806 1 160081538-160090563 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 65.8;choroid plexus: 20.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.9;Excitatory neurons: 23.5;Horizontal cells: 8.4;Inhibitory neurons: 12.6;Oligodendrocytes: 8.3" "Cancer enriched" "Detected in single" 35 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070478 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA070478: AB_2686270" "unprognostic (2.35e-1)" "unprognostic (6.53e-2)" "unprognostic (2.17e-2)" "unprognostic (4.73e-1)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (1.66e-1)" "unprognostic (3.33e-2)" "unprognostic (2.64e-1)" "unprognostic (3.29e-1)" "unprognostic (3.44e-1)" "unprognostic (1.49e-1)" "unprognostic (1.84e-2)" "unprognostic (2.66e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (5.24e-2)" 0.0 0.3 55.2 0.0 57.0 0.0 0.0 64.9 65.8 0.0 20.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.8 38.6 0.2 0.0 0.0 0.0 38.1 49.8 0.0 0.0 0.0 2.0 0.0 41.5 0.0 0.0 7.4 0.0 0.0 0.0 0.1 0.0 0.0 37.2 0.0 0.1 0.4 58.5 0.0 0.0 0.0 0.0 0.0 0.0 61.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.2 57.0 64.9 65.8 56.8 38.6 38.1 49.8 41.5 37.2 58.5 61.5 0.0 0.0 0.0 3.9 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.9 0.0 0.0 1.8 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.0 0.0 8.4 12.6 0.0 0.0 0.3 0.0 0.8 0.0 0.1 0.0 1.0 0.0 0.7 0.0 1.5 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.1 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 KCNK2 "K2p2.1, TREK-1" ENSG00000082482 "Potassium two pore domain channel subfamily K member 2" O95069 1 215005775-215237090 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "adrenal gland: 53.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 19.7;Inhibitory neurons: 53.9;Microglial cells: 30.0;Oligodendrocyte precursor cells: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 79.7;fHDF/TERT166: 76.3;hTERT-RPE1: 49.2;T-47d: 108.5;U-2197: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.43e-2)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (3.81e-4)" "unprognostic (2.58e-1)" "unprognostic (3.58e-2)" "unprognostic (3.48e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.98e-6)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "unprognostic (7.69e-3)" "unprognostic (7.46e-3)" 1.6 53.0 4.3 0.8 8.5 0.0 6.5 0.0 5.6 2.0 0.0 0.8 0.3 0.4 0.7 0.9 1.2 1.4 0.2 5.0 7.5 1.9 0.0 0.3 0.0 0.7 2.5 3.3 0.5 0.0 0.5 0.0 0.1 0.8 1.3 0.2 0.8 3.5 0.9 3.4 2.2 1.2 2.2 0.0 4.2 0.5 6.1 0.7 9.6 1.3 0.0 2.7 1.2 2.0 0.0 0.0 2.2 0.1 20.3 79.7 0.1 29.8 19.7 9.3 21.6 0.0 1.1 0.0 0.0 76.3 0.1 0.0 13.2 0.1 15.8 0.0 0.1 0.0 0.8 0.0 1.0 0.0 0.0 21.0 0.2 22.7 2.2 49.2 0.0 0.0 0.0 0.1 10.8 0.0 0.4 0.0 2.3 4.1 0.6 0.1 0.0 0.0 0.1 0.0 7.0 0.1 5.1 0.5 0.4 0.2 108.5 0.0 0.0 15.6 0.6 39.2 1.3 1.6 4.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 8.5 0.0 5.6 5.0 7.5 0.7 2.5 0.1 2.2 6.1 2.0 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.3 0.0 0.0 19.7 0.0 0.0 2.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.8 0.1 0.0 0.0 3.6 30.0 0.0 0.0 0.0 45.8 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.3 0.1 0.3 0.0 1.4 0.0 0.1 0.0 0.0 0.0 KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 59.2;intestine: 75.1;smooth muscle: 53.1" "Cell type enriched" "Detected in many" 6 "Peritubular cells: 354.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cell line enhanced" "Detected in some" "REH: 8.8;SK-BR-3: 2.1;U-937: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.06e-2)" "unprognostic (2.70e-4)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (8.88e-2)" "unprognostic (1.61e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (5.37e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (4.31e-2)" "unprognostic (1.04e-2)" 5.7 1.8 2.7 10.5 2.3 1.7 6.9 2.5 2.7 16.8 1.4 75.1 4.3 59.2 6.2 16.6 20.6 7.3 4.2 2.1 2.4 1.4 0.7 4.0 1.7 5.9 4.0 4.0 0.7 0.3 0.5 1.1 6.2 24.5 8.9 1.1 6.8 50.6 1.0 2.9 14.3 53.1 3.4 2.3 21.5 2.7 4.2 1.0 1.4 1.1 1.3 32.6 11.2 3.9 0.1 0.1 1.5 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.3 0.1 1.0 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.1 1.2 0.6 0.2 0.0 0.4 0.2 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.7 0.1 0.7 0.0 0.8 0.3 0.0 0.1 8.8 0.0 0.2 0.0 0.2 0.4 0.2 0.1 2.1 0.0 0.7 0.1 1.0 0.5 0.2 0.3 0.3 0.0 0.4 0.2 0.1 0.1 3.8 0.1 1.3 3.3 0.3 0.1 5.9 0.1 0.2 0.2 0.1 5.7 0.3 0.1 0.1 0.9 0.4 5.1 2.0 0.2 1.0 2.7 2.3 2.5 2.7 2.1 2.4 5.9 4.0 6.2 3.4 4.2 3.9 1.3 0.0 6.3 0.3 1.2 2.0 1.2 0.4 0.0 1.6 2.5 55.1 3.7 4.3 4.5 1.8 6.2 0.5 1.7 0.1 0.0 0.1 0.6 0.6 14.4 3.6 0.0 1.3 0.1 0.4 0.6 9.8 0.0 0.6 19.7 0.4 1.8 0.4 7.4 1.7 0.3 0.2 0.0 18.9 10.9 4.5 38.5 15.6 3.6 4.7 27.8 0.6 2.1 0.0 0.1 0.0 0.0 354.3 0.3 1.3 0.0 0.1 4.5 2.3 46.0 2.2 43.6 0.7 1.2 0.1 1.7 0.5 1.7 1.4 0.0 0.7 KCNMB2 ENSG00000197584 "Potassium calcium-activated channel subfamily M regulatory beta subunit 2" Q9Y691 3 178272932-178844429 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.4;fallopian tube: 13.9;ovary: 12.7" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 791.1;Oligodendrocyte precursor cells: 1982.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.4;SCLC-21H: 3.3" CAB022649 Uncertain NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022649: " "unprognostic (9.52e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (1.04e-2)" "unprognostic (2.43e-2)" "unprognostic (6.97e-2)" "unprognostic (6.74e-2)" "unprognostic (2.15e-1)" "unprognostic (3.58e-3)" "unprognostic (3.57e-2)" "unprognostic (1.71e-2)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-4)" "unprognostic (7.85e-2)" 0.3 5.1 2.5 0.0 3.0 0.0 0.7 1.5 4.0 1.4 0.9 1.2 0.5 2.9 35.4 0.4 13.9 0.5 5.8 4.0 2.3 3.4 0.2 1.1 0.0 3.0 2.7 12.7 4.0 0.2 1.7 0.1 2.3 0.5 0.3 0.2 0.2 1.1 0.2 0.3 0.5 1.9 2.2 1.3 3.0 0.2 2.1 0.0 0.3 0.2 0.0 0.2 0.7 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.0 0.0 0.6 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.5 3.3 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.0 1.5 4.0 4.0 2.3 3.0 2.7 2.3 2.2 2.1 2.1 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 3.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.1 8.7 0.2 0.0 13.8 0.0 311.8 0.0 0.0 2.7 0.0 1.9 0.0 12.7 1.8 0.0 0.0 0.0 791.1 0.0 4.1 0.0 0.0 0.1 2.8 0.1 0.0 12.2 0.0 0.0 0.0 1982.5 6.8 0.1 0.0 0.0 0.0 0.0 0.0 1.3 10.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 1.7 0.0 0.1 KCNMB3 "KCNMB2, KCNMBL" ENSG00000171121 "Potassium calcium-activated channel subfamily M regulatory beta subunit 3" Q9NPA1 3 179236691-179267002 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 11.2;Late spermatids: 13.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 4.8;HEL: 8.1;NB-4: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015665, HPA019185" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Mitochondria "HPA015665: AB_1852142, HPA019185: AB_1852144" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (6.76e-5)" "unprognostic (2.65e-2)" "unprognostic (2.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.59e-3)" "unprognostic (1.14e-1)" "unprognostic (9.15e-3)" "unprognostic (5.09e-2)" "unprognostic (1.87e-2)" "unprognostic (1.95e-5)" "unprognostic (5.93e-10)" "unprognostic (7.22e-2)" "unprognostic (4.72e-1)" "unprognostic (8.69e-2)" "unprognostic (3.49e-2)" 4.9 3.6 1.5 2.2 1.8 1.1 4.6 1.7 1.9 3.5 1.6 4.0 1.5 3.2 1.5 2.0 2.9 1.7 3.5 1.5 1.7 4.8 5.5 3.0 2.2 1.9 1.7 3.2 5.3 1.2 3.3 4.2 1.8 4.2 1.5 2.3 3.1 1.1 1.3 2.4 3.5 1.4 1.3 7.5 3.7 3.9 1.7 0.9 3.2 0.5 1.9 3.7 2.7 1.7 2.2 0.5 0.8 0.0 0.9 0.8 1.3 0.6 0.3 0.9 0.4 4.8 1.9 0.1 2.1 0.4 1.8 0.8 0.0 0.1 1.0 2.7 0.3 8.1 2.6 1.8 0.8 0.1 2.5 1.3 0.4 0.6 0.0 0.7 0.8 0.0 0.3 0.0 1.1 1.5 0.1 5.7 0.0 0.9 1.6 2.4 0.0 0.1 0.7 1.5 1.1 0.2 0.7 0.8 0.5 0.7 2.1 4.4 0.5 0.4 0.7 0.2 0.6 0.7 0.3 2.6 0.4 3.1 0.6 0.8 0.1 0.1 0.3 0.1 0.2 1.2 0.2 0.3 0.0 0.6 0.2 0.2 0.6 1.1 0.0 0.1 0.4 0.0 1.5 1.8 1.7 1.9 1.5 1.7 1.9 1.7 1.8 1.3 1.7 1.7 4.2 0.0 3.6 3.9 2.9 0.3 1.4 0.3 0.0 2.5 2.1 1.3 1.1 2.8 1.5 0.0 14.6 1.2 0.6 3.8 0.0 5.0 11.2 1.5 2.3 5.3 4.9 0.8 3.4 3.6 1.3 1.5 0.5 2.0 2.5 3.4 2.9 1.4 1.1 0.0 4.6 1.4 0.0 2.1 1.9 13.3 2.8 1.4 0.0 5.6 1.4 1.8 1.0 4.0 6.4 3.3 0.8 3.0 0.9 1.7 1.9 0.3 1.1 7.8 6.6 1.6 1.6 2.0 2.6 0.3 0.1 1.2 1.0 2.3 1.4 1.0 KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 91.9" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Excitatory neurons: 61.7;Horizontal cells: 13.5;Inhibitory neurons: 37.5;Oligodendrocyte precursor cells: 50.8;Spermatogonia: 28.3" "Cancer enriched" "Detected in some" 9 "glioma: 8.7" "Group enriched" "Detected in many" 4 "amygdala: 55.7;basal ganglia: 37.2;cerebellum: 27.8;cerebral cortex: 91.9;hippocampal formation: 68.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.2;AN3-CA: 35.0;NTERA-2: 19.3;SCLC-21H: 67.8;SH-SY5Y: 119.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "HPA016642: AB_1855555, HPA057112: AB_2683339" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-4)" "unprognostic (8.21e-6)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (6.06e-2)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (9.96e-2)" "unprognostic (9.39e-2)" "unprognostic (1.43e-5)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" 0.0 6.2 55.7 0.1 37.2 0.0 0.0 27.8 91.9 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.3 0.2 68.1 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 1.1 0.0 19.1 0.0 0.1 1.6 0.0 2.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 10.6 1.0 0.0 0.0 0.0 0.0 0.0 0.1 12.9 0.0 0.0 21.2 35.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.6 0.0 8.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 19.3 0.5 0.2 0.0 0.0 0.1 0.0 0.0 67.8 119.3 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 55.7 37.2 27.8 91.9 68.1 0.0 2.6 0.0 0.1 0.0 1.0 12.9 0.6 0.0 0.0 7.2 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 16.5 0.0 0.1 1.0 0.0 0.0 61.7 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.5 37.5 0.2 0.0 0.0 0.0 8.1 0.6 0.1 0.0 1.0 0.0 0.9 0.0 50.8 2.1 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.0 0.1 0.1 7.4 28.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 KCTD7 "CLN14, EPM3, FLJ32069" ENSG00000243335 "Potassium channel tetramerization domain containing 7" Q96MP8 7 66628881-66649067 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 65.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Oligodendrocytes: 42.7;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.53e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (8.07e-4)" "unprognostic (1.30e-3)" "unprognostic (3.74e-2)" "unprognostic (1.34e-2)" "unprognostic (4.49e-5)" "unprognostic (1.26e-2)" "unprognostic (2.64e-1)" "unprognostic (2.97e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.45e-1)" "unprognostic (7.76e-2)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.58e-2)" "unprognostic (3.19e-2)" 9.4 11.6 18.3 8.7 21.8 5.6 7.8 22.2 20.4 16.0 12.7 17.0 5.1 14.0 13.7 4.8 13.0 7.1 10.1 17.8 19.3 8.7 5.9 7.9 12.4 24.7 21.6 20.8 5.2 10.0 13.8 7.8 24.6 10.9 6.9 65.7 6.6 10.1 5.9 6.3 12.6 8.6 19.7 10.9 10.8 17.5 23.1 8.0 10.0 6.6 12.1 16.6 10.4 32.1 4.5 6.3 17.5 12.8 8.2 10.5 1.2 6.6 7.0 10.2 9.6 9.0 5.3 14.4 1.7 8.3 25.0 2.4 14.4 2.3 10.4 13.0 6.4 1.6 16.0 7.8 4.4 3.9 11.6 6.6 7.3 8.4 5.0 14.4 5.3 6.9 13.8 12.5 8.5 1.6 3.8 5.7 11.1 1.6 6.8 4.7 7.2 5.8 6.9 1.6 8.8 16.2 5.5 3.5 15.4 16.8 5.6 4.5 6.8 13.1 9.5 4.5 5.8 5.4 4.0 11.2 17.2 5.2 10.2 2.5 1.2 6.9 3.3 0.9 3.6 2.1 2.8 2.7 1.2 3.4 1.8 2.7 0.9 2.6 1.3 1.1 3.1 1.4 18.3 21.8 22.2 20.4 17.8 19.3 24.7 21.6 24.6 19.7 23.1 32.1 5.4 3.2 9.0 20.2 10.5 1.1 1.7 2.8 8.0 17.1 3.8 3.0 12.0 0.0 2.9 0.0 37.5 5.2 9.3 1.8 1.9 1.2 9.0 4.6 10.2 4.8 8.4 3.4 14.9 1.2 2.2 6.3 4.1 3.3 5.1 12.5 6.8 2.0 5.9 18.5 16.5 2.7 0.0 3.8 1.6 18.2 6.5 6.6 1.8 27.2 4.2 20.3 12.3 7.5 42.7 1.2 5.2 12.4 7.1 1.5 4.0 1.7 3.0 53.1 6.6 5.8 7.2 13.0 9.9 1.7 1.1 2.7 10.7 5.4 2.2 0.6 KIAA1549 ENSG00000122778 KIAA1549 Q9HCM3 7 138831381-138981389 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 92.2;Inhibitory neurons: 54.6;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "PC-3: 20.6;SH-SY5Y: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019560 Uncertain Approved "Nuclear membrane,Intermediate filaments" NA NA 14000 "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" "Intermediate filaments" "HPA019560: AB_1852418" "unprognostic (7.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.63e-1)" "unprognostic (6.85e-2)" "unprognostic (2.29e-1)" "unprognostic (8.86e-2)" "unprognostic (2.55e-2)" "unprognostic (6.40e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (2.33e-2)" "unprognostic (8.30e-2)" "prognostic favorable (3.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "unprognostic (2.38e-1)" "unprognostic (1.28e-2)" 0.6 1.7 2.7 0.3 3.0 0.3 1.5 0.0 4.4 1.4 0.0 0.8 0.7 1.7 1.8 0.5 2.2 1.0 1.2 4.3 0.8 3.9 0.4 1.8 0.2 1.6 2.5 1.2 6.3 2.4 1.8 1.3 0.0 1.5 0.7 5.7 2.4 5.5 0.5 0.8 0.7 1.3 1.4 0.3 1.3 1.2 2.5 2.4 0.7 0.8 0.2 1.1 0.6 2.4 4.9 9.2 9.1 14.9 0.1 0.0 4.2 5.2 4.6 2.6 3.4 8.4 2.6 0.0 2.9 8.2 8.6 1.0 5.7 1.4 3.6 2.5 3.8 2.6 11.5 2.2 1.3 3.8 3.2 1.2 2.8 0.9 1.4 3.5 4.8 3.4 1.7 0.1 3.6 4.5 2.9 4.7 7.8 4.1 20.6 6.8 4.5 0.0 1.7 3.3 11.8 21.5 2.6 5.2 2.2 5.1 3.7 2.4 3.3 2.9 2.8 0.1 5.1 0.9 0.0 0.1 4.0 1.4 7.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.0 0.0 4.4 4.3 0.8 1.6 2.5 0.0 1.4 2.5 2.4 2.0 0.0 2.2 11.8 0.1 0.5 2.1 1.6 0.6 18.5 6.3 4.6 2.5 0.0 2.9 7.3 56.3 2.5 0.2 0.3 0.0 2.3 0.5 8.5 8.1 4.8 10.8 1.3 92.2 3.2 2.2 3.0 3.6 8.0 16.5 13.8 2.2 0.8 0.5 3.3 54.6 2.5 6.1 0.8 1.2 0.2 1.5 0.5 1.8 26.2 0.0 7.2 0.0 69.9 2.2 5.0 1.4 2.6 1.0 3.1 0.5 8.1 12.2 29.2 6.6 2.2 2.9 0.3 7.2 0.1 0.9 1.5 1.1 2.4 2.9 1.6 KIR2DL4 "103AS, 15.212, CD158D" ENSG00000189013 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4" Q99706 19 54803535-54814517 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 4.5" "Group enriched" "Detected in some" 6 "dendritic cells: 23.6;NK-cells: 6.2;T-cells: 20.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "NK-cell: 2.8" "Lineage enriched" "Detected in single" 28 "NK-cells: 2.8" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.84e-2)" "unprognostic (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (5.95e-4)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.92e-5)" "unprognostic (5.15e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.53e-8)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (6.10e-4)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.2 2.5 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.1 0.0 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 19.6;liver: 17.7;pancreas: 6.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.6;Enteroendocrine cells: 17.4;Hepatocytes: 51.4;Intestinal goblet cells: 12.1;Spermatocytes: 39.5" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "ASC diff: 6.7;Hep G2: 25.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" 19.6 0.1 0.2 0.2 0.4 0.3 3.5 0.9 0.6 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.2 0.2 17.7 1.6 0.0 0.3 0.0 0.0 6.0 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.3 2.8 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.0 6.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 25.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.2 0.4 0.9 0.6 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.6 3.2 19.6 0.0 0.7 0.5 1.1 1.4 0.0 1.6 0.7 1.1 1.2 0.0 1.2 0.0 0.0 0.4 0.5 1.6 0.0 1.1 8.5 4.4 1.5 0.4 17.4 0.0 0.5 4.3 1.5 0.5 2.6 2.2 0.0 0.2 0.4 51.4 0.2 1.7 0.6 12.1 2.0 1.0 0.6 3.2 1.5 0.4 1.8 0.0 0.1 0.4 0.0 0.5 0.2 0.9 4.8 0.7 0.0 1.2 2.1 1.1 0.4 2.3 0.0 1.2 0.5 39.5 0.9 2.0 0.9 1.4 0.8 0.5 1.1 1.1 KNCN "FLJ32011, KINO, L5" ENSG00000162456 Kinocilin A6PVL3 1 46545641-46551647 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 11 "brain: 3.3" "Group enriched" "Detected in some" 46 "Early spermatids: 15.1;Late spermatids: 31.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hypothalamus: 3.3;medulla oblongata: 1.8;midbrain: 2.3;pons: 2.0;thalamus: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.99e-3)" "unprognostic (2.28e-2)" "unprognostic (2.80e-2)" 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.3 0.0 0.0 0.0 0.0 1.8 2.3 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.2 0.5 3.3 1.8 2.3 2.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTCAP2 KCP2 ENSG00000163463 "Keratinocyte associated protein 2" Q8N6L1 1 155169408-155173475 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.57e-2)" "unprognostic (5.93e-2)" "unprognostic (2.63e-2)" "unprognostic (2.67e-1)" "unprognostic (1.53e-1)" "unprognostic (4.76e-2)" "unprognostic (2.44e-3)" "unprognostic (3.64e-1)" "unprognostic (3.38e-1)" "unprognostic (2.13e-2)" "unprognostic (7.81e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (9.70e-11)" "unprognostic (3.17e-1)" "unprognostic (8.95e-2)" "unprognostic (6.30e-2)" "unprognostic (4.94e-3)" 183.2 179.0 153.7 82.9 160.0 113.0 186.4 165.1 197.1 206.8 161.1 178.7 105.1 203.1 309.3 136.3 165.8 104.6 185.5 152.6 163.7 157.0 226.1 143.3 104.0 167.1 159.7 177.0 451.1 155.2 182.6 93.3 169.7 139.8 121.2 50.4 207.5 155.2 171.1 130.2 147.0 139.1 160.0 156.0 209.9 203.8 159.3 99.6 180.3 112.4 126.1 160.7 158.4 171.0 171.1 302.5 141.8 157.5 406.7 291.1 152.1 197.0 225.2 226.2 188.5 369.9 321.6 129.2 303.3 357.0 130.3 230.5 160.2 221.2 142.5 180.6 327.0 143.5 333.2 207.5 377.1 276.8 154.3 277.6 498.5 264.6 340.2 175.3 202.0 246.4 207.8 581.7 234.0 572.8 152.0 273.6 152.4 564.9 399.1 176.1 90.2 692.0 335.5 254.6 232.8 147.7 193.5 340.8 222.6 208.4 248.9 445.8 138.6 145.6 138.6 124.1 193.4 332.5 302.4 222.4 239.1 266.5 163.0 657.8 346.6 372.1 445.7 304.5 504.5 497.9 498.4 474.3 371.6 441.5 374.6 405.8 152.9 330.1 260.7 840.7 513.4 491.8 153.7 160.0 165.1 197.1 152.6 163.7 167.1 159.7 169.7 160.0 159.3 171.0 170.9 70.5 119.1 10.1 161.8 63.2 53.4 187.5 152.0 13.9 158.3 151.1 1.3 148.7 132.1 207.8 4.2 79.2 146.7 150.7 45.0 219.3 257.4 113.6 153.2 143.6 131.7 119.2 5.1 298.2 211.4 153.4 189.1 159.7 84.9 52.4 201.7 235.3 160.9 8.4 6.2 246.7 105.8 156.3 173.9 95.0 228.3 122.9 252.5 12.2 110.7 41.5 138.0 6.0 12.6 244.5 206.1 164.4 517.4 49.9 267.4 179.0 146.8 15.2 118.3 76.2 156.1 349.7 78.0 194.1 90.5 94.1 162.9 43.1 183.3 59.3 LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.3;Inhibitory neurons: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: AB_2680678" "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavorable (9.67e-4)" "prognostic unfavorable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" 4.2 4.9 6.1 5.0 6.7 9.9 5.3 10.8 9.3 6.7 3.4 7.8 12.3 7.2 9.8 5.1 6.1 6.2 11.3 5.3 7.8 9.5 8.6 5.1 5.4 2.9 3.3 4.9 5.9 6.3 3.2 4.3 3.1 7.8 7.9 10.6 4.6 7.0 9.6 6.6 9.5 8.7 0.8 5.3 5.3 8.3 7.0 6.4 10.9 4.1 5.4 4.9 3.7 10.2 16.9 21.6 11.3 19.3 2.6 5.7 16.3 11.8 11.7 12.3 10.3 21.8 19.0 10.5 10.7 18.4 15.2 18.3 38.8 16.0 12.1 13.6 13.0 19.4 12.8 21.6 12.0 28.1 14.3 4.6 12.4 13.0 18.0 8.0 8.7 6.0 18.3 9.5 9.6 12.8 16.1 16.5 12.5 13.6 12.4 15.6 22.9 21.8 9.7 24.7 13.1 20.5 26.4 17.4 15.7 7.7 12.6 9.5 10.0 22.1 18.2 12.4 18.9 7.0 16.2 23.2 22.7 20.1 17.3 15.9 2.3 5.0 5.2 3.8 6.2 7.5 8.3 6.7 2.8 9.7 11.7 11.5 7.2 4.6 3.6 2.0 4.2 3.0 6.1 6.7 10.8 9.3 5.3 7.8 2.9 3.3 3.1 0.8 7.0 10.2 6.5 9.6 6.9 27.1 11.4 7.1 5.0 8.4 6.8 15.5 6.9 5.3 20.1 18.6 8.7 14.7 27.1 5.2 6.7 10.4 0.0 7.7 3.9 12.0 7.0 7.7 13.1 10.3 67.3 16.4 5.3 6.7 3.1 9.4 3.8 11.6 8.6 21.5 6.1 15.2 86.8 14.3 0.0 5.7 3.9 1.4 5.6 3.4 5.4 45.0 2.4 7.9 5.2 50.8 37.3 12.9 8.6 9.1 5.2 5.4 21.4 12.1 16.6 18.2 6.6 10.9 16.3 13.9 21.0 7.9 6.7 1.9 9.1 10.9 17.0 4.7 LEMD2 "dJ482C21.1, LEM2, NET25" ENSG00000161904 "LEM domain nuclear envelope protein 2" Q8NC56 6 33771202-33789130 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017340 Supported Supported "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "HPA017340: AB_2296925" "unprognostic (9.01e-2)" "unprognostic (7.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.12e-2)" "unprognostic (2.98e-1)" "unprognostic (8.29e-3)" "unprognostic (6.53e-2)" "unprognostic (5.98e-2)" "unprognostic (4.42e-2)" "unprognostic (7.03e-2)" "unprognostic (1.67e-3)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (2.43e-1)" "unprognostic (7.54e-2)" "unprognostic (3.82e-2)" "unprognostic (7.12e-2)" 40.5 45.8 46.0 35.0 47.9 63.3 39.6 53.1 50.8 52.6 44.6 45.3 31.9 44.1 29.7 50.2 45.9 30.0 46.7 43.9 44.0 51.5 49.9 51.2 45.4 52.0 47.0 53.7 54.5 39.3 56.5 38.5 47.9 51.9 30.0 29.7 43.3 31.3 37.4 51.8 50.1 30.4 46.3 70.1 44.9 45.5 47.2 46.1 53.0 28.1 41.6 43.8 44.9 54.4 36.6 40.5 67.3 66.1 37.6 40.3 50.9 39.1 59.7 48.5 50.9 30.6 37.8 33.8 53.5 55.6 136.7 62.0 39.4 52.1 34.0 35.9 36.6 12.7 45.8 40.3 78.4 26.1 42.6 44.3 96.5 51.6 88.1 80.0 52.8 43.9 36.3 38.3 42.8 30.8 48.6 64.1 39.2 53.5 23.2 31.8 27.8 28.3 52.0 50.5 47.8 37.8 23.4 74.0 52.6 68.0 49.5 70.7 24.6 67.8 26.3 36.6 46.5 49.8 43.0 24.0 26.7 40.3 83.0 1.6 1.7 3.2 2.3 1.5 2.9 2.2 2.5 2.3 1.7 2.3 2.0 2.3 1.4 1.5 2.1 2.9 2.8 1.2 46.0 47.9 53.1 50.8 43.9 44.0 52.0 47.0 47.9 46.3 47.2 54.4 19.8 3.2 9.0 16.0 17.4 10.8 13.4 7.9 14.2 18.6 10.0 7.1 10.0 8.6 5.2 9.2 18.8 24.9 18.6 24.3 1.9 9.4 24.9 7.5 10.1 18.5 5.4 8.6 14.5 6.8 36.6 12.2 15.3 10.6 12.7 16.6 12.5 7.7 17.5 43.7 17.4 17.7 6.1 14.5 12.4 44.2 10.5 13.5 12.4 14.0 9.4 14.0 13.4 14.6 18.2 13.2 20.1 16.1 11.9 14.6 14.8 6.6 7.2 13.1 19.7 12.7 15.2 24.6 7.4 8.9 10.2 29.8 15.2 12.5 15.9 13.2 LEMD3 MAN1 ENSG00000174106 "LEM domain containing 3" Q9Y2U8 12 65169583-65248355 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025078, HPA076986" Uncertain Supported "Nuclear membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear membrane" "HPA025078: AB_10601908, HPA076986: AB_2686821" "unprognostic (2.10e-2)" "unprognostic (6.83e-3)" "unprognostic (1.63e-3)" "unprognostic (1.76e-3)" "unprognostic (2.79e-1)" "unprognostic (1.04e-1)" "unprognostic (1.68e-3)" "unprognostic (7.22e-2)" "unprognostic (3.06e-2)" "unprognostic (4.16e-2)" "unprognostic (8.89e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.30e-4)" "unprognostic (4.37e-2)" "unprognostic (3.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.72e-1)" 9.3 7.3 6.6 10.5 8.0 20.8 10.6 12.2 9.4 8.6 6.9 10.4 9.6 12.2 8.8 8.1 9.3 6.9 7.2 8.5 6.3 9.6 9.5 9.3 13.5 6.0 6.9 11.9 9.8 14.7 5.3 7.2 6.4 9.4 10.0 16.6 9.3 7.7 8.7 8.0 9.4 8.3 6.9 11.4 9.7 15.6 6.9 13.6 10.6 9.6 12.3 8.9 8.1 7.7 19.7 10.9 17.1 17.2 11.8 13.6 11.7 22.4 12.0 11.0 9.5 13.7 12.4 53.2 14.1 13.9 8.5 25.8 18.5 16.0 15.9 12.8 21.4 21.7 10.2 10.5 9.0 33.4 15.1 9.9 16.9 13.1 17.6 15.5 13.1 14.6 28.9 24.6 15.6 11.5 17.5 17.3 23.5 8.9 11.1 40.6 16.8 26.8 13.8 21.4 17.8 10.9 22.5 22.7 14.0 16.4 22.6 26.0 18.1 13.4 14.3 12.7 15.7 17.5 17.7 32.3 11.2 16.1 16.8 1.0 0.7 1.4 1.5 0.6 2.0 1.8 2.0 2.0 1.0 1.9 1.9 2.1 0.8 1.6 0.9 2.1 1.9 0.7 6.6 8.0 12.2 9.4 8.5 6.3 6.0 6.9 6.4 6.9 6.9 7.7 21.7 38.5 21.0 29.7 29.0 32.1 19.4 10.4 14.8 20.1 15.3 11.3 14.7 8.6 13.5 11.0 18.8 8.0 32.7 20.2 0.0 10.3 2.1 16.3 18.0 17.4 14.9 16.8 50.0 13.1 4.6 18.5 13.3 19.8 22.2 12.5 14.6 13.3 6.5 16.8 58.2 13.7 12.2 13.7 16.4 3.2 15.8 16.4 17.8 49.6 16.1 20.3 17.5 53.3 52.7 14.6 14.5 12.4 23.6 18.9 7.8 4.3 19.3 21.5 6.6 23.5 19.2 43.3 35.3 17.6 39.1 14.4 21.9 13.7 11.8 22.9 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 80.5;Fibroblasts: 94.2;Hepatocytes: 175.2;Langerhans cells: 66.6;Microglial cells: 129.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "K-562: 114.7;RPTEC TERT1: 52.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 24.3 7.2 5.2 3.9 5.1 5.0 20.6 4.9 6.5 21.5 25.0 5.9 3.9 24.6 6.7 9.2 16.1 14.7 6.9 5.3 12.3 7.8 130.4 22.5 9.5 5.2 5.7 25.0 3.0 2.9 11.7 5.3 5.2 9.0 5.1 2.5 11.9 7.3 2.1 15.1 5.6 18.7 6.3 3.2 13.7 3.9 7.7 4.7 10.4 32.1 5.7 9.1 4.8 5.2 3.3 2.0 2.6 2.9 11.5 10.6 9.0 14.2 8.1 4.8 4.5 1.5 7.6 1.4 10.1 18.0 1.3 2.7 2.2 12.3 12.7 17.2 3.7 18.8 7.9 0.3 7.0 1.4 1.6 29.7 6.8 2.9 10.8 36.2 13.9 1.4 114.7 2.2 22.5 0.9 1.4 0.4 4.2 2.0 0.2 0.4 2.2 0.8 52.3 1.4 1.6 26.3 3.5 1.5 4.0 14.9 5.0 5.0 5.3 4.9 10.0 1.1 7.8 3.0 2.2 0.5 10.2 5.3 4.8 4.5 0.8 1.2 0.5 0.6 0.4 0.2 0.4 0.4 0.7 0.1 0.3 0.5 0.4 0.4 0.7 0.5 1.0 0.7 5.2 5.1 4.9 6.5 5.3 12.3 5.2 5.7 5.2 6.3 7.7 5.2 97.7 0.0 11.3 47.0 2.6 35.3 1.9 3.3 2.2 4.0 3.1 3.3 6.6 11.5 4.2 9.2 0.0 1.6 1.6 0.5 3.9 1.5 1.1 2.0 4.4 80.5 0.0 10.3 20.9 1.1 2.6 94.2 2.6 12.8 1.3 2.6 52.5 175.2 2.0 1.7 21.8 0.8 2.0 6.3 66.6 2.3 34.5 6.1 35.6 129.3 3.4 0.4 2.1 29.1 24.5 1.7 1.9 7.5 2.4 7.5 0.7 6.4 2.6 1.0 0.0 41.1 10.3 1.1 1.2 4.1 29.5 2.6 4.7 3.3 0.8 2.1 LEPROTL1 "my047, Vps55" ENSG00000104660 "Leptin receptor overlapping transcript like 1" O95214 8 30095408-30177208 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047911 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "HPA047911: AB_2680206" "unprognostic (4.42e-2)" "unprognostic (1.33e-2)" "prognostic favorable (9.04e-4)" "unprognostic (1.92e-2)" "unprognostic (3.77e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-3)" "unprognostic (5.24e-2)" "unprognostic (2.44e-1)" "unprognostic (4.73e-3)" "unprognostic (2.30e-1)" "unprognostic (9.44e-3)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (2.53e-1)" 37.0 48.5 20.0 32.6 20.7 55.7 25.0 23.8 26.0 20.3 16.7 28.4 20.4 21.4 25.6 18.8 21.1 23.5 34.0 22.7 20.3 29.4 38.8 29.7 39.4 19.1 18.9 20.4 22.7 21.8 15.3 75.9 19.6 17.8 26.0 25.7 20.7 22.1 13.3 21.8 26.5 24.0 19.5 33.1 25.3 34.1 19.8 66.3 15.3 14.9 36.1 26.4 17.6 21.8 39.3 48.9 67.8 52.0 36.2 27.4 27.0 55.6 45.1 37.9 60.7 40.4 41.2 24.3 45.6 51.7 47.9 37.6 52.3 39.2 60.8 32.9 31.3 75.0 35.0 74.6 55.9 23.1 55.3 31.5 41.4 42.7 27.0 43.7 47.0 57.4 79.4 40.1 45.3 49.6 52.4 31.4 47.1 73.9 30.8 41.8 27.1 28.9 48.7 48.3 15.4 55.3 30.4 31.2 50.5 44.8 29.0 22.5 41.2 23.0 114.6 19.1 42.8 15.6 24.0 49.3 33.8 49.4 55.0 252.3 119.8 171.3 142.3 121.9 188.3 38.2 246.6 174.7 83.3 33.4 347.3 259.9 229.9 102.3 160.6 115.4 338.9 284.5 20.0 20.7 23.8 26.0 22.7 20.3 19.1 18.9 19.6 19.5 19.8 21.8 97.7 35.3 42.3 13.7 62.2 29.2 16.5 57.5 21.1 23.2 38.6 29.3 40.9 42.9 42.4 42.3 12.5 56.2 196.6 39.1 19.6 113.4 122.2 44.8 40.3 67.2 33.0 30.1 25.2 102.3 105.2 36.4 35.7 34.3 141.4 149.2 69.3 74.9 98.3 20.2 25.6 35.4 67.1 93.1 70.3 79.7 35.4 85.1 62.2 15.9 86.3 27.6 117.4 24.1 21.5 83.9 36.7 26.4 78.0 15.2 48.7 83.1 65.7 26.3 52.6 21.8 71.3 122.6 68.4 31.1 34.7 51.9 351.9 48.2 33.2 19.3 LETMD1 "HCCR, HCCR-1, HCCR-2, HCCR1, HCCR2, SLC55A3" ENSG00000050426 "LETM1 domain containing 1" Q6P1Q0 12 51047962-51060424 "Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074361 Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Mitochondria "Nucleoplasm, Nucleoli" "HPA074361: AB_2686682" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.08e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.11e-1)" "unprognostic (2.20e-2)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "unprognostic (5.05e-2)" "unprognostic (7.86e-2)" "unprognostic (6.57e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.07e-1)" "unprognostic (7.79e-2)" "unprognostic (2.58e-1)" "prognostic favorable (3.16e-4)" 31.2 27.0 17.5 11.7 19.2 22.3 29.9 17.8 24.2 19.6 22.8 24.3 36.0 19.4 23.8 13.1 32.4 17.1 18.9 20.0 19.0 32.7 40.3 17.6 18.2 19.3 17.2 36.6 37.1 32.4 19.4 13.7 20.0 18.9 28.3 20.9 27.5 19.4 23.6 19.7 24.5 19.8 18.3 16.5 24.5 13.3 18.7 22.4 37.2 27.8 20.8 17.0 15.5 19.5 19.1 16.7 12.7 33.5 54.9 89.9 12.6 19.4 31.7 19.9 22.2 41.2 38.6 50.2 23.4 20.9 14.2 34.7 25.8 26.1 22.6 18.3 32.4 36.5 23.6 32.8 36.1 32.8 25.6 75.4 82.3 23.7 55.5 60.4 20.3 47.7 38.1 35.4 27.5 29.5 23.2 33.1 8.4 23.6 45.2 19.5 15.0 27.4 25.2 28.3 37.3 16.7 14.7 32.2 45.4 12.4 51.1 29.2 15.6 12.8 13.4 20.9 11.2 32.2 53.8 21.6 23.1 21.1 9.1 3.7 9.6 3.9 10.1 10.8 15.1 15.0 17.0 12.8 9.3 9.2 20.5 19.1 3.0 12.6 16.2 8.3 17.0 12.5 17.5 19.2 17.8 24.2 20.0 19.0 19.3 17.2 20.0 18.3 18.7 19.5 27.0 22.4 29.5 41.1 38.8 49.6 40.0 51.9 66.0 20.9 66.2 64.8 12.6 35.8 20.5 23.9 10.4 49.6 31.7 20.3 92.0 17.2 9.3 23.6 22.2 26.2 27.7 35.5 22.6 32.7 23.3 32.9 31.6 18.4 25.4 29.7 25.7 19.1 30.3 18.5 26.5 36.0 28.5 56.3 35.7 17.0 32.6 27.9 39.2 13.1 31.5 31.8 23.7 16.1 25.4 15.6 26.8 30.5 29.5 26.0 87.0 65.7 25.1 18.9 26.3 33.5 31.8 20.5 26.0 44.2 44.3 27.9 38.8 55.4 52.7 26.6 LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 32.3;dendritic cells: 37.4;Kupffer cells: 87.3;Macrophages: 73.8;Microglial cells: 30.9;monocytes: 39.6;Plasma cells: 34.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 19 "Daudi: 5.6;THP-1: 2.9" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" 2.5 1.6 0.2 7.0 0.2 1.2 1.0 0.2 0.3 0.6 0.2 2.1 0.1 0.4 0.0 0.7 1.5 0.0 0.9 0.2 0.3 1.2 2.2 7.6 5.6 0.6 0.5 0.6 0.7 0.0 0.9 0.1 0.8 1.1 0.4 0.0 1.2 0.2 0.2 0.1 6.0 2.7 0.7 36.1 1.1 0.2 0.7 0.0 0.8 0.0 0.3 2.1 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.1 0.0 1.4 39.3 0.0 2.3 0.0 1.2 5.6 2.4 0.0 0.8 0.2 0.0 63.7 2.2 0.0 5.5 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.5 0.8 0.7 0.7 1.4 0.9 0.0 2.2 0.0 32.3 0.3 0.3 0.0 0.0 0.0 0.3 0.8 1.0 1.5 2.5 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.1 0.2 0.5 0.0 2.5 0.0 2.5 0.7 15.9 0.0 0.1 0.0 0.0 87.3 2.2 0.0 0.0 73.8 0.0 30.9 39.6 0.3 9.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 2.2 LMBR1L "FLJ10494, KIAA1174" ENSG00000139636 "Limb development membrane protein 1 like" Q6UX01 12 49097136-49110900 "Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Granulosa cells: 722.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-1)" "unprognostic (6.56e-3)" "unprognostic (1.17e-1)" "unprognostic (1.77e-3)" "unprognostic (1.59e-1)" "prognostic favorable (3.50e-4)" "unprognostic (2.72e-2)" "prognostic unfavorable (4.45e-7)" "unprognostic (2.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-3)" 6.5 9.4 12.6 4.0 13.0 4.3 4.4 14.8 18.2 6.4 12.3 8.2 6.4 7.6 6.7 8.8 7.2 5.1 11.6 12.8 13.6 10.3 6.2 5.5 7.3 13.3 12.8 8.6 5.9 5.0 8.5 11.0 13.3 6.6 4.5 5.9 5.6 6.9 6.0 5.2 8.8 6.9 12.5 7.5 5.9 25.7 12.7 11.0 3.9 6.1 6.5 8.7 6.2 14.0 7.5 10.5 13.3 13.7 9.3 13.4 14.5 7.0 11.1 9.3 8.5 10.7 5.9 3.2 5.5 14.4 5.9 3.6 9.8 5.0 5.7 12.3 15.6 7.5 6.1 9.8 17.9 5.3 11.7 15.3 6.8 13.3 7.9 25.4 29.5 13.0 19.7 4.9 8.9 3.3 9.3 14.8 6.2 20.1 7.6 6.5 5.5 3.7 6.9 15.1 7.4 6.5 5.9 5.8 13.4 11.7 5.0 7.0 28.6 6.0 3.7 4.0 2.7 8.9 5.9 4.6 8.8 4.8 3.5 24.1 19.7 51.7 12.9 16.4 11.0 17.3 13.2 14.7 14.1 18.8 18.1 15.4 9.6 6.0 21.1 10.1 22.0 17.4 12.6 13.0 14.8 18.2 12.8 13.6 13.3 12.8 13.3 12.5 12.7 14.0 26.5 6.4 20.0 16.6 26.9 15.4 13.0 13.1 23.9 37.0 14.2 10.9 7.5 7.2 9.9 9.2 20.9 14.8 29.9 15.0 3.9 16.1 104.8 6.1 11.1 27.6 47.1 11.6 14.9 10.2 39.3 21.1 9.7 9.0 17.7 722.7 17.9 8.6 16.7 32.0 14.8 12.5 16.2 13.2 41.5 156.3 13.7 23.4 21.4 14.0 27.6 9.3 27.8 8.5 13.0 17.5 15.5 6.8 36.3 14.0 51.2 3.4 6.8 31.1 13.1 17.6 24.1 14.7 12.5 15.0 14.8 22.3 33.0 18.2 13.2 18.3 LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 19.3;Endometrial stromal cells: 24.6;Hofbauer cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 159.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 15000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" Nucleoplasm "HPA014205: AB_2234186" "unprognostic (4.93e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-2)" "unprognostic (8.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (4.17e-3)" "unprognostic (1.63e-1)" "unprognostic (9.27e-2)" "unprognostic (2.35e-3)" "unprognostic (3.43e-2)" 13.5 8.9 6.3 7.7 10.1 30.1 9.8 10.2 8.7 12.0 4.2 12.0 7.6 8.6 6.2 13.1 6.3 7.7 12.2 7.6 13.2 8.2 14.4 6.7 7.2 11.3 9.2 10.7 5.5 15.6 6.0 6.1 14.1 10.1 10.2 24.1 6.4 8.2 34.1 12.1 7.5 9.6 11.3 5.9 7.8 24.5 9.3 14.0 8.8 26.8 7.9 7.6 9.2 19.0 24.5 12.3 28.3 40.1 58.5 36.1 14.3 70.8 33.7 32.2 45.1 17.0 28.2 24.4 39.4 31.5 42.3 26.5 26.9 18.9 44.6 37.5 27.4 27.6 14.8 15.2 13.8 47.2 32.9 29.9 17.5 31.4 15.4 26.4 6.0 19.3 28.9 31.5 44.9 16.0 31.4 18.8 9.2 24.9 23.4 31.3 28.6 18.0 13.6 22.2 32.6 32.9 31.3 17.5 24.1 26.6 26.2 15.4 9.2 159.0 23.6 53.9 33.7 18.5 36.6 20.3 49.4 15.2 30.4 3.7 4.2 7.9 4.9 4.8 5.8 4.3 4.2 5.4 3.9 3.3 4.2 6.7 3.4 6.5 4.5 4.4 7.8 3.4 6.3 10.1 10.2 8.7 7.6 13.2 11.3 9.2 14.1 11.3 9.3 19.0 10.8 19.2 13.6 0.0 4.4 0.0 0.0 0.0 0.0 0.0 19.3 15.0 0.0 0.0 6.2 16.5 0.0 5.7 14.5 0.0 5.9 14.0 0.0 10.1 24.6 3.5 0.0 0.0 0.0 9.6 17.3 12.8 0.0 12.7 11.4 10.6 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.3 0.0 0.0 9.1 8.7 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 8.3 7.2 12.0 0.0 0.0 LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.2;Gastric mucus-secreting cells: 131.5;Urothelial cells: 129.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 108.5;OE19: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" 19.7 6.2 18.0 12.2 18.3 6.7 17.8 12.8 38.5 21.6 4.0 44.8 30.9 14.4 9.4 36.1 18.7 17.0 26.0 18.8 21.2 9.3 3.4 10.0 9.7 26.2 12.8 11.8 10.2 7.1 11.8 5.1 26.0 11.1 35.9 4.9 11.8 8.8 8.3 18.6 31.2 16.7 8.5 16.3 39.7 3.3 18.1 8.7 8.4 8.0 11.2 22.2 28.9 21.6 13.7 31.9 15.7 12.6 41.4 41.9 7.5 18.8 31.5 17.6 24.0 11.6 36.0 12.4 38.4 26.3 41.3 108.5 13.8 35.5 7.8 25.2 8.2 12.5 13.6 11.3 8.5 13.5 12.3 31.3 15.8 16.6 21.4 40.6 29.0 22.1 8.3 23.6 33.1 13.3 11.9 26.1 15.7 113.7 26.0 14.7 17.6 25.1 38.7 32.4 12.6 9.5 11.3 14.9 7.3 18.2 11.5 17.9 36.4 32.5 19.6 51.8 18.3 28.5 23.9 4.3 24.3 37.0 7.6 0.1 0.8 3.6 2.7 1.1 6.6 1.6 3.2 4.2 1.3 2.3 1.8 1.7 3.5 1.7 1.4 4.6 5.6 0.8 18.0 18.3 12.8 38.5 18.8 21.2 26.2 12.8 26.0 8.5 18.1 21.6 31.0 25.6 5.9 8.8 13.1 4.8 7.8 35.5 15.4 15.5 5.8 8.3 12.8 25.8 63.1 9.2 4.2 4.9 15.7 85.2 1.9 11.6 0.0 7.1 7.8 31.9 25.3 9.2 57.5 9.8 17.1 9.6 131.5 10.1 12.0 5.5 23.6 0.7 7.9 10.1 53.3 58.0 24.4 8.1 9.7 1.2 15.5 6.3 8.8 9.4 5.7 1.7 9.2 12.5 7.2 43.1 83.4 6.8 29.1 9.7 58.7 2.8 40.7 5.9 13.1 5.1 11.9 2.5 8.1 20.3 6.1 2.5 19.9 8.6 71.8 129.9 LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 213.7;Inhibitory neurons: 192.6;Microglial cells: 161.1;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Approved "Golgi apparatus,Cytosol" NA NA 340000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "HPA019366: AB_2138441, HPA023597: AB_1853256" "unprognostic (2.60e-1)" "unprognostic (4.70e-2)" "unprognostic (1.64e-3)" "unprognostic (4.49e-3)" "unprognostic (4.38e-1)" "unprognostic (8.65e-2)" "unprognostic (5.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.88e-2)" "prognostic favorable (2.22e-16)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (4.79e-1)" "unprognostic (3.00e-1)" 7.3 10.7 3.4 9.3 6.9 11.1 22.7 11.1 3.8 13.1 18.6 16.7 13.3 6.9 14.2 13.9 15.2 9.9 8.3 2.9 2.2 23.5 13.4 11.0 15.8 5.1 4.5 8.9 13.5 34.2 6.5 7.0 6.1 20.0 17.4 14.9 13.8 8.9 7.2 19.3 11.5 6.6 3.4 9.6 17.0 9.4 3.7 18.7 19.1 8.9 17.7 12.3 7.0 6.3 27.6 14.3 11.9 11.1 12.2 18.5 17.0 6.0 15.8 10.9 10.2 30.9 35.6 33.7 7.2 8.6 7.5 13.7 22.1 36.6 15.3 25.9 15.8 20.8 19.8 19.0 7.5 29.0 16.2 14.6 21.1 16.0 24.6 23.9 32.9 14.8 22.4 24.3 12.9 21.9 21.9 7.7 10.7 23.7 10.3 18.4 12.0 12.6 42.0 33.7 39.3 13.0 15.1 32.1 7.4 18.1 32.4 6.1 17.2 16.8 12.2 8.7 11.4 20.9 20.5 20.5 26.2 16.0 6.6 5.7 0.6 1.2 5.0 0.2 3.3 4.9 3.3 4.7 1.0 2.1 2.3 4.0 0.1 3.2 2.1 2.1 4.6 1.8 3.4 6.9 11.1 3.8 2.9 2.2 5.1 4.5 6.1 3.4 3.7 6.3 10.4 16.0 14.9 148.5 42.5 17.5 16.4 21.0 28.5 33.5 30.8 18.2 55.9 21.5 21.5 51.5 148.0 23.7 37.7 19.7 9.8 15.2 25.5 51.2 11.0 13.3 42.0 40.2 213.7 13.5 10.6 12.8 56.6 61.8 6.3 22.4 10.0 20.5 6.1 30.3 192.6 23.8 24.4 11.1 12.8 5.5 9.6 17.7 16.0 161.1 8.2 17.7 46.4 239.8 217.4 17.2 20.2 10.1 38.3 22.4 22.0 15.8 36.7 72.6 6.6 13.7 9.8 16.6 22.3 37.3 23.7 24.2 45.6 25.9 27.2 24.0 LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007872-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1" "Cell type enhanced" "Detected in many" "Early spermatids: 101.9;Excitatory neurons: 45.4;Spermatocytes: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Group enriched" "Detected in many" 4 "granulocytes: 1.5;NK-cells: 3.8;T-cells: 2.6" "Low cell line specificity" "Detected in all" HPA015135 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" 4.7 3.7 7.5 3.7 6.6 25.1 5.2 13.7 10.3 6.9 0.9 4.9 3.4 6.2 4.7 4.2 6.8 3.6 2.6 8.0 4.2 3.6 2.1 5.6 4.6 4.8 3.4 9.1 3.2 5.7 8.3 3.5 5.2 4.7 4.6 6.9 4.7 2.8 3.5 10.5 5.0 5.2 2.2 6.2 5.0 17.9 5.1 10.9 4.1 1.4 4.5 4.6 5.9 7.1 2.7 5.0 15.6 8.9 3.9 4.7 4.8 2.4 9.0 6.9 8.7 6.8 2.6 7.1 5.0 5.5 8.5 3.6 9.3 1.9 5.4 2.2 7.6 3.4 8.1 2.6 5.8 13.3 5.8 5.1 5.9 6.3 15.9 6.6 5.9 12.1 8.2 6.8 2.6 2.5 23.4 20.5 4.8 2.5 3.3 16.2 3.7 5.9 3.9 6.6 2.9 5.0 6.1 3.8 8.8 5.2 10.4 20.9 5.0 4.8 3.2 10.8 6.1 6.8 10.4 7.5 3.4 13.2 3.4 0.0 0.2 1.5 0.5 0.2 1.0 0.1 1.0 1.4 0.4 0.4 1.4 0.4 0.5 3.8 0.1 0.6 2.6 0.3 7.5 6.6 13.7 10.3 8.0 4.2 4.8 3.4 5.2 2.2 5.1 7.1 7.4 6.4 9.1 39.2 5.1 4.1 6.9 3.8 2.8 10.0 7.3 5.6 4.7 7.2 7.1 1.8 0.0 2.3 10.0 2.9 9.8 8.9 101.9 7.9 6.3 6.0 1.8 7.4 45.4 10.5 2.3 6.0 1.5 4.7 3.8 7.0 8.2 2.9 9.7 3.3 33.4 5.7 4.1 8.7 6.9 22.9 6.8 7.9 8.8 14.0 9.3 14.5 20.6 39.7 28.3 9.2 1.8 7.2 3.8 9.1 6.8 8.3 7.8 9.7 0.0 8.9 7.8 66.7 13.0 1.6 5.1 2.2 9.0 4.6 4.8 7.7 LRRC55 FLJ45686 ENSG00000183908 "Leucine rich repeat containing 55" Q6ZSA7 11 57181747-57191717 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 15.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 2.1;Excitatory neurons: 1.9;Inhibitory neurons: 1.2" "Group enriched" "Detected in some" 9 "glioma: 9.0;ovarian cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AF22: 19.4" "Region enhanced" "Detected in all" "olfactory bulb: 105.4" "Low region specificity" "Detected in all" HPA014053 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014053: AB_2137630" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (3.68e-2)" "unprognostic (3.03e-2)" "unprognostic (2.78e-3)" "unprognostic (2.29e-3)" "unprognostic (2.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (9.43e-2)" "unprognostic (2.11e-2)" "unprognostic (3.32e-2)" "unprognostic (7.17e-4)" "unprognostic (6.66e-2)" "unprognostic (3.59e-1)" "unprognostic (3.79e-2)" 0.4 0.5 4.7 1.0 2.8 0.0 0.1 0.8 3.5 0.1 0.0 0.5 0.3 1.8 0.0 0.0 0.3 0.2 0.3 4.1 6.7 0.3 1.2 0.2 2.1 15.0 11.7 0.0 0.2 0.0 0.0 0.9 3.7 0.0 0.5 0.1 0.6 0.0 0.3 0.1 0.4 1.0 8.4 1.3 0.1 0.2 5.9 0.9 0.1 0.3 0.5 0.0 0.0 6.8 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 2.8 0.8 3.5 4.1 6.7 15.0 11.7 3.7 8.4 5.9 6.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRRC8D "FLJ10470, LRRC5" ENSG00000171492 "Leucine rich repeat containing 8 VRAC subunit D" Q7L1W4 1 89821014-89936611 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 80.8;Oligodendrocyte precursor cells: 146.8;Oligodendrocytes: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.92e-3)" "unprognostic (9.50e-2)" "unprognostic (1.06e-3)" "prognostic unfavorable (3.21e-5)" "unprognostic (4.98e-2)" "unprognostic (7.03e-2)" "unprognostic (7.71e-3)" "unprognostic (7.74e-2)" "unprognostic (9.67e-2)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (4.91e-2)" "unprognostic (9.52e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-2)" "unprognostic (9.61e-2)" 5.9 26.9 25.1 15.8 45.2 14.2 12.9 39.2 37.0 12.1 9.6 17.9 19.0 8.8 10.3 7.9 7.8 8.0 7.6 30.6 30.2 25.9 23.5 9.8 24.9 43.3 40.3 5.9 13.0 7.7 16.3 10.3 41.3 5.6 18.2 12.0 24.5 5.8 8.7 5.6 18.0 11.4 39.7 23.9 11.5 10.3 36.5 27.7 15.8 3.4 20.4 11.2 3.3 80.4 73.5 47.0 18.8 44.5 32.9 27.7 63.5 49.1 73.9 27.3 34.1 20.2 18.3 57.7 54.4 82.1 31.0 93.7 43.6 58.9 34.4 45.3 24.1 67.8 40.4 43.2 64.2 78.2 20.5 17.4 48.1 23.3 50.3 37.6 47.1 32.8 37.6 17.7 30.1 22.0 32.5 50.4 32.6 16.4 42.6 43.6 27.3 41.5 69.2 25.7 35.0 24.4 61.0 62.4 137.8 32.4 15.0 76.4 21.0 29.1 9.9 60.0 37.6 21.4 39.5 34.7 11.3 97.0 26.2 0.0 8.9 1.6 7.0 10.4 11.6 6.9 16.0 8.5 8.1 5.6 15.2 11.5 3.5 13.1 8.4 9.4 17.4 10.6 25.1 45.2 39.2 37.0 30.6 30.2 43.3 40.3 41.3 39.7 36.5 80.4 2.9 3.2 1.7 35.3 10.8 6.0 1.4 12.7 15.9 6.6 8.4 7.4 3.0 8.6 6.2 12.9 2.1 4.0 14.8 26.6 7.9 5.7 0.7 3.1 2.9 5.5 7.8 17.0 66.8 8.6 9.9 3.8 6.1 3.4 5.7 7.8 7.9 30.1 11.8 3.3 80.8 10.8 10.2 21.9 5.5 0.8 1.2 19.1 10.6 68.4 36.3 6.3 10.3 146.8 346.4 5.4 11.3 3.8 8.0 4.1 22.5 12.5 7.2 7.6 6.6 10.7 2.9 0.3 1.9 7.1 1.1 1.8 11.0 22.4 11.2 1.8 LRRC8E FLJ23420 ENSG00000171017 "Leucine rich repeat containing 8 VRAC subunit E" Q6NSJ5 19 7888505-7902021 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9.6;Glandular and luminal cells: 13.0;Squamous epithelial cells: 11.6;Suprabasal keratinocytes: 11.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 36.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020466 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "HPA020466: AB_1853352" "unprognostic (3.79e-2)" "unprognostic (2.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-3)" "unprognostic (8.28e-3)" "unprognostic (7.64e-2)" "unprognostic (1.71e-2)" "unprognostic (3.36e-1)" "unprognostic (8.38e-2)" "unprognostic (3.98e-6)" "unprognostic (1.11e-1)" "unprognostic (2.30e-2)" "unprognostic (3.29e-2)" "unprognostic (3.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-1)" 0.6 4.9 0.4 0.8 0.5 1.9 4.6 1.0 0.6 3.3 0.6 1.0 0.9 1.4 6.2 6.4 2.1 2.3 0.9 0.5 0.1 1.9 4.1 4.3 0.7 0.4 0.2 0.3 7.2 3.3 0.5 1.3 0.7 3.5 1.1 0.4 7.7 2.1 0.5 10.6 0.5 0.4 0.0 0.3 3.6 0.7 0.3 0.1 2.0 0.4 2.8 2.9 4.7 1.4 23.5 6.0 0.2 0.6 1.1 5.6 3.5 10.1 8.7 15.8 12.3 7.7 5.3 0.6 7.5 9.8 22.5 18.3 7.7 9.8 14.9 0.4 8.5 0.3 3.1 8.2 4.1 0.3 0.5 9.1 13.9 10.5 7.8 21.2 2.0 4.1 6.5 0.8 1.9 11.9 0.1 0.5 1.7 4.3 21.9 1.4 0.2 0.6 12.0 21.3 0.5 0.4 7.6 9.6 0.3 1.7 12.8 0.5 2.6 4.8 8.7 13.2 5.8 1.5 2.9 0.3 36.4 0.8 1.7 1.7 0.4 0.5 0.5 0.3 0.6 0.6 0.4 0.4 0.1 0.8 0.5 0.6 1.5 1.1 0.4 0.5 0.4 0.2 0.4 0.5 1.0 0.6 0.5 0.1 0.4 0.2 0.7 0.0 0.3 1.4 0.1 3.2 5.5 0.0 0.1 9.6 5.0 1.5 6.2 0.0 8.2 5.7 0.2 1.5 5.4 1.8 0.0 0.7 0.0 1.1 0.0 6.2 0.0 7.7 2.4 0.5 0.0 0.0 0.1 6.0 1.0 1.0 3.6 13.0 1.3 0.4 0.0 3.2 0.1 0.0 0.1 1.2 4.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.0 5.0 0.1 0.5 6.5 0.0 0.0 0.8 0.9 0.0 0.3 11.6 11.2 1.9 0.5 0.1 1.3 5.9 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.1;skin 1: 110.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 45.5;Macrophages: 28.0;Suprabasal keratinocytes: 47.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 100.3" "Group enriched" "Detected in many" 6 "granulocytes: 100.3;monocytes: 38.4" "Cell line enhanced" "Detected in many" "HaCaT: 20.3;Karpas-707: 17.4" "Low region specificity" "Detected in single" HPA003873 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA003873: AB_1078288" "unprognostic (4.07e-2)" "unprognostic (7.67e-2)" "unprognostic (3.67e-3)" "unprognostic (2.40e-3)" "unprognostic (4.90e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "prognostic favorable (1.85e-4)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (2.88e-1)" "unprognostic (2.97e-1)" "unprognostic (6.59e-2)" "unprognostic (7.45e-2)" 12.5 12.5 1.3 5.0 1.4 16.0 11.8 1.6 1.4 33.3 1.5 6.2 4.2 6.6 5.3 103.1 10.4 2.2 5.4 1.2 1.3 10.3 18.0 15.4 5.4 1.6 1.4 8.4 7.7 0.5 10.8 2.2 1.6 16.8 1.6 4.2 23.5 2.2 5.8 110.1 12.2 1.6 1.5 40.7 6.0 7.8 1.8 4.0 10.2 0.7 9.2 6.8 51.5 1.6 2.7 5.7 2.0 1.6 1.3 1.3 8.4 1.1 0.8 1.2 1.4 4.2 3.2 4.2 1.9 1.1 2.1 20.3 1.8 3.1 1.7 11.5 6.3 4.0 8.4 2.9 0.6 5.7 5.9 0.7 5.5 2.3 3.0 1.8 2.0 6.8 3.7 17.4 0.5 5.6 2.5 10.1 1.4 0.2 4.3 9.9 1.8 7.4 0.7 4.3 4.3 1.7 5.3 2.9 3.0 3.5 4.9 6.2 1.3 4.3 4.2 4.2 1.5 9.9 2.3 7.1 0.9 14.9 2.8 17.0 38.4 40.5 3.4 4.9 2.4 0.0 2.5 2.7 11.2 0.2 1.2 0.8 100.3 2.1 1.2 1.1 0.6 13.7 1.3 1.4 1.6 1.4 1.2 1.3 1.6 1.4 1.6 1.5 1.8 1.6 10.1 0.0 0.6 3.6 2.5 24.0 10.5 18.5 12.0 3.0 6.3 5.0 1.4 5.7 4.3 0.0 6.2 0.9 14.2 2.2 0.0 2.1 0.3 4.6 1.8 5.6 0.0 1.3 1.5 6.1 0.8 2.5 3.1 4.5 1.3 1.4 7.9 4.1 15.6 0.0 1.3 2.8 8.2 45.5 3.7 1.1 3.4 28.0 3.6 2.8 25.4 1.6 18.6 1.0 1.2 4.6 5.4 1.5 6.2 2.7 5.4 0.9 6.4 10.8 6.6 2.0 1.8 1.5 1.4 22.6 47.0 0.8 13.5 1.3 3.2 2.5 LTC4S MGC33147 ENSG00000213316 "Leukotriene C4 synthase" Q16873 5 179793980-179796647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid biosynthesis, Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "granulocytes: 327.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 20.2;eosinophil: 63.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 63.1" "Cell line enriched" "Detected in some" 11 "HMC-1: 102.0" "Low region specificity" "Detected in many" HPA044688 Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Endoplasmic reticulum, Cytosol" "HPA044688: " "unprognostic (8.94e-2)" "unprognostic (2.40e-2)" "unprognostic (9.35e-3)" "unprognostic (3.57e-2)" "unprognostic (1.24e-2)" "unprognostic (9.40e-2)" "unprognostic (4.53e-5)" "unprognostic (2.27e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (1.98e-2)" "unprognostic (4.62e-1)" 8.9 6.9 1.1 0.5 0.8 2.3 5.5 1.5 1.3 4.2 0.7 3.3 0.7 5.7 0.0 3.1 11.8 0.3 12.4 1.0 1.4 7.1 1.9 7.7 0.2 2.1 1.5 5.7 2.0 0.2 3.5 0.4 1.4 4.8 0.2 0.0 4.3 0.8 1.0 3.1 3.2 0.4 2.9 6.1 3.0 1.5 2.6 0.0 5.9 0.0 0.1 4.8 4.0 4.7 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.9 8.9 0.2 0.4 0.3 0.6 102.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.2 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 1.0 0.1 20.2 0.5 63.1 0.8 0.6 3.0 0.3 2.1 1.5 8.6 0.2 0.4 1.0 0.3 4.7 0.0 0.4 0.2 0.6 1.1 0.8 1.5 1.3 1.0 1.4 2.1 1.5 1.4 2.9 2.6 4.7 32.3 0.0 3.2 2.9 2.3 9.9 9.6 11.2 14.8 0.4 26.4 38.6 0.0 14.3 6.2 14.7 0.0 10.4 5.0 0.6 1.9 5.9 0.3 4.0 1.5 49.5 3.0 2.1 0.8 2.4 1.9 8.3 3.1 5.6 327.4 0.5 72.1 0.9 41.5 0.0 0.7 1.7 0.0 20.8 46.3 0.9 16.4 53.9 1.8 28.1 2.0 0.1 2.1 1.0 1.5 1.9 0.5 47.4 10.0 3.7 2.2 54.8 5.8 0.5 0.0 0.8 1.6 0.1 0.7 5.2 7.0 3.0 10.0 1.5 3.1 10.0 LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 213.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB034164: AB_2180094, HPA029143: AB_10671360, HPA055604: AB_2682859" "unprognostic (3.67e-2)" "unprognostic (7.07e-2)" "unprognostic (7.78e-2)" "unprognostic (3.99e-1)" "unprognostic (1.42e-2)" "unprognostic (3.66e-3)" "unprognostic (5.38e-2)" "unprognostic (5.40e-2)" "unprognostic (9.98e-2)" "unprognostic (4.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (9.87e-2)" "unprognostic (1.72e-1)" "unprognostic (8.22e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" 7.7 8.4 4.5 9.3 7.8 16.5 12.4 7.0 6.2 9.3 5.3 9.2 8.8 10.7 10.2 9.1 7.0 7.4 7.7 4.1 6.6 8.3 11.0 7.4 12.0 6.1 5.9 10.1 9.4 9.9 3.9 18.6 6.7 12.7 10.6 11.6 10.1 8.1 9.5 9.4 9.0 9.1 6.2 10.3 11.0 13.6 6.1 11.3 12.1 11.2 10.5 8.3 5.9 13.1 20.4 8.6 17.5 7.9 14.6 19.9 17.7 16.8 13.6 14.2 19.4 12.1 16.5 13.3 8.0 15.1 12.2 10.2 18.8 13.8 25.5 15.7 13.0 39.8 11.9 9.7 11.0 13.3 14.8 13.9 12.1 20.1 16.6 13.9 15.2 9.5 33.0 31.0 16.4 6.3 8.6 12.9 25.1 16.8 10.1 11.4 34.9 28.0 16.0 17.3 9.5 19.7 19.3 14.5 17.0 16.3 14.8 18.6 20.2 12.4 22.9 16.8 14.3 25.1 25.1 18.5 19.3 28.3 15.0 12.6 4.9 7.9 6.3 7.6 5.2 5.8 4.2 4.2 4.9 5.1 4.5 3.4 8.6 7.0 10.7 3.1 5.0 2.6 4.5 7.8 7.0 6.2 4.1 6.6 6.1 5.9 6.7 6.2 6.1 13.1 42.1 16.0 22.6 36.6 30.7 30.2 26.3 22.8 30.7 28.4 22.8 17.4 25.8 12.8 24.0 11.0 33.3 19.3 26.8 18.4 1.9 14.4 213.7 21.6 45.9 27.5 22.7 18.7 47.1 14.0 18.8 30.3 38.2 36.2 27.8 24.2 14.3 19.7 13.2 42.1 54.8 18.9 22.4 18.1 13.2 73.1 26.8 23.5 12.4 25.3 28.2 44.9 18.6 53.8 90.8 20.2 14.2 21.1 43.9 31.5 16.6 16.9 22.6 30.5 13.1 29.3 28.6 46.8 23.9 30.1 32.0 29.8 30.5 34.3 20.8 29.8 LY6G6F-LY6G6D "G6F-LY6G6D, MEGT-1, MEGT1" ENSG00000250641 "LY6G6F-LY6G6D readthrough" 6 31706904-31717918 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "skin 1: 5.4;testis: 2.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008053 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "HPA008053: AB_1840160" "unprognostic (5.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.47e-1)" "unprognostic (5.90e-2)" "unprognostic (1.07e-2)" "unprognostic (2.66e-1)" "unprognostic (2.42e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MADD "DENN, KIAA0358, RAB3GEP" ENSG00000110514 "MAP kinase activating death domain" Q8WXG6 11 47269161-47330031 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 133.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 80.9;Cone photoreceptor cells: 125.1;Horizontal cells: 132.9;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 33.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 33.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038568 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA038568: AB_10795030" "unprognostic (3.16e-1)" "unprognostic (1.81e-1)" "unprognostic (8.51e-3)" "prognostic favorable (6.62e-5)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (4.82e-3)" "unprognostic (1.16e-1)" "unprognostic (1.91e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.69e-5)" "unprognostic (1.53e-1)" "unprognostic (3.55e-1)" "unprognostic (8.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" "prognostic favorable (8.25e-4)" 15.1 24.6 32.4 17.7 32.2 28.4 14.8 46.7 44.5 16.1 0.3 17.9 12.4 15.1 12.0 11.1 14.0 12.2 24.6 40.5 21.2 17.1 13.0 19.0 20.9 18.2 18.8 18.8 17.5 18.4 65.7 16.0 22.1 20.7 16.6 133.2 16.6 17.1 30.1 22.8 19.0 14.6 7.0 22.0 18.8 28.5 16.7 23.6 14.4 23.4 17.9 18.7 15.0 32.1 14.0 28.7 30.8 27.6 20.6 14.3 6.9 19.3 25.8 24.2 25.9 21.0 12.9 29.6 6.0 21.3 31.1 27.2 25.2 13.6 20.8 33.1 25.6 52.7 55.0 18.3 14.8 36.1 69.4 13.9 14.3 12.7 15.9 16.4 22.4 18.7 34.5 21.1 21.5 19.7 17.2 38.6 18.4 32.8 19.6 23.2 49.5 19.7 12.4 66.0 48.4 31.5 24.9 29.0 17.6 18.1 22.8 27.0 19.2 22.4 14.1 32.3 13.2 24.9 27.9 16.6 20.9 25.1 21.5 33.3 3.4 6.5 5.6 5.6 5.0 4.0 3.9 4.6 5.2 4.2 4.5 3.6 0.9 5.7 7.9 2.7 7.5 6.2 32.4 32.2 46.7 44.5 40.5 21.2 18.2 18.8 22.1 7.0 16.7 32.1 10.6 12.8 9.2 21.5 11.7 10.7 4.1 6.1 6.8 80.9 11.3 10.2 23.4 7.2 5.8 7.3 125.1 4.6 29.0 21.2 0.0 7.5 14.6 5.3 7.0 11.5 16.3 8.6 37.4 4.9 2.3 7.8 23.4 8.3 26.6 13.9 14.6 7.0 11.5 132.9 33.7 17.7 4.1 19.4 14.9 4.9 7.2 14.9 10.6 21.5 11.1 14.4 23.7 14.1 22.4 12.0 12.2 12.8 17.7 8.0 12.2 5.1 6.2 106.8 6.6 8.7 7.7 14.9 23.2 6.7 8.2 4.4 15.4 16.2 13.7 5.9 MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 373.3;Distal tubular cells: 236.7;Muller glia cells: 91.5;Oligodendrocytes: 168.1;Skeletal myocytes: 82.3;Squamous epithelial cells: 90.9" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cell line enhanced" "Detected in some" "HDLM-2: 516.4;MOLT-4: 722.0;RPMI-8226: 256.7;RPTEC TERT1: 2531.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" 5.3 1.8 251.3 10.8 333.9 12.7 4.4 264.8 400.2 450.7 177.4 50.8 2.2 2.6 8.3 2817.9 8.9 2.9 17.9 260.8 256.7 400.4 1.7 25.3 25.1 281.3 282.1 3.2 3.0 0.4 3.9 3.4 272.9 21.8 6.3 10.1 544.0 11.1 2.8 12.6 17.0 2.4 264.0 9.4 52.7 1.1 303.2 261.2 21.3 4.3 352.8 15.0 863.2 449.3 51.3 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 12.0 0.0 0.3 2.4 0.2 0.0 0.5 516.4 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.4 0.1 0.1 0.0 722.0 0.2 0.2 0.0 0.0 0.7 0.0 256.7 2531.4 65.3 0.6 0.0 0.1 9.4 1.6 2.1 0.3 0.9 0.8 0.0 0.2 0.1 0.5 0.4 0.3 0.3 0.3 0.4 0.1 0.7 0.6 0.1 4.7 0.3 2.1 3.1 217.6 38.4 0.5 3.5 293.3 138.1 2.6 7.7 0.6 1.2 233.6 71.0 251.3 333.9 264.8 400.2 260.8 256.7 281.3 282.1 272.9 264.0 303.2 449.3 0.9 0.0 0.0 12.1 3.1 1.1 0.2 0.0 1.8 1.5 1.2 0.9 11.3 0.0 1.3 373.3 4.2 0.2 0.9 0.0 236.7 0.1 5.3 4.3 0.6 0.5 0.0 46.1 0.5 0.0 0.0 4.7 24.5 8.2 1.3 3.2 2.5 0.0 0.1 5.0 0.5 0.0 14.2 0.0 1.3 19.5 0.9 1.0 17.8 1.9 2.5 91.5 4.1 6.6 168.1 0.1 0.0 0.0 8.9 0.2 0.0 3.2 0.0 2.7 6.6 82.3 5.3 0.0 0.6 90.9 1.0 0.3 35.8 0.0 0.1 0.8 MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 389.9;Distal enterocytes: 433.3;Pancreatic endocrine cells: 329.8;Suprabasal keratinocytes: 455.8;Urothelial cells: 594.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1042.5;HaCaT: 451.8;OE19: 1132.4;RPTEC TERT1: 385.4;SK-BR-3: 1439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" 14.1 1.8 8.5 10.6 13.4 0.0 65.6 15.3 28.0 41.9 0.0 102.9 64.3 6.7 14.2 259.2 54.4 33.1 2.1 22.2 17.0 85.7 47.0 81.6 1.3 0.0 4.2 0.5 37.4 43.5 35.8 12.0 0.0 26.9 94.2 2.6 62.6 41.2 0.4 121.0 53.0 2.6 0.0 0.4 137.6 12.5 8.3 4.3 147.5 0.1 56.0 69.0 102.6 3.4 1042.5 0.0 1.0 0.3 0.2 0.0 92.9 0.1 2.3 1.2 1.6 87.7 329.0 0.3 56.2 0.0 0.4 451.8 0.8 32.9 0.5 0.9 2.6 0.0 13.8 86.1 0.3 0.6 0.3 0.0 225.5 0.0 34.3 1.7 0.3 0.0 0.2 0.5 0.0 244.9 0.8 0.3 8.2 1132.4 309.2 0.6 0.0 0.7 385.4 257.4 56.7 0.3 17.8 1439.4 2.7 6.8 191.4 3.0 0.0 0.6 3.1 1.3 1.9 5.5 0.8 1.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 13.4 15.3 28.0 22.2 17.0 0.0 4.2 0.0 0.0 8.3 3.4 0.5 112.2 130.8 4.2 2.7 114.7 79.9 59.3 19.9 1.5 118.9 50.7 1.6 90.1 119.7 389.9 0.0 25.0 0.4 433.3 109.5 206.0 0.5 71.8 10.3 3.7 41.9 0.0 62.4 178.6 23.5 4.7 149.9 139.4 14.7 0.0 3.6 44.9 2.9 5.0 9.8 145.9 71.2 0.3 14.3 2.2 0.6 2.3 16.0 3.7 3.6 1.0 0.0 3.5 3.6 329.8 252.9 0.0 1.2 285.4 70.2 19.9 107.5 1.0 0.0 0.0 7.0 1.9 9.7 268.8 455.8 9.3 2.8 0.0 122.5 594.5 MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.6;retina: 27.5" "Group enriched" "Detected in some" 4 "B-cells: 21.4;Hofbauer cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.3;myeloid DC: 44.2;naive B-cell: 35.8;non-classical monocyte: 45.4;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 7.1;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: AB_1853573, HPA048024: " "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 6.4 3.5 7.8 21.5 8.1 3.9 2.7 3.6 7.7 3.1 1.8 3.5 3.9 2.5 0.7 3.0 2.8 5.3 1.7 6.6 10.1 1.8 4.1 8.0 31.6 8.0 8.2 2.7 2.8 0.8 2.5 9.9 6.9 2.3 4.5 27.5 3.2 1.2 1.0 4.5 7.0 6.2 7.0 25.8 3.9 1.7 12.1 5.6 2.1 1.0 25.5 7.7 2.9 14.4 0.6 0.5 2.1 1.2 0.0 0.0 1.3 0.9 0.0 0.0 0.0 1.2 2.4 7.1 2.5 0.0 0.2 1.0 0.0 0.0 0.0 0.8 0.7 5.0 3.0 0.5 0.0 3.1 1.6 0.0 0.0 0.0 0.1 2.8 0.0 1.3 1.9 3.6 2.4 0.7 1.8 1.9 2.6 0.2 0.9 2.0 0.3 0.5 0.1 1.1 1.0 0.9 0.6 1.0 0.4 1.4 2.9 0.5 2.3 0.8 1.4 0.5 1.7 7.0 2.5 1.9 0.9 1.5 1.1 0.0 41.8 25.5 0.1 41.0 0.0 42.3 0.1 0.0 44.2 35.8 0.0 0.0 0.3 0.3 45.4 16.5 0.0 18.4 7.8 8.1 3.6 7.7 6.6 10.1 8.0 8.2 6.9 7.0 12.1 14.4 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 MARCHF11 "MARCH-XI, MARCH11, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 82.4" "Cell type enriched" "Detected in single" 30 "Cardiomyocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 83.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (9.91e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" 0.1 0.7 4.7 0.0 4.6 0.0 0.3 5.0 6.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.7 6.7 0.2 0.1 0.0 0.0 5.7 4.7 0.3 1.3 0.0 9.9 0.0 5.0 0.3 0.0 3.6 1.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.1 82.4 4.8 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 83.8 0.0 0.0 0.0 7.5 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.6 5.0 6.7 5.7 6.7 5.7 4.7 5.0 3.8 4.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MARCHF2 "HSPC240, MARCH-II, MARCH2, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.1;Cardiomyocytes: 42.3;Extravillous trophoblasts: 11.6;Hofbauer cells: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.48e-4)" "prognostic favorable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favorable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 65.7 33.0 102.2 20.3 101.5 29.4 49.8 99.5 106.6 24.2 66.4 96.2 15.7 34.4 53.9 32.4 27.1 15.3 101.1 90.9 94.3 35.6 59.1 41.9 19.5 113.7 102.5 15.8 19.2 15.3 30.5 19.8 106.0 40.8 14.0 9.1 25.5 28.8 89.5 34.5 31.4 30.1 109.2 51.2 32.9 18.9 105.1 14.2 47.9 48.6 14.5 49.8 26.1 96.7 11.4 14.2 6.3 29.5 37.9 12.6 10.7 12.3 14.7 9.5 9.8 7.0 5.5 4.4 34.8 26.7 12.6 8.1 8.2 17.5 7.3 22.7 20.3 34.2 6.6 15.9 20.5 5.0 49.6 14.7 20.1 9.2 8.1 13.9 38.2 17.8 4.9 24.5 7.5 21.5 7.0 16.7 13.3 14.0 34.2 11.0 2.0 11.4 22.4 13.9 3.1 17.7 0.8 12.9 24.2 21.5 10.2 10.8 38.9 13.3 8.4 44.5 10.4 21.7 28.2 5.0 21.6 10.2 10.7 52.6 18.5 31.3 10.6 28.6 10.8 7.2 10.6 8.6 13.1 7.3 7.2 9.6 23.4 7.9 25.7 51.8 14.9 17.4 102.2 101.5 99.5 106.6 90.9 94.3 113.7 102.5 106.0 109.2 105.1 96.7 23.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 8.1 9.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 11.6 7.7 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 5.7 1.5 0.0 0.0 0.0 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 4.4;pituitary gland: 6.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 69.0;fHDF/TERT166: 43.8;TIME: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.0 0.7 2.6 0.0 3.9 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 3.1 2.2 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.4 0.0 6.2 0.6 1.1 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.0 2.7 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 12.5 2.5 0.0 0.0 0.2 1.6 0.0 69.0 23.2 14.5 5.1 0.1 1.0 0.0 10.5 43.8 24.2 0.1 0.0 26.7 14.1 0.0 0.0 5.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 13.3 19.6 9.3 19.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.4 1.9 0.1 0.0 0.0 2.2 0.0 0.0 32.7 22.7 23.9 0.1 18.6 0.0 0.0 0.0 5.2 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.9 0.0 4.4 3.1 2.2 0.5 4.1 1.1 2.7 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MARCHF8 "c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favorable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favorable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 14.3 19.2 11.8 12.4 18.5 49.1 16.8 19.3 13.1 13.8 11.7 21.3 14.2 14.4 10.4 10.6 15.3 13.4 20.5 11.1 13.1 15.5 16.9 15.0 16.9 18.8 14.2 19.5 26.5 19.8 16.0 12.2 17.3 11.5 18.3 18.2 14.8 15.2 14.7 10.5 22.4 13.8 14.7 18.7 14.4 57.1 16.1 17.8 16.3 15.4 20.3 11.4 9.0 26.7 16.6 16.4 13.7 12.4 19.4 24.2 10.1 7.5 35.0 13.6 14.8 4.2 16.8 23.8 12.6 21.9 12.3 3.0 15.2 12.4 12.6 36.3 16.7 9.2 7.4 10.0 13.6 11.3 39.1 19.8 16.3 6.8 17.9 13.4 22.5 22.4 26.5 23.2 10.5 5.8 11.5 7.1 4.5 2.4 5.3 12.7 13.7 7.0 10.2 9.5 12.2 17.0 14.7 3.5 14.0 13.3 21.2 5.2 15.1 10.6 13.6 15.6 12.0 39.8 34.2 10.5 21.0 15.5 2.9 13.9 1.1 10.8 3.0 1.9 4.5 3.5 3.4 3.3 1.6 5.4 2.5 3.2 14.1 8.5 0.9 1.6 3.6 2.5 11.8 18.5 19.3 13.1 11.1 13.1 18.8 14.2 17.3 14.7 16.1 26.7 6.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 2.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.0 MARCHF9 "FLJ36578, MARCH9, RNF179" ENSG00000139266 "Membrane associated ring-CH-type finger 9" Q86YJ5 12 57755103-57760411 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 6.0;B-cells: 6.6;Cardiomyocytes: 12.3;dendritic cells: 12.0;Hofbauer cells: 7.3;Plasma cells: 8.3;T-cells: 3.4" "Cancer enriched" "Detected in all" 4 "glioma: 39.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 12 "RH-30: 515.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (2.96e-2)" "unprognostic (6.78e-2)" "unprognostic (1.90e-3)" "prognostic favorable (3.07e-4)" "unprognostic (2.16e-1)" "unprognostic (6.85e-2)" "unprognostic (8.15e-3)" "prognostic favorable (1.54e-5)" "unprognostic (7.76e-2)" "prognostic favorable (1.59e-4)" "unprognostic (1.08e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.98e-5)" "unprognostic (2.44e-1)" "unprognostic (2.86e-1)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" 8.8 17.6 15.3 7.8 16.0 5.1 10.0 17.7 16.9 11.3 14.5 13.5 7.6 9.0 8.4 12.6 8.4 6.4 17.3 15.6 16.1 28.0 8.6 19.0 13.9 14.8 15.2 8.9 17.4 17.9 34.9 7.7 14.2 16.5 6.5 40.6 14.3 8.5 13.0 17.9 20.0 4.7 14.6 29.0 14.8 5.2 15.5 19.4 25.4 9.0 13.8 9.8 10.0 14.3 15.3 7.5 11.6 12.7 1.2 0.4 15.0 2.3 16.0 8.8 8.5 9.7 12.0 37.3 12.1 0.4 15.2 13.6 19.1 16.3 5.7 22.4 21.1 4.8 5.9 5.0 10.7 4.6 7.5 1.8 16.8 2.5 8.9 26.0 3.8 36.9 6.9 37.1 2.3 14.5 24.3 5.8 7.6 10.8 16.1 19.9 515.3 40.6 17.5 13.4 26.1 17.1 1.1 1.2 10.4 5.6 26.4 9.1 0.3 11.4 9.1 6.5 7.5 41.8 20.4 22.6 12.5 1.1 11.7 2.0 0.4 0.1 3.2 0.6 5.0 4.6 5.1 4.4 1.4 5.8 5.0 3.7 0.2 2.6 0.2 9.8 3.3 1.1 15.3 16.0 17.7 16.9 15.6 16.1 14.8 15.2 14.2 14.6 15.5 14.3 6.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.9 12.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 3.4 0.0 0.0 0.0 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 43.5;epididymis: 13.9;parathyroid gland: 35.3" "Group enriched" "Detected in many" 7 "Enteroendocrine cells: 113.6;Melanocytes: 151.2" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.9;HAP1: 12.7;RH-30: 15.7;SK-MEL-30: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" 3.0 43.5 0.7 0.2 0.2 0.0 2.2 0.0 4.0 5.1 3.3 1.0 5.4 5.7 13.9 0.3 1.7 0.3 4.4 3.5 0.1 5.0 0.1 4.5 0.1 0.0 0.1 2.1 7.4 35.3 7.0 2.5 0.1 0.3 1.0 0.1 3.7 0.6 0.2 4.3 2.2 1.9 0.2 0.9 2.6 0.6 0.5 4.3 1.9 1.1 0.2 0.4 2.4 0.0 9.0 2.0 0.0 0.0 6.6 5.9 2.4 0.1 12.9 3.2 8.8 0.6 1.5 0.0 0.9 0.1 3.0 0.0 12.7 4.2 2.0 3.6 8.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 1.5 2.6 1.5 3.2 0.0 0.0 0.0 0.0 6.3 0.7 0.0 0.0 1.0 0.0 1.1 0.0 15.7 0.0 0.4 0.0 0.5 0.0 0.4 0.0 29.3 0.9 5.2 6.5 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 4.0 3.5 0.1 0.0 0.1 0.1 0.2 0.5 0.0 16.6 16.0 1.7 0.0 0.0 8.7 3.5 7.0 0.6 0.0 4.2 1.9 6.8 11.5 2.5 3.7 0.0 9.0 0.1 0.3 0.0 1.7 0.4 0.8 8.1 2.0 113.6 0.0 1.2 9.6 0.2 18.4 1.5 1.9 0.0 0.3 0.0 0.1 3.5 0.0 0.4 2.5 6.1 0.0 7.1 0.1 1.8 3.2 151.2 2.8 1.6 0.0 0.0 0.0 0.1 3.6 12.9 0.0 0.3 1.4 4.1 3.4 0.7 0.0 6.6 6.3 1.2 1.8 4.1 0.4 3.4 2.6 1.4 1.0 3.8 0.6 MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.3;Excitatory neurons: 510.6;Inhibitory neurons: 412.2;Oligodendrocyte precursor cells: 263.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Cell line enhanced" "Detected in many" "Karpas-707: 71.4;RPMI-8226: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019018 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA019018: AB_1853665" "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" 21.3 2.3 12.8 12.5 37.1 45.3 15.9 27.7 19.4 6.0 0.0 7.7 5.1 5.9 2.0 6.4 4.9 17.4 3.8 20.9 10.0 4.4 3.7 12.9 6.1 3.8 0.5 1.7 3.2 1.9 4.0 7.3 5.7 3.5 7.2 1.7 3.7 2.2 3.2 4.3 4.9 11.2 0.5 8.8 5.5 2.1 1.4 7.9 4.6 7.9 4.4 21.3 6.1 13.4 0.3 5.2 3.3 0.1 49.0 19.6 0.2 0.3 25.1 2.3 8.1 0.1 13.3 18.7 19.2 0.0 51.1 0.2 0.4 0.2 2.8 0.0 3.6 11.4 13.3 0.2 6.4 23.6 14.6 7.3 0.0 9.0 32.5 21.2 52.7 7.6 0.3 71.4 18.7 0.6 1.4 17.9 4.1 0.3 20.7 0.9 0.2 73.7 52.7 29.0 10.0 0.5 1.7 0.1 37.1 1.4 0.0 21.8 0.3 9.0 13.9 0.4 4.2 5.0 0.1 0.2 41.8 38.5 9.1 37.0 28.6 13.2 0.1 41.4 0.0 0.6 0.1 0.2 22.3 0.3 0.4 0.0 40.5 0.3 40.6 11.4 0.0 8.5 12.8 37.1 27.7 19.4 20.9 10.0 3.8 0.5 5.7 0.5 1.4 13.4 113.3 3.2 10.8 15.3 3.2 18.1 0.2 6.9 3.4 2.2 1.7 1.1 3.1 0.0 6.6 3.7 0.0 0.3 9.8 0.1 0.0 0.0 27.8 5.5 1.2 97.9 0.0 5.0 510.6 0.2 0.2 18.5 5.6 11.6 63.3 0.1 2.2 0.3 12.2 3.3 412.2 0.0 4.1 42.4 76.5 16.2 0.6 63.5 12.4 67.5 32.9 3.2 2.1 263.4 9.0 1.3 0.0 0.0 2.4 0.8 0.0 0.5 3.5 3.5 0.0 1.8 2.0 1.8 1.4 0.7 13.4 0.3 3.7 0.3 0.0 0.6 MCTP2 "FLJ11175, FLJ33303" ENSG00000140563 "Multiple C2 and transmembrane domain containing 2" Q6DN12 15 94231538-94483952 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 72.8;NK-cells: 97.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Immune cell enhanced" "Detected in many" "neutrophil: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 20.8;HMC-1: 16.4;U-698: 22.4;U-87 MG: 24.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051176, HPA070541" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA051176: AB_2681373, HPA070541: AB_2686277" "unprognostic (1.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.63e-2)" "unprognostic (7.15e-4)" "unprognostic (3.57e-2)" "unprognostic (2.66e-3)" "unprognostic (3.45e-2)" "unprognostic (3.68e-3)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (5.87e-2)" "unprognostic (4.36e-1)" "unprognostic (1.76e-3)" "unprognostic (9.41e-2)" 4.1 3.8 1.0 6.6 1.8 18.0 2.9 0.0 6.8 5.4 0.8 10.6 6.9 1.8 8.6 3.9 4.1 4.5 0.6 1.1 2.8 2.3 1.5 8.7 6.1 0.0 0.3 1.6 5.7 3.5 7.3 19.3 1.0 5.4 12.2 2.6 5.9 4.1 0.1 3.6 6.4 1.6 0.0 21.1 4.7 1.0 1.3 3.0 5.5 0.4 6.2 6.6 3.7 0.6 3.6 0.0 0.1 0.0 0.0 0.0 2.5 1.9 1.1 0.3 0.1 2.4 4.4 10.3 0.5 0.1 0.1 8.0 0.1 6.6 0.0 2.1 0.8 20.8 2.9 1.2 1.4 4.4 16.4 1.1 7.8 0.1 8.2 0.0 0.0 3.6 0.8 5.9 0.0 0.0 2.0 11.4 0.8 3.6 3.7 4.7 0.1 4.0 0.5 10.7 1.9 0.4 0.2 3.4 1.3 0.8 0.0 0.3 0.2 0.1 1.7 0.0 0.0 12.0 0.3 22.4 24.1 11.1 1.2 6.6 0.8 12.1 6.1 0.2 3.0 3.5 1.7 2.8 0.0 3.6 0.7 2.7 32.1 10.9 0.9 0.3 0.1 1.9 1.0 1.8 0.0 6.8 1.1 2.8 0.0 0.3 1.0 0.0 1.3 0.6 1.1 3.2 18.6 1.0 38.9 4.2 12.9 8.6 22.8 15.6 3.8 4.3 1.1 7.2 13.2 3.7 0.0 17.0 72.8 39.4 0.0 3.4 4.0 6.5 3.4 1.8 15.6 35.7 15.6 4.7 7.3 7.8 5.6 6.6 36.2 0.3 1.4 1.4 9.6 0.0 10.3 43.8 8.2 8.7 2.1 4.8 0.3 11.1 1.8 25.3 4.7 0.1 97.9 0.0 0.7 4.2 24.6 0.0 45.8 14.2 18.1 1.9 8.7 0.6 0.0 2.5 1.6 3.4 2.5 15.0 2.3 24.5 26.6 0.5 21.5 19.6 MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692131-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 53.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 68.3;Inhibitory neurons: 65.6;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favorable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" 6.1 3.8 2.8 7.4 2.5 19.9 5.7 10.4 3.6 8.3 6.4 28.7 27.8 8.9 3.0 14.2 10.8 12.7 7.8 3.9 2.8 10.6 7.0 10.2 4.9 3.4 3.2 4.9 5.5 10.0 1.9 12.8 3.2 5.8 30.8 2.3 6.7 5.7 41.8 6.8 24.5 13.5 3.0 5.0 43.2 4.3 3.3 5.7 6.4 53.7 7.7 14.9 5.1 2.8 41.7 66.1 16.8 12.2 25.0 28.0 17.1 25.0 35.5 24.5 26.0 39.6 38.6 17.7 19.6 30.8 13.3 36.9 22.2 29.8 32.5 19.5 20.8 22.1 23.5 22.1 19.5 56.0 17.9 28.7 24.9 22.0 46.6 38.4 29.8 18.5 14.0 12.9 23.0 24.3 15.2 12.0 18.5 45.2 13.6 15.7 35.8 4.7 32.7 22.4 17.8 7.9 30.8 34.1 7.5 20.2 6.8 14.5 24.3 11.8 19.9 25.7 16.9 9.4 12.8 12.1 15.8 27.5 9.2 1.8 6.7 18.6 3.0 7.3 3.1 3.5 2.9 3.6 5.8 1.7 2.3 2.6 8.8 2.2 8.9 2.0 5.2 4.2 2.8 2.5 10.4 3.6 3.9 2.8 3.4 3.2 3.2 3.0 3.3 2.8 13.7 35.3 17.0 21.2 4.2 11.7 14.4 8.9 10.8 3.0 5.9 3.9 6.6 8.6 22.0 18.4 2.1 7.3 4.8 38.2 1.9 11.1 14.5 23.3 9.9 9.7 8.4 10.8 58.2 25.2 10.1 7.2 68.3 26.4 8.2 3.4 8.9 5.8 6.7 0.0 65.6 28.2 12.2 6.0 2.9 7.2 5.3 6.7 8.8 37.5 5.7 5.4 2.1 72.4 40.3 40.7 15.6 4.1 5.7 9.7 19.8 8.6 22.6 3.9 13.1 6.8 12.1 5.1 5.2 6.2 12.4 9.3 5.0 12.7 24.5 26.8 MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 127.7;Exocrine glandular cells: 111.4;Extravillous trophoblasts: 91.9;Hofbauer cells: 106.8;Pancreatic endocrine cells: 67.9;Syncytiotrophoblasts: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 93.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048776 Enhanced Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Vesicles, Mitochondria" "HPA048776: AB_2680518" "unprognostic (6.12e-3)" "unprognostic (1.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-3)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.35e-6)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" 10.2 2.0 2.6 18.4 3.0 10.6 7.6 2.1 3.4 7.0 3.5 5.3 3.8 8.8 1.5 6.8 5.8 7.8 10.5 2.7 4.6 3.5 2.2 7.2 32.2 4.3 3.0 5.6 1.5 1.2 3.7 6.1 3.2 3.0 6.3 3.7 4.9 2.1 1.4 6.2 7.8 8.2 3.7 13.5 4.6 3.0 5.2 31.4 3.3 3.5 25.7 9.2 7.5 4.6 26.9 11.7 6.4 32.6 6.9 18.1 23.9 23.3 14.2 24.9 22.1 0.6 21.6 93.0 4.6 20.2 13.8 7.6 24.1 14.0 21.9 59.2 18.4 11.3 11.6 1.6 12.1 23.6 0.4 11.7 3.8 15.1 13.0 17.7 33.9 35.0 3.3 59.4 19.2 34.0 54.1 0.4 28.2 4.8 15.6 20.4 47.7 10.8 29.6 12.1 25.6 11.1 24.2 73.4 7.7 5.3 9.2 1.2 23.9 9.8 12.6 51.8 40.2 22.3 16.4 22.7 29.9 4.9 6.9 0.4 51.4 0.8 18.9 32.2 26.6 43.6 79.1 56.5 49.8 50.7 114.7 66.2 3.6 65.0 24.4 35.1 74.9 92.2 2.6 3.0 2.1 3.4 2.7 4.6 4.3 3.0 3.2 3.7 5.2 4.6 21.5 9.6 5.2 0.0 19.5 0.0 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.0 2.5 5.5 0.0 127.7 36.0 0.0 0.0 25.2 0.0 7.0 5.9 11.7 0.0 0.0 0.0 111.4 91.9 15.1 0.0 8.9 1.3 9.1 0.0 0.0 106.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 14.5 0.0 0.0 0.0 0.0 67.9 0.0 0.0 5.8 0.0 0.0 0.9 2.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 73.5 28.2 7.4 0.0 0.0 MDGA2 MAMDC1 ENSG00000139915 "MAM domain containing glycosylphosphatidylinositol anchor 2" Q7Z553 14 46839629-47675605 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 8.0;retina: 4.4;testis: 3.8" "Group enriched" "Detected in some" 7 "Excitatory neurons: 1559.3;Inhibitory neurons: 1208.8;Oligodendrocyte precursor cells: 1972.9" "Cancer enhanced" "Detected in single" "melanoma: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.1;T-47d: 2.5;U-138 MG: 5.6;U-2 OS: 4.0;U-87 MG: 2.1;WM-115: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003084 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA003084: AB_1079302" "unprognostic (3.27e-1)" "unprognostic (5.38e-2)" "unprognostic (9.13e-2)" "unprognostic (8.92e-3)" "unprognostic (6.36e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.49e-3)" "unprognostic (3.62e-3)" "unprognostic (3.06e-2)" "unprognostic (5.89e-1)" 0.1 0.2 5.4 0.0 6.3 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 6.4 0.1 0.1 0.0 0.0 7.0 2.7 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 4.4 0.1 0.0 0.0 0.3 0.0 0.0 4.9 0.0 0.2 3.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 2.5 0.0 0.0 5.6 4.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 6.3 0.1 6.1 6.1 6.4 7.0 2.7 8.0 4.9 3.1 5.1 0.0 0.0 0.0 24.2 0.1 0.4 0.0 0.0 0.0 50.6 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 50.9 0.0 0.0 0.1 0.0 0.0 1559.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1208.8 0.0 0.0 0.0 0.0 7.1 0.3 0.0 5.4 52.5 0.0 0.3 0.0 1972.9 209.4 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.2 4.4 6.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 MED24 "CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100" ENSG00000008838 "Mediator complex subunit 24" O75448 17 40019097-40061215 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 178.1;Club cells: 100.6;Ionocytes: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 244.1;SK-BR-3: 283.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.93e-2)" "unprognostic (1.65e-1)" "unprognostic (4.10e-2)" "unprognostic (8.27e-2)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.56e-1)" "unprognostic (1.33e-1)" "unprognostic (1.19e-2)" "unprognostic (4.04e-2)" "unprognostic (3.18e-3)" "unprognostic (4.36e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (3.97e-1)" 28.4 30.6 21.6 24.8 23.0 37.3 29.1 20.7 29.2 37.8 18.3 29.5 28.6 33.9 19.0 32.6 31.8 16.8 35.3 24.2 19.0 29.1 25.7 46.5 26.7 18.3 21.2 38.8 25.6 31.2 39.1 23.8 19.5 28.1 24.5 26.4 31.4 17.9 84.0 35.2 30.1 24.3 16.9 30.1 30.5 35.8 19.3 32.7 28.9 48.9 27.9 25.8 30.1 19.6 31.8 63.3 57.3 59.1 38.7 36.1 44.6 41.7 32.5 56.7 50.4 63.1 42.2 65.0 71.6 46.5 28.2 72.8 89.7 244.1 45.3 59.8 147.2 34.0 59.2 84.0 32.2 84.4 63.0 45.0 45.5 56.3 34.1 36.8 75.0 42.8 98.1 41.9 38.6 42.1 93.7 55.2 37.7 36.7 72.4 71.2 45.2 54.5 29.7 36.5 79.9 57.8 43.9 283.0 33.4 49.3 62.4 75.4 45.2 31.1 26.0 34.5 53.6 39.0 41.4 49.5 56.5 42.2 42.7 0.5 4.8 6.0 5.3 6.0 4.2 4.6 3.7 6.1 6.8 4.0 3.5 4.2 0.3 3.5 3.9 2.8 3.9 5.1 21.6 23.0 20.7 29.2 24.2 19.0 18.3 21.2 19.5 16.9 19.3 19.6 14.9 22.4 51.3 13.1 12.7 11.3 25.1 178.1 13.1 11.9 31.4 24.9 16.3 20.0 100.6 23.9 16.7 28.9 8.3 24.8 15.6 15.1 14.8 20.6 10.2 43.3 28.1 27.0 17.6 18.0 23.3 12.2 42.3 27.0 10.8 28.5 9.3 14.8 20.0 10.1 20.3 34.1 99.7 12.0 19.2 8.6 9.9 8.6 14.2 9.4 15.4 10.8 6.2 13.6 13.9 18.5 43.7 9.4 14.2 10.4 23.7 17.6 66.3 11.5 6.6 10.9 13.5 13.4 15.5 12.0 18.6 22.6 10.7 18.0 33.3 28.6 METTL21A "FAM119A, HCA557b, HSPA-KMT, LOC151194" ENSG00000144401 "Methyltransferase like 21A" Q8WXB1 2 207580631-207625928 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Paneth cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "HPA034712: AB_10670160" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (4.56e-2)" "unprognostic (2.09e-3)" "unprognostic (2.00e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (4.80e-2)" "unprognostic (2.30e-2)" "unprognostic (2.47e-3)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (5.43e-4)" "unprognostic (5.01e-2)" "unprognostic (3.05e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" 11.1 9.0 18.9 10.8 20.3 22.7 7.9 24.8 24.6 8.9 14.7 9.4 8.2 9.7 7.9 6.7 7.9 7.0 13.7 17.7 19.9 11.2 23.7 9.0 16.5 20.1 19.2 11.1 8.8 9.9 9.9 12.5 20.1 8.4 8.9 16.0 8.6 6.5 21.9 9.2 8.8 7.6 15.1 16.2 12.1 7.6 21.6 17.6 12.4 8.8 15.0 8.5 6.8 27.6 18.4 16.8 27.4 20.8 11.9 12.4 53.0 10.1 12.3 15.9 16.0 32.3 28.6 26.2 21.5 7.7 27.8 10.4 39.6 13.2 13.1 15.3 27.1 30.9 26.7 53.6 21.0 40.7 30.0 11.1 17.2 7.9 13.2 19.5 18.1 43.3 45.0 15.1 10.6 29.7 41.2 69.4 45.5 24.9 11.8 30.1 11.4 38.2 23.0 15.3 32.3 26.5 21.8 7.4 21.6 37.8 10.3 59.4 9.3 13.8 30.6 12.9 17.8 22.3 29.8 54.1 22.6 31.5 20.9 32.8 28.6 54.8 9.5 29.0 16.0 54.2 14.4 13.7 24.1 44.8 26.8 17.4 10.4 16.9 45.6 30.0 12.7 16.6 18.9 20.3 24.8 24.6 17.7 19.9 20.1 19.2 20.1 15.1 21.6 27.6 30.8 16.0 25.3 16.0 55.0 15.9 38.1 25.7 5.7 22.0 16.6 16.4 23.8 21.5 23.1 11.0 8.4 35.5 24.3 17.1 29.4 27.9 31.4 12.5 10.1 24.6 5.4 42.5 20.6 25.1 31.3 16.9 18.3 8.5 46.3 17.7 20.7 12.3 29.9 18.5 17.6 16.3 69.2 22.2 93.7 45.6 9.9 32.8 44.4 44.0 29.7 17.4 16.5 20.6 25.9 23.8 114.4 7.5 16.6 48.1 8.9 23.4 23.3 20.3 13.1 9.6 16.0 24.8 19.1 9.3 12.6 10.5 23.0 15.6 18.6 19.6 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MFSD11 "FLJ20226, FLJ22196" ENSG00000092931 "Major facilitator superfamily domain containing 11" O43934 17 76735865-76781449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 246.0;Early spermatids: 193.4;Late spermatids: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022001 Uncertain NA No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" "HPA022001: AB_2297599" "unprognostic (2.84e-2)" "unprognostic (1.22e-1)" "unprognostic (2.43e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-3)" "unprognostic (1.68e-2)" "unprognostic (2.06e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (3.41e-1)" "unprognostic (1.18e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.90e-4)" 14.5 13.8 8.9 13.2 9.9 16.5 15.5 12.0 10.2 14.3 5.9 19.7 16.3 12.6 16.4 17.8 11.9 13.1 19.1 9.7 8.7 11.9 16.9 16.1 12.8 10.0 9.0 9.7 15.1 22.2 15.5 19.9 11.6 11.5 20.5 38.1 15.4 12.2 27.8 18.3 16.8 15.3 7.2 14.2 20.2 23.0 9.9 14.0 15.7 21.1 14.7 12.1 16.4 11.7 25.0 13.8 16.0 15.1 33.7 20.3 18.8 21.6 20.0 20.4 18.1 28.1 44.5 20.1 17.9 22.2 22.4 23.5 11.5 11.3 21.2 9.3 22.8 19.3 27.1 19.6 16.1 10.6 19.1 24.4 18.0 26.3 11.8 29.5 39.6 26.3 24.5 29.0 26.4 18.6 24.7 17.7 6.7 28.3 8.0 19.2 20.7 41.9 15.9 18.3 15.4 26.1 20.7 29.0 19.3 23.4 51.0 16.3 27.9 36.9 17.8 23.5 18.1 32.1 13.7 29.9 28.6 9.3 25.0 14.5 15.2 13.4 15.9 17.7 6.6 7.6 14.2 16.1 16.7 9.1 8.6 10.6 18.7 7.9 14.7 11.8 21.1 9.4 8.9 9.9 12.0 10.2 9.7 8.7 10.0 9.0 11.6 7.2 9.9 11.7 15.9 12.8 14.0 45.4 21.3 16.8 16.3 21.1 48.9 39.3 20.5 14.7 18.1 12.8 22.7 14.7 246.0 38.6 19.5 34.3 5.9 15.3 193.4 12.5 14.9 19.5 16.8 30.9 51.9 18.0 78.0 18.9 25.5 14.1 27.3 12.0 17.9 19.4 33.7 40.4 68.2 14.6 20.3 23.9 19.0 213.9 18.3 24.9 19.6 40.3 22.8 24.6 20.6 48.7 63.1 20.9 14.0 13.9 47.3 16.3 23.2 9.9 13.5 103.3 6.6 15.6 15.7 37.8 18.0 33.9 17.2 41.3 27.0 11.5 18.3 15.8 MFSD12 "C19orf28, MGC20700, PP3501" ENSG00000161091 "Major facilitator superfamily domain containing 12" Q6NUT3 19 3538261-3574290 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Melanin biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.7;Extravillous trophoblasts: 142.4;Melanocytes: 195.7;Syncytiotrophoblasts: 92.6" "Cancer enriched" "Detected in all" 7 "melanoma: 124.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 261.4;SK-MEL-30: 339.8;WM-115: 628.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042149, HPA043088" Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "HPA042149: AB_2677875, HPA043088: AB_2678308" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "prognostic favorable (5.66e-6)" "unprognostic (1.56e-2)" "unprognostic (6.51e-2)" "prognostic unfavorable (6.61e-4)" "prognostic unfavorable (2.34e-4)" "unprognostic (3.19e-2)" "unprognostic (9.12e-3)" "unprognostic (1.56e-2)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.70e-4)" "unprognostic (1.95e-1)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" 23.3 26.4 25.8 24.1 26.4 30.5 19.3 21.8 33.0 18.9 9.3 17.7 15.0 18.0 12.9 22.7 21.8 9.5 17.6 41.2 18.1 55.0 35.8 29.2 20.3 29.0 23.8 14.7 38.5 13.9 25.9 17.6 28.9 21.4 6.1 10.8 29.7 11.2 16.4 53.7 27.2 11.6 19.2 37.9 22.8 13.6 29.9 24.7 19.0 4.0 10.8 19.5 17.0 58.0 97.6 76.4 18.6 48.9 37.9 29.2 66.9 58.3 31.2 66.6 72.7 33.1 32.4 27.3 43.2 31.2 106.4 60.1 24.3 30.2 23.8 60.0 69.0 15.9 261.4 34.9 47.4 34.9 51.1 26.2 44.9 68.6 15.9 25.5 18.1 40.2 77.1 38.2 17.3 58.0 35.0 61.8 34.9 42.9 62.1 24.3 26.2 115.1 27.9 41.0 70.0 35.5 115.0 53.4 339.8 23.1 18.2 71.6 75.8 30.1 44.4 123.8 67.1 43.8 26.9 25.1 132.4 88.2 628.4 0.1 3.7 2.6 1.8 7.7 1.8 2.3 2.8 1.4 2.7 1.4 2.4 1.9 1.2 0.5 7.7 12.1 0.5 1.7 25.8 26.4 21.8 33.0 41.2 18.1 29.0 23.8 28.9 19.2 29.9 58.0 15.4 6.4 2.8 5.5 12.9 26.5 6.8 4.9 1.8 15.6 19.9 14.0 1.9 8.6 6.1 20.2 6.2 16.8 21.5 11.6 0.0 23.1 120.7 26.9 20.9 13.1 28.1 3.8 10.2 31.4 142.4 10.9 14.8 42.5 0.0 57.3 6.4 22.3 76.9 37.0 8.0 18.4 2.0 24.8 54.4 30.4 2.5 47.7 195.7 13.1 20.7 9.3 5.2 7.5 25.5 34.2 16.2 3.4 12.6 16.7 18.7 34.0 8.1 12.7 13.1 5.4 12.0 4.0 9.0 8.4 25.4 92.6 10.9 11.1 13.2 13.8 MFSD13A "bA18I14.8, C10orf77, FLJ22529, TMEM180" ENSG00000138111 "Major facilitator superfamily domain containing 13A" Q14CX5 10 102461395-102477045 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Alveolar cells type 2: 15.4;Hofbauer cells: 15.7;Horizontal cells: 21.9;Syncytiotrophoblasts: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018031 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Cytosol" "HPA018031: AB_2204891" "unprognostic (2.24e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.73e-2)" "unprognostic (1.13e-1)" "unprognostic (2.79e-1)" "unprognostic (2.11e-1)" "unprognostic (9.16e-3)" "unprognostic (4.70e-2)" "unprognostic (4.03e-2)" "unprognostic (8.10e-2)" "unprognostic (2.04e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.66e-3)" "unprognostic (2.44e-1)" "unprognostic (2.74e-1)" "unprognostic (4.02e-2)" 2.3 2.5 10.0 3.2 13.0 5.2 2.1 14.1 12.8 2.4 2.3 5.0 5.5 3.1 0.7 3.0 2.3 2.3 3.2 10.8 7.2 2.5 6.3 9.0 3.2 7.7 7.7 1.4 3.8 1.7 4.1 2.3 7.8 3.1 3.2 4.9 1.8 0.9 2.3 11.7 4.4 2.5 6.5 6.9 4.0 3.7 9.2 1.8 5.4 1.4 3.6 2.2 2.6 9.4 12.0 5.4 4.0 9.6 0.4 0.4 6.2 2.3 6.0 4.6 10.5 10.7 16.0 10.6 11.8 0.9 4.4 14.6 7.4 6.3 1.7 13.5 6.8 13.1 8.2 5.6 10.1 6.7 12.3 5.2 2.6 2.6 4.6 3.7 5.3 14.2 3.0 5.7 0.4 2.4 11.3 4.3 6.8 10.5 5.2 13.6 0.6 1.8 2.0 3.1 10.0 9.5 2.2 1.2 5.2 1.4 6.0 4.0 1.6 2.1 2.5 2.6 3.3 1.9 5.5 14.0 11.6 10.9 2.9 0.4 4.3 3.5 2.9 3.2 2.8 3.4 2.7 2.3 4.5 1.4 2.8 3.2 2.5 1.2 1.8 0.4 0.8 2.6 10.0 13.0 14.1 12.8 10.8 7.2 7.7 7.7 7.8 6.5 9.2 9.4 4.1 19.2 15.4 0.0 1.1 0.0 1.5 0.0 0.6 8.2 1.5 1.9 0.0 1.5 0.6 1.8 4.2 1.8 5.7 2.6 0.0 2.8 1.8 1.0 1.0 3.8 2.4 3.6 0.0 3.6 2.6 1.6 5.6 1.6 1.3 2.8 6.4 4.0 15.7 21.9 0.0 3.8 0.0 4.8 0.0 1.0 0.9 8.7 0.0 0.0 5.6 3.2 2.1 0.0 0.0 3.2 4.6 2.2 0.8 1.4 5.6 1.5 0.7 13.8 0.0 2.8 1.1 4.5 3.0 2.4 0.0 28.5 3.2 4.0 4.5 1.4 MFSD14B "FLJ14753, HIATL1" ENSG00000148110 "Major facilitator superfamily domain containing 14B" Q5SR56 9 94374569-94461042 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 66.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017978 Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "HPA017978: AB_2116836" "unprognostic (3.03e-2)" "unprognostic (2.28e-1)" "unprognostic (3.96e-3)" "unprognostic (5.95e-3)" "unprognostic (1.39e-1)" "unprognostic (3.29e-2)" "unprognostic (4.13e-3)" "unprognostic (3.27e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-2)" "unprognostic (1.16e-2)" "unprognostic (3.11e-3)" "unprognostic (1.15e-1)" "unprognostic (9.12e-2)" "unprognostic (6.63e-2)" "unprognostic (1.93e-1)" "unprognostic (9.01e-2)" 24.4 32.3 25.5 26.1 28.0 18.4 24.6 26.6 33.1 24.0 34.6 24.4 18.8 24.1 29.0 40.2 26.7 20.7 20.8 24.0 26.3 21.9 15.2 32.0 29.4 29.1 28.5 19.0 18.1 95.1 12.7 33.3 28.5 21.3 28.5 17.9 20.8 21.3 12.4 42.4 21.3 23.8 28.5 25.2 24.9 14.1 27.3 30.7 25.7 14.1 34.6 34.7 27.6 29.8 76.4 48.3 36.9 28.8 79.3 56.4 58.4 72.5 62.7 63.3 61.6 24.4 88.9 91.2 42.2 63.1 73.0 163.9 44.6 46.3 61.0 65.7 23.9 31.6 43.0 36.8 56.2 100.0 55.8 52.2 68.5 67.1 51.2 35.4 54.9 49.3 60.6 52.5 85.2 57.8 73.7 56.6 54.2 111.0 38.4 36.6 84.6 29.6 68.2 57.8 35.4 46.4 61.6 71.6 79.6 44.0 32.9 58.3 59.4 65.6 46.1 102.1 68.2 57.6 77.2 24.8 58.6 48.1 60.1 0.5 6.1 4.9 4.1 9.2 3.7 3.3 3.6 4.2 6.2 2.1 3.6 5.1 8.0 3.1 6.3 6.0 4.0 3.0 25.5 28.0 26.6 33.1 24.0 26.3 29.1 28.5 28.5 28.5 27.3 29.8 21.6 6.4 20.0 0.0 17.3 0.0 23.2 0.0 22.2 12.2 29.4 15.6 0.0 14.3 6.8 44.1 4.2 14.2 20.6 16.2 7.9 16.8 3.6 32.2 20.7 18.9 7.3 30.7 0.0 19.0 26.4 17.3 16.3 32.7 3.8 14.1 26.4 13.5 28.9 5.0 0.0 22.9 0.0 66.1 0.0 3.1 16.8 31.0 0.0 0.0 39.1 19.5 15.5 0.0 0.0 26.7 12.1 16.1 12.7 38.5 11.7 7.6 7.3 9.9 13.1 18.1 14.9 14.1 18.2 37.6 0.0 19.2 15.7 17.7 14.4 42.6 MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 110.6;Respiratory ciliated cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" 20.8 40.3 29.1 12.7 31.7 7.6 21.3 37.0 40.3 21.8 0.0 31.8 19.8 10.5 32.8 40.6 19.5 15.8 17.9 35.5 27.6 10.8 2.3 26.4 14.8 45.8 48.3 4.1 16.8 64.5 35.4 8.6 52.4 23.0 28.9 14.9 30.8 32.3 6.4 29.8 24.6 14.4 28.6 20.9 32.1 7.9 38.3 19.9 38.9 14.2 20.6 22.9 21.5 51.2 25.1 15.2 0.5 5.2 10.6 13.6 20.4 12.7 25.3 8.4 10.5 5.6 31.1 39.1 5.8 26.4 15.6 41.5 7.4 22.1 9.5 79.7 11.6 20.9 14.2 2.9 4.2 8.3 6.4 2.1 39.3 12.5 8.1 27.1 3.0 30.5 5.4 42.2 2.2 9.7 38.8 1.8 3.4 27.1 16.1 8.6 1.2 34.1 15.9 45.1 47.5 12.2 17.9 41.7 24.9 1.7 13.6 9.5 12.6 1.4 2.9 16.6 19.7 19.3 8.6 13.8 13.5 16.9 6.9 4.6 1.1 0.4 1.4 0.3 1.5 1.6 1.8 2.0 1.5 0.7 0.9 1.9 0.1 2.1 0.5 0.7 3.5 0.8 29.1 31.7 37.0 40.3 35.5 27.6 45.8 48.3 52.4 28.6 38.3 51.2 48.6 32.1 20.0 7.2 7.6 6.4 11.5 11.7 10.8 9.7 16.8 9.8 21.4 5.7 30.3 23.9 8.4 0.2 14.9 25.1 0.0 13.2 46.8 27.9 5.9 26.7 35.4 7.8 55.7 20.5 0.2 8.9 31.1 22.5 24.0 8.7 16.1 0.8 4.0 28.6 47.9 42.7 12.2 4.0 8.0 13.7 5.6 12.3 8.8 11.2 9.7 6.8 3.1 41.7 110.6 24.9 20.8 5.3 14.9 13.5 13.6 1.0 88.5 7.9 0.0 16.7 7.2 1.0 1.4 28.8 18.3 0.0 17.0 18.6 21.1 22.7 MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Vesicles Nucleoplasm "HPA044802: AB_10963221" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (8.10e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-3)" "unprognostic (3.14e-1)" "prognostic favorable (2.21e-4)" 4.6 5.7 1.3 6.8 1.3 2.6 6.9 1.9 1.6 6.2 1.1 6.8 10.0 5.6 3.9 5.4 5.5 4.8 3.8 1.1 1.7 6.4 10.0 4.8 5.4 1.4 1.3 6.8 8.1 9.1 7.1 5.9 1.5 5.5 8.2 4.6 5.8 4.4 3.7 5.9 7.6 5.8 1.1 7.3 6.4 3.9 0.8 5.2 7.0 4.4 7.9 5.3 5.9 2.2 10.9 7.3 9.5 4.6 7.2 6.9 7.0 8.3 10.3 10.2 10.5 5.2 14.3 5.2 14.5 14.3 14.8 7.8 10.2 7.4 14.4 10.8 7.9 5.7 9.1 8.0 9.4 6.0 6.6 8.3 2.7 8.6 7.7 5.0 10.6 6.6 9.5 5.9 14.6 8.9 5.0 1.9 1.7 11.8 5.2 5.3 0.6 4.7 7.5 13.9 8.5 2.9 9.0 12.0 3.5 6.4 5.6 5.1 6.7 2.9 3.1 10.7 7.8 12.5 22.1 9.6 10.3 5.3 8.8 1.9 1.6 2.8 2.5 2.4 2.4 2.5 2.7 2.2 1.6 1.1 2.4 2.6 2.5 2.4 3.7 2.2 3.4 1.2 1.3 1.3 1.9 1.6 1.1 1.7 1.4 1.3 1.5 1.1 0.8 2.2 9.5 12.8 14.1 17.0 18.8 3.2 4.9 8.5 10.2 17.2 8.1 5.3 3.0 5.7 14.0 16.5 20.9 12.5 17.9 7.2 1.9 8.5 10.4 7.7 7.2 7.2 4.2 3.8 32.1 7.0 7.3 8.6 11.7 8.2 12.7 18.4 8.9 10.1 7.6 11.8 34.9 6.8 10.2 8.5 3.3 14.7 9.3 6.5 3.6 27.2 10.5 8.6 20.6 20.6 24.6 7.8 9.5 9.4 19.9 5.4 11.1 6.3 12.1 24.9 6.6 5.8 6.6 12.6 8.4 8.9 5.7 22.0 13.7 11.4 7.3 4.8 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 441.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 276.3;OE19: 558.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 61.8 92.7 43.5 30.4 42.9 42.6 66.6 45.1 60.6 63.6 54.8 112.5 132.5 39.2 82.1 177.6 70.8 87.6 118.3 42.6 45.7 99.2 393.2 49.0 36.0 46.6 44.6 26.3 66.2 102.0 44.6 75.6 46.5 74.9 121.2 7.8 90.6 50.0 104.2 97.1 143.5 57.4 46.6 60.5 72.5 50.6 45.3 35.1 45.8 118.4 64.6 86.7 78.4 48.9 40.8 58.5 28.7 0.3 4.8 15.4 17.7 7.2 66.1 3.2 10.7 62.3 276.3 0.1 158.2 17.5 13.6 74.8 52.7 81.2 4.9 22.3 47.7 174.9 57.3 251.5 13.3 152.7 130.0 53.0 197.2 2.1 12.5 63.9 166.3 0.3 75.9 25.7 23.3 33.9 0.2 24.7 6.5 558.9 59.4 12.7 33.4 54.0 153.0 87.4 71.9 21.6 53.2 83.2 64.8 2.0 52.9 202.2 104.9 5.6 27.3 7.8 6.4 29.7 22.5 9.7 3.8 254.8 12.6 43.8 103.8 30.4 4.1 64.8 2.9 1.3 7.6 3.5 147.0 2.4 2.3 2.6 17.7 26.4 22.2 194.6 37.7 39.4 43.5 42.9 45.1 60.6 42.6 45.7 46.6 44.6 46.5 46.6 45.3 48.9 327.9 25.6 36.6 5.5 7.7 61.1 295.9 316.7 75.7 7.8 99.1 57.3 100.5 205.9 185.5 95.6 25.0 85.3 71.0 168.3 90.1 121.0 6.3 132.5 27.1 238.4 121.8 60.2 19.4 138.6 62.8 31.8 90.2 172.9 43.2 56.9 203.1 419.3 378.1 6.7 24.2 215.1 170.9 107.8 77.8 12.8 44.4 85.3 39.2 49.6 83.6 14.1 27.8 11.6 4.7 121.8 213.1 33.4 7.1 94.6 441.1 277.2 126.6 3.5 13.1 44.6 49.6 4.6 15.1 264.0 124.9 67.2 15.2 43.6 258.2 344.9 MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA055922: AB_2682971, HPA056816: AB_2683243" "unprognostic (1.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (5.65e-2)" "unprognostic (6.73e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.83e-1)" "unprognostic (8.62e-3)" "unprognostic (3.26e-1)" 25.6 22.0 11.0 23.4 13.1 33.2 21.4 12.9 14.9 23.9 13.2 24.3 23.9 23.7 29.2 13.7 16.0 20.6 20.6 10.9 13.6 21.1 74.5 21.5 26.9 10.8 12.3 25.4 38.7 30.1 15.2 23.1 11.7 39.3 29.5 24.4 33.2 22.1 23.7 17.4 25.9 23.8 10.7 27.3 45.0 36.5 11.5 25.7 31.7 20.5 26.2 21.0 14.1 12.8 24.8 18.8 26.5 42.5 92.8 47.1 46.5 34.8 49.4 36.2 43.1 16.6 26.2 24.0 33.0 41.8 20.5 39.9 28.5 31.3 37.8 38.1 21.6 27.7 21.5 31.5 88.6 50.7 34.7 45.2 35.0 35.9 60.8 44.8 41.4 28.9 34.8 44.4 30.7 15.9 34.3 33.8 33.2 76.8 27.5 24.4 70.8 47.8 23.1 22.8 30.4 31.3 38.6 36.2 30.4 36.2 38.2 37.5 31.7 27.5 17.9 44.5 41.3 48.4 30.9 23.8 36.7 25.4 37.5 26.8 15.6 36.5 17.6 22.4 17.7 20.7 14.7 17.5 11.7 18.6 16.4 17.8 27.1 22.5 26.0 13.2 19.2 13.5 11.0 13.1 12.9 14.9 10.9 13.6 10.8 12.3 11.7 10.7 11.5 12.8 48.5 70.5 49.6 31.3 46.9 18.7 26.8 20.4 29.0 60.9 24.3 35.3 65.0 25.8 47.1 5.5 31.3 28.6 73.8 35.2 0.0 25.1 37.0 34.9 72.5 36.4 60.4 26.3 51.4 34.8 17.0 53.0 79.5 42.0 17.7 44.2 25.4 63.3 20.4 45.4 58.0 95.3 32.6 22.0 14.0 24.9 37.0 32.9 19.6 35.6 32.1 31.8 44.3 41.2 29.1 26.4 25.8 48.9 54.4 39.0 41.3 19.4 44.7 41.5 19.7 57.9 46.6 55.7 42.1 21.9 16.1 35.8 47.8 70.2 24.6 29.4 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-138 MG: 109.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.7 3.8 13.9 12.2 13.6 11.6 2.5 61.6 38.1 6.9 42.6 18.8 9.8 12.3 7.2 18.6 7.4 10.0 42.2 37.8 0.0 2.3 2.9 17.5 3.3 0.0 0.0 3.9 4.1 1.0 0.2 7.3 0.0 2.9 16.3 4.0 0.8 9.6 16.8 14.0 10.8 30.8 0.0 3.3 6.7 32.5 0.0 1.9 6.1 4.1 2.5 12.4 0.3 19.9 29.1 9.7 0.4 2.7 2.3 6.8 14.2 32.1 53.7 16.2 28.3 24.3 23.3 0.2 8.4 25.3 47.7 25.0 4.0 65.1 41.6 35.9 4.8 27.5 4.1 0.9 12.8 5.3 2.7 12.7 11.1 76.0 54.6 25.3 46.9 1.6 43.5 0.8 22.9 1.2 0.3 1.6 1.2 13.6 9.8 0.3 15.2 14.2 2.1 35.5 14.3 0.8 8.6 38.6 2.9 9.9 4.5 2.3 42.6 109.6 35.0 17.4 39.6 0.9 2.6 1.5 64.3 5.2 1.4 0.1 4.2 0.5 1.3 0.7 1.5 0.1 0.8 0.4 3.4 0.2 0.0 0.4 8.9 2.2 0.4 0.9 0.7 1.5 13.9 13.6 61.6 38.1 37.8 0.0 0.0 0.0 0.0 0.0 0.0 19.9 3.2 41.7 37.1 7.2 1.2 10.1 11.8 4.5 4.0 5.7 4.2 5.3 32.2 7.2 8.5 3.7 0.0 2.6 11.2 66.5 0.0 10.2 74.4 7.8 8.9 9.2 22.6 35.6 193.5 14.3 12.6 9.0 12.2 11.4 1.3 1.4 12.8 19.6 3.4 0.0 108.8 10.6 6.1 10.1 5.6 192.7 21.1 11.1 5.4 4.7 21.6 0.5 8.2 6.6 17.5 42.5 24.0 112.8 2.1 8.9 18.3 0.9 5.5 1.6 13.1 1.9 29.4 1.2 1.3 1.7 9.5 2.3 10.8 0.7 14.5 11.9 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 MOG "BTN6, BTNL11" ENSG00000204655 "Myelin oligodendrocyte glycoprotein" Q16653 6 29657002-29672372 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 73.8" "Cell type enriched" "Detected in some" 49 "Oligodendrocytes: 472.3" "Cancer enriched" "Detected in single" 45 "glioma: 15.1" "Region enriched" "Detected in all" 4 "cerebral cortex: 73.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "white matter: 1396.5" "Low region specificity" "Detected in all" HPA021873 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA021873: AB_1854055" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (3.00e-4)" "unprognostic (4.89e-2)" "unprognostic (4.90e-2)" 0.0 0.0 4.9 0.0 11.0 0.0 0.0 8.6 73.8 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 6.8 8.4 0.1 0.0 0.0 0.0 9.9 8.4 0.1 0.0 0.0 0.3 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 11.0 8.6 73.8 6.8 8.4 9.9 8.4 10.1 8.1 8.4 17.8 0.0 0.0 1.1 0.7 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.0 9.5 472.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.3 MOSPD1 dJ473B4 ENSG00000101928 "Motile sperm domain containing 1" Q9UJG1 X 134887632-134915257 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 106.9;Endometrial ciliated cells: 80.3;Erythroid cells: 150.1;Late spermatids: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031158 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Vesicles" "HPA031158: AB_10603874" "unprognostic (2.23e-3)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.77e-1)" "unprognostic (3.36e-1)" "unprognostic (6.78e-3)" "unprognostic (5.15e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (6.20e-3)" "unprognostic (4.27e-2)" "unprognostic (6.45e-3)" "unprognostic (2.92e-2)" "unprognostic (2.01e-1)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" 5.1 14.0 4.1 4.9 4.1 15.4 8.3 4.5 5.5 8.7 12.4 6.7 5.9 16.2 12.8 15.2 26.9 7.1 20.0 4.0 4.4 10.9 7.6 7.5 6.2 4.8 4.4 10.9 7.7 15.1 3.4 11.8 4.5 8.4 7.4 6.7 9.4 7.7 21.5 10.4 5.6 11.3 4.4 6.4 5.4 10.4 4.4 9.7 9.6 14.1 8.5 10.6 8.8 4.5 19.6 15.1 12.5 8.7 19.5 11.4 27.3 32.2 58.2 30.4 29.4 37.2 7.6 6.5 43.7 20.6 54.9 6.9 19.6 16.7 39.9 21.9 11.5 5.6 36.7 15.1 82.2 15.6 9.1 20.6 20.0 34.2 14.7 34.5 22.6 13.3 7.0 25.9 37.3 27.2 11.2 7.1 12.8 10.2 34.1 8.3 22.2 12.4 13.0 55.3 7.4 9.2 16.3 16.2 56.7 60.6 6.5 9.7 11.3 14.9 9.2 56.0 29.0 20.1 29.0 10.4 20.2 26.4 19.9 4.9 5.4 10.5 5.8 4.3 7.9 4.7 6.9 6.4 6.3 4.1 7.7 7.6 3.5 5.1 5.1 6.7 12.4 4.1 4.1 4.1 4.5 5.5 4.0 4.4 4.8 4.4 4.5 4.4 4.4 4.5 13.2 6.4 5.8 3.9 11.0 21.3 10.6 13.8 29.6 8.5 10.8 9.4 43.7 4.3 11.8 11.0 2.1 9.0 6.9 7.6 21.5 26.3 106.9 80.3 10.5 12.2 4.2 150.1 7.6 12.4 16.0 10.5 8.6 12.0 5.7 21.5 13.9 6.7 14.9 5.0 8.8 6.9 16.2 11.9 7.7 82.9 6.8 7.5 30.2 4.7 7.4 9.3 11.3 9.0 4.4 20.9 12.7 10.9 14.7 11.8 5.7 27.9 20.0 8.5 6.6 6.8 16.9 3.8 6.6 12.2 20.5 26.1 13.2 15.8 7.1 9.9 MOSPD3 "CDS3, NET30" ENSG00000106330 "Motile sperm domain containing 3" O75425 7 100612102-100615384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1472.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041137, HPA048240" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 32: U-937 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA041137: AB_10803996, HPA048240: AB_2680325" "unprognostic (1.24e-1)" "unprognostic (8.98e-2)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" "unprognostic (1.25e-2)" "unprognostic (1.80e-2)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (9.88e-2)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (8.65e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" 16.7 36.6 14.9 5.6 14.1 13.8 16.8 12.6 19.0 22.1 11.2 17.2 6.8 18.7 3.1 33.5 16.2 8.3 15.1 13.4 14.0 21.0 38.9 13.6 8.0 15.5 13.6 19.2 18.4 7.8 15.6 4.1 13.7 18.1 3.0 2.1 19.6 7.0 10.7 41.8 12.8 5.1 13.3 16.3 19.6 57.9 14.4 7.1 14.9 5.4 5.3 17.4 23.4 13.3 12.6 16.2 13.0 22.9 6.6 4.9 9.3 9.3 10.7 9.3 9.3 15.4 16.1 7.7 20.2 8.3 13.3 9.5 7.5 12.9 1.7 20.4 9.9 8.0 12.1 23.2 8.5 6.1 30.0 13.8 10.8 7.9 4.6 8.2 15.8 12.7 19.2 15.4 9.4 35.9 17.4 47.4 11.9 16.0 24.9 16.4 13.6 18.9 14.8 17.9 7.1 42.8 17.5 26.3 9.8 5.3 16.2 18.3 19.0 18.5 28.3 38.2 9.2 12.2 12.4 5.5 18.3 69.5 22.7 38.7 29.1 40.3 31.3 22.7 36.9 21.7 36.0 36.7 31.7 22.4 21.3 22.2 21.3 37.5 15.9 21.1 57.2 14.8 14.9 14.1 12.6 19.0 13.4 14.0 15.5 13.6 13.7 13.3 14.4 13.3 18.5 9.6 7.0 4.6 10.9 12.1 20.0 31.0 21.1 5.7 28.0 25.8 3.6 21.5 16.9 20.2 6.2 6.6 19.8 9.3 43.0 43.2 324.0 15.7 12.8 16.4 21.6 21.7 4.7 42.8 26.3 16.4 12.8 11.2 3.8 11.5 23.6 31.3 29.8 6.7 7.6 14.2 22.4 25.1 14.8 1472.9 27.7 15.6 26.6 1.9 17.4 19.0 25.7 8.5 4.9 43.9 17.3 21.8 7.8 16.2 15.1 48.7 15.9 4.0 13.1 10.7 17.5 20.3 31.1 26.7 19.6 6.2 24.4 16.7 17.0 25.3 MPC1L SLC54A3 ENSG00000238205 "Mitochondrial pyruvate carrier 1 like" P0DKB6 X 40623566-40624136 "Metabolic proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 18.4" "Cell type enriched" "Detected in single" 5 "Endometrial ciliated cells: 1.2" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (8.47e-4)" "unprognostic (1.00e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPDU1 "CDGIf, Lec35, PQLC5, SL15, SLC66A5" ENSG00000129255 "Mannose-P-dolichol utilization defect 1" O75352 17 7583529-7592789 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 157.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014845 Uncertain Supported "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Mitochondria "HPA014845: AB_1854072" "unprognostic (1.96e-1)" "unprognostic (8.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.36e-2)" "unprognostic (5.00e-2)" "unprognostic (5.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (4.70e-2)" "unprognostic (3.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.34e-3)" "unprognostic (9.00e-2)" "unprognostic (2.60e-1)" "unprognostic (2.48e-3)" "unprognostic (2.93e-1)" 31.9 41.1 33.0 32.8 34.1 63.3 39.2 35.5 34.5 33.3 41.9 65.5 53.3 17.4 33.5 37.7 32.0 35.7 20.4 31.7 34.2 72.2 107.0 33.3 30.7 34.3 33.9 10.9 39.7 57.4 15.6 37.1 33.7 33.7 69.6 25.4 33.6 18.4 21.3 29.0 48.5 28.7 34.2 28.4 54.5 14.5 36.2 25.9 35.7 21.3 38.0 43.2 21.9 34.9 51.0 111.8 75.9 54.1 83.8 74.4 50.5 81.1 104.6 142.4 98.6 58.0 85.0 28.8 54.8 128.1 65.0 98.4 102.2 134.3 116.6 63.8 118.8 55.7 65.8 98.7 101.0 49.3 89.8 77.9 105.2 133.4 76.4 64.7 105.8 84.9 87.1 38.6 151.6 70.1 35.9 48.4 85.2 107.4 55.8 81.6 56.4 60.7 145.1 52.1 45.8 90.1 104.4 75.9 34.4 59.5 83.8 50.1 76.5 67.5 36.9 36.8 111.2 20.3 34.6 27.0 97.1 62.3 103.5 16.8 44.2 14.0 16.9 73.1 12.8 18.1 16.1 22.1 52.4 16.5 15.4 18.3 6.5 17.4 69.1 48.5 26.4 24.9 33.0 34.1 35.5 34.5 31.7 34.2 34.3 33.9 33.7 34.2 36.2 34.9 30.1 9.6 23.0 5.5 30.4 10.7 34.9 51.0 22.2 18.1 34.7 22.7 5.1 34.3 31.0 23.9 12.5 111.5 26.5 106.8 35.2 62.7 3.2 22.2 23.3 28.2 37.2 96.8 4.5 76.1 93.8 27.5 53.5 28.1 14.5 28.6 25.0 49.7 79.7 16.8 5.6 68.9 40.7 30.5 23.6 5.7 17.1 46.1 24.9 4.7 35.9 28.5 21.6 6.6 9.3 69.7 76.8 6.4 38.5 37.1 78.0 48.0 20.3 23.3 26.3 30.6 24.7 22.9 26.4 20.7 12.6 157.6 26.0 37.1 77.1 40.9 MPPE1 "Cdc1, PGAP5" ENSG00000154889 "Metallophosphoesterase 1" Q53F39 18 11882622-11908366 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, GPI-anchor biosynthesis, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 100.8;neutrophil: 293.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 293.9" "Cell line enhanced" "Detected in all" "OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012639 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA012639: AB_1854088" "unprognostic (9.23e-2)" "unprognostic (1.54e-1)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.00e-2)" "unprognostic (4.46e-1)" "unprognostic (1.61e-1)" "prognostic favorable (6.45e-7)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" "unprognostic (6.15e-2)" 14.9 13.1 11.3 20.0 11.7 28.3 15.4 11.0 11.9 16.1 11.7 21.5 17.7 17.0 20.6 17.2 16.4 21.8 18.6 10.9 11.9 28.8 23.8 25.6 16.0 12.6 11.8 12.7 31.8 20.1 15.0 14.1 12.5 16.3 21.4 15.9 15.0 19.0 23.5 29.0 20.3 15.8 10.6 15.9 22.8 8.5 12.1 16.0 47.1 11.7 14.7 14.9 13.7 13.1 7.8 11.1 8.4 19.9 22.9 26.7 7.9 18.6 26.0 10.6 16.5 20.8 21.6 15.8 39.2 17.6 10.7 8.6 5.8 10.1 9.9 17.7 10.4 4.6 22.9 4.9 31.9 20.3 30.9 40.1 13.3 9.4 6.6 15.7 6.5 13.9 5.8 14.5 17.8 18.1 15.1 13.6 5.6 65.9 3.1 6.0 5.4 18.8 17.2 11.9 11.8 6.7 17.1 13.5 16.0 9.3 9.8 25.9 13.5 21.4 8.3 20.5 10.3 22.6 21.5 19.7 15.8 10.4 21.5 20.6 42.9 100.8 24.8 34.5 18.1 17.9 15.2 23.9 37.3 21.7 18.5 23.8 293.9 29.2 24.6 29.6 27.0 31.8 11.3 11.7 11.0 11.9 10.9 11.9 12.6 11.8 12.5 10.6 12.1 13.1 19.3 57.7 33.0 13.4 24.5 18.0 16.2 20.7 12.5 17.4 14.6 11.6 2.4 24.3 23.1 22.0 12.5 27.9 35.7 43.9 21.5 30.5 20.5 17.9 14.8 15.5 9.6 13.3 20.9 41.9 32.5 16.6 29.6 22.6 27.8 23.5 15.7 27.6 25.4 8.4 21.4 23.4 14.2 33.2 25.7 36.0 12.8 24.8 19.6 20.6 24.2 23.3 52.5 12.5 24.4 36.3 18.4 15.1 16.0 10.1 36.3 27.0 26.7 20.5 13.1 17.2 13.9 7.0 8.7 21.8 20.0 16.7 33.7 16.4 16.1 22.0 MPV17 SYM1 ENSG00000115204 "Mitochondrial inner membrane protein MPV17" P39210 2 27309492-27325680 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (9.34e-3)" "unprognostic (2.70e-1)" "unprognostic (9.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (6.99e-6)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (1.48e-1)" "unprognostic (1.44e-3)" "unprognostic (2.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.10e-3)" "unprognostic (4.62e-2)" 50.2 86.5 56.4 37.8 58.1 31.3 39.9 59.1 58.4 36.0 59.3 32.5 25.0 37.9 47.7 32.6 37.7 36.7 78.2 56.3 59.1 48.6 22.6 39.1 43.2 58.8 57.1 43.7 33.2 70.0 38.9 35.0 58.1 34.1 34.1 26.7 35.9 35.0 18.3 32.0 27.5 57.7 56.9 37.1 29.1 15.5 60.3 46.0 51.6 30.0 48.1 44.9 28.1 63.2 74.1 68.2 49.7 42.6 202.7 237.0 46.6 70.8 143.6 67.2 60.7 55.0 52.0 41.5 72.8 97.2 124.0 61.3 64.1 134.1 69.5 56.9 63.7 79.5 58.8 105.6 125.4 47.3 48.7 229.3 116.3 118.6 169.4 94.3 100.2 49.8 77.0 77.1 113.9 107.4 46.9 71.5 55.7 106.7 69.1 64.6 73.2 85.2 149.2 58.5 33.1 107.2 37.6 43.7 82.1 49.3 49.0 60.6 88.6 67.0 68.8 83.4 76.4 108.1 106.1 130.4 109.2 105.4 76.1 59.5 93.7 42.9 59.3 81.4 64.4 84.5 60.5 67.4 120.5 73.6 58.0 67.8 7.8 76.0 81.7 87.4 81.4 92.1 56.4 58.1 59.1 58.4 56.3 59.1 58.8 57.1 58.1 56.9 60.3 63.2 36.0 25.6 29.3 10.7 26.3 17.2 32.8 69.2 33.0 20.5 49.5 52.8 48.9 18.6 46.5 33.1 8.4 51.1 26.3 8.8 64.6 43.3 27.4 17.3 32.6 35.9 16.8 21.6 18.4 24.3 60.2 37.5 12.2 17.5 42.5 28.7 28.2 9.9 116.9 8.4 22.7 15.0 59.0 28.5 24.0 34.2 35.4 33.7 40.9 8.4 38.1 38.9 28.8 13.6 15.5 20.7 12.9 35.0 31.4 32.1 17.6 87.1 36.7 12.7 0.0 30.1 30.8 15.5 21.2 33.9 18.8 59.4 22.2 41.8 17.7 30.7 MPV17L2 "FKSG24, MGC12972" ENSG00000254858 "MPV17 mitochondrial inner membrane protein like 2" Q567V2 19 18193218-18196948 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043111 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043111: AB_10794176" "unprognostic (3.71e-1)" "unprognostic (2.75e-3)" "unprognostic (5.52e-2)" "unprognostic (1.28e-1)" "unprognostic (6.74e-2)" "unprognostic (8.23e-2)" "unprognostic (4.41e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (9.93e-3)" "unprognostic (5.21e-2)" "unprognostic (1.99e-1)" "prognostic favorable (2.30e-4)" "unprognostic (1.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (5.20e-2)" 9.2 22.3 10.5 6.4 11.1 3.9 9.7 10.6 12.5 7.3 10.5 15.6 5.3 8.9 8.9 9.2 9.1 4.6 19.3 10.4 11.0 14.5 22.1 9.3 7.1 11.2 11.3 8.8 12.6 10.1 11.8 4.8 11.3 10.7 5.0 4.3 9.5 9.9 15.4 9.3 9.7 7.4 11.0 10.4 13.8 6.8 11.2 5.6 10.0 16.5 7.1 10.8 6.9 11.9 13.7 15.3 15.7 23.1 11.1 7.0 31.3 17.7 16.6 31.9 28.7 17.3 12.5 17.3 34.3 10.9 23.3 15.9 29.4 22.1 15.3 12.7 36.2 13.5 11.0 22.9 17.8 17.4 19.7 10.0 18.2 18.4 21.5 5.9 14.4 26.2 28.4 17.1 16.3 48.2 26.3 19.6 19.3 31.2 59.3 22.6 13.8 24.0 20.8 9.2 17.8 13.2 15.6 21.7 14.3 10.9 9.4 16.0 13.3 18.3 9.5 56.8 20.5 13.3 26.6 26.0 12.6 29.0 19.6 13.4 19.4 18.2 16.1 27.1 19.3 25.8 12.7 12.6 25.3 16.2 10.2 12.9 5.5 18.3 19.0 24.2 18.0 11.9 10.5 11.1 10.6 12.5 10.4 11.0 11.2 11.3 11.3 11.0 11.2 11.9 9.5 6.4 3.9 2.9 14.1 10.6 5.8 10.3 15.4 8.1 14.2 11.8 8.2 7.2 7.8 11.0 2.1 22.0 9.4 5.8 23.5 17.9 1.4 3.2 7.4 11.5 6.6 2.5 1.2 26.0 29.4 7.0 5.1 6.1 1.3 6.4 5.7 7.8 18.5 6.7 1.1 9.5 12.2 6.3 24.5 0.2 3.4 13.0 12.4 3.7 32.3 7.8 8.2 3.0 3.3 22.5 6.2 5.3 14.9 10.1 6.2 8.2 2.1 9.8 0.0 3.0 9.7 9.1 8.4 5.4 11.1 22.8 6.6 12.8 9.8 3.9 MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017642: AB_2669628" "unprognostic (2.12e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-3)" "prognostic unfavorable (5.32e-4)" "unprognostic (7.23e-2)" "unprognostic (8.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-3)" "prognostic favorable (5.14e-11)" "unprognostic (8.75e-2)" "unprognostic (2.94e-2)" "unprognostic (8.32e-2)" "unprognostic (2.53e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.55e-3)" 14.6 17.0 10.7 12.0 11.8 6.7 14.3 17.1 13.7 10.9 15.4 14.1 15.4 10.3 14.1 14.1 10.2 9.3 30.7 11.2 12.2 24.2 20.5 10.9 14.9 10.8 11.7 12.3 18.8 22.5 13.4 16.4 11.2 12.8 15.4 30.1 15.9 13.4 52.9 12.3 12.1 10.7 10.9 11.4 15.7 6.3 12.2 8.7 16.3 49.4 14.8 13.2 11.5 11.4 36.7 21.0 24.7 46.3 15.9 14.4 54.8 16.6 19.3 20.5 18.5 80.9 16.9 21.2 67.3 14.6 32.2 21.8 25.6 31.6 22.0 26.8 44.9 33.6 16.4 93.7 23.0 38.7 30.0 22.8 24.7 20.9 16.7 23.8 22.2 27.2 49.5 0.0 22.6 28.9 37.1 35.3 64.6 20.6 18.9 0.2 4.3 48.4 90.5 37.1 39.3 23.7 28.1 84.9 46.5 72.0 43.3 26.3 9.6 9.1 13.8 18.9 30.8 37.4 68.1 29.4 11.3 45.4 38.3 3.4 16.8 7.3 11.6 20.2 14.9 14.4 12.4 12.5 24.8 11.9 13.4 12.6 1.9 15.3 18.8 14.8 11.5 12.1 10.7 11.8 17.1 13.7 11.2 12.2 10.8 11.7 11.2 10.9 12.2 11.4 10.5 35.3 20.0 18.6 18.0 7.1 13.6 18.8 16.5 33.5 15.7 10.4 55.6 20.0 16.4 20.2 39.6 46.5 23.3 13.6 52.8 22.6 0.6 15.7 11.5 11.3 9.6 17.1 33.7 19.1 24.6 14.8 13.3 12.9 12.0 23.3 11.4 14.4 21.9 50.5 35.6 15.4 22.4 15.8 10.0 0.7 12.2 14.8 7.2 9.4 19.6 21.8 16.5 15.1 16.5 15.9 14.9 16.6 19.7 14.7 20.0 40.7 14.4 43.6 19.7 9.2 12.9 5.4 11.6 22.7 11.2 25.3 13.1 27.2 22.3 15.7 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 254.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1139.3" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" 0.2 0.0 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 234.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 254.3 0.0 0.0 0.5 0.0 0.0 0.3 4.8 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1139.3 0.0 0.0 0.4 0.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.6 0.1 27.8 0.0 MS4A13 ENSG00000204979 "Membrane spanning 4-domains A13" Q5J8X5 11 60515392-60542721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 35 "testis: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 25.0;Late spermatids: 47.0;Spermatocytes: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045017, HPA063626" Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA045017: AB_10962976, HPA063626: AB_2685065" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 47.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MS4A15 ENSG00000166961 "Membrane spanning 4-domains A15" Q8N5U1 11 60756867-60776733 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lung: 43.9" "Cell type enriched" "Detected in some" 15 "Alveolar cells type 1: 96.1" "Cancer enhanced" "Detected in many" "lung cancer: 6.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Lineage enriched" "Detected in single" 12 "T-cells: 3.2" "Cell line enhanced" "Detected in some" "EFO-21: 1.2;HEL: 3.6;JURKAT: 1.6;MOLT-4: 1.6;U-266/70: 4.0;U-266/84: 2.1" "Region enriched" "Detected in some" 28 "olfactory bulb: 166.8" "Region enriched" "Detected in single" 26 "olfactory bulb: 20.2" HPA054563 Approved "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 19: Lung - Lung function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Cytosol "HPA054563: " "unprognostic (1.85e-1)" "unprognostic (4.31e-3)" "unprognostic (8.59e-2)" "unprognostic (5.89e-4)" "unprognostic (4.49e-1)" "unprognostic (1.09e-3)" "unprognostic (3.92e-3)" "unprognostic (5.43e-3)" "unprognostic (1.20e-1)" "unprognostic (7.30e-2)" "unprognostic (3.14e-1)" "unprognostic (1.04e-9)" "unprognostic (7.02e-2)" "unprognostic (8.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-1)" 0.3 0.2 0.2 0.4 0.2 0.1 2.2 0.3 0.4 0.3 0.2 0.3 1.0 1.2 0.3 0.4 1.0 0.2 0.3 0.7 0.2 0.1 0.0 43.9 0.5 0.4 0.2 1.8 0.1 0.0 0.0 0.7 0.4 0.3 0.6 0.4 0.1 1.2 0.0 0.0 2.2 1.6 0.1 0.3 0.4 0.6 0.2 3.8 0.3 0.0 1.8 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.0 3.2 0.2 0.2 0.2 0.3 0.4 0.7 0.2 0.4 0.2 0.4 0.1 0.2 0.3 0.2 96.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 MS4A2 "APY, FCER1B, IGER, MS4A1" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.6" "Cell type enriched" "Detected in some" 20 "granulocytes: 967.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 908 "basophil: 275.5" "Lineage enriched" "Detected in single" 1467 "granulocytes: 275.5" "Cell line enhanced" "Detected in some" "HEL: 2.7;THP-1: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 15.3" HPA059967 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" 2.6 0.2 0.3 2.4 0.3 0.9 2.7 0.5 0.5 6.3 0.6 4.9 5.5 4.2 3.7 4.8 0.9 8.2 0.6 0.3 0.3 0.5 0.4 12.6 1.1 0.4 0.3 0.1 0.5 0.3 0.1 0.3 0.4 3.0 5.4 0.0 1.8 2.4 2.9 2.5 6.7 4.1 0.3 0.2 5.3 1.0 0.3 1.2 0.1 1.2 1.8 3.8 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 275.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.4 0.3 0.3 0.5 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.3 0.5 0.1 0.0 30.9 0.0 0.3 0.0 0.9 0.0 0.0 0.3 0.1 0.1 0.5 0.0 6.8 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.3 0.0 46.7 0.1 0.0 0.1 1.1 0.0 0.1 967.4 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.7 0.4 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.2 MS4A3 "CD20L, HTM4" ENSG00000149516 "Membrane spanning 4-domains A3" Q96HJ5 11 60056587-60071115 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "bone marrow: 420.2" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 19.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 1478 "basophil: 2686.3" "Lineage enriched" "Detected in single" 4507 "granulocytes: 2686.3" "Cell line enhanced" "Detected in some" "HEL: 48.9;K-562: 94.2;NB-4: 109.8;THP-1: 319.0;U-937: 126.2" "Not detected" "Not detected" HPA019210 Supported Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA019210: AB_1854134" "unprognostic (6.37e-3)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.77e-1)" 0.1 0.0 0.0 0.3 0.0 420.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 4.5 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 48.9 0.0 0.0 0.0 17.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 319.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 126.2 0.0 2686.3 0.1 1.8 0.1 0.1 0.3 0.2 0.4 0.0 0.3 0.2 0.2 0.4 0.9 0.1 0.5 0.2 0.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 0.0 0.0 0.8 0.0 3.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "dendritic cells: 1.4;Erythroid cells: 1.3;Kupffer cells: 3.4;Macrophages: 5.4;Microglial cells: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.8" "Cell line enhanced" "Detected in many" "HMC-1: 8.1" HPA040075 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" 5.9 4.0 5.4 3.5 5.1 7.7 3.7 8.1 6.7 1.1 6.5 2.8 3.3 1.8 2.8 1.6 1.5 3.0 1.3 6.0 4.7 1.8 5.5 2.9 2.8 5.4 4.1 1.6 1.5 1.3 0.0 1.8 4.6 2.0 2.7 4.5 1.7 1.2 4.4 4.2 4.5 2.9 2.6 4.7 2.7 2.9 5.3 1.1 1.2 0.8 1.9 1.5 0.0 5.8 4.2 1.7 0.9 2.2 0.7 0.4 3.2 1.7 0.2 0.2 0.3 1.2 1.8 1.3 1.7 0.1 1.2 3.4 0.3 0.2 0.3 5.0 1.1 2.3 3.5 2.0 0.6 1.3 8.1 0.5 1.5 0.5 0.7 0.9 0.2 1.8 2.4 4.2 0.2 1.6 1.9 2.6 1.8 2.0 1.3 1.6 1.7 1.8 0.5 2.1 1.3 2.2 4.9 1.8 2.4 2.0 2.4 2.4 1.1 1.7 7.8 4.8 1.6 5.6 4.7 1.9 0.9 2.8 1.5 17.8 1.4 0.2 0.4 1.6 0.3 0.5 0.3 0.2 2.5 0.7 0.3 0.4 2.7 0.9 1.4 1.4 0.2 0.3 5.4 5.1 8.1 6.7 6.0 4.7 5.4 4.1 4.6 2.6 5.3 5.8 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 5.4 0.0 1.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MS4A6E ENSG00000166926 "Membrane spanning 4-domains A6E" Q96DS6 11 60334831-60396596 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 35.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 1211.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076623 Approved Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA076623: AB_2686809" "unprognostic (2.58e-1)" "unprognostic (3.35e-1)" "unprognostic (3.47e-1)" "unprognostic (6.81e-3)" "unprognostic (4.55e-4)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" 2.1 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 35.6 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1211.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 114.8 6.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 709929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 73985.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" 27287.7 50118.4 114427.0 5960.9 114629.6 9211.1 23112.5 102567.5 164780.5 8637.9 123709.0 47542.8 18239.3 10045.0 10813.1 24529.5 11015.1 5914.4 210840.8 108795.0 110116.5 112074.1 105449.6 14032.6 6314.3 129884.9 115346.3 7950.6 24515.9 29782.0 16861.9 10397.8 125082.8 25688.4 24989.1 8983.3 21379.6 12907.0 93258.6 22997.0 36121.9 9693.6 102620.8 18194.3 45409.4 14516.5 123032.8 6034.4 16877.7 109930.2 7889.2 21068.8 13184.5 102646.5 6276.2 9796.4 12777.6 12396.3 25548.5 9745.3 9393.2 7927.6 6429.8 4420.4 6584.3 10616.0 13681.5 12924.1 6467.6 11751.8 4522.1 23074.6 1724.1 16319.1 5925.8 10089.3 8726.0 9297.7 73985.8 20756.8 5543.0 7919.2 9987.0 14433.8 23568.7 2276.3 8072.8 14337.8 4979.3 12668.7 8862.9 12216.0 12212.6 13490.3 5804.8 22519.7 3353.4 12256.7 6160.6 5998.2 3899.6 10866.7 17578.2 17096.2 4758.2 7830.6 6527.3 15842.4 11881.3 18742.2 11084.6 31596.4 12345.0 10576.0 9043.3 10116.0 5740.6 6151.2 6563.0 7590.8 5638.0 15586.1 7129.7 20953.0 13541.7 15753.7 5586.8 8887.6 6782.0 11844.8 6189.5 6338.9 6316.7 10947.0 6386.1 7947.1 5329.9 6846.5 10055.3 8426.1 5367.4 7670.7 114427.0 114629.6 102567.5 164780.5 108795.0 110116.5 129884.9 115346.3 125082.8 102620.8 123032.8 102646.5 4337.7 1445.5 1999.8 0.0 11825.3 6754.0 8961.4 22171.6 22140.9 0.0 11994.6 16742.4 709929.9 18464.2 10323.3 18597.6 0.0 0.0 7569.1 29582.2 3709.5 3684.4 1119.7 12108.5 6979.9 16215.0 6396.9 27238.9 0.0 4873.7 0.0 10942.5 19089.4 20683.3 2144.6 17185.5 15141.7 53416.5 0.0 0.0 0.0 17158.1 14290.0 26774.7 4814.0 5284.9 7663.3 9292.7 5140.4 0.0 7967.0 0.0 6828.1 0.0 0.0 4709.1 15133.6 5123.0 14109.6 5949.4 40280.5 22569.2 7617.1 0.0 7060.4 9361.8 14171.2 7120.5 8965.1 26952.2 6702.8 0.0 8863.0 13639.8 19371.4 14261.8 MTCH1 "CGI-64, PSAP, SLC25A49" ENSG00000137409 "Mitochondrial carrier 1" Q9NZJ7 6 36968141-36986298 "Predicted membrane proteins, Transporters" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 1002.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015971 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015971: AB_1854171" "unprognostic (3.17e-2)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.29e-1)" "unprognostic (2.88e-2)" "unprognostic (1.54e-1)" "unprognostic (7.49e-2)" "unprognostic (1.35e-3)" "prognostic favorable (1.16e-7)" "unprognostic (1.32e-2)" "unprognostic (3.11e-1)" "unprognostic (6.68e-2)" "unprognostic (4.70e-2)" 151.0 279.7 314.7 97.4 331.9 194.1 140.2 290.1 341.2 194.5 257.9 151.7 93.7 136.3 312.1 130.8 154.2 99.6 259.7 326.1 333.3 168.1 117.2 202.5 95.4 306.1 310.3 177.3 165.4 142.1 284.8 106.0 333.1 183.1 96.4 92.0 144.2 196.5 133.7 176.6 125.2 114.7 305.1 148.7 156.2 81.1 349.0 88.2 364.1 89.0 88.6 156.4 166.2 340.8 196.3 130.8 173.3 214.0 254.7 171.9 99.0 225.3 208.2 312.1 322.1 218.0 118.3 97.1 197.7 379.8 301.8 167.1 189.2 181.8 360.2 104.5 183.9 101.3 223.4 165.4 184.1 65.7 92.1 194.5 140.5 289.7 140.5 271.8 269.3 133.0 186.1 97.5 199.8 221.4 134.3 149.8 170.1 175.2 147.5 122.9 135.4 102.6 169.1 160.5 278.8 119.9 163.9 141.2 206.8 173.6 182.5 181.9 299.6 311.5 246.1 241.3 247.3 85.3 92.5 1002.9 112.1 179.4 250.1 11.0 34.7 45.4 14.5 34.9 13.5 18.8 27.5 29.2 31.1 31.2 26.2 15.4 37.8 18.4 44.7 17.3 22.4 17.3 314.7 331.9 290.1 341.2 326.1 333.3 306.1 310.3 333.1 305.1 349.0 340.8 133.7 48.1 99.1 47.3 79.1 113.7 177.1 138.6 71.7 0.0 152.7 125.2 162.5 117.2 101.2 69.9 0.0 183.5 91.8 149.9 168.3 213.0 8.2 99.0 139.4 112.3 149.3 67.6 54.1 170.0 224.0 163.4 94.3 177.3 29.2 193.6 85.6 50.9 189.2 0.0 52.8 133.0 105.8 97.2 150.6 16.3 138.2 109.5 136.9 44.0 173.2 0.0 55.6 28.1 106.4 181.7 162.3 132.4 57.6 255.0 144.3 129.4 68.0 0.0 52.6 108.8 133.5 18.5 46.4 86.2 123.5 248.3 85.8 118.5 145.1 208.5 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 MTX1 "MTX, MTXN" ENSG00000173171 "Metaxin 1" Q13505 1 155208695-155213824 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 601.3;Late spermatids: 1473.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011543 Uncertain Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA011543: AB_1853824" "unprognostic (2.57e-1)" "unprognostic (9.51e-3)" "unprognostic (3.27e-1)" "unprognostic (5.98e-3)" "unprognostic (1.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.28e-2)" "unprognostic (1.71e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-2)" 29.3 33.2 23.9 16.1 24.5 39.1 28.2 25.2 29.2 22.3 29.2 25.9 18.9 25.3 17.8 33.0 31.0 13.1 22.1 23.2 24.2 34.1 44.8 22.9 19.6 24.8 24.7 17.6 27.7 37.7 20.3 20.8 24.5 22.1 18.8 3.7 31.6 21.7 17.5 25.5 23.0 18.6 24.7 29.3 28.1 90.3 24.8 20.9 24.4 16.7 21.2 20.7 21.2 25.3 54.3 87.6 27.3 39.3 49.9 44.8 86.4 27.4 55.0 79.4 55.1 109.5 88.2 44.3 88.2 63.4 25.2 52.8 40.6 77.4 28.8 32.9 95.4 28.3 64.0 107.1 78.8 52.5 38.0 57.5 71.2 82.2 54.9 30.4 71.2 64.4 58.1 21.5 47.9 131.7 59.6 65.9 54.7 76.5 100.2 48.3 17.2 105.4 73.1 46.2 44.5 55.3 34.0 106.3 31.0 41.6 86.2 84.1 30.0 37.8 42.6 25.4 46.9 41.1 37.3 46.2 50.1 26.8 41.3 32.8 69.0 17.4 24.2 38.3 23.2 41.6 29.6 25.7 60.8 37.7 29.3 26.5 114.2 34.6 22.2 32.9 39.0 40.6 23.9 24.5 25.2 29.2 23.2 24.2 24.8 24.7 24.5 24.7 24.8 25.3 26.0 9.6 17.0 4.9 28.9 20.3 42.0 91.3 26.7 0.0 41.8 42.4 1.1 27.1 45.1 35.0 0.0 107.5 17.1 36.5 97.8 80.1 601.3 56.6 35.1 24.7 19.8 14.7 2.8 84.7 130.7 33.6 40.8 30.1 26.6 42.2 23.9 54.4 97.3 0.0 3.6 42.3 54.9 37.1 23.3 1473.9 43.2 38.9 49.8 1.0 65.1 0.0 37.0 3.0 4.8 72.7 48.4 39.5 39.3 41.6 44.3 144.6 61.2 0.0 46.0 29.2 58.4 105.2 52.9 34.9 21.0 88.7 22.5 43.9 54.6 42.6 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Horizontal cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" 5.3 13.1 32.9 4.5 32.2 3.9 7.5 32.2 37.8 23.5 30.2 20.5 2.4 23.8 7.8 5.2 25.2 4.0 11.6 33.8 32.5 25.5 6.5 10.5 3.8 29.8 32.9 20.6 8.4 10.7 47.1 6.9 28.7 14.9 2.1 8.4 5.3 7.8 3.0 5.7 8.5 8.8 27.8 7.1 10.1 11.6 36.2 53.6 20.0 1.2 2.9 11.8 10.8 29.0 8.2 27.6 32.1 59.8 12.9 16.3 19.4 29.6 35.5 32.5 46.3 9.7 26.6 3.1 10.3 19.5 16.4 10.6 20.8 18.8 20.0 32.9 168.2 26.1 41.0 21.9 23.3 19.4 25.8 22.7 6.5 22.7 6.2 65.5 24.3 46.9 32.3 9.1 19.7 10.0 33.1 29.7 44.2 16.4 13.1 32.7 19.9 12.6 78.2 15.3 93.4 64.5 11.9 17.8 28.9 12.2 14.5 20.0 28.5 11.8 31.5 1.7 24.5 18.0 7.4 13.7 26.7 3.3 30.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 32.9 32.2 32.2 37.8 33.8 32.5 29.8 32.9 28.7 27.8 36.2 29.0 4.0 6.4 3.2 9.1 3.8 2.9 6.7 4.4 4.6 62.6 11.7 13.8 4.1 5.7 2.6 29.5 35.5 13.3 3.8 1.2 15.6 14.5 1.5 41.7 31.7 7.2 12.7 10.3 12.9 1.1 8.3 10.4 3.1 9.7 0.0 11.5 3.9 3.6 2.9 148.0 13.1 2.1 4.1 0.8 2.4 3.1 11.8 1.7 5.4 2.8 2.3 39.6 1.0 7.1 2.8 4.3 0.4 10.5 2.7 4.4 0.7 3.7 18.1 39.9 0.0 13.8 12.1 4.2 3.9 0.7 0.6 6.0 2.6 9.7 1.1 1.9 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 732.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 2565.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Hep G2: 10.7" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.1 0.3 1.1 0.1 0.5 0.1 0.2 0.1 0.7 0.2 0.0 1.1 4.6 0.1 0.0 0.0 1.2 0.6 0.1 0.8 0.8 732.4 82.7 0.2 0.0 0.6 0.3 1.3 0.2 0.0 0.6 0.0 0.1 0.2 0.1 1.8 0.1 0.1 0.0 0.0 7.2 0.1 0.4 1.1 0.6 0.5 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.1 0.7 0.8 0.8 0.6 0.3 0.1 0.4 1.0 0.8 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 36.8 0.0 0.0 0.0 0.3 187.9 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.9 51.1 0.0 0.0 0.0 1.1 0.0 1.0 0.4 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 61.3 2565.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.6 0.1 NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.5;retina: 65.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1016.1;Inhibitory neurons: 953.0;Oligodendrocyte precursor cells: 466.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 33.1;SH-SY5Y: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" 2.4 7.2 7.7 1.5 10.7 0.3 4.9 19.0 23.5 3.5 2.8 5.8 1.4 6.1 2.2 3.3 5.5 3.4 6.9 17.4 2.8 4.1 0.6 2.0 1.6 4.1 0.1 6.2 3.1 7.1 8.3 0.6 4.8 6.6 2.5 65.7 4.7 8.4 5.6 1.5 2.5 6.5 0.4 3.2 2.7 3.5 0.0 5.6 6.3 5.7 1.2 3.6 2.8 4.5 0.0 4.5 10.9 6.1 0.7 0.1 0.3 7.0 10.8 7.9 6.6 0.1 1.0 3.0 0.0 12.9 4.7 0.3 3.7 1.5 16.3 1.4 3.6 0.0 3.4 1.2 0.5 1.9 4.7 2.1 1.2 0.1 0.7 33.1 1.8 1.2 0.1 17.6 1.1 1.9 1.1 0.0 4.6 6.2 2.0 1.1 4.7 0.9 9.3 2.1 6.2 80.1 5.4 0.1 3.6 8.1 2.0 0.4 0.1 2.0 1.2 0.0 1.6 1.9 0.5 1.3 5.4 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 7.7 10.7 19.0 23.5 17.4 2.8 4.1 0.1 4.8 0.4 0.0 4.5 19.7 28.9 9.2 132.9 5.2 1.0 5.3 2.7 1.2 124.8 5.0 6.5 51.8 11.5 14.1 9.2 146.0 0.1 4.4 0.3 1.9 9.2 19.3 5.6 18.4 10.1 22.9 0.8 1016.1 1.8 0.1 12.3 2.0 0.6 25.2 20.7 11.0 0.3 0.9 47.1 953.0 2.1 6.1 3.5 3.9 13.6 17.7 3.5 7.2 150.9 1.2 69.1 0.0 466.9 163.7 2.3 0.1 19.2 5.8 8.5 0.2 7.6 56.5 87.0 6.6 22.2 13.1 8.5 8.0 0.3 0.9 0.0 1.2 11.9 1.1 13.5 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 60000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA020449: AB_1854327" "unprognostic (7.92e-3)" "unprognostic (1.24e-2)" "unprognostic (3.35e-2)" "unprognostic (8.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.12e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (5.06e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (2.41e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" 51.5 44.3 48.3 25.6 57.6 1.0 48.7 45.9 58.7 55.0 43.5 59.4 55.9 52.8 52.9 81.3 42.1 42.3 71.8 72.8 47.2 70.6 41.2 40.3 10.3 36.9 46.2 45.0 43.0 88.4 34.0 50.1 41.9 55.4 48.5 58.4 43.2 65.4 89.5 51.1 51.3 74.1 37.9 20.5 57.7 32.1 45.4 15.2 85.4 87.3 24.6 60.8 49.1 44.4 107.1 66.0 99.1 63.6 136.8 132.3 110.2 136.5 123.4 90.6 113.3 102.9 89.2 0.6 89.2 163.1 136.1 99.0 84.6 128.6 150.2 25.7 66.1 23.7 69.4 85.4 140.5 0.2 19.9 99.5 155.4 131.4 213.8 123.7 146.3 6.4 58.7 0.4 173.3 68.5 2.3 0.4 102.1 85.8 112.7 6.9 108.2 0.4 127.9 141.9 72.7 69.3 123.6 97.0 130.0 156.2 52.0 0.7 160.0 153.2 86.1 87.1 84.7 13.4 26.5 0.5 118.6 0.1 79.5 0.4 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 48.3 57.6 45.9 58.7 72.8 47.2 36.9 46.2 41.9 37.9 45.4 44.4 75.3 48.1 47.1 129.9 2.1 87.2 64.7 50.1 38.1 83.9 54.2 39.9 103.9 48.6 57.0 80.9 70.9 33.1 3.7 52.4 27.4 54.3 4.5 56.4 57.9 82.8 50.4 0.8 174.2 62.0 50.2 62.3 49.5 106.6 14.0 43.8 72.8 42.4 5.3 122.8 143.9 58.8 50.8 5.5 23.1 9.0 78.6 4.6 55.2 72.1 0.7 90.7 6.2 136.7 98.8 95.7 69.8 105.3 1.4 116.8 64.3 66.4 40.2 59.9 59.2 86.1 84.1 42.4 28.7 83.6 112.5 52.1 5.5 55.6 55.5 117.3 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 121.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019267, HPA050005" Enhanced "Plasma membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "CAB019267: , HPA050005: AB_2680988" "unprognostic (1.55e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.79e-1)" "unprognostic (9.64e-3)" "unprognostic (5.50e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.20e-5)" "unprognostic (1.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" 18.6 17.7 25.5 6.3 28.5 5.9 17.0 16.4 47.6 14.9 2.4 13.7 10.0 12.9 11.4 11.1 16.3 12.4 37.5 26.3 23.0 19.3 14.3 16.5 8.5 23.1 16.4 31.1 11.8 121.9 20.1 11.1 22.5 17.5 9.8 11.3 14.1 15.8 12.6 19.8 12.5 11.7 13.1 11.5 11.6 16.4 23.7 6.3 13.6 10.0 7.0 12.6 14.6 29.3 20.9 18.0 18.0 18.6 24.0 14.5 25.0 20.5 22.8 22.2 28.2 26.6 12.4 15.3 10.9 12.2 25.4 13.8 23.2 27.1 12.7 17.3 28.3 27.4 73.2 21.5 20.9 18.8 29.6 14.0 23.3 30.9 19.3 25.2 12.8 19.1 9.5 19.8 18.1 15.3 17.1 15.8 21.0 20.6 31.5 8.6 8.3 25.8 12.3 21.2 18.7 15.1 21.4 19.9 17.4 16.3 17.7 22.7 7.2 19.0 21.3 22.8 27.5 17.7 14.1 17.0 21.7 24.6 29.8 0.6 2.9 0.1 2.1 3.4 1.5 2.9 2.4 2.4 3.6 1.4 3.5 2.4 0.2 3.4 1.8 5.2 2.9 2.9 25.5 28.5 16.4 47.6 26.3 23.0 23.1 16.4 22.5 13.1 23.7 29.3 15.9 0.0 6.9 7.2 2.9 2.5 3.7 8.1 1.8 9.2 3.8 5.5 17.0 5.7 4.0 1.8 12.5 9.6 4.5 10.8 5.9 7.0 2.4 4.7 5.5 8.1 8.4 4.8 11.8 4.6 10.5 5.4 6.6 5.8 5.7 7.6 23.6 6.4 8.6 11.8 10.9 6.0 6.1 6.5 6.1 2.5 18.3 6.4 1.8 1.9 4.5 3.5 0.0 2.5 8.3 7.5 6.2 47.4 3.9 2.3 13.8 7.6 3.9 6.3 13.1 4.0 6.4 5.6 18.4 2.8 1.7 8.2 3.3 8.6 8.7 2.3 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 286.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 539.9;Langerhans cells: 741.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1668.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 1668.9" "Cell line enhanced" "Detected in many" "Hep G2: 197.5;MCF7: 191.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "HPA045063: AB_10964133" "unprognostic (1.23e-2)" "unprognostic (8.25e-3)" "unprognostic (3.64e-3)" "unprognostic (1.40e-2)" "unprognostic (8.18e-2)" "unprognostic (1.28e-2)" "unprognostic (4.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.82e-2)" "unprognostic (9.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (7.46e-3)" 60.9 129.8 51.0 39.9 48.9 286.9 53.0 47.9 58.7 47.6 50.2 60.1 27.0 36.5 20.2 25.7 47.6 39.2 64.0 44.2 51.9 100.4 118.0 65.0 41.5 54.5 53.2 35.9 35.0 137.7 59.2 66.6 53.3 58.9 16.5 6.1 77.3 56.2 38.0 80.4 37.6 36.0 57.6 89.9 42.5 37.6 57.2 30.5 71.4 30.0 19.6 100.5 37.9 59.2 45.0 68.2 13.2 30.0 47.4 19.1 51.6 30.2 85.9 43.5 26.7 29.5 15.5 0.6 15.0 29.7 47.6 44.8 14.7 84.6 9.4 103.3 28.7 6.8 17.2 197.5 163.7 4.8 13.8 62.5 80.9 41.1 22.5 132.4 41.3 16.3 5.0 49.6 9.9 191.1 13.9 13.8 18.7 51.9 53.0 24.6 10.3 79.0 35.0 18.6 4.3 18.4 67.3 105.4 41.9 22.0 81.9 31.3 31.1 15.8 44.6 33.2 22.9 26.2 11.4 1.0 48.2 14.8 12.1 152.9 313.3 824.9 69.8 315.4 94.5 7.8 65.0 59.3 75.9 2.4 76.5 55.1 1668.9 44.7 355.8 10.7 73.8 219.1 51.0 48.9 47.9 58.7 44.2 51.9 54.5 53.2 53.3 57.6 57.2 59.2 15.7 28.9 41.6 6.5 24.3 114.6 75.8 273.0 130.3 1.8 117.8 96.6 31.6 62.9 80.7 40.5 0.0 128.3 45.8 19.4 129.1 95.2 3.9 22.9 20.9 46.9 18.0 3.0 3.4 101.7 78.3 64.9 20.9 24.5 47.0 13.8 23.6 48.5 539.9 1.7 3.9 21.3 111.9 176.9 741.7 21.1 42.0 278.1 147.7 18.7 214.9 76.1 33.0 3.0 1.7 68.7 23.7 72.6 32.5 60.3 75.5 240.6 18.8 3.8 13.1 45.7 53.3 0.9 11.4 36.3 135.7 73.3 54.7 4.5 19.7 76.9 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NKAIN1 "FAM77C, FLJ12650" ENSG00000084628 "Sodium/potassium transporting ATPase interacting 1" Q4KMZ8 1 31179745-31239887 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adrenal gland: 24.2;brain: 19.9;skeletal muscle: 19.4;tongue: 11.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 43.9" "Group enriched" "Detected in many" 5 "breast cancer: 17.2;glioma: 4.6;prostate cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.2;AN3-CA: 35.8;NTERA-2: 92.7;SCLC-21H: 27.3;SH-SY5Y: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006873 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA006873: AB_1848410" "unprognostic (1.58e-2)" "unprognostic (7.99e-2)" "unprognostic (8.54e-2)" "unprognostic (6.11e-5)" "unprognostic (6.59e-2)" "unprognostic (1.24e-1)" "unprognostic (4.30e-4)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (2.78e-2)" "unprognostic (2.01e-2)" "unprognostic (8.07e-2)" "unprognostic (6.31e-9)" "unprognostic (1.00e-2)" "unprognostic (8.83e-3)" "unprognostic (1.62e-4)" "unprognostic (5.50e-2)" 0.1 24.2 8.1 0.2 15.6 0.0 0.4 17.3 11.6 0.3 3.1 0.3 0.1 0.6 3.4 0.6 0.1 0.0 0.0 11.5 10.6 0.2 0.0 0.0 0.0 17.9 16.4 0.1 0.2 0.6 2.2 0.3 19.9 1.0 0.1 1.5 0.4 0.3 19.4 1.7 0.1 0.2 6.8 0.0 0.1 0.3 12.2 0.2 0.0 11.9 0.0 0.0 0.5 18.6 0.0 0.4 21.2 35.8 0.2 0.0 0.3 0.1 0.0 0.4 0.1 0.4 0.2 0.0 0.7 0.4 0.4 0.0 5.3 0.0 0.1 0.0 1.5 0.0 0.3 0.3 0.2 0.4 0.1 0.1 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.3 0.8 92.7 0.0 0.9 0.0 0.3 0.1 0.1 3.6 27.3 43.9 1.0 0.3 2.5 2.4 9.6 0.4 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 15.6 17.3 11.6 11.5 10.6 17.9 16.4 19.9 6.8 12.2 18.6 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.9 0.2 0.0 0.1 1.1 0.0 0.0 0.0 3.6 0.0 0.3 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 3.3 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.5 43.9 0.1 0.0 0.0 0.0 0.3 0.0 0.8 0.1 0.5 0.0 0.3 0.3 0.8 1.2 0.3 1.4 0.4 0.0 0.1 0.0 0.2 NKAIN3 "FAM77D, FLJ39630, NKAIN3-IT1" ENSG00000185942 "Sodium/potassium transporting ATPase interacting 3" Q8N8D7 8 62248591-63014000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "brain: 18.9" "Group enriched" "Detected in some" 6 "Astrocytes: 1258.6;Oligodendrocyte precursor cells: 811.8" "Cancer enriched" "Detected in single" 5 "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.2;SCLC-21H: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018833 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA018833: AB_2669943" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-3)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (3.22e-2)" "unprognostic (3.15e-2)" "unprognostic (1.58e-1)" 0.2 1.7 18.9 0.3 11.8 0.9 0.3 0.8 9.9 0.6 0.0 0.4 0.3 0.4 0.7 0.2 0.2 0.3 0.3 16.1 10.6 0.4 2.0 0.2 0.3 3.7 11.2 0.4 0.3 0.7 0.0 0.2 2.2 0.3 0.4 1.7 1.2 0.4 0.6 0.7 0.4 0.2 1.4 0.4 0.3 0.4 16.1 0.1 0.2 0.1 0.1 0.2 0.0 4.8 0.4 0.6 2.2 0.3 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.6 0.5 0.3 0.2 0.2 0.2 0.5 0.1 0.1 0.4 0.1 0.9 1.2 0.3 0.1 0.5 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.5 1.3 0.1 0.2 0.3 0.5 0.8 0.4 1.1 1.9 0.3 0.2 0.0 0.6 3.7 0.3 0.3 0.4 0.2 0.6 0.3 0.4 0.4 0.5 0.5 0.4 0.3 0.6 0.5 0.2 0.6 0.4 1.2 0.9 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.2 0.5 0.2 0.2 0.2 0.1 0.0 18.9 11.8 0.8 9.9 16.1 10.6 3.7 11.2 2.2 1.4 16.1 4.8 0.0 0.0 0.0 1258.6 0.0 0.4 0.1 0.0 0.0 10.4 1.3 1.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.2 6.3 0.0 0.0 0.0 35.7 0.7 0.1 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 168.5 0.0 0.0 0.0 0.0 4.2 0.3 0.0 1.8 21.5 0.0 0.0 0.0 811.8 3.8 0.6 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.2 0.0 7.6 0.1 0.0 0.4 0.3 0.0 0.1 0.0 0.2 0.0 0.2 NKAIN4 "bA261N11.2, C20orf58, FAM77A" ENSG00000101198 "Sodium/potassium transporting ATPase interacting 4" Q8IVV8 20 63240784-63272694 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 68.1;choroid plexus: 20.3;kidney: 52.2" "Group enriched" "Detected in some" 5 "Muller glia cells: 80.8;Oligodendrocyte precursor cells: 76.4;Proximal tubular cells: 264.8" "Cancer enriched" "Detected in many" 6 "glioma: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 24.9;MOLT-4: 42.8;SK-MEL-30: 9.3;SuSa: 29.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029876 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA029876: AB_10602038" "unprognostic (1.26e-1)" "unprognostic (4.27e-1)" "unprognostic (6.07e-5)" "prognostic unfavorable (3.14e-4)" "unprognostic (6.65e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-3)" "unprognostic (1.94e-1)" "unprognostic (3.62e-2)" "unprognostic (2.69e-2)" "unprognostic (1.83e-2)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.44e-4)" "unprognostic (5.66e-2)" "unprognostic (6.74e-2)" "unprognostic (4.01e-1)" 0.1 0.8 41.3 0.2 41.0 0.1 0.1 28.7 68.1 2.3 20.3 1.7 0.3 0.4 0.4 0.0 0.3 0.1 0.0 45.7 44.7 52.2 0.0 0.1 0.0 39.1 40.3 0.1 0.1 0.0 2.4 2.8 39.9 0.1 0.1 3.1 0.1 0.1 0.0 0.4 0.4 0.0 37.5 0.1 0.3 2.2 40.3 1.2 0.8 0.1 0.0 0.1 0.6 36.1 0.1 2.0 7.5 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 1.3 0.8 0.0 3.9 0.0 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 42.8 0.0 5.2 0.0 0.1 7.8 0.0 0.7 0.3 0.0 0.0 0.0 0.5 0.1 9.3 29.5 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.5 4.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 41.0 28.7 68.1 45.7 44.7 39.1 40.3 39.9 37.5 40.3 36.1 0.0 0.0 0.0 23.8 1.9 0.3 0.0 1.7 0.0 2.6 0.0 0.1 0.3 0.0 0.1 11.0 0.0 3.3 0.0 0.0 5.9 0.5 0.7 0.2 0.2 0.2 0.0 0.0 0.1 0.6 3.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.9 5.3 1.5 0.0 1.0 0.0 80.8 0.0 76.4 0.1 4.2 0.0 0.0 0.0 0.0 0.0 264.8 0.1 1.9 0.0 0.0 0.3 0.4 6.0 0.0 0.0 2.3 0.8 0.1 0.0 0.1 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149750-45160815 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 5.0;Spermatocytes: 2.4;Suprabasal keratinocytes: 1.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 1.4;SiHa: 1.2;U-266/70: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA043339 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" 0.1 0.1 0.4 0.0 0.1 0.2 0.5 0.2 0.4 1.3 0.0 0.0 0.0 0.1 0.2 1.0 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.0 0.5 0.8 0.0 0.3 0.5 0.5 0.1 15.9 0.1 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.2 3.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.3 0.2 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 1.2 0.7 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.4 0.1 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.0 0.6 0.9 0.2 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.1 5.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.2 0.5 1.3 0.1 0.0 0.2 0.0 0.1 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 70.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 273.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" 17.5 76.7 35.1 16.9 69.6 42.6 20.0 55.3 47.8 16.7 28.6 13.7 14.5 16.7 15.0 20.5 13.4 15.3 11.5 41.1 44.3 16.8 15.2 29.0 20.4 73.3 55.8 16.0 11.9 72.6 15.0 27.8 66.6 13.1 12.0 28.0 36.8 13.2 22.9 24.3 17.8 15.1 49.8 17.1 20.4 13.7 55.8 12.2 11.8 14.1 15.6 15.8 18.0 110.6 21.5 41.4 17.8 29.3 55.8 44.6 40.7 37.3 81.1 38.8 84.3 28.1 30.7 18.4 28.0 55.0 132.8 59.3 22.6 63.2 35.2 15.0 17.9 6.8 35.7 63.2 79.2 25.0 28.5 42.2 61.3 81.7 273.2 76.8 40.3 20.7 20.1 47.5 44.2 32.4 10.6 14.9 12.5 24.4 37.3 15.3 28.1 45.0 88.8 51.9 7.5 14.5 44.6 62.0 54.3 27.7 15.9 19.5 50.0 81.1 15.3 32.4 32.3 29.7 97.1 12.2 177.7 21.8 37.1 4.4 9.0 8.8 29.7 8.7 20.5 5.0 12.4 20.7 4.0 6.7 5.5 15.0 7.9 10.5 13.8 70.9 17.4 10.6 35.1 69.6 55.3 47.8 41.1 44.3 73.3 55.8 66.6 49.8 55.8 110.6 18.4 25.6 56.1 32.7 9.6 9.3 34.1 16.5 8.0 6.7 10.5 9.4 4.4 11.5 21.8 9.2 18.8 15.1 61.0 24.8 0.0 11.2 1.2 23.3 12.2 16.4 3.6 2.5 23.8 15.1 7.8 13.0 15.3 53.9 10.8 31.6 6.8 9.8 28.9 3.3 20.2 7.3 2.0 11.9 6.5 1.5 9.0 21.0 12.4 59.0 7.2 15.1 25.7 39.2 182.0 34.4 22.6 10.5 15.6 41.5 8.3 5.4 10.0 12.7 0.0 10.3 14.4 13.9 25.1 17.6 14.5 23.8 19.1 52.4 7.6 64.0 NPIPB11 ENSG00000254206 "Nuclear pore complex interacting protein family member B11" E5RHQ5 16 29381354-29404029 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Early spermatids: 17.5;Intestinal goblet cells: 9.4;Undifferentiated cells: 9.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (6.82e-2)" "unprognostic (2.99e-1)" "unprognostic (1.93e-3)" "unprognostic (1.42e-1)" "unprognostic (1.14e-1)" "unprognostic (6.92e-3)" "unprognostic (3.06e-1)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (5.57e-4)" "unprognostic (7.41e-2)" "unprognostic (2.94e-6)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "unprognostic (5.96e-3)" "unprognostic (4.79e-5)" 2.8 1.6 6.0 2.8 5.4 4.7 2.5 7.2 8.4 2.9 6.3 2.7 2.0 2.1 3.2 2.1 3.1 1.8 2.3 5.6 6.7 3.3 4.2 2.5 6.0 5.5 4.6 3.3 2.0 0.9 2.6 1.2 5.4 2.8 1.7 5.8 2.2 0.6 4.4 6.7 3.7 0.9 3.4 4.4 2.7 4.9 5.8 2.0 3.2 0.9 1.1 2.3 2.5 6.6 1.5 1.2 2.2 3.2 1.6 1.2 2.9 1.4 0.6 1.2 0.5 1.7 2.9 9.0 2.1 0.7 0.5 2.6 1.8 2.1 1.2 2.2 2.4 2.1 4.4 2.8 0.8 2.6 4.9 0.7 1.6 1.3 1.8 2.5 0.6 2.4 2.7 2.6 1.1 3.5 2.2 8.3 3.8 0.9 2.7 3.3 0.9 3.0 1.3 1.1 2.9 1.4 0.4 2.0 1.1 6.8 1.1 3.3 3.0 3.0 1.3 2.1 1.9 2.5 1.7 7.3 1.7 3.3 2.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.5 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 6.0 5.4 7.2 8.4 5.6 6.7 5.5 4.6 5.4 3.4 5.8 6.6 1.4 9.6 5.6 3.6 4.2 0.0 0.1 0.3 0.6 0.2 1.5 0.9 2.5 1.5 2.6 0.0 0.0 0.3 3.7 8.8 0.0 1.2 17.5 0.6 0.5 2.6 7.2 1.3 4.6 0.8 0.2 1.8 3.6 0.6 5.1 0.4 0.4 0.2 0.3 5.0 5.4 9.4 0.0 0.0 0.0 5.9 0.3 1.6 0.0 1.0 1.5 0.1 5.2 2.5 4.2 1.9 5.9 0.7 2.7 0.1 3.7 0.3 2.3 0.3 0.0 0.5 1.0 0.8 0.1 0.5 0.0 0.4 4.4 0.3 9.8 0.0 NPIPB12 ENSG00000169203 "Nuclear pore complex interacting protein family member B12" F8W0I5 16 29483642-29505999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 198.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.5;granulocytes: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 29.3" "Group enriched" "Detected in all" 4 "B-cells: 8.4;granulocytes: 29.3;NK-cells: 14.2" "Cell line enhanced" "Detected in all" "NB-4: 166.4" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (3.83e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "unprognostic (7.92e-2)" "unprognostic (1.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (5.20e-2)" "unprognostic (2.42e-1)" "unprognostic (6.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.28e-7)" "unprognostic (3.32e-2)" "unprognostic (4.11e-2)" "unprognostic (2.33e-1)" "unprognostic (2.14e-4)" 25.4 21.7 135.6 40.5 135.5 63.7 21.9 136.7 198.1 30.8 109.8 27.5 24.0 24.0 38.5 24.8 27.5 24.8 29.2 127.2 143.6 31.8 58.2 27.5 57.0 128.7 140.4 26.9 24.2 15.1 26.3 20.4 128.8 33.3 25.6 32.2 34.5 20.0 44.3 108.9 33.6 19.7 105.7 51.2 23.5 29.1 137.3 28.1 28.8 15.5 29.8 26.7 24.2 131.2 26.2 26.7 20.6 52.8 24.7 14.7 40.0 15.7 4.4 7.8 6.7 23.1 52.5 43.8 27.4 13.1 15.4 34.5 35.2 25.3 10.7 28.1 25.6 33.3 36.0 46.5 22.2 36.1 61.5 23.0 19.5 17.6 18.5 19.9 9.0 24.3 34.5 37.2 12.7 42.6 26.6 166.4 31.5 17.6 19.3 61.6 9.1 42.7 19.1 18.6 21.9 15.4 8.9 36.5 22.5 9.2 18.7 43.4 22.4 49.9 19.2 34.9 30.2 19.5 21.3 42.7 20.3 63.9 23.9 29.3 3.5 1.4 3.9 1.2 1.0 3.7 2.3 2.7 2.4 8.4 3.1 2.1 9.5 14.2 3.0 2.6 1.8 1.3 135.6 135.5 136.7 198.1 127.2 143.6 128.7 140.4 128.8 105.7 137.3 131.2 0.0 3.2 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 NPIPB13 ENSG00000198064 "Nuclear pore complex interacting protein family, member B13" A6NJU9 16 30222937-30254510 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 16.0;Alveolar cells type 2: 10.6;Club cells: 7.4;granulocytes: 12.6;Respiratory ciliated cells: 10.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (7.11e-3)" "unprognostic (4.08e-2)" "unprognostic (1.83e-1)" "unprognostic (1.89e-3)" "unprognostic (4.87e-2)" "unprognostic (2.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (7.69e-2)" "unprognostic (3.67e-1)" "unprognostic (1.41e-1)" "unprognostic (3.09e-7)" "unprognostic (1.86e-2)" "unprognostic (2.98e-1)" "unprognostic (3.17e-1)" "unprognostic (2.58e-2)" 3.2 2.2 4.0 2.1 2.2 6.1 3.0 4.3 4.7 4.4 0.0 3.8 1.6 2.2 4.5 2.5 3.8 1.6 3.2 3.6 3.3 3.0 4.1 4.1 3.6 2.0 1.1 3.9 2.5 1.8 4.1 1.5 1.4 4.0 2.0 3.9 2.8 1.5 3.8 7.2 4.8 0.5 0.1 5.1 2.9 2.8 3.1 1.1 4.1 0.6 2.1 3.2 3.4 2.8 2.2 5.4 1.3 4.4 0.6 1.4 2.6 0.4 0.0 0.2 0.2 0.6 2.9 3.3 2.1 0.8 0.5 2.5 2.4 1.2 0.7 1.9 1.1 3.5 6.3 2.8 0.2 4.4 2.7 2.0 1.7 1.9 1.1 0.6 0.9 1.4 1.5 4.5 1.0 4.5 2.0 4.3 1.8 0.5 1.3 4.1 0.7 1.8 1.2 3.6 1.5 1.6 0.6 1.6 0.8 1.7 1.3 1.1 2.1 2.5 2.6 2.4 1.3 1.8 2.3 4.1 2.4 2.0 1.3 0.0 0.3 0.0 0.6 0.1 0.3 0.0 0.2 0.2 0.1 0.2 0.3 0.1 0.1 0.4 0.4 0.1 0.0 0.1 4.0 2.2 4.3 4.7 3.6 3.3 2.0 1.1 1.4 0.1 3.1 2.8 0.8 16.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 7.4 1.8 0.0 0.5 0.8 0.0 0.0 0.6 0.0 0.3 0.4 1.7 0.0 0.0 0.0 1.5 0.1 1.3 0.0 0.7 12.6 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.3 10.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.2 0.0 0.0 NPIPB3 "KIAA0220, NPIPL3" ENSG00000169246 "Nuclear pore complex interacting protein family member B3" Q92617 16 21402237-21448567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.8;Gastric mucus-secreting cells: 2.0;Skeletal myocytes: 3.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 161.9" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (2.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "unprognostic (8.01e-2)" "unprognostic (9.97e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-2)" "unprognostic (3.14e-1)" "unprognostic (3.91e-1)" "unprognostic (1.65e-1)" "unprognostic (4.66e-5)" "unprognostic (1.50e-7)" "unprognostic (1.30e-1)" "unprognostic (3.02e-2)" "unprognostic (5.94e-2)" "unprognostic (9.00e-4)" 53.3 47.1 141.3 37.2 137.3 149.4 47.7 127.7 184.3 71.8 111.9 72.4 28.5 38.3 51.8 44.4 58.6 28.5 60.8 118.8 134.1 71.1 65.1 66.3 77.0 133.3 147.3 49.6 47.2 13.1 70.5 21.9 127.9 74.9 34.9 51.7 43.5 22.6 87.9 140.9 76.7 28.1 90.1 99.7 51.3 46.6 134.8 53.6 75.6 24.1 34.8 48.0 52.5 122.8 37.9 37.2 24.5 40.1 30.0 18.1 73.5 25.7 9.6 13.3 14.1 57.5 44.0 56.4 24.1 38.9 17.7 47.0 13.6 41.4 12.5 30.8 20.6 26.6 58.7 161.9 25.6 48.8 46.0 8.8 16.8 35.3 44.3 20.4 19.4 52.5 49.7 77.3 20.4 69.7 51.8 114.0 41.0 22.5 42.5 75.7 25.4 35.0 28.8 23.2 27.8 21.1 15.7 32.5 25.9 47.2 35.7 20.7 29.5 62.9 36.4 6.4 40.4 37.8 30.8 49.2 25.0 38.3 34.9 3.5 2.3 1.5 2.6 1.4 1.2 2.2 1.5 1.6 1.2 2.4 2.0 1.3 2.1 2.0 1.1 4.8 0.9 0.1 141.3 137.3 127.7 184.3 118.8 134.1 133.3 147.3 127.9 90.1 134.8 122.8 0.1 0.0 0.0 1.6 0.5 2.8 0.4 0.2 0.6 0.0 0.1 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 1.7 0.0 0.0 1.0 2.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.3 0.6 0.0 0.0 0.2 1.8 1.9 0.0 0.0 1.0 1.5 1.3 0.0 0.0 0.0 0.7 0.8 0.0 0.0 1.7 0.0 0.0 3.1 0.8 0.0 0.0 1.3 1.7 0.0 0.8 0.2 0.0 0.2 NPIPB4 ENSG00000185864 "Nuclear pore complex interacting protein family member B4" C9JG80 16 21834569-21880827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Astrocytes: 149.5;Early spermatids: 150.6;Excitatory neurons: 255.3;Inhibitory neurons: 182.5;Microglial cells: 391.6;Oligodendrocyte precursor cells: 207.6;Oligodendrocytes: 217.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (3.09e-3)" "unprognostic (3.51e-3)" "unprognostic (4.01e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.82e-2)" "unprognostic (3.66e-1)" "unprognostic (1.76e-1)" "unprognostic (4.05e-3)" "unprognostic (6.04e-8)" "unprognostic (3.37e-1)" "unprognostic (7.78e-2)" "unprognostic (2.32e-1)" "unprognostic (5.46e-3)" 25.3 18.6 29.4 26.3 11.2 88.8 24.9 45.3 24.1 28.1 0.0 27.0 17.3 20.5 71.0 19.4 27.8 17.6 21.3 12.1 5.1 25.0 30.4 27.6 38.8 8.3 4.6 24.4 22.4 6.6 23.6 14.8 8.9 28.8 27.8 31.2 23.3 11.8 28.5 104.5 36.7 13.0 0.0 41.1 26.5 20.8 14.8 17.3 31.9 7.5 27.1 20.6 24.8 9.0 14.0 18.6 17.3 13.7 12.2 17.3 29.3 16.7 5.1 5.5 8.9 38.6 19.2 27.2 12.4 14.5 5.1 15.5 9.4 14.0 10.9 10.9 8.7 10.5 56.2 53.0 8.0 44.2 26.9 13.0 16.8 14.6 24.3 11.3 12.1 21.2 23.3 22.8 8.4 40.0 16.9 27.7 20.8 4.5 9.9 25.4 10.3 15.3 6.2 13.6 17.2 10.5 11.1 12.8 8.2 16.3 16.9 12.9 26.9 29.1 14.7 14.0 14.7 11.6 11.9 27.8 9.2 20.4 14.0 3.1 0.9 0.3 0.7 0.5 0.6 1.0 1.0 0.5 0.2 2.7 0.8 0.9 1.4 2.2 0.6 2.0 0.2 0.2 29.4 11.2 45.3 24.1 12.1 5.1 8.3 4.6 8.9 0.0 14.8 9.0 7.1 3.2 16.8 149.5 4.3 7.6 1.2 0.9 3.4 5.1 1.3 0.9 2.1 0.0 6.1 0.0 4.2 0.5 7.6 1.7 0.0 1.0 150.6 5.1 5.4 3.6 1.2 4.4 255.3 0.6 0.3 3.6 6.1 8.8 10.8 3.0 1.4 0.8 0.7 1.7 182.5 2.1 2.0 1.2 5.2 25.3 0.3 4.3 0.0 391.6 2.8 1.2 3.1 207.6 217.1 1.4 3.0 0.4 5.9 0.7 1.0 0.1 3.9 6.4 0.0 3.1 3.1 1.5 0.5 2.3 8.4 0.8 7.0 1.8 2.2 0.7 NPIPB5 ENSG00000243716 "Nuclear pore complex interacting protein family member B5" A8MRT5 16 22479121-22536521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 57.1;Club cells: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (7.52e-4)" "unprognostic (2.08e-1)" "unprognostic (2.32e-2)" "unprognostic (9.43e-3)" "unprognostic (3.96e-1)" "unprognostic (2.64e-3)" "unprognostic (2.40e-3)" "unprognostic (4.20e-2)" "unprognostic (1.65e-1)" "unprognostic (4.19e-2)" "unprognostic (1.09e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-10)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (3.86e-2)" "unprognostic (3.76e-5)" 58.6 36.5 63.2 66.8 37.2 136.4 58.0 69.0 90.4 67.1 6.8 61.8 36.5 41.8 124.9 41.2 54.9 27.7 50.9 24.8 27.4 49.0 38.4 77.0 82.6 22.1 37.3 57.1 49.4 14.7 50.4 29.3 22.9 58.9 47.3 115.7 56.7 22.8 78.4 212.1 90.9 25.3 2.6 84.6 50.9 41.0 57.1 43.1 75.5 17.7 61.0 45.9 58.8 33.2 31.3 25.7 16.3 23.3 27.8 24.9 35.4 18.9 6.3 11.5 13.9 35.4 53.3 43.9 34.7 17.4 11.3 24.5 41.2 21.3 19.0 53.8 17.2 16.1 85.6 66.1 27.5 83.5 29.1 30.1 20.9 23.0 41.1 20.6 18.3 45.0 43.5 52.8 10.3 57.6 26.6 101.3 46.4 4.9 11.7 44.7 12.1 51.1 18.2 18.9 21.0 14.9 23.3 36.6 19.7 32.9 19.9 30.8 71.4 39.4 17.4 31.2 30.6 35.7 18.9 54.4 15.7 63.6 14.3 6.2 2.7 2.1 3.9 1.2 1.6 6.8 3.8 2.6 1.4 7.7 4.0 3.5 6.0 2.8 2.5 5.2 2.0 1.3 63.2 37.2 69.0 90.4 24.8 27.4 22.1 37.3 22.9 2.6 57.1 33.2 30.0 28.9 57.1 1.0 20.3 14.4 11.2 3.0 17.1 16.5 10.5 7.1 34.8 4.3 50.6 5.5 10.4 5.1 22.8 3.3 0.0 3.8 7.1 19.3 20.5 23.6 1.2 17.2 0.3 1.4 2.8 20.4 22.4 32.7 10.1 21.0 8.2 2.0 4.4 6.7 0.2 3.8 0.0 8.1 16.7 2.8 10.2 25.5 5.4 1.0 14.2 5.5 12.3 0.5 0.3 5.0 4.0 6.4 21.7 13.0 4.3 1.6 31.6 23.8 0.0 32.7 22.7 3.6 2.3 14.0 11.5 5.9 29.7 9.3 3.3 10.3 NPIPB6 ENSG00000198156 "Nuclear pore complex interacting protein family member B6" E9PJ23 16 28342555-28363508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 39.7" "Group enriched" "Detected in some" 19 "Early spermatids: 300.0;Late spermatids: 151.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.1;hTCEpi: 3.0;NB-4: 3.1;RPMI-8226: 3.4" "HPA011188, HPA053611" Approved Approved Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (7.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.86e-2)" "unprognostic (2.43e-1)" "unprognostic (3.21e-1)" "unprognostic (1.02e-1)" "unprognostic (1.54e-1)" "unprognostic (1.31e-1)" "unprognostic (2.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.79e-4)" "unprognostic (3.20e-1)" "unprognostic (8.36e-2)" "unprognostic (4.78e-1)" "unprognostic (1.04e-3)" 1.2 0.6 4.9 0.3 5.0 0.7 1.3 5.2 8.7 2.5 4.2 2.1 0.3 1.3 1.0 0.9 2.9 0.2 0.9 4.8 5.2 1.1 1.2 1.4 0.5 4.7 4.5 3.2 1.5 0.2 2.5 0.2 5.2 2.3 0.6 1.3 1.1 0.6 1.4 2.1 2.1 0.4 4.3 1.9 1.2 39.7 4.8 0.4 2.4 0.1 0.3 1.5 1.7 6.2 0.1 3.1 1.4 0.3 0.7 0.0 2.7 0.2 0.3 0.0 0.2 0.1 1.3 1.1 0.2 0.1 0.3 0.4 0.3 0.3 0.1 0.7 0.2 0.8 0.7 0.0 0.0 1.0 0.2 0.4 3.0 0.2 0.6 0.5 0.0 1.7 0.1 2.4 0.0 0.7 0.3 3.1 0.7 0.3 0.1 1.6 1.1 3.4 0.0 0.0 0.4 0.6 0.1 0.1 0.3 1.5 0.6 0.3 0.2 0.4 1.0 0.2 0.2 1.0 1.1 0.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 5.0 5.2 8.7 4.8 5.2 4.7 4.5 5.2 4.3 4.8 6.2 0.2 0.0 1.1 0.0 0.1 0.5 0.4 0.0 0.0 0.5 1.6 1.7 0.5 0.0 0.8 0.0 0.0 0.5 0.1 0.4 0.0 0.0 300.0 0.7 0.4 0.3 0.0 0.0 0.0 0.2 0.2 0.4 0.0 1.5 0.0 1.4 1.1 0.2 0.2 0.0 0.0 0.1 0.0 0.3 0.3 151.0 1.2 0.6 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 1.4 1.9 0.0 0.6 0.3 0.2 6.0 0.2 0.0 1.7 0.4 11.7 3.1 0.0 1.3 1.4 0.4 0.3 0.5 0.7 NPSR1 "GPR154, GPRA, PGR14" ENSG00000187258 "Neuropeptide S receptor 1" Q6W5P4 7 34658218-34878332 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.1;Early spermatids: 4.4;Excitatory neurons: 3.8;Inhibitory neurons: 2.2;Late spermatids: 2.1;Oligodendrocyte precursor cells: 1.0" "Group enriched" "Detected in some" 5 "colorectal cancer: 2.3;pancreatic cancer: 2.0;stomach cancer: 2.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 6.2" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.56e-1)" "unprognostic (9.34e-2)" "unprognostic (7.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.00e-2)" "unprognostic (9.35e-2)" "unprognostic (6.34e-3)" "unprognostic (2.85e-1)" "unprognostic (1.36e-2)" "unprognostic (2.08e-2)" 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.2 0.4 1.6 0.6 1.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 32.8;Excitatory neurons: 39.8;Hepatic stellate cells: 160.6;Sertoli cells: 46.0;Smooth muscle cells: 34.1" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HEL: 128.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 30.5 31.0 10.4 2.9 13.1 0.0 32.4 0.0 13.7 7.8 0.0 5.8 1.0 7.3 10.2 1.8 8.4 4.5 4.8 9.1 19.7 32.3 14.7 2.1 17.3 0.3 0.8 2.8 28.7 3.6 3.0 5.2 0.4 2.5 4.5 4.4 21.4 8.3 2.9 9.8 1.5 5.7 5.7 119.6 1.8 4.1 2.2 1.1 7.9 2.6 0.9 1.8 4.9 9.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 7.0 0.0 0.0 0.0 0.0 128.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 1.2 0.0 4.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.0 0.0 0.0 0.1 1.2 0.0 0.6 0.1 0.0 0.0 1.4 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 10.4 13.1 0.0 13.7 9.1 19.7 0.3 0.8 0.4 5.7 2.2 9.0 2.1 0.0 0.5 1.3 0.7 2.8 0.7 0.0 3.4 11.6 19.2 3.3 0.9 1.5 0.0 0.0 2.1 0.0 0.0 3.4 13.7 12.5 5.0 0.0 0.4 10.8 32.8 0.0 39.8 0.0 0.0 5.1 0.0 0.1 0.0 3.7 160.6 0.9 0.1 0.0 18.8 1.6 0.0 7.2 0.9 2.4 11.5 0.1 5.4 4.7 0.0 1.1 0.0 2.0 1.4 0.1 15.9 0.4 0.0 0.5 0.1 0.1 0.0 2.1 46.0 1.1 34.1 0.5 0.6 0.1 1.7 0.0 0.6 0.5 2.1 0.3 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NRSN1 "p24, VMP" ENSG00000152954 "Neurensin 1" Q8IZ57 6 24126186-24154900 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 542.9;choroid plexus: 474.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 139.1;Horizontal cells: 121.1;Inhibitory neurons: 111.9;Oligodendrocyte precursor cells: 69.9" "Cancer enriched" "Detected in single" 17 "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 11.2;SH-SY5Y: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019681, HPA061006" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA019681: , HPA061006: AB_2684413" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (8.00e-3)" "unprognostic (8.01e-3)" "unprognostic (1.70e-1)" "unprognostic (4.53e-3)" "unprognostic (7.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.40e-3)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" 0.0 4.9 276.8 0.4 315.2 0.2 0.0 108.9 281.1 0.1 474.7 1.2 0.4 0.2 0.0 0.1 0.0 0.2 0.0 138.2 466.8 0.1 0.0 0.0 0.1 263.2 332.8 0.0 1.2 0.0 23.5 0.0 468.0 0.0 0.4 22.6 0.1 0.0 0.7 0.1 0.3 0.3 194.7 0.1 0.4 0.3 459.9 0.0 0.1 0.0 0.1 0.0 0.1 542.9 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 11.2 9.2 0.0 0.0 0.2 0.1 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.3 0.5 0.2 0.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 276.8 315.2 108.9 281.1 138.2 466.8 263.2 332.8 468.0 194.7 459.9 542.9 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.1 0.0 0.0 139.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 121.1 111.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 23.7 0.0 69.9 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NRSN2 "C20orf98, dJ1103G7.6" ENSG00000125841 "Neurensin 2" Q9GZP1 20 346782-359660 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 154.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015967 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Nucleoplasm, Cytosol" "HPA015967: AB_1854647" "unprognostic (5.67e-2)" "unprognostic (3.47e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (4.05e-2)" "unprognostic (4.48e-2)" "unprognostic (1.48e-1)" "unprognostic (4.96e-2)" "unprognostic (5.92e-2)" "prognostic favorable (1.61e-4)" "unprognostic (6.96e-2)" "unprognostic (1.96e-3)" "unprognostic (2.94e-2)" "unprognostic (1.96e-1)" "unprognostic (7.85e-3)" "unprognostic (1.73e-3)" 19.9 57.0 105.7 10.5 114.4 1.7 17.4 87.8 154.7 30.1 71.3 28.3 6.0 32.5 25.9 9.7 27.9 15.4 30.9 114.3 100.6 33.0 4.8 22.4 7.5 94.4 92.0 36.0 20.3 42.6 60.4 16.9 93.9 28.3 9.7 56.9 21.1 25.5 3.4 11.4 13.1 27.5 80.5 16.8 20.2 30.6 96.6 5.5 28.1 5.7 7.2 23.5 18.2 102.9 56.5 68.3 40.2 37.7 53.0 58.4 15.2 37.4 72.3 66.3 66.8 38.2 1.2 0.0 12.6 70.7 48.9 24.1 33.5 5.8 42.4 0.3 33.0 20.8 32.5 70.7 53.5 0.6 3.3 67.4 4.5 48.2 8.1 54.1 46.4 0.3 40.3 35.1 59.2 10.0 0.9 17.9 31.3 0.7 34.9 32.4 22.1 2.7 67.4 0.3 80.8 58.0 44.9 13.0 64.9 26.5 53.2 19.7 31.0 70.6 36.4 2.6 45.6 6.5 1.4 14.7 9.5 0.6 36.7 0.0 0.7 1.2 2.4 0.3 0.7 5.6 0.8 2.6 1.5 6.9 1.0 1.8 0.0 2.8 0.3 3.5 0.6 1.1 105.7 114.4 87.8 154.7 114.3 100.6 94.4 92.0 93.9 80.5 96.6 102.9 3.8 0.0 3.1 16.0 2.2 3.2 3.6 8.5 7.4 26.5 5.8 5.0 5.5 1.5 6.1 12.9 2.1 7.3 0.5 2.6 1.9 14.7 9.6 4.7 12.0 6.9 29.4 1.3 21.0 1.6 6.8 10.4 3.1 3.9 5.1 7.6 5.7 0.3 3.2 16.8 27.1 2.6 4.1 0.9 2.2 14.4 13.1 0.7 3.6 2.8 2.1 17.3 2.1 12.1 5.9 2.9 1.8 10.5 2.6 3.3 0.2 7.8 3.6 15.4 19.7 4.9 9.2 21.3 12.8 1.4 2.3 4.4 1.4 12.9 2.2 2.9 NUP210L ENSG00000143552 "Nucleoporin 210 like" Q5VU65 1 153992685-154155116 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 26.6" "Cell type enhanced" "Detected in some" "Early spermatids: 20.3;Inhibitory neurons: 8.4;Late spermatids: 8.5;Oligodendrocytes: 19.2;Spermatocytes: 28.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 47 "MCF7: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047195, HPA064245, HPA066707" Enhanced Approved "Nuclear bodies" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" "HPA047195: AB_2679980, HPA064245: AB_2685224, HPA066707: AB_2685706" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (3.01e-1)" "unprognostic (1.80e-2)" "unprognostic (1.63e-2)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.79e-3)" "unprognostic (3.45e-2)" "unprognostic (5.57e-2)" "unprognostic (4.51e-4)" "unprognostic (1.15e-1)" "unprognostic (9.35e-10)" "unprognostic (4.20e-2)" "unprognostic (3.78e-2)" "unprognostic (7.45e-2)" "unprognostic (4.09e-2)" 0.1 0.0 0.2 0.0 0.7 0.1 0.0 2.4 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.7 0.6 0.1 0.1 0.0 0.3 0.0 0.8 0.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 26.6 0.5 0.0 0.2 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.7 2.4 0.9 0.4 0.3 0.7 0.6 0.8 0.3 0.5 2.3 0.6 0.0 0.0 6.2 0.5 0.3 0.1 0.1 0.0 0.0 0.3 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 20.3 0.7 0.6 0.9 0.0 0.4 7.0 0.2 0.1 0.5 0.0 1.5 0.0 0.1 0.0 0.0 0.2 0.0 8.4 0.1 0.0 0.0 0.6 8.5 0.9 0.8 0.0 2.8 0.0 0.0 0.0 4.5 19.2 0.0 0.0 1.2 1.7 0.1 0.0 0.1 0.1 0.0 6.6 1.8 0.3 28.2 5.1 0.3 0.6 0.0 0.4 0.1 0.1 0.3 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 ODF4 "CT136, OPPO1" ENSG00000184650 "Outer dense fiber of sperm tails 4" Q2M2E3 17 8339840-8346048 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 131 "testis: 13.0" "Group enriched" "Detected in some" 48 "Early spermatids: 32.1;Late spermatids: 36.0;Spermatocytes: 47.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA072129 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA072129: " "unprognostic (5.16e-2)" "unprognostic (5.13e-1)" "unprognostic (3.54e-4)" "unprognostic (3.64e-1)" "unprognostic (5.40e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 36.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ODR4 "C1orf27, FLJ20505, odr-4, TTG1" ENSG00000157181 "Odr-4 GPCR localization factor homolog" Q5SWX8 1 186375838-186421378 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 37.8;Glandular and luminal cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015988, HPA031352" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane" "HPA015988: AB_1845644, HPA031352: AB_2673838" "unprognostic (1.19e-2)" "unprognostic (4.23e-2)" "unprognostic (1.12e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" "unprognostic (8.57e-2)" "unprognostic (8.11e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.15e-2)" "unprognostic (9.85e-2)" "unprognostic (2.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (4.20e-2)" 11.9 14.4 7.5 7.2 9.2 15.0 14.0 10.4 10.1 13.3 8.4 10.8 13.4 9.4 17.2 7.8 8.8 10.6 10.0 7.6 8.2 16.7 21.8 9.5 6.7 8.9 8.6 10.3 29.1 32.4 12.4 14.2 9.2 16.6 12.7 15.2 21.7 12.2 9.0 10.3 13.6 8.8 8.7 8.5 13.1 8.3 8.2 6.4 19.9 9.5 7.1 11.5 8.2 11.9 12.6 13.9 15.1 12.1 17.5 16.3 28.8 19.9 12.2 12.7 12.8 28.2 29.7 8.7 23.5 9.9 11.6 32.3 11.4 10.9 12.5 7.1 10.9 8.2 17.7 15.9 16.4 13.8 9.6 12.5 21.3 15.4 24.1 13.2 13.8 9.0 32.1 17.3 15.3 13.5 9.7 14.3 21.6 46.0 5.0 11.2 10.5 25.0 26.1 12.9 11.0 17.2 15.1 33.0 24.5 26.9 29.1 12.4 13.2 18.1 11.5 12.2 18.9 20.2 13.3 13.3 9.8 7.4 16.7 1.4 9.0 2.5 3.0 8.9 4.5 3.6 3.8 4.2 7.6 2.3 4.7 3.6 3.9 10.0 11.4 4.8 5.7 3.9 7.5 9.2 10.4 10.1 7.6 8.2 8.9 8.6 9.2 8.7 8.2 11.9 28.1 28.9 37.8 0.0 4.2 0.0 0.0 0.0 0.0 0.0 18.8 16.5 0.0 0.0 29.7 25.8 0.0 22.0 12.6 0.0 9.8 22.8 0.0 26.8 27.0 9.8 0.0 0.0 0.0 25.4 25.7 12.3 0.0 38.6 12.6 26.4 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 6.7 0.0 0.0 0.0 0.0 24.7 0.0 0.0 4.0 0.0 0.0 10.7 15.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 28.0 6.9 29.0 0.0 0.0 OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "HPA055120: AB_2682702" "prognostic favorable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favorable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" 11.4 18.7 15.1 14.0 22.8 12.8 19.7 23.1 14.9 16.7 14.9 20.8 14.9 13.5 17.8 13.3 19.4 15.1 19.8 13.0 19.5 28.4 31.1 11.9 23.4 18.8 17.9 13.5 17.9 18.1 10.4 11.5 21.1 20.8 20.0 20.5 19.5 16.7 28.2 12.8 14.2 12.4 15.6 20.2 17.3 8.2 18.3 20.2 20.1 29.9 21.5 14.8 10.5 27.3 31.2 13.0 8.3 7.9 41.7 39.0 24.6 12.7 13.9 10.9 13.7 4.0 18.7 69.8 26.3 13.1 37.8 31.2 31.1 31.3 13.3 55.1 17.9 22.0 10.4 16.1 20.3 54.3 14.7 37.3 33.6 10.4 22.4 24.1 9.3 34.3 42.7 20.1 29.2 19.5 18.0 19.4 12.4 47.4 28.5 22.1 27.7 29.1 23.6 20.5 8.7 4.3 26.0 41.9 37.6 38.4 19.5 20.1 5.4 5.6 10.8 27.8 13.5 16.3 23.4 46.2 16.8 42.2 14.1 20.1 14.4 32.1 19.4 24.1 25.6 35.6 23.7 23.1 15.4 35.0 33.9 31.5 17.2 30.9 35.1 8.2 23.6 15.9 15.1 22.8 23.1 14.9 13.0 19.5 18.8 17.9 21.1 15.6 18.3 27.3 8.4 19.2 11.5 37.9 25.7 6.0 18.2 35.6 13.6 7.8 15.0 12.3 27.2 8.6 33.0 25.8 12.5 22.9 14.4 8.4 25.4 11.2 5.8 31.6 10.8 6.3 6.0 15.6 18.3 5.5 10.0 12.0 5.6 18.4 6.3 10.9 6.4 18.7 15.8 1.7 31.7 17.7 36.7 10.1 9.7 12.7 9.9 12.9 7.2 29.0 11.3 10.9 15.5 52.8 106.5 3.8 10.9 8.6 16.8 12.3 8.5 32.4 63.1 20.5 6.6 12.0 8.6 14.3 13.6 17.3 6.8 18.3 20.7 17.1 14.6 17.1 OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527427-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA044881: AB_10964052" "unprognostic (3.37e-1)" "unprognostic (3.89e-2)" "unprognostic (2.66e-1)" "unprognostic (5.71e-3)" "unprognostic (1.24e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (3.14e-3)" "unprognostic (4.53e-2)" "unprognostic (8.06e-3)" "unprognostic (1.72e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.30e-12)" "unprognostic (5.85e-2)" "unprognostic (1.94e-1)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" 4.8 7.2 3.3 4.7 3.4 4.0 3.5 4.4 5.2 3.0 3.7 4.6 4.0 4.9 3.0 5.8 3.4 3.3 10.5 3.2 3.1 7.4 7.8 4.4 4.7 4.9 4.0 3.4 4.4 12.0 6.0 4.4 5.0 3.8 3.9 6.4 4.0 4.1 11.1 5.8 5.0 4.7 2.5 5.8 4.9 8.9 5.5 4.6 4.6 12.9 4.7 4.1 3.5 3.2 15.2 18.9 7.4 7.3 4.8 5.9 11.3 9.7 8.9 10.1 10.7 8.8 10.5 13.0 6.9 9.8 11.5 12.0 12.5 13.3 8.9 24.0 12.6 20.1 10.8 9.1 8.8 14.1 25.0 8.9 10.1 11.2 12.2 5.8 7.3 7.6 17.5 14.2 6.9 9.3 11.3 5.8 6.5 12.6 12.9 10.9 6.7 7.1 8.0 26.9 5.5 6.6 12.4 11.3 5.2 6.6 6.3 8.0 15.9 8.5 9.7 7.1 16.7 9.5 19.1 10.6 8.2 10.1 13.1 5.6 5.3 2.9 3.6 7.8 3.6 4.4 3.2 3.1 5.6 3.9 3.9 4.0 4.7 7.8 10.5 5.1 4.8 3.6 3.3 3.4 4.4 5.2 3.2 3.1 4.9 4.0 5.0 2.5 5.5 3.2 11.0 12.8 11.7 8.5 23.0 18.7 22.4 14.6 13.1 22.8 9.2 7.9 25.4 17.2 11.6 11.0 52.1 25.6 15.7 18.8 25.4 18.4 18.5 12.8 13.8 15.2 13.8 5.7 9.5 21.1 29.8 10.6 14.3 20.1 15.9 8.9 11.4 21.9 16.3 20.2 10.2 14.5 16.2 11.4 28.3 20.2 6.2 17.4 14.2 4.7 19.0 15.1 11.3 3.0 8.1 18.2 19.2 6.4 11.9 15.8 21.2 16.8 10.7 36.0 0.0 23.3 23.6 23.9 13.1 11.2 19.6 36.3 14.4 19.5 16.6 16.7 OPN1LW "CBBM, CBP, COD5, RCP" ENSG00000102076 "Opsin 1, long wave sensitive" P04000 X 154144243-154159032 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2568 "retina: 256.7" "Cell type enriched" "Detected in some" 20 "Cone photoreceptor cells: 725.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (6.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 256.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 725.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPN1MW "CBBM, CBD, COD5, GCP, OPN1MW1" ENSG00000268221 "Opsin 1, medium wave sensitive" P04001 X 154182596-154196861 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 133 "retina: 13.3" "Cell type enriched" "Detected in single" 111 "Cone photoreceptor cells: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OPN1MW2 ENSG00000166160 "Opsin 1, medium wave sensitive 2" P0DN77 X 154219756-154233286 "Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 458 "retina: 45.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR51E2 PSGR ENSG00000167332 "Olfactory receptor family 51 subfamily E member 2" Q9H255 11 4680171-4697854 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 9.6;prostate: 28.9" "Cell type enriched" "Detected in some" 6 "Enteroendocrine cells: 77.4" "Cancer enriched" "Detected in some" 274 "prostate cancer: 217.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;BJ hTERT+: 1.1;hTERT-RPE1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.98e-3)" "unprognostic (1.91e-1)" "unprognostic (6.09e-3)" "unprognostic (1.57e-2)" "unprognostic (8.00e-4)" "unprognostic (3.61e-2)" "unprognostic (6.27e-2)" "unprognostic (1.66e-1)" "unprognostic (3.05e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-1)" "unprognostic (3.61e-1)" "unprognostic (5.04e-5)" "unprognostic (3.34e-2)" "unprognostic (4.66e-2)" "unprognostic (5.76e-2)" "unprognostic (3.29e-1)" 0.6 0.2 0.3 1.0 0.4 0.1 0.5 0.4 0.5 0.7 0.6 9.6 0.2 1.3 0.3 0.0 0.5 0.3 0.2 0.4 0.2 0.4 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.0 0.0 4.0 0.4 28.9 2.2 0.1 0.0 2.3 0.4 0.2 0.8 2.1 0.1 0.0 0.4 0.3 0.5 0.0 0.1 0.4 0.0 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.5 0.4 0.2 0.3 0.3 0.4 0.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 77.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.3;Hofbauer cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 94.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" 17.3 34.1 18.0 8.2 16.5 17.6 15.2 16.9 17.1 24.4 26.0 22.7 9.2 18.3 16.3 15.4 19.2 9.9 16.7 15.3 16.3 19.3 70.2 14.2 11.9 18.6 18.5 18.9 17.7 18.9 18.0 14.9 17.1 26.3 8.6 4.0 14.6 17.0 7.9 14.3 16.1 9.8 17.4 22.5 17.1 15.6 20.5 11.2 16.4 8.1 10.6 27.2 20.2 17.7 2.8 15.8 8.1 10.7 68.1 60.7 0.6 9.3 62.3 6.8 17.2 1.5 26.1 3.9 20.7 17.9 27.5 12.7 1.4 17.6 4.6 12.3 5.2 10.2 4.9 16.1 94.9 11.2 30.5 65.5 45.9 13.1 25.5 63.8 11.7 2.2 11.7 20.6 22.1 10.8 0.7 42.6 6.6 9.1 4.3 8.6 6.3 30.8 26.2 6.8 2.0 13.5 8.4 2.6 14.9 19.5 19.7 45.5 8.5 5.1 3.5 11.4 2.2 50.4 4.0 3.1 25.3 26.4 7.9 23.2 8.7 26.6 3.4 9.2 3.6 7.1 1.8 2.7 8.5 6.7 2.2 2.9 15.3 11.7 12.6 9.5 2.7 3.3 18.0 16.5 16.9 17.1 15.3 16.3 18.6 18.5 17.1 17.4 20.5 17.7 12.1 6.4 10.8 0.0 23.9 7.9 24.5 25.6 32.5 1.5 11.1 19.6 6.9 5.7 11.6 16.5 2.1 28.1 25.9 11.1 13.7 21.4 61.1 16.5 21.8 16.5 15.0 16.2 0.0 11.4 2.7 25.9 4.1 10.5 7.0 17.9 23.6 77.3 93.8 35.3 0.0 11.3 10.2 43.7 11.5 36.7 53.1 31.4 21.4 0.0 39.1 24.4 17.5 0.0 0.0 9.5 18.4 43.2 18.1 14.0 9.5 48.2 14.7 3.6 26.3 11.0 14.0 26.5 2.5 17.0 4.5 4.4 9.7 61.0 5.8 20.4 ORMDL1 ENSG00000128699 "ORMDL sphingolipid biosynthesis regulator 1" Q9P0S3 2 189770267-189784364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.45e-1)" "unprognostic (5.34e-3)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-3)" "unprognostic (1.86e-2)" "unprognostic (6.70e-3)" "prognostic favorable (3.04e-5)" "unprognostic (5.90e-3)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.84e-9)" "unprognostic (2.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "prognostic favorable (1.49e-5)" 60.0 66.2 27.0 50.3 28.6 51.7 54.9 34.2 33.2 67.9 36.2 60.7 41.1 56.5 99.5 46.1 55.3 47.4 37.8 28.4 33.1 55.2 68.7 66.9 75.2 27.3 27.7 50.8 84.5 42.3 79.3 63.1 28.2 62.2 50.1 82.0 66.1 47.3 41.5 84.3 84.9 43.9 30.4 131.2 64.0 58.8 28.8 44.2 62.9 23.9 69.4 50.3 51.7 32.8 31.4 20.5 68.0 54.8 88.2 100.4 70.3 64.9 61.7 71.0 71.5 41.9 51.7 57.8 44.7 49.9 36.7 52.1 43.4 42.0 77.5 65.6 55.2 82.3 106.2 61.9 102.6 65.8 63.8 113.1 51.6 61.8 70.6 99.0 58.4 57.9 48.3 85.9 72.9 28.6 58.6 127.0 60.7 32.4 86.4 46.4 50.2 78.7 87.4 49.3 43.6 51.4 33.8 32.0 74.3 78.3 38.7 73.3 61.6 70.1 48.1 44.9 65.7 82.9 66.6 55.4 76.4 68.7 38.6 49.4 32.7 39.8 35.8 39.5 33.7 37.9 39.3 36.5 26.7 35.4 45.0 40.9 13.3 29.4 48.3 46.1 46.1 33.5 27.0 28.6 34.2 33.2 28.4 33.1 27.3 27.7 28.2 30.4 28.8 32.8 80.4 80.1 50.2 41.4 90.9 56.3 55.1 95.6 26.7 138.3 69.8 76.7 34.4 41.5 65.5 36.8 175.2 212.4 141.2 36.0 33.2 58.7 42.8 58.0 63.9 61.8 42.4 38.7 53.6 67.3 73.0 58.1 24.5 47.3 45.6 84.3 47.5 37.4 86.9 65.6 60.1 37.2 101.7 126.8 60.9 18.9 74.3 83.3 39.2 33.7 96.4 107.7 117.4 57.8 49.4 66.5 48.3 48.5 83.5 79.1 62.8 45.9 66.3 217.2 52.6 55.4 63.8 186.8 145.0 32.5 60.7 218.1 104.5 117.4 46.3 51.5 ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" 37.5 38.1 14.6 24.2 17.0 20.4 31.3 18.3 20.5 30.0 24.7 44.5 27.2 28.4 51.3 75.9 26.3 20.6 30.1 14.8 18.4 40.7 47.5 35.5 23.0 19.0 18.0 16.8 32.9 44.5 29.7 22.3 18.5 30.8 48.4 14.8 40.2 23.2 19.7 36.4 30.2 26.4 17.2 33.2 32.9 42.7 18.3 27.6 27.4 11.1 38.5 41.7 36.8 20.2 55.9 103.5 43.1 22.4 81.2 40.4 47.7 66.5 66.0 57.0 49.9 116.6 133.8 34.5 69.3 80.7 58.5 100.3 34.6 138.7 56.6 35.9 51.4 46.7 89.7 65.9 85.8 56.7 47.4 50.9 125.2 99.9 103.3 73.3 81.0 38.2 25.0 91.1 73.7 89.3 34.8 25.3 20.9 87.8 82.0 22.8 34.5 88.4 149.8 159.1 37.4 23.8 84.9 99.9 38.4 64.8 120.0 40.1 59.4 30.5 42.6 36.4 42.7 43.6 39.1 28.1 48.9 22.4 43.1 50.4 73.0 107.1 86.5 92.8 76.8 93.2 82.1 92.1 73.4 76.1 67.8 81.5 91.8 74.1 108.7 119.9 107.8 72.1 14.6 17.0 18.3 20.5 14.8 18.4 19.0 18.0 18.5 17.2 18.3 20.2 43.1 73.7 38.3 1.3 39.8 23.3 71.9 132.9 15.4 9.9 43.1 30.0 3.9 45.8 99.4 53.3 12.5 74.7 49.6 125.7 29.4 133.7 171.0 77.9 25.7 42.0 46.1 26.5 0.7 168.1 117.5 22.0 28.1 86.0 51.9 14.0 35.3 82.2 125.3 8.4 0.8 66.7 69.2 42.5 49.1 68.0 25.4 57.4 56.9 2.8 111.4 24.8 77.2 1.0 4.0 197.4 133.5 23.3 50.8 95.7 89.7 76.0 149.2 18.4 19.7 13.5 32.9 107.0 61.7 50.6 33.4 151.6 44.6 30.5 56.2 91.3 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OXA1L "MGC133129, OXA1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 32: Non-specific - Translation" Mitochondria "HPA003531: AB_1079539" "unprognostic (4.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (7.25e-2)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "prognostic favorable (4.82e-4)" "unprognostic (8.35e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (1.15e-3)" 77.7 90.7 27.6 40.8 28.5 71.9 67.6 31.4 28.8 59.4 47.1 72.9 66.3 55.0 48.1 76.6 55.8 49.6 147.2 27.5 29.6 70.8 108.6 54.8 70.0 31.3 29.1 71.2 98.0 105.3 27.5 38.0 31.1 45.0 57.7 41.9 64.2 44.8 234.9 69.3 58.9 46.1 29.1 62.3 83.9 25.0 31.6 63.6 54.9 272.5 75.5 61.3 60.4 31.1 89.3 121.3 48.8 82.1 146.7 217.4 94.4 64.0 138.1 94.3 107.9 91.1 96.4 167.0 86.4 75.0 73.0 121.0 103.0 126.3 90.0 67.6 65.4 79.1 73.2 329.7 165.5 150.9 88.4 211.0 137.6 75.4 114.9 114.7 273.3 93.8 62.2 124.0 103.4 130.0 91.8 51.3 53.2 118.5 150.0 92.9 87.2 128.3 117.9 103.4 35.1 67.0 94.6 205.7 129.7 58.4 89.2 122.7 86.2 52.7 62.2 98.5 75.4 94.0 84.7 78.1 41.6 83.6 60.0 11.9 68.1 18.5 29.5 71.6 36.0 51.0 42.5 37.4 95.1 54.4 47.4 35.6 15.1 41.7 58.5 26.9 55.8 53.7 27.6 28.5 31.4 28.8 27.5 29.6 31.3 29.1 31.1 29.1 31.6 31.1 30.6 48.1 44.0 7.8 83.7 69.5 61.1 89.0 92.8 31.0 52.1 46.5 118.0 72.9 62.1 29.5 10.4 72.8 32.5 48.9 74.3 85.2 10.2 20.4 40.3 58.6 40.7 64.3 6.8 161.3 113.0 47.6 66.8 23.1 80.4 56.5 64.2 102.9 143.4 18.5 7.5 75.3 38.7 148.1 76.8 13.3 57.2 85.6 51.6 3.7 133.4 22.9 74.2 4.5 8.0 86.3 69.7 36.9 84.2 45.6 101.4 116.0 42.6 38.3 39.5 39.4 43.0 31.8 28.4 112.9 67.3 57.2 57.9 70.6 112.1 74.9 P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.0;pancreas: 65.1;urinary bladder: 75.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 185.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.3" "Group enriched" "Detected in many" 30 "dendritic cells: 15.1;granulocytes: 23.5;monocytes: 46.3" "Cell line enhanced" "Detected in some" "HEL: 13.8;HMC-1: 8.4;Karpas-707: 16.8;THP-1: 14.7;U-937: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.3" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" 9.8 2.0 0.5 4.4 0.8 42.0 1.5 0.8 0.7 7.7 0.4 13.4 9.3 7.3 1.8 23.0 3.9 2.0 2.0 0.5 0.7 1.0 0.7 4.8 2.9 0.8 0.9 2.1 65.1 0.1 0.3 3.8 0.8 10.7 9.2 0.1 1.6 34.1 0.5 5.9 9.0 6.0 0.7 13.0 2.8 2.6 0.6 2.0 0.4 0.3 3.2 75.5 8.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.2 0.1 1.1 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.1 3.3 0.0 0.4 0.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 7.4 0.0 0.0 10.8 11.9 0.0 20.4 0.0 0.4 0.0 0.0 5.9 0.9 0.0 0.0 23.5 0.0 46.3 15.1 0.0 8.2 0.5 0.8 0.8 0.7 0.5 0.7 0.8 0.9 0.8 0.7 0.6 1.0 0.1 3.2 4.2 0.7 15.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.1 8.9 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 18.5 0.3 2.0 0.1 0.9 0.5 0.0 185.4 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.0 5.1 2.4 0.2 0.0 22.5 0.0 1.0 7.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 36.0 0.0 0.0 0.1 0.7 0.0 0.0 0.4 3.4 0.0 0.1 0.1 0.9 0.0 1.8 0.5 0.3 0.0 P2RX2 "DFNA41, P2X2" ENSG00000187848 "Purinergic receptor P2X 2" Q9UBL9 12 132618776-132622388 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;epididymis: 21.8;prostate: 14.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.6;Endometrial ciliated cells: 2.6;Fibroblasts: 8.3;Gastric mucus-secreting cells: 1.1;Peritubular cells: 3.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Group enriched" "Detected in many" 7 "amygdala: 9.2;cerebral cortex: 11.3;hippocampal formation: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 5.1;T-47d: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.12e-1)" "unprognostic (1.49e-2)" "unprognostic (5.92e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (3.12e-1)" "unprognostic (5.79e-3)" "unprognostic (6.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.11e-2)" "unprognostic (3.66e-2)" "unprognostic (1.88e-2)" "unprognostic (6.21e-2)" "unprognostic (3.05e-1)" "unprognostic (9.12e-2)" 1.1 0.1 9.2 0.6 0.4 0.1 0.2 0.3 11.3 0.7 0.0 2.4 1.1 0.2 21.8 7.2 9.3 0.1 0.0 10.1 1.5 2.5 0.4 4.9 1.9 0.1 0.2 0.3 0.5 0.7 1.3 0.4 0.1 14.1 0.3 0.0 0.1 9.0 0.0 0.2 4.3 0.1 0.0 3.2 1.7 1.5 1.0 0.4 0.2 0.0 0.8 1.0 1.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 5.1 0.1 0.3 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.9 0.0 0.6 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.4 0.3 11.3 10.1 1.5 0.1 0.2 0.1 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.1 0.0 0.0 0.1 0.0 0.1 8.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 P2RX3 P2X3 ENSG00000109991 "Purinergic receptor P2X 3" P56373 11 57338352-57372396 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.9;liver: 1.7;testis: 5.2" "Group enriched" "Detected in some" 28 "Early spermatids: 34.5;Late spermatids: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057776 Uncertain NA NA "Cluster 43: Testis - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057776: AB_2683526" "unprognostic (5.44e-2)" "unprognostic (9.43e-2)" "unprognostic (2.84e-1)" "unprognostic (1.33e-3)" "unprognostic (2.24e-2)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-7)" "unprognostic (1.58e-1)" "unprognostic (2.88e-1)" "unprognostic (3.00e-2)" "unprognostic (1.29e-1)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.5 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121209861-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.3;Distal enterocytes: 133.7;Hofbauer cells: 129.5;Syncytiotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA039494: AB_10969132" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" "unprognostic (5.43e-2)" "prognostic favorable (6.30e-10)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (7.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.13e-1)" "unprognostic (6.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.76e-3)" 10.1 9.9 4.8 15.1 5.0 14.1 12.7 8.3 5.6 18.8 4.6 33.5 28.9 8.5 3.7 5.0 15.3 16.8 7.2 5.1 5.3 13.0 11.5 20.4 15.9 6.7 5.4 18.1 37.4 33.1 5.1 32.7 6.0 12.1 30.2 2.0 30.1 12.0 1.0 4.5 32.8 10.7 6.3 12.6 20.2 6.0 6.3 7.8 12.9 2.3 8.9 12.1 4.1 7.6 6.6 15.4 1.1 21.7 10.3 8.3 40.6 4.9 26.1 6.7 13.3 10.9 23.1 6.4 18.5 17.4 48.2 2.3 4.7 3.2 4.1 17.5 11.8 3.1 0.9 12.5 25.3 7.6 42.5 11.9 6.8 11.0 14.5 20.4 24.2 7.7 6.1 16.2 5.0 31.8 4.7 10.7 5.5 31.8 10.5 6.6 29.5 34.6 3.1 18.0 6.1 9.0 16.0 8.8 55.0 5.7 38.5 21.2 2.1 10.0 11.2 1.2 5.2 28.0 26.1 3.7 19.6 10.2 9.1 72.3 59.1 10.7 13.6 63.1 15.1 11.3 21.9 13.3 32.5 7.1 16.4 9.6 0.8 29.6 54.6 4.4 17.1 32.6 4.8 5.0 8.3 5.6 5.1 5.3 6.7 5.4 6.0 6.3 6.3 7.6 8.4 6.4 19.2 6.5 14.0 3.8 8.9 11.9 6.8 11.1 17.7 11.9 3.8 21.5 11.2 20.2 2.1 135.3 13.7 133.7 0.0 69.7 15.2 9.8 8.9 9.2 21.5 2.1 6.4 35.4 73.8 14.3 19.4 15.1 13.9 14.3 23.6 9.4 129.5 15.2 5.3 90.3 20.3 43.7 20.8 25.1 8.7 53.7 10.6 18.7 57.9 6.5 19.6 4.5 8.0 33.1 80.6 9.8 21.9 10.2 98.7 23.2 6.4 8.6 19.7 7.4 12.0 8.1 6.6 3.4 4.0 155.7 17.8 15.4 24.7 9.7 P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.6;Excitatory neurons: 8.9;Inhibitory neurons: 7.9;Ionocytes: 8.2;Skeletal myocytes: 20.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;LHCN-M2: 6.7;RH-30: 4.2;U-87 MG: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" 0.3 1.1 0.0 0.3 0.2 0.0 0.1 1.0 2.6 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.3 0.8 1.3 1.0 1.5 0.2 0.1 0.3 0.2 3.4 0.4 0.3 0.1 0.0 1.3 0.8 3.4 0.3 0.0 0.3 0.2 0.7 12.4 0.1 0.1 0.1 0.1 1.6 0.2 1.1 0.6 0.0 0.0 7.7 0.0 0.2 0.1 1.2 0.0 0.4 0.7 0.2 0.1 0.0 0.8 0.1 1.7 0.7 1.2 0.0 0.0 0.0 1.1 0.4 2.9 1.3 0.0 0.1 0.1 0.2 0.0 1.9 0.9 0.0 2.8 0.0 2.4 0.3 0.0 1.2 0.0 9.7 0.0 0.0 2.1 0.6 6.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.2 3.1 1.2 0.1 0.5 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.2 0.0 0.0 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 2.6 1.0 1.5 3.4 0.4 3.4 0.1 0.6 1.2 0.2 0.0 0.6 0.3 0.1 0.1 0.8 0.8 0.6 7.6 0.0 0.4 2.4 0.0 0.2 1.8 0.0 0.5 0.0 0.1 0.0 0.0 2.2 1.8 0.5 0.2 3.5 2.7 8.9 0.0 0.4 1.4 0.0 0.7 2.5 0.1 1.8 0.1 0.1 1.7 7.9 0.7 8.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 5.0 3.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 3.2 1.1 0.0 20.8 0.4 1.6 0.4 0.3 0.1 0.4 0.5 0.1 0.1 0.2 P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 156.7" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "Karpas-707: 40.0;RPMI-8226: 24.8;SK-MEL-30: 41.0;U-266/70: 21.7;U-266/84: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" 2.8 2.5 20.2 5.1 28.5 2.9 2.0 23.1 30.7 6.1 11.3 3.6 1.5 4.1 1.5 1.4 2.3 3.5 1.3 21.8 20.7 0.7 4.6 6.5 5.9 26.3 24.7 8.3 1.4 1.7 1.8 2.9 28.3 1.8 2.3 0.5 2.5 1.8 0.6 13.1 1.8 4.2 21.3 5.9 1.6 1.3 26.2 1.7 1.0 1.0 3.6 2.3 4.4 47.3 0.1 0.0 0.0 1.0 1.1 0.4 0.8 0.1 1.9 0.7 1.7 0.0 0.0 0.1 0.1 0.7 4.3 0.2 0.0 0.0 0.5 1.8 0.1 0.7 0.0 0.1 0.8 1.6 11.6 1.0 0.0 2.0 0.0 0.0 1.9 0.4 0.0 40.0 0.0 0.0 0.2 4.4 0.1 0.0 0.4 3.8 8.9 24.8 0.0 0.0 0.5 2.3 0.2 0.0 41.0 0.0 0.6 7.8 0.0 0.6 0.1 0.1 0.2 21.7 20.2 0.1 2.4 11.8 6.1 0.4 2.9 0.0 1.3 4.5 0.5 0.3 0.6 0.6 2.6 0.2 0.5 0.6 0.3 0.6 3.3 0.4 1.4 0.9 20.2 28.5 23.1 30.7 21.8 20.7 26.3 24.7 28.3 21.3 26.2 47.3 2.0 3.2 4.8 12.1 3.9 6.9 3.0 0.0 1.8 3.9 1.8 2.2 2.4 5.7 3.7 0.0 2.1 3.5 9.0 1.2 0.0 1.2 0.6 0.7 1.6 3.9 0.0 1.7 52.8 0.0 0.9 3.7 0.0 0.3 6.3 2.6 5.3 3.9 23.4 1.7 18.4 0.2 0.0 21.5 35.0 1.5 11.1 34.2 16.0 34.7 21.2 1.3 7.2 87.9 156.7 0.2 0.0 10.5 1.3 1.2 0.1 0.0 3.6 1.0 6.6 3.2 1.9 1.2 0.9 1.0 3.7 4.0 6.6 4.1 0.1 1.0 P2RY14 "GPR105, KIAA0001" ENSG00000174944 "Purinergic receptor P2Y14" Q15391 3 151212117-151278542 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.6;placenta: 31.7" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;dendritic cells: 54.4;Endometrial stromal cells: 35.5;Excitatory neurons: 41.2;granulocytes: 45.7;Langerhans cells: 61.3;Oligodendrocyte precursor cells: 29.1;Sertoli cells: 26.3;Smooth muscle cells: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "eosinophil: 230.1;plasmacytoid DC: 98.0" "Group enriched" "Detected in many" 9 "dendritic cells: 98.0;granulocytes: 230.1" "Cell line enriched" "Detected in single" 68 "HMC-1: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022646 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB022646: " "unprognostic (9.78e-2)" "unprognostic (7.47e-4)" "unprognostic (3.89e-2)" "unprognostic (4.52e-4)" "unprognostic (1.69e-2)" "unprognostic (2.57e-5)" "unprognostic (2.68e-2)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (1.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.72e-5)" "unprognostic (3.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-2)" 7.9 0.8 2.6 10.8 3.8 0.7 7.0 3.4 7.1 5.9 24.6 11.7 6.9 8.0 0.6 20.2 1.1 5.2 5.3 3.2 1.8 2.0 1.0 7.2 9.6 1.3 2.2 1.5 0.6 2.4 0.9 31.7 1.1 0.7 9.7 0.4 1.2 1.3 2.5 1.9 12.0 4.1 1.0 5.7 11.2 0.5 3.8 4.8 2.5 6.4 6.7 9.2 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 10.3 0.4 230.1 1.1 0.3 19.0 3.7 0.6 2.2 13.8 17.0 0.1 0.0 8.9 11.7 0.1 98.0 1.1 2.0 2.6 3.8 3.4 7.1 3.2 1.8 1.3 2.2 1.1 1.0 3.8 3.3 5.8 3.2 0.5 31.0 13.9 2.3 0.0 0.0 0.0 2.1 0.1 0.3 1.8 0.0 0.0 0.0 0.0 0.1 54.4 0.0 0.0 0.0 0.4 1.0 35.5 5.9 0.0 0.4 41.2 0.0 0.2 3.9 0.0 0.7 45.7 0.0 0.0 0.0 0.6 0.0 16.4 0.0 0.0 0.8 61.3 0.5 0.0 22.7 3.6 5.6 1.2 0.4 1.0 29.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.7 0.4 26.3 1.6 29.3 0.0 0.1 0.2 1.7 0.3 4.8 1.5 0.1 0.1 PACC1 "C1orf75, FLJ10874, PAC, TMEM206" ENSG00000065600 "Proton activated chloride channel 1" Q9H813 1 212363928-212414901 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 35.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.1;Extravillous trophoblasts: 7.0;Hofbauer cells: 28.2;Syncytiotrophoblasts: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008540 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "HPA008540: AB_10794083" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (9.23e-2)" "unprognostic (1.02e-1)" "unprognostic (2.74e-2)" "unprognostic (3.09e-2)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.06e-3)" "unprognostic (6.33e-2)" "unprognostic (1.02e-1)" "unprognostic (9.10e-2)" "unprognostic (6.98e-2)" 2.9 2.5 15.0 4.0 24.5 5.8 2.6 24.4 22.9 3.0 10.1 2.0 2.0 2.7 1.9 3.9 1.7 2.8 2.4 15.5 18.8 10.2 1.5 3.8 8.0 26.1 22.3 1.7 3.3 3.6 3.4 4.2 25.3 2.9 2.1 6.0 2.7 1.5 2.1 2.3 3.0 2.9 23.0 5.4 1.8 5.6 20.9 8.6 2.0 1.4 5.2 4.4 3.0 35.1 11.6 8.8 13.0 21.6 7.5 4.0 12.9 6.6 5.2 10.8 9.5 7.4 8.4 13.6 5.3 3.3 10.5 10.1 12.5 6.0 10.7 10.3 13.5 12.8 5.8 9.2 10.7 20.8 19.5 3.6 6.2 9.9 7.2 10.8 12.3 19.7 11.8 7.8 7.5 4.6 23.2 21.4 17.3 5.4 11.5 18.9 14.5 13.1 5.5 5.7 20.1 31.2 7.7 11.3 30.2 12.8 16.8 25.2 10.9 7.0 8.0 16.8 17.3 10.2 17.3 19.1 9.4 18.9 19.9 21.3 8.7 5.3 5.3 11.8 7.0 8.5 4.1 6.2 14.4 8.2 5.8 6.4 0.7 7.0 11.0 20.4 6.4 6.2 15.0 24.5 24.4 22.9 15.5 18.8 26.1 22.3 25.3 23.0 20.9 35.1 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 13.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 7.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.2 0.5 0.0 0.0 0.0 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415522 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.0;smooth muscle: 9.0" "Cell type enhanced" "Detected in some" "Club cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 7.9;Intestinal goblet cells: 5.3;Ionocytes: 6.1;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "RPTEC TERT1: 51.3" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-1)" "unprognostic (7.83e-2)" "unprognostic (6.79e-4)" "unprognostic (2.32e-2)" "unprognostic (1.56e-1)" "unprognostic (5.34e-4)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.12e-1)" 0.5 1.1 3.0 0.3 4.4 0.0 0.9 1.0 11.2 2.3 0.0 3.1 0.9 3.1 2.6 0.7 0.5 0.6 3.5 18.0 3.7 0.8 1.3 3.3 0.0 1.5 4.6 0.3 0.1 0.0 0.5 0.4 1.3 1.0 1.7 0.0 0.7 1.0 0.4 1.0 1.0 9.0 2.3 1.2 1.0 0.1 2.8 0.8 0.2 0.7 0.0 0.6 0.5 2.3 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 51.3 0.0 0.7 1.9 0.0 3.6 0.5 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 4.4 1.0 11.2 18.0 3.7 1.5 4.6 1.3 2.3 2.8 2.3 0.0 3.2 0.5 2.3 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 7.9 5.3 6.1 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 32.6 1.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.2 PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3;pancreas: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Cone photoreceptor cells: 8.4;Horizontal cells: 8.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 16.2" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (4.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (2.36e-1)" "unprognostic (6.46e-2)" "unprognostic (8.24e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-2)" "unprognostic (2.65e-1)" "unprognostic (6.14e-3)" "unprognostic (1.93e-2)" "unprognostic (3.57e-3)" "unprognostic (5.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" 0.8 0.5 1.3 0.3 1.8 0.1 0.7 6.3 2.4 0.9 0.0 0.2 0.3 1.8 2.0 0.0 1.0 1.2 0.1 1.6 0.7 1.5 0.0 0.8 0.2 2.1 1.0 1.1 4.1 0.7 1.5 0.0 2.0 0.4 0.1 2.4 0.5 0.2 0.1 0.1 0.7 1.6 1.5 0.1 0.3 1.3 1.1 0.0 2.1 0.1 0.0 0.2 0.1 2.7 0.0 0.2 0.5 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.3 1.2 0.8 0.0 0.1 0.0 2.4 0.3 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 6.3 2.4 1.6 0.7 2.1 1.0 2.0 1.5 1.1 2.7 0.9 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 7.3 1.2 1.4 0.6 1.5 0.1 0.0 8.4 0.0 0.0 0.2 0.0 0.2 3.2 0.6 2.7 0.6 1.8 0.0 0.0 0.9 0.0 0.6 0.0 0.5 0.0 0.3 0.4 0.0 0.0 8.4 0.0 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.2 0.0 2.5 2.3 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.3 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCSK7 "LPC, PC7, PC8, SPC7" ENSG00000160613 "Proprotein convertase subtilisin/kexin type 7" Q16549 11 117204337-117232525 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 310.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8400 "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (7.11e-2)" "unprognostic (2.90e-2)" "unprognostic (8.33e-3)" "unprognostic (4.24e-2)" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.41e-1)" "unprognostic (8.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.00e-1)" "unprognostic (3.03e-2)" 31.8 16.4 16.4 27.9 17.6 25.7 24.0 15.9 20.9 27.5 16.7 69.5 29.2 72.4 7.6 24.0 35.7 12.9 20.1 19.9 16.6 15.7 19.6 25.6 31.6 18.1 17.0 17.5 29.7 11.8 16.6 13.5 18.0 35.4 37.5 10.0 15.9 11.2 15.6 20.7 35.4 13.5 15.7 30.7 45.1 12.5 18.3 25.0 18.1 10.7 29.2 39.4 22.2 20.2 14.6 27.5 19.1 21.4 23.3 19.0 15.0 48.5 22.2 24.1 23.9 38.3 82.6 24.8 33.5 38.6 31.1 48.0 25.2 34.7 15.5 34.2 24.2 36.7 40.7 17.5 26.1 23.2 49.4 32.9 22.5 33.0 26.4 12.4 41.2 28.0 22.5 22.0 34.8 19.0 31.5 24.3 17.6 63.4 28.1 19.1 16.9 29.5 30.1 33.7 24.9 32.3 39.6 51.1 7.5 14.8 32.3 18.6 36.4 36.4 16.4 31.5 34.3 13.4 8.7 14.0 18.6 33.1 33.3 7.9 7.1 9.0 38.1 9.8 33.0 23.5 29.7 35.6 7.6 18.5 20.8 24.7 5.3 41.0 11.5 8.8 42.8 20.6 16.4 17.6 15.9 20.9 19.9 16.6 18.1 17.0 18.0 15.7 18.3 20.2 47.4 48.1 36.2 44.4 93.3 70.1 50.0 35.2 19.4 124.1 31.2 23.5 8.1 35.8 42.5 47.8 246.0 50.7 97.4 204.9 5.9 27.4 6.4 21.0 40.3 47.5 62.4 27.4 47.2 54.5 39.0 38.5 110.6 36.5 34.1 30.2 77.4 27.8 32.4 87.5 41.4 91.2 24.4 60.6 83.9 7.5 33.5 39.2 53.4 25.3 54.6 21.8 310.0 48.2 62.0 73.7 132.2 39.9 58.7 39.0 98.2 9.2 22.9 178.8 72.3 87.5 107.7 64.4 24.5 27.4 94.3 62.5 127.3 42.7 110.3 53.3 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PEX10 RNF69 ENSG00000157911 "Peroxisomal biogenesis factor 10" O60683 1 2403964-2413797 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 194.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049458, HPA049755" Approved Uncertain Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA049458: AB_2680775, HPA049755: AB_2680867" "prognostic favorable (4.50e-6)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (8.15e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (1.81e-2)" "unprognostic (2.91e-1)" "unprognostic (9.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.16e-6)" "unprognostic (4.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" 14.9 28.9 22.2 2.2 24.3 3.1 13.9 23.5 25.7 10.8 19.7 11.3 6.7 11.4 8.5 17.2 10.0 4.2 16.1 20.6 21.6 18.1 22.0 8.8 4.3 25.4 22.6 12.8 19.8 10.4 18.5 3.8 22.1 16.1 4.4 4.6 14.3 6.9 18.6 14.0 9.6 4.1 23.4 10.2 12.7 22.0 23.3 3.7 13.1 10.2 3.4 12.9 11.3 25.3 18.6 16.9 13.2 7.4 7.9 9.7 11.5 9.6 10.9 14.2 11.3 27.2 13.9 10.8 27.1 11.9 8.7 12.1 11.6 16.3 8.1 16.8 21.9 8.5 17.2 55.3 16.4 14.2 4.2 9.0 9.3 10.8 16.0 10.4 13.9 12.5 9.9 7.4 14.7 26.2 9.1 6.0 9.6 8.0 31.3 7.8 13.8 18.9 17.8 6.3 18.2 15.3 13.0 8.2 29.2 7.1 8.3 3.5 14.8 6.7 5.9 17.2 10.8 19.0 7.6 8.6 17.6 10.9 6.1 1.6 5.8 1.7 3.8 8.7 4.4 5.9 3.3 5.1 9.4 4.9 3.8 3.0 0.6 3.6 7.6 7.8 2.1 4.2 22.2 24.3 23.5 25.7 20.6 21.6 25.4 22.6 22.1 23.4 23.3 25.3 12.8 3.2 4.4 3.3 9.5 8.8 13.7 15.4 15.9 16.8 16.4 15.4 1.1 11.5 8.9 14.7 0.0 26.7 6.7 8.3 35.2 26.8 51.7 8.5 9.0 11.2 13.2 9.2 5.1 30.3 25.2 11.5 12.8 10.3 0.0 22.8 7.5 10.5 22.9 13.5 5.6 10.3 12.2 11.2 7.2 194.7 10.5 9.6 23.2 2.8 18.7 45.2 8.2 8.0 6.7 21.0 7.7 13.5 14.9 14.6 17.5 27.8 8.6 14.8 0.0 15.5 10.9 28.9 22.8 22.4 6.1 27.5 6.9 30.2 14.6 14.1 PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 17.2;Spermatocytes: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA069386: AB_2686135" "unprognostic (1.45e-1)" "unprognostic (6.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (9.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (5.55e-2)" "unprognostic (2.64e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" 3.9 6.8 6.7 3.6 7.2 1.5 5.5 7.9 9.1 5.3 6.7 3.4 3.6 4.3 10.7 3.4 5.6 3.2 9.1 6.8 7.1 8.2 9.0 3.4 4.8 6.8 6.9 8.2 4.0 7.8 4.7 4.7 6.8 5.7 2.9 4.6 5.5 6.9 10.3 4.2 3.5 3.5 7.3 3.9 3.9 6.8 7.0 3.2 7.7 10.8 4.5 3.7 2.7 8.4 2.8 3.7 5.4 4.4 11.0 9.9 3.9 7.3 8.3 6.0 6.3 3.2 3.0 6.4 11.6 4.1 4.9 7.3 6.6 4.8 5.2 2.3 8.7 4.7 3.8 5.9 12.8 6.7 1.2 9.2 9.2 3.7 10.9 7.7 4.6 5.2 7.5 6.6 7.2 2.9 7.9 3.8 2.2 6.3 5.8 3.8 9.3 6.4 7.1 4.2 4.0 4.0 4.6 3.0 9.6 6.5 7.4 3.7 3.7 5.6 3.5 6.3 4.9 13.3 9.9 7.5 6.0 5.1 5.2 2.2 1.5 3.0 1.8 1.1 3.2 2.3 3.0 1.8 1.7 2.6 4.1 3.5 1.0 2.0 1.2 1.7 2.4 1.4 6.7 7.2 7.9 9.1 6.8 7.1 6.8 6.9 6.8 7.3 7.0 8.4 2.7 3.2 0.5 6.5 3.3 0.6 1.9 1.3 1.8 2.1 2.4 2.2 6.3 0.0 2.7 3.7 0.0 6.7 1.4 1.3 3.9 3.5 17.2 1.9 2.3 3.9 1.2 0.8 1.3 1.1 4.1 2.6 2.6 1.5 2.5 2.0 3.3 5.4 2.9 1.7 1.9 1.7 2.0 2.6 0.6 3.0 3.1 1.5 1.8 1.0 0.9 8.3 1.0 4.5 2.8 2.2 1.0 1.5 0.5 2.4 2.7 3.3 1.8 2.2 0.0 2.6 3.7 21.0 10.2 1.4 1.3 5.2 2.8 3.0 2.2 1.3 PEX13 ENSG00000162928 "Peroxisomal biogenesis factor 13" Q92968 2 61017225-61051990 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 125.8;Urothelial cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032141, HPA032142, CAB032689" Enhanced Supported Peroxisomes NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Peroxisomes "CAB032689: AB_2162137, HPA032141: AB_2674176, HPA032142: AB_10669676" "unprognostic (2.44e-3)" "unprognostic (4.10e-2)" "unprognostic (7.84e-3)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (5.08e-2)" "unprognostic (2.05e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (5.42e-2)" "unprognostic (4.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (2.63e-2)" 9.5 8.0 6.6 6.7 7.1 7.4 11.1 9.7 9.2 10.2 10.2 10.2 10.2 9.2 7.5 10.2 6.6 8.8 11.9 6.8 7.4 13.6 25.0 9.3 6.8 6.7 7.1 11.0 11.8 9.6 7.4 9.3 6.8 14.6 10.7 8.8 8.7 5.8 14.6 7.9 9.8 8.1 6.6 6.7 10.1 14.9 7.1 7.3 13.7 13.6 6.7 13.8 9.1 7.7 15.5 11.3 15.7 20.3 14.8 11.5 24.2 15.9 12.3 10.6 10.8 16.9 22.9 10.0 16.7 15.6 19.9 22.8 14.1 19.2 20.0 9.9 9.7 9.2 15.1 28.0 17.5 13.9 10.8 14.2 28.9 14.5 22.3 16.2 19.4 11.3 22.8 8.7 16.3 14.1 10.4 16.6 17.2 28.6 11.2 11.1 17.4 12.7 20.3 38.2 17.7 12.2 17.7 23.7 14.9 18.5 15.8 7.1 15.3 20.2 27.0 11.8 13.6 14.2 11.6 25.0 12.7 14.0 14.5 12.4 3.9 5.9 5.0 3.9 4.7 5.4 5.8 5.5 5.1 4.1 6.1 4.6 3.7 5.5 5.0 4.5 5.4 3.9 6.6 7.1 9.7 9.2 6.8 7.4 6.7 7.1 6.8 6.6 7.1 7.7 12.9 19.2 19.1 14.0 13.8 51.2 35.1 61.9 25.6 11.9 23.0 13.2 21.9 28.6 53.0 22.0 8.4 36.9 13.4 27.6 25.4 28.8 125.8 24.5 16.1 15.1 2.4 9.9 18.8 28.5 43.1 14.5 12.8 28.8 8.2 15.6 13.6 49.3 20.9 16.8 16.8 14.5 36.7 14.6 25.9 28.7 9.6 14.8 16.0 25.3 19.3 12.6 18.6 14.1 19.4 23.2 13.2 11.7 9.9 43.9 28.8 33.2 38.7 15.0 6.6 11.6 18.8 66.8 26.4 21.8 50.3 68.7 15.0 11.4 18.1 112.0 PEX16 ENSG00000121680 "Peroxisomal biogenesis factor 16" Q9Y5Y5 11 45909663-45918812 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043286 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA043286: AB_10794179" "unprognostic (2.48e-1)" "unprognostic (1.95e-2)" "unprognostic (8.14e-2)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (9.06e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-3)" "unprognostic (1.51e-1)" "unprognostic (6.75e-3)" "unprognostic (5.72e-3)" "unprognostic (2.71e-1)" "unprognostic (1.00e-1)" "prognostic favorable (9.06e-4)" 23.4 27.1 22.3 10.9 23.8 20.3 22.2 23.4 24.4 18.2 16.6 20.6 21.3 18.7 6.3 21.3 18.9 10.1 17.0 23.0 22.7 26.7 50.2 16.2 16.6 26.2 23.6 18.3 40.0 10.1 32.0 6.7 23.2 21.7 5.1 4.4 21.6 9.7 18.1 27.2 25.3 6.0 21.9 24.5 27.6 25.8 23.6 11.8 21.8 7.5 8.6 20.1 18.0 26.0 15.0 19.9 6.7 16.8 11.0 13.2 19.4 11.6 15.2 15.5 12.0 22.6 10.7 25.6 15.0 10.9 14.7 27.2 6.9 23.0 3.7 22.4 23.6 16.7 28.8 20.1 34.8 24.9 33.8 21.3 20.1 9.4 15.1 9.1 17.0 21.9 13.4 29.6 10.7 42.0 21.3 32.5 15.1 28.7 20.0 18.4 16.8 29.4 10.0 26.5 17.0 22.7 13.3 27.1 24.5 4.2 40.4 21.1 13.6 14.8 19.0 36.9 21.5 47.1 33.1 16.2 16.2 14.7 16.2 35.3 44.1 36.8 47.9 51.0 44.9 57.0 48.9 49.6 47.8 50.5 44.4 46.7 32.2 44.9 38.6 44.7 61.1 46.1 22.3 23.8 23.4 24.4 23.0 22.7 26.2 23.6 23.2 21.9 23.6 26.0 25.1 3.2 5.4 3.9 35.7 16.6 24.4 47.6 19.4 15.7 25.9 22.4 3.8 22.8 25.1 14.7 10.4 39.9 31.9 45.8 50.9 37.3 25.9 19.7 13.8 21.5 28.1 25.9 4.8 88.7 22.2 15.7 17.9 20.3 21.0 16.2 21.8 68.6 34.2 15.2 5.1 26.5 30.5 37.7 19.7 32.6 19.3 20.0 21.4 3.7 46.6 28.8 26.8 5.0 10.6 55.9 49.2 14.3 27.1 26.1 90.5 68.1 26.4 18.0 32.9 16.8 24.4 27.2 15.4 21.6 21.0 64.0 33.0 19.9 29.6 28.2 PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 216.2" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 74.9;Early spermatids: 147.6;Late spermatids: 296.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Microtubules "HPA063099: AB_2684940" "unprognostic (1.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (3.18e-2)" "unprognostic (5.13e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (3.85e-2)" "unprognostic (4.66e-3)" "unprognostic (4.13e-2)" "unprognostic (2.17e-2)" "unprognostic (2.67e-2)" 8.9 14.9 16.4 6.4 17.5 9.5 11.5 15.9 18.2 13.7 17.0 13.9 18.4 8.3 216.2 34.9 19.2 7.6 21.7 16.6 16.3 13.9 30.9 16.2 10.4 17.8 16.6 11.2 28.9 17.6 15.1 14.2 17.2 16.7 13.3 9.2 18.4 33.4 11.4 48.0 16.0 7.6 16.3 11.3 14.1 28.5 17.3 13.1 19.4 9.5 13.5 10.9 18.8 20.9 27.1 36.3 17.2 15.8 15.2 28.9 27.3 10.9 9.4 15.6 14.2 31.1 46.6 29.0 12.3 8.0 9.4 44.1 27.6 30.2 15.5 35.5 30.9 17.7 14.7 38.4 10.7 23.0 22.0 22.8 41.9 11.6 39.3 10.2 18.0 38.4 38.4 41.8 16.6 39.9 28.0 19.3 32.4 56.7 21.5 44.0 2.0 27.8 30.0 31.6 22.7 22.5 19.7 52.0 12.3 20.1 43.2 9.6 16.5 9.9 9.2 23.8 6.8 26.2 31.3 21.6 12.9 15.3 19.1 3.0 6.4 5.9 9.1 9.2 11.0 11.4 13.2 11.3 9.7 12.7 17.3 11.8 18.2 10.7 9.2 6.6 13.3 8.8 16.4 17.5 15.9 18.2 16.6 16.3 17.8 16.6 17.2 16.3 17.3 20.9 8.4 12.8 10.6 7.5 10.6 31.7 15.1 23.3 33.6 14.1 19.2 18.0 13.7 11.5 13.0 12.9 22.9 74.9 5.2 11.4 1.9 15.6 147.6 11.7 6.6 9.0 3.0 13.2 15.4 21.3 18.4 7.6 10.2 14.7 8.8 13.4 3.6 14.6 16.0 3.3 19.1 10.5 10.2 5.0 8.0 296.8 8.7 5.5 5.4 4.7 8.9 9.3 8.2 10.6 23.0 14.2 9.3 6.8 12.2 9.1 39.8 10.2 15.2 9.5 6.6 11.0 7.2 17.7 21.6 31.1 28.6 29.3 9.4 11.8 20.1 13.0 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PHTF1 PHTF ENSG00000116793 "Putative homeodomain transcription factor 1" Q9UMS5 1 113696831-113759489 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 198.5;Excitatory neurons: 93.4;Inhibitory neurons: 102.6;Late spermatids: 124.5;Spermatocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059486 Approved "Nucleoli,Nuclear bodies" No No "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear bodies" Nucleoli "HPA059486: " "unprognostic (1.52e-1)" "unprognostic (3.33e-1)" "unprognostic (2.58e-2)" "unprognostic (4.54e-2)" "unprognostic (5.92e-2)" "unprognostic (1.62e-2)" "unprognostic (6.55e-2)" "unprognostic (1.30e-1)" "unprognostic (3.30e-3)" "unprognostic (1.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" 5.8 8.0 7.8 6.5 7.7 18.7 3.9 15.5 8.5 5.1 18.9 4.8 3.5 5.0 7.2 2.5 10.5 6.9 5.6 7.4 9.2 8.6 8.1 8.1 5.6 7.7 7.7 3.0 6.8 11.5 12.1 6.8 9.1 4.3 4.9 14.2 4.0 5.1 4.6 1.8 4.1 6.6 6.2 8.6 6.7 30.4 8.0 3.3 4.7 2.9 6.3 6.3 3.0 7.3 28.5 14.7 40.5 21.5 20.1 18.0 9.4 25.6 34.0 22.3 36.4 16.0 22.3 8.1 35.3 17.8 16.6 15.3 15.6 10.2 25.7 33.8 15.5 19.6 30.0 18.5 16.4 24.4 26.7 15.0 2.7 29.9 6.6 32.3 41.9 0.0 12.0 36.1 27.4 41.9 0.3 23.6 32.4 10.6 21.3 25.5 60.8 16.3 35.9 12.3 27.7 26.0 28.7 13.9 16.1 20.9 5.6 19.6 44.4 17.5 23.8 32.6 25.2 48.9 53.5 14.8 43.0 20.8 48.6 1.4 1.2 2.5 1.3 0.7 1.1 1.7 1.6 1.6 2.1 0.7 0.0 1.2 2.8 2.2 0.9 1.5 2.9 0.9 7.8 7.7 15.5 8.5 7.4 9.2 7.7 7.7 9.1 6.2 8.0 7.3 12.5 6.4 10.5 34.3 16.7 2.4 6.8 7.9 6.8 30.1 8.7 6.0 8.5 14.3 10.0 5.5 54.2 19.9 22.9 4.7 9.8 12.6 198.5 51.7 18.7 19.7 19.2 12.0 93.4 20.9 10.1 10.8 15.8 9.6 21.5 13.6 10.0 9.0 12.6 28.6 102.6 3.1 18.3 13.4 19.2 124.5 8.1 18.0 5.4 21.5 11.0 6.6 18.6 25.1 13.6 19.6 1.2 9.1 31.0 8.3 1.4 5.9 58.7 43.9 0.0 13.5 12.2 130.8 41.3 6.1 1.7 26.4 23.1 16.9 4.6 7.7 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 209.1;Inhibitory neurons: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 18.8 21.6 45.2 19.2 61.0 24.1 16.8 2.1 74.4 20.4 9.6 23.7 15.8 24.2 9.9 14.3 19.5 13.5 21.5 65.3 9.0 21.3 25.2 19.1 20.5 14.6 4.8 21.4 18.7 34.5 25.2 17.9 14.5 19.5 14.9 27.7 16.5 16.9 23.6 15.1 22.9 21.9 0.0 21.0 26.0 25.7 8.6 34.3 18.0 15.9 18.0 22.2 16.9 43.3 24.5 20.2 17.4 26.3 48.7 29.1 24.9 21.6 32.6 31.3 30.4 15.9 10.2 45.6 12.6 43.9 30.7 21.1 33.4 20.9 19.0 38.9 50.9 47.1 27.1 18.3 24.3 47.0 36.1 26.2 12.9 26.7 14.7 20.4 25.8 13.8 130.2 37.6 24.6 33.8 41.6 16.0 13.8 43.4 20.6 41.1 38.1 8.5 17.3 38.3 42.6 31.0 28.4 32.6 22.6 24.3 27.6 21.3 26.2 56.4 29.1 21.1 18.5 28.6 31.3 35.8 37.4 33.2 24.1 2.1 3.7 5.3 3.2 3.8 3.1 3.4 3.6 3.9 2.5 3.4 3.6 5.0 5.1 7.0 3.3 8.5 4.3 2.2 45.2 61.0 2.1 74.4 65.3 9.0 14.6 4.8 14.5 0.0 8.6 43.3 13.0 12.8 30.4 65.6 14.7 10.1 6.5 7.6 9.6 35.8 17.2 14.4 30.2 20.0 10.5 7.3 47.9 17.8 21.5 19.7 1.9 9.7 36.5 10.3 17.9 15.5 19.2 12.4 209.1 6.3 19.6 15.6 38.7 15.8 12.0 13.8 11.4 19.7 20.1 37.0 127.4 16.7 10.2 21.0 12.6 25.3 19.9 20.2 10.6 39.4 10.9 23.1 16.5 50.3 88.4 8.9 9.7 24.0 15.5 10.1 23.8 10.3 9.6 25.4 26.3 14.5 19.3 35.3 29.6 14.1 9.8 20.0 15.3 26.1 14.3 8.9 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.5;Suprabasal keratinocytes: 55.0;Urothelial cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 2.1 2.9 2.2 2.9 2.7 9.2 3.1 2.0 3.6 2.8 0.8 3.7 1.9 3.0 3.5 5.1 2.8 3.7 2.0 1.6 1.8 3.8 4.5 6.7 3.5 2.8 2.7 2.4 4.0 3.3 0.6 3.6 2.2 2.7 3.7 4.5 4.6 1.7 1.3 1.4 2.4 2.5 2.2 2.0 2.8 2.6 2.3 4.0 4.4 1.3 4.7 10.3 1.9 5.8 14.5 8.3 9.1 5.0 2.6 2.8 7.0 3.7 5.7 7.4 7.3 9.2 6.5 6.6 2.9 2.9 9.0 5.8 14.3 11.4 12.6 6.1 9.5 5.5 11.0 5.8 4.5 8.8 2.9 3.3 8.1 10.0 16.0 2.4 5.0 5.2 6.4 7.0 5.1 9.2 9.0 3.4 4.7 5.5 8.2 3.0 12.4 10.7 5.6 9.4 6.2 9.4 6.9 6.8 14.4 8.7 6.6 7.4 4.2 6.2 2.4 14.0 7.3 5.4 7.2 9.9 9.4 5.6 7.9 22.9 3.8 4.3 2.6 6.3 3.7 3.0 4.1 2.6 3.9 2.1 3.8 2.9 5.2 1.8 8.6 2.6 4.1 2.7 2.2 2.7 2.0 3.6 1.6 1.8 2.8 2.7 2.2 2.2 2.3 5.8 6.4 19.2 83.5 6.8 7.2 29.6 41.9 10.6 13.6 3.5 13.2 10.5 6.9 5.7 20.1 3.7 0.0 6.3 7.4 8.4 11.7 7.6 5.4 30.8 9.8 7.9 10.7 9.3 2.2 5.8 10.2 12.7 17.9 45.6 33.6 3.0 3.6 4.4 8.8 3.3 2.0 5.0 2.0 8.4 43.4 4.4 3.1 18.1 28.4 2.8 3.6 4.2 4.1 1.0 7.7 8.3 5.1 3.0 5.5 32.0 2.1 6.6 19.8 3.0 13.1 10.6 16.3 2.7 3.7 35.5 55.0 28.0 11.7 2.9 6.0 62.2 PIGH GPI-H ENSG00000100564 "Phosphatidylinositol glycan anchor biosynthesis class H" Q14442 14 67581955-67600286 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autism spectrum disorder, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031624 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA031624: AB_10601046" "unprognostic (1.59e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (3.47e-2)" "unprognostic (8.25e-3)" "unprognostic (8.69e-3)" "unprognostic (3.26e-3)" "unprognostic (1.19e-1)" "unprognostic (2.73e-1)" "unprognostic (6.17e-3)" "unprognostic (1.39e-1)" "prognostic favorable (2.68e-7)" "unprognostic (7.42e-2)" "unprognostic (1.42e-2)" "unprognostic (7.00e-2)" "unprognostic (3.73e-1)" 15.4 34.2 19.9 8.2 23.6 27.2 19.2 23.4 26.4 25.9 22.5 14.2 12.6 14.0 36.6 14.0 15.5 13.6 15.1 19.4 23.4 34.7 23.9 13.7 11.9 23.9 22.4 23.8 29.2 66.7 13.6 12.5 23.9 28.9 11.6 47.6 26.2 16.0 32.2 19.9 16.1 10.9 22.6 16.5 19.6 20.7 22.7 11.8 28.8 24.7 13.3 16.4 14.4 27.4 24.5 15.6 14.7 30.3 32.1 12.3 12.4 13.3 16.1 18.2 17.7 25.4 8.3 16.5 12.9 9.1 30.4 17.5 26.3 18.9 20.1 25.4 34.8 17.3 12.4 26.1 25.2 12.8 19.9 17.9 23.8 13.7 21.0 5.6 11.8 28.5 39.7 11.5 13.3 21.4 18.8 21.4 2.7 33.8 41.9 6.3 14.8 9.9 19.6 20.0 18.3 22.1 10.1 19.4 33.8 10.8 22.0 12.5 6.1 18.1 23.2 23.8 15.8 21.9 15.2 11.2 13.9 27.1 25.7 42.0 24.8 52.5 44.9 35.1 58.5 61.8 46.5 41.8 25.4 72.0 48.3 45.0 12.1 51.5 45.7 29.6 48.2 35.0 19.9 23.6 23.4 26.4 19.4 23.4 23.9 22.4 23.9 22.6 22.7 27.4 14.8 3.2 14.1 5.5 23.6 20.6 20.4 37.1 19.4 35.5 22.8 25.9 4.9 22.8 17.8 22.0 35.5 29.8 28.7 9.5 29.4 22.3 12.1 20.3 10.5 16.1 7.2 13.2 8.0 37.1 28.7 20.8 9.2 10.9 7.0 13.4 13.9 14.6 22.7 26.9 10.4 14.9 26.4 7.6 12.9 9.4 21.5 12.3 35.6 7.5 7.0 96.6 23.7 8.5 10.3 24.3 10.6 21.1 31.2 26.8 29.4 31.3 12.2 45.5 0.0 22.7 18.7 78.8 59.5 17.7 20.9 56.4 20.7 34.6 14.1 18.2 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 78.9;Late spermatids: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.3 23.9 7.1 3.8 8.0 30.4 15.0 2.0 12.0 15.4 8.6 16.2 7.5 18.3 1.4 13.2 16.5 2.8 13.3 9.6 5.2 30.7 19.0 17.9 2.5 6.6 9.7 15.6 21.9 9.4 25.4 3.3 6.5 19.4 1.1 1.2 19.3 5.8 18.4 15.7 12.6 1.6 3.5 15.0 17.0 28.1 6.0 2.7 31.1 1.7 1.2 15.8 12.1 4.3 14.2 21.9 7.3 10.3 4.6 2.7 13.9 14.7 5.6 6.3 6.6 14.6 12.9 7.6 18.6 3.3 5.5 22.2 3.3 6.4 1.3 21.9 30.4 11.4 23.8 10.8 8.9 10.1 10.2 5.2 9.8 10.2 2.0 4.0 6.1 13.7 26.1 4.1 2.1 20.7 18.3 11.4 10.0 3.0 21.9 36.6 6.4 17.7 5.6 5.6 13.2 21.4 16.8 7.6 10.8 2.3 17.3 6.9 14.5 10.4 13.7 11.7 10.4 15.8 5.0 6.0 4.8 5.4 10.4 0.9 2.8 1.6 2.8 3.1 2.4 2.3 2.3 2.6 2.7 2.5 2.5 1.6 3.0 3.3 3.7 5.6 2.4 2.6 7.1 8.0 2.0 12.0 9.6 5.2 6.6 9.7 6.5 3.5 6.0 4.3 9.7 16.0 20.3 14.0 6.9 4.8 6.6 8.4 5.2 12.1 15.8 11.0 8.4 4.3 10.6 40.5 4.2 10.5 8.8 31.5 3.9 19.3 33.6 21.0 7.8 9.0 20.3 78.9 19.3 17.4 8.4 9.4 16.3 11.4 8.2 19.7 6.4 16.4 9.5 10.1 13.8 13.0 8.2 9.1 4.4 61.4 7.5 8.2 16.0 3.7 7.7 14.6 10.3 7.5 6.6 14.1 11.6 7.2 9.1 6.9 7.6 12.4 23.3 13.7 0.0 7.7 9.9 30.1 13.6 6.2 4.8 5.9 7.8 11.1 16.9 5.0 PIGS ENSG00000087111 "Phosphatidylinositol glycan anchor biosynthesis class S" Q96S52 17 28553383-28571794 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018149 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA018149: AB_1855373" "unprognostic (2.29e-2)" "unprognostic (1.37e-2)" "unprognostic (3.89e-1)" "unprognostic (2.52e-1)" "unprognostic (6.61e-2)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.65e-1)" "unprognostic (9.09e-2)" "unprognostic (2.25e-3)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (2.90e-2)" "unprognostic (1.23e-1)" "unprognostic (8.06e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (5.31e-4)" 25.0 15.5 8.3 15.5 8.5 25.3 11.4 8.2 8.6 12.9 18.6 25.5 30.9 12.0 3.3 23.5 20.1 15.6 25.4 10.5 9.1 16.6 4.9 20.2 18.9 8.8 9.4 13.3 16.8 28.5 3.3 17.4 8.8 17.7 15.7 3.4 14.8 16.2 31.4 18.5 32.2 16.1 7.8 18.2 26.9 13.4 8.7 17.5 24.3 19.7 13.7 17.7 5.3 8.0 34.7 57.4 26.5 67.9 51.1 38.2 40.1 42.3 34.5 44.4 58.1 60.4 33.8 22.3 62.9 57.8 43.1 64.5 32.4 48.2 16.6 65.8 92.5 30.1 45.3 26.2 47.8 58.5 73.8 46.7 33.6 27.8 37.8 44.5 60.3 37.8 89.3 34.1 38.5 42.6 36.9 40.2 13.2 77.9 17.6 31.2 87.8 73.6 30.6 36.9 54.3 37.7 60.3 115.4 32.8 26.4 105.4 69.5 52.2 31.5 32.5 27.1 35.0 56.5 84.0 17.0 56.6 56.8 45.1 86.2 60.4 78.9 34.3 55.0 31.0 23.5 27.5 32.5 64.9 22.3 28.8 24.0 29.4 43.0 39.6 49.8 45.2 46.3 8.3 8.5 8.2 8.6 10.5 9.1 8.8 9.4 8.8 7.8 8.7 8.0 15.7 44.8 21.4 10.7 15.9 8.3 11.3 21.1 13.6 20.5 20.5 17.1 40.7 20.0 18.8 46.0 64.6 35.0 31.6 48.5 11.7 43.5 9.5 15.3 15.7 18.7 40.7 17.9 10.9 26.3 53.4 14.9 18.3 21.5 3.8 17.1 26.4 7.9 31.1 52.2 12.6 28.3 24.4 28.1 8.0 13.1 23.9 22.9 7.2 1.9 66.1 17.5 93.7 9.0 11.7 22.5 21.6 22.6 16.8 15.0 49.0 19.1 14.4 56.1 6.6 12.3 15.9 74.2 62.0 19.3 12.5 36.4 21.8 25.0 27.6 12.4 PIP4P1 "C14orf9, MGC26684, TMEM55B" ENSG00000165782 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1" Q86T03 14 20457681-20461465 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.4;Hofbauer cells: 54.9;Syncytiotrophoblasts: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048528 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA048528: AB_2680427" "unprognostic (1.84e-1)" "unprognostic (6.23e-2)" "unprognostic (1.81e-1)" "unprognostic (7.07e-2)" "unprognostic (2.04e-1)" "unprognostic (8.51e-2)" "unprognostic (1.71e-2)" "unprognostic (3.37e-3)" "unprognostic (4.94e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.85e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.80e-2)" "unprognostic (1.47e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" 23.6 27.3 37.2 13.6 38.3 49.0 22.4 36.5 38.6 22.2 32.1 25.4 17.8 21.6 27.0 25.5 21.6 13.4 22.9 38.2 38.8 27.4 25.1 23.9 18.8 38.3 37.8 20.9 24.4 30.6 28.3 16.6 40.4 23.6 15.6 26.1 23.5 15.4 35.1 33.6 28.7 15.9 36.0 31.3 27.8 21.2 38.2 16.9 22.5 22.6 21.1 24.2 21.3 36.5 21.1 32.4 21.3 25.1 32.7 20.2 39.5 19.6 38.1 26.2 31.5 19.3 33.2 18.8 16.5 24.6 75.9 21.6 26.3 21.5 22.9 24.9 19.7 13.5 15.5 28.6 44.6 25.2 26.7 26.3 28.9 30.2 30.5 23.8 24.5 28.7 11.5 37.1 21.9 24.2 34.3 22.1 14.3 32.9 44.5 25.1 20.7 12.6 24.6 46.6 30.7 23.0 20.1 32.6 25.8 18.3 16.4 23.6 17.2 23.8 30.1 36.0 17.6 42.0 58.0 27.6 16.5 19.2 26.5 1.3 3.2 7.3 4.2 2.3 3.5 12.4 5.2 4.8 4.1 10.3 5.8 6.1 4.1 4.4 2.0 10.4 4.5 2.5 37.2 38.3 36.5 38.6 38.2 38.8 38.3 37.8 40.4 36.0 38.2 36.5 23.5 9.6 12.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 29.8 22.7 0.0 0.0 3.1 22.0 0.0 78.4 23.8 0.0 19.6 36.8 0.0 19.1 13.5 9.1 0.0 0.0 0.0 40.0 35.0 8.2 0.0 24.3 3.8 15.6 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 12.9 0.0 0.0 0.0 0.0 36.9 0.0 0.0 7.6 0.0 0.0 20.4 5.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 167.2 9.9 18.4 0.0 0.0 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 26.2;Cytotrophoblasts: 32.6;Distal tubular cells: 49.0;Extravillous trophoblasts: 31.1;Hofbauer cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 76.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 11.9 13.9 13.2 6.6 15.7 30.0 7.4 16.5 20.1 9.2 20.2 14.6 2.8 10.5 4.2 5.9 7.2 11.0 20.7 13.3 20.4 10.0 3.8 5.5 6.9 16.5 16.4 10.6 3.3 10.9 7.9 8.8 18.2 8.7 4.8 11.0 7.3 12.2 13.5 6.5 5.3 13.5 16.4 8.3 6.5 6.9 17.5 9.5 6.6 14.8 5.4 9.9 6.6 21.0 4.8 2.9 16.8 10.2 27.2 30.6 3.5 19.3 24.2 10.2 15.1 1.9 8.1 9.4 2.6 19.9 10.3 1.1 4.2 7.0 13.6 8.1 7.3 13.9 2.9 1.5 23.6 3.3 12.2 17.2 4.4 12.8 9.6 27.4 9.8 2.7 7.4 31.0 35.6 3.3 10.4 9.5 8.6 0.0 9.8 3.9 6.9 11.2 14.9 3.0 2.0 9.7 1.5 6.6 28.4 11.4 0.2 6.3 15.1 18.5 7.1 11.2 9.0 12.0 7.0 6.0 31.6 6.4 25.2 0.9 11.6 10.8 1.3 5.9 2.3 2.7 3.1 1.7 10.8 1.9 4.8 1.9 76.9 2.4 2.2 6.0 2.8 6.1 13.2 15.7 16.5 20.1 13.3 20.4 16.5 16.4 18.2 16.4 17.5 21.0 26.2 0.0 2.8 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.5 11.2 0.0 0.0 3.1 9.2 0.0 32.6 7.7 0.0 49.0 18.0 0.0 0.8 11.7 5.2 0.0 0.0 0.0 8.9 31.1 18.7 0.0 1.0 8.8 4.1 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.1 0.0 0.0 13.1 1.5 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 10.9 3.7 14.3 0.0 0.0 PIRT ENSG00000233670 "Phosphoinositide interacting regulator of transient receptor potential channels" P0C851 17 10822470-10838087 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.0" "Cell type enhanced" "Detected in single" "Astrocytes: 2.6" "Cancer enriched" "Detected in single" 40 "glioma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042337 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "Plasma membrane" "HPA042337: AB_10794795" "unprognostic (2.95e-1)" "unprognostic (2.19e-2)" "unprognostic (7.57e-2)" "unprognostic (6.58e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (2.85e-3)" 0.0 2.5 7.5 1.1 8.7 0.0 0.0 11.5 6.8 0.0 1.7 4.0 1.0 0.0 0.0 0.1 0.2 0.1 0.0 5.4 11.6 0.0 0.0 0.0 0.0 22.4 16.5 0.0 0.0 0.0 0.0 0.0 14.0 0.1 2.6 0.2 0.0 0.0 0.0 0.3 1.9 0.8 11.8 0.0 1.4 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.5 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 8.7 11.5 6.8 5.4 11.6 22.4 16.5 14.0 11.8 24.0 10.8 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 148.6;Microglial cells: 95.5;Oligodendrocyte precursor cells: 178.9;Oligodendrocytes: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 137.2;BJ hTERT+: 207.1;fHDF/TERT166: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" 30.7 24.2 9.6 13.9 12.2 10.7 18.6 10.0 12.0 40.0 7.3 32.5 10.7 61.1 14.7 12.7 39.3 26.9 19.7 9.0 8.9 48.6 15.0 22.2 11.5 10.4 11.2 47.7 14.8 27.9 9.0 24.5 10.0 23.3 13.2 14.0 9.7 39.2 5.8 10.3 14.8 53.7 9.1 10.9 20.0 10.3 11.9 7.6 16.4 11.7 8.7 20.6 18.4 14.6 7.4 40.8 44.9 23.2 101.8 67.6 13.3 137.2 207.1 62.9 62.2 2.0 12.8 4.0 29.3 166.4 24.0 9.1 8.1 20.4 54.5 21.2 7.1 6.6 21.8 4.3 56.5 16.2 12.9 56.4 9.1 49.4 26.4 85.6 28.8 7.6 0.9 10.9 55.5 14.4 11.4 7.7 23.4 5.3 6.7 21.5 26.8 6.0 55.6 17.2 9.0 20.1 25.5 1.2 32.5 45.0 9.7 12.1 44.7 59.1 12.9 16.8 18.8 8.7 2.9 4.4 35.2 2.5 55.3 1.4 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.2 0.3 0.1 0.4 0.1 0.1 9.6 12.2 10.0 12.0 9.0 8.9 10.4 11.2 10.0 9.1 11.9 14.6 14.8 3.2 6.3 59.4 3.5 7.4 5.3 7.4 23.3 16.7 7.4 11.3 7.1 18.6 7.2 69.9 10.4 10.4 2.7 0.6 0.0 14.0 0.3 10.3 41.7 19.2 6.7 13.5 129.1 3.8 3.4 42.0 2.0 11.1 1.3 12.7 21.4 10.6 12.2 26.9 148.6 3.4 4.1 5.0 6.8 1.1 23.0 9.8 23.2 95.5 9.5 17.3 4.1 178.9 219.4 2.2 4.6 50.8 3.1 6.5 3.9 17.0 12.3 1.9 26.3 53.0 31.5 0.8 3.8 13.3 6.7 2.7 6.1 11.5 2.8 3.4 PLLP "PMLP, TM4SF11" ENSG00000102934 Plasmolipin Q9Y342 16 57248547-57284672 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 844.1;choroid plexus: 1086.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 161.5;Glandular and luminal cells: 134.3;Oligodendrocyte precursor cells: 140.2;Oligodendrocytes: 193.4;Pancreatic endocrine cells: 119.0;Proximal enterocytes: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "naive CD4 T-cell: 14.5;naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 8 "T-cells: 14.5" "Cell line enhanced" "Detected in many" "EFO-21: 27.8;Hep G2: 81.1;OE19: 79.6;RPTEC TERT1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041862 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA041862: AB_2677712" "unprognostic (7.96e-2)" "unprognostic (2.07e-3)" "unprognostic (3.86e-2)" "prognostic favorable (2.80e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (5.64e-2)" "unprognostic (6.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (6.21e-9)" "unprognostic (2.06e-2)" "unprognostic (9.06e-3)" "unprognostic (3.86e-1)" "unprognostic (3.32e-2)" 14.5 2.8 549.6 2.3 673.5 2.3 12.1 352.7 646.8 24.6 1086.0 10.5 33.5 6.3 2.4 34.3 22.6 27.4 8.4 489.4 603.1 41.0 9.8 50.7 2.4 769.3 601.6 3.0 52.5 14.8 4.4 2.6 775.8 12.8 12.6 2.0 41.9 27.9 3.8 99.5 33.4 2.4 689.1 19.6 79.8 6.2 844.1 1.1 12.8 6.3 4.9 9.6 26.1 779.6 1.6 5.7 7.1 1.4 0.0 0.1 3.6 1.1 0.3 0.4 0.3 15.9 6.8 0.5 27.8 0.0 1.8 5.2 3.3 5.0 0.1 1.6 2.7 7.3 3.0 81.1 1.0 0.7 1.8 0.2 1.2 0.1 0.6 3.6 8.0 1.7 1.3 1.9 0.1 2.0 0.9 1.8 5.9 79.6 2.3 0.9 1.3 1.4 33.5 17.1 1.6 2.8 1.9 2.2 3.3 2.2 11.7 2.2 6.0 1.2 1.6 1.0 1.3 1.4 1.7 0.9 1.6 0.5 4.7 1.7 1.0 0.7 0.8 0.5 0.6 0.7 2.2 0.6 0.2 1.2 14.5 5.7 1.8 0.6 0.5 0.5 0.6 2.2 549.6 673.5 352.7 646.8 489.4 603.1 769.3 601.6 775.8 689.1 844.1 779.6 18.4 64.1 26.5 0.3 1.4 13.9 15.9 61.4 22.8 2.7 23.8 23.6 3.2 161.5 26.4 90.1 2.1 2.2 1.8 26.6 15.6 61.3 0.9 66.9 12.4 20.5 1.2 5.3 0.5 70.2 1.3 5.1 76.0 134.3 3.8 13.4 11.0 4.2 0.7 5.0 0.7 23.7 93.6 0.8 2.2 1.5 4.7 2.1 3.6 25.3 1.3 0.5 0.0 140.2 193.4 119.0 66.8 22.2 1.3 5.8 149.9 28.6 4.0 7.7 0.0 3.6 4.0 1.6 3.3 54.2 42.8 1.1 2.4 1.2 36.1 13.3 PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 7004.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 4822.5" "Group enriched" "Detected in many" 22 "glioma: 160.5;melanoma: 75.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SK-MEL-30: 241.0;WM-115: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004128: AB_1079635" "unprognostic (5.72e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-2)" "unprognostic (4.09e-3)" "unprognostic (1.32e-1)" "unprognostic (3.95e-2)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-5)" "unprognostic (4.91e-2)" "unprognostic (1.86e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-2)" 7.3 15.7 2252.5 4.2 4296.1 0.1 5.4 4251.8 3472.7 17.8 1056.0 73.9 6.3 6.8 6.7 9.9 7.3 9.6 30.1 2314.1 2859.4 2.9 2.0 1.2 0.4 5976.3 3571.3 5.7 2.5 83.1 6.4 0.0 5342.5 21.1 14.9 7.5 6.7 30.0 2.4 24.4 22.4 22.7 3919.9 0.5 15.4 33.5 3592.5 3.8 3.4 6.8 0.4 12.9 21.8 7004.9 0.2 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.8 1.9 0.0 0.0 0.2 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 4.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 241.0 6.3 0.1 0.2 0.0 0.1 0.4 0.1 0.2 0.0 0.3 0.2 4.0 0.0 139.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2252.5 4296.1 4251.8 3472.7 2314.1 2859.4 5976.3 3571.3 5342.5 3919.9 3592.5 7004.9 0.5 0.0 0.0 23.8 0.1 15.9 0.3 0.0 6.2 1.7 0.2 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 9.7 0.0 0.0 13.3 0.0 0.0 0.0 188.3 3.3 0.0 0.1 0.0 11.2 0.0 0.0 0.0 5.8 3.1 7.5 0.8 396.6 17.8 0.0 30.7 0.0 31.2 4822.5 0.0 0.0 3.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 3.1 2.4 0.6 0.3 0.8 2.6 0.0 0.2 5.6 0.0 0.1 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;kidney: 15.6" "Group enriched" "Detected in some" 4 "Distal tubular cells: 37.2;Early spermatids: 12.3;Proximal tubular cells: 39.0" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 3.7;SCLC-21H: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" 0.0 0.1 9.7 0.0 12.8 0.0 0.7 7.1 12.7 0.1 5.2 0.2 0.0 0.0 2.8 0.0 0.2 0.0 0.0 10.4 9.3 15.6 3.6 1.4 0.0 10.2 9.1 0.0 0.3 0.0 0.1 0.0 9.8 0.2 0.1 1.5 0.3 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.1 0.6 10.9 0.4 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 9.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 12.8 7.1 12.7 10.4 9.3 10.2 9.1 9.8 9.6 10.9 11.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 2.3 0.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 37.2 0.0 12.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 39.0 0.0 1.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.8;brain: 21.1;fallopian tube: 11.1" "Cell type enriched" "Detected in some" 7 "Endometrial ciliated cells: 37.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 61.8;THP-1: 128.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.0 0.0 16.8 0.2 14.1 9.8 2.2 0.0 21.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 11.1 0.1 0.1 14.2 11.5 0.0 0.0 2.3 0.1 4.1 8.2 0.3 0.0 0.2 0.4 0.0 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 2.3 0.2 0.1 3.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.5 12.2 0.0 0.0 0.0 6.9 0.2 0.1 0.0 0.0 0.7 0.1 0.1 8.4 0.1 0.1 0.3 2.3 0.0 0.0 0.0 5.2 0.0 1.6 0.0 0.5 4.4 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 12.0 0.3 0.0 1.1 0.0 61.8 9.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 15.5 0.3 0.0 0.0 6.3 5.4 128.9 0.1 0.2 0.2 0.3 0.1 0.2 0.5 0.2 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 14.1 0.0 21.1 14.2 11.5 4.1 8.2 1.5 2.3 13.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 37.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 1.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.1 5.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 PMIS2 IFITMD9 ENSG00000283758 "PMIS2 transmembrane protein" A0A1W2PS18 19 35586161-35587296 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 17 "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 21: Non-specific - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 404.1;Hofbauer cells: 558.3;Leydig cells: 324.3;Melanocytes: 343.3;Proximal enterocytes: 580.6;Skeletal myocytes: 288.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.2;eosinophil: 43.0;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 22 "dendritic cells: 23.8;granulocytes: 43.0" "Cell line enhanced" "Detected in many" "ASC diff: 383.5;HMC-1: 263.7;SuSa: 333.9;WM-115: 448.8" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" 275.6 45.4 113.6 55.1 161.0 4.9 184.5 153.2 140.7 192.2 77.9 212.2 41.7 142.1 36.5 68.2 163.4 106.5 167.6 113.5 129.0 53.5 11.7 208.4 27.8 163.3 144.2 102.9 22.8 10.8 26.3 201.9 159.9 81.2 74.7 6.5 77.5 80.6 252.4 112.7 239.1 122.0 135.0 27.9 96.2 20.7 141.1 17.3 95.3 127.0 21.8 208.9 157.4 216.7 7.0 44.1 61.9 62.2 383.5 167.1 12.6 60.5 68.8 58.7 38.0 48.7 1.1 0.1 7.0 172.3 22.7 0.7 74.0 1.1 15.4 0.2 13.9 4.3 76.7 17.2 201.8 0.1 263.7 126.9 1.1 32.6 1.8 72.1 66.1 2.8 24.5 0.8 33.2 6.1 0.2 2.0 3.5 4.0 74.7 22.0 39.3 0.0 44.6 4.8 0.1 40.6 16.6 0.6 134.2 333.9 0.2 0.5 81.4 12.7 45.7 216.9 62.0 0.5 0.1 0.3 84.7 0.1 448.8 32.2 1.4 43.0 0.0 0.9 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.2 0.1 0.2 23.8 0.0 0.9 113.6 161.0 153.2 140.7 113.5 129.0 163.3 144.2 159.9 135.0 141.1 216.7 86.6 28.9 11.5 50.9 2.8 90.1 6.7 6.1 9.6 1.4 43.0 82.7 68.4 4.3 7.4 0.0 0.0 8.8 2.5 9.1 3.9 4.5 17.7 20.1 118.6 148.0 4.8 10.1 3.7 3.3 23.1 404.1 2.6 11.0 119.7 25.0 88.5 0.9 558.3 0.0 1.8 23.8 0.0 23.4 116.8 11.0 324.3 93.0 343.3 29.0 11.8 61.6 0.0 46.8 217.1 1.7 25.2 246.4 1.9 4.9 580.6 0.7 3.0 2.2 230.1 288.8 141.1 3.0 4.8 3.0 103.0 19.0 8.7 49.2 17.9 5.2 POLR1E "FLJ13390, FLJ13970, PAF53, PRAF1, RPA49" ENSG00000137054 "RNA polymerase I subunit E" Q9GZS1 9 37485948-37503697 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022527, HPA052400" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli fibrillar center" "HPA022527: AB_1854924, HPA052400: AB_2681815" "prognostic favorable (2.27e-4)" "unprognostic (2.09e-1)" "unprognostic (9.90e-3)" "unprognostic (1.10e-2)" "unprognostic (7.16e-3)" "unprognostic (2.07e-1)" "unprognostic (1.09e-2)" "unprognostic (7.14e-2)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.80e-1)" "unprognostic (2.48e-1)" "unprognostic (1.07e-1)" "unprognostic (4.96e-2)" "unprognostic (5.23e-1)" "unprognostic (1.58e-1)" "unprognostic (4.24e-2)" 20.8 15.3 9.4 14.6 9.7 13.1 24.0 9.7 9.0 22.7 7.0 17.9 8.5 24.3 14.8 13.9 20.0 12.6 18.4 8.8 10.6 8.4 29.7 11.9 19.3 9.0 9.5 42.4 27.9 11.5 9.4 8.3 9.4 14.0 10.9 8.9 18.0 17.4 19.1 15.7 10.9 22.5 10.2 10.9 15.0 9.1 9.6 17.0 13.7 10.5 21.6 17.9 17.0 10.4 58.5 53.7 29.0 46.2 53.2 67.8 18.9 50.6 19.5 51.2 45.0 46.4 18.9 84.1 23.8 58.5 34.9 23.8 71.5 60.0 64.2 81.9 33.6 40.4 68.0 33.3 39.7 78.2 27.5 72.7 20.9 100.4 85.7 32.2 26.5 46.0 107.5 36.0 45.6 28.0 54.5 26.8 51.7 39.7 43.5 47.8 26.7 40.5 26.7 21.4 41.3 33.9 33.7 26.7 43.8 23.8 26.0 51.4 18.3 60.3 91.9 52.3 102.2 19.5 29.6 87.7 20.8 48.8 51.2 0.0 3.5 2.2 14.2 6.0 22.7 10.1 13.5 14.5 5.6 11.5 16.6 14.7 1.1 13.1 5.2 3.9 8.0 7.5 9.4 9.7 9.7 9.0 8.8 10.6 9.0 9.5 9.4 10.2 9.6 10.4 7.2 0.0 8.4 1.6 20.4 28.3 23.7 10.9 21.1 7.0 13.2 15.2 8.6 14.3 7.4 0.0 4.2 15.6 20.0 4.3 7.9 13.8 5.6 5.4 20.1 7.1 1.8 15.4 1.8 21.6 21.4 16.1 8.6 6.7 8.8 14.0 3.9 18.7 7.4 3.3 2.4 7.7 6.1 10.3 8.0 10.7 14.9 8.1 5.4 3.7 9.2 9.2 12.3 1.5 2.1 14.1 3.0 15.1 28.3 23.6 3.1 5.9 4.1 6.9 0.0 22.1 15.9 20.6 23.5 14.0 17.8 8.3 23.7 31.9 11.9 12.7 POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320883 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 27.1;Oligodendrocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" 5.8 12.4 13.2 4.1 14.9 2.5 5.7 13.5 13.4 8.0 12.5 6.7 2.6 6.7 9.8 5.5 5.8 4.0 7.9 12.7 13.1 10.8 9.3 5.6 1.8 14.6 14.6 6.1 8.8 8.6 12.6 7.0 13.4 7.8 3.3 5.6 6.3 6.9 19.1 4.7 4.9 4.6 13.7 5.6 5.9 37.5 14.4 2.9 10.9 8.4 1.9 7.9 5.3 15.4 15.6 19.4 18.6 21.1 13.0 10.3 14.8 13.4 10.8 19.3 16.6 9.6 13.6 4.6 10.6 12.6 27.1 17.1 8.8 13.3 13.5 6.9 12.1 2.8 8.9 7.9 15.8 3.2 8.9 10.5 13.9 18.3 17.8 13.6 11.5 4.5 7.4 10.5 13.0 30.7 5.4 15.0 5.3 21.4 16.2 5.3 18.0 4.1 20.4 11.3 15.6 15.2 8.7 14.6 11.3 12.0 15.1 6.5 9.6 14.6 22.8 17.1 12.0 6.8 14.5 2.1 7.4 4.8 13.2 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 13.2 14.9 13.5 13.4 12.7 13.1 14.6 14.6 13.4 13.7 14.4 15.4 3.2 6.4 2.8 27.1 2.0 3.1 2.7 3.4 2.8 7.5 7.2 7.6 4.3 4.3 1.6 1.8 16.7 6.0 1.2 6.5 0.0 7.6 14.3 5.8 6.7 3.1 18.0 0.0 12.9 7.5 10.2 6.1 4.1 7.0 2.5 6.4 2.5 5.7 5.5 8.4 14.5 3.2 2.0 2.2 2.6 17.2 1.8 2.4 1.8 9.4 2.3 5.9 0.0 20.1 30.5 5.5 3.2 4.1 2.1 5.2 2.5 3.6 5.1 15.1 0.0 6.2 5.0 11.3 8.2 5.2 1.8 5.7 1.2 13.9 3.6 1.9 POPDC3 "bA355M14.1, MGC22671, POP3" ENSG00000132429 "Popeye domain containing 3" Q9HBV1 6 105157900-105180014 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;skeletal muscle: 96.3;tongue: 29.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 42.8;Early spermatids: 88.0;Excitatory neurons: 16.6;Late spermatids: 18.2;Oligodendrocytes: 15.0;Skeletal myocytes: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 25.9;RH-30: 15.8;SH-SY5Y: 15.4;U-87 MG: 14.2;WM-115: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012514 Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" "HPA012514: " "unprognostic (2.17e-1)" "unprognostic (2.15e-2)" "unprognostic (3.65e-1)" "unprognostic (1.14e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.79e-4)" "unprognostic (2.81e-1)" "unprognostic (1.69e-1)" "unprognostic (5.12e-3)" "unprognostic (2.37e-1)" "unprognostic (2.83e-9)" "unprognostic (6.25e-2)" "unprognostic (1.24e-1)" "unprognostic (3.75e-3)" "unprognostic (1.33e-2)" 0.5 0.3 5.1 0.3 6.8 0.0 0.2 5.8 10.0 0.5 4.8 2.5 0.1 0.9 1.5 1.8 0.4 0.7 23.0 6.2 6.2 0.2 0.0 0.1 0.1 6.3 6.4 0.2 0.1 0.1 4.4 0.7 6.2 0.8 0.0 0.5 1.3 0.3 96.3 0.2 0.5 0.0 6.3 0.0 3.2 3.9 6.0 0.0 0.2 29.6 0.0 1.3 0.4 9.7 1.3 1.6 0.5 0.2 2.7 6.8 0.6 2.9 2.5 4.5 5.2 0.0 1.6 0.1 1.1 5.5 25.9 0.0 1.7 1.5 3.6 0.0 4.1 0.0 1.1 0.0 0.1 0.0 0.0 2.3 0.3 7.5 1.0 1.4 0.3 0.1 3.4 7.0 12.8 0.0 0.0 1.5 3.0 0.0 6.3 0.5 15.8 0.0 0.0 0.0 7.5 15.4 0.0 0.1 11.5 1.4 0.0 6.2 6.5 3.4 0.0 2.1 10.7 0.0 0.0 0.0 14.2 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.8 5.8 10.0 6.2 6.2 6.3 6.4 6.2 6.3 6.0 9.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 42.8 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 88.0 1.5 1.0 0.4 0.0 0.0 16.6 0.0 1.2 2.0 0.0 5.6 0.0 0.1 0.0 0.0 0.3 0.0 4.9 0.0 2.0 0.0 0.0 18.2 0.6 0.7 0.0 2.8 2.0 0.0 0.0 0.5 15.0 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 32.0 3.5 2.9 5.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508962-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 37.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.5;Club cells: 44.2;Pancreatic endocrine cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 176.9;LHCN-M2: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" 5.2 37.3 8.7 3.3 8.3 2.9 4.7 7.0 10.6 9.1 4.5 6.3 2.3 7.1 2.1 10.8 5.8 4.6 11.5 11.2 7.0 3.7 1.5 4.6 3.6 7.1 6.6 4.3 3.5 9.8 4.7 2.4 7.2 4.5 1.6 7.4 4.9 11.6 7.6 5.9 3.7 4.6 6.2 4.5 5.2 5.1 7.7 2.3 6.3 3.5 3.3 6.2 7.1 7.8 13.1 15.6 3.8 26.6 15.9 9.4 1.6 3.7 7.7 5.8 3.9 1.8 19.7 1.1 15.9 8.3 6.5 17.3 5.5 176.9 1.8 8.3 1.8 2.2 9.0 3.8 23.4 2.0 22.5 12.2 20.6 16.8 36.0 13.5 5.3 6.4 1.0 12.1 60.8 3.7 2.0 2.8 4.9 4.0 10.4 4.0 4.6 20.5 9.8 5.1 4.2 6.5 30.8 5.9 5.9 2.5 6.7 1.0 3.3 15.0 7.8 36.4 6.8 10.4 6.3 1.5 43.0 4.9 8.7 16.9 5.5 6.8 10.8 4.9 8.5 3.2 7.1 9.0 6.8 3.5 4.7 7.1 1.1 8.4 4.3 3.6 4.9 4.7 8.7 8.3 7.0 10.6 11.2 7.0 7.1 6.6 7.2 6.2 7.7 7.8 5.4 6.4 2.8 5.2 3.8 4.0 5.3 68.5 8.0 15.4 2.9 4.6 3.4 4.3 44.2 16.5 18.8 0.3 7.3 0.8 1.9 6.9 0.2 13.4 3.5 5.7 6.0 1.3 7.8 9.9 1.3 5.0 3.6 17.8 5.7 3.9 5.0 0.7 3.5 8.4 7.6 2.9 12.2 2.7 4.5 0.1 5.6 2.5 3.6 2.8 3.1 10.1 10.3 6.0 2.8 36.4 1.8 4.1 6.3 2.5 0.2 0.7 8.7 15.5 6.6 4.0 4.8 2.9 4.9 4.2 3.8 8.2 6.9 7.5 1.5 6.6 PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 369.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA013582: AB_1855694, HPA014133: AB_1855695" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.96e-3)" "unprognostic (1.44e-1)" "unprognostic (9.89e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.33e-3)" "unprognostic (5.13e-2)" "unprognostic (4.14e-2)" "unprognostic (5.25e-2)" "unprognostic (1.28e-2)" 45.2 46.0 40.0 28.6 41.4 16.5 39.5 41.5 47.9 38.7 37.3 34.0 27.7 57.3 104.8 41.0 46.1 25.9 62.5 42.0 42.6 49.0 137.2 33.4 33.3 44.2 41.4 49.9 73.9 30.8 42.8 22.6 41.4 42.7 27.7 16.7 60.0 34.6 134.5 29.6 36.0 40.7 41.8 51.5 42.5 35.1 42.1 31.0 30.3 112.0 38.3 34.9 32.3 42.6 63.5 62.2 35.4 56.5 84.8 30.2 65.8 44.6 46.5 63.5 44.4 59.1 38.7 78.3 45.9 44.5 68.7 35.3 70.3 56.3 41.3 58.7 63.2 64.2 30.7 128.3 111.1 74.3 58.2 28.8 67.5 60.2 68.2 34.2 44.7 61.4 48.0 68.3 57.6 73.4 69.2 56.5 37.2 81.5 64.8 63.9 70.9 369.2 46.9 33.2 79.8 42.8 42.8 88.3 65.7 36.1 39.4 125.3 25.0 33.9 48.7 29.8 51.0 150.5 67.9 95.1 56.4 83.4 65.4 73.7 61.0 103.3 50.4 52.2 53.7 44.5 42.1 50.2 62.5 43.9 40.1 41.7 25.4 65.0 55.8 74.1 50.9 63.9 40.0 41.4 41.5 47.9 42.0 42.6 44.2 41.4 41.4 41.8 42.1 42.6 9.7 16.0 12.7 5.5 33.5 18.0 9.8 14.3 9.1 12.2 21.8 19.0 14.2 20.0 10.6 20.2 12.5 45.3 22.8 17.3 35.2 29.8 5.9 5.8 14.7 10.8 8.4 30.7 7.4 35.1 60.3 18.2 28.1 11.9 23.6 13.1 16.1 36.1 38.0 6.7 7.7 28.5 20.3 19.8 16.3 9.1 23.6 17.9 19.6 8.4 16.6 25.3 24.7 9.5 9.1 30.9 20.4 44.8 101.5 18.4 30.0 29.2 3.8 10.9 32.9 10.2 21.0 32.1 44.8 18.7 17.3 77.4 22.6 16.2 22.3 12.9 PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 40.1;ovary: 11.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.5;Cardiomyocytes: 125.5;Granulosa cells: 181.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 38.4;cerebral cortex: 40.1;hippocampal formation: 37.0;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.0;SK-MEL-30: 1.6;U-2 OS: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "HPA055149: AB_2682717, HPA059099: AB_2732632" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (2.10e-3)" "unprognostic (3.87e-3)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (5.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (8.08e-5)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" 1.6 2.2 38.4 0.3 6.4 0.0 2.0 0.0 40.1 2.7 0.0 2.9 0.6 2.3 0.0 1.5 3.6 0.1 1.6 37.0 4.8 3.1 0.9 1.3 0.1 3.4 2.1 11.9 0.6 0.3 5.6 0.2 2.2 3.1 0.0 1.3 0.9 0.6 0.4 2.0 1.8 0.0 0.0 0.9 2.0 1.3 6.5 0.0 1.9 0.0 0.0 2.4 2.4 17.5 0.0 0.1 0.0 0.5 0.2 0.1 0.2 0.8 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.8 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.4 6.4 0.0 40.1 37.0 4.8 3.4 2.1 2.2 0.0 6.5 17.5 3.2 0.0 0.0 4.9 0.5 4.0 8.0 3.4 14.8 67.5 1.8 3.0 125.5 10.0 1.2 1.8 10.4 6.7 1.7 2.2 1.9 0.1 1.3 1.3 2.3 6.7 9.0 4.2 12.6 0.0 1.0 7.8 4.6 0.5 0.0 181.6 5.0 3.5 1.0 32.0 10.9 5.5 0.0 0.8 2.1 1.2 6.2 1.9 3.6 6.5 0.2 16.0 1.0 3.5 5.0 0.2 3.4 6.4 0.8 3.6 5.5 0.1 3.7 8.7 0.0 3.6 8.0 0.8 1.6 3.8 2.7 3.6 2.2 8.1 4.1 4.8 PRRT1B "DSPD2, IFITMD8" ENSG00000283526 "Proline rich transmembrane protein 1B" A0A1B0GWB2 9 131545514-131558620 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 6.4;lung: 4.1;pancreas: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A549: 14.7;BEWO: 9.6;MCF7: 3.9;T-47d: 7.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" 0.0 0.0 0.2 0.0 0.9 0.0 0.2 0.6 0.5 0.5 0.1 1.4 0.4 0.2 0.0 0.0 6.4 0.7 0.0 0.1 0.1 0.5 2.9 4.1 0.0 0.2 0.2 0.0 4.2 1.5 0.1 0.0 0.1 2.5 1.6 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.7 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.1 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 395.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 25.1 22.6 44.3 26.5 80.7 39.6 28.2 62.4 56.0 28.1 48.9 49.5 50.2 25.3 26.9 35.2 22.9 31.7 18.0 47.4 51.6 35.5 31.9 32.1 22.4 73.0 63.8 22.0 22.9 35.1 11.6 43.1 71.5 24.3 46.3 23.4 22.9 23.4 18.4 38.2 49.0 27.1 55.7 22.6 31.0 32.5 60.8 26.2 36.9 23.3 30.7 35.0 19.2 119.1 37.1 55.9 50.6 20.0 68.9 49.9 46.7 52.5 60.1 52.6 66.7 69.9 88.9 23.7 34.1 50.5 43.0 94.9 43.2 40.1 57.3 54.6 26.7 27.1 35.1 34.4 63.8 27.7 50.7 50.4 71.9 44.3 54.4 48.5 43.2 26.2 31.0 46.6 50.0 72.8 21.0 35.7 22.0 64.5 40.4 26.4 42.7 30.2 73.7 76.5 28.1 38.3 57.4 53.0 47.1 45.4 66.3 60.7 45.7 53.1 43.5 44.1 25.3 30.3 47.9 23.7 44.9 32.8 33.3 126.8 94.5 96.3 23.1 106.0 22.6 23.1 22.3 19.0 83.4 31.8 20.7 20.1 129.3 42.8 125.0 43.6 37.0 70.3 44.3 80.7 62.4 56.0 47.4 51.6 73.0 63.8 71.5 55.7 60.8 119.1 22.2 28.9 30.5 35.9 25.8 28.6 24.6 24.7 12.0 17.1 25.0 17.7 12.5 15.7 30.2 23.9 39.6 27.1 30.7 79.1 5.9 27.1 22.9 26.3 26.4 22.3 16.2 12.0 38.9 26.7 29.2 23.7 32.1 47.4 18.3 29.6 15.7 24.6 30.5 13.5 40.2 39.5 24.4 50.5 40.8 12.9 16.4 52.3 16.0 39.4 51.8 13.8 14.4 48.7 395.8 38.2 58.8 15.4 23.6 38.8 76.2 13.0 29.0 28.0 26.3 20.0 19.0 40.2 14.4 20.4 33.0 49.9 21.6 18.6 41.3 51.5 PSENEN PEN2 ENSG00000205155 "Presenilin enhancer, gamma-secretase subunit" Q9NZ42 19 35745600-35747519 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 573.3;Respiratory ciliated cells: 954.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA047435 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA047435: AB_2680047" "unprognostic (1.96e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.64e-1)" "unprognostic (2.01e-1)" "unprognostic (2.79e-1)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "unprognostic (1.41e-1)" "unprognostic (3.51e-3)" "unprognostic (2.30e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.70e-4)" "unprognostic (6.85e-2)" "unprognostic (1.80e-1)" "unprognostic (2.10e-1)" "unprognostic (5.41e-3)" 50.4 65.7 87.8 39.0 86.9 35.6 54.2 91.0 89.6 59.4 127.3 57.3 42.0 46.5 134.6 69.5 228.0 37.8 55.2 88.5 96.1 76.5 78.4 54.9 41.2 95.5 103.8 37.5 63.0 75.1 60.0 36.4 100.2 46.7 63.4 38.5 55.6 53.3 51.9 45.4 43.1 47.7 96.0 57.6 52.2 148.9 89.3 54.0 58.4 46.7 61.7 59.3 44.6 97.5 94.2 187.8 75.1 87.2 136.5 85.3 43.2 49.8 108.9 111.0 117.7 52.3 173.7 48.9 116.0 99.4 76.2 54.6 65.3 86.1 105.0 81.8 55.1 34.5 44.1 50.6 118.9 53.7 60.5 88.8 153.4 129.7 106.2 95.8 112.2 94.1 53.7 116.5 127.8 108.5 62.8 63.7 55.9 214.9 49.7 58.8 30.2 89.9 226.4 46.7 62.1 94.5 65.6 144.3 45.6 98.8 92.0 119.7 46.4 88.4 52.9 60.3 81.1 88.0 107.6 62.1 152.0 50.3 72.1 140.8 208.3 202.0 131.3 232.9 123.9 109.3 95.8 114.0 154.8 100.4 73.1 92.9 539.2 91.4 191.1 337.1 107.4 245.3 87.8 86.9 91.0 89.6 88.5 96.1 95.5 103.8 100.2 96.0 89.3 97.5 58.4 38.5 38.2 4.2 53.5 38.7 59.3 192.5 39.3 13.2 55.6 36.7 29.7 51.5 137.6 128.8 14.6 92.5 73.2 132.8 60.7 146.8 199.1 573.3 42.7 52.4 70.2 36.6 1.9 151.0 135.9 50.5 34.1 75.6 57.7 22.5 42.1 49.7 164.4 6.7 2.1 66.1 185.1 51.2 90.9 126.5 54.7 69.8 71.2 1.9 85.9 58.6 86.5 2.0 6.3 171.4 152.5 40.6 83.1 44.2 122.4 194.4 954.0 19.7 52.6 33.9 147.7 344.8 35.8 48.4 48.4 104.1 53.3 56.3 67.3 74.0 PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" 37.3 38.2 21.9 31.7 26.1 20.1 29.0 21.9 33.7 26.3 20.9 34.8 35.5 37.4 25.6 41.5 24.3 20.3 51.3 27.5 28.5 34.1 42.1 27.0 28.8 26.9 24.9 19.2 17.3 72.7 32.9 36.8 28.3 29.7 36.8 25.4 25.8 33.4 136.3 34.9 29.3 44.9 24.5 25.2 27.9 29.0 24.5 36.6 27.4 81.6 38.3 37.3 27.8 24.4 103.9 113.1 120.6 93.8 122.2 88.7 115.4 135.3 139.4 133.4 134.0 136.5 97.6 80.0 123.3 150.5 138.0 95.0 169.4 125.0 174.3 124.3 93.3 148.7 81.6 155.5 62.9 133.3 119.4 76.5 57.8 142.4 73.9 73.4 159.6 70.3 212.1 56.8 158.7 100.3 103.0 68.3 157.8 100.1 89.3 86.0 190.4 77.7 96.5 104.0 78.8 74.1 108.7 94.1 65.7 120.6 75.3 74.7 152.3 101.4 110.8 126.0 129.8 48.6 80.2 140.4 162.7 100.0 123.4 34.6 27.8 18.8 25.1 39.0 27.3 21.0 25.8 23.8 30.9 17.2 19.2 22.9 12.5 35.9 42.5 18.9 32.3 25.7 21.9 26.1 21.9 33.7 27.5 28.5 26.9 24.9 28.3 24.5 24.5 24.4 51.9 51.3 48.5 77.7 32.9 33.1 37.7 57.0 19.9 46.4 23.0 25.8 125.4 31.5 53.0 33.1 41.7 119.2 27.0 63.6 17.6 83.9 6.2 51.2 67.5 51.7 39.4 61.6 100.0 102.2 101.4 54.6 42.3 60.9 103.9 67.8 30.0 86.9 72.3 90.9 96.0 30.0 57.0 44.2 23.5 9.9 34.8 49.8 17.8 54.4 62.6 46.6 29.9 67.3 93.1 98.6 26.2 45.9 49.4 46.5 46.9 32.1 66.9 53.2 72.3 54.6 128.2 247.9 158.8 39.2 33.1 167.5 36.6 65.5 42.9 38.8 PTCRA "PT-ALPHA, PTA" ENSG00000171611 "Pre T cell antigen receptor alpha" Q6ISU1 6 42915989-42925838 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "lymphoid tissue: 128.6" "Group enriched" "Detected in some" 6 "dendritic cells: 110.6;Macrophages: 152.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 410.7" "Lineage enriched" "Detected in many" 46 "dendritic cells: 410.7" "Group enriched" "Detected in some" 9 "MOLT-4: 42.8;SK-MEL-30: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (5.50e-2)" "unprognostic (3.37e-2)" "unprognostic (2.77e-1)" "unprognostic (1.64e-1)" "unprognostic (2.83e-2)" "unprognostic (6.57e-4)" "unprognostic (7.18e-2)" "unprognostic (4.24e-2)" "unprognostic (8.16e-2)" "unprognostic (1.11e-2)" "unprognostic (2.73e-1)" "unprognostic (2.84e-4)" "unprognostic (1.16e-1)" "unprognostic (4.89e-1)" "unprognostic (3.22e-2)" "unprognostic (3.09e-2)" "unprognostic (1.45e-1)" 0.3 0.1 0.0 0.3 0.7 1.7 0.1 0.1 1.3 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.2 2.6 2.8 1.1 0.7 0.0 0.0 0.0 0.0 0.6 0.8 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 5.0 0.1 0.0 3.3 128.6 0.1 0.0 2.2 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 8.7 0.4 1.7 0.1 1.1 0.1 0.0 0.0 0.3 0.4 0.1 0.4 0.0 8.9 0.1 0.7 410.7 0.0 32.8 0.0 0.7 0.1 1.3 0.3 0.4 1.1 0.7 0.8 0.4 3.3 1.8 0.1 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 110.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 6.5 0.1 0.0 0.0 0.0 0.0 2.2 0.0 19.4 0.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 152.8 5.4 0.0 2.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 PTGER2 EP2 ENSG00000125384 "Prostaglandin E receptor 2" P43116 14 52314305-52328598 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.4" "Cell type enhanced" "Detected in many" "dendritic cells: 55.6;Macrophages: 33.2;NK-cells: 177.1;T-cells: 63.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 26.1;ASC TERT1: 68.3;HHSteC: 43.8;HL-60: 25.2;HSkMC: 56.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.48e-1)" "unprognostic (2.48e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (1.55e-2)" "unprognostic (3.24e-1)" "unprognostic (3.11e-3)" "unprognostic (1.79e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-3)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (8.48e-3)" "unprognostic (5.26e-3)" "unprognostic (6.71e-2)" "unprognostic (5.74e-2)" 8.7 1.4 0.1 12.6 0.6 38.4 3.6 0.0 0.4 17.2 3.0 8.0 6.2 9.4 0.6 1.8 4.6 9.7 1.1 0.1 0.2 3.2 3.6 5.4 4.5 0.7 0.5 8.2 1.2 0.4 0.7 14.4 0.3 9.9 6.6 0.0 3.2 2.8 0.7 1.3 9.4 5.1 0.6 11.8 17.5 2.9 0.3 3.2 1.7 0.3 1.7 5.8 2.2 0.3 1.3 0.5 0.0 0.0 26.1 68.3 0.1 2.1 0.4 2.3 2.8 0.0 0.1 0.0 1.8 1.4 0.0 9.3 0.0 0.5 3.3 0.0 13.2 0.0 0.7 0.0 43.8 25.2 0.3 56.2 1.1 5.8 0.9 7.4 0.0 0.0 0.0 0.0 13.4 1.2 0.0 1.0 1.0 4.5 8.8 0.2 0.0 0.0 20.6 0.1 0.7 20.6 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.9 1.5 15.5 0.0 0.0 0.0 0.0 6.1 14.2 0.2 5.8 35.9 35.5 106.7 30.6 129.3 0.2 91.0 114.3 19.0 0.1 21.7 67.7 4.7 73.5 61.5 0.9 50.0 66.3 0.1 0.6 0.0 0.4 0.1 0.2 0.7 0.5 0.3 0.6 0.3 0.3 4.0 3.2 1.7 0.0 3.2 1.8 0.4 0.8 1.2 0.0 2.0 2.5 1.2 1.5 0.7 3.7 0.0 0.1 55.6 0.7 0.0 0.3 0.0 24.0 1.6 0.9 6.0 3.0 0.1 0.0 0.3 13.9 15.3 7.7 20.8 2.9 4.2 0.6 10.0 0.0 0.1 6.0 0.0 28.0 19.6 0.5 4.1 33.2 3.6 0.0 16.6 0.0 177.1 0.0 0.0 1.5 0.1 3.0 3.7 1.4 0.0 0.3 9.6 0.0 0.0 1.3 11.6 0.1 1.2 0.2 1.6 0.3 63.1 0.2 0.6 0.2 PTGIR IP ENSG00000160013 "Prostaglandin I2 receptor" P43119 19 46620468-46625089 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.5" "Group enriched" "Detected in some" 5 "Langerhans cells: 177.2;monocytes: 160.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "classical monocyte: 28.2;intermediate monocyte: 65.3;myeloid DC: 20.9;non-classical monocyte: 38.7" "Group enriched" "Detected in many" 11 "dendritic cells: 20.9;monocytes: 65.3" "Cell line enhanced" "Detected in some" "BJ: 10.8;BJ hTERT+: 12.2;fHDF/TERT166: 15.4;HDLM-2: 7.6;HEL: 28.3;HHSteC: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (3.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-1)" "unprognostic (3.49e-3)" "unprognostic (4.22e-2)" "unprognostic (6.09e-2)" "unprognostic (2.12e-1)" "unprognostic (7.45e-2)" "unprognostic (4.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.09e-8)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.16e-1)" "unprognostic (5.66e-2)" 13.7 6.8 0.5 6.0 0.4 3.4 5.2 0.4 0.9 6.0 0.4 4.8 2.0 4.6 0.3 2.1 4.5 2.9 27.3 0.6 0.4 26.1 9.2 55.5 3.5 0.6 0.5 2.4 5.7 0.6 1.9 4.4 0.5 2.6 1.0 0.0 4.1 0.9 2.8 4.3 5.8 2.9 0.6 10.8 6.7 0.3 0.5 1.5 16.6 0.8 2.6 6.0 5.2 0.5 0.0 0.0 0.0 0.0 0.2 5.5 0.0 10.8 12.2 1.5 4.3 0.0 0.0 0.0 0.9 15.4 0.1 0.0 0.0 0.0 0.9 7.6 0.0 28.3 0.0 0.0 7.2 0.0 0.0 1.7 0.0 3.9 0.2 0.0 3.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.5 1.4 1.7 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.7 0.7 0.0 28.2 0.0 0.0 65.3 0.4 1.5 0.3 0.0 20.9 0.7 3.3 0.1 1.1 0.0 38.7 2.0 3.9 17.6 0.5 0.4 0.4 0.9 0.6 0.4 0.6 0.5 0.5 0.6 0.5 0.5 1.5 0.0 0.6 0.3 3.7 4.2 0.8 0.4 0.0 0.4 0.2 0.5 0.9 0.0 0.1 1.8 0.0 0.1 2.7 0.2 0.0 0.3 0.2 0.1 1.5 2.3 0.0 0.4 0.7 0.4 0.1 10.3 0.5 0.1 3.8 0.1 4.2 0.2 2.6 0.0 0.6 0.0 0.0 7.9 177.2 0.0 2.1 23.7 7.2 0.0 160.9 0.1 1.0 0.5 0.3 0.4 0.0 0.0 0.1 0.8 0.0 0.2 0.7 0.8 6.6 1.1 30.9 0.1 0.4 0.0 4.4 0.3 2.0 0.1 0.0 0.7 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 161.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 59.0;Inhibitory neurons: 51.9" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 161.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.1;NTERA-2: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: AB_2686487" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 1.5 0.5 37.2 0.2 161.0 0.1 1.1 0.0 55.2 0.7 0.0 1.0 0.1 0.8 0.0 0.5 1.1 0.3 11.9 32.1 25.5 1.7 0.0 1.5 0.1 11.3 6.4 2.1 0.4 0.2 2.1 0.0 6.7 1.0 0.3 2.0 1.2 0.6 0.7 0.6 0.6 0.4 4.7 0.4 0.9 2.9 19.9 0.0 0.7 3.3 0.0 1.0 1.1 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 161.0 0.0 55.2 32.1 25.5 11.3 6.4 6.7 4.7 19.9 29.5 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.2 6.9 0.0 0.0 59.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 51.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.3 0.0 12.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 2.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 73.6;Late spermatids: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 42.3;SK-BR-3: 75.8;T-47d: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Peroxisomes "Nucleoli fibrillar center" "HPA050077: AB_2681006" "unprognostic (3.41e-2)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (5.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-1)" "prognostic favorable (3.88e-4)" "unprognostic (3.53e-1)" "unprognostic (4.47e-2)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.03e-10)" "unprognostic (3.84e-2)" "unprognostic (2.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.20e-1)" 4.1 11.2 5.1 3.0 5.2 3.2 11.9 3.8 5.6 5.6 4.3 6.2 8.2 4.1 5.1 6.3 6.0 3.3 6.4 5.0 4.0 4.9 8.9 13.9 3.6 4.6 4.5 6.8 6.8 14.7 3.5 3.2 4.1 8.7 5.7 4.4 15.2 6.4 8.0 11.1 7.4 5.1 4.2 4.6 6.8 2.5 5.3 3.5 11.5 6.9 3.9 5.4 5.8 6.5 2.8 12.1 3.3 11.9 5.7 8.3 8.5 8.7 4.7 6.6 2.9 42.3 13.2 0.1 16.2 7.3 16.1 12.5 9.0 10.1 4.7 3.7 3.4 14.0 9.7 0.1 5.3 0.7 10.3 6.4 10.8 9.0 3.0 3.3 4.3 4.4 7.9 8.6 4.7 26.4 12.9 9.8 0.3 21.7 0.0 6.8 16.3 1.7 4.2 9.0 10.7 5.4 24.2 75.8 7.9 1.9 64.0 4.7 8.2 4.7 5.4 11.9 8.2 5.5 13.2 0.2 9.0 4.6 8.1 2.2 11.1 17.5 10.8 22.2 11.3 7.6 10.9 10.9 8.8 9.9 8.3 11.2 2.9 9.1 34.2 5.3 8.5 8.6 5.1 5.2 3.8 5.6 5.0 4.0 4.6 4.5 4.1 4.2 5.3 6.5 5.2 19.2 73.6 7.2 5.5 1.7 4.3 9.4 4.0 11.1 16.8 12.3 12.6 7.2 17.8 18.4 14.6 12.9 3.5 14.2 9.8 8.2 28.7 6.3 6.1 7.6 4.2 9.9 6.4 9.9 24.3 8.5 6.6 5.7 3.8 6.7 8.9 36.0 15.1 5.0 5.7 10.8 6.1 7.5 1.6 44.0 10.5 6.2 3.6 6.5 7.5 13.6 9.2 9.0 10.8 8.5 10.3 11.3 7.0 4.5 23.0 11.2 7.8 11.4 6.6 8.8 7.8 4.6 9.8 9.5 2.4 4.4 5.8 16.9 13.0 4.0 RABAC1 "PRA1, PRAF1, YIP3" ENSG00000105404 "Rab acceptor 1" Q9UI14 19 41956681-41959321 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019320, HPA029171" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB019320: , HPA029171: AB_10602121" "unprognostic (7.70e-2)" "unprognostic (5.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.93e-1)" "unprognostic (3.41e-2)" "unprognostic (1.19e-2)" "unprognostic (3.32e-3)" "unprognostic (9.69e-2)" "unprognostic (1.76e-1)" "unprognostic (8.92e-2)" "unprognostic (2.31e-1)" "unprognostic (6.97e-2)" "unprognostic (7.45e-2)" 180.4 163.6 128.4 61.1 129.5 53.2 170.4 136.7 177.5 213.4 137.5 192.0 75.3 234.5 28.2 115.9 174.2 37.9 166.5 122.3 149.5 181.7 198.9 180.7 51.9 151.7 135.4 184.3 177.9 68.7 242.4 55.4 149.1 160.4 28.4 14.6 197.2 57.9 125.9 146.7 148.9 49.0 136.7 166.0 189.9 155.4 144.5 34.0 171.4 38.0 31.3 168.6 171.4 147.7 95.7 261.0 35.5 94.6 234.8 136.7 47.7 278.8 144.9 67.3 93.8 46.8 60.6 277.0 140.4 161.9 39.1 70.0 21.9 89.0 25.5 102.1 151.6 40.4 73.0 82.1 130.8 35.5 106.7 137.5 86.5 45.5 31.0 84.4 94.2 76.0 17.9 346.6 61.0 149.2 62.6 32.0 44.4 136.8 167.6 83.3 77.4 54.4 65.0 71.8 67.0 97.4 73.5 157.3 71.3 26.2 59.1 29.4 187.2 119.3 77.4 116.2 40.4 303.8 111.0 96.1 172.3 66.3 131.3 720.0 389.3 551.7 372.2 217.3 313.6 398.7 331.0 325.0 232.5 339.4 222.3 298.8 774.6 253.4 220.1 410.2 403.4 511.2 128.4 129.5 136.7 177.5 122.3 149.5 151.7 135.4 149.1 136.7 144.5 147.7 333.1 128.2 109.8 19.2 203.4 124.7 160.1 242.1 119.5 62.6 173.6 232.3 59.9 163.0 162.3 182.1 16.7 187.5 173.6 411.2 137.0 339.7 203.1 91.9 247.0 234.4 195.0 35.1 14.8 301.4 467.1 309.7 138.6 143.8 142.7 163.5 241.3 237.7 174.0 57.2 18.8 507.5 246.2 119.8 187.0 658.2 307.0 133.1 405.6 21.5 230.8 168.4 161.7 21.1 43.1 427.9 371.7 251.3 625.9 222.3 358.3 326.7 154.8 69.2 230.1 129.4 337.8 234.3 136.1 89.7 136.4 271.7 188.7 176.1 247.4 223.3 RABGAP1 "GAPCenA, TBC1D11" ENSG00000011454 "RAB GTPase activating protein 1" Q9Y3P9 9 122940833-123104866 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.1;Oligodendrocytes: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064860, HPA072273" Enhanced Enhanced Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA064860: AB_2685372, HPA072273: AB_2686504" "prognostic unfavorable (8.09e-4)" "unprognostic (3.45e-1)" "unprognostic (3.85e-3)" "unprognostic (3.90e-1)" "unprognostic (4.16e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (3.75e-2)" "unprognostic (5.19e-2)" "unprognostic (3.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.06e-6)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (8.72e-2)" "unprognostic (3.05e-2)" 22.5 15.5 27.3 16.9 28.8 7.3 21.6 23.8 31.6 21.9 19.4 39.7 12.2 28.8 25.4 31.7 21.9 19.0 26.3 28.0 27.8 19.9 11.7 19.3 19.5 27.3 29.8 23.8 16.3 31.3 16.8 21.4 28.0 29.4 22.7 24.9 24.3 30.2 34.5 23.6 17.2 31.7 26.1 18.4 21.6 21.8 27.1 19.6 39.2 30.7 19.4 26.0 21.8 30.2 19.5 25.7 39.6 33.0 44.8 36.2 24.5 20.0 35.8 30.3 28.2 29.9 18.6 26.6 15.6 31.3 40.4 64.7 25.6 25.0 32.4 25.1 15.4 20.8 40.4 22.9 38.3 17.2 17.5 35.2 37.6 26.1 29.3 43.5 34.8 26.2 18.3 19.9 36.9 43.3 22.5 13.5 14.6 55.7 19.6 36.7 72.3 23.0 25.2 21.3 22.3 17.2 35.7 31.9 18.6 29.5 60.7 9.4 26.9 25.6 15.1 28.3 20.3 19.3 33.9 27.7 24.0 8.7 22.9 3.4 1.3 1.8 0.9 2.1 0.7 1.1 0.9 0.9 1.1 1.4 1.6 1.1 2.1 0.8 1.0 1.5 1.2 0.5 27.3 28.8 23.8 31.6 28.0 27.8 27.3 29.8 28.0 26.1 27.1 30.2 47.2 25.6 50.8 115.2 26.6 18.0 23.0 20.8 40.5 44.9 26.7 26.4 46.9 11.5 31.9 11.0 50.1 25.5 26.0 24.9 3.9 11.8 15.4 31.5 30.3 33.1 16.9 17.0 179.1 14.5 8.7 22.9 18.3 47.7 14.0 34.2 27.1 15.4 15.9 57.2 129.7 16.7 24.4 28.6 14.4 17.5 40.7 25.1 14.2 78.7 35.9 33.6 33.0 101.0 147.7 13.0 18.6 51.6 11.9 39.7 11.7 10.1 30.6 34.6 85.5 31.0 51.4 73.8 37.4 27.6 17.3 41.6 16.4 22.5 21.6 27.8 RABGAP1L "FLJ38519, HHL, KIAA0471, TBC1D18" ENSG00000152061 "RAB GTPase activating protein 1 like" "B7ZAP0, Q5R372" 1 174159410-174995308 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 121.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 551.4;Inhibitory neurons: 444.0;Microglial cells: 267.0;Oligodendrocyte precursor cells: 362.4;Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 136.9;Karpas-707: 87.6;U-698: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054695 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054695: AB_2682577" "unprognostic (2.57e-2)" "unprognostic (7.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.89e-3)" "unprognostic (1.54e-2)" "unprognostic (6.96e-3)" "unprognostic (8.55e-2)" "prognostic favorable (1.16e-4)" "unprognostic (2.66e-2)" "unprognostic (3.51e-2)" "unprognostic (2.66e-2)" "unprognostic (1.98e-1)" "unprognostic (9.14e-3)" "unprognostic (6.69e-2)" "unprognostic (2.14e-1)" "unprognostic (5.03e-2)" "unprognostic (2.46e-1)" 12.1 8.6 16.1 22.8 19.1 31.1 15.7 46.1 20.6 15.0 51.2 20.4 22.0 13.1 16.3 18.6 19.0 22.1 121.0 19.4 17.2 16.8 16.3 26.4 41.9 9.6 13.2 28.8 19.9 10.5 20.5 18.3 11.2 10.4 21.2 16.2 23.6 10.5 6.5 16.5 24.3 13.4 10.0 26.3 22.6 31.1 15.9 20.1 10.0 7.4 50.1 19.9 10.3 19.5 15.6 8.0 6.0 6.2 16.4 23.9 13.3 18.1 16.0 7.9 10.6 7.5 56.0 136.9 12.5 14.0 9.3 19.6 5.2 12.1 11.0 37.7 8.5 34.2 11.0 11.5 10.1 15.1 13.2 18.9 8.2 5.7 8.5 13.3 17.7 12.6 20.2 87.6 12.8 5.3 11.9 14.4 37.2 20.9 4.8 41.0 12.0 45.7 15.5 70.9 17.5 10.4 17.2 28.8 12.1 18.4 14.0 18.1 24.5 9.9 8.9 11.0 10.7 75.6 26.3 85.7 10.9 10.1 7.5 16.7 50.0 110.2 25.7 86.5 22.7 34.7 31.5 31.5 40.3 26.4 15.2 23.5 89.6 80.3 180.8 53.6 42.3 32.9 16.1 19.1 46.1 20.6 19.4 17.2 9.6 13.2 11.2 10.0 15.9 19.5 23.1 73.7 106.1 143.7 63.8 12.4 11.4 19.9 39.3 38.7 20.7 13.2 263.0 47.1 38.6 33.1 31.3 39.1 101.2 43.3 13.7 28.8 117.2 59.0 18.6 17.6 49.1 33.8 551.4 36.9 9.5 35.3 46.9 46.8 24.6 8.9 23.9 16.3 38.5 21.9 444.0 37.8 18.3 57.0 16.2 121.3 15.5 63.1 16.0 267.0 100.4 17.3 68.0 362.4 342.8 24.5 36.0 18.8 81.8 11.5 39.8 13.3 100.3 23.8 6.6 15.0 25.1 91.8 18.5 36.9 13.1 28.2 74.6 26.1 27.0 27.5 RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic subunit alpha 1" Q6GYQ0 14 35538352-35809304 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 394.0;Inhibitory neurons: 233.9;Oligodendrocyte precursor cells: 239.3;Oligodendrocytes: 412.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved Mitochondria,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol Mitochondria "HPA000851: AB_1078945" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (8.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-2)" "unprognostic (7.65e-2)" "unprognostic (1.17e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-2)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "prognostic favorable (9.76e-5)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" 13.5 18.5 24.0 9.0 28.1 7.1 16.0 36.0 29.0 21.6 18.3 17.6 7.7 16.5 13.8 15.8 17.9 9.4 12.8 24.2 26.3 14.4 13.0 14.1 9.6 26.6 25.5 23.9 16.3 25.5 23.4 7.4 26.2 17.5 14.5 39.4 13.0 10.5 18.4 20.1 14.7 12.6 25.9 12.0 15.8 10.6 26.4 9.7 16.3 10.9 9.0 15.9 18.3 33.6 7.4 8.7 11.0 9.6 16.4 11.4 7.0 5.2 5.4 6.7 6.0 5.2 6.4 7.2 7.2 7.1 8.8 12.0 13.4 10.2 6.2 16.1 5.1 6.7 11.0 26.3 8.4 11.4 10.4 8.6 18.3 5.8 14.1 11.0 9.5 14.2 6.7 17.9 5.9 11.8 8.5 5.4 5.0 18.2 12.9 6.9 6.7 4.6 13.8 11.9 10.2 16.7 11.0 18.9 9.6 10.6 18.0 5.3 8.7 6.5 5.0 7.6 6.5 14.6 14.4 9.3 3.0 7.3 7.2 0.0 0.2 0.0 0.7 0.3 0.9 0.5 0.7 0.9 0.3 0.3 0.4 0.7 0.0 0.7 0.3 0.4 0.8 0.1 24.0 28.1 36.0 29.0 24.2 26.3 26.6 25.5 26.2 25.9 26.4 33.6 40.2 16.0 30.9 162.6 63.9 38.1 28.3 13.9 62.0 86.1 27.7 21.5 19.4 15.7 25.2 23.9 394.0 10.9 105.8 31.0 0.0 12.8 19.5 47.0 38.5 31.4 31.1 14.9 215.3 15.8 5.5 34.6 54.0 50.8 53.4 41.6 18.5 14.8 9.2 52.2 233.9 23.3 16.2 10.0 39.9 8.7 34.2 35.4 19.6 173.3 16.8 30.5 16.5 239.3 412.8 15.9 25.9 29.0 86.3 36.0 26.6 10.4 25.2 119.1 39.5 59.0 37.8 47.0 38.0 55.9 46.2 15.2 80.7 24.0 28.7 27.1 RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 212.2;Microglial cells: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 91.5;SCLC-21H: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA042707: AB_2678124, HPA043622: AB_2678585" "unprognostic (7.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (1.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.34e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-2)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "prognostic favorable (3.77e-5)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (5.33e-2)" 16.7 6.5 4.6 6.1 6.2 20.6 15.0 10.8 7.6 9.6 5.7 12.2 10.3 8.7 3.7 8.8 10.8 11.3 7.9 4.3 4.8 10.2 27.3 25.2 6.4 6.9 8.0 7.4 17.0 13.1 14.5 17.6 7.5 13.1 12.6 13.4 15.1 5.5 34.4 16.9 10.5 7.0 2.8 7.5 18.3 10.1 13.1 8.0 21.1 21.0 5.4 12.6 8.4 9.5 7.0 4.4 9.2 4.7 5.1 3.6 10.1 1.8 2.0 2.1 3.0 3.8 9.5 3.2 6.1 3.0 10.6 7.1 9.4 8.6 4.0 16.1 4.6 11.1 2.5 6.7 1.8 14.0 6.4 3.1 6.4 3.5 1.7 3.9 13.1 14.9 2.2 6.0 3.8 4.9 5.6 18.5 3.8 22.8 3.9 7.6 6.2 4.5 7.4 91.5 51.4 4.5 6.9 5.2 6.1 8.9 3.6 13.7 3.3 3.7 3.6 2.7 2.6 3.5 2.6 1.8 3.1 9.1 5.4 4.4 1.1 3.6 0.8 0.4 1.2 1.1 0.5 0.8 0.5 0.8 1.0 1.1 4.4 2.7 1.0 1.2 1.0 0.3 4.6 6.2 10.8 7.6 4.3 4.8 6.9 8.0 7.5 2.8 13.1 9.5 90.7 6.4 42.5 212.2 9.7 10.6 10.1 25.9 6.8 47.8 13.5 7.7 9.1 41.5 27.0 14.7 27.1 10.6 14.6 24.7 1.9 23.9 28.9 61.0 16.4 80.1 24.6 10.7 87.3 24.9 4.9 7.6 51.5 123.0 8.2 97.3 67.1 47.4 12.8 52.2 122.0 20.7 40.7 18.3 10.3 7.3 1.8 13.0 8.8 145.2 18.2 8.8 10.3 122.2 111.1 19.5 21.0 6.8 4.8 20.5 20.6 12.5 43.1 13.5 13.1 16.4 9.7 12.3 11.1 15.3 16.6 11.2 14.3 19.7 30.6 25.0 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;choroid plexus: 77.8;retina: 61.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.3;Cone photoreceptor cells: 70.9;Excitatory neurons: 51.2;Horizontal cells: 48.8;Inhibitory neurons: 46.1;Muller glia cells: 29.8;Rod photoreceptor cells: 73.6" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 97.3;SCLC-21H: 40.5;SH-SY5Y: 46.1;U-87 MG: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" 4.6 9.5 106.7 2.5 102.5 0.3 3.0 93.5 155.7 3.6 77.8 18.8 1.8 7.0 1.4 4.4 3.6 2.6 24.8 110.3 110.7 1.9 0.2 0.8 0.4 134.6 109.1 4.0 2.0 1.8 54.5 0.6 136.4 8.6 2.2 61.2 1.8 8.0 16.6 2.4 4.3 12.6 77.5 0.4 7.6 6.2 130.6 1.9 1.2 5.7 0.5 8.7 4.6 104.7 0.6 7.4 27.6 97.3 3.9 10.5 0.0 8.4 3.8 11.4 12.9 5.3 1.0 0.1 1.5 10.5 0.2 0.6 26.1 5.4 8.6 3.1 23.7 0.0 1.8 12.6 9.8 0.1 0.1 3.2 0.3 6.4 0.5 19.9 2.3 27.6 0.1 6.9 3.6 4.4 2.7 1.8 17.2 0.0 0.3 9.7 2.6 0.0 2.1 0.0 40.5 46.1 2.9 0.1 7.5 7.0 2.6 0.9 0.2 6.6 6.6 6.4 15.9 18.1 12.3 0.8 36.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 106.7 102.5 93.5 155.7 110.3 110.7 134.6 109.1 136.4 77.5 130.6 104.7 17.0 0.0 0.0 18.9 0.1 0.6 1.0 1.6 2.2 47.3 0.7 3.3 9.8 0.0 0.2 1.8 70.9 0.0 0.3 0.0 0.0 0.0 1.1 0.4 0.3 5.6 4.8 0.4 51.2 0.0 0.0 3.7 0.0 0.1 0.0 1.5 0.7 0.0 0.1 48.8 46.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 0.0 2.8 0.1 29.8 0.0 19.1 5.7 0.1 0.0 2.6 1.3 0.4 3.6 0.3 0.6 73.6 0.0 7.6 2.9 0.3 9.1 0.0 0.4 0.0 0.8 0.1 0.1 0.2 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" 76.9 105.4 97.1 50.5 100.2 27.3 130.6 92.7 120.7 87.1 76.8 66.6 56.8 58.4 120.0 52.1 64.7 60.8 133.2 107.3 110.5 148.0 124.3 80.4 48.2 112.2 104.8 72.2 123.0 140.7 41.5 66.6 115.2 98.9 58.1 81.5 147.7 84.2 114.3 59.1 58.1 55.0 96.4 54.3 70.2 28.3 120.0 32.1 239.4 99.6 56.7 73.2 49.1 98.3 101.7 90.9 29.7 72.5 136.0 115.9 104.7 102.2 92.6 96.4 103.4 74.9 138.1 42.5 179.6 105.1 112.5 107.5 66.8 138.9 88.5 190.6 116.4 42.8 56.3 63.5 126.8 36.9 77.4 81.3 136.0 82.2 78.0 94.5 113.7 38.7 26.0 84.5 121.3 100.0 15.7 60.7 43.4 73.5 75.3 22.4 84.3 116.6 229.1 108.4 56.9 43.1 148.5 244.6 99.8 75.5 287.3 58.9 142.4 83.4 32.0 126.5 126.4 97.6 126.2 33.8 142.6 65.4 47.8 224.4 222.9 234.3 140.1 249.5 149.4 175.7 112.7 133.9 189.0 149.2 52.5 94.6 253.0 112.7 316.2 133.6 177.9 236.4 97.1 100.2 92.7 120.7 107.3 110.5 112.2 104.8 115.2 96.4 120.0 98.3 141.2 166.7 102.3 30.0 131.1 93.0 177.7 291.6 89.4 83.5 225.3 188.1 217.3 145.8 213.7 195.0 89.6 296.0 138.4 77.0 82.2 275.1 231.5 111.8 97.0 130.5 118.0 34.9 78.6 414.1 352.8 182.3 65.7 141.6 108.9 76.0 118.2 197.0 267.1 87.5 95.0 127.5 256.3 135.0 159.9 42.0 116.2 168.8 206.3 36.5 188.6 97.2 101.0 44.7 71.5 316.5 141.1 133.9 271.6 225.3 134.1 146.1 170.6 80.0 111.7 92.6 253.0 162.8 63.9 118.1 101.6 489.8 123.7 100.3 104.5 214.8 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RER1 ENSG00000157916 "Retention in endoplasmic reticulum sorting receptor 1" O15258 1 2391775-2405442 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037240, HPA051400" Supported Supported "Golgi apparatus" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "CAB037240: AB_2179604, HPA051400: AB_2681469" "unprognostic (2.90e-2)" "unprognostic (3.35e-2)" "unprognostic (3.17e-2)" "unprognostic (2.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.23e-8)" "unprognostic (1.01e-1)" "unprognostic (5.41e-2)" "unprognostic (1.06e-1)" "unprognostic (3.27e-2)" 100.4 154.2 60.0 89.3 67.6 81.6 97.1 67.0 62.8 93.6 78.3 137.4 114.8 74.4 122.7 176.4 86.1 86.9 75.7 61.1 64.1 106.3 224.8 79.6 94.6 67.0 65.1 92.9 122.3 100.9 82.9 99.0 66.9 94.3 151.4 73.8 101.1 104.2 105.2 101.7 120.0 104.6 65.6 102.2 118.6 107.1 68.5 94.5 85.9 85.1 143.5 101.0 106.5 76.1 203.1 111.0 131.1 146.8 233.7 275.7 100.9 297.1 261.1 254.3 253.2 157.6 299.3 143.9 242.7 297.7 205.1 213.3 152.2 176.7 322.2 180.8 156.1 163.9 247.2 153.0 252.5 181.3 188.6 225.0 176.1 264.3 233.1 175.4 235.8 160.3 197.8 232.6 299.8 141.5 127.2 127.3 87.5 314.1 279.0 146.0 131.9 183.7 227.5 94.3 109.9 126.2 167.9 376.9 242.9 143.7 149.6 127.4 171.8 197.3 114.1 355.9 219.5 223.0 270.2 255.3 209.6 254.8 102.8 239.1 235.5 284.5 195.9 268.2 180.0 169.0 169.8 210.0 221.2 151.7 127.0 155.9 351.3 164.8 275.9 256.1 244.5 309.0 60.0 67.6 67.0 62.8 61.1 64.1 67.0 65.1 66.9 65.6 68.5 76.1 88.7 64.1 50.0 23.5 73.1 53.2 84.4 214.2 50.1 33.6 111.9 123.6 41.6 118.7 131.4 104.8 33.3 233.8 97.5 218.9 66.5 213.4 475.6 89.5 93.5 68.2 36.5 57.2 16.7 258.4 321.8 94.3 71.9 118.8 44.3 76.5 82.1 233.5 217.9 37.0 16.8 158.6 122.1 104.3 73.2 464.0 82.6 99.9 62.2 15.9 126.1 97.0 114.4 19.1 25.8 256.4 195.4 76.0 145.1 142.5 238.7 119.6 136.3 62.6 111.7 60.9 141.6 291.4 145.2 103.4 67.1 467.9 74.3 159.0 162.0 141.0 RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617038 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 91.4;skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Cytotrophoblasts: 53.7;Exocrine glandular cells: 59.3;Glandular and luminal cells: 197.7;Pancreatic endocrine cells: 51.5;Proximal tubular cells: 152.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.3;T-cells: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.0;GAMG: 20.3;HSkMC: 28.8;MOLT-4: 20.4;RPTEC TERT1: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" 15.6 3.5 20.6 6.6 26.4 2.0 13.6 23.9 33.2 13.2 21.6 24.6 12.6 4.0 5.2 3.6 7.5 13.4 91.4 19.4 22.1 61.0 44.2 9.3 6.4 27.2 25.2 2.1 37.7 30.1 9.9 13.2 27.8 11.1 32.4 7.5 5.2 5.0 141.8 10.0 25.6 2.6 23.6 2.3 10.9 12.3 25.0 20.6 6.7 81.9 4.3 2.3 5.2 37.6 1.3 0.5 0.1 3.5 26.0 3.2 15.1 0.1 3.5 3.1 4.1 2.3 0.1 0.3 2.4 0.0 20.3 3.9 7.8 0.8 1.0 4.1 3.4 0.0 10.6 0.0 0.1 5.3 0.0 28.8 11.7 0.6 3.1 7.5 0.0 15.4 0.0 0.1 1.2 1.0 20.4 0.1 0.8 3.4 0.6 3.2 0.0 1.2 26.2 0.9 17.4 2.0 1.0 1.1 13.1 1.9 5.9 2.4 0.0 2.4 0.2 6.4 3.1 0.7 0.0 0.0 14.9 18.0 6.5 2.3 0.1 0.0 0.2 0.0 0.6 0.0 0.6 0.3 0.0 0.3 1.7 1.0 0.9 0.0 0.0 0.0 0.8 0.2 20.6 26.4 23.9 33.2 19.4 22.1 27.2 25.2 27.8 23.6 25.0 37.6 4.2 73.7 8.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 33.3 19.0 0.0 0.0 9.9 44.1 0.0 53.7 2.2 0.0 17.6 31.1 0.0 33.5 45.2 1.2 0.0 0.0 0.0 59.3 2.0 7.8 0.0 197.7 1.3 3.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.8 0.0 0.0 152.8 19.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 10.9 8.1 0.3 0.0 0.0 RETREG3 "DKFZp686B1036, FAM134C, FLJ33806" ENSG00000141699 "Reticulophagy regulator family member 3" Q86VR2 17 42579513-42610623 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.8;Collecting duct cells: 31.3;Pancreatic endocrine cells: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016492 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear membrane" Cytosol "HPA016492: AB_1853027" "unprognostic (6.79e-2)" "unprognostic (1.29e-2)" "unprognostic (2.78e-1)" "prognostic favorable (1.61e-4)" "unprognostic (5.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.53e-2)" "unprognostic (2.21e-1)" "unprognostic (2.61e-1)" "unprognostic (2.58e-2)" "unprognostic (1.00e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.24e-1)" "unprognostic (5.68e-1)" "unprognostic (9.64e-3)" "unprognostic (5.43e-2)" 16.2 21.7 17.3 13.2 16.6 6.9 16.9 16.4 18.9 23.0 18.7 19.0 14.2 18.5 21.3 29.2 16.8 10.9 16.2 17.0 17.4 19.5 33.4 17.4 19.5 16.9 18.0 19.6 39.9 18.9 20.4 20.9 17.7 25.5 16.8 31.4 23.2 14.0 22.4 33.9 20.7 15.1 16.8 30.1 22.8 38.7 19.1 20.6 16.3 16.4 21.6 19.4 23.1 15.0 12.0 36.6 15.8 25.8 39.6 21.9 22.5 16.9 22.7 19.6 22.9 17.5 25.3 26.3 23.1 27.5 20.1 45.9 20.5 25.3 18.9 28.2 19.3 10.7 22.2 31.0 27.2 18.6 26.5 33.6 34.2 21.5 21.8 21.7 21.3 19.0 22.3 25.4 15.7 20.7 27.5 26.9 10.0 22.5 9.0 14.7 24.2 27.2 22.5 38.2 28.2 19.3 18.1 14.6 26.1 28.9 41.5 14.2 27.2 21.0 12.8 21.1 16.2 43.4 55.3 22.7 19.3 11.6 16.2 54.9 16.2 36.4 44.5 19.2 39.1 23.7 36.5 42.9 15.1 24.8 35.1 40.4 13.8 28.2 24.1 15.0 57.0 36.4 17.3 16.6 16.4 18.9 17.0 17.4 16.9 18.0 17.7 16.8 19.1 15.0 16.7 25.6 29.8 0.0 8.8 0.0 0.0 0.0 0.0 0.0 21.7 18.3 0.0 0.0 6.2 31.3 0.0 22.4 24.7 0.0 7.9 16.4 0.0 14.5 16.7 7.4 0.0 0.0 0.0 25.4 16.0 7.4 0.0 20.0 7.6 26.8 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.8 0.0 0.0 8.8 0.0 0.0 13.4 5.1 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 20.4 8.1 17.3 0.0 0.0 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Microglial cells: 57.1;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 73.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 10.3 8.9 11.2 13.6 20.9 11.9 11.5 12.2 13.6 11.6 1.8 11.5 10.3 13.6 12.5 11.5 12.9 10.9 10.3 8.8 15.2 12.0 15.1 9.9 16.1 15.6 15.0 13.6 13.9 16.5 4.4 9.9 17.1 13.1 11.2 7.4 9.6 13.3 8.9 8.8 11.8 14.3 15.7 14.2 11.4 17.4 16.8 37.5 15.6 8.6 16.9 11.5 7.0 22.8 10.7 9.3 9.9 15.1 28.6 28.8 0.0 24.1 20.9 12.6 14.6 8.3 18.7 10.1 19.8 25.2 18.0 11.9 0.1 26.8 23.9 25.1 9.9 15.3 5.9 6.7 31.5 15.2 8.0 25.6 38.2 23.8 51.4 14.3 9.8 26.7 41.7 25.6 13.4 18.9 27.8 8.5 0.0 12.2 10.3 12.0 0.1 14.9 10.3 13.3 9.7 7.3 13.6 5.1 18.8 17.6 14.1 18.9 13.1 5.6 12.2 22.0 7.5 28.8 14.9 73.9 17.8 19.6 16.2 10.4 13.7 12.8 7.3 20.0 11.8 22.1 11.0 8.9 17.2 24.5 12.6 10.6 3.3 11.8 13.8 21.1 16.2 10.8 11.2 20.9 12.2 13.6 8.8 15.2 15.6 15.0 17.1 15.7 16.8 22.8 6.6 12.8 6.4 66.9 28.4 5.2 8.5 7.2 8.0 8.0 7.6 4.2 16.6 4.3 8.1 11.0 16.7 7.6 9.3 6.6 3.9 7.0 16.7 8.3 8.6 6.8 1.8 15.2 28.4 9.3 4.1 9.3 8.2 7.8 8.2 22.7 3.3 14.0 5.2 11.8 41.5 6.1 6.1 8.2 4.4 24.4 5.6 7.6 12.4 57.1 6.2 6.3 9.2 55.8 109.0 8.3 1.9 6.8 48.8 13.2 6.8 3.4 7.1 6.3 0.0 5.6 6.6 15.2 9.5 7.3 5.5 5.6 8.6 25.7 5.7 8.9 RHBDD3 "C22orf3, PTAG" ENSG00000100263 "Rhomboid domain containing 3" Q9Y3P4 22 29259872-29268209 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043979 Approved Approved Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Microtubules "HPA043979: AB_10960539" "unprognostic (9.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.22e-1)" "prognostic favorable (2.67e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.13e-3)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.42e-3)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.11e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (3.42e-3)" 7.6 20.7 6.8 2.4 7.7 2.9 6.9 6.7 10.8 7.2 6.4 7.3 4.9 9.0 1.3 8.6 8.6 1.7 10.2 6.4 7.2 10.0 16.8 6.7 1.9 8.7 7.9 8.0 11.8 2.6 14.8 2.1 7.7 13.4 0.6 0.9 7.7 4.4 10.1 6.2 7.1 1.6 7.1 10.7 7.1 22.2 7.3 2.3 10.7 0.5 0.9 7.0 6.0 7.6 4.6 7.7 4.2 12.3 1.3 2.2 23.5 2.9 3.8 3.5 4.4 6.9 10.1 12.6 12.4 2.8 2.1 14.2 2.5 2.3 0.4 16.7 19.9 4.6 6.5 8.6 15.0 10.4 11.5 6.6 6.2 1.5 4.2 2.5 4.8 5.1 5.6 8.3 2.6 9.0 6.8 15.8 19.8 2.9 8.6 11.9 7.8 14.6 1.5 4.6 9.2 4.8 9.9 10.6 12.3 1.0 7.0 9.0 7.0 9.5 4.2 4.0 4.4 20.3 6.6 15.1 4.0 4.6 8.1 0.0 4.6 1.9 2.5 4.1 3.1 1.8 2.4 3.7 4.7 0.9 1.8 2.5 1.4 3.6 3.8 11.2 3.9 2.5 6.8 7.7 6.7 10.8 6.4 7.2 8.7 7.9 7.7 7.1 7.3 7.6 8.4 6.4 7.0 22.2 5.1 6.1 11.7 19.9 5.2 17.2 12.1 9.8 8.4 8.6 16.0 14.7 6.2 44.4 12.8 19.0 0.0 18.6 9.0 19.0 12.8 10.0 8.4 11.2 14.4 19.8 18.7 14.1 21.9 24.6 0.0 21.7 12.8 15.7 25.6 16.8 16.5 15.1 12.2 9.7 5.5 7.4 14.0 7.5 7.2 12.2 7.8 14.5 7.2 11.1 9.9 13.2 16.1 12.0 9.5 16.0 15.9 7.1 12.1 22.9 6.6 9.0 10.2 29.8 26.6 8.6 6.0 38.3 7.4 26.3 17.7 9.6 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 58.4;Kupffer cells: 57.3;NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.3 10.1 9.4 31.2 8.6 29.7 13.6 11.7 11.0 8.8 11.6 9.0 6.5 7.4 1.6 23.9 10.1 10.3 10.3 9.7 12.1 10.9 6.3 24.8 27.6 26.6 17.2 8.0 19.5 3.1 5.3 9.7 22.4 9.1 4.4 2.9 11.6 2.6 13.5 29.1 26.6 6.4 20.9 42.2 10.5 3.0 30.0 6.5 12.3 3.1 21.3 11.0 15.7 28.8 38.3 43.3 1.3 10.7 0.4 1.1 30.1 8.6 26.9 6.7 9.1 13.3 45.0 41.5 28.6 10.9 39.0 29.9 7.3 40.8 6.2 7.1 13.6 2.8 3.5 21.8 25.6 1.8 5.9 4.5 20.2 18.1 20.7 15.4 20.3 5.9 4.3 18.3 4.6 30.7 4.3 4.7 6.7 25.7 26.1 10.3 0.4 75.3 17.8 14.0 9.2 12.6 9.9 28.7 38.7 8.5 24.7 11.4 32.4 0.6 14.4 0.7 11.0 44.3 22.6 33.7 24.3 11.2 27.1 6.3 13.4 4.3 8.0 13.1 5.5 12.7 2.1 5.8 6.5 7.4 1.5 3.6 10.2 4.9 12.2 10.0 1.1 8.8 9.4 8.6 11.7 11.0 9.7 12.1 26.6 17.2 22.4 20.9 30.0 28.8 22.3 6.4 6.9 2.3 58.4 17.6 15.3 35.0 8.0 4.2 4.7 5.5 3.3 18.6 19.2 3.7 2.1 1.0 47.1 2.0 0.0 21.3 0.5 4.2 0.8 15.3 1.8 1.3 0.6 9.8 2.2 4.7 7.7 6.6 0.0 15.4 7.9 3.4 37.6 0.0 0.5 4.1 6.1 57.3 42.7 0.7 0.9 48.8 10.6 38.4 40.1 1.1 64.9 1.0 0.1 14.2 4.8 0.4 36.5 20.4 1.9 1.8 16.2 1.4 6.6 3.6 3.2 0.7 7.1 9.9 29.3 1.6 22.3 2.8 7.8 20.4 RNASEK MGC71993 ENSG00000219200 "Ribonuclease K" Q6P5S7 17 7012417-7014532 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 246.4;Macrophages: 174.7;Plasma cells: 253.2;Squamous epithelial cells: 250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044708 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "HPA044708: AB_10962051" "unprognostic (7.59e-2)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "unprognostic (5.92e-2)" "unprognostic (9.73e-3)" "unprognostic (4.82e-2)" "unprognostic (3.65e-1)" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (6.50e-3)" "prognostic favorable (1.92e-4)" "unprognostic (2.93e-3)" "unprognostic (1.72e-3)" "unprognostic (1.81e-1)" "unprognostic (1.77e-2)" "unprognostic (1.14e-1)" "unprognostic (2.33e-3)" 309.4 592.6 276.9 173.8 296.6 292.9 278.5 285.0 391.0 252.6 339.9 271.8 161.1 254.5 135.1 241.5 239.4 173.3 325.9 298.9 381.3 515.3 280.2 347.4 217.8 307.5 307.5 265.2 233.9 287.8 505.1 158.7 323.9 255.0 118.2 81.6 246.4 161.1 321.9 297.0 229.1 144.9 275.9 396.8 275.2 180.2 300.6 159.6 256.0 226.6 166.8 231.1 225.3 288.4 223.4 353.3 160.9 276.4 406.6 363.4 142.8 224.5 389.5 283.9 320.6 149.6 205.6 157.2 221.3 435.5 343.2 328.5 199.1 274.7 153.6 319.2 520.8 157.0 264.7 252.9 466.1 99.9 748.3 462.4 321.7 338.5 194.0 316.1 344.6 168.0 138.1 327.7 348.4 206.0 137.0 327.4 111.7 178.2 314.0 160.7 92.3 180.9 374.2 192.4 82.1 291.9 191.0 135.6 421.5 157.8 176.0 177.3 322.5 304.6 132.8 383.9 289.3 267.6 278.0 68.6 475.7 225.3 253.2 993.4 1136.6 1378.0 373.6 1031.0 369.9 593.4 413.9 381.0 848.3 542.0 329.5 321.0 2175.1 420.9 1007.1 1070.5 451.1 1052.7 276.9 296.6 285.0 391.0 298.9 381.3 307.5 307.5 323.9 275.9 300.6 288.4 21.3 57.7 65.7 0.0 109.7 20.5 9.2 16.3 246.4 16.3 21.6 14.9 0.8 8.6 47.9 5.5 41.7 5.3 31.5 21.0 3.9 21.4 5.8 45.4 32.4 37.9 13.2 62.0 0.0 5.5 3.4 58.9 110.1 38.6 54.2 14.4 20.0 16.2 14.2 11.8 0.0 15.9 8.2 62.3 47.0 6.2 9.0 174.7 21.4 0.0 42.4 7.6 28.8 0.0 0.0 12.1 10.8 6.4 253.2 12.1 20.4 6.7 58.8 31.5 26.3 11.4 35.6 3.6 1.2 250.2 21.7 11.8 98.0 15.9 15.1 13.8 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 295.7;Kupffer cells: 393.7;Macrophages: 283.0;monocytes: 276.4;Oligodendrocytes: 514.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 261.6;classical monocyte: 513.2;eosinophil: 331.3;intermediate monocyte: 355.0;myeloid DC: 407.4;neutrophil: 890.5;non-classical monocyte: 328.7;plasmacytoid DC: 317.2" "Group enriched" "Detected in all" 11 "dendritic cells: 407.4;granulocytes: 890.5;monocytes: 513.2" "Cell line enhanced" "Detected in many" "HMC-1: 179.3" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 94.2 43.4 79.7 47.7 103.2 94.0 50.2 102.3 114.1 55.5 75.5 40.1 28.1 42.1 35.6 26.4 46.8 55.9 36.2 81.4 85.8 49.4 167.1 62.6 39.2 112.8 94.6 52.2 64.2 28.0 16.6 48.4 110.6 35.1 41.9 14.3 84.6 60.2 33.2 14.6 32.6 52.6 98.4 51.8 34.7 17.5 92.3 17.7 32.3 53.7 25.8 51.6 19.3 138.2 32.7 26.8 125.5 110.9 117.4 54.5 21.9 20.9 29.1 24.1 25.3 8.4 31.8 0.1 69.6 47.5 47.7 3.0 81.5 49.7 26.0 0.3 54.6 57.7 11.8 25.4 27.3 14.9 179.3 52.2 25.9 2.3 15.3 65.6 42.3 57.3 9.7 0.4 27.0 71.0 28.7 68.8 32.7 6.7 33.8 65.9 27.9 0.1 38.7 7.4 68.4 28.8 43.2 34.4 126.5 45.7 40.8 38.6 36.6 50.6 18.9 38.8 27.1 0.4 24.1 6.2 7.7 132.0 41.2 261.6 513.2 331.3 25.4 355.0 21.7 15.8 10.9 12.3 407.4 15.8 12.4 13.6 890.5 53.6 328.7 317.2 1.6 323.8 79.7 103.2 102.3 114.1 81.4 85.8 112.8 94.6 110.6 98.4 92.3 138.2 75.0 19.2 21.4 119.1 22.4 14.1 22.6 27.0 12.5 26.9 55.0 45.5 35.1 81.5 34.7 42.3 52.1 11.2 123.7 26.9 23.5 56.8 11.8 49.0 38.8 48.3 16.3 69.2 119.0 76.5 16.6 57.9 25.5 38.3 82.9 28.9 47.5 147.0 295.7 6.7 144.0 36.1 36.7 393.7 170.7 24.2 36.7 283.0 32.0 141.5 276.4 21.8 28.8 242.8 514.2 41.6 32.1 48.2 11.7 27.2 32.6 52.0 56.3 20.3 46.0 32.4 48.5 13.2 32.9 10.9 12.9 8.8 26.2 33.7 52.9 23.3 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474880-124488618 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 93.2" "Group enriched" "Detected in all" 10 "Early spermatids: 810.1;Late spermatids: 992.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 23.5 20.8 10.0 15.9 11.1 93.2 18.9 14.8 12.7 16.6 11.2 15.6 9.2 20.2 13.6 16.5 16.7 16.8 15.3 11.0 11.0 15.3 26.1 16.6 17.3 11.0 10.8 23.6 14.4 11.8 10.2 19.4 11.0 14.9 14.8 12.4 16.5 13.3 20.3 17.2 14.2 20.3 11.8 13.9 13.9 68.7 11.7 19.3 16.3 22.6 14.8 16.7 12.4 15.0 26.6 17.1 21.6 20.3 43.2 34.1 16.6 23.5 44.4 18.6 24.7 10.9 21.6 27.5 27.8 31.7 14.3 19.7 18.3 28.4 28.9 37.6 24.5 41.1 11.9 22.9 33.3 19.6 23.2 30.5 41.0 20.5 55.9 27.1 26.2 26.8 29.1 41.3 22.2 70.2 32.9 13.6 14.3 52.6 25.6 13.2 14.9 27.0 35.3 34.4 9.4 22.3 31.0 76.5 33.4 16.5 35.7 20.7 20.6 13.9 29.7 22.2 26.3 32.9 40.9 28.6 19.9 31.7 13.9 2.7 6.2 10.1 8.7 4.1 11.0 7.9 7.8 10.5 8.4 7.1 8.1 8.4 8.5 7.2 11.4 4.0 11.4 6.7 10.0 11.1 14.8 12.7 11.0 11.0 11.0 10.8 11.0 11.8 11.7 15.0 21.1 3.2 8.4 11.8 66.2 66.2 62.1 27.2 58.6 14.5 31.6 19.7 16.2 34.3 18.5 22.0 6.2 42.3 58.5 22.5 11.7 19.9 810.1 31.3 22.6 24.9 21.7 27.1 12.9 18.0 55.9 40.1 23.4 37.1 20.3 23.2 22.9 31.8 25.0 16.8 12.8 18.5 10.2 33.7 74.4 992.2 29.5 43.4 35.6 12.2 26.5 21.3 26.8 8.5 18.5 22.5 11.4 27.1 35.4 41.1 17.0 16.9 20.1 22.7 19.7 39.7 49.2 62.3 24.3 46.7 70.5 75.5 83.5 22.6 18.2 55.5 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "HPA050931: AB_2681279, HPA054621: AB_2682545" "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 9.3 11.7 14.5 7.5 15.6 2.4 12.7 16.3 16.8 7.9 11.5 11.1 10.3 9.5 14.9 14.2 9.3 9.2 7.7 14.1 15.8 16.4 19.7 9.3 9.4 15.9 15.5 12.3 8.1 13.5 9.5 19.2 16.2 11.0 11.3 35.6 11.0 10.6 11.9 15.1 11.4 7.6 15.0 9.1 10.7 5.9 15.6 6.1 28.8 9.2 9.9 7.6 8.5 18.3 11.4 18.1 18.2 9.2 29.4 29.7 10.8 13.3 18.1 12.3 13.2 8.5 36.0 13.6 15.7 12.8 22.1 9.6 9.6 13.2 10.8 9.4 10.4 15.9 8.5 9.3 16.1 2.0 10.9 26.0 20.4 9.3 18.8 16.0 13.3 15.0 14.6 15.8 19.9 3.4 17.0 9.5 8.6 24.1 6.5 8.7 24.2 7.7 19.6 10.8 4.7 14.3 12.8 8.9 23.0 17.7 23.1 9.5 19.5 13.2 5.8 17.8 4.3 25.2 26.4 15.7 18.2 6.7 13.6 1.4 5.7 2.1 2.9 5.7 4.2 6.6 4.8 5.3 8.8 3.9 5.6 4.1 0.6 4.9 5.5 8.9 6.7 4.5 14.5 15.6 16.3 16.8 14.1 15.8 15.9 15.5 16.2 15.0 15.6 18.3 13.5 48.1 20.5 41.1 16.1 7.6 13.1 22.3 5.7 44.8 14.9 9.5 11.5 15.7 29.2 23.9 89.6 41.6 9.8 22.1 17.6 21.6 1.7 16.0 14.5 15.2 13.1 5.5 36.7 27.8 19.4 20.0 11.2 13.3 9.5 25.5 21.8 21.7 22.9 21.9 43.7 15.3 20.3 18.5 9.2 2.4 15.2 15.4 8.8 15.9 21.9 31.8 30.9 36.2 75.9 32.2 18.4 20.7 10.7 9.6 34.5 22.1 33.3 72.1 13.1 23.9 12.1 14.9 19.3 12.5 11.5 31.2 12.8 25.7 16.6 12.2 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7;choroid plexus: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 85.2" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 81.3;RPTEC TERT1: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.1 0.1 12.2 0.1 13.3 8.4 0.6 22.5 17.7 0.8 12.7 0.2 0.2 0.6 1.1 0.3 1.2 0.2 0.3 17.6 12.2 1.1 0.0 3.3 0.2 16.9 17.7 0.3 1.7 5.8 1.8 1.3 16.5 0.4 0.1 8.8 1.3 2.1 0.2 0.4 0.3 0.3 14.2 0.2 0.2 3.7 24.7 1.5 1.3 0.1 0.0 0.3 0.4 12.2 0.2 6.5 12.0 0.0 4.1 5.0 0.7 6.3 8.6 17.0 16.4 0.3 0.1 0.0 0.1 6.8 18.5 0.0 14.3 0.1 30.9 0.0 4.7 0.4 81.3 0.0 0.0 0.1 0.0 2.8 0.0 26.3 0.2 19.5 0.3 3.5 0.5 0.0 11.9 0.2 0.1 2.2 6.9 0.1 23.9 3.8 2.9 1.0 67.3 0.0 14.2 13.7 0.6 0.0 24.8 4.4 0.0 2.4 6.5 20.7 4.4 0.2 14.3 0.0 0.0 0.0 14.1 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 13.3 22.5 17.7 17.6 12.2 16.9 17.7 16.5 14.2 24.7 12.2 0.2 0.0 0.0 85.2 0.1 0.3 0.1 0.0 0.0 19.3 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.4 0.1 0.2 0.0 9.7 8.6 0.0 0.1 0.4 0.0 0.1 0.0 5.4 0.0 0.1 0.1 15.2 1.5 0.1 0.0 0.0 0.3 1.4 0.3 0.0 0.0 5.6 0.0 14.7 0.0 2.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 1.1 0.1 1.3 6.6 0.0 1.3 5.7 3.2 0.0 0.0 0.3 0.3 0.0 0.1 0.1 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 RNF186 FLJ20225 ENSG00000178828 "Ring finger protein 186" Q9NXI6 1 19814029-19815283 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 67.2;intestine: 131.1;pancreas: 43.4" "Group enriched" "Detected in some" 5 "Distal enterocytes: 41.6;Enteroendocrine cells: 86.6;Intestinal goblet cells: 46.6;Paneth cells: 123.4;Proximal tubular cells: 142.7;Undifferentiated cells: 110.3" "Group enriched" "Detected in many" 4 "colorectal cancer: 18.5;renal cancer: 12.1;stomach cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034547, HPA035558" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA034547: AB_10670975, HPA035558: AB_2674678" "unprognostic (1.66e-2)" "unprognostic (2.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.93e-3)" "unprognostic (1.77e-3)" "unprognostic (3.23e-1)" "unprognostic (3.05e-1)" "unprognostic (3.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.76e-1)" "unprognostic (1.40e-1)" "unprognostic (8.60e-3)" 0.3 0.0 0.0 5.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 18.7 131.1 0.1 67.2 0.0 0.0 0.4 0.0 0.0 0.0 26.1 0.8 0.0 0.0 0.0 0.0 0.2 43.4 0.0 0.0 0.0 0.0 0.3 15.4 0.0 0.3 0.4 0.0 0.0 44.8 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 41.6 5.9 9.6 0.0 0.8 0.1 0.1 86.6 0.0 0.0 18.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 123.4 0.0 0.0 0.1 16.1 142.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 110.3 0.2 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 178.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favorable (3.28e-5)" 32.0 18.8 29.1 32.7 28.7 57.4 28.6 22.7 25.5 52.0 17.6 25.9 24.0 41.3 16.4 21.6 30.5 43.1 25.0 25.3 48.3 30.0 49.3 34.7 55.4 40.2 36.0 27.4 25.9 16.1 15.2 26.9 33.0 22.0 26.5 27.2 22.3 18.7 28.0 31.8 37.9 32.6 37.3 31.5 27.4 53.0 36.1 34.3 18.8 31.0 43.8 35.9 27.3 40.7 26.7 16.9 14.8 16.9 27.7 23.1 18.7 23.4 22.5 22.0 19.9 9.0 17.3 15.7 41.6 24.7 10.2 18.9 11.6 17.4 29.6 65.3 9.4 26.1 86.8 13.5 22.8 5.3 15.6 23.3 26.1 17.5 33.1 26.9 34.3 17.3 14.8 178.6 21.8 13.5 24.6 9.0 5.4 18.2 15.5 9.8 10.0 30.7 60.2 41.7 11.4 24.6 24.5 14.9 23.3 30.6 13.1 20.5 33.9 25.3 19.9 18.7 14.3 85.5 59.3 10.4 16.2 17.4 15.4 26.3 8.6 8.1 16.3 6.8 10.4 15.5 13.4 12.6 5.7 13.9 6.9 9.8 19.6 6.2 14.2 14.1 14.7 5.8 29.1 28.7 22.7 25.5 25.3 48.3 40.2 36.0 33.0 37.3 36.1 40.7 70.8 51.3 51.6 106.7 101.7 40.1 83.4 56.9 18.8 29.9 44.7 32.5 40.6 110.1 83.6 44.1 60.5 11.0 184.8 61.6 7.9 65.0 183.8 165.9 78.2 66.3 20.8 124.8 76.9 40.2 14.5 62.5 67.8 242.1 43.0 172.0 32.2 42.9 23.0 58.9 69.7 25.9 42.7 30.5 41.8 259.4 58.4 39.2 21.4 73.1 24.1 43.5 65.9 35.7 39.9 49.0 32.0 68.8 161.7 66.3 50.9 54.1 106.2 48.4 19.7 77.4 46.3 77.8 47.2 26.1 60.4 8.2 204.6 46.3 21.8 144.9 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Cell line enhanced" "Detected in all" "Daudi: 107.6;Karpas-707: 124.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 14.5 19.1 10.7 24.3 9.6 74.1 10.9 14.5 10.7 16.8 7.6 23.3 25.0 15.0 5.0 35.3 12.3 17.4 10.4 9.9 12.1 21.1 11.3 21.1 17.7 10.7 9.6 9.7 9.2 11.5 7.9 14.9 11.8 11.0 25.8 18.9 15.4 8.9 16.2 22.6 21.7 18.0 11.6 15.1 13.1 79.0 10.8 13.0 9.0 11.1 30.6 30.1 20.9 11.6 18.7 14.3 11.9 11.3 7.1 9.6 79.5 8.5 10.0 14.7 15.6 16.8 54.9 107.6 14.2 10.7 18.2 26.5 14.3 19.8 13.3 39.6 9.5 9.2 10.5 16.9 22.5 14.7 19.0 7.9 36.3 32.5 39.3 17.2 31.9 10.3 11.7 124.8 14.5 6.1 9.6 18.4 19.2 21.1 15.8 12.7 17.3 11.3 11.5 26.4 18.9 9.6 27.0 9.1 63.1 29.1 8.0 20.8 35.1 8.1 11.5 21.1 15.1 29.6 16.1 38.0 11.9 14.7 12.5 6.1 2.0 4.0 1.6 1.9 1.3 1.2 1.4 0.7 1.4 1.5 0.4 0.6 16.9 1.0 1.7 0.6 1.7 0.8 10.7 9.6 14.5 10.7 9.9 12.1 10.7 9.6 11.8 11.6 10.8 11.6 20.6 12.8 4.4 5.5 8.7 46.1 27.0 26.7 24.5 4.6 15.8 11.7 16.2 10.0 9.9 7.3 2.1 12.6 14.6 48.0 1.9 12.9 34.8 25.4 7.3 15.3 11.3 5.2 9.7 11.5 6.3 8.4 13.3 36.9 4.5 3.2 7.1 4.8 13.5 3.3 9.8 22.1 6.1 20.9 37.7 26.3 2.1 42.4 5.4 19.7 39.5 2.8 2.1 7.5 6.6 25.7 31.9 3.8 4.6 34.2 38.6 9.2 14.4 7.7 0.0 5.9 9.6 34.7 16.3 23.9 32.5 7.4 10.3 2.3 16.3 41.7 RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 396.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 7.4 9.9 6.8 18.6 12.9 25.6 7.0 9.0 11.3 8.0 13.0 9.0 8.7 7.8 8.7 7.1 8.6 10.7 6.5 5.1 6.9 10.5 6.2 13.2 17.9 23.5 11.4 9.0 7.8 34.2 6.6 10.0 18.3 7.1 7.8 12.0 10.8 6.8 6.6 8.8 10.6 9.1 13.8 18.7 11.1 3.4 16.5 20.2 11.0 7.6 14.5 11.0 7.1 17.3 40.1 69.7 6.9 4.9 24.4 37.0 5.1 9.9 21.4 43.7 37.1 7.5 18.1 2.6 8.3 20.8 46.6 22.7 9.3 12.9 14.7 90.8 4.3 6.3 29.9 13.3 10.5 6.7 6.2 20.5 8.6 24.6 10.6 13.7 34.3 28.3 11.8 14.5 16.5 9.7 26.7 2.8 5.1 7.5 16.0 18.0 15.9 3.1 12.1 34.1 6.6 9.2 24.1 50.3 17.3 15.3 11.6 8.2 44.5 24.2 19.0 14.4 10.3 6.3 6.3 7.0 18.2 7.6 8.9 19.5 20.8 10.4 26.2 18.5 17.5 15.3 18.6 21.6 5.4 15.5 14.6 18.2 84.5 26.1 17.1 32.0 15.4 4.8 6.8 12.9 9.0 11.3 5.1 6.9 23.5 11.4 18.3 13.8 16.5 17.3 76.1 89.8 56.9 56.8 89.9 35.8 37.2 39.2 43.3 21.2 59.9 41.7 32.6 75.8 50.3 101.2 50.1 21.0 240.8 117.4 13.7 120.3 1.4 58.7 58.9 90.7 46.0 30.3 23.6 162.4 31.5 50.8 158.0 93.4 46.7 140.7 74.3 56.4 98.0 23.5 15.5 68.2 32.6 136.5 94.9 3.7 60.9 128.9 30.2 87.1 194.6 26.1 396.5 32.2 70.4 166.1 76.2 51.6 167.6 100.8 116.3 92.2 66.2 68.5 65.7 52.3 53.7 1.4 8.2 43.0 34.4 21.8 211.6 84.7 54.9 66.5 RNF215 ENSG00000099999 "Ring finger protein 215" Q9Y6U7 22 30368811-30421771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.9;Cone photoreceptor cells: 12.5;Rod photoreceptor cells: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029427, HPA056498" Approved Approved Nucleoli,Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" Microtubules Nucleoli "HPA029427: AB_2732447, HPA056498: AB_2683154" "unprognostic (1.24e-2)" "unprognostic (3.20e-1)" "unprognostic (3.67e-4)" "unprognostic (8.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (1.97e-1)" "unprognostic (5.32e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (6.37e-10)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" 8.4 8.7 19.2 5.6 19.0 7.0 9.3 18.7 22.5 17.6 17.9 11.8 7.8 15.2 9.2 6.7 13.3 6.8 9.5 19.2 20.4 12.1 11.1 8.7 4.7 20.2 18.7 13.7 13.2 10.7 10.0 6.9 18.3 13.1 3.9 8.5 6.5 8.3 8.0 6.1 7.7 7.9 16.9 11.6 8.9 10.5 20.0 2.8 12.2 2.9 3.9 12.3 10.8 17.4 6.8 14.0 14.4 23.4 13.8 14.3 14.2 11.4 10.1 11.3 6.8 3.8 7.4 2.7 20.1 9.3 21.1 8.4 8.9 13.1 9.0 15.8 10.8 4.5 17.8 5.1 18.9 3.6 18.5 19.4 15.8 19.3 10.3 36.7 13.3 7.0 4.0 12.6 13.6 11.0 2.6 8.5 4.5 9.7 15.4 12.2 8.4 10.8 14.9 10.3 6.3 16.2 11.6 8.3 8.9 13.1 7.6 3.9 18.6 30.2 13.3 8.8 6.7 13.3 3.4 3.7 17.7 2.6 11.9 0.4 0.9 1.5 0.9 0.7 1.0 1.0 1.0 0.8 0.5 1.9 1.8 1.7 0.5 2.5 0.8 1.4 0.5 0.4 19.2 19.0 18.7 22.5 19.2 20.4 20.2 18.7 18.3 16.9 20.0 17.4 7.1 3.2 3.9 8.8 1.4 0.3 1.2 1.6 2.8 12.9 3.2 3.9 2.2 1.5 2.7 0.0 12.5 1.9 3.7 1.0 0.0 1.5 0.8 3.7 6.4 3.5 0.0 0.4 5.0 1.4 1.5 5.4 6.1 6.6 0.0 8.2 4.6 2.3 1.8 8.4 4.6 0.5 2.0 1.2 0.5 0.4 0.9 1.9 1.8 1.0 2.3 11.7 1.0 2.5 1.1 1.9 0.2 1.2 1.8 1.3 0.7 1.0 0.6 13.7 6.6 4.8 4.8 2.1 0.9 0.6 0.1 1.6 2.0 5.3 0.7 1.2 RNF217 "C6orf172, dJ84N20.1, IBRDC1, MGC26996" ENSG00000146373 "Ring finger protein 217" Q8TC41 6 124962545-125092633 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 42.7" "Cell type enhanced" "Detected in many" "Early spermatids: 127.8;Oligodendrocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029598 Uncertain NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA029598: AB_10602297" "unprognostic (2.96e-2)" "unprognostic (2.34e-3)" "unprognostic (8.07e-2)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (7.22e-3)" "unprognostic (4.94e-2)" "unprognostic (6.69e-2)" "unprognostic (2.47e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (4.60e-5)" "unprognostic (8.29e-4)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" "prognostic unfavorable (1.92e-4)" 8.0 3.0 3.4 2.0 2.5 11.0 6.0 3.0 2.3 6.3 4.9 7.2 1.3 4.4 2.0 5.0 7.4 4.2 5.1 3.0 2.7 1.9 5.7 6.3 0.7 3.0 1.8 8.6 2.8 42.7 2.9 3.9 2.4 3.5 1.3 3.6 4.7 3.6 7.6 9.1 2.5 4.1 1.1 1.8 3.5 6.9 2.6 1.5 5.8 5.9 0.4 5.3 5.7 5.4 4.9 5.0 1.7 0.6 6.1 2.4 9.7 6.6 8.9 4.4 5.8 0.0 4.6 0.0 9.0 6.3 10.1 7.0 1.0 5.9 6.2 0.0 5.5 2.7 7.6 1.5 5.7 0.0 0.2 6.5 5.4 3.3 9.7 5.2 5.0 0.0 14.0 0.0 7.8 0.0 0.0 0.0 1.5 0.0 1.3 0.1 6.8 0.0 4.5 2.2 0.8 0.0 2.9 0.7 2.5 4.8 4.8 0.8 8.1 3.6 11.5 0.0 14.3 0.0 0.0 0.0 2.7 0.0 4.4 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.5 3.0 2.3 3.0 2.7 3.0 1.8 2.4 1.1 2.6 5.4 25.0 22.4 21.0 49.0 0.6 48.2 15.8 17.5 18.2 6.3 10.0 10.7 14.4 4.3 12.1 5.5 16.7 24.2 0.9 1.3 0.0 8.1 127.8 11.4 21.5 19.0 3.0 6.5 56.3 9.6 29.7 23.1 4.6 22.8 1.3 9.0 15.7 26.9 9.8 21.9 65.0 2.4 12.2 14.6 20.9 62.1 25.7 11.3 19.6 51.5 9.8 4.2 1.0 37.7 102.1 11.8 2.0 21.1 0.4 21.6 6.9 2.3 9.6 5.7 6.6 44.9 12.3 1.7 2.9 17.5 47.0 17.9 1.8 5.3 4.3 16.3 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 599.6;Syncytiotrophoblasts: 621.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB019277: , HPA008297: AB_1856457, HPA025922: AB_1856458" "unprognostic (9.59e-3)" "unprognostic (5.22e-2)" "unprognostic (1.66e-2)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.44e-10)" "unprognostic (2.83e-1)" "unprognostic (6.99e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.44e-4)" 112.6 132.5 48.2 131.9 50.4 180.8 146.1 49.9 55.9 161.8 98.0 156.9 125.5 108.7 344.1 106.8 122.9 119.8 107.3 49.5 56.5 145.1 212.1 129.7 109.2 54.0 50.6 94.8 159.6 180.9 79.1 257.9 53.9 164.4 175.2 117.0 158.2 157.5 110.4 91.5 110.9 156.6 53.8 118.1 145.1 144.2 55.4 108.5 232.5 75.1 143.3 165.4 87.9 61.9 328.2 290.6 302.7 401.2 413.1 308.2 586.7 426.7 516.8 544.8 459.2 939.2 564.8 255.3 501.6 572.3 506.4 468.4 318.8 516.4 492.0 121.2 196.5 295.3 308.4 634.1 398.9 468.4 467.0 294.6 505.1 432.3 447.5 519.8 530.4 239.2 458.7 805.1 389.1 300.9 270.6 451.0 240.4 839.3 415.7 242.3 549.1 852.7 371.6 304.3 246.4 261.0 517.9 1231.1 489.4 353.6 606.1 765.6 338.0 600.8 358.2 317.1 371.9 474.7 608.4 259.9 583.4 314.9 493.2 424.2 427.5 285.5 365.5 410.5 417.0 291.0 336.1 363.8 481.2 232.4 298.8 308.7 78.3 398.8 357.6 591.0 338.2 676.5 48.2 50.4 49.9 55.9 49.5 56.5 54.0 50.6 53.9 53.8 55.4 61.9 85.7 118.6 158.0 22.2 107.8 61.8 134.1 264.6 62.0 72.6 90.0 74.2 81.4 133.0 197.7 80.9 45.9 461.6 109.6 113.9 23.5 278.0 37.3 73.2 103.5 98.6 63.0 91.7 18.8 241.1 599.6 127.4 84.1 151.2 105.2 109.3 100.6 206.3 233.2 63.9 18.6 168.5 162.8 150.4 75.3 24.4 105.0 117.0 90.7 20.6 122.2 136.8 65.9 24.1 20.5 160.1 109.5 110.9 392.3 121.3 64.6 82.3 98.5 100.8 85.5 65.3 122.0 335.2 288.9 67.7 57.8 621.0 81.5 213.7 138.7 117.6 RTN1 NSP ENSG00000139970 "Reticulon 1" Q16799 14 59595976-59870776 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 160.6;pituitary gland: 60.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 495.8;Horizontal cells: 240.6;Inhibitory neurons: 394.3;Oligodendrocyte precursor cells: 188.0;Oligodendrocytes: 247.7" "Cancer enhanced" "Detected in many" "glioma: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.9;intermediate monocyte: 3.1;myeloid DC: 5.4" "Group enriched" "Detected in many" 14 "dendritic cells: 5.4;monocytes: 3.1" "Group enriched" "Detected in some" 4 "HEL: 61.7;SCLC-21H: 71.8;SH-SY5Y: 115.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002745, HPA040945, HPA044249" Enhanced Supported "Nuclear bodies,Endoplasmic reticulum" NA NA 150000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "Nuclear bodies" "CAB002745: , HPA040945: AB_2677217, HPA044249: AB_2678874" "unprognostic (9.40e-3)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (4.24e-2)" "unprognostic (3.04e-3)" "unprognostic (8.67e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (2.79e-1)" "prognostic favorable (3.69e-4)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-2)" "unprognostic (1.75e-1)" "unprognostic (6.71e-2)" "unprognostic (1.62e-2)" 11.1 12.0 111.1 9.3 127.5 0.4 7.2 57.0 134.7 2.2 0.0 7.6 2.5 1.3 0.4 1.6 12.8 5.5 0.9 133.0 160.6 1.6 1.0 6.4 2.7 37.5 24.9 0.7 4.0 17.4 60.1 2.4 46.7 6.4 2.8 34.1 3.4 1.9 0.8 3.2 4.1 2.4 10.8 18.3 3.9 2.3 68.3 1.0 2.5 0.7 1.8 1.9 3.6 50.2 0.0 0.0 0.7 1.0 2.9 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.9 0.1 0.4 0.0 2.1 61.7 0.0 0.0 3.4 0.1 0.2 0.0 0.1 0.0 2.1 0.0 0.5 0.4 0.0 0.3 0.7 0.3 0.0 0.0 4.9 0.0 0.0 0.0 0.6 0.1 0.0 0.0 71.8 115.1 14.9 0.0 0.0 0.2 0.0 0.0 0.0 9.9 2.8 0.1 5.6 0.0 0.0 0.0 19.4 4.4 0.7 0.0 2.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.7 111.1 127.5 57.0 134.7 133.0 160.6 37.5 24.9 46.7 10.8 68.3 50.2 1.0 0.0 1.1 64.3 0.5 4.8 0.4 0.0 0.0 34.1 11.4 4.3 1.0 1.5 0.6 0.0 25.0 1.2 1.4 0.8 0.0 0.0 16.2 23.5 0.3 2.9 54.2 0.8 495.8 0.0 5.0 1.5 5.6 0.4 0.0 0.2 0.0 0.5 17.8 240.6 394.3 3.6 0.0 14.4 59.7 21.4 2.8 23.8 10.6 87.1 22.8 14.3 0.0 188.0 247.7 1.4 0.1 1.2 0.1 5.8 0.8 0.9 0.7 33.3 0.0 10.7 2.5 2.3 3.8 0.2 6.5 2.5 0.7 0.1 0.5 0.3 RTN2 "NSP2, NSPL1, SPG12" ENSG00000125744 "Reticulon 2" O75298 19 45485294-45497055 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 509.8;tongue: 207.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.3;Extravillous trophoblasts: 145.7;Skeletal myocytes: 73.2;Syncytiotrophoblasts: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.2;eosinophil: 2.6;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "dendritic cells: 1.6;granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RH-30: 44.3;RT4: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034941, HPA034948" Approved Approved "Nuclear speckles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "HPA034941: AB_10671358, HPA034948: AB_2674375" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (5.07e-3)" "unprognostic (1.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.89e-2)" "unprognostic (3.09e-1)" "unprognostic (6.44e-2)" "unprognostic (5.10e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.58e-6)" "unprognostic (4.34e-1)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" 9.9 13.6 21.4 3.4 25.7 1.7 12.0 15.9 43.6 5.9 7.8 21.8 2.8 15.2 2.5 12.1 4.6 7.9 21.9 24.7 22.0 7.1 3.9 8.2 4.7 27.3 19.3 1.9 4.8 10.1 7.6 19.2 27.0 17.0 2.2 5.7 22.3 10.6 509.8 9.1 8.7 7.3 14.1 11.2 7.9 1.6 25.1 1.1 4.9 207.7 2.0 12.4 7.8 29.0 3.8 5.2 8.6 6.7 14.4 17.6 16.9 8.5 20.0 5.2 9.9 10.4 3.2 3.3 11.4 9.3 4.2 7.2 5.6 4.1 1.7 7.9 8.2 23.0 3.9 7.8 6.2 1.4 25.0 19.5 2.2 2.3 4.2 9.2 9.6 0.9 12.9 6.2 15.6 2.9 0.0 4.3 6.3 17.0 6.8 3.6 44.3 18.8 3.0 45.0 24.1 23.1 1.7 40.7 13.2 8.0 32.3 9.1 8.6 14.7 4.4 0.4 1.9 3.5 8.7 7.7 3.9 5.2 7.7 6.2 0.1 2.6 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.3 1.6 0.0 0.2 21.4 25.7 15.9 43.6 24.7 22.0 27.3 19.3 27.0 14.1 25.1 29.0 9.8 3.2 8.1 2.6 0.8 6.4 27.7 8.9 6.8 10.4 18.4 21.1 4.6 4.3 4.6 3.7 6.2 134.3 2.9 0.9 0.0 21.3 0.3 2.1 7.0 15.3 11.4 1.7 21.0 6.8 145.7 14.0 3.1 3.4 16.5 4.2 18.9 3.1 27.3 23.5 13.3 2.2 12.2 12.9 12.0 0.4 5.6 10.7 23.2 1.9 6.5 9.1 1.0 4.5 2.1 13.1 0.3 6.8 2.5 13.0 0.3 0.3 1.3 13.6 13.1 73.2 12.3 0.5 3.9 2.3 3.4 120.1 1.0 16.4 0.7 23.2 RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" 207.5 81.8 361.4 54.1 412.2 108.5 93.3 338.4 514.5 87.6 190.7 88.1 54.0 62.5 81.2 55.7 88.5 56.3 57.4 428.4 378.9 92.8 87.5 77.8 36.0 404.5 309.1 48.1 91.1 109.9 81.0 62.2 417.2 53.3 79.9 194.4 138.8 76.1 70.2 103.7 65.2 80.1 329.2 51.7 57.0 46.6 334.0 53.7 175.5 43.7 48.5 55.7 54.2 384.0 157.5 113.8 134.0 128.4 242.3 170.9 53.4 139.3 147.5 120.5 128.4 99.6 338.1 184.2 231.7 210.0 115.7 157.2 194.0 68.7 157.5 149.5 103.5 236.5 151.3 70.4 201.1 212.8 182.4 113.5 199.2 146.7 162.3 200.7 165.2 158.9 136.2 290.1 107.4 129.2 113.4 235.2 156.7 127.3 127.3 148.4 93.8 342.9 239.7 87.5 282.7 164.0 226.2 245.3 271.5 95.4 271.1 172.7 155.2 71.3 95.6 251.1 108.4 183.4 169.9 145.6 274.7 173.8 77.2 441.0 400.1 487.7 41.4 187.6 44.8 28.6 41.6 41.3 130.8 19.4 30.1 32.7 1074.7 41.7 240.4 79.0 68.6 323.0 361.4 412.2 338.4 514.5 428.4 378.9 404.5 309.1 417.2 329.2 334.0 384.0 62.8 134.6 67.5 110.7 35.9 144.5 103.5 63.0 101.3 157.7 125.2 59.9 36.1 81.5 91.9 244.6 70.9 68.6 55.6 118.2 29.4 154.4 35.8 96.4 74.3 68.1 99.8 85.8 398.8 117.1 105.6 96.7 60.1 129.2 77.3 71.4 85.6 81.3 143.7 82.4 372.7 83.5 122.1 178.3 110.8 71.2 79.2 151.4 113.8 100.2 178.0 150.3 42.2 200.6 294.8 103.3 82.0 89.9 94.8 79.4 94.5 55.9 156.0 97.6 78.9 53.1 78.6 194.7 133.5 85.9 146.2 86.5 48.8 51.7 96.5 99.8 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.8;Cytotrophoblasts: 22.3;Extravillous trophoblasts: 21.0;Hofbauer cells: 14.8;Syncytiotrophoblasts: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" 27.1 31.8 19.6 20.0 18.9 21.5 28.8 12.0 21.3 45.4 14.2 29.6 31.3 43.2 20.7 26.5 38.2 23.0 28.5 19.9 19.7 29.5 57.9 25.0 19.8 17.0 16.0 49.6 56.8 46.2 48.4 25.7 18.5 39.1 19.1 22.4 64.8 34.2 9.4 26.9 30.3 25.6 13.8 22.3 39.5 21.4 17.0 18.0 42.0 9.8 15.6 31.8 31.4 17.0 28.6 37.2 22.7 39.7 51.7 34.3 42.3 33.4 56.6 25.5 30.2 11.3 49.1 24.5 69.4 49.8 32.9 39.0 22.9 31.0 11.8 35.8 23.0 24.8 20.6 28.8 74.8 29.4 28.6 41.7 33.1 33.7 68.5 50.2 24.9 38.4 37.3 40.9 25.3 53.9 13.7 19.8 17.8 41.8 24.1 31.1 34.2 74.8 29.3 17.6 24.8 38.2 25.2 65.3 52.8 21.5 56.6 42.9 22.0 44.3 24.7 28.7 22.1 59.0 37.0 18.8 56.7 44.7 62.5 3.1 5.7 7.6 7.8 8.4 7.2 6.7 8.2 7.8 9.7 6.3 7.9 7.0 0.9 9.4 8.1 8.9 9.4 7.2 19.6 18.9 12.0 21.3 19.9 19.7 17.0 16.0 18.5 13.8 17.0 17.0 5.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 22.3 0.4 0.0 0.0 0.0 RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 132.0" "Group enriched" "Detected in many" 10 "Cardiomyocytes: 2180.6;Excitatory neurons: 1320.5;Inhibitory neurons: 790.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.7;HEK 293: 8.5;K-562: 2.3;NB-4: 2.7;NTERA-2: 3.1;U-937: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA020028: AB_1856528" "unprognostic (5.23e-3)" "unprognostic (2.15e-2)" "unprognostic (5.02e-4)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (1.45e-3)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (0.00e+0)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" 0.7 0.7 9.1 0.8 15.9 0.0 0.6 8.7 24.0 1.5 0.0 2.0 0.2 0.7 0.4 2.9 0.7 1.9 132.0 10.5 0.0 0.1 0.1 1.8 0.1 0.0 0.0 2.9 8.4 0.0 1.8 1.2 0.0 2.9 0.5 6.5 0.5 1.7 0.1 0.3 0.5 0.7 0.0 1.3 1.5 1.1 0.0 0.1 4.4 0.3 0.0 1.2 0.4 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.9 0.3 0.0 0.0 7.7 8.5 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 2.3 0.4 0.0 0.0 0.0 2.7 3.1 0.6 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 9.1 15.9 8.7 24.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.2 0.0 0.5 17.0 0.0 0.4 0.0 0.0 0.0 74.2 0.3 0.1 2180.6 0.0 1.3 1.8 10.4 0.1 0.1 0.0 0.0 0.0 21.1 0.2 3.4 10.6 3.5 0.0 1320.5 2.9 0.1 53.6 0.0 0.5 0.0 0.5 1.1 0.0 0.1 1.7 790.6 0.0 0.0 0.0 0.2 15.3 1.2 1.3 8.8 48.7 0.0 1.3 0.0 29.7 140.6 0.4 0.0 0.0 0.1 0.0 1.0 0.2 0.7 5.3 0.0 0.5 21.6 5.8 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 SACM1L "KIAA0851, SAC1" ENSG00000211456 "SAC1 like phosphatidylinositide phosphatase" Q9NTJ5 3 45689056-45745409 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039573, HPA069869" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Golgi apparatus" "HPA039573: AB_10674983, HPA069869: AB_2686216" "unprognostic (2.07e-1)" "unprognostic (4.08e-1)" "unprognostic (1.36e-3)" "unprognostic (1.14e-1)" "unprognostic (2.31e-2)" "unprognostic (4.34e-2)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" "unprognostic (8.54e-2)" "unprognostic (1.94e-2)" "unprognostic (1.22e-2)" "unprognostic (6.29e-3)" "prognostic favorable (5.47e-7)" "unprognostic (3.50e-1)" "unprognostic (1.62e-1)" "unprognostic (2.50e-1)" "unprognostic (1.33e-2)" 23.5 26.3 13.2 26.2 13.8 21.1 22.0 17.1 16.1 22.1 13.6 24.0 23.3 20.6 23.3 20.2 16.9 19.2 16.3 14.0 18.8 38.1 28.2 28.9 26.8 15.5 14.9 16.2 21.8 35.8 10.9 25.0 14.7 24.3 23.6 20.3 22.9 20.6 8.8 18.4 21.6 21.2 14.6 26.2 25.0 14.2 15.9 32.5 43.5 11.4 25.0 22.9 10.8 16.3 31.0 23.0 38.0 22.0 58.8 39.2 29.6 50.1 43.0 36.9 33.1 30.5 21.8 47.8 24.3 39.8 49.8 22.7 50.4 27.0 48.9 34.3 26.8 50.8 38.2 25.7 37.6 78.0 61.5 26.5 41.1 39.9 29.6 29.9 25.6 43.2 57.9 45.7 60.6 14.0 59.5 41.4 40.1 29.6 40.1 17.2 20.0 48.4 41.2 42.7 15.0 36.1 35.5 36.3 44.7 38.0 31.0 64.1 33.7 36.2 21.1 37.0 44.5 25.3 71.7 32.5 45.1 106.8 36.2 10.3 17.1 27.5 24.6 14.2 27.5 11.0 17.8 26.0 27.2 11.9 17.6 23.5 14.1 65.2 13.0 11.1 16.7 27.6 13.2 13.8 17.1 16.1 14.0 18.8 15.5 14.9 14.7 14.6 15.9 16.3 18.4 28.9 37.3 22.5 22.2 19.6 9.1 14.6 22.2 22.8 15.2 12.3 16.6 14.3 15.7 7.3 31.3 22.9 55.4 16.4 19.6 11.1 1.6 15.9 31.9 17.6 12.0 23.4 44.7 10.0 11.2 19.5 17.3 18.5 17.1 17.2 17.2 15.4 24.5 33.7 42.7 9.4 18.3 23.0 18.7 2.9 16.8 22.6 17.8 30.9 25.5 15.8 46.4 40.7 43.6 12.9 20.7 23.0 33.2 14.6 18.5 22.3 14.1 20.7 6.6 15.8 16.6 12.3 12.0 15.7 17.3 18.3 44.5 19.5 13.6 11.6 SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "Rods & Rings" "HPA040400: AB_2676962" "unprognostic (1.11e-1)" "unprognostic (4.78e-2)" "unprognostic (4.27e-3)" "unprognostic (1.38e-3)" "unprognostic (7.86e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (8.03e-2)" "unprognostic (6.70e-3)" "unprognostic (1.06e-2)" "unprognostic (5.09e-2)" "unprognostic (3.88e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-1)" 139.9 294.5 208.6 169.1 228.0 253.0 169.9 187.2 246.6 153.8 196.2 143.0 123.9 152.1 408.6 91.0 205.9 182.1 151.8 234.6 308.8 205.2 302.3 167.5 218.9 214.0 258.8 255.7 231.4 236.5 138.9 309.2 247.6 228.2 143.5 219.1 212.9 172.7 111.1 70.8 140.5 139.1 219.5 159.0 161.1 104.3 290.5 243.4 245.4 129.0 186.5 141.0 64.0 218.5 119.9 112.4 147.9 79.9 209.3 149.8 69.7 139.2 247.0 128.5 173.7 72.2 139.9 80.9 183.5 156.0 134.7 97.7 100.8 112.4 146.9 33.6 49.5 112.2 87.3 119.2 189.6 48.8 130.6 175.2 260.0 121.6 125.5 257.4 192.0 150.7 128.4 191.2 142.9 74.2 128.4 88.8 96.0 253.6 61.3 98.7 88.4 107.4 220.3 100.4 48.6 162.5 140.6 160.5 208.2 115.7 112.2 93.3 144.0 89.6 230.5 35.0 56.5 103.4 110.6 81.0 215.8 118.4 146.5 964.6 252.9 443.1 321.2 253.2 364.8 233.1 473.0 377.9 247.0 302.4 776.2 543.6 478.1 258.8 335.3 212.0 483.8 920.3 208.6 228.0 187.2 246.6 234.6 308.8 214.0 258.8 247.6 219.5 290.5 218.5 179.8 169.9 147.6 79.0 458.5 0.0 331.6 0.0 154.8 291.5 247.8 166.2 135.4 261.7 82.3 211.5 123.0 235.9 566.8 142.2 127.2 387.5 629.8 235.9 114.8 170.8 115.3 145.4 128.0 358.9 254.5 181.7 170.7 133.6 223.3 325.7 240.2 273.4 292.0 139.7 157.8 122.0 0.0 448.6 0.0 908.1 218.7 387.9 0.0 60.9 298.5 317.2 358.4 82.9 111.7 250.1 137.0 294.2 505.1 280.7 252.6 289.7 212.1 252.5 177.5 203.7 177.1 194.7 133.9 133.4 0.0 276.9 794.4 167.8 115.9 310.6 SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" 43.1 46.7 27.8 40.3 32.8 51.5 40.7 31.9 31.2 40.5 38.8 76.0 75.7 36.9 36.9 103.4 47.4 35.4 32.4 26.1 29.8 44.9 42.0 49.6 47.9 40.7 30.9 26.5 54.5 85.6 29.4 48.9 36.7 35.5 72.7 4.7 92.7 32.4 34.2 68.3 80.1 33.6 33.6 66.8 64.9 36.2 33.3 33.0 38.3 18.9 53.4 38.1 49.4 35.4 44.7 57.3 24.2 37.6 72.0 37.2 72.0 45.0 56.6 46.9 50.1 83.0 102.6 36.5 57.8 68.1 67.7 157.8 72.3 55.9 19.4 145.8 71.1 92.8 31.2 57.6 54.3 48.0 170.9 48.0 97.6 44.4 32.0 37.0 46.0 42.0 31.3 67.5 33.3 68.1 24.6 55.3 24.1 111.0 36.6 42.6 22.3 126.4 54.0 63.1 24.9 25.0 36.7 64.3 42.4 35.4 88.5 76.3 43.4 40.2 23.9 43.8 53.0 46.1 73.2 37.6 37.8 112.2 30.2 118.3 111.3 90.0 94.1 106.9 76.1 80.8 85.3 95.9 81.8 70.9 69.4 75.8 74.4 83.8 119.3 128.7 105.3 120.8 27.8 32.8 31.9 31.2 26.1 29.8 40.7 30.9 36.7 33.6 33.3 35.4 36.0 73.7 31.7 17.9 49.5 17.5 41.7 40.5 19.4 6.8 28.0 24.8 14.4 24.3 53.1 40.5 2.1 156.9 63.4 116.8 15.6 67.4 132.3 30.8 22.0 36.2 37.3 29.0 7.7 92.8 61.9 37.2 54.0 40.6 79.2 31.3 26.4 27.7 164.7 6.7 6.1 77.5 42.7 78.3 44.5 56.2 32.0 77.0 32.0 21.5 56.9 41.4 63.8 12.1 17.9 96.1 75.5 23.0 73.1 54.0 105.7 48.1 52.6 8.4 26.3 25.6 35.8 47.1 35.3 39.6 22.3 136.4 55.1 40.0 64.2 58.5 SCAMP5 MGC24969 ENSG00000198794 "Secretory carrier membrane protein 5" Q8TAC9 15 74957219-75021495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 179.9;parathyroid gland: 103.1;retina: 283.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 113.3;Cone photoreceptor cells: 125.1;Enteroendocrine cells: 62.5;Excitatory neurons: 75.1;Horizontal cells: 70.7;Inhibitory neurons: 99.3;Rod photoreceptor cells: 168.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 27.7" "Lineage enriched" "Detected in single" 33 "dendritic cells: 27.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 88.1;SH-SY5Y: 49.3;THP-1: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046645 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA046645: AB_2679734" "unprognostic (1.37e-1)" "unprognostic (3.30e-1)" "unprognostic (1.80e-1)" "unprognostic (1.20e-2)" "unprognostic (2.74e-1)" "unprognostic (4.46e-2)" "unprognostic (2.56e-1)" "unprognostic (4.13e-1)" "unprognostic (2.34e-1)" "unprognostic (8.37e-2)" "prognostic favorable (5.67e-5)" "unprognostic (9.82e-2)" "prognostic favorable (1.34e-6)" "unprognostic (7.27e-2)" "unprognostic (3.01e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-2)" 3.0 20.6 106.7 4.3 125.2 2.6 3.1 75.1 179.9 2.8 12.5 5.8 41.6 5.7 3.6 1.5 5.0 5.6 5.5 128.7 74.8 16.7 4.2 2.8 7.9 113.9 67.4 6.0 53.4 103.1 67.7 6.7 112.5 4.6 4.9 283.7 7.2 2.7 0.6 2.1 30.4 3.2 35.8 8.5 15.6 10.7 80.6 4.4 6.5 0.8 10.0 5.9 1.8 124.4 1.5 17.8 3.8 12.6 0.3 0.2 0.5 0.4 0.6 4.0 1.4 4.9 8.9 28.0 8.5 1.1 3.3 1.2 15.6 1.1 1.4 4.4 2.0 3.5 2.1 25.8 2.7 0.4 11.5 1.3 2.1 1.0 0.3 2.8 1.7 10.1 0.2 22.1 1.0 15.1 1.1 10.2 13.4 2.1 7.1 0.4 3.2 6.7 1.0 8.6 88.1 49.3 19.8 13.6 27.6 2.7 7.7 34.0 1.1 1.2 8.2 1.6 1.3 1.8 2.4 2.6 3.0 21.2 4.3 0.6 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.8 0.4 0.1 27.7 0.0 0.4 106.7 125.2 75.1 179.9 128.7 74.8 113.9 67.4 112.5 35.8 80.6 124.4 2.2 0.0 1.1 14.7 2.5 0.3 0.5 0.4 2.8 113.3 3.2 2.7 3.0 7.2 0.4 5.5 125.1 0.1 35.5 2.9 1.9 4.4 0.5 0.4 0.7 3.6 62.5 0.0 75.1 43.3 0.3 1.9 12.8 0.3 0.0 4.1 6.8 0.6 13.8 70.7 99.3 5.0 0.0 6.9 0.2 0.7 2.1 2.0 1.8 6.5 0.4 29.9 0.0 32.2 26.2 6.8 5.3 6.4 8.9 0.8 34.0 13.0 2.7 168.0 0.0 0.9 2.8 1.8 4.7 1.7 0.1 0.1 0.6 2.0 2.7 0.3 SCAP KIAA0199 ENSG00000114650 "SREBF chaperone" Q12770 3 47413681-47477126 "Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Theca cells: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004713 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA004713: AB_1079868" "unprognostic (4.02e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (4.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.74e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-2)" "unprognostic (7.10e-2)" "prognostic favorable (7.14e-4)" "unprognostic (4.07e-2)" "prognostic favorable (4.33e-5)" "unprognostic (3.15e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-3)" 23.4 135.2 30.2 15.8 27.7 17.1 25.8 35.3 37.5 29.0 35.2 36.8 24.5 31.4 17.4 37.5 28.2 14.5 29.8 27.8 26.2 33.3 73.7 22.2 15.9 32.1 27.5 35.4 34.1 28.3 34.0 18.2 30.1 29.1 21.8 27.5 25.1 18.6 27.5 47.0 34.3 20.5 18.8 37.1 32.3 39.2 34.0 18.6 30.6 19.3 15.6 31.7 29.3 26.0 19.7 28.2 28.8 45.6 51.6 26.4 51.3 18.8 27.9 30.0 28.3 38.0 31.9 31.5 26.7 30.4 30.7 20.3 41.1 38.8 31.7 23.6 29.0 54.1 37.7 40.9 51.4 33.4 32.5 33.2 40.1 36.4 42.2 24.9 26.1 32.0 38.5 21.4 24.8 28.9 37.1 49.2 30.7 39.7 40.1 20.1 25.9 37.5 24.4 37.1 19.0 35.1 27.1 33.8 18.8 36.8 29.5 37.6 22.0 27.2 33.1 39.7 26.8 21.2 24.6 18.3 27.6 30.2 20.9 6.0 5.9 6.5 6.6 4.9 8.7 5.5 5.4 6.0 7.0 5.3 6.1 6.1 15.8 6.7 4.2 5.4 7.3 5.0 30.2 27.7 35.3 37.5 27.8 26.2 32.1 27.5 30.1 18.8 34.0 26.0 15.0 0.0 16.0 34.0 11.6 11.6 9.8 14.5 19.9 23.2 20.2 18.9 14.6 11.5 16.2 20.2 29.2 27.6 9.8 55.3 0.0 13.9 13.0 11.5 12.8 12.9 12.0 10.1 39.3 15.1 15.8 16.9 26.5 16.3 7.0 53.5 7.9 46.0 16.3 53.8 39.7 20.7 10.2 13.4 8.3 28.6 19.6 10.4 24.9 15.0 7.7 18.6 14.4 27.6 30.2 10.6 33.8 21.4 18.5 10.2 40.6 9.7 17.9 34.7 32.9 14.0 22.3 14.6 25.0 19.6 11.6 79.1 12.1 100.1 31.4 9.0 SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.7;brain: 353.6" "Cell type enhanced" "Detected in many" "Astrocytes: 248.4;Oligodendrocyte precursor cells: 892.7;Oligodendrocytes: 513.6" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 69.2;RPTEC TERT1: 90.1" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favorable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" 6.8 156.7 226.1 3.7 283.7 2.9 5.7 302.5 260.4 10.6 85.2 12.9 4.5 12.5 97.6 5.8 18.7 9.3 8.1 212.6 277.4 33.1 2.5 15.0 3.0 353.6 272.7 93.7 40.9 18.7 31.4 7.5 291.0 12.7 4.0 70.2 18.0 24.3 1.3 8.2 6.0 12.0 314.1 4.5 10.6 33.3 255.6 10.6 35.5 4.2 4.4 7.7 8.7 316.2 11.2 7.1 36.0 18.6 19.7 12.5 0.6 69.2 33.9 29.7 22.8 0.5 1.7 22.5 23.5 14.5 8.0 19.9 10.6 7.6 37.0 4.4 4.7 1.0 8.1 0.7 2.9 10.0 6.9 10.0 30.6 5.9 5.2 30.5 48.4 25.8 1.3 2.2 15.6 4.4 42.6 2.1 2.6 0.2 5.0 35.6 21.5 17.9 90.1 11.2 20.1 11.5 11.4 0.5 6.8 3.5 1.3 5.0 59.5 31.5 18.1 11.9 18.9 6.0 2.5 2.2 15.3 10.5 9.0 1.9 0.6 0.1 3.9 0.2 2.5 0.2 0.8 2.3 0.3 0.4 0.7 2.6 0.7 1.1 0.4 0.7 0.2 1.2 226.1 283.7 302.5 260.4 212.6 277.4 353.6 272.7 291.0 314.1 255.6 316.2 1.4 44.8 3.9 248.4 0.8 10.7 16.5 16.3 5.7 101.4 6.8 4.8 2.9 27.1 25.7 27.6 25.0 1.9 3.9 0.4 13.7 79.7 115.0 13.5 9.3 7.7 7.7 0.0 84.3 46.9 0.2 16.8 2.6 14.8 0.0 10.5 10.4 0.2 1.1 101.0 107.0 0.3 10.2 1.3 3.3 100.3 55.0 1.8 3.6 23.4 1.9 145.3 4.1 892.7 513.6 8.9 0.0 58.3 0.7 11.3 0.2 20.4 13.0 14.6 6.6 3.6 11.5 2.9 3.7 2.7 7.2 0.1 3.2 137.4 2.0 9.3 SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.0;Distal enterocytes: 230.9;Glandular and luminal cells: 189.8;Intestinal goblet cells: 180.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 300.5;HBEC3-KT: 202.4;hTCEpi: 85.3;RPTEC TERT1: 103.7;RT4: 114.1;SK-BR-3: 96.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" 3.4 12.5 0.2 5.6 0.1 0.5 20.6 1.1 0.2 64.7 113.6 66.4 18.7 7.6 43.2 140.1 57.9 17.7 0.7 6.8 0.0 148.5 8.2 62.9 0.2 0.1 0.3 3.5 40.0 0.7 16.6 0.4 0.1 43.7 65.4 0.0 157.3 49.5 0.5 54.6 26.0 2.9 0.1 0.7 63.6 4.7 1.3 1.9 94.3 0.1 12.5 20.8 57.6 0.1 21.6 4.1 0.0 1.9 0.3 0.4 17.6 0.0 0.1 0.1 0.0 6.1 300.5 0.3 0.8 0.1 0.1 14.0 0.0 202.4 0.0 0.0 0.0 0.0 17.5 3.1 20.9 0.0 0.1 5.1 85.3 0.0 61.6 0.4 0.0 0.5 0.0 0.1 0.5 1.9 0.1 0.3 17.6 38.9 0.8 0.2 0.0 0.5 103.7 114.1 1.2 0.1 2.3 96.7 0.1 17.1 22.3 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 1.5 0.0 0.0 1.0 0.5 0.1 0.2 0.1 1.1 0.2 6.8 0.0 0.1 0.3 0.1 0.1 1.3 0.1 1.7 73.7 75.7 0.0 1.3 1.9 25.1 17.0 10.8 0.9 17.7 21.2 0.8 54.3 52.5 114.0 4.2 1.4 1.8 230.9 5.9 45.0 0.5 85.3 17.8 3.2 27.1 0.0 0.3 33.9 0.3 2.0 97.3 189.8 2.5 1.3 1.4 3.2 0.3 1.7 0.2 180.3 63.1 1.9 3.1 0.6 1.8 2.5 0.0 0.0 1.6 0.3 1.0 0.5 0.1 39.4 95.8 1.5 0.3 30.9 12.2 6.2 36.7 1.4 0.0 5.6 4.3 1.2 3.7 48.1 8.8 1.6 3.6 0.2 31.5 42.1 SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.8;intestine: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Club cells: 64.8;Collecting duct cells: 57.0;Distal enterocytes: 262.8;Ionocytes: 107.8;Paneth cells: 73.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 33.3;RPMI-8226: 9.2;RT4: 18.5;U-266/70: 55.4;U-266/84: 20.2" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" 18.5 0.4 0.0 1.1 0.0 0.2 17.7 1.0 0.0 48.5 0.0 94.2 2.5 2.8 0.1 82.8 3.7 0.5 0.3 0.0 0.0 31.7 0.2 23.9 0.8 0.0 0.0 0.7 2.1 0.3 1.0 3.6 0.1 10.5 35.6 0.0 39.5 2.4 1.4 36.0 4.3 0.8 0.0 3.7 24.1 0.3 0.0 0.7 9.2 0.8 5.4 8.3 56.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 9.2 0.0 18.5 0.2 0.0 0.0 0.5 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 55.4 20.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.7 99.3 28.3 0.0 7.1 3.1 15.4 27.8 5.7 0.0 4.4 3.0 0.7 0.0 64.8 57.0 0.0 0.7 0.1 262.8 0.0 0.0 0.1 11.9 1.6 6.2 7.7 0.0 0.3 0.4 0.3 1.0 36.7 23.4 8.2 0.0 1.1 0.1 0.1 0.0 0.3 21.4 107.8 0.0 0.0 0.2 0.0 1.0 10.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 73.7 0.0 38.7 6.1 0.0 0.1 9.2 0.0 0.0 0.1 0.7 0.1 0.4 29.8 5.4 2.2 1.4 0.0 15.2 19.7 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.6;pancreas: 68.2" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 54.4;Ductal cells: 92.0;Exocrine glandular cells: 93.8;Pancreatic endocrine cells: 41.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "basophil: 1.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.5" "Cell line enriched" "Detected in single" 5 "Karpas-707: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007269 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" 0.3 0.4 0.3 0.2 0.3 0.3 0.0 0.6 1.2 0.0 0.3 0.1 26.6 0.2 0.2 0.3 0.4 0.4 0.3 0.4 0.4 12.5 0.4 8.6 0.1 0.3 0.2 0.4 68.2 0.1 0.2 0.1 0.4 0.0 0.0 2.4 0.0 0.0 0.2 0.2 3.8 0.0 0.2 0.3 4.5 0.5 0.6 0.1 0.9 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.6 1.2 0.4 0.4 0.3 0.2 0.4 0.2 0.6 0.4 0.0 0.0 54.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.4 0.0 1.8 5.5 0.0 0.0 0.0 0.1 11.7 92.0 4.5 0.0 0.2 0.1 2.4 0.0 3.0 93.8 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.7 5.0 4.1 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 1.0 1.6 0.3 0.0 0.0 0.7 41.9 0.0 0.0 0.0 0.1 0.1 0.5 0.0 1.9 0.0 0.0 0.6 0.3 0.9 0.0 0.0 0.3 0.4 0.0 0.1 0.0 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 142.9 138.1 66.2 83.4 69.4 172.2 136.2 69.0 80.4 147.1 76.6 110.8 82.9 111.0 202.5 81.6 103.6 97.5 98.4 63.7 72.6 137.2 152.3 107.9 112.6 74.1 67.2 168.6 139.4 114.6 84.5 115.1 73.9 82.0 124.9 37.0 95.9 87.5 154.3 70.5 86.4 96.3 72.4 86.2 95.3 61.5 69.4 93.2 177.5 147.4 98.2 137.3 94.0 75.3 201.7 320.7 286.7 425.4 368.5 462.8 225.4 310.1 356.5 241.9 291.2 347.1 443.0 99.0 198.8 370.3 277.2 408.3 409.1 243.4 255.5 267.1 239.4 279.4 358.8 324.9 311.7 213.4 281.2 315.8 305.0 169.1 285.1 366.0 337.9 116.7 295.8 244.3 315.1 363.1 89.2 345.8 282.1 266.2 135.4 101.6 368.4 302.9 472.6 424.4 131.2 300.8 257.3 239.5 598.5 407.0 248.5 416.6 254.3 240.0 181.0 209.8 361.9 224.4 509.6 150.0 226.4 331.7 180.6 83.5 161.1 89.7 95.1 173.7 95.0 101.0 114.8 104.7 165.8 90.0 95.1 98.0 111.6 134.3 184.8 160.9 168.8 200.8 66.2 69.4 69.0 80.4 63.7 72.6 74.1 67.2 73.9 72.4 69.4 75.3 261.1 89.8 99.1 25.8 131.8 107.1 179.4 356.6 90.5 30.0 163.7 202.6 68.2 228.8 188.0 128.8 22.9 309.1 171.9 111.1 238.7 258.8 46.3 118.5 268.0 217.2 157.4 101.7 21.2 247.3 655.3 206.0 120.8 184.1 218.4 191.0 197.7 165.5 363.3 20.2 22.8 218.7 168.9 386.7 337.2 100.6 299.5 337.3 158.3 24.4 396.7 110.5 204.9 26.7 38.3 183.4 136.3 166.3 197.9 185.7 142.7 350.9 99.3 38.2 170.9 173.5 225.5 233.5 169.6 135.2 119.9 305.8 153.4 237.6 210.7 242.2 SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" 82.1 100.7 31.3 88.3 33.4 79.5 75.3 33.5 34.7 144.5 52.4 90.7 81.9 88.9 128.9 88.7 78.1 81.7 74.2 32.3 39.6 64.6 134.8 93.3 60.2 40.9 37.6 67.3 272.1 111.7 93.5 112.8 36.0 90.0 90.0 37.0 176.3 97.0 70.5 66.9 75.8 110.7 36.6 73.7 105.5 38.8 46.6 61.4 104.8 59.3 80.6 97.0 68.7 35.8 272.8 136.5 132.0 240.3 367.9 317.3 256.9 426.9 470.8 349.0 371.2 259.1 186.9 184.7 259.5 534.8 266.2 232.6 209.0 291.3 334.2 168.1 126.2 213.5 143.5 273.6 542.9 264.1 225.9 348.1 345.4 329.3 422.4 265.0 314.3 122.2 136.9 415.3 412.8 237.7 135.1 87.5 184.6 231.6 202.8 144.2 125.5 349.8 181.4 229.3 155.8 162.4 216.0 193.5 270.7 152.0 184.2 215.1 327.3 278.3 164.7 333.7 201.4 386.6 210.6 265.8 456.3 166.2 369.1 160.3 88.6 67.0 89.0 79.6 120.0 43.8 62.9 78.2 82.6 26.1 38.8 46.2 22.5 65.0 84.2 114.0 45.1 116.9 31.3 33.4 33.5 34.7 32.3 39.6 40.9 37.6 36.0 36.6 46.6 35.8 31.9 32.1 33.1 18.6 46.6 37.0 25.7 44.4 30.7 17.0 63.5 41.3 15.0 37.1 43.3 49.7 35.5 64.3 59.2 107.2 3.9 81.0 42.2 28.2 72.9 45.9 73.6 19.5 12.6 154.5 136.3 57.4 77.5 68.6 26.0 55.6 49.6 118.2 75.9 26.9 18.5 150.8 38.7 34.8 32.1 25.7 41.0 38.2 33.8 26.2 32.1 22.4 28.8 19.1 17.2 104.9 50.2 43.6 192.8 69.6 63.5 26.8 31.0 15.5 32.9 25.6 47.2 12.3 18.4 42.5 29.5 127.9 32.4 52.6 100.4 44.6 SEC61A2 FLJ10578 ENSG00000065665 "SEC61 translocon subunit alpha 2" Q9H9S3 10 12129637-12169961 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 41.2;Horizontal cells: 35.3;Inhibitory neurons: 42.4;Late spermatids: 31.1;Oligodendrocytes: 44.2;Spermatocytes: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.83e-2)" "unprognostic (2.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.01e-3)" "unprognostic (4.18e-2)" "unprognostic (1.84e-2)" "unprognostic (1.28e-3)" "unprognostic (1.55e-2)" "unprognostic (2.97e-1)" "unprognostic (3.95e-2)" "prognostic favorable (1.08e-5)" "unprognostic (3.14e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (6.41e-2)" "unprognostic (4.95e-2)" "unprognostic (6.18e-2)" "prognostic favorable (8.75e-4)" 4.2 4.8 24.0 4.9 23.2 15.1 4.5 18.3 27.6 8.2 8.0 7.0 3.4 6.9 7.9 4.1 6.6 4.5 9.9 24.1 25.9 5.8 12.6 5.2 5.6 21.1 24.1 7.1 4.2 3.8 13.1 4.0 24.4 7.5 5.0 18.9 4.5 5.1 7.8 8.2 5.9 5.0 18.8 7.2 4.9 15.2 22.5 6.2 5.9 7.1 5.4 6.2 6.5 28.9 8.4 13.2 19.2 12.0 7.3 5.0 6.3 8.6 4.6 15.4 16.1 13.3 5.7 3.4 4.4 12.3 20.1 7.2 24.9 10.4 13.2 9.7 10.2 4.0 19.7 9.7 7.6 2.5 9.1 7.2 6.4 27.2 4.5 7.2 4.1 18.7 4.7 9.1 12.9 7.2 8.1 4.2 18.4 6.9 4.4 8.7 7.2 2.0 9.8 8.8 8.6 13.2 11.7 6.3 6.1 14.3 12.3 4.1 7.9 13.5 15.3 17.8 5.9 8.4 12.4 5.2 10.6 3.2 4.1 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.5 0.5 0.3 0.5 1.0 0.7 1.7 0.9 0.2 2.5 0.7 0.1 24.0 23.2 18.3 27.6 24.1 25.9 21.1 24.1 24.4 18.8 22.5 28.9 2.4 3.2 2.8 19.2 6.3 1.8 2.6 2.5 2.2 14.6 2.8 1.9 7.3 1.5 3.3 9.2 8.4 3.4 7.5 3.7 0.0 2.8 19.8 6.2 5.8 2.6 1.2 3.6 41.2 2.3 2.3 4.9 3.1 4.2 2.5 5.6 3.9 14.1 2.9 35.3 42.4 2.2 6.1 1.9 2.3 31.1 6.8 2.6 5.4 15.0 1.4 5.8 2.1 26.2 44.2 2.0 2.8 4.5 5.0 3.0 1.3 1.4 4.2 15.9 0.0 2.7 4.8 35.2 14.3 1.7 1.4 3.4 4.9 2.8 1.0 2.0 SEC62 "Dtrp1, HTP1, TLOC1" ENSG00000008952 "SEC62 homolog, preprotein translocation factor" Q99442 3 169966635-169998373 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014059, HPA061450" Approved Approved "Endoplasmic reticulum,Intermediate filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "Intermediate filaments" "HPA014059: AB_1858029, HPA061450: AB_2684524" "unprognostic (8.15e-2)" "unprognostic (6.84e-2)" "unprognostic (2.72e-1)" "unprognostic (4.93e-3)" "unprognostic (5.13e-1)" "unprognostic (1.10e-3)" "unprognostic (1.24e-1)" "unprognostic (4.04e-1)" "unprognostic (6.78e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" 104.9 86.5 82.9 58.6 94.3 94.4 64.5 88.1 120.6 74.4 74.6 60.9 58.5 74.7 131.9 44.4 52.3 58.5 49.1 81.8 108.1 118.6 193.7 67.6 63.3 94.9 97.7 75.9 116.5 109.7 41.5 71.0 97.9 82.5 56.6 128.9 130.4 83.5 55.3 27.4 59.4 68.3 95.5 83.5 91.1 34.6 92.3 51.1 120.9 60.2 67.0 63.7 31.7 99.9 140.4 96.6 74.2 66.3 217.9 114.7 46.7 175.5 128.3 80.0 82.5 104.0 143.9 156.8 190.7 125.9 132.5 130.3 92.3 84.8 124.7 123.1 89.2 108.6 57.2 105.6 157.9 111.6 68.5 115.0 79.7 88.0 85.3 108.8 80.1 47.3 68.0 147.2 96.3 117.2 58.9 59.0 76.4 110.8 62.5 77.6 107.6 212.8 115.1 88.5 76.1 71.9 143.7 155.8 125.3 71.3 233.5 101.0 107.8 113.1 51.0 95.6 143.1 168.8 134.9 240.8 118.5 85.1 108.0 17.2 34.8 62.3 44.2 37.1 49.2 77.6 40.6 43.5 30.9 82.1 50.9 46.6 52.0 31.8 29.0 35.1 39.1 27.6 82.9 94.3 88.1 120.6 81.8 108.1 94.9 97.7 97.9 95.5 92.3 99.9 419.0 237.2 291.5 64.6 362.7 254.4 252.8 511.1 144.0 362.0 223.3 278.5 582.1 320.3 431.7 680.5 277.3 218.7 209.5 144.7 195.6 256.4 31.6 302.9 424.8 363.7 261.1 874.1 79.3 347.6 215.0 396.3 104.5 455.3 293.5 105.2 463.7 1081.6 214.7 452.6 86.8 285.4 364.2 237.2 268.0 43.4 560.1 208.4 279.3 48.7 280.0 486.8 183.4 47.3 103.1 283.4 217.4 435.6 469.8 223.5 233.7 416.9 385.8 418.4 295.9 358.9 423.4 206.5 142.2 90.2 172.3 434.1 205.5 175.9 182.2 176.8 SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" 27.5 33.0 11.6 22.0 14.3 32.9 23.3 14.4 12.9 30.2 25.7 19.2 16.8 25.2 29.6 19.5 21.8 22.0 19.0 12.4 15.3 20.0 46.6 21.7 16.7 13.3 12.0 40.4 61.2 31.7 14.4 20.9 14.2 27.7 18.6 21.2 77.8 23.3 14.3 15.5 18.0 22.2 12.3 16.1 23.1 33.0 12.1 22.6 52.1 14.1 17.3 21.8 14.0 17.7 28.5 17.1 46.0 57.6 47.1 55.2 41.4 59.2 65.0 27.8 39.2 30.8 34.6 52.8 49.4 53.7 34.4 40.9 32.3 38.3 42.5 63.8 35.7 57.2 25.2 31.6 73.2 65.9 32.5 43.5 61.4 44.5 97.6 50.0 39.3 31.7 48.5 82.8 57.7 22.7 20.6 29.5 36.4 30.0 18.1 65.2 54.4 43.7 33.5 37.1 40.3 45.7 32.9 48.8 59.1 31.2 34.9 95.8 42.5 41.6 25.8 42.2 46.6 31.4 25.0 52.9 45.9 56.4 48.7 5.6 5.2 5.0 4.8 4.7 7.5 4.4 3.9 3.9 5.4 4.0 4.3 3.4 1.7 7.1 9.8 6.9 2.2 3.5 11.6 14.3 14.4 12.9 12.4 15.3 13.3 12.0 14.2 12.3 12.1 17.7 55.6 118.6 143.3 38.2 64.4 85.0 70.5 90.9 42.7 57.7 67.8 54.2 78.8 81.5 125.5 53.3 39.6 80.8 71.6 39.2 11.7 86.0 40.3 48.7 102.8 61.6 53.5 31.5 52.5 125.4 96.4 107.1 46.9 54.8 68.9 84.8 59.6 126.7 62.7 47.1 50.8 80.0 83.4 56.7 78.9 23.9 106.2 54.8 80.0 42.2 54.3 61.0 59.8 60.3 64.8 81.9 53.5 118.8 144.6 91.1 37.2 38.4 116.7 49.9 46.0 108.2 77.2 143.1 75.0 44.7 80.0 91.0 52.3 354.8 60.8 73.8 SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 403.4" "Cell type enhanced" "Detected in all" "Plasma cells: 238.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 339.5;U-266/84: 313.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA024267: AB_1856659" "unprognostic (4.94e-1)" "unprognostic (8.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-2)" "unprognostic (1.16e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-1)" "unprognostic (9.97e-2)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" "unprognostic (4.86e-1)" "unprognostic (3.31e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-2)" "unprognostic (1.25e-2)" 30.6 19.1 13.9 31.1 17.8 17.7 25.2 17.0 17.0 21.4 11.5 35.7 36.7 24.2 18.1 16.8 17.1 22.0 22.8 14.5 17.4 28.8 66.6 27.6 21.6 18.9 16.7 17.1 403.4 29.9 8.7 38.4 19.3 31.6 31.8 15.7 19.6 22.8 22.2 15.5 32.5 28.1 18.4 30.6 35.0 11.2 17.6 17.8 54.3 21.1 29.3 29.0 12.1 25.9 35.3 69.3 27.4 35.5 60.2 58.6 48.5 54.6 52.3 31.2 33.0 26.6 53.7 36.0 58.8 63.2 38.1 32.8 19.2 30.6 56.1 56.0 13.6 26.3 21.7 33.2 86.0 53.6 60.3 47.8 72.0 31.4 68.0 45.9 51.7 29.5 16.2 195.2 38.6 42.7 30.6 15.1 8.7 58.7 29.6 21.2 38.9 28.4 24.0 54.1 15.5 25.7 42.7 39.4 44.9 23.5 68.5 35.5 86.8 87.7 49.0 49.2 34.1 339.5 313.1 35.4 96.5 24.1 34.4 31.5 19.7 24.8 16.8 25.6 13.7 14.2 12.9 13.4 18.9 13.1 12.0 12.9 45.7 16.7 22.5 13.7 14.0 14.5 13.9 17.8 17.0 17.0 14.5 17.4 18.9 16.7 19.3 18.4 17.6 25.9 51.6 12.8 35.2 27.1 44.8 26.8 19.0 27.1 15.9 23.5 31.5 18.9 67.0 32.9 24.9 27.6 31.3 23.5 44.1 48.8 5.9 24.1 3.5 21.1 48.9 40.0 21.6 15.4 35.9 45.6 21.9 44.7 37.8 28.0 34.2 32.0 38.9 125.7 31.9 30.3 35.2 38.9 50.8 58.1 40.4 5.4 23.6 47.6 53.4 29.0 39.7 18.3 30.9 42.3 70.7 40.1 33.1 28.2 238.9 40.0 34.8 20.2 27.8 18.3 46.0 28.5 51.8 14.0 18.8 16.0 26.1 41.9 32.9 38.9 32.0 33.9 SEL1L3 KIAA0746 ENSG00000091490 "SEL1L family member 3" Q68CR1 4 25747433-25863760 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 128.3" "Cell type enhanced" "Detected in many" "B-cells: 114.7;Oligodendrocyte precursor cells: 128.7;Plasma cells: 271.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 82.1" "Group enriched" "Detected in many" 4 "memory B-cell: 42.0;naive B-cell: 41.8;plasmacytoid DC: 38.2" "Group enriched" "Detected in many" 4 "B-cells: 42.0;dendritic cells: 38.2" "Cell line enhanced" "Detected in many" "Daudi: 287.9;OE19: 217.9;U-698: 187.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 100.4" "HPA040045, HPA058792" Approved Enhanced Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA040045: AB_10796116, HPA058792: AB_2683822" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (3.06e-3)" "unprognostic (1.44e-2)" "unprognostic (2.43e-3)" "unprognostic (1.80e-1)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.33e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (5.11e-1)" "unprognostic (4.77e-2)" "unprognostic (7.21e-3)" "unprognostic (1.32e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 9.3 5.5 8.7 61.5 11.3 13.6 9.3 82.1 11.1 54.0 8.7 72.1 82.0 7.9 68.8 8.7 11.0 53.6 5.3 12.5 4.2 14.5 11.6 40.7 124.8 2.8 5.2 5.6 48.5 45.5 3.7 37.5 4.7 18.9 68.8 35.2 38.3 4.0 2.9 2.9 72.4 7.8 2.9 63.2 104.8 6.6 8.2 18.7 10.9 2.8 128.3 42.4 2.2 5.9 21.5 23.0 16.7 5.6 2.7 3.3 2.6 10.4 28.3 7.9 25.2 14.6 97.0 287.9 48.9 72.0 66.7 13.3 12.4 45.1 10.6 15.7 7.2 3.3 35.4 19.6 70.0 40.1 2.0 5.7 35.8 27.8 10.9 31.3 105.7 5.8 19.3 0.3 5.6 16.2 0.1 2.8 48.2 217.9 20.1 1.5 91.3 40.6 60.9 71.2 41.0 8.0 69.2 1.0 7.1 23.0 3.3 49.0 46.6 0.5 32.6 0.6 30.6 1.8 0.5 187.9 125.0 16.7 19.3 0.9 0.2 0.0 5.7 0.0 6.8 42.0 7.0 6.4 1.4 41.8 3.0 4.8 0.7 8.0 0.3 38.2 9.6 3.3 8.7 11.3 82.1 11.1 12.5 4.2 2.8 5.2 4.7 2.9 8.2 5.9 13.2 12.8 36.0 57.1 114.7 0.9 3.4 16.8 1.2 4.0 1.6 0.9 1.8 61.5 51.9 3.7 0.0 30.7 71.0 46.3 0.0 64.9 60.8 6.0 1.5 11.5 11.5 10.5 40.1 33.2 1.3 2.5 71.9 19.3 2.5 3.4 13.6 4.2 4.9 0.0 26.6 92.6 22.4 23.1 4.6 78.3 1.5 14.4 8.8 4.7 14.6 33.2 10.3 128.7 1.4 38.3 22.6 0.4 271.7 13.6 46.9 10.7 24.2 32.8 0.0 0.8 4.7 0.7 2.5 0.7 1.6 16.4 27.8 0.2 36.8 6.1 SEZ6 ENSG00000063015 "Seizure related 6 homolog" Q53EL9 17 28954901-29006440 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 54.7;pituitary gland: 15.8;retina: 27.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 58.7;Cone photoreceptor cells: 47.9;Excitatory neurons: 15.9;Horizontal cells: 43.7;Inhibitory neurons: 24.6;Rod photoreceptor cells: 18.2" "Cancer enriched" "Detected in many" 11 "glioma: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.1;neutrophil: 2.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011777 Enhanced NA NA 310000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA011777: AB_1856758" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (5.75e-3)" "unprognostic (5.33e-3)" "unprognostic (1.84e-2)" "unprognostic (1.76e-3)" "unprognostic (2.82e-2)" "unprognostic (2.22e-2)" "unprognostic (3.07e-1)" "unprognostic (4.75e-2)" "unprognostic (1.22e-3)" "unprognostic (3.15e-3)" "unprognostic (3.63e-6)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" 0.1 0.6 48.4 0.2 54.7 0.4 0.0 50.8 36.3 0.0 5.5 0.9 1.0 0.0 0.3 0.0 0.0 0.0 0.1 36.3 25.0 0.1 0.0 0.1 0.0 20.4 33.0 0.1 0.6 0.0 15.8 0.0 53.5 0.2 0.5 27.0 0.0 0.1 0.2 0.2 0.5 0.1 13.7 0.1 0.5 0.5 25.4 0.0 0.1 0.0 0.0 0.1 0.0 21.1 0.0 0.4 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.1 0.1 0.1 0.0 0.0 53.5 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.1 1.1 0.2 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.2 2.0 0.1 0.2 0.3 0.0 0.1 48.4 54.7 50.8 36.3 36.3 25.0 20.4 33.0 53.5 13.7 25.4 21.1 0.4 0.0 0.0 3.3 0.9 0.4 0.7 0.0 0.0 58.7 0.1 0.1 0.6 1.5 0.0 0.0 47.9 0.3 5.0 0.3 0.0 0.2 0.1 0.1 0.2 0.7 7.3 0.0 15.9 0.4 0.3 0.3 0.0 0.2 8.9 1.0 0.4 0.0 0.2 43.7 24.6 0.1 0.0 1.9 1.0 0.4 0.9 1.1 0.0 4.7 5.0 6.1 5.2 3.5 4.7 0.5 0.1 0.0 0.1 0.8 0.7 0.1 0.0 18.2 0.0 0.9 0.3 1.3 1.8 0.0 0.0 0.3 1.4 0.2 0.6 0.2 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SFT2D2 "dJ747L4.C1.2, UNQ512" ENSG00000213064 "SFT2 domain containing 2" O95562 1 168225938-168253021 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 142.6;Late spermatids: 142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 53.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042207 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042207: AB_10794789" "unprognostic (4.34e-1)" "unprognostic (8.62e-2)" "unprognostic (1.78e-1)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (8.62e-3)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.37e-1)" "unprognostic (1.91e-1)" "unprognostic (8.54e-2)" "unprognostic (4.00e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-2)" "unprognostic (2.15e-3)" "unprognostic (9.22e-2)" "unprognostic (1.22e-3)" "unprognostic (1.71e-1)" 7.2 6.2 11.0 6.7 11.1 32.3 10.3 6.4 8.3 9.1 8.7 8.0 4.9 17.7 7.1 13.2 8.2 6.1 5.2 11.4 10.0 8.4 9.7 8.7 10.6 14.3 10.2 14.6 6.2 6.8 12.4 5.0 12.4 6.5 8.1 3.0 11.6 4.7 3.8 15.3 9.0 10.0 8.8 11.0 6.8 18.5 11.7 8.4 6.5 3.5 11.3 5.4 8.6 15.2 15.6 19.4 7.7 14.2 22.0 12.4 15.8 10.7 7.9 8.3 9.3 20.7 15.6 13.9 16.1 15.8 7.5 51.3 13.2 11.9 11.1 19.4 4.9 10.3 26.3 15.0 11.8 17.3 15.7 14.5 8.9 11.0 9.8 6.4 11.6 18.9 9.8 17.8 9.5 6.5 15.0 12.8 9.2 23.1 4.4 16.4 10.6 10.8 12.3 18.4 4.9 9.4 13.4 16.8 14.6 12.5 13.4 15.4 12.8 10.8 8.2 11.6 14.3 6.8 13.5 20.6 8.6 12.1 11.6 20.6 12.1 4.4 8.9 22.0 5.2 7.3 5.2 5.8 16.9 6.9 4.8 5.5 5.7 7.1 27.5 53.2 6.4 8.1 11.0 11.1 6.4 8.3 11.4 10.0 14.3 10.2 12.4 8.8 11.7 15.2 22.3 44.8 33.1 3.3 43.4 28.0 16.2 30.0 23.3 0.7 39.7 37.3 5.1 25.8 39.1 38.6 4.2 9.5 142.6 63.9 1.9 23.6 65.7 64.2 45.6 32.9 31.8 31.6 1.2 20.5 26.4 44.9 32.1 86.1 49.4 35.7 33.5 54.3 45.5 3.3 0.3 24.8 18.3 99.4 77.3 142.5 24.2 60.5 42.7 13.1 58.5 11.3 40.2 3.0 9.4 37.0 21.4 33.8 23.0 33.0 36.8 37.3 46.6 6.5 26.3 25.7 22.2 30.6 10.1 44.8 48.3 9.9 38.2 23.4 28.6 23.0 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.6" "Cell type enhanced" "Detected in many" "Astrocytes: 405.2;Early spermatids: 96.4;Late spermatids: 168.4" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" 3.2 11.7 52.1 4.6 45.5 13.7 2.5 40.0 63.6 3.2 21.9 6.1 6.9 3.1 16.6 3.1 4.2 4.0 3.5 48.0 45.2 11.4 29.4 3.6 3.9 51.5 49.2 2.6 2.4 2.0 3.5 3.7 41.4 4.2 5.7 6.2 2.2 4.5 7.7 4.5 6.5 3.9 42.6 5.6 4.6 2.4 57.0 4.9 3.7 4.6 3.0 3.8 2.3 37.4 4.2 9.1 13.7 11.5 3.0 5.0 5.4 8.4 5.4 13.3 6.9 13.7 10.7 2.3 8.8 8.9 9.2 3.7 10.8 11.1 6.0 10.2 6.7 10.7 11.0 18.7 4.4 5.9 11.1 5.8 3.5 9.0 1.1 4.9 7.4 3.2 9.5 2.9 4.3 8.7 1.5 9.5 17.1 8.1 6.6 10.6 12.2 3.1 8.1 10.5 9.0 2.7 8.6 4.3 3.5 7.7 2.2 5.3 6.8 4.1 13.5 6.1 10.2 4.0 4.1 3.1 15.0 10.3 5.3 4.7 6.0 3.5 0.6 2.6 0.9 1.6 0.3 0.7 2.7 2.4 0.4 0.5 4.6 4.3 3.2 1.9 0.7 1.7 52.1 45.5 40.0 63.6 48.0 45.2 51.5 49.2 41.4 42.6 57.0 37.4 7.1 0.0 4.4 405.2 4.8 4.7 4.3 7.6 4.6 26.8 6.9 5.5 5.8 7.2 4.8 36.8 33.3 12.4 6.8 18.4 3.9 5.1 96.4 5.1 13.1 7.6 13.8 13.7 84.4 9.1 2.4 8.9 9.2 11.2 0.0 42.8 9.3 61.3 12.4 20.2 57.4 8.6 2.0 8.7 9.6 168.4 10.5 9.6 8.8 43.1 19.7 65.8 10.3 40.2 29.9 8.0 6.5 11.3 7.1 3.6 17.5 22.2 3.2 42.3 13.1 12.2 8.8 11.2 15.7 7.3 9.2 4.2 6.3 15.9 8.8 2.3 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SGSM3 "DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3" ENSG00000100359 "Small G protein signaling modulator 3" Q96HU1 22 40370591-40410289 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 176.4;Intestinal goblet cells: 135.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048980 Approved Supported "Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA048980: AB_2680585" "unprognostic (4.63e-2)" "unprognostic (7.51e-3)" "unprognostic (3.02e-2)" "prognostic favorable (4.47e-5)" "unprognostic (1.81e-1)" "unprognostic (6.83e-3)" "unprognostic (5.70e-3)" "unprognostic (7.53e-2)" "unprognostic (3.57e-1)" "unprognostic (5.67e-2)" "unprognostic (1.71e-3)" "unprognostic (1.93e-1)" "unprognostic (2.97e-1)" "unprognostic (4.08e-3)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.98e-3)" 24.8 42.6 34.6 26.1 34.8 19.3 29.4 27.3 43.6 37.3 32.6 46.6 32.8 31.9 14.5 49.2 37.1 28.7 37.0 33.2 33.3 36.4 37.3 33.8 32.9 36.5 34.3 30.8 107.7 24.7 55.0 21.9 34.8 62.6 24.3 11.0 70.1 25.9 34.2 36.7 46.1 17.4 27.6 51.5 91.4 39.8 33.6 27.5 48.7 23.4 28.3 33.1 35.6 31.9 37.8 21.1 30.6 34.1 33.2 18.1 43.4 35.0 22.9 26.0 33.7 12.0 30.9 23.3 23.7 37.9 15.6 30.0 29.2 42.9 10.4 58.4 68.8 15.9 56.9 11.3 31.6 23.1 33.1 30.2 29.5 29.1 17.4 29.2 46.0 48.6 19.8 31.4 19.4 60.5 32.1 23.5 20.5 75.8 14.0 59.3 19.3 51.1 26.8 33.0 18.8 24.2 38.6 55.4 27.5 24.2 46.3 38.9 40.2 8.8 31.8 23.4 20.6 47.1 23.2 31.0 37.4 19.0 22.9 1.1 14.6 16.3 18.7 15.7 15.6 17.7 11.5 14.9 18.9 22.3 13.8 11.3 3.3 35.4 11.9 31.6 11.7 15.8 34.6 34.8 27.3 43.6 33.2 33.3 36.5 34.3 34.8 27.6 33.6 31.9 5.3 3.2 10.3 14.0 32.8 11.5 32.4 33.1 14.8 57.0 12.1 7.1 8.3 27.1 42.1 7.3 18.8 42.8 23.9 46.4 1.9 20.2 17.5 5.1 3.8 14.3 31.3 18.1 27.1 45.3 54.3 14.0 176.4 6.7 15.9 3.1 21.8 24.0 24.2 26.9 34.6 135.3 50.8 17.2 8.3 31.7 22.7 11.8 16.0 13.1 21.6 13.4 30.9 15.6 15.1 21.3 40.6 19.2 30.5 46.1 36.2 4.4 60.2 34.0 39.5 14.4 13.8 83.5 44.4 19.8 10.4 45.6 16.7 3.3 47.7 60.0 SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146521964 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Microglial cells: 50.6;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039996: AB_10673266" "unprognostic (9.44e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (2.79e-1)" "unprognostic (6.69e-2)" "unprognostic (9.57e-2)" 5.4 4.6 2.6 4.9 4.0 6.0 6.0 3.2 2.6 7.2 1.7 7.0 4.6 4.9 12.0 5.8 4.4 5.6 2.9 2.9 3.6 3.8 7.2 5.9 5.6 4.6 3.8 5.6 6.5 3.7 3.6 8.9 4.9 6.3 9.2 3.9 6.9 3.3 2.2 3.7 5.4 5.9 3.8 5.3 9.7 3.4 3.5 6.5 7.0 3.2 5.9 4.7 4.8 5.1 5.2 1.7 12.2 5.0 8.6 10.3 5.8 6.3 8.2 5.7 5.8 4.7 21.6 9.6 4.4 6.9 3.6 5.2 7.2 8.6 6.8 11.1 3.5 11.8 4.2 8.5 5.5 20.5 18.3 4.9 6.8 6.9 8.7 3.1 10.2 10.2 13.2 25.6 4.3 3.6 15.6 5.2 2.2 11.4 8.6 8.6 8.9 13.7 4.0 3.8 3.7 3.1 4.3 12.8 5.3 6.4 7.5 8.1 5.8 5.1 5.4 7.8 4.4 20.7 24.9 13.4 7.0 8.2 7.4 10.9 3.0 4.5 3.7 4.8 3.8 3.9 3.7 3.3 4.0 2.8 3.5 3.4 0.3 5.1 3.9 2.7 4.9 2.2 2.6 4.0 3.2 2.6 2.9 3.6 4.6 3.8 4.9 3.8 3.5 5.1 10.8 3.2 3.9 44.4 7.9 3.3 4.2 2.0 2.8 6.8 5.2 3.7 2.1 8.6 3.2 1.8 4.2 6.4 8.2 6.2 1.9 4.0 2.3 4.8 6.2 5.4 4.8 9.9 34.3 5.1 13.2 6.1 11.2 6.0 22.9 5.8 8.9 10.3 5.8 8.4 37.1 14.7 2.0 7.3 3.1 1.2 7.5 6.1 0.0 50.6 4.9 3.4 6.2 62.4 82.0 3.6 3.4 4.9 15.8 3.3 4.2 1.9 7.3 11.8 0.0 4.0 5.5 7.0 4.5 5.2 4.8 6.2 8.6 2.3 7.6 4.1 SLC11A2 "DCT1, DMT1, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA032139: AB_10964213, HPA032140: AB_10962932" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.07e-6)" "unprognostic (1.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (2.29e-1)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" 12.1 17.0 12.8 14.0 21.6 15.9 30.3 19.6 18.1 29.3 12.7 16.4 53.8 15.7 17.6 23.9 21.4 17.7 14.7 13.2 16.5 22.5 25.6 23.2 10.3 22.8 18.3 12.8 22.6 42.5 10.9 23.7 22.9 24.4 16.2 23.1 31.2 19.3 18.4 20.3 13.8 15.3 19.1 8.7 17.8 13.3 18.5 19.2 41.6 20.3 17.2 20.4 13.9 31.1 19.0 22.4 31.4 28.7 33.5 28.6 106.3 19.7 73.9 19.0 21.8 30.6 35.3 11.8 38.8 22.8 35.7 25.3 26.6 19.2 21.9 17.1 17.4 27.4 29.2 35.5 35.7 19.0 54.5 31.6 24.3 32.7 35.1 45.6 22.8 23.6 24.4 5.6 22.4 21.7 21.8 12.9 46.6 19.8 15.5 14.7 28.6 21.1 23.4 27.7 21.6 19.0 16.3 47.1 20.9 36.2 50.8 12.6 26.8 19.2 15.8 21.5 10.9 14.1 20.4 4.7 54.1 10.2 8.3 0.6 4.7 1.9 4.2 6.8 3.7 2.6 3.3 4.3 7.0 3.3 4.6 4.3 2.3 6.0 4.8 2.9 2.9 3.4 12.8 21.6 19.6 18.1 13.2 16.5 22.8 18.3 22.9 19.1 18.5 31.1 9.8 38.5 46.1 32.7 6.9 15.4 24.8 84.0 22.2 26.6 37.6 18.5 15.5 25.8 69.4 57.0 18.8 27.0 11.9 14.0 3.9 30.6 1.5 31.7 11.6 13.1 16.4 64.8 33.6 28.3 22.5 17.3 15.3 43.6 71.4 20.1 11.4 41.3 35.2 28.6 38.1 14.3 42.7 16.9 25.4 1.7 9.6 30.1 26.6 26.2 15.7 26.5 6.2 51.8 94.5 20.6 15.0 8.6 8.2 47.8 13.2 9.0 109.6 17.8 6.6 14.2 13.2 9.0 12.2 14.3 13.4 19.4 10.7 10.4 15.0 23.1 SLC12A5 "KCC2, KIAA1176" ENSG00000124140 "Solute carrier family 12 member 5" Q9H2X9 20 46021690-46060150 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 145.8;retina: 117.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 244.0;Cone photoreceptor cells: 383.7;Excitatory neurons: 92.7;Inhibitory neurons: 91.3;Rod photoreceptor cells: 170.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 24.9;NB-4: 50.8;SK-BR-3: 24.8;U-2 OS: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072058 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA072058: AB_2686485" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" "unprognostic (9.44e-4)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.48e-1)" "unprognostic (5.16e-3)" "unprognostic (3.61e-1)" "unprognostic (2.49e-1)" "unprognostic (6.63e-2)" "unprognostic (3.72e-3)" "unprognostic (5.61e-4)" "unprognostic (8.78e-4)" "unprognostic (3.25e-2)" "unprognostic (9.22e-2)" "unprognostic (1.99e-1)" "unprognostic (2.34e-2)" 1.5 26.7 101.3 0.9 103.5 0.4 1.0 97.6 145.8 0.9 14.9 1.4 1.0 0.7 0.9 0.4 0.5 0.7 5.1 107.0 96.6 1.1 1.2 2.5 2.2 76.3 80.5 2.3 2.2 1.8 41.5 2.0 69.9 1.0 0.9 117.4 0.7 0.5 0.4 0.6 1.6 0.4 69.3 3.0 1.9 7.8 86.7 2.9 0.7 0.2 1.4 0.6 0.7 88.4 0.0 15.2 6.6 4.9 0.6 0.0 1.5 0.6 0.0 0.0 0.5 2.0 0.0 5.8 22.5 0.4 5.9 1.4 4.3 2.3 0.4 3.7 5.7 4.9 3.0 24.9 2.5 0.0 6.5 0.8 0.0 0.0 0.3 10.0 1.4 5.4 9.3 0.0 0.0 23.1 3.5 50.8 2.4 2.1 7.7 5.8 4.2 1.3 2.3 0.0 8.1 11.5 2.9 24.8 7.9 6.0 9.0 14.4 2.3 2.7 28.0 0.2 1.1 0.0 4.2 8.2 5.9 5.9 0.2 0.0 0.6 0.0 1.1 0.4 0.5 0.4 0.1 0.1 0.1 0.5 2.4 1.3 0.0 0.4 0.1 0.0 1.9 0.3 101.3 103.5 97.6 145.8 107.0 96.6 76.3 80.5 69.9 69.3 86.7 88.4 2.2 0.0 0.0 10.4 0.4 0.5 0.0 0.0 0.0 244.0 0.8 2.2 1.2 0.0 0.0 0.0 383.7 1.6 0.9 0.0 1.9 0.1 1.9 0.4 0.1 2.9 19.9 4.4 92.7 0.2 2.5 0.4 1.5 0.6 0.0 14.4 4.6 1.3 19.8 13.5 91.3 0.7 0.0 2.6 5.3 6.1 0.0 3.4 5.4 10.3 0.6 28.2 0.0 3.5 6.3 0.4 0.0 0.0 0.8 0.2 0.0 0.3 0.0 170.9 0.0 0.0 2.2 4.2 7.7 0.1 0.6 1.6 1.0 8.5 0.3 0.1 SLC12A9 CIP1 ENSG00000146828 "Solute carrier family 12 member 9" Q9BXP2 7 100826820-100867010 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 90.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-BR-3: 61.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067536 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA067536: AB_2732768" "unprognostic (6.53e-2)" "unprognostic (3.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.11e-3)" "unprognostic (3.47e-2)" "unprognostic (2.37e-2)" "unprognostic (8.38e-3)" "prognostic favorable (5.97e-4)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.00e-4)" "unprognostic (2.47e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.52e-2)" "unprognostic (6.00e-2)" "unprognostic (6.74e-3)" "unprognostic (6.38e-2)" 6.9 8.1 7.4 8.7 11.2 7.6 6.3 10.7 10.8 8.3 6.5 8.3 7.8 8.2 1.2 7.3 6.7 9.5 4.2 7.3 8.7 7.4 6.8 8.2 7.3 12.5 10.6 6.7 10.5 6.3 3.6 14.0 11.4 8.0 5.6 0.7 7.4 6.4 2.6 7.9 8.3 6.7 10.1 14.1 7.0 2.7 9.3 5.9 5.8 3.1 3.8 9.2 6.1 13.1 16.1 12.4 4.2 33.9 12.4 7.3 42.2 7.9 15.1 11.7 16.6 17.7 26.7 11.5 25.1 15.0 18.8 17.3 7.3 17.6 3.1 12.3 12.1 4.4 13.8 12.6 15.1 5.4 18.0 18.0 9.9 9.3 9.4 9.5 23.2 9.1 10.5 6.1 16.8 49.8 5.7 25.5 8.3 33.3 24.6 13.3 4.2 17.9 11.6 14.3 7.0 15.8 8.7 61.7 16.7 7.0 7.7 19.1 14.5 14.4 14.3 23.8 14.4 3.2 13.7 4.0 10.2 18.0 17.4 0.0 1.5 0.0 0.2 1.8 0.3 0.6 0.1 0.1 2.4 0.6 0.2 0.1 1.4 0.2 1.9 1.2 0.3 0.9 7.4 11.2 10.7 10.8 7.3 8.7 12.5 10.6 11.4 10.1 9.3 13.1 10.6 3.2 16.1 3.9 12.3 11.0 12.0 6.9 10.8 6.6 12.6 11.0 2.1 11.5 10.1 18.4 2.1 90.0 21.7 14.1 0.0 12.7 0.9 5.6 9.1 13.6 11.4 1.7 2.0 13.4 28.2 10.2 18.3 9.5 1.3 14.7 15.7 6.9 31.2 6.7 2.6 13.6 10.2 23.9 18.3 0.7 9.0 27.2 8.8 3.7 24.6 18.7 8.2 6.0 5.8 14.9 23.7 6.4 9.7 8.3 14.7 10.9 4.8 6.7 13.1 9.4 7.3 1.7 7.8 12.9 11.4 50.2 13.4 17.2 19.6 9.6 SLC13A4 "SUT-1, SUT1" ENSG00000164707 "Solute carrier family 13 member 4" Q9UKG4 7 135681237-135729258 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "choroid plexus: 809.0" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 786.0" "Cancer enhanced" "Detected in single" "testis cancer: 1.3" "Region enhanced" "Detected in many" "hippocampal formation: 45.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048582 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA048582: AB_2680450" "unprognostic (2.40e-1)" "unprognostic (2.51e-1)" "unprognostic (9.70e-3)" "unprognostic (1.78e-1)" "unprognostic (7.69e-2)" "unprognostic (3.96e-6)" "unprognostic (3.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.56e-3)" "unprognostic (9.23e-2)" "unprognostic (2.89e-1)" "unprognostic (1.87e-1)" "unprognostic (2.30e-6)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (2.00e-1)" "unprognostic (6.73e-2)" 0.0 0.0 1.6 0.0 0.7 0.0 0.0 9.2 3.4 0.7 809.0 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.1 45.4 0.7 0.0 0.0 0.0 0.0 0.9 1.7 0.0 0.2 0.0 1.4 54.4 0.6 0.0 0.0 2.3 0.5 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 3.9 12.9 0.0 0.0 0.0 2.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 30.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.1 0.0 2.4 0.1 0.1 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 9.2 3.4 45.4 0.7 0.9 1.7 0.6 0.7 12.9 0.9 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.1 0.0 3.4 0.1 0.1 1.9 0.0 0.1 0.0 4.2 189.9 0.0 0.0 0.0 0.2 0.6 0.5 0.5 1.0 0.0 0.0 2.7 0.0 9.5 1.2 0.0 0.1 0.0 0.1 0.0 0.0 14.9 3.3 3.0 0.0 0.0 0.0 0.3 0.5 0.3 0.4 0.0 1.0 0.0 2.1 0.0 3.5 2.5 0.1 0.0 0.0 0.1 0.5 0.0 0.1 4.3 14.9 0.0 0.6 0.3 0.3 0.5 0.0 0.1 786.0 0.1 0.1 0.0 0.4 SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 414.0" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 381.0" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 79 "Hep G2: 58.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" 0.3 2.7 4.8 0.0 7.0 0.0 0.3 4.8 8.0 0.3 2.7 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.1 5.3 7.9 0.7 414.0 0.0 0.2 6.8 6.1 0.6 0.3 0.0 0.8 0.0 5.4 0.0 0.0 1.7 38.0 0.0 0.0 0.1 0.0 0.0 4.8 3.3 0.0 2.3 8.4 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 58.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 7.0 4.8 8.0 5.3 7.9 6.8 6.1 5.4 4.8 8.4 3.9 0.4 0.0 0.0 24.8 4.8 0.5 0.6 0.6 1.2 0.6 0.1 0.1 0.9 7.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 1.9 0.0 24.0 0.3 0.5 0.1 0.4 0.0 0.1 0.0 0.9 16.8 381.0 0.0 0.0 0.2 0.0 0.0 23.2 1.1 0.4 0.6 0.3 0.0 1.9 0.0 7.0 0.0 1.5 0.1 16.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.6 0.0 0.5 0.5 2.4 2.8 1.2 0.4 0.1 1.0 7.8 0.0 0.3 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 51.0;epididymis: 33.3;retina: 31.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Glandular and luminal cells: 27.4;Kupffer cells: 16.7;Macrophages: 21.8;Rod photoreceptor cells: 45.1" "Group enriched" "Detected in many" 6 "breast cancer: 10.9;melanoma: 11.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 13 "SK-MEL-30: 481.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054459: AB_2682494, HPA066328: AB_2685660" "unprognostic (2.53e-2)" "unprognostic (2.09e-3)" "unprognostic (8.41e-2)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.26e-3)" "unprognostic (5.08e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-2)" "unprognostic (8.78e-2)" "unprognostic (2.23e-1)" "unprognostic (8.16e-3)" "unprognostic (2.09e-2)" "unprognostic (9.46e-2)" 1.5 2.7 3.0 7.2 4.8 9.7 5.8 4.3 4.3 1.6 51.0 0.7 0.5 2.6 33.3 10.9 0.9 1.3 0.9 5.0 5.2 0.7 1.4 3.0 5.3 5.1 4.2 1.5 0.5 0.1 1.7 2.3 5.3 0.6 0.8 31.0 2.2 4.2 5.0 4.5 1.2 0.8 2.4 5.7 1.0 2.3 5.2 1.6 3.5 0.7 4.7 2.1 2.6 3.2 2.1 1.8 0.6 0.8 0.4 0.6 14.2 0.8 18.0 1.7 1.2 0.7 2.5 17.6 1.4 0.0 0.2 0.6 2.5 0.0 0.7 5.4 1.3 1.4 2.2 22.3 3.2 5.7 1.1 0.8 0.2 1.0 1.0 1.7 0.8 2.5 1.1 3.8 0.0 18.1 8.5 3.6 0.2 0.1 1.0 0.1 0.4 2.4 0.8 1.5 4.2 0.3 0.8 10.7 481.5 3.8 15.0 3.5 2.7 5.9 1.1 0.5 2.0 4.2 17.5 14.6 36.0 4.6 2.6 0.8 3.1 0.2 1.8 2.7 0.8 0.4 0.6 1.4 1.9 0.0 0.4 0.8 5.4 0.4 1.4 0.3 1.5 0.9 3.0 4.8 4.3 4.3 5.0 5.2 5.1 4.2 5.3 2.4 5.2 3.2 0.6 0.0 2.5 1.6 1.8 0.3 0.2 0.1 1.2 8.2 2.5 0.9 0.8 0.0 4.0 9.2 22.9 0.4 8.4 0.0 0.0 0.0 0.7 4.7 2.5 3.2 0.0 2.7 6.7 0.0 11.5 0.9 0.5 27.4 1.3 0.1 0.7 0.3 5.6 0.0 6.2 0.0 0.0 16.7 7.0 0.3 0.0 21.8 10.6 4.7 11.1 6.2 5.2 0.5 0.8 0.0 0.0 1.9 5.0 0.2 0.0 0.3 1.6 45.1 0.0 0.8 0.3 1.7 0.7 6.7 0.4 0.4 5.3 0.4 0.1 0.2 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC17A3 NPT4 ENSG00000124564 "Solute carrier family 17 member 3" O00476 6 25833066-25882286 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 164.3" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 197.8" "Cancer enriched" "Detected in some" 17 "renal cancer: 57.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 210 "RPTEC TERT1: 114.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.31e-3)" "unprognostic (1.56e-2)" "unprognostic (2.51e-1)" "unprognostic (4.65e-2)" "unprognostic (5.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (2.34e-1)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.3 37.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 1.8 0.0 0.0 0.2 0.1 7.9 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 15.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 197.8 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.1 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 SLC20A1 "Glvr-1, GLVR1, PiT-1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 353.3;Paneth cells: 261.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 522.4;U-87 MG: 507.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834" Approved Approved "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB019279: , HPA035834: AB_2674809" "unprognostic (1.81e-1)" "unprognostic (2.18e-1)" "unprognostic (5.38e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.50e-2)" "unprognostic (3.38e-2)" "unprognostic (2.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.43e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.44e-5)" "unprognostic (6.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-3)" 36.1 11.7 16.2 33.2 24.3 74.6 15.6 27.8 26.3 11.8 25.0 53.6 14.4 13.7 8.4 15.0 14.5 26.4 21.8 20.7 19.8 22.1 49.0 29.2 37.1 25.5 20.7 9.2 30.7 10.4 15.9 29.7 25.2 13.3 21.9 52.3 12.8 9.3 19.7 14.5 28.4 15.0 18.6 29.5 20.2 15.7 24.5 27.2 15.9 7.5 27.5 40.8 13.3 21.2 69.0 55.5 71.1 57.8 52.9 128.8 54.4 181.6 215.3 79.1 102.2 85.0 164.9 124.0 97.5 67.7 305.0 70.5 78.8 138.0 114.8 68.5 80.4 105.5 57.1 81.3 78.2 61.2 178.9 66.0 53.8 279.1 193.9 522.4 102.2 52.9 199.5 126.3 346.7 26.8 83.9 235.9 119.3 31.8 147.6 77.8 63.5 34.9 114.5 312.8 64.4 60.8 91.7 54.9 127.9 31.4 56.0 42.9 223.6 143.5 94.7 50.8 142.4 52.1 143.7 102.2 507.2 57.9 178.3 13.4 33.5 30.1 52.8 59.8 59.4 8.3 22.2 38.4 25.4 5.0 17.5 27.6 14.7 50.2 37.2 41.8 14.6 33.9 16.2 24.3 27.8 26.3 20.7 19.8 25.5 20.7 25.2 18.6 24.5 21.2 61.7 12.8 25.9 42.4 40.3 112.8 59.1 38.7 104.7 60.0 41.9 31.6 49.6 32.9 35.3 9.2 210.6 44.7 119.1 353.3 13.7 18.1 1.5 86.0 34.3 48.2 35.7 53.2 47.3 14.0 13.5 61.5 96.4 167.8 25.3 20.6 41.0 58.1 28.2 20.2 27.2 85.8 32.6 58.5 86.2 3.3 3.7 80.5 26.6 19.7 42.8 31.8 66.9 18.6 26.1 26.9 261.6 4.9 59.8 34.0 156.3 5.2 59.6 84.6 0.0 36.9 25.9 8.5 18.7 119.5 61.8 74.3 70.4 19.0 96.5 90.3 SLC20A2 "Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1" ENSG00000168575 "Solute carrier family 20 member 2" Q08357 8 42416475-42541926 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Phosphate transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 130.6;skeletal muscle: 131.2" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 250.2;Oligodendrocytes: 151.7;Urothelial cells: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 132.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026540 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA026540: AB_1855408" "prognostic unfavorable (7.67e-4)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.27e-2)" "unprognostic (2.12e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.95e-1)" "unprognostic (7.62e-2)" "unprognostic (2.06e-1)" "unprognostic (3.43e-2)" "prognostic favorable (1.01e-4)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (5.86e-2)" "unprognostic (4.95e-2)" 11.9 8.0 33.4 9.8 45.3 3.0 12.1 55.4 37.1 15.8 130.6 22.8 46.7 18.5 9.9 32.7 24.5 15.1 63.2 30.1 48.7 17.5 39.7 15.1 6.5 46.5 56.5 8.1 51.6 15.0 10.5 13.5 47.5 13.6 19.0 7.5 87.9 17.6 131.2 23.3 18.8 17.9 42.7 7.4 15.1 15.9 67.8 11.9 82.8 57.6 9.1 22.0 21.7 52.8 52.7 14.3 19.0 16.0 10.4 8.8 41.1 46.9 80.8 23.9 58.7 38.9 132.9 17.4 53.6 42.1 13.5 81.1 11.4 45.2 41.6 4.3 8.7 27.8 4.8 22.0 14.9 9.9 12.3 9.5 40.2 24.7 22.7 16.7 12.0 13.7 27.2 14.0 47.3 14.4 18.1 16.1 19.2 50.5 8.8 14.9 20.9 18.5 21.4 47.5 5.1 19.2 12.8 21.8 12.8 15.0 17.5 17.3 34.9 50.0 17.4 12.3 25.7 9.0 22.2 12.6 15.8 19.5 28.3 3.2 2.2 0.2 3.6 1.6 4.3 2.1 4.0 3.5 3.7 2.1 4.8 3.7 0.8 6.8 1.3 2.0 4.1 3.1 33.4 45.3 55.4 37.1 30.1 48.7 46.5 56.5 47.5 42.7 67.8 52.8 11.1 28.9 18.6 51.6 9.1 98.9 250.2 22.7 96.2 13.4 21.7 14.9 60.2 14.3 21.7 16.5 16.7 23.9 14.3 76.2 13.7 29.6 10.4 79.9 15.8 18.9 12.0 6.9 88.9 31.4 23.7 15.8 15.8 61.2 3.8 17.1 6.4 30.7 10.2 6.7 88.4 11.5 18.3 7.7 12.2 10.0 7.2 10.2 10.6 78.7 7.3 14.4 14.4 63.3 151.7 47.4 35.8 11.7 8.6 76.6 20.0 7.3 57.6 10.2 6.6 22.9 28.3 5.2 7.2 73.9 74.3 25.4 14.2 23.7 12.5 170.3 SLC22A13 "OAT10, OCTL1, OCTL3, ORCTL3" ENSG00000172940 "Solute carrier family 22 member 13" Q9Y226 3 38265812-38278757 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "kidney: 9.0" "Group enriched" "Detected in some" 12 "Excitatory neurons: 2.3;Inhibitory neurons: 1.8;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in single" 7 "renal cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035603, HPA035962" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035603: AB_10672869, HPA035962: AB_2674890" "unprognostic (2.73e-2)" "unprognostic (6.70e-2)" "unprognostic (2.80e-1)" "unprognostic (5.68e-2)" "unprognostic (7.13e-3)" "unprognostic (3.50e-3)" "unprognostic (6.83e-2)" "unprognostic (1.49e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-5)" "unprognostic (3.39e-1)" "unprognostic (1.96e-2)" "unprognostic (5.24e-2)" "unprognostic (2.74e-1)" 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC22A14 "OCTL2, ORCTL4" ENSG00000144671 "Solute carrier family 22 member 14" Q9Y267 3 38282294-38318575 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 11.6" "Group enriched" "Detected in some" 7 "Early spermatids: 70.1;Late spermatids: 101.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.26e-2)" "unprognostic (6.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (6.25e-2)" "unprognostic (4.78e-2)" "unprognostic (2.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.07e-1)" "unprognostic (4.97e-2)" "unprognostic (4.81e-2)" "unprognostic (1.69e-1)" "unprognostic (3.57e-4)" "unprognostic (2.19e-1)" "unprognostic (4.02e-2)" "unprognostic (1.69e-1)" "unprognostic (2.35e-1)" 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.7 2.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.6 0.0 0.6 0.2 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 11.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.6 0.7 2.1 0.6 0.0 0.5 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.1 0.0 1.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 70.1 0.5 0.2 0.1 0.0 0.0 11.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.1 1.7 8.3 0.0 0.0 0.0 0.0 101.8 0.9 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.1 0.0 0.1 0.2 1.4 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC23A1 "SLC23A2, SVCT1, YSPL3" ENSG00000170482 "Solute carrier family 23 member 1" Q9UHI7 5 139367196-139384553 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "fallopian tube: 54.2;intestine: 65.3;kidney: 40.2;liver: 22.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 65.2;Hepatocytes: 19.3;Proximal enterocytes: 131.7;Proximal tubular cells: 27.0" "Group enriched" "Detected in many" 5 "endometrial cancer: 2.1;liver cancer: 7.7;prostate cancer: 4.0;renal cancer: 3.9" "Region enhanced" "Detected in some" "midbrain: 3.2" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 9.4;HDLM-2: 8.3;Hep G2: 13.6;JURKAT: 15.5;Karpas-707: 10.9;RPMI-8226: 10.9;U-266/70: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047612 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA047612: AB_2680102" "unprognostic (4.00e-3)" "unprognostic (2.66e-3)" "unprognostic (2.63e-2)" "unprognostic (1.75e-3)" "unprognostic (1.93e-1)" "unprognostic (6.36e-6)" "unprognostic (7.41e-2)" "unprognostic (6.55e-2)" "unprognostic (5.88e-2)" "unprognostic (3.90e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (4.16e-2)" "unprognostic (1.55e-2)" "unprognostic (3.65e-3)" 0.2 0.1 0.1 1.2 0.2 2.8 0.2 1.1 0.2 2.3 0.1 3.3 26.3 0.7 0.0 0.3 54.2 2.4 0.1 0.2 0.4 40.2 22.5 0.9 1.7 1.1 3.2 0.3 1.2 0.3 0.2 0.1 0.8 6.3 1.5 0.6 3.2 0.6 0.4 1.9 65.3 0.2 0.1 1.3 1.5 0.2 0.2 5.5 0.2 0.0 1.2 0.4 0.3 0.6 0.3 2.1 0.4 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.4 1.3 5.8 3.0 0.0 0.1 0.3 0.0 0.0 0.1 8.3 0.1 0.2 0.8 13.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 15.5 0.1 10.9 0.0 0.2 5.7 1.0 0.1 0.8 0.1 6.8 0.3 10.9 0.5 0.4 0.3 0.3 0.3 1.9 0.0 0.7 5.0 0.1 0.3 0.3 0.3 0.1 0.0 16.6 2.2 7.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.1 0.2 1.1 0.2 0.2 0.4 1.1 3.2 0.8 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.3 1.5 2.0 0.0 4.2 0.4 0.4 1.9 5.9 0.2 0.0 65.2 0.7 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 1.5 0.0 0.1 0.4 19.3 0.1 0.0 1.2 3.6 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.1 3.1 0.0 0.4 0.9 131.7 27.0 13.4 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 4.2 0.2 SLC25A15 "D13S327, HHH, ORC1, ORNT1" ENSG00000102743 "Solute carrier family 25 member 15" Q9Y619 13 40789412-40812460 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 37.6;liver: 88.3;pancreas: 52.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.5;Hepatocytes: 39.8;Proximal enterocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042146 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042146: AB_2677874" "unprognostic (4.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.85e-1)" "prognostic favorable (2.16e-4)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "prognostic favorable (1.74e-4)" "unprognostic (4.04e-3)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (5.46e-4)" 2.3 1.4 2.0 4.1 2.2 5.6 4.6 2.3 2.5 2.1 2.3 5.9 37.6 3.1 1.1 3.2 2.6 5.0 2.8 1.9 2.6 5.6 88.3 2.3 4.8 2.6 2.3 2.9 52.1 3.4 1.3 2.8 2.5 2.8 6.5 2.8 3.4 1.8 5.9 3.7 26.7 3.4 2.1 2.5 5.5 9.4 2.4 5.3 17.3 6.0 5.3 2.6 1.6 2.9 7.4 14.7 16.5 21.3 6.5 8.2 17.3 5.6 2.9 6.8 3.9 17.6 15.2 48.0 6.4 10.3 12.7 12.6 26.6 15.5 7.0 11.9 12.4 37.0 8.6 26.6 12.7 15.0 5.3 9.0 8.6 9.6 21.9 4.6 11.2 23.8 18.1 7.8 11.8 28.2 10.2 9.9 33.2 32.7 7.9 25.5 12.0 10.6 11.7 7.0 7.7 20.1 10.2 18.4 10.1 11.5 13.6 23.2 8.4 8.4 12.1 12.7 17.0 8.9 9.6 27.9 8.4 11.4 16.4 1.3 0.5 0.1 1.6 0.9 1.0 0.6 1.0 1.1 1.1 0.7 1.0 2.0 0.7 1.4 0.5 0.5 0.9 0.5 2.0 2.2 2.3 2.5 1.9 2.6 2.6 2.3 2.5 2.1 2.4 2.9 0.3 3.2 0.5 3.9 1.3 0.3 1.0 0.8 2.2 1.4 2.1 1.4 1.1 1.5 0.2 0.0 0.0 2.2 1.3 0.6 7.9 2.1 4.6 1.2 2.1 0.9 1.2 9.0 2.4 4.3 44.5 1.0 1.5 2.1 0.0 1.5 0.7 39.8 1.7 0.0 4.3 0.6 2.0 1.6 0.3 6.8 0.6 1.0 1.8 1.0 0.0 0.4 2.1 5.0 1.4 1.7 2.7 0.0 6.2 1.6 19.0 4.3 0.1 1.9 0.0 1.0 1.1 5.4 9.3 2.1 0.1 1.5 3.2 4.3 3.5 0.8 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 82.2;Langerhans cells: 160.3;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA021936: " "unprognostic (2.28e-1)" "unprognostic (7.05e-3)" "unprognostic (8.21e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.21e-7)" "unprognostic (6.71e-2)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.77e-3)" "unprognostic (2.71e-3)" "unprognostic (3.58e-2)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" 10.9 31.2 11.6 16.0 12.4 8.0 6.4 13.1 13.3 7.3 12.4 9.8 9.4 6.7 2.4 8.6 6.3 6.2 10.6 11.7 12.6 10.9 8.8 11.7 22.9 14.9 12.6 6.2 8.8 8.1 4.8 12.1 13.2 6.1 8.8 3.1 6.2 3.7 14.5 4.9 8.5 7.1 13.0 14.6 10.9 33.0 14.7 8.6 6.0 16.7 18.8 11.5 5.7 14.7 28.3 34.8 6.2 18.4 13.6 7.0 20.0 18.1 7.0 20.3 20.5 59.8 17.4 89.8 12.8 6.4 17.7 24.7 43.5 20.9 25.3 26.5 70.5 41.1 40.4 58.4 11.5 58.7 44.9 6.1 11.6 31.5 25.2 4.7 33.9 44.9 51.0 41.9 6.5 59.3 61.8 59.3 13.5 55.3 67.8 47.4 19.8 85.1 14.1 19.7 60.7 15.3 19.3 51.4 22.2 10.2 32.1 47.3 12.0 12.1 24.1 23.5 49.0 102.7 53.4 95.8 9.5 66.9 15.5 0.3 21.0 2.3 16.2 25.2 16.6 36.3 12.7 15.4 24.9 29.7 14.2 14.7 1.7 10.0 14.8 31.0 17.7 14.5 11.6 12.4 13.1 13.3 11.7 12.6 14.9 12.6 13.2 13.0 14.7 14.7 5.1 6.4 6.7 3.3 27.6 15.2 10.8 6.0 2.8 1.2 5.4 7.5 0.6 2.8 6.1 7.3 2.1 7.5 13.3 8.6 23.5 6.5 18.0 5.6 8.7 6.7 3.0 11.1 3.1 5.3 82.2 8.6 9.7 3.5 11.4 2.7 2.5 2.9 44.1 3.3 3.5 6.2 4.1 9.5 160.3 24.1 3.1 31.5 24.9 4.7 38.8 1.6 11.3 2.0 2.4 5.1 8.6 3.4 26.5 14.1 6.5 6.4 3.9 6.0 6.6 5.9 10.0 79.6 11.9 7.9 12.9 8.9 12.5 11.4 11.0 9.7 SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 238.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.2;Proximal enterocytes: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" 28.8 38.0 144.8 12.0 238.7 0.8 18.0 77.5 200.1 32.1 72.0 94.4 39.3 41.8 24.0 64.7 36.6 21.4 79.0 206.5 95.1 45.0 38.5 24.0 9.2 108.8 98.2 33.6 24.2 58.8 22.2 4.7 109.5 35.0 49.1 41.2 68.9 40.0 90.8 33.5 40.5 65.5 82.7 11.9 41.3 9.5 101.4 7.2 60.7 78.2 31.2 55.8 31.1 115.8 58.2 22.9 32.2 101.9 42.3 18.6 14.9 17.0 26.4 31.0 37.2 58.2 37.1 32.2 40.0 41.3 34.1 48.0 66.3 39.0 24.3 0.1 58.6 23.2 46.7 46.2 39.2 1.6 52.5 53.3 33.4 27.6 12.0 62.9 32.8 34.7 68.8 39.4 6.2 41.6 20.7 32.8 23.6 61.0 71.1 10.0 8.8 49.4 83.3 10.2 2.4 31.9 11.7 70.8 30.0 34.8 37.1 50.1 11.7 9.8 41.8 2.6 11.2 7.3 10.7 28.3 4.5 54.2 15.6 0.5 0.0 0.0 2.0 0.0 0.4 1.0 1.1 0.9 0.2 0.4 1.5 1.4 0.0 0.3 0.0 0.4 1.3 0.4 144.8 238.7 77.5 200.1 206.5 95.1 108.8 98.2 109.5 82.7 101.4 115.8 6.2 9.6 20.9 11.8 7.0 10.5 8.8 11.5 12.0 13.1 18.9 15.6 39.5 47.1 10.0 46.0 8.4 1.4 4.5 164.2 19.6 54.7 15.9 8.2 6.4 8.0 13.8 1.3 24.7 28.5 1.8 10.2 12.8 17.5 7.0 17.9 16.1 38.0 2.7 8.4 17.9 34.5 10.2 3.0 2.6 71.2 19.0 1.4 17.8 12.2 1.0 28.7 4.1 17.1 12.6 55.5 57.9 29.3 17.6 13.6 106.8 28.7 6.4 22.0 13.1 12.1 12.7 0.5 4.6 34.1 23.3 0.8 5.2 39.5 34.2 30.3 SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1537.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1748.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 83000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045709: AB_10965843" "unprognostic (1.16e-2)" "unprognostic (4.68e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-2)" "unprognostic (6.38e-2)" "unprognostic (3.25e-3)" "unprognostic (9.41e-2)" "unprognostic (4.98e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "prognostic favorable (8.11e-7)" "unprognostic (3.45e-1)" "unprognostic (2.99e-1)" "unprognostic (8.66e-3)" "unprognostic (4.72e-2)" 300.9 550.7 131.2 184.7 136.0 209.2 267.5 159.3 146.5 224.3 209.3 418.9 396.4 283.5 226.1 437.7 248.9 136.2 1237.8 132.6 160.4 419.8 370.1 255.7 201.7 148.9 149.6 290.2 392.2 499.7 216.9 192.4 153.0 209.9 347.6 167.2 302.7 220.9 1537.4 275.7 321.2 257.4 150.4 235.1 423.5 90.8 159.0 205.7 225.1 1233.2 312.8 294.7 264.6 135.4 731.4 447.1 620.0 509.6 534.1 891.5 1005.3 622.8 724.1 704.3 573.4 787.6 316.4 1003.2 376.9 633.0 320.3 573.7 616.9 741.3 680.6 402.9 651.8 589.5 297.4 563.3 683.0 665.7 416.6 857.3 616.8 494.2 681.2 994.3 990.8 488.8 654.9 240.5 782.7 436.5 642.5 724.2 605.4 540.6 988.5 703.0 730.3 1075.0 858.8 559.6 355.5 506.1 740.1 565.5 1009.8 504.4 771.0 676.3 782.0 371.2 390.0 442.8 603.4 486.5 648.5 678.1 295.6 368.3 494.9 184.7 408.9 223.2 244.7 520.2 285.6 298.5 270.8 271.4 534.7 222.6 281.3 269.8 166.6 288.5 545.2 321.7 377.4 637.0 131.2 136.0 159.3 146.5 132.6 160.4 148.9 149.6 153.0 150.4 159.0 135.4 319.2 214.7 294.8 46.0 392.2 376.0 590.6 751.4 495.1 223.1 442.5 549.3 1748.6 370.3 384.5 215.2 79.2 785.9 480.8 727.5 874.6 512.1 41.7 217.9 275.3 328.6 312.4 413.5 44.9 879.5 946.2 393.1 390.4 288.7 210.4 477.9 278.1 416.3 589.4 292.7 49.7 470.7 370.2 467.9 280.7 29.0 255.1 449.1 437.6 34.7 593.5 317.3 294.5 32.2 42.2 632.9 602.7 256.5 442.7 652.4 945.5 1029.4 201.1 230.2 302.4 470.5 733.5 126.1 169.9 796.6 362.4 814.7 356.3 536.0 729.1 769.9 SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 272 "testis: 47.3" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 198.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Enhanced Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA015064: AB_1847691, HPA016841: AB_1847690, HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.70e-1)" "unprognostic (5.32e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.5 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.2 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.9;Syncytiotrophoblasts: 17.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" 5.7 8.3 2.9 4.9 3.9 6.1 8.6 3.5 4.4 10.0 4.6 7.7 6.1 13.4 7.6 5.4 7.1 5.2 4.8 2.9 3.2 15.0 4.6 6.8 5.0 3.9 4.0 2.9 12.2 6.1 12.8 4.1 4.1 8.7 5.3 4.5 6.4 5.2 2.2 4.5 7.7 4.1 3.3 8.9 12.5 24.5 4.4 5.2 9.1 1.5 3.5 6.0 5.0 4.2 5.0 13.5 2.4 10.0 7.5 2.9 5.5 3.2 2.8 3.4 3.7 1.6 12.4 5.8 3.3 3.7 7.1 11.0 2.8 3.8 1.9 3.2 3.6 4.8 11.1 1.9 2.7 0.7 12.8 5.9 2.1 6.5 1.2 2.5 5.4 6.8 1.4 2.0 2.9 2.7 5.3 2.7 0.8 3.4 4.4 5.8 1.6 2.6 2.6 12.6 1.2 3.0 9.2 5.4 4.1 2.4 12.2 3.6 7.6 2.3 1.7 5.6 2.7 4.3 2.9 2.1 5.9 8.6 6.1 4.1 5.6 7.6 4.0 8.8 3.3 1.9 3.7 4.3 5.7 3.6 1.3 2.5 1.1 2.8 6.5 3.0 4.1 2.5 2.9 3.9 3.5 4.4 2.9 3.2 3.9 4.0 4.1 3.3 4.4 4.2 3.1 0.0 5.4 5.2 3.6 0.8 1.5 1.4 2.8 4.3 6.3 4.1 1.0 5.7 1.8 11.0 8.4 9.2 2.1 3.8 11.7 2.8 3.8 10.2 1.9 2.8 9.0 4.6 0.5 7.1 2.3 3.0 5.1 10.6 5.1 1.3 1.8 2.8 6.7 1.7 0.7 3.0 2.0 6.4 1.5 5.5 1.5 4.2 0.0 4.7 5.8 7.9 3.1 1.0 2.5 3.2 6.0 1.2 3.7 1.9 2.4 7.3 2.0 9.0 0.0 1.1 1.2 20.9 0.8 1.9 0.3 17.4 3.2 9.1 3.1 1.9 SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: AB_1857048" "unprognostic (4.12e-2)" "unprognostic (9.98e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (6.52e-2)" "unprognostic (3.46e-1)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "unprognostic (1.99e-2)" "unprognostic (2.47e-2)" "unprognostic (3.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (6.03e-2)" "prognostic favorable (1.55e-4)" 27.1 22.2 16.6 14.3 16.2 61.6 33.5 16.2 22.7 31.9 13.9 25.7 30.9 34.4 47.7 15.0 32.6 18.4 39.8 16.1 20.1 38.7 4.2 27.5 21.3 17.0 16.4 39.0 45.2 28.9 26.9 26.4 17.5 27.1 19.5 42.6 23.4 20.8 38.4 22.5 22.9 19.2 16.9 20.1 34.0 23.8 18.2 20.6 31.8 20.8 17.6 23.0 23.9 21.5 52.3 11.5 36.0 30.8 33.0 40.7 46.2 19.4 23.6 18.2 27.3 28.6 24.0 42.1 46.9 17.3 31.2 34.9 40.1 15.2 40.6 33.8 36.5 33.9 29.8 20.9 45.9 48.8 21.3 44.1 61.1 15.4 45.8 44.4 22.0 32.0 17.6 27.4 29.2 22.8 30.6 34.1 37.8 12.8 18.4 34.2 32.0 59.6 23.5 17.7 22.4 38.2 26.7 45.1 80.9 30.3 32.6 29.2 24.1 29.5 17.1 52.2 19.0 56.4 36.8 51.2 36.0 21.1 15.0 10.7 9.2 15.1 9.6 11.5 11.8 16.3 9.6 10.2 14.0 15.1 13.5 12.6 1.7 18.3 13.5 9.7 9.9 9.8 16.6 16.2 16.2 22.7 16.1 20.1 17.0 16.4 17.5 16.9 18.2 21.5 60.3 99.3 143.0 85.5 47.6 68.2 68.0 38.1 116.7 106.0 72.2 77.5 90.3 38.6 52.0 71.7 133.5 58.8 58.2 22.7 64.6 26.4 10.6 113.4 78.0 45.8 59.3 27.3 127.7 38.3 38.0 73.9 58.1 106.3 65.9 92.8 35.7 0.5 26.5 92.5 115.6 32.5 30.5 38.2 45.8 16.0 59.7 38.4 56.9 46.9 36.9 68.2 25.7 108.6 109.1 29.3 22.8 59.5 48.2 88.9 44.9 57.5 98.8 121.8 59.2 80.0 59.2 59.4 68.8 61.3 54.4 49.4 49.1 83.2 46.8 78.9 SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" 19.1 35.4 22.2 18.8 23.3 70.0 21.0 25.9 26.8 23.8 33.6 28.1 25.3 27.3 27.6 14.5 27.3 19.4 20.7 22.9 26.3 28.7 58.0 21.0 36.2 24.2 24.1 44.1 45.6 38.7 30.7 15.4 25.3 29.2 36.9 23.0 22.5 23.9 48.2 16.7 25.2 20.3 22.6 27.2 33.8 18.7 26.0 33.6 52.0 35.7 35.4 27.8 19.1 23.3 24.3 38.3 24.3 41.2 56.4 46.4 30.8 33.6 46.1 48.3 43.7 26.3 5.6 67.8 19.6 31.6 40.7 18.4 55.2 40.1 36.0 43.6 45.0 52.0 33.5 40.2 75.6 37.7 33.9 58.8 46.1 46.2 93.2 44.6 31.5 52.8 47.7 40.6 36.4 35.2 44.7 67.0 66.2 35.9 44.3 16.2 26.4 47.7 37.5 45.4 24.3 31.1 11.9 65.9 34.0 44.5 33.5 35.0 26.9 38.3 26.4 56.2 48.9 54.7 93.1 41.9 29.3 48.3 24.7 30.7 9.6 18.1 38.8 5.7 44.7 50.8 39.1 43.3 14.9 37.8 41.7 40.5 1.0 57.0 8.4 18.5 55.3 29.2 22.2 23.3 25.9 26.8 22.9 26.3 24.2 24.1 25.3 22.6 26.0 23.3 10.4 22.4 27.4 8.5 35.6 11.5 13.0 12.5 28.5 13.2 26.1 22.6 16.8 22.8 9.6 27.6 6.2 35.2 33.1 21.9 21.5 15.7 6.5 26.6 16.3 11.1 12.6 73.7 8.9 16.9 32.6 13.7 16.8 38.5 22.2 24.0 9.7 27.0 15.2 5.0 10.1 25.6 12.2 7.0 13.7 12.9 15.5 9.8 12.4 1.9 11.2 18.9 29.9 7.1 6.2 13.4 22.2 13.5 23.3 17.7 23.1 31.3 12.3 12.6 6.6 15.2 14.9 11.0 7.8 19.4 10.2 19.4 36.6 32.8 26.7 8.4 SLC25A39 "CGI-69, FLJ22407" ENSG00000013306 "Solute carrier family 25 member 39" Q9BZJ4 17 44319625-44324870 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Heme biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 491.0;Erythroid cells: 1310.3;Late spermatids: 756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026785 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" "HPA026785: AB_10601715" "unprognostic (8.10e-2)" "unprognostic (2.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.29e-1)" "unprognostic (6.04e-2)" "unprognostic (2.35e-3)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "prognostic favorable (3.58e-5)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.22e-1)" "unprognostic (3.21e-2)" 52.4 123.2 71.4 49.3 72.6 305.6 49.6 72.1 84.4 53.3 84.4 77.5 73.9 47.3 39.8 143.4 44.6 41.7 68.4 67.8 72.4 178.0 142.8 56.1 48.7 75.3 72.7 44.9 120.8 98.9 73.4 46.3 74.9 75.3 47.3 9.4 77.7 43.9 44.7 87.1 62.7 30.4 72.4 89.2 81.8 89.4 76.2 35.6 87.1 47.9 40.2 55.9 62.2 71.4 247.0 152.9 47.0 198.0 89.3 68.8 163.0 79.9 71.8 101.8 78.3 151.9 116.0 131.0 137.7 114.0 180.6 124.0 147.2 242.6 35.9 154.9 236.2 68.9 131.2 281.2 97.1 120.9 145.0 104.8 211.9 95.5 122.2 92.2 105.2 195.3 205.7 204.0 87.4 463.5 153.3 118.0 92.5 187.3 417.4 182.6 129.1 375.6 177.9 128.8 316.1 118.2 92.5 146.5 166.8 85.9 281.3 102.4 76.2 132.9 185.9 229.6 160.3 126.9 165.1 122.6 119.7 93.8 82.4 36.5 56.2 29.2 73.7 83.5 83.0 96.1 79.1 79.0 89.5 78.0 80.3 74.1 8.2 139.6 87.7 103.5 80.3 93.2 71.4 72.6 72.1 84.4 67.8 72.4 75.3 72.7 74.9 72.4 76.2 71.4 36.1 9.6 25.4 17.6 52.2 53.3 71.2 117.2 42.1 18.8 93.2 77.0 27.0 52.9 79.9 69.9 10.4 93.1 42.3 123.7 491.0 188.1 223.6 28.6 24.7 44.5 65.3 1310.3 20.7 310.6 166.3 35.2 71.9 54.1 32.9 44.4 30.0 75.7 134.7 13.5 19.5 120.9 132.2 62.5 44.7 756.5 39.7 61.6 92.5 10.3 99.9 45.3 62.8 8.0 16.0 176.7 88.9 38.7 80.0 162.4 130.9 322.8 41.3 15.3 19.7 27.9 52.3 134.4 105.5 110.7 64.6 117.5 51.8 75.4 157.7 108.2 SLC25A44 "FLJ90431, KIAA0446" ENSG00000160785 "Solute carrier family 25 member 44" Q96H78 1 156193932-156212796 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 114.1;Late spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 70.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065411 Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA065411: AB_2685486" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-1)" "unprognostic (2.44e-3)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.72e-2)" "unprognostic (8.92e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "prognostic favorable (2.49e-4)" "unprognostic (3.37e-2)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (8.13e-2)" "unprognostic (2.37e-1)" 18.3 11.6 17.5 10.4 18.7 12.8 9.5 14.4 23.1 8.8 8.5 11.2 18.2 9.5 11.2 11.9 9.2 11.2 14.1 19.5 17.2 27.7 35.3 11.4 10.4 15.8 16.9 6.8 8.8 17.2 13.4 8.3 17.4 9.4 11.5 18.2 8.7 9.3 17.6 11.1 13.0 11.5 13.6 16.6 11.4 12.4 18.0 14.6 10.4 21.2 12.4 14.8 8.4 18.3 18.3 30.5 14.6 19.5 31.0 16.7 11.6 19.2 27.9 33.8 27.5 30.1 16.4 14.4 16.3 28.6 18.3 26.6 53.9 22.5 29.8 16.6 18.0 13.1 18.8 18.4 23.8 17.2 23.2 23.6 19.3 34.3 20.6 16.3 27.8 17.5 14.0 23.0 23.6 32.7 18.1 12.2 34.6 34.6 31.2 11.5 14.8 24.6 44.2 21.2 22.8 30.7 22.3 40.0 26.1 25.6 30.1 27.8 22.7 19.6 16.4 22.0 23.1 23.4 19.2 21.5 21.6 17.8 19.8 14.2 18.2 19.3 9.3 19.1 9.6 8.2 7.4 8.9 13.4 5.4 6.0 7.3 70.5 9.4 16.1 5.8 7.3 13.5 17.5 18.7 14.4 23.1 19.5 17.2 15.8 16.9 17.4 13.6 18.0 18.3 16.4 12.8 22.4 7.5 11.1 27.8 6.2 5.5 10.8 14.4 33.0 25.4 41.1 11.5 11.5 9.2 20.9 5.2 12.0 10.4 5.9 6.0 114.1 17.9 12.3 16.6 6.0 9.5 12.0 5.6 4.0 15.6 12.2 35.4 5.1 5.3 11.7 34.0 7.5 20.2 12.4 11.7 8.2 11.3 34.4 95.6 7.2 19.1 12.4 6.5 10.1 8.2 22.6 5.5 11.6 6.2 6.1 5.7 10.2 6.6 13.8 17.1 5.2 9.0 19.7 40.7 10.8 9.6 10.3 17.6 34.1 8.2 12.8 7.3 8.5 6.9 SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 238.9;Late spermatids: 448.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA039601: AB_2676592, HPA071582: AB_2686422" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "prognostic favorable (8.41e-4)" "unprognostic (4.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.98e-1)" 22.9 15.9 10.4 19.9 11.8 17.6 16.4 12.7 16.7 18.5 7.8 22.1 23.8 14.7 10.5 21.2 10.7 15.8 31.1 12.2 12.2 29.7 30.0 16.7 22.5 12.4 10.2 11.7 15.4 20.6 4.9 17.0 13.2 15.7 21.6 18.8 13.3 16.0 55.8 14.9 20.9 20.8 10.3 15.7 20.1 21.9 11.2 24.8 19.8 60.2 26.8 19.0 6.6 14.1 36.2 27.7 25.7 20.7 65.2 60.2 9.9 44.3 55.9 47.5 59.3 37.6 28.7 96.8 44.8 50.1 61.9 29.6 41.0 71.2 54.3 61.8 20.8 40.1 35.2 25.6 53.1 37.3 40.2 49.9 25.4 55.5 39.6 29.5 31.9 37.2 31.4 56.4 54.1 27.3 54.0 17.2 18.1 25.7 24.7 26.0 57.0 71.5 35.1 39.2 46.7 33.5 37.7 29.7 49.7 23.7 30.9 35.3 42.5 43.6 21.0 40.7 54.4 111.8 76.2 68.4 48.0 43.8 24.0 29.2 16.0 13.2 12.3 19.0 12.5 14.4 13.7 12.9 17.0 14.5 14.5 14.8 6.6 20.9 17.7 11.1 18.2 17.4 10.4 11.8 12.7 16.7 12.2 12.2 12.4 10.2 13.2 10.3 11.2 14.1 21.3 22.4 24.8 40.8 26.7 22.9 9.1 16.0 31.9 16.8 15.7 10.8 63.5 11.5 12.9 20.2 22.9 21.7 18.0 34.8 19.6 18.1 238.9 10.4 20.1 18.9 23.4 29.9 73.3 25.6 18.2 22.6 34.7 12.1 19.0 16.2 26.7 43.9 27.2 18.5 63.9 28.3 32.6 26.1 21.0 448.2 21.1 23.9 30.2 31.9 28.1 21.9 17.5 49.8 91.8 18.9 22.8 22.2 73.8 8.0 26.5 41.7 14.9 14.1 19.7 18.5 22.6 23.3 14.2 30.0 26.9 20.5 23.9 22.7 24.0 6.8 SLC25A47 C14orf68 ENSG00000140107 "Solute carrier family 25 member 47" Q6Q0C1 14 100323339-100330421 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 355 "liver: 534.7" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 270.2" "Cancer enriched" "Detected in single" 273 "liver cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.54e-3)" "unprognostic (2.57e-3)" "unprognostic (5.12e-2)" "unprognostic (2.27e-2)" "unprognostic (6.07e-2)" "unprognostic (1.30e-2)" "unprognostic (4.25e-2)" "unprognostic (1.14e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (1.96e-3)" "unprognostic (4.46e-1)" "unprognostic (1.44e-1)" "unprognostic (4.50e-1)" "unprognostic (5.64e-2)" "unprognostic (1.02e-2)" "unprognostic (1.94e-1)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 534.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.1 0.0 2.7 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.9 270.2 0.0 0.0 0.0 0.6 0.0 6.7 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 3.5 3.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.1 SLC25A48 "FLJ44862, HDMCP" ENSG00000145832 "Solute carrier family 25 member 48" Q6ZT89 5 135579202-135889770 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.2;skeletal muscle: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 31.0;Distal tubular cells: 9.8;Proximal enterocytes: 11.1;Proximal tubular cells: 45.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.7;HEK 293: 2.0;HEL: 1.7;RPMI-8226: 1.9;SCLC-21H: 1.9;U-2 OS: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014674 Uncertain Approved "Intermediate filaments,Actin filaments" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Intermediate filaments" "Actin filaments" "HPA014674: AB_1859512" "unprognostic (2.09e-1)" "unprognostic (2.24e-1)" "unprognostic (6.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.96e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-7)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" 0.9 0.1 13.5 0.3 14.4 0.2 1.1 10.9 16.4 0.3 4.8 0.9 0.7 0.2 0.1 0.4 0.1 0.2 0.2 14.4 17.7 7.5 0.5 0.0 0.3 14.7 18.0 0.1 2.1 0.0 0.1 0.4 17.5 0.4 0.9 0.5 1.7 0.0 8.8 1.9 2.4 0.1 16.8 0.2 0.1 0.4 18.3 0.0 0.2 2.3 0.1 0.1 0.2 28.2 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.2 2.7 0.0 0.0 0.3 2.0 1.7 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 1.9 0.1 0.2 1.9 0.2 0.3 0.2 0.4 0.7 1.0 0.2 0.1 0.1 2.3 0.1 0.1 0.8 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 13.5 14.4 10.9 16.4 14.4 17.7 14.7 18.0 17.5 16.8 18.3 28.2 0.1 0.0 0.0 31.0 0.0 2.4 0.1 0.0 0.0 0.2 2.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.0 9.8 0.0 0.0 2.0 1.2 0.1 0.0 0.0 0.6 0.0 0.2 0.7 0.0 7.1 0.0 0.0 0.0 1.3 0.1 0.0 3.1 2.8 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.2 0.0 5.0 4.2 0.1 5.0 0.0 0.0 0.3 11.1 45.8 0.0 0.2 0.0 0.5 0.1 0.5 4.3 0.0 0.9 0.1 0.1 0.0 1.6 0.1 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 8.9" "Group enriched" "Detected in some" 4 "Early spermatids: 55.3;Late spermatids: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (8.97e-2)" "unprognostic (4.85e-2)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (2.50e-1)" "unprognostic (9.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.30e-4)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC25A53 MCART6 ENSG00000269743 "Solute carrier family 25 member 53" Q5H9E4 X 104099214-104157009 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Daudi: 6.1;Karpas-707: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034959 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA034959: AB_10602025" "unprognostic (4.70e-2)" "unprognostic (1.16e-2)" "unprognostic (7.16e-3)" "unprognostic (5.94e-2)" "unprognostic (2.68e-2)" "unprognostic (5.23e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" "unprognostic (4.45e-3)" "unprognostic (7.94e-2)" "unprognostic (9.76e-5)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (3.48e-2)" "unprognostic (1.74e-1)" "unprognostic (3.53e-1)" "unprognostic (1.76e-2)" 0.1 0.3 1.0 1.0 1.0 0.4 0.2 1.3 1.1 0.2 0.3 0.2 0.4 0.2 0.2 0.1 0.2 0.3 0.3 1.1 0.9 0.1 0.1 0.2 1.9 0.9 1.1 0.4 0.5 0.1 0.2 0.1 0.9 0.2 0.4 0.4 0.1 0.1 0.1 0.2 1.0 0.2 1.0 1.3 0.4 0.6 1.0 0.5 0.1 0.0 1.6 0.2 0.1 1.3 0.0 0.1 1.7 1.1 0.1 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 6.1 0.1 0.0 0.3 0.1 2.0 0.0 0.1 0.5 0.8 0.7 0.2 0.1 0.1 1.1 0.7 0.3 0.0 0.2 0.0 0.3 0.4 0.6 0.1 13.9 0.1 0.1 0.2 0.1 2.2 0.1 0.4 2.5 0.9 0.2 0.3 0.2 1.5 2.1 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.8 0.1 0.4 0.1 0.0 2.2 0.1 1.6 0.4 0.2 0.1 0.2 0.3 0.1 0.6 0.5 0.3 0.5 0.1 0.4 0.0 0.3 0.7 0.2 0.0 0.0 0.5 0.1 1.0 1.0 1.3 1.1 1.1 0.9 0.9 1.1 0.9 1.0 1.0 1.3 6.6 6.4 4.6 26.4 11.4 5.2 8.8 6.2 4.0 3.5 7.2 5.7 15.1 5.7 4.6 9.2 0.0 3.7 9.6 17.3 25.4 4.3 6.8 6.9 4.7 5.3 7.2 19.4 15.5 6.0 4.2 7.6 7.7 7.2 7.0 2.7 6.4 25.1 10.6 3.3 14.1 7.8 4.1 8.8 5.7 1.3 3.1 7.5 1.8 16.9 11.4 4.0 17.5 17.1 23.5 7.8 21.8 3.0 10.2 8.8 19.7 25.9 10.8 8.1 0.0 5.2 5.0 4.8 2.3 4.7 5.7 6.2 11.0 3.0 4.5 11.3 SLC25A6 "ANT3, ANT3Y, MGC17525" ENSG00000169100 "Solute carrier family 25 member 6" P12236 X 1386152-1392113 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Apoptosis, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.13e-1)" "unprognostic (1.65e-2)" "unprognostic (4.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-3)" "unprognostic (1.34e-1)" "unprognostic (8.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (4.57e-3)" 356.6 410.1 227.8 223.3 241.4 441.5 307.3 210.8 296.7 253.7 351.6 350.9 466.0 277.9 80.6 344.8 243.4 127.2 201.5 227.9 216.1 386.8 130.0 239.4 275.0 222.6 222.8 460.8 626.9 323.5 275.8 147.1 228.0 264.1 141.5 108.3 697.7 178.8 115.5 331.3 387.7 129.4 208.3 263.7 413.9 62.2 227.4 232.7 321.5 89.2 159.3 292.0 244.6 219.2 290.4 596.8 393.8 422.6 267.5 527.4 466.2 396.8 386.1 296.8 289.2 796.7 330.6 1023.0 334.1 264.9 445.6 179.2 269.5 482.0 89.8 260.3 886.0 545.0 396.0 899.7 642.2 398.1 649.8 870.1 882.2 235.8 335.9 367.5 441.6 315.7 407.2 233.8 284.5 575.4 791.1 733.3 516.0 105.5 802.2 378.8 333.8 828.3 351.4 693.6 682.9 1096.5 271.1 817.7 1239.7 224.1 466.1 832.5 505.5 305.1 169.6 596.5 422.1 606.7 110.5 705.9 48.7 389.9 170.3 34.2 739.8 47.2 319.5 808.7 466.9 671.4 431.3 377.9 985.9 532.5 396.1 399.7 34.4 359.9 832.3 461.2 447.6 1120.7 227.8 241.4 210.8 296.7 227.9 216.1 222.6 222.8 228.0 208.3 227.4 219.2 194.2 147.4 244.3 13.7 724.4 1151.2 1447.6 1800.6 421.8 286.1 981.3 710.8 106.0 371.8 704.7 316.3 98.0 1581.2 448.5 690.4 1659.2 752.6 11.4 164.4 388.1 473.0 928.4 471.3 15.1 1473.5 1229.8 507.8 374.1 245.3 343.6 698.0 529.4 149.7 1264.7 242.3 20.4 1208.1 819.9 1553.5 1299.4 45.8 667.9 764.0 754.2 17.8 1450.5 184.6 531.4 8.0 13.7 789.8 1127.8 366.3 604.9 1452.4 1564.9 1320.8 180.3 280.0 341.8 631.7 665.6 13.3 80.7 796.7 1321.5 1744.1 494.7 847.8 1524.3 1723.2 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC26A4 "DFNB4, PDS" ENSG00000091137 "Solute carrier family 26 member 4" O43511 7 107660828-107717809 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "thyroid gland: 263.7" "Cell type enhanced" "Detected in many" "Club cells: 19.0;Excitatory neurons: 29.3;Inhibitory neurons: 53.9;Ionocytes: 54.9;Prostatic glandular cells: 17.3;Urothelial cells: 19.9" "Cancer enriched" "Detected in some" 8 "thyroid cancer: 37.6" "Group enriched" "Detected in many" 88 "amygdala: 4.0;basal ganglia: 10.2;cerebral cortex: 11.8;hippocampal formation: 8.8" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 8 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;hTERT-RPE1: 3.7;LHCN-M2: 2.1" "Region enriched" "Detected in many" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "hippocampal formation: 4.8" HPA042860 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042860: AB_10796680" "unprognostic (1.19e-2)" "unprognostic (4.84e-2)" "unprognostic (5.44e-2)" "unprognostic (8.44e-2)" "unprognostic (3.25e-2)" "unprognostic (3.26e-2)" "unprognostic (6.69e-2)" "unprognostic (1.85e-1)" "unprognostic (5.72e-2)" "unprognostic (9.58e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-2)" "unprognostic (1.39e-1)" 0.4 0.1 4.0 0.1 10.2 0.0 0.8 0.0 11.8 1.4 0.0 0.2 0.1 0.5 0.1 0.1 0.3 0.4 0.6 8.8 0.0 6.4 0.1 0.5 0.4 0.0 0.0 0.3 0.3 3.9 0.3 0.3 0.0 3.8 0.2 0.1 0.4 0.2 0.5 0.2 0.1 0.3 0.0 0.1 0.7 0.6 0.0 0.2 263.7 0.1 0.2 1.5 0.3 0.0 0.3 0.1 0.2 0.0 0.3 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 0.2 0.0 0.0 1.6 0.4 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.4 0.2 0.0 3.7 0.0 0.3 0.0 0.1 2.1 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.3 0.3 0.2 0.1 1.3 0.3 0.3 0.1 0.3 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 10.2 0.0 11.8 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.2 7.7 2.6 0.2 1.7 0.7 6.5 0.0 6.6 3.2 1.8 0.6 0.0 19.0 0.0 2.1 0.3 0.4 0.4 0.0 0.2 3.9 0.3 0.5 4.9 7.3 0.0 29.3 0.0 0.1 1.5 0.0 1.8 5.1 0.2 1.1 0.2 0.3 1.7 53.9 0.0 54.9 0.6 2.0 2.7 0.9 0.7 7.2 3.7 0.7 1.2 1.0 1.5 1.6 0.1 0.1 1.2 0.0 17.3 0.0 0.1 15.2 1.8 0.0 2.9 1.6 2.0 0.4 0.1 1.4 0.0 1.7 0.2 0.5 19.9 SLC26A6 DKFZp586E1422 ENSG00000225697 "Solute carrier family 26 member 6" Q9BXS9 3 48625723-48635493 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.7;Intestinal goblet cells: 34.0;Paneth cells: 40.9;Proximal enterocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048363 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA048363: AB_2680371" "unprognostic (1.54e-1)" "unprognostic (4.94e-2)" "unprognostic (3.34e-1)" "unprognostic (3.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.92e-4)" "unprognostic (2.39e-1)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (9.66e-3)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.58e-2)" 5.6 6.8 4.8 5.2 5.2 18.1 5.5 5.1 6.5 9.3 5.4 28.0 8.2 7.4 3.6 5.2 6.6 3.7 8.1 4.7 5.0 19.6 7.6 9.5 3.9 5.6 5.1 7.3 11.4 3.6 5.5 5.5 5.9 12.4 21.6 4.1 5.8 4.2 9.5 6.7 22.4 5.6 5.2 12.5 26.8 5.6 5.6 3.8 6.3 6.1 3.2 6.6 7.9 6.2 8.5 8.9 13.2 15.0 39.9 19.8 11.2 13.7 17.7 25.8 27.4 17.6 7.6 12.0 4.6 11.6 28.7 11.2 12.1 12.5 7.2 9.3 12.0 10.8 29.6 34.3 29.4 5.2 16.5 27.4 44.0 17.7 12.4 22.1 8.0 12.4 8.6 13.2 6.2 9.8 10.4 27.0 18.5 23.0 17.9 5.2 4.8 14.5 18.8 7.9 3.3 6.2 17.7 21.3 25.2 17.9 11.2 19.2 6.9 11.6 9.2 15.0 31.7 15.7 17.8 5.6 9.7 20.5 28.4 6.8 11.1 2.3 3.0 10.8 2.7 0.9 1.8 1.9 9.0 0.2 1.0 1.5 1.5 0.6 10.1 5.1 3.4 5.0 4.8 5.2 5.1 6.5 4.7 5.0 5.6 5.1 5.9 5.2 5.6 6.2 4.3 3.2 5.9 10.7 2.1 3.2 2.6 8.0 5.7 2.1 3.8 2.7 6.6 1.5 3.8 1.8 14.6 9.3 2.4 69.7 0.0 2.9 1.2 1.3 3.2 5.1 20.4 4.0 2.0 6.3 15.0 4.0 13.3 2.7 0.0 3.1 4.2 6.3 7.0 5.0 2.1 34.0 10.2 5.3 7.4 0.9 3.7 6.3 5.4 1.9 5.8 1.6 6.2 2.5 2.5 5.8 40.9 9.4 5.8 2.0 43.6 6.2 3.7 6.9 0.0 1.3 4.5 2.9 6.9 2.4 3.4 10.5 3.8 13.5 26.8 1.0 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cell line enhanced" "Detected in many" "ASC diff: 53.3;MCF7: 30.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA006935, HPA067508" Enhanced Enhanced "Endoplasmic reticulum" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA006935: AB_1080003, HPA067508: AB_2685857" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (2.70e-2)" "unprognostic (4.85e-2)" "unprognostic (6.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (3.39e-2)" "prognostic favorable (5.23e-4)" "unprognostic (4.67e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.95e-1)" "unprognostic (4.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.08e-1)" 18.9 5.0 4.1 3.3 4.1 2.5 17.7 3.3 5.7 8.3 4.6 8.8 2.4 6.3 37.7 6.1 9.8 5.7 8.3 4.0 4.1 11.1 20.4 19.0 4.7 4.2 5.6 9.2 8.0 9.2 9.9 6.4 3.9 7.1 5.0 0.6 5.1 8.0 3.1 12.3 7.7 5.8 3.6 8.6 19.3 12.2 3.9 2.3 9.4 3.7 2.8 7.4 9.5 4.0 2.6 0.5 3.1 1.5 53.3 10.8 0.8 0.5 3.9 1.2 1.0 1.8 1.8 1.1 1.6 2.4 0.6 9.3 3.0 1.5 0.7 0.4 1.4 1.5 2.8 1.9 6.7 1.4 5.8 5.5 6.6 0.3 1.4 1.1 7.0 0.3 0.8 1.4 0.3 30.8 0.3 8.1 3.4 12.2 1.4 8.6 0.6 0.9 1.5 0.9 2.7 1.7 0.6 9.6 3.0 4.1 3.9 5.5 0.0 1.5 2.8 3.3 0.1 2.4 2.4 0.3 2.5 5.7 1.2 9.5 10.7 12.6 2.1 8.8 1.3 0.6 0.6 2.1 7.4 0.7 0.2 0.6 0.9 2.5 11.1 1.0 0.2 3.4 4.1 4.1 3.3 5.7 4.0 4.1 4.2 5.6 3.9 3.6 3.9 4.0 47.3 19.2 51.8 6.5 5.5 11.7 12.6 9.0 8.0 0.9 4.4 11.3 4.6 34.3 10.1 3.7 0.0 27.2 20.7 4.2 0.0 4.3 0.6 5.1 12.1 42.4 4.2 0.4 2.6 7.3 13.0 20.3 16.8 7.9 25.4 1.8 106.1 30.6 33.2 1.7 2.6 23.7 6.1 31.7 39.8 3.2 19.0 21.3 23.2 1.9 44.6 2.0 35.0 0.5 1.6 3.1 42.3 14.3 7.9 3.4 2.5 3.6 6.6 1.0 6.6 3.4 15.7 1.7 2.9 5.5 7.7 8.8 13.0 5.2 10.7 7.0 SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.7;Proximal enterocytes: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" 11.4 14.7 22.5 8.5 23.7 2.7 11.6 25.4 30.3 17.2 12.4 22.8 66.9 14.4 6.3 61.8 10.4 7.3 20.4 22.7 25.9 28.8 40.0 11.8 6.4 29.4 23.9 8.3 21.6 15.5 12.1 5.6 28.8 13.1 9.4 6.8 16.4 7.5 16.1 41.8 41.1 9.3 19.7 11.6 16.4 25.8 27.1 5.8 15.5 6.2 9.6 15.5 23.5 24.1 20.8 41.8 21.1 28.1 31.5 9.8 23.3 16.7 11.7 20.3 14.5 30.1 20.7 19.1 13.5 19.8 24.8 70.6 25.5 20.7 6.7 19.5 37.2 11.4 35.6 28.5 17.1 21.0 17.8 12.7 29.6 21.2 17.0 9.4 23.1 26.3 27.5 13.7 20.2 56.2 26.0 22.7 9.2 51.6 63.0 30.4 19.6 36.4 38.1 32.0 34.8 19.2 27.6 57.0 20.3 11.3 26.7 8.8 32.4 23.7 22.9 26.6 22.0 11.4 17.4 6.5 24.3 13.0 27.7 0.0 2.5 1.7 4.7 3.3 3.4 2.1 2.9 3.6 4.4 0.9 2.3 2.4 1.0 1.4 4.3 3.9 2.2 2.4 22.5 23.7 25.4 30.3 22.7 25.9 29.4 23.9 28.8 19.7 27.1 24.1 4.7 0.0 1.1 12.7 2.0 2.8 1.4 4.0 1.2 9.6 5.8 3.0 5.2 7.2 2.8 9.2 12.5 6.1 2.1 53.7 1.9 13.1 4.8 3.6 5.2 5.3 13.1 4.0 27.7 16.0 6.8 3.5 14.3 9.3 8.9 5.9 3.6 20.1 11.3 8.4 29.2 18.6 8.2 6.1 1.9 5.4 1.2 5.4 1.8 15.9 10.0 5.0 6.2 8.5 26.4 26.4 30.0 4.1 3.2 3.2 100.6 9.7 1.8 7.8 6.6 4.4 4.4 11.8 7.9 11.9 6.1 5.2 2.4 7.9 25.7 2.8 SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 24.4;fallopian tube: 21.3;heart muscle: 23.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 25.0;Cardiomyocytes: 29.6;Cytotrophoblasts: 54.8;Extravillous trophoblasts: 37.3;Muller glia cells: 33.0;Skeletal myocytes: 18.0;Syncytiotrophoblasts: 27.5" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 43.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" "HPA008987: AB_1857065" "unprognostic (5.39e-5)" "unprognostic (4.79e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-1)" "unprognostic (3.55e-1)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" "unprognostic (2.14e-1)" "unprognostic (2.54e-2)" "unprognostic (9.66e-4)" 0.4 24.4 1.8 0.3 2.4 0.1 3.0 3.0 1.4 3.9 0.7 0.9 0.4 4.3 0.2 4.2 21.3 2.7 23.5 1.2 3.6 0.0 0.1 0.8 0.2 9.7 5.2 9.7 0.1 0.0 6.0 6.7 7.5 3.6 1.7 7.4 3.5 0.3 0.4 2.0 1.1 0.8 5.8 0.1 0.5 13.0 5.5 9.6 1.8 0.9 5.7 1.1 2.9 8.4 0.0 0.0 0.1 0.0 0.0 0.0 43.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.9 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 3.5 0.0 3.3 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.3 4.4 0.0 5.1 0.0 3.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 3.0 1.4 1.2 3.6 9.7 5.2 7.5 5.8 5.5 8.4 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 25.0 0.6 0.2 5.5 29.6 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 13.2 3.8 1.0 0.3 0.0 0.0 0.4 0.0 37.3 2.7 0.0 1.9 0.0 1.7 0.0 0.0 3.8 3.3 4.6 0.0 0.0 0.0 0.4 2.8 0.3 0.2 0.0 0.0 0.0 33.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.9 0.0 18.0 0.3 1.1 1.0 1.8 0.9 27.5 0.0 2.3 0.1 0.1 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 216.6;Extravillous trophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1046.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" 76.4 95.8 10.2 22.3 10.2 53.4 50.4 13.0 14.8 25.4 4.5 59.7 13.1 37.3 15.9 25.3 34.5 44.2 119.7 10.1 12.2 17.8 57.9 33.1 25.9 13.2 10.2 12.9 91.2 22.8 22.6 58.8 15.3 16.5 17.8 21.1 35.6 19.3 144.5 53.0 17.2 46.2 9.5 14.5 53.7 14.9 10.7 81.3 30.7 100.7 17.0 32.8 17.7 10.8 85.3 84.2 58.5 95.1 87.8 8.1 347.1 61.2 24.0 83.6 57.4 91.8 34.8 171.2 60.8 18.5 51.7 103.8 105.2 72.8 51.9 97.6 97.2 150.5 57.8 122.5 14.1 170.3 139.7 10.9 18.4 123.0 42.7 171.6 216.0 137.2 205.4 100.1 46.9 94.0 142.0 114.4 89.0 218.4 55.4 94.0 117.8 208.9 49.1 49.5 75.0 97.0 18.4 58.9 43.9 61.5 80.7 107.1 333.1 46.4 74.8 62.6 117.7 67.0 93.8 221.9 28.8 136.8 57.1 21.9 12.1 1046.6 5.1 38.8 4.2 4.4 2.7 3.9 6.8 2.4 1.1 2.4 1.8 3.1 32.5 40.0 8.2 6.6 10.2 10.2 13.0 14.8 10.1 12.2 13.2 10.2 15.3 9.5 10.7 10.8 64.2 0.0 10.5 1.3 4.0 10.7 9.0 4.1 2.2 10.9 20.2 30.1 46.4 17.2 6.0 7.3 14.6 216.6 5.7 3.0 3.9 24.2 0.5 4.3 3.5 31.7 31.2 49.2 18.4 56.7 224.6 40.0 26.5 11.2 8.2 25.4 25.7 16.7 63.6 5.0 25.4 2.9 79.3 37.0 13.3 2.8 32.9 19.2 35.6 16.9 8.3 4.3 0.0 5.0 2.6 61.9 3.4 53.8 14.2 18.2 0.7 0.9 6.9 11.9 92.1 21.0 22.5 0.4 11.0 4.6 15.6 42.0 3.2 4.1 6.2 9.8 SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.3;choroid plexus: 55.5" "Group enriched" "Detected in many" 5 "Enteroendocrine cells: 103.2;Horizontal cells: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.2;SH-SY5Y: 70.7;U-2 OS: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" 43.3 8.2 13.2 0.7 16.2 0.6 13.3 16.0 20.0 4.9 55.5 3.1 4.6 5.4 5.0 1.1 4.0 1.6 3.7 26.3 28.5 7.9 9.2 0.9 0.2 23.2 26.1 2.2 15.4 1.7 3.6 0.6 23.6 5.8 1.8 4.1 1.3 0.7 2.6 3.0 5.5 1.8 17.2 1.6 6.5 2.6 30.0 0.3 9.7 0.4 0.1 2.4 2.0 7.4 0.0 21.7 12.6 49.2 0.6 0.2 2.4 1.8 0.1 1.6 0.9 12.3 0.4 0.0 2.4 1.9 8.1 0.3 4.8 0.4 0.5 0.1 2.8 0.2 0.7 18.3 3.8 0.2 3.0 1.5 16.2 0.3 0.9 2.9 1.5 4.5 3.6 0.1 1.2 10.8 2.0 0.9 16.0 1.5 1.3 8.3 2.1 1.9 3.2 0.5 8.4 70.7 1.3 4.4 0.9 10.7 5.5 5.9 0.7 17.3 23.4 1.6 0.5 1.1 0.0 0.1 2.2 0.7 8.0 0.8 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.1 0.4 0.2 0.2 1.3 1.6 0.1 0.3 0.1 0.1 13.2 16.2 16.0 20.0 26.3 28.5 23.2 26.1 23.6 17.2 30.0 7.4 0.5 3.2 0.5 8.8 0.0 0.1 0.2 0.1 0.0 6.9 0.7 0.6 2.5 0.0 0.2 0.0 16.7 0.3 0.2 6.3 0.0 5.3 0.1 3.3 3.0 0.6 103.2 0.0 2.4 0.2 0.4 2.2 2.0 0.7 0.0 25.7 0.0 1.0 0.4 168.2 14.3 4.4 0.0 0.3 0.7 0.7 0.3 0.3 0.0 0.0 0.1 4.8 0.0 4.0 0.6 1.4 0.5 0.4 0.1 2.3 0.8 0.2 1.4 1.6 0.0 0.5 2.2 0.4 4.2 0.1 0.3 0.3 0.3 1.7 1.0 0.2 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 457.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "CACO-2: 7.7;Hep G2: 27.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860" "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.4 0.0 0.2 0.0 66.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.3 30.8 836.1 0.0 0.0 0.5 0.4 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 27.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.4 0.3 0.3 0.5 0.4 0.8 0.4 0.4 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 90.1 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 6.7 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 457.6 0.0 0.0 0.1 3.0 0.0 10.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 2.5 0.0 0.0 0.0 105.4 63.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.8 0.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC2A6 "GLUT6, GLUT9, HSA011372" ENSG00000160326 "Solute carrier family 2 member 6" Q9UGQ3 9 133471094-133479127 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;granulocytes: 47.4;monocytes: 60.4;Paneth cells: 39.8;Rod photoreceptor cells: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 33.1;HMC-1: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042272, CAB046014" Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB046014: AB_2270444, HPA042272: AB_2677924" "unprognostic (2.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (1.71e-3)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.93e-2)" "unprognostic (1.05e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (1.02e-11)" "unprognostic (7.24e-2)" "unprognostic (3.43e-2)" "unprognostic (9.36e-2)" "unprognostic (6.28e-3)" 4.0 3.8 5.9 4.6 5.7 4.3 2.9 6.6 9.2 1.3 2.5 2.4 0.9 2.5 0.7 1.1 1.5 0.8 4.7 5.7 7.4 3.9 3.5 8.4 4.1 11.9 7.1 0.9 2.7 0.5 2.3 0.7 11.9 1.9 0.4 0.6 1.5 0.4 1.1 1.0 6.7 0.9 4.7 13.3 2.5 1.6 8.1 0.5 1.8 0.3 2.3 4.5 1.4 6.1 5.7 9.6 3.2 9.4 1.8 2.7 2.8 5.2 8.5 4.9 5.2 4.3 7.5 4.5 14.0 4.8 23.3 8.3 2.0 5.7 1.1 33.1 1.9 5.5 6.8 5.2 6.3 0.1 67.8 3.7 0.9 7.2 0.8 0.3 5.0 5.3 0.8 4.3 3.4 12.4 2.9 5.3 4.8 2.2 12.0 2.3 5.8 23.3 6.8 14.5 4.0 5.5 8.2 3.9 2.6 1.7 14.9 2.4 13.9 12.3 5.0 14.0 4.2 2.4 2.0 6.3 3.2 1.3 2.8 46.3 18.2 1.8 1.6 36.9 1.1 9.3 0.3 1.1 16.3 8.8 0.5 1.3 0.9 1.2 73.2 17.3 0.2 9.3 5.9 5.7 6.6 9.2 5.7 7.4 11.9 7.1 11.9 4.7 8.1 6.1 6.2 3.2 4.1 9.1 24.6 0.4 1.2 17.3 0.6 25.9 1.1 0.1 1.8 5.7 6.2 3.7 52.1 0.4 31.3 2.8 0.0 36.0 6.0 1.2 1.1 9.6 3.6 0.4 21.7 8.9 0.7 2.6 5.1 1.9 47.4 1.2 2.5 0.6 4.5 23.5 15.6 2.4 2.0 15.6 10.3 2.4 0.9 30.6 3.6 1.9 60.4 5.6 4.1 3.5 6.9 21.5 39.8 0.0 10.8 1.0 1.9 0.3 3.3 46.0 32.9 3.8 7.6 2.2 6.8 0.2 0.4 0.3 5.5 5.2 2.3 0.6 SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Endometrial stromal cells: 86.5;Late spermatids: 310.1;Spermatocytes: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 75.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 75.9" "Cell line enhanced" "Detected in many" "CACO-2: 122.9;Hep G2: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favorable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favorable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favorable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" 17.3 46.9 23.0 7.5 24.8 3.4 13.1 22.5 22.7 19.7 14.6 42.1 15.7 16.5 13.4 12.0 11.1 6.4 18.2 20.9 18.4 15.4 41.0 11.5 7.4 23.6 23.3 12.0 12.4 6.3 9.9 11.6 20.9 17.8 5.3 3.1 10.2 11.6 33.1 14.2 15.5 6.0 23.5 16.7 23.1 64.2 22.8 1.6 14.8 12.7 3.6 60.6 12.8 25.5 4.9 18.8 8.4 18.5 0.0 0.0 26.3 7.4 4.9 11.5 6.9 122.9 4.5 7.5 16.3 3.9 18.4 25.4 10.1 11.7 2.9 7.2 16.2 1.1 15.4 73.3 10.5 0.0 7.8 0.2 10.6 1.1 4.7 5.7 9.0 10.2 8.1 16.4 4.7 35.1 0.0 0.2 13.4 27.1 29.4 2.9 11.5 20.7 11.0 50.6 13.8 9.6 17.6 29.8 6.6 10.6 19.2 4.3 7.9 0.0 11.7 0.8 16.7 49.7 50.6 11.3 7.8 0.0 8.9 0.0 7.0 16.6 10.4 13.5 7.7 5.0 3.3 7.1 10.6 4.7 0.7 2.5 0.5 3.3 12.5 75.9 15.0 4.7 23.0 24.8 22.5 22.7 20.9 18.4 23.6 23.3 20.9 23.5 22.8 25.5 10.8 9.6 8.4 6.2 6.4 11.1 7.4 8.5 9.6 9.5 12.2 10.7 7.6 8.6 7.8 5.5 10.4 78.3 24.5 12.5 15.6 15.6 145.8 6.0 86.5 10.2 12.1 7.0 7.7 16.7 12.8 11.0 10.7 8.0 7.0 15.9 12.1 26.8 75.0 6.7 7.7 14.9 2.0 16.7 8.5 310.1 10.8 14.9 26.6 2.8 7.2 13.4 13.4 2.0 5.4 17.4 22.3 11.7 8.5 14.1 35.0 14.0 5.3 8.4 13.1 11.6 8.6 98.7 15.5 8.7 10.5 67.3 5.9 9.3 19.8 5.8 SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.4;Early spermatids: 17.8;Excitatory neurons: 15.6;Late spermatids: 42.4;Peritubular cells: 15.1;Spermatocytes: 16.6;Spermatogonia: 10.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HAP1: 11.2;Hep G2: 12.0;REH: 22.8;RH-30: 11.0" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" 0.1 2.1 14.5 0.1 10.3 0.3 0.1 0.0 18.2 0.2 0.0 0.1 0.0 0.4 68.5 0.1 0.3 0.1 7.9 22.2 0.0 0.1 0.2 0.2 0.5 0.5 0.0 0.2 0.0 0.5 0.3 0.0 0.8 0.3 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 35.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 1.5 0.4 1.3 0.1 2.0 0.2 0.2 0.3 0.0 0.0 1.3 1.4 0.5 0.5 0.0 0.1 0.0 8.8 0.3 11.2 0.0 0.3 0.0 1.2 5.9 0.5 12.0 0.2 0.2 2.3 0.0 0.0 0.6 0.0 0.2 0.9 2.9 1.7 0.1 0.2 3.9 0.1 0.4 1.8 0.4 0.0 22.8 11.0 1.4 0.0 0.3 0.0 0.7 2.8 0.0 0.0 0.1 0.0 0.8 0.1 0.3 5.1 0.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 14.5 10.3 0.0 18.2 22.2 0.0 0.5 0.0 0.8 0.0 0.0 1.5 0.3 0.0 0.0 2.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 17.8 0.0 0.1 0.4 0.0 0.0 15.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 42.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 15.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 16.6 10.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093949-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA035373: AB_10794630" "unprognostic (9.81e-3)" "unprognostic (3.33e-1)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.47e-2)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" 25.8 25.6 9.8 21.0 10.3 19.6 30.3 11.7 15.9 29.7 17.4 26.9 24.7 25.6 38.2 19.3 24.3 24.0 24.1 9.7 10.6 29.1 29.0 21.1 24.7 10.1 11.4 22.3 33.0 35.9 24.0 27.4 10.2 29.4 24.7 18.5 30.8 24.0 16.4 27.1 23.6 22.8 9.7 21.9 26.3 16.4 10.9 20.8 37.5 16.5 23.7 23.6 19.7 12.1 37.4 29.9 26.3 46.2 69.1 53.2 82.5 58.8 53.6 36.4 55.1 26.0 45.7 50.2 70.6 41.4 63.7 38.8 38.6 46.1 61.5 60.2 43.5 55.7 35.0 43.2 55.0 34.8 58.3 35.7 57.1 38.3 46.5 50.1 36.6 34.2 34.9 57.0 46.1 46.9 46.4 71.6 29.4 25.3 33.3 35.5 33.2 89.9 53.6 34.5 46.0 36.8 47.4 45.0 84.5 36.0 43.7 76.2 33.3 23.2 29.5 58.7 58.2 49.5 67.5 37.9 46.6 62.3 58.9 11.9 5.1 8.5 4.1 5.3 4.4 6.9 6.4 6.2 6.3 4.3 5.9 4.8 4.1 4.0 5.5 9.6 4.9 2.8 9.8 10.3 11.7 15.9 9.7 10.6 10.1 11.4 10.2 9.7 10.9 12.1 17.3 19.2 21.5 14.7 26.9 18.7 27.9 27.5 19.9 15.3 28.5 20.6 29.2 18.6 23.2 25.8 22.9 42.0 35.3 19.9 29.4 22.0 6.9 28.8 35.8 19.3 13.2 29.9 29.6 27.1 80.4 24.8 34.7 23.7 41.3 15.4 21.8 19.8 22.3 8.4 30.6 27.9 32.6 17.2 18.4 9.9 24.2 16.8 14.2 19.7 21.2 14.9 15.5 22.1 23.3 19.0 16.7 22.2 51.8 34.7 16.9 21.3 27.7 24.7 26.3 17.5 21.4 11.0 14.9 26.6 21.5 51.6 23.4 20.9 23.2 28.6 SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 61.8" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Late spermatids: 7.5;Pancreatic endocrine cells: 5.0;Proximal tubular cells: 3.6;Spermatogonia: 5.0" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "U-266/70: 48.0;U-266/84: 36.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 4.1" HPA076165 Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA076165: AB_2732304" "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" 0.0 0.0 0.3 0.0 0.4 0.3 0.6 0.2 0.2 0.1 0.0 0.3 0.6 0.7 0.0 0.2 0.1 0.2 0.2 0.3 0.2 4.3 0.0 0.1 0.1 0.2 0.1 0.0 61.8 0.3 0.3 0.3 0.3 0.1 0.2 0.2 12.9 0.0 0.0 0.8 1.0 0.2 0.0 0.0 1.1 2.0 0.1 0.1 0.1 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 48.0 36.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.2 0.3 0.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 4.9 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.8 5.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.0" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA013810: AB_1857095" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (5.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (1.22e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.51e-2)" 11.5 23.9 5.7 11.1 5.8 11.7 12.7 6.6 6.5 20.7 26.3 16.3 45.1 7.2 13.7 12.0 6.5 9.6 7.4 6.9 6.6 28.7 107.6 17.7 6.3 7.2 6.9 4.9 19.1 15.2 5.8 13.5 11.7 21.3 17.0 7.1 66.5 12.8 3.5 18.5 37.4 10.0 6.8 7.6 19.4 6.4 7.0 5.5 10.9 5.8 12.4 14.3 6.5 6.5 22.1 23.4 18.7 41.4 42.0 29.8 68.8 38.3 58.0 26.0 30.1 33.5 18.8 17.2 15.2 33.0 32.9 53.3 35.8 21.8 29.0 15.2 19.9 14.2 18.7 37.6 102.3 26.1 20.6 36.1 48.3 33.6 54.6 17.4 24.0 19.6 32.8 30.9 24.8 23.6 17.9 13.2 30.4 84.2 26.0 18.3 49.1 17.2 23.6 27.2 17.7 23.1 37.0 73.0 101.5 26.2 37.2 22.0 22.3 19.3 11.9 39.1 23.2 18.5 40.5 23.6 31.9 24.2 23.1 3.0 20.9 2.5 2.3 26.8 3.2 1.7 1.6 2.4 16.3 1.5 1.8 1.7 8.2 4.4 31.0 2.3 1.8 7.6 5.7 5.8 6.6 6.5 6.9 6.6 7.2 6.9 11.7 6.8 7.0 6.5 8.0 35.3 33.5 7.5 6.6 15.2 10.6 27.4 10.2 12.6 21.4 14.9 7.4 21.5 50.8 5.5 33.3 16.5 6.9 40.2 9.8 18.3 0.3 16.2 15.6 11.6 9.0 25.4 16.8 27.2 24.1 16.0 15.3 14.5 5.1 11.4 11.4 97.1 43.4 6.7 17.0 18.9 42.7 39.4 19.9 0.9 6.2 40.3 12.4 20.6 21.8 12.2 4.1 16.1 12.3 22.3 11.1 7.2 16.1 28.9 61.7 24.7 30.1 11.2 6.6 8.4 15.2 24.4 30.7 15.1 15.8 22.4 5.5 15.2 19.9 22.6 SLC33A1 "ACATN, AT-1, AT1, SPG42" ENSG00000169359 "Solute carrier family 33 member 1" O00400 3 155821024-155854456 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Cataract, Deafness, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042430 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Vesicles, Cytosol" "HPA042430: AB_10806238" "unprognostic (5.12e-3)" "unprognostic (7.78e-2)" "unprognostic (1.13e-2)" "unprognostic (7.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-2)" "unprognostic (9.57e-2)" "unprognostic (5.65e-2)" "unprognostic (6.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.73e-2)" "unprognostic (5.74e-2)" 8.8 11.0 3.9 4.9 4.8 2.9 8.4 4.6 4.7 12.3 9.2 7.2 6.9 8.8 12.9 8.0 9.5 7.8 7.6 4.6 5.3 10.4 17.2 8.4 5.0 4.4 4.2 8.0 30.9 11.6 5.9 6.6 4.6 8.3 6.4 6.8 11.2 11.0 4.7 6.4 7.7 7.1 5.2 5.8 8.8 5.4 5.2 7.1 18.8 4.8 6.2 6.8 7.9 7.3 18.9 17.7 7.3 8.3 24.4 23.5 12.9 13.1 21.2 19.8 18.7 8.5 22.0 9.9 24.1 13.1 19.8 17.1 14.3 15.2 20.8 16.5 13.3 11.3 6.5 15.8 41.5 13.3 8.9 18.4 26.7 9.7 49.5 20.5 19.8 12.4 8.6 27.8 14.3 14.3 5.0 3.7 6.8 17.7 14.9 5.6 8.1 29.1 9.7 11.8 7.9 5.9 11.1 24.5 21.4 11.3 8.1 11.2 21.4 10.1 4.9 17.9 13.1 33.2 14.4 12.3 14.6 8.8 14.0 12.7 8.4 6.2 8.9 6.3 9.6 5.4 6.0 6.8 10.4 3.5 5.4 5.5 1.7 6.6 6.5 16.1 5.7 5.9 3.9 4.8 4.6 4.7 4.6 5.3 4.4 4.2 4.6 5.2 5.2 7.3 9.0 22.4 25.0 16.0 14.8 8.9 11.7 20.8 18.2 17.5 16.0 9.0 23.8 18.6 21.5 11.0 27.1 18.2 21.1 14.2 5.9 15.3 13.7 11.2 20.3 13.7 12.5 8.4 17.9 15.4 28.3 19.7 20.9 16.6 12.0 12.8 16.4 64.3 19.5 18.5 17.4 18.1 12.2 14.7 15.8 13.2 18.6 15.2 12.4 10.3 19.0 15.4 12.3 11.1 20.8 14.4 5.3 21.4 33.3 19.5 18.9 17.1 23.4 23.0 13.1 16.0 16.0 19.5 9.2 12.2 9.5 37.6 15.3 10.2 13.9 10.9 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC34A3 "FLJ38680, NPTIIc" ENSG00000198569 "Solute carrier family 34 member 3" Q8N130 9 137230757-137236555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 9.7;kidney: 13.6" "Group enriched" "Detected in some" 9 "Proximal enterocytes: 83.7;Proximal tubular cells: 40.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.0;HDLM-2: 2.8;HeLa: 3.3;MCF7: 7.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA023776 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA023776: AB_1857102" "unprognostic (2.69e-1)" "unprognostic (4.16e-1)" "unprognostic (9.08e-3)" "unprognostic (1.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.05e-2)" "unprognostic (9.84e-3)" "unprognostic (2.05e-2)" "unprognostic (2.20e-2)" "unprognostic (5.94e-2)" "unprognostic (1.94e-2)" "unprognostic (9.12e-2)" "unprognostic (5.80e-2)" "unprognostic (2.20e-1)" 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.0 0.5 0.2 0.0 0.1 0.5 0.2 0.0 2.9 0.4 0.5 0.2 0.2 0.2 13.6 0.0 0.3 0.2 1.8 2.0 0.0 0.6 0.0 1.2 0.0 0.5 0.3 0.0 0.2 1.6 0.0 0.1 0.4 9.7 0.0 0.5 0.2 0.4 0.4 0.8 0.0 0.3 0.0 0.0 0.1 0.5 1.1 0.6 1.2 0.7 1.5 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 4.0 0.5 0.1 0.0 0.1 1.8 0.0 0.0 0.1 2.8 0.3 0.1 3.3 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.3 0.6 0.0 7.6 0.0 0.1 0.3 0.7 0.8 0.9 0.5 0.0 0.0 0.6 0.0 1.3 0.4 0.9 0.2 0.6 2.2 0.0 0.3 0.3 0.3 1.5 0.1 0.7 0.3 0.3 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.2 0.2 1.8 2.0 0.5 0.5 0.8 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 83.7 40.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 SLC35A2 "UGALT, UGAT, UGT, UGT1, UGT2, UGTL" ENSG00000102100 "Solute carrier family 35 member A2" P78381 X 48903180-48911958 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036087 Approved Supported "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "HPA036087: AB_10604093" "prognostic unfavorable (3.16e-4)" "unprognostic (3.34e-1)" "unprognostic (4.88e-3)" "unprognostic (1.11e-1)" "unprognostic (8.15e-3)" "unprognostic (4.25e-3)" "prognostic unfavorable (9.64e-5)" "unprognostic (3.47e-1)" "unprognostic (2.50e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-3)" "unprognostic (9.58e-2)" "unprognostic (3.16e-2)" "prognostic favorable (8.23e-4)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" 15.8 20.5 13.7 12.7 14.3 15.9 14.9 14.3 14.8 18.7 19.4 29.3 17.3 13.1 28.4 24.7 32.6 15.2 15.0 14.5 15.8 19.8 31.8 18.2 11.4 14.6 15.0 9.3 30.0 24.7 21.3 19.9 15.4 17.1 28.2 3.1 23.8 14.8 14.0 21.9 18.0 11.7 14.4 14.7 25.0 7.1 15.9 11.8 15.4 7.2 14.7 19.8 15.4 15.9 48.8 55.2 18.8 27.3 36.5 31.6 29.7 49.7 54.1 51.3 59.9 64.0 84.5 18.8 22.2 54.2 64.4 67.0 51.7 40.0 39.7 27.9 34.0 20.5 33.1 49.6 47.8 38.7 40.9 35.7 69.9 48.6 39.8 28.9 30.6 25.9 38.7 29.8 37.6 47.1 20.5 35.0 39.7 55.3 67.7 22.3 35.5 61.1 44.4 39.1 21.8 36.1 52.9 54.5 28.7 35.1 80.8 30.7 28.2 30.3 30.6 55.4 27.5 45.1 32.8 19.6 38.4 34.1 40.3 18.1 22.3 40.0 15.3 23.4 15.8 10.7 12.6 13.9 27.7 9.9 8.3 14.6 24.2 13.8 17.5 27.7 13.1 11.9 13.7 14.3 14.3 14.8 14.5 15.8 14.6 15.0 15.4 14.4 15.9 15.9 16.2 9.6 17.0 3.3 13.1 14.1 11.7 29.0 2.8 4.5 26.5 10.9 5.2 10.0 23.5 16.5 0.0 31.0 15.6 24.1 3.9 27.4 3.3 24.2 12.0 13.5 12.7 19.0 2.6 32.3 30.6 14.0 18.8 16.8 2.5 8.0 11.0 15.6 23.4 6.7 2.5 31.5 28.5 10.1 14.5 1.3 9.9 12.3 10.6 4.7 21.9 9.4 8.2 4.5 4.4 27.1 19.7 10.9 19.3 18.7 17.8 10.5 50.5 5.7 6.6 9.7 19.4 10.3 6.8 10.9 17.5 48.0 13.8 12.2 21.7 23.4 SLC35A5 FLJ20730 ENSG00000138459 "Solute carrier family 35 member A5" Q9BS91 3 112561709-112585579 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035519, HPA057964" Uncertain Approved "Golgi apparatus" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA035519: AB_10601487, HPA057964: AB_2683566" "unprognostic (7.89e-2)" "unprognostic (2.33e-1)" "unprognostic (7.17e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.45e-1)" "unprognostic (4.78e-2)" "unprognostic (8.60e-3)" "unprognostic (2.60e-1)" "unprognostic (8.21e-2)" "unprognostic (3.51e-1)" "prognostic favorable (4.10e-5)" "unprognostic (2.26e-1)" "unprognostic (1.97e-1)" "unprognostic (8.05e-2)" "unprognostic (3.42e-1)" 15.5 19.3 18.2 13.4 23.9 5.7 14.8 22.4 26.9 15.5 18.4 15.6 16.7 15.6 16.0 14.3 14.6 15.4 9.7 18.1 21.4 20.2 21.0 14.7 15.7 24.0 21.7 17.9 9.5 17.2 9.1 18.4 24.3 16.0 16.1 21.7 11.4 13.9 6.1 9.2 18.3 15.9 23.2 14.2 14.5 18.8 21.2 12.7 26.1 10.2 15.3 12.6 8.3 30.0 20.4 18.4 31.2 18.8 39.3 37.4 18.0 33.2 23.7 27.5 31.5 13.6 22.8 18.1 27.4 28.8 31.3 25.3 22.4 15.6 34.6 14.2 11.1 23.2 15.9 11.4 33.6 20.7 21.5 31.8 30.9 24.3 14.9 34.8 25.1 13.8 13.5 22.1 38.7 7.2 16.2 13.1 20.8 24.0 19.2 14.4 11.4 19.7 34.2 14.9 18.3 24.1 21.3 10.4 38.0 20.9 14.2 13.9 28.3 40.3 21.8 8.6 15.7 15.7 24.4 32.2 29.9 17.2 30.8 14.8 16.4 21.0 10.9 25.9 10.3 14.7 10.2 8.6 19.7 13.6 13.6 11.2 14.6 7.3 27.4 9.4 11.2 10.8 18.2 23.9 22.4 26.9 18.1 21.4 24.0 21.7 24.3 23.2 21.2 30.0 9.9 3.2 10.1 13.1 12.5 6.4 8.3 9.9 11.4 12.8 8.5 6.5 5.5 7.2 12.6 14.7 0.0 36.1 12.5 16.4 9.8 7.8 156.8 9.2 9.1 12.9 7.7 9.2 15.0 7.7 25.6 14.0 10.7 10.0 14.0 9.0 19.6 13.1 17.9 37.0 15.2 11.8 20.3 23.2 9.2 23.5 17.1 13.0 26.6 5.6 14.0 20.3 9.2 23.1 36.6 8.1 13.1 17.3 14.3 8.5 25.8 14.8 10.4 16.9 26.3 9.6 10.6 14.9 15.7 8.9 6.7 29.8 10.7 14.6 10.0 6.5 SLC35C2 "bA394O2.1, C20orf5, CGI-15, OVCOV1" ENSG00000080189 "Solute carrier family 35 member C2" Q9NQQ7 20 46345980-46364458 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027011 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA027011: AB_2672082" "unprognostic (7.25e-2)" "unprognostic (1.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.27e-2)" "unprognostic (1.06e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (9.31e-2)" "unprognostic (7.15e-2)" "unprognostic (1.18e-2)" "unprognostic (3.88e-1)" 23.2 36.3 23.1 17.2 22.3 27.1 23.2 21.3 25.2 26.4 22.6 23.9 21.3 23.1 17.4 31.8 23.2 18.2 17.2 21.8 20.6 27.7 38.3 22.8 24.0 22.6 23.1 25.5 34.9 14.9 20.3 18.2 22.3 31.2 10.1 11.3 30.3 14.0 18.3 32.7 26.4 10.4 21.2 33.6 27.7 25.0 23.4 14.4 29.2 8.2 13.4 22.4 25.6 22.8 35.9 45.1 17.5 15.0 23.9 23.2 36.3 17.6 33.7 19.7 22.6 60.9 54.6 22.5 63.2 19.9 24.7 49.0 9.3 40.5 6.7 19.6 32.5 20.2 29.5 49.0 46.6 27.6 23.6 33.6 51.0 27.4 29.8 20.8 15.2 23.7 33.3 41.5 14.2 85.0 19.8 40.7 24.3 34.1 36.7 18.9 19.7 45.3 25.8 35.1 28.1 39.6 16.4 87.1 60.9 10.4 56.0 47.8 15.7 53.2 33.7 27.5 32.0 55.6 51.5 25.2 58.0 29.7 23.9 42.7 37.9 48.0 37.5 39.9 35.4 29.7 39.0 38.8 42.4 27.9 44.5 40.3 33.5 33.4 30.8 72.9 41.1 44.1 23.1 22.3 21.3 25.2 21.8 20.6 22.6 23.1 22.3 21.2 23.4 22.8 17.0 16.0 19.1 24.5 27.6 14.4 29.0 35.5 29.0 41.3 32.4 25.4 6.7 21.5 29.2 27.6 41.7 89.5 32.6 26.9 13.7 41.3 5.9 12.8 13.0 18.4 21.0 12.4 13.6 61.8 49.2 24.0 26.0 13.9 14.7 20.3 31.8 27.5 38.7 18.5 13.6 35.1 26.4 22.8 8.2 6.7 19.3 23.6 21.4 14.0 36.4 23.4 34.0 11.1 14.2 35.0 26.9 19.2 28.8 50.0 34.8 18.3 18.7 33.6 19.7 20.1 19.0 16.1 23.6 24.8 16.6 79.2 25.9 24.8 30.2 33.1 SLC35E2B ENSG00000189339 "Solute carrier family 35 member E2B" P0CK96 1 1659529-1692795 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045641, HPA062711" Uncertain Uncertain Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA045641: AB_2679402, HPA062711: AB_2684844" "unprognostic (9.00e-2)" "unprognostic (2.13e-1)" "unprognostic (8.74e-3)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.64e-4)" "unprognostic (1.18e-1)" "unprognostic (4.09e-2)" "unprognostic (5.70e-2)" "unprognostic (5.83e-2)" "unprognostic (2.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.92e-1)" "unprognostic (2.68e-2)" "unprognostic (6.61e-2)" "unprognostic (2.54e-2)" "prognostic favorable (5.15e-4)" 21.0 29.7 38.1 20.9 35.9 17.3 25.8 30.7 38.5 35.3 31.3 30.8 31.9 31.8 34.2 20.8 29.2 19.5 19.4 38.8 27.8 27.8 26.1 22.9 32.4 28.8 29.9 39.0 30.7 20.3 43.1 20.4 29.4 30.2 22.1 42.6 29.1 22.5 29.1 29.5 34.1 30.6 26.2 40.1 28.7 10.9 31.1 34.5 30.8 14.6 28.0 26.0 26.5 33.3 13.0 17.4 58.3 49.8 42.3 40.0 16.9 15.6 35.8 16.9 19.7 12.8 33.6 22.6 24.2 33.7 20.9 16.9 23.0 14.9 16.8 28.4 20.1 30.6 37.2 21.7 31.5 24.6 26.2 35.0 31.2 21.4 30.5 47.3 35.5 40.9 31.1 30.8 19.4 9.2 32.3 29.2 19.0 11.2 18.5 28.3 15.9 29.5 29.1 13.1 50.9 46.8 26.4 31.5 50.8 23.8 38.9 34.8 33.5 29.9 12.6 11.7 8.6 25.0 19.6 35.2 22.8 45.2 16.5 1.8 3.7 2.8 7.0 3.3 7.6 3.9 5.9 8.1 2.4 3.9 6.8 5.9 5.5 4.0 2.4 7.6 6.0 5.0 38.1 35.9 30.7 38.5 38.8 27.8 28.8 29.9 29.4 26.2 31.1 33.3 8.2 12.8 28.3 9.8 19.8 7.4 7.1 14.1 18.8 35.5 12.0 8.6 17.1 34.3 24.6 3.7 77.2 14.1 26.0 28.3 0.0 5.7 1.1 9.1 14.8 16.8 25.4 21.5 12.0 6.1 9.6 18.4 30.5 6.8 23.4 13.9 25.4 22.2 10.5 30.3 12.1 24.3 18.3 31.5 8.2 3.9 30.4 13.8 12.4 9.4 21.8 12.3 29.9 14.6 12.9 6.2 17.8 26.7 28.0 9.3 38.1 3.4 23.4 66.5 6.6 16.8 12.0 8.5 16.1 16.3 9.7 8.8 23.1 10.1 26.4 8.7 SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA034828: AB_2674350, HPA049229: AB_2680682" "unprognostic (1.59e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (8.37e-2)" "unprognostic (3.87e-3)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (4.83e-2)" 9.8 22.8 4.6 6.0 5.9 8.0 14.3 12.0 6.6 9.3 31.5 14.7 13.7 10.3 11.5 11.1 8.0 11.1 11.0 6.1 6.4 18.0 14.6 9.9 9.0 6.7 4.8 12.4 15.1 17.4 5.2 11.1 7.1 11.2 13.6 14.1 9.8 6.9 12.3 20.3 12.9 8.9 5.4 10.1 12.9 7.1 5.2 5.7 23.7 11.2 10.0 8.0 6.3 12.0 9.7 9.6 7.7 4.9 48.6 36.8 14.0 15.9 13.2 7.7 12.9 24.3 18.9 18.5 22.1 21.9 21.3 8.7 12.2 12.5 17.9 5.7 4.9 9.7 9.6 19.7 20.8 12.8 24.0 46.8 17.4 17.9 25.9 22.1 15.2 4.6 7.7 11.2 19.1 8.5 5.6 14.0 3.6 15.0 5.2 6.5 13.1 9.7 52.5 15.8 2.1 6.0 12.9 14.5 11.5 12.8 9.4 12.6 12.7 14.3 6.3 9.2 6.7 9.7 8.7 8.2 16.8 8.9 13.6 2.9 0.7 0.6 0.5 0.8 0.6 0.9 0.5 0.4 0.6 1.2 0.6 0.6 2.1 1.0 1.2 0.9 0.9 0.6 4.6 5.9 12.0 6.6 6.1 6.4 6.7 4.8 7.1 5.4 5.2 12.0 18.9 22.4 19.8 39.5 18.0 25.4 31.1 20.0 31.9 10.3 20.4 9.8 25.4 21.5 30.4 73.5 22.9 46.3 11.6 44.1 11.7 28.7 28.3 32.4 21.9 15.4 14.5 9.9 43.4 28.5 72.0 24.8 28.5 38.6 24.1 14.4 12.5 20.8 28.3 5.0 47.0 25.6 12.2 13.4 17.2 15.6 12.5 14.6 8.8 39.4 15.5 21.0 7.2 65.4 83.2 23.1 29.7 13.9 37.5 35.3 47.9 45.1 26.3 19.6 0.0 14.2 22.7 60.0 20.5 32.7 34.0 66.4 10.8 41.0 24.8 35.1 SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 67.6;skeletal muscle: 80.2;tongue: 29.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 53.0" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.8 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.2 0.1 0.0 67.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 80.2 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 29.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.4 0.2 0.2 1.1 0.4 0.1 0.4 0.1 0.1 0.2 0.1 0.8 0.6 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.9 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 SLC37A3 DKFZp761N0624 ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" 19.2 10.2 10.6 10.6 11.5 12.3 21.5 10.9 14.0 30.2 7.4 26.4 14.1 44.0 23.9 11.4 23.4 19.1 12.8 10.8 11.3 15.8 12.8 16.5 9.1 10.3 9.3 20.7 25.7 35.0 17.1 21.8 10.6 14.7 24.5 11.3 23.3 12.7 7.8 13.5 16.4 31.9 8.9 15.7 18.4 7.4 11.7 11.7 21.3 9.9 10.6 22.1 18.3 11.0 18.0 29.9 30.3 53.3 42.7 46.6 36.2 26.3 30.8 17.9 26.6 23.9 38.1 2.7 32.6 24.0 45.8 14.5 18.5 32.0 27.3 40.6 27.1 3.5 7.8 24.1 35.9 0.2 9.7 36.8 32.3 19.0 22.0 31.2 27.9 15.5 18.2 7.3 27.8 34.3 17.5 1.6 44.9 43.2 18.4 9.5 8.1 8.2 34.5 37.0 29.8 36.7 7.3 29.5 29.7 32.3 15.9 1.7 32.0 20.4 14.8 51.8 27.3 14.0 28.4 6.9 21.6 0.2 47.7 7.6 3.6 3.7 6.5 2.0 3.5 2.3 6.9 5.1 3.0 1.7 7.3 5.5 12.3 5.9 1.3 0.9 8.6 3.6 10.6 11.5 10.9 14.0 10.8 11.3 10.3 9.3 10.6 8.9 11.7 11.0 8.5 9.6 12.4 14.4 6.0 15.2 39.8 11.8 8.6 11.4 12.1 8.6 5.1 10.0 16.1 12.9 10.4 17.5 5.8 21.0 1.9 22.3 1.6 24.9 43.8 11.6 21.6 6.1 37.1 26.9 26.4 30.6 19.9 21.3 8.2 15.0 13.2 7.3 4.0 13.5 29.0 22.2 14.2 5.1 9.7 2.3 20.2 3.3 19.6 13.1 7.4 3.6 11.3 26.7 22.4 28.6 14.7 13.5 4.2 31.4 11.2 5.7 18.4 9.0 6.6 15.1 16.9 4.6 5.9 8.5 12.4 13.1 10.6 5.1 18.1 37.4 SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.8" "Group enriched" "Detected in all" 13 "Early spermatids: 271.8;Late spermatids: 753.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (2.16e-3)" "unprognostic (2.30e-2)" "unprognostic (6.23e-3)" "prognostic favorable (6.87e-4)" "unprognostic (3.49e-1)" "unprognostic (8.08e-3)" "unprognostic (9.76e-3)" "unprognostic (6.34e-3)" "unprognostic (1.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "prognostic favorable (2.87e-4)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.50e-2)" "unprognostic (4.93e-3)" 6.0 11.4 7.5 6.0 7.8 2.6 5.3 6.0 8.9 5.1 6.1 5.1 4.3 5.5 6.2 6.5 4.0 5.6 15.9 7.9 7.4 7.3 13.6 5.4 4.3 7.7 7.6 4.6 4.8 14.1 7.2 7.5 8.1 5.5 5.9 4.7 6.2 4.6 9.4 5.3 5.5 7.4 5.8 10.3 5.4 32.8 9.8 3.6 7.8 8.3 4.6 5.4 4.9 7.0 6.9 10.9 10.8 16.5 22.0 12.9 19.3 16.2 18.7 22.7 15.6 9.9 11.0 4.5 8.9 22.9 17.9 15.9 10.2 11.7 13.3 2.8 9.4 5.1 9.3 16.5 32.9 10.6 14.0 25.9 23.6 16.1 10.3 12.3 23.5 10.4 14.9 6.3 16.7 8.0 4.3 6.3 11.7 7.5 16.0 15.2 11.6 12.1 10.0 15.4 7.9 11.3 25.7 17.0 7.0 14.4 7.6 4.2 18.7 12.3 9.3 21.8 5.0 9.7 6.7 5.2 16.8 6.3 9.3 0.1 6.8 2.0 4.0 6.6 2.2 1.3 2.4 2.9 4.5 2.5 1.9 2.1 0.5 1.8 6.4 1.7 1.8 5.5 7.5 7.8 6.0 8.9 7.9 7.4 7.7 7.6 8.1 5.8 9.8 7.0 3.3 3.2 4.4 7.8 2.0 3.8 4.0 4.4 1.2 9.8 4.7 3.2 12.8 4.3 4.8 11.0 12.5 8.4 5.0 3.7 3.9 14.0 271.8 3.5 6.8 6.2 13.1 2.1 13.3 8.5 9.5 5.1 9.7 6.0 1.3 10.7 8.2 9.3 38.6 16.8 15.5 3.1 12.2 10.1 8.2 753.3 9.6 11.6 8.8 9.4 4.0 7.1 8.2 5.0 7.6 12.8 2.7 8.6 1.8 3.7 4.8 5.9 3.8 7.1 6.6 4.8 5.1 6.9 7.6 4.6 4.3 15.3 2.7 8.6 4.9 3.2 SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 57.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.5;Early spermatids: 262.6;Syncytiotrophoblasts: 619.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043785: AB_10961859, HPA061702: " "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.49e-1)" "unprognostic (8.19e-2)" "unprognostic (8.35e-2)" "unprognostic (7.95e-2)" "unprognostic (5.47e-2)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.87e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-1)" 6.1 4.8 5.4 8.8 7.3 7.1 8.2 8.1 6.3 6.5 4.1 9.4 8.1 6.6 6.6 8.4 5.0 8.3 3.8 4.3 6.6 7.4 16.6 8.0 11.2 6.3 5.9 5.4 12.1 10.7 3.3 57.8 6.6 6.1 9.8 10.0 6.4 6.0 4.4 7.6 6.6 8.5 5.5 8.4 8.1 19.2 6.3 8.8 7.7 3.8 14.5 8.4 4.8 8.9 17.9 17.3 17.1 20.0 22.0 20.4 110.0 16.5 21.3 18.3 30.4 29.5 27.2 31.6 28.6 12.7 32.1 22.5 20.2 18.2 22.8 15.4 18.4 10.8 16.4 18.7 31.1 18.9 10.8 26.3 21.0 20.2 25.7 13.7 20.0 21.3 20.9 18.6 16.5 15.0 23.6 16.4 29.4 7.2 15.6 17.6 28.6 32.2 24.7 14.0 8.1 14.5 17.3 9.3 25.4 24.0 20.1 34.4 29.6 3.6 11.7 26.8 16.6 20.5 47.6 20.8 10.9 17.4 11.4 3.3 9.3 5.5 5.2 8.7 7.5 7.4 4.5 6.1 8.4 4.2 6.2 5.3 2.0 7.7 6.9 8.0 5.9 4.9 5.4 7.3 8.1 6.3 4.3 6.6 6.3 5.9 6.6 5.5 6.3 8.9 7.3 6.4 3.1 21.9 14.2 3.2 4.2 8.5 2.8 6.6 5.7 3.9 2.8 11.5 9.8 9.2 8.4 182.5 10.4 8.9 1.9 8.9 262.6 4.4 9.2 8.1 4.2 8.4 56.2 11.4 71.5 7.2 8.6 7.3 2.5 8.0 10.4 22.1 26.3 1.7 57.3 4.3 8.2 10.0 8.0 82.4 7.5 11.7 5.4 38.4 11.0 5.6 4.1 55.8 103.2 10.9 9.7 4.9 8.4 4.6 4.4 7.2 6.3 7.4 6.6 3.3 7.0 15.8 6.5 8.1 3.4 619.9 8.7 4.0 5.2 4.7 SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Early spermatids: 298.2;Late spermatids: 905.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" 40.9 42.4 28.3 24.2 31.4 8.3 37.5 30.6 36.3 51.1 30.4 53.4 14.0 77.9 8.8 21.8 48.1 20.2 59.5 26.0 27.3 80.4 26.7 61.4 18.2 33.0 29.7 50.9 42.3 27.2 51.3 40.6 30.4 52.7 6.8 11.0 31.3 26.2 31.4 32.4 31.8 26.6 26.8 36.5 41.2 73.4 35.0 12.3 46.8 12.6 8.7 45.6 37.4 28.5 23.3 20.4 23.5 26.7 56.3 78.2 6.8 89.7 66.2 50.4 57.0 8.1 15.7 8.8 22.9 69.6 49.6 38.3 7.1 61.7 13.9 25.7 25.9 4.7 52.7 16.7 84.3 8.1 11.0 65.4 43.4 31.9 26.1 62.9 53.4 16.9 4.5 19.6 54.8 20.7 17.4 11.5 11.0 19.8 28.2 20.6 33.6 8.9 86.1 11.1 19.9 37.0 26.9 49.1 26.2 8.7 32.8 11.7 76.0 76.6 34.6 88.1 42.7 14.9 5.2 4.1 85.2 11.2 57.3 2.1 3.6 3.2 12.4 13.3 8.5 4.1 8.2 8.9 4.6 5.1 7.5 6.4 6.6 7.4 15.3 4.9 4.5 5.9 28.3 31.4 30.6 36.3 26.0 27.3 33.0 29.7 30.4 26.8 35.0 28.5 20.0 9.6 6.4 18.6 6.7 18.2 18.3 23.0 17.1 24.0 11.5 15.6 18.3 15.7 8.0 29.5 12.5 11.1 11.6 3.4 9.8 32.9 298.2 6.5 20.3 20.9 9.6 4.4 9.6 20.7 16.4 37.8 6.6 13.1 5.7 15.4 21.8 6.2 18.9 32.0 11.7 7.9 14.2 5.3 12.2 905.5 32.9 9.3 19.6 4.7 26.6 16.7 11.3 8.0 10.1 35.5 8.3 40.3 8.1 23.5 8.2 8.8 4.5 17.0 46.0 16.1 36.2 12.7 6.4 2.4 4.1 19.6 9.6 36.7 5.7 8.3 SLC39A3 ZIP3 ENSG00000141873 "Solute carrier family 39 member 3" Q9BRY0 19 2732204-2740028 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.3" "Group enriched" "Detected in all" 4 "Early spermatids: 302.1;Late spermatids: 433.3;Spermatocytes: 185.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 409.6" "Low region specificity" "Detected in all" "HPA042139, HPA058526" Uncertain Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA042139: AB_10793875, HPA058526: AB_2683743" "unprognostic (1.81e-1)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "prognostic favorable (9.76e-5)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (9.88e-3)" "unprognostic (1.01e-1)" "unprognostic (6.03e-2)" "unprognostic (3.66e-2)" "unprognostic (4.37e-3)" "unprognostic (4.07e-2)" "unprognostic (1.75e-3)" "unprognostic (9.22e-3)" "unprognostic (6.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.80e-2)" 17.9 27.0 19.0 14.7 22.0 46.3 17.4 18.3 23.6 19.6 14.8 18.4 16.7 25.1 30.5 17.3 23.2 15.3 23.3 23.6 18.5 19.8 32.8 16.3 19.1 20.0 18.0 13.5 20.7 34.7 27.2 12.3 18.7 19.3 14.4 10.2 21.3 17.8 22.9 14.9 16.5 23.0 16.7 22.7 17.4 100.3 20.1 21.8 20.5 24.7 16.1 22.3 14.4 18.6 53.3 44.1 32.5 80.3 66.1 45.0 30.6 38.6 46.5 71.3 72.4 47.8 35.0 32.2 23.6 68.2 56.3 42.9 50.2 52.7 44.3 0.4 37.1 144.4 31.4 48.9 72.1 123.2 209.5 40.6 83.3 53.1 43.3 25.6 36.9 61.8 162.8 147.6 48.6 35.2 61.4 99.0 34.6 48.8 59.4 81.4 20.9 100.7 34.1 42.7 44.1 40.3 33.9 24.4 82.4 20.9 42.4 162.7 22.4 49.5 27.0 75.6 56.4 38.7 66.6 32.6 37.4 409.6 59.7 41.1 36.0 67.9 35.9 35.6 30.1 53.3 30.5 29.2 48.9 53.7 24.5 29.2 16.7 29.7 34.1 83.9 21.2 35.2 19.0 22.0 18.3 23.6 23.6 18.5 20.0 18.0 18.7 16.7 20.1 18.6 18.1 3.2 2.8 2.6 31.6 10.3 16.6 37.1 2.2 19.2 25.5 23.6 7.8 24.3 22.6 7.3 8.4 37.5 16.8 20.2 17.6 50.7 302.1 17.8 16.4 21.8 24.0 57.6 5.0 61.8 56.3 18.4 10.7 13.3 24.8 24.2 21.8 31.0 64.9 48.8 5.9 19.7 32.6 25.7 12.9 433.3 21.5 39.3 24.9 4.7 26.7 33.5 26.8 6.6 5.6 46.9 25.8 27.8 12.9 33.3 23.0 23.6 17.6 22.0 26.3 14.0 23.6 185.8 29.7 10.5 9.8 26.4 14.5 29.4 25.6 17.6 SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 237.4;kidney: 110.0;liver: 171.1;pancreas: 306.8" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 798.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 53 "CACO-2: 39.9;Hep G2: 58.5" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" 0.3 0.1 0.2 5.5 0.2 0.1 0.3 0.5 0.4 0.3 0.2 73.7 237.4 0.4 0.0 0.1 0.3 6.5 0.2 0.1 0.1 110.0 171.1 0.2 0.4 0.2 0.1 0.4 306.8 0.0 0.2 0.1 0.1 0.3 45.9 6.4 0.1 0.3 0.1 0.3 219.0 2.6 0.1 0.3 1.4 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.2 0.3 0.5 0.0 0.0 0.1 0.0 39.9 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.6 0.1 0.2 0.2 58.5 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.8 0.0 0.9 0.1 0.2 0.2 0.3 0.5 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.6 0.1 0.0 0.0 0.9 0.1 0.3 0.2 15.7 0.0 3.7 116.7 0.0 0.0 171.9 19.6 0.3 0.6 0.0 0.1 0.2 25.3 2.7 0.2 20.6 0.0 0.1 0.0 0.0 0.0 0.0 2.2 138.9 0.1 0.0 0.2 112.7 0.0 1.6 1.2 1.4 0.0 1.3 0.0 0.0 0.6 0.6 0.0 0.0 0.1 7.4 192.8 0.0 0.0 0.1 798.4 169.9 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.8 0.0 168.7 0.0 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 128.6;pancreas: 233.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Erythroid cells: 82.9;Exocrine glandular cells: 35.4;Hepatocytes: 138.2" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;NB-4: 74.3;U-937: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" 13.9 10.7 3.6 4.7 4.2 35.7 11.1 2.7 5.0 13.1 2.7 15.7 8.7 12.6 10.3 4.4 13.5 18.2 8.6 3.6 2.8 7.3 128.6 9.9 7.4 3.8 3.2 20.3 233.2 1.8 4.4 6.3 3.5 12.8 9.4 1.3 13.8 6.2 17.1 18.8 9.2 8.7 2.7 8.5 30.4 3.4 3.4 2.1 12.7 9.1 6.6 16.2 9.9 3.9 1.1 1.7 1.8 20.3 25.7 18.8 0.2 10.4 13.8 3.0 7.6 6.5 2.8 59.5 2.7 7.9 3.9 1.0 18.1 1.2 3.7 2.8 4.6 30.9 0.5 62.7 33.7 54.3 7.2 23.8 4.4 5.2 23.2 7.3 13.4 34.7 43.9 10.7 3.8 2.3 0.5 74.3 6.6 27.0 13.6 51.0 9.8 27.2 0.5 0.1 23.5 3.6 1.9 0.3 23.8 0.5 1.6 27.3 5.5 3.1 7.1 26.2 1.7 12.1 4.3 35.3 1.5 70.6 4.2 11.1 6.2 0.7 10.9 2.4 9.2 2.9 4.9 7.7 8.4 1.5 4.9 6.9 0.5 7.5 0.2 1.9 9.5 5.5 3.6 4.2 2.7 5.0 3.6 2.8 3.8 3.2 3.5 2.7 3.4 3.9 4.4 0.0 7.3 1.6 3.3 7.0 1.6 0.0 3.4 5.7 1.8 2.4 6.8 47.1 0.6 0.0 0.0 0.2 3.6 3.1 3.9 3.4 21.5 5.3 6.0 4.7 6.0 82.9 3.5 35.4 0.4 10.9 4.6 13.4 3.8 1.3 15.4 138.2 7.4 0.0 1.4 8.8 0.0 8.1 2.9 14.8 15.5 3.2 5.4 5.6 1.3 0.2 5.2 4.0 0.6 11.1 2.9 7.9 6.2 3.2 0.3 0.1 0.7 0.4 6.6 6.4 7.7 0.7 1.5 0.3 3.7 0.1 6.4 2.9 9.0 0.9 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.1;Extravillous trophoblasts: 257.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 333.2;SK-BR-3: 306.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" 74.7 33.2 69.6 43.9 85.0 65.0 72.7 78.4 67.4 64.6 33.4 58.3 26.7 43.0 36.2 81.6 59.0 55.8 71.4 62.7 69.7 68.7 17.8 98.5 75.3 99.6 76.5 32.3 41.2 48.7 20.5 157.5 87.0 43.8 49.5 29.1 55.5 65.8 141.2 78.3 50.8 43.6 84.3 115.5 112.9 82.5 79.1 48.8 64.9 92.4 77.7 56.3 69.2 97.6 333.2 8.3 70.0 42.1 103.9 63.5 201.1 69.6 169.5 112.3 131.6 75.6 154.9 65.6 91.1 193.9 13.6 254.1 10.7 53.2 71.6 1.7 9.3 42.0 39.3 3.1 115.0 0.6 33.9 69.2 69.8 42.3 37.2 91.0 86.8 30.2 20.2 10.8 172.6 243.6 35.1 32.1 24.9 96.9 29.3 74.1 102.7 2.9 37.1 171.8 6.9 42.0 56.7 306.1 7.7 73.8 123.0 3.2 79.8 50.1 18.4 60.5 18.0 4.0 7.9 64.8 12.5 29.1 57.3 146.3 39.4 227.9 114.1 113.0 90.4 92.1 78.5 87.4 20.7 94.8 83.3 87.1 482.8 79.2 278.3 100.4 95.7 147.4 69.6 85.0 78.4 67.4 62.7 69.7 99.6 76.5 87.0 84.3 79.1 97.6 84.0 54.5 29.1 32.3 53.4 9.7 17.3 17.2 13.1 12.3 45.8 29.1 38.6 28.6 47.7 92.0 14.6 137.8 51.9 49.9 1.9 44.1 171.1 15.8 31.4 52.7 9.6 45.0 14.3 44.3 257.0 22.6 84.6 38.6 20.3 7.1 75.7 1.9 37.0 3.3 15.5 17.7 14.2 38.7 3.9 35.1 38.8 22.8 5.4 15.9 10.2 36.4 88.6 18.6 18.4 41.1 31.9 56.4 18.9 9.8 20.1 3.7 19.0 3.0 59.2 26.3 29.4 3.2 2.9 33.5 8.5 93.4 41.2 6.8 23.4 20.6 SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 49.7;Cone photoreceptor cells: 54.2;Endometrial ciliated cells: 57.6;Glandular and luminal cells: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "HMC-1: 18.3;OE19: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" 3.5 2.5 3.8 3.7 4.8 5.8 2.9 1.2 16.6 7.1 14.7 4.4 2.3 4.3 1.5 3.3 7.1 2.7 6.6 5.1 1.5 10.2 0.9 6.7 2.7 6.6 1.0 3.1 7.9 2.5 14.9 5.0 6.6 6.6 1.6 5.4 7.8 5.3 4.6 5.7 4.1 1.7 0.7 4.8 12.5 13.7 2.2 2.3 5.8 1.4 2.0 3.4 2.8 6.1 4.6 9.8 3.7 5.9 0.3 0.3 16.1 2.5 1.5 2.2 1.7 6.4 12.2 0.9 11.8 1.0 3.1 3.7 2.1 1.2 1.0 7.2 3.3 2.7 3.1 0.0 1.7 1.1 18.3 0.8 1.9 1.6 0.9 0.5 1.5 5.0 5.6 0.7 0.8 11.9 11.0 2.5 4.7 30.8 4.1 3.3 0.2 3.1 8.9 7.9 5.5 4.6 2.7 0.8 4.5 2.6 1.9 7.2 0.8 0.0 2.4 3.8 4.9 3.9 12.7 1.3 2.1 4.3 4.0 1.1 0.1 8.3 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 7.0 0.2 0.1 0.3 0.2 0.1 3.8 4.8 1.2 16.6 5.1 1.5 6.6 1.0 6.6 0.7 2.2 6.1 3.3 9.6 12.7 6.5 3.0 2.7 6.6 3.6 5.2 33.1 6.4 5.8 13.5 15.7 8.9 49.7 54.2 8.7 7.5 14.7 0.0 9.3 12.5 57.6 10.8 3.4 2.4 0.0 29.0 2.7 0.8 2.9 37.2 97.1 1.3 1.8 1.1 0.0 6.7 3.3 21.7 7.7 8.2 2.5 3.3 5.9 2.1 8.6 3.6 7.5 1.8 4.3 5.2 6.6 0.9 7.8 4.5 2.2 5.3 6.0 3.7 3.2 22.3 9.2 0.0 1.5 3.2 5.7 2.6 4.4 2.4 16.3 4.6 4.0 5.1 11.3 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.3;Cardiomyocytes: 10.8;Cytotrophoblasts: 14.3;dendritic cells: 9.6;Extravillous trophoblasts: 14.6;Hofbauer cells: 36.1;Syncytiotrophoblasts: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" 57.1 24.4 32.1 14.4 30.4 38.3 53.4 25.3 40.0 30.3 33.5 38.0 9.7 27.4 5.6 46.5 27.0 14.5 32.4 37.0 26.9 49.0 185.4 37.4 18.1 34.5 31.2 21.6 33.8 11.5 23.8 10.3 31.9 32.2 7.5 7.2 38.9 9.9 83.9 55.5 24.5 8.5 29.1 34.4 25.6 77.0 34.3 12.3 68.4 25.9 8.9 26.3 34.2 29.2 34.8 11.7 11.9 23.0 26.0 16.6 16.0 22.4 15.1 17.6 16.6 15.6 18.5 14.6 8.5 20.4 10.3 34.8 16.2 23.8 4.7 44.3 23.8 18.2 16.7 42.6 30.9 44.2 44.5 18.6 23.2 16.2 6.2 9.0 15.3 15.8 6.9 11.6 9.2 26.6 22.1 47.6 3.9 4.7 31.5 38.7 12.4 24.6 12.0 24.4 34.8 15.7 16.9 21.3 25.6 3.1 12.7 48.0 19.4 26.8 27.2 14.3 17.2 5.8 10.0 18.8 20.5 53.2 12.1 0.3 1.7 2.0 0.6 1.7 0.4 0.8 0.7 0.3 1.9 0.6 0.9 1.1 1.2 1.0 1.6 3.5 0.8 0.8 32.1 30.4 25.3 40.0 37.0 26.9 34.5 31.2 31.9 29.1 34.3 29.2 20.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 14.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 14.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 20.8 2.0 0.0 0.0 0.0 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 SLC6A1 "GABATHG, GABATR, GAT1" ENSG00000157103 "Solute carrier family 6 member 1" P30531 3 10992186-11039247 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.3;liver: 87.3;retina: 37.0" "Group enriched" "Detected in some" 4 "Astrocytes: 221.0;Inhibitory neurons: 332.3;Microglial cells: 108.7;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 107.9" "Group enriched" "Detected in some" 16 "glioma: 16.1;liver cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013341, CAB022293" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022293: , HPA013341: AB_1849509" "unprognostic (1.66e-3)" "unprognostic (1.30e-3)" "unprognostic (4.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.53e-1)" "unprognostic (2.53e-1)" "prognostic favorable (3.20e-4)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (8.26e-2)" "unprognostic (2.90e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (7.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (5.34e-2)" 1.9 0.8 51.5 0.4 56.0 2.2 1.0 45.4 67.1 3.3 0.0 1.1 0.4 1.2 2.9 9.1 1.2 1.2 4.1 35.8 53.6 2.9 87.3 2.0 0.5 39.4 63.5 2.1 0.3 15.9 3.6 0.8 34.8 2.4 0.5 37.0 0.4 4.0 2.7 1.7 0.9 0.5 43.0 0.7 0.5 4.1 71.3 17.6 0.7 0.8 0.4 0.9 2.6 39.4 0.2 0.2 0.5 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.3 0.4 0.3 0.4 0.1 0.1 0.5 0.4 0.6 0.2 0.2 0.0 0.5 0.4 1.6 0.8 0.2 0.6 0.6 0.3 0.0 0.0 0.3 0.1 0.1 0.5 0.3 1.0 0.0 0.3 0.2 0.5 0.2 0.3 0.4 0.3 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.2 0.0 0.3 0.3 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.1 0.3 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 51.5 56.0 45.4 67.1 35.8 53.6 39.4 63.5 34.8 43.0 71.3 39.4 0.3 0.0 0.5 221.0 0.0 0.3 0.0 0.0 6.2 26.6 0.1 0.0 2.1 14.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 2.6 0.0 0.0 3.7 0.0 0.0 1.4 0.0 0.0 2.5 0.2 0.0 25.2 0.0 0.0 332.3 0.0 0.0 0.8 0.0 1.6 5.6 0.2 0.0 108.7 0.0 36.6 0.0 130.2 107.9 0.0 0.0 10.1 0.0 0.0 0.0 0.2 0.0 3.7 13.1 9.4 6.8 3.8 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.1" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 324.9" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 4.6;SuSa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" 0.2 0.3 13.4 0.0 16.5 0.1 0.1 11.0 20.1 0.1 13.9 0.1 2.6 0.1 0.3 0.0 7.1 0.0 2.6 12.2 11.9 153.1 36.8 0.8 0.0 11.6 12.6 0.2 0.0 0.0 3.0 0.0 11.7 0.5 0.0 1.1 0.1 0.1 0.5 0.2 0.6 0.0 12.1 0.3 0.1 3.1 13.8 0.1 6.3 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.5 11.0 20.1 12.2 11.9 11.6 12.6 11.7 12.1 13.8 11.7 0.0 0.0 0.6 1.3 1.9 0.0 0.0 0.4 0.0 0.4 0.1 0.1 1.5 0.0 0.1 18.4 2.1 0.0 0.1 0.0 49.0 0.0 1.4 0.6 0.1 0.2 0.0 5.3 3.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 27.0 0.0 0.0 1.2 0.0 2.0 1.6 0.0 0.6 0.3 1.7 0.0 17.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.5 324.9 0.7 0.7 0.0 0.4 0.1 0.6 0.4 0.0 0.0 0.3 0.9 0.0 0.0 0.0 SLC6A15 "FLJ10316, hv7-3, NTT73, SBAT1, V7-3" ENSG00000072041 "Solute carrier family 6 member 15" Q9H2J7 12 84859491-84913629 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.9;retina: 15.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 42.1;Bipolar cells: 19.7;Excitatory neurons: 63.9;Inhibitory neurons: 57.4;Melanocytes: 32.0;Oligodendrocytes: 46.9" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.2;melanoma: 7.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 93.5;ASC TERT1: 55.4;hTERT-HME1: 135.3;SCLC-21H: 91.7;SK-MEL-30: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008609 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Vesicles "HPA008609: AB_1857190" "unprognostic (1.01e-4)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (6.65e-6)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "unprognostic (7.65e-3)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (7.69e-4)" "unprognostic (2.57e-2)" "unprognostic (3.80e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-3)" 0.6 1.4 8.0 0.2 7.8 0.0 0.4 4.0 12.7 0.9 0.0 0.4 0.1 0.5 0.0 2.8 0.2 0.0 0.0 6.9 12.9 0.2 0.0 0.1 0.0 7.4 21.9 0.3 0.0 0.0 5.5 3.8 16.7 0.2 0.2 15.7 0.8 0.1 0.0 1.4 0.4 0.3 0.2 0.0 0.1 0.4 8.8 0.1 0.3 1.6 0.2 0.2 1.3 5.0 0.0 2.5 10.3 0.0 93.5 55.4 0.1 0.1 21.0 1.5 1.0 0.0 0.0 0.0 0.0 0.2 12.0 1.2 0.0 23.7 0.1 0.0 25.1 0.0 4.1 0.0 33.5 0.0 0.2 31.4 48.2 11.9 135.3 25.3 0.3 0.0 0.0 0.0 25.9 0.0 0.1 0.0 28.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.7 22.6 0.1 31.1 71.0 0.2 0.0 0.0 0.0 12.7 6.5 0.1 0.0 0.0 0.0 0.1 23.1 0.0 27.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.0 7.8 4.0 12.7 6.9 12.9 7.4 21.9 16.7 0.2 8.8 5.0 0.0 0.0 0.0 4.2 0.1 2.7 0.0 3.1 42.1 19.7 0.1 0.1 0.5 0.0 0.0 0.0 6.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 63.9 0.0 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 57.4 0.0 0.0 0.0 0.4 0.6 0.0 0.0 32.0 1.9 0.0 1.1 0.0 4.0 46.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 11.1 0.0 0.5 1.0 0.4 0.5 5.8 0.6 0.3 0.0 0.0 0.0 0.0 SLC6A16 NTT5 ENSG00000063127 "Solute carrier family 6 member 16" Q9GZN6 19 49289638-49325215 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 94.2" "Group enriched" "Detected in many" 8 "Early spermatids: 125.9;Late spermatids: 46.8;Spermatocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 18.2;SuSa: 9.9" "Not detected" "Not detected" HPA076812 Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA076812: AB_2686816" "unprognostic (1.98e-1)" "unprognostic (7.15e-3)" "unprognostic (6.39e-3)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.83e-3)" "unprognostic (7.89e-2)" "unprognostic (7.92e-2)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-3)" "unprognostic (1.63e-1)" "unprognostic (3.23e-2)" "unprognostic (3.31e-1)" "unprognostic (2.10e-1)" "unprognostic (8.93e-2)" "unprognostic (4.18e-2)" 4.5 2.0 2.8 2.9 2.2 4.5 3.2 1.2 2.1 4.6 17.9 3.8 1.2 4.0 2.4 1.7 5.8 2.3 2.5 2.2 1.8 8.5 10.0 4.9 7.3 5.0 4.9 7.0 6.9 0.9 1.6 3.2 4.3 5.0 1.1 5.0 1.5 2.9 1.0 2.2 3.7 1.8 2.9 4.7 3.5 94.2 2.5 2.3 3.2 0.5 5.5 3.6 3.4 2.1 0.0 7.3 18.2 6.5 0.3 2.8 3.3 0.9 1.5 0.6 2.0 0.2 0.6 8.5 1.1 0.8 0.3 0.3 2.0 0.3 2.2 1.3 2.1 0.7 0.7 1.7 1.4 0.6 3.0 2.8 1.1 1.4 1.0 5.2 1.6 1.5 1.7 1.1 2.4 1.6 0.5 0.3 6.4 0.3 0.9 0.3 4.4 1.6 1.0 0.0 0.2 0.4 2.9 0.1 0.6 9.9 2.9 0.3 9.3 1.4 6.7 4.2 0.0 4.0 4.6 7.5 0.1 2.0 0.4 0.2 0.3 2.6 1.6 1.2 1.5 4.5 0.5 1.6 0.4 2.2 1.4 0.9 1.9 1.8 2.1 1.1 0.9 1.3 2.8 2.2 1.2 2.1 2.2 1.8 5.0 4.9 4.3 2.9 2.5 2.1 4.4 0.0 1.1 3.6 5.8 1.5 0.9 0.4 2.2 8.6 1.7 1.7 1.5 2.8 0.1 1.8 2.1 0.0 1.7 0.1 11.7 0.8 125.9 2.3 1.6 3.9 0.0 0.0 4.1 0.6 0.0 1.7 0.0 1.5 1.3 0.3 2.2 5.5 0.9 0.0 8.1 0.1 0.0 1.4 1.8 46.8 3.7 0.8 5.4 12.2 1.2 0.5 5.2 2.5 1.7 0.2 0.0 3.4 1.5 0.5 0.0 0.3 11.3 1.2 0.0 1.7 4.9 153.5 8.3 0.3 1.3 0.0 1.1 1.8 0.1 0.3 SLC6A6 TAUT ENSG00000131389 "Solute carrier family 6 member 6" P31641 3 14402576-14489349 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 68.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 571.3;Rod photoreceptor cells: 547.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 59.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 59.2" "Cell line enhanced" "Detected in many" "HeLa: 66.6;RPTEC TERT1: 111.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015028, HPA016488" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions, Cytosol" "HPA015028: AB_1857200, HPA016488: AB_1857202" "unprognostic (8.25e-2)" "unprognostic (7.29e-3)" "unprognostic (2.63e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (5.75e-8)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.58e-1)" "unprognostic (2.56e-1)" "unprognostic (3.81e-1)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-2)" "unprognostic (9.65e-2)" "unprognostic (1.90e-1)" 10.9 25.6 1.7 8.4 6.9 54.7 8.5 5.0 7.7 11.3 0.0 3.9 0.9 10.4 0.0 6.7 6.7 9.4 24.4 3.5 3.8 12.2 1.5 20.5 7.5 9.6 6.6 28.9 2.3 2.5 7.4 7.9 6.7 4.3 2.4 68.5 17.1 7.2 30.9 18.3 17.1 6.9 1.7 15.6 9.4 3.7 11.0 4.5 9.3 8.7 9.1 8.1 6.1 6.8 4.1 18.4 4.6 10.1 11.6 5.7 15.9 4.3 26.4 8.4 6.2 8.8 5.6 12.6 4.5 10.9 11.7 4.3 4.5 10.1 16.5 3.7 9.7 8.8 66.6 24.2 0.0 3.7 22.3 1.9 2.6 7.8 1.6 7.7 14.5 6.2 10.1 3.5 18.6 8.1 9.4 20.3 6.1 7.1 10.8 6.1 7.3 24.9 111.8 28.5 7.2 4.6 3.1 3.2 0.6 36.8 11.5 4.5 15.3 9.7 3.9 5.2 6.2 3.9 6.0 7.1 19.3 6.6 23.2 5.6 9.2 8.6 2.5 7.3 1.3 4.0 2.7 3.0 2.8 2.1 0.5 0.6 59.2 1.8 9.4 1.4 8.7 4.6 1.7 6.9 5.0 7.7 3.5 3.8 9.6 6.6 6.7 1.7 11.0 6.8 42.7 6.4 21.5 1.3 16.4 49.3 17.1 51.5 43.9 126.1 9.5 6.9 4.2 7.2 52.8 20.2 571.3 3.0 14.5 0.5 0.0 12.0 19.6 82.1 23.0 29.4 14.4 9.4 17.4 8.2 15.8 13.5 29.0 126.9 13.3 2.5 11.7 0.6 27.2 10.1 18.5 3.5 46.8 60.1 59.5 16.6 17.4 58.8 17.8 32.8 110.9 30.8 10.3 3.0 23.9 31.1 12.6 17.3 13.3 17.6 51.3 23.3 69.5 547.8 0.0 11.4 8.3 0.4 1.3 15.7 23.9 5.1 25.5 46.8 3.6 16.8 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLC6A9 GLYT1 ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.4;skin 1: 46.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Distal enterocytes: 17.8;Erythroid cells: 33.1;Ionocytes: 20.3" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.3;hTCEpi: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" 3.9 31.0 21.7 4.9 45.5 10.8 4.6 53.2 24.2 12.1 6.3 11.0 2.3 7.4 1.1 23.1 9.5 4.8 2.1 16.1 31.3 4.3 2.3 11.6 1.1 66.3 43.5 2.9 8.2 2.8 1.7 1.4 63.6 3.9 6.3 17.2 11.5 5.5 1.1 46.6 6.0 9.1 45.6 1.9 7.4 1.1 45.9 1.4 5.3 0.6 4.3 12.3 25.1 72.4 19.7 13.7 7.1 18.0 11.2 3.7 15.6 14.7 41.0 24.3 30.1 4.8 7.5 0.3 1.6 42.9 0.0 62.3 11.0 12.5 5.0 0.1 1.8 17.1 33.9 5.8 50.3 3.8 0.7 11.3 106.6 11.9 28.5 15.3 0.6 12.3 13.0 48.5 1.0 10.4 2.9 0.1 5.4 7.4 19.1 2.2 0.0 22.9 2.3 2.2 4.4 4.2 7.4 35.3 7.0 1.7 9.1 10.3 0.2 2.8 11.0 2.4 8.0 53.1 39.2 4.4 9.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 45.5 53.2 24.2 16.1 31.3 66.3 43.5 63.6 45.6 45.9 72.4 1.5 0.0 2.0 5.9 1.1 7.5 0.9 3.2 8.0 30.7 2.2 0.9 0.7 4.3 2.2 1.8 16.7 0.5 0.5 17.8 0.0 3.7 5.9 4.8 0.4 0.7 0.0 33.1 2.2 8.9 1.0 0.9 1.5 2.7 0.0 0.0 0.0 0.3 0.3 1.7 1.5 2.7 20.3 0.0 1.0 0.8 1.5 0.1 3.6 0.0 1.0 1.2 0.0 3.0 16.4 4.2 3.0 1.5 1.3 2.0 9.1 1.1 12.5 11.1 6.6 0.1 10.0 0.1 0.4 8.9 12.9 0.5 0.3 1.2 2.6 3.2 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 331.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 74.1;Kupffer cells: 90.0;Proximal tubular cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 9.3;eosinophil: 14.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 14.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.8;BEWO: 110.6;K-562: 136.9;NTERA-2: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" 27.6 15.2 1.2 7.0 7.1 1.6 27.7 5.5 7.6 31.3 42.8 12.5 36.3 43.6 4.8 37.5 45.9 18.6 7.9 3.4 6.5 119.3 6.9 15.4 4.5 3.4 3.1 67.5 19.9 331.1 15.8 16.0 5.8 39.2 13.7 13.9 23.8 35.5 49.4 31.6 24.2 20.9 0.0 18.5 63.4 21.2 6.7 4.9 23.7 15.4 9.0 29.9 37.5 1.4 1.6 0.0 52.9 0.1 68.8 8.5 110.6 6.0 26.3 0.3 2.0 60.4 3.6 0.4 0.8 13.9 5.4 11.7 8.5 3.5 0.3 0.0 5.2 0.6 0.3 0.0 25.5 0.2 35.8 54.1 33.2 0.9 0.9 11.6 5.2 5.4 136.9 0.3 1.5 1.2 0.3 0.8 64.0 12.9 47.4 0.1 0.9 12.5 0.7 21.4 8.2 0.3 0.2 12.0 32.3 60.1 42.8 0.6 0.5 2.3 1.8 0.7 0.0 0.3 15.9 0.2 6.9 0.0 0.4 9.3 0.1 14.0 0.0 0.1 1.1 0.1 0.9 0.1 0.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.5 2.3 1.2 7.1 5.5 7.6 3.4 6.5 3.4 3.1 5.8 0.0 6.7 1.4 0.5 16.0 15.0 2.3 1.8 3.1 28.8 6.4 29.0 26.4 31.6 15.2 5.7 0.0 9.0 16.5 0.0 18.7 0.5 8.3 5.9 1.9 2.2 13.6 74.1 2.1 33.0 0.0 24.8 2.4 4.4 15.5 53.5 18.4 5.1 27.3 66.4 1.3 59.2 26.9 53.5 33.7 4.1 90.0 3.3 3.1 9.6 15.3 19.6 15.9 0.5 39.3 0.0 4.0 2.6 3.0 6.5 7.9 1.6 26.4 27.3 144.8 1.0 4.4 0.0 2.8 4.7 1.1 1.3 25.3 3.0 41.3 2.9 3.4 18.5 32.3 SLC8A2 "KIAA1087, NCX2" ENSG00000118160 "Solute carrier family 8 member A2" Q9UPR5 19 47428017-47471893 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 38.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.6;Excitatory neurons: 40.3;Inhibitory neurons: 13.6;Oligodendrocytes: 6.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 3.0;SCLC-21H: 8.9;SH-SY5Y: 4.4;SiHa: 3.9;U-2 OS: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050818, HPA054671" Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA050818: AB_2681248, HPA054671: AB_2682568" "unprognostic (3.75e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (4.32e-2)" "unprognostic (1.34e-1)" "unprognostic (6.00e-3)" "unprognostic (1.38e-1)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (8.95e-2)" "unprognostic (4.77e-2)" "unprognostic (2.04e-2)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (9.40e-2)" "unprognostic (1.53e-1)" "unprognostic (1.63e-2)" 0.3 2.6 16.9 0.1 22.5 0.0 0.1 31.6 34.0 0.8 0.0 5.9 0.2 6.5 0.1 1.1 1.9 0.1 0.1 38.3 7.6 0.0 0.1 0.1 0.0 0.0 0.0 0.1 7.7 0.0 7.8 0.0 0.0 0.8 0.3 3.4 0.2 2.5 0.2 0.1 0.8 3.5 0.0 0.0 1.3 1.5 2.5 0.1 0.1 0.0 0.0 2.0 0.5 13.3 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 8.9 4.4 3.9 0.4 0.3 0.2 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 22.5 31.6 34.0 38.3 7.6 0.0 0.0 0.0 0.0 2.5 13.3 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 14.6 0.6 0.3 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.3 2.1 0.3 0.1 0.2 1.8 0.0 40.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 13.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.4 0.0 5.0 6.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.5 0.4 1.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 SLC8A3 NCX3 ENSG00000100678 "Solute carrier family 8 member A3" P57103 14 70044215-70189070 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 10.8;retina: 9.6;skeletal muscle: 20.6;tongue: 9.4" "Group enriched" "Detected in some" 9 "Bipolar cells: 32.8;Excitatory neurons: 80.5;Inhibitory neurons: 129.4;Oligodendrocyte precursor cells: 107.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.2;LHCN-M2: 7.9;SH-SY5Y: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.65e-1)" "unprognostic (5.53e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (1.69e-1)" "unprognostic (3.46e-3)" "unprognostic (4.74e-2)" "unprognostic (1.64e-1)" "unprognostic (1.45e-3)" "unprognostic (8.53e-2)" "unprognostic (5.86e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" 0.3 1.2 7.1 0.3 6.0 0.3 0.2 1.7 6.6 0.4 0.0 0.3 0.3 0.2 0.2 0.3 0.1 0.4 0.6 5.3 7.7 0.1 0.1 0.6 0.2 6.1 7.6 0.0 0.2 0.7 0.9 0.1 7.1 0.3 0.2 9.6 0.3 0.1 20.6 0.3 0.4 0.3 5.4 0.1 0.3 0.1 10.8 0.2 0.0 9.4 0.2 1.2 0.2 4.7 0.0 0.0 4.2 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 24.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 6.0 1.7 6.6 5.3 7.7 6.1 7.6 7.1 5.4 10.8 4.7 0.0 0.0 0.6 2.9 0.0 0.1 0.0 0.0 0.0 32.8 0.0 0.0 1.4 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 80.5 0.0 0.4 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.1 8.4 129.4 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 4.7 0.0 0.8 0.0 107.1 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 149.8;Inhibitory neurons: 159.5;Microglial cells: 396.3;Oligodendrocyte precursor cells: 272.9;Oligodendrocytes: 431.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.3;ASC TERT1: 24.9;HSkMC: 17.6;Karpas-707: 62.8;RPMI-8226: 30.4;U-266/70: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 280000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058234: AB_2683648" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (7.23e-3)" "unprognostic (1.65e-1)" "unprognostic (3.65e-2)" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.66e-1)" "unprognostic (1.35e-3)" "unprognostic (7.73e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (5.57e-7)" "unprognostic (5.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-2)" 12.8 5.1 9.7 8.8 14.4 2.0 5.3 12.5 11.3 6.9 6.9 7.3 3.0 4.2 3.7 12.8 6.8 9.6 5.4 9.9 16.3 2.3 7.1 5.9 14.7 20.4 13.5 7.9 1.0 3.0 3.4 15.9 19.5 8.8 5.8 1.3 4.5 8.5 2.1 7.7 7.0 8.0 14.4 13.1 5.0 1.8 13.8 15.5 3.5 5.0 13.5 11.4 7.7 18.2 0.5 0.5 0.8 1.0 19.3 24.9 0.3 1.0 6.6 0.5 3.1 0.0 0.2 3.0 0.2 2.9 1.5 0.7 0.9 1.9 0.8 12.8 0.2 1.6 0.4 0.0 2.2 0.8 1.3 17.6 5.2 0.7 0.9 1.1 0.3 2.3 0.0 62.8 4.2 0.0 1.5 0.0 0.2 0.0 0.5 2.6 0.1 30.4 0.0 0.5 0.4 0.0 1.5 0.0 0.0 0.4 0.2 0.6 0.0 2.4 0.6 2.8 1.4 29.1 0.1 0.1 4.3 0.4 1.2 0.2 6.2 0.7 4.7 10.6 4.0 3.3 4.9 7.5 8.4 3.7 2.7 4.0 0.5 4.2 9.0 0.6 9.3 4.8 9.7 14.4 12.5 11.3 9.9 16.3 20.4 13.5 19.5 14.4 13.8 18.2 4.5 0.0 1.1 149.8 13.2 3.7 10.4 8.7 22.8 0.2 0.6 1.3 1.5 0.0 3.4 3.7 2.1 0.5 10.4 0.0 0.0 1.0 4.8 0.8 10.1 4.4 0.0 9.9 25.6 0.2 0.5 26.5 7.1 0.8 0.0 0.7 21.8 0.0 55.4 0.0 159.5 0.0 6.1 30.5 9.9 4.4 9.3 31.0 7.2 396.3 24.3 2.8 13.4 272.9 431.8 0.8 0.1 7.2 10.9 11.1 0.0 0.4 1.6 0.1 0.0 18.0 7.0 0.3 0.4 23.9 5.1 1.1 19.7 3.7 0.1 3.9 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.9;Exocrine glandular cells: 68.5;Inhibitory neurons: 57.2;Pancreatic endocrine cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.8" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.8;T-cells: 6.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.8 6.0 11.2 5.2 11.7 4.6 5.7 10.9 12.8 6.2 3.2 6.2 1.1 6.8 2.3 3.4 5.6 7.6 6.2 12.5 11.1 2.5 38.7 3.6 5.9 11.4 9.1 6.7 2.4 0.3 8.5 3.9 12.7 4.1 2.7 12.8 2.4 5.0 3.0 3.0 3.7 7.7 7.0 3.6 4.9 3.6 10.0 3.6 2.9 3.5 5.6 6.5 4.9 11.2 4.9 2.1 5.2 10.5 26.0 20.7 0.0 22.0 7.8 3.2 3.0 2.5 3.0 29.3 3.7 24.3 5.1 1.4 12.2 9.3 4.8 24.7 7.5 30.2 7.5 21.8 13.5 22.5 8.8 18.7 10.8 7.7 27.3 11.1 15.3 8.3 10.1 22.1 10.7 1.7 15.3 10.8 4.4 0.1 6.4 0.0 6.0 12.2 9.0 2.4 17.5 14.9 10.0 2.3 6.0 1.4 2.6 13.4 17.6 7.5 4.3 11.6 6.9 16.8 14.2 21.7 8.7 17.5 3.0 0.0 0.1 0.0 4.9 0.0 6.4 5.1 5.1 4.1 0.9 3.0 3.1 3.8 0.0 11.8 0.1 1.6 2.4 1.8 11.2 11.7 10.9 12.8 12.5 11.1 11.4 9.1 12.7 7.0 10.0 11.2 13.9 0.0 0.5 15.0 15.6 4.8 3.4 2.0 6.2 9.7 3.1 2.8 2.5 8.6 1.1 0.0 27.1 0.5 6.5 0.2 0.0 14.1 12.1 1.1 8.6 17.8 3.0 17.2 57.9 68.5 2.3 13.2 22.4 0.9 1.3 10.3 6.1 39.5 1.4 8.4 57.2 1.1 4.1 1.3 5.3 6.9 5.6 3.4 10.6 5.6 3.9 0.7 0.0 32.6 17.6 94.7 0.3 5.3 12.0 4.9 0.0 1.4 1.1 2.3 6.6 16.5 11.5 5.8 4.2 5.6 3.8 0.3 7.9 4.8 0.3 1.3 SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 82.0;choroid plexus: 28.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 487.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 16.7;RPMI-8226: 12.0;SuSa: 16.1;U-266/70: 23.1;U-266/84: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" 0.0 0.1 48.9 0.1 65.9 0.1 4.0 43.5 80.2 0.0 28.6 0.1 0.0 0.1 0.2 0.1 0.3 0.2 0.9 41.3 46.4 1.2 11.5 2.8 0.7 54.0 51.9 0.2 2.4 0.2 0.4 1.2 52.6 0.7 0.0 0.6 15.8 0.0 0.4 0.5 0.1 0.0 45.2 0.5 0.3 1.9 48.3 0.6 0.2 0.0 0.4 0.2 0.0 82.0 2.1 0.6 0.8 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 3.8 1.4 0.1 2.1 0.2 0.0 0.3 0.3 0.2 0.5 0.7 0.9 0.0 0.5 1.5 0.0 0.4 0.3 0.0 1.7 0.2 0.2 1.5 0.1 0.4 4.0 1.2 0.0 2.6 0.4 0.1 16.7 2.0 0.2 0.2 0.2 12.0 0.0 2.2 1.9 2.9 0.0 0.2 0.2 16.1 3.2 0.9 0.0 0.1 1.7 0.8 0.4 23.1 9.8 0.2 0.1 0.3 0.0 0.2 0.1 0.1 0.4 0.1 0.6 0.4 0.6 0.4 0.0 0.2 0.6 0.4 1.3 0.3 0.0 0.2 0.5 0.1 48.9 65.9 43.5 80.2 41.3 46.4 54.0 51.9 52.6 45.2 48.3 82.0 0.0 35.3 3.1 5.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 2.8 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.8 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 102.1 0.0 0.1 0.0 2.5 487.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 625.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 63.1;HaCaT: 95.5;HMC-1: 55.3;RPMI-8226: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA066327: AB_2732743" "unprognostic (1.05e-3)" "prognostic favorable (8.61e-4)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.57e-6)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-2)" "unprognostic (1.49e-2)" "unprognostic (2.64e-2)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" 11.7 6.2 19.3 6.8 29.5 9.6 8.6 33.7 23.0 8.4 24.1 4.0 1.8 5.3 3.3 10.6 6.9 6.3 26.4 20.3 20.2 10.6 2.9 13.8 6.3 30.2 29.6 4.2 3.0 15.7 6.7 1.0 27.8 4.3 3.4 1.5 4.7 6.2 5.8 15.7 4.2 5.0 22.5 11.1 4.6 17.9 26.1 2.6 10.6 9.6 6.2 8.6 10.8 39.5 10.1 12.3 13.9 0.2 20.9 12.6 0.2 4.0 3.4 1.6 0.4 0.0 63.1 12.1 5.3 1.3 9.1 95.5 2.7 6.3 0.2 8.8 0.4 27.8 20.9 0.0 0.9 0.6 55.3 5.7 6.7 2.9 7.3 5.4 0.0 3.6 0.0 0.1 0.0 1.8 0.0 5.1 3.7 0.2 1.7 0.0 1.1 44.0 13.4 10.0 2.0 3.3 10.5 0.9 0.1 2.0 0.1 8.5 0.0 3.3 4.7 0.0 10.3 25.5 16.0 11.7 4.2 16.9 6.0 4.3 2.4 6.9 1.4 2.0 1.1 0.2 1.5 1.7 1.6 0.0 0.5 0.6 7.5 0.3 1.7 0.0 2.7 0.6 19.3 29.5 33.7 23.0 20.3 20.2 30.2 29.6 27.8 22.5 26.1 39.5 53.5 48.1 32.0 17.0 4.3 39.0 29.3 14.2 22.8 28.1 3.1 13.0 44.0 24.3 16.4 51.5 4.2 0.0 33.1 6.2 1.9 26.6 105.6 15.8 29.0 26.2 37.8 6.1 89.5 8.7 0.1 22.9 0.5 36.2 22.8 94.9 34.6 0.8 4.6 0.0 149.4 7.2 8.2 24.7 95.2 38.5 5.0 34.0 10.6 56.2 43.6 5.2 25.7 20.6 625.8 8.4 11.1 3.0 17.3 41.5 0.0 0.4 22.1 3.1 39.5 17.4 62.0 69.5 11.9 22.6 60.1 0.0 23.3 0.8 7.9 38.2 SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.2" "Cell type enhanced" "Detected in many" "Adipocytes: 61.8;Extravillous trophoblasts: 239.4;Melanocytes: 60.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 197.2;RPTEC TERT1: 193.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in some" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" 32.4 5.6 26.2 1.8 24.0 1.3 23.4 24.2 35.7 11.1 19.6 9.8 1.2 8.7 0.3 16.7 13.1 1.8 48.6 23.9 25.4 35.8 5.0 57.2 2.4 26.5 24.8 6.5 4.9 3.8 2.9 4.7 28.0 5.9 1.8 21.5 8.5 1.0 18.8 25.6 9.2 0.8 25.7 6.6 13.5 2.1 31.6 1.1 8.6 5.6 3.2 12.0 16.8 24.9 14.8 19.1 0.8 10.8 2.5 2.1 26.5 4.7 16.6 14.1 5.4 32.0 14.9 17.8 44.2 0.5 9.6 22.0 16.4 1.0 5.4 2.1 9.6 21.7 22.1 23.8 0.1 16.6 6.7 0.0 6.5 0.3 6.2 4.2 2.5 10.7 17.1 4.6 0.0 14.8 17.2 63.9 5.4 74.1 197.2 30.6 1.1 26.2 193.9 14.2 17.4 25.1 4.1 4.4 15.7 6.5 1.0 7.5 2.8 0.4 10.5 7.0 27.2 9.2 15.9 11.1 38.1 24.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.9 0.7 0.2 0.1 0.0 0.0 0.0 0.0 1.6 0.2 26.2 24.0 24.2 35.7 23.9 25.4 26.5 24.8 28.0 25.7 31.6 24.9 61.8 3.2 1.3 1.3 13.1 27.3 1.4 19.8 1.2 14.1 1.2 0.8 4.4 1.5 5.9 25.8 31.3 2.1 3.7 7.5 0.0 5.9 0.3 8.7 3.6 40.3 0.0 2.1 7.9 2.5 239.4 4.3 20.9 35.6 0.0 0.0 14.6 0.6 5.5 0.0 6.6 8.4 2.0 9.7 33.5 0.7 0.3 11.9 60.5 3.7 0.0 6.1 0.0 1.5 0.3 11.8 1.9 0.7 19.1 3.5 0.8 9.6 1.3 43.2 0.0 1.9 2.9 0.2 3.0 1.1 16.1 23.5 5.6 0.1 7.5 11.0 SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072651 Uncertain "Cytoplasmic bodies" No No "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytoplasmic bodies" "HPA072651: AB_2686544" "unprognostic (2.09e-2)" "unprognostic (3.45e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (3.20e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.70e-9)" "unprognostic (1.28e-1)" "unprognostic (3.21e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.26e-2)" 25.2 43.2 44.5 22.0 46.5 46.7 23.7 43.6 46.0 25.6 42.1 35.4 27.3 27.5 24.6 37.3 27.1 18.8 58.8 42.0 42.8 43.4 47.5 32.7 25.8 49.9 48.3 25.7 28.3 46.3 39.0 26.5 46.9 35.2 22.0 35.3 26.8 23.8 62.8 36.4 32.3 28.0 44.4 33.8 33.4 27.7 50.3 29.4 29.9 43.3 24.8 31.2 25.9 53.3 53.4 45.8 54.8 40.9 52.2 29.5 79.0 54.0 48.2 80.0 67.7 116.2 67.4 48.1 61.6 64.8 63.7 62.8 97.3 68.3 51.4 54.5 80.9 55.6 45.8 64.2 67.6 58.8 54.5 37.4 66.7 76.9 81.5 41.2 52.1 70.4 77.0 47.1 56.9 54.5 48.3 47.5 110.9 97.0 94.6 77.2 41.8 51.1 52.1 63.4 73.4 61.1 68.5 100.6 61.8 71.9 86.8 124.3 44.0 55.4 61.6 59.1 79.6 71.7 17.9 89.1 48.8 57.8 71.7 1.6 3.7 5.2 3.8 3.9 3.1 2.9 2.9 2.8 2.4 2.5 2.5 2.7 4.1 3.0 4.2 2.4 2.0 3.6 44.5 46.5 43.6 46.0 42.0 42.8 49.9 48.3 46.9 44.4 50.3 53.3 9.1 16.0 13.4 21.9 16.8 14.7 7.8 7.3 17.6 12.8 14.7 9.8 39.5 18.6 9.6 20.2 33.3 17.8 10.4 44.8 7.9 12.3 2.8 14.1 9.1 12.9 22.7 9.9 23.9 14.5 10.7 9.4 35.2 16.1 12.7 18.4 9.7 21.6 12.4 18.5 21.4 20.3 8.2 14.4 8.6 5.5 8.4 11.1 5.4 19.7 13.5 11.2 7.2 12.1 24.2 17.9 24.2 7.2 17.9 14.3 23.7 15.5 12.8 12.6 6.6 9.2 10.5 8.5 7.8 16.9 12.1 17.1 14.0 11.4 23.6 15.4 SMIM7 "C19orf42, MGC2747" ENSG00000214046 "Small integral membrane protein 7" Q9BQ49 19 16630751-16660442 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043127 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "HPA043127: AB_10806378" "unprognostic (6.61e-2)" "unprognostic (1.61e-2)" "unprognostic (1.90e-1)" "unprognostic (3.71e-2)" "unprognostic (2.52e-1)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "unprognostic (1.79e-2)" "unprognostic (6.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-3)" "unprognostic (8.29e-3)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (7.64e-2)" 41.6 39.5 39.6 24.8 41.8 19.9 47.2 41.4 48.5 36.7 39.8 34.1 34.4 32.5 72.9 30.0 36.9 30.5 35.8 37.8 41.3 52.7 66.7 33.5 33.7 42.9 41.1 32.2 47.7 54.1 16.1 34.7 42.2 46.5 42.0 18.6 52.3 39.3 18.7 32.1 25.4 36.4 43.0 26.7 38.2 21.0 41.7 29.3 50.0 21.0 34.0 32.8 17.9 44.2 60.6 52.1 48.7 42.3 74.4 64.4 48.9 50.4 69.4 70.7 68.8 45.2 111.8 44.4 67.7 69.3 50.5 48.0 44.5 69.8 86.7 38.1 34.4 42.4 34.9 48.5 43.3 64.2 46.5 49.3 49.8 51.5 52.9 43.0 68.9 40.3 59.9 53.7 81.6 120.2 42.4 55.1 45.2 121.5 77.4 41.3 32.9 43.4 83.4 66.3 26.0 48.2 37.8 41.0 51.2 26.8 59.9 80.5 41.5 55.4 35.7 130.3 83.2 46.4 72.6 56.0 56.3 75.6 71.2 47.5 73.3 38.3 37.1 65.8 35.3 49.6 38.0 37.0 58.8 44.3 37.0 33.6 31.0 42.8 78.3 79.2 44.9 45.3 39.6 41.8 41.4 48.5 37.8 41.3 42.9 41.1 42.2 43.0 41.7 44.2 63.5 67.3 64.5 29.0 75.5 34.2 62.8 114.3 70.6 70.1 69.0 84.6 38.5 57.2 68.8 57.0 95.9 144.1 68.5 67.6 129.1 85.2 18.4 58.2 60.8 61.5 73.0 54.7 35.3 86.3 105.2 74.9 57.1 51.5 50.1 42.3 66.0 85.7 115.6 63.9 32.1 78.3 77.3 77.2 43.9 21.6 88.9 64.6 48.0 21.5 102.4 101.3 98.9 21.6 44.8 87.6 87.0 83.1 76.5 77.6 85.1 140.0 54.6 121.4 72.3 42.3 64.8 84.0 81.0 74.7 35.8 156.4 54.7 66.7 62.7 57.7 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Early spermatids: 179.4;Late spermatids: 359.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" 6.9 8.8 7.6 8.6 7.4 12.7 10.5 9.6 7.8 12.6 15.1 12.7 13.5 7.1 15.5 24.5 21.4 8.7 6.7 7.7 6.9 12.2 7.6 9.7 13.3 7.6 7.9 8.2 17.7 22.1 11.1 6.0 7.2 13.2 12.6 6.5 15.6 5.8 4.1 21.7 12.3 4.9 7.6 13.3 14.2 53.0 7.0 10.3 13.3 1.7 17.1 10.4 14.3 8.8 13.1 14.8 7.7 12.2 13.2 7.1 25.5 4.3 15.7 10.5 9.8 14.0 10.3 7.1 9.0 9.3 22.1 16.4 7.8 18.7 6.3 9.1 20.5 8.2 15.9 8.7 11.0 9.1 9.4 7.7 21.3 9.3 18.4 11.8 9.8 12.4 16.3 12.2 5.3 18.7 14.8 19.7 2.1 17.3 7.5 10.4 3.6 7.7 19.3 21.8 10.1 8.4 8.2 24.9 19.3 6.2 7.9 17.2 6.3 4.7 6.8 3.8 16.3 8.3 2.3 4.6 9.1 8.6 8.5 6.2 9.0 10.8 6.9 8.6 7.8 14.4 7.8 8.2 11.2 20.4 5.6 5.9 2.5 7.3 7.8 14.3 8.2 6.0 7.6 7.4 9.6 7.8 7.7 6.9 7.6 7.9 7.2 7.6 7.0 8.8 3.9 12.8 7.2 1.6 15.9 9.8 12.9 13.8 8.6 1.3 8.9 6.7 2.1 7.2 11.8 12.9 4.2 10.3 9.1 26.1 1.9 19.2 179.4 28.4 4.0 4.4 8.4 4.2 1.4 19.8 18.5 6.1 25.0 4.3 0.0 3.5 3.6 3.6 9.5 0.0 0.5 27.1 14.2 4.1 11.2 359.7 9.3 7.2 8.8 2.8 9.9 3.7 6.2 0.0 1.7 15.4 27.7 9.1 9.8 15.0 37.5 9.3 67.1 4.9 13.1 3.1 5.8 69.9 10.9 13.8 18.6 17.0 7.6 8.7 17.8 16.9 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SNAP47 "C1orf142, SNAP-47, SVAP1" ENSG00000143740 "Synaptosome associated protein 47" Q5SQN1 1 227728200-227781826 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028167 Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA028167: AB_10603032" "unprognostic (3.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.93e-2)" "unprognostic (7.31e-2)" "unprognostic (4.88e-2)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-2)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (6.14e-2)" "unprognostic (4.81e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" 14.2 43.8 19.8 10.0 22.0 10.1 16.9 18.3 23.8 23.9 12.5 20.5 10.1 28.9 15.3 14.0 25.9 12.4 38.6 22.4 17.0 19.4 27.0 11.7 18.1 14.4 15.4 47.2 16.5 23.5 27.4 20.1 15.2 17.3 8.9 12.9 18.2 12.1 36.3 16.6 15.3 18.5 15.3 14.6 17.0 38.6 16.7 17.1 17.1 23.4 14.1 19.9 14.7 17.7 33.5 44.2 27.2 27.7 30.3 25.1 35.0 21.2 33.7 35.5 26.5 29.4 29.8 23.8 37.9 33.2 27.3 36.2 33.6 37.9 27.6 48.1 63.4 19.8 28.0 18.9 21.6 30.8 17.8 28.0 32.2 43.3 24.7 28.3 29.4 28.7 37.6 23.7 32.1 22.0 31.5 29.0 44.3 42.5 65.1 32.8 32.3 37.7 20.4 28.1 50.5 32.1 33.6 44.0 33.5 26.4 55.1 27.8 21.3 30.9 38.4 30.7 52.5 30.2 23.2 28.9 28.0 23.0 40.8 19.1 21.0 34.0 29.4 21.2 28.3 22.6 33.1 34.2 23.3 21.3 27.1 25.4 7.4 30.5 27.7 24.0 46.4 25.4 19.8 22.0 18.3 23.8 22.4 17.0 14.4 15.4 15.2 15.3 16.7 17.7 10.1 6.4 13.1 9.4 16.1 13.4 15.9 16.2 16.5 30.8 16.5 14.7 13.0 22.8 13.2 14.7 27.1 24.3 18.7 8.7 35.2 19.9 49.4 7.2 14.3 11.7 16.2 13.5 12.0 18.2 28.4 15.1 10.7 6.9 5.7 21.0 11.0 13.8 16.3 42.1 9.6 8.6 22.4 8.8 6.2 95.9 25.7 7.6 12.4 8.4 22.3 30.5 45.3 6.6 6.1 17.0 3.3 20.7 22.7 16.5 12.4 15.8 8.9 33.5 13.1 12.0 14.0 41.9 26.4 8.5 15.3 27.5 19.4 23.3 10.5 10.1 SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85505496-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Cytosol" "HPA017639: AB_1857345" "unprognostic (1.16e-2)" "unprognostic (3.29e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (1.57e-2)" "unprognostic (3.14e-2)" "unprognostic (2.37e-2)" "unprognostic (1.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (4.72e-3)" 27.3 39.9 39.0 23.0 40.5 31.4 41.7 44.4 61.0 30.8 49.7 39.7 29.8 23.5 57.3 24.3 28.2 28.3 24.8 40.7 47.0 54.4 69.6 39.6 32.6 40.1 40.7 26.8 43.6 47.1 36.3 36.2 43.1 33.2 35.1 47.2 27.8 30.8 16.4 28.6 31.7 22.4 40.9 37.4 45.3 87.0 42.5 18.9 40.5 12.9 28.8 35.1 24.7 44.2 46.1 27.3 44.5 64.9 98.3 71.6 46.0 58.0 78.5 44.2 67.5 49.0 75.4 60.3 69.8 74.4 85.9 60.7 30.5 58.8 69.4 53.3 18.0 66.1 36.4 75.1 80.9 62.4 65.0 63.0 43.7 52.0 51.6 81.1 79.4 23.2 67.7 50.4 96.9 52.1 4.4 117.0 18.3 72.1 31.1 26.2 90.6 29.1 107.1 82.7 19.8 44.5 35.0 76.6 56.3 57.9 47.9 108.9 71.6 35.4 21.8 44.1 60.3 50.4 87.0 22.8 71.3 72.2 71.8 36.7 21.5 33.0 19.9 33.6 14.7 13.3 13.4 18.1 26.2 14.7 12.0 15.0 9.9 22.9 40.9 7.9 16.7 15.7 39.0 40.5 44.4 61.0 40.7 47.0 40.1 40.7 43.1 40.9 42.5 44.2 28.5 93.0 47.2 76.4 25.3 14.7 18.7 32.8 15.9 36.4 23.3 15.1 16.9 15.7 39.1 22.0 56.3 50.4 32.6 30.7 5.9 31.7 87.1 37.3 22.2 26.9 31.8 13.2 115.2 41.6 31.9 23.1 37.8 32.5 31.6 36.0 26.0 28.7 35.4 15.2 124.4 26.1 65.1 37.7 22.3 21.6 19.6 33.4 28.4 63.7 43.1 26.1 41.2 85.5 91.0 34.4 22.0 29.3 23.8 15.7 31.9 25.1 58.9 40.7 19.7 26.2 33.0 173.0 14.9 15.9 14.8 56.5 26.4 26.5 28.6 17.7 SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.9;Astrocytes: 50.6;Excitatory neurons: 57.7;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" 7.6 8.0 7.0 7.3 8.4 2.0 9.5 17.3 7.9 6.0 23.9 12.3 3.5 6.9 6.3 7.1 9.7 8.5 8.7 7.5 8.9 11.3 9.1 29.1 11.5 9.6 10.0 7.4 10.0 13.3 10.5 11.8 9.7 14.9 6.7 25.5 6.7 8.6 10.2 6.2 7.9 7.0 8.1 9.5 6.2 12.7 8.8 2.9 16.7 8.6 12.9 7.2 5.4 7.3 11.9 6.2 7.8 11.0 20.5 15.0 11.5 35.6 17.1 17.9 14.9 5.3 8.1 33.6 3.8 26.0 12.4 4.6 8.9 7.8 20.0 55.9 14.5 5.7 7.5 12.8 11.9 3.8 8.0 10.4 8.3 15.6 8.6 36.0 15.7 6.3 12.0 33.3 23.9 3.5 1.5 6.9 6.3 1.6 5.9 4.9 9.0 8.6 43.0 4.5 16.5 11.9 7.4 2.0 30.3 10.8 4.2 4.9 30.0 10.2 6.5 9.8 15.7 29.3 12.8 7.1 16.7 2.8 12.9 0.0 0.0 0.0 0.1 0.0 0.3 0.7 0.3 0.4 0.0 1.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 7.0 8.4 17.3 7.9 7.5 8.9 9.6 10.0 9.7 8.1 8.8 7.3 9.5 25.6 128.9 50.6 12.6 4.8 4.2 2.3 4.6 15.9 7.0 3.4 6.8 0.0 7.3 5.5 31.3 4.8 5.5 5.4 0.0 4.8 5.9 11.5 8.1 9.6 0.0 0.0 57.7 2.6 4.9 4.9 5.1 10.3 1.3 3.9 12.5 8.8 2.0 6.7 60.7 4.0 2.0 3.2 2.5 4.8 9.6 2.2 21.4 32.8 0.6 5.6 3.1 55.3 21.4 3.9 1.6 9.8 11.3 9.4 5.6 2.3 6.7 15.7 0.0 4.8 5.7 9.0 16.2 2.3 6.1 5.6 7.0 10.3 3.3 5.5 SOAT2 ACAT2 ENSG00000167780 "Sterol O-acyltransferase 2" O75908 12 53103486-53124535 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 19.5" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 14.3" "Group enriched" "Detected in some" 8 "liver cancer: 5.2;testis cancer: 5.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "CACO-2: 9.5;Hep G2: 22.6;U-266/70: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.53e-1)" "unprognostic (2.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-4)" "unprognostic (3.88e-3)" "unprognostic (9.26e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (9.05e-2)" "unprognostic (2.37e-1)" "unprognostic (7.58e-3)" "unprognostic (3.28e-1)" 0.3 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.2 11.6 0.4 0.2 0.1 0.6 0.4 0.1 0.0 0.0 0.4 2.9 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.4 0.1 0.0 0.3 19.5 0.0 0.0 2.1 0.2 0.2 0.0 0.1 0.2 0.1 0.2 0.3 0.6 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 9.5 0.1 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.7 0.0 0.0 1.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.4 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.2 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.7 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.5 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.0 0.0 0.2 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 2.5 0.0 0.0 0.0 14.3 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.3 0.0 SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 90.1;testis: 32.0" "Group enriched" "Detected in many" 4 "Early spermatids: 177.9;Late spermatids: 139.8;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 26.0;hTERT-RPE1: 18.4;U-87 MG: 47.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 55: Plasma cells - Humoral immune response" "HPA048393: AB_2680385, HPA061789: AB_2684609" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.09e-5)" "prognostic favorable (9.52e-8)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-2)" "unprognostic (4.49e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "prognostic favorable (6.66e-4)" 3.1 5.3 2.3 3.1 2.9 5.0 2.3 2.0 4.4 3.7 2.8 7.0 6.5 2.2 5.5 2.1 4.6 4.2 3.2 2.0 2.7 5.1 4.8 3.1 3.2 3.7 3.7 8.5 90.1 3.1 8.2 1.4 3.6 3.7 2.6 5.4 7.2 2.2 0.6 0.6 5.9 1.4 2.0 12.3 7.3 32.0 2.2 0.9 2.2 0.1 5.5 6.9 2.5 2.2 3.8 1.6 0.8 2.0 2.0 0.7 10.5 1.4 1.9 1.5 2.2 3.4 8.3 0.3 26.0 2.1 6.0 1.0 0.5 5.2 1.6 4.1 0.5 2.9 3.2 3.7 10.2 2.2 4.7 4.9 1.1 1.6 1.2 18.4 3.1 0.9 0.8 7.0 3.9 8.0 0.8 5.4 0.1 7.2 6.9 0.6 0.7 11.4 2.7 1.6 0.6 3.9 1.8 1.2 3.0 0.3 5.2 0.9 3.3 7.2 1.1 1.6 1.5 13.8 5.7 3.2 47.4 0.8 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.4 0.0 2.3 2.9 2.0 4.4 2.0 2.7 3.7 3.7 3.6 2.0 2.2 2.2 3.2 0.0 0.5 0.3 26.6 0.4 1.0 6.3 1.2 3.2 1.7 1.5 2.3 0.0 7.6 0.0 2.1 2.0 7.6 0.6 0.0 13.2 177.9 7.5 2.3 3.4 4.2 0.4 1.9 7.6 15.9 3.3 5.1 6.0 4.5 0.9 5.7 6.7 1.5 1.7 1.2 1.7 24.4 1.4 2.1 139.8 1.8 2.0 26.6 1.9 2.1 14.7 0.0 0.0 0.3 15.5 1.4 3.0 138.0 1.6 0.3 6.0 19.3 2.5 0.0 1.0 3.6 35.0 4.9 0.4 0.1 20.2 7.2 2.3 0.8 3.9 SPAG9 "CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JIP-4, JIP4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1" ENSG00000008294 "Sperm associated antigen 9" O60271 17 50962174-51120868 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 9.2;neutrophil: 12.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 12.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040446, HPA061458" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Centriolar satellite, Cytosol" "HPA040446: AB_10671691, HPA061458: AB_2684528" "unprognostic (1.36e-1)" "unprognostic (6.61e-2)" "unprognostic (6.04e-3)" "unprognostic (4.65e-2)" "unprognostic (3.52e-2)" "unprognostic (9.73e-2)" "unprognostic (8.13e-2)" "unprognostic (3.72e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.83e-2)" "unprognostic (9.71e-2)" "unprognostic (2.23e-3)" "unprognostic (2.27e-2)" "unprognostic (9.53e-2)" "unprognostic (7.67e-2)" "prognostic unfavorable (8.10e-4)" 32.2 22.6 50.9 19.0 64.6 26.7 22.4 60.7 58.4 21.5 38.2 23.1 20.4 27.6 12.3 29.1 18.7 26.7 22.6 44.2 55.1 33.0 32.9 30.4 13.6 64.0 56.0 30.1 30.6 27.4 17.5 32.0 65.1 17.9 19.7 36.6 14.3 19.3 66.3 22.6 21.0 27.0 58.7 18.4 15.9 51.0 60.1 19.3 40.1 40.6 15.7 29.6 20.0 99.1 53.3 58.5 73.3 36.0 68.0 59.9 64.7 42.6 41.5 46.8 57.9 53.0 35.7 28.6 29.1 70.3 94.1 44.7 48.5 35.8 86.4 43.5 57.7 23.9 46.4 39.5 51.1 34.9 26.8 43.4 40.7 63.3 112.4 44.9 38.9 14.2 53.6 30.9 66.9 26.6 22.0 14.5 19.5 35.5 74.8 24.7 81.8 25.3 42.8 99.4 56.6 78.8 37.6 34.5 38.8 44.0 28.5 40.9 54.6 129.6 30.3 101.0 63.4 43.5 67.4 46.2 44.3 20.4 46.0 9.2 1.2 0.7 1.2 0.8 0.9 1.0 1.0 1.2 1.3 0.9 0.6 0.8 12.1 0.4 0.5 1.0 1.7 0.5 50.9 64.6 60.7 58.4 44.2 55.1 64.0 56.0 65.1 58.7 60.1 99.1 162.5 131.4 121.3 190.3 53.1 165.1 149.7 37.5 107.6 96.0 45.7 38.7 62.6 41.5 41.1 25.8 125.1 43.2 60.2 189.0 27.4 56.7 243.0 151.6 142.1 122.9 69.8 20.4 110.2 57.6 28.4 106.5 81.6 337.1 43.1 52.8 74.3 48.7 36.7 67.3 130.5 56.0 24.4 43.3 246.6 137.8 76.1 123.1 71.2 104.9 49.8 32.7 25.7 192.5 304.7 89.6 123.5 67.0 59.7 156.9 69.6 86.9 39.0 85.5 65.7 109.0 86.4 215.1 54.8 93.8 172.3 138.9 59.4 56.3 56.3 182.5 SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 17.3" "Group enriched" "Detected in some" 73 "Early spermatids: 270.3;Late spermatids: 111.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA017984: AB_1857413" "unprognostic (2.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 270.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 111.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 95.3 154.7 75.1 64.1 76.6 61.3 100.5 80.7 101.1 97.4 88.7 110.1 94.8 101.0 110.8 117.0 92.1 48.4 119.7 75.4 83.9 137.3 172.8 87.8 71.2 82.3 80.5 91.1 231.2 89.5 141.1 59.4 82.1 96.3 84.7 124.6 145.2 79.1 142.2 109.0 103.9 53.0 81.7 105.6 151.1 153.2 81.4 66.6 113.2 49.7 87.1 103.0 94.7 84.9 114.6 102.2 113.4 139.3 164.9 134.4 157.2 157.6 144.5 139.4 128.4 108.1 171.0 114.6 65.7 145.4 142.5 110.2 109.9 142.5 149.1 154.3 115.8 138.6 169.2 164.6 175.1 213.3 229.1 104.7 190.5 148.5 174.4 130.5 117.4 147.5 118.8 418.0 151.8 105.5 168.8 207.2 195.8 317.2 203.9 67.9 95.7 608.6 232.7 148.3 73.6 157.4 148.7 178.1 224.2 102.4 188.1 248.1 106.2 127.3 119.1 226.3 192.1 406.2 654.1 169.8 196.5 209.4 169.8 292.7 129.9 258.2 131.1 137.0 155.1 202.0 158.5 144.2 143.9 149.3 146.8 152.1 100.1 119.6 152.5 620.5 177.1 253.8 75.1 76.6 80.7 101.1 75.4 83.9 82.3 80.5 82.1 81.7 81.4 84.9 172.5 64.1 104.2 23.8 282.3 156.5 227.9 470.7 136.1 465.4 289.0 351.0 148.7 221.6 283.6 310.8 118.9 373.5 488.1 195.2 361.9 353.8 597.8 286.4 180.8 157.6 167.7 143.9 27.1 339.4 399.8 181.9 119.8 181.5 211.6 138.7 131.4 301.8 311.0 102.6 34.4 291.3 325.5 202.9 189.9 1177.6 216.3 192.5 380.6 13.1 321.9 296.9 213.1 21.1 53.2 274.8 274.1 191.8 888.8 295.0 405.5 665.1 374.1 251.3 164.3 152.6 335.5 746.4 504.5 195.8 184.4 351.2 220.8 283.6 267.7 285.3 SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949247-74979033 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 933.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013386 Approved Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA013386: AB_1857426" "unprognostic (2.43e-1)" "unprognostic (7.01e-2)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (9.30e-2)" "unprognostic (2.31e-2)" "unprognostic (7.04e-3)" "unprognostic (9.61e-2)" "unprognostic (8.83e-2)" "unprognostic (2.02e-3)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (5.70e-2)" "unprognostic (1.37e-1)" "unprognostic (8.62e-2)" 81.0 99.4 86.4 104.9 96.6 60.1 108.2 98.7 131.1 127.5 88.8 119.3 90.5 92.2 220.1 72.8 95.9 66.5 76.2 86.3 102.7 105.6 151.6 79.5 98.2 98.5 93.3 84.3 137.3 147.7 75.1 81.2 98.9 106.9 115.1 75.4 139.0 93.3 71.4 56.6 83.3 93.1 99.7 92.5 105.5 50.4 94.3 97.8 143.9 69.5 154.8 95.0 68.1 107.7 141.7 163.4 213.2 192.2 183.2 122.0 115.9 198.6 192.4 179.0 154.8 322.9 311.7 228.2 244.1 168.9 213.6 254.2 187.3 146.1 220.5 190.0 136.4 232.2 189.7 268.9 208.1 249.3 156.7 109.7 186.1 151.5 245.5 156.8 173.7 166.6 271.9 578.0 163.9 215.0 179.1 158.0 131.0 558.3 153.5 219.2 328.2 522.4 208.2 232.3 172.3 172.6 198.1 262.9 687.6 146.7 254.1 187.6 142.0 201.9 124.9 212.1 177.5 245.1 268.8 423.8 83.0 173.4 209.4 546.3 229.2 219.2 279.8 231.0 315.2 400.7 253.7 269.4 222.0 344.3 191.7 229.5 148.5 260.9 209.8 459.5 272.0 428.3 86.4 96.6 98.7 131.1 86.3 102.7 98.5 93.3 98.9 99.7 94.3 107.7 192.3 86.6 143.6 40.5 323.2 304.5 314.0 812.0 129.7 97.6 212.6 199.9 69.1 214.4 406.0 239.1 52.1 330.8 233.5 130.3 189.8 290.0 36.5 126.4 250.4 181.4 125.4 191.5 46.6 288.0 334.4 239.4 104.5 240.2 155.2 114.7 158.1 338.0 278.9 95.9 55.4 255.1 431.3 140.1 283.3 27.2 240.8 159.7 521.2 23.4 188.6 215.6 197.8 48.7 73.5 253.2 140.0 195.6 933.5 355.5 141.7 280.8 231.1 87.3 170.9 153.6 253.6 127.8 133.1 112.1 229.4 464.8 204.6 192.2 189.5 298.1 SPG7 "CAR, CMAR, SPG5C" ENSG00000197912 "SPG7 matrix AAA peptidase subunit, paraplegin" Q9UQ90 16 89490719-89557766 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "unprognostic (1.42e-1)" "unprognostic (1.72e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.22e-4)" "unprognostic (4.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (2.33e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.56e-2)" "unprognostic (7.01e-2)" "unprognostic (1.44e-2)" "unprognostic (2.58e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.25e-4)" 29.8 44.8 19.3 7.0 18.8 8.2 27.9 21.3 28.6 31.5 18.5 33.3 9.9 31.8 4.0 28.2 26.4 6.8 52.3 19.4 18.3 32.4 47.0 24.9 8.9 19.7 18.6 39.0 31.9 13.8 38.7 5.9 20.3 31.2 8.1 9.9 29.0 9.7 56.7 31.3 35.5 9.0 16.9 34.1 31.1 31.9 18.7 10.5 53.1 31.0 8.0 30.1 26.9 20.0 11.5 28.3 17.3 26.6 33.2 24.2 10.9 27.3 24.6 21.0 10.4 23.0 22.3 16.5 32.5 20.1 16.2 30.5 21.5 24.4 14.7 11.7 25.3 11.4 12.0 43.4 16.2 5.5 10.3 15.2 20.1 12.8 14.1 27.9 25.6 22.0 23.1 5.5 21.7 21.0 14.4 22.5 21.9 23.8 21.4 31.8 26.2 10.8 15.9 17.3 16.4 10.5 44.9 8.3 9.5 15.2 22.6 17.0 33.7 13.9 17.2 12.0 12.2 13.7 19.8 12.8 17.7 19.8 17.7 4.5 2.5 3.9 2.7 2.4 2.6 1.6 1.7 1.3 2.8 3.4 3.1 2.0 2.9 3.7 1.7 2.3 1.8 1.0 19.3 18.8 21.3 28.6 19.4 18.3 19.7 18.6 20.3 16.9 18.7 20.0 53.9 48.1 49.4 39.2 45.6 15.9 27.9 30.1 44.9 57.8 31.2 37.2 45.8 22.8 41.5 35.0 95.9 39.9 47.6 42.3 19.6 40.0 66.0 50.5 41.7 49.9 37.2 27.3 58.5 25.8 28.8 35.9 67.2 54.1 21.5 95.3 51.0 38.1 32.2 40.4 53.1 43.8 30.5 34.8 21.8 22.1 42.9 35.2 21.4 35.6 42.6 30.5 51.5 87.0 46.2 39.5 39.5 33.4 43.5 29.5 68.2 23.8 37.7 73.7 6.6 36.9 36.2 57.5 36.5 36.7 18.0 25.9 45.5 68.3 51.0 28.7 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: AB_2685148" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favorable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" 35.6 32.6 24.0 27.3 27.0 23.3 44.1 26.0 34.2 43.1 28.6 42.3 34.7 40.4 41.3 54.3 36.7 34.1 21.5 24.3 26.6 42.8 23.4 33.6 25.7 27.8 27.5 43.8 26.5 48.0 17.3 42.4 28.0 32.9 44.1 19.8 31.3 28.1 14.2 41.3 37.9 31.4 27.9 26.3 37.1 26.5 25.6 25.9 53.0 18.6 34.4 37.2 34.7 31.6 73.0 48.8 46.8 41.6 120.0 92.0 78.4 74.7 94.2 65.3 66.3 31.5 150.7 38.6 45.1 93.9 78.3 198.4 49.7 68.1 73.0 39.8 36.1 36.7 32.7 51.7 80.5 65.5 49.9 82.6 92.6 68.0 74.8 72.3 62.5 43.5 83.8 46.6 91.1 69.6 34.7 47.6 67.5 97.4 57.9 39.4 58.7 33.3 84.1 37.9 35.0 37.2 104.4 81.1 61.3 62.4 39.2 54.2 72.3 58.8 48.0 73.9 56.8 33.2 44.4 23.9 74.2 39.3 79.4 32.4 33.1 20.2 16.7 36.1 17.0 15.4 18.0 17.4 30.6 15.5 21.4 16.6 33.3 18.5 34.2 18.4 25.7 25.5 24.0 27.0 26.0 34.2 24.3 26.6 27.8 27.5 28.0 27.9 25.6 31.6 40.7 38.5 38.3 27.7 22.1 10.6 13.6 14.5 26.2 6.9 33.2 20.6 4.1 4.3 25.9 36.8 14.6 12.7 24.4 8.0 9.8 53.4 94.8 34.7 42.5 23.1 2.4 7.2 35.3 56.4 15.6 32.3 13.7 47.4 24.6 26.9 6.1 4.3 11.0 6.7 32.5 7.2 12.2 5.7 10.3 26.1 6.2 24.6 12.4 20.6 22.0 13.7 7.2 36.7 52.1 60.8 7.1 6.0 26.2 9.8 11.7 28.5 28.0 8.7 13.1 12.1 23.5 35.3 25.9 27.6 9.1 21.8 21.9 33.2 6.9 14.5 SPTSSA "C14orf147, ssSPTa" ENSG00000165389 "Serine palmitoyltransferase small subunit A" Q969W0 14 34432788-34462240 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 405.2;Melanocytes: 435.8;Suprabasal keratinocytes: 443.8;Syncytiotrophoblasts: 512.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 180.0" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (4.00e-1)" "unprognostic (3.19e-2)" "unprognostic (2.44e-2)" "unprognostic (6.64e-2)" "unprognostic (1.19e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (5.86e-2)" 25.1 71.1 13.5 21.1 13.6 5.7 39.3 13.8 17.9 21.0 13.8 38.4 20.8 16.9 25.6 25.3 21.4 27.1 16.2 12.6 15.8 23.5 46.9 33.6 12.2 18.6 15.4 20.1 13.9 18.2 13.3 28.8 17.0 22.5 36.0 15.3 34.2 24.7 24.4 22.2 21.9 27.3 15.1 13.2 20.5 7.1 14.6 8.5 19.8 19.0 13.0 30.6 26.0 16.2 67.4 38.3 37.6 14.0 61.6 42.8 44.4 44.1 27.2 34.1 41.0 31.3 39.4 56.0 38.8 25.1 25.0 28.2 34.1 37.5 53.7 29.7 21.1 35.2 74.0 153.7 48.5 46.5 19.9 39.8 58.9 25.2 40.8 26.4 40.9 15.7 25.6 58.3 30.4 71.0 19.2 47.0 28.9 32.2 47.4 24.8 180.0 41.2 42.8 29.5 24.6 32.6 100.9 87.7 71.3 29.4 39.9 50.0 43.4 26.8 17.5 27.7 33.4 48.1 34.1 41.0 18.0 40.8 30.4 21.5 36.9 4.9 5.4 29.9 5.3 8.3 4.9 5.3 19.6 7.1 5.1 6.2 2.0 20.8 25.5 7.0 5.3 21.5 13.5 13.6 13.8 17.9 12.6 15.8 18.6 15.4 17.0 15.1 14.6 16.2 51.0 144.2 123.5 14.4 33.1 405.2 166.6 192.0 217.9 40.9 165.5 63.1 33.2 70.1 108.9 88.3 10.4 265.8 31.5 189.6 154.6 257.7 1.3 62.2 165.4 65.5 49.7 66.1 11.2 96.8 126.2 100.9 34.7 100.6 32.4 24.1 50.3 79.1 78.3 40.4 13.5 74.9 120.1 67.1 127.6 2.7 45.7 56.5 435.8 15.0 71.0 43.8 18.6 14.1 30.5 71.0 102.4 60.2 70.9 118.3 75.0 96.7 30.8 31.2 46.0 78.5 98.6 1.9 6.1 167.7 443.8 512.4 33.8 82.9 107.6 153.5 SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 79.6" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favorable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" 12.5 12.0 10.4 2.5 11.5 3.7 12.2 11.0 12.4 12.9 9.2 7.3 3.8 6.8 4.2 26.1 5.6 10.3 9.3 10.7 10.1 9.6 14.5 10.5 2.5 11.0 11.2 3.1 20.2 7.0 5.9 4.0 10.8 7.4 4.1 1.5 16.4 2.9 6.3 15.4 7.0 2.6 10.9 6.8 9.7 3.3 10.9 6.0 7.6 5.4 6.0 10.0 14.7 12.7 9.7 4.3 10.3 10.1 29.4 20.4 5.6 10.4 9.3 2.4 5.4 6.5 19.5 21.2 11.7 11.0 11.1 7.0 5.3 7.9 3.9 6.6 17.1 12.3 5.2 15.8 9.2 23.7 6.1 17.6 14.5 5.4 5.3 7.8 14.4 38.5 21.2 47.7 21.1 10.8 36.0 10.3 13.0 53.2 9.3 11.4 3.3 14.0 12.8 7.9 16.0 9.1 10.7 79.6 8.3 9.0 9.4 17.9 8.3 25.0 4.7 2.0 8.1 28.6 15.8 7.9 34.1 29.5 25.9 25.6 35.8 11.7 16.1 56.5 18.6 12.5 12.0 15.2 30.2 12.7 10.2 14.4 1.8 8.6 59.5 61.7 12.5 23.1 10.4 11.5 11.0 12.4 10.7 10.1 11.0 11.2 10.8 10.9 10.9 12.7 25.4 9.6 15.9 4.6 7.8 13.6 13.3 245.5 5.2 4.9 43.8 29.3 5.3 34.3 245.2 5.5 4.2 27.0 21.2 12.2 3.9 93.4 3.2 51.2 31.0 19.6 12.0 14.9 11.1 105.4 106.0 16.2 13.3 105.9 14.0 6.7 17.5 18.6 63.4 10.1 17.1 22.6 57.0 32.4 34.1 0.5 1.8 27.6 24.9 4.7 31.3 21.9 18.6 8.5 23.4 155.5 10.0 5.7 16.8 17.5 9.4 18.4 195.0 3.9 13.1 13.3 28.2 3.5 20.1 32.7 29.7 7.5 7.2 15.4 23.3 108.6 SREBF1 "bHLHd1, SREBP-1c, SREBP1, SREBP1a" ENSG00000072310 "Sterol regulatory element binding transcription factor 1" P36956 17 17810399-17837011 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 219.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "RPMI-8226: 202.5;SK-BR-3: 178.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005406, HPA043343, HPA043878" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB005406: AB_2194226, HPA043343: AB_2678439, HPA043878: AB_2678710" "unprognostic (9.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-2)" "prognostic favorable (2.66e-4)" "unprognostic (4.50e-2)" "unprognostic (1.05e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (3.14e-2)" "unprognostic (9.02e-3)" "prognostic favorable (9.05e-4)" "unprognostic (3.12e-1)" "unprognostic (9.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (7.65e-2)" "unprognostic (2.36e-3)" 42.2 219.2 26.8 7.9 41.5 20.1 46.5 20.4 37.2 51.5 9.4 37.7 28.7 23.4 8.9 68.7 42.7 14.0 27.4 20.0 25.9 24.7 128.5 26.4 9.1 30.1 29.7 41.4 17.0 8.4 37.0 7.8 24.2 37.2 6.7 3.9 89.5 16.7 34.5 47.8 34.0 5.6 23.4 17.2 25.2 35.4 35.8 14.4 27.0 2.9 6.3 32.5 48.8 41.7 54.1 122.5 12.0 85.2 24.9 55.8 23.5 18.5 60.0 16.4 39.2 23.3 104.2 33.5 17.2 14.8 14.5 144.0 16.7 47.2 4.0 21.1 7.2 16.8 86.4 19.1 36.1 2.5 29.6 42.0 19.6 21.8 12.5 12.2 17.6 64.9 36.8 105.8 2.5 118.7 46.9 26.1 17.8 38.3 23.1 32.6 10.8 202.5 9.0 23.1 16.3 70.5 24.4 178.7 48.0 8.9 62.0 32.6 21.5 8.2 40.5 19.5 12.5 32.2 3.1 15.5 48.9 24.6 45.2 0.0 0.3 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.6 1.3 0.1 0.1 0.1 0.0 0.2 26.8 41.5 20.4 37.2 20.0 25.9 30.1 29.7 24.2 23.4 35.8 41.7 6.1 6.4 26.0 66.9 11.9 9.3 12.0 29.2 14.8 24.5 58.0 30.6 9.4 18.6 29.7 20.2 29.2 4.5 11.4 44.5 1.9 16.5 2.7 30.9 37.2 10.5 29.9 24.8 12.8 23.5 15.7 24.7 31.1 31.9 14.7 13.2 12.8 72.2 12.1 58.9 11.3 30.8 24.4 14.0 13.3 4.9 29.8 15.1 8.8 15.0 11.0 51.7 1.0 10.6 56.7 16.7 20.8 10.9 8.4 19.0 33.2 6.6 32.1 31.6 13.1 15.6 12.9 11.4 4.9 40.2 18.3 19.8 13.4 27.5 41.1 25.2 SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" 22.8 80.7 50.1 31.1 58.7 32.3 24.5 22.3 60.5 26.5 2.5 47.1 40.8 34.4 60.5 82.0 27.4 25.3 53.8 51.8 32.3 33.3 36.2 43.2 35.2 38.5 37.8 35.8 45.8 51.4 30.5 24.5 38.3 33.5 31.6 21.0 49.1 22.9 34.1 58.4 35.9 30.1 16.1 26.1 53.8 20.4 37.8 25.0 23.3 33.5 36.2 29.7 39.0 45.1 65.5 45.8 119.4 111.6 68.4 90.9 66.7 21.4 71.1 24.8 50.5 54.3 84.2 115.8 29.7 52.6 91.1 109.6 68.7 141.8 17.5 32.9 75.0 58.0 79.7 54.6 113.8 85.7 37.9 85.8 78.7 65.1 80.6 56.7 49.2 64.2 60.6 135.9 26.4 83.1 62.5 64.5 75.7 81.2 34.9 71.3 68.1 189.0 103.3 67.6 48.2 36.3 49.1 89.3 91.7 69.5 56.3 150.2 53.0 33.2 61.0 15.9 25.8 98.3 54.3 91.7 32.4 64.0 51.9 0.0 4.7 1.6 4.6 3.6 3.1 7.0 2.5 3.3 5.0 4.8 2.2 2.6 0.7 1.4 3.1 6.3 1.5 4.8 50.1 58.7 22.3 60.5 51.8 32.3 38.5 37.8 38.3 16.1 37.8 45.1 14.5 44.8 43.3 100.6 35.4 16.3 13.5 52.2 30.7 41.0 36.3 23.1 30.3 37.1 38.0 58.8 10.4 25.4 23.5 67.0 3.9 20.3 15.9 25.2 10.5 16.8 49.1 14.1 72.6 44.3 22.6 16.3 42.8 59.2 12.7 43.2 8.2 34.3 14.8 57.2 75.1 39.4 52.9 10.3 14.8 7.0 31.4 16.3 7.2 67.5 18.1 18.6 20.6 90.5 129.5 38.4 30.5 27.4 29.2 27.9 26.3 4.8 30.0 18.7 19.7 13.7 20.5 8.4 13.8 55.7 28.1 36.5 19.0 43.0 40.3 30.2 SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 140.8;Leydig cells: 185.8;Peritubular cells: 267.4;Skeletal myocytes: 139.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Group enriched" "Detected in many" 4 "ASC diff: 24.4;hTERT-RPE1: 91.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" 21.3 10.7 18.0 6.4 26.5 0.1 20.1 26.2 15.4 39.5 8.6 21.2 4.4 23.9 17.8 18.3 25.2 21.9 46.0 16.1 30.1 6.1 1.4 8.9 7.0 26.5 29.1 33.8 8.0 3.2 3.8 4.6 27.9 22.4 12.7 2.9 9.4 34.4 60.7 4.4 7.7 24.3 31.5 8.7 7.7 8.3 21.5 8.7 17.1 79.0 12.1 19.2 15.4 38.4 0.8 1.6 4.0 0.0 24.4 14.5 0.2 6.9 10.8 1.1 3.1 0.1 9.5 0.0 1.8 11.0 6.0 3.0 0.0 0.5 2.1 0.1 0.0 0.0 0.1 0.0 2.9 0.1 0.0 9.3 1.0 3.5 0.8 91.6 0.4 0.0 0.0 0.1 8.4 1.9 0.6 1.9 7.9 0.6 2.7 0.3 10.7 3.2 2.4 8.3 0.4 6.3 2.7 0.6 7.0 4.0 0.9 0.3 3.0 2.5 1.8 3.4 1.8 0.3 1.2 0.2 5.3 0.0 8.6 0.0 0.0 2.7 0.0 0.0 0.5 57.4 0.0 0.0 0.1 16.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.7 18.0 26.5 26.2 15.4 16.1 30.1 26.5 29.1 27.9 31.5 21.5 38.4 10.8 3.2 3.2 39.2 30.7 13.6 23.1 21.6 30.1 2.1 21.8 89.2 95.4 10.0 14.8 18.4 0.0 74.0 1.4 36.0 5.9 11.4 4.0 12.4 52.1 10.2 4.9 1.3 3.5 7.1 7.5 140.8 3.6 6.0 0.0 10.7 9.7 0.2 15.3 6.7 5.8 10.1 0.0 0.6 11.1 5.8 185.8 6.6 19.6 18.7 18.6 41.2 0.0 41.7 18.4 2.8 7.3 267.4 41.2 19.4 0.6 3.1 7.9 2.7 39.5 139.9 56.3 0.7 3.8 7.7 7.1 27.8 2.1 30.7 7.7 24.7 SSR3 TRAPG ENSG00000114850 "Signal sequence receptor subunit 3" Q9UNL2 3 156539553-156555149 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 894.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014906 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA014906: AB_2195736" "unprognostic (4.11e-1)" "unprognostic (3.50e-1)" "unprognostic (5.49e-2)" "unprognostic (5.46e-2)" "unprognostic (5.74e-2)" "prognostic unfavorable (3.43e-4)" "prognostic unfavorable (4.46e-7)" "unprognostic (1.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.87e-2)" "unprognostic (2.19e-3)" "unprognostic (6.68e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.23e-2)" "unprognostic (2.92e-2)" "unprognostic (1.39e-2)" "unprognostic (8.29e-2)" 84.9 72.0 36.2 74.2 39.3 52.9 106.2 40.2 44.8 144.4 35.5 84.8 61.7 84.5 173.0 51.8 106.8 59.0 116.0 34.9 44.0 75.3 100.9 60.3 64.0 45.5 39.9 93.8 195.3 72.1 58.7 60.4 46.0 73.9 91.1 29.0 181.2 137.1 61.6 34.2 56.5 113.6 44.9 61.9 82.6 57.9 46.4 48.7 113.9 45.0 87.9 73.5 53.0 51.0 449.0 92.9 113.3 143.4 377.4 354.9 118.1 641.9 363.2 320.6 444.6 184.9 209.1 148.4 277.3 432.9 290.1 203.4 192.5 760.2 762.3 178.7 91.9 264.4 58.5 185.9 402.2 279.9 122.0 318.1 278.3 545.3 1081.7 309.6 400.6 129.0 151.9 528.2 930.8 131.1 96.8 63.1 138.7 253.6 181.5 136.1 185.7 969.9 300.6 105.2 91.2 76.8 166.0 246.3 358.9 176.4 252.3 143.2 508.5 424.0 204.9 325.3 721.8 485.5 207.3 249.0 254.0 231.9 248.1 111.1 88.7 71.6 60.6 104.1 95.7 76.1 64.0 75.4 115.5 46.8 42.6 52.0 30.5 66.7 136.0 162.1 81.1 72.4 36.2 39.3 40.2 44.8 34.9 44.0 45.5 39.9 46.0 44.9 46.4 51.0 103.4 109.0 167.3 22.2 205.3 83.7 132.7 182.6 41.5 33.7 157.8 263.4 153.4 117.2 151.1 73.5 31.3 113.1 142.1 85.1 109.5 238.4 98.1 89.7 281.2 124.9 71.1 91.9 10.7 229.8 470.0 174.0 103.0 160.0 95.7 145.4 123.5 219.0 388.2 25.2 14.3 247.0 69.2 218.1 224.3 38.0 214.9 196.2 145.9 10.3 241.5 89.6 73.2 17.1 18.5 233.2 81.5 223.0 894.2 257.5 90.3 214.7 81.0 37.1 72.3 96.3 178.4 177.1 69.0 74.0 78.7 188.9 109.8 119.5 148.9 157.8 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 8.6 8.3 4.7 6.4 5.8 7.4 7.2 8.4 6.5 9.3 1.6 9.2 3.5 12.5 1.1 2.6 8.2 2.5 10.5 7.1 2.9 8.2 10.3 9.0 6.3 3.1 2.6 7.2 3.6 2.6 6.4 3.2 2.6 7.1 1.6 1.7 3.2 2.8 15.8 4.2 7.1 4.1 1.9 13.2 4.7 6.7 3.3 3.6 6.0 3.1 3.4 8.4 5.6 2.9 1.7 8.6 7.7 11.2 3.9 5.4 2.3 6.1 6.0 6.2 3.0 5.5 4.0 4.6 9.8 6.3 5.8 1.9 3.2 2.5 3.3 9.9 5.0 18.0 4.5 8.7 4.7 6.7 29.4 4.1 1.5 6.7 1.3 8.2 8.6 7.6 25.1 4.2 3.7 1.5 7.5 19.8 10.1 2.9 4.5 13.9 2.9 5.9 5.1 1.5 3.7 9.4 15.8 0.6 7.1 8.1 2.4 7.3 9.9 9.0 10.0 4.0 4.7 8.6 3.9 9.7 10.0 5.9 12.5 4.2 1.9 5.2 2.0 1.8 1.7 2.0 2.3 2.0 1.0 2.9 3.8 3.0 10.1 2.8 1.3 14.3 2.6 1.1 4.7 5.8 8.4 6.5 7.1 2.9 3.1 2.6 2.6 1.9 3.3 2.9 15.4 9.6 5.2 13.4 12.6 3.3 4.2 2.1 2.2 15.7 2.8 3.0 6.8 10.0 1.9 9.2 14.6 4.7 56.1 4.5 0.0 5.7 16.9 1.7 6.5 15.0 13.2 24.8 21.3 4.4 2.5 11.0 2.6 2.2 17.7 19.7 18.2 13.1 13.7 18.5 15.2 4.5 2.0 15.4 35.1 33.2 11.8 11.9 1.8 17.8 24.9 5.6 23.7 16.6 7.4 1.8 1.5 8.2 13.5 3.0 6.8 5.7 1.3 11.1 6.6 8.5 8.8 9.3 8.9 1.1 2.4 1.8 11.5 4.7 5.6 2.3 ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0;tongue: 82.9" "Cell type enhanced" "Detected in many" "Astrocytes: 59.7;Excitatory neurons: 94.4;Granulosa cells: 52.5;Inhibitory neurons: 120.1;Microglial cells: 57.1;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" 12.9 14.7 28.5 5.0 27.3 11.0 11.0 30.8 32.5 14.6 22.8 19.4 2.6 16.7 9.8 8.3 12.8 6.9 26.1 27.2 29.4 9.9 13.5 8.7 6.1 27.9 29.0 14.9 8.0 6.7 17.8 6.5 29.2 13.2 4.4 24.5 8.3 13.3 88.0 7.0 6.6 13.1 23.2 7.6 9.6 22.6 30.8 4.9 8.4 82.9 3.7 16.7 10.1 28.1 4.3 2.7 23.4 11.0 17.4 21.9 3.0 15.5 30.8 14.1 13.7 2.6 6.6 7.0 8.6 19.0 7.7 3.8 2.8 10.2 15.7 8.7 5.8 15.0 10.6 7.5 14.7 6.6 7.1 12.1 7.4 9.7 21.3 26.1 12.1 18.4 8.8 13.1 25.3 2.7 7.0 11.7 9.2 1.0 8.1 11.4 3.3 6.1 11.0 2.4 9.3 13.8 5.5 2.5 14.1 9.6 3.5 30.3 10.4 8.3 3.9 13.3 15.4 10.4 6.1 6.9 11.7 15.7 15.3 1.7 2.1 1.2 3.3 1.1 2.9 2.2 2.1 2.5 1.5 2.8 3.5 2.6 2.4 2.2 1.9 3.3 2.9 3.3 28.5 27.3 30.8 32.5 27.2 29.4 27.9 29.0 29.2 23.2 30.8 28.1 6.7 6.4 19.3 59.7 6.6 3.3 3.0 4.1 5.7 9.4 4.6 3.3 34.5 1.5 3.8 3.7 0.0 3.1 2.7 2.2 5.9 2.6 19.4 2.4 6.6 7.6 2.4 8.4 94.4 2.4 1.6 9.0 1.5 2.8 24.1 52.5 4.6 8.6 3.1 18.5 120.1 1.4 4.1 2.2 3.1 14.5 3.7 4.5 3.6 57.1 3.6 6.1 5.2 66.9 66.2 2.7 0.2 11.7 4.2 2.2 0.1 6.3 4.9 17.8 19.7 5.8 9.8 8.5 5.1 2.7 1.3 1.0 6.0 15.7 1.7 10.0 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST3GAL6 "SIAT10, ST3GALVI" ENSG00000064225 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" Q9Y274 3 98732236-98821201 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 128.8;Hepatocytes: 86.8;Microglial cells: 134.0;Oligodendrocyte precursor cells: 171.4" "Cancer enriched" "Detected in many" 5 "melanoma: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.6;neutrophil: 57.6" "Group enriched" "Detected in many" 143 "dendritic cells: 24.2;granulocytes: 57.6;monocytes: 17.4" "Group enriched" "Detected in many" 4 "RPMI-8226: 96.5;SK-MEL-30: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018792 Approved NA NA 5800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA018792: AB_10964349" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (4.17e-2)" "unprognostic (5.20e-3)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (2.30e-3)" "unprognostic (2.40e-1)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "unprognostic (4.32e-1)" "unprognostic (3.91e-3)" "unprognostic (6.15e-3)" "unprognostic (9.44e-2)" "unprognostic (9.47e-3)" "unprognostic (6.79e-4)" 14.6 7.9 8.2 3.8 8.9 2.4 6.3 14.0 9.9 4.8 3.0 3.8 2.0 2.2 12.0 1.9 6.3 2.2 26.5 9.3 8.5 14.0 56.0 7.8 1.6 19.5 10.1 1.2 3.5 1.1 4.1 8.5 14.3 3.3 2.7 1.5 19.5 2.0 7.9 16.7 1.9 2.0 14.8 3.2 4.5 1.6 9.2 10.6 2.9 6.4 2.8 1.6 1.4 13.1 0.3 1.3 1.8 2.7 3.3 1.1 12.5 0.4 1.5 1.2 2.2 8.7 0.5 6.4 3.3 0.0 4.6 2.1 3.9 2.0 1.1 0.0 2.7 0.2 0.6 15.1 14.0 13.2 23.7 1.5 0.1 3.5 6.6 22.4 14.2 2.6 0.0 6.3 1.3 0.0 2.1 22.6 3.5 0.0 3.5 1.3 1.5 96.5 3.4 0.0 3.8 19.2 5.1 0.5 114.2 3.6 0.4 23.1 10.8 2.9 2.4 0.8 1.3 24.1 2.0 0.0 4.6 18.6 10.3 18.5 17.4 49.6 0.0 9.6 0.0 0.1 0.0 0.0 24.2 0.0 0.2 0.0 57.6 0.1 4.9 5.5 0.0 4.7 8.2 8.9 14.0 9.9 9.3 8.5 19.5 10.1 14.3 14.8 9.2 13.1 10.1 12.8 35.2 2.3 2.3 11.5 2.6 7.0 2.2 1.2 6.4 5.7 40.4 2.8 2.8 3.7 8.4 45.2 0.0 0.0 13.7 6.8 0.3 128.8 4.2 20.2 16.1 6.6 78.5 2.0 69.5 3.8 9.2 41.0 39.1 1.8 32.5 86.8 34.4 0.0 64.2 0.1 30.5 29.5 64.2 1.0 2.8 38.4 65.8 134.0 38.0 0.9 0.0 171.4 51.6 6.2 0.1 6.8 18.0 5.2 0.0 10.0 27.5 3.5 6.6 1.7 2.2 0.1 1.0 2.1 12.8 27.0 2.0 0.3 0.3 1.8 ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 184.1;Early spermatids: 131.4;Excitatory neurons: 191.5;Inhibitory neurons: 176.0;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 115.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA038325: AB_10671740, HPA038326: AB_10672644" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (4.70e-2)" "unprognostic (1.09e-1)" "unprognostic (8.18e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "prognostic favorable (3.39e-5)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" 13.5 21.7 22.6 6.7 22.0 17.8 15.2 50.6 24.7 19.9 11.1 13.6 12.1 14.5 35.8 9.7 18.6 12.3 22.4 21.8 22.6 29.4 41.3 26.1 7.6 15.0 17.4 17.4 32.9 19.0 24.5 20.9 15.9 13.8 12.4 12.6 21.7 21.2 12.5 11.5 11.0 12.6 14.6 10.4 17.3 8.7 22.5 8.6 28.4 11.2 8.6 12.6 11.1 19.7 29.4 17.2 28.2 24.4 31.0 20.5 12.3 23.0 30.2 24.4 35.2 24.0 32.8 7.7 25.5 21.4 34.7 24.6 24.2 24.5 31.3 11.1 33.9 23.4 26.5 20.2 21.8 27.4 39.4 16.1 24.3 30.7 21.8 21.6 24.9 5.2 36.0 54.6 22.3 18.1 0.2 21.0 26.9 40.1 19.3 6.7 18.8 33.6 25.5 16.2 42.2 33.8 27.8 115.5 32.0 20.6 10.1 23.3 19.1 27.6 11.0 30.5 23.3 34.7 28.2 29.6 22.9 24.0 28.6 1.5 3.1 0.4 7.3 1.2 5.1 2.2 4.4 6.2 5.7 1.0 2.9 3.0 0.0 7.0 1.1 5.6 10.3 3.0 22.6 22.0 50.6 24.7 21.8 22.6 15.0 17.4 15.9 14.6 22.5 19.7 6.3 22.4 38.1 184.1 5.0 7.5 8.6 8.8 10.8 12.2 9.0 7.4 13.5 12.8 12.9 5.5 0.0 21.1 6.4 3.1 5.9 6.0 131.4 7.1 5.9 9.5 3.6 15.8 191.5 13.4 22.8 10.6 12.8 14.2 19.6 3.5 8.6 24.5 8.7 3.3 176.0 6.8 8.2 14.4 6.0 53.5 11.1 7.9 7.2 44.0 7.5 12.8 4.1 111.1 46.9 8.8 3.6 6.0 10.3 6.7 3.6 17.3 6.3 1.3 0.0 9.9 12.1 12.8 5.8 7.4 5.5 21.2 4.6 4.6 5.3 8.8 ST8SIA1 "SIAT8, SIAT8A" ENSG00000111728 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" Q92185 12 22063773-22437041 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.2;Inhibitory neurons: 152.0;Oligodendrocyte precursor cells: 198.0" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.5;ASC TERT1: 4.2;hTERT-RPE1: 3.0;RPTEC TERT1: 3.3;SK-MEL-30: 6.2;WM-115: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026775 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA026775: AB_1857534" "unprognostic (1.98e-1)" "unprognostic (5.76e-3)" "unprognostic (1.79e-1)" "unprognostic (9.58e-2)" "unprognostic (2.89e-1)" "unprognostic (6.44e-3)" "unprognostic (1.76e-2)" "unprognostic (1.07e-2)" "unprognostic (3.07e-1)" "unprognostic (1.99e-1)" "unprognostic (6.37e-3)" "unprognostic (2.80e-2)" "unprognostic (1.07e-8)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (5.28e-2)" "unprognostic (3.16e-2)" 1.0 3.5 7.3 2.5 7.0 1.2 2.9 15.0 6.6 2.6 0.0 3.7 0.1 2.3 0.6 1.3 1.3 1.0 2.3 6.3 9.8 0.7 0.2 2.0 4.6 11.6 9.2 1.2 0.5 6.4 0.2 0.1 9.3 3.1 1.6 6.0 1.4 2.0 0.4 2.1 1.3 2.2 8.6 1.3 1.1 0.4 6.8 0.9 0.7 0.4 4.8 4.1 1.8 6.4 0.0 0.3 6.5 0.0 1.0 4.2 0.6 0.0 0.0 0.1 0.3 0.2 0.1 0.8 0.0 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.1 0.6 3.0 0.1 0.0 0.0 0.4 0.2 0.0 0.9 0.2 1.6 2.6 0.0 0.0 0.1 0.1 3.3 0.0 0.0 0.1 0.0 0.1 6.2 0.2 0.5 0.0 0.0 0.5 0.6 0.0 1.0 0.5 0.4 0.5 1.0 0.0 6.5 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.1 7.3 7.0 15.0 6.6 6.3 9.8 11.6 9.2 9.3 8.6 6.8 6.4 0.6 0.0 1.8 43.1 0.4 4.5 0.4 1.4 0.0 9.6 7.2 5.8 4.1 0.0 1.6 0.0 45.9 3.6 1.7 0.1 1.9 0.0 12.8 8.7 2.9 1.3 0.0 3.2 133.2 0.0 13.8 8.3 0.0 0.3 34.1 2.6 1.8 0.0 0.9 5.0 152.0 0.0 0.0 0.0 2.7 5.0 0.3 0.5 12.4 17.8 0.2 46.2 0.0 198.0 4.7 0.0 0.0 0.0 0.7 3.5 0.0 0.5 9.4 4.2 0.0 43.9 2.3 6.3 6.3 0.0 2.4 3.7 5.9 31.3 0.0 0.2 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Respiratory ciliated cells: 38.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 5.6 9.9 1.5 5.4 1.7 2.5 6.6 1.0 3.2 14.1 15.4 9.0 4.4 11.4 13.4 5.1 14.3 10.5 3.5 2.3 1.0 7.3 4.5 7.3 4.5 1.2 2.6 13.4 10.7 9.4 14.8 4.3 0.8 9.6 6.5 11.6 7.3 8.2 3.7 5.0 6.4 8.0 0.3 5.1 8.8 32.0 1.3 3.2 11.8 2.3 4.0 8.2 7.6 1.0 3.7 8.2 17.6 15.0 18.7 14.5 10.9 9.8 7.8 12.2 11.4 10.7 6.0 4.8 13.3 10.3 8.2 7.2 12.2 10.3 10.7 2.8 10.2 4.7 27.1 15.0 9.1 6.7 7.6 15.7 7.5 12.0 8.4 32.3 9.3 6.2 11.1 6.0 10.3 8.5 4.0 8.5 10.7 4.6 5.2 7.3 7.6 5.1 14.9 18.2 14.2 12.3 7.6 12.2 5.0 18.2 12.4 5.3 8.9 16.8 6.1 6.5 6.8 7.5 6.3 2.5 10.4 3.1 7.1 0.0 0.4 0.7 0.3 0.2 0.1 0.4 0.2 0.2 0.3 0.1 0.2 0.3 0.0 0.5 0.3 0.3 0.2 0.4 1.5 1.7 1.0 3.2 2.3 1.0 1.2 2.6 0.8 0.3 1.3 1.0 2.1 9.6 6.3 18.3 1.6 1.1 0.9 3.6 2.8 7.4 7.4 5.5 4.0 5.7 3.7 3.7 37.5 1.8 2.9 2.9 0.0 3.7 16.9 17.5 9.0 3.3 2.4 0.8 22.0 2.5 1.5 4.5 10.7 6.3 1.3 12.2 3.3 5.9 2.7 1.7 18.0 4.4 6.1 2.5 1.2 6.0 5.9 2.0 0.0 2.8 2.5 4.9 1.0 8.5 6.2 2.2 5.0 4.9 0.6 1.6 2.5 4.4 38.2 9.1 6.6 3.1 4.0 28.0 8.9 3.7 1.0 0.8 1.5 11.0 4.9 0.9 STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5" "Cell type enhanced" "Detected in many" "Club cells: 17.6;Endometrial stromal cells: 43.1;Extravillous trophoblasts: 12.1;Fibroblasts: 16.1;Proximal tubular cells: 10.3;Syncytiotrophoblasts: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 33.7;CAPAN-2: 94.5;SH-SY5Y: 59.2;WM-115: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" 0.1 1.0 0.1 0.3 0.0 0.0 0.9 0.0 0.4 24.5 0.4 0.1 0.0 4.3 0.5 1.1 3.6 0.3 0.1 0.1 0.1 4.3 0.0 0.2 0.8 0.1 0.0 0.6 0.1 0.0 5.5 7.6 0.0 5.2 0.0 0.0 0.7 1.4 0.0 0.3 0.2 0.2 0.1 0.1 0.0 3.1 0.3 0.2 0.1 0.1 0.5 1.3 2.4 0.0 0.5 33.7 1.9 0.1 0.0 0.0 6.0 1.0 0.2 0.0 0.0 11.7 94.5 0.0 22.1 0.1 0.7 3.4 1.8 0.0 0.0 0.0 0.2 3.0 1.3 2.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.4 6.1 0.6 2.9 0.1 0.0 0.4 0.0 0.0 0.0 2.9 17.4 59.2 0.0 3.6 0.0 3.6 0.2 0.1 0.0 0.2 7.3 0.6 1.6 0.1 0.2 0.0 0.6 0.0 142.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 9.7 0.0 0.0 0.2 0.3 1.0 0.0 17.6 0.0 0.0 4.2 0.0 0.0 1.9 0.3 1.7 2.1 43.1 1.3 0.0 0.0 0.1 0.0 12.1 16.1 0.0 1.8 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 2.0 0.0 0.8 0.8 6.8 0.4 1.8 1.9 0.1 0.0 0.0 0.0 0.0 4.7 0.0 4.1 0.0 0.4 0.0 10.3 6.6 0.0 0.0 1.3 4.7 0.5 0.5 0.0 0.0 26.4 0.3 0.1 0.0 1.3 STS "ARSC, ARSC1" ENSG00000101846 "Steroid sulfatase" P08842 X 7147237-7804358 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Pregnancy, Steroid metabolism" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 26.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.8;Excitatory neurons: 32.2;Inhibitory neurons: 39.3;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.5;RPMI-8226: 69.8;U-266/70: 110.2;U-698: 47.2" "Low region specificity" "Detected in all" HPA002904 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA002904: AB_1080116" "unprognostic (1.09e-1)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (2.75e-1)" "unprognostic (6.72e-2)" "unprognostic (1.94e-2)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (8.23e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.05e-2)" "unprognostic (2.78e-2)" "unprognostic (2.77e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" 18.2 4.6 3.7 4.5 4.8 2.1 5.8 4.0 12.1 5.6 1.3 6.8 2.8 4.3 2.4 3.1 4.8 7.3 6.6 4.2 3.7 4.8 8.7 8.7 4.1 5.8 6.1 4.7 3.0 2.8 1.2 26.6 5.5 5.2 5.9 6.1 3.1 5.6 5.2 4.9 3.2 6.8 1.3 4.7 12.0 2.4 12.1 4.4 3.9 6.6 3.6 9.4 3.9 7.8 11.5 3.7 7.5 3.0 48.5 24.9 37.5 22.3 7.8 5.8 5.3 19.2 11.2 21.4 5.0 15.5 5.0 3.0 5.4 3.9 5.8 3.3 8.6 1.8 12.7 5.7 2.7 3.8 11.5 8.3 0.7 3.8 2.3 4.0 8.8 2.0 1.4 23.5 15.2 2.9 2.2 3.1 3.3 0.2 4.8 3.9 4.8 69.8 14.2 16.0 5.6 4.8 4.7 8.3 3.0 11.8 3.8 1.6 15.8 22.5 2.2 30.0 4.4 110.2 0.8 47.2 5.9 3.0 6.5 0.9 1.7 0.4 0.4 2.0 0.2 0.4 0.2 0.2 0.9 0.7 0.1 0.3 1.3 0.7 1.3 0.3 0.3 0.6 3.7 4.8 4.0 12.1 4.2 3.7 5.8 6.1 5.5 1.3 12.1 7.8 10.2 12.8 2.2 10.4 1.8 0.9 1.8 2.9 0.6 3.5 3.3 1.5 7.5 1.5 8.5 1.8 0.0 41.8 1.6 16.7 0.0 8.6 0.3 4.5 4.5 4.2 3.6 3.2 32.2 19.9 18.9 6.1 5.1 5.2 7.0 6.7 3.6 8.2 7.7 1.7 39.3 4.6 10.2 7.5 1.7 0.4 2.8 2.8 1.8 10.3 4.7 2.6 0.0 19.1 12.1 10.2 6.5 6.8 1.9 7.8 4.6 3.0 7.5 0.8 0.0 17.5 5.7 0.5 1.7 0.4 1.0 94.0 1.0 4.0 4.3 8.9 STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3 oligosaccharyltransferase complex catalytic subunit A" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 391.8" "Cell type enhanced" "Detected in all" "Plasma cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favorable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" 38.5 39.2 14.6 44.6 17.7 31.8 55.8 17.9 16.9 84.9 29.8 54.0 42.2 60.8 140.4 30.2 56.3 39.5 38.5 15.0 20.1 45.8 69.0 39.0 32.9 19.4 18.4 68.0 69.0 391.8 29.0 63.8 19.6 56.2 59.5 40.0 80.1 77.2 18.4 31.6 42.1 58.9 17.5 34.4 51.4 44.5 17.5 34.8 83.9 24.4 48.8 50.4 33.3 23.1 113.1 99.5 123.7 173.6 230.1 176.4 133.8 198.5 238.5 158.6 196.6 304.2 294.3 143.6 236.2 297.3 222.4 202.7 173.5 176.2 208.5 114.8 90.0 341.0 63.7 215.1 254.4 208.4 153.6 138.4 125.8 219.5 424.5 186.1 182.2 63.9 147.1 210.6 205.4 82.7 84.4 65.6 78.6 221.8 106.0 98.9 107.1 221.5 173.7 170.1 77.5 66.2 142.9 229.3 72.5 144.9 267.8 148.1 164.5 227.7 82.0 97.6 159.7 66.3 82.4 109.6 87.4 206.3 184.7 96.2 46.7 36.6 56.1 45.4 77.9 42.8 53.7 52.0 65.2 32.1 37.1 44.4 15.7 52.8 41.8 158.3 44.0 47.5 14.6 17.7 17.9 16.9 15.0 20.1 19.4 18.4 19.6 17.5 17.5 23.1 17.4 28.9 25.0 6.8 20.8 16.2 14.3 40.3 12.5 11.6 15.2 9.8 23.3 27.1 29.1 16.5 20.9 45.4 21.7 16.1 1.9 30.1 10.6 22.9 51.0 17.3 15.6 19.6 7.6 27.2 73.4 33.0 26.0 57.0 17.1 29.0 32.2 38.5 30.7 1.7 8.9 37.3 20.3 23.6 31.9 5.4 21.5 17.3 24.9 9.4 12.6 13.2 11.3 11.6 10.9 28.6 12.2 18.8 91.9 19.3 15.6 13.6 23.6 15.1 19.7 23.1 32.8 33.5 13.1 21.9 14.8 45.6 14.6 22.3 26.9 13.9 STUM "C1orf95, DKFZp761P211" ENSG00000203685 "Stum, mechanosensory transduction mediator homolog" Q69YW2 1 226548764-226609230 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 234.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.8;Endometrial stromal cells: 3.8;Fibroblasts: 1.5;Glandular and luminal cells: 1.6;Smooth muscle cells: 2.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "medulla oblongata: 234.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HEL: 29.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.3;basal ganglia: 76.6;cerebral cortex: 75.5;hippocampal formation: 74.0;thalamus: 21.3" HPA074381 Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA074381: AB_2732253" "unprognostic (3.23e-3)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (4.09e-2)" "unprognostic (2.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.41e-3)" "unprognostic (3.07e-1)" "unprognostic (5.15e-2)" "unprognostic (7.62e-2)" "unprognostic (3.28e-2)" "prognostic favorable (6.40e-4)" "unprognostic (1.14e-2)" "unprognostic (9.04e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-3)" 3.7 1.0 45.5 1.2 40.0 0.0 2.8 0.0 43.7 3.1 0.0 15.7 1.6 3.2 1.3 5.7 3.1 0.8 2.2 38.8 17.6 5.5 0.1 0.5 0.2 234.8 30.0 2.5 0.9 0.9 7.4 0.4 101.9 4.0 2.1 1.4 1.0 1.2 3.6 4.2 2.7 5.8 9.4 1.0 2.3 1.4 49.5 0.5 0.7 1.3 0.3 6.8 3.5 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 4.9 0.4 29.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.4 0.3 0.0 4.4 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 40.0 0.0 43.7 38.8 17.6 234.8 30.0 101.9 9.4 49.5 5.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 1.0 3.8 0.2 0.0 0.0 0.0 0.2 0.5 1.5 0.0 1.6 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 STX17 FLJ20651 ENSG00000136874 "Syntaxin 17" P56962 9 99906654-99974534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001204 Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Cytosol" "HPA001204: AB_1080118" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (6.71e-2)" "unprognostic (1.88e-1)" "unprognostic (2.36e-1)" "unprognostic (1.70e-2)" "unprognostic (9.75e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.62e-5)" "unprognostic (9.48e-2)" "unprognostic (4.32e-2)" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" 9.3 9.4 7.6 9.3 8.3 11.3 12.3 12.9 8.9 9.5 10.2 9.5 8.9 10.8 10.9 12.0 8.0 8.5 8.1 7.6 7.8 9.7 18.3 9.3 9.2 7.6 7.1 10.9 12.1 11.0 7.6 10.7 7.7 12.4 9.8 10.9 12.8 11.3 16.7 17.6 9.4 10.5 6.7 10.5 10.9 7.9 7.9 11.4 13.2 13.0 10.3 7.7 9.8 10.9 12.9 12.4 11.2 13.0 14.0 13.2 22.3 9.7 13.1 10.1 8.4 14.1 15.8 25.2 9.2 9.5 17.7 14.1 9.6 13.6 7.1 21.3 7.7 16.0 16.3 8.3 15.9 22.5 5.3 12.2 15.9 10.9 15.7 11.7 12.0 21.9 22.4 12.5 8.2 15.4 14.5 8.4 10.0 15.3 8.8 10.8 20.3 10.5 13.7 15.5 6.2 11.9 19.1 13.3 10.2 7.0 13.8 6.9 9.1 6.5 9.9 11.1 8.3 18.5 24.4 4.8 9.2 9.5 6.9 18.6 3.6 7.3 6.4 3.9 9.1 6.3 7.7 7.2 4.6 5.1 8.8 8.4 4.0 14.5 8.2 2.8 4.6 4.6 7.6 8.3 12.9 8.9 7.6 7.8 7.6 7.1 7.7 6.7 7.9 10.9 25.1 16.0 32.6 35.6 26.2 10.6 19.2 13.9 34.7 14.9 20.1 20.6 19.1 14.3 19.4 23.9 20.9 24.7 21.5 10.7 29.4 19.0 67.2 13.5 21.6 18.7 25.2 26.9 41.9 19.4 19.5 18.0 28.1 15.6 26.0 24.0 18.5 25.0 10.4 10.1 40.5 15.7 20.3 12.7 10.6 36.7 25.7 17.1 8.8 45.0 24.8 21.8 24.7 48.7 47.4 15.7 18.1 18.0 24.4 30.9 17.8 21.1 19.6 13.5 39.5 19.6 20.2 33.6 18.1 27.3 12.1 27.4 26.6 27.0 16.2 18.3 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.1;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Excitatory neurons: 20.6;Gastric mucus-secreting cells: 15.3;Paneth cells: 12.6;Proximal enterocytes: 10.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 28.7;HDLM-2: 17.5;HMC-1: 18.3;HUVEC TERT2: 25.5;TIME: 23.8" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.4 0.3 1.2 1.8 3.0 1.1 3.9 0.0 5.2 1.9 0.0 15.9 2.4 0.5 1.2 7.3 2.2 3.5 0.1 3.6 0.0 0.6 0.3 1.3 1.4 0.0 0.0 0.3 0.3 0.0 2.4 0.7 0.0 11.6 17.1 0.9 6.7 0.9 0.1 2.8 11.2 0.6 0.0 0.9 17.5 0.2 0.0 0.2 0.4 0.0 2.5 5.1 3.3 0.3 4.8 0.2 0.0 0.6 0.0 0.0 1.3 7.3 0.7 3.5 3.4 2.6 28.7 0.3 4.7 1.8 4.5 1.4 1.6 8.0 7.4 17.5 0.4 1.0 2.4 0.2 0.0 2.2 18.3 0.4 0.4 5.1 0.3 0.5 25.5 0.2 0.3 0.3 8.1 3.1 0.2 1.3 4.2 11.8 2.0 0.1 2.0 0.3 2.5 14.6 0.9 0.1 4.5 4.9 0.0 6.7 3.5 0.6 23.8 1.0 3.8 0.5 0.8 0.0 1.0 0.2 3.5 0.2 5.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.1 12.5 0.0 0.0 0.0 0.3 1.2 3.0 0.0 5.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.2 0.0 0.0 0.3 0.8 3.1 1.2 0.6 3.3 2.0 0.7 1.5 3.3 0.0 0.0 0.1 1.8 19.6 0.0 0.5 0.2 7.3 0.5 0.4 4.2 0.8 20.6 0.2 0.6 0.2 15.3 4.5 1.3 6.3 0.0 0.0 0.0 0.0 1.6 8.9 2.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 6.2 0.0 0.5 5.9 12.6 0.0 0.9 4.7 10.6 0.0 8.8 0.4 0.0 1.2 0.2 0.2 0.8 3.1 1.0 0.3 1.9 0.0 6.9 5.5 SUN1 "FLJ12407, KIAA0810, UNC84A" ENSG00000164828 "Sad1 and UNC84 domain containing 1" O94901 7 816615-896435 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Meiosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 343.8;Late spermatids: 576.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008346, HPA008461" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane" "HPA008346: AB_1080462, HPA008461: AB_1080461" "unprognostic (2.70e-2)" "unprognostic (1.51e-2)" "unprognostic (1.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.25e-1)" "unprognostic (2.57e-3)" "unprognostic (1.82e-1)" "unprognostic (1.67e-1)" "unprognostic (4.57e-2)" "unprognostic (3.32e-2)" "unprognostic (1.69e-1)" "unprognostic (8.10e-2)" "unprognostic (1.08e-2)" "unprognostic (1.47e-2)" "unprognostic (4.63e-2)" "unprognostic (1.34e-1)" "unprognostic (9.33e-2)" 72.4 26.9 26.1 17.9 25.4 8.3 60.7 43.4 30.7 75.3 29.1 52.3 33.8 73.3 38.5 43.8 66.1 28.2 77.4 25.2 24.3 44.3 28.2 41.7 23.6 23.5 27.2 84.1 34.1 53.0 59.0 47.3 23.1 39.2 30.2 41.4 44.7 34.0 119.2 87.1 42.1 41.5 23.8 38.8 48.1 45.5 24.3 20.0 44.3 99.1 25.1 38.9 57.4 25.3 128.7 34.2 40.2 65.5 43.4 61.6 39.2 31.7 53.4 58.0 59.0 29.1 139.8 30.5 32.2 43.7 113.5 156.8 33.3 55.9 55.9 13.2 33.3 10.0 51.0 27.8 55.3 15.2 24.3 31.0 65.6 46.3 76.4 53.7 42.7 19.0 41.9 22.4 58.6 44.5 10.1 25.2 56.0 44.3 39.0 21.9 22.3 28.7 59.1 40.7 77.2 49.9 40.1 81.4 31.5 64.6 64.6 15.4 32.5 52.8 47.6 55.1 53.2 20.4 25.6 19.0 36.6 12.7 74.4 11.6 9.4 2.5 4.0 8.3 4.2 6.8 7.9 4.6 7.5 5.5 11.0 7.2 0.5 6.6 6.4 1.5 7.3 6.4 26.1 25.4 43.4 30.7 25.2 24.3 23.5 27.2 23.1 23.8 24.3 25.3 107.0 44.8 36.4 63.0 26.5 106.7 96.9 73.2 50.7 72.4 48.0 38.1 103.7 31.5 68.5 40.5 87.6 37.4 14.1 61.9 27.4 41.5 343.8 168.5 40.3 79.9 40.7 31.5 76.5 23.2 23.5 52.6 60.1 143.7 17.1 73.4 62.4 39.1 17.9 112.7 64.5 45.1 59.0 20.0 34.3 576.2 57.2 16.8 42.7 43.1 16.6 24.0 10.3 48.7 49.8 55.8 68.4 42.5 26.4 84.6 37.7 21.9 163.5 67.6 65.7 53.5 73.4 40.9 49.4 36.1 85.7 38.4 22.0 26.1 38.2 137.4 SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38734725-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" 137.8 35.1 123.6 73.6 219.0 160.4 111.7 149.1 155.3 95.4 41.4 107.8 47.6 128.2 22.2 84.0 125.3 41.1 86.7 118.3 133.1 52.8 121.9 107.0 104.0 187.1 182.2 112.9 78.0 18.2 40.3 28.7 170.7 78.2 25.2 12.3 74.9 52.1 145.4 90.3 93.1 46.1 107.2 97.2 94.3 34.6 163.3 74.3 53.1 63.8 60.0 121.7 89.0 257.7 89.8 41.0 40.0 44.7 118.8 29.5 52.0 60.2 69.4 69.7 58.9 36.8 98.7 28.1 71.9 85.9 43.1 65.4 13.4 44.7 28.4 98.0 54.7 18.4 44.7 33.7 71.9 62.3 184.0 25.0 37.3 33.6 31.2 46.9 56.2 55.3 23.5 154.3 38.5 28.7 35.0 53.9 3.9 63.0 26.2 57.6 55.8 85.7 17.4 43.1 35.3 13.2 67.0 73.7 35.1 18.5 49.5 115.3 95.2 50.6 43.3 44.9 79.5 113.1 38.2 30.4 93.8 74.2 86.6 29.0 13.7 18.6 42.3 15.6 27.5 10.8 27.0 34.9 10.7 10.1 27.6 33.6 13.9 24.8 26.9 6.7 19.9 24.8 123.6 219.0 149.1 155.3 118.3 133.1 187.1 182.2 170.7 107.2 163.3 257.7 55.5 22.4 22.9 20.2 57.0 18.1 28.4 15.1 24.5 9.9 36.5 39.0 6.2 40.0 17.8 33.1 8.4 16.9 141.8 65.6 3.9 34.9 1.8 11.6 15.8 37.4 18.6 31.8 12.5 47.6 65.9 34.0 42.8 32.9 25.4 41.5 52.1 109.6 25.0 21.9 7.7 30.1 8.2 42.4 21.4 4.4 61.2 41.8 17.8 16.9 25.5 21.4 201.8 7.1 132.9 60.0 41.8 65.5 44.7 22.0 42.2 18.9 5.7 13.0 52.6 100.7 37.0 3.8 1.1 32.1 17.2 14.8 133.4 10.9 21.4 21.4 SUN5 "dJ726C3.1, SPAG4L, TSARG4" ENSG00000167098 "Sad1 and UNC84 domain containing 5" Q8TC36 20 32983773-33004433 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 449 "testis: 44.8" "Cell type enriched" "Detected in some" 7 "Early spermatids: 510.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048529 Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA048529: AB_2680428" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 510.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 68.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SURF1 ENSG00000148290 "SURF1 cytochrome c oxidase assembly factor" Q15526 9 133351758-133356676 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033946 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "CAB033946: AB_2302648" "unprognostic (1.87e-1)" "unprognostic (7.76e-3)" "unprognostic (1.34e-2)" "unprognostic (4.26e-3)" "unprognostic (3.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.68e-2)" "unprognostic (3.00e-1)" "unprognostic (4.75e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "prognostic favorable (6.92e-9)" "unprognostic (3.91e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.98e-1)" 41.8 54.3 31.8 9.8 32.9 16.8 39.9 32.3 41.3 33.6 34.2 53.8 18.8 32.8 38.5 34.9 34.5 12.7 70.6 31.0 31.8 59.0 93.1 33.4 16.7 31.9 32.3 31.7 79.4 34.8 41.2 11.9 31.7 42.5 20.8 8.9 42.4 21.4 80.2 41.4 41.1 13.8 32.1 39.9 65.4 33.9 33.8 20.3 43.7 41.2 21.8 45.6 31.8 32.4 9.6 21.8 16.5 23.5 39.7 22.0 35.6 11.5 27.8 18.9 16.5 29.6 32.6 13.0 16.3 18.2 27.6 27.8 20.4 27.6 15.0 23.8 13.3 13.2 31.5 23.4 46.9 21.1 13.5 26.3 47.8 13.2 32.1 23.1 14.9 33.2 13.7 26.3 21.0 42.4 26.7 21.8 18.6 86.9 22.1 18.2 24.7 40.8 31.4 20.4 16.2 45.0 26.2 34.2 30.6 22.4 50.1 15.8 12.2 23.3 14.3 16.1 11.6 32.2 51.9 16.3 22.1 10.3 24.0 10.7 11.6 24.1 6.6 7.8 7.9 23.9 9.8 9.0 10.2 19.3 14.0 7.7 11.1 6.5 7.1 13.4 14.9 5.6 31.8 32.9 32.3 41.3 31.0 31.8 31.9 32.3 31.7 32.1 33.8 32.4 46.2 28.9 29.6 5.2 55.6 46.5 54.9 56.1 43.3 24.4 85.5 97.3 94.6 75.8 44.0 68.0 6.2 93.4 55.7 114.0 137.0 90.4 48.3 54.5 25.2 36.8 53.8 32.2 4.8 101.0 87.5 38.3 41.8 36.9 22.9 44.3 50.3 158.1 101.1 28.6 5.6 74.3 99.7 93.2 83.6 127.1 52.2 60.3 69.4 4.7 96.9 95.2 62.8 4.5 10.4 71.9 102.1 48.2 74.3 56.1 215.0 174.5 45.1 25.3 32.9 41.5 56.6 66.2 94.4 50.4 49.0 80.6 51.5 52.6 79.6 63.4 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SVOPL MGC46715 ENSG00000157703 "SVOP like" Q8N434 7 138594285-138701362 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 4.1;salivary gland: 4.0" "Cell type enriched" "Detected in some" 8 "granulocytes: 76.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "HMC-1: 8.8;MOLT-4: 2.0;NTERA-2: 1.9;RT4: 2.0;T-47d: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA018035 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA018035: AB_2197028" "unprognostic (6.70e-5)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (2.49e-1)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "unprognostic (7.69e-3)" "unprognostic (2.59e-3)" "unprognostic (7.16e-2)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (5.03e-3)" "unprognostic (2.22e-4)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (8.51e-2)" 0.0 2.0 0.6 0.1 0.5 0.2 0.9 0.2 0.4 0.5 2.5 0.9 0.1 0.2 0.8 0.1 1.8 0.0 0.2 0.5 0.6 2.7 0.0 0.2 0.1 0.8 0.8 0.5 0.5 4.1 0.9 0.6 0.5 0.4 0.3 3.2 4.0 0.8 0.0 0.3 0.2 0.0 0.6 0.1 0.1 0.9 0.7 0.5 0.7 0.0 0.0 0.4 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 2.0 1.1 1.9 0.0 0.0 0.5 0.0 0.1 0.0 2.0 0.1 0.6 0.0 0.4 0.0 0.3 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.2 0.4 0.5 0.6 0.8 0.8 0.5 0.6 0.7 0.7 0.0 0.0 1.9 0.7 0.0 0.1 1.9 2.0 0.0 0.6 1.2 1.4 2.1 0.0 3.1 1.8 0.0 3.7 0.4 0.4 0.0 0.0 0.7 8.2 0.1 0.1 0.0 5.5 1.1 0.0 0.8 0.3 0.0 0.9 76.0 1.2 0.0 0.1 0.1 0.0 1.8 0.1 4.1 0.0 0.2 0.5 0.6 0.1 0.0 0.0 0.1 0.5 0.0 1.0 1.5 0.1 0.0 0.4 0.1 0.2 0.1 0.0 5.6 8.6 0.0 0.0 0.3 2.2 0.7 0.0 0.1 1.9 0.7 0.3 0.5 0.5 SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;heart muscle: 26.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 157.4;Microglial cells: 472.2;Oligodendrocytes: 214.3" "Cancer enhanced" "Detected in many" "glioma: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 15.4;RH-30: 43.4;RPMI-8226: 43.6;SCLC-21H: 10.0;U-87 MG: 26.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA044271: AB_2732515, HPA059267: AB_2683961" "unprognostic (9.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.17e-1)" "unprognostic (9.56e-2)" "unprognostic (5.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.94e-2)" "unprognostic (7.75e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.16e-6)" "unprognostic (1.40e-3)" 1.8 0.9 23.7 1.5 23.2 0.0 0.5 27.6 26.8 3.2 8.6 0.8 1.2 3.2 0.7 0.2 4.2 8.8 26.9 21.1 21.0 4.9 0.0 0.7 2.0 28.4 23.0 0.9 0.7 0.2 0.7 0.2 28.4 3.3 0.9 1.8 0.3 12.3 0.1 0.2 2.1 2.2 27.8 0.7 1.6 0.8 25.3 1.6 4.8 0.1 2.4 1.7 2.0 36.4 0.0 0.3 2.6 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 15.4 0.0 0.8 0.0 0.0 2.6 0.0 0.0 0.0 43.4 43.6 0.0 0.0 10.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 23.2 27.6 26.8 21.1 21.0 28.4 23.0 28.4 27.8 25.3 36.4 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.2 0.7 0.6 1.2 0.0 0.0 157.4 0.0 0.0 2.0 0.0 0.8 0.0 21.9 0.0 0.0 0.1 3.3 69.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 472.2 0.0 1.9 0.0 41.7 214.3 1.5 0.0 7.2 0.0 0.0 0.0 5.9 0.0 0.5 0.0 0.5 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SYNDIG1L "capucin, DSPC1, IFITMD4, TMEM90A" ENSG00000183379 "Synapse differentiation inducing 1 like" A6NDD5 14 74405894-74426210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 42 "brain: 468.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.7;Bipolar cells: 10.9;Inhibitory neurons: 4.8" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.1" "Region enriched" "Detected in all" 5 "basal ganglia: 468.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "basal ganglia: 280.7" "Region enriched" "Detected in many" 7 "basal ganglia: 125.1" "HPA042594, HPA048487" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 56: Bipolar cells - Visual perception" "HPA042594: AB_2678069, HPA048487: AB_2680416" "unprognostic (5.75e-2)" "unprognostic (9.96e-3)" "unprognostic (2.25e-2)" "unprognostic (5.51e-2)" "unprognostic (3.08e-3)" "unprognostic (5.72e-2)" "unprognostic (5.83e-2)" "unprognostic (4.51e-2)" "unprognostic (2.83e-2)" "unprognostic (5.74e-2)" "unprognostic (8.85e-2)" "unprognostic (1.63e-1)" "unprognostic (3.85e-2)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" 0.5 0.1 42.9 0.0 468.2 0.0 0.3 1.2 65.4 0.3 0.5 0.4 0.0 0.3 11.0 0.1 0.2 0.2 0.2 3.4 30.8 0.3 0.1 1.4 0.1 16.7 50.9 0.2 0.2 0.0 0.7 0.0 12.9 0.3 0.2 4.6 0.2 0.2 0.2 0.4 0.5 0.3 19.6 0.2 0.2 0.2 100.2 0.0 0.3 0.0 0.0 0.2 0.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.9 468.2 1.2 65.4 3.4 30.8 16.7 50.9 12.9 19.6 100.2 7.5 0.1 0.0 2.7 1.0 0.0 0.4 0.0 0.0 0.0 10.9 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.7;monocytes: 38.9;T-cells: 30.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" 9.9 24.6 73.2 4.9 84.9 92.9 14.7 64.7 121.8 36.2 25.3 26.7 5.9 22.1 11.6 37.3 23.5 11.3 57.0 84.7 37.5 26.2 5.3 8.6 7.5 35.1 37.9 72.7 28.0 29.8 15.2 6.5 36.5 29.6 4.3 73.0 45.1 18.0 29.0 51.8 11.8 13.2 6.3 10.6 16.6 19.8 58.4 3.5 11.6 26.4 9.9 25.6 34.9 67.1 5.4 9.6 17.3 31.1 1.7 4.4 7.5 23.2 40.8 29.2 26.9 2.1 0.6 0.2 5.3 6.1 3.3 7.6 11.8 0.5 8.8 0.1 36.6 0.4 0.8 1.0 4.9 1.6 10.5 6.7 1.8 7.9 0.0 20.7 1.4 6.8 11.0 0.7 4.6 12.5 4.8 4.5 3.6 4.8 18.7 14.0 0.0 1.5 0.9 15.0 27.1 5.5 6.1 25.1 23.7 7.1 36.9 27.3 0.5 0.0 19.6 0.3 0.1 6.4 0.2 15.2 0.8 30.2 31.6 0.6 38.9 0.8 30.8 11.8 1.7 5.8 1.1 9.1 44.7 4.2 1.3 15.3 1.7 5.1 0.6 33.1 0.2 18.0 73.2 84.9 64.7 121.8 84.7 37.5 35.1 37.9 36.5 6.3 58.4 67.1 8.9 9.6 1.1 28.4 21.0 30.3 73.6 33.8 39.3 112.9 61.4 73.0 73.6 75.8 31.4 66.2 27.1 25.0 52.5 0.1 15.6 57.2 40.0 14.3 24.4 9.5 0.0 92.9 57.1 12.3 14.4 44.6 1.5 18.5 2.5 49.0 12.1 5.9 14.2 47.1 47.1 0.3 12.2 20.0 13.8 87.9 133.3 11.7 140.5 20.6 10.1 46.8 91.6 39.7 18.7 21.7 1.1 119.2 23.2 36.4 0.1 9.3 7.5 38.6 19.7 46.8 30.6 62.8 14.7 57.1 37.4 13.1 21.2 131.6 0.4 80.2 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYNGR3 ENSG00000127561 "Synaptogyrin 3" O43761 16 1989660-1994275 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 122.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.2;Inhibitory neurons: 33.7;Spermatogonia: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.0;T-cells: 1.1" "Cell line enhanced" "Detected in many" "HDLM-2: 49.9;HMC-1: 30.3;Karpas-707: 25.8;SK-BR-3: 32.1;U-266/70: 40.2" "CAB034278, HPA042842" Enhanced Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB034278: AB_2200905, HPA042842: AB_2678198" "unprognostic (8.89e-3)" "prognostic favorable (6.92e-4)" "unprognostic (6.07e-3)" "unprognostic (2.94e-3)" "unprognostic (2.92e-2)" "unprognostic (8.06e-3)" "unprognostic (2.52e-1)" "unprognostic (5.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.06e-1)" "unprognostic (3.69e-3)" "unprognostic (1.05e-1)" "prognostic favorable (7.12e-7)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.79e-1)" "unprognostic (8.78e-2)" 0.3 9.4 83.0 2.9 86.4 0.9 0.3 35.7 106.5 0.5 10.6 5.3 1.3 0.2 0.0 0.5 0.4 0.4 0.9 74.7 110.7 3.8 0.3 1.0 3.2 88.2 95.3 0.6 0.8 7.3 12.3 1.6 122.6 0.8 1.1 9.5 1.1 0.1 0.1 0.6 5.9 0.7 34.3 2.5 2.3 5.6 121.3 0.5 0.4 0.0 3.7 0.4 1.3 70.5 0.9 4.0 3.7 0.5 0.4 0.4 4.5 1.9 3.1 1.5 1.2 6.3 2.9 6.2 1.4 1.4 4.1 3.5 4.1 0.5 0.4 49.9 2.9 0.1 5.9 3.1 2.1 0.0 30.3 0.9 0.2 0.1 1.0 7.2 0.4 1.9 17.9 25.8 0.7 4.7 0.3 0.3 19.0 0.7 1.8 0.0 0.5 4.9 2.4 0.1 8.6 10.7 4.4 32.1 0.4 2.0 4.5 0.4 0.7 0.9 14.5 0.1 0.7 40.2 5.0 7.2 0.6 5.5 0.6 0.0 0.3 0.0 0.3 0.1 0.8 1.2 0.6 1.1 0.3 1.9 0.7 0.3 0.0 2.0 0.3 0.0 0.6 0.4 83.0 86.4 35.7 106.5 74.7 110.7 88.2 95.3 122.6 34.3 121.3 70.5 0.1 0.0 0.6 3.3 5.0 0.3 0.8 0.6 1.2 5.0 0.2 0.3 5.4 0.0 0.6 0.0 2.1 0.5 2.1 0.9 1.9 2.0 0.8 0.0 0.1 0.5 0.0 0.0 24.2 0.5 0.8 1.2 0.5 0.1 1.3 1.4 0.0 0.0 0.3 6.7 33.7 0.5 0.0 0.6 0.4 0.5 0.0 0.5 0.0 1.9 2.7 1.1 2.1 2.5 3.5 1.2 0.0 0.0 2.3 5.5 0.1 0.1 0.9 2.1 0.0 0.1 0.3 3.0 8.6 0.4 0.3 3.1 2.9 0.4 0.3 1.7 SYNGR4 ENSG00000105467 "Synaptogyrin 4" O95473 19 48364367-48376377 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 54.4" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 159.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 9.8;SCLC-21H: 24.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030075, HPA059286" Enhanced Approved "Golgi apparatus" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus" "HPA030075: AB_10610559, HPA059286: AB_2683965" "unprognostic (1.58e-2)" "unprognostic (3.44e-2)" "unprognostic (3.18e-2)" "unprognostic (9.49e-4)" "unprognostic (2.51e-2)" "unprognostic (7.10e-2)" "unprognostic (2.52e-3)" "unprognostic (3.72e-3)" "unprognostic (2.87e-2)" "unprognostic (6.19e-2)" "unprognostic (6.69e-2)" "unprognostic (2.41e-2)" "unprognostic (2.02e-7)" "unprognostic (1.06e-2)" "unprognostic (1.74e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" 0.0 0.0 0.4 0.0 0.4 0.1 0.0 3.0 1.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.6 0.0 0.1 0.0 0.0 0.4 0.5 0.0 1.0 3.9 0.3 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 54.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 9.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.5 3.2 0.5 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.1 3.6 0.1 0.3 0.5 0.2 0.0 0.7 1.8 0.7 0.0 2.8 0.0 0.0 24.1 0.6 0.1 0.4 0.0 0.0 0.4 0.1 0.1 0.0 0.8 0.0 0.0 3.2 1.1 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.0 1.0 0.8 0.6 0.4 0.5 0.4 0.4 0.4 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 32.6 0.0 0.1 0.1 9.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 0.0 24.6 0.9 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 6.6 0.0 0.0 159.5 33.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 SYNPR "MGC26651, SPO" ENSG00000163630 Synaptoporin Q8TBG9 3 63228315-63616924 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 123.6;retina: 38.8" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 641.5" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Region enhanced" "Detected in all" "olfactory bulb: 743.6" "Low region specificity" "Detected in all" "HPA051368, HPA061671" Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051368: AB_2681456, HPA061671: AB_2684582" "unprognostic (1.69e-1)" "unprognostic (3.77e-2)" "unprognostic (3.14e-3)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (1.93e-1)" "unprognostic (2.50e-1)" "unprognostic (5.32e-2)" "unprognostic (1.82e-1)" "unprognostic (1.89e-1)" 0.0 0.3 40.0 0.1 123.6 0.0 0.0 52.1 68.7 0.0 5.7 0.2 0.2 0.0 0.0 0.0 0.0 0.0 4.5 42.5 19.0 0.0 0.0 0.0 0.0 21.9 22.8 0.0 0.1 0.0 1.1 0.0 11.2 0.0 0.1 38.8 0.6 0.0 0.0 0.0 0.1 0.0 25.9 0.0 0.5 0.0 41.2 0.0 0.2 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 123.6 52.1 68.7 42.5 19.0 21.9 22.8 11.2 25.9 41.2 40.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 5.3 0.0 72.4 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.0 641.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 45.0 0.0 8.0 7.6 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 7.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 SYP MRX96 ENSG00000102003 Synaptophysin P08247 X 49187815-49200199 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 259.4;pituitary gland: 106.8;retina: 316.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 529.2;Cone photoreceptor cells: 546.3;Rod photoreceptor cells: 594.4" "Group enriched" "Detected in many" 6 "glioma: 12.8;pancreatic cancer: 5.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "K-562: 20.3;SCLC-21H: 102.6;SH-SY5Y: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000076, HPA002858, CAB055505, CAB078999, HPA079659" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB000076: AB_2315411, CAB055505: AB_564017, CAB078999: , HPA002858: AB_1080153, HPA079659: " "unprognostic (2.08e-1)" "unprognostic (8.72e-2)" "unprognostic (1.56e-1)" "unprognostic (5.37e-3)" "unprognostic (4.37e-2)" "unprognostic (2.11e-1)" "unprognostic (1.87e-1)" "unprognostic (6.46e-5)" "unprognostic (8.52e-3)" "unprognostic (1.62e-1)" "unprognostic (3.44e-3)" "unprognostic (8.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.94e-1)" 2.6 40.1 115.7 3.6 132.0 0.8 1.9 26.0 259.4 1.8 0.0 7.4 12.4 1.5 2.0 1.2 1.7 0.8 3.1 144.0 137.9 5.0 0.8 3.0 0.9 89.5 25.8 1.7 7.6 3.3 106.8 0.8 76.2 1.6 3.9 316.3 1.3 1.1 1.9 1.8 13.9 1.9 4.7 2.0 5.3 1.7 86.0 4.2 2.3 1.4 0.7 1.5 2.2 116.9 0.9 3.9 2.9 5.8 3.2 0.5 0.4 0.2 0.1 0.7 0.8 3.6 2.1 3.2 0.5 0.1 4.4 2.9 3.1 0.4 0.7 6.5 3.5 4.9 1.4 1.1 0.1 0.6 10.5 0.4 0.1 0.5 0.7 0.4 0.3 2.7 20.3 7.6 0.6 1.1 1.7 0.4 9.6 2.5 0.8 0.6 0.6 1.5 0.2 0.4 102.6 36.8 1.1 0.4 1.5 0.9 1.9 1.8 0.6 0.6 3.2 1.0 0.4 0.5 6.7 0.8 1.7 1.3 3.2 0.7 0.2 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.4 0.1 0.1 1.9 0.2 0.1 0.6 0.1 0.0 115.7 132.0 26.0 259.4 144.0 137.9 89.5 25.8 76.2 4.7 86.0 116.9 7.5 0.0 3.9 24.2 6.3 2.5 2.8 1.0 1.2 529.2 5.8 8.1 1.8 2.8 2.9 9.2 546.3 1.1 1.9 11.3 0.0 0.9 10.3 1.4 3.1 6.5 116.4 0.4 115.1 2.6 0.6 3.7 10.2 3.1 8.8 3.4 6.1 1.2 1.2 122.8 118.4 37.7 10.2 1.9 4.9 12.6 4.1 3.6 3.6 17.8 2.7 54.4 3.1 28.1 33.7 1.2 2.1 3.8 1.5 1.5 16.3 0.9 4.6 594.4 6.6 5.4 7.8 2.4 2.8 3.4 2.6 1.4 3.5 41.3 10.8 1.0 SYPL1 SYPL ENSG00000008282 "Synaptophysin like 1" Q16563 7 106090505-106112576 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 633.6;Spermatocytes: 536.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014141 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA014141: AB_1857716" "unprognostic (8.88e-2)" "unprognostic (8.10e-2)" "unprognostic (3.39e-3)" "unprognostic (1.47e-1)" "unprognostic (4.76e-2)" "unprognostic (4.61e-2)" "unprognostic (8.74e-2)" "unprognostic (9.15e-2)" "unprognostic (3.71e-2)" "unprognostic (2.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic favorable (1.25e-9)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-1)" 78.7 70.1 35.3 49.2 50.2 51.2 98.3 55.5 63.5 93.6 34.8 83.1 60.4 100.0 88.9 147.2 104.1 70.1 73.3 33.4 41.1 127.2 66.6 66.9 86.0 71.6 50.8 72.1 54.3 125.8 26.3 84.1 69.5 96.8 77.1 13.0 135.8 119.8 149.6 94.0 58.2 109.4 56.2 59.8 81.7 97.6 44.8 56.7 117.4 101.6 121.4 107.5 94.8 82.8 187.1 85.3 44.9 74.4 188.8 142.9 65.0 115.0 128.3 105.8 128.5 58.5 323.6 187.0 150.9 144.2 179.5 154.9 72.4 186.0 174.8 51.6 85.5 82.6 49.5 57.4 148.0 140.7 65.5 107.5 236.7 111.1 142.8 140.9 147.9 69.5 85.5 0.4 212.7 161.3 149.3 167.1 49.8 214.5 112.6 18.4 75.7 97.7 224.4 300.4 22.1 50.1 111.3 266.4 115.6 106.8 81.6 111.0 133.2 210.3 107.3 226.0 132.4 82.1 102.2 193.7 92.6 239.8 121.0 66.9 39.8 44.8 13.6 37.9 28.2 130.3 36.3 27.3 32.5 125.1 53.5 34.3 15.2 71.3 31.2 31.3 33.9 40.9 35.3 50.2 55.5 63.5 33.4 41.1 71.6 50.8 69.5 56.2 44.8 82.8 186.9 54.5 63.4 27.1 238.6 171.7 285.3 326.6 252.6 8.9 111.5 70.4 69.7 181.6 172.9 187.6 16.7 211.6 45.9 51.6 113.5 167.0 633.6 96.6 57.3 153.3 37.8 81.2 8.4 107.5 144.7 125.1 88.7 87.7 91.4 47.9 152.4 96.5 90.5 20.2 7.6 82.7 175.0 83.4 95.3 170.3 95.1 69.4 145.9 16.9 39.4 103.9 15.5 8.5 70.8 130.0 66.2 94.0 23.8 213.6 61.0 221.4 131.2 12.8 157.8 76.3 144.4 536.4 126.3 309.0 173.0 184.0 79.5 113.6 101.1 271.8 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 184.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.7;Kupffer cells: 2.4;Leydig cells: 2.8" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 4.2;U-87 MG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 0.9 0.3 1.3 2.5 1.2 0.4 0.8 1.5 1.7 10.3 0.2 184.0 5.0 25.2 0.2 14.7 20.4 0.5 3.2 1.7 0.1 0.3 0.5 0.7 0.3 0.0 0.2 1.8 0.3 0.0 0.2 0.2 0.1 6.2 9.1 4.1 0.5 1.1 2.8 1.1 31.4 33.1 0.0 0.3 37.9 0.7 0.0 0.1 0.4 0.2 0.1 32.3 8.5 0.4 0.9 0.6 0.2 0.3 1.4 0.1 0.1 0.2 0.1 0.2 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.8 0.1 0.0 1.4 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.2 0.2 0.8 0.9 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.6 1.2 4.2 0.1 0.5 0.1 0.3 1.4 0.2 0.6 0.5 0.5 0.6 0.1 2.3 0.1 0.8 0.2 0.4 0.0 0.1 1.3 0.1 0.3 0.2 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 1.3 1.2 1.5 1.7 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.0 0.5 0.3 0.1 0.6 0.2 0.2 0.0 0.2 1.1 1.4 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.6 0.0 0.2 1.4 0.1 1.2 6.7 0.1 0.3 0.0 2.4 0.4 0.1 2.8 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.4 0.1 1.5 0.2 0.0 1.1 0.7 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.4 TAF1B "RAF1B, RAFI63, SL1, TAFI63" ENSG00000115750 "TATA-box binding protein associated factor, RNA polymerase I subunit B" Q53T94 2 9843443-9934416 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071254 Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA071254: " "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (8.58e-5)" "unprognostic (1.44e-3)" "unprognostic (5.43e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.94e-7)" "unprognostic (9.17e-2)" "unprognostic (3.29e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (2.98e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.59e-1)" "unprognostic (2.49e-1)" "unprognostic (2.79e-2)" "unprognostic (1.49e-2)" 7.2 7.6 4.1 8.4 4.1 7.1 8.7 5.3 4.2 6.9 6.4 5.9 5.1 9.7 6.6 9.6 9.6 7.2 4.8 3.8 5.1 13.3 6.3 8.7 11.4 3.9 5.4 5.7 4.4 14.7 3.7 13.0 3.7 9.0 5.7 9.0 8.1 9.0 2.8 8.6 4.2 8.1 3.8 7.1 6.1 11.0 5.4 11.4 10.5 3.4 12.7 7.9 6.0 4.7 25.1 20.4 29.2 9.6 14.1 21.2 52.7 29.9 23.3 25.3 23.3 19.1 18.1 27.1 13.6 21.3 26.7 15.0 26.9 31.7 27.3 31.3 35.9 31.5 8.9 28.3 19.5 22.1 32.4 17.0 16.5 21.4 28.5 20.8 37.4 14.8 19.8 27.2 25.0 15.3 16.6 20.1 37.7 15.6 17.5 10.2 27.2 8.0 24.9 24.3 12.3 33.6 23.5 28.9 21.9 18.9 10.4 17.4 20.4 31.9 39.8 31.1 35.7 14.9 19.9 39.7 18.4 24.8 26.7 3.6 9.1 6.2 12.1 15.5 12.1 11.1 10.2 14.3 13.4 11.7 6.3 10.0 0.5 10.2 12.4 10.6 11.1 5.2 4.1 4.1 5.3 4.2 3.8 5.1 3.9 5.4 3.7 3.8 5.4 4.7 12.5 19.2 22.0 22.2 13.1 16.2 29.9 17.9 19.9 24.5 8.0 6.1 4.0 2.8 26.0 12.9 27.1 25.0 12.6 2.4 13.7 19.5 11.6 26.8 21.0 15.4 1.8 10.5 38.8 18.9 37.4 18.4 13.7 17.3 8.8 12.7 6.8 4.7 12.7 15.2 27.1 3.3 8.2 12.0 11.5 3.8 19.0 14.6 0.0 15.0 15.5 25.5 15.5 32.6 23.5 15.7 3.8 13.2 16.6 9.5 1.7 26.5 29.7 21.0 19.7 15.9 16.2 47.6 33.9 19.7 13.2 23.7 15.1 24.8 4.4 18.7 TANGO6 "FLJ12688, KIAA1746, TMCO7" ENSG00000103047 "Transport and golgi organization 6 homolog" Q9C0B7 16 68843531-69085182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 110.2;Excitatory neurons: 45.4;Inhibitory neurons: 57.4;Late spermatids: 50.5;Oligodendrocyte precursor cells: 38.7;Oligodendrocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041312 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" Cytosol "HPA041312: AB_10796342" "unprognostic (8.55e-2)" "unprognostic (6.64e-2)" "unprognostic (4.66e-2)" "unprognostic (1.94e-2)" "unprognostic (3.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.50e-1)" "unprognostic (1.86e-1)" "unprognostic (2.22e-1)" "unprognostic (9.82e-3)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.20e-4)" "unprognostic (1.55e-2)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (6.02e-2)" 5.1 3.0 2.8 4.5 3.8 3.4 4.6 3.5 3.4 4.8 4.9 3.9 2.4 4.3 1.9 3.6 3.8 2.8 3.2 2.6 3.6 5.7 12.9 3.6 4.9 2.7 3.1 4.2 3.2 6.0 2.5 3.4 2.8 4.0 3.1 4.2 3.2 4.2 8.8 4.2 3.1 4.8 2.4 4.5 4.1 4.3 3.5 4.7 3.3 5.7 4.6 5.5 4.2 3.9 7.1 14.3 4.6 9.9 7.6 8.6 3.3 9.5 7.7 11.5 9.3 9.1 5.7 15.8 5.1 13.2 6.0 5.8 10.6 12.8 14.0 3.8 6.3 3.0 5.4 8.5 6.3 8.0 7.2 6.6 6.7 16.3 14.7 4.7 11.2 7.6 10.6 2.7 10.7 7.1 8.3 6.4 10.2 6.9 7.6 8.9 6.8 17.8 8.4 3.9 4.8 5.6 23.3 1.3 6.3 5.5 4.6 8.9 6.5 10.9 3.9 11.2 6.8 4.9 4.5 10.7 6.9 3.0 7.4 0.0 3.8 2.0 3.4 6.6 3.5 2.7 3.3 3.5 4.8 2.4 2.0 3.3 0.2 2.0 6.2 1.3 4.9 3.1 2.8 3.8 3.5 3.4 2.6 3.6 2.7 3.1 2.8 2.4 3.5 3.9 5.1 0.0 4.2 23.5 5.4 5.2 9.5 5.0 2.8 8.8 1.5 1.8 3.8 5.7 2.2 7.3 10.4 5.6 3.1 2.1 0.0 2.2 110.2 1.5 3.5 4.8 0.0 7.8 45.4 3.3 2.7 4.0 6.1 3.0 1.3 3.7 3.9 12.3 4.7 5.0 57.4 1.8 4.1 7.6 3.5 50.5 5.6 4.2 5.4 25.3 3.5 3.3 4.1 38.7 51.3 2.7 4.4 3.4 2.9 3.7 1.1 6.0 0.5 10.5 0.0 3.9 3.4 5.7 4.7 4.0 3.0 2.5 7.0 3.2 2.2 9.2 TBC1D20 "C20orf140, dJ852M4.2" ENSG00000125875 "TBC1 domain family member 20" Q96BZ9 20 423596-462566 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043613 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA043613: AB_10963930" "unprognostic (2.16e-3)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-3)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.54e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "unprognostic (2.97e-1)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" 16.8 21.5 21.7 7.6 24.2 7.0 16.0 22.6 22.4 18.4 17.0 19.1 8.6 17.4 15.6 18.9 16.1 11.8 16.6 20.4 21.6 14.4 13.4 18.1 10.6 23.1 23.6 17.3 14.7 21.2 17.8 17.5 22.2 17.7 11.8 7.7 16.9 18.8 20.4 20.0 14.5 20.4 22.3 16.1 15.4 9.9 23.0 14.6 15.0 23.6 12.9 19.6 16.8 23.4 18.5 12.6 18.2 15.9 75.9 39.3 16.3 19.8 39.1 27.7 29.4 11.8 9.6 8.4 4.6 43.7 35.2 18.1 18.8 20.2 26.8 4.9 4.9 13.4 4.0 27.3 45.7 13.1 7.1 35.2 38.3 15.4 14.4 29.9 17.7 14.4 14.8 17.7 30.7 4.5 12.1 15.5 10.6 23.7 11.0 12.0 17.2 10.4 18.7 12.0 15.8 12.8 22.2 39.9 53.5 20.0 14.1 27.9 19.9 25.0 8.9 22.2 14.3 9.7 19.0 7.7 13.4 14.0 15.9 3.0 0.6 0.7 1.8 0.5 1.2 0.8 1.2 2.1 0.6 0.7 1.1 1.8 1.5 0.9 0.4 0.6 0.8 0.7 21.7 24.2 22.6 22.4 20.4 21.6 23.1 23.6 22.2 22.3 23.0 23.4 23.0 12.8 13.6 16.3 22.6 18.5 13.6 11.3 23.3 29.3 22.4 14.4 16.8 24.3 11.1 14.7 12.5 16.5 28.9 29.6 11.7 23.8 48.9 21.3 26.9 20.7 16.1 48.6 16.2 30.3 25.1 23.0 17.9 16.2 11.4 14.4 25.4 19.7 19.7 26.9 19.2 17.9 8.2 17.6 16.4 147.2 29.5 18.6 14.2 14.0 13.2 21.4 43.3 11.6 15.2 22.5 20.7 35.3 30.0 21.2 19.4 17.0 17.1 19.4 19.7 22.1 18.3 33.1 34.7 15.3 18.9 50.9 24.0 19.6 15.7 27.9 TBC1D32 "bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235" ENSG00000146350 "TBC1 domain family member 32" Q96NH3 6 121079494-121334745 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.4" "Cell type enhanced" "Detected in many" "Astrocytes: 68.2;Excitatory neurons: 124.1;Inhibitory neurons: 87.4;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 102.6;Rod photoreceptor cells: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013413 Uncertain Approved Mitochondria NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA013413: AB_10602702" "unprognostic (3.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.12e-3)" "unprognostic (4.82e-2)" "unprognostic (2.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.60e-4)" "unprognostic (7.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (8.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.73e-2)" "unprognostic (1.57e-2)" "unprognostic (7.62e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" 1.2 2.4 0.8 0.9 1.5 0.8 1.7 0.6 1.4 1.8 0.9 1.1 1.8 1.7 0.8 1.0 1.6 1.9 0.7 0.8 1.6 1.4 0.4 0.9 1.0 1.1 1.4 1.8 1.3 2.3 1.5 2.9 1.2 1.6 0.7 7.4 0.8 0.9 0.2 1.2 1.4 0.8 0.6 1.0 1.3 3.6 1.8 1.6 2.4 0.5 1.1 1.0 0.9 2.5 1.7 2.0 3.4 4.4 2.8 4.5 1.8 1.9 2.9 3.2 4.6 0.1 1.3 3.4 3.2 2.0 4.7 1.5 1.6 1.6 4.0 22.7 2.2 3.9 0.7 0.7 1.2 2.1 1.5 1.7 1.2 2.8 2.1 3.8 0.7 3.9 2.2 0.0 2.5 1.0 2.3 1.3 1.9 1.1 0.7 2.1 1.6 0.3 1.6 0.8 6.5 3.5 2.2 1.4 1.0 1.8 2.1 1.6 0.4 2.1 2.1 0.6 2.2 1.6 0.0 1.3 3.0 1.1 3.3 6.1 0.9 1.3 1.8 0.5 1.3 2.5 1.4 1.3 0.7 4.5 2.6 2.0 0.8 2.6 0.9 8.2 1.6 0.3 0.8 1.5 0.6 1.4 0.8 1.6 1.1 1.4 1.2 0.6 1.8 2.5 3.9 3.2 8.4 68.2 6.4 6.1 3.7 3.1 9.6 26.2 6.1 5.0 3.1 4.3 10.1 7.3 43.8 4.4 8.7 3.4 0.0 2.4 9.8 8.8 9.5 3.5 5.4 1.7 124.1 2.2 1.7 6.2 10.2 4.7 3.8 26.7 2.9 1.1 1.4 13.5 87.4 6.0 4.1 1.6 2.9 3.5 2.5 2.8 1.8 36.5 1.5 6.7 3.1 105.6 102.6 1.0 3.9 1.9 1.8 2.3 8.0 1.5 20.3 110.4 0.0 6.6 5.3 21.5 7.9 3.4 5.1 2.3 4.9 4.8 4.8 2.3 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" NA NA 4400000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" 21.3 25.3 8.6 15.7 9.0 5.1 25.2 9.1 11.3 26.3 24.0 22.1 17.6 24.8 65.0 17.0 35.4 22.7 18.4 8.8 9.8 32.5 26.8 19.4 14.3 9.7 9.5 30.6 27.1 69.9 22.8 26.9 9.5 25.6 25.6 22.2 25.4 27.7 9.5 20.5 15.4 26.8 9.2 17.3 19.1 19.4 9.6 14.0 70.6 11.5 18.0 23.9 18.6 9.2 34.0 54.1 44.1 89.3 93.6 74.6 25.7 45.3 94.8 46.9 55.3 35.4 57.3 31.3 40.1 60.4 49.8 46.7 43.9 54.5 56.5 33.6 36.4 10.9 21.6 49.2 46.9 37.4 22.8 65.2 49.2 46.6 72.4 88.0 80.7 27.7 21.0 40.3 63.4 32.5 23.4 27.9 12.1 49.7 38.1 25.3 33.9 38.3 67.8 23.3 11.5 24.5 37.7 18.5 52.6 40.8 71.0 35.1 37.9 35.6 24.9 23.9 49.5 18.9 37.9 20.7 57.5 47.1 19.0 6.8 14.2 4.9 25.8 21.9 32.0 28.3 23.1 25.2 45.2 19.4 24.2 20.0 1.6 26.8 24.3 23.6 22.2 21.3 8.6 9.0 9.1 11.3 8.8 9.8 9.7 9.5 9.5 9.2 9.6 9.2 14.8 19.2 16.2 16.6 29.3 14.4 23.7 33.8 31.3 24.0 18.2 15.0 8.5 27.1 20.3 31.3 37.5 50.3 18.8 20.2 7.9 27.2 18.6 25.5 25.7 20.4 13.8 11.6 17.3 20.3 44.2 27.3 11.7 18.3 8.2 29.8 21.4 16.8 28.5 25.2 17.7 12.5 26.4 14.1 59.1 14.1 20.8 18.7 16.0 16.9 14.8 36.7 15.5 20.6 13.7 14.1 12.7 25.2 35.9 19.8 16.2 16.1 27.5 44.4 13.1 23.9 19.8 39.8 34.1 15.3 11.5 31.5 23.0 34.2 23.7 14.6 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TEX10 "bA208F1.2, FLJ20287, Ipi1" ENSG00000136891 "Testis expressed 10" Q9NXF1 9 100302077-100352942 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045434 Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Mitochondria "HPA045434: AB_10965650" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" "unprognostic (1.21e-1)" "unprognostic (8.28e-2)" "unprognostic (5.26e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (2.43e-2)" "unprognostic (3.74e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (3.25e-2)" "unprognostic (2.07e-1)" "unprognostic (7.39e-2)" "unprognostic (3.27e-1)" "unprognostic (2.66e-3)" "unprognostic (9.63e-3)" 9.3 7.0 4.0 8.7 4.3 12.2 9.9 7.2 4.8 9.7 5.2 7.4 5.3 11.2 8.2 9.1 10.2 8.6 6.5 4.3 4.4 6.3 6.9 6.4 14.3 3.9 4.1 11.4 5.7 8.1 5.4 18.8 4.1 7.5 6.8 5.5 6.9 7.4 16.0 12.2 6.5 8.8 4.1 7.9 6.5 22.3 4.9 22.3 8.4 11.6 13.6 10.8 8.7 5.5 26.5 28.5 36.6 41.3 13.2 23.1 56.6 32.7 33.7 41.8 38.7 29.5 30.4 74.6 17.2 21.4 38.3 35.2 52.9 42.1 48.6 30.2 23.3 40.6 17.5 25.8 28.2 59.6 29.1 20.3 23.3 42.5 44.6 20.3 23.1 26.0 46.3 23.8 54.5 41.5 44.0 38.1 75.4 51.1 33.9 42.1 62.2 22.8 30.8 17.0 32.3 27.4 17.9 29.3 29.4 22.4 12.2 17.3 23.6 27.5 24.5 37.3 30.9 16.7 30.6 29.9 28.1 26.3 29.4 18.1 7.4 2.6 9.1 8.9 9.7 12.2 9.0 9.1 9.1 12.9 9.7 11.5 1.8 10.7 6.9 5.3 11.4 7.0 4.0 4.3 7.2 4.8 4.3 4.4 3.9 4.1 4.1 4.1 4.9 5.5 8.6 3.2 9.3 10.7 14.7 22.2 10.6 8.4 20.5 7.8 10.8 8.1 15.4 0.0 13.0 9.2 12.5 53.5 9.6 3.8 3.9 7.7 13.9 11.0 15.8 10.9 5.3 11.1 24.1 8.8 15.7 14.7 5.1 21.9 17.1 13.9 5.0 7.9 9.8 8.4 23.3 5.7 2.0 4.1 8.1 11.4 8.7 8.1 17.8 18.7 7.8 3.4 7.2 21.1 23.9 7.5 5.6 7.9 7.1 9.7 3.0 4.5 5.6 6.5 0.0 14.5 14.7 33.0 33.4 12.9 22.6 46.1 10.3 12.0 6.9 9.5 TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Late spermatids: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA020648: AB_1857908, HPA057116: AB_2683341" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "prognostic favorable (3.90e-6)" "unprognostic (1.69e-2)" "unprognostic (3.84e-2)" "unprognostic (8.34e-2)" "unprognostic (6.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.53e-3)" "unprognostic (5.59e-3)" 16.6 24.2 38.4 7.3 46.9 18.7 19.6 38.3 39.3 17.8 31.1 13.6 10.2 14.7 11.4 17.3 13.4 16.7 27.2 37.6 46.2 18.5 33.2 14.9 6.3 43.5 46.4 15.7 29.4 31.5 11.2 9.9 43.3 16.3 13.5 23.0 19.4 17.0 45.0 15.5 10.2 14.6 40.4 12.7 13.2 53.5 44.9 8.9 40.2 41.9 6.8 10.5 11.1 44.2 32.6 15.2 9.5 19.5 44.7 26.3 11.5 44.1 49.7 39.2 27.0 14.2 7.8 11.3 11.0 55.9 24.3 15.5 17.0 53.3 44.7 16.6 11.6 76.3 9.9 27.0 16.7 22.5 12.2 19.3 29.0 26.7 54.3 27.5 19.1 18.8 21.3 13.6 29.8 36.1 20.5 10.4 5.4 25.3 26.9 12.6 85.8 16.1 22.7 14.9 14.4 24.0 21.9 55.9 24.3 52.2 26.4 19.0 22.6 36.5 21.1 28.5 25.8 14.0 20.1 7.2 14.5 21.0 33.6 0.0 3.1 0.9 1.5 1.0 1.7 0.3 1.7 1.8 2.9 0.6 1.7 1.7 0.3 3.3 2.0 20.6 1.3 1.8 38.4 46.9 38.3 39.3 37.6 46.2 43.5 46.4 43.3 40.4 44.9 44.2 8.1 3.2 8.1 27.4 3.4 8.8 6.8 5.1 16.5 4.2 17.6 13.7 33.3 8.6 6.2 12.9 6.2 2.5 14.7 10.7 1.9 4.7 53.5 6.0 10.5 8.8 12.1 15.4 41.6 8.3 2.0 7.4 16.3 4.2 3.8 12.2 8.6 30.4 12.0 10.1 35.6 11.3 6.1 11.5 3.7 52.9 6.5 9.2 7.2 17.8 2.9 7.2 1.0 33.2 39.3 6.5 4.6 12.8 10.1 7.1 7.1 8.3 8.2 17.3 0.0 12.6 7.4 22.5 8.8 14.6 8.9 1.4 3.6 9.4 10.9 5.4 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" 31.4 48.3 29.3 35.4 30.6 36.8 29.3 31.2 35.8 27.4 34.9 35.2 31.4 25.7 41.1 31.9 20.9 19.0 72.2 31.3 32.5 42.2 80.6 23.7 30.9 30.2 30.6 18.5 23.4 55.8 24.8 31.3 31.0 25.0 38.0 33.3 23.0 28.4 86.1 20.9 23.9 35.3 30.5 24.9 29.1 19.7 30.7 30.3 38.2 94.9 35.8 42.8 23.2 29.4 89.1 88.9 78.5 94.9 64.5 67.2 132.5 138.4 98.0 110.5 98.4 104.8 89.7 122.5 49.7 118.6 81.1 69.2 145.3 82.4 118.3 90.4 90.7 67.7 119.1 99.7 66.7 145.5 69.5 78.0 89.8 113.2 93.9 79.5 117.4 75.4 173.1 66.7 131.7 56.9 78.9 78.3 99.6 88.3 47.0 76.5 91.4 152.6 136.2 83.1 118.0 83.2 84.6 213.5 130.7 98.7 118.5 97.0 95.2 73.6 78.7 86.7 146.4 99.9 115.9 102.3 78.4 109.2 84.2 18.5 32.0 29.2 21.7 44.5 28.6 30.3 23.5 28.1 50.1 23.6 22.4 26.2 7.7 29.7 46.7 33.6 37.0 32.2 29.3 30.6 31.2 35.8 31.3 32.5 30.2 30.6 31.0 30.5 30.7 29.4 31.7 38.5 37.2 9.4 54.7 92.2 100.2 123.3 34.1 24.1 43.2 36.2 129.5 37.1 73.0 38.6 35.5 115.2 44.2 38.8 137.0 94.5 69.7 40.1 55.2 46.0 34.0 36.6 18.1 86.0 187.0 55.9 40.2 48.1 55.2 37.9 32.9 168.0 114.8 35.3 17.4 58.1 81.4 44.0 177.7 32.0 33.5 52.8 53.4 4.7 80.4 49.4 26.8 6.6 14.9 109.4 30.4 38.4 98.6 85.0 37.2 131.8 55.8 31.7 26.3 46.6 75.3 42.6 61.5 60.6 98.9 265.6 46.2 62.9 58.3 118.1 TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" 24.0 42.0 49.8 18.8 51.1 28.2 25.9 50.6 60.6 29.2 47.0 40.3 25.5 27.7 21.0 38.2 29.1 17.6 75.3 50.1 49.6 47.5 48.7 28.1 27.8 49.5 48.9 27.3 33.4 47.6 45.1 23.0 48.9 36.4 19.4 26.2 25.3 27.7 99.1 35.4 32.2 18.0 50.5 37.9 40.5 18.7 50.6 40.7 30.4 83.2 26.8 35.5 28.7 53.1 71.0 127.8 78.7 78.1 24.2 19.3 65.4 31.3 47.7 81.1 52.9 113.3 93.4 51.8 47.4 27.2 131.1 52.5 125.1 68.3 30.4 111.2 140.1 37.6 69.2 101.4 68.3 56.5 35.0 24.9 67.3 60.9 80.8 40.3 37.6 90.1 56.5 118.2 37.8 183.5 89.4 136.7 102.8 93.2 118.3 62.1 51.0 187.8 80.9 41.1 77.6 69.7 48.6 77.0 47.0 98.5 168.7 97.4 26.2 37.1 72.4 89.8 54.9 107.8 137.1 64.3 51.4 100.3 44.6 178.2 123.4 179.9 67.2 123.9 77.4 113.4 67.1 76.3 121.1 113.4 64.8 59.7 139.6 75.7 104.8 127.6 74.4 124.3 49.8 51.1 50.6 60.6 50.1 49.6 49.5 48.9 48.9 50.5 50.6 53.1 23.8 25.6 34.9 4.9 56.5 30.2 52.4 99.0 21.1 40.4 52.9 62.2 40.0 41.5 59.4 73.5 16.7 94.4 45.0 40.2 185.9 94.5 5.6 42.4 25.5 24.6 81.5 48.8 4.3 73.1 94.3 31.0 34.1 37.8 52.0 50.3 24.7 56.0 99.6 35.3 5.6 68.3 91.6 37.6 49.8 7.4 23.9 48.9 44.4 3.7 85.9 48.7 55.6 2.5 9.1 89.9 92.7 23.0 103.7 63.3 102.4 160.0 56.6 43.8 32.9 21.2 45.0 29.0 39.9 52.0 34.4 79.6 48.2 52.7 59.8 61.2 TIMM22 "TEX4, TIM22" ENSG00000177370 "Translocase of inner mitochondrial membrane 22" Q9Y584 17 997129-1003671 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "basophil: 4.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045138 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA045138: AB_10962055" "unprognostic (2.69e-1)" "unprognostic (3.42e-1)" "unprognostic (2.57e-1)" "unprognostic (8.69e-3)" "unprognostic (3.00e-2)" "unprognostic (2.75e-2)" "unprognostic (2.16e-2)" "unprognostic (9.36e-2)" "unprognostic (2.37e-1)" "unprognostic (1.80e-1)" "prognostic favorable (3.42e-4)" "unprognostic (1.27e-1)" "prognostic favorable (1.41e-4)" "unprognostic (2.45e-1)" "unprognostic (3.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.70e-3)" 7.7 9.9 6.6 3.9 7.0 6.8 7.5 9.7 8.6 6.8 8.4 8.5 2.8 7.5 8.8 8.8 6.4 1.6 15.2 6.4 6.8 9.3 6.3 6.2 3.8 7.4 6.8 7.3 7.0 10.3 9.0 6.9 8.1 7.0 4.4 4.5 7.2 1.8 12.3 8.5 6.2 5.2 7.4 7.3 8.4 6.9 7.4 6.2 6.6 12.2 6.0 7.9 6.7 8.3 3.9 0.2 13.0 12.6 19.0 8.8 4.0 12.8 8.5 10.6 13.1 8.4 4.8 4.7 2.5 21.2 9.1 3.6 26.0 14.2 21.0 0.0 0.0 9.5 1.8 0.1 18.6 5.6 1.5 11.3 9.0 13.4 20.6 10.6 17.2 0.3 1.8 13.1 12.9 0.0 17.2 6.6 9.0 11.5 17.0 8.9 6.5 6.5 17.1 0.2 4.6 10.7 4.9 5.3 10.3 12.3 8.1 10.0 18.7 12.5 9.5 10.2 15.7 2.9 0.0 4.2 10.2 8.6 12.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 7.0 9.7 8.6 6.4 6.8 7.4 6.8 8.1 7.4 7.4 8.3 20.2 3.2 15.9 2.0 21.7 43.6 10.7 31.5 17.1 26.4 21.4 18.5 25.3 18.6 17.8 7.3 33.3 62.8 16.3 11.8 37.2 36.2 5.9 14.9 21.2 28.2 20.4 16.8 6.9 28.2 60.8 26.9 17.3 15.8 3.8 27.1 13.9 12.1 40.4 26.9 7.1 11.9 30.5 9.7 18.9 9.7 20.2 14.6 16.0 7.5 26.9 19.1 24.7 4.0 2.8 29.0 8.6 21.4 13.2 17.0 14.2 26.7 10.2 43.7 13.1 17.4 21.4 42.7 47.2 19.5 54.1 61.6 19.0 42.7 16.8 12.9 TIMM23 TIM23 ENSG00000265354 "Translocase of inner mitochondrial membrane 23" O14925 10 45972489-46003742 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA031408 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA031408: AB_10600828" "unprognostic (4.09e-2)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (1.15e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "prognostic favorable (6.79e-4)" "unprognostic (4.41e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-1)" "unprognostic (7.78e-2)" "unprognostic (5.54e-2)" "unprognostic (7.20e-2)" "unprognostic (2.21e-1)" 39.0 50.1 47.1 35.5 48.7 66.4 38.3 50.3 62.9 28.2 55.6 40.1 56.5 26.8 61.9 43.1 28.0 31.7 84.9 49.1 51.6 59.5 74.2 26.6 36.4 50.7 51.5 20.6 32.2 50.5 35.0 35.2 52.3 34.6 39.9 42.9 32.5 36.9 128.5 35.7 37.7 37.6 49.9 25.6 32.8 80.6 50.5 40.0 43.3 134.5 45.4 53.0 27.1 49.0 162.6 167.5 108.7 110.3 88.5 82.4 106.1 130.6 156.1 155.6 164.0 212.8 125.4 144.1 105.7 138.6 111.3 136.1 168.0 139.9 153.3 108.0 165.6 92.1 120.8 231.7 142.2 173.1 98.7 99.4 122.3 133.4 188.0 64.7 146.1 123.0 166.0 78.8 138.7 162.7 155.5 239.0 131.7 119.0 51.8 118.6 105.0 105.5 177.6 111.8 127.3 117.0 72.8 159.4 132.8 83.8 168.7 102.1 108.1 74.8 130.6 96.8 188.9 83.6 148.9 203.2 139.3 246.7 63.9 54.8 98.1 54.3 73.1 131.1 75.7 82.1 70.0 79.1 111.2 79.8 62.5 69.5 22.8 79.1 118.6 92.2 85.8 129.5 47.1 48.7 50.3 62.9 49.1 51.6 50.7 51.5 52.3 49.9 50.5 49.0 13.3 9.6 22.2 10.7 19.4 21.9 18.1 32.7 15.9 14.3 16.0 11.9 97.5 30.0 24.4 12.9 8.4 42.1 17.0 16.1 45.0 40.4 101.5 26.6 20.8 18.3 10.2 43.3 19.1 30.1 47.7 24.8 20.9 23.8 27.8 14.2 13.2 27.3 34.5 0.0 18.6 16.5 36.7 16.0 15.8 35.0 17.7 18.9 23.2 12.2 29.3 23.0 20.6 14.6 19.6 36.7 14.7 11.7 36.0 20.3 22.3 61.0 26.9 10.4 6.6 13.1 26.0 148.7 48.4 38.7 21.6 35.6 16.6 17.0 25.6 22.4 TIMM23B bA592B15.7 ENSG00000204152 "Translocase of inner mitochondrial membrane 23 homolog B" Q5SRD1 10 49942049-49974850 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "unprognostic (8.84e-2)" "unprognostic (2.67e-2)" "unprognostic (5.92e-2)" "unprognostic (4.19e-3)" "unprognostic (9.37e-2)" "unprognostic (7.64e-2)" "unprognostic (2.04e-1)" "unprognostic (1.34e-1)" "unprognostic (3.11e-1)" "unprognostic (1.43e-3)" "unprognostic (4.03e-2)" "unprognostic (3.30e-3)" "unprognostic (5.39e-2)" "unprognostic (9.66e-2)" "unprognostic (1.62e-1)" "unprognostic (4.90e-3)" "unprognostic (1.18e-1)" 5.0 4.4 3.4 4.2 3.9 15.1 5.9 4.1 4.4 3.1 1.8 3.9 6.0 4.6 4.5 4.2 3.1 2.7 9.0 3.0 4.6 3.2 5.5 3.9 3.8 5.2 4.3 3.9 5.1 3.2 4.0 3.6 5.2 4.3 3.8 5.9 3.8 3.6 18.3 6.4 3.9 4.4 4.3 3.5 4.1 3.8 4.6 3.5 3.9 14.7 3.5 5.2 2.9 5.0 4.0 2.2 2.1 4.6 5.1 7.7 2.2 4.8 10.9 4.0 2.2 3.2 5.6 5.8 2.9 14.6 4.0 3.3 1.8 4.8 8.2 6.8 0.3 0.7 0.0 5.8 8.3 11.6 1.0 11.7 2.6 5.4 13.5 3.6 5.7 5.0 5.3 4.4 7.8 0.6 4.9 4.0 5.3 1.2 3.4 3.7 4.4 4.5 3.7 4.4 4.6 10.6 2.5 7.2 5.6 5.0 5.1 4.1 4.9 3.8 3.5 7.5 8.6 5.4 2.6 13.4 9.1 2.6 3.0 1.5 0.9 1.2 1.2 1.1 2.0 1.5 1.1 1.2 1.4 1.0 1.9 1.3 0.3 2.6 2.4 1.2 0.6 1.3 3.4 3.9 4.1 4.4 3.0 4.6 5.2 4.3 5.2 4.3 4.6 5.0 8.2 19.2 10.9 27.4 11.4 0.0 10.1 0.0 10.2 15.2 5.0 4.3 7.1 7.2 5.6 5.5 29.2 5.0 7.7 2.5 1.9 6.1 1.1 9.2 10.8 6.1 0.0 10.3 30.5 8.2 5.4 7.5 10.7 8.3 7.0 8.7 5.3 10.5 5.6 20.2 39.8 2.8 0.0 3.2 0.0 2.3 5.6 5.8 0.0 19.7 9.2 8.0 7.2 24.6 33.3 9.8 1.1 8.6 13.4 9.1 2.9 3.5 2.9 17.5 6.6 9.4 6.7 15.5 9.1 8.0 0.0 5.9 9.3 9.1 3.7 9.7 TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" 10.5 12.0 13.4 10.7 14.3 6.3 13.1 14.2 15.4 15.0 13.2 11.3 8.9 9.3 17.9 15.9 12.8 14.4 44.0 12.7 13.9 17.8 14.2 11.0 17.7 14.3 13.6 10.9 11.1 23.1 7.1 17.1 13.9 13.0 13.7 4.2 14.6 19.7 27.3 15.8 7.7 12.1 14.0 9.9 8.5 10.6 14.1 11.4 19.1 49.2 14.8 14.2 7.0 14.6 26.9 24.5 12.4 10.4 45.5 30.6 27.0 7.7 25.3 21.7 24.7 16.7 16.0 19.5 13.7 27.1 15.1 12.2 30.8 24.8 35.0 16.4 10.9 14.4 10.7 18.8 23.9 11.3 9.1 28.0 37.4 18.4 22.4 13.9 31.5 18.5 19.8 18.1 40.3 33.2 12.0 23.7 16.2 22.4 30.1 10.0 8.4 25.4 32.0 13.1 15.8 29.4 7.8 11.8 28.0 16.2 19.5 30.4 16.1 12.2 9.3 11.3 13.8 12.1 11.8 28.3 20.7 28.5 19.6 11.1 17.6 21.3 10.8 17.6 12.5 16.2 10.4 12.0 17.4 17.6 12.2 10.9 4.3 13.1 20.9 15.1 20.7 22.1 13.4 14.3 14.2 15.4 12.7 13.9 14.3 13.6 13.9 14.0 14.1 14.6 61.2 25.6 39.3 18.6 24.0 37.5 50.4 110.2 31.3 25.0 44.8 55.0 165.3 41.5 63.7 40.5 14.6 157.5 28.9 44.0 150.6 73.2 12.2 39.9 41.1 56.0 28.8 43.1 17.4 62.7 112.7 48.2 29.0 31.1 41.2 34.1 31.8 52.4 86.3 21.9 23.9 43.5 87.5 32.7 40.4 10.0 47.2 39.4 44.4 15.0 65.7 73.6 18.6 22.6 35.6 52.7 40.9 54.5 30.2 43.5 50.5 146.5 63.0 35.4 72.3 43.9 52.5 111.1 58.2 45.9 42.1 177.5 29.7 48.0 45.7 46.7 TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA046058: AB_2679519, HPA055621: AB_2682865" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (1.68e-1)" "unprognostic (2.20e-2)" "unprognostic (5.79e-1)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" 30.9 36.3 25.4 16.5 26.0 23.2 35.8 27.3 36.5 29.4 27.6 27.7 20.5 30.3 45.3 21.4 29.9 26.0 45.4 25.2 27.0 38.8 29.3 27.4 26.5 26.7 27.0 36.4 21.8 41.6 20.4 35.7 26.8 33.3 28.5 26.2 30.1 22.5 40.9 19.8 25.0 29.3 27.1 23.9 24.4 34.9 25.9 25.1 40.6 35.3 20.3 30.1 20.7 28.4 31.3 15.0 22.8 18.2 68.1 66.2 29.2 54.5 55.2 26.4 35.0 9.7 39.0 25.3 70.9 45.9 52.7 34.8 29.2 39.7 40.5 41.3 34.4 28.2 23.0 21.8 66.7 40.9 48.0 74.2 67.0 30.5 38.0 64.4 50.5 33.6 32.7 47.7 64.7 10.1 20.9 32.0 24.9 27.5 21.4 17.9 43.1 31.5 78.4 24.3 25.4 30.9 32.5 64.1 102.6 30.5 35.1 43.2 45.3 35.3 17.8 19.8 41.9 40.0 39.4 30.8 61.3 39.4 31.8 52.8 18.7 44.9 16.1 23.7 16.6 24.2 18.6 19.7 18.6 20.1 17.2 19.9 12.2 23.3 26.8 36.4 24.3 19.4 25.4 26.0 27.3 36.5 25.2 27.0 26.7 27.0 26.8 27.1 25.9 28.4 49.5 41.7 40.2 32.3 49.0 78.3 91.9 205.2 59.2 60.3 67.7 56.6 40.5 48.6 99.9 79.1 60.5 51.2 47.4 46.5 39.2 50.3 6.5 43.3 34.7 59.2 43.9 42.1 42.3 45.3 60.0 84.3 29.0 42.2 61.5 37.6 80.7 54.2 50.3 69.0 46.9 41.3 158.7 58.7 53.8 9.9 79.9 48.1 90.7 43.1 54.1 99.2 63.8 50.3 63.4 54.2 60.4 53.0 51.4 110.0 45.9 67.6 100.0 70.1 39.5 75.3 60.0 172.1 72.5 58.6 76.4 53.5 47.3 42.0 43.0 110.1 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA054064: AB_2682366" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.55e-3)" "unprognostic (1.15e-1)" "unprognostic (8.37e-2)" "unprognostic (2.29e-1)" "unprognostic (8.62e-2)" "unprognostic (2.51e-2)" "unprognostic (5.40e-2)" "unprognostic (4.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (2.92e-2)" "unprognostic (2.63e-1)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" 32.2 38.3 58.9 23.5 62.8 28.2 33.9 57.0 74.7 36.7 51.4 31.1 24.6 40.8 43.5 23.9 34.2 29.6 47.8 62.0 70.1 32.2 58.1 28.1 30.5 54.9 58.7 55.7 30.3 40.6 35.7 31.7 58.5 32.7 24.2 32.3 34.4 35.3 44.5 27.0 26.2 32.1 55.9 29.2 29.1 28.0 61.1 29.5 45.2 55.7 31.7 32.8 28.5 58.0 20.1 48.9 25.6 46.6 71.9 53.1 31.3 25.9 42.6 30.0 33.4 26.4 55.5 32.5 34.9 35.5 50.7 45.9 40.3 33.3 23.7 31.2 88.4 48.7 39.9 45.4 47.2 38.4 55.8 44.2 66.3 18.1 37.4 42.1 42.1 41.5 40.6 47.8 47.9 40.8 28.3 40.2 39.5 90.4 16.2 33.9 32.3 51.0 61.5 52.0 34.3 31.3 35.8 37.4 54.3 43.7 35.5 49.8 33.7 31.6 32.5 21.2 28.9 45.0 71.2 35.3 26.9 47.5 26.7 36.4 40.6 81.9 41.2 41.9 46.4 30.6 33.6 31.6 29.1 44.8 44.1 41.4 69.6 52.4 32.4 24.6 38.4 41.3 58.9 62.8 57.0 74.7 62.0 70.1 54.9 58.7 58.5 55.9 61.1 58.0 52.4 25.6 28.7 22.2 55.8 66.3 58.5 142.3 32.5 47.1 42.6 45.8 35.7 35.8 67.9 42.3 33.3 73.7 51.9 23.0 19.6 61.0 8.0 28.1 38.2 48.8 27.0 30.3 41.5 42.3 64.7 53.7 23.0 44.8 25.3 37.6 60.3 56.6 32.3 69.0 55.3 23.2 91.6 42.1 36.4 10.8 73.7 39.2 26.6 37.5 44.4 60.6 56.7 29.1 45.8 27.8 20.7 62.8 41.3 66.6 32.6 39.5 47.2 46.8 72.3 40.1 67.0 89.3 84.2 25.0 55.4 91.0 55.1 21.5 27.8 40.0 TM4SF19 ENSG00000145107 "Transmembrane 4 L six family member 19" Q96DZ7 3 196319342-196338503 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.0;testis: 4.6" "Cell type enriched" "Detected in some" 8 "Hofbauer cells: 74.6" "Group enriched" "Detected in some" 4 "cervical cancer: 1.4;head and neck cancer: 3.4;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 0.9" "Region enhanced" "Detected in single" "thalamus: 2.5" "Group enriched" "Detected in some" 6 "gdT-cell: 14.8;memory CD8 T-cell: 3.9;naive CD8 T-cell: 4.9" "Lineage enriched" "Detected in single" 16 "T-cells: 14.8" "Cell line enriched" "Detected in many" 12 "GAMG: 427.6" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 71: Testis - DNA repair" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (9.90e-2)" "unprognostic (1.17e-2)" "unprognostic (3.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.67e-1)" "unprognostic (7.19e-2)" "unprognostic (8.90e-5)" "unprognostic (8.86e-3)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.85e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-3)" "unprognostic (4.23e-2)" "unprognostic (4.20e-3)" "unprognostic (2.60e-1)" "unprognostic (1.18e-3)" 6.0 0.3 0.1 0.5 0.2 0.6 2.9 0.3 0.5 1.5 0.0 0.3 0.2 0.3 0.0 3.4 0.3 0.1 0.1 0.2 0.1 0.2 0.5 3.5 0.5 0.1 0.2 0.7 0.3 0.0 0.1 0.8 0.4 0.5 0.2 0.5 1.5 0.0 1.6 1.8 0.2 0.1 0.2 0.6 0.5 4.6 2.5 0.2 0.7 0.5 0.7 0.3 1.7 0.8 15.6 7.2 0.2 0.4 0.9 4.6 0.3 0.0 4.4 1.6 2.9 0.0 8.2 0.2 2.6 0.0 427.6 2.2 0.0 1.7 1.1 0.6 0.0 0.3 2.1 0.0 1.0 0.5 0.4 0.5 1.4 18.8 31.3 0.0 0.0 0.9 9.8 0.9 4.8 1.2 0.1 0.8 0.0 0.2 36.2 0.2 3.2 0.9 0.0 0.4 0.3 0.0 2.5 0.1 0.7 0.4 0.6 0.2 1.4 18.6 15.6 2.9 9.1 0.5 5.6 0.3 20.2 0.7 0.3 0.9 0.3 0.4 14.8 0.4 0.1 0.1 1.3 3.9 0.1 0.3 0.7 4.9 0.6 0.7 0.1 0.6 0.4 1.6 0.1 0.2 0.3 0.5 0.2 0.1 0.1 0.2 0.4 0.2 2.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 74.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 9.3 4.9 4.9 0.0 0.4 0.9 0.1 0.0 0.0 TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 945.8;intestine: 650.8;liver: 703.8" "Group enriched" "Detected in some" 17 "Cholangiocytes: 2070.3;Hepatocytes: 578.1" "Group enriched" "Detected in many" 10 "liver cancer: 249.4;pancreatic cancer: 130.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 22.7;OE19: 20.3;RPTEC TERT1: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Cytosol "HPA046430: AB_2679662" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.83e-1)" "unprognostic (4.66e-2)" "unprognostic (1.91e-2)" "unprognostic (4.97e-1)" 0.3 1.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.0 650.8 0.6 2.3 0.7 0.5 945.8 0.3 0.0 0.0 0.8 703.8 0.3 0.8 0.0 0.0 0.0 72.5 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 514.8 0.9 0.0 0.1 21.3 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.6 0.3 0.2 4.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.8 0.1 20.3 0.0 0.0 0.5 1.4 36.5 0.0 0.6 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.1 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 4.1 2070.3 0.6 0.0 0.0 0.0 0.0 0.8 0.0 25.9 1.1 3.1 0.3 0.6 3.0 13.5 0.1 2.0 0.2 0.1 10.7 3.3 0.0 0.0 7.1 578.1 0.1 0.0 0.1 41.6 0.0 11.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 8.2 17.5 0.0 0.3 0.0 76.6 4.8 0.1 0.0 0.0 0.0 0.7 4.1 0.3 0.0 0.0 0.1 0.5 5.6 2.0 0.2 TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 258.0" "Cell type enhanced" "Detected in all" "Late spermatids: 148.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 553.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" 38.0 48.8 23.1 28.2 25.1 66.0 33.2 19.2 27.3 37.8 34.6 60.5 40.4 29.9 48.6 61.2 40.7 58.3 18.3 23.1 25.2 258.0 138.4 53.7 29.1 25.8 22.8 32.9 117.9 42.4 20.1 36.0 24.6 36.1 69.1 38.9 41.6 43.9 13.7 40.5 35.3 45.8 26.1 32.7 48.7 30.6 26.3 101.4 44.0 35.4 39.9 47.5 28.6 30.7 70.0 147.8 82.6 104.7 122.1 74.3 438.7 74.3 132.8 65.1 109.9 73.3 289.2 80.9 92.3 78.1 61.1 71.5 85.9 553.0 77.0 84.1 46.7 126.9 168.2 134.1 76.7 439.5 84.9 48.7 382.6 144.3 111.7 191.8 177.2 242.2 53.8 60.1 97.1 114.9 232.4 189.3 170.5 266.8 75.4 216.9 131.8 164.2 93.7 278.2 14.4 72.9 84.8 56.6 121.0 391.6 151.8 77.2 62.4 53.9 92.1 140.3 93.4 38.5 97.3 152.9 115.5 133.7 78.5 11.2 7.4 19.0 6.0 8.1 5.4 8.7 8.0 7.8 12.4 13.5 11.1 7.1 6.2 13.7 3.8 10.1 13.9 4.7 23.1 25.1 19.2 27.3 23.1 25.2 25.8 22.8 24.6 26.1 26.3 30.7 23.2 12.8 27.6 28.4 20.2 28.8 52.4 78.7 96.8 50.0 17.2 19.8 10.3 127.2 46.0 42.3 43.8 40.0 35.2 22.2 17.6 62.1 82.4 23.0 5.7 19.4 13.2 49.0 83.1 39.6 15.2 23.5 32.1 21.1 14.0 48.5 22.5 42.5 39.5 23.5 50.4 24.0 28.5 25.7 11.1 148.8 15.5 27.1 65.8 26.2 27.4 30.8 27.8 63.8 40.0 25.3 28.1 23.0 38.2 18.1 25.5 143.7 24.9 38.4 6.6 27.4 18.4 10.1 22.3 65.0 27.8 16.3 21.8 21.6 31.3 37.6 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1803.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2394.6;Late spermatids: 2375.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" 333.4 364.8 332.1 276.3 361.6 315.4 416.8 347.5 376.4 413.7 528.2 493.6 475.8 252.3 640.9 406.3 431.1 360.3 215.5 301.1 358.3 1144.5 1803.2 423.3 292.3 374.4 346.9 281.2 574.2 577.5 133.7 303.1 378.7 383.2 494.4 305.0 479.8 409.3 232.1 231.4 536.1 294.7 351.9 267.8 549.8 247.9 366.9 313.0 596.4 232.3 332.3 406.2 216.5 395.2 609.6 516.6 413.3 381.1 1169.3 645.1 513.6 450.2 854.0 572.0 519.7 837.6 1703.8 380.3 746.9 882.6 598.6 648.1 363.7 659.4 619.2 551.7 390.3 606.2 367.8 414.0 707.7 701.9 959.4 657.5 1511.3 640.9 925.8 809.3 481.6 461.0 556.2 1526.5 662.5 589.5 362.1 424.2 432.1 730.6 392.2 302.8 413.0 651.0 871.5 909.9 319.0 208.7 603.5 786.1 511.2 530.7 989.4 731.6 456.8 522.6 393.9 355.8 396.9 654.2 717.8 326.8 730.9 324.3 260.8 896.4 749.8 795.5 559.9 721.8 587.8 403.6 501.1 558.5 585.5 356.6 438.9 501.8 1242.0 463.8 769.5 587.0 544.8 1813.1 332.1 361.6 347.5 376.4 301.1 358.3 374.4 346.9 378.7 351.9 366.9 395.2 428.2 477.5 455.5 80.6 314.2 261.0 535.0 836.9 222.5 245.8 526.8 337.6 221.0 571.9 766.5 544.4 114.7 406.9 366.7 995.8 131.0 927.3 1504.8 340.5 240.0 321.9 294.9 232.7 43.9 816.9 913.0 336.0 325.7 501.9 257.7 194.5 358.7 2394.6 618.9 180.0 57.3 612.6 598.1 570.6 292.8 2375.1 288.6 458.2 247.3 58.1 540.3 467.7 285.3 94.5 115.5 846.7 651.3 287.3 589.8 550.0 1585.8 809.6 874.1 154.8 170.9 191.7 361.1 458.1 214.7 272.7 235.0 891.0 315.9 372.8 552.2 654.4 TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.1;Paneth cells: 119.7;Proximal enterocytes: 228.6;Respiratory ciliated cells: 155.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 17.3;T-47d: 30.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" 2.3 0.4 0.2 0.4 0.2 0.0 12.5 0.3 0.7 8.7 0.0 38.6 33.1 3.2 0.0 14.8 16.8 8.4 5.7 0.3 0.2 25.5 2.6 11.9 0.1 0.5 0.8 1.1 45.6 4.5 21.0 0.7 0.7 21.6 12.0 0.0 42.1 4.9 1.4 5.4 37.2 0.4 0.2 0.2 31.9 0.5 0.2 0.0 31.3 0.1 0.5 18.9 9.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 17.3 0.0 0.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.7 0.3 0.2 0.5 0.8 0.7 0.2 0.2 0.1 1.5 28.9 30.0 0.7 1.5 2.4 26.9 78.6 24.5 0.3 42.5 19.8 1.7 51.5 94.4 46.0 0.0 22.7 3.7 160.1 13.7 78.2 0.0 59.7 6.6 2.2 41.6 0.0 0.6 64.1 6.1 1.8 102.4 56.2 5.7 0.5 1.1 0.6 3.9 0.0 0.6 92.7 57.0 1.3 3.0 0.1 1.2 3.2 1.8 0.0 2.1 0.1 4.1 1.0 0.7 50.7 119.7 0.7 2.4 22.0 228.6 29.0 155.7 0.5 26.3 0.9 13.6 0.4 1.9 22.0 1.7 23.4 2.8 2.1 77.1 43.1 TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 110.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 108.7;SK-BR-3: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051430: AB_2681483" "unprognostic (6.34e-2)" "unprognostic (5.14e-2)" "unprognostic (5.55e-2)" "unprognostic (2.81e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" "unprognostic (5.36e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-1)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "prognostic favorable (3.20e-4)" 29.5 6.8 19.2 45.4 50.5 72.7 25.2 43.4 33.5 11.3 5.2 23.5 21.7 7.6 1.0 25.4 14.1 9.7 35.9 19.3 26.4 20.6 9.1 40.3 69.7 59.3 49.7 3.8 14.6 3.1 5.6 8.8 55.9 20.2 6.6 0.6 29.3 7.9 3.5 17.9 50.6 3.5 35.8 110.5 14.6 2.6 48.4 26.3 12.9 1.8 32.4 14.6 18.4 81.9 17.9 14.0 7.5 6.0 0.0 0.0 15.2 0.0 0.0 0.2 0.2 25.2 19.2 19.7 23.7 0.0 6.3 31.0 1.0 5.9 0.0 2.0 11.3 41.3 4.2 31.0 1.9 38.3 67.0 1.1 16.2 0.0 1.3 0.2 14.7 9.2 108.7 73.3 0.0 36.1 18.9 65.4 5.9 32.9 4.9 8.4 0.6 58.9 11.4 65.1 1.9 4.9 5.7 121.0 33.2 9.7 68.7 57.6 5.2 0.0 8.7 0.1 0.3 57.6 27.3 13.2 0.0 60.4 1.0 17.7 11.6 23.2 56.2 38.3 49.0 28.5 41.7 46.2 18.6 21.7 36.5 39.6 15.3 35.8 63.5 5.7 38.0 33.5 19.2 50.5 43.4 33.5 19.3 26.4 59.3 49.7 55.9 35.8 48.4 81.9 43.8 41.7 29.6 8.1 69.5 11.1 21.0 22.3 7.4 3.2 17.4 6.5 14.7 10.0 41.5 16.5 0.0 1.2 79.8 25.0 0.0 41.2 0.3 5.1 1.6 19.7 9.1 28.4 0.2 23.1 26.4 4.6 10.2 8.0 40.5 0.7 23.6 2.2 67.0 1.7 0.2 14.0 40.7 66.2 29.9 1.2 9.6 44.7 14.2 20.6 62.0 7.5 85.5 1.5 50.8 40.5 53.7 1.2 62.6 31.5 20.3 2.0 20.3 1.8 13.1 4.6 13.5 0.5 2.2 8.4 10.2 3.7 83.7 2.5 30.3 37.4 TMCC1 KIAA0779 ENSG00000172765 "Transmembrane and coiled-coil domain family 1" O94876 3 129647792-129893606 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Alveolar cells type 1: 54.5;Astrocytes: 119.1;Excitatory neurons: 206.7;Inhibitory neurons: 201.5;Microglial cells: 127.4;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 9.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053894 Uncertain NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA053894: AB_2682295" "unprognostic (4.26e-2)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (2.60e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (7.75e-3)" "unprognostic (1.13e-1)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.77e-6)" "unprognostic (6.82e-3)" "unprognostic (2.90e-1)" "unprognostic (1.20e-1)" "unprognostic (2.32e-1)" 7.5 6.8 12.9 4.8 13.1 3.2 7.3 23.5 14.8 9.8 1.1 6.7 4.1 7.8 6.7 7.6 6.9 8.6 8.2 10.8 12.1 6.7 34.5 6.7 5.0 10.1 13.1 8.0 4.8 7.8 6.5 9.8 9.9 7.5 5.1 15.2 5.5 6.2 30.1 7.7 4.4 6.8 10.0 6.8 4.0 13.5 16.9 8.3 6.8 21.1 5.5 7.8 6.9 14.5 10.6 11.3 8.8 7.2 12.9 9.1 8.9 4.1 5.4 3.6 3.7 7.3 5.7 6.5 11.4 7.9 4.2 9.6 5.0 8.2 2.6 8.6 1.6 4.3 3.4 26.7 4.4 3.2 2.6 5.3 15.1 2.8 6.7 7.7 11.0 3.9 2.2 4.7 8.2 11.6 5.7 1.9 6.7 7.7 3.6 5.2 7.4 5.5 8.4 12.9 8.2 5.7 14.0 4.8 4.1 8.5 9.2 3.5 9.6 5.7 9.2 5.3 8.5 6.9 5.1 4.8 4.2 3.8 3.0 0.6 0.9 2.1 1.1 0.9 1.2 0.7 0.9 0.9 0.5 1.1 1.1 1.4 9.6 0.8 2.0 1.4 1.9 0.8 12.9 13.1 23.5 14.8 10.8 12.1 10.1 13.1 9.9 10.0 16.9 14.5 14.1 54.5 7.4 119.1 9.4 6.6 12.6 9.9 12.5 37.1 17.4 12.1 23.0 7.2 16.0 22.0 31.3 10.6 8.3 9.0 7.9 15.8 9.6 30.5 14.6 13.2 12.6 4.6 206.7 8.1 20.7 10.9 10.2 38.3 3.8 12.0 9.7 36.8 9.9 35.3 201.5 12.2 10.2 18.6 6.6 10.5 13.1 13.5 1.8 127.4 6.8 27.0 12.3 181.0 209.2 24.9 22.8 8.6 14.5 20.4 4.7 13.1 19.6 29.5 6.6 18.1 12.2 33.5 19.4 15.8 7.0 23.9 8.9 9.6 8.3 25.2 TMCC2 "FLJ38497, HUCEP11" ENSG00000133069 "Transmembrane and coiled-coil domain family 2" O75069 1 205227946-205285632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 88.1;brain: 47.3" "Cell type enriched" "Detected in many" 8 "Erythroid cells: 622.1" "Cancer enhanced" "Detected in many" "melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014254 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 6: Erythroid cells - Oxygen transport" "HPA014254: AB_1851326" "unprognostic (2.59e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (2.61e-2)" "unprognostic (4.18e-1)" "unprognostic (5.59e-2)" "unprognostic (2.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.53e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-5)" "unprognostic (3.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.99e-3)" "unprognostic (3.06e-2)" "unprognostic (4.01e-1)" "unprognostic (3.43e-3)" 1.4 2.6 15.2 0.4 24.2 88.1 0.9 18.7 47.3 1.8 0.0 2.5 0.3 1.6 0.0 0.7 2.0 0.3 3.6 25.2 16.1 1.4 0.7 3.1 0.3 38.5 26.1 3.1 0.5 3.1 5.0 5.3 41.0 1.0 0.1 8.5 0.9 0.3 3.5 1.7 0.9 0.5 17.3 16.0 0.9 2.0 25.5 0.7 1.3 1.5 0.2 1.2 1.6 33.6 1.9 0.9 1.7 3.8 0.7 0.2 0.9 2.4 1.0 2.3 1.8 0.3 0.2 1.8 0.4 0.6 6.3 3.2 1.1 0.5 0.7 5.7 4.2 7.5 0.5 0.1 0.3 0.3 3.5 0.4 0.1 1.2 0.0 2.0 0.3 1.7 4.0 2.4 0.9 0.1 0.0 0.9 4.1 0.0 5.2 2.8 4.3 9.1 0.4 0.1 32.0 4.3 0.2 0.0 8.0 1.5 0.7 0.4 0.8 1.5 2.5 3.9 2.7 4.9 2.1 1.2 1.3 0.6 9.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 15.2 24.2 18.7 47.3 25.2 16.1 38.5 26.1 41.0 17.3 25.5 33.6 1.9 0.0 0.0 6.2 0.4 1.0 0.4 1.2 0.0 34.4 0.2 0.0 4.6 0.0 0.3 1.8 10.4 0.1 0.3 0.0 0.0 1.6 1.5 3.7 0.8 2.5 3.5 622.1 7.9 0.0 0.2 1.0 0.0 1.9 0.0 7.4 3.9 0.0 0.9 40.4 10.1 0.1 0.0 0.6 6.1 0.8 1.2 13.1 3.6 2.8 7.8 17.7 0.0 2.5 73.0 0.2 0.0 0.4 0.8 0.1 0.0 0.2 0.9 43.2 0.0 1.8 2.8 1.1 4.8 0.4 0.9 0.0 0.7 0.8 0.1 0.1 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMCO3 "C13orf11, FLJ20623" ENSG00000150403 "Transmembrane and coiled-coil domains 3" Q6UWJ1 13 113491021-113554590 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 20.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039561, HPA048126" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA039561: AB_2676573, HPA048126: AB_2680276" "unprognostic (7.89e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (6.78e-2)" "unprognostic (7.88e-2)" "unprognostic (2.89e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (2.93e-2)" "unprognostic (9.44e-2)" "unprognostic (3.08e-3)" "unprognostic (2.76e-2)" "unprognostic (8.47e-3)" "unprognostic (3.70e-3)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (6.27e-3)" "prognostic unfavorable (4.10e-4)" 24.2 26.9 20.5 18.6 18.3 76.7 22.7 29.8 21.5 31.1 49.2 23.1 21.0 33.1 20.0 14.4 25.2 27.7 28.2 17.3 16.3 24.2 14.3 24.3 16.3 19.4 18.8 25.2 40.7 35.1 23.1 30.1 19.4 22.1 22.0 18.1 38.7 21.6 19.1 13.4 22.7 29.6 19.6 19.8 44.3 16.1 19.6 12.4 10.7 15.2 13.1 19.6 18.9 21.2 97.8 32.6 46.3 32.0 93.1 136.4 25.0 105.0 99.6 45.1 45.3 35.7 41.9 23.1 25.9 115.7 61.7 38.5 24.8 38.0 70.0 48.0 25.1 20.9 52.2 36.0 87.9 34.3 41.7 112.0 88.5 33.9 68.9 116.7 74.5 14.3 30.3 31.6 79.6 17.5 18.0 20.6 23.2 46.5 50.9 22.4 28.0 16.7 74.3 12.6 40.4 33.5 32.3 70.3 33.6 65.3 41.5 64.6 117.4 50.3 53.5 36.9 44.8 39.2 23.9 14.8 167.2 17.8 24.6 3.1 8.3 8.5 1.3 5.6 1.5 3.1 1.5 2.0 6.0 1.8 1.7 1.7 20.2 5.0 11.3 1.3 1.5 2.7 20.5 18.3 29.8 21.5 17.3 16.3 19.4 18.8 19.4 19.6 19.6 21.2 34.3 12.8 15.1 21.5 12.5 9.8 37.2 25.8 21.6 16.4 39.2 17.5 20.3 24.3 27.8 25.8 14.6 21.6 13.5 37.1 5.9 46.8 14.6 28.2 39.2 31.3 34.2 23.5 42.9 37.4 53.8 35.0 39.3 28.6 26.6 18.4 35.0 12.4 19.1 21.9 41.0 69.2 12.2 31.3 18.8 37.1 36.7 24.5 17.8 12.2 31.4 25.9 17.5 24.6 31.9 52.6 28.2 47.8 19.2 64.0 20.0 11.2 45.2 19.0 6.6 26.2 31.9 17.6 12.2 15.9 7.1 13.0 11.8 34.4 17.7 31.3 TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.3;prostate: 36.6;seminal vesicle: 13.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 416.1;Inhibitory neurons: 382.0;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 1337.5" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 36.9;LHCN-M2: 107.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" NA NA "Cluster 65: Brain - Ion transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" 0.3 2.3 30.2 0.1 25.8 0.0 0.3 16.0 26.6 0.1 5.8 0.9 0.6 0.0 8.1 1.2 0.1 1.7 1.8 28.5 26.9 0.0 0.0 0.1 0.0 21.5 23.5 0.2 0.0 0.0 0.3 0.0 22.4 36.6 1.5 3.3 0.1 13.3 0.3 0.2 0.6 0.1 16.6 0.0 0.9 0.7 26.3 0.0 0.2 0.6 0.1 0.8 0.5 33.3 0.0 0.9 36.9 0.0 5.6 5.8 0.1 0.1 0.7 1.8 2.2 0.0 0.0 0.0 0.0 10.3 4.5 0.0 2.3 0.0 7.1 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 15.6 0.0 2.0 10.8 9.0 0.1 0.0 0.0 0.0 107.1 0.0 0.0 0.1 2.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.2 2.8 0.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 25.8 16.0 26.6 28.5 26.9 21.5 23.5 22.4 16.6 26.3 33.3 0.1 0.0 0.0 11.8 0.0 0.1 0.1 0.0 0.0 16.6 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 416.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.6 382.0 0.5 0.0 0.0 0.7 2.3 26.4 0.0 0.0 11.2 0.0 0.6 0.0 210.6 1337.5 0.0 0.0 8.6 0.0 5.7 0.1 0.0 0.0 1.6 6.6 24.6 0.6 1.2 2.6 0.3 0.3 0.0 0.4 0.0 0.0 0.1 TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.8;Endothelial cells: 25.5;Fibroblasts: 40.7;Leydig cells: 40.7;Peritubular cells: 52.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 28.9;ASC TERT1: 19.5;HHSteC: 44.8;HSkMC: 20.6;U-87 MG: 13.9;WM-115: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" 40.8 5.0 5.4 3.2 5.5 0.0 27.6 4.3 9.0 15.8 6.0 14.5 6.7 3.6 36.6 6.5 8.0 7.3 18.7 5.1 7.0 1.9 7.0 192.5 1.2 5.5 7.0 26.5 2.3 0.8 11.2 54.1 6.0 10.3 11.6 0.4 8.0 24.7 9.7 4.6 13.2 5.5 4.6 6.9 30.2 2.7 8.1 1.1 7.5 14.1 0.6 11.1 8.2 4.7 0.0 0.0 5.9 0.0 28.9 19.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 44.8 0.0 0.0 20.6 0.0 1.4 0.1 0.2 0.0 0.3 1.0 0.1 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 8.7 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 1.9 3.9 0.0 0.8 0.0 0.1 13.9 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.5 4.3 9.0 5.1 7.0 5.5 7.0 6.0 4.6 8.1 4.7 57.8 0.0 3.6 2.3 0.1 2.5 0.3 0.0 1.2 0.7 0.4 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.1 4.0 25.5 0.0 0.0 0.1 0.0 0.0 40.7 1.5 0.2 1.3 0.1 7.1 15.2 0.1 0.0 1.6 0.0 0.0 0.0 4.9 0.5 40.7 0.2 7.2 1.9 0.0 0.0 0.0 17.1 0.0 0.1 0.0 52.6 0.0 0.1 0.0 3.4 0.0 0.1 32.9 10.3 15.1 0.1 0.2 0.7 2.6 0.1 0.5 0.3 0.0 0.3 TMEM106C MGC5576 ENSG00000134291 "Transmembrane protein 106C" Q9BVX2 12 47963569-47968878 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 244.8;Muller glia cells: 268.4;Paneth cells: 208.3;Proximal enterocytes: 385.7;Undifferentiated cells: 220.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 876.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047204 Enhanced NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA047204: AB_2679982" "unprognostic (1.63e-2)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.27e-8)" "unprognostic (1.05e-1)" "unprognostic (1.90e-2)" "unprognostic (1.52e-3)" "unprognostic (3.60e-1)" "unprognostic (7.29e-2)" "prognostic favorable (4.62e-4)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-2)" "unprognostic (1.83e-1)" 28.1 41.9 37.4 36.3 37.5 48.2 66.6 38.2 46.1 52.0 56.7 138.2 113.2 35.8 135.8 42.0 48.5 45.5 58.9 39.7 42.4 80.9 44.7 39.4 38.4 36.4 36.3 55.5 66.5 146.2 62.9 73.4 37.1 41.0 145.3 121.7 59.7 51.7 26.5 37.4 120.1 55.3 35.5 78.1 53.5 40.0 43.4 55.9 49.3 34.3 46.8 28.9 32.8 33.7 243.9 166.4 151.7 167.7 68.5 50.0 143.2 133.6 191.0 238.5 203.8 250.2 243.3 212.2 182.9 147.6 221.8 162.1 239.2 146.1 226.6 203.8 229.1 163.7 217.2 101.7 52.4 172.6 117.9 34.4 98.4 217.8 114.2 163.4 154.2 224.0 113.4 235.6 169.6 174.4 248.2 75.5 27.0 258.7 226.5 217.9 195.9 180.9 127.2 183.2 100.9 120.5 206.8 138.5 142.4 78.4 503.5 136.9 38.3 99.8 168.9 145.0 240.9 130.8 228.9 240.1 127.3 876.5 97.9 39.3 8.8 23.9 44.4 8.6 54.9 36.9 42.8 46.5 12.5 30.8 39.7 44.0 7.6 19.6 10.4 1.9 66.4 41.0 37.4 37.5 38.2 46.1 39.7 42.4 36.4 36.3 37.1 35.5 43.4 33.7 14.5 32.1 20.7 6.8 26.5 47.9 39.2 45.8 36.5 30.2 54.9 78.7 39.1 61.5 21.9 35.0 18.8 75.3 17.7 244.8 86.1 63.8 2.8 35.7 5.7 17.3 36.0 49.2 14.1 45.1 32.8 45.4 37.2 18.6 10.8 86.3 55.0 19.6 54.3 30.3 13.0 150.8 101.7 16.4 20.7 6.8 32.6 21.5 21.4 8.4 10.1 268.4 27.8 4.5 1.2 35.5 208.3 41.3 72.5 22.6 385.7 82.2 11.5 47.2 13.1 46.4 36.9 52.8 36.0 55.4 40.9 14.9 31.5 35.0 220.5 39.4 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM114 ENSG00000232258 "Transmembrane protein 114" B3SHH9 16 8537605-8590193 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "seminal vesicle: 19.6" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hypothalamus: 6.6" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.72e-5)" "unprognostic (2.26e-1)" "unprognostic (3.98e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.62e-1)" "unprognostic (2.21e-1)" 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.6 0.0 2.9 0.1 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 3.1 1.1 1.7 2.9 0.3 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM116 FLJ90167 ENSG00000198270 "Transmembrane protein 116" Q8NCL8 12 111931282-112013185 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "parathyroid gland: 59.7" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "T-cells: 19.3" "Cell line enhanced" "Detected in many" "RT4: 33.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040720 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Microtubules Nucleoplasm "HPA040720: AB_10795623" "unprognostic (8.91e-2)" "unprognostic (1.95e-3)" "unprognostic (1.18e-2)" "unprognostic (1.71e-1)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" "unprognostic (2.93e-2)" "unprognostic (6.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.34e-1)" "unprognostic (3.27e-3)" "unprognostic (9.12e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.41e-1)" "unprognostic (1.33e-1)" "unprognostic (2.85e-2)" "unprognostic (3.19e-3)" 3.8 8.8 7.0 2.2 7.8 1.2 11.4 9.2 8.4 6.0 27.5 4.2 11.1 2.7 7.1 4.2 4.9 6.8 26.3 6.4 6.5 30.8 12.3 8.5 4.5 7.2 7.5 5.2 4.2 59.7 6.5 2.9 7.2 3.9 3.7 7.0 13.3 5.9 6.6 11.1 6.3 2.1 6.9 3.4 10.2 27.1 7.5 5.4 6.3 5.8 6.8 7.4 3.2 8.5 6.2 6.4 8.9 9.7 8.3 6.6 6.0 5.1 7.5 6.1 6.6 4.6 5.1 6.9 2.9 3.5 7.6 5.9 4.8 5.1 5.4 17.1 4.1 4.4 5.4 5.1 13.2 1.6 0.7 7.8 8.5 7.7 13.5 6.7 2.2 13.2 8.7 5.0 6.5 9.4 2.3 14.2 10.6 14.5 3.9 7.0 3.8 12.2 18.9 33.1 8.1 5.6 5.3 4.4 8.3 11.7 16.0 22.9 1.6 5.8 1.8 5.1 2.2 6.5 12.1 6.6 7.9 5.5 8.0 1.1 2.6 4.5 8.1 4.5 6.8 2.9 18.5 15.6 2.9 3.6 9.6 10.8 0.4 2.4 3.5 4.2 19.3 4.0 7.0 7.8 9.2 8.4 6.4 6.5 7.2 7.5 7.2 6.9 7.5 8.5 4.0 3.2 18.5 17.3 6.2 5.5 6.2 8.8 7.4 11.2 14.0 12.8 21.7 7.2 10.1 29.5 16.7 18.6 10.2 5.7 23.5 4.2 67.8 7.0 4.3 3.5 0.0 3.4 28.3 4.0 5.9 5.9 7.7 3.7 5.7 7.0 2.2 5.4 5.1 10.1 25.6 4.6 24.4 4.1 4.5 33.5 9.3 3.9 7.2 7.5 3.6 13.4 11.3 13.0 33.3 2.7 3.2 4.9 5.5 4.2 20.9 10.3 18.6 17.3 6.6 6.5 6.6 123.5 37.4 6.2 5.4 40.1 17.4 7.0 6.0 7.6 TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 220.2;Inhibitory neurons: 190.3;Microglial cells: 80.6;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046223: AB_10960636" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "unprognostic (4.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (2.89e-1)" "unprognostic (6.26e-2)" "unprognostic (1.99e-3)" "unprognostic (1.74e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (9.20e-3)" "unprognostic (3.80e-1)" 1.8 1.9 0.9 1.2 1.4 0.1 2.7 1.5 2.1 3.8 8.8 3.4 6.0 4.0 2.6 5.8 2.3 3.5 4.2 1.3 1.3 2.2 2.1 1.1 1.4 2.4 1.5 2.5 3.7 4.1 1.7 3.0 2.8 3.5 3.5 2.3 2.1 5.2 3.3 4.0 4.2 4.0 1.4 0.7 2.1 2.4 1.3 0.9 2.3 3.3 2.3 4.1 3.8 2.6 1.2 0.4 4.0 6.7 4.5 9.6 0.1 12.6 6.2 2.3 2.7 10.0 4.3 4.5 0.9 9.0 0.6 6.4 2.6 2.8 1.7 1.9 7.4 1.2 2.5 4.0 1.3 1.8 4.7 5.0 9.9 1.3 0.7 9.2 0.4 0.5 2.2 1.9 4.4 1.1 0.0 1.1 0.8 0.0 2.4 3.0 4.5 1.8 4.5 2.7 0.6 6.1 4.8 1.5 10.2 1.6 0.3 4.7 1.5 3.4 1.1 1.8 3.3 3.4 3.9 2.6 1.7 2.0 1.2 0.0 0.0 0.0 1.2 0.0 1.7 1.0 0.3 1.2 0.0 0.9 0.5 0.6 0.0 0.4 0.0 0.1 0.2 0.4 0.9 1.4 1.5 2.1 1.3 1.3 2.4 1.5 2.8 1.4 1.3 2.6 3.2 0.0 1.3 65.6 8.4 6.5 4.8 3.4 9.6 3.9 2.4 2.8 5.4 2.8 2.5 7.3 4.2 15.0 2.8 6.9 3.9 2.8 25.8 3.9 5.5 2.1 0.0 1.7 220.2 3.0 2.7 3.8 18.3 6.0 2.5 6.0 4.2 2.7 5.6 5.0 190.3 4.2 12.2 3.8 2.5 9.5 6.2 2.1 12.4 80.6 0.1 3.4 3.1 123.1 152.4 2.5 19.2 6.4 11.2 2.1 13.8 1.3 2.7 5.2 0.0 2.2 3.8 1.4 5.5 17.7 12.1 11.5 5.1 2.3 5.0 4.9 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM126A "DKFZp586C1924, OPA7" ENSG00000171202 "Transmembrane protein 126A" Q9H061 11 85647967-85656547 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046648 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA046648: AB_2679737" "unprognostic (3.79e-2)" "unprognostic (4.75e-3)" "unprognostic (2.08e-3)" "unprognostic (1.08e-3)" "unprognostic (2.08e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.60e-5)" "unprognostic (8.25e-2)" "unprognostic (6.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.02e-2)" "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (6.94e-2)" "unprognostic (2.17e-1)" 31.9 28.0 40.3 23.1 41.5 43.8 33.5 41.4 52.3 21.8 39.5 28.0 32.6 20.0 31.2 27.2 19.8 19.9 82.1 41.4 42.3 33.1 49.0 20.5 27.3 40.7 40.6 21.0 33.9 26.3 22.2 22.8 41.5 23.5 29.3 23.9 31.3 19.5 81.6 19.4 26.0 27.6 41.1 21.0 32.8 38.5 41.4 24.2 26.6 98.7 27.8 30.5 20.1 42.4 46.7 53.2 50.9 33.0 67.2 66.7 38.0 55.9 60.1 82.3 77.6 65.9 67.5 25.4 61.3 69.2 32.0 48.9 53.8 59.5 70.7 72.5 31.0 72.5 56.9 73.7 82.4 89.0 54.8 58.0 65.8 73.1 78.0 43.5 71.6 72.2 51.1 39.0 86.2 57.5 48.6 112.3 48.1 175.1 68.4 48.3 49.5 79.2 54.5 57.0 34.3 34.7 49.4 72.9 44.7 44.5 88.1 64.4 42.8 70.4 52.7 134.6 65.3 27.5 54.4 70.4 37.0 63.6 85.2 6.6 23.9 11.6 21.2 28.1 26.0 29.8 26.4 23.8 32.9 27.3 24.4 24.1 1.9 15.1 23.4 24.7 26.4 18.7 40.3 41.5 41.4 52.3 41.4 42.3 40.7 40.6 41.5 41.1 41.4 42.4 40.5 28.9 24.3 12.7 39.6 31.7 55.3 87.9 29.6 14.8 45.8 62.1 110.8 28.6 57.5 38.6 6.2 67.8 38.5 23.6 146.8 51.0 147.8 26.8 32.8 36.7 21.7 46.1 8.6 93.2 73.3 40.8 23.4 24.2 37.4 33.6 26.7 68.5 94.6 8.4 9.0 46.6 40.7 54.4 43.3 80.6 29.5 48.4 33.8 5.6 66.3 35.1 38.1 8.5 11.8 64.5 34.8 26.7 45.4 73.4 61.8 109.4 39.7 21.9 19.7 40.0 40.9 119.0 57.9 49.4 42.1 52.9 42.1 42.2 57.1 71.2 TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.15e-3)" "unprognostic (2.67e-1)" "unprognostic (1.72e-2)" "unprognostic (6.51e-2)" "unprognostic (5.82e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (6.73e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (7.50e-2)" "unprognostic (2.17e-1)" "prognostic favorable (6.69e-5)" "unprognostic (3.59e-1)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" 29.3 34.6 25.9 28.5 24.6 53.0 25.6 20.1 30.6 30.7 15.7 34.4 32.6 30.0 21.4 40.0 25.2 32.3 67.8 26.7 23.6 29.5 35.4 31.6 21.4 24.5 26.3 31.9 28.5 73.1 29.4 26.8 24.5 26.1 30.5 27.6 39.7 42.4 25.9 33.0 34.7 35.1 21.1 34.7 27.8 10.2 29.7 19.1 26.2 30.6 25.4 38.6 27.8 21.9 28.8 38.0 19.9 30.7 86.0 43.3 36.7 36.9 65.9 38.6 35.2 37.9 40.0 17.9 52.8 73.3 67.8 45.1 23.1 34.2 26.8 36.1 17.8 31.2 17.6 37.5 55.4 26.7 54.0 52.7 48.0 48.0 35.3 51.4 44.5 12.1 19.5 37.6 39.8 32.8 17.6 16.8 27.3 33.9 40.4 16.4 25.0 26.9 42.9 48.7 22.3 23.4 27.1 63.8 31.3 40.2 23.6 28.2 52.5 63.9 36.2 55.9 25.8 28.2 29.6 14.1 42.6 30.9 34.7 3.9 6.3 8.2 2.8 6.6 3.0 1.8 2.1 3.0 4.3 1.9 1.6 2.2 14.3 1.5 5.3 2.5 1.6 3.2 25.9 24.6 20.1 30.6 26.7 23.6 24.5 26.3 24.5 21.1 29.7 21.9 24.8 19.2 15.3 7.2 13.4 17.2 16.6 14.5 12.0 22.1 20.0 12.8 39.6 22.8 20.2 27.6 27.1 11.4 19.3 88.2 15.6 29.7 5.2 16.4 15.1 23.1 16.3 9.0 12.9 34.8 13.1 16.7 14.8 28.8 13.9 13.6 29.6 35.7 37.7 21.9 15.7 26.7 12.2 59.8 33.2 5.8 13.7 34.0 16.0 5.6 41.9 7.8 15.5 8.0 6.6 41.0 35.1 17.0 13.0 23.1 43.9 13.3 15.7 16.9 6.6 18.5 19.4 9.1 2.9 12.6 23.3 24.2 14.3 15.9 18.6 34.1 TMEM129 D4S2561E ENSG00000168936 "Transmembrane protein 129, E3 ubiquitin ligase" A0AVI4 4 1715952-1721358 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.12e-1)" "unprognostic (2.85e-1)" "unprognostic (4.04e-2)" "unprognostic (1.22e-3)" "unprognostic (7.35e-3)" "unprognostic (4.82e-2)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (2.51e-3)" "unprognostic (2.81e-1)" "prognostic favorable (9.64e-8)" "unprognostic (1.47e-1)" "unprognostic (6.49e-2)" "unprognostic (3.08e-1)" "unprognostic (2.36e-3)" 20.8 33.7 30.2 11.0 31.2 6.1 20.6 30.2 30.7 23.7 37.1 34.4 22.0 27.8 10.1 25.0 26.7 11.8 38.6 27.9 28.1 41.2 46.9 21.7 13.0 35.0 32.6 25.8 36.9 33.2 43.0 10.2 29.5 29.6 8.5 6.4 32.9 19.1 30.9 20.3 26.1 9.5 33.2 25.9 31.6 15.4 32.2 8.1 35.5 18.7 8.2 27.0 19.8 30.1 16.1 18.4 15.0 22.4 27.0 15.7 17.3 12.7 20.4 13.0 13.9 13.6 38.8 20.9 14.9 13.7 23.1 15.8 7.7 16.2 2.2 14.5 23.1 11.9 13.9 17.5 22.0 16.4 19.9 26.1 34.2 7.1 6.5 30.1 20.3 19.4 13.2 15.1 12.4 12.6 22.4 26.5 23.3 17.6 22.4 14.3 7.9 26.0 32.6 17.6 34.7 21.4 10.9 19.0 17.3 5.3 39.3 7.5 14.0 15.0 11.3 13.3 12.5 37.7 12.1 10.0 17.3 22.2 16.4 0.1 1.7 0.0 1.6 1.1 1.4 0.7 1.4 1.2 1.6 0.9 1.0 0.7 0.3 1.0 1.2 3.7 0.7 1.1 30.2 31.2 30.2 30.7 27.9 28.1 35.0 32.6 29.5 33.2 32.2 30.1 13.2 22.4 9.3 17.0 11.4 5.1 15.2 9.6 13.6 27.2 15.4 13.0 12.9 18.6 6.6 23.9 6.2 20.9 26.8 28.8 25.4 20.4 1.1 7.9 8.2 12.4 13.1 8.6 7.3 19.6 7.8 17.4 12.8 8.4 10.2 14.7 15.4 19.9 17.9 25.2 9.0 26.5 14.2 11.7 4.9 3.1 30.4 8.7 10.6 13.1 7.2 39.6 25.7 8.0 11.9 14.1 14.9 36.1 13.1 16.8 24.0 18.4 7.9 19.7 13.1 21.9 17.1 7.1 5.6 13.7 9.5 5.5 12.1 22.7 33.8 11.3 TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Vesicles, Intermediate filaments" "HPA017678: AB_1858086, HPA017682: AB_1858087" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (7.42e-2)" "unprognostic (8.58e-2)" "unprognostic (4.18e-2)" "unprognostic (7.59e-3)" "unprognostic (3.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.10e-3)" "unprognostic (5.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.77e-1)" 12.1 12.2 7.2 20.7 7.5 17.5 10.6 7.2 7.6 18.8 9.3 25.8 18.5 16.3 8.5 14.3 15.3 15.8 13.0 7.4 5.5 12.1 13.5 12.4 25.4 6.1 7.5 16.3 19.0 27.5 11.1 18.3 6.1 16.6 23.2 11.4 13.4 11.5 24.4 24.1 19.4 16.5 6.6 18.4 26.2 14.7 10.3 18.4 12.8 22.3 23.1 14.1 10.4 8.6 26.1 15.7 28.8 21.0 29.6 35.8 31.4 37.8 36.5 18.9 22.7 20.3 36.8 41.3 20.4 39.3 32.2 18.4 30.5 50.5 28.0 29.4 19.8 30.0 10.6 29.3 33.4 28.2 38.6 34.4 20.2 33.7 34.7 32.0 23.5 19.8 18.1 42.8 58.2 15.7 20.6 17.9 15.8 20.2 33.4 29.7 18.3 18.3 19.3 30.7 32.3 15.7 24.4 16.7 23.2 30.7 14.0 25.8 28.1 49.1 22.4 23.9 14.7 18.1 26.8 20.6 38.5 24.3 33.9 3.7 1.3 3.6 1.7 1.6 1.9 2.1 1.5 1.7 1.7 1.9 1.7 2.3 0.9 2.5 1.6 2.4 1.0 1.0 7.2 7.5 7.2 7.6 7.4 5.5 6.1 7.5 6.1 6.6 10.3 8.6 29.4 16.0 27.9 90.1 41.2 19.8 17.7 16.3 24.5 28.3 17.3 16.0 34.7 15.7 23.4 20.2 22.9 15.4 33.1 62.2 3.9 9.7 14.4 88.9 33.9 19.3 30.1 23.5 113.1 24.0 12.7 23.5 60.1 86.8 23.5 21.3 22.9 26.0 24.5 25.2 99.7 45.6 10.2 29.2 18.5 20.1 20.8 35.8 12.4 87.1 47.0 14.1 9.2 92.5 129.8 18.1 40.1 19.2 36.3 17.9 27.4 7.0 38.2 19.3 13.1 31.9 24.9 21.2 26.0 25.0 25.6 13.5 22.4 28.0 36.6 16.0 TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" 12.6 24.3 22.5 8.6 23.2 4.7 14.8 21.2 29.9 15.6 19.9 14.0 8.3 9.6 11.0 55.5 10.2 6.5 46.8 21.6 22.2 25.2 33.9 11.2 11.9 22.8 22.6 8.6 42.9 7.9 8.7 5.3 22.4 25.7 4.5 2.8 20.6 7.3 57.4 57.5 14.5 4.4 22.7 16.2 22.4 26.5 22.9 6.6 13.5 26.0 8.8 15.9 25.4 22.5 12.3 4.6 6.5 14.0 4.3 7.3 7.2 2.5 4.6 2.9 1.2 5.8 14.3 11.7 27.2 6.2 9.2 10.0 2.9 10.7 1.8 11.3 4.9 2.2 4.5 5.9 6.6 2.3 3.2 7.3 13.4 2.3 7.7 12.7 3.0 7.9 3.0 6.6 6.3 29.0 13.3 8.6 11.0 20.4 16.3 6.5 3.8 38.5 11.3 12.5 6.0 13.3 9.1 14.2 28.6 4.4 34.5 2.3 5.8 10.4 9.0 12.5 3.3 27.8 19.4 8.2 15.6 3.0 8.5 58.2 54.3 98.5 71.4 132.7 78.8 203.7 84.2 80.6 66.6 195.7 85.6 80.6 25.7 90.2 176.0 87.3 123.9 73.3 22.5 23.2 21.2 29.9 21.6 22.2 22.8 22.6 22.4 22.7 22.9 22.5 43.3 16.0 41.5 11.8 83.0 90.0 87.7 177.7 99.0 29.3 139.9 173.4 53.4 60.1 93.5 68.0 10.4 69.5 46.5 64.7 133.1 95.0 50.2 53.0 35.3 36.6 71.4 22.3 9.4 126.0 147.9 31.3 120.3 73.4 23.4 52.5 29.3 69.6 84.0 11.8 8.2 100.3 97.6 43.6 49.3 46.2 20.8 49.0 110.3 2.8 61.2 39.5 63.8 9.5 14.1 189.9 81.7 24.8 47.2 142.6 150.8 148.9 75.0 29.5 6.6 24.4 45.9 105.8 80.1 185.1 180.1 72.8 53.3 37.6 73.5 152.2 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61362344-61369509 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 194.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042373 Approved Approved Microtubules NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA042373: AB_10793880" "unprognostic (1.30e-1)" "unprognostic (4.69e-3)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.15e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.49e-1)" "unprognostic (4.46e-1)" 13.8 40.6 8.4 11.5 8.5 18.1 14.3 10.3 9.7 16.3 10.0 13.4 10.8 17.5 25.9 10.8 17.3 11.6 9.1 8.7 9.1 17.9 22.2 15.3 18.0 9.0 11.0 23.7 13.9 18.4 12.6 14.9 8.6 17.1 18.7 50.7 11.1 13.8 6.8 18.6 15.9 18.6 9.0 18.4 13.5 12.5 8.9 14.0 13.5 8.5 22.8 17.8 13.3 9.5 16.3 35.5 14.0 20.3 48.9 20.1 16.5 24.9 30.7 36.2 32.8 17.7 24.6 14.0 21.0 29.7 56.5 30.2 26.0 31.0 39.8 18.0 14.4 10.1 28.7 21.0 35.0 21.8 26.3 32.4 47.7 60.5 39.4 13.5 31.4 16.7 29.8 23.0 60.1 45.4 17.3 21.6 22.8 28.2 34.5 11.9 10.3 30.4 32.3 39.6 14.9 11.1 31.7 30.4 34.2 12.8 47.3 19.0 18.7 45.2 18.7 31.5 24.7 24.0 24.6 13.6 23.7 26.5 24.0 41.7 26.0 26.5 23.1 26.6 25.3 26.1 21.7 22.3 15.9 24.1 24.0 21.4 5.3 27.8 18.2 28.0 30.2 24.1 8.4 8.5 10.3 9.7 8.7 9.1 9.0 11.0 8.6 9.0 8.9 9.5 12.6 16.0 23.2 16.0 23.1 19.9 16.1 49.8 25.0 28.9 15.7 17.1 4.2 4.3 26.2 20.2 81.3 54.8 27.3 13.9 15.6 17.1 21.7 22.0 16.6 18.7 9.6 22.1 12.5 16.0 39.9 20.5 9.2 7.0 37.3 17.8 13.6 16.3 45.7 15.2 12.1 11.6 16.2 15.6 10.7 7.6 31.7 35.6 37.4 3.7 25.5 25.9 36.0 10.1 8.1 18.6 11.5 28.6 18.1 22.1 26.7 20.8 59.6 194.1 0.0 15.3 14.3 24.9 16.2 16.3 20.5 27.5 23.3 56.9 14.3 12.9 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM143 FLJ10922 ENSG00000161558 "Transmembrane protein 143" Q96AN5 19 48332356-48364059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 43.6;skeletal muscle: 95.5;tongue: 61.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014476, HPA058645" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "HPA014476: AB_1858092, HPA058645: " "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (5.23e-2)" "unprognostic (2.50e-1)" "unprognostic (5.94e-2)" "unprognostic (2.11e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (4.08e-1)" "unprognostic (2.25e-1)" "unprognostic (7.29e-2)" "unprognostic (9.82e-2)" "prognostic favorable (1.53e-7)" "unprognostic (5.46e-2)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-1)" 6.5 9.0 5.2 2.6 6.0 2.7 5.2 5.3 6.8 4.9 4.3 7.2 4.5 4.3 2.5 4.6 4.5 3.2 43.6 5.2 5.4 10.4 18.1 4.3 3.7 5.5 5.5 4.7 5.7 3.7 5.1 2.7 5.5 5.3 2.7 3.3 5.6 2.6 95.5 5.8 6.8 2.2 4.7 7.7 6.8 4.2 5.7 6.2 6.4 61.2 2.3 6.2 4.3 5.9 4.6 7.4 2.3 4.2 4.5 6.3 4.7 4.2 2.5 2.9 3.7 6.3 5.9 8.6 7.5 2.8 1.4 5.2 2.3 3.0 1.6 10.6 5.2 5.2 6.3 10.1 3.6 4.1 4.8 5.8 3.7 1.5 3.7 3.3 2.4 12.9 3.8 12.5 3.1 2.6 5.9 14.8 2.9 8.7 2.5 8.6 1.4 14.2 3.9 3.4 8.6 8.5 2.5 3.1 2.1 2.6 4.4 2.9 2.9 3.5 3.9 2.6 1.6 24.3 8.2 6.5 2.9 5.4 2.8 1.9 1.2 1.4 2.2 0.7 2.7 2.1 1.7 2.1 1.5 1.5 2.6 1.5 1.0 3.4 1.2 0.6 1.3 1.3 5.2 6.0 5.3 6.8 5.2 5.4 5.5 5.5 5.5 4.7 5.7 5.9 2.3 3.2 1.1 8.1 3.7 0.3 3.0 3.4 2.8 3.3 3.2 1.8 27.0 0.0 2.0 1.8 8.4 9.5 2.8 3.7 13.7 3.5 0.7 2.0 1.4 2.2 3.0 4.8 9.8 2.4 6.1 3.3 5.6 1.3 1.3 4.6 1.4 7.5 5.5 0.0 8.7 4.4 4.1 2.1 1.0 1.3 2.5 2.6 8.8 6.5 2.5 3.9 2.1 5.5 9.9 1.2 7.1 1.2 7.6 0.9 8.5 14.6 5.3 6.7 0.0 2.5 3.1 8.7 5.5 3.1 1.0 3.7 3.6 3.4 4.3 1.2 TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 418.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 994.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA063554: AB_2685039" "unprognostic (1.26e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-2)" "prognostic favorable (2.89e-4)" "unprognostic (2.90e-1)" "unprognostic (1.71e-5)" "unprognostic (8.27e-2)" "unprognostic (3.32e-1)" "unprognostic (2.21e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (9.34e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (3.88e-2)" "unprognostic (4.05e-2)" 8.6 12.9 91.0 3.6 235.8 3.1 15.4 164.3 134.4 7.6 15.3 14.4 29.4 6.1 15.6 5.4 6.8 12.5 14.9 101.1 122.5 3.8 3.2 6.3 2.3 204.2 158.6 13.5 7.4 4.6 1.3 6.5 201.8 9.0 15.9 0.6 5.9 10.9 2.8 3.4 20.7 7.1 133.8 4.0 11.2 27.0 163.9 1.9 16.9 2.6 1.6 6.6 2.6 418.0 4.7 12.1 0.2 2.6 8.6 11.8 36.5 1.9 3.9 1.7 2.8 15.1 17.8 0.0 2.8 0.6 10.0 2.2 5.1 16.7 2.4 0.0 5.5 8.5 3.0 13.5 2.8 10.7 2.3 8.9 20.0 7.0 3.0 0.5 9.7 1.7 5.5 0.2 12.8 5.1 0.0 0.0 3.2 15.1 2.9 0.0 0.0 0.4 4.2 12.3 1.9 0.0 0.5 19.6 4.2 7.1 12.6 2.4 1.8 3.9 2.7 0.7 2.1 0.0 1.1 0.9 5.4 1.4 3.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.3 2.2 0.0 0.3 91.0 235.8 164.3 134.4 101.1 122.5 204.2 158.6 201.8 133.8 163.9 418.0 2.9 9.6 9.1 53.2 0.3 3.1 7.7 5.2 2.8 0.9 12.4 10.7 12.7 12.8 8.4 0.0 0.0 13.7 1.5 36.6 0.0 15.4 231.8 14.5 8.6 4.8 4.9 3.0 10.9 13.3 6.5 4.4 14.8 24.5 4.5 14.6 4.6 1.2 29.0 0.0 12.5 21.4 8.2 20.8 5.0 98.2 10.5 12.9 3.6 12.2 10.6 1.3 0.0 5.5 994.4 9.0 18.9 9.1 0.2 3.5 44.1 6.4 8.8 0.2 0.0 8.5 2.6 3.0 2.2 5.8 5.1 8.8 0.9 6.8 18.6 6.4 TMEM14B MGC1223 ENSG00000137210 "Transmembrane protein 14B" Q9NUH8 6 10747759-10852753 "Predicted membrane proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.45e-3)" "unprognostic (6.80e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.51e-4)" "unprognostic (5.45e-1)" "unprognostic (2.58e-3)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "prognostic favorable (7.41e-4)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (8.24e-2)" "unprognostic (4.77e-2)" "unprognostic (4.83e-2)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" 78.4 101.1 58.2 45.0 60.6 186.3 74.8 62.9 81.2 51.8 77.6 60.3 53.7 46.5 78.0 47.4 72.0 48.7 132.8 59.8 60.6 81.9 91.0 45.2 70.9 61.1 59.3 50.1 64.3 77.3 40.3 41.5 60.5 65.5 58.8 151.6 86.1 44.1 146.5 46.0 59.2 42.6 61.0 42.2 64.4 27.5 60.4 78.6 128.1 141.5 57.5 52.2 41.4 63.6 376.2 155.9 72.9 106.7 80.0 102.8 106.4 77.9 136.6 163.8 193.2 153.8 171.8 130.8 187.1 93.1 375.9 81.8 65.5 135.1 253.4 89.3 89.6 107.9 123.1 235.2 120.0 163.2 102.1 83.6 76.7 174.6 174.9 92.3 91.6 120.1 267.2 54.1 135.0 134.7 144.4 182.0 110.1 198.6 118.9 120.1 97.1 304.9 198.7 91.7 117.9 88.0 95.7 188.6 251.3 139.0 132.3 145.0 91.7 120.0 150.0 82.3 268.6 128.4 289.4 175.7 98.5 92.4 190.1 178.1 112.1 161.2 86.1 109.8 121.5 121.7 120.7 100.1 136.3 114.7 130.3 111.5 64.4 117.0 122.3 168.6 141.0 154.9 58.2 60.6 62.9 81.2 59.8 60.6 61.1 59.3 60.5 61.0 60.4 63.6 103.2 80.1 77.2 21.5 95.4 82.0 92.1 169.9 90.5 85.5 157.9 206.8 141.4 144.4 113.8 88.3 60.5 177.1 89.7 94.1 365.9 183.3 18.9 190.4 73.2 83.5 80.5 399.9 19.9 220.9 183.0 97.0 68.3 101.9 82.4 90.2 70.6 156.3 210.0 107.7 21.2 143.2 130.2 121.0 132.6 53.5 96.3 110.1 120.9 9.4 265.8 239.0 52.5 17.1 18.1 261.3 102.5 75.2 102.5 145.8 142.0 309.5 247.6 196.1 26.3 95.6 92.8 46.5 129.9 103.9 100.7 105.9 99.4 133.3 164.3 109.0 TMEM151B "bA444E17.5, C6orf137, TMEM193" ENSG00000178233 "Transmembrane protein 151B" Q8IW70 6 44270450-44307506 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 53.7" "Group enriched" "Detected in some" 5 "Excitatory neurons: 27.0;Inhibitory neurons: 31.4" "Cancer enhanced" "Detected in single" "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055167 Uncertain NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055167: AB_2682723" "unprognostic (1.28e-3)" "unprognostic (6.25e-2)" "unprognostic (5.06e-2)" "unprognostic (7.02e-3)" "unprognostic (6.61e-2)" "unprognostic (1.22e-3)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-4)" "unprognostic (1.48e-1)" "unprognostic (4.56e-3)" "unprognostic (1.85e-1)" "unprognostic (9.15e-2)" "unprognostic (3.86e-2)" "unprognostic (1.66e-1)" 0.1 2.9 12.4 0.4 20.9 0.2 0.2 47.4 53.7 0.3 0.0 0.9 0.5 0.2 0.0 0.2 0.3 0.0 0.6 34.8 2.9 0.2 0.2 0.1 0.2 8.4 4.3 0.3 0.4 0.0 3.9 0.0 11.3 0.3 0.3 2.8 0.3 0.0 0.2 0.2 0.7 0.1 1.5 0.3 0.5 0.8 12.9 0.1 0.3 0.0 0.0 0.1 0.4 15.7 0.0 0.1 6.3 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.0 0.7 0.1 0.2 0.0 0.0 0.1 0.2 0.4 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.4 0.0 0.0 0.1 0.7 4.9 0.1 0.2 0.5 0.0 0.1 0.0 0.1 28.6 5.9 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.4 0.3 0.1 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 20.9 47.4 53.7 34.8 2.9 8.4 4.3 11.3 1.5 12.9 15.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 5.3 0.1 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.0 31.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.8 0.0 0.4 0.0 4.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM156 FLJ23235 ENSG00000121895 "Transmembrane protein 156" Q8N614 4 38966744-39032922 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in many" "B-cells: 99.8;Microglial cells: 68.4;NK-cells: 28.8;Plasma cells: 123.1;T-cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 74.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 39.6;GAMG: 29.6;HBEC3-KT: 84.8;hTERT-HME1: 64.0;NB-4: 35.2;PC-3: 37.3;U-698: 45.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.09e-4)" "unprognostic (7.36e-3)" "unprognostic (3.31e-3)" "unprognostic (4.17e-3)" "unprognostic (1.82e-1)" "unprognostic (1.01e-3)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.43e-1)" "unprognostic (9.45e-3)" "unprognostic (5.17e-2)" "unprognostic (8.73e-4)" "unprognostic (3.89e-1)" "unprognostic (1.74e-2)" "unprognostic (3.92e-4)" "unprognostic (9.06e-2)" 0.4 1.7 1.7 9.0 1.6 1.9 1.1 2.0 1.8 0.5 1.7 1.7 1.8 0.5 0.2 0.5 0.5 1.9 0.3 1.9 1.9 0.5 2.8 0.9 23.6 2.7 2.2 0.4 0.3 0.2 0.1 0.1 2.8 0.6 1.9 0.5 0.9 0.5 0.5 0.4 5.1 0.4 2.3 11.1 2.6 0.2 1.9 5.1 0.4 0.0 26.8 3.0 0.2 3.4 2.4 23.9 0.2 0.2 0.0 0.6 0.2 0.1 6.4 0.0 0.0 0.2 0.3 39.6 0.3 0.0 29.6 0.2 0.2 84.8 0.3 0.4 0.0 2.1 7.7 0.5 13.3 16.8 0.3 0.1 4.2 1.7 64.0 4.9 7.3 6.5 5.8 0.2 2.8 0.2 3.1 35.2 0.1 0.9 37.3 0.8 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.1 1.2 17.9 2.9 0.5 0.2 0.7 0.2 0.1 45.3 5.0 15.2 0.1 16.8 0.8 48.6 12.2 0.3 14.3 74.8 20.7 12.2 8.4 59.9 8.0 10.4 1.8 12.5 0.3 12.4 15.4 8.3 1.7 1.6 2.0 1.8 1.9 1.9 2.7 2.2 2.8 2.3 1.9 3.4 0.6 0.0 1.8 0.7 99.8 0.5 0.8 0.5 0.0 0.6 2.3 2.4 0.3 17.2 1.9 0.0 0.0 0.1 22.1 0.0 0.0 0.5 1.3 0.3 1.1 3.3 0.0 4.2 0.6 0.0 1.2 0.8 1.5 0.2 0.0 0.0 2.9 0.4 1.6 1.7 0.7 0.2 2.0 22.8 2.7 2.8 0.0 8.4 10.6 68.4 2.7 0.1 28.8 0.5 2.5 1.1 0.0 0.0 123.1 0.8 0.0 0.4 1.5 0.5 0.0 1.4 0.6 0.8 0.1 0.0 0.6 0.3 30.2 0.1 0.3 0.8 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM160 FLJ20512 ENSG00000130748 "Transmembrane protein 160" Q9NX00 19 47045909-47048624 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 168.4;NB-4: 231.7;PC-3: 104.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055904 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA055904: AB_2682965" "unprognostic (2.45e-3)" "unprognostic (1.69e-1)" "unprognostic (4.49e-1)" "unprognostic (1.09e-2)" "unprognostic (3.71e-1)" "unprognostic (7.39e-2)" "unprognostic (3.60e-1)" "unprognostic (3.20e-2)" "unprognostic (6.58e-2)" "unprognostic (2.86e-1)" "unprognostic (8.21e-3)" "unprognostic (3.76e-2)" "unprognostic (1.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.03e-1)" "unprognostic (1.86e-2)" "unprognostic (1.37e-2)" 15.1 18.0 33.8 5.3 26.5 5.6 13.8 14.3 40.0 14.6 14.1 13.9 3.7 16.2 1.0 20.1 12.4 0.5 23.0 33.7 18.3 24.2 25.5 15.3 4.2 29.4 23.3 9.1 18.0 2.3 12.4 1.9 28.8 10.9 1.3 1.7 15.6 1.4 28.6 18.6 13.8 1.3 17.0 19.6 16.6 11.4 24.6 2.3 19.2 2.5 2.2 14.8 12.7 28.0 37.5 12.9 7.6 9.7 2.1 2.2 17.8 19.5 3.3 6.3 6.7 6.2 12.9 36.7 33.4 2.3 5.4 26.7 5.1 4.4 3.5 31.6 168.4 37.5 11.1 11.0 1.3 26.0 55.0 2.0 2.6 3.7 1.4 4.6 4.6 23.2 34.3 10.6 3.2 9.9 30.5 231.7 19.3 12.2 104.7 54.9 17.3 22.5 5.9 6.0 20.2 35.8 22.3 15.8 22.6 10.7 8.3 17.1 21.2 6.0 32.9 13.1 20.1 46.8 48.5 28.6 8.9 26.8 8.8 28.3 41.0 62.9 27.9 30.9 18.9 41.6 44.3 51.0 25.8 50.0 42.7 28.0 3.3 22.3 28.1 45.4 46.2 15.6 33.8 26.5 14.3 40.0 33.7 18.3 29.4 23.3 28.8 17.0 24.6 28.0 52.1 9.6 12.9 7.8 74.8 57.9 63.9 93.0 38.7 47.9 80.7 78.7 21.0 77.2 48.6 119.5 18.8 28.3 98.6 200.5 158.5 122.0 95.4 45.7 33.3 49.1 104.0 46.7 17.1 179.7 95.5 49.4 58.1 45.6 57.3 60.2 56.7 96.1 152.9 20.2 18.1 120.2 95.6 138.2 99.8 255.3 48.7 89.7 94.3 4.7 194.0 106.6 161.7 11.6 13.8 155.9 164.3 52.6 87.1 61.7 207.7 247.6 33.1 31.7 32.9 38.0 63.9 32.8 33.7 66.5 81.8 14.2 87.5 61.1 120.8 84.8 TMEM161A "FLJ20422, FLJ39645" ENSG00000064545 "Transmembrane protein 161A" Q9NX61 19 19119169-19138513 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043365 Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA043365: AB_10796793" "unprognostic (4.31e-2)" "unprognostic (9.13e-2)" "unprognostic (2.34e-2)" "unprognostic (7.42e-3)" "unprognostic (6.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-2)" "unprognostic (3.51e-2)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (9.42e-2)" "unprognostic (2.46e-1)" "unprognostic (9.15e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.18e-1)" "unprognostic (2.79e-1)" "unprognostic (4.89e-3)" 13.0 22.5 4.5 4.4 4.6 5.4 13.6 4.8 6.9 19.8 7.1 15.8 3.5 21.7 1.5 14.8 17.6 5.4 17.7 4.3 4.3 15.3 25.9 12.3 4.8 6.9 4.6 17.7 15.7 13.7 8.2 3.3 5.4 14.3 3.7 2.5 14.9 7.1 50.7 16.9 11.2 6.3 4.4 10.4 14.7 6.3 5.4 5.8 19.5 13.2 4.8 14.3 15.9 5.9 28.9 19.3 12.6 20.1 24.8 17.1 12.8 13.4 12.8 16.4 20.1 17.5 30.8 26.4 57.9 9.4 11.3 23.9 20.6 29.3 11.4 9.9 47.6 10.0 10.6 24.0 30.9 9.1 14.7 26.9 23.9 15.6 25.9 14.9 17.9 30.5 31.6 27.2 12.5 33.8 19.5 24.7 9.9 37.1 19.6 33.4 9.4 44.8 13.0 13.0 13.0 13.6 20.2 20.1 15.7 9.1 17.1 24.0 7.6 13.3 5.3 34.4 21.1 27.8 14.9 16.1 13.9 22.5 20.7 1.3 6.1 1.4 8.2 5.3 6.7 4.3 7.5 6.2 8.4 5.6 8.8 6.3 1.1 5.4 7.1 19.4 11.4 4.1 4.5 4.6 4.8 6.9 4.3 4.3 6.9 4.6 5.4 4.4 5.4 5.9 15.7 6.4 18.3 5.5 9.5 6.1 15.1 27.1 14.8 15.7 13.4 15.4 8.7 20.0 18.3 11.0 10.4 19.8 14.8 6.5 7.9 20.5 1.2 8.8 14.1 11.3 5.4 6.7 10.9 12.9 15.1 14.6 14.8 9.5 15.9 15.1 9.7 25.3 16.3 16.8 11.4 10.0 10.2 9.5 4.1 1.5 11.8 7.5 12.4 5.6 6.8 15.8 8.2 4.5 8.4 11.9 7.5 17.7 13.6 14.9 12.5 29.1 11.8 14.5 13.1 13.5 14.3 8.7 8.4 12.4 8.7 12.3 11.4 33.8 19.3 10.0 TMEM165 "GDT1, TMPT27, TPARL" ENSG00000134851 "Transmembrane protein 165" Q9HC07 4 55395957-55453397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 1021.6;Urothelial cells: 601.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038299, HPA062424" Supported Enhanced "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA038299: AB_10675793, HPA062424: AB_2732682" "unprognostic (2.53e-2)" "unprognostic (1.08e-3)" "unprognostic (3.46e-3)" "unprognostic (7.07e-3)" "unprognostic (5.97e-2)" "unprognostic (9.84e-2)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (8.00e-3)" "unprognostic (1.55e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.18e-8)" "unprognostic (9.05e-2)" "unprognostic (8.96e-2)" "unprognostic (2.72e-1)" "unprognostic (2.18e-2)" 53.4 61.3 39.2 42.6 75.1 11.3 35.2 62.0 70.8 45.9 36.0 32.4 32.0 34.0 31.1 55.8 31.6 46.0 37.3 40.8 51.1 41.6 19.3 52.7 32.6 84.8 72.0 22.3 40.1 32.3 24.0 60.5 78.9 37.8 33.3 15.0 40.4 30.6 17.1 26.2 27.9 40.0 54.5 37.0 39.2 13.7 65.8 24.0 37.8 17.2 42.5 78.8 42.7 117.4 74.6 30.4 47.1 50.2 143.5 105.4 50.0 138.6 212.7 98.0 106.7 34.2 108.3 76.9 98.3 85.9 56.2 53.8 50.0 56.8 98.9 43.8 46.4 66.0 50.1 66.6 89.1 92.1 75.1 109.1 72.7 55.9 37.3 82.4 113.2 25.6 112.8 47.8 116.5 54.5 73.0 76.5 51.7 97.8 70.6 52.0 35.5 42.1 148.6 70.2 48.3 64.7 69.8 261.0 85.8 46.3 41.2 65.3 98.3 83.1 49.6 37.0 102.5 44.4 38.5 48.3 98.9 77.2 67.9 23.7 40.4 26.0 15.2 35.7 17.0 19.0 14.3 17.8 36.5 11.5 12.1 14.4 28.6 18.1 35.9 28.4 18.3 30.2 39.2 75.1 62.0 70.8 40.8 51.1 84.8 72.0 78.9 54.5 65.8 117.4 119.6 54.5 52.4 42.7 87.9 245.1 277.8 295.0 147.4 50.6 85.8 42.7 32.2 71.4 214.9 79.1 81.3 112.5 97.7 42.4 17.6 171.1 32.1 123.6 99.1 108.0 50.4 79.1 58.2 163.5 157.2 110.4 76.0 173.8 21.0 57.6 113.8 18.4 105.7 28.6 71.5 69.4 77.3 97.9 145.7 24.7 58.7 109.5 88.9 59.0 117.5 53.2 123.6 71.4 1021.6 248.0 48.6 63.6 117.1 239.3 51.3 50.0 125.2 91.9 98.6 92.2 129.0 37.8 24.6 169.4 268.8 80.6 81.6 90.6 61.6 601.6 TMEM167B "AD-020, C1orf119, FLJ90710" ENSG00000215717 "Transmembrane protein 167B" Q9NRX6 1 109090764-109096934 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (7.89e-2)" "unprognostic (3.28e-1)" "unprognostic (4.96e-2)" "prognostic favorable (8.86e-4)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-3)" "unprognostic (2.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (2.25e-1)" 31.7 35.5 29.9 24.2 30.3 53.7 33.1 30.0 34.4 32.4 29.6 27.7 23.2 30.9 31.6 24.0 25.4 25.6 35.9 30.1 30.5 33.3 33.0 28.4 26.2 29.1 30.2 29.7 25.7 45.1 15.9 33.8 29.6 36.9 29.8 31.3 30.3 27.9 21.3 28.9 23.7 30.6 31.3 28.3 32.4 23.4 30.9 25.1 41.7 25.9 27.7 27.2 16.3 33.0 36.1 6.5 23.4 32.3 47.8 47.0 20.9 54.2 49.7 30.0 27.8 13.7 13.4 24.0 30.1 55.9 17.8 17.4 15.1 24.1 43.0 37.4 11.4 22.4 8.7 18.8 53.6 43.6 36.6 38.8 64.7 27.9 46.7 40.8 26.5 30.8 28.5 33.9 33.0 22.2 33.0 28.1 17.7 31.0 33.1 20.5 37.1 19.0 38.6 22.5 16.6 17.0 26.2 38.0 53.0 20.8 23.7 32.0 25.2 30.6 30.8 67.0 26.6 34.0 20.6 23.7 51.7 44.7 65.0 38.1 20.7 35.4 13.3 23.8 19.1 14.4 17.6 17.0 19.1 13.5 17.8 17.8 45.4 17.5 30.8 11.7 17.9 19.9 29.9 30.3 30.0 34.4 30.1 30.5 29.1 30.2 29.6 31.3 30.9 33.0 29.6 32.1 31.4 10.7 30.1 30.5 29.4 25.7 16.5 30.1 28.2 17.9 34.0 22.8 28.6 18.4 12.5 42.1 38.7 20.0 19.6 26.7 19.1 16.2 25.2 30.7 20.9 25.9 11.5 30.1 44.3 32.3 23.0 27.1 32.3 21.7 27.8 21.7 39.1 25.2 12.5 25.2 24.4 36.8 42.8 17.0 28.9 38.8 26.6 6.5 56.3 36.0 24.7 12.5 16.4 29.3 19.7 25.2 16.8 39.8 25.9 29.6 19.7 30.1 0.0 21.7 26.8 28.9 28.2 26.0 35.7 63.1 32.9 20.4 19.1 51.5 TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;retina: 3.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.4;Cone photoreceptor cells: 22.9;Excitatory neurons: 13.1;Inhibitory neurons: 13.9;Oligodendrocyte precursor cells: 11.1;Oligodendrocytes: 9.3;Rod photoreceptor cells: 11.6" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.3;RPTEC TERT1: 12.3;SCLC-21H: 9.9;SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "HPA062462, HPA062797, HPA070657, HPA074877" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" Centrosome "HPA062462: AB_2732684, HPA062797: AB_2732690, HPA070657: AB_2686293, HPA074877: " "unprognostic (5.15e-2)" "unprognostic (2.93e-1)" "unprognostic (7.87e-3)" "unprognostic (4.69e-7)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.43e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (4.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" 0.5 1.0 1.4 1.0 3.0 0.3 0.2 1.5 2.6 0.7 0.0 0.4 0.7 0.3 0.7 0.2 1.0 0.8 0.4 2.3 2.1 1.8 1.7 0.6 1.0 2.6 2.1 0.3 0.3 0.1 0.8 0.1 2.8 0.4 0.3 3.4 0.2 0.3 0.3 0.5 0.6 0.4 1.0 1.0 0.2 0.3 1.7 1.0 2.6 0.3 0.7 0.2 0.1 2.8 0.0 0.3 7.3 0.1 1.0 0.0 0.0 0.3 0.2 0.2 0.8 0.3 2.4 0.0 5.8 0.3 0.4 0.1 0.9 0.0 0.2 1.4 0.3 2.9 0.1 1.4 1.9 0.1 0.5 0.6 0.6 0.5 0.7 1.8 0.0 0.9 0.0 0.3 6.3 0.8 0.2 0.1 4.1 0.0 0.0 1.4 2.0 0.0 12.3 0.0 9.9 14.5 0.3 0.1 5.7 4.0 0.5 1.0 0.0 0.2 0.4 0.0 0.4 1.7 2.2 0.4 1.9 0.2 1.4 0.8 1.0 0.1 1.2 1.0 0.9 1.5 2.0 1.4 0.0 1.4 2.1 0.9 2.3 0.3 3.2 0.1 3.7 0.7 1.4 3.0 1.5 2.6 2.3 2.1 2.6 2.1 2.8 1.0 1.7 2.8 0.3 0.0 0.0 2.0 0.9 0.0 0.0 0.0 0.0 14.4 0.1 0.5 0.8 4.3 0.0 5.5 22.9 0.1 0.3 0.0 0.0 0.6 0.0 0.4 0.4 0.2 4.9 0.0 13.1 0.0 0.0 0.2 0.5 0.5 0.0 0.0 1.4 0.8 0.4 0.0 13.9 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 3.7 0.2 2.2 3.1 11.1 9.3 0.1 0.6 0.4 0.3 0.1 0.3 2.8 0.1 11.6 0.0 3.6 0.4 0.0 0.7 0.0 0.0 0.0 0.8 0.1 0.2 0.1 TMEM170A "FLJ37611, TMEM170" ENSG00000166822 "Transmembrane protein 170A" Q8WVE7 16 75443054-75465497 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.49e-1)" "unprognostic (1.18e-1)" "unprognostic (2.95e-2)" "unprognostic (1.52e-3)" "unprognostic (1.08e-1)" "unprognostic (3.33e-2)" "unprognostic (1.02e-2)" "unprognostic (8.62e-2)" "unprognostic (7.97e-2)" "unprognostic (3.19e-2)" "unprognostic (1.53e-1)" "unprognostic (7.15e-2)" "prognostic favorable (2.36e-9)" "unprognostic (4.37e-2)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (1.53e-3)" 8.2 9.8 7.7 10.6 10.6 36.6 6.0 9.2 9.0 7.7 7.9 12.1 14.5 8.0 6.0 8.4 7.6 7.8 7.2 7.4 9.3 9.2 12.7 8.0 11.9 11.3 10.2 10.2 10.2 3.9 8.7 10.2 9.9 7.6 10.1 14.9 6.5 3.2 3.7 7.8 13.7 6.3 9.3 9.2 7.3 17.4 8.5 6.8 9.7 4.9 9.7 8.1 7.8 16.9 14.2 17.1 21.8 22.3 9.5 7.7 38.9 9.2 5.2 7.4 11.3 35.3 30.7 19.6 17.0 4.4 16.4 25.9 18.3 8.9 13.0 12.0 11.4 10.6 16.4 22.4 6.3 25.3 27.3 6.7 6.8 12.5 9.4 8.7 6.5 22.7 21.8 15.2 3.9 28.8 22.3 16.8 26.1 17.2 9.2 43.5 8.5 15.7 5.1 18.3 12.8 14.9 22.4 7.0 12.6 25.6 9.4 11.6 9.6 12.6 21.4 10.1 10.2 13.7 17.3 60.3 9.8 14.7 14.4 14.5 26.6 38.2 27.9 29.1 36.6 28.9 29.1 31.8 24.0 28.8 30.9 27.3 33.3 25.4 26.9 26.8 23.1 21.6 7.7 10.6 9.2 9.0 7.4 9.3 11.3 10.2 9.9 9.3 8.5 16.9 39.7 19.2 15.0 20.5 49.0 19.9 45.7 37.8 26.7 25.6 37.7 27.1 9.3 40.0 25.3 20.2 37.5 73.0 65.0 86.2 25.4 26.8 40.5 62.5 23.6 37.2 34.1 17.1 17.6 19.3 51.5 24.3 16.8 67.7 28.6 57.3 35.3 24.2 37.2 37.0 15.9 37.6 22.4 31.8 29.7 8.7 24.2 38.3 21.4 11.2 41.2 43.7 42.2 24.1 29.8 23.3 67.6 21.4 29.2 57.5 53.5 30.2 32.4 38.3 32.9 19.9 20.1 88.5 61.8 19.7 20.0 53.4 49.0 36.7 56.0 67.8 TMEM174 "FLJ31268, MGC13034" ENSG00000164325 "Transmembrane protein 174" Q8WUU8 5 73173193-73175143 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 309 "kidney: 153.2" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 160.6" "Cancer enriched" "Detected in single" 126 "renal cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA037975 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA037975: AB_10672732" "unprognostic (8.11e-2)" "prognostic favorable (3.30e-6)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 153.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear membrane" "HPA057160: AB_2683356" "unprognostic (3.84e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-2)" "unprognostic (9.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (1.12e-2)" "unprognostic (3.25e-3)" "unprognostic (1.22e-2)" "unprognostic (1.50e-2)" "prognostic favorable (9.85e-5)" "unprognostic (4.71e-2)" "unprognostic (5.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (1.96e-1)" "unprognostic (7.51e-3)" 17.5 28.2 13.0 8.1 13.3 12.9 17.5 15.7 24.6 14.7 12.2 15.5 8.9 17.3 6.0 14.2 14.9 10.0 19.6 12.9 13.1 16.4 33.5 16.1 16.1 14.6 13.1 12.2 23.3 9.2 30.9 7.4 14.5 19.0 3.6 10.2 21.4 8.7 19.7 17.0 17.5 6.4 11.4 26.1 19.3 13.2 12.7 8.9 21.0 4.5 6.1 16.1 13.5 13.5 4.9 9.5 5.1 7.0 23.7 12.3 11.8 13.0 8.6 7.3 10.8 4.2 20.5 4.0 7.5 12.8 12.8 8.4 4.7 9.5 3.1 9.2 11.9 8.3 14.9 4.3 13.7 4.6 14.8 17.5 11.3 6.4 4.3 5.1 4.6 8.1 8.2 30.0 6.4 16.2 11.3 17.4 3.2 5.8 24.8 7.5 3.1 11.5 7.0 5.0 14.0 12.9 8.6 5.5 7.8 2.5 24.3 11.3 6.6 13.7 3.0 16.8 9.1 23.0 5.9 7.4 13.2 9.4 11.3 36.8 32.2 27.2 20.6 41.1 13.3 19.4 17.3 15.5 29.4 21.6 12.6 17.6 27.8 17.0 39.7 47.1 18.5 21.2 13.0 13.3 15.7 24.6 12.9 13.1 14.6 13.1 14.5 11.4 12.7 13.5 17.0 12.8 8.9 26.8 20.7 6.2 8.1 21.0 12.5 26.8 15.2 14.4 10.4 8.6 17.1 14.7 4.2 24.1 19.2 13.7 1.9 8.8 6.1 11.6 12.2 10.2 16.2 3.0 42.8 11.4 10.1 16.6 17.9 11.3 7.0 10.8 10.8 24.5 15.2 47.1 37.8 9.6 34.6 14.5 9.1 4.0 12.5 15.8 19.6 15.0 9.6 38.6 15.5 25.1 29.1 7.9 16.1 16.1 16.7 6.1 16.6 8.0 13.6 28.7 13.1 10.1 12.3 24.0 14.1 12.3 7.7 18.9 15.3 29.2 7.6 8.4 TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 66.5;Proximal tubular cells: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (1.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (9.81e-3)" "unprognostic (2.05e-3)" "unprognostic (3.17e-2)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (4.90e-1)" "unprognostic (6.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" 3.2 8.0 6.6 4.8 7.1 1.0 6.8 7.4 7.7 5.3 3.3 10.9 16.1 6.6 9.0 5.7 10.6 3.9 8.2 6.8 4.6 13.4 25.7 3.3 5.1 4.2 6.2 7.9 5.5 8.2 12.5 3.2 4.5 5.9 9.1 7.2 6.9 5.9 12.2 6.7 13.7 5.2 3.9 4.0 6.3 7.7 6.6 4.7 5.6 7.0 5.2 5.2 4.9 6.6 22.9 19.9 17.2 16.7 4.6 4.5 8.9 8.4 10.4 24.3 18.3 50.4 12.6 37.9 20.1 7.4 19.9 13.7 27.9 28.7 14.0 18.0 51.4 19.5 11.8 56.7 10.1 12.5 13.9 12.4 20.1 19.2 12.5 9.3 15.7 22.3 30.7 4.9 13.3 19.0 21.8 24.3 44.0 16.7 29.2 19.6 16.8 22.4 24.4 11.8 33.8 19.3 10.9 23.2 26.9 15.9 17.7 21.1 12.8 12.0 28.7 9.2 16.7 4.9 3.8 23.3 4.5 15.2 22.0 0.0 2.6 2.6 8.2 2.1 8.5 6.6 6.9 8.4 4.9 8.7 16.2 10.3 0.8 7.2 1.4 5.8 7.9 5.5 6.6 7.1 7.4 7.7 6.8 4.6 4.2 6.2 4.5 3.9 6.6 6.6 2.6 3.2 0.0 3.3 3.6 2.9 12.1 13.9 1.8 13.3 8.2 9.7 13.0 11.5 10.7 5.5 14.6 11.9 2.1 8.9 66.5 16.0 2.2 4.0 6.8 5.0 2.4 3.4 4.1 14.3 9.7 5.4 5.6 2.8 0.0 10.1 1.4 30.5 6.3 11.8 4.1 7.2 8.2 1.2 1.1 2.1 7.5 1.5 14.2 0.0 4.7 9.4 5.2 5.5 2.0 12.3 6.5 12.4 3.4 9.2 22.8 47.2 5.4 21.8 0.0 2.6 6.1 6.5 6.6 5.1 2.0 2.1 4.1 21.5 14.1 4.5 TMEM179 "C14orf90, FLJ42486, TMEM179A" ENSG00000258986 "Transmembrane protein 179" Q6ZVK1 14 104474678-104605647 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 31.5;pituitary gland: 88.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 58.1;Horizontal cells: 65.6" "Group enriched" "Detected in some" 4 "glioma: 2.7;pancreatic cancer: 3.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 8.8;SCLC-21H: 37.3;SH-SY5Y: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002942 Uncertain Mitochondria NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA002942: AB_1078113" "unprognostic (8.65e-2)" "unprognostic (8.24e-2)" "unprognostic (3.10e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.82e-3)" "unprognostic (1.09e-1)" "unprognostic (1.89e-4)" "unprognostic (8.68e-3)" "unprognostic (1.56e-1)" "unprognostic (9.71e-6)" "unprognostic (1.70e-2)" 0.2 11.4 18.9 0.3 19.3 0.0 0.1 12.0 29.7 0.1 4.6 3.8 0.2 0.1 0.4 0.1 0.3 0.1 1.0 17.8 24.6 0.5 0.5 0.1 0.0 25.9 24.9 0.1 4.0 0.1 88.1 0.8 31.5 0.8 0.2 6.2 0.1 0.1 0.1 0.0 1.4 0.3 12.5 0.0 1.3 5.2 18.8 0.0 0.1 0.0 0.0 0.1 0.7 20.5 0.0 0.5 0.3 0.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 37.3 11.6 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 19.3 12.0 29.7 17.8 24.6 25.9 24.9 31.5 12.5 18.8 20.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 1.2 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 65.6 12.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 1.5 0.0 7.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.7 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" 52.1 60.3 32.4 22.0 34.7 21.5 55.0 33.7 36.4 50.5 41.8 48.7 34.7 44.4 71.2 47.9 46.7 28.4 34.0 30.8 32.9 54.3 64.3 51.0 26.9 35.3 33.3 39.6 58.7 34.1 31.0 30.0 35.6 45.8 40.1 10.4 59.1 26.4 27.2 58.2 49.8 26.3 33.7 48.1 53.9 41.6 33.0 33.0 55.4 21.6 29.8 43.3 46.0 36.9 35.6 68.8 17.7 35.7 136.3 34.3 22.6 38.2 47.5 29.8 34.2 39.3 82.9 16.5 53.1 78.0 44.2 64.8 33.4 35.4 23.2 48.6 44.9 24.1 29.2 36.3 90.8 30.9 32.2 65.8 55.8 57.1 70.0 60.0 30.3 46.9 33.2 46.3 34.5 81.1 40.2 59.5 26.5 76.8 74.6 26.5 28.8 86.1 57.7 42.6 24.4 26.7 49.3 65.3 70.4 35.8 76.2 37.8 42.2 39.6 29.4 73.3 32.2 51.2 32.5 22.6 57.0 19.0 47.3 302.9 300.4 332.7 149.4 305.0 147.9 169.2 135.5 144.9 198.2 140.6 118.2 117.3 224.3 140.2 305.9 366.1 146.6 282.5 32.4 34.7 33.7 36.4 30.8 32.9 35.3 33.3 35.6 33.7 33.0 36.9 119.6 60.9 59.2 15.3 52.7 68.7 73.9 175.6 86.0 12.4 108.0 122.2 1.3 65.8 121.1 60.7 0.0 174.5 71.7 91.2 37.2 138.1 5.8 75.2 54.5 83.7 65.2 40.4 9.9 149.0 160.5 76.8 54.6 66.5 54.6 43.8 69.9 81.9 133.2 8.4 9.0 103.5 128.1 63.7 83.0 11.0 75.8 76.5 106.7 12.2 98.3 74.4 91.6 16.1 28.1 124.0 137.1 45.9 93.9 97.1 179.4 87.5 122.9 14.7 65.7 50.5 57.8 120.8 100.5 93.2 76.0 185.1 60.0 90.4 94.8 97.5 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 94.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 65.9;Intestinal goblet cells: 40.4;Paneth cells: 41.7;Proximal enterocytes: 60.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 34.2;RT4: 37.9;SCLC-21H: 40.8;SK-BR-3: 58.4;T-47d: 53.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" 0.4 0.3 0.1 1.4 0.1 0.7 3.0 0.1 1.0 20.6 0.2 12.1 24.4 1.1 0.3 94.6 7.0 3.6 0.4 0.0 0.2 6.2 24.4 2.2 0.2 0.2 0.0 0.2 22.9 5.2 11.4 1.7 0.1 11.3 6.6 0.1 22.5 4.5 4.9 37.0 23.6 0.3 0.0 0.1 12.6 3.7 0.2 0.6 0.6 0.6 4.3 12.8 41.0 0.1 23.7 15.0 0.1 0.0 0.0 0.1 5.0 0.8 0.3 0.9 0.1 20.9 25.4 0.5 7.6 0.3 7.5 17.0 0.0 9.7 0.3 0.2 0.9 0.1 15.3 9.7 0.2 0.0 0.0 0.0 8.9 0.3 8.0 0.4 0.1 6.3 0.2 0.1 0.0 34.2 0.2 0.1 0.7 13.5 19.3 0.5 0.0 10.9 7.3 37.9 40.8 0.1 6.4 58.4 0.1 0.5 53.7 0.1 0.0 0.0 8.2 9.7 1.1 0.1 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.1 2.9 3.2 4.4 0.0 1.6 4.0 5.8 7.2 2.2 1.1 12.1 5.5 7.5 11.5 18.2 9.2 0.0 7.1 1.4 65.9 1.9 13.2 0.0 19.3 3.4 1.4 7.2 0.0 0.3 11.0 8.7 1.7 23.4 31.7 1.3 0.5 0.0 14.2 0.8 0.0 0.1 40.4 14.2 0.6 2.6 0.0 0.0 1.4 0.0 0.0 0.6 0.5 0.0 0.0 0.0 13.1 41.7 0.0 4.6 10.4 60.5 5.1 28.0 0.6 0.0 1.8 3.0 0.0 0.1 15.4 9.2 16.8 1.2 0.1 19.4 16.0 TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.8;Late spermatids: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Cell Junctions" "HPA018226: AB_1845579, HPA063559: AB_2685041" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "unprognostic (2.98e-2)" "unprognostic (4.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.06e-2)" "unprognostic (9.35e-2)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.93e-8)" "unprognostic (1.06e-1)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" 7.0 11.2 8.6 6.2 9.0 2.2 10.0 8.8 10.5 6.5 9.2 10.8 9.6 7.5 12.5 9.6 9.3 4.6 13.2 8.5 8.9 12.3 16.3 5.8 8.6 8.6 8.7 8.5 8.9 12.4 9.5 7.2 8.8 7.5 11.2 5.0 8.3 7.2 18.5 8.3 9.7 7.5 8.6 9.9 9.5 7.8 8.9 7.9 7.6 21.3 10.7 7.5 6.5 9.2 10.4 16.1 11.8 15.1 19.8 10.5 11.2 11.8 12.1 15.2 12.5 15.9 17.1 31.9 9.8 8.7 10.4 19.8 21.2 16.8 17.3 18.7 20.4 13.4 22.3 34.1 22.0 15.1 10.3 12.7 27.8 16.7 24.4 12.5 14.0 25.9 23.3 17.1 9.0 28.3 11.7 14.7 15.0 22.0 13.9 24.4 15.5 35.3 16.3 8.8 18.1 17.3 16.2 22.7 14.3 12.0 27.1 12.0 8.9 10.8 15.1 27.0 9.9 15.6 17.6 15.5 16.8 27.1 8.8 9.9 8.7 6.8 7.5 8.6 10.0 13.1 8.1 8.8 9.1 11.5 13.7 10.9 4.1 9.1 13.3 7.0 11.7 7.4 8.6 9.0 8.8 10.5 8.5 8.9 8.6 8.7 8.8 8.6 8.9 9.2 3.4 6.4 6.7 2.6 6.7 8.2 7.1 16.1 5.7 6.9 7.3 6.6 2.7 10.0 13.1 11.0 0.0 23.4 4.4 7.8 21.5 15.1 44.8 4.8 6.0 5.6 13.8 8.2 1.9 11.2 13.3 5.7 6.1 5.0 7.0 9.6 6.1 12.8 13.2 13.5 1.5 9.4 12.2 4.9 4.7 106.9 9.3 2.5 7.2 1.0 9.9 10.8 11.3 1.5 1.9 9.9 6.7 6.4 5.1 9.8 14.8 21.9 9.3 5.6 13.1 6.6 5.3 21.3 11.9 9.5 9.5 15.1 5.0 11.0 16.0 5.8 TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "HPA016830: AB_1858107" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (6.76e-2)" "unprognostic (1.44e-1)" "unprognostic (4.45e-1)" "unprognostic (3.43e-2)" "unprognostic (7.60e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-2)" "unprognostic (4.42e-1)" "unprognostic (5.32e-3)" "unprognostic (1.00e-1)" 11.4 10.9 8.0 16.9 9.5 8.1 20.6 9.9 8.8 13.3 12.4 27.2 34.4 8.1 9.8 31.1 12.2 11.0 15.7 8.3 10.5 38.3 24.7 16.2 18.7 10.5 9.8 4.2 16.2 15.2 6.9 9.4 10.4 7.5 20.3 13.8 12.5 13.0 25.2 21.7 30.1 14.8 10.8 18.2 14.7 7.1 9.1 20.1 13.6 21.9 30.9 19.4 16.6 12.3 35.9 45.5 30.8 18.2 47.7 22.0 18.6 28.4 33.8 32.7 28.5 22.2 32.3 66.2 38.0 54.4 27.2 45.9 27.1 30.6 43.8 48.5 32.4 38.4 29.4 25.1 13.1 40.9 37.1 20.0 33.7 41.8 13.6 26.1 35.6 58.4 23.0 37.9 49.9 17.4 39.7 11.9 17.3 22.3 30.1 29.8 45.4 37.8 30.0 82.1 33.7 26.8 49.6 25.5 12.9 23.5 38.2 12.1 35.1 45.8 22.2 20.1 25.9 73.9 101.4 47.7 19.4 11.7 50.0 26.0 27.1 10.4 33.2 34.3 25.7 102.3 26.1 28.2 47.6 118.6 25.2 30.3 2.3 28.8 31.3 134.5 29.8 33.7 8.0 9.5 9.9 8.8 8.3 10.5 10.5 9.8 10.4 10.8 9.1 12.3 12.8 22.4 16.3 9.8 44.7 19.1 18.8 32.7 14.8 12.9 11.7 5.8 22.4 12.8 20.1 25.8 12.5 13.6 37.9 21.9 11.7 15.8 16.4 7.4 6.0 14.9 19.9 9.9 7.2 21.6 25.1 11.8 6.6 7.5 15.8 7.4 16.4 31.1 25.9 15.2 9.2 14.5 34.6 32.1 33.7 75.3 7.5 24.2 23.2 5.6 21.4 11.0 22.6 9.5 12.2 22.1 20.2 13.5 54.8 6.9 51.2 46.1 30.6 8.8 6.6 7.5 9.0 4.4 8.4 43.8 46.5 4.8 12.4 7.7 27.4 16.6 TMEM199 "C17orf32, MGC45714, VMA12, VPH2" ENSG00000244045 "Transmembrane protein 199" Q8N511 17 28357642-28363683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027051 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA027051: AB_10600915" "unprognostic (3.01e-1)" "unprognostic (3.45e-2)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.55e-4)" "unprognostic (9.98e-2)" "unprognostic (4.60e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.67e-2)" "unprognostic (5.26e-2)" "unprognostic (1.78e-1)" "unprognostic (6.38e-3)" "unprognostic (1.09e-1)" "unprognostic (9.25e-2)" "unprognostic (2.75e-1)" "unprognostic (1.99e-1)" "unprognostic (3.51e-3)" "unprognostic (5.95e-2)" 8.3 11.9 9.2 10.3 10.4 13.3 8.6 10.1 13.0 9.1 9.6 9.0 7.4 9.5 9.6 10.6 8.0 6.2 9.3 9.5 10.5 12.9 14.4 8.5 12.7 10.2 10.1 8.0 8.9 15.5 11.7 9.5 10.1 9.8 7.9 13.9 9.5 6.8 7.2 11.6 9.0 6.2 9.5 13.2 8.9 7.8 10.4 12.8 10.8 7.5 11.2 8.8 8.8 12.0 12.2 20.4 19.6 16.7 7.9 6.8 16.5 14.8 9.5 20.6 18.5 48.9 9.6 17.6 14.8 11.0 26.4 20.6 21.8 13.9 18.0 32.8 19.6 13.0 17.7 23.6 15.9 18.7 22.0 9.7 12.6 19.6 13.0 12.2 10.2 16.1 21.6 21.8 15.4 24.1 21.3 25.6 16.2 21.0 13.9 17.2 24.4 16.3 15.5 20.2 24.8 26.0 17.8 45.6 27.1 20.1 28.7 16.9 14.0 17.4 13.5 15.0 25.3 29.3 38.9 16.2 21.6 11.4 22.2 28.5 24.2 20.0 15.1 25.2 16.6 17.1 13.1 13.4 20.0 16.0 16.4 14.5 18.9 15.6 23.0 14.0 14.9 19.1 9.2 10.4 10.1 13.0 9.5 10.5 10.2 10.1 10.1 9.5 10.4 12.0 12.4 32.1 8.6 8.8 21.0 5.7 10.5 34.3 15.4 13.8 14.3 14.4 5.6 12.8 23.5 9.2 8.4 40.2 15.5 21.1 43.0 40.2 3.7 12.0 11.4 14.6 15.6 12.2 11.0 31.4 38.1 10.6 7.7 10.9 7.6 11.9 17.5 26.8 51.3 11.8 10.5 15.7 32.6 22.9 9.5 4.5 11.5 22.4 21.4 6.5 45.0 19.1 25.7 7.5 13.7 35.4 19.4 6.4 15.1 13.1 20.3 54.0 15.1 14.0 13.1 8.6 14.2 26.5 35.4 14.0 8.8 48.4 15.2 14.7 13.0 11.4 TMEM200A "KIAA1913, TTMC" ENSG00000164484 "Transmembrane protein 200A" Q86VY9 6 130366017-130443067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.5;Distal enterocytes: 23.3;Endometrial stromal cells: 18.6;Enteroendocrine cells: 24.6;Granulosa cells: 49.9" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "HBF TERT88: 40.8;hTEC/SVTERT24-B: 67.1;hTERT-RPE1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014396 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA014396: AB_2204904" "unprognostic (1.07e-1)" "unprognostic (4.89e-2)" "unprognostic (2.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.62e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (2.91e-1)" "unprognostic (7.25e-2)" "unprognostic (9.29e-2)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.27e-3)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (1.91e-3)" 5.7 17.1 1.7 3.9 2.5 0.1 5.9 0.1 2.2 11.1 0.0 11.1 7.3 39.3 5.3 1.2 12.9 6.4 0.6 4.5 2.7 13.6 0.4 6.8 3.8 0.9 4.6 15.6 1.5 0.8 5.3 3.3 1.5 2.7 22.3 11.2 1.6 1.4 0.6 2.0 8.3 18.7 0.8 1.0 6.3 2.7 3.8 4.7 5.6 0.4 3.4 5.6 3.5 0.8 0.1 0.1 0.2 0.0 11.7 14.6 0.1 10.6 13.0 11.1 19.6 16.6 0.0 0.0 0.0 22.3 2.5 2.5 1.0 0.0 40.8 15.5 0.0 0.0 0.0 0.8 5.3 0.3 0.0 16.7 0.0 67.1 13.3 33.5 0.4 0.3 0.0 1.5 5.2 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 13.4 12.5 4.0 1.1 1.9 8.2 0.0 0.0 7.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.8 0.4 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 1.7 2.5 0.1 2.2 4.5 2.7 0.9 4.6 1.5 0.8 3.8 0.8 0.5 0.0 0.5 1.3 0.2 2.0 0.1 0.1 1.2 26.5 0.5 0.4 0.6 0.0 0.0 0.0 0.0 0.5 0.4 23.3 0.0 0.0 2.0 5.2 18.6 0.8 24.6 2.7 7.1 0.0 1.7 3.6 2.0 0.7 0.0 49.9 0.0 0.0 0.2 13.5 4.3 1.6 0.0 0.0 0.9 1.8 5.9 0.3 1.8 1.9 0.0 0.5 0.0 1.0 0.3 0.1 6.0 10.5 3.3 0.0 4.6 9.9 0.0 2.1 0.0 0.8 8.4 3.3 2.6 0.1 1.4 0.5 5.8 11.3 4.0 0.1 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM200C TTMA ENSG00000206432 "Transmembrane protein 200C" A6NKL6 18 5882072-5895955 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7;salivary gland: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.3;Cone photoreceptor cells: 6.2;Inhibitory neurons: 8.0;Oligodendrocyte precursor cells: 17.6" "Cancer enhanced" "Detected in single" "glioma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;NTERA-2: 4.7;PC-3: 22.0;U-2 OS: 10.9;U-251 MG: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047253, HPA050490" Uncertain Approved Microtubules NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules "HPA047253: AB_2680001, HPA050490: AB_2681144" "unprognostic (6.57e-4)" "unprognostic (3.09e-1)" "unprognostic (1.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.29e-2)" "unprognostic (6.31e-2)" "unprognostic (3.82e-4)" "unprognostic (2.48e-10)" "unprognostic (2.94e-2)" "unprognostic (6.38e-2)" "unprognostic (7.22e-2)" "unprognostic (2.38e-2)" 0.2 3.9 2.2 0.3 2.2 0.0 0.6 0.3 2.2 0.7 0.0 0.5 0.1 0.5 1.1 0.2 0.5 0.4 2.1 1.0 2.5 1.6 1.0 0.1 0.4 2.2 7.7 0.7 0.0 0.1 2.3 0.0 2.6 0.7 0.0 0.8 5.5 0.2 0.0 0.2 0.6 0.1 2.5 0.6 0.4 0.9 2.6 0.1 0.1 0.0 0.3 0.4 0.1 0.9 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 22.0 1.3 0.0 0.0 0.0 0.0 1.1 3.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 10.9 0.0 3.9 0.0 0.0 0.0 1.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.2 0.3 2.2 1.0 2.5 2.2 7.7 2.6 2.5 2.6 0.9 0.1 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.0 9.3 0.5 2.0 2.4 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 2.0 3.4 0.1 0.7 0.0 0.0 1.6 0.0 0.1 2.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.4 1.1 1.2 0.2 0.0 1.0 0.0 0.8 0.0 17.6 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.0 1.4 0.3 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.1 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: AB_10603135" "unprognostic (3.03e-1)" "unprognostic (5.06e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (5.98e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (3.19e-1)" "unprognostic (6.00e-2)" "unprognostic (2.34e-3)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.68e-2)" "unprognostic (3.24e-1)" 8.9 15.3 4.1 8.4 6.2 9.6 10.6 7.2 6.5 7.4 13.0 11.0 8.8 10.8 9.5 5.5 9.6 6.4 6.2 4.0 5.2 8.6 10.4 9.2 11.9 6.1 6.1 10.2 8.5 15.1 4.4 9.5 6.4 8.3 11.2 13.3 7.9 8.4 5.2 7.2 10.7 9.0 5.9 10.5 7.6 15.0 5.4 14.2 16.2 7.7 12.1 7.6 4.3 9.6 23.4 21.8 29.3 36.7 16.8 17.2 21.4 20.8 20.9 18.3 24.7 23.0 39.2 34.6 15.1 13.3 34.5 34.2 34.7 24.2 33.0 42.7 20.0 17.9 34.0 16.5 29.6 38.2 17.2 18.9 24.6 37.0 36.8 11.4 14.5 35.1 58.9 38.2 23.2 30.2 73.2 23.6 44.1 20.9 19.4 38.9 33.1 57.4 19.1 29.3 26.2 40.0 47.5 75.8 31.3 22.7 23.7 25.6 11.4 33.0 13.1 35.4 50.6 51.7 81.6 70.4 54.7 43.4 53.0 16.1 12.2 13.8 22.0 18.3 23.0 18.3 22.3 20.2 12.0 17.3 25.6 22.3 1.8 19.5 16.8 14.9 24.6 15.1 4.1 6.2 7.2 6.5 4.0 5.2 6.1 6.1 6.4 5.9 5.4 9.6 12.3 3.2 12.3 11.4 15.3 4.7 4.0 8.2 6.8 13.6 8.8 5.2 8.6 10.0 9.8 9.2 4.2 8.9 15.2 7.2 1.9 6.4 33.5 9.6 8.0 9.5 13.8 25.9 10.4 9.1 9.3 7.5 7.7 10.4 10.1 10.0 9.7 9.4 7.9 5.0 13.0 11.9 8.2 13.1 4.4 8.5 6.5 7.8 7.2 15.0 7.7 18.1 8.2 10.6 20.9 7.6 11.6 5.3 11.0 5.3 13.4 4.9 9.8 14.6 0.0 9.0 5.9 16.6 16.0 6.4 5.4 6.6 13.1 12.1 9.5 3.7 TMEM211 bA9F11.1 ENSG00000206069 "Transmembrane protein 211" Q6ICI0 22 24934954-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.6;salivary gland: 5.8;stomach 1: 3.2" "Cell type enriched" "Detected in some" 19 "Ionocytes: 36.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 4.8;endometrial cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA066784: AB_2685722" "unprognostic (7.89e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-2)" "unprognostic (5.97e-3)" "unprognostic (5.88e-2)" "unprognostic (1.31e-3)" "unprognostic (3.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-2)" "unprognostic (8.61e-3)" "unprognostic (3.59e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.3 0.2 2.6 0.0 0.3 0.0 0.6 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 5.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.3 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" 45.8 39.0 14.7 30.8 15.8 23.1 43.2 15.3 17.3 45.0 28.7 38.3 30.5 43.7 66.2 31.5 37.5 30.7 36.7 14.8 17.0 30.0 46.5 37.7 25.1 19.1 18.7 41.4 79.9 56.0 60.4 45.8 18.3 37.9 41.7 8.8 83.6 44.4 35.7 37.8 33.6 45.1 15.6 37.4 40.8 19.5 17.8 21.7 42.3 21.3 34.4 36.7 33.9 14.9 82.4 53.5 32.2 68.2 102.8 103.7 69.4 105.9 142.4 76.0 85.2 53.0 67.3 37.6 52.4 156.6 59.7 57.6 39.3 74.9 61.0 36.3 44.1 49.9 41.4 109.8 128.1 45.7 82.5 90.4 52.7 66.8 112.0 58.6 83.5 24.3 46.0 75.3 85.9 59.6 23.3 34.1 23.1 110.0 42.8 31.3 58.5 91.0 57.1 57.0 27.8 32.3 49.4 83.3 38.2 31.0 45.9 27.0 72.4 55.2 52.8 57.0 60.4 100.9 73.3 59.2 71.1 56.8 77.9 5.7 3.5 2.8 3.9 3.8 5.0 2.5 3.0 2.8 2.8 2.8 1.5 2.1 0.6 5.6 2.2 5.0 2.6 2.5 14.7 15.8 15.3 17.3 14.8 17.0 19.1 18.7 18.3 15.6 17.8 14.9 15.8 3.2 20.1 3.9 18.5 7.6 9.6 10.4 3.4 9.3 19.8 11.0 8.2 21.5 15.0 14.7 10.4 43.6 15.0 37.5 1.9 24.7 6.4 11.3 25.4 17.5 17.9 18.5 4.8 34.6 62.9 26.9 33.1 23.8 14.5 17.0 32.5 28.9 27.3 6.7 4.4 37.6 10.2 18.9 12.8 7.8 32.6 11.7 5.4 6.5 14.6 6.9 14.4 4.0 3.8 21.7 22.3 20.3 63.0 20.8 25.4 10.4 11.0 8.4 26.3 11.6 19.6 24.4 12.7 8.4 9.2 71.7 12.0 17.6 27.6 15.8 TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.9;retina: 18.3;testis: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 572.0;Early spermatids: 129.9;Late spermatids: 302.1" "Cancer enriched" "Detected in single" 14 "thyroid cancer: 4.9" "Region enriched" "Detected in many" 4 "thalamus: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA052804, HPA063207" Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA052804: AB_2681957, HPA063207: AB_2732697" "unprognostic (1.31e-2)" "unprognostic (4.57e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (5.85e-2)" "unprognostic (4.38e-3)" "unprognostic (2.17e-3)" "unprognostic (2.82e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.32e-2)" 0.0 0.0 1.2 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.2 1.6 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.9 6.9 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.5 0.7 1.5 0.2 1.6 0.3 0.3 6.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 572.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.9 0.0 1.2 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 302.1 2.8 0.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.1 3.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM216 "CORS2, HSPC244, JBTS2, MGC13379, MKS2" ENSG00000187049 "Transmembrane protein 216" Q9P0N5 11 61392360-61398863 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 192.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (7.75e-2)" "unprognostic (1.54e-1)" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (9.02e-3)" "unprognostic (4.44e-2)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-2)" "unprognostic (9.66e-2)" "unprognostic (2.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (8.03e-3)" 12.5 12.5 22.2 8.0 22.0 16.5 18.8 22.0 23.8 16.4 22.2 10.4 8.5 11.6 18.0 10.7 20.4 10.0 8.4 21.6 22.4 15.1 6.4 8.3 13.7 22.2 22.7 28.3 15.6 11.4 20.8 13.3 21.7 13.2 11.7 11.8 15.9 12.9 4.3 9.6 11.3 10.7 22.1 14.7 11.3 14.8 22.9 12.7 12.7 6.9 16.5 13.9 12.2 21.5 13.9 15.1 23.2 18.6 37.6 18.2 5.6 7.8 11.9 16.9 12.1 24.3 24.4 5.1 25.6 13.0 0.1 18.1 26.1 14.7 19.6 41.2 16.8 9.7 9.3 32.2 21.7 51.8 14.6 16.0 22.7 10.2 20.2 6.1 16.4 1.7 21.7 11.1 10.9 57.9 3.7 84.1 24.8 44.9 34.2 0.6 18.8 16.2 14.5 32.8 10.6 16.9 19.6 11.3 14.4 17.3 12.8 26.4 7.5 0.1 0.6 8.5 0.1 9.1 6.9 7.9 0.2 20.6 8.0 87.2 28.1 192.7 32.5 31.0 30.7 50.5 34.1 32.3 33.9 49.9 36.0 30.5 44.3 68.6 26.1 12.3 42.0 23.6 22.2 22.0 22.0 23.8 21.6 22.4 22.2 22.7 21.7 22.1 22.9 21.5 11.7 6.4 9.7 11.1 17.8 4.7 17.5 30.8 23.3 4.2 18.8 29.8 2.9 11.5 14.5 1.8 2.1 19.6 11.9 5.1 19.6 14.0 5.7 8.5 15.7 11.3 9.6 12.6 4.0 16.9 20.6 18.5 5.1 5.6 8.8 14.1 12.5 2.0 14.1 5.0 4.1 11.6 14.2 6.2 5.2 2.4 21.1 8.6 7.2 4.7 7.9 25.4 24.7 4.5 2.2 12.5 8.6 13.5 13.9 23.6 8.1 9.2 19.1 5.4 13.1 11.7 9.3 36.5 20.8 19.3 3.4 8.6 16.7 14.5 11.5 14.1 TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" 17.7 18.1 4.8 9.5 5.5 5.3 14.0 5.3 6.5 15.5 5.3 13.5 8.4 16.6 6.9 11.6 14.8 7.4 10.2 4.6 5.4 12.7 12.9 12.0 10.5 6.0 5.5 15.0 14.5 10.3 15.2 5.9 5.8 13.0 6.0 6.5 10.9 6.8 9.2 8.9 11.8 8.3 5.7 16.6 13.2 5.6 5.1 8.4 10.9 5.7 7.0 13.8 13.2 6.3 12.5 24.0 14.9 18.2 13.5 18.6 9.0 12.2 9.2 9.3 12.0 2.5 35.9 15.6 29.9 7.5 14.2 14.2 9.4 11.6 12.2 22.0 13.5 35.1 6.1 10.0 13.3 11.1 12.6 14.7 15.2 16.5 19.6 14.9 13.7 19.1 14.4 19.4 16.2 6.4 2.9 23.3 12.2 34.0 22.6 16.3 18.0 12.0 8.3 12.3 12.9 19.4 16.6 6.6 9.1 8.7 31.3 15.7 17.6 11.4 10.3 13.4 13.5 11.1 10.1 12.9 9.1 22.9 20.3 43.7 40.1 17.4 21.6 31.6 18.7 29.6 20.5 20.5 47.4 23.9 17.2 20.4 15.7 32.5 30.9 41.1 20.5 27.0 4.8 5.5 5.3 6.5 4.6 5.4 6.0 5.5 5.8 5.7 5.1 6.3 21.0 19.2 13.4 7.8 17.8 12.1 19.6 34.6 19.4 7.0 22.1 24.6 8.1 15.7 16.6 14.7 0.0 28.0 18.1 5.7 27.4 20.5 3.4 23.1 22.4 15.8 10.8 14.5 4.4 16.2 18.4 21.1 8.6 10.6 3.8 22.2 18.5 15.1 42.2 23.5 7.4 11.7 20.3 21.0 17.5 1.9 10.2 21.9 17.8 14.0 26.0 26.0 18.6 9.5 11.2 13.1 3.9 16.6 15.8 9.4 8.5 19.7 29.4 12.4 26.3 16.7 18.3 16.6 13.8 18.0 14.2 9.7 14.5 27.0 13.7 16.6 TMEM219 IGFBP-3R ENSG00000149932 "Transmembrane protein 219" Q86XT9 16 29940885-29973050 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 637.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059185 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "HPA059185: AB_2683941" "unprognostic (4.13e-2)" "unprognostic (1.94e-3)" "unprognostic (1.51e-1)" "prognostic favorable (5.79e-4)" "unprognostic (2.62e-1)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (9.83e-2)" "unprognostic (8.53e-2)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-3)" 119.7 181.1 246.7 50.2 256.4 79.4 117.6 241.4 280.2 103.6 249.0 130.4 121.9 85.0 164.7 119.1 130.0 89.8 130.4 234.5 239.8 173.7 194.7 125.0 75.3 252.4 244.6 107.9 161.6 109.3 105.2 55.9 243.8 139.5 88.2 39.7 175.9 97.7 101.4 121.4 127.7 65.6 252.5 138.3 170.6 140.6 251.1 62.5 114.0 89.3 73.4 110.7 100.6 247.5 58.8 70.2 60.1 77.8 157.0 161.8 68.5 59.7 123.2 87.7 113.3 34.4 168.4 46.3 111.2 151.1 63.9 34.0 35.5 82.0 43.3 81.6 68.0 44.3 53.3 114.2 181.1 29.8 108.5 146.5 124.0 63.0 55.2 166.7 142.6 126.2 30.9 95.4 115.5 63.8 41.1 98.2 34.8 119.3 45.4 81.8 37.6 107.5 158.8 38.4 33.8 67.1 20.5 40.7 110.7 81.0 66.6 109.7 79.5 69.9 41.7 36.0 28.3 74.0 24.2 39.5 93.9 99.0 59.2 471.8 333.2 450.9 146.6 253.1 151.0 213.7 205.9 154.2 274.5 206.2 191.3 149.2 154.9 132.7 187.3 298.5 246.2 328.3 246.7 256.4 241.4 280.2 234.5 239.8 252.4 244.6 243.8 252.5 251.1 247.5 174.0 70.5 122.2 16.0 82.3 67.0 134.0 207.4 84.8 23.7 239.3 258.4 73.2 167.3 158.1 176.6 10.4 80.4 85.6 309.2 252.4 183.3 181.0 107.8 67.0 143.2 180.4 39.3 10.8 238.7 225.3 97.1 87.7 97.1 142.5 84.1 213.5 165.7 269.2 16.8 13.4 273.1 154.6 260.8 149.8 524.8 86.6 189.8 167.2 6.5 192.0 119.6 114.4 12.5 23.8 213.7 333.7 100.4 95.8 136.2 637.1 371.1 183.7 30.7 52.6 54.8 92.5 101.1 117.5 119.1 78.6 71.1 89.4 118.7 227.9 215.0 TMEM220 ENSG00000187824 "Transmembrane protein 220" Q6QAJ8 17 10699015-10730023 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 103.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 173.3;Proximal enterocytes: 576.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 9.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.71e-2)" "unprognostic (4.60e-2)" "unprognostic (6.31e-3)" "unprognostic (4.04e-3)" "unprognostic (1.05e-3)" "unprognostic (1.84e-4)" "prognostic favorable (2.23e-5)" "unprognostic (4.58e-2)" "unprognostic (4.96e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.97e-1)" "unprognostic (4.34e-3)" "unprognostic (2.25e-1)" "unprognostic (2.63e-2)" "unprognostic (7.80e-3)" "unprognostic (5.97e-2)" 8.6 10.9 3.3 4.9 3.8 5.8 7.2 3.3 3.3 6.4 5.5 8.2 15.7 6.9 4.5 4.3 6.1 5.1 5.1 3.3 3.7 10.3 103.8 5.5 6.2 4.2 3.8 6.9 9.5 3.6 3.2 3.2 4.7 21.7 4.9 19.0 5.5 7.8 8.1 6.6 26.8 3.8 4.4 6.5 13.0 9.1 3.9 1.2 13.0 0.8 1.9 5.9 5.0 4.6 0.5 3.1 1.1 7.2 4.4 4.4 0.7 6.0 6.6 4.2 5.7 0.0 0.3 0.7 0.4 4.0 0.2 0.4 2.8 0.2 3.0 0.3 1.2 0.4 0.1 2.7 6.7 0.8 0.7 3.0 0.3 1.3 0.3 0.8 1.9 2.7 0.3 0.2 2.6 0.4 1.1 1.3 4.4 0.4 0.0 4.4 0.2 0.5 9.8 0.2 0.4 5.5 0.3 0.1 0.7 1.5 0.3 1.6 4.4 0.2 0.9 2.2 0.4 0.7 0.3 0.2 4.3 1.1 0.4 1.6 2.1 2.1 0.7 1.6 0.9 4.0 1.8 1.1 2.6 9.0 7.4 5.2 1.6 4.2 0.7 1.9 0.4 1.7 3.3 3.8 3.3 3.3 3.3 3.7 4.2 3.8 4.7 4.4 3.9 4.6 10.1 3.2 11.0 18.3 7.5 9.6 17.7 9.2 23.3 2.5 20.9 26.4 11.6 57.2 9.9 18.4 8.4 12.0 3.1 41.3 21.5 18.0 99.0 6.1 16.3 8.1 3.0 21.7 1.4 23.6 20.6 16.3 33.6 7.6 40.0 13.4 16.1 173.3 24.0 0.0 2.8 32.6 4.1 13.5 6.4 22.2 18.0 13.1 24.9 12.2 4.6 55.0 5.2 17.6 1.6 12.6 32.5 9.8 6.6 36.5 576.7 31.7 6.9 23.6 19.7 17.2 12.7 90.6 8.7 20.7 8.0 4.5 3.0 30.0 21.1 22.3 TMEM222 "C1orf160, DKFZP564D0478" ENSG00000186501 "Transmembrane protein 222" Q9H0R3 1 27322145-27336400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016579, HPA059374" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Cell Junctions" "HPA016579: AB_2669392, HPA059374: AB_2683995" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-3)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (4.11e-2)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "unprognostic (1.96e-2)" "unprognostic (2.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-3)" "unprognostic (5.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.83e-2)" "unprognostic (7.80e-2)" 26.6 38.2 61.9 13.0 60.1 23.8 27.1 58.7 76.8 25.1 57.4 26.9 15.0 28.1 24.4 36.1 29.6 19.2 34.5 61.2 65.4 32.8 49.4 22.4 16.1 61.7 64.4 26.6 28.6 30.6 38.4 13.0 62.3 39.0 14.4 10.6 26.7 23.9 36.8 28.9 23.8 18.8 60.7 25.0 30.1 28.8 63.8 21.1 29.4 20.7 14.1 27.6 24.2 59.5 26.2 31.2 25.7 42.3 39.2 28.2 20.7 39.6 45.1 52.9 44.8 13.0 53.5 16.5 30.2 42.4 24.6 35.3 28.3 38.5 21.9 22.0 54.4 27.6 24.7 30.1 58.0 27.8 26.5 49.4 21.5 50.8 28.7 24.3 35.7 32.4 21.2 37.1 33.6 23.4 40.1 29.2 48.3 27.0 38.6 32.8 17.7 33.5 51.6 15.2 54.8 48.4 30.6 42.6 39.7 9.2 42.3 44.2 33.1 31.1 26.1 50.6 38.1 39.8 38.5 17.6 47.1 53.3 45.8 38.2 20.6 27.7 32.5 32.5 24.8 37.4 29.7 24.6 18.5 30.0 29.1 30.2 56.3 31.9 35.3 30.4 37.4 25.6 61.9 60.1 58.7 76.8 61.2 65.4 61.7 64.4 62.3 60.7 63.8 59.5 22.9 9.6 13.5 8.5 25.4 11.7 13.3 26.2 15.9 42.1 24.0 29.2 8.9 18.6 13.3 12.9 14.6 30.9 20.9 24.5 39.2 39.1 25.5 13.2 17.2 20.6 29.9 43.8 12.4 40.5 33.9 22.6 18.8 12.4 17.1 22.0 11.0 15.1 28.3 43.7 15.0 21.0 40.7 8.5 12.9 76.9 20.2 12.2 26.6 6.5 20.6 51.9 22.6 17.1 14.4 48.6 22.7 19.9 18.6 19.9 28.8 19.2 7.9 18.7 13.1 19.6 20.3 27.2 18.0 19.3 13.5 30.8 20.5 22.4 23.1 12.4 TMEM223 MGC3196 ENSG00000168569 "Transmembrane protein 223" A0PJW6 11 62771629-62792006 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014504 Approved Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA014504: AB_1853881" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (3.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-3)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (7.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.14e-3)" "unprognostic (9.75e-2)" 13.1 20.9 10.4 9.4 12.0 6.4 12.8 12.4 13.4 13.2 11.6 15.7 11.0 12.9 9.7 13.3 11.7 5.5 27.9 10.4 10.5 17.3 22.5 11.1 12.0 11.6 10.2 11.4 19.8 8.0 13.2 7.1 11.8 14.8 7.4 5.2 15.3 7.2 16.1 13.3 14.4 5.3 10.0 16.6 15.4 6.7 10.4 7.3 13.8 8.5 7.0 12.2 11.1 12.1 29.2 24.4 14.3 19.6 11.8 13.5 19.5 15.3 13.4 16.9 14.1 21.5 34.9 21.6 36.8 11.1 22.5 43.3 17.3 18.9 9.6 34.7 32.5 16.1 26.9 25.9 20.6 20.0 18.4 14.4 18.8 11.2 13.9 20.3 13.9 28.2 24.8 15.8 12.6 42.3 20.3 44.3 28.2 30.2 29.2 24.7 17.3 48.8 26.8 18.3 24.3 32.0 16.0 32.3 43.0 14.5 48.1 18.4 13.9 20.2 24.4 18.7 18.5 32.1 27.5 25.1 24.0 17.8 21.5 21.0 41.3 25.0 71.3 46.2 68.8 77.6 69.8 69.9 46.8 81.8 74.9 73.0 19.0 66.2 29.8 75.6 66.8 41.5 10.4 12.0 12.4 13.4 10.4 10.5 11.6 10.2 11.8 10.0 10.4 12.1 31.9 12.8 5.6 4.2 24.1 13.5 15.3 39.7 8.6 17.9 27.6 45.0 18.8 52.9 25.2 20.2 12.5 49.4 22.8 30.2 62.6 37.2 2.6 29.1 26.9 28.9 20.5 18.5 6.1 44.3 42.9 22.0 15.3 22.3 19.7 22.4 31.8 36.0 37.6 6.7 8.0 32.6 38.7 20.1 13.6 3.4 32.6 16.2 19.6 4.7 16.2 16.5 35.0 6.0 5.7 36.1 19.3 26.4 25.4 22.4 32.1 52.3 39.6 18.0 19.7 22.3 17.9 6.9 19.7 21.3 13.9 14.2 24.3 34.2 43.4 17.1 TMEM229B "C14orf83, FLJ33387" ENSG00000198133 "Transmembrane protein 229B" Q8NBD8 14 67447084-67533739 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Late spermatids: 25.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 19.1" "Cancer enhanced" "Detected in all" "melanoma: 12.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 12.9;MCF7: 13.6;SK-MEL-30: 11.6;U-937: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046562 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA046562: AB_10960265" "prognostic favorable (5.38e-4)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.21e-5)" "unprognostic (7.37e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (2.01e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (1.95e-2)" "unprognostic (5.18e-1)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.79e-5)" 1.5 15.3 10.1 5.6 8.7 1.8 3.7 21.2 15.8 10.8 0.0 4.3 15.7 1.4 10.9 1.3 2.0 4.1 1.3 10.9 10.7 2.0 1.1 3.5 9.1 25.8 10.9 1.1 5.0 12.5 6.9 0.8 27.6 2.7 3.3 5.4 4.0 10.4 0.5 1.4 14.2 3.2 10.4 9.8 4.2 6.1 15.4 11.8 8.3 0.9 6.1 5.0 1.5 11.5 3.2 0.4 0.0 0.8 0.3 0.0 1.2 0.5 0.7 0.8 3.3 0.0 10.1 12.9 0.1 0.3 2.8 0.0 0.2 0.7 0.1 4.2 1.0 7.8 0.0 0.0 1.0 8.5 1.5 0.2 0.4 0.1 0.0 0.2 0.0 0.8 0.1 0.5 0.0 13.6 5.2 3.2 0.1 6.7 0.6 4.7 0.1 1.9 0.1 6.7 1.9 0.4 0.0 4.9 11.6 0.5 10.3 8.1 0.0 0.1 0.5 0.1 0.2 0.0 0.0 0.0 0.6 34.5 7.0 5.8 5.7 9.1 9.9 6.5 9.5 1.3 5.9 8.0 2.7 0.9 5.0 6.5 0.1 5.5 6.9 1.5 2.5 5.8 10.1 8.7 21.2 15.8 10.9 10.7 25.8 10.9 27.6 10.4 15.4 11.5 1.2 0.0 0.5 1.3 2.6 0.3 0.3 3.6 0.0 4.8 3.5 2.5 1.8 2.8 2.5 0.0 14.6 0.1 8.3 3.6 0.0 2.0 12.6 2.3 0.3 1.4 2.4 0.4 7.1 3.6 0.0 0.6 1.1 0.3 0.0 11.0 2.9 0.2 1.8 0.0 10.6 5.3 0.0 6.2 1.0 25.7 0.0 2.6 7.2 3.7 5.5 0.3 15.5 19.1 6.1 0.5 5.7 0.7 0.4 0.4 11.3 2.2 2.4 4.1 0.0 0.2 0.7 0.7 0.3 0.1 0.1 0.1 4.1 4.9 3.9 1.1 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM232 FLJ43080 ENSG00000186952 "Transmembrane protein 232" C9JQI7 5 110289233-110738956 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 14.4;testis: 16.9" "Cell type enhanced" "Detected in many" "Astrocytes: 154.8;Early spermatids: 130.7;Endometrial ciliated cells: 80.5;Excitatory neurons: 258.9;Inhibitory neurons: 175.0;Respiratory ciliated cells: 114.0;Spermatocytes: 83.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049386 Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA049386: AB_2680739" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (7.27e-2)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.49e-2)" "unprognostic (9.88e-2)" "unprognostic (1.91e-1)" "unprognostic (1.22e-1)" "unprognostic (6.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.32e-5)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (3.14e-4)" "unprognostic (8.96e-2)" 0.6 1.2 2.7 0.2 2.4 0.1 1.1 1.1 1.8 1.1 8.3 0.4 0.5 0.8 1.7 0.6 14.4 1.8 0.7 1.8 2.3 3.7 0.7 1.7 0.4 6.6 7.9 0.7 0.4 2.1 1.3 0.4 6.0 0.9 0.4 3.6 0.6 0.7 0.0 0.4 0.3 0.4 5.1 0.2 0.9 16.9 2.8 0.4 3.8 0.3 0.3 0.3 0.1 5.3 0.4 0.1 1.0 0.3 0.8 1.5 0.2 0.0 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.0 1.6 0.3 0.2 0.8 0.2 1.0 0.1 0.1 0.0 0.0 0.7 0.3 0.1 0.4 0.1 0.2 0.4 1.4 0.0 1.2 0.3 0.3 0.5 0.1 0.5 0.3 0.1 0.1 0.0 0.2 0.1 0.2 1.0 0.0 0.8 1.0 0.1 0.0 0.9 1.6 0.4 0.1 0.0 1.1 0.1 0.0 0.0 2.5 0.9 0.4 0.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.4 1.1 1.8 1.8 2.3 6.6 7.9 6.0 5.1 2.8 5.3 0.6 0.0 5.4 154.8 0.4 0.4 0.9 4.8 1.2 5.0 1.2 0.8 2.4 1.5 11.7 7.3 27.1 0.3 0.0 0.4 9.8 1.3 130.7 80.5 1.4 0.7 1.2 0.8 258.9 0.5 0.1 0.8 0.0 2.3 0.0 0.7 1.1 0.6 0.1 3.3 175.0 0.6 8.2 1.3 0.0 68.0 1.2 0.7 0.0 32.8 0.0 4.5 0.0 54.8 66.1 0.2 0.1 0.7 0.5 0.7 0.4 5.5 114.0 16.9 0.0 1.6 1.8 83.9 4.3 0.1 0.4 0.3 0.2 1.6 0.3 0.6 TMEM233 "DSPB2, IFITMD2" ENSG00000224982 "Transmembrane protein 233" B4DJY2 12 119593774-119643075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 66.6;tongue: 21.2" "Group enriched" "Detected in some" 5 "granulocytes: 79.1;Skeletal myocytes: 77.8" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 22.2;hTERT-RPE1: 9.0;RH-30: 11.8;U-2197: 17.9;U-87 MG: 70.3" "Not detected" "Not detected" "HPA047506, HPA075435" Uncertain Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "HPA047506: AB_10963068, HPA075435: " "unprognostic (1.46e-2)" "unprognostic (1.16e-2)" "unprognostic (1.39e-3)" "unprognostic (1.03e-2)" "unprognostic (1.99e-3)" "unprognostic (1.71e-2)" "unprognostic (5.86e-2)" "unprognostic (1.55e-2)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (4.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.10e-3)" "unprognostic (2.94e-1)" "unprognostic (4.38e-2)" "unprognostic (3.66e-1)" 0.7 0.6 4.6 0.1 6.6 0.0 0.4 1.1 9.0 0.4 1.3 0.2 0.2 0.3 0.2 0.3 0.2 0.5 1.2 4.4 2.5 1.3 0.6 0.9 0.2 1.8 1.4 0.9 0.2 1.3 0.8 0.1 1.8 0.6 0.2 0.2 0.5 0.3 66.6 0.1 0.3 0.4 1.4 0.2 0.3 0.2 3.4 0.9 14.3 21.2 0.2 1.0 0.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 1.7 0.0 22.2 0.0 9.0 0.1 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 6.6 1.1 9.0 4.4 2.5 1.8 1.4 1.8 1.4 3.4 4.4 12.0 3.2 1.1 0.7 0.0 0.0 0.4 0.0 0.0 2.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.9 9.5 0.3 0.1 13.3 0.0 0.0 5.4 8.5 0.0 3.6 0.0 0.4 79.1 5.5 15.4 0.1 0.1 8.4 3.7 0.0 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.5 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.4 0.0 77.8 2.2 3.1 1.0 0.2 0.1 0.1 0.9 9.2 0.0 0.2 TMEM235 ENSG00000204278 "Transmembrane protein 235" A6NFC5 17 78231310-78240987 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 107.8" "Cell type enriched" "Detected in some" 23 "Oligodendrocytes: 107.8" "Cancer enriched" "Detected in single" 15 "glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053939 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA053939: AB_2682316" "unprognostic (1.47e-1)" "unprognostic (6.91e-3)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" 0.0 0.0 41.5 0.0 73.7 0.0 0.0 46.9 59.8 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 42.8 0.0 0.0 0.0 0.0 65.0 60.2 0.0 0.0 0.0 0.3 0.0 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 59.6 0.3 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 73.7 46.9 59.8 40.4 42.8 65.0 60.2 52.2 38.7 59.6 107.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 107.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM238 ENSG00000233493 "Transmembrane protein 238" C9JI98 19 55379244-55384292 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.9;stomach 1: 16.5" "Group enriched" "Detected in many" 4 "Breast glandular cells: 102.2;Breast myoepithelial cells: 233.7;Endometrial ciliated cells: 80.6;Glandular and luminal cells: 104.2" "Cancer enhanced" "Detected in all" "ovarian cancer: 52.1;stomach cancer: 48.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 30.6;CAPAN-2: 18.3;HaCaT: 27.3;RPMI-8226: 19.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.90e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-2)" "unprognostic (4.69e-2)" "unprognostic (1.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.19e-1)" "unprognostic (7.35e-2)" "unprognostic (7.21e-2)" "unprognostic (2.25e-2)" "unprognostic (5.49e-2)" "unprognostic (5.33e-2)" "prognostic favorable (8.84e-6)" "unprognostic (1.78e-3)" "unprognostic (5.55e-2)" "unprognostic (7.91e-3)" "unprognostic (1.17e-3)" 1.1 1.0 0.7 2.5 0.8 1.1 2.4 2.6 1.2 1.7 3.2 15.9 13.9 0.5 0.2 8.8 1.5 0.1 0.3 0.9 0.7 6.7 8.9 3.1 0.8 1.2 1.2 0.4 13.4 1.1 3.1 0.1 1.0 4.4 2.0 0.1 9.2 0.4 1.0 7.2 14.4 0.1 0.7 1.6 16.5 0.3 0.9 0.3 6.2 0.0 0.6 1.9 3.3 0.9 30.6 2.1 0.1 1.7 0.0 0.0 1.7 1.3 0.1 0.0 0.0 1.3 18.3 13.8 5.5 0.1 0.0 27.3 0.5 0.7 0.1 4.0 0.8 0.4 2.6 0.0 0.1 2.9 0.5 0.0 3.7 0.1 0.6 0.2 0.0 2.5 1.8 11.3 0.0 6.8 3.7 1.6 0.8 7.6 9.5 6.8 0.2 19.0 1.2 9.6 9.1 2.9 1.2 14.2 2.1 0.1 10.8 1.7 0.0 0.3 2.4 0.1 0.3 7.5 5.1 3.5 0.1 1.6 0.2 0.0 0.0 0.1 0.4 0.0 1.0 0.6 1.0 0.7 0.0 0.4 0.7 0.6 0.0 0.2 0.0 0.2 1.3 0.1 0.7 0.8 2.6 1.2 0.9 0.7 1.2 1.2 1.0 0.7 0.9 0.9 13.0 0.0 2.4 0.0 20.2 8.5 3.7 0.5 1.2 0.3 102.2 233.7 1.1 27.1 0.5 7.3 0.0 0.0 21.4 29.1 1.9 1.9 0.0 80.6 8.2 2.4 13.8 0.4 0.4 4.3 0.1 2.0 4.1 104.2 0.0 4.5 1.4 13.6 0.3 3.3 0.4 22.8 0.0 2.8 4.9 0.0 0.0 4.3 1.8 0.0 0.7 8.6 2.1 0.0 0.4 3.9 12.9 0.0 16.5 2.3 12.3 1.8 0.5 1.5 0.0 6.3 2.6 0.0 0.0 3.1 26.0 0.0 19.9 2.7 20.3 3.8 TMEM238L LINC00675 ENSG00000263429 "Transmembrane protein 238 like" 17 10794913-10804099 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 37.5;stomach 1: 45.2;urinary bladder: 21.8" "Group enriched" "Detected in some" 5 "Collecting duct cells: 16.5;Theca cells: 4.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "OE19: 6.4;RT4: 4.1" "Not detected" "Not detected" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (7.23e-3)" "unprognostic (1.55e-1)" "unprognostic (3.49e-2)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (2.59e-2)" "unprognostic (2.99e-2)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (9.30e-3)" "unprognostic (6.09e-2)" "unprognostic (1.74e-1)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (3.11e-1)" "unprognostic (7.56e-2)" "unprognostic (1.19e-2)" 0.1 0.1 0.5 1.8 0.6 0.0 1.7 0.4 0.6 1.6 0.0 37.1 18.2 0.1 0.7 5.4 0.4 2.7 0.0 0.4 0.5 2.1 0.8 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.0 0.0 0.5 0.6 37.5 0.0 0.6 3.4 0.0 1.1 16.6 1.3 0.4 0.0 45.2 0.3 0.9 0.0 0.0 0.0 0.4 21.8 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.6 0.4 0.5 0.5 0.5 0.5 0.4 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 TMEM239 ENSG00000198326 "Transmembrane protein 239" Q8WW34 20 2816302-2820284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 115 "testis: 106.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 127.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "HDLM-2: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.12e-3)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 127.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM242 "BM033, C6orf35" ENSG00000215712 "Transmembrane protein 242" Q9NWH2 6 157289025-157323601 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025764 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025764: AB_1845742" "unprognostic (5.42e-3)" "unprognostic (6.02e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (6.24e-2)" "unprognostic (2.21e-3)" "unprognostic (2.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.85e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-3)" "unprognostic (1.28e-1)" "unprognostic (6.50e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" 6.7 9.2 9.2 5.0 9.9 11.0 6.4 9.6 10.6 7.5 8.4 7.3 5.9 7.6 8.0 6.0 5.8 5.0 14.1 10.0 9.1 8.2 10.2 5.4 5.4 8.8 8.4 6.5 5.5 10.7 6.2 6.1 9.0 6.5 6.2 9.5 6.8 5.4 12.1 6.1 5.7 7.9 8.3 5.2 6.5 4.7 9.4 6.0 7.4 11.9 5.8 7.2 6.9 9.3 5.1 4.0 8.3 8.8 15.4 10.0 6.2 9.7 9.1 9.7 10.7 5.3 4.9 7.7 12.5 10.6 13.3 9.0 8.7 8.7 9.9 11.1 14.3 10.9 9.1 10.8 16.0 11.3 8.3 10.2 9.3 6.9 14.1 13.4 11.8 10.3 17.1 10.1 8.7 5.2 6.6 14.9 5.6 3.2 7.8 3.8 5.4 11.1 13.9 4.5 10.9 5.7 8.7 5.8 11.8 7.6 5.9 11.9 9.9 6.7 7.6 14.5 13.0 9.7 10.5 7.3 13.7 13.0 11.2 15.0 19.5 12.4 13.9 16.8 13.4 18.5 14.0 13.9 18.6 19.5 12.1 13.8 3.0 17.1 11.6 29.8 16.7 12.1 9.2 9.9 9.6 10.6 10.0 9.1 8.8 8.4 9.0 8.3 9.4 9.3 28.8 12.8 10.0 7.5 21.6 27.5 18.8 62.2 25.6 25.1 20.3 25.4 51.8 20.0 27.1 22.0 4.2 51.2 28.0 19.6 33.2 49.1 11.7 25.8 32.8 28.0 9.6 40.0 23.0 39.1 53.2 27.5 13.3 28.6 15.8 16.9 25.4 28.5 36.5 38.7 28.3 21.8 32.6 17.3 26.7 6.8 21.1 17.7 42.7 14.0 21.7 26.9 27.8 15.1 22.0 39.6 26.9 26.7 23.7 17.9 32.0 38.2 29.7 30.5 59.2 22.8 36.0 34.7 37.1 24.4 24.3 41.6 24.8 24.6 24.6 16.8 TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 192.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 150.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA014918: AB_2067447" "unprognostic (5.14e-3)" "unprognostic (7.27e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.39e-2)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (4.58e-2)" "unprognostic (2.69e-1)" "unprognostic (6.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-2)" "prognostic favorable (9.13e-4)" 28.6 16.4 16.3 31.0 17.0 28.5 26.7 16.8 20.1 31.9 20.2 19.3 24.8 21.9 38.7 18.2 27.9 22.6 16.2 16.2 16.5 36.6 8.6 52.6 68.1 16.9 16.8 35.4 35.1 20.3 22.4 32.6 16.7 24.9 17.3 5.8 32.0 24.1 5.2 21.0 38.8 16.0 17.8 44.2 27.4 10.9 17.3 27.4 69.8 8.1 80.3 23.0 27.1 18.1 35.7 21.1 20.7 25.8 48.5 54.0 49.7 28.5 42.9 20.9 38.2 29.7 42.1 76.1 61.1 28.7 37.9 33.4 19.8 28.6 27.7 32.5 52.7 1.2 38.5 63.2 38.0 27.7 5.7 36.0 28.3 16.1 32.2 40.0 31.6 39.3 3.6 39.8 28.7 58.7 34.9 4.5 23.4 4.1 28.9 68.0 62.0 105.1 61.0 27.3 22.7 20.4 21.2 43.4 33.0 35.7 16.2 4.9 17.0 35.2 30.9 90.2 25.1 56.1 52.2 150.0 32.2 25.3 21.0 53.3 34.8 23.9 45.3 38.3 65.6 181.9 81.6 57.4 61.5 170.8 135.6 95.5 15.7 67.7 25.6 129.4 79.7 38.8 16.3 17.0 16.8 20.1 16.2 16.5 16.9 16.8 16.7 17.8 17.3 18.1 45.0 25.6 109.4 6.5 192.9 42.7 44.0 55.7 31.9 6.1 40.0 42.4 1.0 34.3 32.9 22.0 39.6 111.8 102.2 8.1 52.8 26.2 139.6 41.6 21.3 41.6 7.3 13.9 14.8 42.5 43.8 44.7 21.9 18.9 2.5 25.6 32.9 3.4 48.9 11.8 13.9 23.5 14.2 66.5 62.4 23.0 83.0 45.6 51.6 22.5 43.7 8.8 50.4 6.6 6.1 24.3 24.5 59.0 144.9 51.4 34.6 70.0 34.6 12.2 46.0 24.6 19.8 16.8 43.2 23.6 38.1 33.5 85.1 29.3 39.7 43.7 TMEM247 ENSG00000284701 "Transmembrane protein 247" A6NEH6 2 46479565-46484425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 21.8" "Group enriched" "Detected in some" 12 "Early spermatids: 443.1;Late spermatids: 400.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "U-266/84: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079482 Enhanced NA NA "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA079482: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 400.3 3.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.0 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 1600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA016495: AB_1848643" "unprognostic (6.74e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (4.64e-2)" "unprognostic (6.67e-3)" "unprognostic (9.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (9.18e-2)" "unprognostic (2.80e-3)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (8.28e-2)" "unprognostic (5.57e-2)" 31.8 39.7 29.2 27.5 30.8 17.8 34.8 25.3 29.0 46.6 57.5 40.8 42.4 44.3 40.6 26.6 45.0 38.6 32.4 32.2 36.1 36.3 49.4 38.7 36.5 27.3 31.0 50.0 40.3 50.0 31.7 34.5 31.0 43.1 41.1 39.0 39.6 40.9 23.1 29.5 37.4 39.2 26.3 34.2 43.6 32.6 40.1 29.5 46.1 21.4 35.0 34.0 32.4 28.0 46.4 53.3 44.2 63.4 98.2 75.0 38.7 55.7 95.1 51.8 55.9 38.9 59.2 46.7 66.3 75.5 70.8 40.8 38.3 45.9 64.0 43.1 28.2 34.2 36.9 45.4 63.5 57.6 45.5 68.0 52.4 43.6 36.1 75.4 68.5 36.1 66.6 30.6 83.4 28.1 54.3 70.5 65.9 47.5 36.1 39.3 51.4 79.3 70.3 35.1 30.7 65.6 49.1 89.0 50.6 65.6 44.8 52.1 63.9 72.4 35.4 48.0 61.9 37.2 45.4 52.1 60.6 62.9 70.5 2.3 4.0 7.7 6.0 4.3 7.2 8.3 6.5 6.4 3.2 8.1 6.3 6.8 5.8 7.3 2.7 8.3 4.7 1.9 29.2 30.8 25.3 29.0 32.2 36.1 27.3 31.0 31.0 26.3 40.1 28.0 55.1 51.3 42.7 14.7 66.2 64.5 53.5 23.6 46.7 18.5 60.6 44.2 25.0 51.5 25.2 53.3 6.2 48.3 75.2 100.8 11.7 37.0 106.2 37.8 34.5 51.7 27.6 45.9 25.8 47.2 81.2 60.9 55.5 35.0 28.5 44.8 58.2 109.9 52.7 18.5 26.4 82.6 16.2 65.7 76.5 172.3 63.6 53.0 49.8 20.6 46.2 96.7 62.8 24.1 27.7 60.2 62.3 65.8 76.5 108.8 64.4 34.3 36.9 12.7 32.9 40.3 47.7 111.5 57.9 42.2 73.9 88.1 64.4 46.4 60.3 98.7 TMEM249 C8orfK29 ENSG00000261587 "Transmembrane protein 249" Q2WGJ8 8 144352219-144354914 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 27.6" "Group enriched" "Detected in some" 9 "Early spermatids: 32.4;Late spermatids: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078901 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA078901: " "unprognostic (2.23e-1)" "unprognostic (8.91e-3)" "unprognostic (1.72e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.03e-4)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (8.44e-2)" "unprognostic (3.21e-1)" "unprognostic (1.13e-7)" "unprognostic (6.56e-3)" "unprognostic (1.62e-2)" "unprognostic (8.44e-3)" "unprognostic (3.46e-2)" 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 27.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.2 0.0 0.0 0.2 0.3 0.4 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.4 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 32.4 0.1 0.2 0.1 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 3.3 1.6 0.3 0.0 0.0 0.0 30.4 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.1 0.0 0.4 0.0 TMEM250 "bA83N9.1, C9orf69" ENSG00000238227 "Transmembrane protein 250" H0YL14 9 136114581-136118875 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 17.1;Extravillous trophoblasts: 21.3;Pancreatic endocrine cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066070 Supported Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA066070: AB_2685608" "unprognostic (2.79e-2)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "prognostic favorable (1.09e-4)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (4.34e-2)" "unprognostic (1.27e-3)" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (6.31e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-2)" "unprognostic (9.33e-3)" "unprognostic (1.09e-2)" "unprognostic (2.41e-2)" "unprognostic (1.64e-1)" 14.9 14.0 18.6 11.6 18.6 4.3 13.5 14.1 20.2 12.8 10.0 20.0 16.7 14.3 7.3 29.1 12.2 6.9 17.4 19.5 12.0 16.3 21.7 13.1 11.4 15.6 13.8 13.2 13.2 8.2 11.9 10.4 16.4 14.7 8.0 2.9 14.0 8.5 28.5 20.8 17.1 7.7 13.3 16.8 15.6 13.0 16.7 8.7 11.0 10.4 8.9 19.5 15.0 16.0 24.9 46.2 17.7 26.5 24.7 22.4 54.9 29.2 20.7 17.3 12.3 26.4 35.5 18.3 33.3 31.5 27.6 62.2 12.6 20.6 5.4 78.8 24.1 15.4 48.3 18.7 34.2 28.2 19.2 20.2 38.8 18.8 19.6 22.3 27.9 18.0 35.1 18.9 15.3 57.3 34.6 22.7 39.2 43.4 49.6 14.0 24.5 30.5 19.0 17.9 30.4 23.1 31.5 21.6 26.4 10.4 19.7 42.1 31.6 30.2 13.3 39.8 32.9 11.0 11.3 10.9 30.4 19.9 29.0 4.3 2.9 1.8 6.2 4.2 4.5 1.8 4.7 5.2 3.0 1.3 2.2 4.1 3.4 3.5 4.2 1.9 2.6 2.1 18.6 18.6 14.1 20.2 19.5 12.0 15.6 13.8 16.4 13.3 16.7 16.0 11.9 6.4 7.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 12.9 11.9 0.0 0.0 1.3 14.7 0.0 17.1 15.2 0.0 3.9 13.1 0.0 9.8 12.6 6.0 0.0 0.0 0.0 10.6 21.3 5.1 0.0 7.0 2.5 14.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 1.3 0.0 0.0 13.2 1.5 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 7.8 5.5 11.5 0.0 0.0 TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 113.5;Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" 16.6 22.9 7.3 6.4 7.8 2.7 16.9 7.9 10.0 15.5 8.2 22.9 10.3 14.2 16.5 13.1 14.7 6.7 25.6 7.6 7.6 33.2 17.2 17.1 8.0 7.7 7.8 14.2 21.2 10.3 19.8 6.9 7.8 25.7 12.5 20.7 19.6 9.2 30.6 13.7 18.1 6.8 7.4 15.9 21.8 8.4 8.1 8.6 17.6 12.4 6.9 17.2 12.8 9.0 11.0 12.1 15.3 16.1 17.2 7.3 9.4 7.9 8.2 12.7 16.2 7.8 11.1 12.1 12.9 7.9 15.9 15.9 17.8 12.6 17.7 9.3 13.4 10.9 8.8 18.3 15.2 16.0 14.7 9.3 14.6 10.0 16.2 6.8 12.2 13.5 9.3 12.0 11.6 52.5 10.2 12.8 8.3 28.0 11.6 4.7 16.0 11.3 16.6 23.6 12.9 13.4 11.7 6.0 36.9 12.4 17.7 11.4 5.0 6.1 10.8 14.6 9.4 9.3 16.0 11.8 11.4 6.1 9.1 6.8 9.7 13.6 3.9 9.4 2.9 4.7 4.6 4.4 8.0 5.5 5.2 5.9 10.5 5.3 13.0 7.3 4.1 4.2 7.3 7.8 7.9 10.0 7.6 7.6 7.7 7.8 7.8 7.4 8.1 9.0 13.4 3.2 14.4 5.2 22.4 23.2 37.9 33.6 13.1 14.8 41.1 39.1 22.5 32.9 22.0 31.3 27.1 36.6 16.5 44.8 113.5 30.3 1.8 33.1 16.3 11.9 15.0 11.3 5.9 26.6 21.1 16.6 20.9 35.7 17.2 15.2 8.9 19.2 110.1 13.5 7.8 36.1 26.4 28.4 20.0 2.3 11.8 39.6 32.0 2.8 16.2 34.8 12.3 5.0 13.8 17.7 23.8 10.9 13.1 43.3 31.7 69.6 17.2 30.6 39.5 13.9 23.2 4.5 17.8 18.1 31.1 27.4 16.1 17.6 30.9 36.4 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.7;ovary: 19.6" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 32.6;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cell line enhanced" "Detected in some" "Karpas-707: 25.3;NTERA-2: 9.5;RPMI-8226: 17.1;SK-MEL-30: 27.7;U-2 OS: 11.8;U-87 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" 4.7 3.3 7.4 1.8 5.8 0.7 3.2 4.8 9.2 11.9 1.7 2.6 0.7 1.9 1.6 2.8 3.8 1.1 1.3 3.8 27.4 1.4 0.6 3.0 3.6 22.7 48.7 19.6 0.4 1.4 3.8 0.2 33.0 1.4 2.3 1.5 1.2 1.8 1.4 2.6 2.3 0.9 19.9 1.7 1.8 0.2 36.8 8.1 0.4 2.7 3.8 1.9 8.5 11.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.2 0.0 0.1 0.3 0.0 2.9 0.0 1.9 0.7 0.7 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 25.3 0.4 0.0 0.0 0.1 9.5 0.0 0.0 0.1 0.0 17.1 0.0 0.0 5.1 0.1 0.5 0.0 27.7 0.3 0.0 0.3 0.0 0.0 11.8 0.0 5.1 0.0 5.2 3.7 29.7 0.0 0.0 0.0 0.3 0.0 2.8 0.1 1.4 0.2 0.2 1.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 7.4 5.8 4.8 9.2 3.8 27.4 22.7 48.7 33.0 19.9 36.8 11.5 0.1 3.2 0.0 1.6 0.0 0.4 0.1 0.1 0.6 1.9 0.2 1.3 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.2 0.0 0.0 4.4 0.0 0.4 0.0 0.3 0.4 0.0 1.3 0.0 4.3 0.0 0.0 1.0 0.7 1.6 0.6 1.6 5.4 1.9 3.7 0.3 0.0 32.6 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 14.6 0.6 0.1 0.1 0.0 1.3 0.1 0.4 0.0 0.0 0.0 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 573.1;Proximal enterocytes: 972.0;Proximal tubular cells: 801.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" 92.2 84.3 63.9 22.2 66.4 36.7 86.7 67.7 73.0 85.6 63.5 72.6 76.3 63.5 48.2 74.7 77.6 24.0 99.8 62.1 65.2 122.4 173.9 51.8 34.5 67.3 64.2 75.4 113.8 42.6 45.9 14.3 67.1 81.5 25.2 15.1 60.3 24.4 67.4 64.3 90.0 17.6 67.6 67.9 91.7 12.4 64.5 30.8 51.5 41.6 28.5 69.7 67.6 72.4 67.0 89.3 47.3 64.3 78.6 99.0 43.0 30.7 43.9 49.4 46.3 36.1 38.0 59.0 54.0 31.2 39.4 56.4 29.9 93.6 35.7 30.5 99.4 37.5 32.0 95.1 54.0 13.0 49.0 87.1 44.2 64.1 53.0 66.4 73.1 63.8 28.9 39.1 64.1 36.5 44.1 42.5 21.4 29.4 58.6 69.9 41.5 68.8 121.2 28.8 5.5 37.9 47.6 36.7 51.2 46.0 66.6 23.4 43.7 22.8 42.7 46.5 39.3 32.6 45.2 31.2 60.2 18.0 44.4 12.9 63.1 14.8 35.7 48.5 44.5 77.4 42.3 41.3 59.7 69.0 48.5 45.2 3.9 39.3 36.3 82.3 46.0 77.8 63.9 66.4 67.7 73.0 62.1 65.2 67.3 64.2 67.1 67.6 64.5 72.4 103.1 44.8 55.8 0.0 134.5 87.4 93.3 100.1 94.4 24.0 212.4 216.9 62.5 131.5 76.9 132.4 8.4 77.2 78.4 162.9 297.4 132.8 6.0 80.2 84.6 85.1 125.3 100.5 0.0 190.8 223.6 83.3 88.7 84.5 68.4 50.3 114.5 573.1 205.5 20.2 0.0 186.6 81.4 164.7 128.2 6.8 137.3 108.4 144.1 0.0 166.7 134.0 88.6 0.0 0.0 171.3 214.0 71.1 173.1 87.3 972.0 801.9 96.3 42.0 59.2 80.2 160.2 10.1 39.1 179.5 134.0 46.7 91.7 64.5 210.0 90.9 TMEM258 "C11orf10, Kud, Kuduk" ENSG00000134825 "Transmembrane protein 258" P61165 11 61768501-61792802 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044602 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "HPA044602: AB_10961423" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (7.49e-2)" "unprognostic (4.99e-3)" "unprognostic (9.95e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.24e-1)" "unprognostic (8.48e-2)" "prognostic favorable (4.37e-4)" "unprognostic (1.34e-3)" "unprognostic (7.39e-2)" "unprognostic (4.75e-3)" "unprognostic (2.59e-2)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.58e-1)" 116.4 158.4 125.5 66.1 128.7 128.4 120.8 130.8 162.2 142.2 123.0 112.4 80.9 116.0 350.1 122.8 123.1 59.3 170.8 122.6 128.7 123.5 160.6 110.0 83.0 130.0 125.6 154.9 300.3 80.5 128.9 80.4 130.3 105.5 107.6 44.0 183.9 88.7 146.7 95.3 99.8 81.5 131.1 124.4 142.8 79.1 126.8 111.7 109.1 120.6 108.9 107.5 111.7 140.1 144.3 254.9 194.9 173.3 329.0 308.4 117.1 113.9 177.1 104.5 124.8 223.5 265.5 103.9 205.9 272.1 196.1 154.8 186.7 222.7 149.1 141.7 168.6 86.8 258.3 347.6 310.7 186.9 96.3 272.5 339.6 137.1 364.8 267.9 210.9 207.4 221.7 394.5 185.4 501.1 131.2 318.8 267.1 315.6 172.9 142.1 144.6 673.0 241.5 243.7 169.3 173.1 103.8 221.7 211.5 179.6 244.5 347.3 108.0 129.2 111.7 166.1 78.3 248.6 201.7 173.6 183.8 112.6 135.7 507.9 225.6 287.6 169.5 200.4 216.5 233.2 198.8 190.1 177.8 187.1 167.1 166.7 182.4 151.7 204.4 496.4 236.8 244.9 125.5 128.7 130.8 162.2 122.6 128.7 130.0 125.6 130.3 131.1 126.8 140.1 211.3 102.5 224.1 6.8 323.6 228.9 220.5 794.5 170.8 41.3 525.1 608.3 491.3 403.2 445.9 318.2 18.8 409.5 279.8 306.2 295.4 534.8 234.4 369.2 304.7 254.8 311.1 197.7 7.4 654.4 667.7 314.8 210.5 305.6 226.7 261.8 335.2 572.9 461.4 37.0 8.2 631.5 441.5 401.7 396.9 142.8 335.5 265.7 569.2 3.7 430.0 418.6 270.8 6.0 25.8 469.4 432.6 214.4 821.3 296.6 392.2 553.8 470.9 73.9 170.9 192.3 248.5 399.4 433.8 297.4 279.0 508.0 245.2 135.3 442.1 274.9 TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.2;Endometrial stromal cells: 5.4;Excitatory neurons: 5.3;Hepatic stellate cells: 4.6;Inhibitory neurons: 4.8;Kupffer cells: 12.2;Late spermatids: 5.6;Theca cells: 15.0" "Group enriched" "Detected in some" 4 "breast cancer: 2.5;endometrial cancer: 1.0;prostate cancer: 1.8;renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.7;fHDF/TERT166: 1.1;HSkMC: 2.0;HUVEC TERT2: 1.5;MOLT-4: 2.3" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "unprognostic (7.34e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.41e-2)" "unprognostic (5.38e-2)" "unprognostic (5.24e-2)" "unprognostic (2.29e-5)" "unprognostic (2.55e-2)" "unprognostic (1.51e-2)" "unprognostic (8.53e-2)" "unprognostic (1.95e-1)" 0.5 0.5 1.3 0.9 1.4 0.1 5.2 0.3 1.1 2.3 0.2 0.7 1.4 4.0 0.1 0.5 0.4 1.0 0.2 1.1 0.8 2.2 2.5 1.4 0.7 0.8 1.0 0.5 0.0 1.4 0.2 1.5 0.4 2.6 0.9 0.0 0.0 2.4 0.8 0.0 0.8 2.0 0.5 8.8 0.2 3.6 1.5 2.1 0.4 0.2 0.2 0.7 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.8 0.1 0.0 4.7 0.4 0.6 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.5 0.0 0.5 1.5 0.5 0.0 0.0 0.1 0.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.3 1.1 1.1 0.8 0.8 1.0 0.4 0.5 1.5 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.7 5.4 1.7 0.0 0.0 5.3 0.0 0.0 1.4 0.0 1.6 0.0 0.1 4.6 0.2 0.3 0.0 4.8 0.0 0.0 12.2 0.0 5.6 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 1.2 0.5 0.2 0.0 0.1 0.0 0.1 15.0 0.0 0.0 TMEM262 ENSG00000187066 "Transmembrane protein 262" E9PQX1 11 65084979-65089375 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 21.1" "Cell type enriched" "Detected in some" 11 "Early spermatids: 179.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (4.36e-2)" "unprognostic (2.77e-1)" "unprognostic (1.78e-3)" "unprognostic (1.62e-1)" "unprognostic (1.61e-1)" "unprognostic (1.71e-4)" "unprognostic (1.85e-5)" "unprognostic (3.28e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.19e-3)" "unprognostic (7.18e-3)" "unprognostic (7.13e-9)" "unprognostic (9.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.3 0.2 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 179.5 0.3 0.2 0.2 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 16.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.4 0.2 1.1 1.2 0.5 0.3 0.4 0.5 0.1 0.1 0.1 TMEM267 "C5orf28, FLJ21657" ENSG00000151881 "Transmembrane protein 267" Q0VDI3 5 43444252-43483893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 20.2;Collecting duct cells: 16.5;Cytotrophoblasts: 26.3;Distal tubular cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059946, HPA072991" Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA059946: AB_2684175, HPA072991: " "unprognostic (8.20e-2)" "unprognostic (2.02e-2)" "unprognostic (7.60e-2)" "unprognostic (8.11e-3)" "unprognostic (1.57e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.82e-2)" "unprognostic (4.77e-3)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.35e-1)" "unprognostic (1.07e-2)" "unprognostic (4.40e-3)" 7.6 7.0 5.7 8.8 5.4 4.9 15.1 5.5 6.2 10.9 7.1 8.4 7.6 8.4 11.9 8.1 8.6 7.7 6.0 5.3 6.5 9.8 7.2 7.6 10.4 5.7 6.6 7.7 7.6 10.7 5.7 6.7 6.5 9.0 9.9 8.1 8.6 9.9 6.2 10.4 6.5 9.6 6.2 8.6 9.9 7.3 5.7 9.2 38.2 3.7 9.6 8.6 6.7 6.4 20.0 18.0 9.5 21.2 17.2 34.8 10.8 28.0 17.3 14.9 10.8 7.9 41.7 21.9 37.7 28.9 15.8 16.3 9.2 12.6 21.3 26.7 14.8 12.9 37.2 8.8 32.0 26.5 17.9 28.9 35.3 22.3 31.7 15.0 16.7 26.3 17.1 39.9 32.8 17.1 14.5 15.3 4.4 20.4 17.4 9.9 23.5 27.3 18.7 20.1 13.2 9.3 56.1 31.5 27.9 8.7 46.0 18.4 21.9 24.0 19.4 14.9 14.1 17.0 26.5 21.6 18.1 37.3 21.6 16.6 11.1 4.4 15.1 13.5 22.3 14.5 20.2 15.9 12.7 13.4 20.3 16.6 1.9 18.9 16.0 9.8 17.5 14.3 5.7 5.4 5.5 6.2 5.3 6.5 5.7 6.6 6.5 6.2 5.7 6.4 9.7 6.4 3.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 20.2 13.2 0.0 0.0 1.8 16.5 0.0 26.3 6.3 0.0 27.4 13.8 0.0 8.4 9.1 2.6 0.0 0.0 0.0 13.6 10.2 4.5 0.0 9.2 2.5 6.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.9 0.0 0.0 13.7 6.6 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 10.5 3.7 6.6 0.0 0.0 TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 10.3;Breast glandular cells: 8.8;Endometrial stromal cells: 8.9;Glandular and luminal cells: 8.8;Granulosa cells: 9.6;Hofbauer cells: 8.9;monocytes: 19.1;Syncytiotrophoblasts: 8.8;Theca cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 7.3 7.7 11.0 6.9 12.7 3.6 7.5 2.9 16.6 6.5 6.4 6.9 3.4 6.8 6.3 4.3 4.7 3.7 3.3 14.4 6.1 3.3 5.3 5.2 9.5 4.4 5.3 8.5 4.7 14.1 4.1 4.8 5.3 12.2 5.4 4.5 8.9 6.5 4.6 4.2 6.3 6.8 5.3 13.3 7.2 3.9 6.5 8.6 6.2 4.3 9.4 6.3 5.1 11.3 4.7 7.1 3.8 8.2 10.1 7.6 2.9 4.3 7.9 6.0 6.1 5.1 2.0 19.5 3.5 4.8 17.0 8.1 7.4 3.7 5.2 9.9 4.6 6.5 5.8 4.0 17.9 13.6 3.0 6.7 6.5 7.8 8.4 7.7 4.1 24.9 12.3 51.5 4.4 13.6 15.4 4.5 9.8 6.0 7.8 17.4 4.5 17.7 3.5 3.4 12.5 8.4 14.4 18.8 41.3 2.4 25.2 12.2 2.5 6.0 6.8 2.3 8.3 27.8 27.5 20.7 3.1 11.4 11.0 0.3 1.3 0.2 0.6 1.0 0.2 1.3 0.7 0.4 0.7 2.2 0.9 0.8 1.0 0.8 1.0 4.7 0.1 0.5 11.0 12.7 2.9 16.6 14.4 6.1 4.4 5.3 5.3 5.3 6.5 11.3 1.7 0.0 10.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 5.2 0.0 0.0 1.3 0.0 0.0 4.7 3.0 0.0 0.0 1.4 0.0 5.0 8.9 0.5 0.0 0.0 0.0 4.6 1.2 1.3 0.0 8.8 0.0 9.6 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 19.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 1.9 4.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.8 1.1 9.7 0.0 0.0 TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 37.8;dendritic cells: 10.1;Hofbauer cells: 82.9;Macrophages: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.0" "Cell line enhanced" "Detected in some" "HDLM-2: 214.8;HEL: 51.7;K-562: 101.4;U-266/84: 38.3;U-87 MG: 102.2;U-937: 91.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058166 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" 31.5 3.0 15.1 17.2 22.1 4.0 27.5 23.0 27.1 15.1 13.4 12.8 8.8 13.7 6.1 8.4 12.8 18.3 28.0 15.2 18.2 6.0 9.5 27.1 22.2 25.0 22.8 3.9 4.0 14.4 3.3 10.9 25.0 8.2 14.2 1.1 9.8 7.8 8.5 7.3 24.3 20.9 18.9 29.8 8.9 1.9 20.5 7.8 10.2 16.5 23.4 14.4 12.7 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 214.8 0.0 51.7 0.0 0.0 0.0 0.5 21.9 0.0 0.0 0.0 0.0 0.0 1.4 0.2 101.4 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.1 0.0 38.3 0.1 102.2 91.6 0.0 24.9 4.2 269.0 22.9 1.4 36.5 35.9 13.8 22.0 19.8 18.5 0.7 6.1 19.4 0.2 0.7 0.6 11.2 11.5 15.1 22.1 23.0 27.1 15.2 18.2 25.0 22.8 25.0 18.9 20.5 30.7 37.8 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.8 0.0 0.8 10.1 0.0 0.0 0.1 0.0 1.1 0.2 9.4 0.0 0.0 0.0 0.0 0.7 0.5 0.0 2.0 0.0 0.0 0.0 0.0 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 5.6 0.0 0.0 0.0 TMEM30A "C6orf67, CDC50A, FLJ10856" ENSG00000112697 "Transmembrane protein 30A" Q9NV96 6 75252924-75284948 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014561 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA014561: AB_10601823" "unprognostic (2.00e-1)" "unprognostic (2.00e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-2)" "unprognostic (3.48e-1)" "unprognostic (1.02e-2)" "unprognostic (1.11e-1)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (4.80e-2)" "unprognostic (1.88e-1)" "unprognostic (5.06e-2)" "unprognostic (7.12e-2)" "unprognostic (8.96e-2)" "unprognostic (1.00e-1)" 62.9 57.0 60.3 59.1 70.2 53.7 54.0 65.2 67.5 61.3 72.8 64.7 43.9 62.0 50.2 58.1 47.4 60.0 45.3 67.2 73.5 77.3 99.6 91.7 53.5 63.3 64.5 47.6 70.8 96.2 47.6 48.5 64.6 64.7 70.8 57.0 55.2 58.6 29.2 38.3 46.4 79.1 73.5 62.1 59.4 28.8 69.5 47.6 84.5 40.4 60.9 66.4 34.8 82.1 54.2 60.6 91.5 77.6 228.2 212.0 76.3 217.9 171.3 82.3 128.2 56.3 129.1 61.9 148.3 194.8 82.7 62.4 41.5 120.4 211.5 84.9 63.8 60.4 55.1 56.7 129.2 73.7 104.6 197.2 116.5 116.9 63.7 175.2 262.4 59.1 59.4 107.8 158.4 37.2 27.1 54.2 32.7 46.1 46.7 44.4 65.6 78.5 315.3 131.1 64.9 62.9 111.9 52.8 74.9 105.8 58.6 224.8 234.5 103.8 116.9 65.6 153.3 90.3 136.1 27.9 81.7 137.2 165.7 44.5 85.8 59.0 37.1 84.7 44.8 27.1 37.3 36.7 78.6 22.6 34.8 34.5 138.3 42.5 87.5 33.2 53.0 61.5 60.3 70.2 65.2 67.5 67.2 73.5 63.3 64.5 64.6 73.5 69.5 82.1 73.2 163.5 132.5 7.5 38.8 71.2 33.7 67.6 42.1 24.5 53.1 27.6 43.8 40.0 96.1 66.2 45.9 39.6 51.0 67.6 11.7 51.0 11.1 46.7 57.0 68.0 36.2 20.8 15.8 111.2 52.1 65.7 43.3 76.0 39.8 31.4 66.0 79.1 54.3 20.2 14.5 44.3 54.9 89.3 79.1 9.5 45.4 57.8 48.0 10.3 62.4 40.7 35.0 17.1 15.6 101.6 38.5 62.4 55.8 80.9 31.1 33.2 95.2 24.0 32.9 56.1 77.2 45.0 21.2 41.8 78.3 94.4 43.3 62.5 28.8 65.9 TMEM30B CDC50B ENSG00000182107 "Transmembrane protein 30B" Q3MIR4 14 61277370-61281761 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 124.0;Prostatic glandular cells: 101.1;Urothelial cells: 131.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 68.7;CAPAN-2: 54.4;HaCaT: 31.7;HBEC3-KT: 39.0;hTCEpi: 29.1;MCF7: 44.6;RT4: 94.9;T-47d: 30.4" "Not detected" "Not detected" HPA043162 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043162: AB_10796688" "unprognostic (4.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.47e-2)" "unprognostic (2.01e-1)" "unprognostic (6.20e-2)" "unprognostic (2.45e-3)" "unprognostic (3.43e-2)" "unprognostic (9.10e-2)" "unprognostic (2.20e-1)" "unprognostic (5.10e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.89e-5)" "unprognostic (2.21e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (1.85e-1)" 3.9 1.6 0.5 3.7 0.7 0.4 14.8 0.5 1.0 16.4 0.9 29.1 43.3 3.8 28.2 14.1 15.2 23.9 2.0 0.3 0.7 12.3 12.3 14.5 1.2 0.6 0.5 2.5 35.7 59.1 18.2 5.7 0.5 21.9 26.1 0.3 27.7 13.4 1.2 8.6 34.4 1.7 0.5 0.7 42.2 2.6 0.6 5.3 50.0 1.9 4.4 16.1 9.3 0.4 68.7 0.2 0.0 0.0 6.7 1.6 0.1 0.1 0.0 0.0 0.0 11.6 54.4 0.0 0.1 0.0 0.0 31.7 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 44.6 0.0 0.1 0.6 28.2 1.6 0.0 1.5 0.2 0.0 94.9 11.2 0.1 0.8 25.6 0.1 1.9 30.4 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.7 0.5 1.0 0.3 0.7 0.6 0.5 0.5 0.5 0.6 0.4 0.6 28.9 31.9 0.0 0.6 64.9 124.0 19.5 61.5 0.0 32.2 16.5 1.9 47.1 24.5 40.5 0.0 28.0 1.1 90.8 13.7 24.8 0.9 23.8 3.9 3.9 23.4 0.0 0.0 37.2 11.4 5.5 62.7 45.3 2.5 0.7 4.2 14.1 2.0 0.0 0.0 73.1 20.3 1.0 6.8 1.6 8.7 1.5 5.4 1.0 0.6 2.9 2.1 0.0 0.1 31.9 75.3 79.0 0.4 101.1 73.6 1.0 22.7 0.3 13.1 2.4 5.4 5.9 3.6 43.3 63.6 35.8 3.6 0.9 64.7 131.9 TMEM31 MGC39655 ENSG00000179363 "Transmembrane protein 31" Q5JXX7 X 103710909-103714032 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 110.1" "Cell type enriched" "Detected in some" 5 "Late spermatids: 3288.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.8;BEWO: 4.3;MCF7: 6.4;NTERA-2: 1.8;U-937: 2.4" "Low region specificity" "Detected in all" HPA052760 Approved "Nucleoli fibrillar center" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "HPA052760: " "unprognostic (9.42e-5)" "unprognostic (1.46e-2)" "unprognostic (1.18e-1)" "unprognostic (7.51e-2)" "unprognostic (7.75e-3)" "unprognostic (1.22e-2)" "unprognostic (2.43e-1)" "unprognostic (4.50e-2)" "unprognostic (1.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.39e-2)" "unprognostic (3.77e-1)" "unprognostic (5.91e-5)" "unprognostic (1.75e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (4.68e-2)" 0.4 0.2 2.1 0.1 2.4 0.0 0.6 2.1 3.3 1.4 1.6 0.3 0.0 0.6 0.5 0.1 1.0 0.2 0.3 2.1 2.3 0.7 0.3 0.3 0.2 2.3 2.2 1.7 0.2 1.3 0.9 0.9 2.4 0.6 0.0 0.2 0.2 0.3 0.9 0.4 0.2 0.1 2.2 0.4 0.2 110.1 2.4 0.3 0.3 0.0 0.0 0.4 0.5 2.7 0.0 0.0 1.8 0.1 0.1 0.0 4.3 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.2 0.0 1.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.2 6.4 0.1 1.2 1.8 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.5 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.1 2.4 2.1 3.3 2.1 2.3 2.3 2.2 2.4 2.2 2.4 2.7 0.3 0.0 0.0 0.0 0.0 0.8 0.7 0.2 0.0 0.0 0.4 1.5 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 641.3 10.1 0.4 1.1 0.0 0.0 0.2 0.7 8.6 0.6 0.0 0.2 0.0 1.1 0.7 0.2 0.4 0.0 0.1 0.1 0.0 0.3 0.3 3288.8 13.4 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.1 0.0 7.5 0.0 0.3 0.0 0.2 0.0 0.0 13.1 0.3 0.3 19.6 12.1 0.0 0.3 2.9 0.0 0.2 0.0 0.2 TMEM33 "FLJ10525, Pom33" ENSG00000109133 "Transmembrane protein 33" P57088 4 41935129-41960803 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075863 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA075863: " "unprognostic (7.14e-2)" "unprognostic (9.25e-3)" "unprognostic (1.59e-2)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" "unprognostic (2.04e-1)" "unprognostic (3.94e-2)" "unprognostic (5.45e-2)" "unprognostic (2.09e-1)" "unprognostic (1.16e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.70e-2)" "unprognostic (4.20e-1)" "unprognostic (9.35e-3)" "unprognostic (2.36e-2)" 12.4 16.1 8.0 19.4 10.5 14.9 16.0 13.1 11.4 11.4 16.0 18.7 21.1 11.1 25.5 21.2 12.3 17.2 10.5 9.6 12.8 24.2 39.9 15.1 17.0 15.5 13.5 10.5 18.2 30.1 11.0 20.0 14.7 17.2 21.3 13.0 17.9 11.8 8.4 11.9 16.9 11.3 14.1 13.9 19.1 9.9 12.1 14.9 23.8 12.4 20.1 21.8 10.8 18.8 36.9 42.4 36.7 51.3 46.7 31.8 44.9 49.5 53.9 41.5 47.5 52.4 123.4 64.8 74.7 41.5 85.5 57.4 124.4 65.0 56.1 17.1 26.2 80.7 49.7 45.9 54.4 108.7 67.6 33.4 69.0 52.5 78.3 26.5 32.7 37.3 86.8 24.7 57.4 32.6 96.5 67.9 67.2 58.1 50.0 42.7 57.8 51.6 58.2 53.5 40.8 58.4 40.5 38.0 62.4 35.3 42.9 37.4 53.0 48.3 65.0 48.9 89.5 44.5 76.9 77.4 51.7 88.4 71.2 41.2 32.1 21.7 14.9 31.0 17.6 13.0 15.3 14.2 22.9 12.0 13.6 15.0 43.2 16.5 35.2 17.9 19.0 16.4 8.0 10.5 13.1 11.4 9.6 12.8 15.5 13.5 14.7 14.1 12.1 18.8 25.1 60.9 34.3 20.9 25.0 73.3 35.7 42.4 24.5 19.2 36.9 16.4 18.0 27.1 40.5 55.2 16.7 56.3 35.2 58.9 23.5 44.6 2.9 26.9 31.2 25.9 35.0 25.0 33.6 38.1 49.3 30.5 36.2 33.4 38.7 23.1 24.7 84.4 57.3 28.6 32.8 40.4 34.6 67.5 51.0 4.7 20.2 55.7 56.9 11.2 55.9 33.9 16.5 32.6 40.3 54.1 47.4 23.3 32.5 73.7 41.6 41.1 29.7 20.4 26.3 26.5 55.6 31.0 28.7 47.5 66.9 133.1 28.3 39.7 43.0 64.5 TMEM38A "MGC3169, TRIC-A" ENSG00000072954 "Transmembrane protein 38A" Q9H6F2 19 16661139-16690023 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 581.3;tongue: 260.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Cone photoreceptor cells: 85.5;Excitatory neurons: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 36.9;eosinophil: 12.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.9" "Cell line enhanced" "Detected in many" "Daudi: 16.1;OE19: 15.2;U-266/70: 15.6;U-698: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048100, HPA050463" Enhanced Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA048100: , HPA050463: AB_2681137" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-1)" "unprognostic (2.99e-1)" "unprognostic (3.49e-1)" "prognostic favorable (2.78e-5)" "unprognostic (2.94e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "prognostic favorable (2.99e-10)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (4.50e-3)" "unprognostic (1.96e-2)" 2.1 4.1 10.5 1.3 15.4 5.8 2.3 13.3 15.9 1.9 52.4 2.9 1.9 1.3 18.0 9.2 3.4 0.9 26.1 10.8 16.1 5.7 7.6 4.5 1.5 10.7 14.3 2.4 2.1 4.4 7.4 0.6 11.2 7.0 2.7 10.0 9.3 5.0 581.3 1.8 2.0 1.4 10.2 1.6 14.7 3.9 16.0 2.9 2.5 260.0 2.3 1.7 1.3 11.3 4.1 0.8 1.0 6.1 3.3 0.3 0.5 1.4 0.8 0.9 1.9 1.3 5.8 16.1 2.4 0.3 5.3 3.3 8.1 1.7 0.9 1.1 2.4 0.0 2.5 1.3 0.9 0.1 0.2 1.4 6.2 1.1 0.7 4.6 0.4 2.9 0.1 1.5 0.6 6.3 0.2 1.7 1.5 15.2 9.4 8.5 1.4 4.4 5.8 3.0 9.9 6.9 4.4 0.5 2.1 0.5 3.0 1.3 0.0 1.2 2.8 3.7 0.7 15.6 12.2 27.1 1.4 9.6 1.2 36.9 4.2 12.3 0.0 1.6 0.0 4.6 0.5 0.1 0.4 6.0 0.1 0.1 2.4 3.5 1.0 0.8 0.8 1.0 10.5 15.4 13.3 15.9 10.8 16.1 10.7 14.3 11.2 10.2 16.0 11.3 2.8 3.2 1.5 18.3 2.3 1.1 3.5 6.7 3.4 30.7 3.9 2.2 25.9 1.5 3.0 0.0 85.5 0.1 0.6 1.7 1.9 3.6 0.1 1.4 0.6 4.5 4.2 0.0 31.0 2.5 0.1 3.0 17.3 1.4 0.0 2.2 9.7 9.2 0.4 13.5 24.0 7.6 14.2 4.3 1.2 0.9 10.5 0.9 3.6 3.7 0.9 13.9 0.0 7.5 3.1 10.8 1.1 22.6 2.9 3.4 0.4 1.2 1.8 9.5 0.0 25.4 3.9 0.9 1.3 3.3 0.3 0.1 0.6 2.1 2.7 1.3 TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.4;tongue: 62.1" "Cell type enhanced" "Detected in many" "Early spermatids: 267.0;Late spermatids: 488.4;Spermatocytes: 157.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "HPA018465: AB_1858116" "unprognostic (3.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-2)" "unprognostic (3.11e-3)" "unprognostic (1.88e-2)" "unprognostic (3.54e-2)" "unprognostic (5.82e-3)" "unprognostic (5.80e-2)" "prognostic favorable (7.96e-4)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (3.89e-3)" "unprognostic (9.98e-2)" 7.6 14.0 6.2 7.1 11.6 19.1 4.7 19.5 9.2 7.6 6.3 12.5 6.4 8.3 17.3 7.2 7.2 6.8 30.7 7.4 12.9 29.2 15.3 5.7 8.1 8.3 8.4 18.3 4.9 9.2 5.8 4.6 10.6 8.0 11.8 10.4 4.0 6.8 77.4 6.0 10.7 8.1 5.9 6.3 6.7 28.6 9.0 4.9 28.8 62.1 5.1 5.0 4.0 19.6 16.7 25.6 19.6 30.9 110.5 24.3 40.8 23.4 15.3 22.6 23.3 40.0 22.5 38.4 11.8 8.5 36.4 11.6 28.4 13.5 24.4 29.0 37.8 15.8 16.2 24.7 15.1 48.1 32.7 23.0 11.8 15.5 21.6 7.1 9.1 26.6 84.3 33.2 14.0 46.4 33.6 14.5 15.1 48.7 27.1 22.3 61.4 18.4 10.3 13.2 34.1 8.3 24.2 39.4 17.9 13.0 49.2 33.5 4.9 20.5 20.2 78.9 24.7 40.7 109.8 19.1 38.2 52.2 41.7 15.6 20.2 53.8 13.2 29.6 17.7 56.6 18.3 15.8 23.3 56.6 38.9 24.9 3.1 28.2 26.8 51.7 18.0 24.2 6.2 11.6 19.5 9.2 7.4 12.9 8.3 8.4 10.6 5.9 9.0 19.6 9.2 0.0 2.7 7.5 27.8 30.3 24.9 6.2 15.9 12.9 8.9 3.9 55.5 15.7 8.4 25.8 29.2 12.0 16.4 19.1 66.5 8.9 267.0 2.2 7.2 9.9 31.8 7.2 12.4 6.9 19.0 24.2 9.2 3.0 15.8 11.3 3.6 24.4 30.9 11.8 28.6 12.9 18.3 7.9 33.2 488.4 85.1 21.4 32.0 6.5 18.3 30.6 3.1 65.4 30.6 6.3 12.2 44.8 20.2 55.1 10.9 47.0 7.6 12.3 118.3 18.2 58.1 157.8 47.6 13.0 32.7 21.2 13.8 39.7 19.0 20.2 TMEM39A "FLJ10902, SUSR2" ENSG00000176142 "Transmembrane protein 39A" Q9NV64 3 119428949-119468830 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039140 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Vesicles "HPA039140: AB_10673303" "unprognostic (2.16e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-2)" "unprognostic (6.86e-2)" "unprognostic (1.56e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (9.68e-2)" "unprognostic (6.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (4.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.88e-1)" "unprognostic (6.41e-2)" 12.4 10.5 2.2 14.4 4.3 12.9 10.2 4.1 3.5 19.5 10.9 9.0 10.0 13.2 10.9 9.0 11.7 12.6 11.1 2.2 3.1 6.4 13.0 12.4 10.0 4.0 3.4 13.1 28.4 12.8 15.4 18.1 4.3 9.1 9.3 5.0 13.3 14.3 7.2 8.8 8.0 9.7 3.1 9.2 9.8 7.8 4.7 12.1 16.6 11.9 13.6 14.4 10.5 6.2 28.3 15.1 24.1 17.4 56.1 54.2 24.1 26.4 54.3 37.2 50.0 26.1 21.2 12.0 27.4 28.7 37.9 28.7 29.3 12.1 38.0 12.6 11.2 15.5 13.5 25.4 37.9 27.1 23.4 29.7 20.5 25.9 61.5 37.5 23.6 18.5 16.1 35.5 19.6 14.1 13.7 7.0 20.5 29.8 31.5 16.5 11.3 25.7 9.2 10.7 10.7 15.8 26.6 15.2 33.4 17.3 14.8 23.8 18.5 20.2 17.2 13.8 17.3 39.5 12.5 28.5 27.6 18.2 26.8 12.7 10.9 7.3 11.7 5.8 11.9 7.7 7.1 9.6 12.3 9.0 5.6 6.1 3.8 11.9 4.6 17.3 8.9 9.4 2.2 4.3 4.1 3.5 2.2 3.1 4.0 3.4 4.3 3.1 4.7 6.2 8.5 9.6 15.8 9.8 14.3 22.8 16.0 21.8 8.6 4.7 14.6 10.8 10.8 7.2 16.2 7.3 6.2 26.5 24.7 7.4 5.9 11.6 22.8 8.2 26.3 10.8 10.8 9.0 12.4 14.2 57.6 28.9 13.3 17.9 1.3 13.5 7.9 12.0 13.3 1.7 14.0 18.3 6.1 15.0 54.9 6.8 17.1 17.8 10.6 12.2 31.0 3.9 9.2 25.1 21.8 10.2 6.6 13.2 57.8 20.6 8.0 3.0 14.9 6.4 6.6 15.9 25.2 26.1 18.5 9.6 21.7 59.8 17.4 9.4 11.1 20.4 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM41B KIAA0033 ENSG00000166471 "Transmembrane protein 41B" Q5BJD5 11 9280654-9314636 "Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 108.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014946 Uncertain Approved Peroxisomes NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Peroxisomes "HPA014946: AB_2205037" "unprognostic (1.21e-1)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.18e-6)" "unprognostic (6.18e-2)" "unprognostic (9.37e-3)" "unprognostic (4.90e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (8.18e-2)" 6.0 7.6 9.9 7.2 11.0 11.1 8.8 12.5 15.1 5.3 8.9 11.6 17.6 5.4 9.9 8.0 4.9 7.4 8.8 9.5 11.5 11.6 18.8 14.7 8.9 12.8 12.2 4.7 9.6 10.2 3.0 11.4 12.0 11.7 9.5 8.3 9.7 6.1 5.1 9.7 17.1 3.3 12.8 6.8 12.1 8.1 11.6 9.2 15.7 5.0 7.9 7.8 3.4 15.9 34.1 25.5 17.3 18.4 17.8 25.0 47.6 31.5 24.6 14.3 26.3 17.9 108.8 13.2 26.2 18.8 28.5 42.0 19.8 16.4 18.4 20.9 19.4 12.0 21.3 21.1 24.5 11.5 14.2 20.1 23.5 14.5 17.5 18.0 13.0 16.2 25.5 32.8 29.3 11.2 16.0 12.6 50.1 18.8 17.3 12.1 23.9 18.7 25.6 32.2 5.6 20.7 26.1 23.7 26.4 22.5 20.4 15.8 17.9 16.7 21.1 28.9 17.3 9.3 17.6 22.5 18.4 8.0 14.6 9.9 1.4 5.5 5.5 1.7 6.7 7.0 4.1 6.9 1.7 5.3 8.2 10.4 3.5 9.5 1.7 8.5 4.1 3.4 9.9 11.0 12.5 15.1 9.5 11.5 12.8 12.2 12.0 12.8 11.6 15.9 21.6 48.1 77.1 32.3 27.9 76.0 57.8 48.5 42.7 36.7 36.4 21.0 21.3 34.3 44.3 31.3 66.7 44.6 34.8 58.0 7.9 30.6 1.3 48.5 31.5 20.1 39.8 29.0 47.3 39.4 60.5 29.0 22.4 89.2 17.1 24.8 21.4 55.4 22.7 20.2 52.1 42.3 36.7 18.9 44.6 2.0 18.0 24.7 19.6 26.2 23.4 24.0 22.6 37.2 69.3 57.9 40.3 13.9 26.6 58.4 56.0 17.2 34.2 38.4 19.7 37.9 25.4 50.9 44.6 47.0 63.6 56.1 28.3 31.3 33.8 77.0 TMEM50B C21orf4 ENSG00000142188 "Transmembrane protein 50B" P56557 21 33432485-33479974 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034199, HPA068995" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli fibrillar center" "CAB034199: AB_2205160, HPA068995: AB_2686066" "unprognostic (3.22e-1)" "unprognostic (5.93e-2)" "unprognostic (7.82e-2)" "unprognostic (6.14e-2)" "unprognostic (1.26e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.24e-2)" "prognostic favorable (3.33e-4)" "unprognostic (8.65e-2)" "unprognostic (3.36e-2)" "unprognostic (1.85e-2)" "unprognostic (3.54e-2)" "unprognostic (9.58e-3)" "unprognostic (3.41e-3)" "unprognostic (8.28e-2)" "unprognostic (3.47e-3)" "unprognostic (3.32e-3)" 23.4 26.9 17.3 15.5 13.4 9.3 26.4 13.8 20.3 25.3 22.8 20.8 22.4 22.1 55.1 19.9 27.4 29.5 24.7 13.4 15.5 36.0 15.6 24.2 15.4 14.9 20.7 33.6 12.3 35.1 15.0 17.0 16.1 30.8 19.9 28.2 15.8 48.8 19.9 14.5 21.2 22.1 15.0 16.0 23.2 16.0 22.6 13.8 89.3 22.1 15.1 29.7 15.7 14.3 25.7 5.7 10.4 15.5 55.7 40.4 5.4 20.5 27.4 16.8 10.8 6.3 22.9 14.2 21.6 20.3 21.2 10.6 14.2 14.4 12.2 17.3 11.9 28.5 4.0 13.9 25.4 20.7 17.6 20.3 14.0 13.0 10.2 28.4 20.7 15.4 20.1 28.9 21.8 15.9 15.6 21.9 4.6 45.5 5.3 7.9 19.6 25.0 30.4 17.8 8.9 12.1 23.7 29.2 24.5 6.1 34.0 26.7 18.0 11.2 9.1 15.5 8.3 29.4 49.7 18.9 10.5 31.4 19.9 14.7 18.3 43.6 18.1 19.6 18.5 13.4 22.0 20.8 24.8 17.0 24.8 22.7 3.6 19.6 23.3 26.5 35.4 21.2 17.3 13.4 13.8 20.3 13.4 15.5 14.9 20.7 16.1 15.0 22.6 14.3 69.7 28.9 59.4 29.7 44.5 74.1 94.0 55.2 48.9 53.0 61.5 46.0 46.7 55.8 49.3 82.8 108.4 33.9 50.5 46.7 27.4 37.9 58.1 52.6 42.6 60.7 21.6 43.1 23.9 31.0 46.4 62.0 39.8 38.4 29.8 36.1 94.2 55.4 37.9 43.7 46.2 53.1 61.1 33.6 74.1 39.2 71.4 35.4 83.6 33.7 29.7 72.7 50.4 26.2 44.8 28.0 38.2 119.6 57.8 128.9 68.3 56.5 83.6 86.1 98.6 45.0 52.2 190.4 114.0 37.8 93.6 41.3 55.2 22.9 46.5 126.7 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA018216: AB_2205185, HPA019173: AB_1858129" "unprognostic (4.43e-2)" "unprognostic (3.10e-2)" "unprognostic (8.04e-2)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (1.63e-1)" 8.9 12.9 5.8 8.2 6.5 10.9 13.1 13.2 8.4 10.3 14.5 13.9 12.7 10.5 14.3 13.0 22.0 10.8 6.0 6.6 5.8 17.4 12.8 10.2 9.5 5.2 5.5 13.4 10.6 17.6 5.7 11.9 4.7 13.3 14.5 11.4 12.5 10.2 5.0 14.3 12.8 9.5 4.6 8.3 11.1 8.3 5.6 11.0 16.5 5.3 9.2 11.8 7.6 10.0 22.3 13.4 21.5 13.1 17.0 20.3 38.5 19.6 14.6 18.2 17.1 18.3 41.3 24.0 21.8 12.7 22.5 27.0 17.0 25.5 20.2 33.3 19.2 29.0 12.4 19.5 19.1 12.7 15.7 14.1 38.1 18.4 43.2 26.0 16.3 24.9 29.2 23.6 26.3 11.8 31.8 17.0 24.1 46.1 6.5 22.6 8.9 15.7 29.9 16.9 18.0 16.2 12.6 20.3 39.9 27.7 30.2 16.0 13.2 13.8 17.6 23.6 16.2 20.1 27.4 31.4 18.7 20.6 21.1 35.0 7.6 5.9 7.8 5.0 11.1 10.0 9.1 8.1 8.3 9.7 7.5 10.9 8.4 9.4 9.3 7.6 7.4 4.4 5.8 6.5 13.2 8.4 6.6 5.8 5.2 5.5 4.7 4.6 5.6 10.0 10.5 12.8 12.7 10.7 13.4 34.2 28.0 38.4 19.9 18.2 14.2 12.1 5.2 15.7 30.4 25.8 14.6 32.9 14.6 15.3 13.7 16.4 2.3 42.0 10.4 11.1 15.0 20.0 17.0 8.0 21.1 12.2 13.3 10.4 5.7 12.6 11.4 12.5 13.2 21.9 21.6 26.5 40.7 12.6 11.0 1.2 13.1 9.0 7.2 20.6 13.0 17.2 9.2 26.7 16.9 15.8 21.6 13.9 14.6 26.9 17.4 22.0 66.7 15.3 26.3 9.2 10.8 16.2 15.3 17.5 35.5 22.2 11.7 15.3 15.8 29.3 TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" 18.1 18.2 9.2 9.8 9.7 10.4 11.3 10.5 12.3 8.0 9.5 12.6 5.8 8.9 10.6 9.3 11.3 8.9 19.3 10.3 10.2 12.0 24.4 9.0 10.1 9.6 9.1 10.5 25.0 8.3 7.6 10.3 10.1 7.4 9.7 6.1 9.9 5.9 100.7 7.7 9.5 9.1 9.5 9.6 17.8 9.8 9.5 11.0 6.0 20.5 10.3 11.3 7.4 10.1 21.2 16.4 13.1 13.8 14.9 12.7 13.6 17.6 15.8 19.4 15.3 15.8 11.9 28.4 15.0 12.0 16.4 19.1 24.9 16.8 21.4 18.9 17.5 28.3 10.0 21.2 14.7 15.5 14.5 11.8 15.3 12.2 6.4 7.3 16.4 14.2 22.0 13.5 20.5 15.9 35.8 29.6 12.3 26.6 20.6 25.4 12.8 24.2 20.5 20.0 29.7 13.1 11.0 78.0 23.3 10.2 16.0 14.1 10.6 11.1 13.7 20.7 16.9 19.9 18.7 28.1 16.4 12.1 12.5 6.3 9.1 6.7 8.0 10.2 9.1 17.7 9.0 9.3 9.6 10.9 10.3 9.6 6.7 5.8 7.9 11.0 7.9 12.0 9.2 9.7 10.5 12.3 10.3 10.2 9.6 9.1 10.1 9.5 9.5 10.1 136.2 16.0 30.1 5.5 37.1 67.3 43.7 54.8 24.5 23.9 26.2 22.2 46.3 14.3 35.7 22.0 8.4 71.2 48.1 69.0 66.5 36.6 20.3 40.8 26.2 96.4 13.8 26.5 12.8 63.5 59.6 50.2 17.3 17.1 39.9 17.0 28.5 50.3 132.4 10.1 11.4 31.7 42.7 70.0 74.5 12.1 29.8 73.2 40.9 5.6 38.9 23.1 22.6 3.5 8.1 43.6 37.9 29.0 68.6 42.1 28.8 75.4 58.7 17.5 39.5 61.9 40.8 70.6 29.5 21.5 59.7 70.3 39.8 52.6 34.1 26.2 TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "dendritic cells: 39.9;Kupffer cells: 20.7;Langerhans cells: 25.7;Macrophages: 26.2;monocytes: 25.5;NK-cells: 54.6;T-cells: 35.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HDLM-2: 54.5;Karpas-707: 11.1;U-937: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" 5.6 2.0 1.0 13.1 1.3 33.5 8.5 1.0 9.7 2.5 2.2 11.3 2.2 1.3 1.1 2.8 1.9 5.5 37.1 1.1 1.8 2.6 3.9 8.2 13.2 1.6 1.3 1.0 2.4 0.7 1.1 1.8 2.1 2.0 3.4 0.5 5.7 2.2 1.6 1.1 7.3 3.6 1.1 18.4 2.8 1.0 2.4 19.2 2.0 4.6 10.6 4.6 1.9 1.6 0.4 0.0 4.9 0.0 0.0 0.0 0.0 1.3 12.7 0.5 0.9 0.0 0.0 0.1 0.6 4.1 0.1 0.0 0.0 0.3 1.5 54.5 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.1 0.0 0.1 2.0 1.4 1.0 6.7 0.0 11.1 2.4 0.0 2.9 2.2 1.2 0.0 0.4 0.1 1.8 0.8 4.8 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 2.1 0.5 0.9 1.2 5.7 0.1 2.9 0.0 9.0 31.6 3.7 61.9 55.9 101.6 31.3 16.1 57.9 6.6 22.8 22.2 33.7 4.7 33.9 25.1 269.0 12.9 14.7 1.1 3.0 39.0 1.0 1.3 1.0 9.7 1.1 1.8 1.6 1.3 2.1 1.1 2.4 1.6 0.5 0.0 3.0 0.0 6.9 0.9 1.0 2.5 0.6 0.0 4.2 2.7 15.9 0.0 5.5 0.0 0.0 0.0 39.9 0.1 0.0 0.0 6.5 0.1 0.3 1.5 0.0 8.8 0.5 0.0 0.0 4.1 1.1 0.2 1.3 0.0 3.3 0.2 3.2 0.0 1.3 0.2 0.0 20.7 25.7 5.1 0.0 26.2 5.4 17.8 25.5 1.9 54.6 0.0 0.1 0.1 0.0 0.0 11.3 0.1 0.0 0.4 2.9 0.0 0.0 3.7 0.8 0.0 0.6 0.4 0.3 0.3 35.9 0.1 0.0 4.5 TMEM74 "FLJ30668, NET36" ENSG00000164841 "Transmembrane protein 74" Q96NL1 8 108606850-108787594 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 4.6;Bipolar cells: 4.7;Cone photoreceptor cells: 6.2;Excitatory neurons: 5.1;Muller glia cells: 3.3;Rod photoreceptor cells: 8.3;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.7;JURKAT: 1.5;NTERA-2: 2.1;RH-30: 1.5;SCLC-21H: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015672, HPA076461" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Cytosol" "HPA015672: AB_1858132, HPA076461: " "unprognostic (8.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.25e-2)" "unprognostic (6.33e-2)" "unprognostic (2.05e-1)" "unprognostic (4.18e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-2)" "unprognostic (3.97e-2)" "unprognostic (3.75e-4)" "unprognostic (8.77e-2)" "unprognostic (6.36e-2)" "unprognostic (5.95e-2)" "unprognostic (1.46e-3)" 0.3 0.2 1.8 0.1 2.2 0.0 0.2 4.7 2.4 0.2 1.4 1.3 0.0 0.1 0.0 0.5 0.1 0.1 1.3 3.7 3.0 0.1 0.8 0.1 0.0 3.8 1.7 0.1 0.5 0.0 0.4 0.0 3.5 0.1 0.1 2.5 0.2 0.1 0.8 0.3 0.2 0.4 6.1 0.1 0.3 0.3 1.6 0.3 0.1 0.2 0.1 0.2 0.4 8.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 1.7 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 1.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.2 4.7 2.4 3.7 3.0 3.8 1.7 3.5 6.1 1.6 8.2 0.4 0.0 0.0 2.0 0.0 0.9 0.7 0.0 4.6 4.7 0.2 0.6 0.8 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.3 1.8 0.0 5.1 0.2 0.8 0.7 0.0 0.1 0.0 0.5 0.0 0.7 0.1 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 8.3 0.0 0.8 0.9 0.2 4.1 2.0 0.6 0.1 0.1 0.1 0.0 0.0 TMEM74B "C20orf46, FLJ11190" ENSG00000125895 "Transmembrane protein 74B" Q9NUR3 20 1180561-1185415 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 15.6;Horizontal cells: 18.5;Inhibitory neurons: 16.3;Paneth cells: 15.6;Proximal enterocytes: 21.1;Sertoli cells: 19.7;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.3;Hep G2: 9.2;K-562: 16.8;Karpas-707: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045213 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Golgi apparatus" "HPA045213: AB_10961999" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (5.73e-2)" "unprognostic (1.03e-2)" "unprognostic (6.91e-3)" "unprognostic (1.97e-1)" "unprognostic (1.77e-4)" "unprognostic (9.58e-2)" "prognostic favorable (3.07e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.55e-7)" "unprognostic (1.20e-1)" "unprognostic (9.77e-2)" "unprognostic (8.37e-2)" "unprognostic (5.07e-3)" 5.8 2.0 17.5 1.0 16.2 0.2 4.9 10.3 19.4 1.9 8.8 4.0 18.2 2.0 0.8 4.0 7.4 3.9 11.2 13.5 16.6 4.5 4.7 27.6 2.0 19.8 13.2 1.0 2.0 7.1 10.1 17.2 18.2 3.1 1.8 3.9 6.3 15.7 5.1 9.8 23.1 2.0 10.8 2.8 4.1 4.1 17.8 0.3 4.1 2.2 1.2 1.2 2.0 11.5 0.0 4.4 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.3 0.6 0.1 0.9 0.0 2.7 0.3 3.4 0.4 0.1 0.0 4.2 1.1 0.0 9.2 0.0 0.0 1.2 0.0 0.9 0.0 0.1 0.1 0.1 0.6 16.8 7.1 0.0 0.0 0.1 0.0 3.0 1.2 0.3 0.0 0.2 0.0 0.7 0.6 0.5 1.9 0.1 0.0 0.1 0.9 0.0 0.0 1.7 0.0 2.9 0.0 0.1 2.7 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 16.2 10.3 19.4 13.5 16.6 19.8 13.2 18.2 10.8 17.8 11.5 3.7 0.0 0.0 0.7 0.1 0.3 0.7 0.9 0.6 10.5 2.2 1.0 2.3 0.0 0.2 0.0 0.0 0.2 0.2 1.0 0.0 0.5 1.0 0.2 0.1 3.3 15.6 0.0 9.7 0.2 1.8 0.8 2.6 0.1 0.0 0.5 4.6 0.8 0.0 18.5 16.3 9.9 2.0 0.6 0.7 0.7 0.0 1.4 1.8 1.9 1.0 0.5 0.0 0.0 1.1 0.9 15.6 0.0 0.1 0.7 21.1 0.6 1.2 4.0 19.7 0.4 13.3 0.2 2.7 0.2 0.9 1.4 0.2 0.3 3.9 0.3 TMEM80 FLJ38216 ENSG00000177042 "Transmembrane protein 80" Q96HE8 11 695428-705028 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 82.2;Spermatogonia: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059592, HPA067046" Uncertain Approved "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus" "HPA059592: AB_2684076, HPA067046: AB_2685769" "unprognostic (1.48e-1)" "unprognostic (6.55e-3)" "unprognostic (1.70e-2)" "unprognostic (2.64e-2)" "unprognostic (2.71e-3)" "unprognostic (1.68e-3)" "unprognostic (4.36e-2)" "unprognostic (5.39e-3)" "unprognostic (3.85e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-3)" "unprognostic (1.03e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (3.27e-1)" "unprognostic (4.23e-3)" 21.0 23.0 18.4 14.7 18.2 6.5 23.8 19.5 22.0 30.5 17.3 30.2 23.7 27.8 24.8 42.5 30.1 8.4 15.3 19.3 16.5 36.0 20.2 17.5 21.2 21.2 18.1 29.7 29.7 17.8 34.3 8.7 19.0 29.9 17.5 9.1 31.5 19.4 19.7 31.0 31.1 12.7 18.9 34.3 30.8 24.8 19.0 19.7 47.6 11.8 21.3 27.8 30.6 19.9 37.8 17.5 11.0 14.3 23.6 11.1 19.0 8.5 4.7 8.9 9.6 23.9 42.0 16.0 7.3 13.2 15.8 26.8 16.2 9.7 6.3 11.0 41.7 9.7 19.0 14.5 13.9 12.8 16.8 25.7 19.9 4.0 6.2 17.5 10.5 18.9 12.1 17.7 11.4 12.2 16.8 8.7 10.4 29.9 8.4 12.2 7.6 31.5 12.7 5.7 31.1 9.8 12.8 23.5 12.3 7.3 18.2 11.9 15.0 14.9 7.8 3.4 6.4 8.4 3.2 14.8 15.6 15.9 6.5 8.3 26.5 35.4 21.0 25.9 18.4 26.7 15.7 16.0 21.8 30.1 22.3 20.0 12.8 21.4 32.0 22.0 21.4 20.7 18.4 18.2 19.5 22.0 19.3 16.5 21.2 18.1 19.0 18.9 19.0 19.9 15.1 6.4 20.7 13.7 24.0 15.3 15.9 25.6 17.6 22.7 31.7 36.8 19.3 15.7 20.2 20.2 8.4 33.9 19.4 15.4 11.7 13.0 9.2 17.1 15.8 14.4 12.1 8.6 13.9 17.1 9.8 20.8 9.7 19.9 7.0 15.9 12.8 6.2 17.6 55.5 13.1 22.7 28.5 13.2 13.6 9.5 42.6 12.7 12.4 11.2 19.7 23.2 26.8 16.6 16.7 10.6 10.3 28.6 11.5 12.3 22.1 8.1 19.4 9.1 32.9 23.4 21.2 82.2 87.2 13.7 17.2 15.2 16.7 21.6 19.5 12.3 TMEM87A DKFZP564G2022 ENSG00000103978 "Transmembrane protein 87A" Q8NBN3 15 42210447-42273584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 264.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018104, HPA018189" Enhanced Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" "HPA018104: AB_1858135, HPA018189: AB_2205198" "unprognostic (7.07e-2)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (2.49e-1)" "unprognostic (6.39e-3)" "unprognostic (1.19e-2)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (8.13e-3)" "unprognostic (4.31e-3)" "unprognostic (1.38e-1)" "unprognostic (3.41e-2)" "unprognostic (7.90e-2)" "unprognostic (2.19e-1)" "unprognostic (5.49e-3)" "unprognostic (3.63e-1)" 31.8 26.3 23.7 26.1 37.7 88.2 97.7 32.0 29.5 40.2 17.7 56.5 26.6 38.6 49.3 48.2 45.3 32.4 19.7 23.5 26.3 27.1 24.5 72.8 25.4 36.7 29.4 35.4 34.9 47.9 14.2 42.7 38.7 79.8 60.9 26.1 64.7 36.6 24.9 50.2 26.9 38.0 32.5 23.1 38.6 33.0 28.8 24.8 75.9 22.2 30.9 42.0 34.3 59.1 41.0 20.5 30.5 27.0 58.5 50.3 47.7 55.1 82.0 53.5 52.0 29.8 87.5 17.4 52.9 59.9 60.5 104.0 28.3 51.2 42.8 46.8 25.0 35.6 51.5 33.5 63.4 65.6 48.3 52.3 112.1 39.5 65.3 50.6 41.9 30.1 39.4 67.4 51.7 26.3 21.3 38.8 25.7 60.8 29.3 33.5 46.6 36.8 34.5 127.4 33.7 41.2 53.1 70.1 49.9 24.0 27.4 62.4 41.3 104.4 25.5 68.1 82.6 46.8 95.0 36.5 40.1 47.9 66.8 58.3 26.9 31.2 29.0 32.3 33.3 27.6 35.6 34.0 24.4 24.4 33.6 33.5 15.2 42.4 34.7 22.4 42.2 26.0 23.7 37.7 32.0 29.5 23.5 26.3 36.7 29.4 38.7 32.5 28.8 59.1 66.2 125.0 264.0 46.0 48.9 68.6 90.2 78.8 58.1 31.2 148.7 105.9 13.9 45.8 98.0 49.7 50.1 78.1 57.5 77.7 1.9 63.7 5.6 57.0 67.0 54.6 32.2 34.5 41.7 64.2 72.7 64.0 50.0 124.7 59.5 42.9 51.0 34.4 41.6 20.2 48.2 74.1 67.1 39.2 37.0 7.9 41.0 41.3 62.2 45.0 60.1 61.8 52.5 74.4 177.5 56.1 62.4 53.8 47.6 118.5 36.6 15.5 86.4 63.0 85.5 77.0 59.0 59.4 61.4 79.1 65.5 110.4 54.8 53.3 76.9 105.6 TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" 10.5 12.2 6.8 14.7 6.6 7.9 20.1 6.1 8.0 12.9 6.9 28.4 28.6 11.0 18.5 10.5 8.4 12.1 5.0 5.9 7.1 7.9 7.4 11.7 15.4 7.5 10.0 6.0 11.3 12.9 9.2 15.1 8.0 30.7 27.8 6.9 15.4 15.9 3.1 13.7 30.5 13.4 7.1 15.5 22.8 5.0 8.3 9.7 15.0 4.2 14.6 17.1 9.0 6.9 21.7 6.4 5.9 25.8 24.9 32.6 21.4 35.5 46.8 21.9 26.7 16.6 28.6 20.9 18.2 47.3 30.2 34.9 3.8 21.6 28.7 12.8 4.1 27.5 4.6 15.2 24.7 19.6 28.9 22.3 25.9 28.0 22.0 21.4 23.6 9.6 16.9 13.1 31.8 13.7 9.3 10.8 4.8 35.0 16.4 7.6 8.9 17.0 20.3 30.2 4.6 6.4 15.4 38.6 34.6 15.5 20.4 14.7 26.6 22.3 6.8 17.6 7.8 10.6 18.1 12.9 25.9 10.1 16.3 5.4 3.0 2.6 3.2 5.2 5.6 5.9 6.9 4.4 2.7 4.9 6.2 3.6 1.8 3.5 6.7 2.7 7.4 3.6 6.8 6.6 6.1 8.0 5.9 7.1 7.5 10.0 8.0 7.1 8.3 6.9 18.3 28.9 13.9 18.9 23.3 12.2 14.5 20.9 39.9 5.0 32.9 14.4 4.6 20.0 21.6 18.4 2.1 15.9 12.3 59.5 0.0 42.9 18.7 14.4 26.5 19.9 17.4 6.3 18.4 89.3 25.5 17.5 46.4 24.9 13.3 14.5 35.7 10.1 21.7 6.7 16.4 53.6 12.2 37.7 10.9 24.5 9.9 22.7 3.6 30.0 20.9 4.0 6.2 21.6 23.1 69.7 47.1 3.0 21.6 28.9 44.9 4.7 17.9 7.9 0.0 5.4 17.2 4.9 5.6 29.9 12.8 29.1 20.5 11.8 38.2 23.9 TMEM88 "FLJ20025, MGC71744" ENSG00000167874 "Transmembrane protein 88" Q6PEY1 17 7855066-7856099 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.5" "Group enriched" "Detected in many" 7 "Adipocytes: 177.3;Endothelial cells: 142.1;Hepatic stellate cells: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Group enriched" "Detected in many" 6 "AN3-CA: 65.2;HHSteC: 42.3;HUVEC TERT2: 51.4;NTERA-2: 26.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052991 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052991: AB_2682006" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (3.44e-2)" "unprognostic (3.03e-1)" "unprognostic (6.49e-2)" "prognostic favorable (4.43e-6)" "unprognostic (1.98e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-1)" "unprognostic (5.68e-3)" "unprognostic (9.04e-2)" "unprognostic (1.09e-2)" "unprognostic (2.68e-3)" "unprognostic (1.71e-1)" "unprognostic (7.56e-2)" "unprognostic (2.72e-1)" 63.2 22.3 11.2 7.9 11.0 6.9 29.5 12.4 24.4 20.0 14.3 18.1 5.7 24.1 3.6 6.4 26.4 12.7 98.5 11.3 11.6 37.7 5.9 14.1 3.6 12.6 11.6 8.5 10.8 7.4 21.4 23.7 12.0 19.3 2.7 2.4 9.3 6.3 35.4 3.8 15.4 10.1 11.0 15.9 18.2 4.9 12.9 2.5 39.6 36.8 0.8 19.1 14.0 10.9 0.2 0.8 8.1 65.2 0.0 0.3 3.9 0.4 0.2 0.1 0.2 1.9 0.3 0.4 0.3 0.7 0.4 0.5 0.6 0.4 0.1 0.0 0.1 0.5 1.2 1.1 42.3 0.6 2.6 1.0 1.8 1.2 0.3 0.6 51.4 0.9 1.2 0.1 0.8 5.0 0.5 1.2 26.5 0.3 0.0 0.3 0.2 0.1 0.6 1.6 0.7 3.7 0.5 0.8 2.0 2.2 1.4 0.2 5.2 0.4 1.6 2.2 0.5 0.2 0.1 0.4 0.2 0.4 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 11.2 11.0 12.4 24.4 11.3 11.6 12.6 11.6 12.0 11.0 12.9 10.9 177.3 6.4 2.2 2.0 6.2 4.1 4.0 1.4 2.2 4.7 7.9 5.2 5.9 0.0 2.4 1.8 4.2 3.1 3.1 2.0 0.0 2.2 3.0 3.1 2.0 142.1 6.6 0.0 0.6 2.2 1.0 19.2 4.6 6.7 4.5 1.8 109.9 2.4 2.6 3.3 0.9 2.5 0.0 7.3 9.3 8.6 0.9 9.9 0.0 5.6 0.2 0.6 0.0 0.0 0.1 4.0 5.7 0.0 1.0 6.5 2.4 0.6 1.5 1.4 0.0 11.3 6.5 1.7 1.8 2.7 3.1 5.2 2.5 0.8 1.5 3.2 TMEM88B ENSG00000205116 "Transmembrane protein 88B" A6NKF7 1 1426128-1427787 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 196 "brain: 437.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 4.2;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065743 Enhanced NA NA "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "HPA065743: AB_2685552" "unprognostic (3.17e-2)" "unprognostic (1.42e-2)" "unprognostic (1.63e-4)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "unprognostic (2.67e-1)" "unprognostic (2.91e-2)" "unprognostic (5.30e-5)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (3.53e-2)" "unprognostic (7.19e-2)" "unprognostic (1.45e-1)" "unprognostic (7.95e-2)" 0.0 0.0 95.5 0.1 285.1 0.0 0.0 192.8 193.1 0.2 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 82.8 125.8 1.0 0.0 0.1 0.0 312.3 232.8 0.1 0.0 0.0 0.0 0.0 199.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 129.9 0.0 0.0 2.2 242.8 0.0 0.0 0.0 0.0 0.3 0.1 437.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 285.1 192.8 193.1 82.8 125.8 312.3 232.8 199.0 129.9 242.8 437.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 36.1;Granulosa cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.2" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA052130: AB_2681740, HPA062701: AB_2684839" "unprognostic (5.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.96e-1)" "unprognostic (3.53e-2)" "unprognostic (3.81e-1)" "unprognostic (1.42e-1)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (2.97e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.14e-4)" "unprognostic (5.93e-2)" "prognostic favorable (1.89e-15)" "unprognostic (8.00e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" 10.4 21.1 19.9 3.1 16.0 1.8 12.3 11.5 20.7 21.7 3.6 19.9 5.1 20.1 6.2 5.7 20.8 6.7 15.9 20.3 13.9 15.8 6.4 10.2 3.6 14.2 15.3 33.6 11.8 17.8 30.6 4.5 13.9 23.9 5.5 7.7 18.1 14.2 12.8 9.3 9.5 6.9 12.7 8.5 17.7 19.1 18.5 5.2 22.7 9.6 2.6 19.3 15.7 12.4 3.1 3.4 11.7 9.2 12.9 10.7 1.4 2.8 5.5 3.1 3.8 1.4 0.8 2.5 6.5 7.7 9.1 1.2 3.1 4.7 2.5 1.9 5.2 0.7 2.5 3.4 9.1 0.2 0.2 10.1 6.1 3.2 3.4 10.0 1.8 11.5 1.2 6.9 5.5 1.2 6.6 1.4 1.6 2.7 4.6 7.2 2.4 6.2 3.3 1.5 2.8 8.1 4.3 1.8 4.1 3.8 3.2 1.1 2.9 7.3 2.2 7.2 1.1 8.6 2.8 2.8 6.7 1.2 4.6 0.7 2.1 0.2 0.5 0.1 0.3 0.6 0.4 0.4 8.2 0.5 0.4 0.4 0.9 0.7 0.1 51.2 0.2 1.3 19.9 16.0 11.5 20.7 20.3 13.9 14.2 15.3 13.9 12.7 18.5 12.4 4.4 12.8 12.2 18.9 3.3 4.5 9.1 8.1 8.0 4.1 12.1 11.4 11.7 10.0 9.1 14.7 2.1 34.1 36.1 8.2 1.9 5.7 25.4 7.7 8.4 3.2 6.7 0.8 12.4 4.0 9.2 9.2 11.2 6.3 1.3 47.3 1.8 4.0 3.2 1.7 13.0 7.0 12.2 1.3 11.2 14.0 14.6 5.3 10.6 10.3 3.6 9.1 2.1 12.1 7.2 3.6 8.0 19.5 2.6 9.0 3.0 4.5 7.5 5.3 6.6 7.1 8.7 8.6 5.2 1.9 1.6 13.0 3.6 8.1 7.8 10.0 TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.0;Late spermatids: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 193.3" "Group enriched" "Detected in all" 8 "granulocytes: 193.3;monocytes: 51.9" "Cell line enhanced" "Detected in many" "HEL: 20.1;HSkMC: 20.5;TIME: 19.8" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA053240: AB_2682085" "unprognostic (3.02e-3)" "unprognostic (1.92e-2)" "unprognostic (5.13e-3)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.69e-3)" "prognostic favorable (3.54e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.06e-2)" 24.0 12.8 32.3 6.9 43.1 36.2 19.7 19.5 35.2 39.1 27.7 26.6 3.5 18.6 10.2 22.6 30.2 8.2 16.4 29.3 49.0 20.3 9.6 23.3 6.5 29.2 33.3 20.1 17.7 4.1 26.2 9.4 28.4 23.0 3.9 9.2 11.4 8.6 5.4 66.3 14.3 8.7 23.3 37.5 12.3 37.8 52.7 5.7 20.5 7.3 7.6 29.8 31.3 24.2 3.3 7.0 5.4 2.7 6.4 13.6 5.0 2.6 3.4 1.3 2.1 0.5 2.9 1.5 2.4 3.0 2.1 0.9 1.3 2.4 3.0 2.3 3.6 20.1 5.7 11.1 12.3 3.4 5.2 20.5 12.6 4.0 9.8 14.8 9.2 3.7 3.8 6.2 2.1 6.3 2.5 6.6 2.3 0.9 4.2 4.2 1.2 1.4 3.4 1.6 1.4 3.3 5.0 1.0 4.1 3.8 1.3 9.9 19.8 3.1 3.0 2.9 2.7 3.8 0.6 1.1 6.5 4.6 1.2 36.8 51.9 4.0 5.9 12.3 7.4 0.7 3.4 3.1 9.5 1.4 8.0 3.9 193.3 1.5 9.1 14.6 4.7 41.2 32.3 43.1 19.5 35.2 29.3 49.0 29.2 33.3 28.4 23.3 52.7 24.2 20.2 3.2 22.4 23.8 3.5 17.8 22.9 59.8 7.4 8.3 10.7 15.9 5.3 2.8 25.0 7.3 6.2 2.7 10.6 0.7 1.9 5.3 212.0 12.0 12.1 13.7 14.4 4.8 11.7 3.2 84.3 21.7 1.1 4.8 34.2 13.0 20.0 3.8 15.7 8.4 18.9 1.6 10.2 67.6 8.4 451.5 14.0 51.6 8.8 7.5 30.7 4.1 20.6 5.0 5.8 3.8 18.5 7.2 1.7 6.5 2.3 2.5 13.5 6.4 6.6 4.8 8.6 4.9 9.0 9.7 21.3 8.6 7.8 3.7 1.7 10.4 TMEM94 KIAA0195 ENSG00000177728 "Transmembrane protein 94" Q12767 17 75441159-75500452 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.0;Granulosa cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008423, HPA050660" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA008423: AB_1852283, HPA050660: AB_2681207" "unprognostic (4.05e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (7.27e-2)" "prognostic favorable (2.26e-4)" "unprognostic (9.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.44e-2)" "unprognostic (4.96e-2)" 21.3 55.9 50.3 13.9 46.4 18.4 21.7 27.7 54.9 21.9 30.5 25.1 18.8 24.4 5.4 21.1 30.7 15.8 27.8 40.7 31.5 29.7 20.2 25.6 14.1 40.1 36.8 27.7 23.7 20.3 30.1 14.2 30.5 19.9 13.6 27.7 21.1 13.2 63.4 22.9 28.2 10.7 34.8 29.7 25.0 27.1 47.1 18.0 27.4 25.8 8.6 20.5 15.3 35.8 15.3 40.7 33.6 52.6 16.1 18.8 45.6 9.2 20.0 15.4 15.4 13.7 22.6 20.6 30.3 15.9 23.6 19.9 15.8 25.6 8.8 19.4 23.1 22.0 18.4 22.9 21.2 23.7 45.2 30.9 14.5 15.0 13.4 13.9 28.1 18.3 22.6 24.4 20.7 19.1 53.3 18.8 14.4 19.3 16.2 36.2 37.2 19.2 16.0 40.7 28.1 30.5 10.2 47.4 28.7 25.3 29.8 29.3 16.0 16.5 19.0 16.5 13.8 53.2 17.2 12.2 17.2 23.8 20.8 0.1 2.6 3.0 3.5 1.6 2.6 1.0 1.6 2.5 2.5 2.5 1.3 2.2 0.7 2.4 1.4 3.3 2.1 2.9 50.3 46.4 27.7 54.9 40.7 31.5 40.1 36.8 30.5 34.8 47.1 35.8 12.8 12.8 11.1 0.0 5.8 0.0 3.3 0.0 6.2 43.0 10.9 9.1 0.0 12.8 6.2 9.2 31.3 16.1 8.8 18.0 0.0 8.1 4.7 10.1 6.8 8.2 7.3 10.7 0.0 9.5 11.0 4.4 28.1 8.6 6.3 41.5 13.9 8.9 15.4 20.2 0.0 10.5 0.0 12.4 0.0 1.9 6.8 8.9 0.0 0.0 5.6 15.2 4.1 0.0 0.0 6.0 9.1 9.1 8.1 3.3 19.6 3.4 2.9 33.6 6.6 7.5 6.0 14.9 8.8 9.7 0.0 20.1 6.9 19.0 9.3 3.1 TMEM97 MAC30 ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.4;pancreas: 322.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 121.5;Exocrine glandular cells: 196.4;Granulosa cells: 212.9;Hepatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 341.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" 4.3 26.0 5.2 7.3 6.3 6.7 11.7 6.6 9.0 5.7 6.5 14.3 16.4 6.7 4.7 7.4 13.1 10.2 3.4 6.3 5.4 7.1 113.4 17.4 7.1 14.9 14.2 18.1 322.0 6.5 1.6 6.8 14.9 10.8 12.6 6.3 3.7 3.3 15.5 9.8 11.2 5.7 5.0 4.6 38.8 58.0 7.4 7.6 4.2 9.1 8.2 26.6 5.2 6.8 46.1 120.4 214.8 105.5 28.0 40.2 70.5 44.1 27.9 67.9 90.3 341.0 34.3 126.3 46.4 17.0 140.1 48.7 137.1 75.0 52.7 60.3 102.1 47.8 56.9 143.0 25.7 76.9 36.4 84.0 10.0 66.4 27.5 8.3 21.1 80.1 101.3 92.1 22.7 81.8 120.0 72.4 95.6 187.7 30.6 94.8 236.5 112.8 85.6 210.6 154.1 67.0 70.0 55.1 36.3 118.2 97.0 35.8 13.8 72.8 56.8 62.9 81.7 74.3 159.0 115.9 14.6 54.7 44.3 0.7 2.2 2.2 7.8 2.7 9.2 11.1 6.4 9.4 16.1 5.5 10.4 9.8 1.0 9.5 1.0 9.3 6.6 5.2 5.2 6.3 6.6 9.0 6.3 5.4 14.9 14.2 14.9 5.0 7.4 6.8 4.2 9.6 61.5 3.3 7.7 14.5 6.0 32.8 18.8 11.3 22.5 21.5 9.0 121.5 19.1 14.7 16.7 34.2 5.0 6.1 15.6 23.3 22.3 7.5 14.3 7.1 38.8 40.3 2.9 196.4 84.0 14.4 49.5 11.4 1.3 212.9 6.4 226.9 22.0 3.3 4.5 16.2 26.4 6.7 34.7 49.1 13.4 9.9 16.0 0.0 11.4 8.2 4.1 4.0 1.0 47.7 3.5 11.3 15.3 13.9 4.0 6.3 12.2 9.1 6.6 10.4 12.4 91.3 65.5 22.7 11.2 10.7 6.4 65.1 29.4 7.9 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Astrocytes: 64.6;Excitatory neurons: 186.0;Inhibitory neurons: 200.5;Skeletal myocytes: 60.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 83.0;HSkMC: 56.9;hTERT-HME1: 103.8;LHCN-M2: 58.8;RH-30: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" 36.7 14.1 14.5 5.2 21.0 0.2 16.8 6.7 13.5 11.9 13.3 11.9 3.1 9.0 3.0 6.8 14.3 7.1 16.5 20.0 25.0 14.7 2.4 8.7 2.7 11.4 24.0 9.3 2.6 28.0 10.7 2.8 15.8 6.9 5.9 2.6 4.5 8.8 18.5 4.0 6.4 13.2 7.9 42.4 8.3 2.4 25.1 6.9 4.7 31.2 2.1 12.1 8.2 6.3 0.0 0.0 15.3 0.0 47.7 31.6 0.1 14.7 33.1 4.3 3.4 0.0 0.2 0.1 7.4 10.0 17.6 0.0 0.5 0.2 0.2 0.3 4.6 0.0 41.5 0.7 83.0 2.1 0.0 56.9 5.6 40.3 103.8 12.2 2.2 0.0 0.0 2.2 58.8 0.0 0.0 0.0 11.1 0.2 20.8 0.0 122.4 2.1 0.0 0.3 1.2 1.2 1.7 0.0 4.1 5.4 0.0 0.8 6.2 3.7 2.4 2.3 12.5 19.6 0.0 0.0 27.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.5 21.0 6.7 13.5 20.0 25.0 11.4 24.0 15.8 7.9 25.1 6.3 105.0 3.2 0.6 64.6 0.9 3.3 1.0 6.1 11.4 12.1 1.3 10.4 32.3 0.0 2.4 3.7 0.0 0.1 0.0 0.0 0.0 0.1 29.6 7.7 16.2 57.9 0.0 0.0 186.0 0.0 0.0 17.5 2.0 7.0 0.0 4.3 54.7 5.4 0.5 0.0 200.5 0.2 0.0 17.7 4.2 7.5 8.1 4.9 10.6 30.9 0.5 0.5 0.0 9.5 5.7 0.0 0.0 18.4 0.3 4.0 0.1 0.7 6.0 1.3 46.0 60.3 24.9 2.4 1.7 1.3 2.0 1.9 1.0 21.9 0.0 0.4 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 191.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" 33.1 53.3 26.8 25.6 24.7 23.0 34.3 25.6 38.6 34.0 19.4 52.7 47.2 33.6 8.6 54.2 32.8 14.9 50.4 24.9 24.6 56.3 131.3 41.6 26.3 29.6 25.9 37.0 93.5 20.3 68.8 20.4 27.0 51.2 8.3 5.2 44.1 14.9 84.5 47.0 56.7 9.0 24.2 53.6 66.8 25.9 29.4 17.9 51.3 20.0 12.1 40.8 38.9 23.7 88.3 77.5 18.0 93.2 11.6 14.2 67.2 35.3 29.3 30.8 34.3 67.5 104.6 58.6 73.9 17.4 39.9 58.6 20.0 31.2 6.8 108.0 74.4 24.8 74.8 104.7 29.5 31.3 84.8 22.0 25.4 25.8 6.9 23.4 22.9 59.3 159.4 77.4 14.0 141.2 104.5 134.5 77.2 51.7 48.3 64.8 22.7 108.5 32.2 67.4 65.6 73.2 28.6 43.6 47.9 10.6 34.0 42.9 28.3 39.0 28.5 49.3 59.1 121.2 72.5 41.4 89.8 58.2 50.4 4.2 3.1 23.8 5.7 4.3 5.0 5.3 8.7 6.4 3.2 11.2 8.7 4.8 5.3 3.7 2.6 4.8 12.1 2.4 26.8 24.7 25.6 38.6 24.9 24.6 29.6 25.9 27.0 24.2 29.4 23.7 24.0 6.4 3.2 7.5 51.2 26.4 25.9 26.0 31.9 15.2 45.7 34.8 9.9 28.6 15.9 22.0 14.6 93.1 50.2 136.7 35.2 73.1 11.9 15.8 11.7 21.5 41.3 23.2 4.5 109.6 60.2 18.3 52.0 29.3 15.9 23.3 25.4 51.4 44.2 20.2 5.3 85.9 46.8 30.4 61.2 5.1 12.5 32.4 32.0 6.5 44.8 28.9 70.0 2.5 7.2 96.3 109.7 16.6 67.8 39.3 191.0 37.9 6.4 16.0 39.5 9.3 21.8 22.3 15.6 39.5 36.9 94.5 52.8 25.4 84.0 37.9 TMUB2 MGC3123 ENSG00000168591 "Transmembrane and ubiquitin like domain containing 2" Q71RG4 17 44186970-44191929 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043137 Approved Approved Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Vesicles, Cytosol" "HPA043137: AB_10794388" "unprognostic (4.57e-2)" "unprognostic (1.58e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-2)" "unprognostic (6.37e-2)" "unprognostic (1.85e-2)" "unprognostic (6.43e-3)" "unprognostic (1.07e-1)" "unprognostic (2.05e-1)" "unprognostic (3.35e-2)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "unprognostic (2.78e-3)" 32.2 35.7 34.1 22.9 34.4 43.9 32.5 34.9 38.1 37.3 32.5 39.1 24.5 32.5 21.9 37.3 33.9 25.2 33.1 34.2 32.8 36.9 35.8 31.5 26.3 33.6 33.8 35.2 36.9 27.5 32.9 25.9 32.9 42.0 21.9 16.8 36.1 26.3 32.7 32.4 36.5 21.7 32.2 52.8 36.7 46.8 34.2 23.2 42.7 20.0 20.5 35.3 34.3 34.3 22.8 43.0 27.6 25.1 41.6 32.8 21.6 29.5 31.6 53.7 54.4 22.7 41.5 15.8 31.1 36.1 40.5 42.3 19.3 28.0 33.4 38.7 39.7 16.5 40.9 35.1 43.8 18.7 35.5 40.1 39.8 36.9 22.9 45.1 37.8 25.8 19.2 45.4 35.7 15.9 26.0 23.8 9.1 19.0 35.7 23.2 33.3 25.5 33.8 25.2 21.8 22.2 15.5 14.4 29.4 27.6 42.2 23.0 31.8 44.4 27.0 31.1 26.7 33.5 26.1 15.4 34.0 15.7 30.4 84.1 30.0 57.3 17.1 26.7 14.5 16.6 14.3 16.5 19.1 23.8 13.4 15.3 65.4 13.9 29.0 23.1 18.1 20.4 34.1 34.4 34.9 38.1 34.2 32.8 33.6 33.8 32.9 32.2 34.2 34.3 24.8 35.3 25.9 21.2 40.8 13.0 21.2 27.0 25.6 30.8 29.8 25.3 16.7 22.8 27.2 22.0 31.3 46.3 24.9 42.5 3.9 21.0 51.0 13.9 16.8 20.4 33.5 25.7 15.8 18.8 29.6 22.0 23.0 25.1 22.1 25.6 18.9 13.9 42.6 21.9 16.4 27.1 12.2 37.9 25.9 28.4 21.8 30.9 14.2 16.9 31.5 29.1 25.7 14.6 12.2 25.8 33.2 24.0 18.8 20.5 39.6 10.7 18.9 27.9 26.3 14.6 19.6 81.5 37.1 17.2 14.9 96.7 27.6 30.0 27.0 23.4 TMX2 "PDIA12, TXNDC14" ENSG00000213593 "Thioredoxin related transmembrane protein 2" Q9Y320 11 57712593-57740973 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Lissencephaly, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040282, HPA063763" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "HPA040282: AB_10697715, HPA063763: AB_2685116" "unprognostic (3.66e-3)" "unprognostic (6.96e-2)" "unprognostic (6.69e-3)" "unprognostic (2.73e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (4.11e-4)" "unprognostic (4.48e-2)" "unprognostic (2.98e-1)" "unprognostic (7.26e-3)" "unprognostic (1.90e-2)" "unprognostic (2.22e-1)" "prognostic favorable (1.55e-5)" "unprognostic (5.88e-3)" "unprognostic (4.19e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (3.37e-4)" 52.9 75.1 77.7 37.3 83.0 27.0 50.5 87.4 101.9 43.6 103.3 70.0 56.4 39.4 58.2 62.8 42.7 33.2 71.5 75.0 84.1 78.7 83.4 45.0 31.5 81.7 81.5 40.9 57.7 84.9 43.1 44.0 83.5 50.1 80.8 64.7 49.6 53.8 44.7 45.1 58.3 43.1 84.3 44.9 60.9 30.6 85.5 34.9 57.1 41.3 47.6 48.2 43.8 90.6 122.7 141.4 78.5 143.4 144.8 77.2 86.6 144.2 111.8 140.0 117.9 135.3 205.6 115.1 156.6 116.3 207.1 220.0 203.5 115.4 146.3 83.3 88.9 110.2 105.7 136.8 119.3 156.6 145.5 94.8 166.5 154.8 243.2 76.3 80.6 95.3 194.4 130.9 157.7 62.7 93.0 177.1 153.8 227.7 191.5 124.7 97.9 242.5 174.4 136.4 90.3 129.3 110.2 255.7 168.3 76.7 228.5 102.2 66.7 130.5 84.8 176.1 152.1 127.9 269.5 115.3 146.6 109.3 198.3 37.8 41.5 40.0 34.6 72.4 44.0 36.8 34.4 40.9 40.6 34.9 43.1 43.8 11.2 37.8 86.0 49.7 32.0 45.0 77.7 83.0 87.4 101.9 75.0 84.1 81.7 81.5 83.5 84.3 85.5 90.6 37.9 38.5 34.0 0.0 32.0 32.1 44.9 108.2 19.9 43.4 35.8 28.1 42.6 30.0 60.8 49.7 31.3 108.0 29.9 39.5 43.0 72.4 2.0 19.6 27.4 36.8 28.8 37.6 0.0 43.5 85.6 38.6 23.0 20.7 43.1 29.9 31.8 48.7 62.0 30.3 0.0 49.6 81.4 30.8 21.4 3.6 48.7 31.9 48.0 0.0 37.8 91.1 19.6 0.0 0.0 54.5 32.0 43.6 32.5 49.0 51.4 41.1 37.4 66.7 39.5 36.3 34.5 60.7 62.2 33.6 32.7 99.6 26.6 46.6 75.2 43.6 TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050958, HPA054475" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA050958: AB_2681290, HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" 5.7 2.3 2.6 9.9 2.5 9.3 5.7 2.2 2.7 4.3 2.2 7.0 6.2 2.9 1.1 8.4 4.1 8.2 3.0 2.0 2.4 3.8 5.3 6.6 13.4 3.4 2.8 0.8 2.4 2.7 0.8 7.1 3.1 2.9 7.1 0.2 4.8 2.5 1.5 4.9 6.5 3.9 2.8 6.8 6.5 0.5 3.4 6.4 3.0 2.8 14.0 10.8 5.8 2.8 18.7 33.0 1.7 0.1 1.2 6.4 0.1 3.8 2.3 1.9 5.2 25.4 31.8 42.9 41.9 2.4 9.1 34.6 29.5 47.2 3.1 10.7 0.2 22.7 20.4 14.7 16.2 12.3 20.7 11.0 38.2 41.1 35.0 5.5 21.9 1.4 35.7 14.9 8.9 14.5 0.4 7.8 22.6 33.0 20.0 0.3 0.0 31.2 24.4 39.5 0.9 1.1 9.3 23.0 0.0 6.9 12.3 9.3 31.3 0.1 0.2 1.8 0.1 17.4 26.7 32.7 0.2 3.9 0.5 2.8 6.1 5.7 5.0 2.6 13.8 15.3 16.1 10.2 6.3 19.1 15.7 9.2 0.6 6.1 2.6 0.0 20.8 6.5 2.6 2.5 2.2 2.7 2.0 2.4 3.4 2.8 3.1 2.8 3.4 2.8 21.5 3.2 8.7 0.7 22.3 23.6 20.7 9.1 21.6 0.2 8.2 7.1 1.1 7.2 15.5 11.0 0.0 0.1 3.1 10.1 0.0 10.1 0.1 8.6 1.9 16.6 2.4 1.3 0.4 4.0 0.4 2.2 10.2 23.9 7.6 0.7 2.9 5.1 3.1 0.0 0.4 7.0 8.2 2.2 12.7 0.0 0.0 8.5 3.6 9.4 4.2 0.0 2.1 1.0 0.5 20.3 7.3 0.0 14.0 11.7 4.5 2.9 5.7 0.0 0.0 0.9 1.1 0.0 0.5 25.6 27.4 0.0 12.8 0.1 9.1 27.4 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TPCN1 "FLJ20612, KIAA1169, TPC1" ENSG00000186815 "Two pore segment channel 1" Q9ULQ1 12 113221050-113298585 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 174.3;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 148.6;hTERT-RPE1: 121.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039757 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA039757: AB_10795156" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" "unprognostic (7.34e-2)" "unprognostic (3.07e-2)" "unprognostic (1.32e-3)" "unprognostic (4.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.74e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.23e-1)" "unprognostic (9.08e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-3)" 27.7 48.8 37.7 18.2 54.3 12.5 29.1 70.2 40.5 36.9 48.5 30.4 19.4 30.6 19.3 38.4 35.5 21.7 68.0 34.7 33.4 50.9 27.8 29.5 17.0 43.5 48.3 41.5 52.0 30.8 37.9 18.8 46.6 28.7 19.5 11.5 36.1 27.3 36.7 22.2 31.4 18.6 35.4 28.6 19.1 14.5 44.0 8.5 55.5 24.8 18.2 25.3 26.4 45.9 15.3 45.0 5.1 6.5 38.5 43.3 14.9 21.2 148.6 10.9 13.1 33.5 50.7 34.5 30.9 21.6 35.7 18.8 11.9 37.6 14.7 4.1 9.2 12.9 23.5 18.7 49.9 4.5 28.1 41.5 18.6 21.3 37.2 121.7 16.9 9.8 15.0 11.9 13.5 18.3 1.3 68.3 8.4 18.6 22.3 2.5 6.2 67.3 34.9 54.4 6.5 9.8 17.0 43.2 17.1 10.3 13.9 41.4 7.1 16.0 7.8 22.3 13.3 20.0 13.1 29.6 47.2 10.9 12.3 6.9 14.6 1.3 1.8 2.4 2.0 3.4 2.4 2.3 9.9 5.2 3.3 2.1 0.5 8.5 0.3 5.0 1.2 4.7 37.7 54.3 70.2 40.5 34.7 33.4 43.5 48.3 46.6 35.4 44.0 45.9 8.3 9.6 19.6 174.3 9.0 4.6 6.0 15.4 2.8 19.6 17.0 11.2 34.4 12.8 24.4 27.6 16.7 7.2 3.1 35.9 1.9 13.2 13.2 15.0 21.8 8.1 28.8 9.0 24.5 18.7 3.2 20.2 23.0 19.1 31.1 7.7 15.7 18.3 21.5 50.5 26.6 26.8 14.2 17.9 4.7 11.3 21.5 23.7 7.2 79.6 13.7 17.2 3.1 25.1 61.7 11.5 20.3 21.4 4.6 15.9 29.0 19.7 27.9 13.7 0.0 49.8 18.5 3.6 3.3 10.6 4.0 6.6 5.9 13.2 20.3 22.2 TPTE "CT44, PTEN2" ENSG00000274391 "Transmembrane phosphatase with tensin homology" P56180 21 10521553-10606140 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 201 "testis: 107.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 464.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.7;K-562: 8.2;Karpas-707: 6.4;MCF7: 4.9;PC-3: 4.8;RPMI-8226: 9.0;SuSa: 7.6;U-266/70: 7.7" "HPA049690, HPA068342" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA049690: AB_2680850, HPA068342: AB_2685976" "unprognostic (3.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.4 0.0 4.9 0.0 0.0 1.0 0.0 4.8 0.0 0.0 9.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 7.6 0.0 0.0 0.0 1.8 4.1 2.1 0.0 7.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 20.6 0.1 0.0 0.1 0.0 0.0 0.7 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 13.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.0 13.1 0.0 0.0 464.7 69.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 670.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA023929: AB_1858239" "unprognostic (3.85e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (8.34e-3)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (5.93e-2)" "unprognostic (8.94e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.39e-3)" "unprognostic (3.61e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (7.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" 93.2 82.8 26.6 95.9 28.9 102.3 115.8 27.6 42.1 139.2 47.7 85.4 91.7 93.4 148.5 65.2 78.5 117.7 59.8 24.8 31.1 120.7 190.2 146.3 103.5 32.5 27.9 73.4 175.5 117.3 38.8 146.8 32.4 87.2 79.7 33.3 193.9 86.0 26.7 49.2 93.6 96.7 29.1 90.0 94.7 61.0 29.1 98.6 170.7 54.9 114.3 120.2 47.7 34.5 171.1 172.5 73.6 45.2 352.6 367.8 105.2 302.9 301.7 231.7 279.1 109.9 275.8 169.1 58.5 259.6 91.3 219.3 67.6 262.1 221.8 112.2 76.1 118.5 54.6 125.7 515.4 91.3 66.3 441.5 249.6 114.2 410.8 238.5 196.7 85.0 77.8 430.3 288.6 47.2 210.4 65.7 48.3 132.3 81.0 100.9 55.3 113.8 610.5 160.4 53.4 54.2 195.0 389.0 180.5 103.1 144.1 102.0 195.3 141.0 117.5 162.4 102.0 338.7 140.1 85.5 160.3 92.9 105.0 150.1 97.3 64.9 120.8 107.7 153.5 107.9 132.1 137.6 114.3 87.9 119.6 125.2 28.2 130.7 113.7 190.4 146.8 232.7 26.6 28.9 27.6 42.1 24.8 31.1 32.5 27.9 32.4 29.1 29.1 34.5 138.3 275.7 132.0 19.6 166.4 85.5 85.2 214.0 69.4 23.7 114.2 62.4 43.0 131.5 209.3 178.4 14.6 154.3 200.5 69.3 68.4 174.5 142.8 77.9 140.7 134.3 44.2 59.7 27.4 247.7 236.7 177.0 70.8 186.6 72.4 59.0 137.8 202.9 182.7 23.5 26.1 95.5 156.6 134.9 251.0 222.2 127.4 123.7 202.7 29.0 132.1 65.6 128.8 34.2 40.3 290.5 51.0 94.4 670.6 199.6 78.0 147.0 110.2 32.9 124.9 76.4 99.5 134.8 56.8 72.3 88.5 194.3 154.2 78.2 65.5 130.6 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 11.8 14.5 6.1 5.2 6.0 9.0 12.2 8.3 6.8 13.7 3.6 13.4 5.1 12.0 6.5 10.1 11.8 5.4 14.0 6.0 5.1 13.1 10.9 11.4 6.3 4.5 5.2 18.2 12.8 7.4 16.2 9.3 4.9 13.1 7.1 8.3 11.4 5.4 14.9 15.8 12.6 7.9 1.1 14.9 12.2 22.8 4.5 6.7 17.3 14.6 8.6 11.4 12.7 4.4 8.3 9.7 13.0 10.7 13.0 12.2 24.2 10.3 17.6 11.5 11.0 16.5 9.5 19.4 4.7 20.9 17.0 21.0 15.4 11.0 11.3 9.4 8.2 6.1 19.9 13.6 15.6 9.4 8.0 13.6 8.2 14.3 17.4 11.1 13.0 16.9 11.1 10.2 12.9 15.4 8.3 7.8 17.8 12.1 7.8 9.9 24.5 11.0 5.0 10.7 6.4 10.0 12.7 7.9 6.2 15.2 14.4 5.5 13.8 18.1 10.8 11.4 7.7 5.7 13.8 18.5 10.3 5.2 8.2 2.1 2.3 2.8 3.2 3.8 3.5 0.9 1.7 2.9 1.7 1.2 2.9 2.6 0.9 3.0 1.8 0.9 3.1 1.5 6.1 6.0 8.3 6.8 6.0 5.1 4.5 5.2 4.9 1.1 4.5 4.4 14.7 22.4 27.2 35.3 10.8 7.5 6.2 5.1 9.6 26.6 11.2 9.5 29.2 7.2 10.3 11.0 37.5 15.1 13.5 7.1 13.7 11.7 45.9 18.0 22.2 12.7 16.8 15.8 53.6 7.2 24.0 14.0 14.3 25.8 8.8 27.4 9.7 5.9 9.2 25.2 59.0 10.0 10.2 7.7 7.9 133.1 15.5 12.8 12.4 19.7 10.8 9.7 7.2 30.7 47.8 12.5 7.9 11.3 12.4 9.0 8.9 7.3 16.2 24.4 19.7 19.5 15.4 22.4 20.0 11.8 8.7 21.1 11.9 23.2 10.6 11.0 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Collecting duct cells: 103.0;Distal tubular cells: 189.8;Glandular and luminal cells: 87.5;Proximal tubular cells: 111.1" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 53.0;HUVEC TERT2: 58.3;RH-30: 52.2;RPTEC TERT1: 90.5;RT4: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" 11.9 65.9 4.1 5.3 4.4 0.4 8.7 5.2 5.2 21.4 2.8 24.0 39.4 10.5 14.9 5.0 10.9 20.4 47.7 3.3 4.7 91.6 35.8 45.8 4.5 8.0 6.2 1.7 17.4 10.7 7.5 20.3 5.2 6.8 20.4 1.8 46.8 22.4 3.3 1.6 42.0 11.9 4.6 28.2 22.1 3.9 8.1 2.7 23.4 5.5 4.3 17.5 4.0 3.6 0.0 1.4 15.1 0.2 3.1 1.0 14.7 0.3 0.6 1.2 5.0 2.5 4.0 0.0 10.4 0.4 1.8 0.2 7.7 1.6 1.9 0.0 53.0 2.8 14.5 2.2 8.1 0.1 2.5 0.3 0.0 0.4 0.3 2.1 58.3 0.0 0.7 1.8 6.8 2.0 0.2 0.4 24.5 11.1 9.4 0.1 52.2 2.0 90.5 65.4 12.5 7.4 0.7 1.3 0.0 20.0 8.0 1.9 2.5 12.3 3.8 0.1 6.5 15.8 0.0 0.2 1.7 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.4 5.2 5.2 3.3 4.7 8.0 6.2 5.2 4.6 8.1 3.6 40.0 118.6 45.0 18.6 1.7 2.5 20.3 1.8 14.8 0.0 19.4 3.8 62.5 64.3 19.9 103.0 0.0 40.5 0.0 18.0 189.8 6.8 0.6 63.4 9.0 38.0 9.6 2.7 1.8 7.2 53.5 10.0 14.8 87.5 2.5 1.8 18.2 32.9 4.1 0.0 2.9 16.9 6.1 0.8 3.6 1.5 4.1 1.5 5.4 3.7 0.0 0.5 0.0 10.1 0.4 4.7 30.5 0.7 2.2 9.1 68.3 111.1 5.7 0.1 0.0 11.6 16.6 0.6 8.9 13.8 2.0 24.2 1.9 9.6 35.5 28.3 TSPAN16 "TM-8, TM4-B, TM4SF16" ENSG00000130167 "Tetraspanin 16" Q9UKR8 19 11296139-11326996 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 134.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 4868.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 16.6;eosinophil: 19.1;neutrophil: 37.4" "Lineage enriched" "Detected in many" 17 "granulocytes: 37.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA076551 Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA076551: " "unprognostic (1.06e-1)" "unprognostic (2.82e-2)" "unprognostic (1.73e-2)" "unprognostic (4.74e-3)" "unprognostic (1.53e-1)" "unprognostic (2.06e-3)" "unprognostic (1.37e-1)" "unprognostic (2.21e-1)" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (8.69e-4)" "unprognostic (8.81e-8)" "unprognostic (1.98e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-3)" "unprognostic (2.67e-1)" 0.0 0.0 0.2 0.2 0.1 5.1 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 134.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.6 2.2 19.1 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 37.4 0.0 0.4 0.0 0.0 0.3 0.2 0.1 0.3 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 892.5 0.0 0.1 1.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 4868.3 15.5 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.4 20.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPAN17 "FBX23, FBXO23, TM4SF17" ENSG00000048140 "Tetraspanin 17" Q96FV3 5 176647387-176659054 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030447 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA030447: AB_2673484" "unprognostic (1.70e-2)" "unprognostic (7.92e-2)" "unprognostic (2.91e-1)" "unprognostic (3.47e-2)" "unprognostic (3.97e-2)" "unprognostic (3.71e-3)" "unprognostic (1.21e-3)" "unprognostic (3.82e-1)" "unprognostic (2.30e-1)" "unprognostic (3.60e-1)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.41e-2)" "unprognostic (7.11e-3)" "unprognostic (2.32e-1)" "unprognostic (4.50e-1)" "unprognostic (1.46e-1)" 13.3 40.5 23.0 16.3 24.3 58.2 12.9 18.6 26.2 14.1 21.3 18.0 15.9 12.1 8.4 24.5 13.0 14.7 28.3 24.5 20.1 30.2 20.6 17.7 17.6 18.7 20.0 11.4 26.3 18.2 23.5 12.3 20.6 17.5 13.9 20.8 15.9 10.4 41.6 17.1 17.9 13.3 19.4 22.0 21.1 20.9 21.5 7.0 14.1 25.8 15.2 18.4 13.9 20.6 48.9 48.3 31.8 58.2 43.0 36.8 49.4 35.8 52.0 51.7 51.3 15.0 54.6 21.8 63.5 62.0 106.9 36.4 15.9 83.2 31.6 161.0 33.5 8.3 20.9 17.7 39.1 17.7 29.3 44.0 46.2 41.3 24.9 35.2 71.6 16.6 41.8 22.8 53.1 80.2 3.8 7.8 25.6 47.3 52.5 18.8 27.0 12.1 48.3 35.5 47.9 33.9 38.8 44.6 49.6 26.4 36.7 22.4 56.2 55.9 57.5 42.5 45.8 12.9 17.9 9.7 61.1 37.6 33.3 0.0 2.4 0.6 3.8 2.4 3.1 1.1 2.9 6.2 2.4 1.8 1.9 2.7 0.3 3.0 3.9 0.6 7.5 2.8 23.0 24.3 18.6 26.2 24.5 20.1 18.7 20.0 20.6 19.4 21.5 20.6 11.3 12.8 9.8 5.5 8.0 2.9 11.3 10.7 10.2 23.7 11.5 4.8 16.0 17.2 10.2 11.0 12.5 1.0 11.4 31.1 5.9 37.2 0.8 10.3 6.7 14.1 14.4 51.1 9.5 56.7 18.8 10.5 20.9 12.1 0.0 25.7 10.8 13.5 15.2 1.7 4.2 18.3 14.2 12.4 4.1 1.3 6.8 9.7 7.2 6.5 12.9 7.1 16.5 2.0 3.5 46.6 21.5 7.2 6.6 17.5 29.1 14.6 6.2 24.8 0.0 4.7 11.7 1.9 2.5 12.0 5.4 1.2 14.2 41.1 25.0 13.5 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TSPAN19 ENSG00000231738 "Tetraspanin 19" P0C672 12 85014311-85036277 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 4.3;testis: 4.5" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 382.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.5;SK-BR-3: 1.7;U-266/70: 1.6" "Low region specificity" "Detected in many" HPA057066 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA057066: AB_2683325" "unprognostic (1.94e-1)" "unprognostic (9.81e-4)" "unprognostic (8.57e-2)" "unprognostic (8.37e-2)" "unprognostic (2.33e-1)" "unprognostic (6.57e-2)" "unprognostic (2.26e-3)" "unprognostic (9.52e-2)" "unprognostic (5.09e-3)" "unprognostic (2.22e-1)" "unprognostic (3.78e-2)" 0.1 0.3 0.7 0.3 0.6 1.1 0.0 2.3 1.1 0.2 1.3 0.2 0.4 0.3 0.9 0.1 0.9 0.3 0.1 0.4 0.6 0.4 0.0 2.7 0.3 1.0 0.3 0.2 0.8 0.1 2.0 0.1 0.9 0.5 0.1 4.3 0.0 0.0 0.9 1.3 0.2 0.0 0.2 0.3 0.1 4.5 0.6 0.0 1.8 0.5 0.2 0.1 0.0 1.2 0.3 0.0 0.6 0.2 0.3 0.5 0.8 0.4 0.0 0.0 0.2 0.3 0.0 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.4 0.5 0.0 0.3 0.3 0.9 0.6 0.7 0.4 0.4 0.4 0.2 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.5 1.1 0.0 1.7 0.4 0.2 0.4 0.0 0.5 1.0 0.3 0.5 0.3 1.6 0.0 0.2 1.3 0.0 0.5 0.3 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.2 1.4 0.2 0.1 0.2 0.0 0.0 0.7 0.6 2.3 1.1 0.4 0.6 1.0 0.3 0.9 0.2 0.6 1.2 0.1 3.2 2.0 0.7 0.0 0.1 0.0 18.2 0.0 3.5 0.1 0.1 1.1 0.0 30.3 0.0 8.4 0.0 0.0 0.0 0.0 0.0 72.7 0.6 0.0 0.5 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 14.2 0.0 0.3 6.9 0.0 0.1 0.0 1.0 0.0 5.1 0.0 0.0 3.1 0.0 0.0 0.4 0.1 0.6 0.0 0.1 382.1 9.1 6.6 0.4 5.2 7.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN4 "NAG-2, TETRASPAN, TM4SF7, TSPAN-4" ENSG00000214063 "Tetraspanin 4" O14817 11 842812-867116 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 194.2;Fibroblasts: 168.7;Hofbauer cells: 240.6;Leydig cells: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 146.4;intermediate monocyte: 143.5;myeloid DC: 101.2;NK-cell: 95.6;non-classical monocyte: 39.9" "Group enriched" "Detected in all" 10 "dendritic cells: 101.2;monocytes: 146.4;NK-cells: 95.6" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 142.8" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.39e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (9.49e-2)" "unprognostic (2.41e-2)" "unprognostic (1.29e-2)" "unprognostic (2.61e-2)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" 129.1 37.1 15.8 29.6 14.7 11.8 102.0 17.9 18.7 90.9 44.1 60.3 13.7 84.2 9.2 26.1 85.8 54.1 57.6 15.6 17.4 60.8 37.6 101.4 46.3 17.1 16.7 91.3 32.5 17.6 24.2 61.6 15.6 52.9 10.5 2.5 34.2 33.7 25.7 56.3 43.3 27.5 15.5 85.0 37.0 16.8 18.2 13.2 79.9 22.9 12.7 66.8 71.8 12.9 30.7 238.7 40.8 73.6 61.2 121.4 27.5 153.0 182.5 118.4 81.3 49.5 37.5 2.3 60.4 221.3 68.2 11.3 14.5 145.6 22.2 20.4 17.4 32.5 75.7 71.6 201.4 10.4 38.9 211.5 26.1 42.8 129.0 116.1 78.5 12.5 13.5 184.5 115.8 64.6 7.0 13.0 52.3 39.2 172.7 24.2 29.1 55.4 138.3 2.0 48.0 28.6 75.8 83.6 162.1 17.4 118.5 7.7 116.0 134.2 53.4 27.3 52.2 10.2 1.5 4.5 138.5 11.1 121.8 0.1 146.4 0.1 7.4 143.5 4.6 6.9 3.7 7.2 101.2 5.4 6.2 11.7 3.4 95.6 39.9 7.0 3.6 65.2 15.8 14.7 17.9 18.7 15.6 17.4 17.1 16.7 15.6 15.5 18.2 12.9 194.2 105.8 68.5 6.5 5.6 47.5 22.2 78.8 13.6 9.5 19.4 38.6 9.5 74.4 24.6 31.3 4.2 39.5 8.1 1.7 7.9 82.6 2.1 5.9 43.2 117.3 0.0 12.0 0.6 16.7 31.9 168.7 5.6 10.8 37.2 62.8 97.5 28.2 240.6 13.5 2.9 2.6 4.1 109.9 71.5 7.3 172.7 70.3 147.7 11.2 19.2 43.8 8.2 2.5 0.3 61.3 0.3 95.2 9.3 15.7 0.3 34.7 5.8 6.7 59.2 23.9 67.5 4.7 31.5 6.1 32.8 16.8 10.2 44.7 1.1 6.1 TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 175.4;Excitatory neurons: 362.2;Inhibitory neurons: 248.3;Microglial cells: 195.8;Oligodendrocytes: 587.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.8;T-cells: 6.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 120.8;BJ hTERT+: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-3)" "unprognostic (2.65e-1)" "unprognostic (2.44e-3)" "unprognostic (1.41e-2)" "unprognostic (1.54e-2)" "unprognostic (9.27e-2)" "unprognostic (1.79e-1)" "unprognostic (3.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.83e-5)" "prognostic unfavorable (8.56e-4)" "unprognostic (2.15e-1)" "unprognostic (3.23e-3)" "unprognostic (1.23e-1)" 2.7 1.2 32.5 3.8 37.2 10.4 15.4 62.0 42.7 13.5 21.6 6.4 1.5 19.9 29.2 12.9 7.2 5.0 3.2 41.4 33.5 5.1 0.6 4.3 6.7 32.8 30.8 46.4 0.9 4.0 5.1 7.9 34.5 5.3 3.8 28.1 10.8 8.7 3.8 20.0 3.0 16.4 32.4 9.9 8.9 12.6 33.7 8.5 18.5 3.2 9.2 8.8 9.7 47.4 27.8 10.8 11.0 0.7 41.2 120.8 3.7 111.9 121.4 39.4 48.3 9.6 14.6 0.0 1.1 40.2 21.6 7.0 9.6 52.6 87.7 34.3 5.2 16.9 1.5 0.4 42.5 9.5 0.9 70.1 1.6 72.5 89.1 60.5 64.5 11.3 6.6 29.1 95.3 0.7 29.1 0.1 7.2 23.8 49.2 8.8 10.5 4.2 3.5 8.1 77.5 14.8 2.0 35.4 0.2 3.7 1.2 1.4 66.4 82.7 37.4 29.8 39.9 20.0 31.8 0.0 32.4 22.5 28.8 0.0 0.0 0.0 3.3 0.0 3.6 1.3 4.7 4.7 0.1 3.0 2.4 1.6 0.1 3.8 0.0 0.0 6.0 1.1 32.5 37.2 62.0 42.7 41.4 33.5 32.8 30.8 34.5 32.4 33.7 47.4 4.6 22.4 9.1 129.3 5.6 22.0 24.8 9.1 10.8 63.9 30.9 26.0 2.3 0.0 9.3 29.5 27.1 1.0 17.2 1.4 5.9 2.3 69.6 8.5 45.9 19.7 80.9 175.4 362.2 7.1 0.9 26.0 10.2 15.1 2.5 11.6 8.2 0.9 2.3 111.0 248.3 4.6 20.3 3.4 15.4 91.4 46.0 7.1 28.4 195.8 0.3 21.5 39.1 94.5 587.2 25.3 0.5 17.0 9.3 45.9 0.4 0.6 3.7 41.9 6.6 9.7 13.1 10.1 4.1 33.0 57.7 2.9 31.4 79.7 3.8 44.8 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTC39B "C9orf52, FLJ33868" ENSG00000155158 "Tetratricopeptide repeat domain 39B" Q5VTQ0 9 15163622-15307360 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 64.4;Paneth cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.0;gdT-cell: 2.9;MAIT T-cell: 3.9;memory CD4 T-cell: 4.0;memory CD8 T-cell: 4.6;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.9;NK-cell: 6.3;T-reg: 3.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.0;NK-cells: 6.3;T-cells: 4.7" "Cell line enhanced" "Detected in many" "HEL: 40.9;RT4: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063162 Approved "Endoplasmic reticulum" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA063162: AB_2684952" "unprognostic (1.64e-1)" "unprognostic (9.32e-3)" "unprognostic (1.47e-2)" "unprognostic (7.89e-2)" "unprognostic (7.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.12e-2)" "prognostic favorable (9.64e-6)" "unprognostic (5.99e-2)" "unprognostic (4.77e-2)" "unprognostic (1.59e-1)" "unprognostic (6.89e-2)" "prognostic favorable (4.08e-7)" "unprognostic (3.31e-3)" "unprognostic (2.12e-2)" "unprognostic (5.19e-2)" "unprognostic (1.48e-1)" 1.9 2.6 2.9 4.0 2.5 1.5 4.8 10.8 7.0 4.3 1.8 6.7 5.7 3.5 1.9 8.8 3.3 6.9 1.3 1.5 4.6 9.0 5.4 4.6 6.1 7.0 2.9 2.9 3.9 1.9 3.9 1.2 7.2 2.3 5.6 2.9 3.0 1.9 1.8 9.6 5.6 4.2 2.5 3.8 5.5 5.7 4.7 3.4 2.6 1.3 6.0 3.6 4.7 2.9 3.9 0.8 1.2 5.6 5.3 9.9 1.2 5.0 9.1 3.9 9.3 0.8 1.6 0.0 0.6 6.3 4.6 3.4 0.9 6.2 3.3 4.5 0.8 40.9 1.7 7.3 8.8 0.0 0.8 9.7 4.7 8.1 9.0 2.8 5.6 3.3 0.1 9.1 10.0 1.3 2.2 0.2 1.6 12.3 1.2 0.4 3.0 1.9 8.3 23.0 2.9 0.5 1.2 2.9 0.9 1.8 12.7 2.5 4.2 2.2 1.8 3.1 1.4 0.1 0.1 0.0 2.1 0.5 1.1 2.0 0.7 0.9 2.9 0.5 3.9 0.2 4.0 4.6 0.4 0.6 4.7 2.9 0.4 6.3 0.7 0.1 3.8 2.5 2.9 2.5 10.8 7.0 1.5 4.6 7.0 2.9 7.2 2.5 4.7 2.9 7.5 12.8 19.8 10.4 7.0 17.3 7.8 19.1 10.8 25.5 9.0 4.4 4.1 10.0 15.8 7.3 0.0 3.2 18.0 40.6 17.6 6.6 43.2 11.8 10.1 7.4 12.7 0.4 44.0 21.8 1.1 10.0 22.4 7.7 29.1 3.6 7.5 11.6 4.1 13.5 64.4 16.1 24.4 3.1 9.2 33.2 7.2 16.7 7.2 12.2 2.9 14.9 11.3 24.6 2.3 10.5 65.0 12.8 5.5 11.5 30.3 35.5 25.3 4.3 0.0 9.4 12.4 4.7 3.0 8.6 21.5 4.1 22.3 6.8 17.3 14.4 TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.2;retina: 143.2" "Cell type enhanced" "Detected in many" "Early spermatids: 149.8;Hepatocytes: 169.3;Late spermatids: 320.0;Rod photoreceptor cells: 241.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 19.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 115.9" "Lineage enriched" "Detected in all" 4 "T-cells: 115.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 13: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA065705: AB_2685538, HPA065713: AB_2685542" "prognostic favorable (1.48e-4)" "unprognostic (6.37e-2)" "unprognostic (3.66e-1)" "unprognostic (9.97e-2)" "unprognostic (4.37e-2)" "unprognostic (2.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" "unprognostic (8.94e-3)" "unprognostic (4.48e-3)" 21.1 30.5 6.7 12.3 6.4 36.3 18.9 3.2 26.2 20.1 10.8 10.9 9.1 15.6 7.4 16.0 18.6 23.6 7.2 19.9 4.5 6.1 94.2 15.1 19.0 1.6 2.5 10.2 15.8 1.9 20.1 2.7 0.6 20.0 7.4 143.2 25.2 5.4 10.2 56.1 13.4 8.3 2.1 13.2 12.8 33.3 3.6 15.4 7.1 1.6 21.3 13.3 19.6 5.3 12.6 10.4 6.1 3.7 38.3 39.8 22.9 16.4 39.0 13.9 13.5 1.3 6.8 19.7 16.8 30.4 11.1 15.8 12.3 16.5 10.9 28.7 13.1 6.6 50.6 26.3 7.7 31.4 15.3 33.4 21.8 8.4 11.7 26.9 1.1 14.6 0.1 0.2 8.7 10.7 4.9 10.0 14.5 5.5 25.1 28.1 9.5 7.8 14.7 19.7 15.9 12.4 34.5 10.6 11.4 6.5 8.2 10.6 8.3 11.8 9.6 8.7 8.7 0.4 0.1 32.0 16.0 32.9 8.3 2.4 5.4 0.2 32.8 6.1 84.0 16.4 71.7 40.3 7.8 10.0 30.0 25.0 1.5 18.5 5.2 27.8 115.9 13.1 6.7 6.4 3.2 26.2 19.9 4.5 1.6 2.5 0.6 2.1 3.6 5.3 6.9 0.0 3.4 13.7 23.0 46.0 17.1 10.1 30.1 14.7 28.6 24.1 3.0 64.3 5.0 7.3 45.9 0.7 52.0 2.0 0.0 14.2 149.8 72.9 34.9 7.0 4.2 20.6 114.3 11.5 15.2 16.5 15.8 30.0 2.5 11.5 4.6 169.3 12.6 13.5 80.3 9.4 18.3 26.6 44.5 320.0 11.1 21.5 14.2 20.6 18.9 27.8 38.1 41.7 2.3 8.9 1.5 7.9 7.1 20.8 11.4 1.3 16.7 241.5 0.0 5.2 6.7 42.4 8.0 26.8 86.1 0.5 95.9 9.2 9.0 20.1 TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.9;choroid plexus: 35.6;testis: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Bipolar cells: 138.6;Muller glia cells: 653.4;Oligodendrocytes: 97.5;Rod photoreceptor cells: 155.3" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;AN3-CA: 11.7;U-2 OS: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" 0.9 0.9 64.3 0.0 67.9 0.0 3.5 64.0 80.9 4.0 35.6 10.0 0.2 1.6 0.0 1.1 10.4 0.2 3.6 57.6 59.7 1.2 0.7 0.2 0.0 69.4 66.5 1.5 19.4 0.0 17.7 0.0 63.5 3.5 0.0 3.2 3.6 0.4 3.3 5.9 2.6 0.0 67.6 1.4 2.5 53.4 69.3 0.0 0.3 0.0 0.0 1.7 4.2 66.8 0.1 0.0 7.9 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.3 67.9 64.0 80.9 57.6 59.7 69.4 66.5 63.5 67.6 69.3 66.8 0.4 3.2 0.6 257.6 0.4 0.8 1.2 0.6 0.0 138.6 44.3 42.2 1.3 4.3 3.0 0.0 20.9 0.9 1.3 0.2 0.0 30.4 3.9 0.3 0.9 2.8 1.2 0.0 26.4 0.6 0.7 1.5 0.0 0.7 0.0 13.7 0.7 0.1 0.3 10.1 3.3 0.0 0.0 0.0 1.5 4.8 1.8 0.3 23.2 19.7 0.3 653.4 0.0 48.2 97.5 2.2 0.0 0.7 0.1 1.9 0.4 0.7 2.8 155.3 6.6 2.3 7.8 2.2 5.1 0.0 0.9 4.2 0.6 0.5 0.3 1.9 TTYH3 KIAA1691 ENSG00000136295 "Tweety family member 3" Q9C0H2 7 2631986-2664802 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.0;Kupffer cells: 85.0;Melanocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 10.0;non-classical monocyte: 8.4" "Lineage enriched" "Detected in many" 4 "monocytes: 10.0" "Cell line enhanced" "Detected in all" "U-2 OS: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053520 Uncertain NA NA 55000 "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" "HPA053520: AB_2682176" "unprognostic (2.53e-2)" "unprognostic (6.65e-3)" "unprognostic (3.86e-3)" "unprognostic (1.35e-1)" "unprognostic (5.25e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (2.53e-5)" "unprognostic (5.53e-2)" "unprognostic (1.96e-1)" "unprognostic (8.59e-3)" "unprognostic (5.40e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (2.58e-5)" "unprognostic (7.90e-2)" "unprognostic (5.45e-2)" "unprognostic (1.03e-1)" "unprognostic (8.85e-2)" 25.6 29.4 31.6 30.7 32.7 11.8 16.3 43.3 39.3 19.0 1.8 15.8 19.9 18.7 1.9 7.7 16.7 18.3 12.4 24.1 8.9 43.3 37.4 25.6 19.4 11.4 18.4 15.0 9.6 4.6 14.2 23.8 9.0 20.9 6.7 5.3 25.4 7.3 3.9 12.0 27.7 10.6 4.7 40.8 13.3 14.4 33.8 11.7 21.6 1.7 7.3 14.6 11.4 10.7 43.8 84.9 88.0 123.7 24.2 21.7 98.5 69.4 61.8 29.8 34.9 35.3 30.9 3.6 82.4 66.1 78.8 19.3 12.7 31.5 8.4 5.9 42.9 21.8 17.9 98.7 32.3 4.5 13.2 52.0 15.1 32.0 8.3 55.5 99.4 21.6 6.7 4.7 20.1 25.5 16.1 47.0 112.7 61.7 32.9 66.3 63.7 4.1 47.0 47.0 36.8 185.1 42.8 8.2 40.3 58.1 22.3 117.5 117.9 69.3 205.4 40.9 78.6 8.0 5.3 12.1 50.0 16.1 152.7 0.0 4.9 1.5 0.2 10.0 0.2 0.3 0.1 0.1 2.2 0.3 0.3 0.0 0.5 0.3 8.4 1.0 0.2 3.4 31.6 32.7 43.3 39.3 24.1 8.9 11.4 18.4 9.0 4.7 33.8 10.7 8.6 0.0 4.2 38.5 4.8 6.5 1.8 12.9 2.2 9.0 10.2 7.1 2.7 18.6 8.8 9.2 4.2 1.8 2.9 9.6 3.9 20.3 0.5 2.8 12.8 21.0 7.8 1.7 22.4 5.2 28.8 9.0 7.1 6.0 2.5 19.4 15.4 21.1 135.0 30.3 25.4 20.5 8.2 85.0 32.6 5.2 8.1 52.4 56.9 17.8 30.7 4.0 2.1 8.5 6.1 20.2 2.7 3.8 1.5 5.0 28.3 32.2 3.8 2.2 6.6 2.2 8.0 1.7 2.3 1.2 3.7 2.5 3.8 4.9 11.2 3.1 TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.9;Extravillous trophoblasts: 321.8;Syncytiotrophoblasts: 783.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" 23.3 68.8 18.7 8.4 18.4 0.1 28.3 22.3 17.1 25.0 46.6 14.5 9.3 31.9 100.8 11.8 57.6 16.7 34.9 17.1 48.2 25.2 6.9 18.4 6.8 8.9 11.6 73.6 35.0 54.0 69.6 80.5 8.9 46.4 15.5 40.9 12.1 29.7 4.5 8.2 8.2 32.5 7.7 5.3 10.8 23.2 21.0 7.5 9.5 5.7 5.6 34.0 13.0 8.0 52.1 38.4 104.3 96.7 125.2 126.7 0.2 74.9 168.8 85.2 139.3 0.1 0.1 0.7 24.5 105.9 92.4 39.3 37.5 76.1 116.0 0.1 49.8 0.0 30.1 6.0 51.9 0.2 5.6 111.8 22.8 121.0 43.1 113.7 6.9 15.9 70.9 15.6 123.2 41.2 20.6 0.4 49.2 0.0 33.5 24.8 88.7 0.3 108.3 127.1 40.7 74.6 0.0 40.6 56.5 76.2 49.8 0.2 29.0 71.9 71.3 31.3 36.5 0.0 10.0 0.4 1.2 0.0 102.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.4 22.3 17.1 17.1 48.2 8.9 11.6 8.9 7.7 21.0 8.0 88.6 0.0 10.3 13.4 0.6 9.9 61.1 123.5 63.7 50.4 40.0 52.1 47.5 18.6 47.0 79.1 8.4 472.9 0.9 2.1 17.6 179.0 11.5 100.8 48.6 36.2 95.7 0.0 141.0 12.2 321.8 53.4 7.7 35.0 1.3 39.3 7.5 0.0 41.8 32.0 155.3 26.3 95.6 0.0 6.3 7.6 34.8 1.5 24.9 24.4 1.6 35.9 0.0 61.3 3.9 23.8 4.1 23.0 2.6 63.8 0.0 23.7 172.4 28.1 39.5 2.0 49.7 60.9 47.4 26.2 4.1 783.8 1.6 46.6 7.8 51.4 TVP23A "FAM18A, YDR084C" ENSG00000166676 "Trans-golgi network vesicle protein 23 homolog A" A6NH52 16 10760919-10818794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 29.0;Granulosa cells: 92.1;Inhibitory neurons: 28.4;Langerhans cells: 47.6;monocytes: 29.1;Oligodendrocyte precursor cells: 23.6" "Cancer enhanced" "Detected in some" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;NTERA-2: 1.3;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060582 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA060582: AB_2684326" "unprognostic (6.70e-4)" "unprognostic (1.64e-3)" "unprognostic (2.38e-2)" "unprognostic (8.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.39e-5)" "unprognostic (4.96e-2)" "unprognostic (4.68e-2)" "unprognostic (4.42e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-2)" "unprognostic (2.42e-1)" "unprognostic (8.78e-7)" "unprognostic (1.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.87e-2)" "unprognostic (2.87e-4)" 1.0 1.2 4.5 1.1 4.8 1.8 0.6 3.0 5.7 1.6 1.0 0.8 0.8 0.9 0.5 0.6 1.5 0.9 1.4 4.4 4.4 1.0 1.1 0.9 2.0 3.3 3.8 3.6 1.0 0.0 2.2 0.1 3.8 2.0 0.2 2.2 0.7 0.9 0.5 0.7 1.3 0.6 2.8 1.7 0.8 1.0 4.3 0.8 0.9 0.0 0.6 0.7 0.8 3.6 0.1 0.4 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.2 0.1 0.6 0.3 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.2 0.2 0.3 1.3 0.1 0.0 0.6 0.1 0.2 0.0 0.4 0.2 2.1 0.1 0.2 0.0 0.2 0.2 0.1 0.2 0.3 0.2 0.3 0.1 1.0 0.1 0.3 0.3 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.6 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 4.5 4.8 3.0 5.7 4.4 4.4 3.3 3.8 3.8 2.8 4.3 3.6 0.2 0.0 1.8 5.2 0.8 1.1 0.0 0.1 0.6 6.4 0.1 0.4 0.6 0.0 0.1 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.7 0.6 0.4 0.4 0.0 0.0 29.0 0.6 0.6 3.3 0.0 0.3 0.0 92.1 0.0 0.2 0.8 1.7 28.4 0.0 0.0 1.0 47.6 0.3 2.8 4.5 1.8 1.9 29.1 4.7 0.0 23.6 1.1 0.3 0.0 1.5 0.2 0.0 0.0 1.3 0.2 1.3 0.0 0.2 3.6 2.2 3.1 0.1 1.0 1.4 0.5 0.1 0.1 0.1 TVP23B "CGI-148, FAM18B, FAM18B1, YDR084C" ENSG00000171928 "Trans-golgi network vesicle protein 23 homolog B" Q9NYZ1 17 18781111-18806714 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA019585: AB_1848385, HPA065603: AB_2685517" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (9.32e-3)" "unprognostic (1.13e-2)" "unprognostic (8.51e-2)" "unprognostic (2.37e-1)" "unprognostic (3.32e-2)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (3.54e-1)" "unprognostic (5.27e-1)" "unprognostic (7.78e-2)" "unprognostic (8.55e-2)" 26.4 43.2 11.1 20.0 11.7 19.9 30.3 12.8 15.1 38.2 23.3 25.8 29.9 26.5 40.4 52.3 34.5 30.4 22.8 10.6 13.5 31.0 44.0 20.8 25.4 12.3 13.0 30.1 33.6 47.8 32.7 29.6 13.0 33.5 31.2 32.1 34.3 24.4 17.3 19.3 23.8 21.7 13.1 17.4 40.5 34.9 12.4 20.4 46.9 16.2 31.4 32.7 34.2 13.3 55.0 63.8 23.6 26.2 68.8 60.9 56.1 93.5 75.0 42.8 54.6 37.6 38.7 17.9 33.9 60.3 42.6 74.1 19.2 40.2 63.2 44.3 39.7 17.0 47.1 46.3 48.0 13.0 35.6 31.6 95.7 46.0 67.7 78.7 36.0 12.6 14.0 13.1 62.9 27.6 17.2 18.3 11.0 99.2 25.6 17.4 52.1 23.1 52.7 36.0 13.4 29.9 49.8 32.4 60.4 129.0 46.9 19.7 41.6 32.7 28.1 69.8 57.5 25.9 31.7 9.5 50.2 22.2 68.2 54.4 20.4 44.6 29.7 27.4 40.5 32.1 33.0 32.1 17.3 26.9 34.8 34.8 24.2 32.3 27.1 27.9 26.3 32.1 11.1 11.7 12.8 15.1 10.6 13.5 12.3 13.0 13.0 13.1 12.4 13.3 10.0 12.8 13.2 9.4 29.4 25.2 28.1 70.4 54.7 8.6 16.5 9.7 4.2 10.0 42.4 9.2 10.4 13.3 15.7 8.5 11.7 13.9 8.6 21.7 16.1 12.9 6.1 17.2 8.1 11.6 30.3 19.1 40.2 16.2 22.2 7.1 11.0 10.3 10.0 1.7 8.8 14.6 44.7 10.3 10.7 4.2 16.8 16.0 26.6 11.2 9.1 9.1 17.5 14.1 12.8 16.5 10.7 17.0 62.1 28.5 12.0 14.0 60.0 11.1 13.1 9.0 17.0 50.8 43.0 65.5 30.5 26.1 23.7 8.9 8.6 32.4 TVP23C "FAM18B2, MGC8763" ENSG00000175106 "Trans-golgi network vesicle protein 23 homolog C" Q96ET8 17 15502264-15563595 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "HPA019585: AB_1848385, HPA065603: AB_2685517" "unprognostic (2.87e-3)" "unprognostic (5.35e-3)" "unprognostic (1.01e-1)" "unprognostic (8.39e-3)" "unprognostic (1.33e-3)" "unprognostic (3.00e-1)" "unprognostic (6.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.01e-1)" "unprognostic (1.10e-3)" "unprognostic (3.43e-1)" "unprognostic (8.09e-5)" "unprognostic (2.42e-2)" "unprognostic (1.61e-1)" "unprognostic (3.50e-1)" "unprognostic (2.45e-2)" 3.8 6.6 4.2 2.3 3.5 10.9 4.5 6.9 3.9 7.4 8.0 3.3 2.1 4.6 3.3 5.9 4.2 2.4 4.1 3.1 4.7 6.4 3.9 4.6 2.8 5.5 5.2 8.8 5.2 3.7 10.1 4.0 3.9 6.4 2.1 4.1 6.0 2.0 3.0 4.5 3.8 2.2 3.0 4.7 3.8 5.2 5.2 1.9 6.8 1.5 2.4 3.9 5.7 6.5 8.3 7.3 2.7 3.9 3.5 1.8 4.2 6.9 11.6 12.1 14.2 9.3 3.3 0.0 3.7 5.8 6.6 3.5 8.4 5.2 8.6 5.2 4.5 5.5 6.7 13.2 3.2 2.0 5.0 2.4 2.0 12.2 7.2 10.2 11.1 2.9 6.7 3.5 5.3 2.7 3.5 5.6 3.0 3.3 2.5 0.6 0.3 0.4 3.3 4.8 0.9 2.3 8.7 1.0 1.8 11.3 4.8 1.1 7.9 2.0 2.8 2.9 2.2 2.2 2.1 0.0 2.3 0.0 1.8 11.3 1.8 8.4 3.3 4.1 4.5 6.4 4.5 5.0 3.0 4.6 5.5 5.1 2.9 5.0 2.9 3.3 4.7 4.3 4.2 3.5 6.9 3.9 3.1 4.7 5.5 5.2 3.9 3.0 5.2 6.5 3.5 3.2 8.2 0.0 2.9 4.0 5.4 4.3 4.6 5.9 4.2 2.7 17.2 0.0 7.0 0.0 14.6 5.9 5.5 3.8 1.9 2.9 1.3 6.6 4.4 5.8 1.8 3.0 0.0 0.6 11.7 5.6 6.6 6.5 2.5 6.2 1.8 0.7 3.2 6.7 0.0 4.0 6.1 1.9 3.3 0.9 3.4 2.3 1.8 0.0 2.4 2.6 4.1 0.0 0.0 1.6 2.9 2.2 9.2 5.2 4.3 0.8 4.3 10.5 0.0 3.3 5.6 10.0 7.9 5.5 2.8 5.5 4.7 7.2 4.9 7.0 UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" 15.3 13.3 9.0 18.2 9.3 19.6 20.0 7.3 9.2 21.3 9.9 21.5 30.7 19.9 17.9 28.6 27.6 22.6 27.3 10.1 8.4 21.9 27.7 16.9 25.4 10.9 9.6 19.1 17.4 30.0 2.7 29.4 8.8 18.4 22.9 7.6 25.8 17.3 39.0 30.6 23.3 19.7 11.6 20.8 17.7 26.2 12.6 29.3 30.0 38.9 27.3 23.9 8.6 8.8 51.8 26.8 22.4 33.9 52.2 62.8 56.3 25.9 73.3 40.3 36.4 29.2 108.7 19.9 43.8 34.8 27.0 49.2 28.8 41.1 22.0 33.8 33.7 37.2 16.9 22.5 48.7 48.2 28.1 45.9 54.9 24.6 71.0 54.6 38.8 39.6 31.1 13.3 31.6 14.3 32.1 15.3 32.6 104.0 27.0 27.6 24.9 15.2 32.7 29.6 25.2 40.3 21.0 67.8 41.4 39.4 41.5 148.7 30.3 21.9 19.0 20.1 29.5 16.3 12.0 6.6 42.9 71.9 38.3 64.6 53.7 41.9 61.3 57.3 87.3 48.1 53.8 62.6 46.2 55.2 73.6 74.5 48.8 84.6 57.5 57.3 40.2 88.1 9.0 9.3 7.3 9.2 10.1 8.4 10.9 9.6 8.8 11.6 12.6 8.8 28.7 6.4 19.1 58.8 45.3 27.1 26.0 41.7 40.5 27.3 31.2 24.3 23.8 21.5 29.4 23.9 27.1 111.6 48.5 37.3 23.5 44.1 26.0 24.5 21.7 26.4 8.4 31.3 110.9 34.9 84.6 31.6 19.4 21.9 22.2 34.3 17.9 29.1 48.5 32.0 103.0 30.1 40.7 39.1 121.4 22.0 35.1 88.4 30.2 81.5 35.7 48.8 69.0 82.0 73.3 29.0 32.6 50.8 11.7 48.7 48.0 22.6 31.6 21.2 32.9 24.7 32.1 66.2 35.1 31.7 33.1 132.4 66.0 54.4 39.1 34.4 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.2;tongue: 87.1" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 305.1;Inhibitory neurons: 302.0;Oligodendrocyte precursor cells: 232.2;Oligodendrocytes: 288.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 14.2 12.4 4.4 7.7 5.8 7.4 9.2 5.9 8.5 10.9 2.8 8.8 8.1 10.1 6.9 12.8 8.4 9.3 29.4 8.0 3.3 15.2 21.0 8.8 7.2 2.4 2.7 10.2 11.9 21.5 2.1 8.7 3.3 13.1 8.5 21.2 11.5 10.3 71.2 9.2 7.5 11.1 3.2 8.8 9.3 9.7 3.4 9.5 17.9 87.1 7.3 11.0 2.3 8.4 14.8 12.4 12.9 17.1 25.0 19.7 10.8 26.1 15.0 14.7 11.8 19.1 9.1 16.7 22.2 20.5 12.0 19.0 15.5 13.2 18.2 17.4 13.4 61.1 12.6 20.3 12.4 20.4 18.9 11.9 12.1 19.3 12.9 11.7 14.8 8.3 32.4 17.6 25.6 14.0 13.3 10.0 10.1 14.9 10.2 12.6 21.1 17.8 10.5 20.5 25.1 13.7 18.4 16.7 10.6 10.2 10.9 11.4 18.9 22.1 9.0 17.5 16.7 14.2 11.9 15.1 18.2 11.8 12.5 0.0 0.6 0.5 0.9 0.6 1.3 0.6 0.5 0.8 0.9 0.3 0.9 1.2 0.6 0.8 0.5 0.7 1.0 0.4 4.4 5.8 5.9 8.5 8.0 3.3 2.4 2.7 3.3 3.2 3.4 8.4 19.0 44.8 26.9 162.6 16.3 25.9 12.4 14.8 20.5 46.3 15.8 8.9 109.7 17.2 20.0 12.9 81.3 19.7 22.9 17.1 3.9 8.7 7.6 16.8 21.9 26.4 16.7 24.4 305.1 11.0 8.4 22.2 23.4 22.0 16.5 22.7 30.4 39.0 10.2 63.9 302.0 11.3 22.4 20.9 18.7 10.2 25.7 18.7 16.0 110.5 18.7 61.7 14.4 232.2 288.0 10.7 15.0 19.2 21.3 20.9 15.3 10.0 13.4 51.5 26.3 29.0 21.8 12.4 8.6 22.9 29.0 23.0 18.1 17.3 13.2 17.2 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 352.3;Excitatory neurons: 108.6;Inhibitory neurons: 99.2;Late spermatids: 405.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 2.7 3.1 1.6 2.9 2.1 8.5 2.5 0.4 1.7 8.5 16.9 1.6 1.2 6.6 4.5 1.5 9.0 1.9 8.6 2.3 2.5 3.9 2.1 3.5 3.0 6.9 7.6 2.1 2.0 8.0 2.9 2.7 3.9 2.2 1.7 6.0 1.7 2.4 0.4 2.1 2.0 3.5 5.6 2.0 2.4 23.4 2.5 3.0 4.9 0.4 2.7 1.9 3.7 2.1 8.3 2.9 2.8 3.8 1.1 1.7 4.8 2.7 2.7 3.2 3.0 1.0 2.3 9.5 1.6 6.3 3.5 4.1 3.7 2.1 2.9 1.5 1.0 2.1 5.7 3.3 4.1 6.5 1.8 1.6 2.3 16.1 3.2 4.4 2.2 6.4 2.1 7.5 2.3 6.4 8.1 4.9 3.4 2.1 3.4 1.7 9.1 4.5 7.2 7.6 1.6 10.3 3.1 1.3 2.8 1.8 3.1 2.0 6.6 2.0 2.4 14.2 2.5 4.5 9.0 3.9 11.5 6.3 2.5 3.7 3.7 4.0 5.0 4.3 4.1 3.7 5.3 4.5 3.3 4.7 4.0 5.7 6.6 1.8 2.3 3.3 7.7 3.0 1.6 2.1 0.4 1.7 2.3 2.5 6.9 7.6 3.9 5.6 2.5 2.1 6.4 9.6 6.9 84.9 11.2 2.0 3.0 4.0 5.2 5.6 5.7 4.6 14.8 4.3 5.1 3.7 54.2 3.1 9.9 2.0 0.0 3.4 352.3 45.3 27.4 6.0 1.8 2.1 108.6 2.4 4.1 8.7 10.2 7.5 1.3 49.6 1.8 6.6 7.3 11.8 99.2 1.2 2.0 3.1 4.0 405.2 6.5 6.9 0.0 80.6 5.9 10.4 3.1 49.8 62.0 3.0 0.7 4.1 5.1 0.9 1.1 5.9 47.3 26.7 6.6 4.4 10.5 38.9 9.6 3.3 3.7 4.2 10.8 3.6 1.9 1.2 UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Predicted membrane proteins" "Protein transport, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA027009: AB_1858620" "prognostic unfavorable (4.79e-4)" "unprognostic (3.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (5.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "unprognostic (7.12e-3)" "unprognostic (4.82e-3)" 36.6 49.1 46.3 34.2 48.2 36.8 45.8 48.8 57.3 38.1 53.6 35.0 37.9 46.3 69.2 30.9 42.7 36.2 38.7 46.2 48.3 52.5 46.9 38.6 41.4 48.5 46.6 44.2 42.0 82.4 41.4 52.2 49.1 41.3 43.2 60.0 56.0 45.4 31.6 39.9 34.4 38.7 49.0 39.3 45.5 48.9 47.2 36.6 64.1 35.9 42.6 37.8 30.5 54.3 55.2 35.6 65.2 44.3 95.7 82.6 73.0 51.2 71.8 61.9 54.2 54.5 64.0 16.6 75.2 44.1 94.0 52.0 45.9 41.5 50.9 56.4 46.2 37.5 47.3 89.4 103.0 71.7 56.7 54.6 92.5 33.1 60.4 71.5 55.1 43.3 61.2 50.2 63.5 39.2 31.7 80.3 49.6 46.1 41.7 20.1 47.3 58.8 68.9 48.6 24.2 35.6 35.9 47.3 86.5 75.8 40.7 91.9 42.7 67.4 41.3 34.5 35.0 76.1 63.2 44.2 63.6 51.7 60.1 61.6 54.3 66.7 50.6 54.9 43.9 52.8 42.2 47.9 54.9 48.1 46.2 52.9 45.3 58.5 51.4 51.3 37.4 44.2 46.3 48.2 48.8 57.3 46.2 48.3 48.5 46.6 49.1 49.0 47.2 54.3 45.3 25.6 31.0 13.7 35.7 47.2 51.2 139.4 42.7 36.7 46.7 40.8 39.5 38.6 85.8 35.0 16.7 118.6 41.2 27.4 33.2 52.3 47.7 38.3 35.3 48.3 21.6 19.1 21.2 53.2 77.1 58.9 19.4 30.7 27.3 23.7 47.2 33.9 73.2 33.7 24.1 34.1 85.5 31.3 33.3 29.9 54.7 33.0 44.4 19.7 41.7 84.6 48.4 19.1 25.8 40.7 33.0 74.9 51.0 75.7 29.0 46.6 73.8 49.8 46.0 45.0 58.9 215.1 58.7 34.6 49.7 152.6 29.2 39.1 30.1 44.6 VEZT DKFZP761C241 ENSG00000028203 "Vezatin, adherens junctions transmembrane protein" Q9HBM0 12 95217746-95302799 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004811, HPA017066" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA004811: AB_1080563, HPA017066: AB_1858742" "unprognostic (3.91e-1)" "unprognostic (6.34e-3)" "unprognostic (3.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.28e-1)" "unprognostic (9.93e-2)" "unprognostic (4.18e-1)" "unprognostic (1.10e-3)" "unprognostic (3.37e-3)" "prognostic unfavorable (1.93e-5)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.51e-1)" "unprognostic (4.06e-1)" "unprognostic (5.02e-2)" 7.3 9.9 7.7 5.8 8.0 3.3 8.9 11.3 9.9 9.2 3.1 7.6 5.8 8.2 9.6 6.6 7.7 7.4 9.5 8.5 8.6 6.9 6.2 7.8 6.4 4.4 5.7 11.2 9.0 8.6 13.4 9.4 5.7 9.6 6.3 20.3 5.4 7.6 23.8 10.3 5.9 7.1 4.0 4.1 5.6 4.5 6.9 6.6 18.9 21.2 6.4 7.5 8.5 7.1 14.4 12.9 18.0 9.5 14.7 9.2 6.8 10.3 13.3 8.7 12.9 4.8 6.6 18.6 6.5 8.8 4.3 7.4 13.3 9.2 15.2 12.6 7.3 7.2 3.3 5.2 7.5 14.2 4.1 12.7 15.6 7.6 21.9 19.0 17.1 8.9 4.2 7.0 7.6 4.0 12.4 6.7 9.2 4.5 13.1 11.1 8.4 6.0 23.8 10.3 12.1 10.6 10.1 14.9 4.9 15.8 18.4 2.4 13.9 7.2 2.8 3.5 5.8 6.8 11.4 16.3 2.8 5.1 3.8 0.2 1.5 0.5 1.5 1.6 2.1 2.5 2.2 0.9 2.0 1.8 1.0 0.9 0.1 1.1 0.4 0.8 1.8 0.5 7.7 8.0 11.3 9.9 8.5 8.6 4.4 5.7 5.7 4.0 6.9 7.1 36.5 70.5 49.3 88.8 31.1 77.8 58.1 37.5 63.2 67.9 46.3 28.6 49.0 37.1 44.5 33.1 85.5 39.6 26.3 40.0 9.8 50.1 16.5 30.1 48.4 44.6 38.4 22.1 151.8 45.2 22.3 31.0 27.5 53.8 29.2 59.9 47.8 36.7 21.6 62.2 149.1 36.1 30.5 27.1 37.5 11.4 32.6 23.2 37.4 74.9 25.2 24.1 14.4 101.0 98.4 76.4 39.4 33.1 40.5 54.6 33.0 21.5 33.1 146.6 6.6 39.0 37.3 39.4 21.3 57.8 72.5 110.7 29.1 32.7 24.9 71.7 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 54.0 11.1 8.1 11.2 9.0 4.3 23.7 8.3 12.1 12.0 3.7 12.4 11.1 12.3 10.6 12.5 10.0 10.0 12.1 10.1 9.2 10.0 22.9 18.4 8.7 18.1 10.5 17.3 9.7 33.6 6.7 12.0 10.5 12.0 12.5 11.5 10.9 12.4 21.6 12.8 11.6 11.6 8.9 7.4 12.8 9.1 8.5 9.7 13.9 15.3 8.7 11.9 9.6 9.6 46.8 29.5 23.4 29.5 72.6 28.6 42.3 49.5 31.8 29.0 29.1 28.7 44.9 40.4 39.0 35.7 43.9 31.2 33.6 20.1 47.9 25.5 33.1 27.6 25.4 24.7 35.4 38.7 20.3 23.2 25.3 29.5 40.7 22.5 29.2 22.6 59.0 30.0 34.9 18.3 31.8 44.8 56.1 43.8 22.0 34.5 34.0 50.5 28.0 18.5 28.0 39.8 38.3 68.5 21.8 32.8 34.5 29.5 33.3 46.6 32.0 29.5 51.0 26.9 47.1 46.1 28.6 43.0 41.6 2.0 1.1 2.7 1.2 1.1 1.0 1.3 1.5 1.4 1.3 1.1 0.9 0.9 1.3 2.9 2.2 3.5 1.5 0.7 8.1 9.0 8.3 12.1 10.1 9.2 18.1 10.5 10.5 8.9 8.5 9.6 19.5 73.7 41.7 16.6 5.5 24.9 18.6 16.2 9.6 21.8 18.6 15.9 21.5 27.1 24.2 16.5 12.5 12.5 10.0 27.1 5.9 18.1 39.0 13.7 23.8 17.1 13.8 26.1 42.7 24.8 21.2 22.6 19.4 25.3 5.1 24.1 10.8 46.9 16.0 30.3 36.6 26.4 20.3 6.6 10.2 9.1 17.7 12.9 7.2 28.1 10.0 11.6 7.2 26.7 34.6 31.6 8.2 18.4 15.6 36.3 14.4 11.4 11.7 20.2 6.6 24.9 26.4 18.5 7.2 17.9 32.0 8.8 6.6 10.8 20.3 22.6 VMA21 "MEAX, XMEA" ENSG00000160131 "Vacuolar ATPase assembly factor VMA21" Q3ZAQ7 X 151396515-151409364 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010972 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010972: AB_1853034" "unprognostic (1.17e-1)" "prognostic favorable (2.30e-5)" "unprognostic (6.75e-2)" "unprognostic (9.78e-3)" "unprognostic (6.48e-2)" "unprognostic (4.68e-2)" "unprognostic (1.88e-3)" "unprognostic (4.36e-2)" "unprognostic (5.16e-2)" "unprognostic (1.74e-2)" "unprognostic (2.55e-1)" "unprognostic (8.30e-2)" "unprognostic (7.88e-2)" "unprognostic (4.17e-2)" "unprognostic (3.21e-2)" "unprognostic (3.90e-2)" "unprognostic (2.76e-1)" 10.4 12.2 16.5 7.6 17.0 22.8 10.6 16.2 17.1 9.6 18.3 6.8 6.3 9.0 14.1 9.3 13.6 6.6 7.5 18.5 23.5 12.8 9.8 8.0 11.4 19.8 20.8 10.5 8.7 11.6 10.9 12.0 20.3 8.6 6.6 15.6 8.1 8.2 7.9 12.5 6.6 7.8 20.1 9.9 7.0 8.3 18.3 10.3 13.3 7.1 12.4 8.5 7.6 19.6 21.5 23.5 26.7 28.3 25.9 24.7 26.2 23.7 25.4 21.4 21.1 17.8 27.5 63.1 75.3 24.2 24.0 19.1 37.5 22.6 33.2 22.2 18.6 27.5 25.9 32.3 34.6 52.4 30.4 25.8 27.4 24.3 34.1 22.8 24.9 27.2 14.9 32.2 40.6 20.4 35.8 51.9 33.3 25.7 24.5 35.9 31.8 40.6 25.5 17.3 9.6 20.3 18.4 24.3 29.0 24.4 14.9 34.1 25.4 34.6 15.6 44.3 38.5 27.1 50.8 91.7 35.2 63.9 35.4 11.9 12.4 7.7 6.5 14.4 8.5 7.7 8.5 8.3 13.6 6.0 11.3 10.5 2.8 12.8 13.1 12.2 9.4 10.6 16.5 17.0 16.2 17.1 18.5 23.5 19.8 20.8 20.3 20.1 18.3 19.6 38.5 22.4 24.4 9.1 46.5 44.9 28.0 35.3 42.7 40.2 35.8 31.1 46.8 30.0 21.0 31.3 18.8 33.2 62.9 21.0 19.6 28.2 50.6 44.1 22.4 34.6 22.1 52.5 16.4 33.0 66.7 28.0 15.8 24.1 24.1 25.7 32.2 38.9 143.7 20.2 19.1 22.5 20.3 150.3 86.6 51.5 18.3 89.8 39.2 5.6 142.9 49.9 53.5 13.0 14.3 47.7 17.6 22.6 50.9 43.8 26.8 33.5 28.6 26.2 52.6 31.7 34.5 27.4 58.8 46.0 51.6 31.9 41.6 37.0 21.8 30.5 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6 XKR8 FLJ10307 ENSG00000158156 "XK related 8" Q9H6D3 1 27959588-27968093 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "eosinophil: 202.8;neutrophil: 101.6" "Lineage enriched" "Detected in all" 13 "granulocytes: 202.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049984, HPA053529" Uncertain Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "HPA049984: AB_2680982, HPA053529: AB_2682179" "prognostic favorable (8.63e-4)" "unprognostic (2.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-3)" "unprognostic (1.97e-2)" "unprognostic (1.38e-2)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (7.87e-2)" "unprognostic (8.41e-2)" "unprognostic (1.83e-3)" "unprognostic (6.29e-2)" "unprognostic (8.55e-2)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-2)" 5.8 4.4 17.7 8.6 18.0 22.7 6.6 18.7 19.1 6.2 18.5 6.0 7.0 5.7 8.1 5.3 7.7 6.7 8.1 18.3 19.3 6.8 15.3 7.4 8.8 18.9 18.6 9.1 14.0 9.7 4.5 15.2 18.0 6.3 6.1 5.4 10.3 8.0 6.2 5.6 6.0 9.3 17.9 9.4 9.0 6.3 19.1 6.9 6.5 11.7 7.4 7.0 4.7 17.9 10.9 8.6 12.4 13.4 10.5 15.5 13.5 8.8 17.1 19.5 18.7 18.2 7.6 4.1 9.1 21.1 14.5 4.6 19.0 9.5 9.8 15.0 18.2 13.8 5.2 15.4 15.7 6.8 4.7 16.9 18.8 21.8 15.2 19.7 19.3 12.5 21.6 8.9 14.1 10.0 8.5 19.7 40.3 9.1 12.6 15.1 4.0 8.8 15.6 6.3 2.9 4.1 3.8 9.6 6.2 21.7 6.2 16.8 8.0 11.4 10.2 23.9 8.0 13.1 13.6 6.5 29.3 9.2 8.7 20.3 11.9 202.8 15.1 11.9 14.8 7.6 15.7 14.1 13.0 7.1 14.4 13.5 101.6 14.0 10.2 6.3 14.8 11.2 17.7 18.0 18.7 19.1 18.3 19.3 18.9 18.6 18.0 17.9 19.1 17.9 4.4 3.2 1.1 2.6 8.8 1.9 3.8 3.5 1.8 4.5 5.2 3.4 3.3 5.7 4.4 3.7 0.0 62.0 15.5 4.7 3.9 7.8 0.5 1.8 2.9 6.8 1.8 2.1 2.2 11.4 15.8 6.1 5.6 2.4 1.3 5.2 8.6 5.6 14.0 3.3 2.2 6.1 2.0 6.6 3.7 0.9 3.4 8.0 1.8 1.0 21.1 14.0 16.5 3.5 5.5 7.2 2.8 3.8 14.0 5.1 7.2 4.5 1.7 1.3 6.6 5.1 4.0 0.6 7.8 2.2 3.0 22.4 9.1 4.4 5.2 4.1 XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;testis: 7.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.0;Inhibitory neurons: 17.9;Oligodendrocytes: 23.0;Spermatocytes: 82.3;Spermatogonia: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;hTCEpi: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" 0.2 1.1 0.5 0.4 0.5 0.5 0.4 0.0 1.6 0.2 0.0 0.9 2.6 0.2 1.3 0.5 0.1 2.2 0.2 0.5 0.3 0.5 3.3 0.6 0.5 0.6 0.2 0.2 0.3 0.1 0.6 0.4 1.1 0.6 0.5 2.4 0.5 0.0 0.2 0.9 5.3 0.3 0.0 0.5 1.8 7.7 0.3 0.5 0.4 0.3 0.5 1.0 0.2 1.5 2.3 0.1 0.5 0.2 0.0 0.5 0.3 0.9 0.4 0.3 0.9 3.3 0.2 0.3 1.5 0.0 1.1 0.1 0.0 0.5 1.1 0.4 0.3 0.2 0.2 0.2 0.0 0.7 1.2 0.6 6.4 0.1 0.0 0.2 0.0 1.6 0.1 2.3 0.1 0.3 0.4 0.3 1.3 0.1 0.4 0.3 0.6 0.1 0.1 1.7 1.4 0.2 0.4 1.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 0.4 0.3 2.0 0.5 1.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.4 0.2 0.0 0.2 0.6 0.4 0.1 0.2 0.0 0.0 0.8 0.0 0.5 0.5 0.0 1.6 0.5 0.3 0.6 0.2 1.1 0.0 0.3 1.5 0.1 6.4 2.2 14.4 1.1 2.7 3.5 3.9 4.6 2.2 0.7 1.0 0.4 1.5 3.3 0.0 8.4 1.0 0.3 1.4 0.0 1.6 5.3 0.5 0.3 0.6 0.0 0.0 42.0 4.6 0.6 0.8 6.1 0.6 0.0 0.3 0.0 2.3 0.3 1.7 17.9 3.4 0.0 0.3 0.4 4.9 0.9 0.2 0.0 1.9 0.0 1.5 2.1 1.5 23.0 6.0 1.3 0.4 0.8 1.7 11.7 0.5 3.2 5.3 0.0 0.1 0.2 82.3 19.7 0.5 0.9 1.0 1.0 0.1 0.4 2.3 XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 4.3;Inhibitory neurons: 6.0;Microglial cells: 3.7;Oligodendrocytes: 5.5;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.35e-1)" "unprognostic (2.38e-2)" "unprognostic (4.51e-3)" "unprognostic (1.87e-1)" "unprognostic (8.53e-2)" "unprognostic (2.67e-2)" "unprognostic (2.96e-2)" "unprognostic (5.18e-2)" "unprognostic (3.69e-2)" "unprognostic (7.37e-2)" "unprognostic (5.70e-2)" "unprognostic (1.58e-2)" "unprognostic (5.60e-6)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.18e-1)" 0.0 0.6 0.5 0.8 0.3 0.1 0.6 0.1 0.3 0.7 0.0 0.7 0.3 0.2 1.1 2.3 0.6 0.1 0.0 0.2 1.7 0.1 0.0 1.2 1.6 0.3 0.4 0.2 0.0 0.0 1.0 0.3 0.3 0.3 0.8 0.2 0.5 0.9 0.1 9.7 2.4 0.1 0.2 0.5 0.3 0.2 1.2 1.8 0.4 0.0 3.5 0.3 1.7 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 8.2 1.0 0.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.4 0.1 0.0 0.3 1.6 0.0 0.0 0.0 1.6 0.1 1.3 0.2 0.7 0.1 0.7 0.0 0.1 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.9 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.1 0.3 0.2 1.7 0.3 0.4 0.3 0.2 1.2 0.2 0.0 0.0 0.0 9.4 0.7 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 1.8 3.7 0.1 0.2 0.0 1.0 5.5 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.9 2.6 0.2 0.0 0.2 0.4 YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014840: AB_2217189, HPA076194: " "unprognostic (9.35e-2)" "unprognostic (7.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (4.38e-3)" "unprognostic (2.25e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (6.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.03e-1)" "unprognostic (2.64e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (8.70e-4)" 49.2 54.7 33.4 28.4 36.0 16.7 47.5 38.5 41.4 42.7 42.4 50.8 56.5 53.5 34.5 50.9 45.7 25.5 57.8 33.5 35.6 50.9 149.5 44.9 22.9 38.9 36.1 42.1 86.0 40.6 74.1 34.5 38.2 47.3 37.7 12.3 51.1 29.6 96.2 43.0 47.4 41.1 38.5 35.9 56.1 36.4 35.6 21.6 49.9 59.3 24.7 45.4 40.6 41.9 80.7 131.3 39.4 72.6 130.0 138.7 73.8 114.4 122.3 95.5 94.3 126.0 95.5 67.9 111.5 161.4 107.8 119.9 60.7 107.9 75.6 77.7 72.0 42.5 93.3 158.7 147.4 59.3 61.5 97.4 144.4 98.6 158.9 76.6 91.3 67.0 80.7 114.8 84.3 199.3 71.3 64.4 40.3 147.4 136.6 54.9 61.2 203.9 81.9 70.9 58.5 57.9 62.5 106.7 103.4 49.6 155.5 43.5 81.0 80.8 69.0 165.3 54.1 78.1 86.0 63.0 125.4 56.2 90.2 19.4 95.6 20.6 71.3 141.4 78.4 95.9 60.6 67.2 116.4 82.4 48.0 55.3 9.4 51.2 140.0 141.6 54.9 99.8 33.4 36.0 38.5 41.4 33.5 35.6 38.9 36.1 38.2 38.5 35.6 41.9 63.4 38.5 48.0 6.2 52.2 36.1 88.1 170.4 38.1 27.1 84.4 92.7 34.5 82.9 115.5 46.0 22.9 114.3 42.6 66.8 64.6 137.9 28.1 42.1 84.8 53.6 87.4 21.0 1.9 149.4 248.5 90.4 55.0 42.8 29.9 38.8 49.2 172.0 105.4 26.9 3.9 140.9 116.0 38.4 44.9 48.6 75.5 45.0 72.9 8.4 40.8 73.7 28.8 10.1 10.4 132.1 93.3 82.4 92.4 195.2 202.2 135.2 101.4 34.0 39.5 60.8 150.0 61.0 56.8 63.3 46.3 154.3 36.5 88.1 107.2 112.1 YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Approved "Golgi apparatus,Vesicles" NA NA 37000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "Golgi apparatus" "HPA039328: AB_2676445, HPA055257: AB_2682762, HPA062675: AB_2684830" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.53e-5)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (5.53e-2)" "prognostic favorable (1.88e-4)" "unprognostic (4.57e-2)" "unprognostic (2.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (3.94e-3)" 30.1 30.7 29.3 33.0 32.4 69.1 26.7 37.0 38.3 33.5 29.0 26.6 20.4 24.1 10.9 33.2 25.6 16.5 40.6 30.2 32.6 27.2 58.3 35.7 32.1 36.3 30.9 26.7 27.1 16.9 29.1 23.5 38.6 23.7 16.1 13.6 30.2 12.5 35.0 26.0 24.0 18.1 33.4 47.7 22.0 23.1 34.0 20.9 19.8 26.7 20.9 26.8 25.6 38.5 43.7 108.9 48.3 57.5 68.4 63.5 37.8 103.2 79.0 75.7 110.7 53.5 32.6 75.7 44.4 121.1 81.5 27.4 85.9 54.6 28.7 81.1 43.3 117.0 48.2 56.5 94.8 82.4 132.9 52.3 47.9 78.0 33.8 76.1 71.3 99.4 152.9 205.3 68.5 46.0 87.6 98.9 37.0 74.9 33.7 89.0 58.6 117.9 48.9 40.6 34.8 58.1 34.5 76.7 55.4 37.2 29.9 163.2 68.8 74.6 73.2 108.4 83.9 76.4 122.1 51.8 96.1 150.5 54.6 81.9 155.7 179.0 60.8 119.4 54.4 49.3 57.3 54.8 300.3 42.7 46.7 47.5 42.8 44.0 70.8 127.0 59.0 120.2 29.3 32.4 37.0 38.3 30.2 32.6 36.3 30.9 38.6 33.4 34.0 38.5 27.4 0.0 5.5 5.5 22.8 17.7 19.4 25.8 18.2 12.2 22.6 18.7 4.7 18.6 14.2 22.0 12.5 44.7 17.0 16.0 0.0 39.4 6.3 17.5 18.2 23.9 14.4 33.2 7.3 27.7 52.9 23.8 16.3 18.6 22.9 43.4 37.1 30.5 94.4 11.8 7.4 24.7 32.6 42.3 37.4 8.5 9.0 53.3 35.6 3.7 34.4 20.8 16.5 4.0 12.7 15.5 13.5 9.1 69.4 14.8 8.1 16.1 20.7 15.5 6.6 11.1 40.3 20.6 31.9 30.7 20.0 27.6 18.8 26.2 25.9 19.5 YIPF3 "C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1" ENSG00000137207 "Yip1 domain family member 3" Q9GZM5 6 43511832-43516985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 494.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014859, HPA063699" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Nucleoplasm "HPA014859: AB_1845729, HPA063699: AB_2685095" "unprognostic (2.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (4.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.15e-3)" "unprognostic (3.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-2)" "unprognostic (3.55e-1)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" 72.3 120.2 78.9 43.3 79.9 46.4 70.0 79.5 92.0 74.0 102.6 74.3 65.2 72.1 100.5 80.3 69.7 63.3 87.6 80.2 78.9 78.2 105.4 68.9 42.6 80.5 79.2 75.6 152.0 110.0 91.9 77.8 81.2 76.3 62.1 49.8 118.6 61.1 82.8 70.0 66.1 57.5 78.3 67.2 106.1 48.0 81.6 46.0 74.3 83.4 46.5 69.1 67.3 80.8 95.0 66.2 95.3 185.4 208.3 168.5 56.1 111.9 174.6 91.8 115.7 79.1 67.6 37.8 84.4 208.6 78.4 93.4 71.0 110.2 59.4 69.9 95.7 61.2 91.8 153.2 163.2 64.7 85.9 169.0 141.2 77.9 78.3 154.4 141.1 61.1 67.8 88.2 111.5 146.9 47.5 82.3 49.7 494.4 71.1 42.6 43.0 103.2 164.3 101.4 76.7 109.0 50.3 66.9 122.2 72.8 111.4 133.5 133.5 103.1 53.4 57.0 78.8 102.5 88.8 74.3 73.2 53.5 71.5 147.2 84.8 128.7 60.0 82.2 52.3 46.1 53.7 54.1 78.7 48.5 42.7 48.5 316.0 65.5 83.2 70.3 79.8 78.2 78.9 79.9 79.5 92.0 80.2 78.9 80.5 79.2 81.2 78.3 81.6 80.8 77.8 35.3 33.6 12.7 41.4 40.7 63.8 121.7 63.2 54.6 62.8 49.4 31.7 82.9 86.5 55.2 37.5 192.2 41.1 109.7 49.0 149.6 38.1 63.5 60.5 78.9 107.1 42.1 12.1 101.8 209.5 78.2 59.7 67.9 40.6 77.9 74.6 71.0 99.3 58.9 14.7 117.6 101.7 49.1 31.2 79.0 69.9 49.6 65.8 14.0 72.4 115.0 42.2 15.1 17.7 117.5 108.8 67.0 111.6 71.4 129.1 74.9 51.2 63.5 32.9 45.5 64.4 44.0 40.8 52.8 35.5 264.1 34.9 101.9 80.0 81.6 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.7;Horizontal cells: 122.8;Inhibitory neurons: 108.1;Oligodendrocyte precursor cells: 315.2;Oligodendrocytes: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 4 "HDLM-2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 2.9 1.6 7.3 1.8 7.6 2.5 1.6 9.7 6.8 5.3 1.1 2.4 2.8 12.4 0.4 1.7 2.0 2.3 5.2 7.5 5.1 4.6 4.4 3.0 2.4 12.5 9.1 1.4 2.5 5.6 1.6 2.2 10.9 3.5 1.7 1.3 2.1 1.4 2.3 1.4 4.1 6.1 13.5 3.1 3.8 3.3 10.8 0.9 1.7 3.9 2.4 2.4 1.9 22.7 2.6 2.7 0.8 3.8 2.0 1.5 8.7 4.1 3.7 2.8 2.5 3.3 1.9 6.4 1.4 3.3 5.4 1.3 2.2 2.2 2.5 50.9 3.2 12.7 1.0 1.5 2.7 1.7 2.8 1.1 2.3 2.9 1.2 2.4 4.3 2.8 10.4 4.7 1.6 1.7 1.1 4.2 1.6 5.1 3.2 0.2 0.4 3.9 5.8 1.1 6.3 1.9 4.8 3.1 3.5 1.6 0.4 2.0 6.0 4.2 3.1 8.3 5.2 1.1 1.3 0.9 1.5 4.5 4.7 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 7.3 7.6 9.7 6.8 7.5 5.1 12.5 9.1 10.9 13.5 10.8 22.7 23.4 3.2 0.0 45.4 9.8 12.9 2.1 3.0 4.0 25.3 5.8 8.0 18.3 12.8 1.4 7.3 6.2 12.5 11.2 7.4 11.7 7.5 10.7 5.0 16.6 15.1 2.4 4.2 161.7 3.1 2.2 11.4 6.1 9.4 0.0 7.7 22.5 23.1 11.4 122.8 108.1 9.8 6.1 15.5 6.7 5.9 8.1 8.8 10.6 65.6 3.8 5.4 7.2 315.2 221.0 2.7 8.5 10.1 4.5 14.2 6.0 3.8 0.4 6.0 0.0 6.2 8.4 7.2 10.0 1.5 8.4 21.1 6.6 4.6 11.5 2.7 ZDHHC16 APH2 ENSG00000171307 "Zinc finger DHHC-type palmitoyltransferase 16" Q969W1 10 97446170-97457370 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, DNA damage" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039893, HPA040214" Uncertain Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane, Cytosol" "HPA039893: AB_10794757, HPA040214: AB_2676886" "unprognostic (4.44e-2)" "unprognostic (3.14e-2)" "unprognostic (3.34e-1)" "unprognostic (1.20e-2)" "unprognostic (8.75e-2)" "unprognostic (8.35e-3)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (5.49e-2)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (6.34e-2)" "unprognostic (1.93e-3)" "unprognostic (1.34e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-1)" 15.6 14.9 17.8 10.2 18.5 6.8 16.3 20.3 21.9 15.0 16.4 17.1 14.3 16.4 18.5 19.9 12.2 9.9 22.1 18.1 16.5 25.1 30.3 20.8 11.3 17.2 17.8 15.9 22.8 25.5 16.7 21.6 16.4 18.3 17.3 17.4 24.2 12.1 25.8 13.1 14.7 16.6 16.1 14.5 24.1 17.3 18.8 12.6 16.0 27.9 15.1 17.1 15.3 16.7 50.7 57.4 37.9 47.1 58.7 40.4 38.7 54.6 72.1 61.2 58.4 45.7 43.6 44.4 60.1 79.8 53.4 58.0 48.2 76.7 54.2 43.7 56.0 28.5 39.8 44.3 47.4 34.0 39.7 45.7 49.8 71.6 51.3 66.3 63.9 40.4 23.1 32.8 79.0 48.4 51.8 46.0 29.9 45.8 49.5 34.0 38.6 40.9 51.9 23.2 18.4 25.9 33.2 33.7 30.6 37.7 44.6 32.9 39.6 38.2 35.0 25.0 64.7 29.2 53.0 26.9 44.1 51.7 20.7 0.3 11.1 11.1 7.2 11.9 8.1 9.0 12.5 11.5 15.7 10.6 10.0 10.1 0.5 14.5 11.8 12.0 11.1 6.8 17.8 18.5 20.3 21.9 18.1 16.5 17.2 17.8 16.4 16.1 18.8 16.7 6.2 19.2 23.1 3.9 9.0 5.2 18.9 31.8 14.8 15.8 13.6 9.3 10.1 14.3 27.6 12.9 4.2 39.8 10.3 11.5 25.4 35.5 24.8 7.0 13.3 11.3 7.2 11.6 8.2 32.3 67.2 13.7 10.2 10.9 7.0 13.3 7.5 19.5 24.6 13.5 9.2 18.9 28.5 7.3 5.9 7.6 8.7 9.3 3.6 9.4 18.4 14.9 15.5 11.1 8.4 31.5 12.1 3.8 17.1 20.0 18.9 22.2 8.3 13.0 6.6 5.2 12.2 20.1 12.9 13.8 4.3 37.9 7.2 10.9 20.9 19.3 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Cell line enhanced" "Detected in all" "HDLM-2: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 23.4 8.1 26.0 27.4 24.6 113.9 17.0 25.7 29.0 12.9 16.9 14.6 12.9 13.6 4.6 24.3 11.3 14.8 15.0 25.4 30.0 8.8 18.6 16.2 22.1 29.1 28.7 9.6 10.5 8.6 11.7 23.3 33.5 11.4 15.0 19.3 16.9 9.1 10.8 18.5 13.9 18.4 22.2 31.3 12.4 7.4 28.5 14.7 15.3 16.1 20.9 22.7 14.4 25.1 45.3 19.8 31.5 21.8 25.6 17.8 30.9 26.7 31.5 45.9 33.9 18.3 28.4 20.9 16.7 35.5 24.0 31.3 33.8 15.9 39.2 132.6 28.7 20.3 15.3 25.7 22.0 18.1 16.9 15.5 21.3 42.3 27.9 16.5 25.9 31.6 21.4 41.8 18.4 22.1 34.5 14.6 30.4 28.1 18.8 28.3 27.2 22.2 19.2 11.3 14.6 17.7 17.9 13.4 19.3 23.9 12.1 17.6 22.2 31.5 24.2 52.3 31.0 49.7 38.8 18.1 17.9 32.5 21.9 0.0 0.5 10.0 1.6 1.1 1.1 0.4 1.2 1.2 0.8 0.3 0.7 0.8 48.8 1.0 0.8 0.4 2.7 0.5 26.0 24.6 25.7 29.0 25.4 30.0 29.1 28.7 33.5 22.2 28.5 25.1 12.9 9.6 7.9 6.5 7.5 25.6 8.6 4.4 6.8 39.8 8.4 6.6 6.0 10.0 6.8 1.8 27.1 10.6 21.2 27.0 0.0 4.1 3.8 6.1 7.0 9.1 3.0 9.3 10.2 2.8 7.1 7.1 4.6 12.7 1.3 5.9 7.9 12.0 7.3 18.5 10.2 3.9 2.0 8.5 17.0 2.1 6.2 11.0 10.6 5.6 26.6 5.7 12.3 4.0 6.3 8.0 25.6 3.8 8.3 19.3 10.4 2.2 4.6 35.3 0.0 7.1 6.2 3.5 11.4 14.6 36.2 6.2 17.4 8.0 7.0 34.7 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZDHHC23 MGC42530 ENSG00000184307 "Zinc finger DHHC-type palmitoyltransferase 23" Q8IYP9 3 113947901-113965401 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 26.7;Excitatory neurons: 72.2;Late spermatids: 41.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 9 "amygdala: 5.4;basal ganglia: 7.3;cerebral cortex: 9.4;hippocampal formation: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016808 Uncertain Approved Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA016808: AB_1859002" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (4.48e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.49e-1)" "unprognostic (3.98e-3)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (3.19e-1)" "unprognostic (6.63e-2)" "unprognostic (1.86e-1)" "unprognostic (2.78e-2)" "prognostic favorable (1.48e-7)" "unprognostic (2.58e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (5.90e-4)" "unprognostic (3.29e-3)" 1.1 1.0 5.4 3.0 7.3 1.2 2.6 0.0 9.4 1.4 13.2 9.4 7.3 1.2 1.5 1.5 2.4 1.6 1.0 7.4 0.0 5.5 4.0 3.2 2.8 0.0 0.0 0.9 4.8 7.4 3.2 0.9 0.0 2.5 11.5 3.6 6.6 1.8 1.2 3.8 6.8 1.3 0.0 2.4 6.2 12.2 0.0 1.2 6.1 0.9 3.8 1.9 1.5 0.8 17.8 4.4 0.5 10.1 1.5 0.3 14.8 6.9 2.1 1.3 2.0 7.1 11.6 8.1 5.9 4.0 11.0 11.4 13.0 1.9 2.2 4.9 6.0 7.5 7.0 4.4 0.5 8.5 6.7 0.3 2.2 0.3 0.8 1.6 1.1 8.5 0.0 4.6 0.2 10.2 7.0 0.5 3.1 18.2 4.9 1.2 5.8 6.8 7.0 8.6 17.6 4.4 5.3 17.5 3.3 3.9 10.5 2.7 0.3 4.8 9.6 1.0 3.1 5.2 7.3 13.2 4.1 5.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 5.4 7.3 0.0 9.4 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.3 0.0 1.5 12.1 10.5 3.1 2.0 2.3 0.6 2.1 4.8 4.2 1.4 7.2 2.2 16.5 8.4 0.9 2.7 21.8 0.0 2.1 26.7 13.6 1.6 2.8 13.8 0.4 72.2 1.9 1.6 1.0 9.2 8.5 0.0 3.2 4.2 6.4 0.4 0.0 4.0 12.7 0.0 0.3 2.2 41.0 1.2 1.3 3.6 2.8 1.0 4.2 0.0 2.5 5.4 0.7 8.3 0.0 2.3 3.9 10.9 4.4 8.7 0.9 0.0 1.7 0.7 18.2 2.9 2.1 2.7 0.3 1.3 0.9 12.6 1.7 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 570.7;Late spermatids: 1564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 50.1 48.6 23.0 25.7 21.5 82.8 36.3 27.9 22.9 42.2 25.8 70.6 44.1 35.4 24.5 58.0 27.5 32.0 36.3 25.8 21.1 40.3 32.3 41.9 21.9 28.7 25.1 28.9 22.2 46.0 13.4 28.7 29.8 35.6 64.6 16.6 33.3 40.1 43.7 70.0 58.1 36.3 25.8 29.6 55.3 80.8 27.0 26.9 38.6 52.8 33.3 53.6 42.5 25.3 62.5 53.3 41.0 49.1 219.2 100.5 46.8 58.8 80.7 78.3 66.5 61.0 85.1 58.7 31.4 107.9 52.8 80.7 68.4 104.3 74.6 61.7 29.3 55.9 57.9 45.7 50.6 136.3 43.0 92.5 111.6 73.6 67.2 59.8 79.6 63.8 73.8 51.3 78.1 42.9 46.2 73.6 60.7 155.9 96.7 29.9 40.6 47.0 66.7 176.7 14.6 52.8 70.3 70.5 36.4 70.4 57.4 88.2 78.0 55.4 55.2 60.2 66.3 32.2 66.6 59.6 55.2 198.9 39.4 53.7 24.5 32.6 14.6 12.3 13.3 10.7 11.0 16.1 26.8 12.6 10.2 14.4 25.4 14.5 17.5 15.3 17.1 13.6 23.0 21.5 27.9 22.9 25.8 21.1 28.7 25.1 29.8 25.8 27.0 25.3 41.5 41.7 82.1 7.5 17.8 48.2 42.1 40.8 48.9 9.8 24.4 20.8 29.2 24.3 27.1 53.3 6.2 47.7 23.4 105.6 72.4 46.6 570.7 18.8 31.2 34.1 35.9 68.8 15.7 79.0 59.4 26.4 69.3 26.6 19.0 21.5 35.7 29.4 49.5 15.2 15.6 78.2 38.7 34.0 26.7 1564.3 51.9 37.4 24.9 18.7 35.6 25.1 34.0 15.1 11.2 115.8 73.1 44.8 26.2 73.7 112.9 30.1 20.9 10.6 19.7 15.6 31.9 104.5 45.3 70.5 60.2 101.7 25.0 26.1 72.8 128.9 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "HPA019215: AB_2670102, HPA059054: AB_2683892, HPA059642: AB_2684093" "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" 33.0 28.1 19.0 24.7 18.8 64.2 26.8 21.4 18.6 40.0 27.1 42.5 27.1 36.8 12.8 27.6 27.7 31.2 31.2 19.1 19.8 35.4 30.0 37.2 26.5 20.1 21.0 27.7 26.9 35.5 19.6 33.4 20.3 32.8 32.4 10.3 24.1 20.0 56.5 31.8 33.5 30.0 19.1 35.4 44.7 14.1 23.5 16.1 25.5 58.4 23.5 37.4 33.1 19.6 63.8 55.0 28.5 34.5 123.1 92.3 38.9 57.4 110.8 88.4 43.7 58.3 72.4 29.1 32.7 93.5 29.0 65.6 37.1 76.1 110.9 16.4 29.7 21.0 22.0 66.5 51.5 40.0 21.2 76.7 85.4 72.5 41.5 56.0 46.1 26.7 68.9 9.7 56.8 75.8 27.0 38.1 44.3 53.2 39.5 33.6 26.2 15.7 86.4 82.5 24.2 29.8 74.3 40.9 36.1 43.0 77.6 24.0 67.9 53.1 39.9 49.8 34.3 33.5 51.0 65.5 50.1 29.1 43.0 7.5 9.7 8.3 2.1 8.2 2.6 1.4 2.0 1.7 6.3 2.2 1.5 2.2 6.4 1.4 7.2 4.3 0.5 3.6 19.0 18.8 21.4 18.6 19.1 19.8 20.1 21.0 20.3 19.1 23.5 19.6 13.3 32.1 25.2 12.1 10.8 13.3 21.5 25.4 17.1 9.2 16.2 13.2 22.5 12.8 17.9 16.5 6.2 18.5 15.7 37.7 1.9 14.1 9.7 15.5 20.1 12.2 12.6 11.6 16.4 15.6 24.9 23.0 28.5 29.1 3.8 14.3 15.0 11.6 28.1 15.2 16.2 29.4 14.2 46.8 26.7 10.9 17.4 36.2 16.0 19.7 42.9 5.9 21.6 13.6 14.7 30.0 33.9 21.1 15.2 26.2 22.1 9.5 32.6 6.7 13.1 13.7 14.9 8.3 13.0 20.1 12.8 16.1 13.4 6.8 34.7 35.3 ZDHHC8 "KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" 31.6 31.2 13.8 18.6 15.1 10.7 30.4 11.3 26.4 32.6 0.0 22.8 12.1 31.2 7.5 29.3 27.7 13.0 31.6 13.9 7.0 30.4 36.1 31.0 17.1 12.2 10.0 34.6 35.6 14.4 41.3 16.9 9.9 28.1 7.0 7.4 27.6 15.4 23.6 32.2 24.7 13.1 6.6 35.7 26.4 14.9 12.3 13.7 37.3 10.3 11.7 25.3 30.9 12.8 30.0 18.7 29.3 38.7 42.0 25.0 26.3 55.1 37.3 36.6 32.6 9.8 15.2 0.1 22.3 46.0 19.8 40.2 15.5 42.2 18.0 43.2 59.4 14.5 57.2 23.0 34.5 0.0 19.5 43.7 27.9 28.2 23.6 22.5 41.4 21.0 101.4 22.8 33.0 14.7 17.8 39.1 14.9 13.2 29.4 37.8 25.6 10.9 15.6 35.9 46.9 23.7 22.4 10.7 26.6 13.1 0.7 20.4 48.0 82.5 59.8 46.8 25.0 32.6 11.5 11.7 24.2 18.7 24.8 1.3 0.4 0.1 0.8 0.5 0.4 0.2 0.2 0.4 0.1 0.5 0.4 0.5 0.0 0.4 0.2 1.3 0.7 0.2 13.8 15.1 11.3 26.4 13.9 7.0 12.2 10.0 9.9 6.6 12.3 12.8 17.4 3.2 3.1 17.6 3.7 9.1 3.8 3.6 5.7 11.9 8.2 8.1 7.1 4.3 3.5 11.0 14.6 3.6 9.2 4.3 1.9 5.2 0.5 4.3 15.7 11.5 4.2 0.8 16.6 4.5 8.5 9.3 10.2 8.7 5.7 8.7 10.4 9.8 4.9 13.5 9.9 5.9 10.2 5.0 5.0 2.1 10.8 5.7 5.4 9.4 3.7 7.4 1.0 13.0 13.3 7.7 5.4 14.7 2.7 7.6 2.7 2.1 1.5 10.8 6.6 10.5 6.8 1.4 3.8 5.5 9.8 3.4 4.2 8.0 5.0 3.4 ZDHHC9 "CGI-89, CXorf11, DHHC9, ZDHHC10, ZNF379, ZNF380" ENSG00000188706 "Zinc finger DHHC-type palmitoyltransferase 9" Q9Y397 X 129803288-129843909 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.0;Oligodendrocytes: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031814 Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA031814: AB_10610700" "prognostic unfavorable (9.77e-5)" "prognostic unfavorable (4.64e-5)" "unprognostic (2.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.01e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-1)" "unprognostic (3.49e-2)" "unprognostic (9.70e-3)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.17e-2)" "unprognostic (4.11e-2)" 28.2 12.0 39.2 10.2 66.6 5.4 24.3 46.5 52.5 19.1 23.3 22.0 31.6 11.8 11.7 15.6 12.1 15.3 15.5 39.2 49.0 37.1 40.1 26.7 3.3 60.5 58.2 11.2 25.9 25.2 11.4 17.2 52.5 18.8 24.9 6.0 21.1 11.3 13.4 35.3 34.0 15.3 44.8 3.9 19.5 4.1 57.8 3.6 13.8 11.3 6.6 23.8 14.5 78.6 45.9 23.8 33.2 67.5 112.4 87.7 27.0 44.3 50.6 20.9 26.0 37.6 58.4 1.6 73.7 47.6 54.0 30.4 38.0 44.6 30.0 2.6 23.7 9.2 24.0 50.1 44.4 6.1 15.7 96.0 71.1 34.0 50.1 36.5 39.9 15.0 10.1 17.6 34.0 40.0 8.8 11.4 18.0 102.3 40.4 8.2 21.4 27.1 30.1 25.2 26.3 22.0 12.7 64.7 20.5 38.9 27.6 10.1 32.8 21.1 7.3 50.0 36.3 16.5 12.7 5.5 37.9 25.1 10.8 0.0 2.2 1.8 3.0 2.0 3.7 2.7 3.6 2.9 2.4 1.5 4.5 2.6 0.0 2.5 5.2 5.1 1.8 2.1 39.2 66.6 46.5 52.5 39.2 49.0 60.5 58.2 52.5 44.8 57.8 78.6 66.0 22.4 28.6 4.6 2.8 18.6 12.4 12.8 13.1 9.1 16.8 15.1 4.6 17.2 15.9 46.0 2.1 5.6 2.7 20.1 3.9 18.6 1.8 23.8 16.9 16.6 18.0 4.2 10.5 19.8 19.1 32.7 18.3 59.7 2.5 11.5 7.9 43.7 4.9 1.7 11.8 23.2 10.2 3.5 12.2 2.0 12.2 3.9 10.6 7.5 0.3 1.5 1.0 9.5 118.2 33.5 14.6 7.5 7.7 39.1 51.0 25.8 7.2 2.8 0.0 9.5 11.1 8.4 8.7 16.9 19.2 10.3 5.1 7.5 27.2 22.1 ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" Cytosol "HPA037523: AB_10672351, HPA069876: AB_2686218" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-2)" "unprognostic (7.15e-2)" "unprognostic (2.05e-3)" "unprognostic (5.24e-2)" "unprognostic (3.38e-3)" "prognostic favorable (7.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.26e-2)" "prognostic favorable (7.80e-4)" 14.4 27.9 33.1 12.9 32.1 23.2 15.8 29.2 35.9 20.6 34.8 25.6 24.8 16.5 22.9 16.5 20.3 12.1 17.8 35.5 33.6 28.3 32.6 17.7 16.1 32.6 31.4 25.9 23.7 19.2 38.3 9.5 33.2 22.0 16.3 28.4 18.9 10.3 12.8 18.2 30.6 8.5 29.1 29.1 19.8 23.0 33.5 12.7 20.4 5.9 13.1 16.8 17.0 32.4 17.7 21.4 12.6 28.1 14.1 9.8 17.2 17.7 18.5 20.3 19.7 19.1 35.9 27.2 19.8 12.8 25.9 38.8 18.4 17.2 10.6 28.3 18.6 12.9 23.1 18.1 18.1 20.9 24.9 16.0 20.4 19.9 15.2 32.4 11.5 22.5 19.6 17.9 15.3 13.8 16.9 39.4 10.3 15.3 16.4 19.2 12.7 13.0 19.5 10.8 10.1 19.7 11.9 9.9 47.2 11.5 21.8 20.5 12.4 10.2 11.9 15.6 34.2 20.6 18.6 14.3 25.3 26.5 11.9 4.8 5.8 9.3 9.6 6.2 8.2 7.1 6.6 7.9 5.4 6.7 7.5 8.3 8.2 6.8 9.2 5.6 9.5 8.3 33.1 32.1 29.2 35.9 35.5 33.6 32.6 31.4 33.2 29.1 33.5 32.4 10.0 3.2 11.4 14.0 22.1 8.2 12.8 11.3 18.8 29.9 11.1 8.9 7.2 14.3 9.7 14.7 58.4 7.4 21.2 33.9 7.9 14.9 5.2 14.3 7.8 11.0 20.3 14.3 33.6 16.0 5.7 10.1 19.4 11.4 14.0 17.3 10.8 10.9 8.2 37.0 35.2 15.6 14.2 8.8 5.7 1.5 9.6 11.0 10.6 16.9 11.2 14.8 15.5 12.5 20.2 13.9 26.1 9.1 13.4 13.8 35.5 8.6 16.6 43.7 19.7 6.7 9.9 8.9 7.6 10.4 5.5 13.5 17.9 10.9 14.7 17.7 ZNRF4 "RNF204, spzn, Ssrzf1" ENSG00000105428 "Zinc and ring finger 4" Q8WWF5 19 5455417-5456856 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 905 "testis: 120.1" "Group enriched" "Detected in some" 62 "Early spermatids: 636.6;Late spermatids: 593.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 636.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 593.9 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Mitochondria "HPA031778: AB_10599831, HPA031790: AB_10600999" "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (6.75e-2)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.80e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "prognostic favorable (6.08e-4)" "unprognostic (1.54e-1)" "unprognostic (1.38e-3)" "unprognostic (6.09e-3)" "unprognostic (1.80e-1)" "unprognostic (9.43e-2)" "unprognostic (6.46e-2)" 10.2 10.6 6.4 10.1 6.7 20.8 9.7 7.4 7.3 8.4 18.3 19.2 15.5 9.9 5.7 11.1 9.1 6.4 11.0 7.1 6.0 7.6 9.0 11.3 10.1 8.0 6.9 10.1 14.2 12.1 11.2 6.0 7.8 10.1 14.6 11.2 9.1 7.4 22.2 12.1 27.5 8.8 5.8 14.2 12.0 8.0 8.5 15.1 10.7 13.3 9.7 10.9 8.1 7.5 13.1 20.1 7.1 9.7 17.4 9.8 8.5 11.1 13.9 12.7 12.3 10.0 4.5 12.4 7.3 15.0 8.4 14.6 14.4 7.6 12.9 14.5 15.0 12.0 16.4 6.5 11.8 10.2 22.6 12.6 10.0 12.5 14.7 6.6 16.6 12.3 8.8 12.2 8.0 8.9 12.7 6.0 4.3 12.5 7.6 14.0 8.6 5.4 7.1 13.2 5.6 8.2 12.6 7.7 10.8 7.0 7.6 7.7 19.7 11.1 5.6 14.1 14.7 5.4 3.0 6.3 11.1 8.9 10.5 0.7 0.6 0.6 0.8 0.9 1.0 0.4 0.5 0.5 0.5 0.3 0.3 0.6 1.0 0.2 1.0 0.4 0.4 0.4 6.4 6.7 7.4 7.3 7.1 6.0 8.0 6.9 7.8 5.8 8.5 7.5 19.3 57.7 54.8 39.8 23.5 7.1 5.4 6.6 13.1 30.6 12.6 10.3 22.8 18.6 30.0 9.2 98.0 8.3 23.7 93.4 0.0 7.3 48.9 18.8 17.4 19.2 13.2 12.4 50.3 11.2 6.4 21.6 46.4 25.6 26.5 21.8 23.2 15.2 11.9 40.4 55.3 38.5 12.2 30.5 10.6 26.8 14.9 29.0 12.4 22.5 20.4 15.8 19.6 35.2 53.6 14.9 34.3 9.8 27.8 9.5 115.2 4.8 22.7 50.3 6.6 23.7 15.2 12.0 11.8 16.4 10.1 8.9 31.1 18.0 28.6 9.3