[{"Gene":"BACE1","Gene synonym":["BACE"],"Ensembl":"ENSG00000186318","Gene description":"Beta-secretase 1","Uniprot":["P56817"],"Chromosome":"11","Position":"117285207-117316259","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"119.1","pancreas":"271.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"118.9","Early spermatids":"99.9","Late spermatids":"343.0","Oligodendrocytes":"99.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"88.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016358"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB016358":"AB_626716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.76e-4"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"16.0","Tissue RNA - amygdala [nTPM]":"34.3","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"68.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"68.7","Tissue RNA - cerebral cortex [nTPM]":"44.0","Tissue RNA - cervix [nTPM]":"18.3","Tissue RNA - choroid plexus [nTPM]":"11.9","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"19.7","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"15.9","Tissue RNA - gallbladder [nTPM]":"19.1","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"34.3","Tissue RNA - hypothalamus [nTPM]":"44.5","Tissue RNA - kidney [nTPM]":"14.8","Tissue RNA - liver [nTPM]":"25.6","Tissue RNA - lung [nTPM]":"14.4","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"89.7","Tissue RNA - midbrain [nTPM]":"67.0","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"271.5","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"10.7","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"76.6","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"44.7","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"18.3","Tissue RNA - skeletal muscle [nTPM]":"12.5","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"21.3","Tissue RNA - spinal cord [nTPM]":"61.6","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"11.2","Tissue RNA - thalamus [nTPM]":"59.9","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"12.4","Tissue RNA - vagina [nTPM]":"14.3","Tissue RNA - white matter [nTPM]":"119.1","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"10.7","Cell RNA - AF22 [nTPM]":"22.9","Cell RNA - AN3-CA [nTPM]":"37.3","Cell RNA - ASC diff [nTPM]":"80.9","Cell RNA - ASC TERT1 [nTPM]":"82.3","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.0","Cell RNA - CACO-2 [nTPM]":"4.5","Cell RNA - CAPAN-2 [nTPM]":"16.4","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"88.3","Cell RNA - GAMG [nTPM]":"18.4","Cell RNA - HaCaT [nTPM]":"17.9","Cell RNA - HAP1 [nTPM]":"24.3","Cell RNA - HBEC3-KT [nTPM]":"12.1","Cell RNA - HBF TERT88 [nTPM]":"20.5","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"12.1","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"36.5","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"1.7","Cell RNA - HSkMC [nTPM]":"68.1","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.7","Cell RNA - hTERT-HME1 [nTPM]":"31.8","Cell RNA - hTERT-RPE1 [nTPM]":"68.0","Cell RNA - HUVEC TERT2 [nTPM]":"21.4","Cell RNA - JURKAT [nTPM]":"3.8","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"46.5","Cell RNA - MCF7 [nTPM]":"33.4","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"15.5","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"25.9","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"11.6","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"31.7","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"22.5","Cell RNA - SK-BR-3 [nTPM]":"2.6","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"26.2","Cell RNA - THP-1 [nTPM]":"7.6","Cell RNA - TIME [nTPM]":"31.4","Cell RNA - U-138 MG [nTPM]":"45.2","Cell RNA - U-2 OS [nTPM]":"5.0","Cell RNA - U-2197 [nTPM]":"48.2","Cell RNA - U-251 MG [nTPM]":"19.4","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"23.8","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"34.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"34.3","Brain RNA - basal ganglia [nTPM]":"68.5","Brain RNA - cerebellum [nTPM]":"68.7","Brain RNA - cerebral cortex [nTPM]":"44.0","Brain RNA - hippocampal formation [nTPM]":"34.3","Brain RNA - hypothalamus [nTPM]":"44.5","Brain RNA - medulla oblongata [nTPM]":"89.7","Brain RNA - midbrain [nTPM]":"67.0","Brain RNA - pons [nTPM]":"76.6","Brain RNA - spinal cord [nTPM]":"61.6","Brain RNA - thalamus [nTPM]":"59.9","Brain RNA - white matter [nTPM]":"119.1","Single Cell Type RNA - Adipocytes [nTPM]":"12.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"53.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"13.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"118.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"99.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"15.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"38.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.7","Single Cell Type RNA - Late spermatids [nTPM]":"343.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"17.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"55.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"68.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"BACE2","Gene synonym":["AEPLC","ALP56","CEAP1","DRAP"],"Ensembl":"ENSG00000182240","Gene description":"Beta-secretase 2","Uniprot":["Q9Y5Z0"],"Chromosome":"21","Position":"41167801-41282530","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"26.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"290.4","Syncytiotrophoblasts":"514.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"2.9","eosinophil":"5.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"5.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"73.8","SK-BR-3":"53.3","SK-MEL-30":"52.6","WM-115":"46.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035416"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035416":"AB_2732467"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"8.7","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"6.3","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"6.7","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"13.1","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"26.8","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"2.2","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"4.5","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"4.7","Tissue RNA - stomach 1 [nTPM]":"22.9","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"27.4","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"12.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"9.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"7.1","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"8.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"13.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"12.6","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"5.5","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"2.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"73.8","Cell RNA - PC-3 [nTPM]":"12.1","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"53.3","Cell RNA - SK-MEL-30 [nTPM]":"52.6","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"15.8","Cell RNA - U-138 MG [nTPM]":"7.3","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"17.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"46.2","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"6.7","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.8","Single Cell Type RNA - B-cells [nTPM]":"28.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"91.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"123.0","Single Cell Type RNA - Club cells [nTPM]":"72.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"127.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"93.9","Single Cell Type RNA - Ductal cells [nTPM]":"146.3","Single Cell Type RNA - Early spermatids [nTPM]":"24.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"65.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.8","Single Cell Type RNA - Endothelial cells [nTPM]":"90.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.5","Single Cell Type RNA - Erythroid cells [nTPM]":"22.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"105.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"64.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"186.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"115.8","Single Cell Type RNA - granulocytes [nTPM]":"90.7","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"86.2","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"17.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"16.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"3.6","Single Cell Type RNA - Melanocytes [nTPM]":"179.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"2.9","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"86.6","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"290.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"76.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"514.7","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.6","Single Cell Type RNA - Urothelial cells [nTPM]":"134.2"},{"Gene":"CTSD","Gene synonym":["CLN10","CPSD"],"Ensembl":"ENSG00000117984","Gene description":"Cathepsin D","Uniprot":["P07339"],"Chromosome":"11","Position":"1752752-1764573","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Cancer-related genes","Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1475.9","Hofbauer cells":"3763.5","Macrophages":"1512.6","Proximal enterocytes":"1699.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"2596.6","hTERT-RPE1":"2780.1","SK-BR-3":"2488.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000109","HPA003001"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000109":null,"HPA003001":"AB_1078404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"318.6","Tissue RNA - adrenal gland [nTPM]":"734.6","Tissue RNA - amygdala [nTPM]":"147.0","Tissue RNA - appendix [nTPM]":"204.9","Tissue RNA - basal ganglia [nTPM]":"181.9","Tissue RNA - bone marrow [nTPM]":"499.0","Tissue RNA - breast [nTPM]":"244.0","Tissue RNA - cerebellum [nTPM]":"186.0","Tissue RNA - cerebral cortex [nTPM]":"156.5","Tissue RNA - cervix [nTPM]":"270.8","Tissue RNA - choroid plexus [nTPM]":"672.7","Tissue RNA - colon [nTPM]":"298.0","Tissue RNA - duodenum [nTPM]":"387.6","Tissue RNA - endometrium 1 [nTPM]":"170.7","Tissue RNA - epididymis [nTPM]":"82.8","Tissue RNA - esophagus [nTPM]":"319.4","Tissue RNA - fallopian tube [nTPM]":"171.6","Tissue RNA - gallbladder [nTPM]":"438.4","Tissue RNA - heart muscle [nTPM]":"444.1","Tissue RNA - hippocampal formation [nTPM]":"187.8","Tissue RNA - hypothalamus [nTPM]":"223.6","Tissue RNA - kidney [nTPM]":"691.6","Tissue RNA - liver [nTPM]":"464.8","Tissue RNA - lung [nTPM]":"539.6","Tissue RNA - lymph node [nTPM]":"241.0","Tissue RNA - medulla oblongata [nTPM]":"247.6","Tissue RNA - midbrain [nTPM]":"206.6","Tissue RNA - ovary [nTPM]":"130.7","Tissue RNA - pancreas [nTPM]":"284.8","Tissue RNA - parathyroid gland [nTPM]":"137.3","Tissue RNA - pituitary gland [nTPM]":"131.5","Tissue RNA - placenta [nTPM]":"180.7","Tissue RNA - pons [nTPM]":"228.6","Tissue RNA - prostate [nTPM]":"138.2","Tissue RNA - rectum [nTPM]":"153.4","Tissue RNA - retina [nTPM]":"48.3","Tissue RNA - salivary gland [nTPM]":"422.1","Tissue RNA - seminal vesicle [nTPM]":"231.7","Tissue RNA - skeletal muscle [nTPM]":"590.3","Tissue RNA - skin 1 [nTPM]":"340.9","Tissue RNA - small intestine [nTPM]":"398.3","Tissue RNA - smooth muscle [nTPM]":"105.0","Tissue RNA - spinal cord [nTPM]":"188.9","Tissue RNA - spleen [nTPM]":"442.0","Tissue RNA - stomach 1 [nTPM]":"287.2","Tissue RNA - testis [nTPM]":"88.9","Tissue RNA - thalamus [nTPM]":"334.4","Tissue RNA - thymus [nTPM]":"78.1","Tissue RNA - thyroid gland [nTPM]":"182.1","Tissue RNA - tongue [nTPM]":"178.2","Tissue RNA - tonsil [nTPM]":"123.1","Tissue RNA - urinary bladder [nTPM]":"296.4","Tissue RNA - vagina [nTPM]":"307.5","Tissue RNA - white matter [nTPM]":"367.1","Cell RNA - A-431 [nTPM]":"204.6","Cell RNA - A549 [nTPM]":"578.9","Cell RNA - AF22 [nTPM]":"51.4","Cell RNA - AN3-CA [nTPM]":"246.2","Cell RNA - ASC diff [nTPM]":"586.5","Cell RNA - ASC TERT1 [nTPM]":"206.3","Cell RNA - BEWO [nTPM]":"112.1","Cell RNA - BJ [nTPM]":"149.4","Cell RNA - BJ hTERT+ [nTPM]":"362.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"161.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"182.8","Cell RNA - CACO-2 [nTPM]":"147.5","Cell RNA - CAPAN-2 [nTPM]":"2596.6","Cell RNA - Daudi [nTPM]":"49.2","Cell RNA - EFO-21 [nTPM]":"376.8","Cell RNA - fHDF\/TERT166 [nTPM]":"285.8","Cell RNA - GAMG [nTPM]":"1265.6","Cell RNA - HaCaT [nTPM]":"1072.2","Cell RNA - HAP1 [nTPM]":"63.7","Cell RNA - HBEC3-KT [nTPM]":"142.6","Cell RNA - HBF TERT88 [nTPM]":"35.8","Cell RNA - HDLM-2 [nTPM]":"206.7","Cell RNA - HEK 293 [nTPM]":"222.9","Cell RNA - HEL [nTPM]":"70.4","Cell RNA - HeLa [nTPM]":"92.5","Cell RNA - Hep G2 [nTPM]":"196.5","Cell RNA - HHSteC [nTPM]":"736.2","Cell RNA - HL-60 [nTPM]":"171.4","Cell RNA - HMC-1 [nTPM]":"787.7","Cell RNA - HSkMC [nTPM]":"350.9","Cell RNA - hTCEpi [nTPM]":"621.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"82.5","Cell RNA - hTERT-HME1 [nTPM]":"136.9","Cell RNA - hTERT-RPE1 [nTPM]":"2780.1","Cell RNA - HUVEC TERT2 [nTPM]":"128.2","Cell RNA - JURKAT [nTPM]":"62.1","Cell RNA - K-562 [nTPM]":"89.2","Cell RNA - Karpas-707 [nTPM]":"267.6","Cell RNA - LHCN-M2 [nTPM]":"263.3","Cell RNA - MCF7 [nTPM]":"832.6","Cell RNA - MOLT-4 [nTPM]":"47.0","Cell RNA - NB-4 [nTPM]":"110.9","Cell RNA - NTERA-2 [nTPM]":"153.1","Cell RNA - OE19 [nTPM]":"719.7","Cell RNA - PC-3 [nTPM]":"247.9","Cell RNA - REH [nTPM]":"62.5","Cell RNA - RH-30 [nTPM]":"72.5","Cell RNA - RPMI-8226 [nTPM]":"191.2","Cell RNA - RPTEC TERT1 [nTPM]":"586.6","Cell RNA - RT4 [nTPM]":"610.8","Cell RNA - SCLC-21H [nTPM]":"84.2","Cell RNA - SH-SY5Y [nTPM]":"94.8","Cell RNA - SiHa [nTPM]":"173.3","Cell RNA - SK-BR-3 [nTPM]":"2488.5","Cell RNA - SK-MEL-30 [nTPM]":"535.0","Cell RNA - SuSa [nTPM]":"68.6","Cell RNA - T-47d [nTPM]":"1022.8","Cell RNA - THP-1 [nTPM]":"232.6","Cell RNA - TIME [nTPM]":"170.3","Cell RNA - U-138 MG [nTPM]":"556.8","Cell RNA - U-2 OS [nTPM]":"92.9","Cell RNA - U-2197 [nTPM]":"79.0","Cell RNA - U-251 MG [nTPM]":"216.7","Cell RNA - U-266\/70 [nTPM]":"432.0","Cell RNA - U-266\/84 [nTPM]":"382.3","Cell RNA - U-698 [nTPM]":"26.8","Cell RNA - U-87 MG [nTPM]":"867.7","Cell RNA - U-937 [nTPM]":"468.6","Cell RNA - WM-115 [nTPM]":"509.6","Blood RNA - basophil [nTPM]":"211.2","Blood RNA - classical monocyte [nTPM]":"578.7","Blood RNA - eosinophil [nTPM]":"170.1","Blood RNA - gdT-cell [nTPM]":"156.5","Blood RNA - intermediate monocyte [nTPM]":"309.9","Blood RNA - MAIT T-cell [nTPM]":"90.6","Blood RNA - memory B-cell [nTPM]":"28.8","Blood RNA - memory CD4 T-cell [nTPM]":"72.1","Blood RNA - memory CD8 T-cell [nTPM]":"110.3","Blood RNA - myeloid DC [nTPM]":"144.5","Blood RNA - naive B-cell [nTPM]":"18.8","Blood RNA - naive CD4 T-cell [nTPM]":"82.5","Blood RNA - naive CD8 T-cell [nTPM]":"107.4","Blood RNA - neutrophil [nTPM]":"319.5","Blood RNA - NK-cell [nTPM]":"192.3","Blood RNA - non-classical monocyte [nTPM]":"265.2","Blood RNA - plasmacytoid DC [nTPM]":"120.3","Blood RNA - T-reg [nTPM]":"89.2","Blood RNA - total PBMC [nTPM]":"489.1","Brain RNA - amygdala [nTPM]":"147.0","Brain RNA - basal ganglia [nTPM]":"181.9","Brain RNA - cerebellum [nTPM]":"186.0","Brain RNA - cerebral cortex [nTPM]":"156.5","Brain RNA - hippocampal formation [nTPM]":"187.8","Brain RNA - hypothalamus [nTPM]":"223.6","Brain RNA - medulla oblongata [nTPM]":"247.6","Brain RNA - midbrain [nTPM]":"206.6","Brain RNA - pons [nTPM]":"228.6","Brain RNA - spinal cord [nTPM]":"188.9","Brain RNA - thalamus [nTPM]":"334.4","Brain RNA - white matter [nTPM]":"367.1","Single Cell Type RNA - Adipocytes [nTPM]":"139.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"112.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"228.6","Single Cell Type RNA - Astrocytes [nTPM]":"48.3","Single Cell Type RNA - B-cells [nTPM]":"62.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"223.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"473.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"71.7","Single Cell Type RNA - Bipolar cells [nTPM]":"168.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"108.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"251.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"314.5","Single Cell Type RNA - Club cells [nTPM]":"459.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"548.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.7","Single Cell Type RNA - dendritic cells [nTPM]":"156.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1475.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"109.5","Single Cell Type RNA - Ductal cells [nTPM]":"911.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"118.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.4","Single Cell Type RNA - Endothelial cells [nTPM]":"128.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"159.6","Single Cell Type RNA - Erythroid cells [nTPM]":"132.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"370.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"165.0","Single Cell Type RNA - Fibroblasts [nTPM]":"157.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"237.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"203.4","Single Cell Type RNA - granulocytes [nTPM]":"474.3","Single Cell Type RNA - Granulosa cells [nTPM]":"119.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"695.7","Single Cell Type RNA - Hepatocytes [nTPM]":"678.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"3763.5","Single Cell Type RNA - Horizontal cells [nTPM]":"264.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"418.2","Single Cell Type RNA - Ionocytes [nTPM]":"498.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1187.8","Single Cell Type RNA - Langerhans cells [nTPM]":"67.5","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"108.4","Single Cell Type RNA - Macrophages [nTPM]":"1512.6","Single Cell Type RNA - Melanocytes [nTPM]":"227.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"382.6","Single Cell Type RNA - Muller glia cells [nTPM]":"179.0","Single Cell Type RNA - NK-cells [nTPM]":"256.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"392.3","Single Cell Type RNA - Paneth cells [nTPM]":"832.5","Single Cell Type RNA - Peritubular cells [nTPM]":"128.2","Single Cell Type RNA - Plasma cells [nTPM]":"122.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"111.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1699.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"311.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"270.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"102.1","Single Cell Type RNA - Sertoli cells [nTPM]":"111.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"135.2","Single Cell Type RNA - Spermatocytes [nTPM]":"26.6","Single Cell Type RNA - Spermatogonia [nTPM]":"63.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"141.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"82.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"471.3","Single Cell Type RNA - T-cells [nTPM]":"155.0","Single Cell Type RNA - Theca cells [nTPM]":"96.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"399.1","Single Cell Type RNA - Urothelial cells [nTPM]":"357.8"},{"Gene":"CTSE","Gene synonym":[],"Ensembl":"ENSG00000196188","Gene description":"Cathepsin E","Uniprot":["P14091"],"Chromosome":"1","Position":"206008535-206023909","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"stomach 1":"1168.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"105.8","Exocrine glandular cells":"262.8","Gastric mucus-secreting cells":"553.5","Pancreatic endocrine cells":"260.0","Paneth cells":"208.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"297.4","stomach cancer":"200.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"46","RNA cell line specific nTPM":{"OE19":"1799.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012674","HPA012940","CAB032687"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB032687":"AB_637901","HPA012674":null,"HPA012940":"AB_2668773"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"30.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"229.8","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"49.7","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"25.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"55.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"1168.3","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"8.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"10.7","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"20.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"2.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"3.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"1.5","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"1799.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"39.4","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"105.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"42.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"52.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"60.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"262.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"553.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"260.0","Single Cell Type RNA - Paneth cells [nTPM]":"208.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HM13","Gene synonym":["dJ324O17.1","H13","IMP1","IMPAS","PSENL3","PSL3","SPP","SPPL1"],"Ensembl":"ENSG00000101294","Gene description":"Histocompatibility minor 13","Uniprot":["Q8TCT9"],"Chromosome":"20","Position":"31514410-31577923","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"324.9","Plasma cells":"400.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045089","HPA056062"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045089":"AB_10962054","HPA056062":"AB_2683022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"78.6","Tissue RNA - adrenal gland [nTPM]":"102.9","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"60.9","Tissue RNA - basal ganglia [nTPM]":"13.5","Tissue RNA - bone marrow [nTPM]":"61.7","Tissue RNA - breast [nTPM]":"63.4","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"15.7","Tissue RNA - cervix [nTPM]":"100.0","Tissue RNA - choroid plexus [nTPM]":"42.4","Tissue RNA - colon [nTPM]":"54.5","Tissue RNA - duodenum [nTPM]":"52.6","Tissue RNA - endometrium 1 [nTPM]":"72.9","Tissue RNA - epididymis [nTPM]":"111.4","Tissue RNA - esophagus [nTPM]":"128.6","Tissue RNA - fallopian tube [nTPM]":"70.4","Tissue RNA - gallbladder [nTPM]":"46.7","Tissue RNA - heart muscle [nTPM]":"55.9","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"17.1","Tissue RNA - kidney [nTPM]":"61.4","Tissue RNA - liver [nTPM]":"136.1","Tissue RNA - lung [nTPM]":"83.7","Tissue RNA - lymph node [nTPM]":"40.7","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"17.9","Tissue RNA - ovary [nTPM]":"59.2","Tissue RNA - pancreas [nTPM]":"241.1","Tissue RNA - parathyroid gland [nTPM]":"68.8","Tissue RNA - pituitary gland [nTPM]":"90.0","Tissue RNA - placenta [nTPM]":"64.6","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"66.0","Tissue RNA - rectum [nTPM]":"44.4","Tissue RNA - retina [nTPM]":"20.8","Tissue RNA - salivary gland [nTPM]":"217.7","Tissue RNA - seminal vesicle [nTPM]":"80.3","Tissue RNA - skeletal muscle [nTPM]":"44.6","Tissue RNA - skin 1 [nTPM]":"51.6","Tissue RNA - small intestine [nTPM]":"52.1","Tissue RNA - smooth muscle [nTPM]":"49.1","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"70.2","Tissue RNA - stomach 1 [nTPM]":"92.5","Tissue RNA - testis [nTPM]":"21.9","Tissue RNA - thalamus [nTPM]":"23.9","Tissue RNA - thymus [nTPM]":"30.5","Tissue RNA - thyroid gland [nTPM]":"74.7","Tissue RNA - tongue [nTPM]":"14.1","Tissue RNA - tonsil [nTPM]":"54.2","Tissue RNA - urinary bladder [nTPM]":"64.9","Tissue RNA - vagina [nTPM]":"72.2","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"143.8","Cell RNA - A549 [nTPM]":"147.6","Cell RNA - AF22 [nTPM]":"56.6","Cell RNA - AN3-CA [nTPM]":"87.7","Cell RNA - ASC diff [nTPM]":"260.2","Cell RNA - ASC TERT1 [nTPM]":"163.5","Cell RNA - BEWO [nTPM]":"197.6","Cell RNA - BJ [nTPM]":"239.0","Cell RNA - BJ hTERT+ [nTPM]":"221.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"159.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"162.8","Cell RNA - CACO-2 [nTPM]":"287.3","Cell RNA - CAPAN-2 [nTPM]":"166.8","Cell RNA - Daudi [nTPM]":"90.4","Cell RNA - EFO-21 [nTPM]":"312.8","Cell RNA - fHDF\/TERT166 [nTPM]":"262.7","Cell RNA - GAMG [nTPM]":"209.7","Cell RNA - HaCaT [nTPM]":"253.8","Cell RNA - HAP1 [nTPM]":"74.9","Cell RNA - HBEC3-KT [nTPM]":"162.0","Cell RNA - HBF TERT88 [nTPM]":"97.7","Cell RNA - HDLM-2 [nTPM]":"46.2","Cell RNA - HEK 293 [nTPM]":"112.0","Cell RNA - HEL [nTPM]":"201.3","Cell RNA - HeLa [nTPM]":"99.7","Cell RNA - Hep G2 [nTPM]":"179.3","Cell RNA - HHSteC [nTPM]":"287.0","Cell RNA - HL-60 [nTPM]":"118.1","Cell RNA - HMC-1 [nTPM]":"78.1","Cell RNA - HSkMC [nTPM]":"152.5","Cell RNA - hTCEpi [nTPM]":"103.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"133.7","Cell RNA - hTERT-HME1 [nTPM]":"182.7","Cell RNA - hTERT-RPE1 [nTPM]":"159.0","Cell RNA - HUVEC TERT2 [nTPM]":"124.5","Cell RNA - JURKAT [nTPM]":"56.0","Cell RNA - K-562 [nTPM]":"90.2","Cell RNA - Karpas-707 [nTPM]":"364.0","Cell RNA - LHCN-M2 [nTPM]":"148.8","Cell RNA - MCF7 [nTPM]":"170.3","Cell RNA - MOLT-4 [nTPM]":"100.0","Cell RNA - NB-4 [nTPM]":"84.0","Cell RNA - NTERA-2 [nTPM]":"67.8","Cell RNA - OE19 [nTPM]":"234.9","Cell RNA - PC-3 [nTPM]":"248.5","Cell RNA - REH [nTPM]":"63.6","Cell RNA - RH-30 [nTPM]":"272.6","Cell RNA - RPMI-8226 [nTPM]":"436.5","Cell RNA - RPTEC TERT1 [nTPM]":"154.4","Cell RNA - RT4 [nTPM]":"75.6","Cell RNA - SCLC-21H [nTPM]":"76.3","Cell RNA - SH-SY5Y [nTPM]":"90.4","Cell RNA - SiHa [nTPM]":"243.5","Cell RNA - SK-BR-3 [nTPM]":"234.9","Cell RNA - SK-MEL-30 [nTPM]":"199.2","Cell RNA - SuSa [nTPM]":"56.4","Cell RNA - T-47d [nTPM]":"182.0","Cell RNA - THP-1 [nTPM]":"109.5","Cell RNA - TIME [nTPM]":"153.3","Cell RNA - U-138 MG [nTPM]":"243.1","Cell RNA - U-2 OS [nTPM]":"129.8","Cell RNA - U-2197 [nTPM]":"246.3","Cell RNA - U-251 MG [nTPM]":"136.2","Cell RNA - U-266\/70 [nTPM]":"225.5","Cell RNA - U-266\/84 [nTPM]":"145.5","Cell RNA - U-698 [nTPM]":"71.7","Cell RNA - U-87 MG [nTPM]":"328.7","Cell RNA - U-937 [nTPM]":"413.0","Cell RNA - WM-115 [nTPM]":"219.4","Blood RNA - basophil [nTPM]":"117.7","Blood RNA - classical monocyte [nTPM]":"380.9","Blood RNA - eosinophil [nTPM]":"190.8","Blood RNA - gdT-cell [nTPM]":"116.7","Blood RNA - intermediate monocyte [nTPM]":"372.6","Blood RNA - MAIT T-cell [nTPM]":"159.7","Blood RNA - memory B-cell [nTPM]":"91.9","Blood RNA - memory CD4 T-cell [nTPM]":"108.0","Blood RNA - memory CD8 T-cell [nTPM]":"112.9","Blood RNA - myeloid DC [nTPM]":"260.8","Blood RNA - naive B-cell [nTPM]":"74.4","Blood RNA - naive CD4 T-cell [nTPM]":"70.6","Blood RNA - naive CD8 T-cell [nTPM]":"84.1","Blood RNA - neutrophil [nTPM]":"282.8","Blood RNA - NK-cell [nTPM]":"117.5","Blood RNA - non-classical monocyte [nTPM]":"363.7","Blood RNA - plasmacytoid DC [nTPM]":"271.9","Blood RNA - T-reg [nTPM]":"104.1","Blood RNA - total PBMC [nTPM]":"374.1","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"13.5","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"15.7","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"17.1","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"17.9","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"23.9","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"67.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.4","Single Cell Type RNA - Astrocytes [nTPM]":"23.8","Single Cell Type RNA - B-cells [nTPM]":"78.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"127.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"45.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"102.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"123.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"154.0","Single Cell Type RNA - dendritic cells [nTPM]":"70.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"115.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"145.6","Single Cell Type RNA - Early spermatids [nTPM]":"15.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"111.5","Single Cell Type RNA - Endothelial cells [nTPM]":"60.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"61.5","Single Cell Type RNA - Erythroid cells [nTPM]":"38.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"40.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"169.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"139.0","Single Cell Type RNA - Fibroblasts [nTPM]":"93.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"128.4","Single Cell Type RNA - granulocytes [nTPM]":"42.4","Single Cell Type RNA - Granulosa cells [nTPM]":"55.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.2","Single Cell Type RNA - Hepatocytes [nTPM]":"86.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"324.9","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"134.5","Single Cell Type RNA - Ionocytes [nTPM]":"63.1","Single Cell Type RNA - Kupffer cells [nTPM]":"81.2","Single Cell Type RNA - Langerhans cells [nTPM]":"83.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.9","Single Cell Type RNA - Leydig cells [nTPM]":"60.6","Single Cell Type RNA - Macrophages [nTPM]":"106.1","Single Cell Type RNA - Melanocytes [nTPM]":"65.8","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"77.4","Single Cell Type RNA - Muller glia cells [nTPM]":"52.2","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"144.3","Single Cell Type RNA - Paneth cells [nTPM]":"81.2","Single Cell Type RNA - Peritubular cells [nTPM]":"43.6","Single Cell Type RNA - Plasma cells [nTPM]":"400.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"54.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"51.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"79.2","Single Cell Type RNA - Spermatocytes [nTPM]":"26.1","Single Cell Type RNA - Spermatogonia [nTPM]":"26.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"213.6","Single Cell Type RNA - T-cells [nTPM]":"60.1","Single Cell Type RNA - Theca cells [nTPM]":"97.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"70.8","Single Cell Type RNA - Urothelial cells [nTPM]":"69.3"},{"Gene":"NAPSA","Gene synonym":["KAP","Kdap","NAP1","NAPA"],"Ensembl":"ENSG00000131400","Gene description":"Napsin A aspartic peptidase","Uniprot":["O96009"],"Chromosome":"19","Position":"50358477-50365830","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lung":"1075.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 2":"3072.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"lung cancer":"249.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"8.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"4.3","dendritic cells":"8.7"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"31","RNA cell line specific nTPM":{"U-698":"42.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009591","HPA045280","HPA047236","HPA047744"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009591":null,"HPA045280":"AB_2679283","HPA047236":"AB_2679993","HPA047744":"AB_2680143"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-5"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"106.3","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1075.5","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"1.5","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.1","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"1.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"42.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"8.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"522.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3072.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"45.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"47.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"69.4","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"9.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"276.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PGA3","Gene synonym":[],"Ensembl":"ENSG00000229859","Gene description":"Pepsinogen A3","Uniprot":["P0DJD8"],"Chromosome":"11","Position":"61203307-61213098","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Digestion"],"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"613","RNA tissue specific nTPM":{"stomach 1":"89073.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"526","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"3263.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"498","RNA cancer specific FPKM":{"stomach cancer":"24.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"2.9"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"2.8","THP-1":"1.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026358","HPA046875"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026358":null,"HPA046875":"AB_2679851"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"80.5","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"18.2","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"145.3","Tissue RNA - duodenum [nTPM]":"1.3","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"96.4","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"16.2","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"89073.4","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3263.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PGA4","Gene synonym":[],"Ensembl":"ENSG00000229183","Gene description":"Pepsinogen A4","Uniprot":["P0DJD7"],"Chromosome":"11","Position":"61222349-61231694","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Digestion"],"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"1281","RNA tissue specific nTPM":{"stomach 1":"66596.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Exocrine glandular cells":"109.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"classical monocyte":"9.9","intermediate monocyte":"10.9","non-classical monocyte":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"monocytes":"10.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"BJ hTERT+":"26.1","HMC-1":"9.5","THP-1":"15.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046875"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046875":"AB_2679851"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"52.0","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"30.3","Tissue RNA - liver [nTPM]":"11.7","Tissue RNA - lung [nTPM]":"37.9","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"4.1","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.9","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"5.2","Tissue RNA - stomach 1 [nTPM]":"66596.4","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"26.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"9.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"2.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"15.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"10.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"109.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PGA5","Gene synonym":[],"Ensembl":"ENSG00000256713","Gene description":"Pepsinogen A5","Uniprot":["P0DJD9"],"Chromosome":"11","Position":"61241175-61251444","Protein class":["Enzymes","FDA approved drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Digestion"],"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"2014","RNA tissue specific nTPM":{"stomach 1":"39870.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"77","RNA single cell type specific nTPM":{"Exocrine glandular cells":"4383.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"stomach cancer":"15.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"29","RNA blood cell specific nTPM":{"classical monocyte":"1.8","intermediate monocyte":"4.3","non-classical monocyte":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"monocytes":"4.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"BJ hTERT+":"28.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046875"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046875":"AB_2679851"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"19.7","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"7.0","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"2.4","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"39870.8","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"28.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"4.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4383.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"25.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PGC","Gene synonym":[],"Ensembl":"ENSG00000096088","Gene description":"Progastricsin","Uniprot":["P20142"],"Chromosome":"6","Position":"41736711-41754109","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Digestion"],"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"45","RNA tissue specific nTPM":{"stomach 1":"59821.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"5737.5","Pancreatic endocrine cells":"1449.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1050.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Hep G2":"253.1","OE19":"152.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031717","HPA031718"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031717":"AB_10670130","HPA031718":"AB_10610148"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.4","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"6.6","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"6.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"1327.3","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"85.5","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"4.9","Tissue RNA - liver [nTPM]":"11.0","Tissue RNA - lung [nTPM]":"378.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"136.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"83.9","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"437.7","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"59821.1","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"15.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"253.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"6.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.5","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"5.7","Cell RNA - OE19 [nTPM]":"152.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"6.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.7","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"335.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"131.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5737.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1449.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"85.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"4.2"},{"Gene":"PSEN1","Gene synonym":["AD3","FAD","PS1","S182"],"Ensembl":"ENSG00000080815","Gene description":"Presenilin 1","Uniprot":["P49768"],"Chromosome":"14","Position":"73136418-73223691","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"395.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006844","HPA030760","HPA067496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"CAB006844":null,"HPA030760":"AB_10696211","HPA067496":"AB_2685853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"44.3","Tissue RNA - appendix [nTPM]":"26.5","Tissue RNA - basal ganglia [nTPM]":"80.7","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"56.0","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"48.9","Tissue RNA - colon [nTPM]":"49.5","Tissue RNA - duodenum [nTPM]":"50.2","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"47.4","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"35.5","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"73.0","Tissue RNA - midbrain [nTPM]":"63.8","Tissue RNA - ovary [nTPM]":"22.0","Tissue RNA - pancreas [nTPM]":"22.9","Tissue RNA - parathyroid gland [nTPM]":"35.1","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"24.3","Tissue RNA - rectum [nTPM]":"46.3","Tissue RNA - retina [nTPM]":"23.4","Tissue RNA - salivary gland [nTPM]":"22.9","Tissue RNA - seminal vesicle [nTPM]":"23.4","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"38.2","Tissue RNA - small intestine [nTPM]":"49.0","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"55.7","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"31.0","Tissue RNA - testis [nTPM]":"32.5","Tissue RNA - thalamus [nTPM]":"60.8","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"36.9","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"30.7","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"119.1","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"55.9","Cell RNA - AF22 [nTPM]":"50.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"49.9","Cell RNA - BEWO [nTPM]":"46.7","Cell RNA - BJ [nTPM]":"52.5","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.7","Cell RNA - CACO-2 [nTPM]":"69.9","Cell RNA - CAPAN-2 [nTPM]":"88.9","Cell RNA - Daudi [nTPM]":"23.7","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"50.5","Cell RNA - GAMG [nTPM]":"43.0","Cell RNA - HaCaT [nTPM]":"94.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"40.1","Cell RNA - HBF TERT88 [nTPM]":"57.3","Cell RNA - HDLM-2 [nTPM]":"54.6","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"34.4","Cell RNA - HHSteC [nTPM]":"63.8","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"50.7","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"71.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"54.4","Cell RNA - hTERT-RPE1 [nTPM]":"48.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.2","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"31.0","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"21.0","Cell RNA - NB-4 [nTPM]":"35.7","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"64.5","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"30.2","Cell RNA - RPTEC TERT1 [nTPM]":"73.7","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"38.3","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"53.0","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"45.4","Cell RNA - T-47d [nTPM]":"66.3","Cell RNA - THP-1 [nTPM]":"60.7","Cell RNA - TIME [nTPM]":"45.7","Cell RNA - U-138 MG [nTPM]":"53.1","Cell RNA - U-2 OS [nTPM]":"43.5","Cell RNA - U-2197 [nTPM]":"44.1","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"44.9","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"33.3","Blood RNA - basophil [nTPM]":"126.8","Blood RNA - classical monocyte [nTPM]":"94.5","Blood RNA - eosinophil [nTPM]":"96.3","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"106.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"23.1","Blood RNA - memory CD4 T-cell [nTPM]":"22.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.0","Blood RNA - myeloid DC [nTPM]":"83.4","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"129.3","Blood RNA - NK-cell [nTPM]":"42.8","Blood RNA - non-classical monocyte [nTPM]":"125.0","Blood RNA - plasmacytoid DC [nTPM]":"43.6","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"70.3","Brain RNA - amygdala [nTPM]":"44.3","Brain RNA - basal ganglia [nTPM]":"80.7","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"56.0","Brain RNA - hippocampal formation [nTPM]":"47.4","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"73.0","Brain RNA - midbrain [nTPM]":"63.8","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"55.7","Brain RNA - thalamus [nTPM]":"60.8","Brain RNA - white matter [nTPM]":"119.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - dendritic cells [nTPM]":"30.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"24.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"50.5","Single Cell Type RNA - Langerhans cells [nTPM]":"40.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"52.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"395.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"58.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.9","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.3","Single Cell Type RNA - Urothelial cells [nTPM]":"51.5"},{"Gene":"PSEN2","Gene synonym":["AD3L","AD4","PS2","STM2"],"Ensembl":"ENSG00000143801","Gene description":"Presenilin 2","Uniprot":["P49810"],"Chromosome":"1","Position":"226870184-226927726","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"36.7","Syncytiotrophoblasts":"45.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"10.5","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"10.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"12.8","Tissue RNA - pancreas [nTPM]":"45.5","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"13.6","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"10.4","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"16.7","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"9.7","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"14.1","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"7.2","Cell RNA - AN3-CA [nTPM]":"21.9","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"12.4","Cell RNA - BJ hTERT+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.9","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.8","Cell RNA - GAMG [nTPM]":"10.5","Cell RNA - HaCaT [nTPM]":"7.9","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"11.9","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"13.6","Cell RNA - HEK 293 [nTPM]":"20.7","Cell RNA - HEL [nTPM]":"8.7","Cell RNA - HeLa [nTPM]":"10.5","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"15.4","Cell RNA - HL-60 [nTPM]":"7.5","Cell RNA - HMC-1 [nTPM]":"15.7","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.9","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"18.1","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"10.0","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"22.6","Cell RNA - RPMI-8226 [nTPM]":"26.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"9.7","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"51.6","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"26.5","Cell RNA - THP-1 [nTPM]":"13.1","Cell RNA - TIME [nTPM]":"8.5","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"8.9","Cell RNA - U-2197 [nTPM]":"9.9","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"25.6","Cell RNA - U-266\/84 [nTPM]":"45.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"37.4","Blood RNA - classical monocyte [nTPM]":"8.7","Blood RNA - eosinophil [nTPM]":"18.4","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"9.7","Blood RNA - MAIT T-cell [nTPM]":"5.1","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"11.4","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"20.0","Blood RNA - non-classical monocyte [nTPM]":"30.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"5.2","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"11.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.1","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"8.2","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.9","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"9.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"6.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.8","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"6.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"REN","Gene synonym":[],"Ensembl":"ENSG00000143839","Gene description":"Renin","Uniprot":["P00797"],"Chromosome":"1","Position":"204154819-204190324","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"kidney":"162.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"6.8","Late spermatids":"28.4","Paneth cells":"5.6","Smooth muscle cells":"10.7","Urothelial cells":"7.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"39.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"1.0","BJ":"2.0","HMC-1":"2.6","SK-BR-3":"1.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005131"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":692000,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005131":"AB_1079174"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"162.2","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"16.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"15.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"5.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"28.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"5.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"7.0"},{"Gene":"SPPL2A","Gene synonym":["IMP3","PSL2"],"Ensembl":"ENSG00000138600","Gene description":"Signal peptide peptidase like 2A","Uniprot":["Q8TCT8"],"Chromosome":"15","Position":"50702266-50765709","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036062","HPA067304"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036062":"AB_10611670","HPA067304":"AB_2685820"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.1","Tissue RNA - adrenal gland [nTPM]":"34.7","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"57.6","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"54.5","Tissue RNA - breast [nTPM]":"32.0","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"36.6","Tissue RNA - choroid plexus [nTPM]":"48.6","Tissue RNA - colon [nTPM]":"93.4","Tissue RNA - duodenum [nTPM]":"79.6","Tissue RNA - endometrium 1 [nTPM]":"27.9","Tissue RNA - epididymis [nTPM]":"21.5","Tissue RNA - esophagus [nTPM]":"26.5","Tissue RNA - fallopian tube [nTPM]":"26.8","Tissue RNA - gallbladder [nTPM]":"39.4","Tissue RNA - heart muscle [nTPM]":"37.1","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"12.3","Tissue RNA - kidney [nTPM]":"57.9","Tissue RNA - liver [nTPM]":"107.0","Tissue RNA - lung [nTPM]":"43.4","Tissue RNA - lymph node [nTPM]":"40.2","Tissue RNA - medulla oblongata [nTPM]":"15.3","Tissue RNA - midbrain [nTPM]":"12.8","Tissue RNA - ovary [nTPM]":"13.6","Tissue RNA - pancreas [nTPM]":"63.7","Tissue RNA - parathyroid gland [nTPM]":"158.5","Tissue RNA - pituitary gland [nTPM]":"13.0","Tissue RNA - placenta [nTPM]":"54.1","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"29.5","Tissue RNA - rectum [nTPM]":"82.8","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"44.5","Tissue RNA - seminal vesicle [nTPM]":"32.6","Tissue RNA - skeletal muscle [nTPM]":"109.3","Tissue RNA - skin 1 [nTPM]":"25.2","Tissue RNA - small intestine [nTPM]":"67.6","Tissue RNA - smooth muscle [nTPM]":"41.0","Tissue RNA - spinal cord [nTPM]":"11.2","Tissue RNA - spleen [nTPM]":"37.3","Tissue RNA - stomach 1 [nTPM]":"41.7","Tissue RNA - testis [nTPM]":"18.5","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"39.5","Tissue RNA - thyroid gland [nTPM]":"35.2","Tissue RNA - tongue [nTPM]":"81.8","Tissue RNA - tonsil [nTPM]":"41.7","Tissue RNA - urinary bladder [nTPM]":"51.7","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"14.5","Cell RNA - A-431 [nTPM]":"57.3","Cell RNA - A549 [nTPM]":"96.9","Cell RNA - AF22 [nTPM]":"37.0","Cell RNA - AN3-CA [nTPM]":"49.2","Cell RNA - ASC diff [nTPM]":"142.3","Cell RNA - ASC TERT1 [nTPM]":"84.3","Cell RNA - BEWO [nTPM]":"58.2","Cell RNA - BJ [nTPM]":"89.1","Cell RNA - BJ hTERT+ [nTPM]":"149.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"114.1","Cell RNA - CACO-2 [nTPM]":"113.1","Cell RNA - CAPAN-2 [nTPM]":"64.3","Cell RNA - Daudi [nTPM]":"35.1","Cell RNA - EFO-21 [nTPM]":"65.0","Cell RNA - fHDF\/TERT166 [nTPM]":"176.3","Cell RNA - GAMG [nTPM]":"120.7","Cell RNA - HaCaT [nTPM]":"83.5","Cell RNA - HAP1 [nTPM]":"45.2","Cell RNA - HBEC3-KT [nTPM]":"54.3","Cell RNA - HBF TERT88 [nTPM]":"89.5","Cell RNA - HDLM-2 [nTPM]":"72.2","Cell RNA - HEK 293 [nTPM]":"27.5","Cell RNA - HEL [nTPM]":"67.0","Cell RNA - HeLa [nTPM]":"61.5","Cell RNA - Hep G2 [nTPM]":"58.9","Cell RNA - HHSteC [nTPM]":"117.4","Cell RNA - HL-60 [nTPM]":"42.0","Cell RNA - HMC-1 [nTPM]":"104.5","Cell RNA - HSkMC [nTPM]":"73.9","Cell RNA - hTCEpi [nTPM]":"98.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"66.8","Cell RNA - hTERT-HME1 [nTPM]":"106.7","Cell RNA - hTERT-RPE1 [nTPM]":"59.4","Cell RNA - HUVEC TERT2 [nTPM]":"80.2","Cell RNA - JURKAT [nTPM]":"37.7","Cell RNA - K-562 [nTPM]":"51.3","Cell RNA - Karpas-707 [nTPM]":"134.2","Cell RNA - LHCN-M2 [nTPM]":"107.6","Cell RNA - MCF7 [nTPM]":"131.5","Cell RNA - MOLT-4 [nTPM]":"20.1","Cell RNA - NB-4 [nTPM]":"16.2","Cell RNA - NTERA-2 [nTPM]":"15.8","Cell RNA - OE19 [nTPM]":"90.8","Cell RNA - PC-3 [nTPM]":"22.0","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"57.3","Cell RNA - RPMI-8226 [nTPM]":"77.6","Cell RNA - RPTEC TERT1 [nTPM]":"109.7","Cell RNA - RT4 [nTPM]":"130.4","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"33.4","Cell RNA - SiHa [nTPM]":"54.0","Cell RNA - SK-BR-3 [nTPM]":"102.7","Cell RNA - SK-MEL-30 [nTPM]":"63.4","Cell RNA - SuSa [nTPM]":"74.0","Cell RNA - T-47d [nTPM]":"73.2","Cell RNA - THP-1 [nTPM]":"81.6","Cell RNA - TIME [nTPM]":"98.9","Cell RNA - U-138 MG [nTPM]":"128.7","Cell RNA - U-2 OS [nTPM]":"51.7","Cell RNA - U-2197 [nTPM]":"83.7","Cell RNA - U-251 MG [nTPM]":"106.7","Cell RNA - U-266\/70 [nTPM]":"54.0","Cell RNA - U-266\/84 [nTPM]":"100.2","Cell RNA - U-698 [nTPM]":"38.8","Cell RNA - U-87 MG [nTPM]":"58.1","Cell RNA - U-937 [nTPM]":"69.4","Cell RNA - WM-115 [nTPM]":"90.3","Blood RNA - basophil [nTPM]":"48.7","Blood RNA - classical monocyte [nTPM]":"52.3","Blood RNA - eosinophil [nTPM]":"48.9","Blood RNA - gdT-cell [nTPM]":"27.9","Blood RNA - intermediate monocyte [nTPM]":"48.6","Blood RNA - MAIT T-cell [nTPM]":"17.4","Blood RNA - memory B-cell [nTPM]":"18.3","Blood RNA - memory CD4 T-cell [nTPM]":"22.3","Blood RNA - memory CD8 T-cell [nTPM]":"25.5","Blood RNA - myeloid DC [nTPM]":"37.4","Blood RNA - naive B-cell [nTPM]":"19.2","Blood RNA - naive CD4 T-cell [nTPM]":"12.4","Blood RNA - naive CD8 T-cell [nTPM]":"20.5","Blood RNA - neutrophil [nTPM]":"37.7","Blood RNA - NK-cell [nTPM]":"23.5","Blood RNA - non-classical monocyte [nTPM]":"56.6","Blood RNA - plasmacytoid DC [nTPM]":"33.1","Blood RNA - T-reg [nTPM]":"30.4","Blood RNA - total PBMC [nTPM]":"50.2","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"12.3","Brain RNA - medulla oblongata [nTPM]":"15.3","Brain RNA - midbrain [nTPM]":"12.8","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"11.2","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"14.5","Single Cell Type RNA - Adipocytes [nTPM]":"66.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.9","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"51.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"79.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Bipolar cells [nTPM]":"14.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"77.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"44.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.5","Single Cell Type RNA - dendritic cells [nTPM]":"72.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"215.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"87.1","Single Cell Type RNA - Early spermatids [nTPM]":"18.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"107.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.6","Single Cell Type RNA - Endothelial cells [nTPM]":"59.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"38.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"167.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"88.3","Single Cell Type RNA - Fibroblasts [nTPM]":"74.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.3","Single Cell Type RNA - granulocytes [nTPM]":"45.7","Single Cell Type RNA - Granulosa cells [nTPM]":"20.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"124.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"85.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"86.5","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"68.7","Single Cell Type RNA - Langerhans cells [nTPM]":"55.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.0","Single Cell Type RNA - Leydig cells [nTPM]":"44.7","Single Cell Type RNA - Macrophages [nTPM]":"83.0","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"134.5","Single Cell Type RNA - Muller glia cells [nTPM]":"27.5","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"131.9","Single Cell Type RNA - Paneth cells [nTPM]":"127.3","Single Cell Type RNA - Peritubular cells [nTPM]":"36.5","Single Cell Type RNA - Plasma cells [nTPM]":"49.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"143.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"88.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.6","Single Cell Type RNA - Spermatocytes [nTPM]":"31.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"204.5","Single Cell Type RNA - T-cells [nTPM]":"60.6","Single Cell Type RNA - Theca cells [nTPM]":"30.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"76.0","Single Cell Type RNA - Urothelial cells [nTPM]":"94.1"},{"Gene":"SPPL2B","Gene synonym":["IMP4","KIAA1532","PSL1"],"Ensembl":"ENSG00000005206","Gene description":"Signal peptide peptidase like 2B","Uniprot":["Q8TCT7"],"Chromosome":"19","Position":"2328615-2355095","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"109.1","Late spermatids":"107.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005592","HPA039292"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB005592":"AB_325074","HPA039292":"AB_2676429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"23.2","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"16.7","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"29.1","Tissue RNA - breast [nTPM]":"27.4","Tissue RNA - cerebellum [nTPM]":"15.5","Tissue RNA - cerebral cortex [nTPM]":"18.6","Tissue RNA - cervix [nTPM]":"28.4","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"43.4","Tissue RNA - duodenum [nTPM]":"41.6","Tissue RNA - endometrium 1 [nTPM]":"26.4","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"34.0","Tissue RNA - gallbladder [nTPM]":"10.7","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"12.1","Tissue RNA - kidney [nTPM]":"35.9","Tissue RNA - liver [nTPM]":"33.0","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"20.7","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"15.6","Tissue RNA - ovary [nTPM]":"27.2","Tissue RNA - pancreas [nTPM]":"50.7","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"63.8","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"15.5","Tissue RNA - prostate [nTPM]":"32.5","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"7.1","Tissue RNA - salivary gland [nTPM]":"27.2","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"25.3","Tissue RNA - skin 1 [nTPM]":"28.9","Tissue RNA - small intestine [nTPM]":"52.6","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"13.2","Tissue RNA - spleen [nTPM]":"39.1","Tissue RNA - stomach 1 [nTPM]":"33.9","Tissue RNA - testis [nTPM]":"63.5","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"21.9","Tissue RNA - vagina [nTPM]":"20.9","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"25.9","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"19.5","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"8.9","Cell RNA - BEWO [nTPM]":"27.8","Cell RNA - BJ [nTPM]":"21.1","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"18.2","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"15.7","Cell RNA - EFO-21 [nTPM]":"19.4","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"7.1","Cell RNA - HaCaT [nTPM]":"21.7","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"18.4","Cell RNA - HEK 293 [nTPM]":"16.0","Cell RNA - HEL [nTPM]":"10.4","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"24.9","Cell RNA - HHSteC [nTPM]":"16.5","Cell RNA - HL-60 [nTPM]":"18.6","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"13.1","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.2","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"11.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"32.2","Cell RNA - K-562 [nTPM]":"17.3","Cell RNA - Karpas-707 [nTPM]":"39.0","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"18.4","Cell RNA - MOLT-4 [nTPM]":"20.2","Cell RNA - NB-4 [nTPM]":"23.6","Cell RNA - NTERA-2 [nTPM]":"20.4","Cell RNA - OE19 [nTPM]":"14.7","Cell RNA - PC-3 [nTPM]":"10.5","Cell RNA - REH [nTPM]":"33.4","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"43.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"41.0","Cell RNA - SCLC-21H [nTPM]":"19.4","Cell RNA - SH-SY5Y [nTPM]":"18.3","Cell RNA - SiHa [nTPM]":"21.2","Cell RNA - SK-BR-3 [nTPM]":"12.8","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"21.3","Cell RNA - THP-1 [nTPM]":"30.8","Cell RNA - TIME [nTPM]":"24.3","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"9.7","Cell RNA - U-2197 [nTPM]":"35.3","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"51.0","Cell RNA - U-266\/84 [nTPM]":"20.1","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"17.3","Cell RNA - U-937 [nTPM]":"21.4","Cell RNA - WM-115 [nTPM]":"24.5","Blood RNA - basophil [nTPM]":"11.5","Blood RNA - classical monocyte [nTPM]":"7.7","Blood RNA - eosinophil [nTPM]":"7.4","Blood RNA - gdT-cell [nTPM]":"6.2","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"8.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.0","Blood RNA - myeloid DC [nTPM]":"9.4","Blood RNA - naive B-cell [nTPM]":"12.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.9","Blood RNA - naive CD8 T-cell [nTPM]":"7.7","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"6.4","Blood RNA - non-classical monocyte [nTPM]":"5.4","Blood RNA - plasmacytoid DC [nTPM]":"17.0","Blood RNA - T-reg [nTPM]":"6.0","Blood RNA - total PBMC [nTPM]":"6.4","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"15.5","Brain RNA - cerebral cortex [nTPM]":"18.6","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"12.1","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"15.6","Brain RNA - pons [nTPM]":"15.5","Brain RNA - spinal cord [nTPM]":"13.2","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.2","Single Cell Type RNA - Astrocytes [nTPM]":"57.1","Single Cell Type RNA - B-cells [nTPM]":"30.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"26.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"50.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"51.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"14.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"40.7","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.8","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"109.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"39.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"15.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"63.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"107.7","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"10.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"8.0","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"49.9","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"11.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"57.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.8","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.8","Single Cell Type RNA - Urothelial cells [nTPM]":"6.0"},{"Gene":"SPPL2C","Gene synonym":["IMP5"],"Ensembl":"ENSG00000185294","Gene description":"Signal peptide peptidase like 2C","Uniprot":["Q8IUH8"],"Chromosome":"17","Position":"45844881-45847067","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"testis":"36.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"146","RNA single cell type specific nTPM":{"Early spermatids":"202.7","Late spermatids":"615.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077339"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077339":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"36.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"202.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"615.6","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SPPL3","Gene synonym":["DKFZP586C1324","IMP2","MGC126674","MGC126676","MGC90402","PSL4"],"Ensembl":"ENSG00000157837","Gene description":"Signal peptide peptidase like 3","Uniprot":["Q8TCT6"],"Chromosome":"12","Position":"120762510-120904358","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"192.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004194","HPA059958"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004194":"AB_2667171","HPA059958":"AB_2684179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.9","Tissue RNA - adrenal gland [nTPM]":"14.9","Tissue RNA - amygdala [nTPM]":"25.3","Tissue RNA - appendix [nTPM]":"11.9","Tissue RNA - basal ganglia [nTPM]":"28.1","Tissue RNA - bone marrow [nTPM]":"20.9","Tissue RNA - breast [nTPM]":"24.2","Tissue RNA - cerebellum [nTPM]":"29.0","Tissue RNA - cerebral cortex [nTPM]":"27.5","Tissue RNA - cervix [nTPM]":"30.0","Tissue RNA - choroid plexus [nTPM]":"13.1","Tissue RNA - colon [nTPM]":"26.7","Tissue RNA - duodenum [nTPM]":"18.2","Tissue RNA - endometrium 1 [nTPM]":"26.3","Tissue RNA - epididymis [nTPM]":"15.7","Tissue RNA - esophagus [nTPM]":"44.3","Tissue RNA - fallopian tube [nTPM]":"28.6","Tissue RNA - gallbladder [nTPM]":"18.7","Tissue RNA - heart muscle [nTPM]":"18.1","Tissue RNA - hippocampal formation [nTPM]":"25.4","Tissue RNA - hypothalamus [nTPM]":"30.6","Tissue RNA - kidney [nTPM]":"22.8","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"20.4","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"25.0","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"31.4","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"49.6","Tissue RNA - pituitary gland [nTPM]":"13.9","Tissue RNA - placenta [nTPM]":"28.4","Tissue RNA - pons [nTPM]":"26.1","Tissue RNA - prostate [nTPM]":"20.6","Tissue RNA - rectum [nTPM]":"27.2","Tissue RNA - retina [nTPM]":"15.5","Tissue RNA - salivary gland [nTPM]":"20.2","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"15.7","Tissue RNA - skin 1 [nTPM]":"56.5","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"29.6","Tissue RNA - spinal cord [nTPM]":"24.1","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"39.0","Tissue RNA - thalamus [nTPM]":"26.4","Tissue RNA - thymus [nTPM]":"32.7","Tissue RNA - thyroid gland [nTPM]":"31.2","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"28.6","Tissue RNA - vagina [nTPM]":"34.2","Tissue RNA - white matter [nTPM]":"31.4","Cell RNA - A-431 [nTPM]":"30.0","Cell RNA - A549 [nTPM]":"29.2","Cell RNA - AF22 [nTPM]":"43.4","Cell RNA - AN3-CA [nTPM]":"27.4","Cell RNA - ASC diff [nTPM]":"56.2","Cell RNA - ASC TERT1 [nTPM]":"37.7","Cell RNA - BEWO [nTPM]":"30.5","Cell RNA - BJ [nTPM]":"22.5","Cell RNA - BJ hTERT+ [nTPM]":"66.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"37.9","Cell RNA - CACO-2 [nTPM]":"30.5","Cell RNA - CAPAN-2 [nTPM]":"29.9","Cell RNA - Daudi [nTPM]":"27.4","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"39.4","Cell RNA - GAMG [nTPM]":"42.0","Cell RNA - HaCaT [nTPM]":"35.6","Cell RNA - HAP1 [nTPM]":"44.8","Cell RNA - HBEC3-KT [nTPM]":"48.4","Cell RNA - HBF TERT88 [nTPM]":"48.9","Cell RNA - HDLM-2 [nTPM]":"21.9","Cell RNA - HEK 293 [nTPM]":"27.5","Cell RNA - HEL [nTPM]":"23.6","Cell RNA - HeLa [nTPM]":"16.2","Cell RNA - Hep G2 [nTPM]":"23.4","Cell RNA - HHSteC [nTPM]":"59.2","Cell RNA - HL-60 [nTPM]":"27.4","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"38.1","Cell RNA - hTCEpi [nTPM]":"75.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.7","Cell RNA - hTERT-HME1 [nTPM]":"38.1","Cell RNA - hTERT-RPE1 [nTPM]":"56.0","Cell RNA - HUVEC TERT2 [nTPM]":"47.1","Cell RNA - JURKAT [nTPM]":"41.5","Cell RNA - K-562 [nTPM]":"26.5","Cell RNA - Karpas-707 [nTPM]":"13.4","Cell RNA - LHCN-M2 [nTPM]":"41.2","Cell RNA - MCF7 [nTPM]":"26.3","Cell RNA - MOLT-4 [nTPM]":"36.7","Cell RNA - NB-4 [nTPM]":"22.0","Cell RNA - NTERA-2 [nTPM]":"29.2","Cell RNA - OE19 [nTPM]":"27.8","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"21.6","Cell RNA - RH-30 [nTPM]":"36.6","Cell RNA - RPMI-8226 [nTPM]":"19.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.8","Cell RNA - RT4 [nTPM]":"83.8","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"31.9","Cell RNA - SiHa [nTPM]":"42.8","Cell RNA - SK-BR-3 [nTPM]":"19.6","Cell RNA - SK-MEL-30 [nTPM]":"34.7","Cell RNA - SuSa [nTPM]":"46.1","Cell RNA - T-47d [nTPM]":"58.9","Cell RNA - THP-1 [nTPM]":"18.7","Cell RNA - TIME [nTPM]":"35.4","Cell RNA - U-138 MG [nTPM]":"21.9","Cell RNA - U-2 OS [nTPM]":"29.5","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"17.1","Cell RNA - U-266\/70 [nTPM]":"30.9","Cell RNA - U-266\/84 [nTPM]":"60.3","Cell RNA - U-698 [nTPM]":"26.4","Cell RNA - U-87 MG [nTPM]":"32.5","Cell RNA - U-937 [nTPM]":"22.3","Cell RNA - WM-115 [nTPM]":"36.9","Blood RNA - basophil [nTPM]":"4.8","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"25.3","Brain RNA - basal ganglia [nTPM]":"28.1","Brain RNA - cerebellum [nTPM]":"29.0","Brain RNA - cerebral cortex [nTPM]":"27.5","Brain RNA - hippocampal formation [nTPM]":"25.4","Brain RNA - hypothalamus [nTPM]":"30.6","Brain RNA - medulla oblongata [nTPM]":"25.0","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"26.1","Brain RNA - spinal cord [nTPM]":"24.1","Brain RNA - thalamus [nTPM]":"26.4","Brain RNA - white matter [nTPM]":"31.4","Single Cell Type RNA - Adipocytes [nTPM]":"35.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"79.3","Single Cell Type RNA - B-cells [nTPM]":"25.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"55.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"37.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"19.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"47.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.9","Single Cell Type RNA - Endothelial cells [nTPM]":"33.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.1","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"97.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.0","Single Cell Type RNA - Fibroblasts [nTPM]":"33.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"68.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"33.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.3","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"112.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.7","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"38.1","Single Cell Type RNA - Langerhans cells [nTPM]":"39.3","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"34.5","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"79.6","Single Cell Type RNA - monocytes [nTPM]":"26.6","Single Cell Type RNA - Muller glia cells [nTPM]":"23.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"141.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"192.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.8","Single Cell Type RNA - Paneth cells [nTPM]":"34.9","Single Cell Type RNA - Peritubular cells [nTPM]":"35.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.4","Single Cell Type RNA - Spermatocytes [nTPM]":"55.6","Single Cell Type RNA - Spermatogonia [nTPM]":"41.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"76.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.6","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"35.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"37.6"}]