[{"Gene":"ADCK1","Gene synonym":["FLJ39600"],"Ensembl":"ENSG00000063761","Gene description":"AarF domain containing kinase 1","Uniprot":["Q86TW2"],"Chromosome":"14","Position":"77800109-77935014","Protein class":["Enzymes","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"20.9","Oligodendrocytes":"29.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051012","HPA055014"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051012":"AB_2681310","HPA055014":"AB_2682672"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.11e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.82e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"5.3","Tissue RNA - breast [nTPM]":"4.2","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"10.3","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"4.8","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"8.9","Tissue RNA - skin 1 [nTPM]":"6.3","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"6.4","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"7.3","Tissue RNA - stomach 1 [nTPM]":"6.1","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"5.1","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"10.2","Cell RNA - A-431 [nTPM]":"5.5","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"6.5","Cell RNA - BEWO [nTPM]":"6.2","Cell RNA - BJ [nTPM]":"5.7","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.6","Cell RNA - CACO-2 [nTPM]":"4.7","Cell RNA - CAPAN-2 [nTPM]":"12.4","Cell RNA - Daudi [nTPM]":"12.0","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"27.0","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"6.3","Cell RNA - HEK 293 [nTPM]":"9.1","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"12.2","Cell RNA - HL-60 [nTPM]":"4.5","Cell RNA - HMC-1 [nTPM]":"6.6","Cell RNA - HSkMC [nTPM]":"7.7","Cell RNA - hTCEpi [nTPM]":"16.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.9","Cell RNA - hTERT-HME1 [nTPM]":"5.7","Cell RNA - hTERT-RPE1 [nTPM]":"4.4","Cell RNA - HUVEC TERT2 [nTPM]":"7.1","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"11.4","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"5.9","Cell RNA - MCF7 [nTPM]":"24.5","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"7.6","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"9.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.6","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"10.4","Cell RNA - SH-SY5Y [nTPM]":"6.0","Cell RNA - SiHa [nTPM]":"10.6","Cell RNA - SK-BR-3 [nTPM]":"14.7","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"20.9","Cell RNA - THP-1 [nTPM]":"9.4","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"4.6","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"6.0","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"7.4","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"10.3","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"10.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"2.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"ADCK2","Gene synonym":["MGC20727"],"Ensembl":"ENSG00000133597","Gene description":"AarF domain containing kinase 2","Uniprot":["Q7Z695"],"Chromosome":"7","Position":"140672945-140696261","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"98.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036036":"AB_10672078"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.4","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"23.7","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"25.1","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"25.9","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"16.5","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"17.5","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"10.7","Tissue RNA - hippocampal formation [nTPM]":"24.3","Tissue RNA - hypothalamus [nTPM]":"24.2","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"14.8","Tissue RNA - medulla oblongata [nTPM]":"29.1","Tissue RNA - midbrain [nTPM]":"25.6","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"19.5","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"25.9","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"10.7","Tissue RNA - skeletal muscle [nTPM]":"14.1","Tissue RNA - skin 1 [nTPM]":"26.3","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"9.0","Tissue RNA - spinal cord [nTPM]":"26.3","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"13.1","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"26.4","Tissue RNA - thymus [nTPM]":"12.4","Tissue RNA - thyroid gland [nTPM]":"12.8","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"14.1","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"30.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"23.2","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"19.3","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"31.7","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"20.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.2","Cell RNA - CACO-2 [nTPM]":"21.7","Cell RNA - CAPAN-2 [nTPM]":"22.5","Cell RNA - Daudi [nTPM]":"42.4","Cell RNA - EFO-21 [nTPM]":"24.0","Cell RNA - fHDF\/TERT166 [nTPM]":"11.7","Cell RNA - GAMG [nTPM]":"39.4","Cell RNA - HaCaT [nTPM]":"26.3","Cell RNA - HAP1 [nTPM]":"27.5","Cell RNA - HBEC3-KT [nTPM]":"19.0","Cell RNA - HBF TERT88 [nTPM]":"5.1","Cell RNA - HDLM-2 [nTPM]":"31.3","Cell RNA - HEK 293 [nTPM]":"26.1","Cell RNA - HEL [nTPM]":"9.2","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"11.1","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"21.8","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"56.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"13.5","Cell RNA - hTERT-RPE1 [nTPM]":"17.3","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"30.9","Cell RNA - K-562 [nTPM]":"16.1","Cell RNA - Karpas-707 [nTPM]":"20.9","Cell RNA - LHCN-M2 [nTPM]":"6.1","Cell RNA - MCF7 [nTPM]":"41.0","Cell RNA - MOLT-4 [nTPM]":"46.4","Cell RNA - NB-4 [nTPM]":"15.3","Cell RNA - NTERA-2 [nTPM]":"8.2","Cell RNA - OE19 [nTPM]":"27.0","Cell RNA - PC-3 [nTPM]":"23.1","Cell RNA - REH [nTPM]":"36.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"21.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"34.9","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"22.7","Cell RNA - SK-BR-3 [nTPM]":"32.7","Cell RNA - SK-MEL-30 [nTPM]":"23.3","Cell RNA - SuSa [nTPM]":"10.1","Cell RNA - T-47d [nTPM]":"29.2","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"21.3","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"35.0","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"23.2","Cell RNA - U-698 [nTPM]":"32.4","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"23.9","Cell RNA - WM-115 [nTPM]":"25.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.4","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"23.7","Brain RNA - basal ganglia [nTPM]":"25.1","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"25.9","Brain RNA - hippocampal formation [nTPM]":"24.3","Brain RNA - hypothalamus [nTPM]":"24.2","Brain RNA - medulla oblongata [nTPM]":"29.1","Brain RNA - midbrain [nTPM]":"25.6","Brain RNA - pons [nTPM]":"25.9","Brain RNA - spinal cord [nTPM]":"26.3","Brain RNA - thalamus [nTPM]":"26.4","Brain RNA - white matter [nTPM]":"30.2","Single Cell Type RNA - Adipocytes [nTPM]":"9.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"9.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.9","Single Cell Type RNA - dendritic cells [nTPM]":"17.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"37.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"98.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.4","Single Cell Type RNA - Langerhans cells [nTPM]":"16.1","Single Cell Type RNA - Late spermatids [nTPM]":"16.4","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"14.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"5.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"9.6","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"21.2"},{"Gene":"ADCK5","Gene synonym":["FLJ35454"],"Ensembl":"ENSG00000173137","Gene description":"AarF domain containing kinase 5","Uniprot":["Q3MIX3"],"Chromosome":"8","Position":"144373101-144393242","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"61.7","Theca cells":"42.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025692","HPA028679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA025692":"AB_10599486","HPA028679":"AB_10600226"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.1","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"3.7","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"3.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.8","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"2.9","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"0.9","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"2.3","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"2.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"3.1","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"2.2","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"3.2","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"6.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"16.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.3","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"5.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.1","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"42.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"ALPK1","Gene synonym":["FLJ22670","KIAA1527","Lak"],"Ensembl":"ENSG00000073331","Gene description":"Alpha kinase 1","Uniprot":["Q96QP1"],"Chromosome":"4","Position":"112285509-112442621","Protein class":["Enzymes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"73.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"18.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027435","HPA027443"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA027435":"AB_10599614","HPA027443":"AB_10599421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"5.4","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"8.7","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"6.0","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"10.1","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"1.7","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"7.8","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"5.2","Cell RNA - HaCaT [nTPM]":"1.0","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"2.0","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"8.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.7","Cell RNA - hTERT-HME1 [nTPM]":"7.8","Cell RNA - hTERT-RPE1 [nTPM]":"5.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"5.0","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"3.7","Cell RNA - PC-3 [nTPM]":"1.2","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.9","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"4.1","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"5.8","Cell RNA - U-937 [nTPM]":"5.3","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"1.6","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"18.7","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"7.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"18.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"16.1","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.1","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"7.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.4"},{"Gene":"ALPK2","Gene synonym":["HAK"],"Ensembl":"ENSG00000198796","Gene description":"Alpha kinase 2","Uniprot":["Q86TB3"],"Chromosome":"18","Position":"58481247-58629091","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"41.9","skeletal muscle":"38.3","tongue":"33.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"120.4","Cone photoreceptor cells":"47.9","Early spermatids":"15.9","Late spermatids":"24.3","monocytes":"18.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"renal cancer":"7.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"51.2","BJ hTERT+":"31.0","fHDF\/TERT166":"46.6","U-138 MG":"25.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027377","HPA027976","HPA028084","HPA029801"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027377":"AB_10600635","HPA027976":"AB_10611246","HPA028084":"AB_10601996","HPA029801":"AB_10602006"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"2.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"41.9","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"38.3","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"33.2","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"13.7","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"3.4","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"51.2","Cell RNA - BJ hTERT+ [nTPM]":"31.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.1","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"46.6","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"21.5","Cell RNA - HDLM-2 [nTPM]":"11.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"13.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"11.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"8.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"25.3","Cell RNA - U-2 OS [nTPM]":"11.2","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"8.7","Cell RNA - U-266\/70 [nTPM]":"20.9","Cell RNA - U-266\/84 [nTPM]":"19.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"120.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"24.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"ALPK3","Gene synonym":["KIAA1330","MAK","Midori"],"Ensembl":"ENSG00000136383","Gene description":"Alpha kinase 3","Uniprot":["Q96L96"],"Chromosome":"15","Position":"84817356-84873479","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"62.7","skeletal muscle":"195.8","tongue":"59.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"64.1","Exocrine glandular cells":"20.5","Skeletal myocytes":"51.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"14.3","HDLM-2":"10.7","HUVEC TERT2":"15.5","LHCN-M2":"21.2","NTERA-2":"12.9","RH-30":"37.7","THP-1":"9.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026558"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026558":"AB_1844774"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.9","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"9.3","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"62.7","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"3.8","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"5.9","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"11.2","Tissue RNA - pituitary gland [nTPM]":"26.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"195.8","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"3.6","Tissue RNA - tongue [nTPM]":"59.1","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"21.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"37.7","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"3.8","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"64.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"12.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.6"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"ATR","Gene synonym":["FRP1","MEC1","SCKL","SCKL1"],"Ensembl":"ENSG00000175054","Gene description":"ATR serine\/threonine kinase","Uniprot":["Q13535"],"Chromosome":"3","Position":"142449007-142578733","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.0","Inhibitory neurons":"94.4","Microglial cells":"73.1","Oligodendrocyte precursor cells":"65.4","Oligodendrocytes":"71.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054320"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054320":"AB_2682448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"7.0","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.7","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.1","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"10.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"8.2","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"BCKDK","Gene synonym":[],"Ensembl":"ENSG00000103507","Gene description":"Branched chain keto acid dehydrogenase kinase","Uniprot":["O14874"],"Chromosome":"16","Position":"31106107-31112791","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Epilepsy","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"95.9","granulocytes":"89.7","monocytes":"115.0"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017995","HPA056067"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017995":"AB_1845309","HPA056067":"AB_2683024"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.3","Tissue RNA - adrenal gland [nTPM]":"56.4","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"18.6","Tissue RNA - bone marrow [nTPM]":"14.5","Tissue RNA - breast [nTPM]":"29.0","Tissue RNA - cerebellum [nTPM]":"17.4","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"31.4","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"29.4","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"17.9","Tissue RNA - heart muscle [nTPM]":"78.6","Tissue RNA - hippocampal formation [nTPM]":"18.8","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"43.8","Tissue RNA - liver [nTPM]":"76.4","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"20.7","Tissue RNA - ovary [nTPM]":"27.5","Tissue RNA - pancreas [nTPM]":"70.5","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"16.4","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"19.3","Tissue RNA - prostate [nTPM]":"29.3","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"47.0","Tissue RNA - seminal vesicle [nTPM]":"21.8","Tissue RNA - skeletal muscle [nTPM]":"81.3","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"17.1","Tissue RNA - spleen [nTPM]":"30.2","Tissue RNA - stomach 1 [nTPM]":"42.0","Tissue RNA - testis [nTPM]":"17.4","Tissue RNA - thalamus [nTPM]":"18.5","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"69.7","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"30.2","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"47.5","Cell RNA - A549 [nTPM]":"49.1","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"41.8","Cell RNA - ASC diff [nTPM]":"32.8","Cell RNA - ASC TERT1 [nTPM]":"32.5","Cell RNA - BEWO [nTPM]":"31.1","Cell RNA - BJ [nTPM]":"40.4","Cell RNA - BJ hTERT+ [nTPM]":"46.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.9","Cell RNA - CACO-2 [nTPM]":"32.1","Cell RNA - CAPAN-2 [nTPM]":"29.1","Cell RNA - Daudi [nTPM]":"41.5","Cell RNA - EFO-21 [nTPM]":"58.9","Cell RNA - fHDF\/TERT166 [nTPM]":"47.5","Cell RNA - GAMG [nTPM]":"28.0","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"19.3","Cell RNA - HBEC3-KT [nTPM]":"65.6","Cell RNA - HBF TERT88 [nTPM]":"36.5","Cell RNA - HDLM-2 [nTPM]":"34.4","Cell RNA - HEK 293 [nTPM]":"60.1","Cell RNA - HEL [nTPM]":"45.2","Cell RNA - HeLa [nTPM]":"32.6","Cell RNA - Hep G2 [nTPM]":"59.5","Cell RNA - HHSteC [nTPM]":"57.5","Cell RNA - HL-60 [nTPM]":"23.5","Cell RNA - HMC-1 [nTPM]":"41.9","Cell RNA - HSkMC [nTPM]":"48.3","Cell RNA - hTCEpi [nTPM]":"26.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.2","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"52.6","Cell RNA - HUVEC TERT2 [nTPM]":"62.4","Cell RNA - JURKAT [nTPM]":"31.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"39.4","Cell RNA - LHCN-M2 [nTPM]":"87.7","Cell RNA - MCF7 [nTPM]":"75.8","Cell RNA - MOLT-4 [nTPM]":"22.9","Cell RNA - NB-4 [nTPM]":"32.4","Cell RNA - NTERA-2 [nTPM]":"23.0","Cell RNA - OE19 [nTPM]":"20.5","Cell RNA - PC-3 [nTPM]":"39.1","Cell RNA - REH [nTPM]":"45.8","Cell RNA - RH-30 [nTPM]":"39.6","Cell RNA - RPMI-8226 [nTPM]":"78.8","Cell RNA - RPTEC TERT1 [nTPM]":"44.3","Cell RNA - RT4 [nTPM]":"30.1","Cell RNA - SCLC-21H [nTPM]":"42.1","Cell RNA - SH-SY5Y [nTPM]":"38.7","Cell RNA - SiHa [nTPM]":"31.3","Cell RNA - SK-BR-3 [nTPM]":"72.4","Cell RNA - SK-MEL-30 [nTPM]":"24.6","Cell RNA - SuSa [nTPM]":"22.9","Cell RNA - T-47d [nTPM]":"44.5","Cell RNA - THP-1 [nTPM]":"24.6","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"44.2","Cell RNA - U-2 OS [nTPM]":"26.1","Cell RNA - U-2197 [nTPM]":"45.8","Cell RNA - U-251 MG [nTPM]":"32.2","Cell RNA - U-266\/70 [nTPM]":"44.5","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"15.1","Cell RNA - U-87 MG [nTPM]":"50.3","Cell RNA - U-937 [nTPM]":"33.7","Cell RNA - WM-115 [nTPM]":"42.6","Blood RNA - basophil [nTPM]":"58.1","Blood RNA - classical monocyte [nTPM]":"115.0","Blood RNA - eosinophil [nTPM]":"85.2","Blood RNA - gdT-cell [nTPM]":"17.7","Blood RNA - intermediate monocyte [nTPM]":"97.6","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"22.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.5","Blood RNA - memory CD8 T-cell [nTPM]":"13.9","Blood RNA - myeloid DC [nTPM]":"95.9","Blood RNA - naive B-cell [nTPM]":"19.0","Blood RNA - naive CD4 T-cell [nTPM]":"13.6","Blood RNA - naive CD8 T-cell [nTPM]":"16.1","Blood RNA - neutrophil [nTPM]":"89.7","Blood RNA - NK-cell [nTPM]":"22.8","Blood RNA - non-classical monocyte [nTPM]":"71.2","Blood RNA - plasmacytoid DC [nTPM]":"19.3","Blood RNA - T-reg [nTPM]":"24.5","Blood RNA - total PBMC [nTPM]":"53.1","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"18.6","Brain RNA - cerebellum [nTPM]":"17.4","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"18.8","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"20.7","Brain RNA - pons [nTPM]":"19.3","Brain RNA - spinal cord [nTPM]":"17.1","Brain RNA - thalamus [nTPM]":"18.5","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"27.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"20.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"55.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"68.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.3","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.1","Single Cell Type RNA - Fibroblasts [nTPM]":"24.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.0","Single Cell Type RNA - granulocytes [nTPM]":"33.0","Single Cell Type RNA - Granulosa cells [nTPM]":"35.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"43.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"93.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.3","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"44.5","Single Cell Type RNA - Langerhans cells [nTPM]":"50.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"53.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"79.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.8","Single Cell Type RNA - Paneth cells [nTPM]":"48.4","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"51.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"95.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.2","Single Cell Type RNA - Spermatocytes [nTPM]":"25.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.4","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"45.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.0"},{"Gene":"COQ8A","Gene synonym":["ADCK3","CABC1","COQ8","SCAR9"],"Ensembl":"ENSG00000163050","Gene description":"Coenzyme Q8A","Uniprot":["Q8NI60"],"Chromosome":"1","Position":"226940286-226987544","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skeletal muscle":"1165.1","tongue":"484.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"21.9","Collecting duct cells":"33.1","Ductal cells":"21.2","Exocrine glandular cells":"32.7","Proximal tubular cells":"24.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"82.0","RPMI-8226":"78.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061662"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA061662":"AB_2684578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"63.9","Tissue RNA - adrenal gland [nTPM]":"123.8","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"26.1","Tissue RNA - breast [nTPM]":"35.8","Tissue RNA - cerebellum [nTPM]":"17.3","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"16.5","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"30.8","Tissue RNA - duodenum [nTPM]":"29.9","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"32.2","Tissue RNA - fallopian tube [nTPM]":"24.6","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"123.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"35.7","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"34.1","Tissue RNA - pancreas [nTPM]":"93.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"18.5","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"32.7","Tissue RNA - seminal vesicle [nTPM]":"11.7","Tissue RNA - skeletal muscle [nTPM]":"1165.1","Tissue RNA - skin 1 [nTPM]":"25.1","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"52.8","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"484.7","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"40.8","Tissue RNA - vagina [nTPM]":"13.4","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"8.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"3.3","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"11.4","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"57.7","Cell RNA - BJ [nTPM]":"3.6","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"23.0","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"17.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"2.6","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"8.2","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"25.5","Cell RNA - HEK 293 [nTPM]":"82.0","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"11.2","Cell RNA - Hep G2 [nTPM]":"38.8","Cell RNA - HHSteC [nTPM]":"2.5","Cell RNA - HL-60 [nTPM]":"25.8","Cell RNA - HMC-1 [nTPM]":"9.3","Cell RNA - HSkMC [nTPM]":"14.2","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.5","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"19.4","Cell RNA - LHCN-M2 [nTPM]":"0.7","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"37.3","Cell RNA - NTERA-2 [nTPM]":"15.5","Cell RNA - OE19 [nTPM]":"62.8","Cell RNA - PC-3 [nTPM]":"29.5","Cell RNA - REH [nTPM]":"14.9","Cell RNA - RH-30 [nTPM]":"17.1","Cell RNA - RPMI-8226 [nTPM]":"78.6","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"59.9","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"7.3","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"3.4","Cell RNA - T-47d [nTPM]":"15.1","Cell RNA - THP-1 [nTPM]":"34.8","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"8.2","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"43.0","Cell RNA - U-266\/84 [nTPM]":"40.5","Cell RNA - U-698 [nTPM]":"13.1","Cell RNA - U-87 MG [nTPM]":"5.3","Cell RNA - U-937 [nTPM]":"29.3","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"47.7","Blood RNA - classical monocyte [nTPM]":"23.5","Blood RNA - eosinophil [nTPM]":"68.4","Blood RNA - gdT-cell [nTPM]":"15.8","Blood RNA - intermediate monocyte [nTPM]":"17.1","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"22.2","Blood RNA - memory CD4 T-cell [nTPM]":"15.8","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"26.8","Blood RNA - naive CD4 T-cell [nTPM]":"21.5","Blood RNA - naive CD8 T-cell [nTPM]":"17.0","Blood RNA - neutrophil [nTPM]":"43.1","Blood RNA - NK-cell [nTPM]":"21.2","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"21.5","Blood RNA - total PBMC [nTPM]":"26.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"17.3","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"21.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.6","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COQ8B","Gene synonym":["ADCK4","COQ8","FLJ12229"],"Ensembl":"ENSG00000123815","Gene description":"Coenzyme Q8B","Uniprot":["Q96D53"],"Chromosome":"19","Position":"40691514-40725784","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"16.5","Endometrial ciliated cells":"16.4","Theca cells":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027229","HPA027277","HPA027279","HPA028303"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027229":"AB_10600100","HPA027277":"AB_10599857","HPA027279":"AB_10601219","HPA028303":"AB_2672551"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"25.2","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"15.3","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"19.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"22.0","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"29.8","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"21.9","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"21.0","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"22.5","Tissue RNA - pancreas [nTPM]":"20.7","Tissue RNA - parathyroid gland [nTPM]":"8.4","Tissue RNA - pituitary gland [nTPM]":"49.3","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"10.3","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"20.2","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"11.2","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"17.3","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"20.3","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"10.5","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"39.5","Cell RNA - AF22 [nTPM]":"7.9","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"6.1","Cell RNA - BEWO [nTPM]":"8.5","Cell RNA - BJ [nTPM]":"6.6","Cell RNA - BJ hTERT+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"14.3","Cell RNA - Daudi [nTPM]":"13.8","Cell RNA - EFO-21 [nTPM]":"20.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"9.8","Cell RNA - HAP1 [nTPM]":"7.0","Cell RNA - HBEC3-KT [nTPM]":"10.5","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"20.0","Cell RNA - HEK 293 [nTPM]":"10.4","Cell RNA - HEL [nTPM]":"11.6","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"12.1","Cell RNA - HL-60 [nTPM]":"4.1","Cell RNA - HMC-1 [nTPM]":"19.2","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.2","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"8.1","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"6.4","Cell RNA - MOLT-4 [nTPM]":"4.9","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"6.4","Cell RNA - OE19 [nTPM]":"11.5","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"11.5","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"12.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"17.6","Cell RNA - SCLC-21H [nTPM]":"15.1","Cell RNA - SH-SY5Y [nTPM]":"11.0","Cell RNA - SiHa [nTPM]":"12.5","Cell RNA - SK-BR-3 [nTPM]":"20.4","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"17.1","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"20.6","Cell RNA - U-2197 [nTPM]":"3.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"7.3","Cell RNA - U-87 MG [nTPM]":"27.8","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"9.1","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"6.7","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"7.1","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"7.8","Blood RNA - myeloid DC [nTPM]":"9.9","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"9.0","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"4.9","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"10.3","Brain RNA - spinal cord [nTPM]":"11.2","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"10.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"3.2","Single Cell Type RNA - Theca cells [nTPM]":"19.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"EEF2K","Gene synonym":["CaMKIII","eEF-2K"],"Ensembl":"ENSG00000103319","Gene description":"Eukaryotic elongation factor 2 kinase","Uniprot":["O00418"],"Chromosome":"16","Position":"22206278-22288738","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"49.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"69.1","Late spermatids":"76.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"1.5","HL-60":"1.6","HMC-1":"1.8","NB-4":"1.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007818","HPA056061"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB007818":"AB_598150","HPA056061":"AB_2683021"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"7.1","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"9.2","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"9.0","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"12.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"19.6","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"24.9","Tissue RNA - skin 1 [nTPM]":"49.0","Tissue RNA - small intestine [nTPM]":"8.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"6.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"1.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"43.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.3","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"7.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"69.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"42.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.9","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.5","Single Cell Type RNA - Hepatocytes [nTPM]":"17.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.3","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"76.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.2","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"19.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"7.8","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"FASTK","Gene synonym":["FAST"],"Ensembl":"ENSG00000164896","Gene description":"Fas activated serine\/threonine kinase","Uniprot":["Q14296"],"Chromosome":"7","Position":"151076593-151080866","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","RNA-binding","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031621","CAB032539"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"CAB032539":"AB_2101115","HPA031621":"AB_10611966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.4","Tissue RNA - adrenal gland [nTPM]":"36.5","Tissue RNA - amygdala [nTPM]":"35.5","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"33.8","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"32.3","Tissue RNA - cerebral cortex [nTPM]":"50.6","Tissue RNA - cervix [nTPM]":"23.5","Tissue RNA - choroid plexus [nTPM]":"30.1","Tissue RNA - colon [nTPM]":"31.5","Tissue RNA - duodenum [nTPM]":"26.2","Tissue RNA - endometrium 1 [nTPM]":"23.3","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"39.5","Tissue RNA - fallopian tube [nTPM]":"21.1","Tissue RNA - gallbladder [nTPM]":"14.5","Tissue RNA - heart muscle [nTPM]":"66.9","Tissue RNA - hippocampal formation [nTPM]":"34.8","Tissue RNA - hypothalamus [nTPM]":"32.9","Tissue RNA - kidney [nTPM]":"34.9","Tissue RNA - liver [nTPM]":"58.0","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"14.4","Tissue RNA - medulla oblongata [nTPM]":"34.2","Tissue RNA - midbrain [nTPM]":"33.9","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"28.1","Tissue RNA - parathyroid gland [nTPM]":"31.0","Tissue RNA - pituitary gland [nTPM]":"41.2","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"34.5","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"11.8","Tissue RNA - retina [nTPM]":"7.9","Tissue RNA - salivary gland [nTPM]":"27.8","Tissue RNA - seminal vesicle [nTPM]":"18.8","Tissue RNA - skeletal muscle [nTPM]":"122.6","Tissue RNA - skin 1 [nTPM]":"28.2","Tissue RNA - small intestine [nTPM]":"25.0","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"33.1","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"29.0","Tissue RNA - testis [nTPM]":"21.8","Tissue RNA - thalamus [nTPM]":"35.7","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"26.9","Tissue RNA - tongue [nTPM]":"95.3","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"26.7","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"34.3","Cell RNA - A-431 [nTPM]":"39.3","Cell RNA - A549 [nTPM]":"45.0","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"34.9","Cell RNA - ASC diff [nTPM]":"50.4","Cell RNA - ASC TERT1 [nTPM]":"22.4","Cell RNA - BEWO [nTPM]":"22.8","Cell RNA - BJ [nTPM]":"29.9","Cell RNA - BJ hTERT+ [nTPM]":"40.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.7","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"34.9","Cell RNA - Daudi [nTPM]":"9.2","Cell RNA - EFO-21 [nTPM]":"41.0","Cell RNA - fHDF\/TERT166 [nTPM]":"40.9","Cell RNA - GAMG [nTPM]":"46.9","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"36.4","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"26.9","Cell RNA - HEK 293 [nTPM]":"23.8","Cell RNA - HEL [nTPM]":"11.4","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"27.8","Cell RNA - HHSteC [nTPM]":"62.7","Cell RNA - HL-60 [nTPM]":"9.0","Cell RNA - HMC-1 [nTPM]":"25.2","Cell RNA - HSkMC [nTPM]":"29.8","Cell RNA - hTCEpi [nTPM]":"51.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.4","Cell RNA - hTERT-HME1 [nTPM]":"21.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.9","Cell RNA - HUVEC TERT2 [nTPM]":"30.0","Cell RNA - JURKAT [nTPM]":"22.4","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"20.2","Cell RNA - LHCN-M2 [nTPM]":"29.2","Cell RNA - MCF7 [nTPM]":"80.4","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"23.5","Cell RNA - NTERA-2 [nTPM]":"24.6","Cell RNA - OE19 [nTPM]":"47.8","Cell RNA - PC-3 [nTPM]":"50.8","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"17.4","Cell RNA - RPMI-8226 [nTPM]":"30.4","Cell RNA - RPTEC TERT1 [nTPM]":"34.2","Cell RNA - RT4 [nTPM]":"27.8","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"40.3","Cell RNA - SK-BR-3 [nTPM]":"62.5","Cell RNA - SK-MEL-30 [nTPM]":"43.0","Cell RNA - SuSa [nTPM]":"11.5","Cell RNA - T-47d [nTPM]":"34.4","Cell RNA - THP-1 [nTPM]":"31.2","Cell RNA - TIME [nTPM]":"24.0","Cell RNA - U-138 MG [nTPM]":"32.7","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"31.7","Cell RNA - U-251 MG [nTPM]":"28.0","Cell RNA - U-266\/70 [nTPM]":"50.5","Cell RNA - U-266\/84 [nTPM]":"33.0","Cell RNA - U-698 [nTPM]":"6.5","Cell RNA - U-87 MG [nTPM]":"66.2","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"39.8","Blood RNA - basophil [nTPM]":"18.0","Blood RNA - classical monocyte [nTPM]":"31.5","Blood RNA - eosinophil [nTPM]":"30.1","Blood RNA - gdT-cell [nTPM]":"22.3","Blood RNA - intermediate monocyte [nTPM]":"32.5","Blood RNA - MAIT T-cell [nTPM]":"23.4","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"23.4","Blood RNA - memory CD8 T-cell [nTPM]":"23.4","Blood RNA - myeloid DC [nTPM]":"28.4","Blood RNA - naive B-cell [nTPM]":"21.6","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"21.9","Blood RNA - neutrophil [nTPM]":"6.8","Blood RNA - NK-cell [nTPM]":"20.4","Blood RNA - non-classical monocyte [nTPM]":"32.5","Blood RNA - plasmacytoid DC [nTPM]":"38.2","Blood RNA - T-reg [nTPM]":"28.3","Blood RNA - total PBMC [nTPM]":"21.9","Brain RNA - amygdala [nTPM]":"35.5","Brain RNA - basal ganglia [nTPM]":"33.8","Brain RNA - cerebellum [nTPM]":"32.3","Brain RNA - cerebral cortex [nTPM]":"50.6","Brain RNA - hippocampal formation [nTPM]":"34.8","Brain RNA - hypothalamus [nTPM]":"32.9","Brain RNA - medulla oblongata [nTPM]":"34.2","Brain RNA - midbrain [nTPM]":"33.9","Brain RNA - pons [nTPM]":"34.5","Brain RNA - spinal cord [nTPM]":"33.1","Brain RNA - thalamus [nTPM]":"35.7","Brain RNA - white matter [nTPM]":"34.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"34.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"68.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"42.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"43.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.2","Single Cell Type RNA - dendritic cells [nTPM]":"38.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"86.1","Single Cell Type RNA - Ductal cells [nTPM]":"49.4","Single Cell Type RNA - Early spermatids [nTPM]":"10.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.3","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.9","Single Cell Type RNA - Erythroid cells [nTPM]":"28.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"47.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.8","Single Cell Type RNA - Fibroblasts [nTPM]":"33.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"38.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"37.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.3","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.9","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.3","Single Cell Type RNA - Langerhans cells [nTPM]":"22.5","Single Cell Type RNA - Late spermatids [nTPM]":"20.2","Single Cell Type RNA - Leydig cells [nTPM]":"36.4","Single Cell Type RNA - Macrophages [nTPM]":"25.8","Single Cell Type RNA - Melanocytes [nTPM]":"94.3","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"35.3","Single Cell Type RNA - Muller glia cells [nTPM]":"54.7","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.6","Single Cell Type RNA - Paneth cells [nTPM]":"40.0","Single Cell Type RNA - Peritubular cells [nTPM]":"34.3","Single Cell Type RNA - Plasma cells [nTPM]":"46.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"86.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.5","Single Cell Type RNA - Spermatogonia [nTPM]":"70.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.5","Single Cell Type RNA - T-cells [nTPM]":"34.8","Single Cell Type RNA - Theca cells [nTPM]":"50.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"61.2","Single Cell Type RNA - Urothelial cells [nTPM]":"35.0"},{"Gene":"MTOR","Gene synonym":["FLJ44809","FRAP","FRAP1","FRAP2","RAFT1","RAPT1"],"Ensembl":"ENSG00000198793","Gene description":"Mechanistic target of rapamycin kinase","Uniprot":["P42345"],"Chromosome":"1","Position":"11106535-11262551","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB069425","HPA071227"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB069425":null,"HPA071227":"AB_2686367"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.3","Tissue RNA - adrenal gland [nTPM]":"19.4","Tissue RNA - amygdala [nTPM]":"18.2","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"19.0","Tissue RNA - bone marrow [nTPM]":"14.0","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"18.4","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"18.6","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"17.5","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"23.6","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"17.7","Tissue RNA - kidney [nTPM]":"24.1","Tissue RNA - liver [nTPM]":"27.6","Tissue RNA - lung [nTPM]":"15.2","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"16.5","Tissue RNA - midbrain [nTPM]":"21.2","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"20.6","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"18.4","Tissue RNA - prostate [nTPM]":"19.8","Tissue RNA - rectum [nTPM]":"16.0","Tissue RNA - retina [nTPM]":"26.9","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"13.8","Tissue RNA - skeletal muscle [nTPM]":"36.4","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"19.6","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"21.2","Tissue RNA - stomach 1 [nTPM]":"18.7","Tissue RNA - testis [nTPM]":"33.8","Tissue RNA - thalamus [nTPM]":"22.7","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"17.8","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"17.1","Tissue RNA - vagina [nTPM]":"14.9","Tissue RNA - white matter [nTPM]":"18.7","Cell RNA - A-431 [nTPM]":"28.5","Cell RNA - A549 [nTPM]":"25.2","Cell RNA - AF22 [nTPM]":"33.3","Cell RNA - AN3-CA [nTPM]":"25.4","Cell RNA - ASC diff [nTPM]":"39.4","Cell RNA - ASC TERT1 [nTPM]":"18.6","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"23.4","Cell RNA - BJ hTERT+ [nTPM]":"22.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.9","Cell RNA - CACO-2 [nTPM]":"26.0","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"31.4","Cell RNA - EFO-21 [nTPM]":"19.6","Cell RNA - fHDF\/TERT166 [nTPM]":"27.8","Cell RNA - GAMG [nTPM]":"18.8","Cell RNA - HaCaT [nTPM]":"33.1","Cell RNA - HAP1 [nTPM]":"45.3","Cell RNA - HBEC3-KT [nTPM]":"35.8","Cell RNA - HBF TERT88 [nTPM]":"39.3","Cell RNA - HDLM-2 [nTPM]":"25.2","Cell RNA - HEK 293 [nTPM]":"33.2","Cell RNA - HEL [nTPM]":"41.7","Cell RNA - HeLa [nTPM]":"53.8","Cell RNA - Hep G2 [nTPM]":"33.4","Cell RNA - HHSteC [nTPM]":"24.7","Cell RNA - HL-60 [nTPM]":"41.1","Cell RNA - HMC-1 [nTPM]":"29.7","Cell RNA - HSkMC [nTPM]":"24.0","Cell RNA - hTCEpi [nTPM]":"26.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"44.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.5","Cell RNA - HUVEC TERT2 [nTPM]":"39.3","Cell RNA - JURKAT [nTPM]":"29.6","Cell RNA - K-562 [nTPM]":"47.4","Cell RNA - Karpas-707 [nTPM]":"26.1","Cell RNA - LHCN-M2 [nTPM]":"21.6","Cell RNA - MCF7 [nTPM]":"32.4","Cell RNA - MOLT-4 [nTPM]":"28.5","Cell RNA - NB-4 [nTPM]":"31.2","Cell RNA - NTERA-2 [nTPM]":"25.3","Cell RNA - OE19 [nTPM]":"29.6","Cell RNA - PC-3 [nTPM]":"23.5","Cell RNA - REH [nTPM]":"28.2","Cell RNA - RH-30 [nTPM]":"39.2","Cell RNA - RPMI-8226 [nTPM]":"21.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"25.3","Cell RNA - SCLC-21H [nTPM]":"33.4","Cell RNA - SH-SY5Y [nTPM]":"24.5","Cell RNA - SiHa [nTPM]":"50.1","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"31.2","Cell RNA - SuSa [nTPM]":"36.5","Cell RNA - T-47d [nTPM]":"21.8","Cell RNA - THP-1 [nTPM]":"24.0","Cell RNA - TIME [nTPM]":"42.3","Cell RNA - U-138 MG [nTPM]":"26.5","Cell RNA - U-2 OS [nTPM]":"23.9","Cell RNA - U-2197 [nTPM]":"20.5","Cell RNA - U-251 MG [nTPM]":"31.8","Cell RNA - U-266\/70 [nTPM]":"25.5","Cell RNA - U-266\/84 [nTPM]":"25.5","Cell RNA - U-698 [nTPM]":"60.5","Cell RNA - U-87 MG [nTPM]":"19.1","Cell RNA - U-937 [nTPM]":"43.6","Cell RNA - WM-115 [nTPM]":"28.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"18.2","Brain RNA - basal ganglia [nTPM]":"19.0","Brain RNA - cerebellum [nTPM]":"18.4","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"17.7","Brain RNA - medulla oblongata [nTPM]":"16.5","Brain RNA - midbrain [nTPM]":"21.2","Brain RNA - pons [nTPM]":"18.4","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"22.7","Brain RNA - white matter [nTPM]":"18.7","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.8","Single Cell Type RNA - B-cells [nTPM]":"10.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"42.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.3","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"13.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"49.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.1","Single Cell Type RNA - Late spermatids [nTPM]":"36.1","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"9.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"9.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"8.2","Single Cell Type RNA - Plasma cells [nTPM]":"17.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.1","Single Cell Type RNA - Spermatocytes [nTPM]":"49.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"9.8","Single Cell Type RNA - Theca cells [nTPM]":"15.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.7"},{"Gene":"PDK1","Gene synonym":[],"Ensembl":"ENSG00000152256","Gene description":"Pyruvate dehydrogenase kinase 1","Uniprot":["Q15118"],"Chromosome":"2","Position":"172555373-172608669","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"130.4","Plasma cells":"144.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"8.6","granulocytes":"25.2","T-cells":"21.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"71.8","U-87 MG":"72.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017554","HPA027376"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017554":"AB_2161138","HPA027376":"AB_1855139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"16.0","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"11.6","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"15.8","Tissue RNA - breast [nTPM]":"10.1","Tissue RNA - cerebellum [nTPM]":"5.6","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"16.5","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"8.5","Tissue RNA - fallopian tube [nTPM]":"3.6","Tissue RNA - gallbladder [nTPM]":"6.0","Tissue RNA - heart muscle [nTPM]":"28.1","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"13.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"12.2","Tissue RNA - pancreas [nTPM]":"6.9","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"27.1","Tissue RNA - salivary gland [nTPM]":"10.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"18.1","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"5.0","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"19.1","Tissue RNA - urinary bladder [nTPM]":"11.0","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"34.0","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"21.0","Cell RNA - ASC diff [nTPM]":"3.4","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"12.1","Cell RNA - BJ [nTPM]":"29.1","Cell RNA - BJ hTERT+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.4","Cell RNA - CACO-2 [nTPM]":"8.6","Cell RNA - CAPAN-2 [nTPM]":"7.1","Cell RNA - Daudi [nTPM]":"32.1","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"9.1","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"14.5","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"18.2","Cell RNA - HBF TERT88 [nTPM]":"45.5","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"11.7","Cell RNA - HEL [nTPM]":"39.3","Cell RNA - HeLa [nTPM]":"7.1","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"19.6","Cell RNA - HMC-1 [nTPM]":"14.0","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"16.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"16.7","Cell RNA - K-562 [nTPM]":"8.5","Cell RNA - Karpas-707 [nTPM]":"21.5","Cell RNA - LHCN-M2 [nTPM]":"19.2","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"12.5","Cell RNA - NB-4 [nTPM]":"24.5","Cell RNA - NTERA-2 [nTPM]":"20.8","Cell RNA - OE19 [nTPM]":"6.9","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"13.1","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"52.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"15.7","Cell RNA - SH-SY5Y [nTPM]":"18.0","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"5.6","Cell RNA - THP-1 [nTPM]":"8.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"22.7","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"7.9","Cell RNA - U-266\/70 [nTPM]":"71.8","Cell RNA - U-266\/84 [nTPM]":"44.8","Cell RNA - U-698 [nTPM]":"26.9","Cell RNA - U-87 MG [nTPM]":"72.6","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"19.6","Blood RNA - classical monocyte [nTPM]":"3.4","Blood RNA - eosinophil [nTPM]":"25.2","Blood RNA - gdT-cell [nTPM]":"3.7","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"21.2","Blood RNA - naive CD8 T-cell [nTPM]":"13.5","Blood RNA - neutrophil [nTPM]":"12.7","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"12.2","Blood RNA - total PBMC [nTPM]":"9.2","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"5.6","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"5.0","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"9.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"33.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"29.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.2","Single Cell Type RNA - dendritic cells [nTPM]":"9.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.7","Single Cell Type RNA - Early spermatids [nTPM]":"130.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"8.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"13.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"20.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.0","Single Cell Type RNA - Langerhans cells [nTPM]":"15.2","Single Cell Type RNA - Late spermatids [nTPM]":"43.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"11.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.4","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"144.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"9.6","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"17.3","Single Cell Type RNA - Theca cells [nTPM]":"5.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"PDK2","Gene synonym":["PDHK2"],"Ensembl":"ENSG00000005882","Gene description":"Pyruvate dehydrogenase kinase 2","Uniprot":["Q15119"],"Chromosome":"17","Position":"50094737-50112152","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"216.2","tongue":"285.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"123.0","Proximal tubular cells":"131.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008287"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008287":"AB_1079589"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"40.8","Tissue RNA - adrenal gland [nTPM]":"63.8","Tissue RNA - amygdala [nTPM]":"49.9","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"51.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"26.4","Tissue RNA - cerebellum [nTPM]":"65.7","Tissue RNA - cerebral cortex [nTPM]":"58.2","Tissue RNA - cervix [nTPM]":"30.5","Tissue RNA - choroid plexus [nTPM]":"37.1","Tissue RNA - colon [nTPM]":"42.7","Tissue RNA - duodenum [nTPM]":"28.1","Tissue RNA - endometrium 1 [nTPM]":"29.4","Tissue RNA - epididymis [nTPM]":"124.4","Tissue RNA - esophagus [nTPM]":"21.8","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"18.0","Tissue RNA - heart muscle [nTPM]":"116.6","Tissue RNA - hippocampal formation [nTPM]":"50.6","Tissue RNA - hypothalamus [nTPM]":"41.8","Tissue RNA - kidney [nTPM]":"62.7","Tissue RNA - liver [nTPM]":"50.8","Tissue RNA - lung [nTPM]":"15.3","Tissue RNA - lymph node [nTPM]":"10.1","Tissue RNA - medulla oblongata [nTPM]":"40.8","Tissue RNA - midbrain [nTPM]":"44.0","Tissue RNA - ovary [nTPM]":"48.2","Tissue RNA - pancreas [nTPM]":"44.3","Tissue RNA - parathyroid gland [nTPM]":"40.7","Tissue RNA - pituitary gland [nTPM]":"17.0","Tissue RNA - placenta [nTPM]":"14.7","Tissue RNA - pons [nTPM]":"41.8","Tissue RNA - prostate [nTPM]":"23.5","Tissue RNA - rectum [nTPM]":"21.5","Tissue RNA - retina [nTPM]":"14.7","Tissue RNA - salivary gland [nTPM]":"25.7","Tissue RNA - seminal vesicle [nTPM]":"27.4","Tissue RNA - skeletal muscle [nTPM]":"216.2","Tissue RNA - skin 1 [nTPM]":"26.0","Tissue RNA - small intestine [nTPM]":"32.5","Tissue RNA - smooth muscle [nTPM]":"25.7","Tissue RNA - spinal cord [nTPM]":"40.8","Tissue RNA - spleen [nTPM]":"18.4","Tissue RNA - stomach 1 [nTPM]":"33.7","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"44.6","Tissue RNA - thymus [nTPM]":"12.6","Tissue RNA - thyroid gland [nTPM]":"27.3","Tissue RNA - tongue [nTPM]":"285.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"30.9","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"44.6","Cell RNA - A-431 [nTPM]":"12.4","Cell RNA - A549 [nTPM]":"17.5","Cell RNA - AF22 [nTPM]":"20.6","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"16.5","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"13.2","Cell RNA - BJ hTERT+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"21.7","Cell RNA - fHDF\/TERT166 [nTPM]":"37.0","Cell RNA - GAMG [nTPM]":"13.0","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"30.6","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"17.1","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"11.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"33.6","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.5","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"33.7","Cell RNA - HUVEC TERT2 [nTPM]":"17.2","Cell RNA - JURKAT [nTPM]":"20.0","Cell RNA - K-562 [nTPM]":"5.7","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"15.8","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.5","Cell RNA - OE19 [nTPM]":"37.2","Cell RNA - PC-3 [nTPM]":"17.1","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"45.8","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"10.4","Cell RNA - RT4 [nTPM]":"10.4","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"20.7","Cell RNA - SiHa [nTPM]":"18.7","Cell RNA - SK-BR-3 [nTPM]":"5.9","Cell RNA - SK-MEL-30 [nTPM]":"9.0","Cell RNA - SuSa [nTPM]":"25.0","Cell RNA - T-47d [nTPM]":"35.0","Cell RNA - THP-1 [nTPM]":"13.7","Cell RNA - TIME [nTPM]":"8.8","Cell RNA - U-138 MG [nTPM]":"22.5","Cell RNA - U-2 OS [nTPM]":"18.4","Cell RNA - U-2197 [nTPM]":"16.0","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"29.4","Cell RNA - U-266\/84 [nTPM]":"29.9","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"33.3","Cell RNA - U-937 [nTPM]":"4.9","Cell RNA - WM-115 [nTPM]":"15.4","Blood RNA - basophil [nTPM]":"14.3","Blood RNA - classical monocyte [nTPM]":"16.2","Blood RNA - eosinophil [nTPM]":"8.9","Blood RNA - gdT-cell [nTPM]":"16.2","Blood RNA - intermediate monocyte [nTPM]":"12.9","Blood RNA - MAIT T-cell [nTPM]":"12.8","Blood RNA - memory B-cell [nTPM]":"12.9","Blood RNA - memory CD4 T-cell [nTPM]":"14.8","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"18.4","Blood RNA - naive B-cell [nTPM]":"13.8","Blood RNA - naive CD4 T-cell [nTPM]":"17.2","Blood RNA - naive CD8 T-cell [nTPM]":"18.0","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"22.9","Blood RNA - non-classical monocyte [nTPM]":"14.1","Blood RNA - plasmacytoid DC [nTPM]":"25.8","Blood RNA - T-reg [nTPM]":"22.4","Blood RNA - total PBMC [nTPM]":"17.4","Brain RNA - amygdala [nTPM]":"49.9","Brain RNA - basal ganglia [nTPM]":"51.2","Brain RNA - cerebellum [nTPM]":"65.7","Brain RNA - cerebral cortex [nTPM]":"58.2","Brain RNA - hippocampal formation [nTPM]":"50.6","Brain RNA - hypothalamus [nTPM]":"41.8","Brain RNA - medulla oblongata [nTPM]":"40.8","Brain RNA - midbrain [nTPM]":"44.0","Brain RNA - pons [nTPM]":"41.8","Brain RNA - spinal cord [nTPM]":"40.8","Brain RNA - thalamus [nTPM]":"44.6","Brain RNA - white matter [nTPM]":"44.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.3","Single Cell Type RNA - Astrocytes [nTPM]":"18.3","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"11.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"16.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.1","Single Cell Type RNA - Endothelial cells [nTPM]":"11.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.8","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"52.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.9","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.1","Single Cell Type RNA - Late spermatids [nTPM]":"18.9","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"14.5","Single Cell Type RNA - Muller glia cells [nTPM]":"37.3","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"55.2","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"123.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"131.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"11.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.9","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"29.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.3"},{"Gene":"PDK3","Gene synonym":[],"Ensembl":"ENSG00000067992","Gene description":"Pyruvate dehydrogenase kinase 3","Uniprot":["Q15120"],"Chromosome":"X","Position":"24465270-24550466","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.6","Excitatory neurons":"92.8","Inhibitory neurons":"78.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046583","HPA072492"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046583":"AB_2679707","HPA072492":"AB_2686526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"8.2","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"7.4","Tissue RNA - hippocampal formation [nTPM]":"13.2","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"8.8","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"4.8","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"5.8","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"6.0","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"11.6","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"2.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"4.2","Cell RNA - A-431 [nTPM]":"11.5","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"4.2","Cell RNA - AN3-CA [nTPM]":"8.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.9","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"2.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"2.1","Cell RNA - HAP1 [nTPM]":"12.3","Cell RNA - HBEC3-KT [nTPM]":"8.4","Cell RNA - HBF TERT88 [nTPM]":"10.4","Cell RNA - HDLM-2 [nTPM]":"9.7","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"3.3","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"1.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"16.5","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"20.9","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"21.4","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"8.0","Cell RNA - SK-MEL-30 [nTPM]":"5.5","Cell RNA - SuSa [nTPM]":"7.3","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"4.2","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"12.9","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"6.4","Blood RNA - basophil [nTPM]":"13.3","Blood RNA - classical monocyte [nTPM]":"15.4","Blood RNA - eosinophil [nTPM]":"37.9","Blood RNA - gdT-cell [nTPM]":"11.8","Blood RNA - intermediate monocyte [nTPM]":"19.6","Blood RNA - MAIT T-cell [nTPM]":"16.5","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"9.1","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"57.6","Blood RNA - NK-cell [nTPM]":"13.3","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"13.2","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"4.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"15.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"71.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"3.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"92.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"35.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"17.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"10.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"19.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.8","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"PDK4","Gene synonym":[],"Ensembl":"ENSG00000004799","Gene description":"Pyruvate dehydrogenase kinase 4","Uniprot":["Q16654"],"Chromosome":"7","Position":"95583499-95596516","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"2300.1","tongue":"1216.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"681.3","Cardiomyocytes":"764.5","Kupffer cells":"464.0","Proximal enterocytes":"654.2","Smooth muscle cells":"489.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"107.8","thyroid cancer":"89.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"classical monocyte":"32.5","eosinophil":"38.1","intermediate monocyte":"63.5","myeloid DC":"16.8","non-classical monocyte":"39.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"16.8","granulocytes":"38.1","monocytes":"63.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"ASC diff":"482.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056731"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056731":"AB_2683218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"451.2","Tissue RNA - adrenal gland [nTPM]":"216.3","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"48.0","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"388.7","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"43.0","Tissue RNA - cervix [nTPM]":"76.3","Tissue RNA - choroid plexus [nTPM]":"222.0","Tissue RNA - colon [nTPM]":"278.9","Tissue RNA - duodenum [nTPM]":"72.3","Tissue RNA - endometrium 1 [nTPM]":"89.0","Tissue RNA - epididymis [nTPM]":"10.4","Tissue RNA - esophagus [nTPM]":"151.5","Tissue RNA - fallopian tube [nTPM]":"153.5","Tissue RNA - gallbladder [nTPM]":"80.6","Tissue RNA - heart muscle [nTPM]":"480.4","Tissue RNA - hippocampal formation [nTPM]":"40.0","Tissue RNA - hypothalamus [nTPM]":"35.3","Tissue RNA - kidney [nTPM]":"127.8","Tissue RNA - liver [nTPM]":"223.4","Tissue RNA - lung [nTPM]":"120.4","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"44.5","Tissue RNA - midbrain [nTPM]":"41.8","Tissue RNA - ovary [nTPM]":"240.8","Tissue RNA - pancreas [nTPM]":"549.3","Tissue RNA - parathyroid gland [nTPM]":"18.2","Tissue RNA - pituitary gland [nTPM]":"39.9","Tissue RNA - placenta [nTPM]":"104.8","Tissue RNA - pons [nTPM]":"45.3","Tissue RNA - prostate [nTPM]":"91.2","Tissue RNA - rectum [nTPM]":"42.6","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"60.2","Tissue RNA - seminal vesicle [nTPM]":"529.5","Tissue RNA - skeletal muscle [nTPM]":"2300.1","Tissue RNA - skin 1 [nTPM]":"91.9","Tissue RNA - small intestine [nTPM]":"163.3","Tissue RNA - smooth muscle [nTPM]":"62.2","Tissue RNA - spinal cord [nTPM]":"34.8","Tissue RNA - spleen [nTPM]":"99.0","Tissue RNA - stomach 1 [nTPM]":"173.1","Tissue RNA - testis [nTPM]":"13.3","Tissue RNA - thalamus [nTPM]":"39.8","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"72.1","Tissue RNA - tongue [nTPM]":"1216.5","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"187.5","Tissue RNA - vagina [nTPM]":"95.2","Tissue RNA - white matter [nTPM]":"59.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"37.7","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"482.2","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"12.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"66.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"5.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.7","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"2.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"8.6","Cell RNA - SuSa [nTPM]":"2.4","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"1.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"32.5","Blood RNA - eosinophil [nTPM]":"38.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"63.5","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"16.8","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"39.8","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"14.2","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"48.0","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"43.0","Brain RNA - hippocampal formation [nTPM]":"40.0","Brain RNA - hypothalamus [nTPM]":"35.3","Brain RNA - medulla oblongata [nTPM]":"44.5","Brain RNA - midbrain [nTPM]":"41.8","Brain RNA - pons [nTPM]":"45.3","Brain RNA - spinal cord [nTPM]":"34.8","Brain RNA - thalamus [nTPM]":"39.8","Brain RNA - white matter [nTPM]":"59.4","Single Cell Type RNA - Adipocytes [nTPM]":"681.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"154.4","Single Cell Type RNA - B-cells [nTPM]":"6.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"279.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"95.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"764.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"36.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"378.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"67.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"14.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"151.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"108.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"326.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"158.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"347.5","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"199.2","Single Cell Type RNA - Hepatocytes [nTPM]":"130.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"96.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"464.0","Single Cell Type RNA - Langerhans cells [nTPM]":"21.5","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"134.2","Single Cell Type RNA - Macrophages [nTPM]":"204.8","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"19.8","Single Cell Type RNA - Muller glia cells [nTPM]":"8.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"26.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"46.3","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"110.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"654.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"74.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"293.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"489.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"60.5","Single Cell Type RNA - Urothelial cells [nTPM]":"157.4"},{"Gene":"PIK3C2A","Gene synonym":["PI3K-C2alpha"],"Ensembl":"ENSG00000011405","Gene description":"Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha","Uniprot":["O00443"],"Chromosome":"11","Position":"17077730-17207983","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Endocytosis","Exocytosis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cataract","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"217.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037641","HPA037642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA037641":"AB_10671878","HPA037642":"AB_10697081"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.5","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"16.3","Tissue RNA - appendix [nTPM]":"12.3","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"22.5","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"17.4","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"14.9","Tissue RNA - endometrium 1 [nTPM]":"18.0","Tissue RNA - epididymis [nTPM]":"15.7","Tissue RNA - esophagus [nTPM]":"15.4","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"10.5","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"23.5","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"16.6","Tissue RNA - lymph node [nTPM]":"11.3","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"14.1","Tissue RNA - pancreas [nTPM]":"12.3","Tissue RNA - parathyroid gland [nTPM]":"43.6","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"16.4","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"22.4","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"12.3","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"13.0","Tissue RNA - stomach 1 [nTPM]":"18.0","Tissue RNA - testis [nTPM]":"19.3","Tissue RNA - thalamus [nTPM]":"19.6","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"30.7","Tissue RNA - tongue [nTPM]":"12.1","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"53.8","Cell RNA - A549 [nTPM]":"24.1","Cell RNA - AF22 [nTPM]":"39.6","Cell RNA - AN3-CA [nTPM]":"24.8","Cell RNA - ASC diff [nTPM]":"28.0","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"35.3","Cell RNA - BJ [nTPM]":"33.2","Cell RNA - BJ hTERT+ [nTPM]":"35.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.2","Cell RNA - CACO-2 [nTPM]":"58.9","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"16.2","Cell RNA - fHDF\/TERT166 [nTPM]":"28.6","Cell RNA - GAMG [nTPM]":"39.1","Cell RNA - HaCaT [nTPM]":"34.8","Cell RNA - HAP1 [nTPM]":"31.9","Cell RNA - HBEC3-KT [nTPM]":"25.4","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"13.5","Cell RNA - HEK 293 [nTPM]":"27.6","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"28.4","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"30.6","Cell RNA - HL-60 [nTPM]":"12.3","Cell RNA - HMC-1 [nTPM]":"14.9","Cell RNA - HSkMC [nTPM]":"22.2","Cell RNA - hTCEpi [nTPM]":"17.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.6","Cell RNA - hTERT-HME1 [nTPM]":"45.8","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"57.7","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"18.6","Cell RNA - MCF7 [nTPM]":"16.6","Cell RNA - MOLT-4 [nTPM]":"6.6","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"30.1","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"6.9","Cell RNA - RH-30 [nTPM]":"41.1","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"29.6","Cell RNA - RT4 [nTPM]":"47.0","Cell RNA - SCLC-21H [nTPM]":"23.2","Cell RNA - SH-SY5Y [nTPM]":"20.5","Cell RNA - SiHa [nTPM]":"50.6","Cell RNA - SK-BR-3 [nTPM]":"21.4","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"33.0","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"12.3","Cell RNA - TIME [nTPM]":"72.5","Cell RNA - U-138 MG [nTPM]":"19.1","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"50.1","Cell RNA - U-251 MG [nTPM]":"20.4","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"12.8","Cell RNA - U-87 MG [nTPM]":"22.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"16.3","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"22.5","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"10.5","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"19.6","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"93.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.0","Single Cell Type RNA - Astrocytes [nTPM]":"217.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"49.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"29.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.8","Single Cell Type RNA - Early spermatids [nTPM]":"35.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.1","Single Cell Type RNA - Endothelial cells [nTPM]":"87.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.7","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"28.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.4","Single Cell Type RNA - granulocytes [nTPM]":"32.2","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"106.7","Single Cell Type RNA - Hepatocytes [nTPM]":"32.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.2","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"81.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"46.3","Single Cell Type RNA - Langerhans cells [nTPM]":"33.1","Single Cell Type RNA - Late spermatids [nTPM]":"18.6","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"27.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"19.6","Single Cell Type RNA - Muller glia cells [nTPM]":"73.0","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"79.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"13.1","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"29.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.1","Single Cell Type RNA - Spermatocytes [nTPM]":"52.6","Single Cell Type RNA - Spermatogonia [nTPM]":"26.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"143.5","Single Cell Type RNA - T-cells [nTPM]":"25.3","Single Cell Type RNA - Theca cells [nTPM]":"25.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.7","Single Cell Type RNA - Urothelial cells [nTPM]":"37.3"},{"Gene":"PIK3CA","Gene synonym":["PI3K"],"Ensembl":"ENSG00000121879","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha","Uniprot":["P42336"],"Chromosome":"3","Position":"179148114-179240093","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Lipid metabolism","Phagocytosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"126.7","Inhibitory neurons":"122.0","Oligodendrocyte precursor cells":"130.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009985","CAB017804"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"CAB017804":null,"HPA009985":"AB_1079610"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"22.7","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"6.5","Cell RNA - BJ [nTPM]":"10.8","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.0","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"16.1","Cell RNA - EFO-21 [nTPM]":"21.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"5.9","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"32.0","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"22.4","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"4.4","Cell RNA - HHSteC [nTPM]":"10.7","Cell RNA - HL-60 [nTPM]":"13.1","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"16.8","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"15.0","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.8","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"8.5","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"13.9","Cell RNA - RH-30 [nTPM]":"10.0","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"10.8","Cell RNA - SK-MEL-30 [nTPM]":"16.1","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"19.0","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"21.1","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"6.5","Cell RNA - U-2197 [nTPM]":"18.1","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"29.0","Cell RNA - U-87 MG [nTPM]":"11.3","Cell RNA - U-937 [nTPM]":"9.6","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"31.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"60.7","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"15.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.7","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"126.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"31.6","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.1","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"24.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"32.6","Single Cell Type RNA - Macrophages [nTPM]":"20.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"24.5","Single Cell Type RNA - Muller glia cells [nTPM]":"17.4","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"130.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"84.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.8","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"19.9","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"32.0"},{"Gene":"PIK3CB","Gene synonym":["PIK3C1"],"Ensembl":"ENSG00000051382","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta","Uniprot":["P42338"],"Chromosome":"3","Position":"138652698-138834928","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Autophagy","Cell adhesion","Endocytosis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"96.5","Inhibitory neurons":"92.4","Oligodendrocytes":"88.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"115.2","HMC-1":"185.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB031938","HPA042288","HPA064207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Vesicles","Midbody"],"Antibody RRID":{"CAB031938":"AB_2165408","HPA042288":null,"HPA064207":"AB_2685212"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"12.4","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"23.7","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"12.4","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"17.8","Tissue RNA - duodenum [nTPM]":"17.8","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"18.0","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"10.3","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"26.4","Tissue RNA - liver [nTPM]":"11.0","Tissue RNA - lung [nTPM]":"11.2","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"22.3","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"18.1","Tissue RNA - retina [nTPM]":"23.0","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"23.7","Tissue RNA - small intestine [nTPM]":"17.9","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"43.2","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"64.1","Cell RNA - A549 [nTPM]":"21.9","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"13.0","Cell RNA - BEWO [nTPM]":"79.2","Cell RNA - BJ [nTPM]":"14.2","Cell RNA - BJ hTERT+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.7","Cell RNA - CACO-2 [nTPM]":"26.0","Cell RNA - CAPAN-2 [nTPM]":"25.2","Cell RNA - Daudi [nTPM]":"25.0","Cell RNA - EFO-21 [nTPM]":"38.0","Cell RNA - fHDF\/TERT166 [nTPM]":"13.7","Cell RNA - GAMG [nTPM]":"29.1","Cell RNA - HaCaT [nTPM]":"27.5","Cell RNA - HAP1 [nTPM]":"15.1","Cell RNA - HBEC3-KT [nTPM]":"24.1","Cell RNA - HBF TERT88 [nTPM]":"27.3","Cell RNA - HDLM-2 [nTPM]":"31.8","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"115.2","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"17.3","Cell RNA - HHSteC [nTPM]":"11.8","Cell RNA - HL-60 [nTPM]":"30.1","Cell RNA - HMC-1 [nTPM]":"185.1","Cell RNA - HSkMC [nTPM]":"12.4","Cell RNA - hTCEpi [nTPM]":"17.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.2","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"26.4","Cell RNA - HUVEC TERT2 [nTPM]":"21.5","Cell RNA - JURKAT [nTPM]":"12.3","Cell RNA - K-562 [nTPM]":"43.0","Cell RNA - Karpas-707 [nTPM]":"19.0","Cell RNA - LHCN-M2 [nTPM]":"18.1","Cell RNA - MCF7 [nTPM]":"28.6","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"16.6","Cell RNA - OE19 [nTPM]":"49.2","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"11.5","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"24.5","Cell RNA - RT4 [nTPM]":"35.5","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"7.4","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"18.0","Cell RNA - SK-MEL-30 [nTPM]":"56.2","Cell RNA - SuSa [nTPM]":"34.7","Cell RNA - T-47d [nTPM]":"44.8","Cell RNA - THP-1 [nTPM]":"73.0","Cell RNA - TIME [nTPM]":"20.3","Cell RNA - U-138 MG [nTPM]":"8.4","Cell RNA - U-2 OS [nTPM]":"11.7","Cell RNA - U-2197 [nTPM]":"21.2","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"22.1","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"22.8","Cell RNA - U-937 [nTPM]":"27.7","Cell RNA - WM-115 [nTPM]":"14.0","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"5.1","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"5.9","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.3","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"12.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"96.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"19.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"23.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"28.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"29.5","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"25.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.9","Single Cell Type RNA - Spermatocytes [nTPM]":"16.0","Single Cell Type RNA - Spermatogonia [nTPM]":"19.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.9","Single Cell Type RNA - T-cells [nTPM]":"11.6","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.1","Single Cell Type RNA - Urothelial cells [nTPM]":"17.5"},{"Gene":"PIK3CD","Gene synonym":["p110D"],"Ensembl":"ENSG00000171608","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta","Uniprot":["O00329"],"Chromosome":"1","Position":"9651731-9729114","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Chemotaxis","Differentiation","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.9","lymphoid tissue":"50.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"44.0","granulocytes":"25.3","Kupffer cells":"35.2","Microglial cells":"29.0","NK-cells":"29.9","T-cells":"37.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"153.3","NB-4":"65.9","REH":"68.9","THP-1":"65.4","U-937":"78.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015420","HPA044953"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB015420":"AB_831654","HPA044953":"AB_2679153"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"60.9","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"46.9","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"50.4","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"32.0","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"8.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"12.1","Cell RNA - BJ hTERT+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"21.5","Cell RNA - EFO-21 [nTPM]":"4.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"16.2","Cell RNA - HDLM-2 [nTPM]":"153.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"5.1","Cell RNA - HL-60 [nTPM]":"56.0","Cell RNA - HMC-1 [nTPM]":"18.7","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.2","Cell RNA - hTERT-HME1 [nTPM]":"9.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"14.9","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"15.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"65.9","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"68.9","Cell RNA - RH-30 [nTPM]":"13.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"65.4","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"4.9","Cell RNA - U-266\/84 [nTPM]":"4.9","Cell RNA - U-698 [nTPM]":"30.1","Cell RNA - U-87 MG [nTPM]":"16.7","Cell RNA - U-937 [nTPM]":"78.6","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"18.0","Blood RNA - classical monocyte [nTPM]":"23.5","Blood RNA - eosinophil [nTPM]":"40.2","Blood RNA - gdT-cell [nTPM]":"21.6","Blood RNA - intermediate monocyte [nTPM]":"23.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.9","Blood RNA - myeloid DC [nTPM]":"22.5","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"20.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.1","Blood RNA - neutrophil [nTPM]":"63.2","Blood RNA - NK-cell [nTPM]":"25.9","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"25.7","Blood RNA - T-reg [nTPM]":"13.3","Blood RNA - total PBMC [nTPM]":"38.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"44.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"23.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"37.1","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"PIK3CG","Gene synonym":[],"Ensembl":"ENSG00000105851","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma","Uniprot":["P48736"],"Chromosome":"7","Position":"106865278-106908980","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Chemotaxis","Endocytosis","Immunity","Inflammatory response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"43.6","lymphoid tissue":"19.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"24.9","dendritic cells":"26.5","Early spermatids":"28.9","granulocytes":"20.8","monocytes":"23.8","NK-cells":"25.7","Plasma cells":"88.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"29.4","HL-60":"28.8","HMC-1":"34.9","Karpas-707":"29.1","MOLT-4":"56.0","U-266\/70":"71.4","U-937":"52.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069976"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA069976":"AB_2686224"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"43.6","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"4.2","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"11.0","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"16.4","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"19.7","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"29.4","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"17.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"28.8","Cell RNA - HMC-1 [nTPM]":"34.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"11.0","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"20.6","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"56.0","Cell RNA - NB-4 [nTPM]":"17.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"14.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"19.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"71.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"27.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"52.1","Cell RNA - WM-115 [nTPM]":"6.7","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"24.3","Blood RNA - gdT-cell [nTPM]":"8.8","Blood RNA - intermediate monocyte [nTPM]":"17.8","Blood RNA - MAIT T-cell [nTPM]":"8.1","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"9.4","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"5.9","Blood RNA - neutrophil [nTPM]":"22.7","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"43.7","Blood RNA - plasmacytoid DC [nTPM]":"8.6","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"6.8","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"24.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"26.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"28.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"8.3","Single Cell Type RNA - Late spermatids [nTPM]":"18.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"18.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"23.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"88.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.6","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"18.1","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"PRKDC","Gene synonym":["DNA-PKC","DNA-PKcs","DNAPK","DNAPKc","DNPK1","HYRC","HYRC1","p350","p460","XRCC7"],"Ensembl":"ENSG00000253729","Gene description":"Protein kinase, DNA-activated, catalytic subunit","Uniprot":["P78527"],"Chromosome":"8","Position":"47773111-47960178","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","DNA damage","DNA recombination","DNA repair","Immunity","Innate immunity","Ribosome biogenesis"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005167","HPA035174"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005167":"AB_2172845","HPA035174":"AB_2674504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"14.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"19.2","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"20.1","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"14.8","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"23.8","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"26.4","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"13.4","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"18.7","Tissue RNA - vagina [nTPM]":"17.5","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"123.5","Cell RNA - A549 [nTPM]":"103.4","Cell RNA - AF22 [nTPM]":"98.4","Cell RNA - AN3-CA [nTPM]":"93.9","Cell RNA - ASC diff [nTPM]":"59.9","Cell RNA - ASC TERT1 [nTPM]":"63.0","Cell RNA - BEWO [nTPM]":"41.6","Cell RNA - BJ [nTPM]":"51.2","Cell RNA - BJ hTERT+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.9","Cell RNA - CACO-2 [nTPM]":"68.0","Cell RNA - CAPAN-2 [nTPM]":"39.6","Cell RNA - Daudi [nTPM]":"117.1","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"63.3","Cell RNA - GAMG [nTPM]":"52.3","Cell RNA - HaCaT [nTPM]":"68.5","Cell RNA - HAP1 [nTPM]":"131.3","Cell RNA - HBEC3-KT [nTPM]":"70.2","Cell RNA - HBF TERT88 [nTPM]":"109.3","Cell RNA - HDLM-2 [nTPM]":"26.3","Cell RNA - HEK 293 [nTPM]":"81.8","Cell RNA - HEL [nTPM]":"230.2","Cell RNA - HeLa [nTPM]":"92.1","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"25.8","Cell RNA - HL-60 [nTPM]":"88.6","Cell RNA - HMC-1 [nTPM]":"46.0","Cell RNA - HSkMC [nTPM]":"45.9","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.3","Cell RNA - hTERT-HME1 [nTPM]":"115.3","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"73.4","Cell RNA - JURKAT [nTPM]":"79.5","Cell RNA - K-562 [nTPM]":"156.6","Cell RNA - Karpas-707 [nTPM]":"48.0","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"57.7","Cell RNA - MOLT-4 [nTPM]":"125.8","Cell RNA - NB-4 [nTPM]":"72.3","Cell RNA - NTERA-2 [nTPM]":"108.6","Cell RNA - OE19 [nTPM]":"85.6","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"60.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"41.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.5","Cell RNA - RT4 [nTPM]":"104.4","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"62.5","Cell RNA - SiHa [nTPM]":"158.1","Cell RNA - SK-BR-3 [nTPM]":"50.6","Cell RNA - SK-MEL-30 [nTPM]":"51.1","Cell RNA - SuSa [nTPM]":"60.2","Cell RNA - T-47d [nTPM]":"72.6","Cell RNA - THP-1 [nTPM]":"60.1","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"91.5","Cell RNA - U-2 OS [nTPM]":"78.0","Cell RNA - U-2197 [nTPM]":"73.0","Cell RNA - U-251 MG [nTPM]":"104.2","Cell RNA - U-266\/70 [nTPM]":"41.3","Cell RNA - U-266\/84 [nTPM]":"56.7","Cell RNA - U-698 [nTPM]":"162.8","Cell RNA - U-87 MG [nTPM]":"51.7","Cell RNA - U-937 [nTPM]":"97.9","Cell RNA - WM-115 [nTPM]":"75.6","Blood RNA - basophil [nTPM]":"11.4","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"8.7","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"13.1","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.2","Blood RNA - naive CD8 T-cell [nTPM]":"10.3","Blood RNA - neutrophil [nTPM]":"7.7","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"15.3","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"73.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.1","Single Cell Type RNA - Astrocytes [nTPM]":"56.8","Single Cell Type RNA - B-cells [nTPM]":"67.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"77.4","Single Cell Type RNA - Bipolar cells [nTPM]":"103.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"44.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.1","Single Cell Type RNA - dendritic cells [nTPM]":"81.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.9","Single Cell Type RNA - Early spermatids [nTPM]":"29.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"166.5","Single Cell Type RNA - Endothelial cells [nTPM]":"59.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"147.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.6","Single Cell Type RNA - Fibroblasts [nTPM]":"73.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.6","Single Cell Type RNA - granulocytes [nTPM]":"45.6","Single Cell Type RNA - Granulosa cells [nTPM]":"105.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.9","Single Cell Type RNA - Horizontal cells [nTPM]":"104.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"77.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"54.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"63.6","Single Cell Type RNA - Muller glia cells [nTPM]":"73.1","Single Cell Type RNA - NK-cells [nTPM]":"57.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"82.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.6","Single Cell Type RNA - Peritubular cells [nTPM]":"69.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.6","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.3","Single Cell Type RNA - Spermatocytes [nTPM]":"100.7","Single Cell Type RNA - Spermatogonia [nTPM]":"106.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - T-cells [nTPM]":"71.0","Single Cell Type RNA - Theca cells [nTPM]":"143.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.4"},{"Gene":"RIOK1","Gene synonym":["AD034","bA288G3.1","FLJ30006","RRP10"],"Ensembl":"ENSG00000124784","Gene description":"RIO kinase 1","Uniprot":["Q9BRS2"],"Chromosome":"6","Position":"7389793-7418037","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["Hydrolase","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017866","HPA051446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017866":"AB_2669670","HPA051446":"AB_2681488"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.1","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"11.0","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"7.1","Tissue RNA - lymph node [nTPM]":"14.0","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"5.1","Tissue RNA - ovary [nTPM]":"10.9","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"8.6","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"8.1","Tissue RNA - skeletal muscle [nTPM]":"11.5","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"10.8","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"19.9","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"20.4","Cell RNA - A549 [nTPM]":"11.7","Cell RNA - AF22 [nTPM]":"18.3","Cell RNA - AN3-CA [nTPM]":"45.8","Cell RNA - ASC diff [nTPM]":"27.0","Cell RNA - ASC TERT1 [nTPM]":"22.6","Cell RNA - BEWO [nTPM]":"28.7","Cell RNA - BJ [nTPM]":"25.6","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"51.8","Cell RNA - EFO-21 [nTPM]":"43.3","Cell RNA - fHDF\/TERT166 [nTPM]":"19.7","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"20.3","Cell RNA - HAP1 [nTPM]":"45.7","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"29.0","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"49.6","Cell RNA - HEL [nTPM]":"28.3","Cell RNA - HeLa [nTPM]":"18.3","Cell RNA - Hep G2 [nTPM]":"39.4","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"81.5","Cell RNA - HMC-1 [nTPM]":"37.5","Cell RNA - HSkMC [nTPM]":"17.2","Cell RNA - hTCEpi [nTPM]":"27.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.1","Cell RNA - hTERT-HME1 [nTPM]":"50.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.5","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"38.6","Cell RNA - K-562 [nTPM]":"72.1","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"26.7","Cell RNA - MOLT-4 [nTPM]":"56.8","Cell RNA - NB-4 [nTPM]":"50.2","Cell RNA - NTERA-2 [nTPM]":"39.6","Cell RNA - OE19 [nTPM]":"36.3","Cell RNA - PC-3 [nTPM]":"26.1","Cell RNA - REH [nTPM]":"42.9","Cell RNA - RH-30 [nTPM]":"23.3","Cell RNA - RPMI-8226 [nTPM]":"56.6","Cell RNA - RPTEC TERT1 [nTPM]":"13.8","Cell RNA - RT4 [nTPM]":"19.9","Cell RNA - SCLC-21H [nTPM]":"60.8","Cell RNA - SH-SY5Y [nTPM]":"30.4","Cell RNA - SiHa [nTPM]":"20.8","Cell RNA - SK-BR-3 [nTPM]":"13.3","Cell RNA - SK-MEL-30 [nTPM]":"41.6","Cell RNA - SuSa [nTPM]":"48.4","Cell RNA - T-47d [nTPM]":"18.9","Cell RNA - THP-1 [nTPM]":"28.4","Cell RNA - TIME [nTPM]":"19.9","Cell RNA - U-138 MG [nTPM]":"24.4","Cell RNA - U-2 OS [nTPM]":"18.9","Cell RNA - U-2197 [nTPM]":"17.5","Cell RNA - U-251 MG [nTPM]":"38.3","Cell RNA - U-266\/70 [nTPM]":"17.1","Cell RNA - U-266\/84 [nTPM]":"33.0","Cell RNA - U-698 [nTPM]":"75.7","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"44.0","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"12.0","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"9.0","Blood RNA - gdT-cell [nTPM]":"14.9","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"18.0","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"15.4","Blood RNA - memory CD8 T-cell [nTPM]":"15.9","Blood RNA - myeloid DC [nTPM]":"20.5","Blood RNA - naive B-cell [nTPM]":"23.0","Blood RNA - naive CD4 T-cell [nTPM]":"17.8","Blood RNA - naive CD8 T-cell [nTPM]":"19.2","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"26.7","Blood RNA - non-classical monocyte [nTPM]":"14.0","Blood RNA - plasmacytoid DC [nTPM]":"17.3","Blood RNA - T-reg [nTPM]":"16.2","Blood RNA - total PBMC [nTPM]":"11.3","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"5.1","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"27.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"35.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.1","Single Cell Type RNA - dendritic cells [nTPM]":"25.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.9","Single Cell Type RNA - Early spermatids [nTPM]":"74.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.7","Single Cell Type RNA - Fibroblasts [nTPM]":"29.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.1","Single Cell Type RNA - granulocytes [nTPM]":"33.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.4","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"11.2","Single Cell Type RNA - Langerhans cells [nTPM]":"25.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.5","Single Cell Type RNA - Leydig cells [nTPM]":"19.9","Single Cell Type RNA - Macrophages [nTPM]":"19.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"15.1","Single Cell Type RNA - Muller glia cells [nTPM]":"8.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.2","Single Cell Type RNA - Peritubular cells [nTPM]":"19.9","Single Cell Type RNA - Plasma cells [nTPM]":"27.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.9","Single Cell Type RNA - Spermatocytes [nTPM]":"58.9","Single Cell Type RNA - Spermatogonia [nTPM]":"75.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"29.0","Single Cell Type RNA - Theca cells [nTPM]":"23.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.9","Single Cell Type RNA - Urothelial cells [nTPM]":"23.8"},{"Gene":"RIOK2","Gene synonym":["FLJ11159"],"Ensembl":"ENSG00000058729","Gene description":"RIO kinase 2","Uniprot":["Q9BVS4"],"Chromosome":"5","Position":"97160867-97183247","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Ribosome biogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005681"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA005681":"AB_1856286"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"14.6","Tissue RNA - amygdala [nTPM]":"12.5","Tissue RNA - appendix [nTPM]":"13.5","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"21.5","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"14.1","Tissue RNA - colon [nTPM]":"13.3","Tissue RNA - duodenum [nTPM]":"13.0","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"16.3","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"18.1","Tissue RNA - lung [nTPM]":"10.3","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"13.5","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"16.7","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"15.1","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"13.5","Tissue RNA - prostate [nTPM]":"12.0","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"19.4","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"21.4","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"13.9","Tissue RNA - spleen [nTPM]":"14.6","Tissue RNA - stomach 1 [nTPM]":"13.3","Tissue RNA - testis [nTPM]":"12.6","Tissue RNA - thalamus [nTPM]":"13.7","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"12.1","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"19.0","Cell RNA - A549 [nTPM]":"22.0","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"38.5","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"32.1","Cell RNA - BJ [nTPM]":"48.1","Cell RNA - BJ hTERT+ [nTPM]":"29.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.2","Cell RNA - CACO-2 [nTPM]":"30.4","Cell RNA - CAPAN-2 [nTPM]":"32.5","Cell RNA - Daudi [nTPM]":"41.7","Cell RNA - EFO-21 [nTPM]":"53.1","Cell RNA - fHDF\/TERT166 [nTPM]":"21.3","Cell RNA - GAMG [nTPM]":"51.6","Cell RNA - HaCaT [nTPM]":"21.7","Cell RNA - HAP1 [nTPM]":"34.2","Cell RNA - HBEC3-KT [nTPM]":"27.4","Cell RNA - HBF TERT88 [nTPM]":"44.9","Cell RNA - HDLM-2 [nTPM]":"29.3","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"44.0","Cell RNA - Hep G2 [nTPM]":"42.9","Cell RNA - HHSteC [nTPM]":"23.6","Cell RNA - HL-60 [nTPM]":"38.5","Cell RNA - HMC-1 [nTPM]":"27.2","Cell RNA - HSkMC [nTPM]":"18.5","Cell RNA - hTCEpi [nTPM]":"20.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.1","Cell RNA - hTERT-HME1 [nTPM]":"39.8","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"27.0","Cell RNA - JURKAT [nTPM]":"30.8","Cell RNA - K-562 [nTPM]":"31.7","Cell RNA - Karpas-707 [nTPM]":"25.4","Cell RNA - LHCN-M2 [nTPM]":"38.0","Cell RNA - MCF7 [nTPM]":"31.9","Cell RNA - MOLT-4 [nTPM]":"46.4","Cell RNA - NB-4 [nTPM]":"47.8","Cell RNA - NTERA-2 [nTPM]":"22.5","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"23.9","Cell RNA - REH [nTPM]":"51.9","Cell RNA - RH-30 [nTPM]":"38.3","Cell RNA - RPMI-8226 [nTPM]":"61.9","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"17.9","Cell RNA - SiHa [nTPM]":"27.5","Cell RNA - SK-BR-3 [nTPM]":"28.3","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"29.6","Cell RNA - T-47d [nTPM]":"29.6","Cell RNA - THP-1 [nTPM]":"36.4","Cell RNA - TIME [nTPM]":"28.5","Cell RNA - U-138 MG [nTPM]":"41.2","Cell RNA - U-2 OS [nTPM]":"28.9","Cell RNA - U-2197 [nTPM]":"33.0","Cell RNA - U-251 MG [nTPM]":"51.8","Cell RNA - U-266\/70 [nTPM]":"25.3","Cell RNA - U-266\/84 [nTPM]":"36.4","Cell RNA - U-698 [nTPM]":"95.2","Cell RNA - U-87 MG [nTPM]":"24.0","Cell RNA - U-937 [nTPM]":"39.7","Cell RNA - WM-115 [nTPM]":"38.4","Blood RNA - basophil [nTPM]":"17.9","Blood RNA - classical monocyte [nTPM]":"26.2","Blood RNA - eosinophil [nTPM]":"15.8","Blood RNA - gdT-cell [nTPM]":"24.6","Blood RNA - intermediate monocyte [nTPM]":"30.7","Blood RNA - MAIT T-cell [nTPM]":"34.4","Blood RNA - memory B-cell [nTPM]":"24.0","Blood RNA - memory CD4 T-cell [nTPM]":"31.5","Blood RNA - memory CD8 T-cell [nTPM]":"27.8","Blood RNA - myeloid DC [nTPM]":"29.4","Blood RNA - naive B-cell [nTPM]":"18.6","Blood RNA - naive CD4 T-cell [nTPM]":"33.9","Blood RNA - naive CD8 T-cell [nTPM]":"36.5","Blood RNA - neutrophil [nTPM]":"5.0","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"23.8","Blood RNA - plasmacytoid DC [nTPM]":"29.2","Blood RNA - T-reg [nTPM]":"31.7","Blood RNA - total PBMC [nTPM]":"22.7","Brain RNA - amygdala [nTPM]":"12.5","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"13.5","Brain RNA - pons [nTPM]":"13.5","Brain RNA - spinal cord [nTPM]":"13.9","Brain RNA - thalamus [nTPM]":"13.7","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"16.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"16.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"17.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"17.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"14.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.8","Single Cell Type RNA - Fibroblasts [nTPM]":"21.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.5","Single Cell Type RNA - granulocytes [nTPM]":"27.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.4","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.1","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"19.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.9","Single Cell Type RNA - Spermatocytes [nTPM]":"23.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"19.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"12.0"},{"Gene":"RIOK3","Gene synonym":["SUDD"],"Ensembl":"ENSG00000101782","Gene description":"RIO kinase 3","Uniprot":["O14730"],"Chromosome":"18","Position":"23453287-23486603","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","Ribosome biogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"174.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"338.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001620","HPA024184"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Golgi apparatus","Centriolar satellite"],"Antibody RRID":{"HPA001620":"AB_1079815","HPA024184":"AB_1856289"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.1","Tissue RNA - adrenal gland [nTPM]":"18.5","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"20.4","Tissue RNA - basal ganglia [nTPM]":"7.1","Tissue RNA - bone marrow [nTPM]":"174.3","Tissue RNA - breast [nTPM]":"19.2","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"8.3","Tissue RNA - colon [nTPM]":"47.5","Tissue RNA - duodenum [nTPM]":"51.6","Tissue RNA - endometrium 1 [nTPM]":"16.7","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"65.5","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"24.3","Tissue RNA - heart muscle [nTPM]":"32.7","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"29.6","Tissue RNA - liver [nTPM]":"55.6","Tissue RNA - lung [nTPM]":"22.7","Tissue RNA - lymph node [nTPM]":"22.8","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"27.6","Tissue RNA - parathyroid gland [nTPM]":"22.8","Tissue RNA - pituitary gland [nTPM]":"5.4","Tissue RNA - placenta [nTPM]":"34.9","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"20.1","Tissue RNA - rectum [nTPM]":"43.5","Tissue RNA - retina [nTPM]":"19.6","Tissue RNA - salivary gland [nTPM]":"23.2","Tissue RNA - seminal vesicle [nTPM]":"14.5","Tissue RNA - skeletal muscle [nTPM]":"52.9","Tissue RNA - skin 1 [nTPM]":"33.3","Tissue RNA - small intestine [nTPM]":"62.5","Tissue RNA - smooth muscle [nTPM]":"19.7","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"21.5","Tissue RNA - stomach 1 [nTPM]":"38.5","Tissue RNA - testis [nTPM]":"36.6","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"21.5","Tissue RNA - thyroid gland [nTPM]":"22.2","Tissue RNA - tongue [nTPM]":"48.8","Tissue RNA - tonsil [nTPM]":"30.2","Tissue RNA - urinary bladder [nTPM]":"25.8","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"41.9","Cell RNA - A549 [nTPM]":"15.7","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"25.0","Cell RNA - ASC diff [nTPM]":"31.8","Cell RNA - ASC TERT1 [nTPM]":"37.7","Cell RNA - BEWO [nTPM]":"28.5","Cell RNA - BJ [nTPM]":"38.9","Cell RNA - BJ hTERT+ [nTPM]":"29.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.4","Cell RNA - CACO-2 [nTPM]":"17.3","Cell RNA - CAPAN-2 [nTPM]":"47.5","Cell RNA - Daudi [nTPM]":"27.6","Cell RNA - EFO-21 [nTPM]":"52.3","Cell RNA - fHDF\/TERT166 [nTPM]":"43.7","Cell RNA - GAMG [nTPM]":"26.9","Cell RNA - HaCaT [nTPM]":"57.6","Cell RNA - HAP1 [nTPM]":"25.9","Cell RNA - HBEC3-KT [nTPM]":"45.4","Cell RNA - HBF TERT88 [nTPM]":"38.9","Cell RNA - HDLM-2 [nTPM]":"29.5","Cell RNA - HEK 293 [nTPM]":"12.0","Cell RNA - HEL [nTPM]":"25.9","Cell RNA - HeLa [nTPM]":"26.9","Cell RNA - Hep G2 [nTPM]":"22.2","Cell RNA - HHSteC [nTPM]":"71.7","Cell RNA - HL-60 [nTPM]":"74.7","Cell RNA - HMC-1 [nTPM]":"25.8","Cell RNA - HSkMC [nTPM]":"39.0","Cell RNA - hTCEpi [nTPM]":"91.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.1","Cell RNA - hTERT-HME1 [nTPM]":"66.7","Cell RNA - hTERT-RPE1 [nTPM]":"36.7","Cell RNA - HUVEC TERT2 [nTPM]":"38.4","Cell RNA - JURKAT [nTPM]":"19.2","Cell RNA - K-562 [nTPM]":"39.8","Cell RNA - Karpas-707 [nTPM]":"34.7","Cell RNA - LHCN-M2 [nTPM]":"45.0","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"25.8","Cell RNA - NB-4 [nTPM]":"15.6","Cell RNA - NTERA-2 [nTPM]":"17.6","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"31.3","Cell RNA - REH [nTPM]":"31.3","Cell RNA - RH-30 [nTPM]":"33.2","Cell RNA - RPMI-8226 [nTPM]":"41.2","Cell RNA - RPTEC TERT1 [nTPM]":"39.3","Cell RNA - RT4 [nTPM]":"50.0","Cell RNA - SCLC-21H [nTPM]":"39.5","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"50.1","Cell RNA - SK-BR-3 [nTPM]":"28.4","Cell RNA - SK-MEL-30 [nTPM]":"37.4","Cell RNA - SuSa [nTPM]":"41.0","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.0","Cell RNA - TIME [nTPM]":"63.7","Cell RNA - U-138 MG [nTPM]":"48.4","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"21.2","Cell RNA - U-251 MG [nTPM]":"28.9","Cell RNA - U-266\/70 [nTPM]":"66.1","Cell RNA - U-266\/84 [nTPM]":"56.0","Cell RNA - U-698 [nTPM]":"38.2","Cell RNA - U-87 MG [nTPM]":"31.0","Cell RNA - U-937 [nTPM]":"36.7","Cell RNA - WM-115 [nTPM]":"38.2","Blood RNA - basophil [nTPM]":"50.1","Blood RNA - classical monocyte [nTPM]":"24.5","Blood RNA - eosinophil [nTPM]":"14.8","Blood RNA - gdT-cell [nTPM]":"15.0","Blood RNA - intermediate monocyte [nTPM]":"34.6","Blood RNA - MAIT T-cell [nTPM]":"10.8","Blood RNA - memory B-cell [nTPM]":"14.0","Blood RNA - memory CD4 T-cell [nTPM]":"12.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.6","Blood RNA - myeloid DC [nTPM]":"19.1","Blood RNA - naive B-cell [nTPM]":"18.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.2","Blood RNA - neutrophil [nTPM]":"17.2","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"39.0","Blood RNA - plasmacytoid DC [nTPM]":"8.6","Blood RNA - T-reg [nTPM]":"19.4","Blood RNA - total PBMC [nTPM]":"20.7","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.1","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"49.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.7","Single Cell Type RNA - Astrocytes [nTPM]":"23.2","Single Cell Type RNA - B-cells [nTPM]":"46.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"92.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"78.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"113.8","Single Cell Type RNA - Bipolar cells [nTPM]":"44.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"69.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"81.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.0","Single Cell Type RNA - dendritic cells [nTPM]":"74.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"338.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"51.0","Single Cell Type RNA - Early spermatids [nTPM]":"271.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"130.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"85.5","Single Cell Type RNA - Endothelial cells [nTPM]":"44.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.8","Single Cell Type RNA - Erythroid cells [nTPM]":"259.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"64.6","Single Cell Type RNA - Fibroblasts [nTPM]":"48.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"93.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"267.2","Single Cell Type RNA - granulocytes [nTPM]":"63.3","Single Cell Type RNA - Granulosa cells [nTPM]":"40.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"88.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"41.1","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"119.9","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"59.9","Single Cell Type RNA - Langerhans cells [nTPM]":"51.2","Single Cell Type RNA - Late spermatids [nTPM]":"305.8","Single Cell Type RNA - Leydig cells [nTPM]":"22.4","Single Cell Type RNA - Macrophages [nTPM]":"85.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"80.6","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"148.4","Single Cell Type RNA - Paneth cells [nTPM]":"210.7","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"63.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"118.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"199.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"72.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"46.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.6","Single Cell Type RNA - Spermatocytes [nTPM]":"28.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"164.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.4","Single Cell Type RNA - T-cells [nTPM]":"57.3","Single Cell Type RNA - Theca cells [nTPM]":"71.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.2","Single Cell Type RNA - Urothelial cells [nTPM]":"244.4"},{"Gene":"SMG1","Gene synonym":["ATX","KIAA0421","LIP"],"Ensembl":"ENSG00000157106","Gene description":"SMG1 nonsense mediated mRNA decay associated PI3K related kinase","Uniprot":["Q96Q15"],"Chromosome":"16","Position":"18804860-18926408","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Nonsense-mediated mRNA decay"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"31.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"31.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006870","HPA031623","HPA073972"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006870":"AB_1079725","HPA031623":"AB_2673962","HPA073972":"AB_2686648"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.9","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"39.0","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"42.6","Tissue RNA - cerebral cortex [nTPM]":"12.6","Tissue RNA - cervix [nTPM]":"13.4","Tissue RNA - choroid plexus [nTPM]":"11.9","Tissue RNA - colon [nTPM]":"14.4","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"12.1","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"14.6","Tissue RNA - liver [nTPM]":"17.8","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"21.6","Tissue RNA - medulla oblongata [nTPM]":"7.5","Tissue RNA - midbrain [nTPM]":"6.7","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"12.1","Tissue RNA - rectum [nTPM]":"15.9","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"12.0","Tissue RNA - seminal vesicle [nTPM]":"10.9","Tissue RNA - skeletal muscle [nTPM]":"53.1","Tissue RNA - skin 1 [nTPM]":"42.0","Tissue RNA - small intestine [nTPM]":"13.6","Tissue RNA - smooth muscle [nTPM]":"13.2","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"15.9","Tissue RNA - stomach 1 [nTPM]":"12.8","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"29.9","Tissue RNA - thyroid gland [nTPM]":"18.1","Tissue RNA - tongue [nTPM]":"35.4","Tissue RNA - tonsil [nTPM]":"19.1","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"13.2","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"42.2","Cell RNA - A549 [nTPM]":"27.5","Cell RNA - AF22 [nTPM]":"25.5","Cell RNA - AN3-CA [nTPM]":"18.1","Cell RNA - ASC diff [nTPM]":"28.6","Cell RNA - ASC TERT1 [nTPM]":"29.9","Cell RNA - BEWO [nTPM]":"18.8","Cell RNA - BJ [nTPM]":"19.1","Cell RNA - BJ hTERT+ [nTPM]":"18.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.7","Cell RNA - CACO-2 [nTPM]":"24.4","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"57.5","Cell RNA - EFO-21 [nTPM]":"26.8","Cell RNA - fHDF\/TERT166 [nTPM]":"26.8","Cell RNA - GAMG [nTPM]":"21.5","Cell RNA - HaCaT [nTPM]":"23.3","Cell RNA - HAP1 [nTPM]":"29.6","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"32.3","Cell RNA - HDLM-2 [nTPM]":"37.2","Cell RNA - HEK 293 [nTPM]":"18.4","Cell RNA - HEL [nTPM]":"26.2","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"31.4","Cell RNA - HHSteC [nTPM]":"23.1","Cell RNA - HL-60 [nTPM]":"35.7","Cell RNA - HMC-1 [nTPM]":"19.9","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"27.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.4","Cell RNA - hTERT-HME1 [nTPM]":"50.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.1","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"30.7","Cell RNA - K-562 [nTPM]":"41.0","Cell RNA - Karpas-707 [nTPM]":"31.0","Cell RNA - LHCN-M2 [nTPM]":"22.8","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"24.8","Cell RNA - NB-4 [nTPM]":"20.9","Cell RNA - NTERA-2 [nTPM]":"27.2","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"15.7","Cell RNA - REH [nTPM]":"28.4","Cell RNA - RH-30 [nTPM]":"34.2","Cell RNA - RPMI-8226 [nTPM]":"19.8","Cell RNA - RPTEC TERT1 [nTPM]":"17.6","Cell RNA - RT4 [nTPM]":"32.1","Cell RNA - SCLC-21H [nTPM]":"23.0","Cell RNA - SH-SY5Y [nTPM]":"17.6","Cell RNA - SiHa [nTPM]":"29.9","Cell RNA - SK-BR-3 [nTPM]":"19.9","Cell RNA - SK-MEL-30 [nTPM]":"20.8","Cell RNA - SuSa [nTPM]":"20.8","Cell RNA - T-47d [nTPM]":"15.9","Cell RNA - THP-1 [nTPM]":"22.3","Cell RNA - TIME [nTPM]":"37.0","Cell RNA - U-138 MG [nTPM]":"30.2","Cell RNA - U-2 OS [nTPM]":"20.4","Cell RNA - U-2197 [nTPM]":"19.0","Cell RNA - U-251 MG [nTPM]":"28.7","Cell RNA - U-266\/70 [nTPM]":"15.8","Cell RNA - U-266\/84 [nTPM]":"21.8","Cell RNA - U-698 [nTPM]":"37.0","Cell RNA - U-87 MG [nTPM]":"20.2","Cell RNA - U-937 [nTPM]":"27.1","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"31.7","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"3.2","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.8","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"7.6","Blood RNA - naive CD4 T-cell [nTPM]":"5.7","Blood RNA - naive CD8 T-cell [nTPM]":"5.1","Blood RNA - neutrophil [nTPM]":"8.4","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"7.2","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"42.6","Brain RNA - cerebral cortex [nTPM]":"12.6","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"7.5","Brain RNA - midbrain [nTPM]":"6.7","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"83.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.4","Single Cell Type RNA - Astrocytes [nTPM]":"58.4","Single Cell Type RNA - B-cells [nTPM]":"98.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"193.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"112.1","Single Cell Type RNA - Bipolar cells [nTPM]":"52.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"71.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"40.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"67.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"75.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.3","Single Cell Type RNA - dendritic cells [nTPM]":"97.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"65.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.7","Single Cell Type RNA - Early spermatids [nTPM]":"20.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"88.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"81.1","Single Cell Type RNA - Endothelial cells [nTPM]":"66.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.4","Single Cell Type RNA - Erythroid cells [nTPM]":"44.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"81.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.0","Single Cell Type RNA - Fibroblasts [nTPM]":"57.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"90.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"140.0","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"66.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.9","Single Cell Type RNA - Hepatocytes [nTPM]":"46.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.1","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"75.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.8","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"48.0","Single Cell Type RNA - Langerhans cells [nTPM]":"112.8","Single Cell Type RNA - Late spermatids [nTPM]":"24.9","Single Cell Type RNA - Leydig cells [nTPM]":"29.8","Single Cell Type RNA - Macrophages [nTPM]":"82.5","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"61.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.5","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"87.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.6","Single Cell Type RNA - Paneth cells [nTPM]":"76.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"82.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"94.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"45.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"118.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"63.1","Single Cell Type RNA - Spermatocytes [nTPM]":"49.6","Single Cell Type RNA - Spermatogonia [nTPM]":"32.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"204.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.0","Single Cell Type RNA - T-cells [nTPM]":"97.6","Single Cell Type RNA - Theca cells [nTPM]":"37.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.4","Single Cell Type RNA - Urothelial cells [nTPM]":"95.4"},{"Gene":"TRPM6","Gene synonym":["CHAK2","FLJ22628","HOMG","HSH"],"Ensembl":"ENSG00000119121","Gene description":"Transient receptor potential cation channel subfamily M member 6","Uniprot":["Q9BX84"],"Chromosome":"9","Position":"74722495-74888094","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"6.6","intestine":"16.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"128.9","Glandular and luminal cells":"36.5","Microglial cells":"39.4","Oligodendrocytes":"81.1","Proximal enterocytes":"23.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"23.1","neutrophil":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"granulocytes":"23.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.8","HeLa":"2.4","Karpas-707":"1.3","RT4":"3.8","U-266\/70":"1.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"2.6","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"16.6","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"7.9","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"23.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"7.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"128.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"81.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"13.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"TRPM7","Gene synonym":["CHAK1","LTRPC7","TRP-PLIK"],"Ensembl":"ENSG00000092439","Gene description":"Transient receptor potential cation channel subfamily M member 7","Uniprot":["Q96QT4"],"Chromosome":"15","Position":"50552473-50686797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Necrosis","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"108.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"122.2","Oligodendrocytes":"109.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"122.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035522","HPA052173"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA035522":null,"HPA052173":"AB_2681749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"21.4","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"29.3","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"14.4","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"14.6","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"9.4","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"22.9","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"16.4","Tissue RNA - pancreas [nTPM]":"12.2","Tissue RNA - parathyroid gland [nTPM]":"108.9","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"13.3","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"10.5","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"10.6","Tissue RNA - skeletal muscle [nTPM]":"7.8","Tissue RNA - skin 1 [nTPM]":"16.6","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"9.9","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"9.1","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.1","Tissue RNA - white matter [nTPM]":"10.4","Cell RNA - A-431 [nTPM]":"21.4","Cell RNA - A549 [nTPM]":"21.0","Cell RNA - AF22 [nTPM]":"17.2","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"48.5","Cell RNA - ASC TERT1 [nTPM]":"36.2","Cell RNA - BEWO [nTPM]":"20.9","Cell RNA - BJ [nTPM]":"26.4","Cell RNA - BJ hTERT+ [nTPM]":"36.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"11.6","Cell RNA - Daudi [nTPM]":"46.4","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"30.8","Cell RNA - GAMG [nTPM]":"42.5","Cell RNA - HaCaT [nTPM]":"35.1","Cell RNA - HAP1 [nTPM]":"23.3","Cell RNA - HBEC3-KT [nTPM]":"19.5","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"13.7","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"15.4","Cell RNA - HHSteC [nTPM]":"44.0","Cell RNA - HL-60 [nTPM]":"38.8","Cell RNA - HMC-1 [nTPM]":"27.6","Cell RNA - HSkMC [nTPM]":"33.9","Cell RNA - hTCEpi [nTPM]":"22.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"42.6","Cell RNA - Karpas-707 [nTPM]":"34.5","Cell RNA - LHCN-M2 [nTPM]":"30.4","Cell RNA - MCF7 [nTPM]":"33.7","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"29.4","Cell RNA - PC-3 [nTPM]":"12.8","Cell RNA - REH [nTPM]":"27.2","Cell RNA - RH-30 [nTPM]":"23.7","Cell RNA - RPMI-8226 [nTPM]":"22.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.0","Cell RNA - RT4 [nTPM]":"49.9","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"18.1","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"35.8","Cell RNA - SuSa [nTPM]":"30.1","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"41.6","Cell RNA - TIME [nTPM]":"20.7","Cell RNA - U-138 MG [nTPM]":"26.1","Cell RNA - U-2 OS [nTPM]":"12.4","Cell RNA - U-2197 [nTPM]":"122.4","Cell RNA - U-251 MG [nTPM]":"30.8","Cell RNA - U-266\/70 [nTPM]":"23.3","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"44.0","Cell RNA - U-87 MG [nTPM]":"28.4","Cell RNA - U-937 [nTPM]":"77.5","Cell RNA - WM-115 [nTPM]":"24.8","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"2.5","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"10.4","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.3","Single Cell Type RNA - Astrocytes [nTPM]":"73.1","Single Cell Type RNA - B-cells [nTPM]":"36.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"38.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"33.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.5","Single Cell Type RNA - Erythroid cells [nTPM]":"29.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"26.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.1","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"26.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"43.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.8","Single Cell Type RNA - Late spermatids [nTPM]":"26.0","Single Cell Type RNA - Leydig cells [nTPM]":"26.4","Single Cell Type RNA - Macrophages [nTPM]":"26.5","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"66.5","Single Cell Type RNA - monocytes [nTPM]":"24.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"80.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"13.9","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"23.1","Single Cell Type RNA - Spermatogonia [nTPM]":"23.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"34.5","Single Cell Type RNA - Theca cells [nTPM]":"22.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"}]