Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
AKT2	PKBβ	ENSG00000105221	"AKT serine/threonine kinase 2"	P31751	19	40230317-40285536	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"	"Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport"	"Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004204, HPA064521"	Uncertain		Supported	Nucleoplasm,Vesicles,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 52: Non-specific - Transcription"	"Nucleoplasm, Vesicles, Cytosol"		"CAB004204: AB_626659, HPA064521: AB_2685278"	"unprognostic (6.13e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.56e-1)"	"prognostic unfavorable (1.05e-6)"	"unprognostic (2.85e-1)"	"unprognostic (6.40e-3)"	"unprognostic (9.59e-2)"	"unprognostic (1.22e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.49e-2)"	"unprognostic (3.02e-1)"	"prognostic unfavorable (4.74e-4)"	"unprognostic (1.30e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.28e-1)"	"unprognostic (6.16e-2)"	"unprognostic (2.00e-1)"	62.8	40.0	31.7	37.3	31.3	48.4	38.6	58.3	40.0	49.8	55.1	42.3	24.5	43.5	49.4	42.5	46.1	25.1	40.8	31.5	24.5	52.2	59.2	30.7	38.1	32.0	26.0	53.9	41.9	58.5	47.8	27.6	26.3	41.2	23.3	41.2	32.5	45.0	101.3	39.4	35.6	34.2	22.1	38.1	33.1	29.7	28.0	53.4	100.1	118.7	37.0	39.8	41.5	35.2	66.2	160.1	63.1	61.5	72.0	88.9	32.5	41.7	63.5	87.6	77.9	71.8	60.8	67.4	36.8	96.3	37.2	28.2	66.8	90.0	56.1	62.5	74.3	43.4	116.5	44.7	45.8	50.7	50.5	82.7	53.6	58.6	56.4	71.9	19.0	73.0	57.3	67.5	49.8	54.6	81.1	24.7	31.7	73.7	41.5	54.2	32.1	48.5	68.3	105.7	82.7	49.8	43.3	75.0	35.0	62.5	59.8	64.9	18.8	52.7	51.5	47.3	67.6	61.5	59.0	56.4	52.6	59.7	44.3	5.7	2.6	2.1	2.2	1.2	2.2	1.9	1.8	1.5	1.7	2.9	1.7	2.6	4.0	1.7	1.6	4.9	1.6	1.7	31.7	31.3	58.3	40.0	31.5	24.5	32.0	26.0	26.3	22.1	28.0	35.2	18.1	16.0	15.9	51.2	33.0	23.8	23.9	20.9	26.2	67.6	25.3	23.9	31.2	30.0	18.1	60.7	41.7	31.3	26.0	23.7	21.5	19.7	5.5	26.2	26.7	17.4	19.2	19.1	30.4	30.4	25.2	27.9	20.9	25.8	14.0	44.2	13.9	87.5	22.3	60.6	25.3	20.1	22.4	23.2	17.5	10.5	42.9	20.0	23.2	23.4	21.7	46.2	50.4	41.7	40.6	24.8	16.9	26.7	30.4	29.7	21.8	24.8	24.9	97.4	19.7	29.3	25.0	14.8	15.6	31.1	27.4	38.7	23.1	56.9	23.3	29.4
ALK	CD246	ENSG00000171094	"ALK receptor tyrosine kinase"	Q9UM73	2	29192774-29921586	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"brain: 10.9"	"Group enriched"	"Detected in some"	5	"Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8"	"Group enriched"	"Detected in some"	5	"glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	6	"SH-SY5Y: 31.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA010694	Approved		Supported	"Plasma membrane"		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Plasma membrane"		"HPA010694: AB_1078133"	"unprognostic (4.96e-2)"	"unprognostic (1.11e-2)"	"unprognostic (1.45e-1)"	"unprognostic (4.56e-7)"	"unprognostic (7.17e-2)"	"unprognostic (1.71e-1)"	"unprognostic (9.07e-3)"	"unprognostic (6.29e-3)"	"unprognostic (1.18e-1)"	"unprognostic (1.01e-1)"	"unprognostic (2.67e-4)"	"unprognostic (3.70e-2)"	"unprognostic (2.06e-2)"	"unprognostic (7.15e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.38e-1)"	"unprognostic (3.61e-2)"	0.3	0.6	2.2	0.2	2.4	0.0	0.1	0.7	2.8	0.1	0.8	0.6	0.1	0.0	0.0	0.0	0.0	0.2	0.0	1.5	3.9	0.0	0.0	0.1	0.0	4.4	6.8	0.0	0.0	0.0	1.3	0.0	10.9	0.0	0.2	0.7	0.1	0.1	0.0	0.1	0.3	0.1	2.9	0.0	0.1	1.2	2.7	0.0	0.3	0.0	0.0	0.0	0.0	2.1	0.1	0.0	0.5	0.0	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	4.3	0.0	0.0	0.1	0.4	31.7	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	3.7	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	2.4	0.7	2.8	1.5	3.9	4.4	6.8	10.9	2.9	2.7	2.1	0.0	0.0	0.0	66.6	0.0	0.0	0.0	0.0	0.0	1.9	0.2	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	42.1	0.5	0.1	0.2	0.0	0.0	12.5	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	3.4	0.0	274.2	0.0	0.0	0.0	0.0	41.2	0.0	0.5	0.0	7.5	0.0	0.6	0.0	433.8	21.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.1	0.1	0.8	0.4	0.0	0.0	0.0	0.0	0.1	0.0	0.0
CCNE1	CCNE	ENSG00000105173	"Cyclin E1"	P24864	19	29811991-29824312	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Cell division"	Cyclin	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 35.8;placenta: 30.8"	"Cell type enriched"	"Detected in many"	14	"Extravillous trophoblasts: 1756.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in all"		"BEWO: 293.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000308, CAB016682, HPA018169"	Approved		Enhanced	Nucleoplasm		Yes	Yes			"Cluster 43: B-cells - Humoral immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoplasm		"CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384"	"unprognostic (2.90e-3)"	"unprognostic (1.33e-2)"	"unprognostic (1.47e-3)"	"prognostic unfavorable (6.35e-6)"	"unprognostic (5.78e-2)"	"unprognostic (4.77e-2)"	"prognostic unfavorable (3.89e-5)"	"unprognostic (1.26e-3)"	"unprognostic (3.14e-3)"	"prognostic unfavorable (2.97e-4)"	"unprognostic (3.29e-2)"	"unprognostic (7.07e-2)"	"unprognostic (1.11e-16)"	"unprognostic (5.61e-2)"	"unprognostic (1.92e-1)"	"unprognostic (6.63e-2)"	"unprognostic (1.46e-1)"	1.2	5.7	1.9	4.3	2.1	35.8	0.8	2.8	2.7	1.0	0.9	3.9	3.0	1.4	0.6	4.4	0.9	1.0	2.3	2.0	2.5	1.0	0.7	1.1	6.1	2.0	2.1	0.8	1.8	2.8	0.9	30.8	2.0	1.0	4.7	2.0	1.5	1.4	2.1	4.1	2.5	2.2	1.7	4.2	2.1	12.1	2.5	4.5	1.6	1.8	7.8	3.0	1.8	2.3	15.6	31.8	24.3	34.0	5.2	6.0	293.1	24.7	5.3	10.8	13.2	33.0	31.2	13.3	55.9	11.1	14.0	4.9	28.8	12.8	15.2	41.9	17.7	11.2	30.0	34.5	4.1	44.0	28.7	6.2	7.1	14.8	1.9	3.4	13.3	13.2	45.6	5.8	16.8	24.4	24.5	13.0	40.1	36.2	7.2	36.2	28.6	10.1	8.4	24.6	20.5	17.4	35.4	42.7	3.9	35.4	9.5	32.7	8.0	25.0	92.8	14.9	16.9	24.1	18.2	91.6	13.8	5.6	13.7	0.0	0.0	0.0	0.1	0.5	0.3	0.6	0.1	0.0	0.4	0.0	0.0	0.2	0.4	0.0	0.5	0.0	0.3	0.1	1.9	2.1	2.8	2.7	2.0	2.5	2.0	2.1	2.0	1.7	2.5	2.3	3.1	0.0	0.6	0.7	4.8	4.8	1.5	0.3	2.2	2.9	8.2	11.3	3.1	0.0	1.4	0.0	0.0	122.4	3.7	3.5	0.0	0.4	14.6	7.5	4.1	1.9	3.0	30.7	2.9	0.7	1756.5	6.0	5.6	20.1	0.0	4.6	1.4	0.2	43.4	3.3	5.1	3.3	0.0	1.0	2.5	3.6	1.2	4.2	1.8	0.0	0.2	1.7	0.0	2.5	1.3	1.4	2.2	2.2	18.4	2.2	1.0	0.4	0.1	1.1	6.6	4.1	3.4	25.0	17.6	8.5	6.0	115.7	4.5	6.9	4.9	3.5
DROSHA	"Etohi2, HSA242976, RN3, RNASE3L, RNASEN"	ENSG00000113360	"Drosha ribonuclease III"	Q9NRR4	5	31400494-31532196	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Ribosome biogenesis, RNA-mediated gene silencing"	"Endonuclease, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocyte precursor cells: 74.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031150			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 20: HeLa - Mitochondria"	"Cluster 68: Oligodendrocytes - Mixed function"	Nucleoplasm	Cytosol	"HPA031150: AB_2673761"	"unprognostic (8.37e-3)"	"unprognostic (1.81e-1)"	"unprognostic (9.56e-2)"	"prognostic unfavorable (6.79e-4)"	"unprognostic (5.40e-2)"	"unprognostic (6.03e-2)"	"prognostic unfavorable (1.39e-4)"	"unprognostic (3.11e-1)"	"unprognostic (4.08e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.86e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.39e-1)"	"unprognostic (6.94e-2)"	"unprognostic (2.32e-2)"	12.3	11.3	2.6	15.9	3.8	11.6	11.5	9.4	8.0	13.3	4.2	13.8	13.6	15.9	20.4	11.4	14.5	11.7	13.0	2.0	8.1	12.3	9.7	10.9	16.0	1.1	2.9	20.5	14.4	15.2	4.5	13.8	2.3	13.6	15.6	27.2	12.5	13.2	22.2	13.5	12.2	13.8	0.2	12.5	13.2	11.1	5.2	24.5	15.5	19.6	17.1	12.2	3.9	4.9	38.7	47.3	51.8	70.8	27.0	32.8	74.2	50.0	24.4	45.6	33.9	50.6	49.0	43.3	55.9	36.9	52.7	33.0	63.5	37.8	50.4	40.9	44.6	52.9	157.8	37.0	24.3	59.2	151.6	25.8	26.0	50.7	24.2	34.6	39.5	45.3	68.9	19.7	40.5	38.5	58.3	44.8	49.1	31.2	37.9	52.2	98.9	31.1	25.7	43.2	26.9	35.6	127.1	51.4	30.0	46.0	47.4	34.1	33.9	43.7	50.3	39.0	48.0	35.8	63.5	47.1	30.3	65.9	42.9	0.9	1.2	1.5	2.2	1.3	2.4	1.8	2.4	2.7	2.5	2.0	2.7	2.0	0.3	2.5	2.5	3.0	2.5	1.6	2.6	3.8	9.4	8.0	2.0	8.1	1.1	2.9	2.3	0.2	5.2	4.9	6.2	12.8	14.3	45.4	7.1	3.6	5.0	7.0	10.8	19.4	7.1	6.0	23.4	5.7	12.8	5.5	0.0	8.5	11.4	12.9	3.9	7.8	3.5	12.3	11.6	9.0	11.4	8.0	43.4	8.1	7.6	12.7	8.6	13.6	9.5	20.4	10.0	7.2	7.8	6.7	45.8	8.5	14.2	6.3	3.0	8.2	10.8	6.0	1.8	34.7	8.4	10.2	9.2	74.9	43.9	9.3	10.2	13.2	8.8	6.1	7.3	5.1	16.8	18.8	6.6	10.4	11.6	7.1	10.9	8.8	3.4	4.9	8.3	13.9	11.7	5.9
EGFR	"ERBB, ERBB1"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019017-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8"	"Cancer enhanced"	"Detected in all"		"glioma: 136.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in many"	13	"A-431: 5282.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534"	Enhanced		Enhanced	"Plasma membrane,Cell Junctions"	"Secreted to blood"	NA	NA	4740000	88000000		"Cluster 31: Skin - Epidermis development"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane, Cell Junctions"		"CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044"	"unprognostic (2.62e-2)"	"unprognostic (9.56e-3)"	"unprognostic (1.59e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.27e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.88e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.30e-3)"	"unprognostic (1.78e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.93e-3)"	"unprognostic (6.98e-3)"	"unprognostic (1.72e-1)"	"unprognostic (6.62e-2)"	"prognostic unfavorable (2.04e-5)"	27.9	11.4	12.6	4.0	18.3	0.0	20.0	16.6	9.7	20.4	10.5	12.2	5.7	11.4	10.3	23.5	13.9	9.0	7.1	6.3	10.3	11.6	35.3	14.9	2.5	10.4	19.0	15.1	15.8	3.5	2.9	67.9	8.9	16.2	10.7	10.2	22.1	15.0	10.9	51.0	9.5	9.3	7.5	5.1	11.1	4.2	22.6	12.8	20.6	20.6	8.3	14.7	24.1	6.3	5282.1	61.9	16.5	22.4	102.7	63.5	16.7	47.9	68.7	30.8	23.8	11.5	54.2	2.7	11.4	43.8	130.7	197.1	0.4	230.2	37.1	2.2	3.6	0.1	27.3	3.4	27.0	0.0	0.2	31.2	205.4	74.1	409.9	45.5	4.0	0.0	0.0	0.5	68.0	3.0	0.1	0.1	5.1	21.2	30.4	0.1	9.1	0.2	38.1	52.6	0.8	20.0	42.7	50.6	9.3	16.8	4.9	12.0	15.6	27.1	7.2	215.7	45.8	0.1	4.8	3.1	37.9	1.6	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.6	18.3	16.6	9.7	6.3	10.3	10.4	19.0	8.9	7.5	22.6	6.3	16.4	96.1	49.9	147.6	1.2	85.8	77.1	101.5	116.1	3.5	12.1	30.4	11.1	47.1	50.6	22.0	6.2	287.9	0.0	45.9	0.0	32.9	4.9	25.9	57.2	12.5	4.2	8.0	1.2	24.3	37.1	91.6	22.4	39.8	0.0	50.6	6.8	79.5	28.3	0.0	107.5	21.6	48.8	7.7	11.6	5.8	128.3	1.9	17.8	40.3	1.6	90.0	0.0	63.3	1.4	54.8	19.9	133.5	0.0	75.4	14.1	13.4	21.7	3.8	78.9	251.2	34.7	2.4	2.5	73.3	89.9	376.8	2.2	41.9	24.9	55.8
ERBB2	"CD340, HER-2, HER2, NEU, NGL"	ENSG00000141736	"Erb-b2 receptor tyrosine kinase 2"	P04626	17	39687914-39730426	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Transcription, Transcription regulation"	"Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"gdT-cell: 5.0"	"Lineage enriched"	"Detected in many"	4	"T-cells: 5.0"	"Group enriched"	"Detected in many"	41	"OE19: 6565.0;SK-BR-3: 3115.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555"	Enhanced		Enhanced	"Plasma membrane,Cytosol"		NA	NA		980000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane"	Cytosol	"CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500"	"unprognostic (1.97e-1)"	"unprognostic (6.60e-3)"	"unprognostic (6.21e-2)"	"prognostic unfavorable (8.99e-8)"	"unprognostic (2.96e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.97e-2)"	"unprognostic (9.04e-2)"	"unprognostic (1.79e-2)"	"unprognostic (1.20e-3)"	"prognostic unfavorable (9.17e-4)"	"unprognostic (3.92e-1)"	"prognostic favorable (2.41e-14)"	"unprognostic (9.29e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.75e-2)"	"unprognostic (1.96e-1)"	13.0	5.4	16.1	12.1	20.5	1.6	56.0	14.3	13.1	37.6	23.3	68.2	63.6	25.2	26.6	102.4	64.2	31.0	57.0	13.3	16.0	73.5	31.1	36.2	4.8	22.4	22.7	23.9	37.6	81.7	17.3	27.0	17.1	55.6	48.5	8.1	68.7	50.5	20.7	91.0	67.3	25.0	18.5	6.9	49.7	11.7	15.4	7.4	56.5	15.0	28.0	40.0	52.9	16.4	38.7	45.7	50.4	31.7	59.3	41.2	67.7	27.2	44.9	58.6	48.9	34.4	102.7	2.9	54.6	62.7	31.5	117.6	2.8	61.2	26.9	5.2	38.6	1.8	36.0	56.3	35.3	0.9	1.0	41.0	56.6	36.2	21.9	56.2	24.4	1.9	6.2	2.4	43.3	59.4	7.1	3.0	90.7	6565.0	11.7	3.9	20.5	5.4	58.9	118.9	9.4	2.6	51.5	3115.9	16.9	62.2	88.1	2.2	2.9	30.2	37.7	37.7	17.6	5.3	3.3	3.6	3.0	0.9	98.5	1.1	0.2	0.4	5.0	0.1	0.3	0.6	0.2	1.4	0.2	0.6	0.5	1.4	1.2	0.4	0.1	0.1	0.2	1.7	16.1	20.5	14.3	13.1	13.3	16.0	22.4	22.7	17.1	18.5	15.4	16.4	3.9	41.7	40.1	12.7	2.2	14.0	19.0	37.1	17.6	4.6	62.7	34.9	20.7	32.9	43.8	136.1	12.5	12.0	5.1	111.0	7.9	30.9	0.3	48.7	13.9	6.1	15.6	1.3	0.9	25.5	84.8	15.7	53.5	61.3	0.0	20.3	11.7	10.7	4.0	6.7	1.0	47.5	42.7	2.2	3.1	1.0	18.3	1.7	10.6	1.0	1.2	24.1	26.8	2.0	1.0	32.5	54.8	23.0	1.1	34.9	121.7	19.5	42.0	5.8	0.0	13.1	12.7	6.8	5.7	43.5	18.9	22.7	2.8	4.4	75.4	31.3
ERG	"erg-3, p55"	ENSG00000157554	"ETS transcription factor ERG"	P11308	21	38380027-38661780	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1"	"Cancer enriched"	"Detected in all"	4	"prostate cancer: 18.6"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018377, HPA046598"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA				"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Nucleoplasm	Cytosol	"CAB018377: AB_675518, HPA046598: AB_2679715"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.18e-6)"	"unprognostic (6.44e-3)"	"unprognostic (8.64e-3)"	"unprognostic (5.65e-2)"	"unprognostic (1.91e-1)"	"unprognostic (9.03e-4)"	"unprognostic (4.30e-2)"	"unprognostic (2.63e-2)"	"unprognostic (1.29e-1)"	"unprognostic (3.42e-2)"	"unprognostic (2.89e-1)"	"prognostic unfavorable (3.94e-4)"	"unprognostic (4.31e-3)"	"unprognostic (3.88e-2)"	"unprognostic (2.64e-2)"	"unprognostic (5.63e-3)"	24.6	4.1	5.1	7.1	5.5	7.6	20.0	5.0	5.5	10.0	3.0	5.4	3.4	11.6	1.9	5.2	9.1	12.0	12.4	4.5	5.1	12.8	6.1	19.6	7.5	5.9	5.4	4.4	4.9	2.4	2.4	24.3	6.2	7.1	3.4	0.5	3.7	4.3	7.9	4.9	6.5	12.0	4.7	26.6	4.6	1.5	7.0	4.1	10.0	9.9	3.7	9.2	6.9	5.4	0.0	0.0	1.5	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	1.6	0.0	0.0	0.2	22.3	0.0	0.1	0.9	0.0	0.0	138.3	0.1	0.0	0.0	0.0	1.0	47.7	0.0	0.5	0.0	0.0	151.5	0.0	0.0	0.0	0.1	0.1	0.0	1.1	0.2	0.0	0.0	0.0	0.0	113.4	0.7	2.2	0.5	0.0	0.0	0.0	0.0	0.7	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	5.1	5.5	5.0	5.5	4.5	5.1	5.9	5.4	6.2	4.7	7.0	5.4	94.4	0.0	3.9	0.3	0.7	3.4	1.7	0.6	3.4	0.0	0.6	4.3	3.8	4.3	1.3	0.0	0.0	0.0	0.1	0.1	0.0	0.1	0.7	0.7	0.4	105.5	0.0	13.5	13.3	0.0	0.0	5.7	0.0	2.1	24.0	4.4	69.9	1.3	0.3	0.0	1.7	0.4	0.0	5.9	3.4	2.1	0.9	0.9	3.6	88.1	0.2	0.0	0.0	7.1	1.4	0.0	0.0	0.0	1.5	1.4	0.0	0.0	0.0	0.1	0.0	2.4	3.7	0.3	1.4	0.5	3.4	0.0	0.6	0.5	0.3	0.6
FLT4	"PCL, VEGFR-3, VEGFR3"	ENSG00000037280	"Fms related receptor tyrosine kinase 4"	P35916	5	180601506-180649624	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	Angiogenesis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in some"	7	"Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in single"	4	"MAIT T-cell: 3.8"	"Lineage enriched"	"Detected in single"	31	"T-cells: 3.8"	"Cell line enhanced"	"Detected in some"		"AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000099, HPA046519, HPA067906, HPA074389"	Approved		Supported	"Nuclear speckles,Plasma membrane,Cell Junctions"	"Secreted to blood"	NA	NA	20000000	290000000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 6: T47d - Mammary gland"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	"Nuclear speckles, Plasma membrane"	"Cell Junctions"	"CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: "	"unprognostic (7.35e-2)"	"unprognostic (1.63e-1)"	"unprognostic (9.45e-3)"	"unprognostic (3.81e-1)"	"unprognostic (9.26e-2)"	"unprognostic (3.20e-3)"	"unprognostic (1.13e-2)"	"unprognostic (1.80e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.70e-1)"	"unprognostic (2.13e-2)"	"unprognostic (3.69e-1)"	"unprognostic (1.88e-2)"	"unprognostic (9.41e-3)"	"unprognostic (1.83e-1)"	"unprognostic (8.26e-2)"	"unprognostic (1.32e-1)"	17.2	11.3	3.5	4.7	4.6	0.8	14.7	2.6	3.4	9.0	2.6	4.9	2.8	8.0	3.0	4.4	9.8	3.8	9.7	5.1	2.6	20.1	6.2	16.9	5.5	3.4	3.0	4.5	2.0	2.3	7.8	6.4	3.6	5.6	1.3	0.3	2.0	2.5	4.7	4.0	7.2	4.1	2.8	17.6	3.5	3.1	4.2	1.0	25.7	4.1	1.4	5.6	5.5	2.7	0.1	2.5	3.2	10.1	0.0	0.0	12.4	0.3	0.1	0.0	0.0	0.4	0.3	0.3	0.9	0.1	0.6	0.4	3.4	0.2	0.3	0.1	15.6	1.2	0.5	0.5	0.1	9.5	0.3	0.2	0.1	0.2	0.4	0.3	9.9	12.3	0.4	0.4	2.1	5.6	0.1	0.5	7.0	0.3	0.6	8.2	0.1	0.1	0.1	0.3	0.3	1.1	0.1	0.2	0.1	3.1	14.6	0.3	15.7	0.2	6.9	0.2	0.1	0.2	0.1	0.1	0.1	0.2	0.1	0.1	0.0	0.0	0.5	0.0	3.8	0.0	0.2	0.8	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.1	3.5	4.6	2.6	3.4	5.1	2.6	3.4	3.0	3.6	2.8	4.2	2.7	27.4	0.0	1.7	0.7	0.7	0.9	0.2	0.0	1.2	0.2	1.4	1.4	4.5	0.0	0.6	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.4	0.1	0.1	27.1	0.0	0.0	0.2	0.0	37.1	0.8	0.0	0.1	2.5	2.4	64.6	0.6	1.2	0.0	0.1	0.0	0.0	3.3	0.8	0.7	0.3	0.6	0.0	3.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.8	0.0	0.2	0.0	0.7	0.7	0.1	5.2	0.1	1.1	1.0	1.8	0.2	0.0	0.1
JUN	"AP-1, c-Jun"	ENSG00000177606	"Jun proto-oncogene, AP-1 transcription factor subunit"	P05412	1	58776845-58784048	"Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"RH-30: 295.6"	"Low region specificity"	"Detected in all"							"CAB003801, CAB007780, HPA031174, HPA059474"	Enhanced		Enhanced	Nucleoplasm		Yes	No			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm		"CAB003801: AB_365485, CAB007780: AB_562268, HPA031174: , HPA059474: AB_2684030"	"unprognostic (2.06e-2)"	"unprognostic (1.76e-2)"	"unprognostic (1.34e-1)"	"unprognostic (7.85e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.70e-1)"	"unprognostic (4.11e-2)"	"unprognostic (5.21e-2)"	"unprognostic (1.24e-1)"	"unprognostic (5.00e-2)"	"unprognostic (2.14e-1)"	"unprognostic (2.82e-1)"	"unprognostic (5.15e-2)"	"unprognostic (1.45e-1)"	"unprognostic (2.83e-1)"	"unprognostic (2.37e-1)"	"unprognostic (2.81e-3)"	331.1	92.7	34.4	36.3	37.0	129.1	308.2	41.6	38.1	172.0	28.0	154.7	34.7	116.4	15.8	100.2	314.1	89.6	158.4	39.1	37.2	94.0	205.2	202.8	52.1	32.7	30.7	197.0	192.2	59.8	75.0	40.1	30.5	153.4	55.0	29.7	154.5	71.7	114.3	286.6	79.1	113.3	34.3	62.0	239.5	20.2	33.8	71.5	189.5	158.8	5.4	156.4	164.5	36.9	49.8	2.8	22.4	2.6	35.3	40.0	0.2	69.4	27.0	57.1	34.3	10.1	3.5	1.7	23.8	57.4	133.6	12.9	2.0	27.7	40.6	29.8	128.9	0.5	1.9	16.9	29.4	5.3	10.2	42.0	74.0	78.1	34.0	27.7	47.2	2.4	15.6	29.6	24.9	8.0	2.5	32.5	13.5	34.6	32.2	1.1	295.6	7.0	60.7	5.8	43.7	12.8	49.9	62.3	26.4	24.5	17.2	3.0	61.6	127.5	37.3	35.3	96.8	37.9	9.8	4.4	133.9	8.4	35.2	0.0	0.2	0.0	0.2	0.0	0.0	0.3	0.2	0.0	0.0	0.6	0.0	0.1	0.2	0.6	0.0	0.0	0.0	0.0	34.4	37.0	41.6	38.1	39.1	37.2	32.7	30.7	30.5	34.3	33.8	36.9	2721.4	538.5	543.8	187.7	1018.8	1235.5	2850.5	772.6	2825.1	103.4	1647.1	2067.3	1487.5	1315.4	449.3	104.8	262.7	675.8	651.1	1653.6	50.9	987.0	49.3	1337.1	2845.2	1443.8	1497.4	174.3	12.2	516.4	93.9	2730.7	2663.1	1822.2	541.9	333.4	737.2	158.6	650.5	87.5	4.9	1909.1	836.2	584.9	632.0	48.2	1227.4	1034.9	757.7	65.6	140.1	1234.2	8.2	17.6	10.0	562.8	1529.6	258.8	1540.3	1489.1	1654.1	48.6	216.3	453.5	1538.3	1892.9	2392.5	17.4	20.9	2146.3	964.4	415.6	1065.5	846.5	1199.5	545.7
KAT6A	"MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220"	ENSG00000083168	"Lysine acetyltransferase 6A"	Q92794	8	41929479-42051994	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase"	"Cancer-related genes, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017023, HPA063266, HPA065052"	Supported		Supported	"Nucleoli,Nuclear speckles,Cytosol"		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Nuclear speckles"	"Nucleoli, Cytosol"	"CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414"	"unprognostic (3.51e-2)"	"unprognostic (1.14e-1)"	"unprognostic (2.04e-1)"	"unprognostic (3.23e-2)"	"unprognostic (2.28e-1)"	"unprognostic (9.27e-3)"	"unprognostic (3.61e-1)"	"unprognostic (2.29e-1)"	"unprognostic (2.95e-1)"	"unprognostic (2.45e-2)"	"unprognostic (1.50e-1)"	"unprognostic (4.45e-2)"	"unprognostic (4.20e-3)"	"unprognostic (1.18e-1)"	"unprognostic (2.24e-1)"	"unprognostic (8.58e-2)"	"unprognostic (2.95e-2)"	14.4	7.1	8.6	15.4	12.7	38.2	12.3	20.1	10.5	13.7	9.7	10.2	9.6	15.6	8.6	13.4	12.0	11.2	9.1	9.1	12.8	9.1	10.0	16.7	16.8	12.7	12.4	21.5	11.7	18.0	6.7	14.9	12.9	11.0	10.6	18.1	9.6	9.7	13.1	16.6	12.1	13.5	8.2	15.7	11.3	11.4	10.1	27.0	14.2	16.0	17.2	12.0	10.7	16.7	19.6	23.2	34.8	21.8	17.8	20.3	9.8	15.4	20.6	17.9	14.2	16.3	11.5	33.4	13.4	19.0	19.5	17.3	27.3	18.6	23.2	16.1	14.4	60.4	14.2	10.3	14.8	27.3	23.6	17.1	19.1	20.4	24.8	14.5	18.8	29.7	36.6	24.2	16.0	10.4	59.9	9.4	12.8	20.4	8.1	37.7	39.1	9.9	11.0	27.1	17.6	16.7	15.8	12.4	13.8	15.8	26.3	12.9	25.5	21.6	15.3	21.1	15.5	16.8	22.1	33.8	12.6	14.1	17.3	2.5	0.8	1.8	1.6	0.9	1.6	1.4	1.6	2.1	0.6	1.6	1.9	1.8	5.1	1.9	0.9	1.1	1.9	1.2	8.6	12.7	20.1	10.5	9.1	12.8	12.7	12.4	12.9	8.2	10.1	16.7	87.5	35.3	34.9	64.0	54.0	50.3	24.2	15.5	18.2	54.8	31.7	25.5	23.7	18.6	25.3	12.9	54.2	14.4	61.5	23.2	3.9	14.2	2.6	30.3	47.5	56.7	24.7	31.2	62.8	11.8	17.0	32.4	21.4	44.8	35.4	31.9	43.5	25.3	17.0	58.9	76.6	24.9	10.2	44.2	34.5	4.8	28.3	43.7	23.2	120.9	30.3	27.9	61.8	93.5	129.2	15.7	20.2	23.0	38.7	30.7	22.9	10.6	22.8	44.9	19.7	49.3	34.6	37.8	37.0	23.0	61.2	21.1	61.4	19.7	19.3	27.2
LMO1	"RBTN1, RHOM1, TTG1"	ENSG00000166407	"LIM domain only 1"	P25800	11	8224309-8268716	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 9.8;skeletal muscle: 29.3;tongue: 12.4"	"Cell type enhanced"	"Detected in some"		"Basal keratinocytes: 18.5;Distal tubular cells: 27.4;Early spermatids: 60.7;Horizontal cells: 40.4"	"Cancer enriched"	"Detected in many"	6	"glioma: 6.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HeLa: 33.8;SCLC-21H: 12.5;SH-SY5Y: 38.5;SiHa: 7.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA				"Cluster 80: Striated muscle - Unknown function"	"Cluster 20: HeLa - Mitochondria"	"Cluster 29: Early spermatids - Spermatogenesis"				"unprognostic (3.74e-3)"	"unprognostic (1.45e-1)"		"unprognostic (4.75e-6)"	"unprognostic (9.34e-2)"	"unprognostic (2.37e-1)"		"unprognostic (1.98e-1)"	"unprognostic (7.06e-3)"	"unprognostic (8.09e-2)"	"unprognostic (2.24e-1)"	"unprognostic (9.05e-2)"	"unprognostic (4.36e-12)"	"unprognostic (1.76e-2)"	"unprognostic (8.88e-2)"	"unprognostic (2.58e-2)"	"unprognostic (3.13e-2)"	0.1	1.2	2.4	0.1	2.3	0.0	0.3	4.1	3.4	0.0	1.1	0.2	0.2	0.1	1.6	0.3	0.1	0.0	1.1	3.2	3.2	3.5	0.0	0.0	0.0	5.3	9.8	0.1	0.8	0.0	2.3	0.1	5.2	0.1	0.0	2.0	0.3	0.0	29.3	7.3	0.0	0.2	1.9	0.5	0.7	2.2	5.3	0.0	0.1	12.4	0.0	0.3	0.1	2.4	0.1	0.9	1.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	2.1	0.1	0.5	0.0	0.0	0.0	1.5	0.0	33.8	0.0	0.0	0.0	0.7	0.0	0.3	0.0	0.0	0.3	0.0	4.3	0.0	0.0	0.0	0.6	1.4	0.0	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	12.5	38.5	7.9	4.4	0.2	1.5	0.0	0.0	0.0	0.0	1.0	0.0	0.4	0.1	0.0	0.0	1.6	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	2.3	4.1	3.4	3.2	3.2	5.3	9.8	5.2	1.9	5.3	2.4	0.1	0.0	0.0	3.3	0.0	18.5	0.1	0.3	1.8	7.1	0.0	0.0	3.0	0.0	0.2	0.0	0.0	0.2	0.0	0.4	27.4	0.1	60.7	0.1	0.1	0.4	0.0	0.0	1.1	1.2	8.4	0.1	0.0	0.5	1.3	0.2	0.0	0.0	0.2	40.4	0.6	0.0	0.0	0.0	0.4	6.8	0.0	0.2	0.0	11.2	0.0	0.5	0.0	3.0	0.3	2.0	1.1	0.4	0.1	0.1	0.0	0.2	2.3	4.0	0.0	0.5	0.7	0.6	1.3	0.3	3.4	0.3	0.0	0.0	0.0	0.0
MDM2	"HDM2, MGC5370"	ENSG00000135679	"MDM2 proto-oncogene"	Q00987	12	68808177-68850686	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction, Ubl conjugation pathway"	Transferase	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Endometrial ciliated cells: 257.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HBEC3-KT: 504.6;U-698: 517.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000086, CAB016303, CAB079977"	Supported		Supported	"Nucleoplasm,Golgi apparatus,Cytosol"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 49: Ciliated cells - Cilium organization"	"Nucleoplasm, Cytosol"	"Golgi apparatus"	"CAB000086: AB_563872, CAB016303: AB_627920, CAB079977: "	"unprognostic (1.16e-1)"	"prognostic favorable (3.23e-4)"	"unprognostic (6.16e-2)"	"prognostic favorable (4.51e-7)"	"unprognostic (7.25e-2)"	"unprognostic (6.91e-2)"	"unprognostic (3.77e-2)"	"unprognostic (1.72e-1)"	"unprognostic (2.45e-2)"	"unprognostic (3.23e-1)"	"unprognostic (1.80e-3)"	"unprognostic (2.36e-1)"	"unprognostic (4.22e-2)"	"unprognostic (4.59e-2)"	"unprognostic (1.81e-1)"	"unprognostic (2.68e-1)"	"unprognostic (8.95e-2)"	14.0	11.6	5.4	10.4	10.0	28.6	11.9	7.4	7.6	13.9	28.0	20.7	6.4	9.5	7.1	13.0	14.1	12.0	6.8	3.8	7.4	9.5	26.9	14.3	13.8	9.9	8.5	10.8	14.3	10.9	5.0	16.4	9.2	11.3	21.9	14.2	9.6	11.5	18.6	10.9	7.5	12.4	6.0	11.4	10.0	6.6	9.2	15.6	15.4	12.9	17.0	15.1	10.8	12.8	18.7	42.1	43.5	22.6	55.9	51.5	223.4	49.7	50.3	26.2	41.5	26.8	8.4	188.6	13.5	34.7	7.3	11.0	31.4	504.6	42.1	51.0	22.0	35.3	36.0	115.0	55.7	32.6	31.0	77.8	46.5	101.5	69.4	26.9	73.7	32.1	37.1	45.4	50.8	28.0	43.1	10.7	36.9	10.1	8.2	149.4	31.7	16.2	16.0	146.0	34.3	20.2	32.0	25.0	11.3	88.8	58.3	21.4	82.3	20.2	38.0	16.8	18.5	68.2	47.7	517.6	31.3	12.8	81.2	6.1	5.4	5.2	4.1	4.1	3.7	4.7	3.5	4.1	3.0	5.4	3.6	3.5	19.2	3.7	7.2	3.9	4.1	3.6	5.4	10.0	7.4	7.6	3.8	7.4	9.9	8.5	9.2	6.0	9.2	12.8	23.1	32.1	56.3	26.1	36.4	15.6	30.5	42.6	22.8	26.8	21.4	17.1	20.9	24.3	75.8	25.8	33.3	47.5	32.1	19.3	13.7	19.5	2.5	257.4	34.5	22.0	25.1	29.9	28.8	24.2	28.0	31.9	28.5	74.8	32.9	33.2	15.7	45.0	18.3	30.3	32.9	23.4	32.6	49.0	25.0	2.9	19.3	44.9	12.4	37.5	35.4	27.8	10.3	25.6	71.8	22.4	20.1	15.1	117.7	39.8	15.8	21.3	141.7	35.3	19.7	30.0	32.4	17.3	20.0	59.5	22.0	94.3	31.8	49.4	20.9	82.0
MDM4	"HDMX, MDMX"	ENSG00000198625	"MDM4 regulator of p53"	O15151	1	204516379-204558120	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 58.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA018919, HPA048821"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm		"HPA018919: AB_1853694, HPA048821: AB_2680531"	"unprognostic (4.63e-2)"	"unprognostic (3.73e-1)"	"unprognostic (6.38e-2)"	"unprognostic (1.50e-1)"	"unprognostic (3.84e-2)"	"unprognostic (1.68e-3)"	"unprognostic (2.33e-1)"	"unprognostic (1.29e-1)"	"unprognostic (1.51e-2)"	"unprognostic (2.34e-2)"	"unprognostic (1.17e-2)"	"prognostic unfavorable (9.87e-4)"	"prognostic unfavorable (7.06e-6)"	"unprognostic (1.20e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.49e-2)"	"prognostic favorable (2.49e-4)"	13.7	10.5	9.2	13.4	18.7	56.1	14.3	16.3	12.1	17.6	35.0	12.4	5.8	12.0	18.6	11.5	13.6	6.7	11.4	10.6	17.8	14.4	14.8	16.3	18.8	17.5	14.6	18.9	18.8	5.3	16.3	10.1	17.5	14.6	9.6	25.2	11.9	7.3	10.5	20.7	16.7	7.1	10.5	22.6	13.2	19.9	15.9	30.4	15.8	4.2	17.4	12.1	13.7	36.0	6.5	12.7	12.5	17.3	8.6	9.4	58.7	4.8	4.9	6.1	8.9	6.6	8.7	22.4	4.5	6.7	5.1	6.8	8.5	7.2	8.2	6.8	6.0	17.8	32.0	7.6	6.5	14.0	16.9	9.4	4.5	9.9	17.4	6.3	6.0	14.2	10.4	31.5	5.4	21.9	8.6	12.3	17.3	2.4	5.3	10.1	10.2	7.5	6.0	31.1	5.6	12.6	4.9	9.1	9.1	12.4	18.0	8.1	6.1	6.8	12.1	4.5	7.9	15.8	6.2	18.2	4.7	5.9	10.1	7.5	4.3	5.8	5.7	4.2	4.9	7.9	4.4	4.1	3.6	11.9	6.1	5.4	6.4	4.1	3.8	7.8	2.6	2.5	9.2	18.7	16.3	12.1	10.6	17.8	17.5	14.6	17.5	10.5	15.9	36.0	73.6	28.9	56.9	76.0	118.1	61.6	48.2	31.0	22.8	96.0	55.2	33.7	38.5	47.1	51.2	69.9	168.9	52.0	135.7	35.5	13.7	29.9	82.3	39.6	74.2	54.5	65.0	64.4	61.8	26.7	26.1	53.0	36.7	63.2	65.9	82.6	87.1	61.0	35.5	42.1	65.7	48.3	54.9	96.4	128.3	160.2	80.2	62.0	42.7	83.4	81.8	40.1	90.6	106.6	170.3	26.5	42.3	54.2	81.0	66.3	49.0	18.6	32.0	192.7	52.6	99.6	50.5	75.7	64.8	23.0	68.3	60.9	73.7	58.2	51.1	48.3
MITF	"bHLHe32, MI, WS2, WS2A"	ENSG00000187098	"Melanocyte inducing transcription factor"	O75030	3	69739464-69968336	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3"	"Cancer enriched"	"Detected in all"	4	"melanoma: 39.2"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9"	"Group enriched"	"Detected in many"	6	"dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4"	"Cell line enhanced"	"Detected in many"		"HMC-1: 89.1;SK-MEL-30: 254.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002578, HPA003259"	Enhanced					NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB002578: AB_564111, HPA003259: AB_1079381"	"unprognostic (3.29e-1)"	"unprognostic (4.26e-2)"	"unprognostic (2.98e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.75e-1)"	"unprognostic (5.31e-3)"	"unprognostic (3.87e-3)"	"unprognostic (1.94e-1)"	"prognostic favorable (8.35e-10)"	"unprognostic (6.37e-2)"	"unprognostic (1.08e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.73e-1)"	13.8	4.4	5.1	3.8	9.2	1.7	10.0	9.4	6.3	51.3	21.2	18.8	2.8	46.2	4.5	8.9	10.3	16.8	31.1	5.2	9.3	20.0	2.2	9.7	3.4	12.5	9.5	18.7	4.2	16.8	3.8	3.3	10.4	8.4	4.5	1.2	5.1	14.1	50.6	11.0	5.8	46.0	7.0	2.0	9.4	2.3	10.3	2.2	7.6	43.3	1.5	10.6	16.6	13.8	17.2	12.2	1.3	5.1	18.8	0.3	2.0	16.9	9.9	7.8	4.8	6.1	0.8	0.0	4.0	0.3	21.6	8.6	3.7	9.4	8.6	0.0	2.5	37.1	24.5	0.3	4.5	0.8	89.1	15.3	3.9	2.2	8.6	29.1	2.4	0.0	12.3	5.2	5.4	1.2	0.7	1.0	0.7	0.7	8.3	0.1	1.9	7.7	45.2	9.0	0.4	1.9	8.8	3.1	254.1	2.0	0.7	2.3	0.1	3.8	13.3	5.1	3.5	0.6	1.0	0.1	7.7	2.6	9.2	5.2	9.4	0.0	0.0	3.3	0.0	0.0	0.0	0.1	6.1	0.0	0.0	0.0	0.7	1.1	5.9	0.5	0.0	3.1	5.1	9.2	9.4	6.3	5.2	9.3	12.5	9.5	10.4	7.0	10.3	13.8	4.6	28.9	6.8	34.3	0.2	42.8	3.6	16.7	7.4	1.6	1.8	1.8	109.5	11.5	18.2	14.7	0.0	1.3	0.6	0.4	50.9	14.7	1.6	24.5	94.3	7.4	1.2	8.6	14.7	8.8	1.0	38.3	9.7	71.2	106.8	10.9	4.6	2.1	45.8	6.7	133.5	0.3	12.2	30.8	30.9	3.4	44.4	24.3	585.2	50.6	10.6	1.4	0.0	166.9	240.3	7.7	0.0	50.4	0.4	5.2	0.2	24.3	12.5	0.2	13.1	17.8	22.6	4.0	6.3	7.2	18.9	1.1	3.8	5.5	0.6	7.1
MYC	"bHLHe39, c-Myc, MYCC"	ENSG00000136997	"MYC proto-oncogene, bHLH transcription factor"	P01106	8	127735434-127742951	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 254.6;skin 1: 289.1"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPMI-8226: 1069.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000084, CAB010307, HPA055893, HPA066556"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 61: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691"	"unprognostic (1.45e-2)"	"unprognostic (4.00e-3)"	"unprognostic (3.94e-3)"	"unprognostic (2.41e-3)"	"unprognostic (8.14e-2)"	"unprognostic (3.36e-3)"	"unprognostic (5.80e-2)"	"unprognostic (4.94e-3)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (7.52e-4)"	"unprognostic (5.19e-3)"	"unprognostic (9.86e-3)"	"prognostic unfavorable (5.49e-8)"	"unprognostic (7.85e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.48e-1)"	"prognostic unfavorable (4.96e-5)"	254.6	59.8	2.6	62.3	2.2	53.7	115.8	3.7	3.3	54.4	3.0	57.9	30.6	53.8	3.8	99.5	167.5	83.3	45.5	2.3	6.3	20.0	64.9	47.0	49.4	9.2	5.0	100.0	103.1	7.0	12.3	33.4	6.0	32.7	36.8	0.7	42.2	14.1	50.6	289.1	48.6	54.8	4.5	60.1	70.6	12.5	5.5	47.2	27.0	15.7	39.2	63.2	96.3	4.4	56.8	89.3	9.3	100.9	166.6	209.8	28.4	72.2	31.6	87.5	72.7	137.0	150.2	587.3	86.4	43.0	82.4	122.2	383.8	226.5	67.8	128.9	167.0	370.7	189.5	203.6	150.0	282.0	52.0	138.8	560.4	55.5	490.8	74.8	104.3	217.3	549.8	315.5	49.7	151.9	394.4	616.9	27.4	273.2	204.0	203.7	46.1	1069.6	79.2	61.9	660.7	64.9	32.6	270.7	195.9	17.5	106.4	172.2	120.5	63.4	71.6	49.7	87.2	5.5	8.7	275.9	55.3	286.2	30.8	3.0	39.5	0.7	31.5	36.0	161.5	92.0	114.3	67.4	33.5	71.4	195.2	128.0	4.1	85.5	26.9	1.4	95.6	88.9	2.6	2.2	3.7	3.3	2.3	6.3	9.2	5.0	6.0	4.5	5.5	4.4	218.0	57.7	70.4	0.7	108.0	1013.3	1080.5	278.9	1270.8	0.6	251.3	207.3	10.9	44.3	98.4	12.9	0.0	20.6	20.9	23.0	1.9	78.3	1.0	43.9	224.5	158.0	12.5	189.1	1.6	43.6	61.2	337.9	46.4	72.0	57.0	47.6	141.0	25.8	26.9	0.0	1.1	67.8	97.6	43.7	133.1	3.9	98.8	23.3	168.9	1.0	17.0	1.4	5.2	0.0	0.2	66.5	40.4	67.4	45.7	364.8	4.8	13.3	21.5	0.3	46.0	458.5	349.1	0.6	0.6	768.8	1070.1	5.9	75.0	56.0	117.7	409.4
MYCL	"bHLHe38, LMYC, MYCL1"	ENSG00000116990	"MYCL proto-oncogene, bHLH transcription factor"	P12524	1	39895426-39902256	"Cancer-related genes, Predicted intracellular proteins, Transcription factors"		DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"pancreas: 67.8;skin 1: 41.5"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1"	"Cancer enhanced"	"Detected in all"		"urothelial cancer: 28.9"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	5	"classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8"	"Group enriched"	"Detected in many"	72	"dendritic cells: 22.8;monocytes: 17.3"	"Group enriched"	"Detected in many"	7	"U-266/70: 444.0;U-266/84: 364.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA063132, HPA074515"			Enhanced	"Nucleoplasm,Mitotic chromosome"		Yes	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 25: Pancreas - Digestion"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 61: Squamous epithelial cells - Keratinization"	Nucleoplasm	"Mitotic chromosome"	"HPA063132: AB_2684946, HPA074515: "	"unprognostic (7.45e-2)"	"unprognostic (6.91e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.83e-3)"	"unprognostic (1.61e-2)"	"unprognostic (2.92e-3)"	"unprognostic (6.72e-3)"	"prognostic favorable (4.49e-4)"	"unprognostic (1.24e-1)"	"unprognostic (1.77e-2)"	"unprognostic (5.44e-2)"	"unprognostic (1.12e-1)"	"unprognostic (5.01e-3)"	"unprognostic (2.75e-2)"	"unprognostic (5.21e-2)"	"unprognostic (1.53e-2)"	"unprognostic (5.80e-2)"	0.8	0.3	1.8	4.7	2.0	0.6	3.3	1.2	2.0	5.2	1.8	6.1	4.8	0.9	7.2	22.1	3.1	1.5	0.5	2.2	1.7	1.5	11.4	3.3	6.4	1.5	1.5	0.3	67.8	0.3	2.9	6.7	1.6	4.2	6.7	0.2	6.4	7.5	0.5	41.5	5.7	1.1	1.9	7.6	6.2	1.3	2.0	6.5	5.3	0.5	9.5	15.9	12.8	1.6	1.2	0.4	14.4	3.5	0.2	0.1	31.8	0.5	0.2	1.0	0.7	0.4	0.8	2.2	1.4	0.1	0.4	3.3	10.4	2.7	0.8	2.0	4.9	0.5	0.3	0.5	0.4	0.3	7.5	1.0	12.1	0.4	1.3	0.2	1.2	5.4	3.2	0.4	0.6	1.2	0.2	0.3	13.4	2.2	0.4	1.3	15.5	2.9	1.1	58.0	2.5	3.1	1.4	2.1	0.8	5.5	3.7	18.7	0.0	0.0	4.6	6.2	0.5	444.0	364.6	1.0	0.1	2.3	0.3	0.0	17.3	0.0	0.0	8.2	0.0	0.0	0.0	0.0	18.7	0.0	0.0	0.0	0.2	0.0	3.4	22.8	0.0	6.7	1.8	2.0	1.2	2.0	2.2	1.7	1.5	1.5	1.6	1.9	2.0	1.6	0.4	0.0	1.1	0.0	0.8	6.6	10.0	2.1	13.1	0.4	3.8	6.0	3.7	0.0	5.5	9.2	0.0	34.9	20.1	13.4	0.0	1.5	0.1	5.1	0.6	0.5	17.3	0.0	0.2	5.8	15.4	0.9	5.1	6.3	0.0	0.0	1.4	24.3	5.1	0.0	0.3	25.0	8.2	8.3	13.1	0.4	0.0	10.6	1.8	0.0	27.4	0.8	0.0	1.0	0.0	2.9	6.5	0.0	3.6	5.3	6.4	0.1	4.9	0.1	0.0	1.4	0.7	0.0	1.2	34.2	11.8	17.5	0.3	0.0	10.8	27.1
MYCN	"bHLHe37, MYCNOT, N-myc, NMYC"	ENSG00000134323	"MYCN proto-oncogene, bHLH transcription factor"	P04198	2	15940550-15947007	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 9.5"	"Group enriched"	"Detected in some"	4	"Extravillous trophoblasts: 84.2;Granulosa cells: 26.4"	"Cancer enriched"	"Detected in many"	5	"testis cancer: 45.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA057420			Approved	Nucleoplasm,Nucleoli		NA	NA				"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoli	Nucleoplasm	"HPA057420: AB_2683434"	"unprognostic (8.04e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.29e-1)"	"unprognostic (2.07e-2)"	"unprognostic (4.11e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.23e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.35e-3)"	"unprognostic (3.09e-2)"	"unprognostic (2.09e-1)"	"unprognostic (1.12e-3)"	"unprognostic (8.89e-2)"	"unprognostic (2.47e-1)"	"unprognostic (4.90e-2)"	"unprognostic (1.23e-1)"	0.4	0.8	3.5	0.6	3.5	0.9	0.4	3.1	3.9	1.5	0.8	0.6	1.6	0.9	0.1	0.7	0.5	0.3	1.2	3.4	3.0	3.3	0.8	0.7	1.6	4.4	3.9	5.1	0.2	0.1	0.3	9.5	3.7	0.1	0.5	1.0	4.7	0.2	0.4	1.4	0.9	0.3	3.3	0.3	4.6	3.6	3.5	2.9	2.9	0.7	1.2	0.5	0.4	5.9	0.0	0.0	44.1	0.0	0.0	0.0	239.1	0.0	0.0	0.0	0.0	3.5	0.0	0.0	4.2	0.0	0.0	0.1	1.9	0.0	0.0	0.0	0.2	16.8	0.0	0.0	0.0	0.0	57.3	0.0	0.0	0.0	0.0	0.0	0.2	0.7	0.0	0.1	0.0	0.8	0.4	0.2	91.3	2.1	0.0	0.0	63.3	12.8	0.0	3.1	1.0	16.0	0.0	0.1	0.0	40.9	0.1	0.0	0.0	0.0	1.2	0.0	0.0	2.9	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.5	3.5	3.1	3.9	3.4	3.0	4.4	3.9	3.7	3.3	3.5	5.9	0.8	0.0	0.0	0.7	0.0	0.5	0.1	0.0	0.0	2.6	0.1	0.9	0.7	0.0	0.0	0.0	0.0	5.6	0.0	0.2	0.0	0.0	1.2	0.5	0.1	2.7	0.0	4.2	2.0	0.0	84.2	1.0	2.6	0.8	0.0	26.4	0.0	0.6	2.4	0.0	4.2	0.9	0.0	0.0	0.0	0.2	0.0	0.3	0.0	1.0	0.1	1.0	0.0	10.1	7.5	0.3	1.1	0.4	0.0	0.0	0.4	3.2	0.0	0.2	0.0	4.2	0.7	1.3	3.7	0.3	0.0	11.5	0.0	9.4	0.3	0.0
NKX2-1	"BCH, NKX2A, TITF1, TTF-1, TTF1"	ENSG00000136352	"NK2 homeobox 1"	P43699	14	36516392-36521149	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Congenital hypothyroidism, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	6	"lung: 53.1;thyroid gland: 172.4"	"Group enriched"	"Detected in some"	5	"Alveolar cells type 1: 137.8;Alveolar cells type 2: 124.8"	"Group enriched"	"Detected in some"	39	"lung cancer: 30.9;thyroid cancer: 103.2"	"Region enhanced"	"Detected in many"		"thalamus: 17.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	11	"SCLC-21H: 78.7"	"Group enriched"	"Detected in some"	5	"basal ganglia: 3.2;hypothalamus: 10.2"	"Group enriched"	"Detected in some"	13	"basal ganglia: 4.3;hypothalamus: 10.4"	"CAB000078, CAB053633, HPA074316"	Enhanced		Uncertain	"Golgi apparatus,Vesicles"		NA	NA				"Cluster 1: Thyroid gland - Transcription"	"Cluster 7: SCLC-21H - Neuronal signaling"	"Cluster 11: Alveolar cells - Smell perception"	"Golgi apparatus, Vesicles"		"CAB000078: , CAB053633: AB_442138, HPA074316: "		"unprognostic (3.79e-1)"		"unprognostic (4.25e-3)"	"unprognostic (1.12e-1)"	"unprognostic (1.79e-2)"		"unprognostic (1.26e-2)"				"unprognostic (2.23e-1)"		"unprognostic (1.18e-1)"	"unprognostic (1.29e-1)"	"unprognostic (1.83e-2)"	"unprognostic (4.18e-1)"	0.0	0.1	1.1	0.0	2.0	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	10.1	0.0	0.0	53.1	0.0	0.0	0.3	0.1	0.1	0.0	12.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.1	17.8	0.0	172.4	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	1.2	0.0	0.0	0.0	2.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	78.7	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.2	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	2.0	0.0	4.0	0.1	10.1	0.0	0.3	0.0	0.0	17.8	0.1	0.0	137.8	124.8	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.6	0.0	25.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9	0.0	2.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	8.3	0.0	0.0	0.0	0.1	0.7	0.2	0.0	0.0	0.0	0.4	0.0	0.0	0.0
NSD3	"FLJ20353, KMT3F, WHISTLE, WHSC1L1"	ENSG00000147548	"Nuclear receptor binding SET domain protein 3"	Q9BZ95	8	38269704-38382272	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Methyltransferase, Transferase"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 173.8;Syncytiotrophoblasts: 130.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005659, CAB013721, HPA018893"	Uncertain		Approved	Nucleoplasm,Mitochondria		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 7: Non-specific - Mitochondria"	Mitochondria	Nucleoplasm	"CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833"	"unprognostic (6.21e-2)"	"unprognostic (3.73e-2)"	"unprognostic (2.18e-2)"	"unprognostic (4.12e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.53e-2)"	"unprognostic (4.35e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.49e-1)"	"unprognostic (5.72e-2)"	"prognostic unfavorable (7.48e-4)"	"unprognostic (5.06e-2)"	"unprognostic (5.60e-3)"	"unprognostic (6.69e-2)"	"unprognostic (4.04e-1)"	"unprognostic (1.05e-2)"	"unprognostic (1.60e-2)"	22.4	14.4	10.0	24.8	13.7	60.2	23.4	28.4	20.5	24.0	0.7	22.4	24.1	22.9	17.4	22.9	23.5	24.5	13.7	12.8	22.3	20.0	16.6	20.6	35.3	3.1	4.8	36.4	20.1	24.8	17.3	33.5	5.3	20.9	26.6	23.3	19.9	24.3	14.4	19.8	26.7	19.8	0.1	26.9	29.0	14.4	10.4	38.3	27.6	16.0	31.0	23.3	23.1	18.7	62.1	34.9	58.7	39.9	40.3	46.0	43.4	50.8	55.9	43.1	49.7	18.8	33.6	73.5	45.5	35.0	41.7	36.4	47.0	40.6	61.0	29.4	27.6	93.6	28.6	22.1	41.2	41.7	32.5	24.9	40.4	39.0	78.6	40.3	50.1	79.8	67.9	47.4	41.5	22.3	122.8	35.4	40.0	48.0	16.4	55.5	64.1	23.4	30.3	47.3	33.0	44.6	41.4	35.8	35.3	37.5	45.1	31.4	48.3	44.5	46.0	67.0	30.3	41.9	53.8	69.2	37.6	41.3	33.0	37.4	11.8	21.9	17.2	5.6	11.0	43.1	25.5	15.5	9.3	60.7	31.9	13.7	57.9	19.6	3.6	12.6	43.4	7.3	10.0	13.7	28.4	20.5	12.8	22.3	3.1	4.8	5.3	0.1	10.4	18.7	75.1	67.3	57.3	0.0	57.8	0.0	0.0	0.0	0.0	0.0	73.4	69.1	0.0	0.0	30.3	51.5	0.0	101.6	101.9	0.0	23.5	73.0	0.0	109.1	81.3	28.0	0.0	0.0	0.0	61.0	173.8	33.1	0.0	97.5	8.8	99.7	0.0	0.0	44.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	30.1	0.0	0.0	49.7	0.0	0.0	0.0	0.0	64.7	0.0	0.0	48.9	0.0	0.0	31.7	34.2	0.0	0.0	0.0	35.8	0.0	0.0	0.0	0.0	130.8	55.6	81.7	0.0	0.0
NTRK1	"MTC, TRK, TRKA"	ENSG00000198400	"Neurotrophic receptor tyrosine kinase 1"	P04629	1	156815640-156881850	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Differentiation, Neurogenesis"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"adrenal gland: 7.0;brain: 21.7"	"Group enriched"	"Detected in some"	10	"Bipolar cells: 22.8;granulocytes: 55.9;Horizontal cells: 57.2"	"Cancer enhanced"	"Detected in some"		"glioma: 1.3"	"Group enriched"	"Detected in many"	6	"cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7"	"Immune cell enriched"	"Detected in single"	116	"basophil: 94.5"	"Lineage enriched"	"Detected in single"	768	"granulocytes: 94.5"	"Cell line enriched"	"Detected in some"	4	"HMC-1: 82.1"	"Region enhanced"	"Detected in many"		"basal ganglia: 8.4"	"Region enriched"	"Detected in single"	6	"basal ganglia: 4.1"	"CAB004606, HPA035799, HPA076570"	Approved		Approved	Vesicles,Cytosol		NA	NA		79000	"Cluster 38: Basophils - Unknown function"	"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 62: Horizontal cells - Visual perception"	"Vesicles, Cytosol"		"CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: "	"unprognostic (5.89e-3)"	"unprognostic (7.56e-2)"	"unprognostic (2.74e-2)"	"unprognostic (5.99e-3)"	"unprognostic (7.26e-2)"	"unprognostic (1.43e-3)"	"unprognostic (1.56e-1)"	"unprognostic (7.42e-3)"	"unprognostic (7.63e-2)"	"unprognostic (1.35e-1)"	"unprognostic (6.73e-2)"	"unprognostic (2.29e-2)"	"unprognostic (3.18e-11)"	"unprognostic (2.18e-3)"	"unprognostic (3.79e-2)"	"unprognostic (1.07e-1)"	"unprognostic (4.89e-1)"	0.8	7.0	0.7	0.4	1.8	0.7	0.2	1.8	7.6	0.7	0.7	0.8	0.5	1.0	0.0	0.1	0.5	0.4	1.0	0.3	2.8	3.0	0.0	0.5	0.1	19.8	1.5	0.1	0.2	0.0	0.7	0.2	21.7	1.4	0.0	1.9	0.5	0.3	0.4	0.1	0.3	0.6	0.2	0.1	0.5	1.6	0.4	0.3	0.2	0.2	0.0	0.3	0.5	0.6	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.2	0.1	0.0	0.0	0.0	11.9	0.0	14.0	0.0	0.0	0.0	0.0	82.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	4.4	1.6	0.0	0.2	0.0	2.4	0.2	0.0	1.5	2.5	0.0	0.2	0.0	0.5	1.5	18.2	0.0	0.1	0.0	0.3	0.0	0.1	0.3	0.0	1.1	0.0	0.0	3.5	0.6	0.0	0.0	0.0	0.1	94.5	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.2	0.7	1.8	1.8	7.6	0.3	2.8	19.8	1.5	21.7	0.2	0.4	0.6	0.1	0.0	1.3	0.3	0.0	0.0	0.0	0.0	0.0	22.8	0.0	0.1	0.5	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	1.6	0.2	0.0	4.2	0.7	0.0	0.0	4.3	0.0	0.1	55.9	0.0	0.0	0.0	0.1	57.2	0.2	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	2.8	0.0	0.5	0.0	0.5	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	2.6	0.0	0.0	0.9	3.2	2.7	0.0	0.1	0.0	1.0	0.1	0.0	0.0
PPM1D	"PP2C-DELTA, Wip1"	ENSG00000170836	"Protein phosphatase, Mg2+/Mn2+ dependent 1D"	O15297	17	60600183-60666280	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 68.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MCF7: 34.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022277, HPA061848"	Approved		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm	Nucleoli	"HPA022277: AB_1858839, HPA061848: "	"unprognostic (1.48e-1)"	"unprognostic (1.36e-2)"	"prognostic favorable (3.52e-4)"	"unprognostic (1.76e-1)"	"unprognostic (1.02e-1)"	"unprognostic (5.12e-2)"	"prognostic unfavorable (4.27e-4)"	"unprognostic (5.50e-2)"	"unprognostic (1.70e-2)"	"unprognostic (6.07e-2)"	"unprognostic (2.52e-3)"	"unprognostic (3.46e-2)"	"unprognostic (1.95e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.71e-2)"	"unprognostic (1.98e-1)"	4.4	2.4	2.7	2.2	5.2	5.9	3.9	14.8	4.6	4.5	5.0	3.1	2.9	4.3	2.9	3.5	3.7	3.1	2.9	3.3	3.4	2.8	2.8	3.6	2.7	4.0	3.5	6.3	3.3	2.3	2.4	5.9	4.7	3.1	3.5	6.4	3.1	2.2	4.0	2.9	2.7	3.0	3.4	3.8	2.7	5.5	3.7	4.4	2.9	3.1	2.3	2.8	4.0	9.1	3.8	6.9	7.5	6.4	5.0	3.1	10.7	5.8	3.6	3.4	4.9	7.1	2.0	9.9	4.5	3.7	1.3	3.4	4.9	2.2	4.6	1.9	11.1	7.4	6.7	8.1	4.2	2.9	5.3	2.7	3.6	5.1	3.0	2.8	7.9	4.1	5.4	4.0	3.7	34.4	8.1	4.4	3.5	3.4	5.2	9.5	9.6	6.6	3.1	4.2	10.5	7.4	7.1	2.4	1.6	8.0	2.8	3.9	5.7	4.7	12.5	3.5	3.3	6.7	7.7	7.3	1.7	2.9	3.8	9.9	16.1	18.0	7.6	12.5	6.8	8.9	6.3	7.0	16.0	6.2	6.8	7.0	24.7	8.6	8.1	7.0	10.6	9.8	2.7	5.2	14.8	4.6	3.3	3.4	4.0	3.5	4.7	3.4	3.7	9.1	40.9	32.1	7.7	15.0	23.1	21.0	6.2	3.3	52.3	13.1	14.2	9.8	6.3	8.6	4.6	5.5	4.2	17.6	19.4	15.0	3.9	6.6	68.9	14.0	15.5	25.2	14.4	14.1	19.6	6.6	6.4	14.7	10.2	15.6	1.3	7.2	23.6	4.2	8.8	3.3	20.8	11.4	6.1	21.4	19.2	12.8	13.7	16.1	3.6	28.1	12.3	7.0	6.2	20.6	38.6	5.4	10.2	7.5	24.5	7.8	8.7	5.1	3.6	10.4	0.0	12.1	14.0	43.8	15.0	34.4	18.0	38.6	18.1	6.0	11.5	7.7
RAF1	"c-Raf, CRAF, Raf-1"	ENSG00000132155	"Raf-1 proto-oncogene, serine/threonine kinase"	P04049	3	12583601-12664125	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 175.1"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 175.1"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002639, HPA002640, CAB019291"	Approved		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 40: Granulosa cells - Unknown function"	"Plasma membrane, Cytosol"		"CAB019291: , HPA002639: , HPA002640: AB_1856047"	"unprognostic (6.33e-2)"	"unprognostic (1.29e-1)"	"unprognostic (5.92e-2)"	"unprognostic (2.17e-3)"	"unprognostic (6.51e-3)"	"unprognostic (7.66e-3)"	"unprognostic (2.66e-3)"	"unprognostic (1.53e-2)"	"unprognostic (2.72e-1)"	"unprognostic (7.66e-2)"	"unprognostic (2.92e-2)"	"unprognostic (1.29e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.79e-1)"	"unprognostic (1.27e-1)"	"unprognostic (2.64e-2)"	"unprognostic (2.36e-2)"	42.4	34.2	36.7	33.8	37.9	77.4	39.2	42.6	37.4	47.6	40.4	46.8	40.5	45.6	34.0	55.5	43.2	31.0	89.6	36.9	35.8	46.7	68.9	44.7	36.3	38.3	36.9	52.0	50.6	63.6	28.3	39.1	37.0	41.9	42.0	37.4	39.6	38.0	194.9	56.0	43.4	45.5	36.7	48.3	55.5	26.8	38.1	52.8	48.8	122.5	47.7	46.1	46.2	39.8	49.9	57.9	85.5	66.6	74.3	59.6	168.0	73.9	129.1	100.1	112.5	46.6	41.3	52.7	34.6	120.1	51.6	31.9	93.4	67.5	103.8	91.4	70.2	72.0	69.4	42.9	74.2	70.1	64.7	55.3	67.8	102.3	82.0	67.6	73.1	78.2	52.6	136.0	98.3	88.6	91.1	47.8	86.5	64.0	76.4	72.6	75.7	66.4	60.9	76.9	26.1	56.2	61.1	59.8	40.9	66.1	99.1	91.5	51.1	65.6	62.5	55.7	85.0	103.3	178.4	112.3	57.2	80.4	73.9	40.4	32.7	62.5	22.3	32.6	22.5	19.5	21.9	22.3	30.3	20.4	21.9	22.8	175.1	29.8	34.2	13.5	28.3	28.2	36.7	37.9	42.6	37.4	36.9	35.8	38.3	36.9	37.0	36.7	38.1	39.8	28.5	22.4	37.6	47.7	36.1	34.4	35.2	22.1	27.9	56.7	27.5	22.6	29.0	35.8	25.7	27.6	66.7	40.0	41.5	31.3	13.7	25.6	8.8	33.2	37.1	32.7	29.3	46.7	46.1	37.0	46.8	32.3	27.5	43.8	34.2	78.7	36.0	41.2	28.6	43.7	52.9	31.0	30.5	39.3	43.4	4.6	39.1	34.7	26.6	44.0	49.5	31.9	51.5	65.4	64.0	35.5	29.9	41.3	43.3	46.9	47.3	20.1	31.2	81.9	32.9	56.2	39.1	28.3	33.6	31.8	43.5	62.3	40.8	35.6	31.2	47.1
REL	"c-Rel, I-Rel"	ENSG00000162924	"REL proto-oncogene, NF-kB subunit"	Q04864	2	60881521-60931612	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 37.4"	"Cell type enhanced"	"Detected in all"		"Langerhans cells: 2061.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Daudi: 61.2;U-698: 109.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			CAB004404	Uncertain					NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 41: Macrophages - Immune response"			"CAB004404: AB_670194"	"unprognostic (2.77e-1)"	"unprognostic (2.05e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.23e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.11e-1)"	"unprognostic (7.15e-2)"	"unprognostic (2.15e-1)"	"unprognostic (5.87e-2)"	"unprognostic (4.38e-2)"	"unprognostic (4.37e-1)"	"unprognostic (2.82e-2)"	"unprognostic (2.91e-2)"	"unprognostic (3.53e-1)"	"unprognostic (3.85e-1)"	"unprognostic (3.66e-2)"	4.8	4.5	2.2	14.1	1.8	37.4	5.5	8.6	4.2	4.6	0.4	4.6	4.7	5.7	2.7	6.0	3.2	8.2	2.2	2.1	2.9	3.4	7.3	6.7	15.8	3.0	1.7	5.0	5.0	6.2	1.9	5.5	2.3	4.1	4.9	9.8	4.6	2.7	2.4	8.3	5.2	3.5	0.5	11.1	5.8	3.5	2.4	9.2	4.1	2.5	16.3	13.1	3.3	3.4	7.2	3.8	3.4	4.5	2.7	2.6	7.3	2.5	3.2	1.8	2.1	3.2	6.0	61.2	6.4	2.2	4.6	7.7	5.3	3.9	4.0	7.0	5.0	6.3	6.5	3.5	1.5	13.3	7.1	2.3	10.1	4.6	7.0	3.0	4.8	6.6	7.6	4.3	1.7	4.0	9.1	5.6	4.2	5.0	1.8	12.0	8.8	2.7	2.8	24.5	3.3	3.5	6.4	7.9	2.3	5.0	4.6	5.5	5.6	5.0	6.0	3.5	3.8	5.4	2.8	109.7	3.0	10.9	2.7	3.4	4.1	2.6	2.8	4.5	2.0	5.9	1.5	2.2	3.5	7.9	1.0	2.1	5.0	2.9	5.7	3.1	1.9	2.3	2.2	1.8	8.6	4.2	2.1	2.9	3.0	1.7	2.3	0.5	2.4	3.4	67.5	320.5	325.8	8.1	430.2	517.6	123.3	69.4	194.6	82.0	95.3	58.5	5.0	48.6	165.0	51.5	85.5	29.0	469.7	59.0	3.9	31.7	4.2	150.5	79.5	103.5	42.5	37.0	16.3	29.4	58.5	97.3	96.4	300.1	412.1	82.4	30.0	19.1	51.7	58.9	16.7	49.1	46.8	141.5	2061.4	3.4	15.5	463.9	135.2	42.2	451.1	21.3	145.2	8.5	9.2	35.1	46.6	23.7	119.5	99.7	34.3	7.7	153.1	56.2	13.1	65.9	73.9	51.5	38.4	158.0	463.1	77.6	303.7	21.3	50.1	260.6
SOX2		ENSG00000181449	"SRY-box transcription factor 2"	P48431	3	181711925-181714436	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Microphthalmia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 62.2;esophagus: 24.5"	"Group enriched"	"Detected in some"	6	"Basal squamous epithelial cells: 362.0;Muller glia cells: 383.5;Squamous epithelial cells: 229.1"	"Cancer enhanced"	"Detected in many"		"glioma: 136.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 277.0;HAP1: 118.6;NTERA-2: 226.2;U-251 MG: 54.0"	"Low region specificity"	"Detected in all"							"HPA045725, HPA062851, HPA071379, CAB079745"	Enhanced	Supported	Enhanced	Nucleoplasm		NA	NA				"Cluster 27: Brain & Skin - Unknown function"	"Cluster 12: NES - Nervous system development"	"Cluster 5: Muller glia cells - Visual perception"	Nucleoplasm		"CAB079745: , HPA045725: AB_2679431, HPA062851: , HPA071379: "	"unprognostic (1.80e-2)"	"unprognostic (3.18e-3)"	"unprognostic (5.69e-2)"	"unprognostic (6.96e-2)"	"unprognostic (2.74e-3)"	"unprognostic (1.60e-1)"	"unprognostic (1.79e-2)"	"unprognostic (4.48e-3)"	"unprognostic (1.71e-1)"	"unprognostic (4.38e-3)"	"unprognostic (1.83e-1)"	"unprognostic (7.68e-2)"	"unprognostic (3.81e-9)"	"unprognostic (1.12e-1)"	"unprognostic (2.12e-1)"	"unprognostic (1.26e-1)"	"unprognostic (1.12e-2)"	0.3	0.9	58.0	0.5	58.5	0.0	0.2	47.1	56.6	2.1	8.6	5.5	0.4	0.1	0.2	24.5	3.1	0.2	0.5	46.5	59.0	0.0	0.1	1.8	0.0	50.5	58.9	0.3	0.1	0.0	13.6	0.0	45.2	2.5	0.4	15.0	18.4	0.3	0.1	0.6	1.4	0.2	59.8	0.0	7.9	1.9	59.2	0.4	0.1	0.1	5.3	1.3	4.8	62.2	0.1	9.0	277.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	15.6	0.3	0.0	0.1	0.0	0.2	0.7	118.6	3.2	0.0	0.1	18.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.4	0.0	0.0	226.2	12.4	0.5	0.0	0.6	0.0	31.0	0.4	0.5	1.2	0.0	0.0	0.1	45.7	1.7	0.1	0.0	0.0	4.2	0.0	54.0	0.0	0.0	0.0	0.2	0.0	35.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	58.0	58.5	47.1	56.6	46.5	59.0	50.5	58.9	45.2	59.8	59.2	62.2	0.2	0.0	6.0	0.0	0.0	0.3	35.5	28.5	362.0	4.9	0.2	0.4	0.5	0.0	48.4	3.7	0.0	0.2	0.0	1.1	0.0	0.0	0.9	0.1	0.1	0.7	0.0	0.0	0.0	0.0	0.1	1.6	19.4	0.0	1.3	0.2	0.7	0.1	0.1	0.0	0.0	0.5	38.7	0.0	0.4	0.4	0.6	0.8	3.6	0.0	0.0	383.5	0.0	0.0	0.0	0.0	0.0	0.0	6.1	5.8	0.0	0.1	52.8	13.1	0.0	0.2	1.6	3.9	0.4	229.1	0.4	0.3	0.6	0.2	0.0	7.5